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Sample records for resistant american elm

  1. American Elm (Ulmus americana).

    Science.gov (United States)

    Newhouse, Andrew E; Schrodt, Franziska; Maynard, Charles A; Powell, William A

    2006-01-01

    American elm (Ulmus americana) is a valuable and sentimental tree species that was decimated by Dutch elm disease in the mid-20th century. Therefore, any methods for modifying American elm or enhancing disease resistance are significant. This protocol describes transformation and tissue culture techniques used on American elm. Leaf pieces containing the midvein and petiole are used for explants. Agrobacterium tumefaciens strain EHA105 is used for transformation, with the binary vector pSE39, containing CaMV35S/nptII as a selectable marker, ACS2/ESF39A as a putative resistance enhancing gene, and CaMV35S/GUS as a reporter.

  2. Generation of American elm trees with tolerance to Dutch elm disease through controlled crosses and selection

    Science.gov (United States)

    James M. Slavicek; Kathleen S. Knight

    2012-01-01

    The goal of our research and development efforts is to generate new and/or improved selections of the American elm (Ulmus americana L.) with tolerance/resistance to Dutch elm disease (DED). The approaches we are taking for this effort include: 1) controlled breeding using known DED -tolerant selections, 2) controlled breeding using DED-tolerant...

  3. Elm diseases

    Science.gov (United States)

    John W. Peacock

    1989-01-01

    Dutch elm disease was found in Cleveland, Ohio, in 1930, and is now in most of the contiguous 48 states. The disease is caused by a fungus that has killed millions of wild and planted elms. Losses have been the greatest in the eastern United States. The fungus attacks all elms, but our native species, American, slippery, and rock elm have little or no resistance to the...

  4. Genotype x environment interaction and growth stability of several elm clones resistant to Dutch elm disease

    Science.gov (United States)

    Alberto Santini; Francesco Pecori; Alessia L. Pepori; Luisa Ghelardini

    2012-01-01

    The elm breeding program carried out in Italy at the Institute of Plant Protection - Consiglio Nazionale delle Ricercje (CNR) during the last 40 years aimed to develop Dutch elm disease (DED)-resistant elm selections specific to the Mediterranean environment. The need for genotypes adapted to Mediterranean conditions was evident from the poor performance of the Dutch...

  5. Effects of induced water stress on leaf trichome density and foliar nutrients of three elm (Ulmus) species: implications for resistance to the elm leaf beetle.

    Science.gov (United States)

    Bosu, Paul P; Wagner, Michael R

    2007-06-01

    Seedlings of three elm species with variable susceptibility to the elm leaf beetle (Pyrrhalta luteola Müller) (Coleoptera: Chrysomelidae) were subjected to three water stress treatments (no stress, low stress, and high stress) in a greenhouse experiment. The species tested were Ulmus pumila L. (Siberian elm = highly susceptible), U. parvifolia Jacq. (Chinese elm = resistant), and U. americana L. (American elm = intermediate). The seedlings were analyzed for changes in the levels of selected host traits (trichome density, foliar concentration of nitrogen [N], phosphorus [P], potassium [K], calcium [Ca], magnesium [Mg], iron [Fe], and manganese [Mn]), some of which had previously been implicated in resistance to the elm leaf beetle. Density of leaf abaxial surface trichomes (simple, bulbous, and total trichomes) and foliar Fe and Mg concentrations increased significantly in the highly susceptible Siberian elms under water stress. In contrast, stress reduced trichome density in the moderately susceptible American elms, but it had no effect on levels of foliar mineral nutrients. The stress treatments had no influence on host traits in the resistant Chinese elms. The results suggest that environmental stress can alter plant traits that are likely involved in determining resistance of elms to the elm leaf beetle.

  6. Establishment and characterization of American elm cell suspension cultures

    Science.gov (United States)

    Steven M. Eshita; Joseph C. Kamalay; Vicki M. Gingas; Daniel A. Yaussy

    2000-01-01

    Cell suspension cultures of Dutch elm disease (DED)-tolerant and DED-susceptible American elms clones have been established and characterized as prerequisites for contrasts of cellular responses to pathogen-derived elicitors. Characteristics of cultured elm cell growth were monitored by A700 and media conductivity. Combined cell growth data for all experiments within a...

  7. American elm (Ulmus americana) in restoration plantings: a review

    Science.gov (United States)

    Kathleen S. Knight; Linda M. Haugen; Cornelia C. Pinchot; Paul G. Schaberg; James M. Slavicek

    2017-01-01

    The development of disease-tolerant American elm (Ulmus americana) trees has led to a need for reintroduction and restoration methods for the species. Here we review the current state of experimental work to inform reintroduction biology and restoration ecology of American elm. Much of this work is ongoing, and within several years the results will...

  8. Development of new Dutch Elm disease-tolerant selections for restoration of the American Elm in urban and forested landscapes

    Science.gov (United States)

    C.C. Pinchot; C.E. Flower; K.S. Knight; C. Marks; R. Minocha; D. Lesser; K. Woeste; P.G. Schaberg; B. Baldwin; D.M. Delatte; T.D. Fox; N. Hayes-Plazolles; B. Held; K. Lehtoma; S. Long; S. Mattix; A. Sipes; J.M. Slavicek

    2017-01-01

    The goal of our research and development efforts is to restore American elm (Ulmus americana) as a species in both natural and urban landscapes. Accomplishing this goal requires identification/generation of additional American elm cultivars that are tolerant to Dutch elm disease (DED) caused by Ophiostoma ulmi and O. novo-ulmi, and development of methods to reintroduce...

  9. American Elm clones of importance in DED tolerance studies

    Science.gov (United States)

    We present the background and characteristics of American elm clones that are commercially available or of interest in research on Dutch elm disease (DED) tolerance in the United States. The characteristics of interest include origin, ploidy level, whether available in nursery trade, evidence of DED...

  10. Plant signals during beetle (Scolytus multistriatus) feeding in American elm (Ulmus americana Planch).

    Science.gov (United States)

    Saremba, Brett M; Tymm, Fiona J M; Baethke, Kathy; Rheault, Mark R; Sherif, Sherif M; Saxena, Praveen K; Murch, Susan J

    2017-05-04

    American Elms were devastated by an outbreak of Dutch Elm Disease is caused by the fungus Ophiostoma novo-ulmi Brasier that originated in Asia and arrived in the early 1900s. In spite of decades of study, the specific mechanisms and disease resistance in some trees is not well understood. the fungus is spread by several species of bark beetles in the genus Scolytus, during their dispersal and feeding. Our objective was to understand elm responses to beetle feeding in the absence of the fungus to identify potential resistance mechanisms. A colony of Scolytus multistriatus was established from wild-caught beetles and beetles were co-incubated with susceptible or resistant American elm varieties in a controlled environment chamber. Beetles burrowed into the auxillary meristems of the young elm shoots. The trees responded to the beetle damage by a series of spikes in the concentration of plant growth regulating compounds, melatonin, serotonin, and jasmonic acid. Spikes in melatonin and serotonin represented a 7,000-fold increase over resting levels. Spikes in jasmonic acid were about 10-fold higher than resting levels with one very large spike observed. Differences were noted between susceptible and resistant elms that provide new understanding of plant defenses.

  11. Resistance to Dutch elm disease reduces presence of xylem endophytic fungi in Elms (Ulmus spp.).

    Science.gov (United States)

    Martín, Juan A; Witzell, Johanna; Blumenstein, Kathrin; Rozpedowska, Elzbieta; Helander, Marjo; Sieber, Thomas N; Gil, Luis

    2013-01-01

    Efforts to introduce pathogen resistance into landscape tree species by breeding may have unintended consequences for fungal diversity. To address this issue, we compared the frequency and diversity of endophytic fungi and defensive phenolic metabolites in elm (Ulmus spp.) trees with genotypes known to differ in resistance to Dutch elm disease. Our results indicate that resistant U. minor and U. pumila genotypes exhibit a lower frequency and diversity of fungal endophytes in the xylem than susceptible U. minor genotypes. However, resistant and susceptible genotypes showed a similar frequency and diversity of endophytes in the leaves and bark. The resistant and susceptible genotypes could be discriminated on the basis of the phenolic profile of the xylem, but not on basis of phenolics in the leaves or bark. As the Dutch elm disease pathogen develops within xylem tissues, the defensive chemistry of resistant elm genotypes thus appears to be one of the factors that may limit colonization by both the pathogen and endophytes. We discuss a potential trade-off between the benefits of breeding resistance into tree species, versus concomitant losses of fungal endophytes and the ecosystem services they provide.

  12. Resistance to Dutch Elm Disease Reduces Presence of Xylem Endophytic Fungi in Elms (Ulmus spp.)

    Science.gov (United States)

    Martín, Juan A.; Witzell, Johanna; Blumenstein, Kathrin; Rozpedowska, Elzbieta; Helander, Marjo; Sieber, Thomas N.; Gil, Luis

    2013-01-01

    Efforts to introduce pathogen resistance into landscape tree species by breeding may have unintended consequences for fungal diversity. To address this issue, we compared the frequency and diversity of endophytic fungi and defensive phenolic metabolites in elm (Ulmus spp.) trees with genotypes known to differ in resistance to Dutch elm disease. Our results indicate that resistant U. minor and U. pumila genotypes exhibit a lower frequency and diversity of fungal endophytes in the xylem than susceptible U. minor genotypes. However, resistant and susceptible genotypes showed a similar frequency and diversity of endophytes in the leaves and bark. The resistant and susceptible genotypes could be discriminated on the basis of the phenolic profile of the xylem, but not on basis of phenolics in the leaves or bark. As the Dutch elm disease pathogen develops within xylem tissues, the defensive chemistry of resistant elm genotypes thus appears to be one of the factors that may limit colonization by both the pathogen and endophytes. We discuss a potential trade-off between the benefits of breeding resistance into tree species, versus concomitant losses of fungal endophytes and the ecosystem services they provide. PMID:23468900

  13. Resistance to Dutch elm disease reduces presence of xylem endophytic fungi in Elms (Ulmus spp..

    Directory of Open Access Journals (Sweden)

    Juan A Martín

    Full Text Available Efforts to introduce pathogen resistance into landscape tree species by breeding may have unintended consequences for fungal diversity. To address this issue, we compared the frequency and diversity of endophytic fungi and defensive phenolic metabolites in elm (Ulmus spp. trees with genotypes known to differ in resistance to Dutch elm disease. Our results indicate that resistant U. minor and U. pumila genotypes exhibit a lower frequency and diversity of fungal endophytes in the xylem than susceptible U. minor genotypes. However, resistant and susceptible genotypes showed a similar frequency and diversity of endophytes in the leaves and bark. The resistant and susceptible genotypes could be discriminated on the basis of the phenolic profile of the xylem, but not on basis of phenolics in the leaves or bark. As the Dutch elm disease pathogen develops within xylem tissues, the defensive chemistry of resistant elm genotypes thus appears to be one of the factors that may limit colonization by both the pathogen and endophytes. We discuss a potential trade-off between the benefits of breeding resistance into tree species, versus concomitant losses of fungal endophytes and the ecosystem services they provide.

  14. The ecological role of American elm (Ulmus americana L.) in floodplain forests of northeastern North America

    Science.gov (United States)

    Christian O. Marks

    2017-01-01

    Before Dutch elm disease, the American elm (Ulmus americana L.) was a leading dominant tree species in the better drained parts of floodplain forests where flooding occurs about 1 percent of the time. Although still common in these habitats today, U. americana now rarely lives long enough to reach the forest canopy because elm...

  15. Protoplast-to-plant regeneration of American elm (Ulmus americana).

    Science.gov (United States)

    Jones, A M P; Shukla, M R; Biswas, G C G; Saxena, P K

    2015-05-01

    This study describes a protocol for regeneration of plants from cell suspension-derived protoplasts of American elm (Ulmus americana). Efficient protoplast isolation was achieved from a two-phase culture system through the incorporation of 100 μM 2-aminoindan-2-phosphonic acid, with a yield of approximately 2 × 10(6) protoplasts/ml packed cell volume. Isolated protoplasts failed to survive in liquid or alginate bead culture systems but initiated and continued to divide when embedded in low melting point agarose beads. Protoplast-derived callus proliferated and differentiated into shoot buds in response to 10 or 20 μM thidiazuron. Differentiated buds elongated and continued to proliferate on elm shoot medium supplemented with 3.0 μM GA3. The protoplast-derived shoots rooted and acclimatized to greenhouse conditions and continued to grow. This system provides the first protoplast-to-plant regeneration system for American elm and provides a framework for the development of protoplast fusion or genome editing technologies.

  16. Inhibition of phenylpropanoid biosynthesis increases cell wall digestibility, protoplast isolation, and facilitates sustained cell division in American elm (Ulmus americana).

    Science.gov (United States)

    Jones, A Maxwell P; Chattopadhyay, Abhishek; Shukla, Mukund; Zoń, Jerzy; Saxena, Praveen K

    2012-05-30

    Protoplast technologies offer unique opportunities for fundamental research and to develop novel germplasm through somatic hybridization, organelle transfer, protoclonal variation, and direct insertion of DNA. Applying protoplast technologies to develop Dutch elm disease resistant American elms (Ulmus americana L.) was proposed over 30 years ago, but has not been achieved. A primary factor restricting protoplast technology to American elm is the resistance of the cell walls to enzymatic degradation and a long lag phase prior to cell wall re-synthesis and cell division. This study suggests that resistance to enzymatic degradation in American elm was due to water soluble phenylpropanoids. Incubating tobacco (Nicotiana tabacum L.) leaf tissue, an easily digestible species, in aqueous elm extract inhibits cell wall digestion in a dose dependent manner. This can be mimicked by p-coumaric or ferulic acid, phenylpropanoids known to re-enforce cell walls. Culturing American elm tissue in the presence of 2-aminoindane-2-phosphonic acid (AIP; 10-150 μM), an inhibitor of phenylalanine ammonia lyase (PAL), reduced flavonoid content, decreased tissue browning, and increased isolation rates significantly from 11.8% (±3.27) in controls to 65.3% (±4.60). Protoplasts isolated from callus grown in 100 μM AIP developed cell walls by day 2, had a division rate of 28.5% (±3.59) by day 6, and proliferated into callus by day 14. Heterokaryons were successfully produced using electrofusion and fused protoplasts remained viable when embedded in agarose. This study describes a novel approach of modifying phenylpropanoid biosynthesis to facilitate efficient protoplast isolation which has historically been problematic for American elm. This isolation system has facilitated recovery of viable protoplasts capable of rapid cell wall re-synthesis and sustained cell division to form callus. Further, isolated protoplasts survived electrofusion and viable heterokaryons were produced. Together

  17. Height preference of Scolytus schevyrewi Semenov, the banded elm bark beetle of American elm, Ulmus americana

    Science.gov (United States)

    S. McElwey; J. F. Negron; J. Withrow

    2007-01-01

    Scolytus schevyrewi Semenov, the banded elm bark beetle, was first detected in North America in April 2003 in Colorado and Utah by the Rapid Detection and Response Pilot Project sponsored by APHIS and USDA Forest Service, Forest Health Protection. It was captured in Lindgren funnel traps baited with a-pinene, ethanol, and the Ips typographus...

  18. Melatonin enhances the recovery of cryopreserved shoot tips of American elm (Ulmus americana L.).

    Science.gov (United States)

    Uchendu, Esther E; Shukla, Mukund R; Reed, Barbara M; Saxena, Praveen K

    2013-11-01

    Climate change and global migrations of people and goods have exposed trees to new diseases and abiotic challenges that threaten the survival of species. In vitro germplasm storage via cryopreservation is an effective tool to ensure conservation of tree species, but plant cells and tissues are exposed to multiple stresses during the cryopreservation process. The current study was designed to evaluate the potential of melatonin to improve survival through the process of cryopreservation. Shoot tips of in vitro-grown plantlets and dormant winter buds of American elm were successfully cryopreserved in liquid nitrogen (LN) at -196°C under controlled environmental conditions following melatonin treatment and cold acclimation with either vitrification or encapsulation–vitrification protocols. Explants had optimal regrowth following cryopreservation when treated with the plant vitrification solution#2 (PVS2) for 10 min. Supplementation of both preculture and regrowth media with melatonin significantly enhanced regrowth of frozen shoots compared with the untreated control (P < 0.05). Approximately 80–100% of shoot explants grew under optimized conditions using melatonin-enriched media. Shoot tips of dormant winter buds consistently produced nearly 100% regrowth with both techniques. The main steps of the optimized protocol are14-day cold-acclimated cultures exposed to preculture medium with 0.1–0.5 lM melatonin for 24 hr, application of PVS2 for 10 min, rapid cooling in LN, rapid rewarming, removal of cryoprotectants, and recovery on a medium supplemented with 0.1–0.5 lM melatonin. Our results demonstrate the usefulness of the antioxidant melatonin for long-term storage of naturally resistant elm germplasm.

  19. Elms and Dutch elm disease: a quick overview

    Science.gov (United States)

    Michael. Marcotrigiano

    2017-01-01

    In the 1930s Dutch elm disease (DED) was accidentally introduced from Europe into the United States. It had a devastating impact on American elm (Ulmus americana) and its relatives in urban and riparian environments. In the United States, the three-part pathosystem for DED is unique in that the affected elm species are North American, the pathogen originated in Asia,...

  20. Dutch elm disease pathogen transmission by the banded elm bark beetle Scolytus schevyrewi

    Science.gov (United States)

    W. R. Jacobi; R. D. Koski; J. F. Negron

    2013-01-01

    Dutch Elm Disease (DED) is a vascular wilt disease of Ulmus species (elms) incited in North America primarily by the exotic fungus Ophiostoma novo-ulmi. The pathogen is transmitted via root grafts and elm bark beetle vectors, including the native North American elm bark beetle, Hylurgopinus rufipes and the exotic smaller European elm bark beetle, Scolytus multistriatus...

  1. First Report of ‘Candidatus Phytoplasma trifolii’-Related Strain of 16SrVI-A Phytoplasma Subgroup, Associated with Elm Yellows Disease in American Elm ( Ulmus americana L.) in Ohio, U.S.A

    Science.gov (United States)

    C.E. Flower; N. Hayes-Plazolles; J.M. Slavicek; C. Rosa

    2018-01-01

    During the investigation of the sudden and early onset of yellowing and mortality of American elm (Ulmus americana L.) trees at the USDA Forest Service Northern Research Station in Delaware, OH, a phytoplasma of the clover proliferation group (16SrVI) was detected as the putative causal agent of the disease outbreak.

  2. Fourier transform-infrared spectroscopy as a new method for evaluating host resistance in the Dutch elm disease complex.

    Science.gov (United States)

    Martín, J A; Solla, A; Woodward, S; Gil, L

    2005-10-01

    Resistance of elms (Ulmus spp.) to the pathogenic fungus Ophiostoma novo-ulmi Brasier depends on chemical and anatomical factors that confine the spread of the pathogen in the vascular system of the host. This study focused on detecting chemical differences in 4-year-old Ulmus minor Mill. seedlings before and after inoculation with a virulent O. novo-ulmi isolate. According to symptom development over 60 days, the trees were divided into resistant (0-33% wilting) and susceptible (67-100% wilting) groups. Histochemical tests and Fourier transform-infrared (FT-IR) spectroscopy analysis were performed on transverse sections of 2-year-old twigs, 2 days before and 40 days after inoculation. Although histochemical tests did not clearly discriminate susceptible from resistant elms, chemical differences between resistant, susceptible and control trees were detected by FT-IR. The average spectrum for resistant tree samples had higher absorbance peaks than the spectra from the susceptible and control samples, indicating increased formation of lignin and suberin. The roles of lignin and suberin in the resistance of the elms against O. novo-ulmi and the usefulness and sensitivity of the FT-IR technique for analyzing metabolic changes caused by pathogens in plants are discussed.

  3. Asian American Cultural Resistance.

    Science.gov (United States)

    Libretti, Tim

    1997-01-01

    Explores the encounter of Marxism and Asian American literary theory and imagines an Asian American Marxism. To do so requires theorizing race, class, and gender not as substantive categories of antagonisms but as complementary and coordinated elements of a totality of social relations structuring racial patriarchal capitalism. (SLD)

  4. HOW to Differentiate Dutch Elm Disease from Elm Phloem Necrosis

    Science.gov (United States)

    Lester Paul Gibson; Arthur R. Hastings; Leon A. LeMadeliene

    1981-01-01

    Dutch elm disease (DED) and elm phloem necrosis are the two most serious diseases of elm in the United States (Figs. 1 and 2). Most native species of elm are susceptible to both diseases. Dutch elm disease is caused by a fungus, Ceratocystis u1mi (Buisman) C. Moreau, and is transmitted by two species of elm bark beetles-the smaller European elm bark beetle, Scolytus...

  5. Ten-year performance of the United States national elm trial

    Science.gov (United States)

    Jason J. Griffin; William R. Jacobi; E. Gregory McPherson; Clifford S. Sadof; James R. McKenna; Mark L. Gleason; Nicole Ward Gauthier; Daniel A. Potter; David R. Smitley; Gerard C. Adams; Ann Brooks Gould; Christian R. Cash; James A. Walla; Mark C. Starrett; Gary Chastagner; Jeff L. Sibley; Vera A. Krischik; Adam F. Newby

    2017-01-01

    Ulmus americana (American elm) was an important urban tree in North America prior to the introduction of the Dutch elm disease pathogen in 1930. Subsequently, urban and community forests were devastated by the loss of large canopies. Tree improvement programs produced disease tolerant American and Eurasian elm cultivars and introduced them into the...

  6. The banded elm bark beetle: A new threat to elms in North America

    Science.gov (United States)

    Jose F. Negron; Jeffrey J. Witcosky; Robert J. Cain; James R. LaBonte; Donald A. Duerr; Sally J. McElwey; Jana C. Lee; Steven J. Seybold

    2005-01-01

    An exotic bark beetle from Asia, the banded elm bark beetle, Scolytus schevyrewi, has been discovered in 21 states of the United States. Although its point of entry is not known, a survey of museum specimens suggests that it has been in the US for at least 10 years. It is most abundant in western states, attacks primarily American and Siberian elms, and carries spores...

  7. Cephalosporium Wilt of Elm in the Lower Mississippi Valley

    Science.gov (United States)

    T. H. Filer; F. I. McCracken; E. R. Toole

    1968-01-01

    Dead and dying American elms (Ulmus americana) and cedar elms (U. crassifolia) were observed on the Delta Experimental Forest, Stoneville, Mississippi, and in Desha County, Arkansas, near the Mississippi River (about 30 miles northwest of the experimental forest) during August 1967. The only fungus consistently isolated from these...

  8. Ulmus crassifolia Nutt. Cedar Elm

    Science.gov (United States)

    John J. Stransky; Sylvia M. Bierschenk

    1990-01-01

    Cedar elm (Ulmus cassifolia) grows rapidly to medium or large size in the Southern United States and northeastern Mexico, where it may sometimes be called basket elm, red elm, southern rock elm, or olmo (Spanish) It usually is found on moist, limestone soils along water courses with other bottomland trees, but it also paws on dry limestone hills. The...

  9. New Perspectives for the Use of Elms as Street Trees

    NARCIS (Netherlands)

    Hiemstra, J.A.; Buiteveld, J.

    2010-01-01

    As a result of the continuing problems with Dutch elm disease in the Netherlands the dominant role of elm as a street tree has diminished strongly in the last decades of the 20th century. New cultivars with increased resistance to DED are used to a limited extent only. This paper reports on the

  10. Gene expression trade-offs between defence and growth in English elm induced by Ophiostoma novo-ulmi.

    Science.gov (United States)

    Perdiguero, Pedro; Sobrino-Plata, Juan; Venturas, Martin; Martín, Juan Antonio; Gil, Luis; Collada, Carmen

    2018-01-01

    Wilt diseases caused by vascular pathogens include some of the most damaging stresses affecting trees. Dutch elm disease (DED), caused by the fungus Ophiostoma novo-ulmi, destroyed most of North American and European elm populations in the 20th century. The highly susceptible English elm, also known as Atinian clone, suffered the highest mortality rates during the last pandemic event, probably due to its lack of genetic diversity. To study the DED pathosystem, we inoculated English elm ramets with O. novo-ulmi and evaluated xylem anatomy, molecular response, and disease symptoms. The high DED susceptibility of the clone was linked to xylem structure. The transcript levels changed significantly for 1,696 genes during O. novo-ulmi invasion. Genes covering different steps of the plant immune system were identified, many of which showed homology with Arabidopsis thaliana genes involved in systemic acquired resistance. Induction of several pathogenesis-related proteins and repression of fasciclin-like arabinogalactan proteins and other cell wall biosynthesis pathways evidence unbalanced costs between growth and defence mechanisms far from the inoculation point. This study sheds light on elm molecular defence mechanisms against DED. © 2017 John Wiley & Sons Ltd.

  11. Susceptibility of 32 elm species and hybrids (Ulmus spp.) to the elm leaf beetle (Coleoptera: Chrysomelidae) under field conditions in Arizona.

    Science.gov (United States)

    Bosu, Paul P; Miller, Fredric; Wagner, Michael R

    2007-12-01

    We evaluated elm leaf beetle, Pyrhalta luteola (Müller) (Coleoptera: Chrysomelidae), defoliation of 32 elm species or hybrids (taxa) established under field conditions in Holbrook, AZ. Percentage of defoliation, number of eggs, and number of larvae were estimated on randomly selected 15-cm shoot lengths annually in July, from 1996 to 2001. The following nine taxa consistently sustained 15-46% mean overall defoliation: 1) Siberian elm, U. pumila L.; 2) 'Dropmore' elm, U. pumila; 3) 'Camperdownii' elm, U. glabra Huds.; 4) 'Regal' elm, U. glabra x U. carpinifolia Gledisch x U. pumila); 5) 'Sapporo Autumn Gold' elm (U. pumila x U. japonica Sang.); 6) 'New Horizon' elm (U. pumila x U. japonica); 7) 'Charisma' elm [(U. japonica x U. wilsoniana Schneid.) x (U. japonica x U. pumila)]; 8) 'W2115-1' elm (U. parvifolia Jacq. x U. procera Salisb.); and 9) 'Homestead' elm [(U. hollandica Mill. x U. carpinifolia) x (U. pumila-racemosa Dieck x U. carpinifolia)]. Percentage of defoliation was significantly low on four Chinese elm (U. parvifolia) cultivars ('Allee', 'Athena', 'Glory'/lace bark, and 'Kings Choice'). Percentage of defoliation was also low on seven Asian elms (including U. chemnoui Cheng, U. bergmaniana Sneid., U. szechuanica Fang, and species of the U. davidiana Planch. complex [U. davidiana, U. japonica, U. wilsoniana, and U. propinqua Koidz.]) and the American elm (U. americana L.) 'Valley Forge'. Percentage of defoliation and the number of eggs or larvae per plant were highly correlated. The results of this study are generally consistent with results of past laboratory screening trials.

  12. Endophytic fungi in elms

    OpenAIRE

    Blumenstein, Kathrin

    2015-01-01

    Integrated pest management calls for new biocontrol solutions in management of forest diseases. Endophytic fungi that are commonly found in tree tissue may have potential in biocontrol. However, the links between endophyte status and disease tolerance are still unclear, and we know little about the mechanisms by which the endophytes can influence tree pathogens. The first goal of the thesis was to compare the endophyte status in elm (Ulmus spp.) trees with low vs. high susceptibility t...

  13. Identification of native and hybrid elms in Spain using isozyme gene markers.

    Science.gov (United States)

    Cogolludo-Agustín, M A; Agúndez, D; Gil, L

    2000-08-01

    Two elm taxa occur naturally in the Iberian Peninsula: the Field elm (Ulmus minor) and the Wych elm (U. glabra). In addition, a third taxon, the foreign Siberian elm (U. pumila), was probably introduced in the 16th century as an ornamental tree and has spread spontaneously throughout the Peninsula. The natural hybridization between U. minor and U. pumila produced new individuals whose morphological traits appear to be mixed. Ulmus pumila, as well as its hybrids, has a high resistance to Dutch elm disease (DED). For this reason, it is commonly used in breeding programmes. Extensive hybridization and the high mortality produced by the last DED epidemic have endangered the conservation of the native elm. In this study, isozyme analyses are used to characterize the taxa U. minor and U. pumila. Siberian elms from Spain and China are compared with the native U. minor. Siberian elm produces isozyme patterns that completely differentiate it from U. minor. Three loci are completely different between the species: 6Pgd2, Mdh1 and Prx2. Isozyme markers can also be used to distinguish native elms from the hybrids that have evolved for generations.

  14. Improving germination of red elm (Ulmus rubra), gray alder (Alnus incana), and buffaloberry (Shepherdia canadensis) seeds with gibberellic acid

    Science.gov (United States)

    Brenda Morales; Charles Barden; Cheryl Boyer; Jason Griffin; Lillian Fisher; Joni Thompson

    2012-01-01

    Red elm (Ulmus rubra), gray alder (Alnus incana), and buffaloberry (Shepherdia canadensis) are considered important plants for many Native American tribes in the United States. Native Americans use these 3 species for a variety of traditional and medicinal purposes. For example, red elm is still the preferred firewood for the cultural ceremonies of several tribes....

  15. The impact of large ELMs on JET

    Energy Technology Data Exchange (ETDEWEB)

    Pitts, R.A., E-mail: richard.pitts@iter.or [JET-EFDA Culham Science Centre, Abingdon OX14 3DB (United Kingdom); CRPP-EPFL, Association EURATOM-Confederation Suisse, CH-1015 Lausanne (Switzerland); Arnoux, G. [JET-EFDA Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Euratom/UKAEA Fusion Association, Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Beurskens, M. [Euratom/UKAEA Fusion Association, Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Eich, T. [Max-Planck-Institut fuer Plasmaphysik, IPP-EURATOM Association, D-85748 Garching (Germany); Fundamenski, W. [Euratom/UKAEA Fusion Association, Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Huber, A. [Institut fuer Energieforschung-Plasmaphysik, Forschungszentrum Juelich, Association EURATOM-FZJ (Germany); Loarte, A. [ITER Organization, CEA-Cadarache Centre, 13108 Saint Paul les Durance (France); Marki, J. [CRPP-EPFL, Association EURATOM-Confederation Suisse, CH-1015 Lausanne (Switzerland); Stamp, M.F.; Andrew, P. [Euratom/UKAEA Fusion Association, Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Brezinsek, S.; Esser, H.G. [Institut fuer Energieforschung-Plasmaphysik, Forschungszentrum Juelich, Association EURATOM-FZJ (Germany); Gulejova, B. [CRPP-EPFL, Association EURATOM-Confederation Suisse, CH-1015 Lausanne (Switzerland); Jachmich, S. [LPP, ERM/KMS, Association Euratom-Belgian State, B-1000 Brussels (Belgium); Kreter, A. [Institut fuer Energieforschung-Plasmaphysik, Forschungszentrum Juelich, Association EURATOM-FZJ (Germany); Luna, E. de la [ITER Organization, CEA-Cadarache Centre, 13108 Saint Paul les Durance (France); Matthews, G.F. [Euratom/UKAEA Fusion Association, Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Philipps, V. [Institut fuer Energieforschung-Plasmaphysik, Forschungszentrum Juelich, Association EURATOM-FZJ (Germany); Solano, E. [Associacion Euratom/CIEMAT Para Fusion, Madrid (Spain)

    2009-06-15

    To ensure sufficient divertor target lifetime, the loss in plasma stored energy due to ELMs in ITER should be restricted to DELTAW{sub ELM} <= 1 MJ. Only in JET, by virtue of its size, can such energies be approached. This contribution examines the impact of large, Type I ELMs in high current H-mode JET discharges with ITER-relevant pedestal characteristics. The ELMs provoke strong radiation losses, mostly confined to the inner divertor volume. Although the data are scattered, the average magnitude of this loss is DELTAE{sub RAD} approx 0.5DELTAW{sub ELM}, for DELTAW{sub ELM} < 0.55 MJ. For higher DELTAW{sub ELM}, greater fractional radiation losses occur, reaching approx0.7DELTAW{sub ELM} at DELTAW{sub ELM} approx 0.9 MJ, indicating enhanced impurity release. Even at the highest ELM energies, peak divertor target surface temperatures are too low for carbon sublimation, suggesting that thermal decomposition and/or ablation of thick co-deposited layers on the inner target may be occurring. On average, across the range of energies studied, ELMs are found to deposit between 3-4.5% of DELTAW{sub ELM} on main wall limiters. When applied to the data for a specific discharge in the series, the model of ELM filament parallel energy losses developed at JET requires radial ELM velocities in the interval 0.1-0.65 km s{sup -1} to explain these deposited energy fractions.

  16. Formulation and application of methoxychlor for elm bark beetle control

    Science.gov (United States)

    R. A. Cuthbert; J. H. Barger; A. C. Lincoln; P. A. Reed

    1973-01-01

    American elm trees, Ulmus americana L., were sprayed with different formulations of methoxychlor by mistblower, hydraulic sprayer or helicopter. Twig-crotches were collected from sprayed trees for GLC assay and Scolytus multistriatus (Marsham) bioassay. Hydraulic deposits were heaviest but the mistblower was more efficient in terms...

  17. Anatomical and nutritional factors associated with susceptibility of elms (Ulmus spp.) to the elm leaf beetle (Coleoptera: Chrysomelidae).

    Science.gov (United States)

    Bosu, Paul P; Wagner, Michael R

    2008-06-01

    A wide range of susceptibility exists across elm (Ulmus) species and hybrids to the elm leaf beetle, Pyrrhalta luteola (Müller) (Coleoptera: Chrysomelidae). We evaluated various elm species, hybrids, or cultivars (taxa) growing in an experimental plantation in the city of Holbrook, AZ, for leaf anatomical (toughness and trichome density) and nutritional (minerals and sugars) traits that may be associated with host resistance. Leaf toughness and percentage of defoliation (susceptibility) were not correlated. However, we found weak negative correlations between percentage of defoliation and density of trichomes on the leaf abaxial surface. Of the 11 leaf nutrients examined, concentrations of iron and phosphorus correlated inversely with percentage of defoliation. The remaining nine traits did not show any correlation with percentage of defoliation. We concluded that individual anatomical and nutritional traits of elm species/hybrids do not seem to create a strong barrier to elm leaf beetle defoliation. However, the results from a stepwise multiple regression analysis indicated that collectively, these traits may play an important role in determining susceptibility.

  18. The Glenwood Estate: our 32-year experience using Arbotect® 20-S to control Dutch elm disease

    Science.gov (United States)

    William L. MacDonald; Mark L. Double; Cameron M. Stauder; Kemp. Winfree

    2017-01-01

    We report a case study that demonstrates the successful use of the fungicide Arbotect® 20-S to protect American elms (Ulmus americana) from Dutch elm disease at a historic site in Charleston, WV. Standard injection protocols were used every 3 to 4 years to deliver the chemical into the root flares. Twelve of the original 16 trees remain 34 years...

  19. Dutch Elm Disease Control: Intensive Sanitation and Survey Economics

    Science.gov (United States)

    William N., Jr. Cannon; Jack H. Barger; David P. Worley

    1977-01-01

    Recent research has shown that prompt removal of diseased elms reduces the incidence of Dutch elm disease more than sanitation practice that allows diseased elms to remain standing into the dormant season. The key to prompt removal is repeated surveys to detect diseased elms as early as possible. Intensive sanitation can save more elms and cost less than the more...

  20. ELM mitigation with pellet ELM triggering and implications for PFCs and plasma performance in ITER

    International Nuclear Information System (INIS)

    Baylor, L.R.; Lang, P.T.; Allen, S.L.; Combs, S.K.; Commaux, N.; Evans, T.E.; Fenstermacher, M.E.; Huijsmans, G.; Jernigan, T.C.; Lasnier, C.J.; Leonard, A.W.; Loarte, A.; Maingi, R.; Maruyama, S.; Meitner, S.J.; Moyer, R.A.; Osborne, T.H.

    2015-01-01

    The triggering of rapid small edge localized modes (ELMs) by high frequency pellet injection has been proposed as a method to prevent large naturally occurring ELMs that can erode the ITER plasma facing components (PFCs). Deuterium pellet injection has been used to successfully demonstrate the on-demand triggering of edge localized modes (ELMs) at much higher rates and with much smaller intensity than natural ELMs. The proposed hypothesis for the triggering mechanism of ELMs by pellets is the local pressure perturbation resulting from reheating of the pellet cloud that can exceed the local high-n ballooning mode threshold where the pellet is injected. Nonlinear MHD simulations of the pellet ELM triggering show destabilization of high-n ballooning modes by such a local pressure perturbation. A review of the recent pellet ELM triggering results from ASDEX Upgrade (AUG), DIII-D, and JET reveals that a number of uncertainties about this ELM mitigation technique still remain. These include the heat flux impact pattern on the divertor and wall from pellet triggered and natural ELMs, the necessary pellet size and injection location to reliably trigger ELMs, and the level of fueling to be expected from ELM triggering pellets and synergy with larger fueling pellets. The implications of these issues for pellet ELM mitigation in ITER and its impact on the PFCs are presented along with the design features of the pellet injection system for ITER

  1. ELM mitigation with pellet ELM triggering and implications for PFCs and plasma performance in ITER

    Science.gov (United States)

    Baylor, L. R.; Lang, P. T.; Allen, S. L.; Combs, S. K.; Commaux, N.; Evans, T. E.; Fenstermacher, M. E.; Huijsmans, G.; Jernigan, T. C.; Lasnier, C. J.; Leonard, A. W.; Loarte, A.; Maingi, R.; Maruyama, S.; Meitner, S. J.; Moyer, R. A.; Osborne, T. H.

    2015-08-01

    The triggering of rapid small edge localized modes (ELMs) by high frequency pellet injection has been proposed as a method to prevent large naturally occurring ELMs that can erode the ITER plasma facing components (PFCs). Deuterium pellet injection has been used to successfully demonstrate the on-demand triggering of edge localized modes (ELMs) at much higher rates and with much smaller intensity than natural ELMs. The proposed hypothesis for the triggering mechanism of ELMs by pellets is the local pressure perturbation resulting from reheating of the pellet cloud that can exceed the local high-n ballooning mode threshold where the pellet is injected. Nonlinear MHD simulations of the pellet ELM triggering show destabilization of high-n ballooning modes by such a local pressure perturbation. A review of the recent pellet ELM triggering results from ASDEX Upgrade (AUG), DIII-D, and JET reveals that a number of uncertainties about this ELM mitigation technique still remain. These include the heat flux impact pattern on the divertor and wall from pellet triggered and natural ELMs, the necessary pellet size and injection location to reliably trigger ELMs, and the level of fueling to be expected from ELM triggering pellets and synergy with larger fueling pellets. The implications of these issues for pellet ELM mitigation in ITER and its impact on the PFCs are presented along with the design features of the pellet injection system for ITER.

  2. American elm in mine land reforestation

    Science.gov (United States)

    M.B. Adams; P. Angel; C. Barton; J. Slavicek

    2015-01-01

    Reforestation of mined land in the Appalachians realizes many important benefits and provides important ecosystem services. Because much of the reclaimed mine lands in Appalachia were previously in forest, reclaiming these drastically disturbed areas to forests is desirable, feasible and cost-effective. The Forestry Reclamation Approach (FRA) provides a five-step...

  3. Electrical testing and performance evaluation of 1:1 prototype JET ELM control coils

    Energy Technology Data Exchange (ETDEWEB)

    Kanabar, Deven, E-mail: deven@ipr.res.in; Roy, Swati; Ghate, Mahesh; Raj, Piyush; Kundu, Ananya; Kumar, Nitish; Bhavsar, Dhaval; Panchal, Arun; Pradhan, Subrata, E-mail: pradhan@ipr.res.in

    2016-12-15

    Highlights: • An appropriate 1:1 prototype Small and Large ELM coils for JET have been successfully manufactured using indigenous technologies. • ELM coils have been tested extensively to verify and validated their performance with respect to operational requirement of JET. • The test results confirm and validate the electrical performance of ELM coils. - Abstract: Magnet Technology Development Division at Institute for Plasma research is engaged in extensive R & D for appropriate technologies towards manufacturing of Edge Localized Mode (ELM) magnets for Large Tokamak such as Joint European Torus (JET) as well as for Steady State Superconducting Tokamak (SST-1). Under this project, manufacturing of 1:1 prototype of Large and Small JET ELM control coils (CC) is completed incorporating indigenously developed manufacturing and insulation technologies. Performance evaluation of both the types of coil has been completed for its current carrying capability and insulation resistance as required by various operational scenarios of JET. Experimental setups, test procedures and measurements for electrical characterization of both type of ELM control coil has been discussed in this paper.

  4. Rotation Breaking Induced by ELMs on EAST

    DEFF Research Database (Denmark)

    Xiong, H.; Xu, G.; Sun, Y.

    Spontaneous rotation has been observed in LHCD H-mode plasmas with type III ELMs (edge localized modes) on EAST, and it revealed that type III ELMs can induce the loss of both core and edge toroidal rotation. Here we work on the breaking mechanism during the ELMs. Several large tokamaks have...... of magnetic surface, thus generate NTV (neoclassical toroidal viscosity) torque that affects toroidal rotation. We adopt 1cm maximum edge magnetic surface displacement from experimental observation, and our calculation shows that the edge torque is about 0.35 N/m2, and the core very small. The expected...

  5. Domain Adaption Based on ELM Autoencoder

    Directory of Open Access Journals (Sweden)

    Wan-Yu Deng

    2017-01-01

    Full Text Available We propose a new ELM Autoencoder (ELM-AE based domain adaption algorithm which describes the subspaces of source and target domain by ELM-AE and then carries out subspace alignment to project different domains into a common new space. By leveraging nonlinear approximation ability and efficient one-pass learning ability of ELM-AE, the proposed domain adaption algorithm can efficiently seek a better cross-domain feature representation than linear feature representation approaches such as PCA to improve domain adaption performance. The widely experimental results on Office/Caltech-256 datasets show that the proposed algorithm can achieve better classification accuracy than PCA subspace alignment algorithm and other state-of-the-art domain adaption algorithms in most cases.

  6. Use of protoplast, cell, and shoot tip culture in an elm germ plasm improvement program

    Science.gov (United States)

    R. Daniel Lineberger; M.B. Sticklen; P.M. Pijut; Mark A. Kroggel; C.V.M. Fink; S.C. Domir

    1990-01-01

    An elm germplasm improvement program was established using three distinct approaches: (1) development of protoplast regeneration protocols with the goal of attempting somatic hybridization between Ulmus americana and disease resistant hybrids; (2) evaluation of the extent of somaclonal variation in plants regenerated from protoplasts; and (3)...

  7. Solitary magnetic perturbations at the ELM onset

    Science.gov (United States)

    Wenninger, R. P.; Zohm, H.; Boom, J. E.; Burckhart, A.; Dunne, M. G.; Dux, R.; Eich, T.; Fischer, R.; Fuchs, C.; Garcia-Munoz, M.; Igochine, V.; Hölzl, M.; Luhmann N., C., Jr.; Lunt, T.; Maraschek, M.; Müller, H. W.; Park, H. K.; Schneider, P. A.; Sommer, F.; Suttrop, W.; Viezzer, E.; the ASDEX Upgrade Team

    2012-11-01

    Tokamak H-mode plasmas frequently exhibit edge-localized modes (ELMs). ELMs allow maintaining sufficient plasma purity and thus enable stationary H-mode. On the other hand in a future device ELMs may cause divertor power flux densities far in excess of tolerable material limits. The size of the energy loss per ELM is determined by saturation effects in the non-linear phase of the ELM, which at present is hardly understood. ASDEX Upgrade is now equipped with a set of fast sampling diagnostics, which is well suited to investigate the chain of events around the ELM crash with appropriate temporal resolution (⩽10 µs). Solitary magnetic perturbations (SMPs) are identified as dominant features in the radial magnetic fluctuations below 100 kHz. They are typically observed close (±100 µs) to the onset of pedestal erosion. SMPs are field aligned structures rotating in the electron diamagnetic drift direction with perpendicular velocities of about 10 km s-1. A comparison of perpendicular velocities suggests that the perturbation evoking SMPs is located at or inside the separatrix. Analysis of very pronounced examples showed that the number of peaks per toroidal turn is 1 or 2, which is clearly lower than the corresponding numbers in linear stability calculations. In combination with strong peaking of the magnetic signals this results in a solitary appearance resembling modes like palm tree modes, edge snakes or outer modes. This behaviour has been quantified as solitariness and correlated with main plasma parameters. SMPs may be considered as a signature of the non-linear ELM phase originating at the separatrix or further inside. Thus they provide a handle to investigate the transition from linear to non-linear ELM phase. By comparison with data from gas puff imaging processes in the non-linear phase at or inside the separatrix and in the scrape-off layer (SOL) can be correlated. A connection between the passing of an SMP and the onset of radial filament propagation has

  8. ELMs, strike point jumps and SOL currents

    International Nuclear Information System (INIS)

    Solano, Emilia R.; Jachmich, S.; Villone, F.; Hawkes, N.; Guenther, K.; Korotkov, A.; Stamp, M.; Andrew, P.; Conboy, J.; Mattews, G.F.; Corre, Y.; Loarte, A.; Pitts, R.A.; Cenedese, A.; Kempenaars, M.; Bolzonella, T.; Rachlew, E.

    2005-01-01

    Plasma equilibria before and after ELMs in JET are investigated. ELMs could be associated with fragile equilibria and separatrix instabilities: previously closed field lines would open up, releasing plasma current and leading to the formation of a new, smaller separatrix. This model could explain experimental observations of sudden jumps and shifts in strike point positions. Novel instability mechanisms are discussed to explain the large transient jumps observed in the strike point position: positive X-point instability, due to positive toroidal current density at the X-point and diamagnetic instability, due to negative inboard toroidal current density. (author)

  9. Hybridization and introgression between the exotic Siberian elm, Ulmus pumila, and the native Field elm, U. minor, in Italy

    Science.gov (United States)

    In response to the first Dutch elm disease (DED) pandemic, Siberian elm, Ulmus pumila, was planted to replace the native elm, U. minor, in Italy. The potential for hybridization between these two species is high and repeated hybridization could result in the genetic swamping of the native species an...

  10. Dutch elm disease control: performance and costs

    Science.gov (United States)

    William N., Jr. Cannon; David P. Worley

    1976-01-01

    Municipal programs to suppress Dutch elm disease have had highly variable results. Performance as measured by tree mortality was unrelated to control strategies. Costs for control programs were 37 to 76 percent less than costs without control programs in the 15-year time-span of the study. Only those municipalities that conducted a high-performance program could be...

  11. ELMs and the H-mode Pedestal in NSTX

    Energy Technology Data Exchange (ETDEWEB)

    R. Maingi; S.A. Sabbagh; C.E. Bush; E.D. Fredrickson; J.E. Menard; D. Stutman; K. Tritz; M.G. Bell; R.E. Bell; J.A. Boedo; D.A. Gates; D.W. Johnson; R. Kaita; S.M. Kaye; H.W. Kugel; B.P. LeBlanc; D. Mueller; R. Raman; A.L. Roquemore; V.A. Soukhanovskii; T. Stevenson

    2004-07-16

    We report on the behavior of ELMs in NBI-heated H-mode plasmas in NSTX. It is observed that the size of Type I ELMs, characterized by the change in plasma energy, decreases with increasing density, as observed at conventional aspect ratio. It is also observed that the Type I ELM size decreases as the plasma equilibrium is shifted from a symmetric double-null toward a lower single-null configuration. Type III ELMs have also been observed in NSTX, as well as a high-performance regime with small ELMs which we designate Type V. These Type V ELMs are consistent with high bootstrap current operation and density approaching Greenwald scaling. The Type V ELMs are characterized by an intermittent n=1 MHD mode rotating counter to the plasma current. Without active pumping, the density rises continuously through the Type V phase. However, efficient in-vessel pumping should allow density control, based on particle containment time estimates.

  12. Different ELM regimes at ASDEX upgrade and their linear stability analysis

    Energy Technology Data Exchange (ETDEWEB)

    Burckhart, Andreas O.

    2013-12-16

    the theory, as the equilibrium becomes more stable against peeling-ballooning modes, the ELM frequency actually increases. Other scenarios in which peeling-ballooning modes are not thought to be the ELM trigger are also examined. In discharges featuring type-II and type-III ELMs the edge pressure gradient and current density are well below the threshold for peeling-ballooning instabilities, consistent with expectations. This indicates that other mechanisms must be present that prevent the kinetic profiles from building up. The behaviour of the analysed type-III ELMs is consistent with the hypothesis that they are driven by resistive interchange modes. The feasibility of triggering ELMs via frozen deuterium pellets is also examined in detail. In discharges performed when the walls of AUG were protected by carbon tiles, pellets triggered ELMs whenever they were injected into an H-mode plasma. In the tungsten-walled AUG, however, it is only possible to trigger ELMs after a specific lag time has elapsed since the previous ELM. This lag time can be significantly reduced, though not eliminated, when injecting nitrogen into the divertor. In the tungsten-walled AUG, with and without nitrogen, it is possible to trigger ELMs via pellets when the pedestal pressure gradient and the edge current density are 20% below the threshold for spontaneous ELMs. Since the ELM-induced collapse of the plasma edge pressure profile is strongest in the unseeded tungsten machine and the profile recovery is slower, the lag time for successful triggering is longer. Recent extrapolations of the ITER pedestal are also tested using the peeling-ballooning model. It is found that the predictions are very optimistic, but that stability could be achieved with temperatures and densities which are 30% lower than in the extrapolations. Some of the results presented in this thesis question the validity of the peeling-ballooning theory. In many of the presented cases, ELMs occur well below the threshold for

  13. Hyperparameterization of soil moisture statistical models for North America with Ensemble Learning Models (Elm)

    Science.gov (United States)

    Steinberg, P. D.; Brener, G.; Duffy, D.; Nearing, G. S.; Pelissier, C.

    2017-12-01

    Hyperparameterization, of statistical models, i.e. automated model scoring and selection, such as evolutionary algorithms, grid searches, and randomized searches, can improve forecast model skill by reducing errors associated with model parameterization, model structure, and statistical properties of training data. Ensemble Learning Models (Elm), and the related Earthio package, provide a flexible interface for automating the selection of parameters and model structure for machine learning models common in climate science and land cover classification, offering convenient tools for loading NetCDF, HDF, Grib, or GeoTiff files, decomposition methods like PCA and manifold learning, and parallel training and prediction with unsupervised and supervised classification, clustering, and regression estimators. Continuum Analytics is using Elm to experiment with statistical soil moisture forecasting based on meteorological forcing data from NASA's North American Land Data Assimilation System (NLDAS). There Elm is using the NSGA-2 multiobjective optimization algorithm for optimizing statistical preprocessing of forcing data to improve goodness-of-fit for statistical models (i.e. feature engineering). This presentation will discuss Elm and its components, including dask (distributed task scheduling), xarray (data structures for n-dimensional arrays), and scikit-learn (statistical preprocessing, clustering, classification, regression), and it will show how NSGA-2 is being used for automate selection of soil moisture forecast statistical models for North America.

  14. Inter-ELM and ELM-free divertor heat flux broadening induced by EHO in NSTX

    Science.gov (United States)

    Gan, Kaifu; Ahn, Joon-Wook; Maingi, Rajesh; Gray, Travis; Zweben, Stewart; Fredrickson, Eric; Canal, Gustavo; Wirth, Brian

    2016-10-01

    Recent study on multi-machine database of inter-ELM divertor heat flux indicates that the midplane Scrape-off Layer power fall-off length for ITER is expected to be very narrow, 1mm, which will induce small plasma-wetted area (Awet) and high peak heat flux (qpeak) . In NSTX, edge harmonic oscillation (EHO) was observed during certain inter-ELM and ELM-free periods of H-mode operation. The EHO is observed to significantly increase Awet, by up to a factor of 3, and decrease qpeak accordingly. The Awet increases with the amplitude of EHO. Multiple peaks appeared in the heat flux profile in the presence of EHO. An EHO-induced filament around separatrix rotating in the counter-current direction was also observed by gas puff imaging diagnostic. The increase of Awet is suspected to be caused by the rotating current filaments; the toroidally rotating filaments could have changed the edge magnetic topology and broadened heat flux profile by strike points splitting. Experimental observation of the temperal evolution of multiple peaks in heat flux profile shows consistent trend with the toroidal rotation of EHO. Inter-ELM and ELM-free divertor heat flux broadening induced by EHO in NSTX.

  15. ELM induced divertor heat loads on TCV

    Czech Academy of Sciences Publication Activity Database

    Marki, J.; Pitts, R. A.; Horáček, Jan; Tskhakaya, D.; TCV, team.

    309-391, - (2009), s. 801-805 ISSN 0022-3115. [International Conference on Plasma-Surface Interactions in Controlled Fusion Devices/18th./. Toledo, 26.05.2008-30.5.2008] Institutional research plan: CEZ:AV0Z20430508 Keywords : Tokamak TCV * divertor heat load * ELM * EVOLUTION * JET Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.933, year: 2009 http://dx.doi.org/10.1016/j.jnucmat.2009.01.212

  16. Making Sense Out of Pulsating Pre-ELM and ELM White Dwarfs

    Science.gov (United States)

    Fontaine, G.; Istrate, A.; Gianninas, A.; Brassard, P.; Van Grootel, V.

    2017-03-01

    We present a unified view of pulsations in both pre-ELM and ELM white dwarfs within the framework of state-of-the-art binary evolution calculations that take into account the combined effects of diffusion and rotational mixing. We find that rotational mixing is able to maintain against settling a sufficient amount of helium in the envelope in order to fuel pulsations through He II-He III ionization on the pre-ELM branch of the evolutionary track in the spectroscopic HR diagram. By the time such a low-mass white dwarf enters the ZZ Ceti instability strip on the cooling branch, settling has taken over rotational mixing and produced a pure H envelope. Such a star then pulsates again, but, this time, as a DA white dwarf of the ZZ Ceti type.

  17. A Novel Improved ELM Algorithm for a Real Industrial Application

    OpenAIRE

    Hai-Gang Zhang; Sen Zhang; Yi-Xin Yin

    2014-01-01

    It is well known that the feedforward neural networks meet numbers of difficulties in the applications because of its slow learning speed. The extreme learning machine (ELM) is a new single hidden layer feedforward neural network method aiming at improving the training speed. Nowadays ELM algorithm has received wide application with its good generalization performance under fast learning speed. However, there are still several problems needed to be solved in ELM. In this paper, a new impro...

  18. Do mites phoretic on elm bark beetles contribute to the transmission of Dutch elm disease?

    Science.gov (United States)

    Moser, John C.; Konrad, Heino; Blomquist, Stacy R.; Kirisits, Thomas

    2010-02-01

    Dutch elm disease (DED) is a destructive vascular wilt disease of elm ( Ulmus) trees caused by the introduced Ascomycete fungus Ophiostoma novo-ulmi. In Europe, this DED pathogen is transmitted by elm bark beetles in the genus Scolytus. These insects carry phoretic mites to new, suitable habitats. The aim of this study was to record and quantify conidia and ascospores of O. novo-ulmi on phoretic mites on the three elm bark beetle species Scolytus multistriatus, Scolytus pygmaeus, and Scolytus scolytus. Spores of O. novo-ulmi were found on four of the ten mite species phoretic on Scolytus spp. These included Elattoma fraxini, Proctolaelaps scolyti, Pseudotarsonemoides eccoptogasteri, and Tarsonemus crassus. All four species had spores attached externally to their body surfaces. However, T. crassus carried most spores within its sporothecae, two paired pocket-like structures adapted for fungal transmission. Individuals of Pr. scolyti also had O. novo-ulmi conidia and ascospores frequently in their digestive system, where they may remain viable. While E. fraxini and P. eccoptogasteri rarely had spores attached to their bodies, large portions of Pr. scolyti and T. crassus carried significant numbers of conidia and/or ascospores of O. novo-ulmi. P. scolyti and T. crassus, which likely are fungivores, may thus contribute to the transmission of O. novo-ulmi, by increasing the spore loads of individual Scolytus beetles during their maturation feeding on twigs of healthy elm trees, enhancing the chance for successful infection with the pathogen. Only S. scolytus, which is the most efficient vector of O. novo-ulmi in Europe, carried high numbers of Pr. scolyti and T. crassus, in contrast to S. multistriatus and S. pygmaeus, which are known as less efficient vectors. The high efficiency of S. scolytus in spreading Dutch elm disease may be partly due to its association with these two mites and the hyperphoretic spores of O. novo-ulmi they carry.

  19. Gamma irradiating elm billets reduces their attractancy to the smaller elm bark beetle, Scolytus multistriatus (Marsham)

    International Nuclear Information System (INIS)

    French, J.R.J.; Robinson, P.J.

    1982-01-01

    Irradiating elm billets with gamma rays had a significant effect in reducing the attractancy of these billets to inflight adults of the smaller elm bark beetle Scolytus multistriatus (Marsham). The temperature at which the fresh billets were stored prior to the beetle exposure had little effect. Irradiated billets, irrespective of storage temperature, had significantly fewer holes than the freshly cut billets. There were significant differences associated with the location of the billets in the field, but these differences were smaller than those associated with irradiation. (orig.) [de

  20. Adaptive Online Sequential ELM for Concept Drift Tackling

    Science.gov (United States)

    Basaruddin, Chan

    2016-01-01

    A machine learning method needs to adapt to over time changes in the environment. Such changes are known as concept drift. In this paper, we propose concept drift tackling method as an enhancement of Online Sequential Extreme Learning Machine (OS-ELM) and Constructive Enhancement OS-ELM (CEOS-ELM) by adding adaptive capability for classification and regression problem. The scheme is named as adaptive OS-ELM (AOS-ELM). It is a single classifier scheme that works well to handle real drift, virtual drift, and hybrid drift. The AOS-ELM also works well for sudden drift and recurrent context change type. The scheme is a simple unified method implemented in simple lines of code. We evaluated AOS-ELM on regression and classification problem by using concept drift public data set (SEA and STAGGER) and other public data sets such as MNIST, USPS, and IDS. Experiments show that our method gives higher kappa value compared to the multiclassifier ELM ensemble. Even though AOS-ELM in practice does not need hidden nodes increase, we address some issues related to the increasing of the hidden nodes such as error condition and rank values. We propose taking the rank of the pseudoinverse matrix as an indicator parameter to detect “underfitting” condition. PMID:27594879

  1. Fast dynamics of Type I ELM and transport of ELM pulse in JT-60U

    International Nuclear Information System (INIS)

    Oyama, N.

    2002-01-01

    The mitigation of the large ELM heat load on the divertor target is one of the most important issues to be overcome on ITER. Since the ELM heat load strikes the divertor target not as a time-averaged load but as an instantaneous heat pulse, the evaluation of both ELM energy, and the time scale of the collapse and transport is very important. In JT-60U, the detailed dynamic behaviors of the collapse were measured using O-mode reflectometer. The duration of the collapse was within 0.35 ms and the lost pedestal density was recovered quickly within 0.5 ms. The collapse reached 10 cm inside the separatrix, which corresponds to twice the pedestal width of 5 cm. Dedicated edge density measurements on high- and low-field side revealed the poloidal asymmetry of the collapse of density pedestal for the first time. The measurement of SOL flow and heat load to the divertor target by using SOL Mach probe and IRTV showed that convective transport of the SOL plasma gave large contribution to the ELM heat deposition process. (author)

  2. Birds and Dutch elm disease control

    Science.gov (United States)

    DeWitt, J.B.

    1958-01-01

    Brief, factual review of information on effect of DDT and other insecticides on birds. One program for control of elm disease caused 22% decrease in number of adult birds and 56% mortality of nestlings. Quail fed 3 oz. of DDT per ton of food had 16% reduction in young hatched and 500% increase in defective chicks. Quail fed same dosage during winter and breeding seasons had 30% decrease in fertile eggs and 800% increase in defective chicks. More than 90% of their chicks died in first 6 weeks although fed no insecticide. Almost equally bad results came from feeding Pheasants diets with about 1 oz. DDT per ton. Other common insecticides (chlorinated hydrocarbons) also caused lowered chick survival and higher percentages of crippled chicks. From field data we know that 2 lbs. DDT/acre can affect birds and has even worse effects on cold-blooded animals. Efforts to control elm disease have left as much as 196 lbs. DDT/acre in top 3 inches of soil. Earthworms concentrate DDT in their tissues. Thus the treated areas can be traps for birds and other animals. What can be done? 1) In control of elm disease, use minimum effective amount of insecticide; mist blowers use less than sprayers. 2) Avoid applications during migration and nesting seasons. It has been reported that adequate control can be obtained with dormant sprays and that foliar applications may not be required. Tables of this paper show effects of DDT on reproduction of Quail, relative toxicity to quail of 8 insecticides, and amounts of 7 insecticides required to cause 40% or more decrease in Quail reproduction. These comparisons demonstrate that Aldrin, Endrin, and Dieldrin are 20 to 200 times as toxic as DDT and that Heptachlor and Chlordane are only slightly less toxic than Dieldrin. Methoxychlor and Strobane are less toxic to Quail than is DDT.

  3. Automated recognition system for ELM classification in JET

    International Nuclear Information System (INIS)

    Duro, N.; Dormido, R.; Vega, J.; Dormido-Canto, S.; Farias, G.; Sanchez, J.; Vargas, H.; Murari, A.

    2009-01-01

    Edge localized modes (ELMs) are instabilities occurring in the edge of H-mode plasmas. Considerable efforts are being devoted to understanding the physics behind this non-linear phenomenon. A first characterization of ELMs is usually their identification as type I or type III. An automated pattern recognition system has been developed in JET for off-line ELM recognition and classification. The empirical method presented in this paper analyzes each individual ELM instead of starting from a temporal segment containing many ELM bursts. The ELM recognition and isolation is carried out using three signals: Dα, line integrated electron density and stored diamagnetic energy. A reduced set of characteristics (such as diamagnetic energy drop, ELM period or Dα shape) has been extracted to build supervised and unsupervised learning systems for classification purposes. The former are based on support vector machines (SVM). The latter have been developed with hierarchical and K-means clustering methods. The success rate of the classification systems is about 98% for a database of almost 300 ELMs.

  4. ELM-Induced Plasma Wall Interactions in DIII-D

    International Nuclear Information System (INIS)

    Rudakov, D.L.; Boedo, J.A.; Yu, J.H.; Brooks, N.H.; Fenstermacher, M.E.; Groth, M.; Hollmann, E.M.; Lasnier, C.J.; McLean, A.G.; Moyer, R.A.; Stangeby, P.C.; Tynan, G.R.; Wampler, W.R.; Watkins, J.G.; West, W.P.; Wong, C.C.; Zeng, L.; Bastasz, R.J.; Buchenauer, D.; Whaley, J.

    2008-01-01

    Intense transient fluxes of particles and heat to the main chamber components induced by edge localized modes (ELMs) are of serious concern for ITER. In DIII-D, plasma interaction with the outboard chamber wall is studied using Langmuir probes and optical diagnostics including a fast framing camera. Camera data shows that ELMs feature helical filamentary structures localized at the low field side of the plasma and aligned with the local magnetic field. During the nonlinear phase of an ELM, multiple filaments are ejected from the plasma edge and propagate towards the outboard wall with velocities of 0.5-0.7 km/s. When reaching the wall, filaments result in 'hot spots'--regions of local intense plasma-material interaction (PMI) where the peak incident particle and heat fluxes are up to 2 orders of magnitude higher than those between ELMs. This interaction pattern has a complicated geometry and is neither toroidally nor poloidally symmetric. In low density/collisionality H-mode discharges, PMI at the outboard wall is almost entirely due to ELMs. In high density/collisionality discharges, contributions of ELMs and inter-ELM periods to PMI at the wall are comparable. A Midplane Material Evaluation Station (MiMES) has been recently installed in order to conduct in situ measurements of erosion/redeposition at the outboard chamber wall, including those caused by ELMs

  5. Automated recognition system for ELM classification in JET

    Energy Technology Data Exchange (ETDEWEB)

    Duro, N. [Dpto. de Informatica y Automatica - UNED, C/ Juan del Rosal 16, 28040 Madrid (Spain)], E-mail: nduro@dia.uned.es; Dormido, R. [Dpto. de Informatica y Automatica - UNED, C/ Juan del Rosal 16, 28040 Madrid (Spain); Vega, J. [Asociacion EURATOM/CIEMAT para Fusion, Avd. Complutense 22, 28040 Madrid (Spain); Dormido-Canto, S.; Farias, G.; Sanchez, J.; Vargas, H. [Dpto. de Informatica y Automatica - UNED, C/ Juan del Rosal 16, 28040 Madrid (Spain); Murari, A. [Consorzio RFX-Associazione EURATOM ENEA per la Fusione, I-35127 Padua (Italy)

    2009-06-15

    Edge localized modes (ELMs) are instabilities occurring in the edge of H-mode plasmas. Considerable efforts are being devoted to understanding the physics behind this non-linear phenomenon. A first characterization of ELMs is usually their identification as type I or type III. An automated pattern recognition system has been developed in JET for off-line ELM recognition and classification. The empirical method presented in this paper analyzes each individual ELM instead of starting from a temporal segment containing many ELM bursts. The ELM recognition and isolation is carried out using three signals: D{alpha}, line integrated electron density and stored diamagnetic energy. A reduced set of characteristics (such as diamagnetic energy drop, ELM period or D{alpha} shape) has been extracted to build supervised and unsupervised learning systems for classification purposes. The former are based on support vector machines (SVM). The latter have been developed with hierarchical and K-means clustering methods. The success rate of the classification systems is about 98% for a database of almost 300 ELMs.

  6. Genome size variation in elms (Ulmus spp.) and related genera

    Science.gov (United States)

    The elms (the genus Ulmus) are one of the most important tree crops for the $4.7-billion per year U.S. nursery industry. Utilization of these plants has been limited in recent decades by diseases introduced from the Old World, especially Dutch elm disease. Past research and breeding have been based ...

  7. Establishment patterns of water-elm at Catahoula Lake, Louisiana

    Science.gov (United States)

    Karen S. Doerr; Sanjeev Joshi; Richard F. Keim

    2015-01-01

    At Catahoula Lake in central Louisiana, an internationally important lake for water fowl, hydrologic alterations to the surrounding rivers and the lake itself have led to an expansion of water-elm (Planera aquatic J.F. Gmel.) into the lake bed. In this study, we used dendrochronology and aerial photography to quantify the expansion of water-elm in the lake and identify...

  8. Restoring ecosystem resilience to urban forests using Dutch elm disease-tolerant American elm trees

    Science.gov (United States)

    Charles E. Flower; Cornelia C. Pinchot; James M. Slavicek

    2017-01-01

    Urban forests contribute significantly to human health and environmental quality (Sanesi et al. 2011). As such, maintaining healthy urban forests resilient to pollution (atmospheric and soil), high temperatures, compacted soils, and poor drainage is critical. However, these forests have been hard hit by development, pests, and pathogens, consequently reshaping their...

  9. The early struggles of the fledgling American Academy of Neurology: resistance from the old guard of American neurology.

    Science.gov (United States)

    Louis, Elan D

    2013-01-01

    The American Neurological Association, established in 1874, was a small exclusive society comprising senior neurologists at a select number of north-eastern academic institutions. In 1948, an attempt was made to establish a second neurological society in the USA. The American Academy of Neurology was formed around a group of young neurologists who represented the country's Midwest and other regions. The American Academy of Neurology is now the larger of the two organizations, even though the American Academy of Neurology began as a small and politically vulnerable organization, arising in the shadow of the powerful and established American Neurological Association. How did the 75-year-old association react when a second, seemingly redundant, neurological association attempted to organize? This question has not been the focus of historical work, and the purpose of this study was to address this. To do so, the author studied the primary source materials in the American Academy of Neurology Historical Collection and the papers of Dr Henry Alsop Riley, an American neurologist, who was influential in both the American Neurological Association and American Academy of Neurology. On its formation, the American Academy of Neurology did not enter a vacuum. Indeed, the long-existing American Neurological Association actively resisted the new organization. There was reluctance to accept the new idea on a conceptual level, a formal attempt to hijack the new organization and discussions about punitive actions against its founder, while at the same time an attempt to bring him into the American Neurological Association leadership. Although the American Neurological Association attempted to frame itself as the patrician 'upper chamber' of American neurology, the American Academy of Neurology leadership was ultimately savvier at political manoeuvring and use of government agencies and funding organizations. The struggle of the American Academy of Neurology with the American

  10. Mildew-resistant mutants induced in North American two- and six-rowed malting barley cultivars

    DEFF Research Database (Denmark)

    Molina-Cano, J.L.; Simiand, J.P.; Sopena, A.

    2003-01-01

    Mildew-resistant mutants were induced with sodium azide in three North American malting barley cultivars, two in the six-rowed Ursula (URS1 and URS2), one in the six-rowed Gertrud (GER1), and one in the two-rowed Prudentia (PRU1). Two of the mutants, URS1 and PRU1, showed complete resistance...

  11. Validation of the model for ELM suppression with 3D magnetic fields using low torque ITER baseline scenario discharges in DIII-D

    Science.gov (United States)

    Moyer, R. A.; Paz-Soldan, C.; Nazikian, R.; Orlov, D. M.; Ferraro, N. M.; Grierson, B. A.; Knölker, M.; Lyons, B. C.; McKee, G. R.; Osborne, T. H.; Rhodes, T. L.; Meneghini, O.; Smith, S.; Evans, T. E.; Fenstermacher, M. E.; Groebner, R. J.; Hanson, J. M.; La Haye, R. J.; Luce, T. C.; Mordijck, S.; Solomon, W. M.; Turco, F.; Yan, Z.; Zeng, L.; DIII-D Team

    2017-10-01

    Experiments have been executed in the DIII-D tokamak to extend suppression of Edge Localized Modes (ELMs) with Resonant Magnetic Perturbations (RMPs) to ITER-relevant levels of beam torque. The results support the hypothesis for RMP ELM suppression based on transition from an ideal screened response to a tearing response at a resonant surface that prevents expansion of the pedestal to an unstable width [Snyder et al., Nucl. Fusion 51, 103016 (2011) and Wade et al., Nucl. Fusion 55, 023002 (2015)]. In ITER baseline plasmas with I/aB = 1.4 and pedestal ν * ˜ 0.15, ELMs are readily suppressed with co- I p neutral beam injection. However, reducing the beam torque from 5 Nm to ≤ 3.5 Nm results in loss of ELM suppression and a shift in the zero-crossing of the electron perpendicular rotation ω ⊥ e ˜ 0 deeper into the plasma. The change in radius of ω ⊥ e ˜ 0 is due primarily to changes to the electron diamagnetic rotation frequency ωe * . Linear plasma response modeling with the resistive MHD code m3d-c1 indicates that the tearing response location tracks the inward shift in ω ⊥ e ˜ 0. At pedestal ν * ˜ 1, ELM suppression is also lost when the beam torque is reduced, but the ω ⊥ e change is dominated by collapse of the toroidal rotation v T . The hypothesis predicts that it should be possible to obtain ELM suppression at reduced beam torque by also reducing the height and width of the ωe * profile. This prediction has been confirmed experimentally with RMP ELM suppression at 0 Nm of beam torque and plasma normalized pressure β N ˜ 0.7. This opens the possibility of accessing ELM suppression in low torque ITER baseline plasmas by establishing suppression at low beta and then increasing beta while relying on the strong RMP-island coupling to maintain suppression.

  12. First observation of ELM pacing with vertical jogs in a spherical torus

    Science.gov (United States)

    Gerhardt, S. P.; Ahn, J.-W.; Canik, J. M.; Maingi, R.; Bell, R.; Gates, D.; Goldston, R.; Hawryluk, R.; Le Blanc, B. P.; Menard, J.; Sontag, A. C.; Sabbagh, S.; Tritz, K.

    2010-06-01

    Experiments in a number of conventional aspect ratio tokamaks have been successful in pacing edge localized modes (ELMs) by rapid vertical jogging of the plasma. This paper demonstrates the first pacing of ELMs in a spherical torus plasma. Applied 30 Hz vertical jogs synchronized the ELMs with the upward motion of the plasma. 45 Hz jogs also lead to an increase in the ELM frequency, though the synchronization of the ELMs and jogs was unclear. A reduction in the ELM energy was observed at the higher driven ELM frequencies.

  13. Localised Microwave Bursts During ELMs on MAST

    Directory of Open Access Journals (Sweden)

    Freethy Simon

    2015-01-01

    Full Text Available Bursts of microwave emission are observed during ELM events on the Mega Ampère Spherical Tokamak. In agreement with observations on other machines, these bursts are up to 3 orders of magnitude more intense than the thermal background, but are electron cyclotron in nature. The peak in microwave emission is ~20μ before the peak in midplane Dα emission. Using the Synthetic Aperture Microwave Imaging radiometer, we are able to demonstrate that these bursts are often highly spatially localised and preferentially occur at the tokamak midplane. It is hypothesised that the localisation is a result of Doppler resonance broadening for electron Bernstein waves and the high perpendicular electron energies could be the result of pitch angle scattering in high collisionality regions of the plasma.

  14. Manufacture of mineral-insulated conductor for ITER prototype ELM and VS coil

    International Nuclear Information System (INIS)

    Long, Feng; Wu, Yu; Jin, Huan; Yu, Min; Han, Qiyang; Ling, Feng; Kalish, Michael

    2015-01-01

    Highlights: • Compaction method is successfully developed for MIC manufacture. • Manufactured MICs show well controlled outer diameter and good electrical properties. • Insulation resistance of all the MICs is higher than 100 GΩ@DC 2500 V. - Abstract: An ITER Organization (IO) Task Agreement (TA) “Final Design and Prototyping of the ITER In-Vessel Coils (IVC) and Feeders” is almost finished by Institute of Plasma Physics, Chinese Academy of Sciences (ASIPP). ITER IVCs consist of edge-localized mode (ELM) and vertical stabilization (VS) coils. One prototype Mid-ELM coil complete with 19 brackets brazed with the conductors and one prototype 120° section of upper VS coil with structural components brazed to the conductors have been fabricated. Compaction method is developed successfully for the mineral-insulated conductor (MIC) manufacture. Approximate 110 m Inconel 625 jacket MICs for Mid-ELM prototype coil and 80 m stainless steel 316L jacket MICs for VS prototype coil were manufactured. Most of the copper tubes used for the MICs fabrication failed the ultrasonic testing (UT), but the jacket tubes have good passing rate. Manufacture processes and inspection for the MICs are presented in this paper

  15. Ex situ conservation of genetic resources of field elm (Ulmus minor Mill and European white elm (Ulmus laevis Pall

    Directory of Open Access Journals (Sweden)

    Aleksić Jelena

    2004-01-01

    Full Text Available Principles of the conservation of genetic resources of elms (Ulmus spp do not differ fundamentally from the general principles accepted for the conservation of genetic resources of other common Noble Hardwoods. Efficient conservation can best be achieved through appropriate combination of in situ and ex situ methods, which have distinct advantages. Besides that, ex situ conservation is employed when emergency measures are needed for rare endangered populations and when populations are too small to be managed in situ (e.g. risks of genetic drift and inbreeding. The aim of our research is ex situ conservation of genetic resources of field elm {Ulmus minor Mill and European white elm (Ulmus laevis Pall through establishment of field genebanks. Sampling was conducted in one population of field elm and one population of white elm. Plant material (buds from 8 trees of field elm and 10 trees of white elm was used for in vitro production of clones. Obtained clones will be used for establishment of field genebanks on the experimental estate of the Institute of Lowland Forestry and Environment.

  16. Ideological Barriers to American Sign Language: Unpacking Linguistic Resistance

    Science.gov (United States)

    Reagan, Timothy

    2011-01-01

    This article addresses the debate about the status of American Sign Language (ASL) as an example of ideological beliefs that impact linguistic judgments and policies. It also discusses the major challenges to the status of ASL with respect to formal legislative recognition, its utility as a medium of instruction, and its status as a legitimate…

  17. e-Learning Management System (eLMS) -

    Data.gov (United States)

    Department of Transportation — DOT's electronic Learning Management System (eLMS) is a state-of-the-art web-based system that meets the needs of training administrators, learners, and managers and...

  18. Pheromone Chemistry of the Smaller European Elm Bark Beetle.

    Science.gov (United States)

    Beck, Keith

    1978-01-01

    Discusses the aggregation pheromone of the smaller European elm bark beetle, Scolytus multistriatus (Marsham), with emphasis on information that could be used in the classroom as a practical application of organic chemistry. (Author/GA)

  19. ELM pacing and the ITER operating window: mutual constraints

    Science.gov (United States)

    Pacher, G. W.; Pacher, H. D.; Kukushkin, A. S.; Pitts, R. A.

    2011-08-01

    On ITER, one of the methods foreseen to reduce the energy loading due to edge localized modes (ELMs) on the divertor targets is the use of pellet injection to control the ELM frequency and amplitude of the energy losses at each ELM. However, the use of such pellet pacing introduces additional fuel throughput. This may constrict the burning plasma operating window through its influence on divertor plasma detachment, thus reducing the attainable alpha power. Consistent modelling of core, scrape-off layer, and divertor is used to document this effect. The result is a determination of the maximum attainable alpha power at the nominal pumping speed as a function of pacing pellet size and the maximum allowable pellet size as a function of ELM loss power fraction for which the reference operating window is not reduced.

  20. The modern state of elms (Ulmus L., Ulmaceae in arboretum of Peter the Great Botanic Garden under conditions of epiphytoty of the Dutch elm disease

    Directory of Open Access Journals (Sweden)

    Firsov Gennadii

    2017-12-01

    Full Text Available The dying of elms (Ulmus L. at Peter the Great Botanic Garden of the Komarov Botanical Institute RAS in Saint-Petersburg has been observed since the beginning of the 1990’s, soon after the considerable St.-Petersburg climate warming in 1989. During the period from 1981 (the year of the last total inventory of the Botanic Garden to 2015 three hundred and eighty five trees died, were cut down and removed. They belonged to 12 Ulmus biological and cultivars species: U. laevis – 317 (11 trees are still alive, but all of them are infected, stem dried out from 25 to 70%, U. glabra – 40 (died completely in 2013; U. glabra ‘Camperdownii’ – 6 (died completely in 2014; U. minor – 6 (died completely in 2011; U. аmericana – 4 (died in 2007; U. × hollandica ‘Wredei’ – 3 (died in 2013; U. macrocarpa – 2 (died in 2006; U. pumila ‘Argenteo-variegata’ – 2 (died in 2007; U. japonica – 2 (1 tree is still alive; U. laciniata – 1 (died in 2015; U. parvifolia – 1 (3 trees are still alive; U. pumila – 1 (5 trees are still alive. The most severe dying began after abnormally warm winter 2006/07, the largest amount died in 2013. The most resistant to Dutch elm disease taxa were U. parvifolia and U. pumila. Further research is needed for other two taxa (U. × arbuscula and U. japonica. Selection of elms for resistance to Dutch elm disease seems to be possible. Frost damaging of many exotic tree species in St.-Petersburg has been considerably diminished because of climate warming during the previuos decades. However, introduction of some species is became limited by new negative factors, especially biotic ones (new plant diseases and pests. The future arboreal species assortment for parks and gardens of St.-Petersburg and surrounding settlements should be considerably revised in respect to this climate change.

  1. Seasonal changes in wood formation of Ulmus pumila and U. minor and its relation with Dutch elm disease.

    Science.gov (United States)

    Solla, A; Martín, J A; Corral, P; Gil, L

    2005-06-01

    Elms containing narrow and scattered vessels have been reported to be more resistant to Ophiostoma novo-ulmi (Dutch elm disease pathogen) than elms with large and contiguous vessels. However, recent measurements in Ulmus pumila and U. minor showed a contrary trend. The pin method was applied to 4-yr-old branches of eight clones planted in Madrid. During 2002, radial growth increments and vessel diameters were measured monthly, and beetle trapping was undertaken weekly. U. minor formed larger vessels at the beginning of the season, coinciding with a peak of captured beetles, but, up to June 15, vessels were larger for U. pumila. The number of vessels per group, the transversal area per vessel group, and the mean theoretical hydraulic conductances were significantly higher for U. minor on most dates. Researchers should take into consideration the seasonal changes in vessel size. The results highlight that seasonal variation of vessel diameters and hydraulic parameters, in combination with beetle abundance, are the main factors that could explain the different susceptibility of both elm species to O. novo-ulmi.

  2. ELM Mitigation Using Pellet Injection and Plans for ITER

    Science.gov (United States)

    Baylor, L. R.; Commaux, N.; Meitner, S. J.; Rassmussen, D. A.; Lasnier, C. J.; Fenstermacher, M. E.; Allen, S. L.; Leonard, A. W.; Osborne, T. H.; Parks, P. B.; Moyer, R. A.; Loarte, A.; Huijsmans, G.; Maruyama, S.

    2013-10-01

    D2 pellet injection has been used on the DIII-D tokamak to demonstrate the triggering of edge localized modes (ELMs) at a 12x higher rate with much smaller intensity than natural ELMs. The triggering of small ELMs by pellet injection has been proposed as a method to prevent large ELMs that can erode the ITER plasma facing components. The demonstration was made by injecting slow (pellets at up to 60 Hz from the low field side in an ITER similar plasma with 5 Hz natural ELMs resulting in total and peak divertor heat flux reduction by more than 90%. New experiments with smaller pellets and higher rep rates are underway. Determining the minimum size perturbation and the resulting heat flux pattern in the divertor are the subject of these new experiments. The implications of these results for pellet ELM mitigation in ITER and the design of the pellet injection system for ITER will be discussed. Supported by the US DOE under DE-AC05-00OR22725, DE-AC52-07NA27344, DE-FC02-04ER54698, & DE-FG02-07ER54917.

  3. Distinguishing deterministic and noise components in ELM time series

    International Nuclear Information System (INIS)

    Zvejnieks, G.; Kuzovkov, V.N

    2004-01-01

    Full text: One of the main problems in the preliminary data analysis is distinguishing the deterministic and noise components in the experimental signals. For example, in plasma physics the question arises analyzing edge localized modes (ELMs): is observed ELM behavior governed by a complicate deterministic chaos or just by random processes. We have developed methodology based on financial engineering principles, which allows us to distinguish deterministic and noise components. We extended the linear auto regression method (AR) by including the non-linearity (NAR method). As a starting point we have chosen the nonlinearity in the polynomial form, however, the NAR method can be extended to any other type of non-linear functions. The best polynomial model describing the experimental ELM time series was selected using Bayesian Information Criterion (BIC). With this method we have analyzed type I ELM behavior in a subset of ASDEX Upgrade shots. Obtained results indicate that a linear AR model can describe the ELM behavior. In turn, it means that type I ELM behavior is of a relaxation or random type

  4. Fire resistance in American heavy timber construction history and preservation

    CERN Document Server

    Heitz, Jesse

    2016-01-01

    This volume presents a history of heavy timber construction (HTC) in the United States, chronicling nearly two centuries of building history, from inception to a detailed evaluation of one of the best surviving examples of the type, with an emphasis on fire resistance. The book does not limit itself in scope to serving only as a common history. Rather, it provides critical analysis of HTC in terms of construction methods, design, technical specifications, and historical performance under fire conditions. As such, this book provides readers with a truly comprehensive understanding and exploration of heavy timber construction in the United States and its performance under fire conditions.

  5. Electromagnetic ELM and inter-ELM filaments detected in the COMPASS Scrape-Off Layer.

    Czech Academy of Sciences Publication Activity Database

    Spolaore, M.; Kovařík, Karel; Stöckel, Jan; Adámek, Jiří; Dejarnac, Renaud; Ďuran, Ivan; Komm, Michael; Markovič, Tomáš; Martines, E.; Pánek, Radomír; Seidl, Jakub; Vianello, N.

    2017-01-01

    Roč. 12, August (2017), s. 844-851 ISSN 2352-1791. [PSI 2016 - 22nd International Conference on Plasma Surface Interactions in Controlled Fusion Devices/22./. Roma, 30.05.2016-03.06.2016] R&D Projects: GA MŠk(CZ) 8D15001; GA MŠk(CZ) LM2015045 EU Projects: European Commission(XE) 633053 - EUROfusion Institutional support: RVO:61389021 Keywords : Electromagnetic filaments * ELMs * Scrape-Off Layer * Magnetic fluctuations * Current density Subject RIV: BL - Plasma and Gas Discharge Physics OBOR OECD: Fluids and plasma physics (including surface physics) http://www. science direct.com/ science /article/pii/S2352179116301934

  6. Analysis of ELM stability with extended MHD models in JET, JT-60U and future JT-60SA tokamak plasmas

    Science.gov (United States)

    Aiba, N.; Pamela, S.; Honda, M.; Urano, H.; Giroud, C.; Delabie, E.; Frassinetti, L.; Lupelli, I.; Hayashi, N.; Huijsmans, G.; JET Contributors, the; Research Unit, JT-60SA

    2018-01-01

    The stability with respect to a peeling-ballooning mode (PBM) was investigated numerically with extended MHD simulation codes in JET, JT-60U and future JT-60SA plasmas. The MINERVA-DI code was used to analyze the linear stability, including the effects of rotation and ion diamagnetic drift ({ω }* {{i}}), in JET-ILW and JT-60SA plasmas, and the JOREK code was used to simulate nonlinear dynamics with rotation, viscosity and resistivity in JT-60U plasmas. It was validated quantitatively that the ELM trigger condition in JET-ILW plasmas can be reasonably explained by taking into account both the rotation and {ω }* {{i}} effects in the numerical analysis. When deuterium poloidal rotation is evaluated based on neoclassical theory, an increase in the effective charge of plasma destabilizes the PBM because of an acceleration of rotation and a decrease in {ω }* {{i}}. The difference in the amount of ELM energy loss in JT-60U plasmas rotating in opposite directions was reproduced qualitatively with JOREK. By comparing the ELM affected areas with linear eigenfunctions, it was confirmed that the difference in the linear stability property, due not to the rotation direction but to the plasma density profile, is thought to be responsible for changing the ELM energy loss just after the ELM crash. A predictive study to determine the pedestal profiles in JT-60SA was performed by updating the EPED1 model to include the rotation and {ω }* {{i}} effects in the PBM stability analysis. It was shown that the plasma rotation predicted with the neoclassical toroidal viscosity degrades the pedestal performance by about 10% by destabilizing the PBM, but the pressure pedestal height will be high enough to achieve the target parameters required for the ITER-like shape inductive scenario in JT-60SA.

  7. Recrystallization and grain growth induced by ELMs-like transient heat loads in deformed tungsten samples.

    Science.gov (United States)

    Suslova, A; El-Atwani, O; Sagapuram, D; Harilal, S S; Hassanein, A

    2014-11-04

    Tungsten has been chosen as the main candidate for plasma facing components (PFCs) due to its superior properties under extreme operating conditions in future nuclear fusion reactors such as ITER. One of the serious issues for PFCs is the high heat load during transient events such as ELMs and disruption in the reactor. Recrystallization and grain size growth in PFC materials caused by transients are undesirable changes in the material, since the isotropic microstructure developed after recrystallization exhibits a higher ductile-to-brittle transition temperature which increases with the grain size, a lower thermal shock fatigue resistance, a lower mechanical strength, and an increased surface roughening. The current work was focused on careful determination of the threshold parameters for surface recrystallization, grain growth rate, and thermal shock fatigue resistance under ELM-like transient heat events. Transient heat loads were simulated using long pulse laser beams for two different grades of ultrafine-grained tungsten. It was observed that cold rolled tungsten demonstrated better power handling capabilities and higher thermal stress fatigue resistance compared to severely deformed tungsten. Higher recrystallization threshold, slower grain growth, and lower degree of surface roughening were observed in the cold rolled tungsten.

  8. Strategy and Resistance: How Native American Students Engage in Accommodation in Mainstream Schools

    Science.gov (United States)

    Masta, Stephanie

    2018-01-01

    This article explores the experiences of a group of Native American 8th graders who attend a mainstream school and how they engage in accommodation as an act of agency and resistance to protect and maintain their identities in their school environment. By using tribal critical race theory to examine these experiences, this study raises important…

  9. Association between haptoglobin gene and insulin resistance in Arab-Americans.

    Science.gov (United States)

    Burghardt, Kyle J; Masri, Dana El; Dass, Sabrina E; Shikwana, Sara S; Jaber, Linda A

    2017-11-01

    To analyze associations between variation in the HP gene and lipid and glucose-related measures in Arab-Americans. Secondary analyses were performed based on sex. Genomic DNA was extracted from samples obtained from a previous epidemiological study of diabetes in Arab-Americans. The HP 1 and 2 alleles were analyzed by polymerase chain reaction and gel electrophoresis. Associations were analyzed by linear regression. Associations were identified between the heterozygous haptoglobin 2-1 genotype and insulin resistance, fasting insulin and fasting c-peptide. The effect of sex did not remain significant after adjustment for relevant variables. HP genetic variation may have utility as a biomarker of insulin resistance and diabetes risk in Arab-Americans, however, future prospective studies are needed.

  10. Glyphosate-resistant weeds of South American cropping systems: an overview.

    Science.gov (United States)

    Vila-Aiub, Martin M; Vidal, Ribas A; Balbi, Maria C; Gundel, Pedro E; Trucco, Frederico; Ghersa, Claudio M

    2008-04-01

    Herbicide resistance is an evolutionary event resulting from intense herbicide selection over genetically diverse weed populations. In South America, orchard, cereal and legume cropping systems show a strong dependence on glyphosate to control weeds. The goal of this report is to review the current knowledge on cases of evolved glyphosate-resistant weeds in South American agriculture. The first reports of glyphosate resistance include populations of highly diverse taxa (Lolium multiflorum Lam., Conyza bonariensis L., C. canadensis L.). In all instances, resistance evolution followed intense glyphosate use in fruit fields of Chile and Brazil. In fruit orchards from Colombia, Parthenium hysterophorus L. has shown the ability to withstand high glyphosate rates. The recent appearance of glyphosate-resistant Sorghum halepense L. and Euphorbia heterophylla L. in glyphosate-resistant soybean fields of Argentina and Brazil, respectively, is of major concern. The evolution of glyphosate resistance has clearly taken place in those agroecosystems where glyphosate exerts a strong and continuous selection pressure on weeds. The massive adoption of no-till practices together with the utilization of glyphosate-resistant soybean crops are factors encouraging increase in glyphosate use. This phenomenon has been more evident in Argentina and Brazil. The exclusive reliance on glyphosate as the main tool for weed management results in agroecosystems biologically more prone to glyphosate resistance evolution. Copyright (c) 2007 Society of Chemical Industry.

  11. Investigation of dynamics of ELM crashes and their mitigation techniques

    Energy Technology Data Exchange (ETDEWEB)

    Pankin, Alexei Y. [Tech-X Corporation, Boulder, CO (United States)

    2015-08-14

    The accurate prediction of H-mode pedestal dynamics is critical for planning experiments in existing tokamaks and in the design of future tokamaks such as ITER and DEMO. The main objective of the proposed research is to advance the understanding of the physics of H-mode pedestal. Through advances in coupled kinetic-MHD simulations, a new model for H-mode pedestal and ELM crashes as well as an improved model for the bootstrap current will be developed. ELMmitigation techniques will also be investigated. The proposed research will help design efficient confinement scenarios and reduce transient heat loads on the divertor and plasma facing components. During the last two years, the principal investigator (PI) of this proposal actively participated in physics studies related to the DOE Joint Research Targets. These studies include the modeling of divertor heat load in the DIII-D, Alcator C-Mod, and NSTX tokamaks in 2010, and the modeling of H-mode pedestal structure in the DIII-D tokamak in 2011. It is proposed that this close collaboration with experimentalists from major US tokamaks continue during the next funding period. Verification and validation will be a strong component of the proposed research. During the course of the project, advances will be made in the following areas; Dynamics of the H-mode pedestal buildup and recovery after ELM crashes – The effects of neutral fueling, particle and thermal pinches will be explored; Dynamics of ELM crashes in realistic tokamak geometries – Heat loads associated with ELM crashes will be validated against experimental measurements. An improved model for ELM crashes will be developed; ELM mitigation – The effect of resonant magnetic perturbations on ELMs stability and their evolution will be investigated; Development of a new bootstrap current model – A reduced model for will be developed through careful verification of existing models for bootstrap current against first-principle kinetic neoclassical simulations

  12. ELM: an Algorithm to Estimate the Alpha Abundance from Low-resolution Spectra

    Science.gov (United States)

    Bu, Yude; Zhao, Gang; Pan, Jingchang; Bharat Kumar, Yerra

    2016-01-01

    We have investigated a novel methodology using the extreme learning machine (ELM) algorithm to determine the α abundance of stars. Applying two methods based on the ELM algorithm—ELM+spectra and ELM+Lick indices—to the stellar spectra from the ELODIE database, we measured the α abundance with a precision better than 0.065 dex. By applying these two methods to the spectra with different signal-to-noise ratios (S/Ns) and different resolutions, we found that ELM+spectra is more robust against degraded resolution and ELM+Lick indices is more robust against variation in S/N. To further validate the performance of ELM, we applied ELM+spectra and ELM+Lick indices to SDSS spectra and estimated α abundances with a precision around 0.10 dex, which is comparable to the results given by the SEGUE Stellar Parameter Pipeline. We further applied ELM to the spectra of stars in Galactic globular clusters (M15, M13, M71) and open clusters (NGC 2420, M67, NGC 6791), and results show good agreement with previous studies (within 1σ). A comparison of the ELM with other widely used methods including support vector machine, Gaussian process regression, artificial neural networks, and linear least-squares regression shows that ELM is efficient with computational resources and more accurate than other methods.

  13. ELM: AN ALGORITHM TO ESTIMATE THE ALPHA ABUNDANCE FROM LOW-RESOLUTION SPECTRA

    International Nuclear Information System (INIS)

    Bu, Yude; Zhao, Gang; Kumar, Yerra Bharat; Pan, Jingchang

    2016-01-01

    We have investigated a novel methodology using the extreme learning machine (ELM) algorithm to determine the α abundance of stars. Applying two methods based on the ELM algorithm—ELM+spectra and ELM+Lick indices—to the stellar spectra from the ELODIE database, we measured the α abundance with a precision better than 0.065 dex. By applying these two methods to the spectra with different signal-to-noise ratios (S/Ns) and different resolutions, we found that ELM+spectra is more robust against degraded resolution and ELM+Lick indices is more robust against variation in S/N. To further validate the performance of ELM, we applied ELM+spectra and ELM+Lick indices to SDSS spectra and estimated α abundances with a precision around 0.10 dex, which is comparable to the results given by the SEGUE Stellar Parameter Pipeline. We further applied ELM to the spectra of stars in Galactic globular clusters (M15, M13, M71) and open clusters (NGC 2420, M67, NGC 6791), and results show good agreement with previous studies (within 1σ). A comparison of the ELM with other widely used methods including support vector machine, Gaussian process regression, artificial neural networks, and linear least-squares regression shows that ELM is efficient with computational resources and more accurate than other methods

  14. ELM: AN ALGORITHM TO ESTIMATE THE ALPHA ABUNDANCE FROM LOW-RESOLUTION SPECTRA

    Energy Technology Data Exchange (ETDEWEB)

    Bu, Yude [School of Mathematics and Statistics, Shandong University, Weihai, 264209, Shandong (China); Zhao, Gang; Kumar, Yerra Bharat [Key Laboratory for Optical Astronomy, National Astronomical Observatories, Chinese Academy of Sciences, Beijing, 100012 (China); Pan, Jingchang, E-mail: ydbu@bao.ac.cn, E-mail: gzhao@nao.cas.cn [School of Mechanical, Electrical and Information Engineering, Shandong University, Weihai, 264209, Shandong (China)

    2016-01-20

    We have investigated a novel methodology using the extreme learning machine (ELM) algorithm to determine the α abundance of stars. Applying two methods based on the ELM algorithm—ELM+spectra and ELM+Lick indices—to the stellar spectra from the ELODIE database, we measured the α abundance with a precision better than 0.065 dex. By applying these two methods to the spectra with different signal-to-noise ratios (S/Ns) and different resolutions, we found that ELM+spectra is more robust against degraded resolution and ELM+Lick indices is more robust against variation in S/N. To further validate the performance of ELM, we applied ELM+spectra and ELM+Lick indices to SDSS spectra and estimated α abundances with a precision around 0.10 dex, which is comparable to the results given by the SEGUE Stellar Parameter Pipeline. We further applied ELM to the spectra of stars in Galactic globular clusters (M15, M13, M71) and open clusters (NGC 2420, M67, NGC 6791), and results show good agreement with previous studies (within 1σ). A comparison of the ELM with other widely used methods including support vector machine, Gaussian process regression, artificial neural networks, and linear least-squares regression shows that ELM is efficient with computational resources and more accurate than other methods.

  15. ELM-induced transient tungsten melting in the JET divertor

    Science.gov (United States)

    Coenen, J. W.; Arnoux, G.; Bazylev, B.; Matthews, G. F.; Autricque, A.; Balboa, I.; Clever, M.; Dejarnac, R.; Coffey, I.; Corre, Y.; Devaux, S.; Frassinetti, L.; Gauthier, E.; Horacek, J.; Jachmich, S.; Komm, M.; Knaup, M.; Krieger, K.; Marsen, S.; Meigs, A.; Mertens, Ph.; Pitts, R. A.; Puetterich, T.; Rack, M.; Stamp, M.; Sergienko, G.; Tamain, P.; Thompson, V.; Contributors, JET-EFDA

    2015-02-01

    The original goals of the JET ITER-like wall included the study of the impact of an all W divertor on plasma operation (Coenen et al 2013 Nucl. Fusion 53 073043) and fuel retention (Brezinsek et al 2013 Nucl. Fusion 53 083023). ITER has recently decided to install a full-tungsten (W) divertor from the start of operations. One of the key inputs required in support of this decision was the study of the possibility of W melting and melt splashing during transients. Damage of this type can lead to modifications of surface topology which could lead to higher disruption frequency or compromise subsequent plasma operation. Although every effort will be made to avoid leading edges, ITER plasma stored energies are sufficient that transients can drive shallow melting on the top surfaces of components. JET is able to produce ELMs large enough to allow access to transient melting in a regime of relevance to ITER. Transient W melt experiments were performed in JET using a dedicated divertor module and a sequence of IP = 3.0 MA/BT = 2.9 T H-mode pulses with an input power of PIN = 23 MW, a stored energy of ˜6 MJ and regular type I ELMs at ΔWELM = 0.3 MJ and fELM ˜ 30 Hz. By moving the outer strike point onto a dedicated leading edge in the W divertor the base temperature was raised within ˜1 s to a level allowing transient, ELM-driven melting during the subsequent 0.5 s. Such ELMs (δW ˜ 300 kJ per ELM) are comparable to mitigated ELMs expected in ITER (Pitts et al 2011 J. Nucl. Mater. 415 (Suppl.) S957-64). Although significant material losses in terms of ejections into the plasma were not observed, there is indirect evidence that some small droplets (˜80 µm) were released. Almost 1 mm (˜6 mm3) of W was moved by ˜150 ELMs within 7 subsequent discharges. The impact on the main plasma parameters was minor and no disruptions occurred. The W-melt gradually moved along the leading edge towards the high-field side, driven by j × B forces. The evaporation rate determined

  16. A Survey and Analysis of the American Public's Perceptions and Knowledge About Antibiotic Resistance.

    Science.gov (United States)

    Carter, Rebecca R; Sun, Jiayang; Jump, Robin L P

    2016-09-01

    Background.  Little is known about the American public's perceptions or knowledge about antibiotic-resistant bacteria or antibiotic misuse. We hypothesized that although many people recognize antibiotic resistance as a problem, they may not understand the relationship between antibiotic consumption and selection of resistant bacteria. Methods.  We developed and tested a survey asking respondents about their perceptions and knowledge regarding appropriate antibiotic use. Respondents were recruited with the Amazon Mechanical Turk crowdsourcing platform. The survey, carefully designed to assess a crowd-sourced population, asked respondents to explain "antibiotic resistance" in their own words. Subsequent questions were multiple choice. Results.  Of 215 respondents, the vast majority agreed that inappropriate antibiotic use contributes to antibiotic resistance (92%), whereas a notable proportion (70%) responded neutrally or disagreed with the statement that antibiotic resistance is a problem. Over 40% of respondents indicated that antibiotics were the best choice to treat a fever or a runny nose and sore throat. Major themes from the free-text responses included that antibiotic resistance develops by bacteria, or by the infection, or the body (ie, an immune response). Minor themes included antibiotic overuse and antibiotic resistance caused by bacterial adaptation or an immune response. Conclusions.  Our findings indicate that the public is aware that antibiotic misuse contributes to antibiotic resistance, but many do not consider it to be an important problem. The free-text responses suggest specific educational targets, including the difference between an immune response and bacterial adaptation, to increase awareness and understanding of antibiotic resistance.

  17. Role of phytohormones in organogenic ability of elm multiplicated shoots

    Czech Academy of Sciences Publication Activity Database

    Malá, J.; Gaudinová, Alena; Dobrev, Petre; Eder, Josef; Cvikrová, Milena

    2006-01-01

    Roč. 50, č. 1 (2006), s. 8-14 ISSN 0006-3134 Institutional research plan: CEZ:AV0Z5038910; CEZ:AV0Z50380511 Keywords : auxin * cytokinins * multiplication of elm Subject RIV: GK - Forestry Impact factor: 1.198, year: 2006

  18. Menyoal Elaboration Likelihood Model (ELM dan Teori Retorika

    Directory of Open Access Journals (Sweden)

    Yudi Perbawaningsih

    2012-06-01

    Full Text Available Abstract: Persuasion is a communication process to establish or change attitudes, which can be understood through theory of Rhetoric and theory of Elaboration Likelihood Model (ELM. This study elaborates these theories in a Public Lecture series which to persuade the students in choosing their concentration of study. The result shows that in term of persuasion effectiveness it is not quite relevant to separate the message and its source. The quality of source is determined by the quality of the message, and vice versa. Separating the two routes of the persuasion process as described in the ELM theory would not be relevant. Abstrak: Persuasi adalah proses komunikasi untuk membentuk atau mengubah sikap, yang dapat dipahami dengan teori Retorika dan teori Elaboration Likelihood Model (ELM. Penelitian ini mengelaborasi teori tersebut dalam Kuliah Umum sebagai sarana mempersuasi mahasiswa untuk memilih konsentrasi studi studi yang didasarkan pada proses pengolahan informasi. Menggunakan metode survey, didapatkan hasil yaitu tidaklah cukup relevan memisahkan pesan dan narasumber dalam melihat efektivitas persuasi. Keduanya menyatu yang berarti bahwa kualitas narasumber ditentukan oleh kualitas pesan yang disampaikannya, dan sebaliknya. Memisahkan proses persuasi dalam dua lajur seperti yang dijelaskan dalam ELM teori menjadi tidak relevan.

  19. THE ELM SURVEY. IV. 24 WHITE DWARF MERGER SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    Kilic, Mukremin [Homer L. Dodge Department of Physics and Astronomy, University of Oklahoma, 440 West Brooks Street, Norman, OK 73019 (United States); Brown, Warren R.; Kenyon, S. J. [Smithsonian Astrophysical Observatory, 60 Garden Street, Cambridge, MA 02138 (United States); Allende Prieto, Carlos [Instituto de Astrofisica de Canarias, E-38205 La Laguna, Tenerife (Spain); Heinke, Craig O. [Department of Physics, CCIS 4-183, University of Alberta, Edmonton, AB, T6G 2E1 (Canada); Agueeros, M. A. [Department of Astronomy, Columbia University, 550 West 120th Street, New York, NY 10027 (United States); Kleinman, S. J., E-mail: kilic@ou.edu [Gemini Observatory, 670 North A' ohoku Place, Hilo, HI 96720 (United States)

    2012-06-01

    We present new radial velocity and X-ray observations of extremely low mass (ELM, {approx}0.2 M{sub Sun }) white dwarf (WD) candidates in the Sloan Digital Sky Survey Data Release 7 area. We identify seven new binary systems with 1-18 hr orbital periods. Five of the systems will merge due to gravitational wave radiation within 10 Gyr, bringing the total number of merger systems found in the ELM Survey to 24. The ELM Survey has now quintupled the known merger WD population. It has also discovered the eight shortest period detached binary WD systems currently known. We discuss the characteristics of the merger and non-merger systems observed in the ELM Survey, including their future evolution. About half of the systems have extreme mass ratios. These are the progenitors of the AM Canum Venaticorum systems and Type Ia supernovae. The remaining targets will lead to the formation of extreme helium stars, subdwarfs, or massive WDs. We identify three targets that are excellent gravitational wave sources. These should be detected by the Laser Interferometer Space Antenna like missions within the first year of operation. The remaining targets are important indicators of what the Galactic foreground may look like for gravitational wave observatories.

  20. Characterization of subsurface stratigraphy along the lower American River floodplain using electrical resistivity, Sacramento, California, 2011

    Science.gov (United States)

    Burton, Bethany L.; Powers, Michael H.; Ball, Lyndsay B.

    2014-01-01

    In July 2011, the U.S. Geological Survey, in cooperation with the U.S. Army Corps of Engineers, completed a geophysical survey using electrical resistivity along an approximately 6-mile reach of the lower American River in Sacramento, California, to map near-surface lithological variations. This survey is a part of a manifold and comprehensive study of river-flow dynamics and geologic boundary-property knowledge necessary to estimate scour potential and levee erosion risk. Data were acquired on the left (south or west) bank between river mile 5 and 10.7 as well as a short section on the right bank from river mile 5.4 to 6. Thirteen direct-current resistivity profiles and approximately 8.3 miles of capacitively coupled resisistivity data were acquired along accessible areas of the floodplain between the levee and river bank. Capacitively coupled resistivity was used as a reconnaissance tool, because it allowed for greater spatial coverage of data but with lower resolution and depth of investigation than the DC resistivity method. The study area contains Pleistocene-age alluvial deposits, dominated by gravels, sands, silts, and clays, that vary in both lateral extent and depth. Several generations of lithologic logs were used to help interpret resistivity variations observed in the resistivity models.

  1. Faith and feminism: how African American women from a storefront church resist oppression in healthcare.

    Science.gov (United States)

    Abrums, Mary

    2004-01-01

    It is well documented that racism in the US healthcare system, including the objectification and disparagement of women of color, contributes to disparities in health status. However, it is a mistaken notion to characterize women of color as unknowing victims. In this study, black feminist standpoint epistemology is used in methodological approach and analysis to understand how a small group of African American church-going women use religious beliefs to help them cope with and resist the racism and discriminatory objectification they encounter in healthcare encounters.

  2. Lateral deflection of the SOL plasma during a giant ELM

    International Nuclear Information System (INIS)

    Landman, I.S.; Wuerz, H.

    2001-01-01

    In recent H-mode experiments at JET with giant ELMs a lateral deflection of hot tokamak plasma striking the divertor plate has been observed. This deflection can effect the divertor erosion caused by the hot plasma irradiation. Based on the MHD model for the vapor shield plasma and the hot plasma, the Seebeck effect is analyzed for explanation of the deflection. At t=-∞ both plasmas are at rest and separated by a boundary parallel to the target. The interaction between plasmas develops gradually ('adiabatically') as exp(t/t 0 ) with t 0 ∼10 2 μs the ELM duration time. At inclined impact of the magnetized hot plasma a toroidal current develops in the interaction zone of the plasmas. The JxB force accelerates the interacting plasmas in the lateral direction. The cold plasma motion essentially compensates the current. The magnitude of the hot plasma deflection is comparable to the observed one

  3. C-reactive protein and cardiac vagal activity following resistance exercise training in young African-American and white men.

    Science.gov (United States)

    Heffernan, Kevin S; Jae, Sae Young; Vieira, Victoria J; Iwamoto, Gary A; Wilund, Kenneth R; Woods, Jeffrey A; Fernhall, Bo

    2009-04-01

    African Americans have a greater prevalence of hypertension and diabetes compared with white Americans, and both autonomic dysregulation and inflammation have been implicated in the etiology of these disease states. The purpose of this study was to examine the cardiac autonomic and systemic inflammatory response to resistance training in young African-American and white men. Linear (time and frequency domain) and nonlinear (sample entropy) heart rate variability, baroreflex sensitivity, tonic and reflex vagal activity, and postexercise heart rate recovery were used to assess cardiac vagal modulation. C-reactive protein (CRP) and white blood cell count were used as inflammatory markers. Twenty two white and 19 African-American men completed 6 wk of resistance training followed by 4 wk of exercise detraining (Post 2). Sample entropy, tonic and reflex vagal activity, and heart rate recovery were increased in white and African-American men following resistance training (P training, with reductions being maintained following detraining (P training improves cardiac autonomic function and reduces inflammation in African-American men, and these adaptations remained after the cessation of training. Resistance training may be an important lifestyle modification for improving cardiac autonomic health and reducing inflammation in young African-American men.

  4. Effects of ELMs and disruptions on ITER divertor armour materials

    Science.gov (United States)

    Federici, G.; Zhitlukhin, A.; Arkhipov, N.; Giniyatulin, R.; Klimov, N.; Landman, I.; Podkovyrov, V.; Safronov, V.; Loarte, A.; Merola, M.

    2005-03-01

    This paper describes the response of plasma facing components manufactured with tungsten (macro-brush) and CFC to energy loads characteristic of Type I ELMs and disruptions in ITER, in experiments conducted (under an EU/RF collaboration) in two plasma guns (QSPA and MK-200UG) at the TRINITI institute. Targets were exposed to a series of repetitive pulses in QSPA with heat loads in a range of 1-2 MJ/m 2 lasting 0.5 ms. Moderate tungsten erosion, of less than 0.2 μm per pulse, was found for loads of ˜1.5 MJ/m 2, consistent with ELM erosion being determined by tungsten evaporation and not by melt layer displacement. At energy densities of ˜1.8 MJ/m 2 a sharp growth of tungsten erosion was measured together with intense droplet ejection. MK-200UG experiments were focused on studying mainly vapor plasma production and impurity transport during ELMs. The conditions for removal of thin metal deposits from a carbon substrate were characterized.

  5. Effects of ELMs and disruptions on ITER divertor armour materials

    International Nuclear Information System (INIS)

    Federici, G.; Zhitlukhin, A.; Arkhipov, N.; Giniyatulin, R.; Klimov, N.; Landman, I.; Podkovyrov, V.; Safronov, V.; Loarte, A.; Merola, M.

    2005-01-01

    This paper describes the response of plasma facing components manufactured with tungsten (macro-brush) and CFC to energy loads characteristic of Type I ELMs and disruptions in ITER, in experiments conducted (under an EU/RF collaboration) in two plasma guns (QSPA and MK-200UG) at the TRINITI institute. Targets were exposed to a series of repetitive pulses in QSPA with heat loads in a range of 1-2 MJ/m 2 lasting 0.5 ms. Moderate tungsten erosion, of less than 0.2 μm per pulse, was found for loads of ∼1.5 MJ/m 2 , consistent with ELM erosion being determined by tungsten evaporation and not by melt layer displacement. At energy densities of ∼1.8 MJ/m 2 a sharp growth of tungsten erosion was measured together with intense droplet ejection. MK-200UG experiments were focused on studying mainly vapor plasma production and impurity transport during ELMs. The conditions for removal of thin metal deposits from a carbon substrate were characterized

  6. Recent Trends in ELM and MLELM: A review

    Directory of Open Access Journals (Sweden)

    R. Manju Parkavi

    2017-01-01

    Full Text Available Extreme Learning Machine (ELM is a high effective learning algorithm for the single hidden layer feed forward neural networks. Compared with the existing neural network learning algorithm it solves the slow training speed and over-fitting problems. It has been used in different fields and applications such as biomedical engineering, computer vision, remote sensing, chemical process and control and robotics. It has better generalization stability, sparsity, accuracy, robustness, optimal control and fast learning rate This paper introduces a brief review about ELM and MLELM, describing the principles and latest research progress about the algorithms, theories and applications. Next, Multilayer Extreme Learning Machine (MLELM and other state-of-the-art classifiers are trained on this suitable training feature vector for classification of data. Deep learning has the advantage of approximating the complicated function and mitigating the optimization difficulty associated with deep models. Multilayer extreme learning machine is a learning algorithm of an Artificial Neural Network (ANN which takes to be good for deep learning and extreme learning machine. This review presents a comprehensive view of these advances in ELM and MLELM which may be worthy of exploring in the future.

  7. ELM-free and inter-ELM divertor heat flux broadening induced by edge harmonics oscillation in NSTX

    Science.gov (United States)

    Gan, K. F.; Ahn, J.-W.; Gray, T. K.; Zweben, S. J.; Fredrickson, E. D.; Scotti, F.; Maingi, R.; Park, J.-K.; Canal, G. P.; Soukhanovskii, V. A.; Mclean, A. G.; Wirth, B. D.

    2017-12-01

    A new n  =  1 dominated edge harmonic oscillation (EHO) has been found in NSTX. The new EHO, rotating toroidally in the counter-current direction and the opposite direction of the neutral beam, was observed during certain inter-ELM and ELM-free periods of H-mode operation. This EHO is associated with a significant broadening of the integral heat flux width ({λ\\operatorname{int}} ) by up to 150%, and a decrease in the divertor peak heat flux by  >60%. An EHO induced filament was also observed by the gas puff imaging diagnostic. The toroidal rotating filaments could change the edge magnetic topology resulting in toroidal rotating strike point splitting and heat flux broadening. Experimental result of the counter current rotation of strike points splitting is consistent with the counter-current EHO.

  8. Simulation of tungsten armour cracking due to small ELMs in ITER

    Energy Technology Data Exchange (ETDEWEB)

    Pestchanyi, S., E-mail: sergey.pestchanyi@ihm.fzk.de [Forschungszentrum Karlsruhe, IHM (Germany); Garkusha, I. [Institute of Plasma Physics of the NSC KIPT, Kharkov 61108 (Ukraine); Landman, I. [Forschungszentrum Karlsruhe, IHM (Germany)

    2010-12-15

    Simulations of tungsten armour cracking under small ELM-like plasma heat load, which does not cause surface melting, have been performed using the PEGASUS-3D code. A dedicated series of experiments have been performed in the QSPA-Kh50 facility for measurements of the unknown tungsten thermophysical properties and for verification of the PEGASUS-3D simulation results. The simulations revealed that a cellular crack network with average mesh size {Lambda} {approx} 0.5 mm formed after first ELMs and the pattern does not change further. With increasing number of repetitive ELMs loads, the average crack width {Delta}(n) has a maximum value {Delta}{sub m}. The ratio of {Delta}{sub m}/{Lambda} is equal to the tungsten thermal expansion at the maximum surface temperature. {Delta}(n) tends to this value exponentially. The number of ELMs n{sub m} needed for {Delta} stabilization depends on the ELMs energy density and time duration, n{sub m} {approx} 300 for the simulated ELMs of 0.45 MJ/m{sup 2} and 0.25 ms duration. The PEGASUS-3D code is prepared for simulations of tungsten armour damage under action of ELMs of various energy deposition and time duration. These parameters of ELMs depend on ITER regimes of operation and on how successful will be the efforts on ELMs mitigation.

  9. Simulation of tungsten armour cracking due to small ELMs in ITER

    International Nuclear Information System (INIS)

    Pestchanyi, S.; Garkusha, I.; Landman, I.

    2010-01-01

    Simulations of tungsten armour cracking under small ELM-like plasma heat load, which does not cause surface melting, have been performed using the PEGASUS-3D code. A dedicated series of experiments have been performed in the QSPA-Kh50 facility for measurements of the unknown tungsten thermophysical properties and for verification of the PEGASUS-3D simulation results. The simulations revealed that a cellular crack network with average mesh size Λ ∼ 0.5 mm formed after first ELMs and the pattern does not change further. With increasing number of repetitive ELMs loads, the average crack width Δ(n) has a maximum value Δ m . The ratio of Δ m /Λ is equal to the tungsten thermal expansion at the maximum surface temperature. Δ(n) tends to this value exponentially. The number of ELMs n m needed for Δ stabilization depends on the ELMs energy density and time duration, n m ∼ 300 for the simulated ELMs of 0.45 MJ/m 2 and 0.25 ms duration. The PEGASUS-3D code is prepared for simulations of tungsten armour damage under action of ELMs of various energy deposition and time duration. These parameters of ELMs depend on ITER regimes of operation and on how successful will be the efforts on ELMs mitigation.

  10. Seismic design of steel moment resisting frames-European versus American practice

    International Nuclear Information System (INIS)

    Naqash, M.T.; Matteis, G.D.; Luca, A.D.

    2012-01-01

    This paper provides an overview on the design philosophy of moment resisting frames (MRF) according to the seismic provisions of Eurocode 8 and American Institute of Steel Construction (AISC). A synopsis of the main recommendations of the two codes is briefly described. Then in order to examine the structural efficiency of the design principles of MRF according to the aforementioned codes, a case study is developed in which spatial and perimeter moment resisting frames of 12, 6 and 3 storeys residential building are considered. In the case of EC8, Ductility Class Medium (DCM) with behaviour factor of 4 and Ductility Class High (DCH) with behaviour factor of 6.5 for 6-storey frames are used, while only DCH is employed in the design of 12 and 3 storey frames. When dealing with AISC/American Society of Civil Engineers (ASCE) code, special moment resisting frame (SMF) with response modification factor of 8 is employed in the design. The outcomes from the design are illustrated in terms of frame performance, section profiles, strength-demand to capacity ratios, drift-demand to capacity ratios and structural weight, thus allowing the understanding of pros and cons of the design criteria and the capacity design rules of the two codes. The main purpose of the current paper is to compare the seismic design rules of the two codes with a parametric analysis developed by a case study in order to let the technician knows about the importance and influence of some important parameters which are given in the capacity design rules of the two codes. This study will be a benchmark for further analysis on the two codes for seismic design of steel structures. (author)

  11. Range Expansion and the Origin of USA300 North American Epidemic Methicillin-Resistant Staphylococcus aureus

    Directory of Open Access Journals (Sweden)

    Lavanya Challagundla

    2018-01-01

    Full Text Available The USA300 North American epidemic (USA300-NAE clone of methicillin-resistant Staphylococcus aureus has caused a wave of severe skin and soft tissue infections in the United States since it emerged in the early 2000s, but its geographic origin is obscure. Here we use the population genomic signatures expected from the serial founder effects of a geographic range expansion to infer the origin of USA300-NAE and identify polymorphisms associated with its spread. Genome sequences from 357 isolates from 22 U.S. states and territories and seven other countries are compared. We observe two significant signatures of range expansion, including decreases in genetic diversity and increases in derived allele frequency with geographic distance from the Pennsylvania region. These signatures account for approximately half of the core nucleotide variation of this clone, occur genome wide, and are robust to heterogeneity in temporal sampling of isolates, human population density, and recombination detection methods. The potential for positive selection of a gyrA fluoroquinolone resistance allele and several intergenic regions, along with a 2.4 times higher recombination rate in a resistant subclade, is noted. These results are the first to show a pattern of genetic variation that is consistent with a range expansion of an epidemic bacterial clone, and they highlight a rarely considered but potentially common mechanism by which genetic drift may profoundly influence bacterial genetic variation.

  12. Genealogical Analysis of the North-American Spring Wheat Varieties with Different Resistance to Pre-harvest Sprouting

    Directory of Open Access Journals (Sweden)

    Martynov Sergey

    2016-12-01

    Full Text Available A comparative analysis of genetic diversity of North American spring wheat varieties differing in resistance to pre-harvest sprouting was carried out. For identification of sources of resistance the genealogical profiles of 148 red-grained and 63 white-grained North-American spring wheat varieties with full pedigrees were calculated and estimates were made of pre-harvest sprouting. The cluster structure of the populations of red-grained and white-grained varieties was estimated. Analysis of variance revealed significant differences between the average contributions of landraces in the groups of resistant and susceptible varieties. Distribution of the putative sources of resistance in the clusters indicated that varieties having different genetic basis may have different sources of resistance. For red-grained varieties the genetic sources of resistance to pre-harvest sprouting are landraces Crimean, Hard Red Calcutta, and Iumillo, or Button, Kenya 9M-1A-3, and Kenya-U, or Red Egyptian and Kenya BF4-3B-10V1. Tracking of pedigrees showed these landraces contributed to the pedigrees, respectively, via Thatcher, Kenya-Farmer, and Kenya-58, which were likely donors of resistance for red-grained varieties. For white-grained varieties the sources of resistance were landraces Crimean, Hard Red Calcutta, Ostka Galicyjska, Iumillo, Akakomugi, Turco, Hybrid English, Rough Chaff White and Red King, and putative donors of resistance — Thatcher, RL2265, and Frontana. The genealogical profile of accession RL4137, the most important donor of resistance to pre-harvest sprouting in North American spring wheat breeding programmes, contains almost all identified sources of resistance.

  13. Co-occurence of Two Invasive Species: The Banded and European Elm Bark Beetles (Coleoptera: Scolytidae)

    Science.gov (United States)

    The invasive European elm bark beetle, Scolytus multistriatus (Marsham), was first detected a century ago and now occurs in most of the continental United States. The invasive banded elm bark beetle, Scolytus schevyrewi Semenov, native to Asia, was discovered in the United States in 2003 and is now...

  14. Phospho.ELM: a database of phosphorylation sites--update 2011

    DEFF Research Database (Denmark)

    Dinkel, Holger; Chica, Claudia; Via, Allegra

    2011-01-01

    The Phospho.ELM resource (http://phospho.elm.eu.org) is a relational database designed to store in vivo and in vitro phosphorylation data extracted from the scientific literature and phosphoproteomic analyses. The resource has been actively developed for more than 7 years and currently comprises ...

  15. Biology of the invasive banded elm bark beetle (Coleoptera: Scolytidae) in the western United States

    Science.gov (United States)

    Jana C. Lee; Jose F. Negron; Sally J. McElwey; Livy Williams; Jeffrey J. Witcosky; John B. Popp; Steven J. Seybold

    2011-01-01

    The banded elm bark beetle, Scolytus schevyrewi Semenov (Coleoptera: Scolytidae), native to Asia, was detected in the United States in 2003, and as of 2011 it is known to occur in 28 states and four Canadian provinces. S. schevyrewi infests the same elm (Ulmus spp.) hosts as the longestablished invasive...

  16. ELM-ART--An Interactive and Intelligent Web-Based Electronic Textbook

    Science.gov (United States)

    Weber, Gerhard; Brusilovsky, Peter

    2016-01-01

    This paper present provides a broader view on ELM-ART, one of the first Web-based Intelligent Educational systems that offered a creative combination of two different paradigms--Intelligent Tutoring and Adaptive Hypermedia technologies. The unique dual nature of ELM-ART contributed to its long life and research impact and was a result of…

  17. Effect of ELMs on rotation and momentum confinement in H-mode discharges in JET

    DEFF Research Database (Denmark)

    Versloot, T.W.; de Vries, P.C.; Giroud, C.

    2010-01-01

    The loss of plasma toroidal angular momentum and thermal energy by edge localized modes (ELMs) has been studied in JET. The analysis shows a consistently larger drop in momentum in comparison with the energy loss associated with the ELMs. This difference originates from the large reduction in ang...

  18. Enhancement of ELM by Clustering Discrimination Manifold Regularization and Multiobjective FOA for Semisupervised Classification

    OpenAIRE

    Qing Ye; Hao Pan; Changhua Liu

    2015-01-01

    A novel semisupervised extreme learning machine (ELM) with clustering discrimination manifold regularization (CDMR) framework named CDMR-ELM is proposed for semisupervised classification. By using unsupervised fuzzy clustering method, CDMR framework integrates clustering discrimination of both labeled and unlabeled data with twinning constraints regularization. Aiming at further improving the classification accuracy and efficiency, a new multiobjective fruit fly optimization algorithm (MOFOA)...

  19. THE ELM SURVEY. III. A SUCCESSFUL TARGETED SURVEY FOR EXTREMELY LOW MASS WHITE DWARFS

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Warren R.; Kenyon, Scott J. [Smithsonian Astrophysical Observatory, 60 Garden St., Cambridge, MA 02138 (United States); Kilic, Mukremin [Homer L. Dodge Department of Physics and Astronomy, University of Oklahoma, 440 W. Brooks St., Norman, OK 73019 (United States); Allende Prieto, Carlos, E-mail: wbrown@cfa.harvard.edu, E-mail: skenyon@cfa.harvard.edu, E-mail: kilic@ou.edu, E-mail: callende@iac.es [Instituto de Astrofisica de Canarias, E-38205, La Laguna, Tenerife (Spain)

    2012-01-10

    Extremely low mass (ELM) white dwarfs (WDs) with masses < 0.25 M{sub Sun} are rare objects that result from compact binary evolution. Here, we present a targeted spectroscopic survey of ELM WD candidates selected by color. The survey is 71% complete and has uncovered 18 new ELM WDs. Of the seven ELM WDs with follow-up observations, six are short-period binaries and four have merger times less than 5 Gyr. The most intriguing object, J1741+6526, likely has either a pulsar companion or a massive WD companion making the system a possible supernova Type Ia or an Ia progenitor. The overall ELM survey has now identified 19 double degenerate binaries with <10 Gyr merger times. The significant absence of short orbital period ELM WDs at cool temperatures suggests that common envelope evolution creates ELM WDs directly in short period systems. At least one-third of the merging systems are halo objects, thus ELM WD binaries continue to form and merge in both the disk and the halo.

  20. Structure, stability and ELM dynamics of the H-mode pedestal in DIII-D

    International Nuclear Information System (INIS)

    Fenstermacher, M.E.; Leonard, A.W.; Osborne, T.H.

    2005-01-01

    Experiments are described that have increased understanding of the transport and stability physics that set the H-mode edge pedestal width and height, determine the onset of Type-I edge localized modes (ELMs), and produce the nonlinear dynamics of the ELM perturbation in the pedestal and scrape-off layer (SOL). Predictive models now exist for the n e pedestal profile and the p e height at the onset of Type-I ELMs, and progress has been made toward predictive models of the T e pedestal width and nonlinear ELM evolution. Similarity experiments between DIII-D and JET suggested that neutral penetration physics dominates in the relationship between the width and height of the n e pedestal while plasma physics dominates in setting the T e pedestal width. Measured pedestal conditions including edge current at ELM onset agree with intermediate-n peeling-ballooning (P-B) stability predictions. Midplane ELM dynamics data show the predicted (P-B) structure at ELM onset, large rapid variations of the SOL parameters, and fast radial propagation in later phases, similar to features in nonlinear ELM simulations. (author)

  1. Global Transmission and Local Consumption: Navajo Resistance to Mainstream American Television

    Directory of Open Access Journals (Sweden)

    Sam Pack

    2011-04-01

    Full Text Available A common assumption maintains that the global outreach of mass media inevitably leads to deleterious consequences for native communities. Indeed, different scholars have argued that awareness of the outside world from television results in the homogenization of local cultures. However, images viewed through the electronic peephole radically transform not only an understanding of the outside world, but the way indigenes define themselves and their relationship to each other. By presenting subaltern audiences with an idealized other, television compels the emergence of an objectified self. “Who are ‘we’?” would not have been asked—or asked in the same way—were it not for the “Who are ‘they’?” necessitated by the introduction of television. In this article, I examine a particular group of subaltern viewers who reassign the roles of “self” and “other” in order to preserve, defend, and construct their own selfhood. Because they look and act differently from those in the mediated mainstream, Navajo television viewers create oppositional identities by understanding themselves first in relation to and then against standardized models. Resisting mainstream American television is a way of articulating experiences of powerlessness in a white-dominated society as well as a means of communicating a discourse of resistance to the dominant ideology.

  2. Comparisons of protein profiles of beech bark disease resistant and susceptible American beech (Fagus grandifolia

    Directory of Open Access Journals (Sweden)

    Mason Mary E

    2013-01-01

    Full Text Available Abstract Background Beech bark disease is an insect-fungus complex that damages and often kills American beech trees and has major ecological and economic impacts on forests of the northeastern United States and southeastern Canadian forests. The disease begins when exotic beech scale insects feed on the bark of trees, and is followed by infection of damaged bark tissues by one of the Neonectria species of fungi. Proteomic analysis was conducted of beech bark proteins from diseased trees and healthy trees in areas heavily infested with beech bark disease. All of the diseased trees had signs of Neonectria infection such as cankers or fruiting bodies. In previous tests reported elsewhere, all of the diseased trees were demonstrated to be susceptible to the scale insect and all of the healthy trees were demonstrated to be resistant to the scale insect. Sixteen trees were sampled from eight geographically isolated stands, the sample consisting of 10 healthy (scale-resistant and 6 diseased/infested (scale-susceptible trees. Results Proteins were extracted from each tree and analysed in triplicate by isoelectric focusing followed by denaturing gel electrophoresis. Gels were stained and protein spots identified and intensity quantified, then a statistical model was fit to identify significant differences between trees. A subset of BBD differential proteins were analysed by mass spectrometry and matched to known protein sequences for identification. Identified proteins had homology to stress, insect, and pathogen related proteins in other plant systems. Protein spots significantly different in diseased and healthy trees having no stand or disease-by-stand interaction effects were identified. Conclusions Further study of these proteins should help to understand processes critical to resistance to beech bark disease and to develop biomarkers for use in tree breeding programs and for the selection of resistant trees prior to or in early stages of BBD

  3. Multiclass AdaBoost ELM and Its Application in LBP Based Face Recognition

    Directory of Open Access Journals (Sweden)

    Yunliang Jiang

    2015-01-01

    Full Text Available Extreme learning machine (ELM is a competitive machine learning technique, which is simple in theory and fast in implementation; it can identify faults quickly and precisely as compared with traditional identification techniques such as support vector machines (SVM. As verified by the simulation results, ELM tends to have better scalability and can achieve much better generalization performance and much faster learning speed compared with traditional SVM. In this paper, we introduce a multiclass AdaBoost based ELM ensemble method. In our approach, the ELM algorithm is selected as the basic ensemble predictor due to its rapid speed and good performance. Compared with the existing boosting ELM algorithm, our algorithm can be directly used in multiclass classification problem. We also carried out comparable experiments with face recognition datasets. The experimental results show that the proposed algorithm can not only make the predicting result more stable, but also achieve better generalization performance.

  4. THE ELM SURVEY. II. TWELVE BINARY WHITE DWARF MERGER SYSTEMS

    International Nuclear Information System (INIS)

    Kilic, Mukremin; Brown, Warren R.; Kenyon, S. J.; Prieto, Carlos Allende; Agueeros, M. A.; Heinke, Craig

    2011-01-01

    We describe new radial velocity and X-ray observations of extremely low-mass white dwarfs (ELM WDs, ∼0.2 M sun ) in the Sloan Digital Sky Survey Data Release 4 and the MMT Hypervelocity Star survey. We identify four new short period binaries, including two merger systems. These observations bring the total number of short period binary systems identified in our survey to 20. No main-sequence or neutron star companions are visible in the available optical photometry, radio, and X-ray data. Thus, the companions are most likely WDs. Twelve of these systems will merge within a Hubble time due to gravitational wave radiation. We have now tripled the number of known merging WD systems. We discuss the characteristics of this merger sample and potential links to underluminous supernovae, extreme helium stars, AM CVn systems, and other merger products. We provide new observational tests of the WD mass-period distribution and cooling models for ELM WDs. We also find evidence for a new formation channel for single low-mass WDs through binary mergers of two lower mass objects.

  5. Update on exotic ash collection for hybrid breeding and survey for EAB-resistance in native North American species

    Science.gov (United States)

    Mary E. Mason; Daniel A. Herms; David W. Carey; Kathleen S. Knight; Nurul I. Faridi; Jennifer. Koch

    2011-01-01

    Contrary to the high levels of devastation observed on North American ash species infested with emerald ash borer (EAB) (Agrilus planipennis Fairmaire), reports from Asia indicate that EAB-induced destruction of Asian ash species is limited to stressed trees. This indicates that Asian ash species have co-evolved resistance, or at least a high degree...

  6. The MHD stability analysis of type I ELMS in ASDEX Upgrade Tokamak

    International Nuclear Information System (INIS)

    Saarelma, S.

    2000-01-01

    The ELMs or edge localized modes are plasma instabilities localized in the edge region of a tokamak plasma. They cause periodic expulsions of particles and energy. The ELMs play a significant role in the confinement of the plasma, helium exhaust and diverter erosion. These are crucial issues in tokamak operation and, thus, understanding the underlying physical mechanism behind the ELM phenomenon is very important. The ELMs are classified into three different types based on the plasma conditions, where they are observed, and, on the ELM frequency response to the heating power. In this thesis, type I ELMs which are the most intense and the most damaging to the diverters, are studied. A model for the ELMs presented by Connor et al. is tested in experimental ASDEX Upgrade plasmas. In the Connor model, the ELMs are explained as a result of two instabilities, ballooning and peeling modes. Also a phenomenon called the bootstrap current plays a significant role by being the destabilising trigger to the peeling modes. The method used to study the model is MHD or magnetohydrodynamics. The theory of the ideal MHD equilibrium and the linear stability analysis is described. Inclusion of the bootstrap current to the equilibrium construction is introduced. The equilibria are created using experimental data from plasma shots that display type I ELMs. The stability analysis indicates that the investigated ELM model is a feasible explanation for type I ELMs. The pressure gradient near the plasma edge was found to be close to the ballooning stability boundary as predicted by the model. The peeling mode stability analysis confirms the prediction of the model that as the bootstrap current increases, the plasma becomes unstable for peeling modes with low to intermediate toroidal mode numbers. The mode numbers agree with the experimental results. In the experiments with high triangularity, low ELM frequency and ELM-free periods were observed. This indicates better stability of the plasma

  7. Non-Ideal ELM Stability and Non-Axisymmetric Field Penetration Calculations with M3D-C1

    Science.gov (United States)

    Ferraro, N. M.; Chu, M. S.; Snyder, P. B.; Jardin, S. C.; Luo, X.

    2009-11-01

    Numerical studies of ELM stability and non-axisymmetric field penetration in diverted DIII-D and NSTX equilibria are presented, with resistive and finite Larmor radius effects included. These results are obtained with the nonlinear two-fluid code M3D-C1, which has recently been extended to allow linear non-axisymmetric calculations. Benchmarks of M3D-C1 with ideal codes ELITE and GATO show good agreement for the linear stability of peeling-ballooning modes in the ideal limit. New calculations of the resistive stability of ideally stable DIII-D equilibria are presented. M3D-C1 has also been used to calculate the linear response to non-axisymmetric external fields; these calculations are benchmarked with Surfmn and MARS-F. New numerical methods implemented in M3D-C1 are presented, including the treatment of boundary conditions with C^1 elements in a non-rectangular mesh.

  8. ELM Suppression and performance improvement with a flowing liquid lithium limiter in EAST

    Science.gov (United States)

    Zuo, G. Z.; Hu, J. S.; Maingi, R.; Sun, Z.; Xu, W.; Li, J. G.; Diallo, A.; Lunsford, R.; Osborne, T.; Tritz, K.; EAST Team

    2017-10-01

    Improvements in plasma performance were observed using a second-generation flowing liquid lithium limiter (FLiLi) in EAST. Compared to the H mode discharges without FLiLi, ELM frequency and amplitude were both lower with FLiLi. Also, ELM frequency and amplitude gradually decreased discharge-by-discharge with FLiLi, similar to the gradual ELM mitigation by real-time Li aerosol injection in successive discharges. Moreover, transient ELM-free H-modes with a strong increase of WMHD and H98 were observed for the first time with FLiLi. During the ELM-free phases, MHD activity interpreted from high frequency Mirnov probes differed from activity in the ELMy phases. In addition to the typical low-frequency 50 kHz edge coherent MHD mode (ECM), a second mode 220-240 kHz also was observed in the ELM-free phase. By computing the Li efflux from the FLiLi limiter surface, it was found that the Li efflux from sputtering during discharges and evaporation between discharges was comparable to the typical mass delivery rates used for Li powder injection rate during plasma operation in EAST. Therefore, gradual accumulation of Li in EAST via real time Li efflux from the FLiLi surface produces similar effects to aerosol injection, i.e. reduced recycling, enhanced fluctuations, and ELM mitigation.

  9. The Prediction of Yarn Elongation of Kenyan Ring-Spun Yarn using Extreme Learning Machines (ELM

    Directory of Open Access Journals (Sweden)

    Josphat Igadwa Mwasiagi

    2017-03-01

    Full Text Available The optimization of the manufacture of cotton yarns involves several processes, while the prediction of yarn quality parameters forms an important area of investigation. This research work concentrated on the prediction of cotton yarn elongation. Cotton lint and yarn samples were collected in textile factories in Kenya.The collected samples were tested under standard testing conditions. Cotton lint parameters, machine parameters and yarn elongation were used to design yarn elongation prediction models. The elongation prediction models used three network training algorithms, including backpropagation (BP, an extreme learning machine (ELM, and a hybrid of differential evolution (DE and an ELM referred to as DE-ELM. The prediction models recorded a mean squared error (mse value of 0.001 using 11, 43 and 2 neurons in the hidden layer for the BP, ELM and DE-ELM models respectively. The ELM models exhibited faster training speeds than the BP algorithms, but required more neurons in the hidden layer than other models. The DEELM hybrid algorithm was faster than the BP algorithm, but slower than the ELM algorithm.

  10. Discriminant analysis to predict the occurrence of ELMs in H-mode discharges

    International Nuclear Information System (INIS)

    Kardaun, O.J.W.F.; Itoh, S.; Itoh, K.; Kardaun, J.W.P.F.

    1993-08-01

    After an exposition of its theoretical background, discriminant analysis is applied to the H-mode confinement database to find the region in plasma parameter space in which H-mode with small ELMs (Edge Localized Modes) is likely to occur. The boundary of this region is determined by the condition that the probability of appearance of such a type of H-mode, as a function of the plasma parameters, should be (1) larger than some threshold value and (2) larger than the corresponding probability for other types of H-mode (i.e., H-mode without ELMs or with giant ELMs). In practice, the discrimination has been performed for the ASDEX, JET and JFT-2M tokamaks (a) using four instantaneous plasma parameters (injected power P inj , magnetic field B t , plasma current I p and line averaged electron density (n-bar e ) and (b) taking also memory effects of the plasma and the distance between the plasma and the wall into account, while using variables that are normalised with respect to machine size. Generally speaking, it is found that there is a substantial overlap between the region of H-mode with small ELMs and the region of the two other types of H-mode. However, the ELM-free and the giant ELM H-modes relatively rarely appear in the region, that, according to the analysis, is allocated to small ELMs. A reliable production of H-mode with only small ELMs seems well possible by choosing this regime in parameter space. In the present study, it was not attempted to arrive at a unified discrimination across the machines. So, projection from one machine to another remains difficult, and a reliable determination of the region where small ELMs occur still requires a training sample from the device under consideration. (author) 53 refs

  11. Real-time control of ELM and sawtooth frequencies: similarities and differences

    Science.gov (United States)

    Lennholm, M.; Frigione, D.; Graves, J. P.; Beaumont, P. S.; Blackman, T.; Carvalho, I. S.; Chapman, I.; Dumont, R.; Felton, R.; Garzotti, L.; Goniche, M.; Goodyear, A.; Grist, D.; Jachmich, S.; Johnson, T.; Lang, P.; Lerche, E.; de la Luna, E.; Monakhov, I.; Mooney, R.; Morris, J.; Nave, M. F. F.; Reich, M.; Rimini, F.; Sips, G.; Sheikh, H.; Sozzi, C.; Tsalas, M.; Contributors, JET

    2016-01-01

    ELMs and Sawteeth, located in different parts of the plasma, are similar from a control engineering point of view. Both manifest themselves through quiescent periods interrupted by periodic collapses. For both, large collapses, following long quiescent periods, have detrimental effects while short periods are associated with decreased confinement. Following the installation of the all metal ‘ITER like wall’ on JET, sawteeth and ELMs also play an important role by expelling tungsten from the core and edge of the plasma respectively. Control of tungsten has therefore been added to divertor heat load reduction, NTM avoidance and helium ash removal as reasons for requiring ELM and sawtooth control. It is therefore of interest to implement control systems to maintain the sawtooth and ELM frequencies in the desired ranges. On JET, ELM frequency control uses radial field ‘kicks’ and pellet and gas injection as actuators, while sawtooth control uses ion cyclotron resonance heating (ICRH). JET experiments have, for the first time, established feedback control of the ELM frequency, via real time variation of the injected gas flow [1]. Using this controller in conjunction with pellet injection allows the ELM frequency to be kept as required despite variations in pellet ELM triggering efficiency. JET Sawtooth control experiments have, for the first time, demonstrated that low field side ICRH, as foreseen for ITER, can shorten sawteeth lengthened by central fast ions [2]. The development of ELM and sawtooth control could be key to achieve stable high performance JET discharges with minimal tungsten content. Integrating such schemes into an overall control strategy will be required in future tokamaks and gaining experience on current tokamaks is essential.

  12. Were the chaotic ELMs in TCV the result of an ARMA process?

    International Nuclear Information System (INIS)

    Degeling, A W; Lister, J B; Martin, Y R; Zvejnieks, G

    2004-01-01

    The results of a previous paper claiming the demonstration that edge localized mode (ELM) dynamics on TCV are chaotic in a number of cases has recently been called into question, because the statistical test employed was found to also identify linear auto regressive-moving average (ARMA) models as chaotic. The TCV ELM data has therefore been re-examined with an improved method that is able to make this distinction, and the ARMA model is found to be an inappropriate description of the dynamics on TCV. The hypothesis that ELM dynamics are chaotic on TCV in a number of cases is therefore still favoured. (letter to the editor)

  13. An interpretation of the structure of ELMs and the H to L transition on JET

    International Nuclear Information System (INIS)

    Cripwell, P.; Edwards, A.; Galvao, R.

    1989-01-01

    Initial studies on JET have described the characteristics of edge fluctuations in X-point plasmas and their effects on energy and particle confinement. In this paper we perform a detailed magnetic analysis of ELMs and their precursors, and make a comparison with the H to L transition. These magnetic results correlate with those of other diagnostics such as the microwave reflectometer and X-point langmuir probes. Localization of ELMs and H to L transition spike is determined with the soft X-ray camera, and particle transport estimated by an H-alpha detector. Finally possible theoretical explanations for ELMs are discussed. (author) 5 refs., 3 figs

  14. THE ELM SURVEY. V. MERGING MASSIVE WHITE DWARF BINARIES

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Warren R.; Kenyon, Scott J. [Smithsonian Astrophysical Observatory, 60 Garden St, Cambridge, MA 02138 (United States); Kilic, Mukremin; Gianninas, A. [Homer L. Dodge Department of Physics and Astronomy, University of Oklahoma, 440 W. Brooks St., Norman, OK, 73019 (United States); Allende Prieto, Carlos, E-mail: wbrown@cfa.harvard.edu, E-mail: skenyon@cfa.harvard.edu, E-mail: kilic@ou.edu, E-mail: alexg@nhn.ou.edu, E-mail: callende@iac.es [Instituto de Astrofisica de Canarias, E-38205, La Laguna, Tenerife (Spain)

    2013-05-20

    We present the discovery of 17 low-mass white dwarfs (WDs) in short-period (P {<=} 1 day) binaries. Our sample includes four objects with remarkable log g {approx_equal} 5 surface gravities and orbital solutions that require them to be double degenerate binaries. All of the lowest surface gravity WDs have metal lines in their spectra implying long gravitational settling times or ongoing accretion. Notably, six of the WDs in our sample have binary merger times <10 Gyr. Four have {approx}>0.9 M{sub Sun} companions. If the companions are massive WDs, these four binaries will evolve into stable mass transfer AM CVn systems and possibly explode as underluminous supernovae. If the companions are neutron stars, then these may be millisecond pulsar binaries. These discoveries increase the number of detached, double degenerate binaries in the ELM Survey to 54; 31 of these binaries will merge within a Hubble time.

  15. THE ELM SURVEY. V. MERGING MASSIVE WHITE DWARF BINARIES

    International Nuclear Information System (INIS)

    Brown, Warren R.; Kenyon, Scott J.; Kilic, Mukremin; Gianninas, A.; Allende Prieto, Carlos

    2013-01-01

    We present the discovery of 17 low-mass white dwarfs (WDs) in short-period (P ≤ 1 day) binaries. Our sample includes four objects with remarkable log g ≅ 5 surface gravities and orbital solutions that require them to be double degenerate binaries. All of the lowest surface gravity WDs have metal lines in their spectra implying long gravitational settling times or ongoing accretion. Notably, six of the WDs in our sample have binary merger times 0.9 M ☉ companions. If the companions are massive WDs, these four binaries will evolve into stable mass transfer AM CVn systems and possibly explode as underluminous supernovae. If the companions are neutron stars, then these may be millisecond pulsar binaries. These discoveries increase the number of detached, double degenerate binaries in the ELM Survey to 54; 31 of these binaries will merge within a Hubble time.

  16. Bird mortality following DDT spray for Dutch elm disease

    Science.gov (United States)

    Wurster, D.H.; Wurster, C.F.; Strickland, W.N.

    1965-01-01

    Avian populations in Hanover, N. H., a town that has sprayed its elms with DDT for many years in an attempt to control Dutch elm disease, were compared with those in Norwich, Vt., a town 1 mile (1.6 km) west of Hanover that has never sprayed. Hanover applied 109 lb DDT/acre (2.1 kg/hectare) in April 1963, then used Methoxychlor in April 1964. Population surveys were taken regularly during spring and early summer of these years, dead birds were collected in both towns, and 106 birds were analyzed for DDT, DDE, and DDD. Severe mortality of both resident and migrant birds occurred in Hanover during spring 1963, and the evidence implicates DDT as its cause. Robin loss was estimated at 70% of the resident population, or 350 to 400 individuals, but mortality among other species of widely varied feeding habits was also substantial. Feeding habits suggest that some birds acquired the toxicant by eating living insects carrying DDT, presenting the paradox of survival of the intended DDT victims, and death, instead, of insectivorous birds. Organ and whole bird analyses are presented and criteria for establishing cause of death are discussed. Most of the DDT had been converted to DDE and DDD, and residues were found in all organs analyzed. Robin mortality was reduced, but not eliminated following Methoxychlor application in 1964; these losses were believed caused by residual DDT in the soil. There was no evidence DDT poisoning among other species in 1964, though the dead birds collected were not analyzed.

  17. Making history: Field testing of blight-resistant American chestnut (Castanea dentata) in the Southern Region

    Science.gov (United States)

    Stacy L. Clark; Scott E. Schlarbaum; A.M. Saxton; Fred V. Hebard

    2011-01-01

    The American chestnut (Castanea dentata Marsh. Borkh.) was decimated by an exotic fungus (chestnut blight [Cryphonectria parasitica Murr. Bar]) in the early part of the 20th century. The American Chestnut Foundation (TACF) uses a back-cross breeding program to produce a tree that is predicted to be American chestnut in character...

  18. Geographic Variation in Phosphine Resistance Among North American Populations of the Red Flour Beetle (Coleoptera: Tenebrionidae).

    Science.gov (United States)

    Cato, A J; Elliott, Brent; Nayak, Manoj K; Phillips, Thomas W

    2017-06-01

    The red flour beetle, Tribolium castaneum (Herbst), is a common stored-product pest found worldwide. Phosphine, hydrogen phosphide (PH3), is the most commonly used fumigant for stored grains, for which genetically based resistance has been recorded for several pest species. This study assessed phosphine resistance in 25 T. castaneum populations from across the United States and Canada using a discriminating dose bioassay. Dose-mortality assays were conducted with adults from seven of these populations to categorize weak and strong resistance phenotypes. Phosphine resistance was detected in 12 out of the 25 populations, and the frequency of resistance within populations varied from 2% in Victoria, TX, to 100% in Red Level, AL. Two resistant populations from Kansas that had been sampled three years earlier were found to have similar resistance frequencies in the current study. None of the four Canadian populations had any detectable resistance among the insects tested. Resistance ratio calculations from LC50 value in resistant populations relative to the LC50 for the laboratory susceptible strain allowed resistance phenotypes to be assigned as either weak resistance, at 5- to 26-fold resistance relative to susceptible, or strong resistance at 95- to 127-fold relative to susceptible. This study suggests that proper resistance assessment techniques can help to determine occurrence of phosphine resistance in populations of T. castaneum and can further characterize the strength of resistance present. These data can be used to support resistance management programs that consider either cessation or modification of phosphine fumigation to control T. castaneum. © The Authors 2017. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  19. An Improved Iris Recognition Algorithm Based on Hybrid Feature and ELM

    Science.gov (United States)

    Wang, Juan

    2018-03-01

    The iris image is easily polluted by noise and uneven light. This paper proposed an improved extreme learning machine (ELM) based iris recognition algorithm with hybrid feature. 2D-Gabor filters and GLCM is employed to generate a multi-granularity hybrid feature vector. 2D-Gabor filter and GLCM feature work for capturing low-intermediate frequency and high frequency texture information, respectively. Finally, we utilize extreme learning machine for iris recognition. Experimental results reveal our proposed ELM based multi-granularity iris recognition algorithm (ELM-MGIR) has higher accuracy of 99.86%, and lower EER of 0.12% under the premise of real-time performance. The proposed ELM-MGIR algorithm outperforms other mainstream iris recognition algorithms.

  20. Effects of elm bark extracts from Ulmus laevis on human chorion carcinoma cell lines.

    Science.gov (United States)

    Hartmann, Anna-Maria; Abarzua, Sibylle; Schlichting, André; Richter, Dagmar-Ulrike; Leinweber, Peter; Briese, Volker

    2011-11-01

    The potential of substances from elm bark extracts to affect cancer has been described in several studies. In this study, the anticancer effects of extracts from Ulmus laevis bark were tested in hormone-dependent gynecological tumours using human chorion carcinoma cell lines. The molecular-chemical composition of the bark extract was analysed by pyrolysis-field ionisation mass spectrometry. The influence of the extracts was determined on cell vitality and cytotoxicity in the human chorion carcinoma cell lines Jeg3 and BeWo in comparison with primary trophoblast cells. The elm bark extract was mainly composed of triterpenes, phytosterols, free fatty acids and suberins with lower amounts of dilignols and lipids. The elm bark extract significantly inhibited the vitality of Jeg3 and BeWo cells but increased the vitality of primary trophoblast cells. Substances extracted from elm bark might have beneficial effects for the prevention of hormone-dependent tumours.

  1. Distance Based Multiple Kernel ELM: A Fast Multiple Kernel Learning Approach

    Directory of Open Access Journals (Sweden)

    Chengzhang Zhu

    2015-01-01

    Full Text Available We propose a distance based multiple kernel extreme learning machine (DBMK-ELM, which provides a two-stage multiple kernel learning approach with high efficiency. Specifically, DBMK-ELM first projects multiple kernels into a new space, in which new instances are reconstructed based on the distance of different sample labels. Subsequently, an l2-norm regularization least square, in which the normal vector corresponds to the kernel weights of a new kernel, is trained based on these new instances. After that, the new kernel is utilized to train and test extreme learning machine (ELM. Extensive experimental results demonstrate the superior performance of the proposed DBMK-ELM in terms of the accuracy and the computational cost.

  2. Is cardiovascular disease in patients with diabetes associated with serum levels of MMP-2, LOX, and the elastin degradation products ELM and ELM-2?

    DEFF Research Database (Denmark)

    Rørdam Preil, Simone; Faarvang Thorsen, Anne-Sofie; Christiansen, Anne Lindegaard

    2017-01-01

    RNA-expression in diabetic patients, namely matrix metalloproteinase 2 (MMP-2), lysyl oxidase (LOX) and elastin itself. In this study we investigate whether the serum concentrations of elastin-related proteins correlate to signs of CVD in patients with T2DM. METHODS: Blood samples from 302 type 2 diabetic patients were...... analysed for MMP-2, LOX, and the elastin degradation products ELM and ELM2. The results were investigated for correlations to signs of CVD in different vascular territories, as determined by myocardial perfusion scintigraphy, carotid artery thickness and ankle-brachial blood pressure index. RESULTS: T2DM...... patients with peripheral arterial disease (low ankle-brachial index) (PAD) display higher levels of MMP-2 and ELM compared to patients without PAD. However, none of the proteins or degradation products correlated with myocardial ischemia or a combined measure of CVD-signs, including myocardial ischemia...

  3. Type I ELM filament heat fluxes on the KSTAR main chamber wall

    Directory of Open Access Journals (Sweden)

    M.-K. Bae

    2017-08-01

    Full Text Available Heat loads deposited on the first wall by mitigated Type I ELMs are expected to be the dominant contributor to the total thermal plasma wall load of the International Thermonuclear Experimental Reactor (ITER, particularly in the upper main chamber regions during the baseline H-mode magnetic equilibrium, due to the fast radial convective heat propagation of ELM filaments before complete loss to the divertor. Specific Type I ELMing H-mode discharges have been performed with a lower single null magnetic geometry, where the outboard separatrix position is slowly (∼7s scanned over a radial distance of 7cm, reducing the wall probe–separatrix distance to a minimum of ∼9cm, and allowing the ELM filament heat loss to the wall to be analyzed as a function of radial propagation distance. A fast reciprocating probe (FRP head is separately held at fixed position toroidally close and 4.7cm radially in front of the wall probe. This FRP monitors the ELM ion fluxes, allowing an average filament radial propagation speed, found to be independent of ELM energy, of 80–100ms−1 to be extracted. Radial dependence of the peak filament wall parallel heat flux is observed to be exponential, with the decay length of λq, ELM ∼25 ± 4mm and with the heat flux of q∥, ELM= 0.05MWm−2 at the wall, corresponding to q∥ ∼ 7.5MWm−2 at the second separatrix. Along with the measured radial propagation speed and the calculated radial profile of the magnetic connection lengths across the SOL, these data could be utilized to analyze filament energy loss model for the future machines.

  4. Adaptive Control of Nonlinear Discrete-Time Systems by Using OS-ELM Neural Networks

    Directory of Open Access Journals (Sweden)

    Xiao-Li Li

    2014-01-01

    Full Text Available As a kind of novel feedforward neural network with single hidden layer, ELM (extreme learning machine neural networks are studied for the identification and control of nonlinear dynamic systems. The property of simple structure and fast convergence of ELM can be shown clearly. In this paper, we are interested in adaptive control of nonlinear dynamic plants by using OS-ELM (online sequential extreme learning machine neural networks. Based on data scope division, the problem that training process of ELM neural network is sensitive to the initial training data is also solved. According to the output range of the controlled plant, the data corresponding to this range will be used to initialize ELM. Furthermore, due to the drawback of conventional adaptive control, when the OS-ELM neural network is used for adaptive control of the system with jumping parameters, the topological structure of the neural network can be adjusted dynamically by using multiple model switching strategy, and an MMAC (multiple model adaptive control will be used to improve the control performance. Simulation results are included to complement the theoretical results.

  5. Utilizing solid impurity granules for ELM pacing in NSTX-U

    Science.gov (United States)

    Lunsford, Robert; Roquemore, L.; Jaworski, M. A.; Kaita, R.; Maingi, R.; NSTX-U Team

    2015-11-01

    Periodic edge localized modes (ELMs) rapidly transport stored energy from the edge plasma to the divertor. These events result in abrupt heating of the plasma facing components (PFCs) which reduces their effective lifetime as well as generating a strong impurity influx. If the frequency of these ELMs can be increased through controlled triggering, also known as pacing, then the inverse relationship between the peak heat flux and the frequency of the ELMs can be utilized to prevent material damage that could result from otherwise unmitigated ELMs. At NSTX, the ability of small (300 - 1000 micron) impurity granules to trigger and pace these ELMs is being explored. In these experiments, ELMs are triggered by seeding a density perturbation within the edge-pedestal region through low speed injection and ablation of impurity granules, thus generating a localized instability. Granules are dropped from a reservoir and transit a vertical flight tube at which point a rotating impeller imparts horizontal momentum into the falling granules. This drives them into the edge of the discharge at speeds ranging from 50-150 m/s and average injection frequencies of up to 200 Hz depending upon the settings of the injector. Results from the initial laboratory injection tests of lithium, boron carbide (B4C) and vitreous carbon granules and their subsequent implementation in NSTX-U experiments will be discussed. Work supported by DOE Contract No. DE-AC02-09CH11466.

  6. Surface EMG signals based motion intent recognition using multi-layer ELM

    Science.gov (United States)

    Wang, Jianhui; Qi, Lin; Wang, Xiao

    2017-11-01

    The upper-limb rehabilitation robot is regard as a useful tool to help patients with hemiplegic to do repetitive exercise. The surface electromyography (sEMG) contains motion information as the electric signals are generated and related to nerve-muscle motion. These sEMG signals, representing human's intentions of active motions, are introduced into the rehabilitation robot system to recognize upper-limb movements. Traditionally, the feature extraction is an indispensable part of drawing significant information from original signals, which is a tedious task requiring rich and related experience. This paper employs a deep learning scheme to extract the internal features of the sEMG signals using an advanced Extreme Learning Machine based auto-encoder (ELMAE). The mathematical information contained in the multi-layer structure of the ELM-AE is used as the high-level representation of the internal features of the sEMG signals, and thus a simple ELM can post-process the extracted features, formulating the entire multi-layer ELM (ML-ELM) algorithm. The method is employed for the sEMG based neural intentions recognition afterwards. The case studies show the adopted deep learning algorithm (ELM-AE) is capable of yielding higher classification accuracy compared to the Principle Component Analysis (PCA) scheme in 5 different types of upper-limb motions. This indicates the effectiveness and the learning capability of the ML-ELM in such motion intent recognition applications.

  7. Identification of maturity of cuiguan pear based on RobustICA and PSO-ELM

    Science.gov (United States)

    Zhang, Yu; Huang, Yongmei; Lin, Min; Liu, Huijun; Zhou, Xinqi

    2017-08-01

    In order to improve the stability of extreme learning machine (ELM), it was proposed to use the combination of robust independent component analysis (RobustICA) and particle swarm optimization ELM algorithm. It was applied to identify the maturity of cuiguan pear at different growing periods. First the two order derivative and the discrete wavelet transform were adopted to remove the background noise and compression spectra. Then RobustICA was used to decompose the spectra to extract independent components and mixed coefficient matrices. Finally, by using particle swarm optimization, the best input layer weight and hidden layer deviation were obtained and adjusted the number of hidden layer nodes to get the best ELM model to differentiate maturity. The method was used to identify the maturity of cuiguan pear at four different stages, and has strong robustness. The results showed that RobustICA-PSO-ELM had better discrimination ability compared with RobustICA - ELM and ELM, and the accuracy increases from 75% to 94.4%.

  8. Non-linear MHD simulations of pellet triggered ELM for ITER plasma scenarios

    Science.gov (United States)

    Futatani, Shimpei; Huijsmans, Guido; Loarte, Alberto; Mantsinen, Mervi; Pamela, Stanislas; Garzotti, Luca

    2017-10-01

    The non-linear MHD simulations with the JOREK code have been performed to study the dependence of the pellet size required to trigger an ELM in ITER plasma, and also the dependency of the threshold on the pedestal plasma pressure when the pellet is injected. Based on the observation that the pedestal pressure leading to spontaneous ELM triggering is 150 kPa by JOREK simulation, pedestal pressure of 75 kPa and 112.5 kPa have been studied. The JOREK simulation results show that it is necessary to increase the pellet size by a factor of 1.5 of the number of particles in the pellet to trigger ELMs for a pedestal pressure of 75 kPa compared to 112.5 kPa in ITER 15MA/5.3T plasma. In these simulations it has also been found that the magnitude of the ELM energy loss is strongly correlated with the pedestal plasma pressure rather than with the size of the pellet that is required for triggering. The JOREK simulation shows the toroidally asymmetric profile of the heat flux on the outer divertor target due to the pellet triggered ELM which is consistent with the experiment observation of JET. The work contributes the estimation of the requirement of the pellet injection condition to control ELMs in ITER 15MA operation scenarios. The views and opinions expressed herein do not necessarily reflect either those of the European Commission or those of the ITER Organization.

  9. Effect of Island Overlap on ELM Suppression by Resonant Magnetic Perturbations in DIII-D

    Energy Technology Data Exchange (ETDEWEB)

    Fenstermacher, M E; Evans, T E; Osborne, T H; Schaffer, M J; Aldan, M P; deGrassie, J S; Gohil, P; Joseph, I; Moyer, R A; Snyder, P B; Groebner, R J; Jakubowski, M; Leonard, A W; Schmitz, O

    2007-11-08

    Recent DIII-D [J.L. Luxon, et al., Nucl. Fusion 43, 1813 (2003)] experiments show a correlation between the extent of overlap of magnetic islands induced in the edge plasma by perturbation coils and complete suppression of Type-I edge localized modes (ELMs) in plasmas with ITER-like electron pedestal collisionality {nu}*{sub e} {approx} 0.1, flux surface shape and low edge safety factor (q{sub 95} {approx} 3.6). With fixed n = 3 resonant magnetic perturbation (RMP) strength, ELM suppression is obtained only in a finite window in the edge safety factor (q{sub 95}) consistent with maximizing the resonant component of the applied helical field. ELM suppression is obtained over an increasing range of q{sub 95} by either increasing the n = 3 RMP strength, or by adding n = 1 perturbations to 'fill in' gaps between islands across the edge plasma. The suppression of Type-I ELMs correlates with a minimum width of the edge region having magnetic islands with Chirikov parameter >1.0, based on vacuum calculations of RMP mode components excluding the plasma response or rotational shielding. The fraction of vacuum magnetic field lines that are lost from the plasma, with connection length to the divertor targets comparable to an electron-ion collisional mean free path, increases throughout the island overlap region in the ELM suppressed case compared with the ELMing case.

  10. Comparison of MHD simulation codes for understanding nonlinear ELMs dynamics in KSTAR H-mode plasma

    Science.gov (United States)

    Kim, M.; Lee, J.; Park, H. K.; Yun, G. S.; Xu, X.; Jardin, S. C.; Becoulet, M.

    2017-10-01

    KSTAR electron cyclotron emission imaging (ECEI) systems have contributed to understanding the fundamental physics of ELMs by high-quality 2D and quasi-3D images of ELMs. However, in the highly nonlinear phase of ELM dynamics, the interpretation of ECE signals becomes complicated intrinsically. Theoretical and numerical approaches are necessary to enhance the understanding of ELM physics. Well-established MHD codes (BOUT + + , JOREK, and M3D-C1) are introduced for comparative study with the observations. The nonlinear solutions are obtained using the same equilibrium of the KSTAR H-mode plasma. Each code shows the partial difference in mode evolution, probably, due to the difference in optimized operation window of initial conditions. The nonlinear simulation results show that low- n (n qualitatively matches with the recent ECEI observation just before ELM-crash, or excitation of non-modal solitary perturbation (typically, n = 1) which is highly localized in poloidal and toroidal. Regardless of differences in details, qualitative similarity can provide inspiration to understand the triggering of ELM-crash. This work is supported by NRF of Korea under Contract No. NRF-2014M1A7A1A03029865.

  11. ELM elimination with Li powder injection in EAST discharges using the tungsten upper divertor

    Science.gov (United States)

    Maingi, R.; Hu, J. S.; Sun, Z.; Tritz, K.; Zuo, G. Z.; Xu, W.; Huang, M.; Meng, X. C.; Canik, J. M.; Diallo, A.; Lunsford, R.; Mansfield, D. K.; Osborne, T. H.; Gong, X. Z.; Wang, Y. F.; Li, Y. Y.; EAST team

    2018-02-01

    We report the first successful use of lithium (Li) to eliminate edge-localized modes (ELMs) with tungsten divertor plasma-facing components in the EAST device. Li powder injected into the scrape-off layer of the tungsten upper divertor successfully eliminated ELMs for 3–5 s in EAST. The ELM elimination became progressively more effective in consecutive discharges at constant lithium delivery rates, and the divertor D α baseline emission was reduced, both signatures of improved wall conditioning. A modest decrease in stored energy and normalized energy confinement was also observed, but the confinement relative to H98 remained well above 1, extending the previous ELM elimination results via Li injection into the lower carbon divertor in EAST (Hu et al 2015 Phys. Rev. Lett. 114 055001). These results can be compared with recent observations with lithium pellets in ASDEX-Upgrade that failed to mitigate ELMs (Lang et al 2017 Nucl. Fusion 57 016030), highlighting one comparative advantage of continuous powder injection for real-time ELM elimination.

  12. White pine blister rust resistance in North American, Asian and european species - results from artificial inoculartion trials in Oregon

    Directory of Open Access Journals (Sweden)

    R.A. Sniezko

    2013-12-01

    Full Text Available Dorena Genetic Resource Center (DGRC has used artificial inoculation trials to evaluate progenies of thousands of Pinus monticola and P. lambertiana selections from Oregon and Washington for resistance to white pine blister rust caused by Cronartium ribicola. In addition, early results are now available for P. albicaulis and P. strobiformis. DGRC has also recently evaluated seed orchard progenies of P. strobus, as well as bulked seedlots from P. armandii and P. peuce. The majority of P. monticola, P. lambertiana, P. albicaulis, and P. strobus progenies are very susceptible to blister rust. However, resistance exists in all these species. P. strobiformis showed relatively high levels of resistance for the eight progenies tested. Resistance in P. armandii was mainly reflected in the very low percentage of cankered seedlings; for P. peuce, the high percentage of cankered seedlings alive three years after inoculation was notable. R-genes are present in some of the North American five-needle pine species, but partial resistance traits (e.g. bark reaction will play a major role in breeding activities for P. monticola and P. lambertiana and will likely be the key to developing durable resistance.

  13. Draft Genome Sequences of Two Extensively Drug-Resistant Strains of Mycobacterium tuberculosis Belonging to the Euro-American S Lineage

    NARCIS (Netherlands)

    Malinga, L.A.; Abeel, T.; Desjardins, C.A.; Dlamini, T.C.; Cassell, G.; Chapman, S.B.; Birren, B.W.; Earl, A.M.; Van der Walt, M.

    2016-01-01

    We report the whole-genome sequencing of two extensively drug-resistant tuberculosis strains belonging to the Euro-American S lineage. The RSA 114 strain showed single-nucleotide polymorphisms predicted to have drug efflux activity.

  14. Fighting through Resistance: Challenges Faced by African American Women Principals in Predominately White School Settings

    Science.gov (United States)

    Jackson, Alicia D.

    2013-01-01

    African American women represented a growing proportion within the field of education in attaining leadership roles as school principals. As the numbers continued to rise slowly, African American women principals found themselves leading in diverse or even predominately White school settings. Leading in such settings encouraged African American…

  15. Beyond independence: Anti-Americanism and the Serb resistance in Kosova

    OpenAIRE

    MA. Përparim Gutaj

    2013-01-01

    This paper examines the Serb resistance in northern Kosova. A number of studies, over the last decade, have been performed that scrutinize the case of Kosova and look into the strained relations between Kosova Albanians and Kosova Serbs. Yet, no study has been carried out to explain the Serb resistance, and more importantly, its nature and its underpinning mechanisms. This paper intends to just that. The central argument it makes is that the Serb resistance in northern Kosova is a Serbian eli...

  16. Effects of ELMs on ITER divertor armour materials

    Science.gov (United States)

    Zhitlukhin, A.; Klimov, N.; Landman, I.; Linke, J.; Loarte, A.; Merola, M.; Podkovyrov, V.; Federici, G.; Bazylev, B.; Pestchanyi, S.; Safronov, V.; Hirai, T.; Maynashev, V.; Levashov, V.; Muzichenko, A.

    2007-06-01

    This paper is concerned with investigation of an erosion of the ITER-like divertor plasma facing components under plasma heat loads expected during the Type I ELMs in ITER. These experiments were carried out on plasma accelerator QSPA at the SRC RF TRINITI under EU/RF collaboration. Targets were exposed by series repeated plasma pulses with heat loads in a range of 0.5-1.5 MJ/m2 and pulse duration 0.5 ms. Erosion of CFC macrobrushes was determined mainly by sublimation of PAN-fibres that was less than 2.5 μm per pulse. The CFC erosion was negligible at the energy density less than 0.5 MJ/m2 and was increased to the average value 0.3 μm per pulse at 1.5 MJ/m2. The pure tungsten macrobrushes erosion was small in the energy range of 0.5-1.3 MJ/m2. The sharp growth of tungsten erosion and the intense droplet ejection were observed at the energy density of 1.5 MJ/m2.

  17. Energy saving and prediction modeling of petrochemical industries: A novel ELM based on FAHP

    International Nuclear Information System (INIS)

    Geng, ZhiQiang; Qin, Lin; Han, YongMing; Zhu, QunXiong

    2017-01-01

    Extreme learning machine (ELM), which is a simple single-hidden-layer feed-forward neural network with fast implementation, has been widely applied in many engineering fields. However, it is difficult to enhance the modeling ability of extreme learning in disposing the high-dimensional noisy data. And the predictive modeling method based on the ELM integrated fuzzy C-Means integrating analytic hierarchy process (FAHP) (FAHP-ELM) is proposed. The fuzzy C-Means algorithm is used to cluster the input attributes of the high-dimensional data. The Analytic Hierarchy Process (AHP) based on the entropy weights is proposed to filter the redundant information and extracts characteristic components. Then, the fusion data is used as the input of the ELM. Compared with the back-propagation (BP) neural network and the ELM, the proposed model has better performance in terms of the speed of convergence, generalization and modeling accuracy based on University of California Irvine (UCI) benchmark datasets. Finally, the proposed method was applied to build the energy saving and predictive model of the purified terephthalic acid (PTA) solvent system and the ethylene production system. The experimental results demonstrated the validity of the proposed method. Meanwhile, it could enhance the efficiency of energy utilization and achieve energy conservation and emission reduction. - Highlights: • The ELM integrated FAHP approach is proposed. • The FAHP-ELM prediction model is effectively verified through UCI datasets. • The energy saving and prediction model of petrochemical industries is obtained. • The method is efficient in improvement of energy efficiency and emission reduction.

  18. Pruning The ELM Survey: Characterizing Candidate Low-mass White Dwarfs through Photometric Variability

    Science.gov (United States)

    Bell, Keaton J.; Gianninas, A.; Hermes, J. J.; Winget, D. E.; Kilic, Mukremin; Montgomery, M. H.; Castanheira, B. G.; Vanderbosch, Z.; Winget, K. I.; Brown, Warren R.

    2017-02-01

    We assess the photometric variability of nine stars with spectroscopic Teff and log g values from the ELM Survey that locates them near the empirical extremely low-mass (ELM) white dwarf instability strip. We discover three new pulsating stars: SDSS J135512.34+195645.4, SDSS J173521.69+213440.6, and SDSS J213907.42+222708.9. However, these are among the few ELM Survey objects that do not show radial velocity (RV) variations that confirm the binary nature expected of helium-core white dwarfs. The dominant 4.31 hr pulsation in SDSS J135512.34+195645.4 far exceeds the theoretical cut-off for surface reflection in a white dwarf, and this target is likely a high-amplitude δ Scuti pulsator with an overestimated surface gravity. We estimate the probability to be less than 0.0008 that the lack of measured RV variations in four of eight other pulsating candidate ELM white dwarfs could be due to low orbital inclination. Two other targets exhibit variability as photometric binaries. Partial coverage of the 19.342 hr orbit of WD J030818.19+514011.5 reveals deep eclipses that imply a primary radius >0.4 R⊙—too large to be consistent with an ELM white dwarf. The only object for which our time series photometry adds support to ELM white dwarf classification is SDSS J105435.78-212155.9, which has consistent signatures of Doppler beaming and ellipsoidal variations. We conclude that the ELM Survey contains multiple false positives from another stellar population at Teff ≲ 9000 K, possibly related to the sdA stars recently reported from SDSS spectra.

  19. Assessment of erosion of the ITER divertor targets during type I ELMs

    International Nuclear Information System (INIS)

    Federici, G; Loarte, A; Strohmayer, G

    2003-01-01

    This paper presents the results of a preliminary assessment conducted to estimate the thermal response and erosion lifetime of the ITER divertor targets clad either with carbon-fibre composite or tungsten during type I ELMs. The one-dimensional thermal/erosion model, used for the analyses, is briefly described. It includes all the key surface heat transfer processes such as evaporation, melting, and radiation, and their interaction with the bulk thermal response, and it is based on an implicit finite-difference scheme, which allows for temperature-dependent material properties. The cases analysed clarify the influence of several ELM parameters on the heat transfer and erosion processes at the target (i.e. characteristic plasma ELM energy loss from the pedestal, fraction of the energy reaching the divertor, broadening of the strike-points during ELMs, duration and waveform of the ELM heat load) and design/material parameters (i.e. inclination of the target, type and thickness of the armour material, and for tungsten only, fraction of the melt layer loss). Comparison is made between cases where all ELMs are characterized by the same fixed averaged parameters, and cases where instead the characteristic parameters of each ELM are evaluated in a random fashion by using a standard Monte Carlo technique, based on distributions of some of the variables of interest derived from experiments in today's machines. Although uncertainties rule out providing firm quantitative predictions, the results of this study are useful to illustrate trends. Based on the results, the implications on the design and operation are discussed and priorities are determined for the R and D needed to reduce the remaining uncertainties

  20. H-Mode Turbulence, Power Threshold, ELM, and Pedestal Studies in NSTX

    International Nuclear Information System (INIS)

    Maingi, R.; Bush, C.E.; Fredrickson, E.D.; Gates, D.A.; Kaye, S.M.; LeBlanc, B.P.; Menard, J.E.; Meyer, H.; Mueller, D.; Nishino, N.; Roquemore, A.L.; Sabbagh, S.A.; Tritz, K.; Zweben, S.J.; Bell, M.G.; Bell, R.E.; Biewer, T.; Boedo, J.A.; Johnson, D.W.; Kaita, R.; Kugel, H.W.; Maqueda, R.J.; Munsat, T.; Raman, R.; Soukhanovskii, V.A.; Stevenson, T.; Stutman, D.

    2004-01-01

    High-confinement mode (H-mode) operation plays a crucial role in NSTX [National Spherical Torus Experiment] research, allowing higher beta limits due to reduced plasma pressure peaking, and long-pulse operation due to high bootstrap current fraction. Here, new results are presented in the areas of edge localized modes (ELMs), H-mode pedestal physics, L-H turbulence, and power threshold studies. ELMs of several other types (as observed in conventional aspect ratio tokamaks) are often observed: (1) large, Type I ELMs, (2) ''medium'' Type II/III ELMs, and (3) giant ELMs which can reduce stored energy by up to 30% in certain conditions. In addition, many high-performance discharges in NSTX have tiny ELMs (newly termed Type V), which have some differences as compared with ELM types in the published literature. The H-mode pedestal typically contains between 25-33% of the total stored energy, and the NSTX pedestal energy agrees reasonably well with a recent international multi-machine scaling. We find that the L-H transition occurs on a ∼100 (micro)sec timescale as viewed by a gas puff imaging diagnostic, and that intermittent quiescent periods precede the final transition. A power threshold identity experiment between NSTX and MAST shows comparable loss power at the L-H transition in balanced double-null discharges. Both machines require more power for the L-H transition as the balance is shifted toward lower single null. High field side gas fueling enables more reliable H-mode access, but does not always lead to a lower power threshold e.g., with a reduction of the duration of early heating. Finally the edge plasma parameters just before the L-H transition were compared with theories of the transition. It was found that while some theories can separate well-developed L- and H-mode data, they have little predictive value

  1. Pruning The ELM Survey: Characterizing Candidate Low-mass White Dwarfs through Photometric Variability

    Energy Technology Data Exchange (ETDEWEB)

    Bell, Keaton J.; Winget, D. E.; Montgomery, M. H.; Castanheira, B. G.; Vanderbosch, Z.; Winget, K. I. [Department of Astronomy, University of Texas at Austin, Austin, TX 78712 (United States); Gianninas, A.; Kilic, Mukremin [Homer L. Dodge Department of Physics and Astronomy, University of Oklahoma, Norman, OK 73019 (United States); Hermes, J. J. [Department of Physics and Astronomy, University of North Carolina, Chapel Hill, NC 27599 (United States); Brown, Warren R., E-mail: keatonb@astro.as.utexas.edu [Smithsonian Astrophysical Observatory, Cambridge, MA 02138 (United States)

    2017-02-01

    We assess the photometric variability of nine stars with spectroscopic T {sub eff} and log g values from the ELM Survey that locates them near the empirical extremely low-mass (ELM) white dwarf instability strip. We discover three new pulsating stars: SDSS J135512.34+195645.4, SDSS J173521.69+213440.6, and SDSS J213907.42+222708.9. However, these are among the few ELM Survey objects that do not show radial velocity (RV) variations that confirm the binary nature expected of helium-core white dwarfs. The dominant 4.31 hr pulsation in SDSS J135512.34+195645.4 far exceeds the theoretical cut-off for surface reflection in a white dwarf, and this target is likely a high-amplitude δ Scuti pulsator with an overestimated surface gravity. We estimate the probability to be less than 0.0008 that the lack of measured RV variations in four of eight other pulsating candidate ELM white dwarfs could be due to low orbital inclination. Two other targets exhibit variability as photometric binaries. Partial coverage of the 19.342 hr orbit of WD J030818.19+514011.5 reveals deep eclipses that imply a primary radius >0.4 R {sub ⊙}—too large to be consistent with an ELM white dwarf. The only object for which our time series photometry adds support to ELM white dwarf classification is SDSS J105435.78−212155.9, which has consistent signatures of Doppler beaming and ellipsoidal variations. We conclude that the ELM Survey contains multiple false positives from another stellar population at T {sub eff}≲9000 K, possibly related to the sdA stars recently reported from SDSS spectra.

  2. Characterization of major lithologic units underlying the lower American River using water-borne continuous resistivity profiling, Sacramento, California, June 2008

    Science.gov (United States)

    Ball, Lyndsay B.; Teeple, Andrew

    2013-01-01

    The levee system of the lower American River in Sacramento, California, is situated above a mixed lithology of alluvial deposits that range from clay to gravel. In addition, sand deposits related to hydraulic mining activities underlie the floodplain and are preferentially prone to scour during high-flow events. In contrast, sections of the American River channel have been observed to be scour resistant. In this study, the U.S. Geological Survey, in cooperation with the U.S. Army Corps of Engineers, explores the resistivity structure of the American River channel to characterize the extent and thickness of lithologic units that may impact the scour potential of the area. Likely lithologic structures are interpreted, but these interpretations are non-unique and cannot be directly related to scour potential. Additional geotechnical data would provide insightful data on the scour potential of certain lithologic units. Additional interpretation of the resistivity data with respect to these results may improve interpretations of lithology and scour potential throughout the American River channel and floodplain. Resistivity data were collected in three profiles along the American River using a water-borne continuous resistivity profiling technique. After processing and modeling these data, inverted resistivity profiles were used to make interpretations about the extent and thickness of possible lithologic units. In general, an intermittent high-resistivity layer likely indicative of sand or gravel deposits extends to a depth of around 30 feet (9 meters) and is underlain by a consistent low-resistivity layer that likely indicates a high-clay content unit that extends below the depth of investigation (60 feet or 18 meters). Immediately upstream of the Watt Avenue Bridge, the high-resistivity layer is absent, and the low-resistivity layer extends to the surface where a scour-resistant layer has been previously observed in the river bed.

  3. Phosphine Resistance in North American Field Populations of the Lesser Grain Borer, Rhyzopertha dominica (Coleoptera: Bostrichidae).

    Science.gov (United States)

    Afful, E; Elliott, Brent; Nayak, Manoj K; Phillips, Thomas W

    2018-02-09

    Phosphine is the most widely used fumigant for stored grain insect pests, and resistance to phosphine has evolved in several species worldwide. This study was designed to determine the presence of phosphine resistance in 34 populations of Rhyzopertha dominica (F.) collected from the United States and Canada. Adult R. dominica were sampled and subjected to a discriminatory dose toxicity assay of exposure to 20 ppm of phosphine for 20 h of exposure to distinguish a susceptible R. dominica adult by death from a resistant beetle that survives the treatment. All but two of the 34 geographic populations surveyed had some beetles that were resistant to phosphine, and the frequency of resistance varied from 97% in a population from Parlier, California to 0% in beetles from both Carnduff, Saskatchewan and Starbuck, Manitoba. Probit analyses of dose-mortality bioassays with beetles from a laboratory-susceptible strain and those from five of the populations sampled were used to calculate resistance ratio factors (RRs) based on the ratio of LC50 (estimate for the concentration to kill 50% of a test group) in the sampled population to the LC50 for the susceptible strain. The highest RR for the five resistant populations was nearly 596-fold in beetles from Belle Glade, Florida, whereas the lowest RR in that group was 9-fold in Wamego, Kansas. This study revealed that phosphine resistance in R. dominica is common across North America and some populations have levels of resistance that may pose challenges for continued use of phosphine for their management. © The Author(s) 2017. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  4. Genetic diversity and relationships among Dutch elm disease tolerant Ulmus pumila L. accessions from China.

    Science.gov (United States)

    Zalapa, Juan E; Brunet, Johanne; Guries, Raymond P

    2008-07-01

    Elm breeding programs worldwide have relied heavily on Asian elm germplasm, particularly Ulmus pumila, for the breeding of Dutch elm disease tolerant cultivars. However, the extent and patterning of genetic variation in Asian elm species is unknown. Therefore, the objective of this research was to determine the extent of genetic diversity among 53 U. pumila accessions collected throughout the People's Republic of China. Using 23 microsatellite loci recently developed in the genus Ulmus, a total of 94 alleles were identified in 15 polymorphic and 4 monomorphic loci. The average number of alleles per locus was 4.9, with a range of 1-11 alleles. Gene diversity estimates per locus ranged from 0.08 to 0.87, and the non-exclusion probability for the 15 polymorphic loci combined was 0.7 x 10(-9). Nineteen region-specific alleles were identified, and regional gene diversity estimates were moderately high (0.48-0.57). The genetic relationships among accessions and regions were estimated by UPGMA and principal coordinate analysis. Both techniques discriminated all accessions and regions. Two microsatellite markers (UR175 + UR123 or Ulm-3) were sufficient to discriminate up to 99.7% of the accessions studied. This research provides useful information for DNA-based fingerprinting, breeding, ecological studies, and diversity assessment of elm germplasm.

  5. Observation of pre- and postcursor modes of type-I ELMs on JET

    International Nuclear Information System (INIS)

    Koslowski, H.R.; Perez, C.; Alper, B.; Hender, T.C.; Sharapov, S.E.; Eich, T.; Huysmans, G.T.A.; Smeulders, P.; Westerhof, E.

    2003-01-01

    Recent observations of MHD activity in type-I ELMy H-mode discharges on JET have revealed two phenomena: (i) the so-called palm tree mode, a new, snake-like MHD mode at the q = 3 surface which is excited by type-I ELMs, and (ii) coherent MHD mode activity as a precursor to the ELM collapse. Both modes are detected by magnetic pick up coils and can also be seen on the edge ECE and SXR measurements. They are located a few cm inside the separatrix. Palm tree modes have been identified in a wide range of plasma conditions, which comprise standard ELMy H-modes, ITER-like plasma shapes, pellet fuelling, and even pure helium plasmas. The mode frequency increases in time and starts to saturate until the mode finally decays. A possible explanation of the palm tree mode is, that it is the remnant of a (3,1)-island created due to edge ergodisation by the ELM perturbation. The type-I ELM precursor modes have toroidal mode numbers n in the range 1 to 14, a kink-like structure, and appear commonly 0.5 - 1 ms before the ELM, but can appear much earlier in some cases. (author)

  6. A stationary long-pulse ELM-absent H-mode regime in EAST

    Science.gov (United States)

    Ye, Y.; Xu, G. S.; Wan, B. N.; Chen, R.; Yan, N.; Guo, H. Y.; Shao, L. M.; Yang, Q. Q.; Wang, H. Q.; Zhang, W.; Xia, T. Y.; Zhang, T.; Li, Y. Y.; Wang, T. F.; Zang, Q.; Hu, Y. J.; Wu, G. J.; Zhang, L.; Hao, B. L.; Wang, L.; Li, Y. L.; Wu, X. Q.; Chen, L.; Lan, H.; Wang, Y. F.; Xu, J. C.; Hu, G. H.; Ding, S. Y.; Zhang, H.; Zhao, N.; Li, J.; The EAST Team

    2017-08-01

    A stationary edge-localized mode (ELM)-absent H-mode regime, with an electrostatic edge coherent mode (ECM) which resides in the pedestal region, has been achieved in the EAST tokamak recently. This regime allows the operation of a nearly fully noninductive long pulse (>15 s), exhibiting a relatively high pedestal and good global energy confinement with {{H}98,y2} near 1.2, and excellent impurity control. Furthermore, this regime is mostly obtained with a 4.6 GHz lower hybrid current drive (LHCD) or counter-current neutral beam injection (NBI), plus electron cyclotron resonance heating, and an extensive lithium wall coating. This stationary ELM-absent H-mode regime transits to a stationary small ELM H-mode regime, and upon additional heating power from the 2.45 GHz LHCD, an ion cyclotron resonant frequency or co-current NBI is applied (under 4.6 GHz LHCD heating background). A slight change of the plasma configuration also makes the small ELMs reappear. The experimental observations suggest that a long-pulse ELM-absent regime can be induced by the ECM, which exhibits strong electrostatic fluctuations and may provide a channel for continuous particle (especially impurities) and heat exhaust across the pedestal. The ECM exists in the collisionality of ν e*   =  2.5-4 and the pressure gradient |\

  7. ELM Behavior in High- βp EAST-Demonstration Plasmas on DIII-D

    Science.gov (United States)

    Li, G. Q.; Gong, X. Z.; Garofalo, A. M.; Lao, L. L.; Meneghini, O.; Snyder, P. B.; Ren, Q. L.; Ding, S. Y.; Guo, W. F.; Qian, J. P.; Wan, B. N.; Xu, G. S.; Holcomb, C. T.; Solomon, W. M.

    2015-11-01

    In the DIII-D high- βp EAST-demonstration experiment, for several similar discharges when the experimental parameters such as the toroidal magnetic field or ECH power are varied slightly, the changes in ELM frequency response are observed to be much larger. Kinetic EFIT equilibrium reconstructions for these discharges have been performed, which suggest that the ELM frequency changes are likely due to the variations of pedestal width, height, and edge current density. Kinetic profile analyses further indicate that the strong ITB that are located at large minor radii (rho=0.6 ~0.7) in these discharges are affecting the pedestal structure. The ITB could broaden the pedestal width and decrease the pedestal height, thus changing the ELM frequency and size. With the GATO and ELITE MHD codes, the linear growth rates and mode structures of these ELMs are analyzed. The impact of ITB on the ELMs behavior will be discussed. Work supported by China MOST under 2014GB106001 and 2015GB102001 and US DOE under DE-FC02-04ER54698 and DE-FG03-95ER54309.

  8. Nonlinear simulation of ELM dynamics in the presence of resonant magnetic perturbations

    Science.gov (United States)

    Chandra, D.; Thyagaraja, A.; Sen, A.; Kaw, P.

    2017-07-01

    We report on nonlinear simulation studies on the dynamical behaviour of ELMs under the influence of resonant magnetic perturbations (RMPs) using a two-fluid initial value electromagnetic nonlinear global code (CUTIE). To simulate ELMs we introduce a particle source in the confinement region and a particle sink in the edge region. To study ELM control using RMPs we have applied an n  =  2 static external magnetic perturbation at the edge and made detailed parametric studies under varying conditions for the machine and plasma parameters typical of COMPASS-D. Our results show that ELM mitigation is possible for RMP powers beyond a specific threshold. The results also provide valuable insights into the RMP induced modifications of the complex nonlinear dynamics of the ELMs, in particular on the redistribution of mode energy and the cascading of energy to shorter scale lengths. We also observe a hysteresis in states as we increase the amplitude of RMPs and then decrease it to the same value.

  9. Plasmid-mediated resistance to cephalosporins and quinolones in Escherichia coli from American crows in the USA.

    Science.gov (United States)

    Jamborova, Ivana; Dolejska, Monika; Zurek, Ludek; Townsend, Andrea K; Clark, Anne B; Ellis, Julie C; Papousek, Ivo; Cizek, Alois; Literak, Ivan

    2017-05-01

    American crow (Corvus brachyrhynchos) faeces were tested for Escherichia coli with plasmid-mediated quinolone resistance (PMQR), extended-spectrum beta-lactamases (ESBL) and AmpC beta-lactamases. A total of 590 faecal samples were collected at four roosting sites in the USA and cultivated on selective media. Pulsed-field gel electrophoresis (PFGE) and multi-locus sequence typing (MLST) were performed to assess clonality. Transferability of resistance genes was studied using conjugation and transformation bioassays. In total, 78 (13%, n = 590) cefotaxime-resistant isolates were obtained, of which 66 and 12 displayed AmpC and ESBL phenotypes, respectively. Fifty-four AmpC-producing isolates carried bla CMY-2 . Isolates producing ESBLs contained genes bla CTX-M-27 (5 isolates), bla CTX-M-15 (4), bla CTX-M-14 (2) and bla CTX-M-1 (1). Ninety isolates (15%, n = 590) with reduced susceptibility to ciprofloxacin were obtained, among which 14 harboured PMQR genes aac(6')-Ib-cr (4 isolates), qnrB19 (3), qnrS1 (2), qnrA1 (2), qnrB2 (1), qnrB6 (1) and qnrD3 (1). High genetic diversity was revealed by PFGE and MLST. Epidemiologically important E. coli clones (e.g., ST131, ST405) were identified. Plasmids carrying bla CMY-2 were assigned predominantly to IncA/C (8 plasmids), IncI1/ST23 (5) and IncI1/ST12 (3). The study demonstrates a widespread occurrence of E. coli with ESBL, AmpC and PMQR genes associated with clinically important multidrug-resistant clones and epidemic plasmids, in American crows. © 2017 Society for Applied Microbiology and John Wiley & Sons Ltd.

  10. Integrated simulations of H-mode operation in ITER including core fuelling, divertor detachment and ELM control

    Science.gov (United States)

    Polevoi, A. R.; Loarte, A.; Dux, R.; Eich, T.; Fable, E.; Coster, D.; Maruyama, S.; Medvedev, S. Yu.; Köchl, F.; Zhogolev, V. E.

    2018-05-01

    ELM mitigation to avoid melting of the tungsten (W) divertor is one of the main factors affecting plasma fuelling and detachment control at full current for high Q operation in ITER. Here we derive the ITER operational space, where ELM mitigation to avoid melting of the W divertor monoblocks top surface is not required and appropriate control of W sources and radiation in the main plasma can be ensured through ELM control by pellet pacing. We apply the experimental scaling that relates the maximum ELM energy density deposited at the divertor with the pedestal parameters and this eliminates the uncertainty related with the ELM wetted area for energy deposition at the divertor and enables the definition of the ITER operating space through global plasma parameters. Our evaluation is thus based on this empirical scaling for ELM power loads together with the scaling for the pedestal pressure limit based on predictions from stability codes. In particular, our analysis has revealed that for the pedestal pressure predicted by the EPED1  +  SOLPS scaling, ELM mitigation to avoid melting of the W divertor monoblocks top surface may not be required for 2.65 T H-modes with normalized pedestal densities (to the Greenwald limit) larger than 0.5 to a level of current of 6.5–7.5 MA, which depends on assumptions on the divertor power flux during ELMs and between ELMs that expand the range of experimental uncertainties. The pellet and gas fuelling requirements compatible with control of plasma detachment, core plasma tungsten accumulation and H-mode operation (including post-ELM W transient radiation) have been assessed by 1.5D transport simulations for a range of assumptions regarding W re-deposition at the divertor including the most conservative assumption of zero prompt re-deposition. With such conservative assumptions, the post-ELM W transient radiation imposes a very stringent limit on ELM energy losses and the associated minimum required ELM frequency. Depending on

  11. Brief report: Contextual predictors of African American adolescents' ethnic-racial identity affirmation-belonging and resistance to peer pressure.

    Science.gov (United States)

    Derlan, Chelsea L; Umaña-Taylor, Adriana J

    2015-06-01

    The current study examined whether contextual factors (i.e., familial cultural socialization, percentage of same-ethnicity friends in high school, and neighborhood ethnic-racial composition) predicted ethnic-racial identity affirmation-belonging and, in turn, resistance to peer pressure to engage in problem behavior. Participants were 250 African American adolescents (M age = 15.57 years; SD = 1.22). Consistent with ecological theory, findings indicated that familial cultural socialization and percentage of same-ethnicity friends predicted greater ethnic-racial identity affirmation-belonging. Furthermore, consistent with notions from social identity theory, youth who reported higher ethnic-racial identity affirmation-belonging also reported greater resistance to peer pressure. Findings highlight the significance of the family and school context, as well as the importance of ethnic-racial identity affirmation-belonging, for African American youths' positive development. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  12. Analytical Redundancy Design for Aeroengine Sensor Fault Diagnostics Based on SROS-ELM

    Directory of Open Access Journals (Sweden)

    Jun Zhou

    2016-01-01

    Full Text Available Analytical redundancy technique is of great importance to guarantee the reliability and safety of aircraft engine system. In this paper, a machine learning based aeroengine sensor analytical redundancy technique is developed and verified through hardware-in-the-loop (HIL simulation. The modified online sequential extreme learning machine, selective updating regularized online sequential extreme learning machine (SROS-ELM, is employed to train the model online and estimate sensor measurements. It selectively updates the output weights of neural networks according to the prediction accuracy and the norm of output weight vector, tackles the problems of singularity and ill-posedness by regularization, and adopts a dual activation function in the hidden nodes combing neural and wavelet theory to enhance prediction capability. The experimental results verify the good generalization performance of SROS-ELM and show that the developed analytical redundancy technique for aeroengine sensor fault diagnosis based on SROS-ELM is effective and feasible.

  13. Compound feature selection and parameter optimization of ELM for fault diagnosis of rolling element bearings.

    Science.gov (United States)

    Luo, Meng; Li, Chaoshun; Zhang, Xiaoyuan; Li, Ruhai; An, Xueli

    2016-11-01

    This paper proposes a hybrid system named as HGSA-ELM for fault diagnosis of rolling element bearings, in which real-valued gravitational search algorithm (RGSA) is employed to optimize the input weights and bias of ELM, and the binary-valued of GSA (BGSA) is used to select important features from a compound feature set. Three types fault features, namely time and frequency features, energy features and singular value features, are extracted to compose the compound feature set by applying ensemble empirical mode decomposition (EEMD). For fault diagnosis of a typical rolling element bearing system with 56 working condition, comparative experiments were designed to evaluate the proposed method. And results show that HGSA-ELM achieves significant high classification accuracy compared with its original version and methods in literatures. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

  14. The observation of small ELM post-cursor mode in EAST

    Science.gov (United States)

    Nan, ZHAO; Ning, YAN; Guosheng, XU; Zhengxiong, WANG; Ran, CHEN; Huiqian, WANG; Liang, WANG; Siye, DING; Linming, SHAO; Liang, CHEN; Guanghai, HU; Wei, ZHANG

    2018-02-01

    A ‘post-cursor’ quasi-coherent mode with frequency ∼50 kHz has been observed following the crash of small edge localized modes (ELMs) in the Experimental Advanced Superconducting Tokamak by using a reciprocating Langmuir probe system inserted at the outboard midplane. This mode with strong potential and magnetic perturbations propagates in the electron-diamagnetic drift direction in the laboratory frame. In addition, these quasi-coherent fluctuations appear to be modulated by a MHD mode with lower frequency (∼5 kHz). The bi-coherence analysis shows that the post-cursor mode and the MHD mode have nonlinear interaction through three-wave coupling. The understanding on post-cursor mode can enhance our knowledge of ELMs and pedestal physics, and give new insight into the ELM process itself.

  15. Enhancement of ELM by Clustering Discrimination Manifold Regularization and Multiobjective FOA for Semisupervised Classification.

    Science.gov (United States)

    Ye, Qing; Pan, Hao; Liu, Changhua

    2015-01-01

    A novel semisupervised extreme learning machine (ELM) with clustering discrimination manifold regularization (CDMR) framework named CDMR-ELM is proposed for semisupervised classification. By using unsupervised fuzzy clustering method, CDMR framework integrates clustering discrimination of both labeled and unlabeled data with twinning constraints regularization. Aiming at further improving the classification accuracy and efficiency, a new multiobjective fruit fly optimization algorithm (MOFOA) is developed to optimize crucial parameters of CDME-ELM. The proposed MOFOA is implemented with two objectives: simultaneously minimizing the number of hidden nodes and mean square error (MSE). The results of experiments on actual datasets show that the proposed semisupervised classifier can obtain better accuracy and efficiency with relatively few hidden nodes compared with other state-of-the-art classifiers.

  16. Enhancement of ELM by Clustering Discrimination Manifold Regularization and Multiobjective FOA for Semisupervised Classification

    Directory of Open Access Journals (Sweden)

    Qing Ye

    2015-01-01

    Full Text Available A novel semisupervised extreme learning machine (ELM with clustering discrimination manifold regularization (CDMR framework named CDMR-ELM is proposed for semisupervised classification. By using unsupervised fuzzy clustering method, CDMR framework integrates clustering discrimination of both labeled and unlabeled data with twinning constraints regularization. Aiming at further improving the classification accuracy and efficiency, a new multiobjective fruit fly optimization algorithm (MOFOA is developed to optimize crucial parameters of CDME-ELM. The proposed MOFOA is implemented with two objectives: simultaneously minimizing the number of hidden nodes and mean square error (MSE. The results of experiments on actual datasets show that the proposed semisupervised classifier can obtain better accuracy and efficiency with relatively few hidden nodes compared with other state-of-the-art classifiers.

  17. Pathogens of bovine respiratory disease in North American feedlots conferring multidrug resistance via integrative conjugative elements.

    Science.gov (United States)

    Klima, Cassidy L; Zaheer, Rahat; Cook, Shaun R; Booker, Calvin W; Hendrick, Steve; Alexander, Trevor W; McAllister, Tim A

    2014-02-01

    In this study, we determined the prevalence of bovine respiratory disease (BRD)-associated viral and bacterial pathogens in cattle and characterized the genetic profiles, antimicrobial susceptibilities, and nature of antimicrobial resistance determinants in collected bacteria. Nasopharyngeal swab and lung tissue samples from 68 BRD mortalities in Alberta, Canada (n = 42), Texas (n = 6), and Nebraska (n = 20) were screened using PCR for bovine viral diarrhea virus (BVDV), bovine respiratory syncytial virus, bovine herpesvirus 1, parainfluenza type 3 virus, Mycoplasma bovis, Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni. Excepting bovine herpesvirus 1, all agents were detected. M. haemolytica (91%) and BVDV (69%) were the most prevalent, with cooccurrence in 63% of the cattle. Isolates of M. haemolytica (n = 55), P. multocida (n = 8), and H. somni (n = 10) from lungs were also collected. Among M. haemolytica isolates, a clonal subpopulation (n = 8) was obtained from a Nebraskan feedlot. All three bacterial pathogens exhibited a high rate of antimicrobial resistance, with 45% exhibiting resistance to three or more antimicrobials. M. haemolytica (n = 18), P. multocida (n = 3), and H. somni (n = 3) from Texas and Nebraska possessed integrative conjugative elements (ICE) that conferred resistance for up to seven different antimicrobial classes. ICE were shown to be transferred via conjugation from P. multocida to Escherichia coli and from M. haemolytica and H. somni to P. multocida. ICE-mediated multidrug-resistant profiles of bacterial BRD pathogens could be a major detriment to many of the therapeutic antimicrobial strategies currently used to control BRD.

  18. Semiochemical-MediatedFlight Strategies of Two Invasive Elm Bark Beetles: A Potential Factor in Competitive Displacement

    Science.gov (United States)

    A recent seven-state survey revealed that the newly invasive banded elm bark beetle, Scolytus schevyrewi, was abundant in areas of Colorado and Wyoming, USA, whereas the long-established European elm bark beetle, S. multistriatus was not as abundant. Behavioral trials were conducted by hanging sm...

  19. Co-occurrence of the invasive banded and European elm bark beetles (Coleoptera: Scolytidae) in North America

    Science.gov (United States)

    Janna C. Lee; Ingrid Aguayo; Ray Aslin; Gail Durham; Shakeeb M. Hamud; Beruce D. Moltzan; A. Steve Munson; Jose F. Negron; Travis Peterson; Iral R. Ragenovich; Jeffrey J. Witcosky; Steven J. Seybold

    2009-01-01

    The invasive European elm bark beetle, Scolytus multistriatus (Marsham), was detected in Massachusetts a century ago, and it now occurs throughout the continental United States and southern Canada. The Asian banded elm bark beetle, Scolytus schevyrewi Semenov, was discovered in the United States in 2003, and now occurs in 28 states...

  20. Resistance to Phytophthora cinnamomi among seedlings from backcross families of hybrid american chestnut

    Science.gov (United States)

    Steven N. Jeffers; Inga M. Meadows; Joseph B. James; Paul H. Sisco

    2012-01-01

    American chestnut (Castanea dentata (Marsh.) Borkh.) once was a primary hardwood species in forests of the eastern United States. Sometime during the late 18th century, it is speculated that Phytophthora cinnamomi, which causes Phytophthora root rot (PRR) on many woody plant species, was introduced to the southeast region of...

  1. Resisting and Redirecting: Agentive Practices within an African American Parent-Child Dyad during Digital Storytelling

    Science.gov (United States)

    Lewis Ellison, Tisha; Wang, Huan

    2018-01-01

    This article examines the digital storytelling practices between an African American mother and son. We used agency as a theoretical framework to explore how the two exercised their own power to collaborate on their digital story. As digital technologies became part of their practice, challenges and tensions arose when both participants attempted…

  2. Genetic control of growth traits and inheritance of resistance to bacterial leaf scorch in American Sycamore

    Science.gov (United States)

    J.P. Adams; R. J. Rousseau; T. D. Leininger

    2012-01-01

    Open-pollinated progeny tests of American sycamore (Platanus occidentalis L.), which included 55 open-pollinated families selected from several prior Westvaco progeny tests and seed orchards and six control-pollinated families were established in 2002 and 2003. The half-sibling families were planted at two sites in western Kentucky and southeastern...

  3. Wonder girls: Undercurrents of resistance in the representation of teenage girls in 1980s American cinema

    NARCIS (Netherlands)

    Wilkinson, M.C.

    2013-01-01

    This thesis explores the representation of teenage girls in 1980s American teen films such as Little Darlings (1980), Smooth Talk (1985), Just One of the Guys (1985), Pretty in Pink (1986) and Mermaids (1990). It uses film analysis and feminist film theory to subject a range of case studies to three

  4. Preliminary investigations of equilibrium reconstruction quality during ELMy and ELM-free phases on JET

    Energy Technology Data Exchange (ETDEWEB)

    Gelfusa, M., E-mail: gelfusa@ing.uniroma2.it [Associazione EURATOM-ENEA—University of Rome “Tor Vergata”, Rome (Italy); Murari, A. [Associazione EURATOM-ENEA per la Fusione, Consorzio RFX, 4-35127 Padova (Italy); Peluso, E. [Associazione EURATOM-ENEA sulla Fusione, ENEA C.R. Frascati, C.P. 65, I-00044 Frascati, Rome (Italy); Gaudio, P. [Associazione EURATOM-ENEA—University of Rome “Tor Vergata”, Rome (Italy); Orsitto, F.P. [Associazione EURATOM-ENEA sulla Fusione, ENEA C.R. Frascati, C.P. 65, I-00044 Frascati, Rome (Italy); Gerasimov, S. [EURATOM/CCFE Fusion Association, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); Collaboration: JET-EFDA Contributors

    2013-08-21

    On JET, the magnetic topology is normally derived from the code EFIT, which solves the Grad–Shafranov equation with constraints imposed by the available measurements, typically the pick-up coils. Both the code and the measurements are expected to perform worse during ELMs. To assess this hypothesis, various statistical indicators, based on the values of the residuals and their probability distribution, have been calculated. They all show that the quality of EFIT reconstructions is clearly better in absence of ELMs. How the responsibility, for the lower quality of the reconstructions, is shared between the measurements and EFIT is a subject under investigation. © 2001 Elsevier Science. All rights reserved.

  5. Localization and quantitative determination of catechins and proanthocyanidins in the phloem of elm and cherry.

    Science.gov (United States)

    Feucht, W; Treutter, D; Christ, E

    1992-03-01

    The localization of catechins and proanthocyanidins in the phloem of elm (Ulmus minor Mill.) and cherry (Prunus avium L.) was determined histochemically by use of 4-dimethylaminocinnamaldehyde (DMACA) reagent. The two tree species showed a characteristic distribution of these phenols, which were most abundant in the phloem rays of cherry, but were largely confined to upright parenchyma cells of elm. Quantitative determination and qualitative separation of catechins and proanthocyanidins were performed using HPLC-CRD (chemical reaction detection), with 4-dimethylaminocinnamaldehyde as the staining reagent. Up to 14 different catechins and proanthocyanidins were found in both species.

  6. High-fat diet is associated with obesity-mediated insulin resistance and β-cell dysfunction in Mexican Americans.

    Science.gov (United States)

    Black, Mary Helen; Watanabe, Richard M; Trigo, Enrique; Takayanagi, Miwa; Lawrence, Jean M; Buchanan, Thomas A; Xiang, Anny H

    2013-04-01

    Consumption of energy-dense, nutrient-poor foods has contributed to the rising incidence of obesity and may underlie insulin resistance and β-cell dysfunction. Macronutrient intake patterns were examined in relation to anthropometric and metabolic traits in participants of BetaGene, a family-based study of obesity, insulin resistance, and β-cell dysfunction in Mexican Americans. Dietary intake, body composition, insulin sensitivity (SI), and β-cell function [Disposition Index (DI)] were assessed by food-frequency questionnaires, dual-energy X-ray absorptiometry, and intravenous glucose-tolerance tests, respectively. Patterns of macronutrient intake were identified by using a K-means model based on the proportion of total energy intake per day attributable to carbohydrate, fat, and protein and were tested for association with anthropometric and metabolic traits. Among 1150 subjects aged 18-65 y (73% female), tertiles of fat intake were associated with greater adiposity and lower SI, after adjustment for age, sex, and daily energy intake. Moreover, 3 distinct dietary patterns were identified: "high fat" (35% fat, 44% carbohydrate, 21% protein; n = 238), "moderate fat" (28% fat, 54% carbohydrate, 18% protein; n = 520), and "low fat" (20% fat, 65% carbohydrate, 15% protein; n = 392). Compared with the low-fat group, the high-fat group had higher age- and sex-adjusted mean body mass index, body fat percentage, and trunk fat and lower SI and DI. Further adjustment for daily energy intake by matching individuals across dietary pattern groups yielded similar results. None of the observed associations were altered after adjustment for physical activity; however, associations with SI and DI were attenuated after adjustment for adiposity. These findings suggest that high-fat diets may contribute to increased adiposity and concomitant insulin resistance and β-cell dysfunction in Mexican Americans.

  7. EXPANDING URBAN AMERICAN INDIAN YOUTHS’ REPERTOIRE OF DRUG RESISTANCE SKILLS: PILOT RESULTS FROM A CULTURALLY ADAPTED PREVENTION PROGRAM

    Science.gov (United States)

    Kulis, Stephen; Dustman, Patricia A.; Brown, Eddie F.; Martinez, Marcos

    2013-01-01

    This article examines changes in the drug resistance strategies used by urban American Indian (UAI) middle school students during a pilot test of a substance use prevention curriculum designed specifically for UAI youth, Living in 2 Worlds (L2W). L2W teaches four drug resistance strategies (refuse, explain, avoid, leave [R-E-A-L]) in culturally appropriate ways. Data come from 57 UAI students (53% female; mean age = 12.5 years) who participated in L2W during an academic enrichment class for Native youth at two Phoenix schools. Students completed a pre-test questionnaire before the L2W lessons and a post-test 7 months later. Questions assessed the use of R-E-A-L and alternative strategies commonly reported by UAI youth (change the subject, use humor). Tests of mean differences from pre-test to post-test showed significant increases in use of refuse, R-E-A-L repertoire. Use of more passive strategies (avoid, use humor) did not change significantly, except for change the subject, which increased. Changes in the use of strategies did not differ significantly by gender, age, school grades, parental education, or length of urban residence. The L2W curriculum appears effective in teaching culturally relevant communication strategies that expand UAI youths’ repertoire of drug resistance skills. PMID:23529769

  8. Occurrence of heavy metals and antibiotic resistance in bacteria from internal organs of american bullfrog (Rana catesbeiana raised in Malaysia

    Directory of Open Access Journals (Sweden)

    SW Lee

    2009-01-01

    Full Text Available A total of 40 bacteria have been successfully isolated from internal organs of the American bullfrog (Rana catesbeiana raised in Malaysia, namely, eight isolates of Aeromonas spp., 21 of Edwardsiella spp., six of Flavobacterium spp. and five of Vibrio spp. In terms of antibiotic susceptibility testing, each isolate was tested against 21 antibiotics, resulting in 482 (57.3% cases of sensitivity and 61 (7.3% cases of partial sensitivity. Meanwhile, 297 (35.4% bacterial isolates were registered as resistant. The multiple antibiotic resistance (MAR index of each bacterial species indicated that bacteria from raised bullfrogs have been exposed to tested antibiotics with results ranging from 0.27 to 0.39. Additionally, high percentages of heavy metal resistance among these isolates were observed, with values ranging from 85.0 to 100.0%. The current results provided us information on bacterial levels of locally farmed bullfrogs exposed to copper, cadmium, chromium as well as 21 types of antibiotics.

  9. Isolation and characterization of microsatellite markers for red elm (Ulmus rubra Muhl.) and cross-species amplification with Siberian elm (Ulmus pumila L.).

    Science.gov (United States)

    Zalapa, J E; Brunet, J; Guries, R P

    2008-01-01

    Ulmus pumila is an elm species, non-native to the USA that hybridizes with Ulmus rubra. In order to study the genetic structure and hybridization patterns between these two elm species, we developed 15 primer pairs for microsatellite loci in U. rubra and tested their cross-amplification in U. pumila. All 15 primers amplified in both species, 11 of which possessed species-specific alleles. Eight loci were polymorphic in U. pumila and eight in U. rubra, each with two to eight alleles per locus. In addition, five primer pairs previously developed in U. laevis and U. carpinifolia (syn. U. minor) cross-amplified and showed polymorphic loci in U. pumila and/or U. rubra. These markers will facilitate the study of genetic structure and gene flow between U. rubra and exotic, invasive U. pumila. © 2007 Blackwell Publishing Ltd No claim to original US government works.

  10. Advances in the Understanding of ELM Suppression by Resonant Magnetic Perturbations (RMPs) in DIII-D and Implications for ITER

    Energy Technology Data Exchange (ETDEWEB)

    Nazikian, R. [PPPL

    2014-09-01

    Experiments on DIII-D have expanding the operating window for RMP ELM suppression to higher q95 with dominant electron heating and fully non-inductive current drive relevant to advanced modes of ITER operation. Robust ELM suppression has also been obtained with a reduced coil set, mitigating the risk of coil failure in maintaining ELM suppression in ITER. These results significantly expand the operating space and reduce risk for obtaining RMP ELM suppression in ITER. Efforts have also been made to search for 3D cause of ELM suppression. No internal non-axisymmetric structure is detected at the top of the pedestal, indicating that the dominant effect of the RMP is to produce an n=0 transport modification of the profiles. Linear two fluid MHD simulations using M3D-C1 indicate resonant field penetration and significant magnetic stochasticity at the top of the pedestal, consistent with the absence of detectable 3D structure in that region. A profile database was developed to compare the scaling of the pedestal and global confinement with the applied 3D field strength in ELM suppressed and ELM mitigated plasmas. The EPED pedestal model accurately predicts the measured pedestal pressure at the threshold of ELM suppression, increasing confidence in theoretical projections to ITER pedestal conditions. Both the H-factor (H(sub)98y2) and thermal energy confinement time do not degrade substantially with applied RMP fields near the threshold of ELM suppression, enhancing confidence in the compatibility of ITER high performance operation with RMP ELM suppression.

  11. Value of American Thoracic Society guidelines in predicting infection or colonization with multidrug-resistant organisms in critically ill patients.

    Directory of Open Access Journals (Sweden)

    Jianfeng Xie

    Full Text Available The incidence rate of infection by multidrug-resistant organisms (MDROs can affect the accuracy of etiological diagnosis when using American Thoracic Society (ATS guidelines. We determined the accuracy of the ATS guidelines in predicting infection or colonization by MDROs over 18 months at a single ICU in eastern China.This prospective observational study examined consecutive patients who were admitted to an intensive care unit (ICU in Nanjing, China. MDROs were defined as bacteria that were resistant to at least three antimicrobial classes, such as methicillin-resistant Staphylococcus aureus (MRSA, vancomycin-resistant enterococci (VRE, Pseudomonas aeruginosa, Acinetobacter baumannii. Screening for MDROs was performed at ICU admission and discharge. Risk factors for infection or colonization with MDROs were recorded, and the accuracy of the ATS guidelines in predicting infection or colonization with MDROs was documented.There were 610 patients, 225 (37% of whom were colonized or infected with MDROs at ICU admission, and this increased to 311 (51% at discharge. At admission, the sensitivity (70.0%, specificity (31.6%, positive predictive value (38.2%, and negative predictive value (63.5%, all based on ATS guidelines for infection or colonization with MDROs were low. The negative predictive value was greater in patients from departments with MDRO infection rates of 31-40% than in patients from departments with MDRO infection rates of 30% or less and from departments with MDRO infection rates more than 40%.ATS criteria were not reliable in predicting infection or colonization with MDROs in our ICU. The negative predictive value was greater in patients from departments with intermediate rates of MDRO infection than in patients from departments with low or high rates of MDRO infection.ClinicalTrials.gov NCT01667991.

  12. Plasma shaping and its impact on the pedestal of ASDEX Upgrade: edge stability and inter-ELM dynamics at varied triangularity

    Science.gov (United States)

    Laggner, F. M.; Wolfrum, E.; Cavedon, M.; Dunne, M. G.; Birkenmeier, G.; Fischer, R.; Willensdorfer, M.; Aumayr, F.; The EUROfusion MST1 Team; The ASDEX Upgrade Team

    2018-04-01

    The plasma shape, in particular the triangularity (δ), impacts on the pedestal stability. A scan of δ including a variation of heating power (P heat) and gas puff was performed to study the behaviour of edge localised modes (ELMs) and the pre-ELM pedestal stability for different plasma shapes. Generally, at higher δ the pedestal top electron density (n e) is enhanced and the ELM repetition frequency (f ELM) is reduced. For all δ, the pedestal top n e is already fully established to its pre-ELM value during the initial recovery phase of the n e pedestal, which takes place immediately after the ELM crash. The lowering of the f ELM with increasing δ is related to longer pedestal recovery phases, especially the last pre-ELM phase with clamped pedestal gradients (after the recovery phases of the n e and electron temperature (T e) pedestal) is extended. In all investigated discharge intervals, the pre-ELM pedestal profiles are in agreement with peeling-ballooning (PB) theory. Over the investigated range of δ, two well-separated f ELM bands are observed in several discharge intervals. Their occurrence is linked to the inter-ELM pedestal stability. In both kinds of ELM cycles the pedestal evolves similarly, however, the ‘fast’ ELM cycle occurs before the global plasma stored energy (W MHD) increases, which then provides a stabilising effect on the pedestal, extending the inter-ELM period in the case of the ‘slow’ ELM cycle. At the end of a ‘fast’ ELM cycle the n e profile is radially shifted inwards relative to the n e profile at the end of a ‘slow’ ELM cycle, leading to a reduced pressure gradient. The appearance of two f ELM bands suggests that the pedestal becomes more likely PB unstable in certain phases of the inter-ELM evolution. Such a behaviour is possible because the evolution of the global plasma is not rigidly coupled to the evolution of the pedestal structure on the timescales of an ELM cycle.

  13. Use Correlation Coefficients in Gaussian Process to Train Stable ELM Models

    Science.gov (United States)

    2015-05-22

    correlation coefficients to avoid the covariance matrix to become a singular matrix and make the inverse of covariance matrix solvable. We have used 12 UCI and...Curves for training and testing accuracies of different ELMs changing with L on Treasury Dataset 4 Experiments In this section, we use 12 UCI and KEEL

  14. Multigrades Classification Model of Magnesite Ore Based on SAE and ELM

    Directory of Open Access Journals (Sweden)

    Yachun Mao

    2017-01-01

    Full Text Available Magnesite is an important raw material for extracting magnesium metal and magnesium compound; how precise its grade classification exerts great influence on the smelting process. Thus, it is increasingly important to determine fast and accurately the grade of magnesite. In this paper, a method based on stacked autoencoder (SAE and extreme learning machine (ELM was established for the classification model of magnesite. Stacked autoencoder (SAE was firstly used to reduce the dimension of magnesite spectrum data and then neutral network model of extreme learning machine (ELM was adopted to classify the data. Two improved extreme learning machine (ELM models were employed for better classification, namely, accuracy extreme learning machine (AELM and integrated accuracy (IELM to build up the classification models. The grade classification through traditional methods such as chemical approaches, artificial methods, and BP neutral network model was compared to that in this paper. Results showed that the classification model of magnesite ore through stacked autoencoder (SAE and extreme learning machine (ELM is better in terms of speed and accuracy; thus, this paper provides a new way for the grade classification of magnesite ore.

  15. High Frequency ELM Pacing by Lithium Pellet Injection on DIII-D

    Science.gov (United States)

    Bortolon, A.; Maingi, R.; Mansfield, D. K.; Nagy, A.; Roquemore, A. L.; Lunsford, R.; Jackson, G. L.; Osborne, T. H.; Parks, P. B.

    2015-11-01

    Full-shot, high-frequency pacing of edge localized modes (ELM) by lithium pellet injection has been demonstrated in DIII-D. A Lithium Granule Injector (LGI), recently installed on DIII-D to study pacing efficiency dependence on granule size and velocity, was tested in different ELMy scenarios (βN = 1.2-2.0) injecting granules of nominal diameter 0.3-0.9 mm, with injection speed 50-120 m/s and injection rates up to 500 Hz. Robust ELM pacing was documented on time windows up to 3.5 s, with triggering efficiency close to 100% obtained with 0.9 mm diameter granules, lower with smaller sizes and weakly dependent on granule velocity. Paced ELM frequencies up to 100 Hz were achieved, with a 2-5 fold increase over the natural ELM frequency and a consequent reduction of divertor peak heat flux. Overall, LGI high frequency pacing appeared to be compatible with high plasma performance, in terms of global confinement and pedestal characteristics. Work supported by the US Department of Energy under DE-AC02-09CH11466, DE-FC02-04ER54698.

  16. Clitocybe tabescens associated with decline and death of Chinese elm and water oak

    Science.gov (United States)

    T. H. Filer; F. I. McCracken

    1969-01-01

    In 1964, decline symptoms were found on 48 Chinese elms (Ulmus parvifolia) and 2 water oaks (Quercus nigra) in Washington County, Mississippi. Some of their foliage was yellowish, and small lateral branches were dying in parts of the crowns. Large branches later died and the entire crowns were infected.

  17. Investigation of ELM [edge localized mode] Dynamics with the Resonant Magnetic Perturbation Effects

    Energy Technology Data Exchange (ETDEWEB)

    Pankin, Alexei Y.; Kritz, Arnold H.

    2011-07-19

    Topics covered are: anomalous transport and E x B flow shear effects in the H-mode pedestal; RMP (resonant magnetic perturbation) effects in NSTX discharges; development of a scaling of H-mode pedestal in tokamak plasmas with type I ELMs (edge localized modes); and divertor heat load studies.

  18. Investigation of transient melting of tungsten by ELMs in ASDEX Upgrade

    Science.gov (United States)

    Krieger, K.; Sieglin, B.; Balden, M.; Coenen, J. W.; Göths, B.; Laggner, F.; de Marne, P.; Matthews, G. F.; Nille, D.; Rohde, V.; Dejarnac, R.; Faitsch, M.; Giannone, L.; Herrmann, A.; Horacek, J.; Komm, M.; Pitts, R. A.; Ratynskaia, S.; Thoren, E.; Tolias, P.; ASDEX-Upgrade Team; EUROfusion MST1 Team

    2017-12-01

    Repetitive melting of tungsten by power transients originating from edge localized modes (ELMs) has been studied in the tokamak experiment ASDEX Upgrade. Tungsten samples were exposed to H-mode discharges at the outer divertor target plate using the Divertor Manipulator II system. The exposed sample was designed with an elevated sloped surface inclined against the incident magnetic field to increase the projected parallel power flux to a level were transient melting by ELMs would occur. Sample exposure was controlled by moving the outer strike point to the sample location. As extension to previous melt studies in the new experiment both the current flow from the sample to vessel potential and the local surface temperature were measured with sufficient time resolution to resolve individual ELMs. The experiment provided for the first time a direct link of current flow and surface temperature during transient ELM events. This allows to further constrain the MEMOS melt motion code predictions and to improve the validation of its underlying model assumptions. Post exposure ex situ analysis of the retrieved samples confirms the decreased melt motion observed at shallower magnetic field line to surface angles compared to that at leading edges exposed to the parallel power flux.

  19. Using ELM-based weighted probabilistic model in the classification of synchronous EEG BCI.

    Science.gov (United States)

    Tan, Ping; Tan, Guan-Zheng; Cai, Zi-Xing; Sa, Wei-Ping; Zou, Yi-Qun

    2017-01-01

    Extreme learning machine (ELM) is an effective machine learning technique with simple theory and fast implementation, which has gained increasing interest from various research fields recently. A new method that combines ELM with probabilistic model method is proposed in this paper to classify the electroencephalography (EEG) signals in synchronous brain-computer interface (BCI) system. In the proposed method, the softmax function is used to convert the ELM output to classification probability. The Chernoff error bound, deduced from the Bayesian probabilistic model in the training process, is adopted as the weight to take the discriminant process. Since the proposed method makes use of the knowledge from all preceding training datasets, its discriminating performance improves accumulatively. In the test experiments based on the datasets from BCI competitions, the proposed method is compared with other classification methods, including the linear discriminant analysis, support vector machine, ELM and weighted probabilistic model methods. For comparison, the mutual information, classification accuracy and information transfer rate are considered as the evaluation indicators for these classifiers. The results demonstrate that our method shows competitive performance against other methods.

  20. Modelling ELM heat flux deposition on the ITER main chamber wall

    Czech Academy of Sciences Publication Activity Database

    Kočan, M.; Pitts, R.A.; Lisgo, S.W.; Loarte, A.; Gunn, J. P.; Fuchs, Vladimír

    2015-01-01

    Roč. 463, July (2015), s. 709-713 ISSN 0022-3115. [International Conference on Plasma-Surface Interactions in Controlled Fusion Devices (PSI)/21./. Kanazawa, 26.05.2014-30.05.2014] Institutional support: RVO:61389021 Keywords : ELM * ITER Subject RIV: JF - Nuclear Energetics OBOR OECD: Nuclear related engineering Impact factor: 2.199, year: 2015

  1. Some Guides to Discovery About Elm Trees, Owls, Cockroaches, Earthworms, Cement and Concrete.

    Science.gov (United States)

    Busch, Phyllis S.

    The introduction emphasizes the need for environmental and conservation education, and advocates an inquiry approach. Outdoor resources available to every school are listed. Detailed suggestions are made for investigating cement and concrete, cockroaches, earthworms, elm trees, and owls. In each case general background information and a list of…

  2. An elm EST database for identifying leaf beetle egg-induced defense genes

    Directory of Open Access Journals (Sweden)

    Büchel Kerstin

    2012-06-01

    Full Text Available Abstract Background Plants can defend themselves against herbivorous insects prior to the onset of larval feeding by responding to the eggs laid on their leaves. In the European field elm (Ulmus minor, egg laying by the elm leaf beetle ( Xanthogaleruca luteola activates the emission of volatiles that attract specialised egg parasitoids, which in turn kill the eggs. Little is known about the transcriptional changes that insect eggs trigger in plants and how such indirect defense mechanisms are orchestrated in the context of other biological processes. Results Here we present the first large scale study of egg-induced changes in the transcriptional profile of a tree. Five cDNA libraries were generated from leaves of (i untreated control elms, and elms treated with (ii egg laying and feeding by elm leaf beetles, (iii feeding, (iv artificial transfer of egg clutches, and (v methyl jasmonate. A total of 361,196 ESTs expressed sequence tags (ESTs were identified which clustered into 52,823 unique transcripts (Unitrans and were stored in a database with a public web interface. Among the analyzed Unitrans, 73% could be annotated by homology to known genes in the UniProt (Plant database, particularly to those from Vitis, Ricinus, Populus and Arabidopsis. Comparative in silico analysis among the different treatments revealed differences in Gene Ontology term abundances. Defense- and stress-related gene transcripts were present in high abundance in leaves after herbivore egg laying, but transcripts involved in photosynthesis showed decreased abundance. Many pathogen-related genes and genes involved in phytohormone signaling were expressed, indicative of jasmonic acid biosynthesis and activation of jasmonic acid responsive genes. Cross-comparisons between different libraries based on expression profiles allowed the identification of genes with a potential relevance in egg-induced defenses, as well as other biological processes, including signal transduction

  3. An elm EST database for identifying leaf beetle egg-induced defense genes.

    Science.gov (United States)

    Büchel, Kerstin; McDowell, Eric; Nelson, Will; Descour, Anne; Gershenzon, Jonathan; Hilker, Monika; Soderlund, Carol; Gang, David R; Fenning, Trevor; Meiners, Torsten

    2012-06-15

    Plants can defend themselves against herbivorous insects prior to the onset of larval feeding by responding to the eggs laid on their leaves. In the European field elm (Ulmus minor), egg laying by the elm leaf beetle ( Xanthogaleruca luteola) activates the emission of volatiles that attract specialised egg parasitoids, which in turn kill the eggs. Little is known about the transcriptional changes that insect eggs trigger in plants and how such indirect defense mechanisms are orchestrated in the context of other biological processes. Here we present the first large scale study of egg-induced changes in the transcriptional profile of a tree. Five cDNA libraries were generated from leaves of (i) untreated control elms, and elms treated with (ii) egg laying and feeding by elm leaf beetles, (iii) feeding, (iv) artificial transfer of egg clutches, and (v) methyl jasmonate. A total of 361,196 ESTs expressed sequence tags (ESTs) were identified which clustered into 52,823 unique transcripts (Unitrans) and were stored in a database with a public web interface. Among the analyzed Unitrans, 73% could be annotated by homology to known genes in the UniProt (Plant) database, particularly to those from Vitis, Ricinus, Populus and Arabidopsis. Comparative in silico analysis among the different treatments revealed differences in Gene Ontology term abundances. Defense- and stress-related gene transcripts were present in high abundance in leaves after herbivore egg laying, but transcripts involved in photosynthesis showed decreased abundance. Many pathogen-related genes and genes involved in phytohormone signaling were expressed, indicative of jasmonic acid biosynthesis and activation of jasmonic acid responsive genes. Cross-comparisons between different libraries based on expression profiles allowed the identification of genes with a potential relevance in egg-induced defenses, as well as other biological processes, including signal transduction, transport and primary metabolism

  4. Characterizations of power loads on divertor targets for type-I, compound and small ELMs in the EAST superconducting tokamak

    DEFF Research Database (Denmark)

    Wang, L.; Xu, G.S.; Guo, H.Y.

    2013-01-01

    -III ELMy H-modes. The energy loss and divertor power load are systematically characterized for these different ELMy H-modes to provide a physics basis for the next-step high-power long-pulse operations in EAST. Both type-I and compound ELMs exhibit good confinement (H98(y,2) ∼ 1). A significant loss......The Experimental Advanced Superconducting Tokamak (EAST) has recently achieved a variety of H-mode regimes with different edge-localized mode (ELM) dynamics, including type-I ELMs, compound ELMs, which are manifested by the onset of a large spike followed by a sequence of small spikes on Dα......-III ELMs. It is remarkable that the new very small ELMy H-modes exhibit even lower target power deposition than type-III ELMs, with the peak heat flux generally below 1 MW m−2. These very small ELMs are usually accompanied by broadband fluctuations with frequencies ranging from 20 to 50 kHz, which may...

  5. High-Fat Diet Is Associated with Obesity-Mediated Insulin Resistance and β-Cell Dysfunction in Mexican Americans123

    OpenAIRE

    Black, Mary Helen; Watanabe, Richard M.; Trigo, Enrique; Takayanagi, Miwa; Lawrence, Jean M.; Buchanan, Thomas A.; Xiang, Anny H.

    2013-01-01

    Consumption of energy-dense, nutrient-poor foods has contributed to the rising incidence of obesity and may underlie insulin resistance and β-cell dysfunction. Macronutrient intake patterns were examined in relation to anthropometric and metabolic traits in participants of BetaGene, a family-based study of obesity, insulin resistance, and β-cell dysfunction in Mexican Americans. Dietary intake, body composition, insulin sensitivity (SI), and β-cell function [Disposition Index (DI)] were asses...

  6. Engineered resistance in Aedes aegypti to a West African and a South American strain of yellow fever virus.

    Science.gov (United States)

    Higgs, S; Rayner, J O; Olson, K E; Davis, B S; Beaty, B J; Blair, C D

    1998-05-01

    Double subgenomic Sindbis (dsSIN) viruses were engineered to transduce mosquito cells with antisense RNA derived either from the premembrane (prM) or polymerase (NS5) coding regions of the 17D vaccine strain of yellow fever virus (YFV). Aedes albopictus C6/36 cells were infected at high multiplicities of infection (MOI) with each dsSIN virus. Forty-eight hours later, the transduced cells were challenged with an MOI of 0.1 of the Asibi strain of YFV. At 72-hr postchallenge, the cells were assayed by immunofluorescence for the presence of YFV antigen. Cells transduced with prM or NS5 antisense RNAs derived from the YFV genome displayed no YFV-specific antigens. In contrast, cells infected with control dsSIN viruses that expressed no antisense RNA or dengue virus-derived antisense RNAs were permissive for the challenge virus. To analyze resistance in the mosquito, five log10 50% tissue culture infective doses (TCID50) of each dsSIN virus and three log10TCID50 of either a West African (BA-55) or South American (1899/81) strain of wild-type YFV were coinoculated into Ae. aegypti. Mosquitoes transduced with effector RNAs targeting the prM or NS5 gene regions did not transmit West African YFV and poorly transmitted the South American strain of YFV.

  7. Effects of elm bark (Ulmus davidiana var. japonica) extracts on the modulation of immunocompetence in mice.

    Science.gov (United States)

    Lee, Yousuk; Park, Hyunjin; Ryu, Hye Sook; Chun, Mison; Kang, Seunghee; Kim, Hyun-Sook

    2007-03-01

    The immunomodulative effects of elm bark extract were studied in vitro by the proliferation of splenocytes and the production capacity of three kinds of cytokines [interleukin (IL)-1beta, IL-6, and tumor necrosis factor (TNF)-alpha] by mouse peritoneal macrophages cultured with various fractions (methanol, hexane, chloroform, ethyl acetate, butanol, and water) of elm bark extract. Splenocyte proliferation and cell viability of peritoneal macrophages were increased with concentrations of polar fractions, such as butanol and water, in the range of 1-500 microg/mL. Significantly higher levels of the production of all three cytokines were detected with supplementation of methanol extract compared with other fractions. In order to elucidate its effect in vivo, elm bark water extract was orally administrated every other day for 2 weeks. Proliferation of splenocytes and the production capacity of cytokines (IL-1beta, IL-6, and TNF-alpha) by mouse peritoneal macrophages were used as indices for immune activity. Splenocyte proliferation induced by elm bark with lipopolysaccharide or concanavalin A stimulation was enhanced at 500 mg/kg of body weight concentrations compared to that of the control group. In the case of cytokines, the highest production of IL-6 and TNF was detected at 500 mg/kg of body weight concentrations. In conclusion, this study suggests through in vitro and in vivo experiments that Ulmus davidiana var. japonica (elm bark) extracts may enhance the immunocompetent properties such as splenocyte proliferation and cytokine production capacity by activated macrophages and have a protective effect in mice.

  8. Modeling of mechanisms responsible for ELM mitigation by external magnetic field perturbations

    International Nuclear Information System (INIS)

    Tokar, M.Z.; Rogister, A.L.; Wolf, R.C.; Singh, R.; Kaw, P.

    2007-01-01

    Edge-Localized Modes (ELMs) is an intrinsic feature of the high confinement H-mode in tokamaks. On the one hand, they are beneficial for stationary discharge performance by expelling from the plasma impurities produced at the machine walls. On the other hand, under reactor conditions type I ELMs would themselves lead to a dramatic increase of impurity release and cause very large pulse heat loads on divertor plates. Therefore, it is crucial to find a way to mitigate ELMs without negative consequences for the plasma. Recent experiments on the tokamak D-III D have demonstrated that by applying resonant magnetic field perturbations from external coils, large type I ELMs can be effectively mitigated without any significant loss of confinement quality. This mode of operation is highly desirable for future fusion reactors and therefore it is very important to achieve an understanding of physical mechanism leading to ELMs suppression through external field perturbations. In the present contribution ballooning-pealing MHD instability considered normally as the main cause of the edge localized modes of type I, is theoretically examined in the presence of external magnetic field perturbations by applying a mode-mode coupling technique. It is demonstrated that through non-linear interaction, leading to the generation of side bands which suck energy from the main mode, such perturbations can raise the threshold of MHD instabilities. The synergy of this effect with the influence of external perturbations on the particle and energy transport in the edge transport barrier is studied by applying a simple model for the time variation of plasma parameters in the edge transport barrier. It is demonstrated that this synergy can be very beneficial for the plasma performance. In future experiments on JET and ITER it may lead to a noticeable increase of the pedestal pressure compared to the standard H-mode operation. (author)

  9. Spatial Distribution and Site-Specific Spraying of Main Sucking Pests of Elm Trees.

    Science.gov (United States)

    Karimzadeh, R; Iranipour, S

    2017-06-01

    Elm trees are important landscape trees and sucking insects weaken the elm trees and produce large amounts of honeydew. The main objectives of this study were to identify main honeydew-producing pests of elm trees and do site-specific spraying against these pests. To map the spatial distribution of the sucking pests in the large scale, the study area was divided into 40 × 40 m grids and one tree was chosen randomly from each grid (a total of 55 trees). These trees were sampled twice a year in 2011 and 2012. Each sample was a 30-cm branch terminal. Eight samples were taken from each tree in four cardinal directions and two canopy levels. The number of sucking insects and leaves of each sample were counted and recorded. Spatial analysis of the data was carried out using geostatistics. Kriging was used for producing prediction maps. Insecticide application was restricted to the regions with populations higher than threshold. To identify within-tree distribution of the honeydew-producing pests, six and four elm trees were chosen in 2011 and 2012 respectively, and sampled weekly. These trees were sampled as described previously. European elm scale (EES), Gossyparia spuria (Modeer) and two species of aphids were the dominant honeydew-producing pests. The results revealed that the effects of direction, canopy level and their interactions on insect populations were not statistically significant (P < 0.05). Site-specific spraying decreased the amount of insecticides used by ca. 20%, while satisfactory control of the sucking pests and honeydew excretion was obtained. Considering the environmental and economic benefits of site-specific spraying, it is worth doing more complementary works in this area.

  10. The resistance of a North American bat species (Eptesicus fuscus to White-nose Syndrome (WNS.

    Directory of Open Access Journals (Sweden)

    Craig L Frank

    Full Text Available White-nose Syndrome (WNS is the primary cause of over-winter mortality for little brown (Myotis lucifugus, northern (Myotis septentrionalis, and tricolored (Perimyotis subflavus bats, and is due to cutaneous infection with the fungus Pseudogymnoascus (Geomyces destructans (Pd. Cutaneous infection with P. destructans disrupts torpor patterns, which is thought to lead to a premature depletion of body fat reserve. Field studies were conducted at 3 WNS-affected hibernation sites to determine if big brown bats (Eptesicus fuscus are resistant to Pd. Radio telemetry studies were conducted during 2 winters to determine the torpor patterns of 23 free-ranging E. fuscus hibernating at a site where Pd occurs. The body fat contents of free-ranging E. fuscus and M. lucifugus during hibernation at 2 different WNS-affected sites were also determined. The numbers of bats hibernating at the same site was determined during both: a 4-7 years prior to the arrival of Pd, and, b 2-3 years after it first appeared at this site. The torpor bouts of big brown bats hibernating at a WNS-affected site were not significantly different in length from those previously reported for this species. The mean body fat content of E. fuscus in February was nearly twice that of M. lucifugus hibernating at the same WNS-affected sites during this month. The number of M. lucifugus hibernating at one site decreased by 99.6% after P. destructans first appeared, whereas the number of E. fuscus hibernating there actually increased by 43% during the same period. None of the E. fuscus collected during this study had any visible fungal growth or lesions on their skin, whereas virtually all the M. lucifugus collected had visible fungal growth on their wings, muzzle, and ears. These findings indicate that big brown bats are resistant to WNS.

  11. Molecular Epidemiology of Vancomycin-Resistant Enterococcus faecium: a Prospective, Multicenter Study in South American Hospitals▿

    Science.gov (United States)

    Panesso, Diana; Reyes, Jinnethe; Rincón, Sandra; Díaz, Lorena; Galloway-Peña, Jessica; Zurita, Jeannete; Carrillo, Carlos; Merentes, Altagracia; Guzmán, Manuel; Adachi, Javier A.; Murray, Barbara E.; Arias, Cesar A.

    2010-01-01

    Enterococcus faecium has emerged as an important nosocomial pathogen worldwide, and this trend has been associated with the dissemination of a genetic lineage designated clonal cluster 17 (CC17). Enterococcal isolates were collected prospectively (2006 to 2008) from 32 hospitals in Colombia, Ecuador, Perú, and Venezuela and subjected to antimicrobial susceptibility testing. Genotyping was performed with all vancomycin-resistant E. faecium (VREfm) isolates by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing. All VREfm isolates were evaluated for the presence of 16 putative virulence genes (14 fms genes, the esp gene of E. faecium [espEfm], and the hyl gene of E. faecium [hylEfm]) and plasmids carrying the fms20-fms21 (pilA), hylEfm, and vanA genes. Of 723 enterococcal isolates recovered, E. faecalis was the most common (78%). Vancomycin resistance was detected in 6% of the isolates (74% of which were E. faecium). Eleven distinct PFGE types were found among the VREfm isolates, with most belonging to sequence types 412 and 18. The ebpAEfm-ebpBEfm-ebpCEfm (pilB) and fms11-fms19-fms16 clusters were detected in all VREfm isolates from the region, whereas espEfm and hylEfm were detected in 69% and 23% of the isolates, respectively. The fms20-fms21 (pilA) cluster, which encodes a putative pilus-like protein, was found on plasmids from almost all VREfm isolates and was sometimes found to coexist with hylEfm and the vanA gene cluster. The population genetics of VREfm in South America appear to resemble those of such strains in the United States in the early years of the CC17 epidemic. The overwhelming presence of plasmids encoding putative virulence factors and vanA genes suggests that E. faecium from the CC17 genogroup may disseminate in the region in the coming years. PMID:20220167

  12. Melatonin enhances the recovery of cryopreserved shoot tips of American elm (Ulmus Americana L.)

    Science.gov (United States)

    Climate change and the global migrations of people and goods have exposed trees to new diseases and abiotic challenges that threaten the survival of species. In vitro germplasm storage via cryopreservation is an effective tool to ensure conservation of tree species, but plant cells and tissues are e...

  13. American Ginseng

    Science.gov (United States)

    ... and inflammation of the lining of the stomach (gastritis). American ginseng is also used for low iron in the blood (anemia), diabetes, insulin resistance related to HIV treatments, cancer-related fatigue, high blood pressure, trouble sleeping (insomnia), ...

  14. Observation of Abrupt- and Fast-rising SOL Current during Trigger Phase of ELMs in DIII-D Tokamak

    Energy Technology Data Exchange (ETDEWEB)

    H. Takahashi; E.D. Fredrickson; M.J. Schaffer; M.E. Austin; N.H. Brooks; T.E. Evans; G.L. Jackson; L.L. Lao; J.G. Watkins

    2005-06-27

    Extensive studies to date of edge localized modes (ELMs) have sought their origin inside the separatrix, i.e., MHD instability from steep gradients in the plasma edge, and examined their consequences outside the separatrix, i.e., transport of heat and particles in the scrape-off-layer (SOL) and divertors. Recent measurement by a high-speed scrape-off-layer current (SOLC) diagnostic may indicate that the ELM trigger process lies, in part, in the SOL. Thermoelectrically driven SOLC precedes, or co-evolves with, other parameters of the ELM process, and thus can potentially play a causal role: error field generated by non-axisymmetric SOLC, flowing in the immediate vicinity (approximately 1 cm) of the plasma edge, may contribute toward destabilizing MHD modes. The SOLC, observed concurrently with MHD activity, including ELMs, has been reported elsewhere.

  15. Variation in PPARG is associated with longitudinal change in insulin resistance in Mexican Americans at risk for type 2 diabetes.

    Science.gov (United States)

    Black, Mary Helen; Wu, Jun; Takayanagi, Miwa; Wang, Nan; Taylor, Kent D; Haritunians, Talin; Trigo, Enrique; Lawrence, Jean M; Watanabe, Richard M; Buchanan, Thomas A; Xiang, Anny H

    2015-03-01

    Peroxisome proliferator-activated receptor gamma (PPARG) is a susceptibility locus for type 2 diabetes mellitus (T2DM). Although cross-sectional associations have been reported, primarily for Pro12Ala, few longitudinal studies in nondiabetic populations have been conducted. This study aimed to examine whether and to what extent variation in PPARG is associated with longitudinal changes in anthropometric and metabolic traits in Mexican Americans at risk for T2DM. Subjects were participants of BetaGene, a family-based study of obesity, insulin resistance, and β-cell function, who completed a baseline and follow-up study visit (n = 378; mean followup, 4.6 ± 1.5 y). Phenotypes included body fat assessed by dual-energy x-ray absorptiometry; insulin sensitivity (SI), acute insulin response, and β-cell function (disposition index; DI) were estimated from iv glucose tolerance tests with Minimal Model analysis. Eighteen tag single nucleotide polymorphisms (SNPs) capturing variation in a 156-kb region surrounding PPARG were tested for association with changes in longitudinal traits. P-values were Bonferroni-corrected for multiple testing. Six SNPs (rs2972164, rs11128598, rs17793951, rs1151996, rs1175541, rs3856806) were significantly associated with rate of change in SI after adjustment for age, sex, and body fat percentage, but not with changes in adiposity. rs17793951 also had a significant effect on change in DI over time. Association between rs1175541 and change in SI varied by changes in adiposity such that only carriers of the minor allele who reduced body fat over followup improved SI. rs1306470 (captured Pro12Ala, r(2) = 0.9) was not associated with rates of change in any traits and its effects were not modified by changes in adiposity. Variation in PPARG, but not Pro12Ala, contributes to declining SI and concomitant deterioration in β-cell function in Mexican Americans at risk for T2DM.

  16. Progress on the application of ELM control schemes to ITER scenarios from the non-active phase to DT operation

    Czech Academy of Sciences Publication Activity Database

    Loarte, A.; Huijsmans, G.; Futatani, S.; Baylor, L.R.; Evans, T.E.; Orlov, D.M.; Schmitz, O.; Bécoulet, M.; Cahyna, Pavel; Gribov, Y.; Kavin, A.; Sashala Naik, A.; Campbell, D.J.; Casper, T.; Daly, E.; Frerichs, H.; Kischner, A.; Laengner, R.; Lisgo, S.; Pitts, R.A.; Saibene, G.; Wingen, A.

    2014-01-01

    Roč. 54, č. 3 (2014), 033007-033007 ISSN 0029-5515 Institutional support: RVO:61389021 Keywords : ELM (edge localized mode) * ITER * ELM control * pellet pacing * RMP (resonant magnetic perturbation) Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 3.062, year: 2014 http://iopscience.iop.org/0029-5515/54/3/033007/pdf/0029-5515_54_3_033007.pdf

  17. A new intelligent classifier for breast cancer diagnosis based on a rough set and extreme learning machine: RS + ELM

    OpenAIRE

    KAYA, Yılmaz

    2014-01-01

    Breast cancer is one of the leading causes of death among women all around the world. Therefore, true and early diagnosis of breast cancer is an important problem. The rough set (RS) and extreme learning machine (ELM) methods were used collectively in this study for the diagnosis of breast cancer. The unnecessary attributes were discarded from the dataset by means of the RS approach. The classification process by means of ELM was performed using the remaining attributes. The Wisconsin B...

  18. ELM - A SIMPLE TOOL FOR THERMAL-HYDRAULIC ANALYSIS OF SOLID-CORE NUCLEAR ROCKET FUEL ELEMENTS

    Science.gov (United States)

    Walton, J. T.

    1994-01-01

    ELM is a simple computational tool for modeling the steady-state thermal-hydraulics of propellant flow through fuel element coolant channels in nuclear thermal rockets. Written for the nuclear propulsion project of the Space Exploration Initiative, ELM evaluates the various heat transfer coefficient and friction factor correlations available for turbulent pipe flow with heat addition. In the past, these correlations were found in different reactor analysis codes, but now comparisons are possible within one program. The logic of ELM is based on the one-dimensional conservation of energy in combination with Newton's Law of Cooling to determine the bulk flow temperature and the wall temperature across a control volume. Since the control volume is an incremental length of tube, the corresponding pressure drop is determined by application of the Law of Conservation of Momentum. The size, speed, and accuracy of ELM make it a simple tool for use in fuel element parametric studies. ELM is a machine independent program written in FORTRAN 77. It has been successfully compiled on an IBM PC compatible running MS-DOS using Lahey FORTRAN 77, a DEC VAX series computer running VMS, and a Sun4 series computer running SunOS UNIX. ELM requires 565K of RAM under SunOS 4.1, 360K of RAM under VMS 5.4, and 406K of RAM under MS-DOS. Because this program is machine independent, no executable is provided on the distribution media. The standard distribution medium for ELM is one 5.25 inch 360K MS-DOS format diskette. ELM was developed in 1991. DEC, VAX, and VMS are trademarks of Digital Equipment Corporation. Sun4 and SunOS are trademarks of Sun Microsystems, Inc. IBM PC is a registered trademark of International Business Machines. MS-DOS is a registered trademark of Microsoft Corporation.

  19. No Effect of Added Sugar Consumed at Median American Intake Level on Glucose Tolerance or Insulin Resistance

    Directory of Open Access Journals (Sweden)

    Joshua Lowndes

    2015-10-01

    Full Text Available Excess sugar consumption may promote adverse changes in hepatic and total body insulin resistance. Debate continues over the effects of sugars at more typically consumed levels and whether the identity of the sugar consumed is important. In the present study participants (20–60 years old were randomly assigned to one of five groups, three that consumed low fat milk with added fructose containing sugars in amounts equivalent to the 50th percentile of fructose consumption (US, one which consumed low-fat milk sweetened with glucose, and one unsweetened low-fat milk control group. The intervention lasted ten weeks. In the entire study population there was less than 1 kg increase in weight (73.6 ±13.0 vs. 74.5 ± 13.3 kg, p < 0.001, but the change in weight was comparable among groups (p > 0.05. There were no changes in fasting glucose (49 ± 0.4 vs. 5.0 ± 0.5 mmol/L, insulin (56.9 ± 38.9 vs. 61.8 ± 50.0 pmol/L, or insulin resistance, as measured by the Homeostasis Model Assessment method (1.8 ± 1.3 vs. 2.0 ± 1.5, all p > 0.05. These data suggest that added sugar consumed at the median American intake level does not produce changes in measures of insulin sensitivity or glucose tolerance and that no sugar has more deleterious effects than others.

  20. Investigations on the edge kinetic data in regimes with type-I and mitigated ELMs at ASDEX Upgrade

    International Nuclear Information System (INIS)

    Rathgeber, S.K.; Barrera, L.; Birkenmeier, G.; Fischer, R.; Suttrop, W.

    2014-01-01

    The behaviour of profiles and gradients of electron density, temperature and pressure at the edge of ASDEX Upgrade was studied in regimes with type-I and small edge localized modes (ELMs) of discharges with and without applied magnetic perturbations (MPs). Estimation of the edge kinetic parameters was performed by means of integrated data analysis for joint reconstruction of electron density and temperature profiles via combination of data from different diagnostics. The MP fields for ELM mitigation were produced by 16 in-vessel coils allowing to execute this survey with large variations in poloidal spectrum and resonant component of the error field. With several dedicated discharges the effect of MPs on the edge kinetic data and ELMs was determined in dependence of heating power, gas puff and MP-coil configuration. Small ELMs are dominant—with and without MPs—in regimes with reduced pedestal top electron temperatures and flattened edge electron pressure gradients compared to type-I ELM phases. Furthermore, application of MPs opens an additional small ELM regime in the high temperature range at reduced electron pressure gradient. (paper)

  1. An ELM-Based Approach for Estimating Train Dwell Time in Urban Rail Traffic

    Directory of Open Access Journals (Sweden)

    Wen-jun Chu

    2015-01-01

    Full Text Available Dwell time estimation plays an important role in the operation of urban rail system. On this specific problem, a range of models based on either polynomial regression or microsimulation have been proposed. However, the generalization performance of polynomial regression models is limited and the accuracy of existing microsimulation models is unstable. In this paper, a new dwell time estimation model based on extreme learning machine (ELM is proposed. The underlying factors that may affect urban rail dwell time are analyzed first. Then, the relationships among different factors are extracted and modeled by ELM neural networks, on basis of which an overall estimation model is proposed. At last, a set of observed data from Beijing subway is used to illustrate the proposed method and verify its overall performance.

  2. AN ELM FOR BI-CLASSIFICATION OF VERTICALLY BUNDLED ELECTRICITY MARKET PRICES

    Directory of Open Access Journals (Sweden)

    S Anbazhagan

    2018-10-01

    Full Text Available Electricity price forecasting is a challenging problem owing to the very great volatility of price which depends on many factors. This is especially prominent for both producers and consumers where a versatile price forecasting is crucial. This paper contributes an extreme learning machine (ELM to classify the prices. These price classifications are essential since all market players do not know the precise value of future prices in their deciding procedure. In this paper, bi-classification model is proposed for prices utilizing the pre-specified price threshold. Three alternative classification models based on neural networks (NNs are also proposed in bi-classification of prices. The performance of the proposed models is compared in terms of classification error and accuracy. The simulation results show that the ELM classification model is superior compared to three other classification models based on NNs. The performances of our models are evaluated using real data from vertically unbundled mainland Spain power system market.

  3. Fault Diagnosis for Analog Circuits by Using EEMD, Relative Entropy, and ELM.

    Science.gov (United States)

    Xiong, Jian; Tian, Shulin; Yang, Chenglin

    2016-01-01

    This paper presents a novel fault diagnosis method for analog circuits using ensemble empirical mode decomposition (EEMD), relative entropy, and extreme learning machine (ELM). First, nominal and faulty response waveforms of a circuit are measured, respectively, and then are decomposed into intrinsic mode functions (IMFs) with the EEMD method. Second, through comparing the nominal IMFs with the faulty IMFs, kurtosis and relative entropy are calculated for each IMF. Next, a feature vector is obtained for each faulty circuit. Finally, an ELM classifier is trained with these feature vectors for fault diagnosis. Via validating with two benchmark circuits, results show that the proposed method is applicable for analog fault diagnosis with acceptable levels of accuracy and time cost.

  4. An AST-ELM Method for Eliminating the Influence of Charging Phenomenon on ECT.

    Science.gov (United States)

    Wang, Xiaoxin; Hu, Hongli; Jia, Huiqin; Tang, Kaihao

    2017-12-09

    Electrical capacitance tomography (ECT) is a promising imaging technology of permittivity distributions in multiphase flow. To reduce the effect of charging phenomenon on ECT measurement, an improved extreme learning machine method combined with adaptive soft-thresholding (AST-ELM) is presented and studied for image reconstruction. This method can provide a nonlinear mapping model between the capacitance values and medium distributions by using machine learning but not an electromagnetic-sensitive mechanism. Both simulation and experimental tests are carried out to validate the performance of the presented method, and reconstructed images are evaluated by relative error and correlation coefficient. The results have illustrated that the image reconstruction accuracy by the proposed AST-ELM method has greatly improved than that by the conventional methods under the condition with charging object.

  5. An AST-ELM Method for Eliminating the Influence of Charging Phenomenon on ECT

    Directory of Open Access Journals (Sweden)

    Xiaoxin Wang

    2017-12-01

    Full Text Available Electrical capacitance tomography (ECT is a promising imaging technology of permittivity distributions in multiphase flow. To reduce the effect of charging phenomenon on ECT measurement, an improved extreme learning machine method combined with adaptive soft-thresholding (AST-ELM is presented and studied for image reconstruction. This method can provide a nonlinear mapping model between the capacitance values and medium distributions by using machine learning but not an electromagnetic-sensitive mechanism. Both simulation and experimental tests are carried out to validate the performance of the presented method, and reconstructed images are evaluated by relative error and correlation coefficient. The results have illustrated that the image reconstruction accuracy by the proposed AST-ELM method has greatly improved than that by the conventional methods under the condition with charging object.

  6. Computer aided diagnosis of schizophrenia on resting state fMRI data by ensembles of ELM.

    Science.gov (United States)

    Chyzhyk, Darya; Savio, Alexandre; Graña, Manuel

    2015-08-01

    Resting state functional Magnetic Resonance Imaging (rs-fMRI) is increasingly used for the identification of image biomarkers of brain diseases or psychiatric conditions such as schizophrenia. This paper deals with the application of ensembles of Extreme Learning Machines (ELM) to build Computer Aided Diagnosis systems on the basis of features extracted from the activity measures computed over rs-fMRI data. The power of ELM to provide quick but near optimal solutions to the training of Single Layer Feedforward Networks (SLFN) allows extensive exploration of discriminative power of feature spaces in affordable time with off-the-shelf computational resources. Exploration is performed in this paper by an evolutionary search approach that has found functional activity map features allowing to achieve quite successful classification experiments, providing biologically plausible voxel-site localizations. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Neonicotinoid insecticide imidacloprid causes outbreaks of spider mites on elm trees in urban landscapes.

    Directory of Open Access Journals (Sweden)

    Adrianna Szczepaniec

    Full Text Available BACKGROUND: Attempts to eradicate alien arthropods often require pesticide applications. An effort to remove an alien beetle from Central Park in New York City, USA, resulted in widespread treatments of trees with the neonicotinoid insecticide imidacloprid. Imidacloprid's systemic activity and mode of entry via roots or trunk injections reduce risk of environmental contamination and limit exposure of non-target organisms to pesticide residues. However, unexpected outbreaks of a formerly innocuous herbivore, Tetranychus schoenei (Acari: Tetranychidae, followed imidacloprid applications to elms in Central Park. This undesirable outcome necessitated an assessment of imidacloprid's impact on communities of arthropods, its effects on predators, and enhancement of the performance of T. schoenei. METHODOLOGY/PRINCIPAL FINDINGS: By sampling arthropods in elm canopies over three years in two locations, we document changes in the structure of communities following applications of imidacloprid. Differences in community structure were mostly attributable to increases in the abundance of T. schoenei on elms treated with imidacloprid. In laboratory experiments, predators of T. schoenei were poisoned through ingestion of prey exposed to imidacloprid. Imidacloprid's proclivity to elevate fecundity of T. schoenei also contributed to their elevated densities on treated elms. CONCLUSIONS/SIGNIFICANCE: This is the first study to report the effects of pesticide applications on the arthropod communities in urban landscapes and demonstrate that imidacloprid increases spider mite fecundity through a plant-mediated mechanism. Laboratory experiments provide evidence that imidacloprid debilitates insect predators of spider mites suggesting that relaxation of top-down regulation combined with enhanced reproduction promoted a non-target herbivore to pest status. With global commerce accelerating the incidence of arthropod invasions, prophylactic applications of pesticides

  8. Characterization of turbulence in L- and ELM-free H-mode Wendelstein 7-AS plasmas

    Science.gov (United States)

    Basse, N. P.; Zoletnik, S.; Antar, G. Y.; Baldzuhn, J.; Werner, A.; W7-AS Team

    2003-04-01

    In this paper, measurements of small scale electron density fluctuations in low confinement (L)-mode and high confinement (H)-mode plasmas obtained by collective scattering of infrared light are presented. A single discharge in the Wendelstein 7-AS (W7-AS) stellarator (Renner H et al 1989 Plasma Phys. Control. Fusion 31 1579) was studied. The plasma developed from steady-state L-mode to a dithering mode and finally became an edge localized mode (ELM)-free H-mode. These three phases are separately characterized. Autopower spectra of density fluctuations measured in the dithering and ELM-free H-modes are limited to lower frequencies than those in the dithering and steady-state L-modes. Correlations between the density fluctuations, an Halpha-signal and magnetic fluctuations as measured by Mirnov coils were analysed. The correlation calculations made for time windows of tens of milliseconds with time lag steps of 100 mus show that all the fluctuating quantities are highly correlated during the L-mode and dithering states, but that no correlation exists in the ELM-free H-mode. Evaluating correlations on a 20 mus timescale between magnetic and density fluctuations leads to the result that the minimum correlation timescale in steady-state and dithering L-modes is of order 100 mus, while no correlation exists for ELM-free and dithering H-modes. Finally, the time derivative of the phase of the measured complex density fluctuation signal allows us to study the structure of turbulent bursts in L- and H-mode.

  9. Ion orbit modelling of ELM heat loads on ITER divertor vertical targets.

    Czech Academy of Sciences Publication Activity Database

    Gunn, J. P.; Carpentier-Chouchana, S.; Dejarnac, Renaud; Escourbiac, F.; Hirai, T.; Komm, Michael; Kukushkin, A.; Panayotis, S.; Pitts, R.A.

    2017-01-01

    Roč. 12, August (2017), s. 75-83 ISSN 2352-1791. [International Conference on Plasma Surface Interactions 2016, PSI2016 /22./. Roma, 30.05.2016-03.06.2016] Institutional support: RVO:61389021 Keywords : ITER * Divertor * ELM heat loads Subject RIV: BL - Plasma and Gas Discharge Physics OBOR OECD: Fluids and plasma physics (including surface physics) http://www.sciencedirect.com/science/article/pii/S2352179116302745

  10. Latest investigations on fluctuations, ELM filaments and turbulent transport in the SOL of ASDEX Upgrade

    Czech Academy of Sciences Publication Activity Database

    Müller, H. W.; Adámek, Jiří; Cavazzana, R.; Conway, G.D.; Fuchs, C.; Gunn, J. P.; Herrmann, A.; Horáček, Jan; Ionita, C.; Kallenbach, A.; Kočan, M.; Maraschek, M.; Maszl, C.; Mehlmann, F.; Nold, B.; Peterka, M.; Rohde, V.; Schweinzer, J.; Schrittwieser, R.; Vianello, N.; Wolfrum, E.; Zuin, M.

    2011-01-01

    Roč. 51, č. 7 (2011), 073023-073023 ISSN 0029-5515 R&D Projects: GA AV ČR KJB100430901 Institutional research plan: CEZ:AV0Z20430508 Keywords : SOL * ASDEX * ELM * tokamak * ball- pen * H-mode Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 4.090, year: 2011 http://iopscience.iop.org/0029-5515/51/7/073023/pdf/0029-5515_51_7_073023.pdf

  11. External kink modes as a model for MHD activity associated with ELMs

    Energy Technology Data Exchange (ETDEWEB)

    Manickam, J.

    1992-01-01

    Tokamak plasmas in the high confinement mode of operation are known to exhibit edge localized activity referred to as ELMs. A model is proposed for the underlying cause in terms of the external kink mode. The build up of the current density near the plasma edge is shown to decrease the shear in the safety-factor, q, profile and lead to destabilization of the kink mode. The role of the plasma geometry and equilibrium profiles is discussed.

  12. Pedestal structure and inter-ELM evolution for different main ion species in ASDEX Upgrade

    Science.gov (United States)

    Laggner, F. M.; Wolfrum, E.; Cavedon, M.; Mink, F.; Bernert, M.; Dunne, M. G.; Schneider, P. A.; Kappatou, A.; Birkenmeier, G.; Fischer, R.; Willensdorfer, M.; Aumayr, F.

    2017-05-01

    In tokamak plasmas with different main ion species, a change in confinement occurs, known as the isotope effect. Experiments comparing hydrogen (H), deuterium (D), and helium (4He) plasmas have been performed to identify processes that define the pedestal structure and evolution in between the crashes of edge localized modes (ELMs). The pedestal top electron densities and temperatures have been matched to compare the pedestal shape and stability. In the D and H discharges, the pedestal electron temperature profiles do not differ, whereas the density profile in H has shallower gradients. Furthermore, the heat flux across the pedestal in H is roughly a factor of two higher than in D. In 4He plasmas at similar stored energy, the pedestal top electron density is roughly a factor of 1.5 larger than in the references owing to the larger effective charge. The peeling-ballooning theory, which is independent of the main ion species mass, can sufficiently describe the pedestal stability in the hydrogenic plasmas. The inter-ELM pedestal evolution has the same sequence of recovery phases for all investigated species, giving evidence that similar mechanisms are acting in the pedestals. This is further supported by a similar evolution of the inter-ELM magnetic signature and the corresponding toroidal structure.

  13. Thr202Ala in thyA Is a Marker for the Latin American Mediterranean Lineage of the Mycobacterium tuberculosis Complex Rather than Para-Aminosalicylic Acid Resistance

    KAUST Repository

    Feuerriegel, S.

    2010-08-30

    Single nucleotide polymorphisms (SNPs) involved in the development of resistance represent powerful markers for the rapid detection of first- and second-line resistance in clinical Mycobacterium tuberculosis complex (MTBC) isolates. However, the association between particular mutations and phenotypic resistance is not always clear-cut, and phylogenetic SNPs have been misclassified as resistance markers in the past. In the present study, we investigated the utility of a specific polymorphism in thyA (Thr202Ala) as a marker for resistance to para-aminosalicyclic acid (PAS). Sixty-three PAS-susceptible MTBC strains comprising all major phylogenetic lineages, reference strain H37Rv, and 135 multidrug-resistant (MDR) strains from Germany (comprising 8 PAS-resistant isolates) were investigated for the presence of Thr202Ala. In both strain collections, the Thr202Ala SNP was found exclusively in strains of the Latin American Mediterranean (LAM) lineage irrespective of PAS resistance. Furthermore, PAS MICs (0.5 mg/liter) for selected LAM strains (all containing the SNP) and non-LAM strains (not containing the SNP), as well as the results of growth curve analyses performed in liquid 7H9 medium in the presence of increasing PAS concentrations (0 to 2.0 mg/liter), were identical. In conclusion, our data demonstrate that the Thr202Ala polymorphism in thyA is not a valid marker for PAS resistance but, instead, represents a phylogenetic marker for the LAM lineage of the M. tuberculosis complex. These findings challenge some of the previous understanding of PAS resistance and, as a consequence, warrant further in-depth investigations of the genetic variation in PAS-resistant clinical isolates and spontaneous mutants.

  14. Physics of increased edge electron temperature and density turbulence during ELM-free QH-mode operation on DIII-D

    Science.gov (United States)

    Sung, C.; Rhodes, T. L.; Staebler, G. M.; Yan, Z.; McKee, G. R.; Smith, S. P.; Osborne, T. H.; Peebles, W. A.

    2018-05-01

    For the first time, we report increased edge electron temperature and density turbulence levels ( T˜ e and n˜ e) in Edge Localized Mode free Quiescent H-mode (ELM-free QH-mode) plasmas as compared to the ELMing time period. ELMs can severely damage plasma facing components in fusion plasma devices due to their large transient energy transport, making ELM-free operation a highly sought after goal. The QH-mode is a candidate for this goal as it is ELM-free for times limited only by hardware constraints. It is found that the driving gradients decrease during the QH-mode compared to the ELMing phase, however, a significant decrease in the ExB shearing rate is also observed that taken together is consistent with the increased turbulence. These results are significant as the prediction and control of ELM-free H-mode regimes are crucial for the operation of future fusion devices such as ITER. The changes in the linear growth rates calculated by CGYRO [Candy et al., J. Comput. Phys. 324, 73 (2016)] and the measured ExB shearing rate between ELMing and QH-mode phases are qualitatively consistent with these turbulence changes. Comparison with ELMing and 3D fields ELM suppressed H-mode finds a similar increase in T˜ e and n˜ e, however, with distinctly different origins, the increased driving gradients rather than the changes in the ExB shearing rate in 3D fields ELM suppressed the H-mode. However, linear gyrokinetic calculation results are generally consistent with the increased turbulence in both ELM-controlled discharges.

  15. Dendrometric, phytopathological and entomological characteristics of a wych elm tree on mt. Goč

    Directory of Open Access Journals (Sweden)

    Medarević Milan

    2011-01-01

    Full Text Available Valuable broadleaves, including also wych elms, belong to the category of rare tree species in the growing stock of Serbia. The conservation of Serbian forest diversity and the genetic potential of these tree species require a multidisciplinary study. In this respect, we undertook a dendrometric and health analysis of a wych elm tree on Goč, as it is a rarity by its dimensions, not only from the local, but also from the regional aspects. The tree is 266 years old, its diameter at breast height is 2.09 m, height 42.1 m, and volume (d>3 cm 56.35 m3. Current height increment culminated early, at the age of 20-30 years, attaining 0.5 m, and current diameter increment at the age of 40-50 years when its value was 14.4 mm. The above data point to a high productivity of this elm tree and to favourable site and stand conditions of its development. On the other hand, its current diameter increment and height over the last period (1.7 mm, and 0.03 m respectively indicate that the tree was in the phase of physiological dying. 10 species of fungi were identified on the tree (facultative parasites or saprophytes, the most significant being Armillaria mellea and Aurantioporus fissilis, which caused central heartwood decay. Other fungi developed saprophytically in the dead part of the stem or in dead branches. Eight insect species (secondary and tertiary pests were identified, including the two most dangerous elm beetles (Scolytus scolytus and S. multistriatus. Together with the species Saperda punctata and Cerambyx scopolii, they accelerated the dying process of twigs and branches, as well as of the whole tree. Ambrosia beetle Xyleborus monographus infested the stem and the large dead branches and caused minor technical damage in wood. The species Dorcus paralelopipedus, Oryctes nasicornis and Valgus hemipterus supported the faster progress of wood-rotting fungi and thus contributed to physiological weakening and shortened the life cycle of the study elm tree.

  16. Impact of impurity seeding and divertor conditions on transitions, pedestal structure and ELMs

    Science.gov (United States)

    Dunne, M. G.

    2017-02-01

    Future devices will require a high scrape-off later (SOL) density and impurity seeding to avoid high-Z sputtering. However, these operational parameters are not included in present-day scaling laws, making extrapolations to larger devices difficult. As such, understanding the physics of such effects is vital in order to design the operational scenarios most favorable to high fusion gain. This review presents the favorable lowering of L-H transition power by changing to metal walled devices and sumarises the effects currently thought to be responsible for how SOL geometry can play a role in determining this threshold. Experimental observations on changes to the pedestal structure with main ion fuelling and low-, medium-, and high-Z impurity seeding are presented. These results, from several devices, show that main ion fuelling or high density operation can result in a lower pedestal top pressure, and hence reduced stored energy, while impurity seeding can recover this lost pressure. Particular focus is given to nitrogen seeded discharges and the recovery of pedestal parameters (notably high {{T}\\text{e,\\text{ped}}} ) in JET and AUG since the changeover to metal walls in these devices. Lithium seeding is also emerging as a strong actuator in pedestal dynamics, with results ranging from a prolonged inter-ELM period to completely ELM-free scenarios on different devices. ELM dynamics are also presented in each section, with nitrogen seeding offering a probe into the structure of the ELM and demonstrating the difference between the initial ELM crash, likely due to a sharp MHD event, and a prolonged second phase, the origin of which remains unkown. Finally, modelling of the pedestal in impurity seeded scenarios reveals a common effect in the position of the density profile. Either through mode excitation near to the separatrix or an altered fuelling profile, seeding of impurities results in an inward shift of the density profile. This inward shift improves MHD stability

  17. "Fool Me Once, Shame on You; Fool Me Twice, Shame on Me": African American Students' Reclamation of Smartness as Resistance

    Science.gov (United States)

    Twyman Hoff, Pamela

    2016-01-01

    In African American culture competing value systems shape the definition and value of smartness. This article will explore African American "sayins" as a tool to transmit the counter-hegemonic cultural value of smartness. "Sayins," a facet of the African American oral tradition, are drawn from the deep structures of African…

  18. Repetitive plasma loads typical for ITER Type-I ELMS; simulation in QSPA Kh-50

    International Nuclear Information System (INIS)

    Tereshin, V.I.; Bandura, A.N.; Byrka, O.V.; Chebotarev, V.V.; Garkusha, I.E.; Makhlaj, V.A.; Solyakov, D.G.; Tsarenko, A.V.; Landman, I.

    2005-01-01

    The power loads on current tokamaks associated with the Type I ELMs generally do not affect the lifetime of divertor elements. However, the ITER ELMs may lead to unacceptable lifetime; their loads are estimated as QELM(1-3) MJ/m 2 at t = 0.1-1 ms and the repetition frequency of an order of 1 Hz (∼ 400 ELMs during each ITER pulse). Such plasma energy loads expected for ITER ELMs are not achieved in existing tokamaks. Therefore powerful plasma accelerators are used at present for study of plasma-target interaction and for numerical models validation. Quasi-steady-state plasma accelerators (QSPA), which characterized by essentially longer duration of plasma stream generation in comparison with pulsed plasma guns, became especially attractive facilities for investigations of plasma-surface interaction in conditions of high heat loads simulating the ITER disruptions and ELMs. The paper presents experimental study of energy characteristics of the plasma streams generated with quasi-steady-state plasma accelerator QSPA Kh-50 and the main features of plasma interaction with material surfaces in dependence on plasma heat loads. The samples of pure sintered tungsten of EU trademark have been exposed to hydrogen plasma streams produced by the accelerator. To estimate the range of tolerable loads the effects of ELMs on the lifetime of plasma facing components have been experimentally simulated for large numbers of impacts with varying energy density. The experiments were performed with up to 450 pulses of the duration of 0.25 ms and the heat loads in the range of 0.5 - 1.2 MJ/m 2 . At this calorimetry (both at plasma stream and at the target surface), piezo-detectors as well as spectroscopy and interferometry measurements were applied to determine the impacting plasma parameters in different regimes of operation. A threshold character of morphological changes on the tungsten surface under the melting in respect to the pulses number is demonstrated. The number of initial

  19. Suppression of Type-I ELMs with a Reduced I-coil Set in DIII-D

    Science.gov (United States)

    Orlov, D. M.

    2013-10-01

    Recent experiments in DIII-D have demonstrated that Edge Localized Modes (ELMs) in a tokamak can be controlled with a reduced number of magnetic perturbation coils, demonstrating an important role of spectral sidebands, and showing promise of the technique for future fusion devices, where ELMs risk potentially damaging heat loads. The ELMs can be controlled with external magnetic perturbation used to regulate pressure gradients and maintain stability. The new results show that the coil currents required for ELM suppression with the reduced coil sets are comparable to what is typically required for the full set. This counterintuitive result provides an important validation of recent modeling of the physical mechanisms involved. This modeling shows that the spectral sidebands introduced by deactivating individual coils can often increase the magnetic stochasticity within the plasma, thereby increasing transport and facilitating ELM suppression. Deactivating individual coils results not only in the reduction of the dominant n = 3 component of the perturbation field, but also in a significant increase in the amplitudes of n = 1 and n = 2 sidebands. These sidebands may also be amplified by the plasma response. Application to ITER finds that the ITER ELM coils may be able to tolerate a loss of up to five of its 27 coils, while leaving a sufficient margin of current in the remaining coils to still meet the DIII-D ELM suppression criterion. Further, the new experiments show that the presence of the spectral sidebands does not adversely affect the plasma rotation or confinement. Both vacuum and two-fluid modeling are used to interpret and understand these results. Supported by US DOE under DE-FG02-05ER54809 & DE-FC02-04ER54698.

  20. Effects of turf and cleat footwear on plantar load distributions in adolescent American football players during resisted pushing.

    Science.gov (United States)

    Taylor, Jeffrey B; Nguyen, Anh-Dung; Griffin, Janet R; Ford, Kevin R

    2018-06-01

    Metatarsal and midfoot injuries are common in American football. Footwear design may influence injury rates by altering plantar foot loading patterns in these regions. The purpose of this study was to determine the effect of cleat design on in-shoe plantar foot loading during a football-specific, resisted pushing task. Twenty competitive football players (age 14.7 ± 1.8 years, height 1.72 ± 0.10 m, and mass 71.8 ± 26.9 kg) completed three trials of pushing a weighted sled at maximal effort in a standard shoe (CLEAT) and artificial turf-specific shoe (TURF), with flexible in-shoe force measuring insoles. Repeated measures ANOVAs identified mean differences in maximum force and relative load under all regions of the foot. Results showed higher forces in the CLEAT under the medial (p < 0.001) and lateral (p = 0.004) midfoot, central (p = 0.007) and lateral (p < 0.001) forefoot, and lesser toes (p = 0.01), but lower forces in the hallux (p = 0.02) compared to the TURF shoe. Additionally, relative loading was higher in the CLEAT under the medial (p < 0.001) and lateral (p = 0.002) midfoot and lateral (p < 0.001) forefoot, but lower in the medial forefoot (p = 0.006) and hallux (p < 0.001) compared to the TURF shoe. The two shoes elicited distinct plantar loading profiles and may influence shoe selection decisions during injury prevention or rehabilitation practices.

  1. Association mapping of North American spring wheat breeding germplasm reveals loci conferring resistance to Ug99 and other African stem rust races.

    Science.gov (United States)

    Bajgain, P; Rouse, M N; Bulli, P; Bhavani, S; Gordon, T; Wanyera, R; Njau, P N; Legesse, W; Anderson, J A; Pumphrey, M O

    2015-10-14

    also identified putatively novel Sr resistance genes on chromosomes 3B, 4D, 5A, 5B, 6A, 7A, and 7B. Our results demonstrate that the North American wheat breeding lines have several resistance loci that provide APR and seedling resistance to highly virulent Pgt races. Using the resistant lines and the SNP markers identified in this study, marker-assisted resistance breeding can assist in development of varieties with elevated levels of resistance to virulent stem rust races including TTKSK.

  2. Cytotoxicity of medicinal plants of the West-Canadian Gwich׳in Native Americans towards sensitive and multidrug-resistant cancer cells.

    Science.gov (United States)

    Karadeniz, Asuman; Alexie, Gladys; Greten, Henry Johannes; Andersch, Kai; Efferth, Thomas

    2015-06-20

    Traditional medicine of the Native Americans has a long tradition of medicinal plants, which also influenced modern oncology. For instance, podophyllotoxin the active ingredient of Podophyllum peltatum L. (Berberidaceae) used by Native Americans to treat warts led to the development of etoposide and teniposide. In the present investigation, we studied 10 medicinal plants used by the Gwich׳in First Nation of West-Canada, which have been used against diverse diseases including cancer. Sensitive and multidrug-resistant (MDR) tumor cell lines expressing various ATP-binding cassette (ABC) transporters (P-glycoprotein/ABCB1/MDR1, MRP1/ABCC1, or BCRP/ABCG2) have been used. Cytotoxicity was determined by the resazurin assay. Arctium minus Bernh. (Asteraceae). Lysichiton americanus Hultén & St. John (Araceae), and Maianthemum dilatatum (Alph.Wood) A.Nelson & J.F.Macbr.(Asparagaceae) were cytotoxic with IC50 values ranging from 2.40 to 86.35 µg/mL. The MDR cell lines did not exert cross-resistance to these extracts. As these medicinal plants of the West-Canadian Gwich׳in First Nation were not involved in classical drug resistance mechanisms and might therefore be valuable to bypass anticancer drug resistance in refractory tumors. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  3. ELMs and constraints on the H-mode pedestal: A model based on peeling-ballooning modes

    International Nuclear Information System (INIS)

    Snyder, P.B.; Ferron, J.R.; Wilson, H.R.

    2003-01-01

    We propose a model for Edge Localized Modes (ELMs) and pedestal constraint based upon theoretical analysis of instabilities which can limit the pedestal height and drive ELMs. The sharp pressure gradients, and resulting bootstrap current, in the pedestal region provide free energy to drive peeling and ballooning modes. The interaction of peeling-ballooning coupling, ballooning mode second stability, and finite-Larmor-radius effects results in coupled peeling-ballooning modes of intermediate wavelength generally being the limiting instability. A highly efficient new MHD code, ELITE, is used to calculate quantitative stability constraints on the pedestal, including con straits on the pedestal height. Because of the impact of collisionality on the bootstrap current, these pedestal constraints are dependant on the density and temperature separately, rather than simply on the pressure. A model of various ELM types is developed, and quantitatively compared to data. A number of observations agree with predictions, including ELM onset times, ELM depth and variation in pedestal height with collisionality and discharge shape. Stability analysis of series of model equilibria are used both o predict and interpret pedestal trends in existing experiments and to project pedestal constraints for future burning plasma tokamak designs. (author)

  4. A novel genetic screen implicates Elm1 in the inactivation of the yeast transcription factor SBF.

    Directory of Open Access Journals (Sweden)

    Emily N Manderson

    Full Text Available BACKGROUND: Despite extensive large scale analyses of expression and protein-protein interactions (PPI in the model organism Saccharomyces cerevisiae, over a thousand yeast genes remain uncharacterized. We have developed a novel strategy in yeast that directly combines genetics with proteomics in the same screen to assign function to proteins based on the observation of genetic perturbations of sentinel protein interactions (GePPI. As proof of principle of the GePPI screen, we applied it to identify proteins involved in the regulation of an important yeast cell cycle transcription factor, SBF that activates gene expression during G1 and S phase. METHODOLOGY/PRINCIPLE FINDINGS: The principle of GePPI is that if a protein is involved in a pathway of interest, deletion of the corresponding gene will result in perturbation of sentinel PPIs that report on the activity of the pathway. We created a fluorescent protein-fragment complementation assay (PCA to detect the interaction between Cdc28 and Swi4, which leads to the inactivation of SBF. The PCA signal was quantified by microscopy and image analysis in deletion strains corresponding to 25 candidate genes that are periodically expressed during the cell cycle and are substrates of Cdc28. We showed that the serine-threonine kinase Elm1 plays a role in the inactivation of SBF and that phosphorylation of Elm1 by Cdc28 may be a mechanism to inactivate Elm1 upon completion of mitosis. CONCLUSIONS/SIGNIFICANCE: Our findings demonstrate that GePPI is an effective strategy to directly link proteins of known or unknown function to a specific biological pathway of interest. The ease in generating PCA assays for any protein interaction and the availability of the yeast deletion strain collection allows GePPI to be applied to any cellular network. In addition, the high degree of conservation between yeast and mammalian proteins and pathways suggest GePPI could be used to generate insight into human disease.

  5. THE ELM SURVEY. I. A COMPLETE SAMPLE OF EXTREMELY LOW-MASS WHITE DWARFS

    International Nuclear Information System (INIS)

    Brown, Warren R.; Kilic, Mukremin; Kenyon, Scott J.; Prieto, Carlos Allende

    2010-01-01

    We analyze radial velocity observations of the 12 extremely low-mass (ELM), with ≤0.25 M sun , white dwarfs (WDs) in the MMT Hypervelocity Star Survey. Eleven of the twelve WDs are binaries with orbital periods shorter than 14 hr; the one non-variable WD is possibly a pole-on system among our non-kinematically selected targets. Our sample is unique: it is complete in a well-defined range of apparent magnitude and color. The orbital mass functions imply that the unseen companions are most likely other WDs, although neutron star companions cannot be excluded. Six of the eleven systems with orbital solutions will merge within a Hubble time due to the loss of angular momentum through gravitational wave radiation. The quickest merger is J0923+3028, a g = 15.7 ELM WD binary with a 1.08 hr orbital period and a ≤130 Myr merger time. The chance of a supernova Ia event among our ELM WDs is only 1%-7%, however. Three binary systems (J0755+4906, J1233+1602, and J2119-0018) have extreme mass ratios and will most likely form stable mass-transfer AM CVn systems. Two of these objects, SDSS J1233+1602 and J2119-0018, are the lowest surface gravity WDs ever found; both show Ca II absorption likely from accretion of circumbinary material. We predict that at least one of our WDs is an eclipsing detached double WD system, important for constraining helium core WD models.

  6. Characteristics of the TFTR limiter H-mode: The transition, ELMs, transport and confinement

    International Nuclear Information System (INIS)

    Bush, C.E.; Bretz, N.; Nazikian, R.; Stratton, B.C.; Synakowski, E.; Taylor, G. Budny, R.; Ramsey, A.T.; Scott, S.D.; Bell, M.; Bell, R.; Biglari, H.; Bitter, M.; Darrow, D.S.; Efthimion, P.; Fredrickson, E.D.; Hill, K.; Hsuan, H.; Kilpatrick, S.; McGuire, K.M.; Manos, D.; Mansfield, D.; Medley, S.S.; Mueller, D.; Park, H.; Paul, S.; Sabbagh, S.; Schivell, J.; Thompson, M.; Towner, H.H.; Wieland, R.M.; Zarnstorff, M.C.; Zweben, S.; Nagayama, Y.

    1992-11-01

    H-Modes obtained through transitions from the supershot regime have been studied on TFTR. The characteristics of these H-modes are similar to those found on other tokamaks with one main exception, the density prof:des can be highly peaked. In the best cases the enhanced confinement in the core of the initial supershot is retained in the H-mode phase, while the confinement in a broad edge region is enhanced. Thus in TFTR, all of the important physics of H-modes such as transitions, enhanced edge confinement, ELMs and other phenomena are studied in a large circular limiter tokamak with the added feature of centrally peaked density profiles and the advantage of an extensive set of diagnostics. The threshold power for the transition is found to be a linear function of plasma current. Transitions and ELMs are affected by the mix of co-and counter-neutral beam injection (NBI) and by perturbations introduced by pellet injection, gas puffing, and current ramping before and during NBI. Fluctuations near both transition and ELM events have been characterized. High frequency magnetic fluctuations in the range ≥ 100--250 kHz usually decrease during the transition. Microwave scattering spectra of density fluctuations in the plasma edge show a feature at high frequency during the H-mode, which is not observed in the plasma core and which is consistent with an edge poloidal rotation velocity, V θ , of ∼ 10 4 m/s. The fluctuations begin at the transition, propagate in the direction of electron diamagnetic drift, and have modulation correlated with ELMs. Several TFTR H-modes showed a modest improvement in confinement over that of the supershots from which they originated, and an understanding of these may eventually lead to a plasma with the combined advantages of both the supershot and the H-mode. The characteristics and physics of the TFTR H-modes are considered relative to other tokamaks and in light of various theoretical studies

  7. On the asymmetries of ELM divertor power deposition in JET and ASDEX Upgrade

    DEFF Research Database (Denmark)

    Eich, T.; Kallenbach, A.; Fundamenski, W.

    2009-01-01

    An analytical expression was derived for describing the divertor target power during ELMs based on the model discussed in [W. Fundamenski, R.A. Pitts, Plasma Phys. Control. Fus. 48 (2006) 109] where the power load arises from a Maxwellian distribution of particles released into the SOL region....... The paper discusses a comparable simple extension of the model by introducing a non-zero characteristic velocity of the Maxwellian distributed particles. This way the experimentally observed temporal evolution as well as the in/out energy imbalance can be described. The extended model named free...

  8. Comparisons of small ELM H-Mode regimes on the Alcator C-Mod and JFT-2M tokamaks

    International Nuclear Information System (INIS)

    Hubbard, A E; Kamiya, K; Oyama, N; Basse, N; Biewer, T; Edlund, E; Hughes, J W; Lin, L; Porkolab, M; Rowan, W; Snipes, J; Terry, J; Wolfe, S M

    2006-01-01

    Comparisons of H-mode regimes were carried out on the Alcator C-Mod and JFT-2M tokamaks. Shapes were matched apart from aspect ratio, which is lower on C-Mod. The high recycling steady H-mode on JFT-2M and enhanced D-alpha (EDA) regime on C-Mod, both of which feature very small or no ELMs, are found to have similar access conditions in q 95 - ν* space, occurring for pedestal collisionality ν* > 1. Differences in edge fluctuations were found, with lower frequencies but higher mode numbers on C-Mod. In both tokamaks an attractive regime with small ELMs on top of an enhanced D α baseline was obtained at moderate ν* and higher pressure. The JFT-2M shape favoured the appearance of ELMs on C-Mod and also resulted in the appearance of a lower frequency component of the quasicoherent mode during EDA

  9. Program ELM: A tool for rapid thermal-hydraulic analysis of solid-core nuclear rocket fuel elements

    Science.gov (United States)

    Walton, James T.

    1992-01-01

    This report reviews the state of the art of thermal-hydraulic analysis codes and presents a new code, Program ELM, for analysis of fuel elements. ELM is a concise computational tool for modeling the steady-state thermal-hydraulics of propellant flow through fuel element coolant channels in a nuclear thermal rocket reactor with axial coolant passages. The program was developed as a tool to swiftly evaluate various heat transfer coefficient and friction factor correlations generated for turbulent pipe flow with heat addition which have been used in previous programs. Thus, a consistent comparison of these correlations was performed, as well as a comparison with data from the NRX reactor experiments from the Nuclear Engine for Rocket Vehicle Applications (NERVA) project. This report describes the ELM Program algorithm, input/output, and validation efforts and provides a listing of the code.

  10. Host Acceptance and Larval Competition between the Invasive Banded and European Elm Bark Beetles, Scolytus schevyrewi and S. multistriatus (Coleoptera: Scolytidae): Potential Mechanisms for Competitive Displacement

    Science.gov (United States)

    A recent survey revealed that the newly invasive banded elm bark beetle, Scolytus schevyrewi, was much more abundant than the long-established European elm bark beetle, S. multistriatus, in areas of Colorado and Wyoming, USA. This study sought to determine whether competitive displacement of S. mul...

  11. A native QTL for Fusarium head blight resistance in North American barley (Hordeum vulgare L.) independent of height, maturity, and spike type loci.

    Science.gov (United States)

    Yu, G T; Franckowiak, J D; Neate, S M; Zhang, B; Horsley, R D

    2010-02-01

    Fusarium head blight (FHB), caused by Fusarium graminearum Schwabe (teleomorph Gibberella zeae (Schwein.) Petch), is one of the major diseases of barley (Hordeum vulgare L.) in eastern China, the Upper Midwest of the USA, and the eastern Prairie Provinces of Canada. To identify quantitative trait loci (QTL) controlling FHB resistance, a recombinant inbred line population (F6:7) was developed from the cross Zhenongda 7/PI 643302. The population was phenotyped for resistance to FHB in two experiments in China and four experiments in North Dakota. Accumulation of the mycotoxin deoxynivalenol was determined in one experiment in China and two in North Dakota. Simplified composite interval mapping was performed on the whole genome level using the software MQTL. The QTL FHB-2 from PI 643302 for FHB resistance was found on the distal portion of chromosome 2HL in all six FHB screening environments. This QTL accounted for 14% of phenotypic variation over six environments and was not associated with heading date or plant height. The FHB resistance QTL FHB-2 detected near the end of chromosome 2HL is in a different location from those found previously and is therefore probably unique. Because the QTL was not contributed by the Chinese cultivar Zhenongda 7, it is likely a native QTL present in North American barley. The QTL FHB-2 represents the first reported QTL for native FHB resistance in North American germ plasm and has been given the provisional name Qrgz-2H-14. This QTL should be considered for pyramiding with other FHB QTL previously mapped.

  12. Intrusion detection system using Online Sequence Extreme Learning Machine (OS-ELM) in advanced metering infrastructure of smart grid.

    Science.gov (United States)

    Li, Yuancheng; Qiu, Rixuan; Jing, Sitong

    2018-01-01

    Advanced Metering Infrastructure (AMI) realizes a two-way communication of electricity data through by interconnecting with a computer network as the core component of the smart grid. Meanwhile, it brings many new security threats and the traditional intrusion detection method can't satisfy the security requirements of AMI. In this paper, an intrusion detection system based on Online Sequence Extreme Learning Machine (OS-ELM) is established, which is used to detecting the attack in AMI and carrying out the comparative analysis with other algorithms. Simulation results show that, compared with other intrusion detection methods, intrusion detection method based on OS-ELM is more superior in detection speed and accuracy.

  13. Variability of morphometric characteristics of the leaves of European white elm from the area of Great War Island

    Directory of Open Access Journals (Sweden)

    Devetaković Jovana

    2013-01-01

    Full Text Available The European White Elm (Ulmus effusa Willd. is indicated as a rare and endangered species in the growing stock of the Republic of Serbia. In the area of Great War Island, its natural populations were reduced to 56 registered trees, which occur in three spatially isolated subpopulations. On the basis of the research conducted on the level of variability of adaptible morphometric characteristics of leaves from 14 selected test trees of European White Elm, it can be concluded that the degree of interpopulation variability is satisfactory, which is a good basis for the conservation of the available gene pool.

  14. Comparison of protein profiles of beech bark disease-resistant or beech bark disease-susceptible American beech

    Science.gov (United States)

    Mary E. Mason; Marek Krasowski; Judy Loo; Jennifer. Koch

    2011-01-01

    Proteomic analysis of beech bark proteins from trees resistant and susceptible to beech bark disease (BBD) was conducted. Sixteen trees from eight geographically isolated stands, 10 resistant (healthy) and 6 susceptible (diseased/infested) trees, were studied. The genetic complexity of the sample unit, the sampling across a wide geographic area, and the complexity of...

  15. Experimental assessment of the effects of ELMs and disruptions on ITER divertor armour materials

    International Nuclear Information System (INIS)

    Zhitlukhin, A.M.

    2004-01-01

    Full text: The response of plasma protection materials to thermal energy deposited during simulated Type I Edge Localised Modes (ELMs) and disruptions was studied. The paper describes the design and manufacture of special CFC and tungsten macrobrush targets, the experimental conditions achievable at simulating facilities and results of selected experiments. Experiments are conducted primarily under an EU/RF research collaboration in two plasma guns (QSPA and MK-200UG) located in TRINITI, Troitsk, Russia. The targets were exposed to a large number of repetitive pulses in QSPA plasma gun with heat loads varying in a range of 1-2MJ/m 2 lasting 0.1-0.5ms, with the purpose to determine the total expected erosion rate in ITER. MK-200UG experiments were focused on studying mainly vapor plasma production and impurity transport during ELMs. Moderate tungsten erosion less than 0.3 microns per shot was demonstrated for 1.5MJ/m 2 energy densities. Energy density increasing up to 1.8MJ/m 2 resulted in sharp growth of tungsten erosion, caused by intensive droplet ejection from irradiated tungsten surface. The program of further experiments is discussed. (author)

  16. Simulation of residual thermostress in tungsten after repetitive ELM-like heat loads

    Energy Technology Data Exchange (ETDEWEB)

    Pestchanyi, S., E-mail: serguei.pestchanyi@kit.edu [Karlsruhe Institute of Technology, IHM (Germany); Garkusha, I. [Institute of Plasma Physics of the NSC KIPT, Kharkov (Ukraine); Landman, I. [Karlsruhe Institute of Technology, IHM (Germany)

    2011-10-15

    Brittle destruction of tungsten armour under action of edge localised modes of plasma instabilities (ELMs) in ITER is an important issue determining the lifetime of the divertor. Besides, cracking of the armour produces tungsten dust with characteristic size of 1-10 {mu}m flying from the armour surface with velocities up to 10 m/s. Influx of the tungsten dust into the ITER confinement decreases the temperature of the plasma, reduces the thermonuclear gain and even may run the confinement into disruption. This paper describes experiments in QSPA-Kh50 plasma gun and modeling, which has been performed for providing more insight into the physics of tungsten cracking under action of ELMs and for confirmation of the important result on stabilization of the crack development at the tungsten armour surface, predicted in our previous paper - the same authors, 2010. The threshold value of energy density deposition for start of tungsten cracking has been measured as 0.3 MJ/m{sup 2} after 5-10 shots. From analytical considerations three times smaller threshold value has been predicted with increasing number of shots.

  17. ELM BASED CAD SYSTEM TO CLASSIFY MAMMOGRAMS BY THE COMBINATION OF CLBP AND CONTOURLET

    Directory of Open Access Journals (Sweden)

    S Venkatalakshmi

    2017-05-01

    Full Text Available Breast cancer is a serious life threat to the womanhood, worldwide. Mammography is the promising screening tool, which can show the abnormality being detected. However, the physicians find it difficult to detect the affected regions, as the size of microcalcifications is very small. Hence it would be better, if a CAD system can accompany the physician in detecting the malicious regions. Taking this as a challenge, this paper presents a CAD system for mammogram classification which is proven to be accurate and reliable. The entire work is decomposed into four different stages and the outcome of a phase is passed as the input of the following phase. Initially, the mammogram is pre-processed by adaptive median filter and the segmentation is done by GHFCM. The features are extracted by combining the texture feature descriptors Completed Local Binary Pattern (CLBP and contourlet to frame the feature sets. In the training phase, Extreme Learning Machine (ELM is trained with the feature sets. During the testing phase, the ELM can classify between normal, malignant and benign type of cancer. The performance of the proposed approach is analysed by varying the classifier, feature extractors and parameters of the feature extractor. From the experimental analysis, it is evident that the proposed work outperforms the analogous techniques in terms of accuracy, sensitivity and specificity.

  18. Simulation of residual thermostress in tungsten after repetitive ELM-like heat loads

    International Nuclear Information System (INIS)

    Pestchanyi, S.; Garkusha, I.; Landman, I.

    2011-01-01

    Brittle destruction of tungsten armour under action of edge localised modes of plasma instabilities (ELMs) in ITER is an important issue determining the lifetime of the divertor. Besides, cracking of the armour produces tungsten dust with characteristic size of 1-10 μm flying from the armour surface with velocities up to 10 m/s. Influx of the tungsten dust into the ITER confinement decreases the temperature of the plasma, reduces the thermonuclear gain and even may run the confinement into disruption. This paper describes experiments in QSPA-Kh50 plasma gun and modeling, which has been performed for providing more insight into the physics of tungsten cracking under action of ELMs and for confirmation of the important result on stabilization of the crack development at the tungsten armour surface, predicted in our previous paper - the same authors, 2010. The threshold value of energy density deposition for start of tungsten cracking has been measured as 0.3 MJ/m 2 after 5-10 shots. From analytical considerations three times smaller threshold value has been predicted with increasing number of shots.

  19. Numerical simulations for ITER divertor armour erosion and SOL contamination due to disruptions and ELMs

    International Nuclear Information System (INIS)

    Landman, I.S.; Pestchanyi, S.E.; Bazylev, B.N.

    2005-01-01

    The divertor armour materials for ITER are going to be tungsten (as brushe or plates) and CFC. Disruptive loads with the heat deposition Q up to 30 MJ/m 2 on the time scale τ of 3 ms or operation with ELMs at repetitive loads of Q ∼ 3 MJ/m 2 and τ ∼ 0.3 ms cause enhanced armour erosion and produce contamination of SOL. Recent numerical investigations of erosion mechanisms with the anisotropic thermomechanics code PEGASUS-3D and the surface melt motion code MEMOS-1.5D as well as hot hydrogen plasma dynamics, heat loads at the armour surface and backward propagation of material plasma in SOL with the radiation-magnetohydrodynamics code FOREV-2D are survived. For CFC targets, the local overheating model is explained and numerically demonstrated. For the tungsten targets the numerical analysis of melt motion erosion of W-brushe and bulk tungsten targets on the base of MEMOS-1.5D calculations is developed and accompanied by numerical results. For validation of the codes at the regimes relevant to ITER disruptions and ELMs, the simulation results are compared with available experiments carried out at plasma guns, electron beam test facilities and the tokamak JET. (author)

  20. Experimental assessment of the effects of ELMs and disruptions on ITER divertor armour materials

    International Nuclear Information System (INIS)

    Zhitlukhin, A.; Federici, G.; Giniyatulin, R.; Landman, I.; Linke, J.; Loarte, A.; Merola, M.; Podkovyrov, V.; Safronov, V.

    2005-01-01

    The response of plasma protection materials to thermal energy deposited during simulated Type I Edge Localised Modes (ELMs) and disruptions was studied. The paper describes the design and manufacture of special CFC and tungsten macrobrush targets, the experimental conditions achievable at simulating facilities and results of selected experiments. Experiments are conducted primarily under an EU/RF research collaboration in two plasma guns (QSPA and MK-200UG) located in TRINITI, Troitsk, Russia. The targets were exposed to a large number of repetitive pulses in QSPA plasma gun with heat loads varying in a range of 1-2 MJ/m 2 lasting 0.1-0.5 ms, with the purpose to determine the total expected erosion rate in ITER. MK-200UG experiments were focused on studying mainly vapour plasma production and impurity transport during ELMs. Moderate tungsten erosion less than 0.3 microns per shot was demonstrated for 1.5 MJ/m 2 energy densities. Energy density increasing up to 1.8 MJ/m 2 resulted in sharp growth of tungsten erosion, caused by intensive droplet ejection from irradiated tungsten surface. The program of further experiments is discussed. (author)

  1. Analysis of volatiles induced by oviposition of elm leaf beetle Xanthogaleruca luteola on Ulmus minor.

    Science.gov (United States)

    Wegener, R; Schulz, S; Meiners, T; Hadwich, K; Hilker, M

    2001-03-01

    Egg deposition of the elm leaf beetle Xanthogaleruca luteola causes the emission of volatiles from its food plant, Ulmus minor. These volatiles are exploited by the egg parasitoid, Oomyzus gallerucae, to locate its host. In contrast to other tritrophic systems, the release of volatiles is not induced by feeding but by egg deposition. Previous investigations showed that the release is systemic and can be triggered by jasmonic acid. Comparison of headspace analysis revealed similarities in the blend of volatiles emitted following egg deposition and feeding. The mixture consists of more than 40 compounds; most of the substances are terpenoids. Leaves next to those carrying eggs emit fewer compounds. When treated with jasmonic acid, leaves emit a blend that consists almost exclusively of terpenoids. Dichloromethane extracts of leaves treated with jasmonic acid were also investigated. After separation of extracts of jasmonate induced elm leaves on silica, we obtained a fraction of terpenoid hydrocarbons that was attractive to the parasitoids. This indicates that jasmonic acid stimulates the production of terpenoid hydrocarbons that convey information of egg deposition to the parasitoid.

  2. Assessing the suitability of extreme learning machines (ELM for groundwater level prediction

    Directory of Open Access Journals (Sweden)

    Yadav Basant

    2017-03-01

    Full Text Available Fluctuation of groundwater levels around the world is an important theme in hydrological research. Rising water demand, faulty irrigation practices, mismanagement of soil and uncontrolled exploitation of aquifers are some of the reasons why groundwater levels are fluctuating. In order to effectively manage groundwater resources, it is important to have accurate readings and forecasts of groundwater levels. Due to the uncertain and complex nature of groundwater systems, the development of soft computing techniques (data-driven models in the field of hydrology has significant potential. This study employs two soft computing techniques, namely, extreme learning machine (ELM and support vector machine (SVM to forecast groundwater levels at two observation wells located in Canada. A monthly data set of eight years from 2006 to 2014 consisting of both hydrological and meteorological parameters (rainfall, temperature, evapotranspiration and groundwater level was used for the comparative study of the models. These variables were used in various combinations for univariate and multivariate analysis of the models. The study demonstrates that the proposed ELM model has better forecasting ability compared to the SVM model for monthly groundwater level forecasting.

  3. The History of American Settlement at Camp Atterbury

    Science.gov (United States)

    2010-01-01

    Wisconsinan ice sheet only 10,000 to 16,000 years ago ( Hedge 1997:195). * See...and Shumard’s oaks, with green ash, American elm, sycamore and red maple ( Hedge 1997:195; ERDC/CERL TR-10-3 15 Hoyoma et al. 1985:255). The...solve some of Indiana farmer’s prob- lems during the 1930s. For instance, in the 1930s, soybeans were intro- duced and it became a popular crop. In

  4. Slippery Elm

    Science.gov (United States)

    ... applied to the skin for wounds, burns, gout, rheumatism, cold sores, boils, abscesses, ulcers, toothaches, sore throat, ... wounds. Coughs. Colic. Constipation. Diarrhea. Gout. Hemorrhoids. Herpes. Rheumatism. Stomach ulcers. Syphilis. Tapeworm. Toothache. Urinary tract infections. ...

  5. Genome-wide mutagenesis and multi-drug resistance in American trypanosomes induced by the front-line drug benznidazole

    KAUST Repository

    Campos, Mônica C.

    2017-10-25

    Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and affects 5–8 million people in Latin America. Although the nitroheterocyclic compound benznidazole has been the front-line drug for several decades, treatment failures are common. Benznidazole is a pro-drug and is bio-activated within the parasite by the mitochondrial nitroreductase TcNTR-1, leading to the generation of reactive metabolites that have trypanocidal activity. To better assess drug action and resistance, we sequenced the genomes of T. cruzi Y strain (35.5 Mb) and three benznidazole-resistant clones derived from a single drug-selected population. This revealed the genome-wide accumulation of mutations in the resistant parasites, in addition to variations in DNA copy-number. We observed mutations in DNA repair genes, linked with increased susceptibility to DNA alkylating and inter-strand cross-linking agents. Stop-codon-generating mutations in TcNTR-1 were associated with cross-resistance to other nitroheterocyclic drugs. Unexpectedly, the clones were also highly resistant to the ergosterol biosynthesis inhibitor posaconazole, a drug proposed for use against T. cruzi infections, in combination with benznidazole. Our findings therefore identify the highly mutagenic activity of benznidazole metabolites in T. cruzi, demonstrate that this can result in multi-drug resistance, and indicate that vigilance will be required if benznidazole is used in combination therapy.

  6. Can vessel dimension explain tolerance toward fungal vascular wilt diseases in woody plants? Lessons from Dutch elm disease and esca disease in grapevine.

    Science.gov (United States)

    Pouzoulet, Jérôme; Pivovaroff, Alexandria L; Santiago, Louis S; Rolshausen, Philippe E

    2014-01-01

    This review illuminates key findings in our understanding of grapevine xylem resistance to fungal vascular wilt diseases. Grapevine (Vitis spp.) vascular diseases such as esca, botryosphaeria dieback, and eutypa dieback, are caused by a set of taxonomically unrelated ascomycete fungi. Fungal colonization of the vascular system leads to a decline of the plant host because of a loss of the xylem function and subsequent decrease in hydraulic conductivity. Fungal vascular pathogens use different colonization strategies to invade and kill their host. Vitis vinifera cultivars display different levels of tolerance toward vascular diseases caused by fungi, but the plant defense mechanisms underlying those observations have not been completely elucidated. In this review, we establish a parallel between two vascular diseases, grapevine esca disease and Dutch elm disease, and argue that the former should be viewed as a vascular wilt disease. Plant genotypes exhibit differences in xylem morphology and resistance to fungal pathogens causing vascular wilt diseases. We provide evidence that the susceptibility of three commercial V. vinifera cultivars to esca disease is correlated to large vessel diameter. Additionally, we explore how xylem morphological traits related to water transport are influenced by abiotic factors, and how these might impact host tolerance of vascular wilt fungi. Finally, we explore the utility of this concept for predicting which V. vinifera cultivars are most vulnerable of fungal vascular wilt diseases and propose new strategies for disease management.

  7. Can vessel dimension explain tolerance toward fungal vascular wilt diseases in woody plants? Lessons from Dutch elm disease and esca disease in grapevine.

    Directory of Open Access Journals (Sweden)

    Jerome ePouzoulet

    2014-06-01

    Full Text Available This review illuminates key findings in our understanding of grapevine xylem resistance to fungal vascular wilt diseases. Grapevine (Vitis spp. vascular diseases such as esca, botryosphaeria dieback, and eutypa dieback, are caused by a set of taxonomically unrelated ascomycete fungi. Fungal colonization of the vascular system leads to a decline of the plant host because of a loss of the xylem function and subsequent decrease in hydraulic conductivity. Fungal vascular pathogens use different colonization strategies to invade and kill their host. Vitis vinifera cultivars display different levels of tolerance towards vascular diseases caused by fungi, but the plant defense mechanisms underlying those observations have not been completely elucidated. In this review, we establish a parallel between two vascular diseases, grapevine esca disease and Dutch elm disease, and argue that the former should be viewed as a vascular wilt disease. Plant genotypes exhibit differences in xylem morphology and resistance to fungal pathogens causing vascular wilt diseases. We provide evidence that the susceptibility of three commercial V. vinifera cultivars to esca disease is correlated to large vessel diameter. Additionally, we explore how xylem morphological traits related to water transport are influenced by abiotic factors, and how these might impact host tolerance of vascular wilt fungi. Finally, we explore the utility of this concept for predicting which V. vinifera cultivars are most vulnerable of fungal vascular wilt diseases and propose new strategies for disease management.

  8. Morphological Characteristics and Water-Use Efficiency of Siberian Elm Trees (Ulmus pumila L. within Arid Regions of Northeast Asia

    Directory of Open Access Journals (Sweden)

    Go Eun Park

    2016-11-01

    Full Text Available The Siberian elm (Ulmus pumila L. is one of the most commonly found tree species in arid areas of northeast Asia. To understand the morphological and physiological characteristics of Siberian elms in arid regions, we analyzed leaves from seven study sites (five arid or semi-arid and two mesic in China, Mongolia and the Republic of Korea, which covered a wide range of average annual precipitation (232 mm·year−1 to 1304 mm·year−1 under various aridity indexes (AI and four different microenvironments: sand dune, steppe, riverside and forest. The traits of Siberian elms varied widely along different annual precipitation (P and AI gradients. Tree height (H, leaf size (LS and stomatal area per unit leaf area (AS/AL decreased with increasing AI, whereas leaf mass per unit leaf area (LMA and water-use efficiency (WUE increased significantly. In addition, trees at the five arid sites showed significant differences in LS, LMA and AS/AL but not in H and WUE. Thus, our study indicated that indigenous Siberian elm trees in arid areas have substantially altered their morphological and physiological characteristics to avoid heat stress and increase water conservation in comparison to mesic areas. However, their changes differed depending on the surrounding microenvironment even in arid areas. Trees in sand dunes had a smaller LS, higher LMA, thicker leaf cuticle layer and higher stomatal density and AS than those in steppes and near a riverside.

  9. First report of Geosmithia langdonii and Geosmithia spp. isolated from a decaying elm (Ulmus minor in Geneva, Switzerland

    Directory of Open Access Journals (Sweden)

    Hänzi Martine

    2016-06-01

    Full Text Available The mortality of a young elm Ulmus minor in 2014 in Geneva prompted a search for the microorganisms potentially involved. Symptoms included foliar chlorosis and wilting followed by defoliation of branches. Wood symptoms included a brown streaking of sap wood and brown stains in trunk and branches. The comparison of the resulting ITS rDNA sequences to the NCBI Nucleotide database allowed to identify 10 different organisms. The genus Geosmithia represented 48% of the isolates belonging to three species: Geosmithia langdonii (7 isolates and 2 unknown morphologically and genetically different Geosmithia sp. 1 and sp. 2 (4 isolates. Geosmithia species are very little known ascomycetes, which have been recently shown to be opportunistic pathogens on broadleaved trees and conifers, living as saprobes in galleries of many bark beetle species. In the case described here, Geosmithia langdonii, and the unknown Geosmithia species were found in symptomatic wood while bark beetle galleries were found in close regions of the symptomatic wood. Geosmithia langdonii was the major fungus retrieved from the symptomatic wood and could have contributed, along with other identified fungal species, to a pathogenic complex producing symptoms similar to the ones of the Dutch Elm Disease and led to the dieback of this elm tree. Geosmithia langdonii and 2 yet unknown Geosmithia species (sp. 1 and sp. 2, different from any other reported Geosmithia species are reported from an elm tree in Switzerland for the first time.

  10. Human impact on the genetic diversity of Dutch field elm (Ulmus minor) populations in the Netherlands: implications for conservation

    NARCIS (Netherlands)

    Buiteveld, Joukje; Vanden Broeck, An; Cox, Karen; Collin, Eric

    2016-01-01

    Background and aims – Field elms (Ulmus minor Mill.) can easily reproduce vegetatively by root suckers or sprouting. They also have a long history of propagation and planting in the Netherlands. Both natural vegetative reproduction and cultivation may significantly influence the genetic structure of

  11. Ulmus americana is a polyploid complex

    Science.gov (United States)

    The elms (the genus Ulmus) are one of the most important tree crops for the $4.7-billion per year nursery industry. The commercial importance of the genus centers on the American elm, Ulmus americana. Once decimated by Dutch Elm Disease, the recent introduction of cultivars resistant to the diseas...

  12. Do Trials of Resistance Training to Improve Mobility After Stroke Adhere to the American College of Sports Medicine Guidelines? A Systematic Review.

    Science.gov (United States)

    Hendrey, Genevieve; Holland, Anne E; Mentiplay, Benjamin F; Clark, Ross A; Williams, Gavin

    2018-03-01

    To determine whether resistance training to improve mobility outcomes after stroke adheres to the American College of Sports Medicine (ACSM) guidelines, and whether adherence was associated with better outcomes. Online databases searched from 1975 to October 30, 2016. Randomized controlled trials examining the effectiveness of lower limb strength training on mobility outcomes in adult participants with stroke. Two independent reviewers completed data extraction. Quality of trials was determined using the Cochrane Risk of Bias Tool. Trials were scored based on their protocol's adherence to 8 ACSM recommendations. To determine if a relation existed between total adherence score and effect size, Spearman ρ was calculated, and between individual recommendations and effect size, Mann-Whitney U or Kruskal-Wallis tests were used. Thirty-nine trials met the inclusion criteria, and 34 were scored on their adherence to the guidelines. Adherence was high for frequency of training (100% of studies), but few trials adhered to the guidelines for intensity (32%), specificity (24%), and training pattern (3%). Based on the small number of studies that could be included in pooled analysis (n=12), there was no relation between overall adherence and effect size (Spearman ρ=-.39, P=.21). Adherence to the ACSM guidelines for resistance training after stroke varied widely. Future trials should ensure strength training protocols adhere more closely to the guidelines, to ensure their effectiveness in stroke can be accurately determined. Copyright © 2017 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  13. HIV Drug Resistance-Associated Mutations in Antiretroviral Naïve HIV-1-Infected Latin American Children

    Directory of Open Access Journals (Sweden)

    Luis E. Soto-Ramirez

    2010-01-01

    Full Text Available Our goal was to describe the presence of HIV drug resistance among HIV-1-infected, antiretroviral (ARV naïve children and adolescents in Latin America and to examine resistance in these children in relation to drug exposure in the mother. Genotyping was performed on plasma samples obtained at baseline from HIV-1-infected participants in a prospective cohort study in Brazil, Argentina, and Mexico (NISDI Pediatric Study. Of 713 HIV-infected children enrolled, 69 were ARV naïve and eligible for the analysis. At enrollment, mean age was 7.3 years; 81.2% were infected with HIV perinatally. Drug resistance mutations (DRMs were detected in 6 (8.7%; 95% confidence interval 3.1–18.2% ARV-naïve subjects; none of the mothers of these 6 received ARVs during their pregnancies and none of the children received ARV prophylaxis. Reverse transcriptase mutations K70R and K70E were detected in 3 and 2 subjects, respectively; protease mutation I50 V was detected in 1 subject. Three of the 6 children with DRMs initiated ARV therapy during followup, with a good response in 2. The overall rate of primary drug resistance in this pediatric HIV-infected population was low, and no subjects had more than 1 DRM. Mutations associated with resistance to nucleoside reverse transcriptase inhibitors were the most prevalent.

  14. Resistance and Assent: How Racial Socialization Shapes Black Students' Experience Learning African American History in High School

    Science.gov (United States)

    Thornhill, Theodore E.

    2016-01-01

    African American history is often taught poorly in high school U.S. history courses. However, we know little about how Black students perceive and experience this situation. I use a refined racial socialization framework and interview data with 32 Black college students in the Northeast to investigate how familial racial socialization shapes their…

  15. Cellulomonas xylanilytica sp. nov., a cellulolytic and xylanolytic bacterium isolated from a decayed elm tree.

    Science.gov (United States)

    Rivas, Raúl; Trujillo, Martha E; Mateos, P F; Martínez-Molina, E; Velázquez, Encarna

    2004-03-01

    A Gram-positive, aerobic, non-motile bacterium was isolated from a decayed elm tree. Phylogenetic analysis based on 16S rDNA sequences revealed 99.0 % similarity to Cellulomonas humilata. Chemotaxonomic data that were determined for this isolate included cell-wall composition, fatty acid profiles and polar lipids; the results supported the placement of strain XIL11(T) in the genus Cellulomonas. The DNA G+C content was 73 mol%. The results of DNA-DNA hybridization with C. humilata ATCC 25174(T), in combination with chemotaxonomic and physiological data, demonstrated that isolate XIL11(T) should be classified as a novel Cellulomonas species. The name Cellulomonas xylanilytica sp. nov. is proposed, with strain XIL11(T) (=LMG 21723(T)=CECT 5729(T)) as the type strain.

  16. A Short-Term Photovoltaic Power Prediction Model Based on an FOS-ELM Algorithm

    Directory of Open Access Journals (Sweden)

    Jidong Wang

    2017-04-01

    Full Text Available With the increasing proportion of photovoltaic (PV power in power systems, the problem of its fluctuation and intermittency has become more prominent. To reduce the negative influence of the use of PV power, we propose a short-term PV power prediction model based on the online sequential extreme learning machine with forgetting mechanism (FOS-ELM, which can constantly replace outdated data with new data. We use historical weather data and historical PV power data to predict the PV power in the next period of time. The simulation result shows that this model has the advantages of a short training time and high accuracy. This model can help the power dispatch department schedule generation plans as well as support spatial and temporal compensation and coordinated power control, which is important for the security and stability as well as the optimal operation of power systems.

  17. Dust generation mechanisms under powerful plasma impacts to the tungsten surfaces in ITER ELM simulation experiments

    International Nuclear Information System (INIS)

    Makhlaj, V.A.; Garkusha, I.E.; Aksenov, N.N.; Chuvilo, A.A.; Chebotarev, V.V.; Landman, I.; Malykhin, S.V.; Pestchanyi, S.; Pugachov, A.T.

    2013-01-01

    In recent tokamak simulation experiments with the QSPA Kh-50 facility several mechanisms of dust generation from tungsten surfaces under ITER ELM-like energy loads have been identified. Here cracking and melting are reported. The brittle destruction dominates after a few transient impacts when a network of major cracks forms on the surface. Bifurcation of major cracks results in ejection of dust particles with sizes up to ∼30 μm. Dust generation occurs also after surface melting and following resolidification when fine crack networks along the grain boundaries develop. In this process the destruction is accompanied by bridge formation due to capillary tension across the fine cracks. Next impacts (even weak melt-free ones) can destroy those bridges, which produces considerable amounts of dust particles of nm-size dust. Surface modification after the repetitive plasma pulses also results in creation of nm-size dust

  18. Microsatellite markers for the critically endangered elm species Ulmus gaussenii (Ulmaceae).

    Science.gov (United States)

    Geng, Qi-Fang; Yang, Jie; He, Jia; Wang, Dan-Bi; Shi, En; Xu, Wei-Xiang; Jeelani, Nasreen; Wang, Zhong-Sheng; Liu, Hong

    2016-07-20

    The Anhui elm Ulmus gaussenii is listed as a critically endangered species by the International Union for Conservation of Nature and is endemic to China, where its only population is restricted to Langya Mountain in Chuzhou, Anhui Province. To better understand the population genetics of U. gaussenii, we developed 12 microsatellite markers using an improved technique. The 12 markers were polymorphic, with the number of alleles per locus ranging from two to nine. Observed and expected heterozygosities ranged from 0.021 to 0.750 and 0.225 to 0.744, respectively. The inbreeding coefficient ranged from -0.157 to 0.960. Significant linkage disequilibrium was detected for two pairs of loci, and significant deviations from Hardy-Weinberg equilibrium were found in nine loci. These microsatellite markers will contribute to the studies of population genetics in U. gaussenii, which in turn will contribute to species conservation and protection.

  19. Advertisement Click-Through Rate Prediction Based on the Weighted-ELM and Adaboost Algorithm

    Directory of Open Access Journals (Sweden)

    Sen Zhang

    2017-01-01

    Full Text Available Accurate click-through rate (CTR prediction can not only improve the advertisement company’s reputation and revenue, but also help the advertisers to optimize the advertising performance. There are two main unsolved problems of the CTR prediction: low prediction accuracy due to the imbalanced distribution of the advertising data and the lack of the real-time advertisement bidding implementation. In this paper, we will develop a novel online CTR prediction approach by incorporating the real-time bidding (RTB advertising by the following strategies: user profile system is constructed from the historical data of the RTB advertising to describe the user features, the historical CTR features, the ID features, and the other numerical features. A novel CTR prediction approach is presented to address the imbalanced learning sample distribution by integrating the Weighted-ELM (WELM and the Adaboost algorithm. Compared to the commonly used algorithms, the proposed approach can improve the CTR significantly.

  20. HEART RATE VARIABILITY CLASSIFICATION USING SADE-ELM CLASSIFIER WITH BAT FEATURE SELECTION

    Directory of Open Access Journals (Sweden)

    R Kavitha

    2017-07-01

    Full Text Available The electrical activity of the human heart is measured by the vital bio medical signal called ECG. This electrocardiogram is employed as a crucial source to gather the diagnostic information of a patient’s cardiopathy. The monitoring function of cardiac disease is diagnosed by documenting and handling the electrocardiogram (ECG impulses. In the recent years many research has been done and developing an enhanced method to identify the risk in the patient’s body condition by processing and analysing the ECG signal. This analysis of the signal helps to find the cardiac abnormalities, arrhythmias, and many other heart problems. ECG signal is processed to detect the variability in heart rhythm; heart rate variability is calculated based on the time interval between heart beats. Heart Rate Variability HRV is measured by the variation in the beat to beat interval. The Heart rate Variability (HRV is an essential aspect to diagnose the properties of the heart. Recent development enhances the potential with the aid of non-linear metrics in reference point with feature selection. In this paper, the fundamental elements are taken from the ECG signal for feature selection process where Bat algorithm is employed for feature selection to predict the best feature and presented to the classifier for accurate classification. The popular machine learning algorithm ELM is taken for classification, integrated with evolutionary algorithm named Self- Adaptive Differential Evolution Extreme Learning Machine SADEELM to improve the reliability of classification. It combines Effective Fuzzy Kohonen clustering network (EFKCN to be able to increase the accuracy of the effect for HRV transmission classification. Hence, it is observed that the experiment carried out unveils that the precision is improved by the SADE-ELM method and concurrently optimizes the computation time.

  1. On lateral deflection of the SOL plasma in tokamaks during giant ELMs

    International Nuclear Information System (INIS)

    Landman, I.S.; Wuerz, H.

    2000-06-01

    In recent H-mode experiments at JET with giant ELMs a lateral deflection of hot tokamak plasma leaving the scrape-off layer and striking the divertor plate has been observed. This deflection can effect the divertor erosion caused by the hot plasma irradiation, because of enlarging the irradiated area. A simplified MHD model of the vapor shield plasma and of the hot plasma initially formed at time t → -∞ is analyzed. At t = -∞ both plasmas are assumed to stay on rest and to be separated by a boundary, which is parallel to the plate surface. The interaction between plasmas is assumed to develop gradually ('adiabatically') as exp(t/t 0 ) with t 0 ∝ 10 2 μs the ELM duration time. Electrical insulation of the core tokamak plasma is assumed everywhere except for the contact with the divertor. Electric currents are flowing only in the toroidal direction. These currents developing in the interaction zone of the hot plasma and the rather cold target plasma are calculated for inclined impact of the magnetized hot plasma. At such conditions the J x B force in the lateral direction accelerates the interacting plasmas. The motion of the cold plasma and the gradual increase of the plasma interaction intensity are shown to be important for the appropriate deflection magnitude. Adiabatically responding against the increase of the interaction intensity the cold plasma motion compensates significantly the currents thus decreasing the deflection compared to motionless approach. The calculated magnitude of the hot plasma deflection is comparable to the observed one. The results of the modeling are discussed in relation to the experiments. It is shown that sudden switching on of the interaction produces Alfven oscillations of large amplitudes causing much larger amplitudes of the magnetic field induced by the currents than in the adiabatic case. (orig.)

  2. Experiments on transient melting of tungsten by ELMs in ASDEX Upgrade

    Science.gov (United States)

    Krieger, K.; Balden, M.; Coenen, J. W.; Laggner, F.; Matthews, G. F.; Nille, D.; Rohde, V.; Sieglin, B.; Giannone, L.; Göths, B.; Herrmann, A.; de Marne, P.; Pitts, R. A.; Potzel, S.; Vondracek, P.; ASDEX-Upgrade Team; EUROfusion MST1 Team

    2018-02-01

    Repetitive melting of tungsten by power transients originating from edge localized modes (ELMs) has been studied in ASDEX Upgrade. Tungsten samples were exposed to H-mode discharges at the outer divertor target plate using the divertor manipulator II (DIM-II) system (Herrmann et al 2015 Fusion Eng. Des. 98–9 1496–9). Designed as near replicas of the geometries used also in separate experiments on the JET tokamak (Coenen et al 2015 J. Nucl. Mater. 463 78–84 Coenen et al 2015 Nucl. Fusion 55 023010; Matthews et al 2016 Phys. Scr. T167 7), the samples featured a misaligned leading edge and a sloped ridge respectively. Both structures protrude above the default target plate surface thus receiving an increased fraction of the parallel power flux. Transient melting by ELMs was induced by moving the outer strike point to the sample location. The temporal evolution of the measured current flow from the samples to vessel potential confirmed transient melting. Current magnitude and dependency from surface temperature provided strong evidence for thermionic electron emission as main origin of the replacement current driving the melt motion. The different melt patterns observed after exposures at the two sample geometries support the thermionic electron emission model used in the MEMOS melt motion code, which assumes a strong decrease of the thermionic net current at shallow magnetic field to surface angles (Pitts et al 2017 Nucl. Mater. Energy 12 60–74). Post exposure ex situ analysis of the retrieved samples show recrystallization of tungsten at the exposed surface areas to a depth of up to several mm. The melt layer transport to less exposed surface areas leads to ratcheting pile up of re-solidified debris with zonal growth extending from the already enlarged grains at the surface.

  3. The definition of insulin resistance using HOMA-IR for Americans of Mexican descent using machine learning.

    Science.gov (United States)

    Qu, Hui-Qi; Li, Quan; Rentfro, Anne R; Fisher-Hoch, Susan P; McCormick, Joseph B

    2011-01-01

    The lack of standardized reference range for the homeostasis model assessment-estimated insulin resistance (HOMA-IR) index has limited its clinical application. This study defines the reference range of HOMA-IR index in an adult Hispanic population based with machine learning methods. This study investigated a Hispanic population of 1854 adults, randomly selected on the basis of 2000 Census tract data in the city of Brownsville, Cameron County. Machine learning methods, support vector machine (SVM) and Bayesian Logistic Regression (BLR), were used to automatically identify measureable variables using standardized values that correlate with HOMA-IR; K-means clustering was then used to classify the individuals by insulin resistance. Our study showed that the best cutoff of HOMA-IR for identifying those with insulin resistance is 3.80. There are 39.1% individuals in this Hispanic population with HOMA-IR>3.80. Our results are dramatically different using the popular clinical cutoff of 2.60. The high sensitivity and specificity of HOMA-IR>3.80 for insulin resistance provide a critical fundamental for our further efforts to improve the public health of this Hispanic population.

  4. The definition of insulin resistance using HOMA-IR for Americans of Mexican descent using machine learning.

    Directory of Open Access Journals (Sweden)

    Hui-Qi Qu

    Full Text Available The lack of standardized reference range for the homeostasis model assessment-estimated insulin resistance (HOMA-IR index has limited its clinical application. This study defines the reference range of HOMA-IR index in an adult Hispanic population based with machine learning methods.This study investigated a Hispanic population of 1854 adults, randomly selected on the basis of 2000 Census tract data in the city of Brownsville, Cameron County. Machine learning methods, support vector machine (SVM and Bayesian Logistic Regression (BLR, were used to automatically identify measureable variables using standardized values that correlate with HOMA-IR; K-means clustering was then used to classify the individuals by insulin resistance.Our study showed that the best cutoff of HOMA-IR for identifying those with insulin resistance is 3.80. There are 39.1% individuals in this Hispanic population with HOMA-IR>3.80.Our results are dramatically different using the popular clinical cutoff of 2.60. The high sensitivity and specificity of HOMA-IR>3.80 for insulin resistance provide a critical fundamental for our further efforts to improve the public health of this Hispanic population.

  5. Multilocus sequence typing, biochemical and antibiotic resistance characterizations reveal diversity of North American strains of the honey bee pathogen Paenibacillus larvae.

    Directory of Open Access Journals (Sweden)

    Sasiprapa Krongdang

    Full Text Available Paenibacillus larvae is a Gram positive bacterium and the causative agent of the most widespread fatal brood disease of honey bees, American foulbrood (AFB. A total of thirty-three independent Paenibacillus larvae isolates from various geographical origins in North America and five reference strains were investigated for genetic diversity using multilocus sequence typing (MLST. This technique is regarded to be a powerful tool for epidemiological studies of pathogenic bacteria and is widely used in genotyping assays. For MLST, seven housekeeping gene loci, ilvD (dihydroxy-acid dyhydrogenase, tri (triosephosphate isomerase, purH (phospharibosyl-aminoimidazolecarboxamide, recF (DNA replication and repair protein, pyrE (orotate phosphoribosyltransferase, sucC (succinyl coenzyme A synthetase β subunit and glpF (glycerol uptake facilitator protein were studied and applied for primer designs. Previously, ERIC type DNA fingerprinting was applied to these same isolates and the data showed that almost all represented the ERIC I type, whereas using BOX-PCR gave an indication of more diversity. All isolates were screened for resistance to four antibiotics used by U.S. beekeepers, showing extensive resistance to tetracycline and the first records of resistance to tylosin and lincomycin. Our data highlight the intraspecies relationships of P. larvae and the potential application of MLST methods in enhancing our understanding of epidemiological relationships among bacterial isolates of different origins.

  6. Explaining the Effects of Narrative in an Entertainment Television Program: Overcoming Resistance to Persuasion

    Science.gov (United States)

    Moyer-Guse, Emily; Nabi, Robin L.

    2010-01-01

    Research has examined the ability of entertainment-education (E-E) programs to influence behavior across a variety of health and social issues. However, less is known about the underlying mechanisms that account for these effects. In keeping with the extended elaboration likelihood model (E-ELM) and the entertainment overcoming resistance model…

  7. Beta-lactam resistance mechanisms in Pseudomonas aeruginosa strains causing bloodstream infections: comparative results between Brazilian and American isolates.

    Science.gov (United States)

    Fehlberg, Lorena C C; Xavier, Danilo E; Peraro, Paula P; Marra, Alexandre R; Edmond, Michael B; Gales, Ana C

    2012-08-01

    This study evaluated the presence of distinct mechanisms of beta-lactam resistance in 122 Pseudomonas aeruginosa isolates, causing bloodstream infections at Hospital São Paulo (HSP, Brazil; 82 isolates) and Virginia Commonwealth University Medical Center (VCU, United States; 40 isolates). By Clinical Laboratory Standards Institute agar dilution, Brazilian P. aeruginosa isolates showed higher resistance rates to most antimicrobials tested than those collected from the United States, except for ciprofloxacin. Carbapenem hydrolysis was detected in seven P. aeruginosa from HSP, in which bla(SPM-1) (n=5), bla(IMP-1) (n=1), and bla(IMP-16) (n=1) were detected by polymerase chain reaction (PCR) followed by DNA sequencing. The production of GES-5 was observed in 1.25% of HSP isolates. No extended-spectrum beta-lactamase-encoding genes were detected in the VCU isolates. Expression of efflux systems genes (mexB, mexD, mexF, and mexY) was evaluated by quantitative reverse transcriptase-PCR. In HSP isolates MexXY-OprM (41.4%) efflux system was more frequently overexpressed, in contrast to what was observed in the VCU isolates, where both MexXY-OprM (25.0%) and MexAB-OprM (25.0%) were equally overexpressed. The oprD downregulation was similar among isolates collected from the HSP (92.7%) and VCU (95.0%). On the other hand, ampC overexpression was observed only among HSP isolates (31.7%). The distinct antimicrobial susceptibility profile and mechanisms of beta-lactam resistance found among P. aeruginosa isolated from teaching hospitals located in Brazil and the United States exemplify the importance of local epidemiology in determining antimicrobial resistance rates.

  8. Variability of morphometric caracteristics of one-year seedlings of different half-sib European White Elm (Ulmus effusa Wild. from the Great War Island

    Directory of Open Access Journals (Sweden)

    Devetaković, J.

    2013-12-01

    Full Text Available European White Elm is recognized as a rare and endangered species in the forest fund of the Republic of Serbia. During the past century massive drying of elms occurred and the indications of their extinction appeared, which consequently led to a reduction in genetic diversity and the danger of genetic drift. In the area of the Great War Island near Belgrade we found 56 trees of European White Elm that are spatially divided into three subpopulations. In order to assess the genetic potential of European White Elm in the Great War Island and to define adequate conservation measures variability of 14 selected test trees progeny was rated. Results shows that the satisfactory variability within the popoulation exists, which is a good basis for the conservation of genepool available.

  9. 78 FR 21345 - In the Matter of: Liem Duc Huynh, a/k/a Duc Huynh, 2905 South Elm, Broken Arrow, OK 74012; Order...

    Science.gov (United States)

    2013-04-10

    ... Arrow, OK 74012; Order Denying Export Privileges On April 17, 2012, in the U.S. District Court, Central... last known address at: 2905 South Elm, Broken Arrow, OK 74012, and when acting for or on behalf of...

  10. Resistência à traça-do-tomateiro em plantas com altos teores de acilaçúcares nas folhas Resistance to the South American tomato pinworm in tomato plants with high foliar acylsugar contents

    Directory of Open Access Journals (Sweden)

    Álvaro C Gonçalves Neto

    2010-06-01

    Full Text Available A traça-do-tomateiro foi constatada pela primeira vez no Brasil em 1980 estando hoje dentre as principais pragas da tomaticultura nacional. O controle desta praga é feito principalmente por inseticidas, sendo realizada em casos extremos, até três pulverizações semanais. Acessos silvestres de tomateiro como S. pennellii LA-716 possuem resistência a pragas, mediada pela presença de acilaçúcares nos folíolos. Os objetivos deste trabalho foram obter genótipos de tomateiro com características comerciais e altos teores foliares de acilaçúcares (AA, e avaliar seus níveis de resistência à traça do tomateiro Tuta absoluta. Os genótipos foram obtidos a partir de populações segregantes (F2 oriundas do cruzamento entre AF-8665 (linhagem elite com baixos teores de AA e as linhagens BPX370E-30-275-11-7, BPX370E-30-275-11-8, BPX370E-30-380-68-6 e BPX370E-30-380-68-8 (linhagens pré-comerciais com altos teores, obtidas a partir do cruzamento interespecífico S. lycopersicum x S. pennellii LA-716. Plantas F2 previamente selecionadas com base nos teores de AA foram clonadas e em seguida testadas quanto à resistência à traça-do-tomateiro. Genótipos selecionados para altos teores de AA expressaram menor ovoposição da traça e níveis inferiores de danos causados à planta pela infestação do microlepidóptero do que genótipos (comerciais ou não com baixos teores de AA. Embora genótipos com altos teores de AA tenham sido mais resistentes à traça do que os demais, seus níveis de resistência podem ser dependentes do background genotípico: clones BPX-410H (alto teor de AA mostraram-se em geral ligeiramente mais resistentes do que o dos clones BPX-370G (também alto teor de AA. Os clones BPX-410H-01pl#281, BPX-410H-04pl#348 e BPX-410H-04pl#481 foram superiores nas avaliações de resistência à traça e são recomendados para a continuidade do programa de melhoramento.The South American tomato pinworm was first detected in Brazil

  11. Estimation of the dust production rate from the tungsten armour after repetitive ELM-like heat loads

    Science.gov (United States)

    Pestchanyi, S.; Garkusha, I.; Makhlaj, V.; Landman, I.

    2011-12-01

    Experimental simulations for the erosion rate of tungsten targets under ITER edge-localized mode (ELM)-like surface heat loads of 0.75 MJ m-2 causing surface melting and of 0.45 MJ m-2 without melting have been performed in the QSPA-Kh50 plasma accelerator. Analytical considerations allow us to conclude that for both energy deposition values the erosion mechanism is solid dust ejection during surface cracking under the action of thermo-stress. Tungsten influx into the ITER containment of NW~5×1018 W per medium size ELM of 0.75 MJ m-2 and 0.25 ms time duration has been estimated. The radiation cooling power of Prad=150-300 MW due to such influx of tungsten is intolerable: it should cool the ITER core to 1 keV within a few seconds.

  12. Estimation of the dust production rate from the tungsten armour after repetitive ELM-like heat loads

    International Nuclear Information System (INIS)

    Pestchanyi, S; Landman, I; Garkusha, I; Makhlaj, V

    2011-01-01

    Experimental simulations for the erosion rate of tungsten targets under ITER edge-localized mode (ELM)-like surface heat loads of 0.75 MJ m - 2 causing surface melting and of 0.45 MJ m - 2 without melting have been performed in the QSPA-Kh50 plasma accelerator. Analytical considerations allow us to conclude that for both energy deposition values the erosion mechanism is solid dust ejection during surface cracking under the action of thermo-stress. Tungsten influx into the ITER containment of N W ∼5×10 18 W per medium size ELM of 0.75 MJ m - 2 and 0.25 ms time duration has been estimated. The radiation cooling power of P rad =150-300 MW due to such influx of tungsten is intolerable: it should cool the ITER core to 1 keV within a few seconds.

  13. Effect of stationary high heat flux and transient ELMs-like heat loads on the divertor PFCs

    Energy Technology Data Exchange (ETDEWEB)

    Riccardi, B., E-mail: bruno.riccardi@f4e.europa.eu [Fusion for Energy, ITER Department, Josep Pla, 2, Torres Diagonal Litoral B3, 08019 Barcelona (Spain); Gavila, P. [Fusion for Energy, ITER Department, Josep Pla, 2, Torres Diagonal Litoral B3, 08019 Barcelona (Spain); Giniatulin, R. [Efremov Institute, 196641 St. Petersburg (Russian Federation); Kuznetsov, V. [SRC RF TRINITI, ul. Pushkovykh, vladenie 12, 142190 Troitsk, Moscow Region (Russian Federation); Rulev, R. [Efremov Institute, 196641 St. Petersburg (Russian Federation); Klimov, N.; Kovalenko, D.; Barsuk, V. [SRC RF TRINITI, ul. Pushkovykh, vladenie 12, 142190 Troitsk, Moscow Region (Russian Federation); Koidan, V.; Korshunov, S. [NRC “Kurchatov Institute”, Moscow (Russian Federation)

    2013-10-15

    The experimental evaluation of the divertor plasma facing components (PFCs) lifetime under transient events, such as edge localized modes (ELMs) and high heat flux (HHF) thermal fatigue expected during ITER normal operations and slow transient events is here presented. The experiments have been performed in the frame of an EU/RF collaboration. For carbon fiber composite material the erosion is caused by PAN fiber damage whilst the erosion of tungsten is determined by the melt layer movement and crack formation. The conclusion of this study is that, in addition to the structural change produced in the armor materials by ELMs-like loads, some mock ups showed also a degradation of the thermal fatigue performances.

  14. Resistance among Gram-negative ESKAPE pathogens isolated from hospitalized patients with intra-abdominal and urinary tract infections in Latin American countries: SMART 2013–2015

    Directory of Open Access Journals (Sweden)

    James A. Karlowsky

    2017-05-01

    Full Text Available Gram-negative ESKAPE pathogens (Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species are important etiologic agents of nosocomial infection that are frequently resistant to broad-spectrum antimicrobial agents. Gram-negative ESKAPE pathogens were collected from hospitalized patients in 11 Latin American countries from 2013 to 2015 as part of the Study for Monitoring Antimicrobial Resistance Trends (SMART global surveillance program. In total, 2113 isolates from intra-abdominal infections (IAI and 970 isolates from urinary tract infections (UTI were tested against antimicrobial agents using standardized CLSI broth microdilution methodology. Of the agents tested, amikacin demonstrated the highest rates of susceptibility (% for K. pneumoniae (92.2, 92.3, Enterobacter spp. (97.5, 92.1, and P. aeruginosa (85.3, 75.2 isolates from both IAI and UTI, respectively. Ertapenem (68.5, 62.6 and imipenem (79.2, 75.9 showed substantially higher rates of susceptibility (% than other β-lactams, including piperacillin-tazobactam (35.9, 37.4 against ESBL-positive isolates of K. pneumoniae from IAI and UTI, respectively. Rates of susceptibility to all agents tested against A. baumannii were ≤30.9%. Gram-negative ESKAPE pathogens isolated from Latin America demonstrated compromised in vitro susceptibility to commonly prescribed broad-spectrum, parenteral antimicrobial agents. Continued surveillance is warranted. New antimicrobial agents with potent activity against Gram-negative ESKAPE pathogens are urgently needed.

  15. Comparison of SVM, RF and ELM on an Electronic Nose for the Intelligent Evaluation of Paraffin Samples

    Directory of Open Access Journals (Sweden)

    Hong Men

    2018-01-01

    Full Text Available Paraffin odor intensity is an important quality indicator when a paraffin inspection is performed. Currently, paraffin odor level assessment is mainly dependent on an artificial sensory evaluation. In this paper, we developed a paraffin odor analysis system to classify and grade four kinds of paraffin samples. The original feature set was optimized using Principal Component Analysis (PCA and Partial Least Squares (PLS. Support Vector Machine (SVM, Random Forest (RF, and Extreme Learning Machine (ELM were applied to three different feature data sets for classification and level assessment of paraffin. For classification, the model based on SVM, with an accuracy rate of 100%, was superior to that based on RF, with an accuracy rate of 98.33–100%, and ELM, with an accuracy rate of 98.01–100%. For level assessment, the R2 related to the training set was above 0.97 and the R2 related to the test set was above 0.87. Through comprehensive comparison, the generalization of the model based on ELM was superior to those based on SVM and RF. The scoring errors for the three models were 0.0016–0.3494, lower than the error of 0.5–1.0 measured by industry standard experts, meaning these methods have a higher prediction accuracy for scoring paraffin level.

  16. Bud dormancy release in elm (Ulmus spp.) clones--a case study of photoperiod and temperature responses.

    Science.gov (United States)

    Ghelardini, Luisa; Santini, Alberto; Black-Samuelsson, Sanna; Myking, Tor; Falusi, Mauro

    2010-02-01

    Dormancy release as influenced by duration of outdoor winter chilling in Florence (Italy) was studied under different photoperiodic and temperature treatments in collected twigs of two European (Ulmus glabra Huds. and Ulmus minor Mill.) and four Asian (Ulmus pumila L., Ulmus parvifolia Jacq., Ulmus macrocarpa Hance and Ulmus villosa Brandis) elm clones. Photoperiod had no effect on dormancy release, and there was no evidence that photoperiod affected bud burst during quiescence in the studied elm clones. Thermal time (day degrees >0 degrees C) to bud burst decreased in all the clones with increasing outdoor chilling. Although all the clones exhibited a rather weak dormancy, they significantly differed from each other. Dormancy was released earlier in the Asian than in the European clones, and the clones could be ranked from the U. pumila clone (very weak and short dormancy) to the U. minor clone (relatively stronger and longer dormancy), the other clones being intermediate. In all the clones except U. minor, the observed decrement in thermal time to bud burst was efficiently explained as an inverse exponential function of the number of chill days < or =5 degrees C received outdoor in autumn and winter. Endodormancy, as measured by the single-node cuttings test, was weak and short in all the clones. The latter result suggests that correlative inhibitions were largely responsible for preventing bud burst during winter in these elm clones.

  17. Experimental and numerical simulations of ELM-like transient damage behaviors to different grade tungsten and tungsten alloys

    International Nuclear Information System (INIS)

    Liu, Xiang; Lian, Youyun; Chen, Lei; Chen, Zhenkui; Chen, Jiming; Duan, Xuru; Fan, Jinlian; Song, Jiupeng

    2015-01-01

    Transient heat loads, such as plasma disruptions and ELMs, could induce plastic deformations, cracking, melting, even fatigue cracks and creep of tungsten (W) surface. A high purity W, CVD-W coating, TiC dispersion strengthened and K doped tungsten alloys were tested in a 60 kW electron-beam facility by simulating the transient load events under different base temperatures. It was found that CVD-W, W-TiC and W-K alloys have higher crack thresholds than high purity W, meanwhile CVD-W is more sensitive to the crack disappearing at elevated base temperatures. On the other hand, repetitive pulse loading like ELMs can induce serious network cracks even the power density was quite lower than the crack threshold determined by a single shot. The ABAQUS code was used to simulate the crack behaviors of ITER grade pure W by a single shot and a FE-SAFE code was adopted to estimate the fatigue life under ELMs-like loads. A good agreement with experiment results was found

  18. New Small-ELM H-mode Regimes for Steady-state High-performance Operations in EAST

    Science.gov (United States)

    Xu, G. S.; Yang, Q. Q.; Wang, Y. F.; Yan, N.; Hu, G. H.; Lin, X.; Xu, X. Q.; Garofalo, A. M.; Maingi, R.; EAST Team

    2017-10-01

    A stationary high-confinement (H98y2 1.1) fully non-inductive H-mode regime characterized by high-frequency (2kHz) small ELMs (divertor peak heat flux 2MW/m2) at relatively low pedestal collisionality (ν*e 1) and optimized high internal inductance (li 1.1) plasma has been recently achieved with high heating power (source power 9MW) in EAST. This regime was obtained at high triangularity δ (0.55), high q95 (6) and high βp (1.6), close to the parameter space of the grassy ELM regime in JT-60U. The relatively low plasma current, high q95, βp, and therefore high bootstrap current fraction (>30%) make it a suitable regime to achieve steady-state operation with low disruptivity, good reproducibility and robustness. The access to this regime is insensitive to the change of toroidal torque or plasma density in the explored parameter range. Benefiting from the optimized high li and high βp, good core energy confinement has been achieved even at low core toroidal rotation (Vt down to 10 km/s). Good density control has been achieved at a line-averaged density up to 76% Greenwald. Impurity concentration and core radiation were maintained at an acceptably low level, suggesting that sufficient particle exhaust can be driven by the high-frequency small ELMs.

  19. Obesity and Insulin Resistance Screening Tools in American Adolescents: National Health and Nutrition Examination Survey (NHANES) 1999 to 2010.

    Science.gov (United States)

    Lee, Joey A; Laurson, Kelly R

    2016-08-01

    To identify which feasible obesity and insulin resistance (IR) screening tools are most strongly associated in adolescents by using a nationally representative sample. Adolescents aged 12.0 to 18.9 years who were participating in the National Health and Nutrition Examination Survey (NHANES) (n=3584) and who were measured for height, weight, waist circumference (WC), triceps and subscapular skinfold thickness, glycated hemoglobin, fasting glucose (FG) and fasting insulin (FI) level were included. Adolescents were split by gender and grouped by body mass index (BMI) percentile. Age- and gender-specific classifications were constructed for each obesity screening tool measure to account for growth and maturation. General linear models were used to establish groups objectively for analysis based on when IR began to increase. Additional general linear models were used to identify when IR significantly increased for each IR measure as obesity group increased and to identify the variance accounted for among each obesity-IR screening tool relationship. As the obesity group increased, homeostasis model assessment-insulin resistance (HOMA-IR) and FI significantly increased, while FG increased only (above the referent) in groups with BMI percentiles ≥95.0, and glycated hemoglobin level did not vary across obesity groups. The most strongly associated screening tools were WC and FI in boys (R(2)=0.253) and girls (R(2)=0.257). FI had the strongest association with all of the obesity measures. BMI associations were slightly weaker than WC in each in relation to IR. Our findings show that WC and FI are the most strongly associated obesity and IR screening tool measures in adolescents. These feasible screening tools should be utilized in screening practices for at-risk adolescents. Copyright © 2015 Canadian Diabetes Association. Published by Elsevier Inc. All rights reserved.

  20. VizieR Online Data Catalog: Subdwarf A stars vs ELM WDs radial velocities (Brown+, 2017)

    Science.gov (United States)

    Brown, W. R.; Kilic, M.; Gianninas, A.

    2017-11-01

    Our sample is comprised of 11 subdwarf A-type (sdA) stars suspected of being eclipsing binaries (S. O. Kepler 2015, private communication) and 11 previously unpublished extremely low mass (ELM) white dwarf (WD) candidates that have sdA-like temperatures summarized in Table 1. We obtain time-series spectroscopy for all 22 objects and time-series optical photometry for 21 objects. We also obtain JHK infrared photometry for 6 objects. We obtain time-series spectroscopy for 20 of the 22 objects with the 6.5m MMT telescope. We obtain spectra for the two brightest objects with the 1.5m Tillinghast telescope at Fred Lawrence Whipple Observatory. We obtain additional spectra for six objects with the 4m Mayall telescope at Kitt Peak National Observatory. The spectra were mostly acquired in observing runs between 2014 December and 2016 December. We search the Catalina Surveys Data Release 2 (Drake+ 2009, J/ApJ/696/870) and find time-series V-band photometry for 21 of the 22 objects. Six objects show significant eclipses. (3 data files).

  1. [Effect of lactic acid bacteria isolated from Tibetan Plateau on silage fermentation quality of Elms nutans].

    Science.gov (United States)

    Zhang, Hongmei; Ke, Wencan; Jing, Peixin; Zhang, Juan; Chen, Ming; Yu, Yingwen; Guo, Xusheng

    2015-10-04

    In order to detect the effect of lactic acid bacteria isolated from Tibetan Plateau on silage fermentation quality of Elms nutans. We used 3 isolated lactic acid bacteria with better growth at low temperatures of 10 and 15 degrees C at ensiling of Elymus nutans. Subsequently, effects of the selected lactic acid bacteria on fermentation profiles of Elymus nutans silages stored at 15 and 25 degrees C were evaluated by using the same species of commercial inoculants as the control. PP-6 isolated from Tibetan Plateau could ferment raffinose, lactose, sorbitol, melibiose and sucrose, and LS-5 could ferment cottonseed sugar, laetrile, rhamnose, lactose, sorbitol, xylose, arabinose, melibiose and sucrose, but the same species of commercial strains could not use these sugars. Inoculation of these three strains into Elymus nutans at 15 and 25 degrees C ensiled for 50 d, we found that LS-5 significantly reduced silage pH, propionic acid concentration and ratio of ammonia nitrogen/total nitrogen at 15 degrees C (P lactic acid concentration (P < 0.05), resulting in a lower ratio of ammonia nitrogen/total nitrogen, saved more crude protein and significantly reduced neutral detergent fiber content (P < 0.05) as compared with the commercial strains. The three isolated strains can improve silage quality of Elymus nutans growing on the Qinghai-Tibetan Plateau at low temperature, but these strains have no obvious advantages at 25 degrees C in comparison with the commercial inoculants.

  2. Stem Weight Ratios of Siberian Elm (Ulmus Pumila L.) Grown as a Short Rotation Crop

    Energy Technology Data Exchange (ETDEWEB)

    Iriarte, Leyre; Fernandez, Jesus [Univ. Politecnica de Madrid (Spain). Dept. de Produccion Vegetal

    2006-07-15

    Siberian elm (Ulmus pumila L.) is a fast growing tree which has not been studied extensively for short rotation crop (SRC) purposes. Seedlings were planted in Madrid (Spain) in the year 2000 at a density of 1 plant/m{sup 2}. Trials were carried out in order to evaluate the biomass production in high-density plantations. The plantation was cut after the fourth growing season and evaluated for height, diameter, and dry weight. The same measurements were repeated for the sprouts of the 1st and 2nd year that followed. The mean biomass yield after 4 years was 101.6 g dw/m{sup 2} year-1; 269 g dw /m{sup 2} for 1-year-old sprouts and 480.4 g dw /m{sup 2} for 2-year-old sprouts. Correlations between height and basal diameter with dry weight were calculated for each year. There was a close correlation between the 4th year original plant weight and the 1-year-old sprouts but less than with the 2nd year. Water efficiency for biomass production was higher during the 2nd sprouting cycle.

  3. A Novel Multimodal Biometrics Recognition Model Based on Stacked ELM and CCA Methods

    Directory of Open Access Journals (Sweden)

    Jucheng Yang

    2018-04-01

    Full Text Available Multimodal biometrics combine a variety of biological features to have a significant impact on identification performance, which is a newly developed trend in biometrics identification technology. This study proposes a novel multimodal biometrics recognition model based on the stacked extreme learning machines (ELMs and canonical correlation analysis (CCA methods. The model, which has a symmetric structure, is found to have high potential for multimodal biometrics. The model works as follows. First, it learns the hidden-layer representation of biological images using extreme learning machines layer by layer. Second, the canonical correlation analysis method is applied to map the representation to a feature space, which is used to reconstruct the multimodal image feature representation. Third, the reconstructed features are used as the input of a classifier for supervised training and output. To verify the validity and efficiency of the method, we adopt it for new hybrid datasets obtained from typical face image datasets and finger-vein image datasets. Our experimental results demonstrate that our model performs better than traditional methods.

  4. A genome-wide association study of field and seedling response to stem rust pathogen races reveals combinations of race-specific resistance genes in North American spring wheat

    Science.gov (United States)

    Stem rust of wheat caused by the fungal pathogen Puccinia graminis f. sp. tritici historically caused major yield losses of wheat worldwide. To understand the genetic basis of stem rust resistance in conventional North American spring wheat, genome-wide association analysis (GWAS) was conducted on a...

  5. Systemic therapy in men with metastatic castration-resistant prostate cancer:American Society of Clinical Oncology and Cancer Care Ontario clinical practice guideline.

    Science.gov (United States)

    Basch, Ethan; Loblaw, D Andrew; Oliver, Thomas K; Carducci, Michael; Chen, Ronald C; Frame, James N; Garrels, Kristina; Hotte, Sebastien; Kattan, Michael W; Raghavan, Derek; Saad, Fred; Taplin, Mary-Ellen; Walker-Dilks, Cindy; Williams, James; Winquist, Eric; Bennett, Charles L; Wootton, Ted; Rumble, R Bryan; Dusetzina, Stacie B; Virgo, Katherine S

    2014-10-20

    To provide treatment recommendations for men with metastatic castration-resistant prostate cancer (CRPC). The American Society of Clinical Oncology and Cancer Care Ontario convened an expert panel to develop evidence-based recommendations informed by a systematic review of the literature. When added to androgen deprivation, therapies demonstrating improved survival, improved quality of life (QOL), and favorable benefit-harm balance include abiraterone acetate/prednisone, enzalutamide, and radium-223 ((223)Ra; for men with predominantly bone metastases). Improved survival and QOL with moderate toxicity risk are associated with docetaxel/prednisone. For asymptomatic/minimally symptomatic men, improved survival with unclear QOL impact and low toxicity are associated with sipuleucel-T. For men who previously received docetaxel, improved survival, unclear QOL impact, and moderate to high toxicity risk are associated with cabazitaxel/prednisone. Modest QOL benefit (without survival benefit) and high toxicity risk are associated with mitoxantrone/prednisone after docetaxel. No benefit and excess toxicity are observed with bevacizumab, estramustine, and sunitinib. Continue androgen deprivation (pharmaceutical or surgical) indefinitely. Abiraterone acetate/prednisone, enzalutamide, or (223)Ra should be offered; docetaxel/prednisone should also be offered, accompanied by discussion of toxicity risk. Sipuleucel-T may be offered to asymptomatic/minimally symptomatic men. For men who have experienced progression with docetaxel, cabazitaxel may be offered, accompanied by discussion of toxicity risk. Mitoxantrone may be offered, accompanied by discussion of limited clinical benefit and toxicity risk. Ketoconazole or antiandrogens (eg, bicalutamide, flutamide, nilutamide) may be offered, accompanied by discussion of limited known clinical benefit. Bevacizumab, estramustine, and sunitinib should not be offered. There is insufficient evidence to evaluate optimal sequences or

  6. Edge stability and performance of the ELM-free quiescent H-mode and the quiescent double barrier mode on DIII-D

    International Nuclear Information System (INIS)

    West, W.P.; Burrell, K.H.; Snyder, P.B.; Gohil, P.; Lao, L.L.; Leonard, A.W.; Osborne, T.H.; Thomas, D.M.; Casper, T.A.; Lasnier, C.J.; Doyle, E.J.; Wang, G.; Zeng, L.; Nave, M.F.F.

    2005-01-01

    The quiescent H (QH) mode, an edge localized mode (ELM)-free, high-confinement mode, combines well with an internal transport barrier to form quiescent double barrier (QDB) stationary state, high performance plasmas. The QH-mode edge pedestal pressure is similar to that seen in ELMing phases of the same discharge, with similar global energy confinement. The pedestal density in early ELMing phases of strongly pumped counter injection discharges drops and a transition to QH-mode occurs, leading to lower calculated edge bootstrap current. Plasmas current ramp experiment and ELITE code modeling of edge stability suggest that QHmodes lie near an edge current stabilty boundary. At high triangularity, QH-mode discharges operate at higher pedestal density and pressure, and have achieved ITER level values of β PED and ν*. The QDB achieves performance of β N H 89 ∼ 7 in quasi-stationary conditions for a duration of 10 τ E , limited by hardware. Recently we demonstrated stationary state QDB discharges with little change in kinetic and q profiles (q 0 > 1) for 2 s, comparable to ELMing 'hybrid scenarios', yet without the debilitating effects of ELMs. Plasma profile control tools, including electron cyclotron heating and current drive and neutral beam heating, have been demonstrated to control simultaneously the q profile development, the density peaking, impurity accumulation and plasma beta. (author)

  7. Material Surface Damage under High Pulse Loads Typical for ELM Bursts and Disruptions in ITER

    Science.gov (United States)

    Landman, I. S.; Pestchanyi, S. E.; Safronov, V. M.; Bazylev, B. N.; Garkusha, I. E.

    The divertor armour material for the tokamak ITER will probably be carbon manufactured as fibre composites (CFC) and tungsten as either brush-like structures or thin plates. Disruptive pulse loads where the heat deposition Q may reach 102 MJ/m 2 on a time scale Ïä of 3 ms, or operation in the ELMy H-mode at repetitive loads with Q âe 1/4 3 MJ/m2 and Ïä âe 1/4 0.3 ms, deteriorate armour performance. This work surveys recent numerical and experimental investigations of erosion mechanisms at these off-normal regimes carried out at FZK, TRINITI, and IPP-Kharkov. The modelling uses the anisotropic thermomechanics code PEGASUS-3D for the simulation of CFC brittle destruction, the surface melt motion code MEMOS-1.5D for tungsten targets, and the radiation-magnetohydrodynamics code FOREV-2D for calculating the plasma impact and simulating the heat loads for the ITER regime. Experiments aimed at validating these codes are being carried out at the plasma gun facilities MK-200UG, QSPA-T, and QSPA-Kh50 which produce powerful streams of hydrogen plasma with Q = 10–30 MJ/m2 and Ïä = 0.03–0.5 ms. Essential results are, for CFC targets, the experiments at high heat loads and the development of a local overheating model incorporated in PEGASUS-3D, and for the tungsten targets the analysis of evaporation- and melt motion erosion on the base of MEMOS-1.5D calculations for repetitive ELMs.

  8. The dissection and SSR mapping of a high-temperature adult-plant stripe rust resistance gene in American spring wheat cultivar Alturas

    Science.gov (United States)

    Stripe rust is one of major diseases in wheat production worldwide. The best economic and efficient method is to utilize resistant varieties. Alturas has high-temperature adult-plant resistance. In order to determine stripe rust resistance characteristics, resistance gene combination and molecular m...

  9. Effect of misaligned edges and magnetic field orientation on plasma deposition into gaps during ELMs on ITER

    Czech Academy of Sciences Publication Activity Database

    Dejarnac, Renaud; Komm, Michael; Gunn, J. P.; Pekarek, Z.

    2011-01-01

    Roč. 415, č. 1 (2011), S977-S980 ISSN 0022-3115. [International Conference on Plasma-Surface Interactions in Controlled Fusion (PSI19)/19th./. San Diego, 24.05.2010-28.05.2010] Institutional research plan: CEZ:AV0Z20430508 Keywords : Edge modeling * Plasma-wall interactions * ITER * Sheaths * ELMs Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 2.052, year: 2011 http://www.sciencedirect.com/science/article/pii/S0022311510005520

  10. Balance of the stored energies sustained by the internal and edge transport barriers and effects of ELMs and L-H transitions in JT-60U

    International Nuclear Information System (INIS)

    Kamada, Y.; Yoshida, M.; Sakamoto, Y.; Koide, Y.; Oyama, N.; Urano, H.; Kamiya, K.; Suzuki, T.; Isayama, A.

    2009-01-01

    To understand key physics processes determining radial profiles of the kinetic plasma parameters in the advanced tokamak operation scenarios, correlations between the edge transport barrier (ETB) and the internal transport barrier (ITB) have been studied in the JT-60U tokamak device. It has been found that the edge pedestal poloidal beta, β p -ped, increases almost linearly with the total poloidal beta, β p -tot, over a wide range of the plasma current for type I ELMing H-mode plasmas, and this dependence becomes stronger with increasing triangularity. This dependence is not due to the profile stiffness, since the dependence is the same regardless of the existence of ITB. As the stored energy inside the ITB-foot radius (W ITB ) increases, the total thermal stored energy (W th ) increases and then the pedestal stored energy (W ped ) increases. On the other hand, as W ped increases, the ELM penetration expands more inwards and finally reaches the ITB-foot radius. At this situation, the ITB-foot radius cannot move outwards because of the erosion by ELMs. Then the fractions of W ITB /W th and W ped /W th become almost constant. It has also been found that the type I ELM expels/decreases the edge toroidal momentum larger than the edge ion thermal energy. The ELM penetration for the toroidal rotation tends to be deeper than that for the ion temperature and can exceed the ITB-foot radius. The ELM penetration is deeper for CO-rotating plasmas than CTR rotating plasmas. In both cases, the ELM penetration is deeper in the order of the toroidal rotation (V t ), the ion temperature (T i ) and then the electron temperature (T e ). The L-H transition also changes the V t profile more significantly than the T i profile. At the L-H transition, the pedestal V t shifts into the CTR-direction deeply and suddenly without a change in T i , and then the pedestal V t grows further together with a growth of the pedestal T i in a slower timescale. Such changes in V t by ELMs and L

  11. Phenological responses of Ulmus pumila (Siberian Elm) to climate change in the temperate zone of China

    Science.gov (United States)

    Chen, Xiaoqiu; Xu, Lin

    2012-07-01

    Using Ulmus pumila (Siberian Elm) leaf unfolding and leaf fall phenological data from 46 stations in the temperate zone of China for the period 1986-2005, we detected linear trends in both start and end dates and length of the growing season. Moreover, we defined the optimum length period during which daily mean temperature affects the growing season start and end dates most markedly at each station in order to more precisely and rationally identify responses of the growing season to temperature. On average, the growing season start date advanced significantly at a rate of -4.0 days per decade, whereas the growing season end date was delayed significantly at a rate of 2.2 days per decade and the growing season length was prolonged significantly at a rate of 6.5 days per decade across the temperate zone of China. Thus, the growing season extension was induced mainly by the advancement of the start date. At individual stations, linear trends of the start date correlate negatively with linear trends of spring temperature during the optimum length period, namely, the quicker the spring temperature increased at a station, the quicker the start date advanced. With respect to growing season response to interannual temperature variation, a 1°C increase in spring temperature during the optimum length period may induce an advancement of 2.8 days in the start date of the growing season, whereas a 1°C increase in autumn temperature during the optimum length period may cause a delay of 2.1 days in the end date of the growing season, and a 1°C increase in annual mean temperature may result in a lengthening of the growing season of 9 days across the temperate zone of China. Therefore, the response of the start date to temperature is more sensitive than the response of the end date. At individual stations, the sensitivity of growing season response to temperature depends obviously on local thermal conditions, namely, either the negative response of the start date or the

  12. A longitudinal study of serum insulin and insulin resistance as predictors of weight and body fat gain in African American and Caucasian children.

    Science.gov (United States)

    Sedaka, N M; Olsen, C H; Yannai, L E; Stutzman, W E; Krause, A J; Sherafat-Kazemzadeh, R; Condarco, T A; Brady, S M; Demidowich, A P; Reynolds, J C; Yanovski, S Z; Hubbard, V S; Yanovski, J A

    2017-01-01

    The influence of insulin and insulin resistance (IR) on children's weight and fat gain is unclear. To evaluate insulin and IR as predictors of weight and body fat gain in children at high risk for adult obesity. We hypothesized that baseline IR would be positively associated with follow-up body mass index (BMI) and fat mass. Two hundred and forty-nine healthy African American and Caucasian children aged 6-12 years at high risk for adult obesity because of early-onset childhood overweight and/or parental overweight were followed for up to 15 years with repeated BMI and fat mass measurements. We examined baseline serum insulin and homeostasis model of assessment-IR (HOMA-IR) as predictors of follow-up BMI Z-score and fat mass by dual-energy X-ray absorptiometry in mixed model longitudinal analyses accounting for baseline body composition, pubertal stage, sociodemographic factors and follow-up interval. At baseline, 39% were obese (BMI⩾95th percentile for age/sex). Data from 1335 annual visits were examined. Children were followed for an average of 7.2±4.3 years, with a maximum follow-up of 15 years. After accounting for covariates, neither baseline insulin nor HOMA-IR was significantly associated with follow-up BMI (Ps>0.26), BMIz score (Ps>0.22), fat mass (Ps>0.78) or fat mass percentage (Ps>0.71). In all models, baseline BMI (PHOMA-IR that suggested less gain in mass among those with greater insulin or IR. The opposite was found in some models restricted to children with obesity at baseline. In middle childhood, BMI and fat mass, but not insulin or IR, are strong predictors of children's gains in BMI and fat mass during adolescence.

  13. Multidrug-Resistant Mycobacterium tuberculosis of the Latin American Mediterranean Lineage, Wrongly Identified as Mycobacterium pinnipedii (Spoligotype International Type 863 [SIT863]), Causing Active Tuberculosis in South Brazil

    KAUST Repository

    Dalla Costa, Elis R.

    2015-09-23

    We recently detected the spoligotype patterns of strains of Mycobacterium pinnipedii, a species of the Mycobacterium tuberculosis complex, in sputum samples from nine cases with pulmonary tuberculosis residing in Porto Alegre, South Brazil. Because this species is rarely encountered in humans, we further characterized these nine isolates by additional genotyping techniques, including 24-locus mycobacterial interspersed repetitive-unit–variable-number tandem-repeat (MIRU-VNTR) typing, verification of the loci TbD1, RD9, pks15/1, RDRio, and fbpC, the insertion of IS6110 at a site specific to the M. tuberculosis Latin American Mediterranean (LAM) lineage, and whole-genome sequencing. The combined analysis of these markers revealed that the isolates are in fact M. tuberculosis and more specifically belong to the LAM genotype. Most of these isolates (n = 8) were shown to be multidrug resistant (MDR), which prompted us to perform partial sequencing of the rpoA, rpoB, rpoC, katG, and inhA genes. Seven isolates (77.8%) carried the S315T mutation in katG, and one of these (11%) also presented the C(−17)T single-nucleotide polymorphism (SNP) in inhA. Interestingly, six of the MDR isolates also presented an undescribed insertion of 12 nucleotides (CCA GAA CAA CCC) in codon 516 of rpoB. No putative compensatory mutation was found in either rpoA or rpoC. This is the first report of an M. tuberculosis LAM family strain with a convergent M. pinnipedii spoligotype. These spoligotypes are observed in genotype databases at a modest frequency, highlighting that care must be taken when identifying isolates in the M. tuberculosis complex on the basis of single genetic markers.

  14. Studies of the pedestal structure and inter-ELM pedestal evolution in JET with the ITER-like wall

    Science.gov (United States)

    Maggi, C. F.; Frassinetti, L.; Horvath, L.; Lunniss, A.; Saarelma, S.; Wilson, H.; Flanagan, J.; Leyland, M.; Lupelli, I.; Pamela, S.; Urano, H.; Garzotti, L.; Lerche, E.; Nunes, I.; Rimini, F.; Contributors, JET

    2017-11-01

    The pedestal structure of type I ELMy H-modes has been analysed for JET with the ITER-like Wall (JET-ILW). The electron pressure pedestal width is independent of ρ * and increases proportionally to  √β pol,PED. Additional broadening of the width is observed, at constant β pol, PED, with increasing ν * and/or neutral gas injection and the contribution of atomic physics effects in setting the pedestal width cannot as yet be ruled out. Neutral penetration alone does not determine the shape of the edge density profile in JET-ILW. The ratio of electron density to electron temperature scale lengths in the edge transport barrier region, η e, is of order 2-3 within experimental uncertainties. Existing understanding, represented in the stationary linear peeling-ballooning mode stability and the EPED pedestal structure models, is extended to the dynamic evolution between ELM crashes in JET-ILW, in order to test the assumptions underlying these two models. The inter-ELM temporal evolution of the pedestal structure in JET-ILW is not unique, but depends on discharge conditions, such as heating power and gas injection levels. The strong reduction in p e,PED with increasing D 2 gas injection at high power is primarily due to clamping of \

  15. Density and magnetic fluctuations in type III-ELM pedestal evolution in JET: experimental and numerical characterization

    Science.gov (United States)

    De Masi, G.; Predebon, I.; Spagnolo, S.; Meneses, L.; Delabie, E.; Lupelli, I.; Hillesheim, J. C.; Maggi, C.; Contributors, JET

    2018-04-01

    Density and magnetic fluctuation measurements in low-β type-III ELM discharges are obtained in the Joint European Torus (JET). They are observed during the inter-ELM pedestal evolution, after the LH transition phase, at about 60-70 kHz. Density fluctuations are measured with a correlation reflectometer system installed on the low-field side and they are localized at the pedestal top. Magnetic fluctuations with a spatial scale k_yρ_i˜ 0.1 are measured through a high resolution coil array. The main features and the relations with local plasma parameters are presented. The nature of these fluctuations is discussed along with linear gyrokinetic simulations. Ion temperature gradient (ITG) modes are the dominant instabilities in the frequency range of interest. In terms of radial localization, typical oscillation frequency and qualitative relation with the possible linear drive, ITG modes are consistent with the experimental density fluctuations measurements. Micro-tearing modes (MTMs), found unstable with a lower growth rate, appear a possible explanation for magnetic fluctuations in terms of typical wavenumbers and direction of propagation.

  16. Detection of linezolid resistance due to the optrA gene in Enterococcus faecalis from poultry meat from the American continent (Colombia)

    DEFF Research Database (Denmark)

    Cavaco, Lina; Bernal, J F; Zankari, Ea

    2017-01-01

    Three Enterococcus isolates obtained from retail chicken collected in 2010-11 as part of the Colombian Integrated Program for Antimicrobial Resistance Surveillance (COIPARS) showed reduced susceptibility towards linezolid (MIC 8 mg/L). This study aimed at characterizing the isolates resistant...... to linezolid and detecting the resistance mechanism. Strains were analysed in 2011-12 without successful detection of the resistance mechanism. All isolates were found negative for the cfr gene and no 23S rRNA mutations were detected. In 2016, with the novel resistance gene optrA being described, the WGS data......A gene encoding resistance to linezolid and phenicols. Additional screening of 37 enterococci strains from the same study did not detect any further positives. Typing showed that two of the isolates belong to ST59, while the last belongs to ST489. All isolates carry genes encoding resistance to macrolide...

  17. Investigation of erosion mechanisms and erosion products in divertor armour materials under conditions relevant to elms and mitigated disruptions in ITER

    International Nuclear Information System (INIS)

    Safronov, V.M.; Arkhipov, N.I.; Klimov, N.S.; Kovalenko, D.V.; Moskaleva, A.A.; Podkovyrov, V.L.; Toporkov, D.A.; Zhitlukhin, A.M.; Landman, I.S.; Poznyak, I.M.

    2008-01-01

    Carbon fibre composite (CFC) and tungsten were irradiated by intense plasma streams at plasma gun facilities MK-200UG and QSPA-T. The targets were tested by plasma loads relevant to Edge Localised Modes (ELM) and mitigated disruptions in ITER. Onset condition of material erosion and properties of erosion products have been studied

  18. The effects of grazing on the spatial pattern of elm (Ulmus pumila L.) in the sparse woodland steppe of Horqin Sandy Land in northeastern China

    Science.gov (United States)

    Zhang, M.; Wu, J.; Tang, Y.

    2016-04-01

    The aim of this study was to explore the effects of grazing on the formation of the spatial pattern of elm growth in a sparse woodland steppe. We used a point pattern method to analyze the elm trees within different diameter at breast height (DBH) classes in both grazed and fenced plots, which were established in Horqin Sandy Land of northeastern China. The results showed that, in the grazed plot, the distances where transformation between random and clustered patterns occurred in class 1 (10 cm ≤ DBH ≤ 15 cm) and class 2 (15 cm 20 cm) were 3.13, 3.13 and 7.85 m, respectively. In the fenced plot, at distances larger than 67.72 m there was a negative association between classes 1 and 2, which was also the case between classes 2 and 3 and between classes 1 and 3 for distances greater than 104.09 and 128.54 m, respectively. Meanwhile, negative associations occurred only at distances larger than 29.38 m in the grazed plot. These findings suggest that grazing reduced the competition intensity between elm trees; and therefore, grazing management could be an effective strategy used to regulate the elm population in the degraded sandy land of northern China.

  19. Spatial and temporal nature of reactive oxygen species production and programmed cell death in elm (Ulmus pumila L.) seeds during controlled deterioration.

    Science.gov (United States)

    Hu, Die; Ma, Gang; Wang, Qiong; Yao, Jinghan; Wang, Yu; Pritchard, Hugh W; Wang, Xiaofeng

    2012-11-01

    Seed deterioration is poorly understood and remains an active area for research. Seeds of elm (Ulmus pumila L.) were aged at 37 °C above water [controlled deterioration treatment (CDT)] for various lengths of time to assess programmed cell death (PCD) and reactive oxygen species (ROS) product in embryonic tissues during a 5 d period. The hallmarks of PCD were identified in the elm seeds during CDT including TUNEL experiments, DNA laddering, cytochrome c (cyt c) leakage and enzymatic activities. These analyses indicated that PCD occurred systematically and progressively in deteriorated elm seeds. Cyt c release and increase in caspase-3-like/DEVDase activity occurred during CDT, which could be suppressed by ascorbic acid (AsA) and caspase-3 inhibitor Ac-DEVD-CHO, respectively. In situ localization of ROS production indicated that the distinct spatial-temporal signature of ROS during CDT coincided with the changes in PCD hallmark features. Multiple antioxidant elements were activated during the first few days of CDT, but were subsequently depleted as PCD progressed. Taken together, our findings identify PCD as a key mechanism that occurs asymmetrically during elm seeds CDT and suggest an important role for PCD in seeds deterioration. © 2012 Blackwell Publishing Ltd.

  20. ICGA-PSO-ELM approach for accurate multiclass cancer classification resulting in reduced gene sets in which genes encoding secreted proteins are highly represented.

    Science.gov (United States)

    Saraswathi, Saras; Sundaram, Suresh; Sundararajan, Narasimhan; Zimmermann, Michael; Nilsen-Hamilton, Marit

    2011-01-01

    A combination of Integer-Coded Genetic Algorithm (ICGA) and Particle Swarm Optimization (PSO), coupled with the neural-network-based Extreme Learning Machine (ELM), is used for gene selection and cancer classification. ICGA is used with PSO-ELM to select an optimal set of genes, which is then used to build a classifier to develop an algorithm (ICGA_PSO_ELM) that can handle sparse data and sample imbalance. We evaluate the performance of ICGA-PSO-ELM and compare our results with existing methods in the literature. An investigation into the functions of the selected genes, using a systems biology approach, revealed that many of the identified genes are involved in cell signaling and proliferation. An analysis of these gene sets shows a larger representation of genes that encode secreted proteins than found in randomly selected gene sets. Secreted proteins constitute a major means by which cells interact with their surroundings. Mounting biological evidence has identified the tumor microenvironment as a critical factor that determines tumor survival and growth. Thus, the genes identified by this study that encode secreted proteins might provide important insights to the nature of the critical biological features in the microenvironment of each tumor type that allow these cells to thrive and proliferate.

  1. "Francisco Maestas et al. v. George H. Shone et al.": Mexican American Resistance to School Segregation in the Hispano Homeland, 1912-1914

    Science.gov (United States)

    Donato, Ruben; Guzmán, Gonzalo; Hanson, Jarrod

    2017-01-01

    The authors in this article argue that the "Francisco Maestas et al. vs. George H. Shone et al." (1914) case is one of the earliest Mexican American challenges to school segregation in the United States. Unidentified for over a century, the lawsuit took place in southern Colorado, a region of the nation where Mexican Americans have deep…

  2. Massive sequencing of Ulmus minor's transcriptome provides new molecular tools for a genus under the constant threat of Dutch elm disease.

    Science.gov (United States)

    Perdiguero, Pedro; Venturas, Martin; Cervera, María Teresa; Gil, Luis; Collada, Carmen

    2015-01-01

    Elms, especially Ulmus minor and U. americana, are carrying out a hard battle against Dutch elm disease (DED). This vascular wilt disease, caused by Ophiostoma ulmi and O. novo-ulmi, appeared in the twentieth century and killed millions of elms across North America and Europe. Elm breeding and conservation programmes have identified a reduced number of DED tolerant genotypes. In this study, three U. minor genotypes with contrasted levels of tolerance to DED were exposed to several biotic and abiotic stresses in order to (i) obtain a de novo assembled transcriptome of U. minor using 454 pyrosequencing, (ii) perform a functional annotation of the assembled transcriptome, (iii) identify genes potentially involved in the molecular response to environmental stress, and (iv) develop gene-based markers to support breeding programmes. A total of 58,429 putative unigenes were identified after assembly and filtering of the transcriptome. 32,152 of these unigenes showed homology with proteins identified in the genome from the most common plant model species. Well-known family proteins and transcription factors involved in abiotic, biotic or both stresses were identified after functional annotation. A total of 30,693 polymorphisms were identified in 7,125 isotigs, a large number of them corresponding to single nucleotide polymorphisms (SNPs; 27,359). In a subset randomly selected for validation, 87% of the SNPs were confirmed. The material generated may be valuable for future Ulmus gene expression, population genomics and association genetics studies, especially taking into account the scarce molecular information available for this genus and the great impact that DED has on elm populations.

  3. Massive sequencing of Ulmus minor’s transcriptome provides new molecular tools for a genus under the constant threat of Dutch elm disease

    Science.gov (United States)

    Perdiguero, Pedro; Venturas, Martin; Cervera, María Teresa; Gil, Luis; Collada, Carmen

    2015-01-01

    Elms, especially Ulmus minor and U. americana, are carrying out a hard battle against Dutch elm disease (DED). This vascular wilt disease, caused by Ophiostoma ulmi and O. novo-ulmi, appeared in the twentieth century and killed millions of elms across North America and Europe. Elm breeding and conservation programmes have identified a reduced number of DED tolerant genotypes. In this study, three U. minor genotypes with contrasted levels of tolerance to DED were exposed to several biotic and abiotic stresses in order to (i) obtain a de novo assembled transcriptome of U. minor using 454 pyrosequencing, (ii) perform a functional annotation of the assembled transcriptome, (iii) identify genes potentially involved in the molecular response to environmental stress, and (iv) develop gene-based markers to support breeding programmes. A total of 58,429 putative unigenes were identified after assembly and filtering of the transcriptome. 32,152 of these unigenes showed homology with proteins identified in the genome from the most common plant model species. Well-known family proteins and transcription factors involved in abiotic, biotic or both stresses were identified after functional annotation. A total of 30,693 polymorphisms were identified in 7,125 isotigs, a large number of them corresponding to single nucleotide polymorphisms (SNPs; 27,359). In a subset randomly selected for validation, 87% of the SNPs were confirmed. The material generated may be valuable for future Ulmus gene expression, population genomics and association genetics studies, especially taking into account the scarce molecular information available for this genus and the great impact that DED has on elm populations. PMID:26257751

  4. Massive sequencing of Ulmus minor's transcriptome provides new molecular tools for a genus under the constant threat of Dutch elm disease

    Directory of Open Access Journals (Sweden)

    Pedro ePerdiguero

    2015-07-01

    Full Text Available Elms, especially Ulmus minor and Ulmus americana, are carrying out a hard battle against Dutch elm disease (DED. This vascular wilt disease, caused by Ophiostoma ulmi and O. novo-ulmi, appeared in the twentieth century and killed millions of elms across North America and Europe. Elm breeding and conservation programmes have identified a reduced number of DED tolerant genotypes. In this study, three U. minor genotypes with contrasted levels of tolerance to DED were exposed to several biotic and abiotic stresses in order to (i obtain a de novo assembled transcriptome of U. minor using 454 pyrosequencing, (ii perform a functional annotation of the assembled transcriptome, (iii identify genes potentially involved in the molecular response to environmental stress, and (iv develop gene-based markers to support breeding programmes. A total of 58,429 putative unigenes were identified after assembly and filtering of the transcriptome. 32,152 of these unigenes showed homology with proteins identified in the genome from the most common plant model species. Well-known family proteins and transcription factors involved in abiotic, biotic or both stresses were identified after functional annotation. A total of 30,693 polymorphisms were identified in 7,125 isotigs, a large number of them corresponding to SNPs (27,359. In a subset randomly selected for validation, 87 % of the SNPs were confirmed. The material generated may be valuable for future Ulmus gene expression, population genomics and association genetics studies, especially taking into account the scarce molecular information available for this genus and the great impact that DED has on elm populations.

  5. Effect of Eliminase gene (elmA) Deletion on Heparosan Production and Shedding in Escherichia coli K5

    Science.gov (United States)

    Hickey, Anne Marie; Bhaskar, Ujjwal; Linhardt, Robert J.; Dordick, Jonathan S.

    2013-01-01

    E. coli K5 produces heparosan and sheds it into the growth medium in a temperature dependent manner. The shedding is believed to be controlled, at least in part, by enzyme action on the cell-associated capsular polysaccharide, heparosan. One candidate enzyme in such shedding is eliminase. The eliminase gene (elmA) was deleted from the genome of E. coli K5 and its effect on secreted and cell-associated heparosan was investigated. Deletion of the eliminase gene resulted in a significant reduction in heparosan shedding into the medium and heparosan content in the capsule of the cells, indicating its pivotal role in heparosan synthesis and shedding by E. coli K5. PMID:23583654

  6. Transcriptomic characterization of gall tissue of Japanese elm tree (Ulmus davidiana var. japonica) induced by the aphid Tetraneura nigriabdominalis.

    Science.gov (United States)

    Takei, Mami; Ito, Shinsaku; Tanaka, Keisuke; Ishige, Taichiro; Suzuki, Yoshihito

    2017-06-01

    Insect galls are abnormal plant tissues induced by parasitic insect(s) for use as their habitat. In previous work, we suggested that gall tissues induced by the aphid Tetraneura nigriabdominalis on Japanese elm trees are less responsive than leaf tissues to jasmonic acid (JA), which is involved in the production of volatile organic compounds as a typical defensive reaction of plants against attack by insect pests. A comprehensive analysis of gene expression by RNA sequencing indicated that the number of JA responsive genes was markedly lower in gall tissues than in leaf tissues. This suggests that gall tissues are mostly defective in JA signaling, although JA signaling is not entirely compromised in gall tissue. Gene ontology analysis sheds light on some stress-related unigenes with higher expression levels in gall tissues, suggesting that host plants sense aphids as a biotic stress but are defective in the JA-mediated defense response in gall tissues.

  7. Cracking behavior of tungsten armor under ELM-like thermal shockloads II: A revised prediction for crack appearance map

    Directory of Open Access Journals (Sweden)

    Muyuan Li

    2016-12-01

    Full Text Available In this work, the surface cracking features of tungsten armor under thermal shock loads by edge-localized mode (ELM were investigated by means of computational fracture mechanics analysis. For the simulation it was assumed that a small crack was initiated at low temperature after the shut-off of thermal load in contrast to the previous studies where the presence of a crack before thermal loading was assumed. The threshold power density for surface cracking was predicted to range between 0.3 and 0.6GW/m2 while the threshold of base temperature lay between 200 and 400°C. The theoretically predicted damage map agreed well with the experimental data from electron beam irradiation tests. The current simulation model turned out to match better to the real experimental observation than the previous predictions where the threshold base temperature lies roughly between 400 and 600°C.

  8. Experimental investigation of vapor shielding effects induced by ELM-like pulsed plasma loads using the double plasma gun device

    Science.gov (United States)

    Sakuma, I.; Kikuchi, Y.; Kitagawa, Y.; Asai, Y.; Onishi, K.; Fukumoto, N.; Nagata, M.

    2015-08-01

    We have developed a unique experimental device of so-called double plasma gun, which consists of two magnetized coaxial plasma gun (MCPG) devices, in order to clarify effects of vapor shielding on material erosion due to transient events in magnetically confined fusion devices. Two ELM-like pulsed plasmas produced by the two MCPG devices were injected into a target chamber with a variable time difference. For generating ablated plasmas in front of a target material, an aluminum foil sample in the target chamber was exposed to a pulsed plasma produced by the 1st MCPG device. The 2nd pulsed plasma was produced with a time delay of 70 μs. It was found that a surface absorbed energy measured by a calorimeter was reduced to ∼66% of that without the Al foil sample. Thus, the reduction of the incoming plasma energy by the vapor shielding effect was successfully demonstrated in the present experiment.

  9. Experimental investigation of vapor shielding effects induced by ELM-like pulsed plasma loads using the double plasma gun device

    Energy Technology Data Exchange (ETDEWEB)

    Sakuma, I., E-mail: eu13z002@steng.u-hyogo.ac.jp; Kikuchi, Y.; Kitagawa, Y.; Asai, Y.; Onishi, K.; Fukumoto, N.; Nagata, M.

    2015-08-15

    We have developed a unique experimental device of so-called double plasma gun, which consists of two magnetized coaxial plasma gun (MCPG) devices, in order to clarify effects of vapor shielding on material erosion due to transient events in magnetically confined fusion devices. Two ELM-like pulsed plasmas produced by the two MCPG devices were injected into a target chamber with a variable time difference. For generating ablated plasmas in front of a target material, an aluminum foil sample in the target chamber was exposed to a pulsed plasma produced by the 1st MCPG device. The 2nd pulsed plasma was produced with a time delay of 70 μs. It was found that a surface absorbed energy measured by a calorimeter was reduced to ∼66% of that without the Al foil sample. Thus, the reduction of the incoming plasma energy by the vapor shielding effect was successfully demonstrated in the present experiment.

  10. Reactive oxygen species-provoked mitochondria-dependent cell death during ageing of elm (Ulmus pumila L.) seeds.

    Science.gov (United States)

    Wang, Yu; Li, Ying; Xue, Hua; Pritchard, Hugh W; Wang, Xiaofeng

    2015-02-01

    Previous studies have shown that controlled deterioration treatment (CDT) induces programmed cell death in elm (Ulmus pumila L.) seeds, which undergo certain fundamental processes that are comparable to apoptosis in animals. In this study, the essential characteristics of mitochondrial physiology in elm seeds during CDT were identified by cellular ultrastructural analysis, whole-body optical imaging, Western blotting and semi-quantitative RT-PCR. The alteration in mitochondrial morphology was an early event during CDT, as indicated by progressive dynamic mitochondrial changes and rupture of the mitochondrial outer membrane; loss of mitochondrial transmembrane potential (Δψ(m)) ensued, and mitochondrial ATP levels decreased. The mitochondrial permeability transition pore inhibitor cyclosporine A effectively suppressed these changes during ageing. The in situ localization of production of reactive oxygen species (ROS), and evaluation of the expression of voltage-dependent anion-selective channel and cyclophilin D indicated that the levels of mitochondrial permeability transition pore components were positively correlated with ROS production, leading to an imbalance of the cellular redox potential and ultimately to programmed cell death. Pre-incubation with ascorbic acid slowed loss of mitochondrial Δψ(m), and decreased the effect of CDT on seed viability. However, there were no significant changes in multiple antioxidant elements or chaperones in the mitochondria during early stages of ageing. Our results indicate that CDT induces dynamic changes in mitochondrial physiology via increased ROS production, ultimately resulting in an irreversible loss of seed viability. © 2014 The Authors The Plant Journal © 2014 John Wiley & Sons Ltd.

  11. Emerging resistance among bacterial pathogens in the intensive care unit – a European and North American Surveillance study (2000–2002

    Directory of Open Access Journals (Sweden)

    Thornsberry Clyde

    2004-07-01

    Full Text Available Abstract Background Globally ICUs are encountering emergence and spread of antibiotic-resistant pathogens and for some pathogens there are few therapeutic options available. Methods Antibiotic in vitro susceptibility data of predominant ICU pathogens during 2000–2 were analyzed using data from The Surveillance Network (TSN Databases in Europe (France, Germany and Italy, Canada, and the United States (US. Results Oxacillin resistance rates among Staphylococcus aureus isolates ranged from 19.7% to 59.4%. Penicillin resistance rates among Streptococcus pneumoniae varied from 2.0% in Germany to as high as 20.2% in the US; however, ceftriaxone resistance rates were comparably lower, ranging from 0% in Germany to 3.4% in Italy. Vancomycin resistance rates among Enterococcus faecalis were ≤ 4.5%; however, among Enterococcus faecium vancomycin resistance rates were more frequent ranging from 0.8% in France to 76.3% in the United States. Putative rates of extended-spectrum β-lactamase (ESBL production among Enterobacteriaceae were low, Escherichia coli in the five countries studied. Ceftriaxone resistance rates were generally lower than or similar to piperacillin-tazobactam for most of the Enterobacteriaceae species examined. Fluoroquinolone resistance rates were generally higher for E. coli (6.5% – 13.9%, Proteus mirabilis (0–34.7%, and Morganella morganii (1.6–20.7% than other Enterobacteriaceae spp (1.5–21.3%. P. aeruginosa demonstrated marked variation in β-lactam resistance rates among countries. Imipenem was the most active compound tested against Acinetobacter spp., based on resistance rates. Conclusion There was a wide distribution in resistance patterns among the five countries. Compared with other countries, Italy showed the highest resistance rates to all the organisms with the exception of Enterococcus spp., which were highest in the US. This data highlights the differences in resistance encountered in intensive care units in

  12. Análisis comparativo de la disponibilidad léxica en español como lengua extranjera (ELE y lengua materna (ELM

    Directory of Open Access Journals (Sweden)

    Šifrar Kajan, Marjana

    2012-09-01

    Full Text Available El objetivo del presente trabajo es comparar la disponibilidad léxica de los estudiantes eslovenos de ELE con la disponibilidad léxica de los estudiantes españoles de ELM, y detectar las diferencias o similitudes léxicas entre los hablantes extranjeros y nativos de español en diez campos semánticos: partes del cuerpo, la ropa, la casa, alimentos y bebidas, la ciudad, el campo, medios de transporte, los animales, juegos y distracciones, y profesiones y oficios. Quedan así expuestas las grandes discrepancias entre el léxico más disponible en ELE y ELM, y en relación con el Plan Curricular. A partir de los resultados se propone la aplicación pedagógica de la planificación léxica en la enseñanza de ELE.

  13. Investigation on the Scratch Strength of Clear Paints Used in Furniture Industries on the Wood Species Beech, Elm, Alder and Spruce

    Directory of Open Access Journals (Sweden)

    Mohammad Ghofrani

    2014-05-01

    Full Text Available In This research, the scratch strength (Cross-Cut Test of clear paints (nitrocellulose lacquers and acid catalyst lacquers of wood species Beech, Elm, Alder and spruce were studied as a function of moisture content (MC of the samples. For this purpose, lumbers (550×110×12 mm were cut from sapwood in tangential surfaces and were air dried for one month according to wood drying procedures. Then, for pre-conditioning of moisture content, at the levels of 8%, 12% and 15%, the samples were placed in three clima rooms. Then, finish applied and strength tests were performed. The results revealed that for acid catalyst lacquers the highest scratch strength (10.4% belongs to Elm wood with 8% moisture content, and the lowest scratch strength (53.6% belongs to Spruce wood with nitrocellulose lacquers having 15% moisture content.

  14. The effect of Tetraneura ulmi L. galling process on the activity of amino acid decarboxylases and the content of biogenic amines in Siberian elm tissues.

    Science.gov (United States)

    Kmieć, K; Sempruch, C; Chrzanowski, G; Czerniewicz, P

    2018-02-01

    Tetraneura ulmi (L.), a member of Eriosomatinae subfamily, is one of the gall-forming aphids occurring on elms. Sap-sucking behaviour of founding mothers results in the formation of new plant organs. This study documents the changes in the content of plant biogenic amines (putrescine, cadaverine, spermidine, tryptamine, spermine and histamine) and key enzymes of their biosynthesis: lysine decarboxylase (LDC), tyrosine decarboxylase and ornithine decarboxylase (ODC) in galls and other parts of Siberian elm (Ulmus pumila L.) leaves during the galling process. The direction and intensity of these changes for particular amines and enzymes were dependent on the stage of gall development and part of the galling leaf. Generally, the amine content tended to increase in gall tissues during the 1st and 2nd period of the galling process and decreased in later phases. LDC and ODC activities were markedly enhanced, especially in gall tissues at the initial stage of the galling process.

  15. The H-mode pedestal, ELMs and TF ripple effects in JT-60U/JET dimensionless identity experiments

    International Nuclear Information System (INIS)

    Saibene, G.; Oyama, N.; Loennroth, J.; Andrew, Y.; Luna, E. de la; Giroud, C.; Huysmans, G.T.A.; Kamada, Y.; Kempenaars, M.A.H.; Loarte, A.; Donald, D. Mc; Nave, M.M.F.; Meiggs, A.; Parail, V.; Sartori, R.; Sharapov, S.; Stober, J.; Suzuki, T.; Takechi, M.; Toi, K.; Urano, H.

    2007-01-01

    This paper summarizes results of dimensionless identity experiments in JT-60U and JET, aimed at the comparison of the H-mode pedestal and ELM behaviour in the two devices. Given their similar size, dimensionless matched plasmas are also similar in their dimensional parameters (in particular, the plasma minor radius a is the same in JET and JT-60U). Power and density scans were carried out at two values of I p , providing a q scan (q 95 = 3.1 and 5.1) with fixed (and matched) toroidal field. Contrary to initial expectations, a dimensionless match between the two devices was quite difficult to achieve. In general, p ped in JT-60U is lower than in JET and, at low q, the pedestal pressure of JT-60U with a Type I ELMy edge is matched in JET only in the Type III ELM regime. At q 95 = 5.1, a dimensionless match in ρ*, ν* and β p,ped is obtained with Type I ELMs, but only with low power JET H-modes. These results motivated a closer investigation of experimental conditions in the two devices, to identify possible 'hidden' physics that prevents obtaining a good match of pedestal values over a large range of plasmas parameters. Ripple-induced ion losses of the medium bore plasma used in JT-60U for the similarity experiments are identified as the main difference with JET. The magnitude of the JT-60U ripple losses is sufficient to induce counter-toroidal rotation in co-injected plasma. The influence of ripple losses was demonstrated at q 95 = 5.1: reducing ripple losses by ∼2 (from 4.3 to 1.9 MW) by replacing positive with negative neutral beam injection at approximately constant P in resulted in an increased p ped in JT-60U, providing a good match to full power JET H-modes. At the same time, the counter-toroidal rotation decreased. Physics mechanisms relating ripple losses to pedestal performance are not yet identified, and the possible role of velocity shear in the pedestal stability, as well as the possible influence of ripple on thermal ion transport are briefly

  16. ELM-induced melting: assessment of shallow melt layer damage and the power handling capability of tungsten in a linear plasma device

    Czech Academy of Sciences Publication Activity Database

    Morgan, T.W.; van Eden, G.G.; de Kruif, T.M.; van den Berg, A.; Matějíček, Jiří; Chráska, Tomáš; De Temmerman, G.

    -, T159 (2014), 014022-014022 ISSN 0031-8949. [International Conference on Plasma-Facing Material s and Components for Fusion Applications/14./. Jülich, 13.05.2013-17.05.2013] Institutional support: RVO:61389021 Keywords : melting * tungsten * ELMs * divertor * ITER * DEMO Subject RIV: JG - Metallurgy Impact factor: 1.126, year: 2014 http://iopscience.iop.org/1402-4896/2014/T159/014022/pdf/1402-4896_2014_T159_014022.pdf

  17. A Systems Evaluation of the Environmental Impact of the Aubrey Reservoir Project on Elm Fork of the Trinity River in North Texas.

    Science.gov (United States)

    1972-06-01

    Butterflies Bees Beetles Other invertebrates 8 0.33 Millipedes Earthworms Roundworms Pill bugs Carnivores Insectivorous Birds 6 1.00 Swallows Flycatchers...properties to toxicity and death of the affected organism. Adequate toxicological data specific for many of these compounds is insufficient. However...On the high and drier terraces, cedar elm, Ulmus crassifolia, predominates. Common associates are Gleditsia tricanthos, honey locust and Morus rubra

  18. QUIESCENT H-MODE, AN ELM-FREE HIGH-CONFINEMENT MODE ON DIII-D WITH POTENTIAL FOR STATIONARY STATE OPERATION

    Energy Technology Data Exchange (ETDEWEB)

    WEST,WP; BURRELL,KH; deGRASSIE,JS; DOYLE,EJ; GREENFIELD,CM; LASNIER,CJ; SNYDER,PB; ZENG,L

    2003-08-01

    OAK-B135 The quiescent H-mode (QH-mode) is an ELM-free and stationary state mode of operation discovered on DIII-D. This mode achieves H-mode levels of confinement and pedestal pressure while maintaining constant density and radiated power. The elimination of edge localized modes (ELMs) and their large divertor loads while maintaining good confinement and good density control is of interest to next generation tokamaks. This paper reports on the correlations found between selected parameters in a QH-mode database developed from several hundred DIII-D counter injected discharges. Time traces of key plasma parameters from a QH-mode discharge are shown. On DIII-D the negative going plasma current (a) indicates that the beam injection direction is counter to the plasma current direction, a common feature of all QH-modes. The D{sub {alpha}} time behavior (c) shows that soon after high powered beam heating (b) is applied, the discharge makes a transition to ELMing H-mode, then the ELMs disappear, indicating the start of the QH period that lasts for the remainder of the high power beam heating (3.5 s). Previously published work showing density and temperature profiles indicates that long-pulse, high-triangularity QH discharges develop an internal transport barrier in combination with the QH edge barrier. These discharges are known as quiescent, double-barrier discharges (QDB). The H-factor (d) and stored energy (c) rise then saturate at a constant level and the measured axial and minimum safety factors remain above 1.0 for the entire QH duration. During QDB operation the performance of the plasma can be very good, with {beta}{sub N}*H{sub 89L} product reaching 7 for > 10 energy confinement times. These discharges show promise that a stationary state can be achieved.

  19. Resisting Official Knowledge: The Incorporation and Abjection of Race and Poverty in High School American History Textbooks, 1960s-2000s

    Science.gov (United States)

    Kearl, Benjamin Kelsey

    2014-01-01

    Through an interpretive analysis of how high school American history textbooks depict the urban-riots of the late-1960s, in this article the author discusses how textbooks incorporate and abject official knowledge related to the intersections of race and poverty. Incorporation is related with Raymond Williams' theory of the selective tradition and…

  20. Dynamic behavior of detached recombining plasmas during ELM-like plasma heat pulses in the divertor plasma simulator NAGDIS-II

    International Nuclear Information System (INIS)

    Uesugi, Y.; Hattori, N.; Nishijima, D.; Ohno, N.; Takamura, S.

    2001-01-01

    It has been recognized that the ELMs associated with a good confinement at the edge, such as H-mode, must bring an enormous energy to the divertor target plate through SOL and detached plasmas. The understanding of the ELM energy transport through SOL to the divertor target is rather poor at the moment, which leads to an ambiguous estimation of the deposited heat load on the divertor target in ITER. In the present work the ELM-like plasma heat pulse is generated by rf heating in a linear divertor plasma simulator. Energetic electrons with an energy range 10-40 eV are effectively generated by rf heating in low temperature plasmas with (T e )< ∼1 eV. It is observed experimentally that the energetic electrons ionize the highly excited Rydberg atoms quickly, bringing a rapid increase of the ion particle flux to the target, and make the detached plasmas attached to the target. Detailed physical processes about the interaction between the heat pulse with conduction and convection, and detached recombining plasmas are discussed

  1. Transcriptomic identification of ADH1B as a novel candidate gene for obesity and insulin resistance in human adipose tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES.

    Directory of Open Access Journals (Sweden)

    Deidre A Winnier

    Full Text Available Type 2 diabetes (T2D is a complex metabolic disease that is more prevalent in ethnic groups such as Mexican Americans, and is strongly associated with the risk factors obesity and insulin resistance. The goal of this study was to perform whole genome gene expression profiling in adipose tissue to detect common patterns of gene regulation associated with obesity and insulin resistance. We used phenotypic and genotypic data from 308 Mexican American participants from the Veterans Administration Genetic Epidemiology Study (VAGES. Basal fasting RNA was extracted from adipose tissue biopsies from a subset of 75 unrelated individuals, and gene expression data generated on the Illumina BeadArray platform. The number of gene probes with significant expression above baseline was approximately 31,000. We performed multiple regression analysis of all probes with 15 metabolic traits. Adipose tissue had 3,012 genes significantly associated with the traits of interest (false discovery rate, FDR ≤ 0.05. The significance of gene expression changes was used to select 52 genes with significant (FDR ≤ 10(-4 gene expression changes across multiple traits. Gene sets/Pathways analysis identified one gene, alcohol dehydrogenase 1B (ADH1B that was significantly enriched (P < 10(-60 as a prime candidate for involvement in multiple relevant metabolic pathways. Illumina BeadChip derived ADH1B expression data was consistent with quantitative real time PCR data. We observed significant inverse correlations with waist circumference (2.8 x 10(-9, BMI (5.4 x 10(-6, and fasting plasma insulin (P < 0.001. These findings are consistent with a central role for ADH1B in obesity and insulin resistance and provide evidence for a novel genetic regulatory mechanism for human metabolic diseases related to these traits.

  2. Effects of inoculation timing on symptom development in Ulmus americana L.

    Science.gov (United States)

    Garrett L. Beier; Benjamin W. Held; Chad P. Giblin; Robert A. Blanchette

    2017-01-01

    Field inoculation trials are an important component of screening American elms (Ulmus americana) for levels of resistance to Dutch elm disease. A major concern in screening is variability in disease ratings from year to year. Previous studies have demonstrated that timing of inoculation can have a significant impact on disease susceptibility. In...

  3. Ultrastructure of cells of Ulmus americana cultured in vitro and exposed to the culture filtrate of Ceratocystis ulmi

    Science.gov (United States)

    Paula M. Pijut; R. Daniel Lineberger; Subhash C. Domir; Jann M. Ichida; Charles R. Krause

    1990-01-01

    Calli of American elm susceptible and resistant to Dutch elm disease were exposed to a culture filtrate of a pathogenic isolate of Ceratocystis ulmi. Cells from untreated tissue exhibited typical internal composition associated with healthy, actively growing cells. All cells exposed to culture filtrate showed appreciable ultrastructural changes....

  4. An effective method, composed of LAMP and dCAPS, to detect different mutations in fenoxaprop-P-ethyl-resistant American sloughgrass (Beckmannia syzigachne Steud.) populations.

    Science.gov (United States)

    Pan, Lang; Li, Jun; Xia, Wenwen; Zhang, Di; Dong, Liyao

    2015-01-01

    The decreased susceptibility of Beckmannia syzigachne to fenoxaprop-P-ethyl is due to the reliance on it to control grass weeds since the 1990s. Loop-mediated isothermal amplification (LAMP), which is a proven simple, rapid, specific, sensitive and inexpensive assay method, has been used to detect the I1781L mutation in B. syzigachne. In the present study, four sets of primers detected four mutations in B. syzigachne, W2027C, I2041A, D2078G and G2096A, using the LAMP method. Additionally, five newly derived cleaved amplified polymorphic sequence (dCAPS) markers were developed to detect five different mutations. With a method composed of LAMP and dCAPS, 19 fenoxaprop-P-ethyl-resistant B. syzigachne populations collected in 2013 were studied. An effective method, composed of LAMP and dCAPS, to detect five mutations, I1781L, W2027C, I2041A, D2078G and G2096A, in B. syzigachne populations was developed. With this method, a B. syzigachne population resistant to fenoxaprop-P-ethyl can be studied to confirm its constitution. And we determined that the resistance level might be relevant to the mutation type and mutation frequency. The type of mutation and its frequency in fenoxaprop-P-ethyl-resistant B. syzigachne populations can be confirmed to provide appropriate herbicide management. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. Direct Kernel Perceptron (DKP): ultra-fast kernel ELM-based classification with non-iterative closed-form weight calculation.

    Science.gov (United States)

    Fernández-Delgado, Manuel; Cernadas, Eva; Barro, Senén; Ribeiro, Jorge; Neves, José

    2014-02-01

    The Direct Kernel Perceptron (DKP) (Fernández-Delgado et al., 2010) is a very simple and fast kernel-based classifier, related to the Support Vector Machine (SVM) and to the Extreme Learning Machine (ELM) (Huang, Wang, & Lan, 2011), whose α-coefficients are calculated directly, without any iterative training, using an analytical closed-form expression which involves only the training patterns. The DKP, which is inspired by the Direct Parallel Perceptron, (Auer et al., 2008), uses a Gaussian kernel and a linear classifier (perceptron). The weight vector of this classifier in the feature space minimizes an error measure which combines the training error and the hyperplane margin, without any tunable regularization parameter. This weight vector can be translated, using a variable change, to the α-coefficients, and both are determined without iterative calculations. We calculate solutions using several error functions, achieving the best trade-off between accuracy and efficiency with the linear function. These solutions for the α coefficients can be considered alternatives to the ELM with a new physical meaning in terms of error and margin: in fact, the linear and quadratic DKP are special cases of the two-class ELM when the regularization parameter C takes the values C=0 and C=∞. The linear DKP is extremely efficient and much faster (over a vast collection of 42 benchmark and real-life data sets) than 12 very popular and accurate classifiers including SVM, Multi-Layer Perceptron, Adaboost, Random Forest and Bagging of RPART decision trees, Linear Discriminant Analysis, K-Nearest Neighbors, ELM, Probabilistic Neural Networks, Radial Basis Function neural networks and Generalized ART. Besides, despite its simplicity and extreme efficiency, DKP achieves higher accuracies than 7 out of 12 classifiers, exhibiting small differences with respect to the best ones (SVM, ELM, Adaboost and Random Forest), which are much slower. Thus, the DKP provides an easy and fast way

  6. The effect of microbial inocula on the growth of black locust, Siberian elm and silver maple seedlings

    Directory of Open Access Journals (Sweden)

    Hajnal-Jafari Timea

    2014-01-01

    Full Text Available Growth and development of forest plants depend mostly on the soil microbial activity since no mineral or organic fertilizers are applied. Microbial processes can be activated and conditions for plants development improved with the introduction of selected microorganisms in the soil. With the aim of obtaining quality planting material in a shorter period of time, the effects of Azotobacter chroococcum and Streptomyces sp. on the early growth of black locust (Robinia pseudoacacia, Siberian elm (Ulmus pumila and silver-leaf maple (Acer dasycarpum were investigated in this study. Microorganisms were applied individually and in a mixture (1:1. Plant height was measured on the 90th, 120th and 180th day after planting. Plant diameter, as well as the number of actinomycetes and azotobacters was measured at the end of the vegetation period (180 days after planting. Applied microorganisms had a positive effect on the seedling height in all three plant species, with the best effect found in the black locust. Effectiveness of applied microorganisms on seedling diameter was the highest in the silver-leaf maple. The largest number of azotobacters was found in the rhizosphere of black locust. Number of microorganisms from both groups was increased in the inoculated variants. [Projekat Ministarstva nauke Republike Srbije, br. III 43002

  7. Characterization of type-I ELM induced filaments in the far scrape-off layer of ASDEX upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Schmid, Andreas

    2008-03-18

    This thesis focuses on the characterization of filaments and their propagation in the ASDEX Upgrade tokamak. The aim is to provide experimental measurements for understanding the filament formation process and their temporal evolution, and to provide a comprehensive database for an extrapolation to future fusion devices. For this purpose, a new magnetically driven probe for filament measurements has been developed and installed in ASDEX Upgrade. The probe carries several Langmuir probes and a magnetic coil in between. The Langmuir probes allow for measurements of the radial and poloidal/toroidal propagation of filaments as well as for measurements of filament size, density, and their radial (or temporal) evolution. The magnetic coil on the filament probe allows for measurements of currents in the filaments. A set of 7 coils, measuring 3 field components at different positions along the filament, has been used to measure the magnetic signature during an ELM. The aim was, on the one hand, to study which role filaments play for the magnetic structure, and on the other hand if the parallel currents predicted by the sheath damped model could be verified. Filament temperatures have been derived and the corresponding heat transport mechanisms have been studied. (orig.)

  8. Heybridge: A late Iron Age and Roman settlement. Excavations at Elms Farm 1993-5. Volume 2

    Directory of Open Access Journals (Sweden)

    Mark Atkinson

    2015-12-01

    Full Text Available The Late Iron Age, Roman and early Saxon settlement at Elms Farm, Heybridge, Essex was excavated in the mid-1990s, in advance of the construction of a large housing estate by Bovis Homes Ltd. The total development area comprised c. 29 hectares, of which some 18ha were subject to varying degrees of investigation by the Essex County Council Field Archaeology Unit (ECC FAU. The large-scale of the excavations is matched by the substantial and important artefact assemblage recovered, which included 6.4 tonnes of Late Iron Age and Roman pottery, 2,910 Roman coins and over 9000 animal bones. Together this has enabled an appreciation of the development of the settlement over time and space, of the changing functions, status and economy of individual areas and the settlement as a whole, and the issues of transition, change and finally decline. The site revealed evidence for activity from the Bronze Age to the post-medieval period. The evidence for the earliest settlement dates to the Late Iron Age period (mid 1st century BC and is rather fragmentary in nature. However a centrally located shrine, with a series of strip-plots to the north and south were tentatively identified. This settlement was remodelled around the mid 1st century AD, with the creation of a formal infrastructure of metalled roads, as well as a new temple precinct on the earlier sacred site and a reworking of the strip-plots into enclosures. This remodelling spanned the Late Iron Age/early Roman transition period, although the new road network is tentatively dated to the decade or two preceding the Roman conquest. To the north of the settlement area were a number of burials, pyre sites and pyre debris dumps. Early Roman cremations were added to this area slightly later. Some of the pyre sites exhibit higher-status elements, and at least one may have been 'aristocratic', suggesting the presence of a local elite. Reconstruction of settlement at Heybridge by Roger Massey-Ryan The later 1st

  9. Learning from history, predicting the future: the UK Dutch elm disease outbreak in relation to contemporary tree disease threats

    Science.gov (United States)

    Potter, Clive; Harwood, Tom; Knight, Jon; Tomlinson, Isobel

    2011-01-01

    Expanding international trade and increased transportation are heavily implicated in the growing threat posed by invasive pathogens to biodiversity and landscapes. With trees and woodland in the UK now facing threats from a number of disease systems, this paper looks to historical experience with the Dutch elm disease (DED) epidemic of the 1970s to see what can be learned about an outbreak and attempts to prevent, manage and control it. The paper draws on an interdisciplinary investigation into the history, biology and policy of the epidemic. It presents a reconstruction based on a spatial modelling exercise underpinned by archival research and interviews with individuals involved in the attempted management of the epidemic at the time. The paper explores what, if anything, might have been done to contain the outbreak and discusses the wider lessons for plant protection. Reading across to present-day biosecurity concerns, the paper looks at the current outbreak of ramorum blight in the UK and presents an analysis of the unfolding epidemiology and policy of this more recent, and potentially very serious, disease outbreak. The paper concludes by reflecting on the continuing contemporary relevance of the DED experience at an important juncture in the evolution of plant protection policy. PMID:21624917

  10. Experimental evidence for the suitability of ELMing H-mode operation in ITER with regard to core transport of Helium

    International Nuclear Information System (INIS)

    Wade, M.R.; Hillis, D.L.; Burrell, K.H.

    1997-01-01

    Studies have been conducted in DIII-D to assess the viability of the ITER design with regard to helium ash removal, including both global helium exhaust studies and detailed helium transport studies. With respect to helium ash accumulation, the results are encouraging for successful operation of ITER in ELMing H-mode plasmas with conventional high-recycling divertor operation. Helium can be removed from the plasma core with a characteristic time constant of ∼ 8 energy confinement times, even with a central source of helium. Furthermore, the exhaust rate is limited by the pumping efficiency of the system and not by transport of helium within the plasma core. Helium transport studies have shown that DHe/χ eff ∼ 1 in all confinement regimes studied to date and there is little dependence of DHe/χ eff on the normalized gyroradius in dimensionless scaling studies, suggesting that DHe/χ eff will b ∼ 1 in ITER. These observations suggest that helium transport within the plasma core should be sufficient to prevent unacceptable fuel dilution in ITER. However, helium exhaust is also strongly dependent on many factors (e.g. divertor plasma conditions, plasma and baffling geometry, flux amplification, pumping seed) that are difficult to extrapolate. Studies have revealed that the helium diffusivity decreases as the plasma density increases, which is unfavorable to ITER's extremely high density operation. (author). 10 refs, 3 figs

  11. Surface modifications on toughened, fine-grained, recrystallized tungsten with repetitive ELM-like pulsed plasma irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Kikuchi, Y., E-mail: ykikuchi@eng.u-hyogo.ac.jp [Graduate School of Engineering, University of Hyogo, 2167 Shosha, Himeji, 671-2280 Hyogo (Japan); Sakuma, I.; Kitagawa, Y.; Asai, Y.; Onishi, K.; Fukumoto, N.; Nagata, M. [Graduate School of Engineering, University of Hyogo, 2167 Shosha, Himeji, 671-2280 Hyogo (Japan); Ueda, Y. [Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871 (Japan); Kurishita, H. [Institute for Materials Research, Tohoku University, Ibaraki 311-1313 (Japan)

    2015-08-15

    Surface modifications of toughened, fine-grained, recrystallized tungsten (TFGR W) materials with 1.1 wt.% TiC and 3.3 wt.% TaC dispersoids due to repetitive ELM-like pulsed (∼0.15 ms) helium plasma irradiation have been investigated by using a magnetized coaxial plasma gun. No surface cracking at the center part of the TFGR W samples exposed to 20 plasma pulses of ∼0.3 MJ m{sup −2} was observed. The suppression of surface crack formation due to the increase of the grain boundary strength by addition of TiC and TaC dispersoids was confirmed in comparison with a pure W material. On the other hand, surface cracks and small pits appeared at the edge part of the TFGR W sample after the pulsed plasma irradiation. Erosion of the TiC and TaC dispersoids due to the pulsed plasma irradiation could cause the small pits on the surface, resulting in the surface crack formation.

  12. Vapor shielding effects on energy transfer from plasma-gun generated ELM-like transient loads to material surfaces

    Science.gov (United States)

    Kikuchi, Y.; Sakuma, I.; Asai, Y.; Onishi, K.; Isono, W.; Nakazono, T.; Nakane, M.; Fukumoto, N.; Nagata, M.

    2016-02-01

    Energy transfer processes from ELM-like pulsed helium (He) plasmas with a pulse duration of ˜0.1 ms to aluminum (Al) and tungsten (W) surfaces were experimentally investigated by the use of a magnetized coaxial plasma gun device. The surface absorbed energy density of the He pulsed plasma on the W surface measured with a calorimeter was ˜0.44 MJ m-2, whereas it was ˜0.15 MJ m-2 on the Al surface. A vapor layer in front of the Al surface exposed to the He pulsed plasma was clearly identified by Al neutral emission line (Al i) measured with a high time resolution spectrometer, and fast imaging with a high-speed visible camera filtered around the Al i emission line. On the other hand, no clear evaporation in front of the W surface exposed to the He pulsed plasma was observed in the present condition. Discussions on the reduction in the surface absorbed energy density on the Al surface are provided by considering the latent heat of vaporization and radiation cooling due to the Al vapor cloud.

  13. Surface modifications on toughened, fine-grained, recrystallized tungsten with repetitive ELM-like pulsed plasma irradiation

    Science.gov (United States)

    Kikuchi, Y.; Sakuma, I.; Kitagawa, Y.; Asai, Y.; Onishi, K.; Fukumoto, N.; Nagata, M.; Ueda, Y.; Kurishita, H.

    2015-08-01

    Surface modifications of toughened, fine-grained, recrystallized tungsten (TFGR W) materials with 1.1 wt.% TiC and 3.3 wt.% TaC dispersoids due to repetitive ELM-like pulsed (∼0.15 ms) helium plasma irradiation have been investigated by using a magnetized coaxial plasma gun. No surface cracking at the center part of the TFGR W samples exposed to 20 plasma pulses of ∼0.3 MJ m-2 was observed. The suppression of surface crack formation due to the increase of the grain boundary strength by addition of TiC and TaC dispersoids was confirmed in comparison with a pure W material. On the other hand, surface cracks and small pits appeared at the edge part of the TFGR W sample after the pulsed plasma irradiation. Erosion of the TiC and TaC dispersoids due to the pulsed plasma irradiation could cause the small pits on the surface, resulting in the surface crack formation.

  14. Organic compounds in Elm Fork Trinity River water used for public supply near Carrollton, Texas, 2002-05

    Science.gov (United States)

    Ging, Patricia B.; Delzer, Gregory C.; Hamilton, Pixie A.

    2009-01-01

    Organic compounds studied in this U.S. Geological Survey (USGS) assessment generally are man-made, including pesticides, solvents, gasoline hydrocarbons, personal-care and domestic-use products, refrigerants, and propellants. A total of 103 of 277 compounds were detected at least once among the 30 samples of source water for a community water system on the Elm Fork Trinity River near Carrollton, Texas, collected approximately monthly during 2002-05. The diversity of compounds detected indicates a variety of different sources and uses (including wastewater discharge, industrial, agricultural, domestic, and others) and different pathways (including overland runoff and groundwater discharge) to drinking-water supplies. Nine compounds were detected year-round in source-water samples, including chloroform, methyl tert-butyl ether (MTBE), and selected herbicide compounds commonly used in the Trinity River Basin and in other urban areas across the United States. About 90 percent of the 42 compounds detected most frequently in source water (in at least 20 percent of the samples) also were detected most frequently in finished water (after treatment but before distribution). Concentrations for all detected compounds in source and finished water generally were less than 0.1 microgram per liter and always less than human-health benchmarks, which are available for about one-half of the detected compounds.

  15. Biological traits and the complex of parasitoids of the elm pest Orchestes steppensis (Coleoptera: Curculionidae) in Xinjiang, China.

    Science.gov (United States)

    Li, Q; Triapitsyn, S V; Wang, C; Zhong, W; Hu, H-Y

    2018-02-01

    The flee-weevil Orchestes steppensis Korotyaev (Coleoptera: Curculionidae) is a steppe eastern Palaearctic species, notable as a serious pest of elms (Ulmus spp., Ulmaceae), by feeding on the leaves (adults) or mining them heavily (larvae), especially of Ulmus pumila L. in Xinjiang, China. We have corrected the previous misidentifications of this weevil in China as O. alni (L.) or O. mutabilis Boheman and demonstrated that it is likely to be an invasive species in Xinjiang. Prior to this study, natural enemies of O. steppensis were unknown in Xinjiang. Resulting from field investigation and rearing in the laboratory during 2013-2016, seven parasitoid species were found to be primary and solitary, attacking larval and pupal stages of the host weevil. Pteromalus sp. 2 is the dominant species and also is the most competitive among the seven parasitoids, which could considered to be a perspective biological control agent of O. steppensis. Yet, the current control of this pest by the local natural enemies in Xinjiang is still currently inefficient, even though in 2016 parasitism was about 36% on U. pumila in Urumqi, so the potential for a classical biological control program against it needs to be further investigated, including an assessment of its parasitoids and other natural enemies in the native range of O. steppensis. The presented information on the natural enemies of this weevil can be also important for a potential classical biological control program against it in North America (Canada and USA), where it is a highly damaging and rapidly spreading invasive species.

  16. Transmitted drug resistance among antiretroviral-naive patients with established HIV type 1 infection in Santo Domingo, Dominican Republic and review of the Latin American and Caribbean literature.

    Science.gov (United States)

    Myers, Julie E; Taylor, Barbara S; Rojas Fermín, Rita A; Reyes, Emily Virginia; Vaughan, Catherine; José, Lina; Javier, Carmen; Franco Estévez, Ramona; Donastorg Cabral, Yeycy; Batista, Arelis; Lie, Yolanda; Coakley, Eoin; Hammer, Scott M; Brudney, Karen

    2012-07-01

    Emergence of HIV resistance is a concerning consequence of global scale-up of antiretroviral therapy (ART). To date, there is no published information about HIV resistance from the Dominican Republic. The study's aim was to determine the prevalence of transmitted drug resistance (TDR) to reverse transcriptase and protease inhibitors in a sample of chronically HIV-1-infected patients in one clinic in Santo Domingo. The data are presented in the context of a review of the TDR literature from Latin America and the Caribbean. Genotype testing was successfully performed on 103 treatment-naive adults planning to initiate antiretroviral therapy; the World Health Organization (WHO) list of surveillance drug resistance mutations (SDRM) was used to determine the presence of TDR mutations. WHO SDRM were identified in eight patients (7.8%); none had received sdNVP. There were no significant differences in epidemiologic or clinical variables between those with or without WHO SDRM. The prevalence of WHO SDRM was 1.0% and 6.8% for nucleoside reverse transcriptase inhibitors and nonnucleoside reverse transcriptase inhibitors, respectively. No WHO SDRMs for protease inhibitors were identified. Among 12 studies of TDR in the region with a sample size of at least 100 subjects, the reported prevalence of SDRM ranged from 2.8% to 8.1%. The most commonly identified SDRM was K103N. This information adds to our understanding of the epidemiology of TDR in the region and the possible role such mutations could play in undermining first-line treatment. Ongoing surveillance is clearly needed to better understand the TDR phenomenon in the Caribbean.

  17. Emergence and epidemiology of Cucurbit yellow stunting disorder virus in the American Desert Southwest, and development of host plant resistance in melon.

    Science.gov (United States)

    Wintermantel, William M; Gilbertson, Robert L; Natwick, Eric T; McCreight, James D

    2017-09-15

    Cucurbit yellow stunting disorder virus (CYSDV), emerged in the Sonoran Desert region of the southwestern USA in 2006 and has become well established. Symptoms induced by CYSDV infection include a striking interveinal chlorosis or yellowing and reduced yield and quality. The virus is transmitted by Bemisia tabaci, and the cryptic species MEAM1 has been present in the region since the early 1990s. CYSDV has now become the most economically important of the viruses affecting cucurbit production in the southwestern US. Here, we present a review of recent studies on CYSDV in the southwestern US, with implications for management of this virus throughout the world. Field surveys have established that CYSDV results in late-season infection of spring melon crops with limited economic impact; however, all summer and fall cucurbits become infected shortly after emergence due to high B. tabaci populations and abundant sources of inoculum. Studies have also demonstrated that CYSDV has an extensive host range among crops and weeds prevalent in the region. Recent studies demonstrated considerable variation in virus accumulation and transmission rates among the host plants evaluated as potential reservoirs. Cucurbit hosts had the highest CYSDV titers, were efficient sources for virus acquisition, and showed a positive correlation between titer in source plants and transmission to cucurbit plants. Non-cucurbit hosts had significantly lower CYSDV titers and varied in their capacity to serve as sources for transmission. Experiments demonstrated that multiple factors influence the efficiency with which a host plant species will be a reservoir for vector transmission of CYSDV to crops. Melon PI 313970 was identified as a new source of host plant resistance to CYSDV, in addition to the previously identified TGR 1551 (=PI 482420) and TGR 1937 (=PI 482431). Potential new sources of CYSDV resistance were identified by field screening of ca. 500 melon accessions with naturally occurring

  18. Haitian Americans.

    Science.gov (United States)

    Catanese, Anthony V.

    1998-01-01

    Uses 1990 U.S. Census data to show the changing demographic profile of Haitian Americans. Haitian Americans are likely to live along the Atlantic seaboard and to have relatively low, although not the lowest, incomes. However, the demographic mosaic of Haitian Americans is diverse, showing the effects of Haitian national and ethnic history. (SLD)

  19. The Effect of Dietary Glycemic Properties on Markers of Inflammation, Insulin Resistance, and Body Composition in Postmenopausal American Women: An Ancillary Study from a Multicenter Protein Supplementation Trial

    Directory of Open Access Journals (Sweden)

    Violeta Stojkovic

    2017-05-01

    Full Text Available Controversy exists as to whether high glycemic index/glycemic load (GI/GL diets increase the risk of chronic inflammation, which has been postulated as a pathogenic intermediary between such diets and age-related alterations in body composition and insulin resistance. We conducted an ancillary study to a randomized, double-blind trial comparing the effects of a whey protein supplement (PRO, n = 38 and a maltodextrin supplement (CHO, n = 46 on bone density to evaluate the impact of a calibrated increase in GI/GL on inflammation, insulin resistance, and body composition in a healthy aging population. Markers of inflammation, HOMA, body composition, and GI/GL (estimated from 3-day food records were assessed at baseline and 18 months. By 18 months, the GL in the CHO group increased by 34%, 88.4 ± 5.2 → 118.5 ± 4.9 and did not change in the PRO group, 86.5 ± 4.1 → 82.0 ± 3.6 (p < 0.0001. Despite this change there were no differences in serum CRP, IL-6, or HOMA at 18 months between the two groups, nor were there significant associations between GL and inflammatory markers. However, trunk lean mass (p = 0.0375 and total lean mass (p = 0.038 were higher in the PRO group compared to the CHO group at 18 months There were also significant associations for GL and change in total fat mass (r = 0.3, p = 0.01, change in BMI (r = 0.3, p = 0.005, and change in the lean-to-fat mass ratio (r = −0.3, p = 0.002. Our data suggest that as dietary GL increases within the moderate range, there is no detectable change in markers of inflammation or insulin resistance, despite which there is a negative effect on body composition.

  20. The antiplasmodium effects of a traditional South American remedy: Zanthoxylum chiloperone var. angustifolium against chloroquine resistant and chloroquine sensitive strains of Plasmodium falciparum

    Directory of Open Access Journals (Sweden)

    Gerardo Cebrian-Torrejon

    2011-06-01

    Full Text Available Zanthoxylum chiloperone var. angustifolium Engl., Rutaceae, is used in traditional medicine to treat fungal and protozoal infections in the central area of South America. Considering the increasing resistance of Plasmodium falciparum in malarial ridden areas, we explored the anti-plasmodial effects of three compounds isolated from Z. chiloperone. The pyranocoumarin transavicennol and the canthinone alkaloids, canthin-6-one and 5-methoxycanthin-6-one, were found to have IC50 on chloroquine/mefloquine resistant and sensitive strains of P. falciparum of 0.5-2.7, 2.0-5.3 and 5.1-10.4 ƒÊg/mL, respectively. Moreover, the formation of heme adducts by these compounds is described by a novel alternative method based on MS-CID methods. The alkylamide sanshool was also identified, for first time in this plant, in the dichloromethanic and ethanolic extracts and the extracts were found to be notably non-toxic and displayed good anti-plasmodial effects.

  1. Multi-scale gyrokinetic simulations of an Alcator C-Mod, ELM-y H-mode plasma

    Science.gov (United States)

    Howard, N. T.; Holland, C.; White, A. E.; Greenwald, M.; Rodriguez-Fernandez, P.; Candy, J.; Creely, A. J.

    2018-01-01

    High fidelity, multi-scale gyrokinetic simulations capable of capturing both ion ({k}θ {ρ }s∼ { O }(1.0)) and electron-scale ({k}θ {ρ }e∼ { O }(1.0)) turbulence were performed in the core of an Alcator C-Mod ELM-y H-mode discharge which exhibits reactor-relevant characteristics. These simulations, performed with all experimental inputs and realistic ion to electron mass ratio ({({m}i/{m}e)}1/2=60.0) provide insight into the physics fidelity that may be needed for accurate simulation of the core of fusion reactor discharges. Three multi-scale simulations and series of separate ion and electron-scale simulations performed using the GYRO code (Candy and Waltz 2003 J. Comput. Phys. 186 545) are presented. As with earlier multi-scale results in L-mode conditions (Howard et al 2016 Nucl. Fusion 56 014004), both ion and multi-scale simulations results are compared with experimentally inferred ion and electron heat fluxes, as well as the measured values of electron incremental thermal diffusivities—indicative of the experimental electron temperature profile stiffness. Consistent with the L-mode results, cross-scale coupling is found to play an important role in the simulation of these H-mode conditions. Extremely stiff ion-scale transport is observed in these high-performance conditions which is shown to likely play and important role in the reproduction of measurements of perturbative transport. These results provide important insight into the role of multi-scale plasma turbulence in the core of reactor-relevant plasmas and establish important constraints on the the fidelity of models needed for predictive simulations.

  2. Micropropagation and germplasm conservation of Central Park Splendor Chinese elm (Ulmus parvifolia Jacq. 'A/Ross Central Park') trees.

    Science.gov (United States)

    Thakur, R C; Karnosky, D F

    2007-08-01

    Micropropagation offers opportunities to propagate, preserve and ship tree germplasm. It also reduces the risk of moving pathogens and insects with the germplasm due to built-in pathogen detection capabilities of aseptic cultures. For the past few decades, our laboratory has been involved in a project to preserve and restore a large, cold hardy, and historically important Chinese elm (Ulmus parvifolia Jacq. 'A/Ross Central Park') tree. Here we present three simple and efficient systems for its micropropagation, germplasm conservation and distribution: (1) in vitro plant formation from meristematic nodules (MNs), (2) plantlet generation from axillary buds, and (3) in vitro rooting of micro-cuttings from 20-years-old hedged stock plants. Newly flushed nodal segments were used as explants. WPM with 0.5 mg/l BA was found to be the best medium for meristematic shoot development and WPM supplemented with 2.0 mg/l 4-CPPU and 0.5 mg/l TDZ was best for meristematic nodule formation. Rhizogenesis of regenerants and micro-cuttings was best achieved on WPM with 1.0 mg/l NAA and 2% sucrose. Rooted plants were readily acclimatized to the greenhouse ambient environment and continued to grow well under greenhouse conditions. The survival rate of acclimatized plantlets under ex vitro conditions was 100% after 4 weeks. Plants looked healthy with no visually detectable phenotypic variation based on observation of about 1,000 plants. Cycling of shoot explants and MNs through repetitive cultures was effective in scaling-up propagules.

  3. A Hybrid DE-RGSO-ELM for Brain Tumor Tissue Categorization in 3D Magnetic Resonance Images

    Directory of Open Access Journals (Sweden)

    K. Kothavari

    2014-01-01

    Full Text Available Medical diagnostics, a technique used for visualizing the internal structures and functions of human body, serves as a scientific tool to assist physicians and involves direct use of digital imaging system analysis. In this scenario, identification of brain tumors is complex in the diagnostic process. Magnetic resonance imaging (MRI technique is noted to best assist tissue contrast for anatomical details and also carries out mechanisms for investigating the brain by functional imaging in tumor predictions. Considering 3D MRI model, analyzing the anatomy features and tissue characteristics of brain tumor is complex in nature. Henceforth, in this work, feature extraction is carried out by computing 3D gray-level cooccurence matrix (3D GLCM and run-length matrix (RLM and feature subselection for dimensionality reduction is performed with basic differential evolution (DE algorithm. Classification is performed using proposed extreme learning machine (ELM, with refined group search optimizer (RGSO technique, to select the best parameters for better simplification and training of the classifier for brain tissue and tumor characterization as white matter (WM, gray matter (GM, cerebrospinal fluid (CSF, and tumor. Extreme learning machine outperforms the standard binary linear SVM and BPN for medical image classifier and proves better in classifying healthy and tumor tissues. The comparison between the algorithms proves that the mean and standard deviation produced by volumetric feature extraction analysis are higher than the other approaches. The proposed work is designed for pathological brain tumor classification and for 3D MRI tumor image segmentation. The proposed approaches are applied for real time datasets and benchmark datasets taken from dataset repositories.

  4. Second-Line Hormonal Therapy for Men With Chemotherapy-Naïve, Castration-Resistant Prostate Cancer: American Society of Clinical Oncology Provisional Clinical Opinion.

    Science.gov (United States)

    Virgo, Katherine S; Basch, Ethan; Loblaw, D Andrew; Oliver, Thomas K; Rumble, R Bryan; Carducci, Michael A; Nordquist, Luke; Taplin, Mary-Ellen; Winquist, Eric; Singer, Eric A

    2017-06-10

    Purpose ASCO provisional clinical opinions (PCOs) offer direction to the ASCO membership after publication or presentation of potential practice-changing data. This PCO addresses second-line hormonal therapy for chemotherapy-naïve men with castration-resistant prostate cancer (CRPC) who range from being asymptomatic with only biochemical evidence of CRPC to having documented metastases but minimal symptoms. Clinical Context The treatment goal for CRPC is palliation. Despite resistance to initial androgen deprivation therapy, most men respond to second-line hormonal therapies. However, guidelines have neither addressed second-line hormonal therapy for nonmetastatic CRPC nor provided specific guidance with regard to the chemotherapy-naïve population. Recent Data Six phase III randomized controlled trials and expert consensus opinion inform this PCO. Provisional Clinical Opinion For men with CRPC, a castrate state should be maintained indefinitely. Second-line hormonal therapy (eg, antiandrogens, CYP17 inhibitors) may be considered in patients with nonmetastatic CRPC at high risk for metastatic disease (rapid prostate-specific antigen doubling time or velocity) but otherwise is not suggested. In patients with radiographic evidence of metastases and minimal symptoms, enzalutamide or abiraterone plus prednisone should be offered after discussion with patients about potential harms, benefits, costs, and patient preferences. Radium-223 and sipuleucel-T also are options. No evidence provides guidance about the optimal order of hormonal therapies for CRPC beyond second-line treatment. Prostate-specific antigen testing every 4 to 6 months is reasonable for men without metastases. Routine radiographic restaging generally is not suggested but can be considered for patients at risk for metastases or who exhibit symptoms or other evidence of progression. Additional information is available at www.asco.org/genitourinary-cancer-guidelines and www.asco.org/guidelineswiki .

  5. Experimental estimation of tungsten impurity sputtering due to Type i ELMs in JET-ITER-like wall using pedestal electron cyclotron emission and target Langmuir probe measurements

    Czech Academy of Sciences Publication Activity Database

    Guillemaut, C.; Jardin, A.; Horáček, Jan; Borodkina, I.; Autricque, A.; Arnoux, G.; Boom, J.; Brezinsek, S.; Coenen, J.W.; De La Luna, E.; Devaux, S.; Eich, T.; Harting, D.; Kirschner, A.; Lipschultz, B.; Matthews, G. F.; Meigs, A.; Moulton, D.; O'Mullane, M.; Stamp, M.

    T167, February (2016), s. 014005 ISSN 0031-8949. [International Conference on Plasma-Facing Materials and Components for Fusion Applications, PFMC 2015/15./. Aix-en-Provence, 18.05.2015-22.05.2015] R&D Projects: GA MŠk LG14002 EU Projects: European Commission(XE) 633053 - EUROfusion Institutional support: RVO:61389021 Keywords : tungsten sputtering * edge localized mode * magnetic confinement fusion * ITER * H-mode * ELMs * Langmuir Probes (LP) Subject RIV: BL - Plasma and Gas Discharge Physics OBOR OECD: 1.3 Physical sciences Impact factor: 1.280, year: 2016 http://iopscience.iop.org/issue/1402-4896/2016/T167

  6. A compound structure of ELM based on feature selection and parameter optimization using hybrid backtracking search algorithm for wind speed forecasting

    International Nuclear Information System (INIS)

    Zhang, Chu; Zhou, Jianzhong; Li, Chaoshun; Fu, Wenlong; Peng, Tian

    2017-01-01

    Highlights: • A novel hybrid approach is proposed for wind speed forecasting. • The variational mode decomposition (VMD) is optimized to decompose the original wind speed series. • The input matrix and parameters of ELM are optimized simultaneously by using a hybrid BSA. • Results show that OVMD-HBSA-ELM achieves better performance in terms of prediction accuracy. - Abstract: Reliable wind speed forecasting is essential for wind power integration in wind power generation system. The purpose of paper is to develop a novel hybrid model for short-term wind speed forecasting and demonstrates its efficiency. In the proposed model, a compound structure of extreme learning machine (ELM) based on feature selection and parameter optimization using hybrid backtracking search algorithm (HBSA) is employed as the predictor. The real-valued BSA (RBSA) is exploited to search for the optimal combination of weights and bias of ELM while the binary-valued BSA (BBSA) is exploited as a feature selection method applying on the candidate inputs predefined by partial autocorrelation function (PACF) values to reconstruct the input-matrix. Due to the volatility and randomness of wind speed signal, an optimized variational mode decomposition (OVMD) is employed to eliminate the redundant noises. The parameters of the proposed OVMD are determined according to the center frequencies of the decomposed modes and the residual evaluation index (REI). The wind speed signal is decomposed into a few modes via OVMD. The aggregation of the forecasting results of these modes constructs the final forecasting result of the proposed model. The proposed hybrid model has been applied on the mean half-hour wind speed observation data from two wind farms in Inner Mongolia, China and 10-min wind speed data from the Sotavento Galicia wind farm are studied as an additional case. Parallel experiments have been designed to compare with the proposed model. Results obtained from this study indicate that the

  7. Nonlinear fluid simulation of particle and heat fluxes during burst of ELMs on DIII-D with BOUT++  code

    Science.gov (United States)

    Xia, T. Y.; Xu, X. Q.

    2015-09-01

    In order to study the distribution and evolution of the transient particle and heat fluxes during edge-localized mode (ELM) bursts, a BOUT++  six-field two-fluid model based on the Braginskii equations with non-ideal physics effects is used to simulate pedestal collapse in divertor geometry. The profiles from the DIII-D H-mode discharge #144382 with fast target heat flux measurements are used as the initial conditions for the simulations. A flux-limited parallel thermal conduction is used with three values of the flux-limiting coefficient {αj} , free streaming model with {αj}=1 , sheath-limit with {αj}=0.05 , and one value in between. The studies show that a 20 times increase in {αj} leads to  ∼6 times increase in the heat flux amplitude to both the inner and outer targets, and the widths of the fluxes are also expanded. The sheath-limit model of flux-limiting coefficient is found to be the most appropriate one, which shows ELM sizes close to the measurements. The evolution of the density profile during the burst of ELMs of DIII-D discharge #144382 is simulated, and the collapse in width and depth of {{n}\\text{e}} are reproduced at different time steps. The growing process of the profiles for the heat flux at divertor targets during the burst of ELMs measured by IRTV (infrared television) is also reproduced by this model. The widths of heat fluxes towards targets are a little narrower, and the peak amplitudes are twice the measurements possibly due to the lack of a model of divertor radiation which can effectively reduce the heat fluxes. The magnetic flutter combined with parallel thermal conduction is found to be able to increase the total heat loss by around 33% since the magnetic flutter terms provide the additional conductive heat transport in the radial direction. The heat flux profile at both the inner and outer targets is obviously broadened by magnetic flutter. The lobe structures near the X-point at LFS are both broadened and elongated due

  8. American = Independent?

    Science.gov (United States)

    Markus, Hazel Rose

    2017-09-01

    U.S. American cultures and psyches reflect and promote independence. Devos and Banaji (2005) asked, does American equal White? This article asks, does American equal independent? The answer is that when compared to people in East Asian or South Asian contexts, people in American contexts tend to show an independent psychological signature-a sense of self as individual, separate, influencing others and the world, free from influence, and equal to, if not better than, others (Markus & Conner, 2013). Independence is a reasonable description of the selves of people in the White, middle-class American mainstream. Yet it is a less good characterization of the selves of the majority of Americans who are working-class and/or people of color. A cultural psychological approach reveals that much of North American psychology is still grounded in an independent model of the self and, as such, neglects social contexts and the psychologies of a majority of Americans. Given the prominence of independence in American ideas and institutions, the interdependent tendencies that arise from intersections of national culture with social class, race, and ethnicity go unrecognized and are often misunderstood and stigmatized. This unseen clash of independence and interdependence is a significant factor in many challenges, including those of education, employment, health, immigration, criminal justice, and political polarization.

  9. Sex pheromone chemistry and field trapping studies of the elm spanworm Ennomos subsignaria (Hübner) (Lepidoptera:Geometridae)

    Science.gov (United States)

    Ryall, Krista; Silk, Peter J.; Wu, Junping; Mayo, Peter; Lemay, Matthew A.; Magee, David

    2010-08-01

    The elm spanworm, Ennomos subsignaria (Hübner), occurs throughout Canada and the eastern United States and can be a destructive forest pest on a wide range of deciduous trees. Gas chromatography/mass spectrometry (GC/MS) and coupled gas chromatographic-electroantennographic detection (GC/EAD) analysis of pheromone gland extracts, in combination with chemical synthesis and field trapping studies have identified (2 S, 3 R)-2-(( Z)-oct-2'-enyl)-3-nonyl oxirane (hereafter Z6-9 S, 10 R-epoxy-19:H) as the female-produced sex pheromone. Significantly more male moths were captured between 1-100 μg loadings of this compound on red rubber septa in sticky traps compared to blank (unbaited) traps; catches then declined at higher dosages (500-1000 μg). The other isomeric enantiomer, (2 R, 3 S)-2-[( Z)-oct-2'-enyl]-3-nonyl oxirane ( Z6-9 R, 10 S-epoxy-19:H), at a 10-μg dosage did not elicit trap capture. The likely precursor to the active epoxide, ( Z, Z)-6, 9-nonadecadiene (( Z, Z)-6, 9-19:H), identified in virgin female sex pheromone glands, did not elicit trap capture either, and inhibited trap capture when combined with the active epoxide. Racemic 2-((Z)-oct-2'-enyl)-3-nonyl oxirane showed no significant difference in trap capture compared with Z6-9 S, 10 R-epoxy-19:H, indicating that the opposite enantiomer was not antagonistic. The addition of the EAD-active diene epoxide enantiomers (2 S, 3 R)-2-[( Z, Z)-octa-2', 5'-dienyl]-3-nonyl oxirane or (2 R, 3 S)-2-[( Z, Z)-octa-2', 5'-dienyl]-3-nonyl oxirane in admixture with Z6-9 S, 10 R-epoxy-19:H (at 10% of the latter) did not enhance or decrease trap capture compared to Z6-9 S, 10 R-epoxy-19:H oxirane alone, so they are not likely pheromone components. This pheromone, impregnated in rubber septa at less than 100-μg dosage, can now be used as a trap bait to develop detection and monitoring strategies for this insect.

  10. Elm leaves 'warned' by insect egg deposition reduce survival of hatching larvae by a shift in their quantitative leaf metabolite pattern.

    Science.gov (United States)

    Austel, Nadine; Eilers, Elisabeth J; Meiners, Torsten; Hilker, Monika

    2016-02-01

    Plants may take insect eggs on their leaves as a warning of future herbivory and intensify their defence against feeding larvae. Responsible agents are, however, largely unknown, and little knowledge is available on this phenomenon in perennial plants. We investigated how egg deposition affects the anti-herbivore defence of elm against the multivoltine elm leaf beetle. Prior egg deposition caused changes in the quality of feeding-damaged leaves that resulted in increased larval mortality and reduced reproductive capacity of the herbivore by harming especially female larvae. Chemical analyses of primary and secondary leaf metabolites in feeding-damaged, egg-free (F) and feeding-damaged, egg-deposited (EF)-leaves revealed only small differences in concentrations when comparing metabolites singly. However, a pattern-focused analysis showed clearly separable patterns of (F) and (EF)-leaves because of concentration differences in especially nitrogen and phenolics, of which robinin was consumed in greater amounts by larvae on (EF) than on (F)-leaves. Our study shows that insect egg deposition mediates a shift in the quantitative nutritional pattern of feeding-damaged leaves, and thus might limit the herbivore's population growth by reducing the number of especially female herbivores. This may be a strategy that pays off in a long run particularly in perennial plants against multivoltine herbivores. © 2015 John Wiley & Sons Ltd.

  11. African American Educational Leadership in the School Superintendency

    Science.gov (United States)

    Smith, Eva C.

    2013-01-01

    African American educational leadership has long been part of American education and African American activism to resist oppression. However, the field of educational leadership has rarely included the contributions of African American leaders, particularly women leaders, into mainstream leadership theory and practices. This omission is difficult…

  12. Somatic embryogenesis in elm.

    Science.gov (United States)

    Corredoira, E; Vieitez, A M; Ballester, A

    2002-05-01

    We show that isolated zygotic embryos of Ulmus minor and U. glabra can produce embryogenic cultures provided they are isolated from immature seeds before storage proteins begin to accumulate. Rates of somatic embryogenesis were highest among zygotic embryos collected 6 weeks post-anthesis when they were at the midcotyledonary stage, were about 5 mm long and had a fresh weight of approx. 10 mg. At this time, induction was even possible in Murashige and Skoog basal medium with no plant growth regulators, but addition of 2,4-dichlorophenoxyacetic acid was necessary at earlier stages of zygotic development. In medium supplemented with benzyladenine (BA) only, no embryogenic induction was observed. The formation of callus was an essential step not only for the induction of embryogenic masses, but also for the maintenance of embryogenic competence through successive subculture of callus on induction media supplemented with 0.1 mg l(-1) BA. Nine embryogenic U. minor lines and 24 U. glabra lines have been maintained in this way for 3 years. However, conversion into plantlets has occurred only rarely.

  13. American Connections

    DEFF Research Database (Denmark)

    Petersen, Anne Ring

    2015-01-01

    The Danish artist Thomas Bang spent his early years in the USA. The works he created in this formative period were thus profoundly shaped by the contemporary movements in American art of the 1960s and 1970s when sculpture, or to be more precise, three-dimensional work became a hotbed of expansive...... experiments. This article traces how Bang made a radical move from painting to sculpture, which was characteristic of that time, and how he developed his artistic idiom by taking an active part in some of the seminal new departures in American art, in particular process art and post-minimalism. By leaping...... to the lasting impact of Bang's American period, which remains the key to understanding his works....

  14. Development of a double plasma gun device for investigation of effects of vapor shielding on erosion of PFC materials under ELM-like pulsed plasma bombardment

    Science.gov (United States)

    Sakuma, I.; Iwamoto, D.; Kitagawa, Y.; Kikuchi, Y.; Fukumoto, N.; Nagata, M.

    2012-10-01

    It is considered that thermal transient events such as type I edge localized modes (ELMs) could limit the lifetime of plasma-facing components (PFCs) in ITER. We have investigated surface damage of tungsten (W) materials under transient heat and particle loads by using a magnetized coaxial plasma gun (MCPG) device at University of Hyogo. The capacitor bank energy for the plasma discharge is 144 kJ (2.88 mF, 10 kVmax). Surface melting of a W material was clearly observed at the energy density of ˜2 MJ/m2. It is known that surface melting and evaporation during a transient heat load could generate a vapor cloud layer in front of the target material [1]. Then, the subsequent erosion could be reduced by the vapor shielding effect. In this study, we introduce a new experiment using two MCPG devices (MCPG-1, 2) to understand vapor shielding effects of a W surface under ELM-like pulsed plasma bombardment. The capacitor bank energy of MCPG-2 is almost same as that of MCPG-1. The second plasmoid is applied with a variable delay time after the plasmoid produced by MCPG-1. Then, a vapor cloud layer could shield the second plasma load. To verify the vapor shielding effects, surface damage of a W material is investigated by changing the delay time. In the conference, the preliminary experimental results will be shown.[4pt] [1] A. Hassanein et al., J. Nucl. Mater. 390-391, pp. 777-780 (2009).

  15. American Illuminations

    DEFF Research Database (Denmark)

    Nye, David

    Illuminated fêtes and civic celebrations began in Renaissance Italy and spread through the courts of Europe. Their fireworks, torches, lamps, and special effects glorified the monarch, marked the birth of a prince, or celebrated military victory. Nineteenth-century Americans rejected such monarch......Illuminated fêtes and civic celebrations began in Renaissance Italy and spread through the courts of Europe. Their fireworks, torches, lamps, and special effects glorified the monarch, marked the birth of a prince, or celebrated military victory. Nineteenth-century Americans rejected...... such monarchial pomp and adapted spectacular lighting to their democratic, commercial culture. In American Illuminations, David Nye explains how they experimented with gas and electric light to create illuminated cityscapes far brighter and more dynamic than those of Europe, and how these illuminations became......, commercial lighting that defined distinct zones of light and glamorized the city’s White Ways, skyscrapers, bridges, department stores, theaters, and dance halls. Poor and blighted areas disappeared into the shadows. American illuminations also became integral parts of national political campaigns...

  16. Infinite resistive lattices

    NARCIS (Netherlands)

    Atkinson, D; van Steenwijk, F.J.

    The resistance between two arbitrary nodes in an infinite square lattice of:identical resistors is calculated, The method is generalized to infinite triangular and hexagonal lattices in two dimensions, and also to infinite cubic and hypercubic lattices in three and more dimensions. (C) 1999 American

  17. How Many Equivalent Resistances?

    Indian Academy of Sciences (India)

    http://www.prenhall.com/boylestad/. [3]. Antoni Amengual, The intriguing properties of the equivalent resistances of n equal resistors combined in series and in parallel, American Journal of Physics, Vol.68, No.2, pp.175–179, 2000. DOI: http://dx.doi.org/. 10.1119/1.19396. [4]. Neil J A Sloane (Ed.), The On-Line Encyclopedia ...

  18. 10.5937/SelSem1702055Z= Black poplar and European white elm at Veliko ratno ostrvo island: Example of good practices in a genepool conservation of woody species

    Directory of Open Access Journals (Sweden)

    Zoran Maksimović

    2017-01-01

    Full Text Available This paper gives an overview of the activities carried out in order to conserve the black poplar (Populus nigra L. and European white elm (Ulmus laevis Pall. genofond in the protected natural area 'Veliko ratno ostrvo', as well as the results after the completion of these activities. These studies proved to be necessary due to the fact that the presence of black poplar and european white elm trees in rytic forests on the territory of the Republic of Serbia in the last decades have been decreasing. In the total forests of Serbia, autochthonous poplar forests participate with only 0.5-1.0%, and the European white elm is present with less than 1% of the trees and classified in the category of rare/endangered species. Based on the research carried out in the past six years, 907 black poplar trees and 89 trees in the Veliko ratno ostrvo Island area were recorded. In populations of black poplar and European white elm there was a high degree of genetic variability at the level of morphological and molecular markers. Both populations were characterized as good candidates for in situ conservation method and accordingly, conservation areas were marked. The high presence of weeds and the absence of natural regeneration indicate the need for additional measures of ex situ conservation. For the purpose of ex situ conservation in autumn 2013th, a total of 770 European white elm seedlings originating from 14 mother trees were planted, and in the autumn of the next year, a total of 802 black poplar clones originating from 9 selected trees from this area. The executed and prescribed measures of in situ and ex situ conservation are in line with current planning documents and protection measures of this area. By implementing measures of ex situ conservation of black poplar and European white elm genofond to the Veliko ratno ostrvo Island, the area under genetic resources of these species has been increased and a new young population has been established that will

  19. The impact of brick (Agrochola circellaris Hufn. and owlet moths (Lepidoptera: Noctuidae on the health of seeds of field elms (Ulmus minor Mill. in the landscape parks of the Świętokrzyskie Province

    Directory of Open Access Journals (Sweden)

    Bąk-Badowska Jolanta

    2017-06-01

    Full Text Available In the period of 2012-2013, a research was conducted to investigate the insects damaging the seeds of field elm (Ulmus minor Mill.. The aim of the research was to specify the damages to field elm seeds caused mainly by the brick (Agrochola circellaris and to indicate the possible dependence between the number of damaged seeds by the caterpillars of this moth and stand density. The research was conducted in the areas of Cisów-Orłowiny Landscape Park (C-OLP and Nida Landscape Park (NLP in the Świętokrzyskie Province. In both parks, there were two test stands situated, each of which covered the material collected from the trees. The number of field elms ranged from four to six. Furthermore, a sample of 300 seeds were randomly collected from each tree. The elms in Cisów-Orłowiny Landscape Park were observed in full density stands (fully stocked stands; however, these trees in Nida Landscape Park were growing in loose density stands (under-stocked stands. In total, there were 12,000 seeds collected from 20 trees. The analysis of the collected research material demonstrated that 436 seeds from the field elms (Ulmus minor were damaged by the brick (Agrochola circellaris. It constituted 3.6% of the total number of collected samples (Table 1. In the seed samples collected from the test stands in Cisów-Orłowiny Landscape Park, the damages caused by the caterpillars of the brick moth ranged between 0.8% and 2.9%. In the case of seed samples collected from Nida Landscape Park, the damages caused by the caterpillars of the brick moth were greater and ranged between 4.1% and 6.5%. The percentage of undamaged seeds ranged between 94.4% in Cisów-Orłowiny Landscape Park and 84.7% in Nida Landscape Park, which constituted, on an average, 89.5% for both parks. The 6.8% of the seeds were also damaged by other insects. The results of the research showed the dependence between the number of field elm seeds damaged by the brick Agrochola circellaris and the

  20. Resistance-resistant antibiotics.

    Science.gov (United States)

    Oldfield, Eric; Feng, Xinxin

    2014-12-01

    New antibiotics are needed because drug resistance is increasing while the introduction of new antibiotics is decreasing. We discuss here six possible approaches to develop 'resistance-resistant' antibiotics. First, multitarget inhibitors in which a single compound inhibits more than one target may be easier to develop than conventional combination therapies with two new drugs. Second, inhibiting multiple targets in the same metabolic pathway is expected to be an effective strategy owing to synergy. Third, discovering multiple-target inhibitors should be possible by using sequential virtual screening. Fourth, repurposing existing drugs can lead to combinations of multitarget therapeutics. Fifth, targets need not be proteins. Sixth, inhibiting virulence factor formation and boosting innate immunity may also lead to decreased susceptibility to resistance. Although it is not possible to eliminate resistance, the approaches reviewed here offer several possibilities for reducing the effects of mutations and, in some cases, suggest that sensitivity to existing antibiotics may be restored in otherwise drug-resistant organisms. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. American Studies

    Directory of Open Access Journals (Sweden)

    V. O. Pechatnov

    2014-01-01

    Full Text Available The "Founding fathers" of American Studies at MGIMO are considered to be A.V. Efimov and L.I. Clove. Alexey Efimov - Corresponding Member of the USSR Academy of Sciences since 1938, Head of the Department of Modern and Contemporary History and Dean of the Historical School at the Moscow State University - one of the first professors of the Faculty of International Relations MGIMO. Efimov distinguished himself by a broad vision and scope of scientific interests. Back in 1934 he published a monograph "On the history of capitalism in the United States," which initiated a series of research culminating in the fundamental work "The United States. The path of capitalist development (pre-imperialist era". Alexey was not only a great scientist but also a great teacher, whose lectures was popular throughout Moscow. His lecture courses, given at the end of the 1940s at MGIMO, became the basis for the first post-war history textbooks USA - "Essays on the history of the United States." At least as colorful a figure was Professor Leo Izrailevich Zubok - a man of unusual destiny. As a teenager he emigrated to the United States with his parents, where he soon joined the American revolutionary movement in the 1920s and was forced to leave the country. He came to MGIMO being already an experienced scientists. His research interests were very wide: from the study of American foreign policy expansion to the history of the labor movement in the United States. Zubok's fundamental works still have not lost its scientific significance. He has successfully combined scientific work with teaching. Tutorials that are based on his lectures were very popular not only among students of MGIMO.

  2. Immunizations and African Americans

    Science.gov (United States)

    ... Data > Minority Population Profiles > Black/African American > Immunizations Immunizations and African Americans African American adults are less ... 19 to 35 months had comparable rates of immunization. African American women are as likely to have ...

  3. PineElm_SSRdb: a microsatellite marker database identified from genomic, chloroplast, mitochondrial and EST sequences of pineapple (Ananas comosus(L.) Merrill).

    Science.gov (United States)

    Chaudhary, Sakshi; Mishra, Bharat Kumar; Vivek, Thiruvettai; Magadum, Santoshkumar; Yasin, Jeshima Khan

    2016-01-01

    Simple Sequence Repeats or microsatellites are resourceful molecular genetic markers. There are only few reports of SSR identification and development in pineapple. Complete genome sequence of pineapple available in the public domain can be used to develop numerous novel SSRs. Therefore, an attempt was made to identify SSRs from genomic, chloroplast, mitochondrial and EST sequences of pineapple which will help in deciphering genetic makeup of its germplasm resources. A total of 359511 SSRs were identified in pineapple (356385 from genome sequence, 45 from chloroplast sequence, 249 in mitochondrial sequence and 2832 from EST sequences). The list of EST-SSR markers and their details are available in the database. PineElm_SSRdb is an open source database available for non-commercial academic purpose at http://app.bioelm.com/ with a mapping tool which can develop circular maps of selected marker set. This database will be of immense use to breeders, researchers and graduates working on Ananas spp. and to others working on cross-species transferability of markers, investigating diversity, mapping and DNA fingerprinting.

  4. AMERICAN EXCEPTIONALISM

    Directory of Open Access Journals (Sweden)

    Oana-Andreea Pirnuta

    2017-11-01

    Full Text Available In an interconnected world where foreign relations matter not only for resources or military alliances but also for cultural relationships, it is highly important to have a better understanding of the power relations among nations. The information carries certain meanings that have important outcomes thus defining the power of a given nation. Foreign policy is the channel through which global politics is exercised. International politics is a hierarchy of power being determined by important cultural, economic as well as geographical aspects. The reasons and strategies that are used in order to reach the outcomes in global politics represent the focus of the present paper. The United States has been the leader in international politics since the early 20th century due to its vast resources and wealth as well as its cultural output. America’s interest in preserving a democratic and free world has its foundation in the beliefs and values it stands for the aim of this paper is to question whether or not there is a concrete premise for the idea of American exceptionalism.

  5. A Regional Guidebook for Applying the Hydrogeomorphic Approach to the Functional Assessment of Forested Wetlands in Alluvial Valleys of East Texas

    Science.gov (United States)

    2010-10-01

    laurel oak (Q. laurifolia), Shumard oak (Q. shumardii), elms ( Ulmus sp.), sweetgum (Liquidambar styraciflua), southern magnolia (Magnolia...plant species as the low-gradient riverine subclass. However, species such as American elm ( Ulmus americana), slippery elm ( Ulmus rubra), winged elm... Ulmus alata), cedar elm ( Ulmus crassifolia), river birch, box-elder (Acer negundo), hawthorn (Crataegus spp.) and loblolly pine (Pinus taeda) can be

  6. Changes in the mitochondrial protein profile due to ROS eruption during ageing of elm (Ulmus pumila L.) seeds.

    Science.gov (United States)

    Li, Ying; Wang, Yu; Xue, Hua; Pritchard, Hugh W; Wang, Xiaofeng

    2017-05-01

    Reactive oxygen species (ROS)-related mitochondrial dysfunction is considered to play a vital role in seed deterioration. However, the detailed mechanisms remain largely unknown. To address this, a comparison of mitochondrial proteomes was performed, and we identified several proteins that changed in abundance with accompanying ROS eruption and mitochondrial aggregation and diffusion. These are involved in mitochondrial metabolisms, stress resistance, maintenance of structure and intracellular transport during seed aging. Reduction of ROS content by the mitochondrial-specific scavenger MitoTEMPO suppressed these changes, whereas pre-treatment of seeds with methyl viologen (MV) had the opposite effect. Furthermore, voltage-dependent anion channels (VDAC) were found to increase both in abundance and carbonylation level, accompanied by increased cytochrome c (cyt c) release from mitochondria to cytosol, indicating the profound effect of ROS and VDAC on mitochondria-dependent cell death. Carbonylation detection revealed the specific target proteins of oxidative modification in mitochondria during ageing. Notably, membrane proteins accounted for a large proportion of these targets. An in vitro assay demonstrated that the oxidative modification was concomitant with a change of VDAC function and a loss of activity in malate dehydrogenase. Our data suggested that ROS eruption induced alteration and modification of specific mitochondrial proteins that may be involved in the process of mitochondrial deterioration, which eventually led to loss of seed viability. Copyright © 2017. Published by Elsevier Masson SAS.

  7. Native Americans with Diabetes

    Science.gov (United States)

    ... Read the MMWR Science Clips Native Americans with Diabetes Better diabetes care can decrease kidney failure Language: ... between 1996 and 2013. Problem Kidney failure from diabetes was highest among Native Americans. Native Americans are ...

  8. Equivalent resistors of polyhedral resistive structures

    NARCIS (Netherlands)

    van Steenwijk, FJ

    The equivalent resistors of regular polyhedral resistive structures between any two of the vertices are calculated in terms of the characteristic properties of the structures. Some special cases are considered. (C) 1998 American Association of Physics Teachers.

  9. Elm Tree (Ulmus parvifolia) Bark Bioprocessed with Mycelia of Shiitake (Lentinus edodes) Mushrooms in Liquid Culture: Composition and Mechanism of Protection against Allergic Asthma in Mice.

    Science.gov (United States)

    Kim, Sung Phil; Lee, Sang Jong; Nam, Seok Hyun; Friedman, Mendel

    2016-02-03

    Mushrooms can break down complex plant materials into smaller, more digestible and bioactive compounds. The present study investigated the antiasthma effect of an Ulmus parvifolia bark extract bioprocessed in Lentinus edodes liquid mycelium culture (BPUBE) against allergic asthma in chicken egg ovalbumin (OVA)-sensitized/challenged mice. BPUBE suppressed total IgE release from U266B1 cells in a dose-dependent manner without cytotoxicity. Inhibitory activity of BPUBE against OVA-specific IgE secretion in bronchoalveolar lavage fluid (BALF) was observed in OVA-sensitized/challenged asthmatic mice. BPUBE also inhibited OVA-specific IgG and IgG1 secretion into serum from the allergic mice, suggesting the restoration of a Th2-biased immune reaction to a Th1/Th2-balanced status, as indicated by the Th1/Th2 as well as regulatory T cell (Treg) cytokine profile changes caused by BPUBE in serum or BALF. Inflammatory cell counts in BALF and lung histology showed that leukocytosis and eosinophilia induced by OVA-sensitization/challenge were inhibited by the oral administration of BPUBE. Amelioration of eosinophil infiltration near the trachea was associated with reduced eotaxin and vascular cell adhesion molecule-1 (VCAM-1) levels. Changes in proinflammatory mediator levels in BALF suggest that BPUBE decreased OVA-sensitization-induced elevation of leukotriene C4 (LTC4) and prostaglandin D2 (PGD2). The finding that asthma-associated biomarker levels of OVA-sensitized/challenged mice were much more inhibited with BPUBE treatment than NPUBE (not-bioprocessed Ulmus parvifolia extract) treatment suggested the production of new bioactive compounds by the mushroom mycelia that may be involved in enhancing the observed antiasthmatic properties. The possible relation of the composition determined by proximate analysis and GC/MS to observed bioactivity is discussed. The results suggest that the elm tree (Ulmus parvifolia) bark bioprocessed with mycelia of shiitake (Lentinus edodes

  10. Theorizing the Racial and Gendered Educational Experiences of Chicanas and Native American Women at the Ph.D. Level in Higher Education: "Testimonios" of Resistance, Defiance, Survival, and Hope

    Science.gov (United States)

    Cueva, Bert Maria

    2013-01-01

    This national case study examines the educational experiences of twenty-one women that self-identified as low-income or working-class Chicanas or Native American women pursuing professoriate degrees in the Humanities, Social Sciences, Forestry, and Education. The case study includes forty-two qualitative "testimonio" interviews that…

  11. Seleção para alto teor de acilaçúcares em genótipos de tomateiro e sua relação com a resistência ao ácaro vermelho (Tetranychus evansi e à traça (Tuta absoluta Selection towards high acylsugar levels in tomato genotypes and its relationship with resistance to spider mite (Tetranychus evansi and to the South American pinworm (Tuta absoluta

    Directory of Open Access Journals (Sweden)

    Guilherme Victor Nippes Pereira

    2008-06-01

    Lycopersicon pennellii (Correll D'Arcy accession LA-716, acylsugars exsudated by type IV glandular trichomes present in all aerial parts of the plant reportedly mediate resistance to arthropod pests. This paper intended to study the levels of resistance to two arthropod pests, the South American tomato pinworm (Tuta absoluta and spider mites (Tetranychus evansi in tomato genotypes selected solely on the basis of their foliar acylsugar contents. Eleven plants with contrasting acylsugar contents were selected from population F3BC2 derived from the interespecific cross Lycopersicon esculentum 'TOM-584'x Lycopersicon pennellii 'LA-716'. These genotypes were used in tests for resistance/ repellence to the arthropod pests, along with parental checks TOM-584 and LA-716. In Tetranychus spp. mite repellence tests, plants selected for high acylsugar contents behaved similarly to the resistant parent LA-716. Negative and significative correlations between acylsugar contents and distances travelled by the mites onto the leaflet surface indicated an association between the allelochemical and the levels of mite repellence. In the assay with the South American pinworm, these genotypes were evaluated for leaflet lesion type and overall plant damage. The high acylsugar genotypes had good levels of insect resistance, similar to those found in LA-716. In all the evaluation date, acylsugars levels were highly and negatively correlated with pinworm damage. The results indicated that selection for high acylsugar contents was effective in increasing the levels of arthropod resistance of tomato genotypes.

  12. Antimicrobial Resistance

    Science.gov (United States)

    ... least 10 countries (Australia, Austria, Canada, France, Japan, Norway, Slovenia, South Africa, Sweden and the United Kingdom ... plan Global report on surveillance Country situation analysis Policy to combat antimicrobial resistance More on antimicrobial resistance ...

  13. Drug Resistance

    Science.gov (United States)

    ... infected with a drug-resistant strain of HIV. Drug-resistance testing results are used to decide which HIV medicines to include in a person’s first HIV regimen. After treatment is started, drug-resistance testing is repeated if ...

  14. Antibiotic Resistance

    DEFF Research Database (Denmark)

    Munck, Christian

    of antimicrobial resistance: (1) adaptive mutations and (2) horizontal acquisition of resistance genes from antibiotic gene reservoirs. By studying the geno- and phenotypic changes of E. coli in response to single and drug-pair exposures, I uncover the evolutionary trajectories leading to adaptive resistance. I......Bacteria can avoid extinction during antimicrobial exposure by becoming resistant. They achieve this either via adaptive mutations or horizontally acquired resistance genes. If resistance emerges in clinical relevant species, it can lead to treatment failure and ultimately result in increasing...... morbidity and mortality as well as an increase in the cost of treatment. Understanding how bacteria respond to antibiotic exposure gives the foundations for a rational approach to counteract antimicrobial resistance. In the work presented in this thesis, I explore the two fundamental sources...

  15. Evaluation of two vaccine education interventions to improve pertussis vaccination among pregnant African American women: A randomized controlled trial.

    Science.gov (United States)

    Kriss, Jennifer L; Frew, Paula M; Cortes, Marielysse; Malik, Fauzia A; Chamberlain, Allison T; Seib, Katherine; Flowers, Lisa; Ault, Kevin A; Howards, Penelope P; Orenstein, Walter A; Omer, Saad B

    2017-03-13

    Vaccination coverage with tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine in pregnancy or immediately postpartum has been low. Limited data exist on rigorously evaluated interventions to increase maternal vaccination, including Tdap. Tailored messaging based on the Elaboration Likelihood Model (ELM) framework has been successful in improving uptake of some public health interventions. We evaluated the effect of two ELM-based vaccine educational interventions on Tdap vaccination among pregnant African American women, a group of women who tend to have lower vaccine uptake compared with other groups. We conducted a prospective randomized controlled trial to pilot test two interventions - an affective messaging video and a cognitive messaging iBook - among pregnant African American women recruited during routine prenatal care visits. We measured Tdap vaccination during the perinatal period (during pregnancy and immediately postpartum), reasons for non-vaccination, and intention to receive Tdap in the next pregnancy. Among the enrolled women (n=106), 90% completed follow-up. Tdap vaccination in the perinatal period was 18% in the control group; 50% in the iBook group (Risk Ratio [vs. control group]: 2.83; 95% CI, 1.26-6.37), and 29% in the video group (RR: 1.65; 95% CI, 0.66-4.09). From baseline to follow-up, women's reported intention to receive Tdap during the next pregnancy improved in all three groups. Among unvaccinated women, the most common reason reported for non-vaccination was lack of a recommendation for Tdap by the woman's physician. Education interventions that provide targeted information for pregnant women in an interactive manner may be useful to improve Tdap vaccination during the perinatal period. However, larger studies including multiple racial and ethnic groups are needed to evaluate robustness of our findings. clinicaltrials.gov Identifier: NCT01740310. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Camptothecin resistance

    DEFF Research Database (Denmark)

    Brangi, M; Litman, Thomas; Ciotti, M

    1999-01-01

    The mitoxantrone resistance (MXR) gene encodes a recently characterized ATP-binding cassette half-transporter that confers multidrug resistance. We studied resistance to the camptothecins in two sublines expressing high levels of MXR: S1-M1-80 cells derived from parental S1 colon cancer cells...... and MCF-7 AdVp3,000 isolated from parental MCF-7 breast cancer cells. Both cell lines were 400- to 1,000-fold more resistant to topotecan, 9-amino-20(S)-camptothecin, and the active metabolite of irinotecan, 7-ethyl-10-hydroxycamptothecin (SN-38), than their parental cell lines. The cell lines...... demonstrated much less resistance to camptothecin and to several camptothecin analogues. Reduced accumulation and energy-dependent efflux of topotecan was demonstrated by confocal microscopy. A significant reduction in cleavable complexes in the resistant cells could be observed after SN-38 treatment...

  17. American Macular Degeneration Foundation

    Science.gov (United States)

    ... Policy Disclaimer Contact Us Donate Store The American Macular Degeneration Foundation The American Macular Degeneration Foundation (AMDF) is ... Ed Asner Video Clip An Inspiring Her-story Macular Degeneration is the leading cause of vision loss, affecting ...

  18. American Society of Echocardiography

    Science.gov (United States)

    American Society of Echocardiography Join Ase Renew Member Portal Log In Membership Member Portal Log In Join ASE Renew Benefits Rates FASE – Fellow of the American Society of Echocardiography Member Referral Program FAQs Initiatives Advocacy Awards, Grants, ...

  19. Depression and African Americans

    Science.gov (United States)

    ... You are here Home » Depression And African Americans Depression And African Americans Not “Just the Blues” Clinical ... or spiritual communities. Commonly Asked Questions about Clinical Depression How do I get help for clinical depression? ...

  20. African Americans and Glaucoma

    Science.gov (United States)

    ... Americans are still unknown. However, research shows that African Americans are genetically more at risk for glaucoma, making early detection and treatment all the more important. In studies such as the Baltimore Eye Survey and the ...

  1. Chemical changes in Ulmus minor xylem tissue after salicylic acid or carvacrol treatments are associated with enhanced resistance to Ophiostoma novo-ulmi.

    Science.gov (United States)

    Martín, Juan A; Solla, Alejandro; García-Vallejo, María C; Gil, Luis

    2012-11-01

    Application of endogenous plant hormone salicylic acid (SA) or essential oil component carvacrol (CA) in elms enhances tree resistance to the Dutch elm disease pathogen, although the effect of these compounds on tree metabolism is unknown. The chemical changes induced by SA or CA treatments in Ulmus minor were studied through gas chromatography-mass spectrometry (GC-MS) analysis of xylem tissues. Treatments consisted of fortnightly irrigating seedlings with water, SA or CA at 600 mg L⁻¹. The chemical composition of the xylem tissues sampled from treated trees was significantly altered depending on the treatment type. SA treatment induced an accumulation of the sinapyl alcohol, a precursor of lignin and other phenylpropanoid-derived products. CA treatment induced an accumulation of the methyl esters of palmitic, linoleic and stearic acids. Both treatments resulted in early bud burst and SA significantly reduced sapwood radial growth, possibly as a consequence of a trade-off between tree growth and tree defence. The enhanced resistance provided by these treatments is discussed. Copyright © 2012 Elsevier Ltd. All rights reserved.

  2. Resistant Hypertension.

    Science.gov (United States)

    Doroszko, Adrian; Janus, Agnieszka; Szahidewicz-Krupska, Ewa; Mazur, Grzegorz; Derkacz, Arkadiusz

    2016-01-01

    Resistant hypertension is a severe medical condition which is estimated to appear in 9-18% of hypertensive patients. Due to higher cardiovascular risk, this disorder requires special diagnosis and treatment. The heterogeneous etiology, risk factors and comorbidities of resistant hypertension stand in need of sophisticated evaluation to confirm the diagnosis and select the best therapeutic options, which should consider lifestyle modifications as well as pharmacological and interventional treatment. After having excluded pseudohypertension, inappropriate blood pressure measurement and control as well as the white coat effect, suspicion of resistant hypertension requires an analysis of drugs which the hypertensive patient is treated with. According to one definition - ineffective treatment with 3 or more antihypertensive drugs including diuretics makes it possible to diagnose resistant hypertension. A multidrug therapy including angiotensin - converting enzyme inhibitors, angiotensin II receptor blockers, beta blockers, diuretics, long-acting calcium channel blockers and mineralocorticoid receptor antagonists has been demonstrated to be effective in resistant hypertension treatment. Nevertheless, optional, innovative therapies, e.g. a renal denervation or baroreflex activation, may create a novel pathway of blood pressure lowering procedures. The right diagnosis of this disease needs to eliminate the secondary causes of resistant hypertension e.g. obstructive sleep apnea, atherosclerosis and renal or hormonal disorders. This paper briefly summarizes the identification of the causes of resistant hypertension and therapeutic strategies, which may contribute to the proper diagnosis and an improvement of the long term management of resistant hypertension.

  3. Managing Resistance.

    Science.gov (United States)

    Maag, John W.

    2000-01-01

    This article presents some considerations and ideas for managing students' resistance. They are organized around four topics: the impact of context on behavior, the importance of being comprehensive and nonrestrictive in behavior, the adaptive function of resistant behavior, and the benefit of joining children in their frame of reference.…

  4. Unlearning American Patriotism

    Science.gov (United States)

    Miller, Richard W.

    2007-01-01

    Immoral excesses of American foreign policy are so severe and so deep-rooted that American patriotism is now a moral burden. This love, which pulls toward amnesia, wishful thinking and inattention to urgent foreign interests, should be replaced by commitment to a global social movement that seeks to hem in the American empire. Teachers can advance…

  5. The American Dream

    OpenAIRE

    Nielsen, Kristian

    2014-01-01

    This thesis deals with the deceptive nature of The American Dream and its place in American culture in the first six decades of the 20th century, namely in the three quintessential novels The Great Gatsby, The Grapes of Wrath and Fear and Loathing in Las Vegas. With the aid of Jim Cullen's The American Dream – A short history of an idea that shaped a nation and Lawrence Samuel's The American Dream – A cultural history the different types of American Dreams are investigated, as well as how the...

  6. Antimicrobial Resistance

    Science.gov (United States)

    ... life-threatening infections – to a last resort treatment (carbapenem antibiotics) has spread to all regions of the ... unit patients. In some countries, because of resistance, carbapenem antibiotics do not work in more than half ...

  7. Evidence of Zonal-Flow-Driven Limit-Cycle Oscillations during L-H Transition and at H-mode Pedestal of a New Small-ELM Regime in EAST

    DEFF Research Database (Denmark)

    Xu, G.; Wang, H.; Guo, H.

    Small-amplitude edge localized oscillations have been observed, for the first time, in EAST preceding the L-H transition at marginal input power, which manifest themselves as dithering in the divertor D signals at a frequency under 4 kHz, much lower than the GAM frequency. Detailed measurements...... providing a direct evidence of the zonal flows for the L-H transition at marginal input power. Furthermore, near the transition threshold sawtooth heat pulses appear to periodically enhance the dithering, finally triggering the L-H transition after a big sawtooth crash. The zonal flow induced limit...... link between them. A novel predator-prey model, incorporating the evolution of zonal flows, pressure gradient and turbulences at two different frequency ranges, has been developed and successfully reproduced the key features of this newly observed small-ELM regime....

  8. Further insights into the components of resistance to Ophiostoma novo-ulmi in Ulmus minor: hydraulic conductance, stomatal sensitivity and bark dehydration.

    Science.gov (United States)

    Pita, Pilar; Rodríguez-Calcerrada, Jesús; Medel, David; Gil, Luis

    2018-02-01

    Dutch elm disease (DED) is a vascular disease that has killed over 1 billion elm trees. The pathogen spreads throughout the xylem network triggering vessel blockage, which results in water stress, tissue dehydration and extensive leaf wilting in susceptible genotypes. We investigated the differences between four Ulmus minor Mill. clones of contrasting susceptibility to Ophiostoma novo-ulmi Brasier regarding morphological, anatomical and physiological traits affecting water transport, in order to gain a better understanding of the mechanisms underlying DED susceptibility. We analyzed the differential response to water shortage and increased air vapor pressure deficit (VPD) to investigate whether resistance to water stress might be related to DED tolerance. Sixteen plants per clone, aged 2 years, were grown inside a greenhouse under differential watering. Stomatal conductance was measured under ambient and increased VPD. Growth, bark water content and stem hydraulic and anatomical parameters were measured 22 days after starting differential watering. Vessel lumen area, lumen fraction and hydraulic conductance were highest in susceptible clones. Stomatal conductance was lowest under low VPD and decreased faster under increased VPD in resistant clones. We found a negative relationship between the decrease in stomatal conductance at increased VPD and specific hydraulic conductance, revealing a narrower hydraulic margin for sustaining transpiration in resistant clones. The effect of water shortage was greater on radial stem growth than on leaf area, which could be explained through an extensive use of capacitance water to buffer xylem water potential. Water shortage reduced stomatal conductance and vessel lumen area. Bark water content under conditions of water shortage only decreased in susceptible clones. Higher hydraulic constraints to sap flow in resistant clones may determine higher stomatal sensitivity to VPD and so contribute to DED resistance by limiting pathogen

  9. Evaluation of North American isolates of Soybean mosaic virus for gain of virulence on Rsv-genotype soybeans with special emphasis on resistance-breaking determinants on Rsv4.

    Science.gov (United States)

    Khatabi, B; Fajolu, O L; Wen, R-H; Hajimorad, M R

    2012-12-01

    Resistance to Soybean mosaic virus (SMV) in soybean is conferred by three dominant genes: Rsv1, Rsv3 and Rsv4. Over the years, scientists in the USA have utilized a set of standard pathotypes, SMV-G1 to SMV-G7, to study interaction with Rsv-genotype soybeans. However, these pathotypes were isolated from a collection of imported soybean germplasm over 30 years ago. In this study, 35 SMV field isolates collected in recent years from 11 states were evaluated for gain of virulence on soybean genotypes containing individual Rsv genes. All isolates were avirulent on L78-379 (Rsv1), whereas 19 were virulent on L29 (Rsv3). On PI88788 (Rsv4), 14 of 15 isolates tested were virulent; however, only one was capable of systemically infecting all of the inoculated V94-5152 (Rsv4). Nevertheless, virulent variants from 11 other field isolates were rapidly selected on initial inoculation onto V94-5152 (Rsv4). The P3 cistrons of the original isolates and their variants on Rsv4-genotype soybeans were sequenced. Analysis showed that virulence on PI88788 (Rsv4) was not associated, in general, with selection of any new amino acid, whereas Q1033K and G1054R substitutions were consistently selected on V94-5152 (Rsv4). The role of Q1033K and G1054R substitutions, individually or in combination, in virulence on V94-5152 (Rsv4) was confirmed on reconstruction in the P3 cistron of avirulent SMV-N, followed by biolistic inoculation. Collectively, our data demonstrate that SMV has evolved virulence towards Rsv3 and Rsv4, but not Rsv1, in the USA. Furthermore, they confirm that SMV virulence determinants on V94-5152 (Rsv4) reside on P3. © 2012 THE AUTHORS. MOLECULAR PLANT PATHOLOGY © 2012 BSPP AND BLACKWELL PUBLISHING LTD.

  10. Rediscovering Interwar American Theorists

    Science.gov (United States)

    2017-05-25

    common perception, the early 20th century was a period of significant intellectual development in American military theory. Organizational changes in...Rediscovering Interwar American Theorists A Monograph by MAJ Russell McKelvey United States Army School of Advanced Military Studies United...DATES COVERED (From - To) JUN 2016 – MAY 2017 4. TITLE AND SUBTITLE Rediscovering Interwar American Theorists 5a. CONTRACT NUMBER 5b. GRANT NUMBER

  11. Acylsugars in tomato leaflets confer resistance to the South American tomato pinworm, Tuta absoluta Meyr Acilaçúcares presentes em folíolos de tomateiro conferem resistência à traça do tomateiro, Tuta absoluta Meyr

    Directory of Open Access Journals (Sweden)

    Juliano Tadeu Vilela de Resende

    2006-02-01

    Full Text Available Acylsugars present in the accession 'LA716' of Lycopersicon pennellii play an important role in the resistance to Tuta absoluta. This paper investigates the possible association between the resistance to T. absoluta and the acylsugar contents in F2 and F2BC1 tomato plants derived from the interspecific crossing between L. esculentum 'TOM-584' and L. pennellii 'LA716'. From the F2 population, four high acylsugars and one low acylsugars plants were selected and tested for Tuta absoluta resistance along with parental lines TOM-584 and LA-716, and with the checks TOM-600 (high 2-tridecanone line with resistance to T. absoluta and TOM-556 (low acylsugar line. The genotypes were tested under natural field infestation and were evaluated for overall plant damage, leaflet lesion type and percent of attacked leaflet. Four plants from F2BC1 [=(Lycopersicon esculentum 'TOM-584' ´ F2] were selected for high acylsugars and two for low acylsugars, and tested in greenhouse cages infested with T. absoluta. These genotypes were evaluated with the parental lines and the checks for oviposition ten days after infestation, and for leaflet lesion type and overall plant damage at four different dates. The F2 genotypes BPX-370Bpl#25, BPX-370Bpl#30 and BPX-370Bpl#79, the F2BC1 genotypes BPX-370B pl#30-380 and BPX-370B pl#30-271 and the wild accession LA716 had good levels of resistance to Tuta absoluta. The resistance level increased with longer exposition time to the acylsugars, both in the field and in the cage tests. Acylsugar contents seemed to be highly and negatively correlated with the traits related to the pinworm resistance.Os acilaçúcares presentes no acesso 'LA716' de Lycopersicon pennellii exercem um papel importante na resistência a Tuta absoluta. Foi avaliada a associação entre níveis de resistência à T. absoluta e o nível de acilaçúcares em plantas das gerações F2 e F2RC1 do cruzamento interespecífico L. esculentum 'TOM-584' ´ L. pennellii

  12. Resident resistance.

    Science.gov (United States)

    Price, J L; Cleary, B

    1999-01-01

    Clearly, faculty must work hard with residents to explore the nature of their resistance to a program's learning and growth opportunities. Initial steps to a deeper, more effective, and longer-lasting change process must be pursued. If resident resistance is mishandled or misunderstood, then learning and professional growth may be sidetracked and the purposes of residency training defeated. Listening to the whole person of the resident and avoiding the trap of getting caught up in merely responding to select resident behaviors that irritate us is critical. Every faculty member in the family practice residency program must recognize resistance as a form of defense that cannot immediately be torn down or taken away. Resident defenses have important purposes to play in stress reduction even if they are not always healthy. Residents, especially interns, use resistance to avoid a deeper and more truthful look at themselves as physicians. A family practice residency program that sees whole persons in their residents and that respects resident defenses will effectively manage the stress and disharmony inherent to the resistant resident.

  13. Anticoagulant Resistance

    DEFF Research Database (Denmark)

    Heiberg, Ann-Charlotte

    Although sewer rat control is carried out in more than 80 % of all Danish municipalities, with usage of large amounts of anticoagulant rodenticides, knowledge on anticoagulant resistance among rats living in the sewers is limited. As rat problems in urban areas are believed to be related to sewer...... problems (70-90 % in UK and DK) unawareness of resistance amongst these populations of Brown rats may constitute a future control problem and knowledge on this issue has become crucial. Rats were captured in sewers from seven different locations in the suburban area of Copenhagen. Locations was chosen...... to represent different sewer rat management strategies i) no anticoagulants for approx. 20 years ii) no anticoagulants for the last 5 years and iii) continuous control for many years. Animals were tested for resistance to bromadiolone by Blood-Clotting Response test, as bromadiolone is the most frequently used...

  14. Reducing Resistance

    DEFF Research Database (Denmark)

    Lindell, Johanna

    care may influence decisions on antibiotic use. Based on video-and audio recordings of physician-patient consultations it is investigated how treatment recommendations are presented, can be changed, are forecast and explained, and finally, how they seemingly meet resistance and how this resistance......Antibiotic resistance is a growing public health problem both nationally and internationally, and efficient strategies are needed to reduce unnecessary use. This dissertation presents four research studies, which examine how communication between general practitioners and patients in Danish primary...... is responded to.The first study in the dissertation suggests that treatment recommendations on antibiotics are often done in a way that encourages patient acceptance. In extension of this, the second study of the dissertation examines a case, where acceptance of such a recommendation is changed into a shared...

  15. American Indian Influence on the American Pharmacopeia.

    Science.gov (United States)

    Vogel, Virgil J.

    The first U.S. Pharmacopeia, issued in 1820, listed 296 substances of animal, mineral, or vegetable origin in its primary and secondary lists. Of these 130, nearly all of vegetable origin, represented drugs used by American Indians. The number grew at each decennial revision during the 19th century, though some drugs were listed only for a decade.…

  16. Resistant and Refractory Hypertension: Antihypertensive Treatment Resistance vs Treatment Failure

    Science.gov (United States)

    Siddiqui, Mohammed; Dudenbostel, Tanja; Calhoun, David A.

    2017-01-01

    Resistant or difficult to treat hypertension is defined as high blood pressure that remains uncontrolled with 3 or more different antihypertensive medications, including a diuretic. Recent definitions also include controlled blood pressure with use of 4 or more medications as also being resistant to treatment. Recently, refractory hypertension, an extreme phenotype of antihypertensive treatment failure has been defined as hypertension uncontrolled with use of 5 or more antihypertensive agents, including a long-acting thiazide diuretic and a mineralocorticoid receptor antagonist. Patients with resistant vs refractory hypertension share similar characteristics and comorbidities, including obesity, African American race, female sex, diabetes, coronary heart disease, chronic kidney disease, and obstructive sleep apnea. Patients with refractory vs resistant hypertension tend to be younger and are more likely to have been diagnosed with congestive heart failure. Refractory hypertension might also differ from resistant hypertension in terms of underlying cause. Preliminary evidence suggests that refractory hypertension is more likely to be neurogenic in etiology (ie, heightened sympathetic tone), vs a volume-dependent hypertension that is more characteristic of resistant hypertension in general. PMID:26514749

  17. American Studies in Transition

    DEFF Research Database (Denmark)

    Nye, David

    Papers first given at a conference the previous year in Fåborg, Denmark, with a dual focus on 20th century America and new methods in American Studies.......Papers first given at a conference the previous year in Fåborg, Denmark, with a dual focus on 20th century America and new methods in American Studies....

  18. African American Suicide

    Science.gov (United States)

    African American Suicide Fact Sheet Based on 2012 Data (2014) Overview • In 2012, 2,357 African Americans completed suicide in the U.S. Of these, 1,908 (80. ... rate of 9.23 per 100,000). The suicide rate for females was 1.99 per 100, ...

  19. Writing American Indian History

    Science.gov (United States)

    Noley, Grayson B.

    2008-01-01

    The purpose of this paper is to critique the manner in which history about American Indians has been written and propose a rationale for the rethinking of what we know about this subject. In particular, histories of education as regards the participation of American Indians is a subject that has been given scant attention over the years and when…

  20. Teaching American Indian Architecture.

    Science.gov (United States)

    Winchell, Dick

    1991-01-01

    Reviews "Native American Architecture," by Nabokov and Easton, an encyclopedic work that examines technology, climate, social structure, economics, religion, and history in relation to house design and the "meaning" of space among tribes of nine regions. Describes this book's use in a college course on Native American architecture. (SV)

  1. Resistance welding

    DEFF Research Database (Denmark)

    Bay, Niels; Zhang, Wenqi; Rasmussen, Mogens H.

    2003-01-01

    Resistance welding comprises not only the well known spot welding process but also more complex projection welding operations, where excessive plastic deformation of the weld point may occur. This enables the production of complex geometries and material combinations, which are often not possible...

  2. Drug resistance

    NARCIS (Netherlands)

    Gorter, J.A.; Potschka, H.; Noebels, J.L.; Avoli, M.; Rogawski, M.A.; Olsen, R.W.; Delgado-Escueta, A.V.

    2012-01-01

    Drug resistance remains to be one of the major challenges in epilepsy therapy. Identification of factors that contribute to therapeutic failure is crucial for future development of novel therapeutic strategies for difficult-to-treat epilepsies. Several clinical studies have shown that high seizure

  3. Genre Categorization in Contemporary British and US-American Novels

    OpenAIRE

    Ceia, Carlos

    2016-01-01

    In his article "Genre Categorization in Contemporary British and US-American Novels" Carlos Ceia discusses a certain type of resistance to genre categorization in many novels in contemporary literature. Many British and US-American contemporary novels show patterns in narrative creativity where novel-writing techniques are sometimes more important than the traditional subject matter driven work of fiction. Ceia reviews experimental/metafictional novels which do not show intent to fulfil an ae...

  4. Aging of residual surface resistance of superconducting lead cavities

    DEFF Research Database (Denmark)

    Danielsen, M.

    1972-01-01

    Measurements of the residual surface resistance of superconducting lead cavities as a function of time during a period of a month showed an oscillating variation. An explanation of the ageing curves is proposed. ©1972 The American Institute of Physics......Measurements of the residual surface resistance of superconducting lead cavities as a function of time during a period of a month showed an oscillating variation. An explanation of the ageing curves is proposed. ©1972 The American Institute of Physics...

  5. Lolita - the American nightmare

    OpenAIRE

    GRISELDA (ABAZAJ) DANGLLI

    2012-01-01

    This article deals with the analysis of Lolita seen through the lenses of the American society and norms of today. We will see that many observations of the American way of behaving and social norms still hold true even nowadays years after this novel was written. Nabokov, on the other hand, never accepted the fact that this novel probed into the very depths of American life and that his intentions were purely aesthetic. Nevertheless, the phenomenon of pedophilia, obvious in the book, is a po...

  6. American Studies in Romania

    Directory of Open Access Journals (Sweden)

    Ioana Luca

    2006-01-01

    Full Text Available American Studies at the University of BucharestThe idea of teaching American Studies and founding a program in American Studies was first voiced in the long meetings of faculty and students held at the University of Bucharest soon after the collapse of the communist regime. The proposal was one of many that reflected the spirit of reform and hope for radical changes at the outset of Romania’s transition to democracy. The absence of institutional structures other than English departments and t...

  7. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... video) Animation of Antimicrobial Resistance (text version) Arabic Translation of Animation of Antimicrobial Resistance Chinese Translation of Animation of Antimicrobial Resistance French Translation of ...

  8. Can vessel dimension explain tolerance toward fungal vascular wilt diseases in woody plants? Lessons from Dutch elm disease and esca disease in grapevine

    OpenAIRE

    Pouzoulet, Jérôme; Pivovaroff, Alexandria L.; Santiago, Louis S.; Rolshausen, Philippe E.

    2014-01-01

    This review illuminates key findings in our understanding of grapevine xylem resistance to fungal vascular wilt diseases. Grapevine (Vitis spp.) vascular diseases such as esca, botryosphaeria dieback, and eutypa dieback, are caused by a set of taxonomically unrelated ascomycete fungi. Fungal colonization of the vascular system leads to a decline of the plant host because of a loss of the xylem function and subsequent decrease in hydraulic conductivity. Fungal vascular pathogens use different ...

  9. Antibiotic Resistance

    DEFF Research Database (Denmark)

    Hansen, Malene Plejdrup; Hoffmann, Tammy C; McCullough, Amanda R

    2015-01-01

    Numerous opportunities are available in primary care for alleviating the crisis of increasing antibiotic resistance. Preventing patients from developing an acute respiratory infection (ARI) will obviate any need for antibiotic use downstream. Hygiene measures such as physical barriers and hand...... will greatly improve the use of antibiotics for ARIs. However, used in concert, combinations are likely to enable clinicians and health care systems to implement the strategies that will reduce antimicrobial resistance in the future....... antibiotic prescribing are a major factor in the prescribing for ARIs. Professional interventions with educational components are effective, although they have modest effects, and are expensive. GPs' perceptions - that mistakenly assume as a default that patients want antibiotics for their ARIs - are often...

  10. Antimicrobial resistance

    DEFF Research Database (Denmark)

    Llor, Carl; Bjerrum, Lars

    2014-01-01

    Antimicrobial resistance is a global public health challenge, which has accelerated by the overuse of antibiotics worldwide. Increased antimicrobial resistance is the cause of severe infections, complications, longer hospital stays and increased mortality. Overprescribing of antibiotics......-the-counter sale of antibiotics, the use of antimicrobial stewardship programmes, the active participation of clinicians in audits, the utilization of valid rapid point-of-care tests, the promotion of delayed antibiotic prescribing strategies, the enhancement of communication skills with patients with the aid...... is associated with an increased risk of adverse effects, more frequent re-attendance and increased medicalization of self-limiting conditions. Antibiotic overprescribing is a particular problem in primary care, where viruses cause most infections. About 90% of all antibiotic prescriptions are issued by general...

  11. Mental Health and Asian Americans

    Science.gov (United States)

    ... Data > Minority Population Profiles > Asian American > Mental Health Mental Health and Asian Americans Suicide was the 9th leading ... Americans is half that of the White population. MENTAL HEALTH STATUS Serious psychological distress among adults 18 years ...

  12. Infant Mortality and African Americans

    Science.gov (United States)

    ... Profiles > Black/African American > Infant Health & Mortality Infant Mortality and African Americans African Americans have 2.2 ... to receive late or no prenatal care. Infant Mortality Rate Infant mortality rate per 1,000 live ...

  13. African-Americans and Alzheimer's

    Science.gov (United States)

    ... Share Plus on Google Plus African-Americans and Alzheimer's alz.org | IHaveAlz Introduction 10 Warning Signs Brain ... African-Americans are at a higher risk for Alzheimer's disease. Many Americans dismiss the warning signs of ...

  14. Resisting dehumanization

    DEFF Research Database (Denmark)

    Lassen, Inger Marie

    2018-01-01

    Recent years have seen an increase in the influx of asylum-seekers in Scandinavia, and in Denmark this has led to ever-tighter immigration control. This article discusses emerging practices of refugee solidarity and resistance to hegemonic migration policy in Danish civil society in the wake of w...... 2015) and appraisal analysis of the incident in focus. Keywords: immigration, discursive discrimination, populism, solidarity, governmentality, topoi, appraisal...

  15. Contemporary American Physics Fiction.

    Science.gov (United States)

    Friedman, Alan J.

    1979-01-01

    Discusses the works by six contemporary American novelists that illustrate the current state of "physics fiction." The discussed examples of physics fiction ranged from the fluent and frequent inclusion of the casual, to the elaborate systems of physics metaphors. (GA)

  16. American Society of Hematology

    Science.gov (United States)

    ... Navigation Account Navigation Main Content American Society of Hematology ASH Store ASH Job Center ASH Apps Share ... youtube linkedin Research In This Section Agenda for Hematology Research Sickle Cell Priorities Lymphoma Roadmap Moonshot Initiative ...

  17. American Society of Anesthesiologists

    Science.gov (United States)

    ... Trauma ASA and CAE Healthcare’s virtual O.R. Popular Courses Member Exclusive Difficult Airway Algorithm Member login ... You Industry Supporters Whose contributions allow the American Society of Anesthesiologists ® to create world-class education and ...

  18. American Medical Association

    Science.gov (United States)

    ... AMA Wire For healthy individual market, keep tax rules that spur coverage Senate tax plan would scrap ... Foundation AMA Insurance Copyright 1995 - 2017 American Medical Association. All rights reserved. Terms of Use Privacy Policy ...

  19. The American dream

    OpenAIRE

    Camanho, Gilberto Luis

    2015-01-01

    The American dream : literar. Spiegelungen. - In: Weltmacht USA / hrsg. von Josef Becker ... - München : Vögel, 1976. - S. 31-48. - (Schriften der Philosophischen Fachbereiche der Universität Augsburg ; 10)

  20. Singing American History.

    Science.gov (United States)

    Nielsen, Fred

    2001-01-01

    Discusses how to use music when teaching U.S. History. Provides examples such as teaching about the Civil War, the Great Depression, and the Vietnam War and showing the contributions of African Americans. Includes a discography. (CMK)

  1. American Pediatric Surgical Association

    Science.gov (United States)

    American Pediatric Surgical Association Search for: Login Resources + For Members For Professionals For Training Program Directors For Media For ... Surgical Outcomes Surveys & Results Publications Continuing Education + ExPERT Pediatric Surgery NaT Annual Meeting CME MOC Requirements Residents / ...

  2. American Heart Association

    Science.gov (United States)

    ... Americans live with heart disease, stroke or a cardiovascular condition. Your donation will help us save and improve their lives with research, education and emergency care. Warning Signs If you or someone else is ...

  3. American Epilepsy Society

    Science.gov (United States)

    ... for the AES Annual Meeting. More info here . Epilepsy Currents American Epilepsy Society Journal Impact Factor More ... P450 enzyme overexpression during spontaneous recurrent seizures More Epilepsy Professional News AES Status Epilepticus guideline for treatment ...

  4. Profile: Asian Americans

    Science.gov (United States)

    ... Vietnamese, 46 percent of Chinese, 23 percent of Filipinos and 21 percent of Asian Indians are not fluent in English. In 2015, 75.5 percent of Asian American spoke a language other than English at home. Educational Attainment: According ...

  5. NATO: Revisiting American Commitment

    Science.gov (United States)

    2013-03-01

    NATO: Revisiting American Commitment by Captain Thomas F Hurley II United States Navy United...STRATEGY RESEARCH PROJECT .33 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE NATO: Revisiting American Commitment 5a. CONTRACT NUMBER...the 21st century. The strategic benefit to the United States may no longer be worth the commitment to the alliance. The U.S. should reevaluate its

  6. American Studies in Hungary

    Directory of Open Access Journals (Sweden)

    Éva Federmayer

    2006-01-01

    Full Text Available The beginning of American Studies as an academic discipline at Hungarian colleges and universities is basically coterminous with the watershed years of 1989-1990 when the country made a radical shift from state socialism toward parliamentary democracy and a free economy. This political and economic about-face, which came hand in hand with the undermining of foundationalist certainties and the generation of new anxieties coincided, more or less, with the radical transformation that American St...

  7. African Anglo American

    Energy Technology Data Exchange (ETDEWEB)

    Chadwick, J.

    1993-11-01

    The South-African based Anglo-American Corp. dominates the mining industries of South Africa and Botswana and is very important in Namibia, Zimbabwe and Zambia. Most recently it has started prospecting in Tanzania once again. This article discusses the corporation's interests in Africa, gold, copper, diamonds, platinum, nickel and coal, and its interest in South American copper and various African metal industries. 6 refs., 5 figs., 1 tab.

  8. Latin American geo-political struggles in Canadian documentaries production

    Directory of Open Access Journals (Sweden)

    Anelise Reich Corseuil

    2009-01-01

    Full Text Available http://dx.doi.org/10.5007/2175-8026.2009n56p137 This paper analyzes two contemporary Canadian documentaries about Latin American history, specifically the ways in which the films provide an aesthetics of resistance to stereotypical and homogeneous representations of Latin American countries. Canadian documentaries on the history and the people of third world countries not only document Latin American countries but also criticize the conflicting relationships and forms of representation involved in the making of the documentary, revealing the documentary as a narrative form in its making of Latin American subjects and histories. Within this theoretical context, the study here proposed analyses two documentaries about Latin-American geopolitical conflicts. The World is Watching: Inside the News (1988, a British-Canadian production directed by Jim Munro and Peter Raymond, and a Place Called Chiapas, a Canadian production, directed by Nettie Wild (1998.

  9. Survey for the presence of Phytophthora cinnamomi on reclaimed mined lands in Ohio chosen for restoration of the American chestnut

    Science.gov (United States)

    Shiv Hiremath; Kirsten Lehtoma; Jenise M. Bauman

    2013-01-01

    We have been planting blight resistant American chestnut seedlings on reclaimed coal mined areas in Southeastern Ohio, which was once within the natural range of the American chestnut. Towards the goal of restoring the American chestnut, we are testing suitable sites that can aid survival, growth and establishment of planted seedlings pre-inoculated with...

  10. [Resistant hypertension: An update].

    Science.gov (United States)

    Renna, N F

    2018-01-31

    An estimated 10% to 20% of hypertensive patients could be considered resistant to treatment (RH). These are patients who are not controlled using three drugs, at the maximum tolerated doses, including a diuretic, as well as those with high blood pressure controlled using four or more drugs. The term is used to identify patients that might benefit from special diagnostic and/or therapeutic consideration. The term 'refractory hypertension' has recently been proposed as a novel phenotype of antihypertensive failure. It refers to patients whose blood pressure cannot be controlled with maximum treatment. The first studies of this phenotype indicate that it is rare and affects less than 5% of patients with RH. Adherence to or compliance with medical treatment is key to defining resistant hypertension. Closer attention has been paid to clinical and experimental research since the first scientific statement for the diagnosis, assessment and treatment of RH from the American Heart Association, and in the European guidelines, was published in 2008. This review will set out the concepts relating to prevalence, prognosis and compliance and cover the latest developments on this subject. Copyright © 2018 SEH-LELHA. Publicado por Elsevier España, S.L.U. All rights reserved.

  11. Antibiotics and Resistance: Glossary

    Science.gov (United States)

    ... Work Contact Us ABOUT THE ISSUE What is Antibiotic Resistance? General Background Science of Resistance Glossary References ... for Adaptation Genetics and Drug Resistance Reservoirs of Antibiotic Resistance Project (ROAR) INTERNATIONAL CHAPTERS APUA Chapter Network ...

  12. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... Animal & Veterinary Safety & Health Antimicrobial Resistance Animation of Antimicrobial Resistance Share Tweet Linkedin Pin it More sharing options ... of Animation of Antimicrobial Resistance More in Antimicrobial ... Antimicrobial Resistance Monitoring System About NARMS 2015 NARMS Integrated ...

  13. Animation of Antimicrobial Resistance

    Science.gov (United States)

    ... Animal & Veterinary Safety & Health Antimicrobial Resistance Animation of Antimicrobial Resistance Share Tweet Linkedin Pin it More sharing options ... of Animation of Antimicrobial Resistance More in Antimicrobial ... Antimicrobial Resistance Monitoring System About NARMS 2015 NARMS Integrated ...

  14. Insulin Resistance and Prediabetes

    Science.gov (United States)

    ... in the normal range. What happens with insulin resistance? In insulin resistance, muscle, fat, and liver cells do not ... they do not usually test specifically for insulin resistance. Insulin resistance can be assessed by measuring the level ...

  15. Anthelmintic resistance in a herd of alpacas (Vicugna pacos)

    Science.gov (United States)

    Galvan, Noe; Middleton, John R.; Nagy, Dusty W.; Schultz, Loren G.; Schaeffer, Josh W.

    2012-01-01

    A herd of alpacas was examined because of a history of severe endoparasitism, anemia, hypoproteinemia, and weight loss. Resistance of gastrointestinal nematodes to albendazole, fenbendazole, and doramectin was documented. This report suggests that anthelmintic resistance may be an emerging problem in South American camelids in North America. PMID:23729829

  16. Insulin Resistance

    DEFF Research Database (Denmark)

    Jensen, Benjamin Anderschou Holbech

    Insulin resistance (IR) is escalating with alarming pace and is no longer restricted to westernized countries. As a forerunner for some of the most serious threats to human health including metabolic syndrome, cardiovascular diseases, and type 2-diabetes, the need for new treatment modalities...... interventions. We further show that improving the inflammatory toning, using fish oil as fat source, protects mice against diet induced obesity and -inflammation while preserving insulin sensitivity, even in the absence of free fatty acid receptor 4. Conversely, HFD-induced intestinal dysbiosis is associated...

  17. Ceftaroline-Resistant, Daptomycin-Tolerant, and Heterogeneous Vancomycin-Intermediate Methicillin-Resistant Staphylococcus aureus Causing Infective Endocarditis.

    Science.gov (United States)

    Nigo, Masayuki; Diaz, Lorena; Carvajal, Lina P; Tran, Truc T; Rios, Rafael; Panesso, Diana; Garavito, Juan D; Miller, William R; Wanger, Audrey; Weinstock, George; Munita, Jose M; Arias, Cesar A; Chambers, Henry F

    2017-03-01

    We report a case of infective endocarditis (IE) caused by ceftaroline-resistant, daptomycin-tolerant, and heterogeneous vancomycin-intermediate methicillin-resistant S. aureus (MRSA). Resistance to ceftaroline emerged in the absence of drug exposure, and the E447K substitution in the active site of PBP2a previously associated with ceftaroline resistance was identified. Additionally, we present evidence of patient-to-patient transmission of the strain within the same unit. This case illustrates the difficulties in treating MRSA IE in the setting of a multidrug-resistant phenotype. Copyright © 2017 American Society for Microbiology.

  18. Americanization of Non-American Storiesin Disney Films

    OpenAIRE

    Setiawati, Beta

    2008-01-01

    The study is intended to know the Disney’s animation films characteristics which are adapted from non American stories that contain Americanization in order to be American popular culture products. This qualitative and library research is carried out within the field of American Studies. Disney’s animated films which are regarded as artifacts in order to identify American society and culture is used as her primary data. She then compares those Disney films with the original stories to discove...

  19. Reintroduction of American Chestnut in the National Forest System

    Science.gov (United States)

    Stacy L. Clark; Scott E. Schlarbaum; Cornelia C. Pinchot; Sandra L. Anagnostakis; Michael R. Saunders; Melissa Thomas-Van Gundy; Paul Schaberg; James McKenna; Jane F. Bard; Paul C. Berrang; David M. Casey; Chris E. Casey; Barbara Crane; Brian D. Jackson; Jeff D. Kochenderfer; Russ MacFarlane; Robert Makowske; Mark D. Miller; Jason A. Rodrigue; Jim Stelick; Christopher D. Thornton; Tyler S. Williamson

    2014-01-01

    American chestnut restoration depends on a multitude of biological, administrative, and technological factors. Germplasm traditionally bred for resistance to the chestnut blight disease caused by the exotic pathogen Cryphonectria parasitica has been deployed on national forests in the Eastern and Southern Regions of the National Forest System (NFS) since 2009. Trees...

  20. Resistant hypertension.

    Science.gov (United States)

    Armario, P; Oliveras, A; de la Sierra, A

    2013-11-01

    A 53 year old woman with hypercholesterolemia treated with statins, with no history of cardiovascular disease, was referred to the Hypertension and Vascular Risk Unit for management of hypertension resistant to 4 antihypertensive agents at full doses. The patient had obesity, with a body mass index of 36.3kg/m(2) and office blood pressure 162/102mm Hg. Physical examination showed no data of interest. glucose 120mg/dl, glycated Hb: 6.4%, albuminuria 68mg/g, kidney function and study of the renin angiotensin system and other biochemical parameters were normal. Echocardiography: left ventricular mass, 131g/m(2) (normal, <110g/m(2)). True resistant hypertension was confirmed by ambulatory monitoring of blood pressure during 24h (153/89mm Hg). Spironolactone treatment (25mg/day) was added and was well tolerated, with no change in renal function and kaliemia within normal (4.1mmol/l) following the treatment. After 8 weeks, blood pressure was well controlled: office blood pressure 132/86mm Hg and 24h-ambulatory blood pressure: 128/79mm Hg. Copyright © 2013 Elsevier España, S.L. All rights reserved.

  1. Specific Detection and Identification of American Mulberry-Infecting and Italian Olive-Associated Strains of Xylella fastidiosa by Polymerase Chain Reaction.

    Directory of Open Access Journals (Sweden)

    Wei Guan

    Full Text Available Xylella fastidiosa causes bacterial leaf scorch in many landscape trees including elm, oak, sycamore and mulberry, but methods for specific identification of a particular tree host species-limited strain or differentiation of tree-specific strains are lacking. It is also unknown whether a particular landscape tree-infecting X. fastidiosa strain is capable of infecting multiple landscape tree species in an urban environment. We developed two PCR primers specific for mulberry-infecting strains of X. fastidiosa based on the nucleotide sequence of a unique open reading frame identified only in mulberry-infecting strains among all the North and South American strains of X. fastidiosa sequenced to date. PCR using the primers allowed for detection and identification of mulberry-infecting X. fastidiosa strains in cultures and in samples collected from naturally infected mulberry trees. In addition, no mixed infections with or non-specific detections of the mulberry-infecting strains of X. fastidiosa were found in naturally X. fastidiosa-infected oak, elm and sycamore trees growing in the same region where naturally infected mulberry trees were grown. This genotype-specific PCR assay will be valuable for disease diagnosis, studies of strain-specific infections in insects and plant hosts, and management of diseases caused by X. fastidiosa. Unexpectedly but interestingly, the unique open reading frame conserved in the mulberry-infecting strains in the U. S. was also identified in the recently sequenced olive-associated strain CoDiRO isolated in Italy. When the primer set was tested against naturally infected olive plant samples collected in Italy, it allowed for detection of olive-associated strains of X. fastidiosa in Italy. This PCR assay, therefore, will also be useful for detection and identification of the Italian group of X. fastidiosa strains to aid understanding of the occurrence, evolution and biology of this new group of X. fastidiosa strains.

  2. Specific Detection and Identification of American Mulberry-Infecting and Italian Olive-Associated Strains of Xylella fastidiosa by Polymerase Chain Reaction.

    Science.gov (United States)

    Guan, Wei; Shao, Jonathan; Elbeaino, Toufic; Davis, Robert E; Zhao, Tingchang; Huang, Qi

    2015-01-01

    Xylella fastidiosa causes bacterial leaf scorch in many landscape trees including elm, oak, sycamore and mulberry, but methods for specific identification of a particular tree host species-limited strain or differentiation of tree-specific strains are lacking. It is also unknown whether a particular landscape tree-infecting X. fastidiosa strain is capable of infecting multiple landscape tree species in an urban environment. We developed two PCR primers specific for mulberry-infecting strains of X. fastidiosa based on the nucleotide sequence of a unique open reading frame identified only in mulberry-infecting strains among all the North and South American strains of X. fastidiosa sequenced to date. PCR using the primers allowed for detection and identification of mulberry-infecting X. fastidiosa strains in cultures and in samples collected from naturally infected mulberry trees. In addition, no mixed infections with or non-specific detections of the mulberry-infecting strains of X. fastidiosa were found in naturally X. fastidiosa-infected oak, elm and sycamore trees growing in the same region where naturally infected mulberry trees were grown. This genotype-specific PCR assay will be valuable for disease diagnosis, studies of strain-specific infections in insects and plant hosts, and management of diseases caused by X. fastidiosa. Unexpectedly but interestingly, the unique open reading frame conserved in the mulberry-infecting strains in the U. S. was also identified in the recently sequenced olive-associated strain CoDiRO isolated in Italy. When the primer set was tested against naturally infected olive plant samples collected in Italy, it allowed for detection of olive-associated strains of X. fastidiosa in Italy. This PCR assay, therefore, will also be useful for detection and identification of the Italian group of X. fastidiosa strains to aid understanding of the occurrence, evolution and biology of this new group of X. fastidiosa strains.

  3. Resisting dehumanization

    DEFF Research Database (Denmark)

    Lassen, Inger Marie

    2018-01-01

    Recent years have seen an increase in the influx of asylum-seekers in Scandinavia, and in Denmark this has led to ever-tighter immigration control. This article discusses emerging practices of refugee solidarity and resistance to hegemonic migration policy in Danish civil society in the wake...... of an incident from September 2015, when a member of a Danish City Council offered private shelter to immigrants who were on their way to Norway. The incident led to legal proceedings in August 2016 for what the defendant referred to as ‘the offense of helping fellow human beings in need’. The study is informed...... 2015) and appraisal analysis of the incident in focus. Keywords: immigration, discursive discrimination, populism, solidarity, governmentality, topoi, appraisal...

  4. Expanding the Secondary Literature Curriculum: Annotated Bibliographies of American Indian, Asian American, and Hispanic American Literature.

    Science.gov (United States)

    Duff, Ogle B.; Tongchinsub, Helen J.

    1990-01-01

    Aids teachers looking for literature selections of established literary worth which reflect the diversity of American culture. Discusses briefly the history and development of American Indian, Asian American, and Hispanic American literature. Offers annotated bibliographies of selections appropriate for use in secondary schools. (SR)

  5. American Dream / Anu Raat

    Index Scriptorium Estoniae

    Raat, Anu

    2010-01-01

    Uuritakse sõnapaari "American dream" tähendust, kuidas ja millal see unelmalugu tekkis, miks see on ameerikalik nähtus, samuti 1950-ndate moeloomingut, eriti Christian Diori oma Euroopas ja Ameerikas, selle põhjusi ja mõjusid seoses massilise tarbimisega

  6. Americans with Disabilities Act.

    Science.gov (United States)

    Kaesberg, Mary Ann; Murray, Kenneth T.

    1994-01-01

    Presents a 35-item checklist of practical activities for school district compliance with the Americans with Disabilities Act (ADA). The checklist is based on ADA statutes, other civil rights legislation and litigation, as well as pertinent regulations and the legislative history of the act contained in the Congressional Record. (MLF)

  7. American Academy of Audiology

    Science.gov (United States)

    ... Public Relations Toolkit and Hotline to Get Your Practice and Profession into the Media Audiology News 16 Nov A Movement Was Born: ... Academy of Audiology Publications and Resources Audiology Today Journal of the American Academy of Audiology ... About Us Academy Information ...

  8. Teaching Asian American Students.

    Science.gov (United States)

    Chiang, Linda H.

    2000-01-01

    Uses data from interviews with parents of Asian American students, observations, and literature reviews to identify cultural and language issues that must be considered in teaching this population. The paper discusses the history of Asian immigrants, attitudes toward education among Asians, the relationship between teaching styles and Asian…

  9. Grant Wood: "American Gothic."

    Science.gov (United States)

    Fitzgerald, Diane M.

    1988-01-01

    Presents a lesson plan which exposes students in grades 10-12 to the visual symbols and historical references contained in Grant Wood's "American Gothic." Includes background information on the artist and the painting, instructional strategies, a studio activity, and evaluation criteria. (GEA)

  10. American Indian Community Colleges.

    Science.gov (United States)

    One Feather, Gerald

    With the emergence of reservation based community colleges (th Navajo Community College and the Dakota Community Colleges), the American Indian people, as decision makers in these institutions, are providing Indians with the technical skills and cultural knowledge necessary for self-determination. Confronted with limited numbers of accredited…

  11. Civic Innovation & American Democracy.

    Science.gov (United States)

    Sirianni, Carmen; Friedland, Lewis

    1997-01-01

    Argues that American democracy is at a critical stage of development, with declining trust in government, citizens feeling displaced by a professional political class, derailed public interest, and policy that limits citizen deliberation and responsibility. Some instances of civic innovation, community organization, civic journalism, and efforts…

  12. Arab American Voices.

    Science.gov (United States)

    Hall, Loretta

    Through speeches, newspaper accounts, poems, memoirs, interviews, and other materials by and about Arab Americans, this collection explores issues central to what it means to be of Arab descent in the United States today. Each of the entries is accompanied by an introduction, biographical and historical information, a glossary for the selection,…

  13. The Native American Speaks.

    Science.gov (United States)

    Bromberg, Walter; And Others

    This publication is the product of several workshops and is aimed at multi-ethnic integration of teacher attitudes, curriculum content, and teaching techniques. The 7 articles and 3 bibliographies, contributed by Native American consultants, emphasize recognition and alteration of bias in teacher attitudes, curriculum content, and teaching…

  14. Native American Architecture.

    Science.gov (United States)

    Nabokov, Peter; Easton, Robert

    This book presents building traditions of the major Indian tribes in nine regions of the North American continent, from the huge, plankhouse villages of the Northwest Coast, to the moundbuilder towns and temples of the Southeast, to the Navajo hogans and adobe pueblos of the Southwest. Indian buildings are a central element of Indian culture, the…

  15. Characterisation of penA and tetM resistance genes of Neisseria ...

    African Journals Online (AJOL)

    appears to predispose isolates to increased penicillin resistance. The 25,2 MDa conjugative plasmid carrying the. tetM resistance determinant was readily demonstrated in. 11 Botswana! Namibia isolates exhibiting high-level resistance to tetracycline (MICs ? 16 IJg/ml). The tetM gene was shown to be of the American type.

  16. Acquisition of Broad-Spectrum Cephalosporin Resistance Leading to Colistin Resistance in Klebsiella pneumoniae.

    Science.gov (United States)

    Jayol, Aurélie; Nordmann, Patrice; Desroches, Marine; Decousser, Jean-Winoc; Poirel, Laurent

    2016-05-01

    An extended-spectrum β-lactamase (ESBL)-producing and colistin-resistant Klebsiella pneumoniae clinical isolate was recovered from a patient who was treated with cefotaxime. This isolate harbored a blaCTX-M-15 ESBL gene that was associated with an ISEcp1 insertion sequence. Transposition of that tandem occurred within the chromosomal mgrB gene, leading to inactivation of the mgrB gene and consequently to acquired resistance to colistin. We showed here a coselection of colistin resistance as a result of a broad-spectrum cephalosporin selective pressure. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  17. [Change in drug resistance of Staphylococcus aureus].

    Science.gov (United States)

    Lin, Yan; Liu, Yan; Luo, Yan-Ping; Liu, Chang-Ting

    2013-11-01

    To analyze the change in drug resistance of Staphylococcus aureus (SAU) in the PLA general hospital from January 2008 to December 2012, and to provide solid evidence to support the rational use of antibiotics for clinical applications. The SAU strains isolated from clinical samples in the hospital were collected and subjected to the Kirby-Bauer disk diffusion test. The results were assessed based on the 2002 American National Committee for Clinical Laboratory Standards (NCCLS) guidelines. SAU strains were mainly isolated from sputum, urine, blood and wound excreta and distributed in penology, neurology wards, orthopedics and surgery ICU wards. Except for glycopeptide drugs, methicillin-resistant Staphylococcus aureus (MRSA) had a higher drug resistance rate than those of the other drugs and had significantly more resistance than methicillin-sensitive Staphylococcus aureus (MSSA) (P resistance, we discovered a gradual increase in drug resistance to fourteen test drugs during the last five years. Drug resistance rate of SAU stayed at a higher level over the last five years; moreover, the detection ratio of MRSA keeps rising year by year. It is crucial for physicians to use antibiotics rationally and monitor the change in drug resistance in a dynamic way.

  18. Silvicultural and logistical considerations associated with the pending reintroduction of American chestnut

    Science.gov (United States)

    Douglass F. Jacobs

    2010-01-01

    Traditional breeding for blight resistance has led to the potential to restore American chestnut (Castanea dentata (Marsh.) Borkh.) to Eastern United States forests using a blight resistant hybrid chestnut tree. With prospects of pending wide-scale reintroduction, restoration strategies based on ecological and biological characteristics of the...

  19. Quantitative Resistance: More Than Just Perception of a Pathogen.

    Science.gov (United States)

    Corwin, Jason A; Kliebenstein, Daniel J

    2017-04-01

    Molecular plant pathology has focused on studying large-effect qualitative resistance loci that predominantly function in detecting pathogens and/or transmitting signals resulting from pathogen detection. By contrast, less is known about quantitative resistance loci, particularly the molecular mechanisms controlling variation in quantitative resistance. Recent studies have provided insight into these mechanisms, showing that genetic variation at hundreds of causal genes may underpin quantitative resistance. Loci controlling quantitative resistance contain some of the same causal genes that mediate qualitative resistance, but the predominant mechanisms of quantitative resistance extend beyond pathogen recognition. Indeed, most causal genes for quantitative resistance encode specific defense-related outputs such as strengthening of the cell wall or defense compound biosynthesis. Extending previous work on qualitative resistance to focus on the mechanisms of quantitative resistance, such as the link between perception of microbe-associated molecular patterns and growth, has shown that the mechanisms underlying these defense outputs are also highly polygenic. Studies that include genetic variation in the pathogen have begun to highlight a potential need to rethink how the field considers broad-spectrum resistance and how it is affected by genetic variation within pathogen species and between pathogen species. These studies are broadening our understanding of quantitative resistance and highlighting the potentially vast scale of the genetic basis of quantitative resistance. © 2017 American Society of Plant Biologists. All rights reserved.

  20. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... Veterinary Safety & Health Antimicrobial Resistance Animation of Antimicrobial Resistance Share Tweet Linkedin Pin it More sharing options ... produced a nine-minute animation explaining how antimicrobial resistance both emerges and proliferates among bacteria. Over time, ...

  1. HIV Resistance Testing

    Science.gov (United States)

    ... 14, 2016 Select a Language: Fact Sheet 126 HIV Resistance Testing WHAT IS RESISTANCE? HOW DOES RESISTANCE ... ARVs. If you miss doses of your medications, HIV will multiply more easily. More mutations will occur. ...

  2. Combating Antibiotic Resistance

    Science.gov (United States)

    ... in Farm Animals FDA: Cutting-Edge Technology Sheds Light on Antibiotic Resistance For More Information Antibiotics and Antibiotic Resistance Antimicrobial Resistance Information for Consumers and Health Professionals CDC: Get Smart: Know When Antibiotics Work More in Consumer Updates ...

  3. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... Veterinary Home Animal & Veterinary Safety & Health Antimicrobial Resistance Animation of Antimicrobial Resistance Share Tweet Linkedin Pin it ... Veterinary Medicine is cited as the corporate author. Animation Animation of Antimicrobial Resistance (video) Animation of Antimicrobial ...

  4. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... Antimicrobial Resistance More in Antimicrobial Resistance National Antimicrobial Resistance Monitoring System About NARMS 2015 NARMS Integrated Report Data Meetings and Publications Resources Judicious Use of Antimicrobials Page Last Updated: ...

  5. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... Animal & Veterinary Safety & Health Antimicrobial Resistance Animation of Antimicrobial Resistance Share Tweet Linkedin Pin it More sharing options ... CVM) produced a nine-minute animation explaining how antimicrobial resistance both emerges and proliferates among bacteria. Over time, ...

  6. The American Armies: 1993

    Science.gov (United States)

    1994-01-01

    Liberation Front) in El Salvador has evaporated, paving the way for resolution of El Salvador’s civil conflict. A minor "reverse domino" effect is...being felt throughout Latin America. As the conflict in El Salvador subsided, Honduran fears about the size of El Salvadoran forces have eased, resulting...30 American nations, especially since US. participation in the overthrow of Allende in 1973.21 Bolivia’s aspirations for direct access to the Pacific

  7. Evaluating methyl jasmonate for induction of resistance to Fusarium oxysporum, F. circinatum and Ophiostoma novo-ulmi

    Energy Technology Data Exchange (ETDEWEB)

    Vivas, M.; Martin, J. a.; Gil, L.; Solla, A.

    2012-11-01

    Damping off is probably the most common disease affecting seedlings in forest nurseries. In south-western Europe, the pitch canker and the Dutch elm disease cause relevant economic looses in forests, mostly in adult trees. The ability of the chemical plant elicitor methyl jasmonate (MeJA) to induce resistance in Pinus pinaster against Fusarium oxysporum and F. circinatum, and in Ulmus minor against Ophiostoma novo-ulmi was examined. In a first experiment, an aqueous solution of MeJA 5 mM was applied to P. pinaster seeds by immersion or spray, and different concentrations of MeJA (0, 0.1, 0.5, 1, 5 and 10 mM) were tested in seedlings before inoculations with F. oxysporum (105 and 107 spores mL{sup -}1). In a second experiment, 6-months-old P. pinaster seedlings were sprayed with 0 and 25 mM of MeJA, and later challenged with mycelium of F. circinatum. Finally, 4-year-old U. minor trees were sprayed with 0, 50 and 100 mM of MeJA and subsequently inoculated with O. novo-ulmi (106 spores mL{sup -}1). MeJA did not protect P. pinaster seeds and seedlings against F. oxysporum, probably because plants were too young for the physiological mechanisms responsible for resistance to be induced. Based on the morphological changes observed in the treated 6-months-old P. pinaster seedlings (reduction of growth and increased resin duct density), there is evidence that MeJA could have activated the mechanisms of resistance. However, 25 mM MeJA did not reduce plant mortality, probably because the spread of the virulent F. circinatum strain within the tree tissues was faster than the formation of effective defense responses. Based on the lack of phenological changes observed in the treated elms, there is no evidence that MeJA would cause induction of resistance. These results suggest that the use of MeJA to prevent F. oxysporum and F. circinatum in P. pinaster seedlings in nurseries and O. novo-ulmi in U. minor trees should be discarded. (Author) 42 refs.

  8. Induced resistance: an enhancement of basal resistance?

    NARCIS (Netherlands)

    Vos, M. de; Robben, C.; Pelt, J.A. van; Loon, L.C. van; Pieterse, C.M.J.

    2002-01-01

    Upon primary pathogen attack, plants activate resistance mechanisms at the site of infection. Besides this so-called basal resistance, plants have also the ability to enhance their defensive capacity against future pathogen attack. There are at least two types of biologically induced resistance.

  9. Mental Health and African Americans

    Science.gov (United States)

    ... Minority Population Profiles > Black/African American > Mental Health Mental Health and African Americans Poverty level affects mental health ... compared to 120% of non-Hispanic whites. 1 MENTAL HEALTH STATUS Serious psychological distress among adults 18 years ...

  10. American Head and Neck Society

    Science.gov (United States)

    American Head & Neck Society Mission Statement: Advance Education, Research, and Quality of Care for the head and neck oncology patient. American Head & Neck Society | AHNS The mission of the AHNS is to ...

  11. Native Americans' Interest in Horticulture.

    Science.gov (United States)

    Meyer, Mary Hockenberry

    1999-01-01

    Focus groups arranged by local Native American Master Gardeners on two Minnesota reservations determined community interest in extension-horticulture programs. Topics of interest included food preservation and historical Native-American uses of plants. (SK)

  12. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... More in Antimicrobial Resistance National Antimicrobial Resistance Monitoring System About NARMS 2015 NARMS Integrated Report Data Meetings and Publications Resources Judicious Use of ...

  13. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... More in Antimicrobial Resistance National Antimicrobial Resistance Monitoring System ... If you need help accessing information in different file formats, see Instructions for Downloading ...

  14. Discrimination against Muslim American Adolescents

    Science.gov (United States)

    Aroian, Karen J.

    2012-01-01

    Although there is ample evidence of discrimination toward Muslim Americans in general, there is limited information specific to Muslim American adolescents. The few existing studies specific to this age group suggest that Muslim American adolescents encounter much discrimination from teachers, school administrators, and classmates. This…

  15. Native American Ceremonial Athletic Games.

    Science.gov (United States)

    Pesavento, Wilma J.

    This is a report on the relationship of North American Indian athletic games to ceremonies. Data for this investigation were researched from 48 "Annual Reports of the Bureau of American Ethnology, Smithsonian Institution" published from 1881 to 1933, and the 84 volumes of the "American Anthropologist" published from 1888 to 1974. Observational…

  16. American Food and World Hunger.

    Science.gov (United States)

    Czarra, Fred R.; Long, Cathryn J., Eds.

    1983-01-01

    Describes activities to help students in grades 7-9 learn about American food production and distribution. Students learn about the American diet over the centuries; the production of American Corn; the meaning of the term hunger; and the need for protein. (CS)

  17. African-American wildland memories

    Science.gov (United States)

    Cassandra Y. Johnson; J. Michael Bowker

    2004-01-01

    Collective memory can be used conceptually to examine African-American perceptions of wildlands and black interaction with such places. The middle--American view of wildlands frames these terrains as refuges--pure and simple, sanctified places distinct from the profanity of human modification. However, wild, primitive areas do not exist in the minds of all Americans as...

  18. The growing problem of antimicrobial resistance

    DEFF Research Database (Denmark)

    Holmstrup, Palle; Klausen, Bjarne

    2018-01-01

    Antibiotic therapy over the years has saved millions of lives, but antimicrobial resistance (AMR) is a current threat to human health. An interesting review on AMR has recently been presented in the Journal of American Medical Association (Marston et al., 2016). The review is authored by five staff...... members at National Institutes of Health in Bethesda, Maryland, and the purpose of the review was to identify factors associated with AMR, the current epidemiology of important resistant organisms, and possible solutions to the AMR problem. This article is protected by copyright. All rights reserved....

  19. Celebrating National American Indian Heritage Month

    National Research Council Canada - National Science Library

    Mann, Diane

    2004-01-01

    .... Installation planning for American Indian Heritage Month should incorporate cultural traditions and history specific to Native Americans of the area, patriotism of Native Americans who have served...

  20. History of Asian American psychology.

    Science.gov (United States)

    Leong, Frederick T L; Okazaki, Sumie

    2009-10-01

    An overview of the history of Asian American psychology is provided by reviewing the context for the development of the field as well as the early founding of the Asian American Psychological Association (AAPA). The presidents of AAPA as well as key events and conferences are noted. The involvement of AAPA leaders in national mental health policies and activities are reviewed. The substantive areas of Asian American psychology and the education and training of Asian American psychologists are also discussed. The article ends with some comments about the future of Asian American psychology. Copyright 2009 APA, all rights reserved.