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Sample records for resistance forced vital

  1. The relationship between obesity and forced vital capacity among university students.

    Science.gov (United States)

    Sun, Xugui; Chen, Xiaohong

    2015-05-01

    We sought to explore the relationship between vital capacity and obesity among university students in China. A cross-sectional study was designed to collect the routine health screening data for university students in 2013. The height, weight and force vital capacity of students were measured, and BMI was calculated with height and weight, so as to estimate the relationship between force vital capacity and obesity. Based on Working Group on Obesity references in China, obesity has a higher force vital capacity in both male and female university students. No correlation was found between vital capacity and BMI. obesity may have effect on pulmonary function among university students, which is a reference for further epidemic study. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  2. Explanatory models for homeopathy: from the vital force to the current paradigm.

    Science.gov (United States)

    Waisse, Silvia; Bonamin, Leoni Villano

    2016-08-01

    Facing claims for and against the scientific status of homeopathy, one is entitled to ask: is there a scientific model for homeopathy? In this study we reconstructed the model put forward by Hahnemann. The results showed that it was essentially based on the assumption of a 'vital force' exclusive to living beings. While the vital force was a basic element of 18th-century science, the existence of such a sui generis force of nature was refuted with the formulation of the law of the conservation of energy by mid-19th century. As a function of that fact for homeopathic theory, we discuss the history of the rise and demise of the theory of the vital force from the last quarter of the 18th century to 1830. Finally, we call the attention to the paradigm shift biology underwent starting at the end of the 19th century as the framework for contemporary views on the functioning of living beings and consequently, of the effects of pharmacological agents on them. Copyright © 2016 The Faculty of Homeopathy. Published by Elsevier Ltd. All rights reserved.

  3. VARIABILITY OF FORCED OSCILLATION (SIEMENS SIREGNOST FD-5) MEASUREMENTS OF TOTAL RESPIRATORY RESISTANCE IN PATIENTS AND HEALTHY-SUBJECTS

    NARCIS (Netherlands)

    GIMENO, F; VANDERWEELE, LT; KOETER, GH; DEMONCHY, JGR; VANALTENA, R

    The reproducibility of total respiratory resistance (R(rs)) measured with a simplified forced oscillatory method (Siemens Siregnost FD 5) was measured and compared with that of slow inspiratory vital capacity (IVC) and forced expiratory volume in one second (FEV1). The former technique has the

  4. Vital forces and organization: philosophy of nature and biology in Karl Friedrich Kielmeyer.

    Science.gov (United States)

    Gambarotto, Andrea

    2014-12-01

    The historical literature on German life science at the end of the 18th century has tried to rehabilitate eighteenth century vitalism by stressing its difference from Naturphilosophie. Focusing on the work of Karl Friedrich Kielmeyer this paper argues that these positions are based on a historiographical bias and that the clear-cut boundary between German vitalism and Naturphilosophie is historically unattested. On the contrary, they both belong to the process of conceptual genealogy that contributed to the project of a general biology. The latter emerged as the science concerned with the laws that regulate the organization of living nature as a whole. The focus on organization was, at least partially, the result of the debate surrounding the notion of "vital force", which originated in the mid-eighteenth century and caused a shift from a regulative to a constitutive understanding of teleology. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Patterns of Force, Sequences of Resistance

    DEFF Research Database (Denmark)

    Lindegaard, Marie Rosenkrantz; Daniël De Vries, Thomas; Bernasco, Wim

    2018-01-01

    Robberies are improvised encounters involving offender threat, sometimes force, and often victim resistance. While the association between threat, force, and resistance in robberies is well-established, sequential patterns are disputed due to biases of retrospective studies. To overcome these bia...... the likelihood of victim resistance despite having no effect on offender vio- lence. By providing more reliable and detailed accounts of real-life behavior during robberies, our analysis illustrates the potential of a newly emergent field of studies of crimes caught on camera....

  6. Forced harmonic oscillations of the Euler-Bernoulli beam with resistance forces

    Directory of Open Access Journals (Sweden)

    Yuriy S. Krutiy

    2015-12-01

    Full Text Available The important issue in the oscillation theory is the study of resistance impact on oscillatory processes. Unlike the calculations of free oscillations, that reside in determination of natural frequencies and waveshapes and unlike the calculations of forced oscillations far away from resonance, that are performing without reference to friction, the oscillations researches in vicinity of resonance need accounting of friction forces. Special attention is paid to forced transverse fluctuations in beams as an important technical problem for engineering and building. Aim: The aim of the work is constructing of analytical solution of the problem of forced transverse vibrations of a straight rod with constant cross-section, which is under the influence of the harmonic load taking into account external and internal resistances. Materials and Methods: The internal resistance is taken into account using the corrected hypothesis of Kelvin-Voigt which reflects the empirically proven fact about the frequency-independent internal friction in the material. The external friction is also considered as frequency-independent. Results: An analytical solution is built for the differential equation of forced transverse oscillations of a straight rod with constant cross-section which is under the influence of the harmonic load taking into account external and internal resistances. As a result, analytically derived formulae are presented which describe the forced dynamic oscillations and the dynamic internal forces due to the harmonic load applied to the rod thus reducing the problem with any possible fixed ends to the search of unknown integration constants represented in a form of initial parameters.

  7. The health sciences librarian in medical education: a vital pathways project task force.

    Science.gov (United States)

    Schwartz, Diane G; Blobaum, Paul M; Shipman, Jean P; Markwell, Linda Garr; Marshall, Joanne Gard

    2009-10-01

    The Medical Education Task Force of the Task Force on Vital Pathways for Hospital Librarians reviewed current and future roles of health sciences librarians in medical education at the graduate and undergraduate levels and worked with national organizations to integrate library services, education, and staff into the requirements for training medical students and residents. Standards for medical education accreditation programs were studied, and a literature search was conducted on the topic of the role of the health sciences librarian in medical education. Expectations for library and information services in current standards were documented, and a draft standard prepared. A comprehensive bibliography on the role of the health sciences librarian in medical education was completed, and an analysis of the services provided by health sciences librarians was created. An essential role and responsibility of the health sciences librarian will be to provide the health care professional with the skills needed to access, manage, and use library and information resources effectively. Validation and recognition of the health sciences librarian's contributions to medical education by accrediting agencies will be critical. The opportunity lies in health sciences librarians embracing the diverse roles that can be served in this vital activity, regardless of accrediting agency mandates.

  8. Influence of Isoinertial-Pneumatic Mixed Resistances on Force-Velocity Relationship.

    Science.gov (United States)

    Avrillon, Simon; Jidovtseff, Boris; Hug, François; Guilhem, Gaël

    2017-03-01

    Muscle strengthening is commonly based on the use of isoinertial loading, whereas variable resistances such as pneumatic loading may be implemented to optimize training stimulus. The purpose of the current study was to determine the effect of the ratio between pneumatic and isoinertial resistance on the force-velocity relationship during ballistic movements. A total of 15 participants performed 2 concentric repetitions of ballistic bench-press movements with intention to throw the bar at 30%, 45%, 60%, 75%, and 90% of the maximal concentric repetition with 5 resistance ratios including 100%, 75%, 50%, 25%, or 0% of pneumatic resistance, the additional load being isoinertial. Force-, velocity-, and power-time patterns were assessed and averaged over the concentric phase to determine the force-velocity and power-velocity relationships for each resistance ratio. Each 25% increase in the pneumatic part in the resistance ratio elicited higher movement velocity (+0.11 ± 0.03 m/s from 0% to 80% of the concentric phase) associated with lower force levels (-43.6 ± 15.2 N). Increased isoinertial part in the resistance ratio resulted in higher velocity toward the end of the movement (+0.23 ± 0.01 m/s from 90% to 100%). The findings show that the resistance ratio could be modulated to develop the acceleration phase and force toward the end of the concentric phase (pneumatic-oriented resistance). Inversely, isoinertial-oriented resistance should be used to develop maximal force and maximal power. Resistance modality could, therefore, be considered an innovative variable to modulate the training stimulus according to athletic purposes.

  9. Galileo's kinematical paradox and the role of resistive forces

    International Nuclear Information System (INIS)

    Aguiar, C E; Soares, V; Tort, A C

    2014-01-01

    We discuss Galileo's kinematical ‘paradox’ taking into account the effects of sliding friction and of resistive forces proportional to velocity. We show that sliding friction eliminates the paradox but still allows for very simple synchronous curves. Perhaps surprisingly, Galileo's paradox is preserved when the resistive force is proportional to velocity. (paper)

  10. Study on a mechanical snubber with an adjustment mechanism for resisting force

    International Nuclear Information System (INIS)

    Ohmata, Kenichiro; Miyanaga, Hiroyuki.

    1991-01-01

    The mechanical snubber is an earthquakeproof device for a piping system under particular circumstances such as high temperature and radioactivity. It restrains the piping system by a strong resisting force during an earthquake. This strong force can cause elastic failure of grooves on a brake disk, where steel balls are placed. In this report, an improved mechanical snubber having an adjustment mechanism for resisting force is proposed in order to obtain a mechanical snubber which has almost the same restraint effect and less resisting force in comparison with a conventional mechanical snubber. The resisting force characteristics and the restraint effect of the improved mechanical snubber applied to a simple beam are discussed both numerically and experimentally. The digital simulations are carried out using the Continuous System Simulation Language (CSSL). (author)

  11. CDC Vital Signs: Legionnaires' Disease

    Science.gov (United States)

    ... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

  12. Vital and dispensable roles of Plasmodium multidrug resistance transporters during blood- and mosquito-stage development.

    Science.gov (United States)

    Rijpma, Sanna R; van der Velden, Maarten; Annoura, Takeshi; Matz, Joachim M; Kenthirapalan, Sanketha; Kooij, Taco W A; Matuschewski, Kai; van Gemert, Geert-Jan; van de Vegte-Bolmer, Marga; Siebelink-Stoter, Rianne; Graumans, Wouter; Ramesar, Jai; Klop, Onny; Russel, Frans G M; Sauerwein, Robert W; Janse, Chris J; Franke-Fayard, Blandine M; Koenderink, Jan B

    2016-07-01

    Multidrug resistance (MDR) proteins belong to the B subfamily of the ATP Binding Cassette (ABC) transporters, which export a wide range of compounds including pharmaceuticals. In this study, we used reverse genetics to study the role of all seven Plasmodium MDR proteins during the life cycle of malaria parasites. Four P. berghei genes (encoding MDR1, 4, 6 and 7) were refractory to deletion, indicating a vital role during blood stage multiplication and validating them as potential targets for antimalarial drugs. Mutants lacking expression of MDR2, MDR3 and MDR5 were generated in both P. berghei and P. falciparum, indicating a dispensable role for blood stage development. Whereas P. berghei mutants lacking MDR3 and MDR5 had a reduced blood stage multiplication in vivo, blood stage growth of P. falciparum mutants in vitro was not significantly different. Oocyst maturation and sporozoite formation in Plasmodium mutants lacking MDR2 or MDR5 was reduced. Sporozoites of these P. berghei mutants were capable of infecting mice and life cycle completion, indicating the absence of vital roles during liver stage development. Our results demonstrate vital and dispensable roles of MDR proteins during blood stages and an important function in sporogony for MDR2 and MDR5 in both Plasmodium species. © 2016 John Wiley & Sons Ltd.

  13. Comparison of resistive heating and forced-air warming to prevent inadvertent perioperative hypothermia.

    Science.gov (United States)

    John, M; Crook, D; Dasari, K; Eljelani, F; El-Haboby, A; Harper, C M

    2016-02-01

    Forced-air warming is a commonly used warming modality, which has been shown to reduce the incidence of inadvertent perioperative hypothermia (heating mattresses offer a potentially cheaper alternative, however, and one of the research recommendations from the National Institute for Health and Care Excellence was to evaluate such devices formally. We conducted a randomized single-blinded study comparing perioperative hypothermia in patients receiving resistive heating or forced-air warming. A total of 160 patients undergoing non-emergency surgery were recruited and randomly allocated to receive either forced-air warming (n=78) or resistive heating (n=82) in the perioperative period. Patient core temperatures were monitored after induction of anaesthesia until the end of surgery and in the recovery room. Our primary outcome measures included the final intraoperative temperature and incidence of hypothermia at the end of surgery. There was a significantly higher rate of hypothermia at the end of surgery in the resistive heating group compared with the forced-air warming group (P=0.017). Final intraoperative temperatures were also significantly lower in the resistive heating group (35.9 compared with 36.1°C, P=0.029). Hypothermia at the end of surgery in both warming groups was common (36% forced air warming, 54% resistive heating). Our results suggest that forced-air warming is more effective than resistive heating in preventing postoperative hypothermia. NCT01056991. © The Author 2016. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  14. CDC Vital Signs-Protect Patients from Antibiotic Resistance

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the March 2016 CDC Vital Signs report. Patients can get serious healthcare-associated infections, or HAIs, while receiving medical treatment in a healthcare facility. Learn how to prevent healthcare-associated infections.

  15. Early and late rate of force development: differential adaptive responses to resistance training?

    DEFF Research Database (Denmark)

    Andersen, L L; Andersen, Jesper Løvind; Zebis, M K

    2010-01-01

    The objective of this study is to investigate the potentially opposing influence of qualitative and quantitative muscular adaptations in response to high-intensity resistance training on contractile rate of force development (RFD) in the early (200 ms) of rising muscle force. Fifteen healthy young......-intensity resistance training due to differential influences of qualitative and quantitative muscular adaptations on early and later phases of rising muscle force....... males participated in a 14-week resistance training intervention for the lower body and 10 matched subjects participated as controls. Maximal muscle strength (MVC) and RFD were measured during maximal voluntary isometric contraction of the quadriceps femoris muscle. Muscle biopsies were obtained from...

  16. CDC Vital Signs: Asthma in the US

    Science.gov (United States)

    ... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

  17. CDC Vital Signs: HIV Care Saves Lives

    Science.gov (United States)

    ... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

  18. Perceived causality, force, and resistance in the absence of launching.

    Science.gov (United States)

    Hubbard, Timothy L; Ruppel, Susan E

    2017-04-01

    In the launching effect, a moving object (the launcher) contacts a stationary object (the target), and upon contact, the launcher stops and the target begins moving in the same direction and at the same or slower velocity as previous launcher motion (Michotte, 1946/1963). In the study reported here, participants viewed a modified launching effect display in which the launcher stopped before or at the moment of contact and the target remained stationary. Participants rated perceived causality, perceived force, and perceived resistance of the launcher on the target or the target on the launcher. For launchers and for targets, increases in the size of the spatial gap between the final location of the launcher and the location of the target decreased ratings of perceived causality and ratings of perceived force and increased ratings of perceived resistance. Perceived causality, perceived force, and perceived resistance exhibited gradients or fields extending from the launcher and from the target and were not dependent upon contact of the launcher and target. Causal asymmetries and force asymmetries reported in previous studies did not occur, and this suggests that such asymmetries might be limited to typical launching effect stimuli. Deviations from Newton's laws of motion are noted, and the existence of separate radii of action extending from the launcher and from the target is suggested.

  19. Analysis on the resistive force in penetration of a rigid projectile

    Directory of Open Access Journals (Sweden)

    Xiao-wei Chen

    2014-09-01

    Full Text Available According to the dimensionless formulae of DOP (depth of penetration of a rigid projectile into different targets, the resistive force which a target exerts on the projectile during the penetration of rigid projectile is theoretically analyzed. In particular, the threshold Vc of impact velocity applicable for the assumption of constant resistive force is formulated through impulse analysis. The various values of Vc corresponding to different pairs of projectile-target are calculated, and the consistency of the relative test data and numerical results is observed.

  20. Cyclic Vitalism

    DEFF Research Database (Denmark)

    Halse, Sven

    2014-01-01

    of taking such a unilateral view of what constituted a Vitalist concept of life. It could lead to a misunderstanding of Vitalist way of thinking, Rasch said, if the focus were only set upon the enthusiastic surplus, the worshipping of youth and health. To Vitalists, life is more than that. It is a totality...... of the era. The analyses include a further sub-categorisation to capture the different types of Life Force dealt with in the texts. By way of an introduction, Vitalism is discussed within the context of the scientific and social developments of the 19th Century....

  1. Change Agent – A Force Generating Resistance To Change Within An Organization?

    Directory of Open Access Journals (Sweden)

    Mariana Prediscan

    2012-12-01

    Full Text Available The purpose of this research is to identify if the change agent represents or not a force generating resistance to change within an organization. The employees affected by a change process are usually the ones who oppose to new implementations. Their opposition is bigger or smaller, depending on the extent that they are affected and also by the direction, either positive or negative. However, employee’s opposition can be potentiated or reduced, depending on the manifestation of the following forces within an organization: communications, the type of organizational structure, management style and organizational culture, forces which refer to the organizational climate. To answer our question, we have researched the current literature and discovered that the change agent can represent a force generating resistance to change within an organization in those situations when he or she identifies with a middle or top manager from the organizational pyramid. This information is valuable to researchers and practitioners, as for a long time, employees were considered the only ones manifesting resistance, the possibility that the change agent can oppose new changes being ignored.

  2. CDC Vital Signs-Protect Patients from Antibiotic Resistance

    Centers for Disease Control (CDC) Podcasts

    2016-03-03

    This podcast is based on the March 2016 CDC Vital Signs report. Patients can get serious healthcare-associated infections, or HAIs, while receiving medical treatment in a healthcare facility. Learn how to prevent healthcare-associated infections.  Created: 3/3/2016 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 3/3/2016.

  3. An evaluation of So language vitality in Thailand

    Directory of Open Access Journals (Sweden)

    Thomas M. Tehan

    2017-07-01

    Full Text Available This paper explores the vitality and endangerment of So [sss] speech communities in Thailand. Beginning with a review of sociolinguistic survey results for five So communities in Thailand to ascertain the likely need for vernacular language development in So, additional data to cover the rest of the So community are provided. The language vitality of the So communities in Thailand is then assessed using Expanded GIDS and the Sustainable Use Model (SUM, Lewis & Simons 20152, an expansion of the Graded Intergenerational Disruption Scale (GIDS, Fishman 1991. This vitality model indicates that many So villages display vigorous language vitality whereas other villages are threatened by language shift. Some initial efforts at revitalization and language development show promise. Several additional activities are suggested to enhance the vitality of the language and help the So to resist the regional trend towards language shift to Northeastern Thai (Isaan.

  4. CDC Vital Signs-Communication Can Save Lives

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the August 2015 CDC Vital Signs report. Antibiotic-resistant germs cause at least 23,000 deaths each year. Learn how public health authorities and health care facilities can work together to save lives.

  5. Resistance to alveolar shape change limits range of force propagation in lung parenchyma.

    Science.gov (United States)

    Ma, Baoshun; Smith, Bradford J; Bates, Jason H T

    2015-06-01

    We have recently shown that if the lung parenchyma is modeled in 2 dimensions as a network of springs arranged in a pattern of repeating hexagonal cells, the distortional forces around a contracting airway propagate much further from the airway wall than classic continuum theory predicts. In the present study we tested the hypothesis that this occurs because of the negligible shear modulus of a hexagonal spring network. We simulated the narrowing of an airway embedded in a hexagonal network of elastic alveolar walls when the hexagonal cells of the network offered some resistance to a change in shape. We found that as the forces resisting shape change approach about 10% of the forces resisting length change of an individual spring the range of distortional force propagation in the spring network fell of rapidly as in an elastic continuum. We repeated these investigations in a 3-dimensional spring network composed of space-filling polyhedral cells and found similar results. This suggests that force propagation away from a point of local parenchymal distortion also falls off rapidly in real lung tissue. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Energy and environmental norms on Minimum Vital Flux

    International Nuclear Information System (INIS)

    Maran, S.

    2008-01-01

    By the end of the year will come into force the recommendations on Minimum Vital flow and operators of hydroelectric power plants will be required to make available part of water of their derivations in order to protect river ecosystems. In this article the major energy and environmental consequences of these rules, we report some quantitative evaluations and are discusses the proposals for overcoming the weaknesses of the approach in the estimation of Minimum Vital Flux [it

  7. [The influence of occlusal interferences on pulp vitality threshold in permanent dentition].

    Science.gov (United States)

    Hejne, Arletta Julita

    2003-01-01

    Examination of pulp vitality is a valuable aid in diagnosis and treatment and thus has been in use for a long time. Numerous factors influencing the pain threshold have been found including occlusal interferences. The effect of EOI (Experimental Occlusal Interferences) has been described, while the effect of primary occlusal interference awaits further investigation. The aim of this work was to evaluate the influence of malocclusion (primary occlusal interference) on pulp vitality. At first, the pattern of bite forces in normal occlusion was established. For this purpose, 20 individuals were examined. The following results were found: (a) Bite forces on the right and left side are symmetrical; (b) Total bite forces are distributed as follows: (I) upper half arch: medial incisor 6.3%, lateral incisor 2.9%, canine 3.6%, first premolar 10.4%, second premolar 11.7%, first molar 29.4%, second molar 23.8%; (II) lower half arch: medial incisor 4.1%, lateral incisor 4%, canine 4.8%, first premolar 9%, second premolar 15.1%, first molar 27.3%, second molar 29.7% (Fig. 4). Next, 83 patients with unilateral malocclusion were subjected to clinical examination (orthodontic diagnosis) and measurement of bite forces (with T-Scan system). A computer program was used to establish bite forces (in %) for each tooth. 576 teeth were divided into 9 groups in accordance with the orthodontic diagnosis as follows: class II tendency (n = 126), cross-bite (n = 50), rotated (n = 30), scissors bite (n = 23), class III tendency (n = 19), class II (n = 16), open bite (n = 15), class III (n = 9), normal occlusion (n = 288). Each tooth in malocclusion was assigned a contralateral "control" tooth (Fig. 5). Bite forces acting on teeth in malocclusion were compared with control teeth using Student's t-test (Fig. 6). There is no difference between bite forces of teeth in normal occlusion and malocclusion on the opposite side of dental arches in the same patient, the only exceptions being open and

  8. Effect of simulated resistance, fleeing, and use of force on standardized field sobriety testing.

    Science.gov (United States)

    Ho, Jeffrey; Dawes, Donald; Nystrom, Paul; Moore, Johanna; Steinberg, Lila; Tilton, Annemarie; Miner, James

    2015-07-01

    When a law enforcement officer (LEO) stops a suspect believed to be operating (a vehicle) while impaired (OWI), the suspect may resist or flee, and the LEO may respond with force. The suspect may then undergo a Standardized Field Sobriety Test (SFST) to gauge impairment. It is not known whether resistance, fleeing, or actions of force can create an inaccurate SFST result. We examined the effect of resistance, fleeing, and force on the SFST. Human volunteers were prospectively randomized to have a SFST before and after one of five scenarios: (1) five-second conducted electrical weapon exposure; (2) 100-yard (91.4 m) sprint; (3) 45-second physical fight; (4) police dog bite with protective gear; and (5) Oleoresin Capsicum spray to the face with eyes shielded. The SFST was administered and graded by a qualified LEO. After the SFST, the volunteer entered their scenario and was then administered another SFST. Data were analyzed using descriptive statistics. SFST performance was compared before and after using chi-square tests. Fifty-seven subjects enrolled. Three received a single-point penalty during one component of the three-component SFST pre-scenario. No subject received a penalty point in any components of the SFST post-scenario (p = 0.08). This is the first human study to examine the effects of physical resistance, flight, and use of force on the SFST result. We did not detect a difference in the performance of subjects taking the SFST before and after exposure to resistance, flight, or a simulated use of force. © Australian Council for Educational Research 2014.

  9. Ground reaction force comparison of controlled resistance methods to isoinertial loading of the squat exercise - biomed 2010.

    Science.gov (United States)

    Paulus, David C; Reynolds, Michael C; Schilling, Brian K

    2010-01-01

    The ground reaction force during the concentric (raising) portion of the squat exercise was compared to that of isoinertial loading (free weights) for three pneumatically controlled resistance methods: constant resistance, cam force profile, and proportional force control based on velocity. Constant force control showed lower ground reaction forces than isoinertial loading throughout the range of motion (ROM). The cam force profile exhibited slightly greater ground reaction forces than isoinertial loading at 10 and 40% ROM with fifty-percent greater loading at 70% ROM. The proportional force control consistently elicited greater ground reaction force than isoinertial loading, which progressively ranged from twenty to forty percent increase over isoinertial loading except for being approximately equal at 85% ROM. Based on these preliminary results, the proportional control shows the most promise for providing loading that is comparable in magnitude to isoinertial loading. This technology could optimize resistance exercise for sport-specific training or as a countermeasure to atrophy during spaceflight.

  10. Planetary Vital Signs

    Science.gov (United States)

    Kennel, Charles; Briggs, Stephen; Victor, David

    2016-07-01

    The climate is beginning to behave in unusual ways. The global temperature reached unprecedented highs in 2015 and 2016, which led climatologists to predict an enormous El Nino that would cure California's record drought. It did not happen the way they expected. That tells us just how unreliable temperature has become as an indicator of important aspects of climate change. The world needs to go beyond global temperature to a set of planetary vital signs. Politicians should not over focus policy on one indicator. They need to look at the balance of evidence. A coalition of scientists and policy makers should start to develop vital signs at once, since they should be ready at the entry into force of the Paris Agreement in 2020. But vital signs are only the beginning. The world needs to learn how to use the vast knowledge we will be acquiring about climate change and its impacts. Is it not time to use all the tools at hand- observations from space and ground networks; demographic, economic and societal measures; big data statistical techniques; and numerical models-to inform politicians, managers, and the public of the evolving risks of climate change at global, regional, and local scales? Should we not think in advance of an always-on social and information network that provides decision-ready knowledge to those who hold the responsibility to act, wherever they are, at times of their choosing?

  11. Usefulness of phrenic latency and forced vital capacity in patients with ALS with latent respiratory dysfunction.

    Science.gov (United States)

    Kwon, Soonwook; Min, Ju-Hong; Cho, Hye-Jin; Joo, Byung-Euk; Cho, Eun Bin; Seok, Jin Myoung; Kim, Min-Ji; Kim, Byoung Joon

    2015-07-01

    The pulmonary function test (PFT) is a non-invasive and easily available technique to assess respiratory function in patients with amyotrophic lateral sclerosis (ALS); however, patients with dyspnea sometimes show normal PFT findings. Herein, we investigated whether phrenic nerve conduction study (NCS) and PFT are useful to evaluate respiratory function of patients with ALS with normal value ranges in the PFT. We prospectively enrolled 34 patients with definite or probable ALS, who showed FVC (%) ⩾80 of predicted and 78 healthy subjects. PFT and phrenic NCS were performed with the measurement of forced vital capacity (FVC, %), forced expiratory volumes in 1s (FEV1, %), FEV1/FCV ratio (%), and phrenic compound muscle action potential amplitude, and latency. Compared to healthy controls, ALS patients showed delayed phrenic nerve latency and the decrease of FVC (%) (p=0.006 and pphrenic latency (AUC=0.7655) and FVC (%) (AUC=0.8239) discriminated ALS patients from healthy subjects. We demonstrated that ALS patients had early respiratory dysfunction, despite normal PFT findings. Phrenic latency and FVC (%) can be helpful to discriminate ALS patients with latent respiratory dysfunction from healthy subjects. Copyright © 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  12. CDC Vital Signs: HIV Among Youth in the US

    Science.gov (United States)

    ... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

  13. Forced removals and migration: a theology of resistance and liberation in South Africa

    Directory of Open Access Journals (Sweden)

    Kgatla, Selaelo T.

    2013-05-01

    Full Text Available This paper investigates the intensification of the scope of migrant theology by forced removals in the 1960s and 1970s in South Africa. Forced removals in South Africa were carried out by the white government, especially in the late 1950s and 1960s, with the support of the white churches (particularly white Afrikaans churches underpinned by a series of laws which entrenched racial segregation and inequality and which led to millions of black peoples being forced to leave their ancestral land and white cities to live in barren and overcrowded places. The policy of forced removals accompanied by its resultant reprisals led to a mass exodus of many black people going to settle in the neighbouring countries either to join the arms struggle or further their studies abroad. Those who remained in the country were forced to resist the policy either through violent protest or peaceful resistance. The policy led to black people developing theologies of survival in the country of their birth since they were exposed to a condition of poverty, exploitation and alienation from their cultural heritage, while ensuring exclusive privileges to whites in the country. The paper seeks to investigate how the migrants developed a theology of resistance amidst their dislocation and the heavy-handedness of the government.

  14. Vital Signs – Making Health Care Safer

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the March 2013 CDC Vital Signs report, which discusses lethal infections from carbapenem-resistant Enterobacteriaceae, or CRE, germs and ways health care providers can help stop CRE infections.

  15. CDC Vital Signs: Adult Seat Belt Use in the US

    Science.gov (United States)

    ... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

  16. Self-Centering Seismic Lateral Force Resisting Systems: High Performance Structures for the City of Tomorrow

    Directory of Open Access Journals (Sweden)

    Nathan Brent Chancellor

    2014-09-01

    Full Text Available Structures designed in accordance with even the most modern buildings codes are expected to sustain damage during a severe earthquake; however; these structures are expected to protect the lives of the occupants. Damage to the structure can require expensive repairs; significant business downtime; and in some cases building demolition. If damage occurs to many structures within a city or region; the regional and national economy may be severely disrupted. To address these shortcomings with current seismic lateral force resisting systems and to work towards more resilient; sustainable cities; a new class of seismic lateral force resisting systems that sustains little or no damage under severe earthquakes has been developed. These new seismic lateral force resisting systems reduce or prevent structural damage to nonreplaceable structural elements by softening the structural response elastically through gap opening mechanisms. To dissipate seismic energy; friction elements or replaceable yielding energy dissipation elements are also included. Post-tensioning is often used as a part of these systems to return the structure to a plumb; upright position (self-center after the earthquake has passed. This paper summarizes the state-of-the art for self-centering seismic lateral force resisting systems and outlines current research challenges for these systems.

  17. Gyrokinetic electron acceleration in the force-free corona with anomalous resistivity

    OpenAIRE

    Arzner, Kaspar; Vlahos, Loukas

    2006-01-01

    We numerically explore electron acceleration and coronal heating by dissipative electric fields. Electrons are traced in linear force-free magnetic fields extrapolated from SOHO/MDI magnetograms, endowed with anomalous resistivity ($\\eta$) in localized dissipation regions where the magnetic twist $\

  18. Resistance training intensity and volume affect changes in rate of force development in resistance-trained men.

    Science.gov (United States)

    Mangine, Gerald T; Hoffman, Jay R; Wang, Ran; Gonzalez, Adam M; Townsend, Jeremy R; Wells, Adam J; Jajtner, Adam R; Beyer, Kyle S; Boone, Carleigh H; Miramonti, Amelia A; LaMonica, Michael B; Fukuda, David H; Ratamess, Nicholas A; Stout, Jeffrey R

    2016-12-01

    To compare the effects of two different resistance training programs, high intensity (INT) and high volume (VOL), on changes in isometric force (FRC), rate of force development (RFD), and barbell velocity during dynamic strength testing. Twenty-nine resistance-trained men were randomly assigned to either the INT (n = 15, 3-5 RM, 3-min rest interval) or VOL (n = 14, 10-12 RM, 1-min rest interval) training group for 8 weeks. All participants completed a 2-week preparatory phase prior to randomization. Measures of barbell velocity, FRC, and RFD were performed before (PRE) and following (POST) the 8-week training program. Barbell velocity was determined during one-repetition maximum (1RM) testing of the squat (SQ) and bench press (BP) exercises. The isometric mid-thigh pull was used to assess FRC and RFD at specific time bands ranging from 0 to 30, 50, 90, 100, 150, 200, and 250 ms. Analysis of covariance revealed significant (p velocity. Results indicate that INT is more advantageous than VOL for improving FRC and RFD, while changes in barbell velocity during dynamic strength testing are similarly improved by both protocols in resistance-trained men.

  19. 76 FR 63927 - Interagency Task Force on Antimicrobial Resistance (ITFAR): An Update on A Public Health Action...

    Science.gov (United States)

    2011-10-14

    ... Task Force on Antimicrobial Resistance (ITFAR): An Update on A Public Health Action Plan to Combat... outlined in A Public Health Action Plan to Combat Antimicrobial Resistance (Action Plan) and solicit... (AR) in recognition of the increasing importance of AR as a public health threat. The Task Force is co...

  20. Vitality of optical vortices (Presentation)

    CSIR Research Space (South Africa)

    Roux, FS

    2014-02-01

    Full Text Available stream_source_info Roux3_2014.pdf.txt stream_content_type text/plain stream_size 3018 Content-Encoding UTF-8 stream_name Roux3_2014.pdf.txt Content-Type text/plain; charset=UTF-8 Title Vitality of optical vortices F Stef... Roux Presented at Complex Light and Optical Force VIII SPIE Photonics West 2014 Moscone Center, San Francisco, California USA 5 February 2014 CSIR National Laser Centre, Pretoria, South Africa – p. 1/11 Speckle Amplitude Phase – p. 2/11 Vortex...

  1. CDC Vital Signs-Communication Can Save Lives

    Centers for Disease Control (CDC) Podcasts

    2015-08-04

    This podcast is based on the August 2015 CDC Vital Signs report. Antibiotic-resistant germs cause at least 23,000 deaths each year. Learn how public health authorities and health care facilities can work together to save lives.  Created: 8/4/2015 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 8/4/2015.

  2. Resistance to moment-normal force interaction of I-shaped steel sections

    NARCIS (Netherlands)

    Rombouts, I.M.J.; Snijder, H.H.; Dekker, R.W.A.; Teeuwen, P.A.

    2016-01-01

    This paper describes the assessment of the EN 1993-1-1 design rules for cross-section resistance to moment-normal force interaction (M-Ninteraction). Besides the fact that the Eurocode design rules showunconservative predictions of the reduced plastic moment capacity for the presence of relatively

  3. CDC Vital Signs: Heart Age - Is Your Heart Older Than You?

    Science.gov (United States)

    ... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

  4. CDC Vital Signs: Making Health Care Safer -- Think Sepsis. Time Matters.

    Science.gov (United States)

    ... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

  5. Analysis of the resistive force in fluid flow through porous media

    International Nuclear Information System (INIS)

    Thirriot, C.; Cohen, A.M.S.; Massarani, G.; Cohen, B.M.S.

    1976-01-01

    The resistive term appearing in the equation of motion for a fluid flowing through a porous medium is analyzed. This term represents the interactive force between the fluid and the solid mesh. The analysis was done starting with a simple constitutive equation with the help of large number of experimental data points, both with consolidated and non-consolidated porous media. It was found that in almost all cases the resistive term can be adequately expressed in the vetorial from of Forchheimer's quadratic equation [pt

  6. Multilayer Steel Materials Deformation Resistance and Roll Force Measurement

    Directory of Open Access Journals (Sweden)

    A. G. Kolesnikov

    2014-01-01

    Full Text Available To create new types of cars, raise their reliability, gain operational life, and decrease in metal consumption of products it is necessary to improve mechanical, physical, and also special properties of the constructional materials applied in mechanical engineering. Presently, there are intensive researches and developments under way to create materials with ultrafine-grained structure (the sizes of grains in their crystal lattice make less than 1 micron in one of the measurements.BMSTU developed a manufacturing technology of multilayer steel sheets with steady ultrafine-grained structure based on the multiple hot rolling of billet as a composition consisting of the alternating metal sheets. A principled condition for implementation of such technology is existence of different crystallographic modifications in the adjoining sheets of the composition at specified temperature of rolling.Power parameters of rolling are important technical characteristics of the process. Usually, to determine a deformation resistance value when rolling the diverse multilayer materials, is used the actual resistance value averaging in relation to the components of the composition. The aim of this work is a comparative analysis of known calculated dependences with experimental data when rolling the 100-layer samples. Objects of research were the 100-layer compositions based on the alternating layers of steel 08H18N10 and U8.Experimental samples represented the vacuumized capsules with height, width, and length of 53 mm x 53 mm x 200 mm, respectively, in which there were the 100-layer packs from sheets, each of 0.5 mm, based on the composition of steels (U8+08H18N10. Rolling was made on the double-high mill with rolls of 160 mm in diameter during 19 passes to the thickness of 7 mm with the speed of 0,1 m/s. Relative sinking in each pass was accepted to be equal 10±2,5%. Rolling forces were measured by the strain-gauging method using the measuring cells, located under

  7. A Simple Measure to Assess Hyperinflation and Air Trapping: 1-Forced Expiratory Volume in Three Second / Forced Vital Capacity

    Directory of Open Access Journals (Sweden)

    Sermin Börekçi

    2017-04-01

    Full Text Available Background: Several recent studies have suggested that 1 minus-forced expiratory volume expired in 3 seconds / forced vital capacity (1-FEV3/FVC may be an indicator of distal airway obstruction and a promising measure to evaluate small airways dysfunction. Aims: To investigate the associations of 1-FEV3/FVC with the spirometric measures and lung volumes that assess small airways dysfunction and reflects hyperinflation and air trapping. Study Design: Retrospective cross-sectional study. Methods: Retrospective assessment of a total of 1110 cases who underwent body plethysmographic lung volume estimations between a time span from 2005 to 2012. Patients were assigned into two groups: firstly by FEV1/FVC (FEV1/FVC <70% vs. FEV1/FVC ≥70%; secondly by FEV3/FVC < lower limits of normal (LLN (FEV3/FVC < LLN vs. FEV3/FVC ≥ LLN. Spirometric indices and lung volumes measured by whole-body plethysmography were compared in groups. Also the correlation of spirometric indices with measured lung volumes were assessed in the whole-study population and in subgroups stratified according to FEV1/FVC and FEV3/FVC. Results: Six hundred seven (54.7% were male and 503 (45.3% were female, with a mean age of 52.5±15.6 years. Mean FEV3/FVC and 1-FEV3/FVC were 87.05%, 12.95%, respectively. The mean 1-FEV3/FVC was 4.9% in the FEV1/FVC ≥70% group (n=644 vs. 24.1% in the FEV1/FVC <70% group (n=466. A positive correlation was found between 1-FEV3/FVC and residual volume (r=0.70; p<0.0001, functional residual capacity-pleth (r=0.61; p<0.0001, and total lung capacity (r=0.47; p<0.0001. 1-FEV3/FVC was negatively correlated with forced expiratory flow25-75 (r=−0.84; p<0.0001. The upper limit of 95% confidence interval for 1-FEV3/FVC was 13.7%. 1-FEV3/FVC showed significant correlations with parameters of air trapping and hyperinflation measured by whole-body plethysmography. Importantly, these correlations were higher in study participants with FEV1/FVC <70% or FEV3/FVC

  8. Temporal step fluctuations on a conductor surface: electromigration force, surface resistivity and low-frequency noise

    International Nuclear Information System (INIS)

    Williams, E D; Bondarchuk, O; Tao, C G; Yan, W; Cullen, W G; Rous, P J; Bole, T

    2007-01-01

    Scattering of charge carriers from surface structures will become an increasing factor in the resistivity as the structure decreases in size to the nanoscale. The effects of scattering at the most basic surface defect, a kink in a step edge, are here analyzed using the continuum step model. Using a Langevin analysis, it has been shown that the electromigration force on the atoms at the step edge causes changes in the temporal evolution of the step-edge. For an electromigration force acting perpendicular to the average step edge and mass-transport dominated by step-edge diffusion, significant deviations from the usual t 1/4 scaling of the displacement correlation function occur dependent on a critical time τ and the direction of the force relative to the step edge (i.e. uphill or downhill). Experimental observations of step fluctuations on Ag(111) show the predicted changes among step fluctuations without current, and with current in the up- and down-hill directions for a current density of order 10 5 A cm -2 . The results yield the magnitude of the electromigration force acting on kinked sites at the step-edge. This in turn yields the contribution of the fluctuating steps to the surface resistivity, which exceeds 1% of the bulk resistivity as wire diameters decrease below 10s of nanometres. The temporal fluctuations of kink density can thus also be related to resistivity noise. Relating the known fluctuation spectrum of the step displacements to fluctuations in their lengths, the corresponding resistivity noise is predicted to show spectral signatures of ∼f -1/2 for step fluctuations governed by random attachment/detachment, and ∼f -3/4 for step fluctuations governed by step-edge diffusion

  9. Indexes of the common reed's seed vitality from water-bodies of the Chernobyl exclusive zone

    International Nuclear Information System (INIS)

    Yavnuk, A.A.; Shevtsova, N.L.; Gudkov, D.I.; Levchenko, Ya.I.

    2010-01-01

    Investigation of the common reed's seed vitality (vegetation of 2009) from flood-plain water-bodies with different level of radionuclide contamination was carried out. Decrease in indexes of seed's vitality and abnormalities in seed dynamic sprouting was noticed. Dose-response relationship of germination, germinating force, survival rate of seeds of plants was determined. (authors)

  10. Force and power characteristics of a resistive exercise device for use in space

    Science.gov (United States)

    Berg, Hans E.; Tesch, Per A.

    We have developed a non-gravity dependent mechanical device, which provides resistance during coupled concentric and eccentric muscle actions, through the inertia of a spinning fly-wheel (Fly-Wheel Ergometry; FWE). Our research shows that lower-limb FWE exercise can produce forces and thus muscular stress comparable to what is typical of advanced resistance training using free weights. FWE also offers greater training stimuli during eccentric relative to concentric muscle actions, as evidenced by force and electromyographic (EMG) measurements. Muscle use of specific muscle groups, as assessed by the exercise-induced contrast shift of magnetic resonance images, is similar during lower-limb FWE and the barbell squat. Unlike free-weight exercise, FWE allows for maximal voluntary effort in each repetition of an exercise bout. Likewise, FWE exercise, not unassisted free-weight exercise, produces eccentric "overload". Collectively, the inherent features of this resistive exercise device and the results of the physiological evaluations we have performed, suggest that resistance exercise using FWE could be used as an effective exercise counter-measure in space. The flywheel principle can be employed to any exercise configuration and designed into a compact device allowing for exercises stressing those muscles and bone structures, which are thought to be most affected by long-duration spaceflight.

  11. DETERMINATION THE PERMISSIBLE FORCES IN ASSESSING THE LIFT RESISTANT FACTOR OF FREIGHT CARS IN TRAINS

    Directory of Open Access Journals (Sweden)

    A. O. Shvets

    2016-02-01

    Full Text Available Purpose. In the analytical research are considered: 1 relationships between the longitudinal force acting on the car in the train; 2 lateral and vertical forces of interaction in the contact zone «wheel – rail»; 3 dynamic indicators of cars with the magnitude of the car lift resistance factor; 4 obtaining of the dependencies between them. Methodology. The study was conducted by an analytical method assessing the sustainability of the freight car when driving at different speeds on the straight and curved track sections. Findings. In the process of studying the motion of the train, in the investigation of transport events, as well as during the training on the simulator operator, to assess the actions of the driver, the values of the longitudinal forces in the inter car connections are used. To calculate the longitudinal compressive forces, acting on the car, in which car lift resistance factor will be equal to the allowable value (critical force. To assess the impact on the value of the longitudinal force speed, coefficients of the vertical and horizontal dynamics, as well as the wind load on the side surface of the car body are the results of calculations of motion of the empty gondola car, model № 12-532 curve radius of 250 m with a rise of 150 mm and a transverse run of body of car frame relative to the track axis of the guide section 50 mm. Originality. In this study, the technique of determining the longitudinal compressive force was shown, that is somewhat different from the standard. So, as well as assessing the impact on it the speed of rolling coefficients of vertical and horizontal dynamics and wind load on the side surface of the car body. Practical value. The authors developed proposals on the enhancement of existing methods for determining the value of the longitudinal compressive forces acting on the car in which the safety value of the car lift resistance factor will be equal to the allowable value. It will evaluate the

  12. Vital Signs – Making Health Care Safer

    Centers for Disease Control (CDC) Podcasts

    2013-03-05

    This podcast is based on the March 2013 CDC Vital Signs report, which discusses lethal infections from carbapenem-resistant Enterobacteriaceae, or CRE, germs and ways health care providers can help stop CRE infections.  Created: 3/5/2013 by Centers for Disease Control and Prevention (CDC).   Date Released: 3/5/2013.

  13. Forced vital capacity and not central chemoreflex predicts maximal hyperoxic breath-hold duration in elite apneists.

    Science.gov (United States)

    Bain, Anthony R; Barak, Otto F; Hoiland, Ryan L; Drvis, Ivan; Bailey, Damian M; Dujic, Zeljko; Mijacika, Tanja; Santoro, Antoinette; DeMasi, Daniel K; MacLeod, David B; Ainslie, Philip N

    2017-08-01

    The determining mechanisms of a maximal hyperoxic apnea duration in elite apneists have remained unexplored. We tested the hypothesis that maximal hyperoxic apnea duration in elite apneists is related to forced vital capacity (FVC) but not the central chemoreflex (for CO 2 ). Eleven elite apneists performed a maximal dry static-apnea with prior hyperoxic (100% oxygen) pre-breathing, and a central chemoreflex test via a hyperoxic re-breathing technique (hyperoxic-hypercapnic ventilatory response: HCVR); expressed as the increase in ventilation (pneumotachometry) per increase in arterial CO 2 tension (PaCO 2 ; radial artery). FVC was assessed using standard spirometry. Maximal apnea duration ranged from 807 to 1262s (mean=1034s). Average HCVR was 2.0±1.2Lmin -1 mmHg -1 PaCO 2 . The hyperoxic apnea duration was related to the FVC (r 2 =0.45, p0.05). These findings were interpreted to suggest that during a hyperoxic apnea, a larger initial lung volume prolongs the time before reaching intolerable discomfort associated with pending lung squeeze, while CO 2 sensitivity has little impact. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Energía vital. La corriente de Relaciones

    Directory of Open Access Journals (Sweden)

    Stephen Gudeman

    2013-07-01

    Full Text Available Vital energy' is a central idea in the economies of Panama and Colombia. Known as 'strength' or 'force', and assembled from the environment, this current connects all activities in the local economies and establishes relationships, from kin to strangers. Humans compose vital energy, but its sources are limited, and it is expended in use. Its availability is a gift from God and part of the unpredictable fortune that everyone faces. This economy exhibits a contrast between a social current and a market currency. It offers a materialist perspective, provides a critique of standard economics, suggests that sharing rather than reciprocity or rational choice is the 'fundamental' economic practice, and shows how an economy may be a kind of ritual legitimated by a belief in divine power that is displayed through personal fortune.

  15. Vitalism, purpose and superstition.

    Science.gov (United States)

    Lindeman, Marjaana; Saher, Marieke

    2007-02-01

    Developmental studies have shown that children assign purpose to objects more liberally than adults, and that they explain biological processes in terms of vitalistic causality. This study tested the hypothesis that similar misconceptions can be found among superstitious adults. The results from 116 superstitious and 123 sceptical individuals showed that more than sceptics, superstitious individuals attributed purpose to objects, and explained biological processes in terms of organ intentionality and energy transmission. In addition, they thought of energy as a vital force, attributing life and mental properties to it. These conceptual confusions were positively associated to all types of superstitions as well as belief in alternative medicine. The results support the argument that category mistakes and ontological confusions underlie superstitious and vitalistic thinking.

  16. Transition of torque pattern in undulatory locomotion due to wave number variation in resistive force dominated media

    Science.gov (United States)

    Ding, Yang; Ming, Tingyu

    2016-11-01

    In undulatory locomotion, torque (bending moment) is required along the body to overcome the external forces from environments and bend the body. Previous observations on animals using less than two wavelengths on the body showed such torque has a single traveling wave pattern. Using resistive force theory model and considering the torque generated by external force in a resistive force dominated media, we found that as the wave number (number of wavelengths on the locomotor's body) increases from 0.5 to 1.8, the speed of the traveling wave of torque decreases. When the wave number increases to 2 and greater, the torque pattern transits from a single traveling wave to a two traveling waves and then a complex pattern that consists two wave-like patterns. By analyzing the force distribution and its contribution to the torque, we explain the speed decrease of the torque wave and the pattern transition. This research is partially supported by the Recruitment Program of Global Young Experts (China).

  17. Improving the contact resistance at low force using gold coated carbon nanotube surfaces

    Science.gov (United States)

    McBride, J. W.; Yunus, E. M.; Spearing, S. M.

    2010-04-01

    Investigations to determine the electrical contact performance under repeated cycles at low force conditions for carbon-nanotube (CNT) coated surfaces were performed. The surfaces under investigation consisted of multi-walled CNT synthesized on a silicon substrate and coated with a gold film. These planar surfaces were mounted on the tip of a PZT actuator and contacted with a plated Au hemispherical probe. The dynamic applied force used was 1 mN. The contact resistance (Rc) of these surfaces was investigated with the applied force and with repeated loading cycles performed for stability testing. The surfaces were compared with a reference Au-Au contact under the same experimental conditions. This initial study shows the potential for the application of gold coated CNT surfaces as an interface in low force electrical contact applications.

  18. Association of Forced Vital Capacity with the Developmental Gene NCOR2.

    Directory of Open Access Journals (Sweden)

    Cosetta Minelli

    Full Text Available Forced Vital Capacity (FVC is an important predictor of all-cause mortality in the absence of chronic respiratory conditions. Epidemiological evidence highlights the role of early life factors on adult FVC, pointing to environmental exposures and genes affecting lung development as risk factors for low FVC later in life. Although highly heritable, a small number of genes have been found associated with FVC, and we aimed at identifying further genetic variants by focusing on lung development genes.Per-allele effects of 24,728 SNPs in 403 genes involved in lung development were tested in 7,749 adults from three studies (NFBC1966, ECRHS, EGEA. The most significant SNP for the top 25 genes was followed-up in 46,103 adults (CHARGE and SpiroMeta consortia and 5,062 children (ALSPAC. Associations were considered replicated if the replication p-value survived Bonferroni correction (p<0.002; 0.05/25, with a nominal p-value considered as suggestive evidence. For SNPs with evidence of replication, effects on the expression levels of nearby genes in lung tissue were tested in 1,111 lung samples (Lung eQTL consortium, with further functional investigation performed using public epigenomic profiling data (ENCODE.NCOR2-rs12708369 showed strong replication in children (p = 0.0002, with replication unavailable in adults due to low imputation quality. This intronic variant is in a strong transcriptional enhancer element in lung fibroblasts, but its eQTL effects could not be tested due to low imputation quality in the eQTL dataset. SERPINE2-rs6754561 replicated at nominal level in both adults (p = 0.036 and children (p = 0.045, while WNT16-rs2707469 replicated at nominal level only in adults (p = 0.026. The eQTL analyses showed association of WNT16-rs2707469 with expression levels of the nearby gene CPED1. We found no statistically significant eQTL effects for SERPINE2-rs6754561.We have identified a new gene, NCOR2, in the retinoic acid signalling pathway pointing

  19. Vital Stats (Vital Statistics Tables and files- Births, Infant Deaths, Fetal Deaths)

    Data.gov (United States)

    U.S. Department of Health & Human Services — VitalStats: A collection of vital statistics products including tables, data files, and reports that allow users to access and examine vital statistics and...

  20. A pathway for hospital librarians: why is it vital?

    Science.gov (United States)

    Tooey, Mary Joan M J

    2009-10-01

    By the mid 2000s, reports of hospital librarians losing jobs and hospital libraries closing were rife. In 2005, Vital Pathways: The Hospital Libraries Project was established by 2005/06 MLA President M.J. Tooey, AHIP, FMLA, to assess the truth of these reports and to study and develop strategies to support hospital librarians. Throughout this long-term project, opportunities were sought to understand the issues more clearly. A steering committee, along with three task forces, was established to carry out the work of the project. The steering committee provided oversight and had responsibility for promoting and marketing the project. The three task forces were responsible for conducting a survey on the status of hospital librarians, determining the involvement of librarians in medical education and accreditation, and researching and writing a document reviewing current and future roles for hospital librarians. Along the way, these responsibilities grew and evolved. After a little more than three years, the Task Force on Vital Pathways for Hospital Librarians Steering Committee presented a final report regarding its accomplishments to the MLA Board of Directors. A sampling of these accomplishments includes the status of hospital librarians survey, a website, a position document with an accompanying executive summary, a short promotional brochure, and a final culminating activity, this symposium. Although these are difficult times for all libraries, hospital librarians and libraries seem particularly affected. In a competitive health care environment that is driven by the bottom line, influenced by real estate hunger, and affected by the belief of hospital administrators that access to health information comes from the Internet and is free, the hospital librarian seems doomed. However, even in these difficult times, there are hospital librarians who are not only surviving, but thriving. Is it because they are entrepreneurial? Opportunistic? Innovative? Flexible? All

  1. FORCE-VELOCITY, IMPULSE-MOMENTUM RELATIONSHIPS: IMPLICATIONS FOR EFFICACY OF PURPOSEFULLY SLOW RESISTANCE TRAINING

    Directory of Open Access Journals (Sweden)

    Brian K. Schilling

    2008-06-01

    Full Text Available The purpose of this brief review is to explain the mechanical relationship between impulse and momentum when resistance exercise is performed in a purposefully slow manner (PS. PS is recognized by ~10s concentric and ~4-10s eccentric actions. While several papers have reviewed the effects of PS, none has yet explained such resistance training in the context of the impulse-momentum relationship. A case study of normal versus PS back squats was also performed. An 85kg man performed both normal speed (3 sec eccentric action and maximal acceleration concentric action and PS back squats over a several loads. Normal speed back squats produced both greater peak and mean propulsive forces than PS action when measured across all loads. However, TUT was greatly increased in the PS condition, with values fourfold greater than maximal acceleration repetitions. The data and explanation herein point to superior forces produced by the neuromuscular system via traditional speed training indicating a superior modality for inducing neuromuscular adaptation

  2. Forced vital capacity predicts morbidity and mortality in adults with repaired tetralogy of Fallot.

    Science.gov (United States)

    Cohen, Katie E; Buelow, Matthew W; Dixon, Jennifer; Brazauskas, Ruta; Cohen, Scott B; Earing, Michael G; Ginde, Salil

    2017-07-01

    Abnormal lung function characterized by a reduced forced vital capacity (FVC) is common in adults with repaired tetralogy of Fallot (TOF) and is associated with previous thoracotomies and sternotomies. The impact of abnormal lung function on clinical outcomes in adult patients with repaired TOF is unclear. The aim of this study was to determine the impact of abnormal lung function on the outcome of hospitalization and death in adults with repaired TOF when analyzed with other traditional cardiac risk factors. Retrospective study of adults with repaired TOF, who underwent spirometry between 2000 and 2014. FVC < 60% of predicted was categorized as moderate-to-severely reduced lung function. Primary outcome measure was the combined clinical endpoint of death, cardiac transplantation, or nonelective hospitalization for primary cardiac or respiratory indication. A total of 122 patients were included. Average age at spirometry testing was 31 ± 10.1 years. FVC was < 60% predicted in 23 (19%) patients. During a mean follow-up period of 3.97 ± 2.65 years, 23 (19%) patients reached the combined clinical outcome of nonelective hospitalization and/or death. FVC < 60% predicted was independently associated with the risk for the combined clinical outcome (RR 6.68 (95% CI 2.49-17.94), P < .001). Abnormal pulmonary function characterized by reduced FVC is common in adults with repaired TOF. Patients with FVC < 60% predicted had a 6 times higher rate of hospitalization and/or death compared to those with FVC ≥ 60%. © 2017 Wiley Periodicals, Inc.

  3. Embryo mechanics: balancing force production with elastic resistance during morphogenesis.

    Science.gov (United States)

    Davidson, Lance A

    2011-01-01

    Morphogenesis requires the spatial and temporal control of embryo mechanics, including force production and mechanical resistance to those forces, to coordinate tissue deformation and large-scale movements. Thus, biomechanical processes play a key role in directly shaping the embryo. Additional roles for embryo mechanics during development may include the patterning of positional information and to provide feedback to ensure the success of morphogenetic movements in shaping the larval body and organs. To understand the multiple roles of mechanics during development requires familiarity with engineering principles of the mechanics of structures, the viscoelastic properties of biomaterials, and the integration of force and stress within embryonic structures as morphogenesis progresses. In this chapter, we review the basic engineering principles of biomechanics as they relate to morphogenesis, introduce methods for quantifying embryo mechanics and the limitations of these methods, and outline a formalism for investigating the role of embryo mechanics in birth defects. We encourage the nascent field of embryo mechanics to adopt standard engineering terms and test methods so that studies of diverse organisms can be compared and universal biomechanical principles can be revealed. Copyright © 2011 Elsevier Inc. All rights reserved.

  4. On the forces that drive and resist deformation of the south-central Mediterranean: a mechanical model study

    Science.gov (United States)

    Nijholt, Nicolai; Govers, Rob; Wortel, Rinus

    2018-04-01

    The geodynamics of the Mediterranean comprises a transitional setting in which slab rollback and plate convergence compete to shape the region. In the central Mediterranean, where the balance of driving and resisting forces changes continuously and rapidly since the Miocene, both kinematic and seismo-tectonic observations display a strong variation in deformation style and, therefore possibly, lithospheric forces. We aim to understand the current kinematics in southern Italy and Sicily in terms of lithospheric forces that cause them. The strong regional variation of geodetic velocities appears to prohibit such simple explanation. We use mechanical models to quantify the deformation resulting from large-scale Africa-Eurasia convergence, ESE retreat of the Calabrian subduction zone, pull by the Aegean slab, and regional variations in gravitational potential energy (topography). A key model element is the resistance to slip on major regional fault zones. We show that geodetic velocities, seismicity and sense of slip on regional faults can be understood to result from lithospheric forces. Our most important new finding is that regional variations in resistive tractions are required to fit the observations, with notably very low tractions on the Calabrian subduction contact, and a buildup towards a significant earthquake in the Calabrian fore-arc. We also find that the Calabrian net slab pull force is strongly reduced (compared to the value possible in view of the slab's dimensions) and that trench suction tractions are negligible. Such very small contributions to the present-day force balance in the south-central Mediterranean suggest that the Calabrian arc is now further transitioning towards a setting dominated by Africa-Eurasia plate convergence, whereas during the past 30 Myrs slab retreat continually was the dominant factor.

  5. Assessment of Structural Resistance of building 4862 to Earthquake and Tornado Forces [SEC 1 and 2

    International Nuclear Information System (INIS)

    METCALF, I.L.

    1999-01-01

    This report presents the results of work done for Hanford Engineering Laboratory under contract Y213-544-12662. LATA performed an assessment of building 4862 resistance to earthquake and tornado forces

  6. Assessment of Structural Resistance of building 4862 to Earthquake and Tornado Forces [SEC 1 and 2

    Energy Technology Data Exchange (ETDEWEB)

    METCALF, I.L.

    1999-12-06

    This report presents the results of work done for Hanford Engineering Laboratory under contract Y213-544-12662. LATA performed an assessment of building 4862 resistance to earthquake and tornado forces.

  7. Evaluation of the nanotube intrinsic resistance across the tip-carbon nanotube-metal substrate junction by Atomic Force Microscopy.

    Science.gov (United States)

    Dominiczak, Maguy; Otubo, Larissa; Alamarguy, David; Houzé, Frédéric; Volz, Sebastian; Noël, Sophie; Bai, Jinbo

    2011-04-14

    Using an atomic force microscope (AFM) at a controlled contact force, we report the electrical signal response of multi-walled carbon nanotubes (MWCNTs) disposed on a golden thin film. In this investigation, we highlight first the theoretical calculation of the contact resistance between two types of conductive tips (metal-coated and doped diamond-coated), individual MWCNTs and golden substrate. We also propose a circuit analysis model to schematize the «tip-CNT-substrate» junction by means of a series-parallel resistance network. We estimate the contact resistance R of each contribution of the junction such as Rtip-CNT, RCNT-substrate and Rtip-substrate by using the Sharvin resistance model. Our final objective is thus to deduce the CNT intrinsic radial resistance taking into account the calculated electrical resistance values with the global resistance measured experimentally. An unwished electrochemical phenomenon at the tip apex has also been evidenced by performing measurements at different bias voltages with diamond tips. For negative tip-substrate bias, a systematic degradation in color and contrast of the electrical cartography occurs, consisting of an important and non-reversible increase of the measured resistance. This effect is attributed to the oxidation of some amorphous carbon areas scattered over the diamond layer covering the tip. For a direct polarization, the CNT and substrate surface can in turn be modified by an oxidation mechanism.

  8. Ground reaction force comparison of bilateral symmetry with pneumatic resistance squat device and free weights - biomed 2009.

    Science.gov (United States)

    Paulus, David C; Schilling, Brian K

    2009-01-01

    The unloading of spaceflight leads to bone and muscle atrophy, and a pneumatic resistance squat exercise countermeasure has the potential to provide optimized controllable resistance in a lightweight and compact configuration. However each end of the barbell in the proposed device is connected to a separate resistance cylinder which could lead to bilaterally asymmetric loading. Therefore, the purpose of the study is to compare the unilateral ground reaction forces (GRF) of the new squat device compared to free weights. Four previously trained men (mean +/- SD; age = 20+/-2 years, body mass = 99+/-18 kg) performed three sets of three repetitions of maximal exertion squat exercises with pneumatically controlled constant resistance and free weights each with a resistance level set to half of the body weight of each subject. Unilateral GRF data for each lifting modality at the negative to positive transition of the squat exercise was measured with a force plate under each foot. The pneumatic resistance GRF (N; mean +/- SD) was 749+/-114 on the left leg and 786+/-123 on the right leg and the free weight GRF was 786+/-114 left and 861+/-111 right resulting in a 5% difference between left and right GRF with pneumatics and 9% difference with free weights. The correlation coefficient between left and right GRF was 0.92 with pneumatics and 0.80 with free weights. Because the pneumatic device elicited more bilaterally symmetric GRF than traditional free weights, the separate resistance cylinders are an acceptable design configuration.

  9. Longitudinal modeling to predict vital capacity in amyotrophic lateral sclerosis.

    Science.gov (United States)

    Jahandideh, Samad; Taylor, Albert A; Beaulieu, Danielle; Keymer, Mike; Meng, Lisa; Bian, Amy; Atassi, Nazem; Andrews, Jinsy; Ennist, David L

    2018-05-01

    Death in amyotrophic lateral sclerosis (ALS) patients is related to respiratory failure, which is assessed in clinical settings by measuring vital capacity. We developed ALS-VC, a modeling tool for longitudinal prediction of vital capacity in ALS patients. A gradient boosting machine (GBM) model was trained using the PRO-ACT (Pooled Resource Open-access ALS Clinical Trials) database of over 10,000 ALS patient records. We hypothesized that a reliable vital capacity predictive model could be developed using PRO-ACT. The model was used to compare FVC predictions with a 30-day run-in period to predictions made from just baseline. The internal root mean square deviations (RMSD) of the run-in and baseline models were 0.534 and 0.539, respectively, across the 7L FVC range captured in PRO-ACT. The RMSDs of the run-in and baseline models using an unrelated, contemporary external validation dataset (0.553 and 0.538, respectively) were comparable to the internal validation. The model was shown to have similar accuracy for predicting SVC (RMSD = 0.562). The most important features for both run-in and baseline models were "Baseline forced vital capacity" and "Days since baseline." We developed ALS-VC, a GBM model trained with the PRO-ACT ALS dataset that provides vital capacity predictions generalizable to external datasets. The ALS-VC model could be helpful in advising and counseling patients, and, in clinical trials, it could be used to generate virtual control arms against which observed outcomes could be compared, or used to stratify patients into slowly, average, and rapidly progressing subgroups.

  10. Report of the Error and Emittance Task Force on the superconducting super collider: Part 1, Resistive machines

    International Nuclear Information System (INIS)

    1993-10-01

    A review of the design and specifications of the resistive accelerators in the SSC complex was conducted during the past year. This review was initiated in response to a request from the SSC Project Manager. The Error and Emittance Task Force was created October 30, 1992, and charged with reviewing issues associated with the specification of errors and tolerances throughout the injector chain and in the Collider, and to optimize the global error budget. Effects which directly impact the emittance budget were of prime importance. The Task Force responded to three charges: Examination of the resistive accelerators and their injection and extraction systems; examination of the connecting beamlines and the overall approach taken in their design; and global filling, timing, and synchronization issues. The High Energy Booster and the Collider were deemed to be sufficiently different from the resistive accelerators that it was decided to treat them as a separate group. They will be the subject of a second part to this report

  11. VARIATION IN RESISTIVE FORCE SELECTION DURING BRIEF HIGH INTENSITY CYCLE ERGOMETRY: IMPLICATIONS FOR POWER ASSESSMENT AND PRODUCTION IN ELITE KARATE PRACTITIONERS

    Directory of Open Access Journals (Sweden)

    Julien Steven Baker

    2006-07-01

    Full Text Available The purpose of this study was to measure power values generated in elite karate fighters during brief high intensity cycle ergometry when resistive forces were derived from total - body mass (TBM or fat - free mass (FFM. Male international karate practitioners volunteered as participants (n = 11. Body density was calculated using hydrostatic weighing procedures with fat mass ascertained from body density values. Participants were required to pedal maximally on a cycle ergometer (Monark 864 against randomly assigned loads ranging from 70 g·kg-1 - 95 g·kg-1 (using a TBM or FFM protocol for 8 seconds. The resistive force that produced the highest peak power output (PPO for each protocol was considered optimal. Differences (p 0.05 were observed between time to PPO, or heart rate when the TBM and FFM protocols were compared. The findings of this study suggest that when high intensity cycle ergometer resistive forces are derived from FFM, greater peak powers can be obtained consistently in karate athletes. Resistive forces that relate to the active muscle tissue utilised during this type of exercise may need to be explored in preference to protocols that include both lean and fat masses. The findings have implications for both exercise prescription and the evaluation of experimental results concerning karate athletes

  12. Impact of Cutting Forces and Chip Microstructure in High Speed Machining of Carbon Fiber – Epoxy Composite Tube

    Directory of Open Access Journals (Sweden)

    Roy Y. Allwin

    2017-09-01

    Full Text Available Carbon fiber reinforced polymeric (CFRP composite materials are widely used in aerospace, automobile and biomedical industries due to their high strength to weight ratio, corrosion resistance and durability. High speed machining (HSM of CFRP material is needed to study the impact of cutting parameters on cutting forces and chip microstructure which offer vital inputs to the machinability and deformation characteristics of the material. In this work, the orthogonal machining of CFRP was conducted by varying the cutting parameters such as cutting speed and feed rate at high cutting speed/feed rate ranges up to 346 m/min/ 0.446 mm/rev. The impact of the cutting parameters on cutting forces (principal cutting, feed and thrust forces and chip microstructure were analyzed. A significant impact on thrust forces and chip segmentation pattern was seen at higher feed rates and low cutting speeds.

  13. Evaluation of the nanotube intrinsic resistance across the tip-carbon nanotube-metal substrate junction by Atomic Force Microscopy

    Directory of Open Access Journals (Sweden)

    Alamarguy David

    2011-01-01

    Full Text Available Abstract Using an atomic force microscope (AFM at a controlled contact force, we report the electrical signal response of multi-walled carbon nanotubes (MWCNTs disposed on a golden thin film. In this investigation, we highlight first the theoretical calculation of the contact resistance between two types of conductive tips (metal-coated and doped diamond-coated, individual MWCNTs and golden substrate. We also propose a circuit analysis model to schematize the «tip-CNT-substrate» junction by means of a series-parallel resistance network. We estimate the contact resistance R of each contribution of the junction such as R tip-CNT, R CNT-substrate and R tip-substrate by using the Sharvin resistance model. Our final objective is thus to deduce the CNT intrinsic radial resistance taking into account the calculated electrical resistance values with the global resistance measured experimentally. An unwished electrochemical phenomenon at the tip apex has also been evidenced by performing measurements at different bias voltages with diamond tips. For negative tip-substrate bias, a systematic degradation in color and contrast of the electrical cartography occurs, consisting of an important and non-reversible increase of the measured resistance. This effect is attributed to the oxidation of some amorphous carbon areas scattered over the diamond layer covering the tip. For a direct polarization, the CNT and substrate surface can in turn be modified by an oxidation mechanism.

  14. Uniform Selection as a Primary Force Reducing Population Genetic Differentiation of Cavitation Resistance across a Species Range

    Science.gov (United States)

    Lamy, Jean-Baptiste; Bouffier, Laurent; Burlett, Régis; Plomion, Christophe; Cochard, Hervé; Delzon, Sylvain

    2011-01-01

    Background Cavitation resistance to water stress-induced embolism determines plant survival during drought. This adaptive trait has been described as highly variable in a wide range of tree species, but little is known about the extent of genetic and phenotypic variability within species. This information is essential to our understanding of the evolutionary forces that have shaped this trait, and for evaluation of its inclusion in breeding programs. Methodology We assessed cavitation resistance (P 50), growth and carbon isotope composition in six Pinus pinaster populations in a provenance and progeny trial. We estimated the heritability of cavitation resistance and compared the distribution of neutral markers (F ST) and quantitative genetic differentiation (Q ST), for retrospective identification of the evolutionary forces acting on these traits. Results/Discussion In contrast to growth and carbon isotope composition, no population differentiation was found for cavitation resistance. Heritability was higher than for the other traits, with a low additive genetic variance (h2 ns = 0.43±0.18, CVA = 4.4%). Q ST was significantly lower than F ST, indicating uniform selection for P 50, rather than genetic drift. Putative mechanisms underlying QST

  15. Chronic airflow obstruction after successful treatment of multidrug-resistant tuberculosis

    Directory of Open Access Journals (Sweden)

    Anthony L. Byrne

    2017-07-01

    Full Text Available Cross-sectional studies reveal an association between tuberculosis (TB and chronic airflow obstruction, but cannot adequately address confounding. We hypothesised that treated pulmonary TB is an independent risk factor for chronic airflow obstruction. The Pulmones Post TB cohort study enrolled participants from Lima, Peru, aged 10–70 years with a history of drug-susceptible (DS- or multidrug-resistant (MDR-TB who had completed treatment and were clinically cured. Unexposed participants without TB were randomly selected from the same districts. We assessed respiratory symptoms, relevant environmental exposures, and spirometric lung function pre- and post-bronchodilator. In total, 144 participants with DS-TB, 33 with MDR-TB and 161 unexposed participants were fully evaluated. Compared with unexposed participants, MDR-TB patients had lower lung volumes (adjusted mean difference in forced vital capacity −370 mL, 95% CI −644– −97 and post-bronchodilator airflow obstruction (adjusted OR 4.89, 95% CI 1.27–18.78. Participants who had recovered from DS-TB did not have lower lung volumes than unexposed participants, but were more likely to have a reduced forced expiratory volume in 1 s/forced vital capacity ratio <0.70 (adjusted OR 2.47, 95% CI 1.01–6.03. Individuals successfully treated for TB may experience long-lasting sequelae. Interventions facilitating earlier TB treatment and management of chronic respiratory disease should be explored.

  16. Vital Signs: Preventing Antibiotic-Resistant Infections in Hospitals - United States, 2014.

    Science.gov (United States)

    Weiner, Lindsey M; Fridkin, Scott K; Aponte-Torres, Zuleika; Avery, Lacey; Coffin, Nicole; Dudeck, Margaret A; Edwards, Jonathan R; Jernigan, John A; Konnor, Rebecca; Soe, Minn M; Peterson, Kelly; McDonald, L Clifford

    2016-03-11

    Health care-associated antibiotic-resistant (AR) infections increase patient morbidity and mortality and might be impossible to successfully treat with any antibiotic. CDC assessed health care-associated infections (HAI), including Clostridium difficile infections (CDI), and the role of six AR bacteria of highest concern nationwide in several types of health care facilities. During 2014, approximately 4,000 short-term acute care hospitals, 501 long-term acute care hospitals, and 1,135 inpatient rehabilitation facilities in all 50 states reported data on specific infections to the National Healthcare Safety Network. National standardized infection ratios and their percentage reduction from a baseline year for each HAI type, by facility type, were calculated. The proportions of AR pathogens and HAIs caused by any of six resistant bacteria highlighted by CDC in 2013 as urgent or serious threats were determined. In 2014, the reductions in incidence in short-term acute care hospitals and long-term acute care hospitals were 50% and 9%, respectively, for central line-associated bloodstream infection; 0% (short-term acute care hospitals), 11% (long-term acute care hospitals), and 14% (inpatient rehabilitation facilities) for catheter-associated urinary tract infection; 17% (short-term acute care hospitals) for surgical site infection, and 8% (short-term acute care hospitals) for CDI. Combining HAIs other than CDI across all settings, 47.9% of Staphylococcus aureus isolates were methicillin resistant, 29.5% of enterococci were vancomycin-resistant, 17.8% of Enterobacteriaceae were extended-spectrum beta-lactamase phenotype, 3.6% of Enterobacteriaceae were carbapenem resistant, 15.9% of Pseudomonas aeruginosa isolates were multidrug resistant, and 52.6% of Acinetobacter species were multidrug resistant. The likelihood of HAIs caused by any of the six resistant bacteria ranged from 12% in inpatient rehabilitation facilities to 29% in long-term acute care hospitals. Although

  17. Utilizing Forced Vital Capacity to Predict Low Lung Compliance and Select Intraoperative Tidal Volume During Thoracic Surgery.

    Science.gov (United States)

    Hoftman, Nir; Eikermann, Eric; Shin, John; Buckley, Jack; Navab, Kaveh; Abtin, Fereidoun; Grogan, Tristan; Cannesson, Maxime; Mahajan, Aman

    2017-12-01

    Tidal volume selection during mechanical ventilation utilizes dogmatic formulas that only consider a patient's predicted body weight (PBW). In this study, we investigate whether forced vital capacity (FVC) (1) correlates better to total lung capacity (TLC) than PBW, (2) predicts low pulmonary compliance, and (3) provides an alternative method for tidal volume selection. One hundred thirty thoracic surgery patients had their preoperative TLC calculated via 2 methods: (1) pulmonary function test (PFT; TLCPFT) and (2) computed tomography 3D reconstruction (TLCCT). We compared the correlation between TLC and PBW with the correlation between TLC and FVC to determine which was stronger. Dynamic pulmonary compliance was then calculated from intraoperative ventilator data and logistic regression models constructed to determine which clinical measure best predicted low compliance. Ratios of tidal volume/FVC plotted against peak inspiratory pressure were utilized to construct a new model for tidal volume selection. Calculated tidal volumes generated by this model were then compared with those generated by the standard lung-protective formula Vt = 7 cc/kg. The correlation between FVC and TLC (0.82 for TLCPFT and 0.76 for TLCCT) was stronger than the correlation between PBW and TLC (0.65 for TLCPFT and 0.58 for TLCCT). Patients with very low compliance had significantly smaller lung volumes (forced expiratory volume at 1 second, FVC, TLC) and lower diffusion capacity of the lungs for carbon monoxide when compared with patients with normal compliance. An FVC cutoff of 3470 cc was 100% sensitive and 51% specific for predicting low compliance. The proposed equation Vt = FVC/8 significantly reduced calculated tidal volume by a mean of 22.5% in patients with low pulmonary compliance without affecting the mean tidal volume in patients with normal compliance (mean difference 0.9%). FVC is more strongly correlated to TLC than PBW and a cutoff of about 3.5 L can be utilized to predict

  18. Prevalence of Methicillin-Resistant Staphylococcus aureus among ...

    African Journals Online (AJOL)

    Purpose: To determine the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in apparently healthy ... treatment failures is vital. Keywords: Methicillin-resistant Staphylococcus aureus, Nasal swabs, Multidrug resistance, Rational .... defined as resistance to three or more classes of antibiotics other than the ...

  19. Empirical resistive-force theory for slender biological filaments in shear-thinning fluids

    Science.gov (United States)

    Riley, Emily E.; Lauga, Eric

    2017-06-01

    Many cells exploit the bending or rotation of flagellar filaments in order to self-propel in viscous fluids. While appropriate theoretical modeling is available to capture flagella locomotion in simple, Newtonian fluids, formidable computations are required to address theoretically their locomotion in complex, nonlinear fluids, e.g., mucus. Based on experimental measurements for the motion of rigid rods in non-Newtonian fluids and on the classical Carreau fluid model, we propose empirical extensions of the classical Newtonian resistive-force theory to model the waving of slender filaments in non-Newtonian fluids. By assuming the flow near the flagellum to be locally Newtonian, we propose a self-consistent way to estimate the typical shear rate in the fluid, which we then use to construct correction factors to the Newtonian local drag coefficients. The resulting non-Newtonian resistive-force theory, while empirical, is consistent with the Newtonian limit, and with the experiments. We then use our models to address waving locomotion in non-Newtonian fluids and show that the resulting swimming speeds are systematically lowered, a result which we are able to capture asymptotically and to interpret physically. An application of the models to recent experimental results on the locomotion of Caenorhabditis elegans in polymeric solutions shows reasonable agreement and thus captures the main physics of swimming in shear-thinning fluids.

  20. Link between defoliation and light treatments on root vitality of five understory shrubs with different resistance to insect herbivory.

    Science.gov (United States)

    Karolewski, Piotr; Zadworny, Marcin; Mucha, Joanna; Napierała-Filipiak, Anna; Oleksyn, Jacek

    2010-08-01

    Understory shrubs are frequently attacked by insect herbivores. However, very little is known regarding possible interactions between light condition, defoliation (D) and fine root vitality (% live roots) and metabolic activity, and whether different plant strategies (compensation, trade-off and equilibrium) to defoliation depend on individual species light requirements. To explore the response of roots to such conditions, an experiment was established in which we experimentally removed 50% of leaves in 1-year-old seedlings of Sambucus nigra, Cornus sanguinea, Prunus serotina, Frangula alnus and Corylus avellana grown in 15% and full sunlight. On average, defoliation leads to a 15% reduction in fine root (vitality (% live roots). However, a statistically significant reduction in root vitality after defoliation was detected only in those species that are less herbivorized in nature (48% in S. nigra and 5% in C. sanguinea). On average, shade conditions (L) resulted in 18% decline in root vitality, and the effects of defoliation were also 22% higher than for plants grown in full light. Root vitality in both treatments (D and L) was significantly correlated with their dry mass, concentration of total phenol (TPh) and carbon to nitrogen ratio, and negatively correlated with nitrogen, soluble carbohydrates, starch and total non-structural carbohydrates (TNC). To a large extent, root vitality and chemistry varied by species. Higher root vitality was related to higher concentrations of phenolics, more than to N and TNC concentrations. Concentrations of phenolics also differed significantly between defoliated plants and controls. However, in defoliated plants, an increase in TPh was observed only in two species, which belong to two different groups in light requirements and susceptibility to insect grazing (C. sanguinea and P. serotina). This study indicated that higher vitality of roots occurred in species that are characterized by higher insect defoliation under natural

  1. Gradients in fracture force and grazing resistance across canopy layers in seven tropical grass species

    NARCIS (Netherlands)

    Jacobs, A.A.A.; Scheper, J.A.; Benvenutti, M.A.; Gordon, I.J.; Poppi, D.P.; Elgersma, A.

    2013-01-01

    In reproductive swards, stems can act as a barrier that affects the grazing behaviour of ruminant livestock. The barrier effect of stems is closely associated with both the force required to fracture the stems and the density of these stems (in combination, these make up grazing resistance), and

  2. Uniform selection as a primary force reducing population genetic differentiation of cavitation resistance across a species range.

    Directory of Open Access Journals (Sweden)

    Jean-Baptiste Lamy

    Full Text Available BACKGROUND: Cavitation resistance to water stress-induced embolism determines plant survival during drought. This adaptive trait has been described as highly variable in a wide range of tree species, but little is known about the extent of genetic and phenotypic variability within species. This information is essential to our understanding of the evolutionary forces that have shaped this trait, and for evaluation of its inclusion in breeding programs. METHODOLOGY: We assessed cavitation resistance (P(50, growth and carbon isotope composition in six Pinus pinaster populations in a provenance and progeny trial. We estimated the heritability of cavitation resistance and compared the distribution of neutral markers (F(ST and quantitative genetic differentiation (Q(ST, for retrospective identification of the evolutionary forces acting on these traits. RESULTS/DISCUSSION: In contrast to growth and carbon isotope composition, no population differentiation was found for cavitation resistance. Heritability was higher than for the other traits, with a low additive genetic variance (h(2 (ns = 0.43±0.18, CV(A = 4.4%. Q(ST was significantly lower than F(ST, indicating uniform selection for P(50, rather than genetic drift. Putative mechanisms underlying Q(ST

  3. Ethnolinguistic Vitality and Intergroup Processes

    Science.gov (United States)

    Ehala, Martin

    2010-01-01

    The paper argues that ethnolinguistic vitality depends on four crucial social psychological factors: perceived strength differential, intergroup distance, utilitarianism and intergroup discordance. The influence of these factors on the vitality of subordinate and dominant groups is outlined. It is proposed that the vitality of both types of groups…

  4. Partial pulp necrosis caused by excessive orthodontic force

    Directory of Open Access Journals (Sweden)

    Min-Young Kim

    2011-03-01

    Full Text Available As the dental pulp is encased with a rigid, noncompliant shell, changes in pulpal blood flow or vascular tissue pressure can have serious implication for the health of pulp. Numerous studies have demonstrated that orthodontic force application may influence both blood flow and cellular metabolism, leading degenerative and/or inflammatory responses in the dental pulp. The aim of this case report is to present a case about tooth with chronic periapical abscess which showed normal vital responses. Excessive orthodontic force is thought to be the prime cause of partial pulp necrosis. Owing to remaining vital tissue, wrong dianosis can be made, and tooth falsely diagnosed as vital may be left untreated, causing the necrotic tissue to destroy the supporting tissuses. Clinician should be able to utilize various diagnostic tools for the precise diagnosis, and be aware of the endodontic-orthodontic inter-relationship.

  5. Reactor vital equipment determination techniques

    International Nuclear Information System (INIS)

    Bott, T.F.; Thomas, W.S.

    1983-01-01

    The Reactor Vital Equipment Determination Techniques program at the Los Alamos National Laboratory is discussed. The purpose of the program is to provide the Nuclear Regulatory Commission (NRC) with technical support in identifying vital areas at nuclear power plants using a fault-tree technique. A reexamination of some system modeling assumptions is being performed for the Vital Area Analysis Program. A short description of the vital area analysis and supporting research on modeling assumptions is presented. Perceptions of program modifications based on the research are outlined, and the status of high-priority research topics is discussed

  6. Delayed Effect of Blood-Flow-Restricted Resistance Training on Rapid Force Capacity

    DEFF Research Database (Denmark)

    Nielsen, Jakob Lindberg; Frandsen, Ulrik; Prokhorova, Tatyana

    2017-01-01

    of knee extensor exercise (20%1RM) to concentric failure during concurrent BFR of the thigh (100mmHg), while eight work-matched controls (21.9±3.0 years) trained without BFR (CON). Twenty-three training sessions were performed within 19 days. Maximal slow and fast knee joint velocity muscle strength......PURPOSE: The aim of the present study was to investigate the effect and time course of high-frequent low-load resistance training with blood-flow restriction (BFR) on rapid force capacity (i.e. rate of torque development (RTD)). METHODS: Ten male subjects (22.8±2.3 years) performed four sets...... and rapid force capacity (e.g. RTD) as well as evoked twitch contractile parameters was assessed before (Pre) and 5 and 12 days after training (Post5, Post12). Muscle biopsies were obtained Pre, after 8 days (Mid8) and 3 and 10 days post training (Post3, Post10) to examine changes in myofiber area...

  7. Effects of fast-velocity eccentric resistance training on early and late rate of force development

    DEFF Research Database (Denmark)

    Oliveira, Anderson S.C.; Corvino, Rogério Bulhões; Caputo, Fabrizio

    2016-01-01

    This study examined whether short-term maximal resistance training employing fast-velocity eccentric knee extensor actions would induce improvements in maximal isometric torque and rate of force development (RFD) at early (phases (>100 ms) of rising torque. Twenty healthy men were......, no changes in the late phase of incremental RFD were observed in TG. No changes were found in the CG. In summary, we have demonstrated, in active individuals, that a short period of resistance training performed with eccentric fast-velocity isokinetic muscle contractions is able to enhance RFDINC and RFDREL...... assigned to two experimental groups: eccentric resistance training (TG) or control (CG). Participants on the TG trained three days a week for a total of eight weeks. Training consisted of maximal unilateral eccentric knee extensors actions performed at 180°s-1. Maximal isometric knee extensor torque (MVC...

  8. Can Sophie's choice be adequately captured by cold computation of minimizing losses? An fMRI study of vital loss decisions.

    Directory of Open Access Journals (Sweden)

    Qi Li

    Full Text Available The vast majority of decision-making research is performed under the assumption of the value maximizing principle. This principle implies that when making decisions, individuals try to optimize outcomes on the basis of cold mathematical equations. However, decisions are emotion-laden rather than cool and analytic when they tap into life-threatening considerations. Using functional magnetic resonance imaging (fMRI, this study investigated the neural mechanisms underlying vital loss decisions. Participants were asked to make a forced choice between two losses across three conditions: both losses are trivial (trivial-trivial, both losses are vital (vital-vital, or one loss is trivial and the other is vital (vital-trivial. Our results revealed that the amygdala was more active and correlated positively with self-reported negative emotion associated with choice during vital-vital loss decisions, when compared to trivial-trivial loss decisions. The rostral anterior cingulate cortex was also more active and correlated positively with self-reported difficulty of choice during vital-vital loss decisions. Compared to the activity observed during trivial-trivial loss decisions, the orbitofrontal cortex and ventral striatum were more active and correlated positively with self-reported positive emotion of choice during vital-trivial loss decisions. Our findings suggest that vital loss decisions involve emotions and cannot be adequately captured by cold computation of minimizing losses. This research will shed light on how people make vital loss decisions.

  9. 77 FR 58143 - Interagency Task Force on Antimicrobial Resistance (ITFAR): An Update of A Public Health Action...

    Science.gov (United States)

    2012-09-19

    ...-2012-0011] Interagency Task Force on Antimicrobial Resistance (ITFAR): An Update of A Public Health...), Department of Health and Human Services (HHS). ACTION: Notice of public meeting and request for comments... Federal agencies in accomplishing activities outlined in ``A Public Health Action Plan to Combat...

  10. Mechanism of force mode dip-pen nanolithography

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Haijun, E-mail: yanghaijun@sinap.ac.cn, E-mail: swguo@sjtu.edu.cn, E-mail: wanghuabin@cigit.ac.cn [Key Laboratory for Thin Film and Microfabrication of the Ministry of Education, Research Institute of Micro/Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240 (China); Interfacial Water Division and Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, CAS, Shanghai 201800 (China); Xie, Hui; Rong, Weibin; Sun, Lining [State Key Laboratory of Robotics and Systems, Harbin Institute of Technology, Harbin 150080 (China); Wu, Haixia; Guo, Shouwu, E-mail: yanghaijun@sinap.ac.cn, E-mail: swguo@sjtu.edu.cn, E-mail: wanghuabin@cigit.ac.cn [Key Laboratory for Thin Film and Microfabrication of the Ministry of Education, Research Institute of Micro/Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240 (China); Wang, Huabin, E-mail: yanghaijun@sinap.ac.cn, E-mail: swguo@sjtu.edu.cn, E-mail: wanghuabin@cigit.ac.cn [Centre for Tetrahertz Research, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing 400714 (China)

    2014-05-07

    In this work, the underlying mechanism of the force mode dip-pen nanolithography (FMDPN) is investigated in depth by analyzing force curves, tapping mode deflection signals, and “Z-scan” voltage variations during the FMDPN. The operation parameters including the relative “trigger threshold” and “surface delay” parameters are vital to control the loading force and dwell time for ink deposition during FMDPN. A model is also developed to simulate the interactions between the atomic force microscope tip and soft substrate during FMDPN, and verified by its good performance in fitting our experimental data.

  11. Fabrication of robot head module using contact resistance force sensor for human robot interaction and its evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Dong Ki; Kim, Jong Ho [Korea Reserch Institute of Standards and Science, Daejeon (Korea, Republic of); Kwon, Hyun Joon [Univ. of Maryland, Maryland (United States); Kwon, Young Ha [Kyung Hee Univ., Gyunggi Do (Korea, Republic of)

    2012-10-15

    This paper presents a design of a robot head module with touch sensing algorithms that can simultaneously detect contact force and location. The module is constructed with a hemisphere and three sensor units that are fabricated using contact resistance force sensors. The surface part is designed with the hemisphere that measures 300 mm in diameter and 150 mm in height. Placed at the bottom of the robot head module are three sensor units fabricated using a simple screen printing technique. The contact force and the location of the model are evaluated through the calibration setup. The experiment showed that the calculated contact positions almost coincided with the applied load points as the contact location changed with a location error of about {+-}8.67 mm. The force responses of the module were evaluated at two points under loading and unloading conditions from 0 N to 5 N. The robot head module showed almost the same force responses at the two points.

  12. Multi-drug resistant Acinetobacter infections in critically injured Canadian forces soldiers

    Directory of Open Access Journals (Sweden)

    Brisebois Ronald

    2007-08-01

    Full Text Available Abstract Background Military members, injured in Afghanistan or Iraq, have returned home with multi-drug resistant Acinetobacter baumannii infections. The source of these infections is unknown. Methods Retrospective study of all Canadian soldiers who were injured in Afghanistan and who required mechanical ventilation from January 1 2006 to September 1 2006. Patients who developed A. baumannii ventilator associated pneumonia (VAP were identified. All A. baumannii isolates were retrieved for study patients and compared with A. baumannii isolates from environmental sources from the Kandahar military hospital using pulsed-field gel electrophoresis (PFGE. Results During the study period, six Canadian Forces (CF soldiers were injured in Afghanistan, required mechanical ventilation and were repatriated to Canadian hospitals. Four of these patients developed A. baumannii VAP. A. baumannii was also isolated from one environmental source in Kandahar – a ventilator air intake filter. Patient isolates were genetically indistinguishable from each other and from the isolates cultured from the ventilator filter. These isolates were resistant to numerous classes of antimicrobials including the carbapenems. Conclusion These results suggest that the source of A. baumannii infection for these four patients was an environmental source in the military field hospital in Kandahar. A causal linkage, however, was not established with the ventilator. This study suggests that infection control efforts and further research should be focused on the military field hospital environment to prevent further multi-drug resistant A. baumannii infections in injured soldiers.

  13. Friction welding of a nickel free high nitrogen steel: influence of forge force on microstructure, mechanical properties and pitting corrosion resistance

    Directory of Open Access Journals (Sweden)

    Mrityunjoy Hazra

    2014-01-01

    Full Text Available In the present work, nickel free high nitrogen austenitic stainless steel specimens were joined by continuous drive friction welding process by varying the amount of forge (upsetting force and keeping other friction welding parameters such as friction force, burn-off, upset time and speed of rotation as constant at appropriate levels. The joint characterization studies include microstructural examination and evaluation of mechanical (micro-hardness, impact toughness and tensile and pitting corrosion behaviour. The integrity of the joint, as determined by the optical microscopy was very high and no crack and area of incomplete bonding were observed. Welds exhibited poor Charpy impact toughness than the parent material. Toughness for friction weld specimens decreased with increase in forge force. The tensile properties of all the welds were almost the same (irrespective of the value of the applied forge force and inferior to those of the parent material. The joints failed in the weld region for all the weld specimens. Weldments exhibited lower pitting corrosion resistance than the parent material and the corrosion resistance of the weld specimens was found to decrease with increase in forge force.

  14. Differences in supraspinal and spinal excitability during various force outputs of the biceps brachii in chronic- and non-resistance trained individuals.

    Directory of Open Access Journals (Sweden)

    Gregory E P Pearcey

    Full Text Available Motor evoked potentials (MEP and cervicomedullary evoked potentials (CMEP may help determine the corticospinal adaptations underlying chronic resistance training-induced increases in voluntary force production. The purpose of the study was to determine the effect of chronic resistance training on corticospinal excitability (CE of the biceps brachii during elbow flexion contractions at various intensities and the CNS site (i.e. supraspinal or spinal predominantly responsible for any training-induced differences in CE. Fifteen male subjects were divided into two groups: 1 chronic resistance-trained (RT, (n = 8 and 2 non-RT, (n = 7. Each group performed four sets of ∼5 s elbow flexion contractions of the dominant arm at 10 target forces (from 10%-100% MVC. During each contraction, subjects received 1 transcranial magnetic stimulation, 2 transmastoid electrical stimulation and 3 brachial plexus electrical stimulation, to determine MEP, CMEP and compound muscle action potential (Mmax amplitudes, respectively, of the biceps brachii. All MEP and CMEP amplitudes were normalized to Mmax. MEP amplitudes were similar in both groups up to 50% MVC, however, beyond 50% MVC, MEP amplitudes were lower in the chronic RT group (p<0.05. CMEP amplitudes recorded from 10-100% MVC were similar for both groups. The ratio of MEP amplitude/absolute force and CMEP amplitude/absolute force were reduced (p<0.012 at all contraction intensities from 10-100% MVC in the chronic-RT compared to the non-RT group. In conclusion, chronic resistance training alters supraspinal and spinal excitability. However, adaptations in the spinal cord (i.e. motoneurone seem to have a greater influence on the altered CE.

  15. Comparison of forced expiratory spirometric flow changes following ...

    African Journals Online (AJOL)

    Group B received intrathecal anaesthesia 15 mgs of bupivacaine with 0.5 ml of normal saline and Group BF received 15 mgs of bupivacaine with 0.5 ml of fentanyl (25 μg) intrathecally. The patients were instructed about the performance of the spirometry on the previous evening of the surgery. Forced vital capacity, forced ...

  16. 46 CFR 169.642 - Vital systems.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Vital systems. 169.642 Section 169.642 Shipping COAST... Electrical Piping Systems § 169.642 Vital systems. For the purpose of this part, the following are considered vital systems— (a) A marine engineering system identified by the OCMI as being crucial to the survival...

  17. Down force calibration stand test report

    International Nuclear Information System (INIS)

    BOGER, R.M.

    1999-01-01

    The Down Force Calibration Stand was developed to provide an improved means of calibrating equipment used to apply, display and record Core Sample Truck (CST) down force. Originally, four springs were used in parallel to provide a system of resistance that allowed increasing force over increasing displacement. This spring system, though originally deemed adequate, was eventually found to be unstable laterally. For this reason, it was determined that a new method for resisting down force was needed

  18. Incidence of post-operative pain following single visit endodontics in vital and non-vital teeth: An in vivo study

    Science.gov (United States)

    Bhagwat, Sumita; Mehta, Deepil

    2013-01-01

    This clinical study was conducted to compare the post-operative pain following single visit endodontics in vital and non-vital teeth, with and without periapical radiolucency. A total of 60 adult patients requiring root canal therapy in anterior and premolar teeth were selected for this study. Single sitting root canal treatment was carried out and the subjects were recalled after 2 weeks and instructed to fill out a series of self-report questionnaires for responses about pain in the interim after 1 day, 2 day, 3 day, 1 week and 2 weeks. In vital teeth (Group I) 60% of the treated cases had pain, of which 36% had mild pain (non-significant) and 24% had moderate pain (significant). In non-vital teeth without periapical radiolucency (Group II) 64% of cases had pain, of which 48% had mild pain (non-significant) and 16% had moderate pain (significant). In non-vital teeth with periapical radiolucency (Group III) 32% of the cases had pain of which 24% had mild pain (non-significant) and 8% had moderate pain (significant). None of the teeth in any of the groups had severe pain. There was no statistical difference between incidence of pain in vital and non-vital teeth without periapical radiolucency. Non-vital teeth with periapical radiolucency exhibited relatively less pain as compared with non-vital teeth without periapical radiolucency, but the pain continued in a significant percent of teeth even after 2 weeks. Pain incidence dropped significantly within a period of 1 day to 2 weeks in vital teeth and non-vital teeth without periapical radiolucency. There was a tendency for less incidence of significant pain after a single visit root canal treatment in these groups. Results obtained were comparable with those obtained by several investigators. PMID:24124293

  19. Effect of resistance training on muscle strength and rate of force development in healthy older adults: A systematic review and meta-analysis.

    Science.gov (United States)

    Guizelini, Pedrode Camargo; de Aguiar, Rafael Alves; Denadai, Benedito Sérgio; Caputo, Fabrizio; Greco, Camila Coelho

    2018-02-01

    Rapid force capacity, identified by rate of rise in contractile force at the onset of contraction, i.e., the rate of force development (RFD), has been considered an important neuromuscular parameter of physical fitness in elderly individuals. Randomized control studies conducted in adults have found that resistance training may elicit different outcomes in terms of RFD and muscle strength. Thus, the main purpose of this study was to review systematically the literature for studies regarding the influence of resistance training on muscle strength and RFD in elderly persons. A literature search was performed in major electronic databases from inception to March 2017. Studies including health individuals with a mean age≥60years, describing the effect of resistance training on RFD and muscle strength were found eligible. The outcomes were calculated as the difference in percentage change between control and experimental groups (% change) and data were presented as mean±95% confidence limits. Meta-analyses were performed using a random-effects model and, in addition, simple and multiple meta-regression analyses were used to identify effects of age, training type, sessions per week and training duration on % change in RFD and muscle strength. Thirteen training effects were collected from 10 studies included in the meta-analysis. The resistance training program had a moderate beneficial effect on both muscle strength (% change=18.40%, 95% CL 13.69-23.30, pchange=26.68, 95% CL 14.41-35.52, pchanges in muscle strength and RFD. It can be concluded that explosive training and heavy strength training are effective resistance training methods aiming to improve both muscle strength and RFD after short-to-medium training period. However, muscle strength and RFD seem to adapt differently to resistance training programs, suggesting caution for their interchangeable use in clinical assessments of the elderly. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. A novel copper complex induces ROS generation in doxorubicin resistant Ehrlich ascitis carcinoma cells and increases activity of antioxidant enzymes in vital organs in vivo

    International Nuclear Information System (INIS)

    Mookerjee, Ananda; Roy, Syamal; Choudhuri, Soumitra K; Basu, Jayati Mookerjee; Majumder, Surajit; Chatterjee, Shilpak; Panda, Gouri S; Dutta, Pranabananda; Pal, Smarajit; Mukherjee, Pratima; Efferth, Thomas

    2006-01-01

    In search of a suitable GSH-depleting agent, a novel copper complex viz., copper N-(2-hydroxyacetophenone) glycinate (CuNG) has been synthesized, which was initially found to be a potential resistance modifying agent and later found to be an immunomodulator in mice model in different doses. The objective of the present work was to decipher the effect of CuNG on reactive oxygen species (ROS) generation and antioxidant enzymes in normal and doxorubicin-resistant Ehrlich ascites carcinoma (EAC/Dox)-bearing Swiss albino mice. The effect of CuNG has been studied on ROS generation, multidrug resistance-associated protein1 (MRP1) expression and on activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx). CuNG increased ROS generation and reduced MRP1 expression in EAC/Dox cells while only temporarily depleted glutathione (GSH) within 2 h in heart, kidney, liver and lung of EAC/Dox bearing mice, which were restored within 24 h. The level of liver Cu was observed to be inversely proportional to the level of GSH. Moreover, CuNG modulated SOD, CAT and GPx in different organs and thereby reduced oxidative stress. Thus nontoxic dose of CuNG may be utilized to reduce MRP1 expression and thus sensitize EAC/Dox cells to standard chemotherapy. Moreover, CuNG modulated SOD, CAT and and GPx activities to reduce oxidative stress in some vital organs of EAC/Dox bearing mice. CuNG treatment also helped to recover liver and renal function in EAC/Dox bearing mice. Based on our studies, we conclude that CuNG may be a promising candidate to sensitize drug resistant cancers in the clinic

  1. Design and evaluation of a low thermal electromotive force guarded scanner for resistance measurements

    Science.gov (United States)

    Jarrett, Dean G.; Marshall, James A.; Marshall, Thomas A.; Dziuba, Ronald F.

    1999-06-01

    The design and testing of a low thermal electromotive force guarded scanner, developed to provide completely guarded switching when used with actively guarded resistance bridge networks, is described. The design provides a continuous guard circuit trace on the scanner circuit boards that surrounds the relay contacts and protects the measurement circuit from leakages to ground. Modification to the circuit boards and relays of the guarded scanner are explained. Several tests were developed to evaluate the guarding effectiveness, including isolating sections of the guard circuit to create a potential drop between the main and guard circuits. Calibration of standard resistors using the guarded scanner has shown relative differences less than 1×10-6, 30×10-6, and 150×10-6 for measurements made with and without the guarded scanner at nominal resistances of 1, 10, and 100 GΩ, respectively. The substitution method was used to significantly reduce the relative differences between channels to less than 0.5×10-6, 3×10-6, and 30×10-6 for nominal resistances of 1, 10, and 100 GΩ, respectively. Applications for the guarded scanner in automated direct current measurement systems are presented.

  2. New ways enhancing the vital activity of plants in order to increase crop yields and to suppress radionuclide accumulation

    International Nuclear Information System (INIS)

    Goncharova, N. V; Zebrakova, I. V.; Matsko, V. P.; Kislushko, P. M.

    1994-01-01

    After Chernobyl nuclear accident it has become very important to seek new ways of enhancing the vital activity of plants in order to increase crop yields and to suppress radionuclide accumulation. It is found that by optimizing the vital activity processes in plants, is possible to reduce radionuclide uptake. A great number of biologically active compounds have been tested, which increased the disease resistance of plants and simultaneously activated the physiological and biochemical processes that control the transport of micro- and macroelements (radionuclide included) and their 'soil-root-stem-leaf' redistribution. (author)

  3. Bone vitality in the cat's irradiated jaw

    International Nuclear Information System (INIS)

    Dambrain, R.; Dhem, A.; Gueulette, J.; Wambersie, A.

    1988-01-01

    The vitality of the mandible in cats was studied from two to 15 months after irradiation. Dose of 80 Gy in three days was delivered using three hairpin shape iridium-192 wires surrounding the mandibula. The osseous vitality was assessed from the percentages of lacunae inhabited by osteocytes (IL). The results are compared with those obtained by microradiography. At two months, a small reduction of vitality is already observed, it becomes progressively more important. At one year, vitality is recovered nearly fully in the ventral part of the mandibula, mainly at the level of the alveolar crest. Vitality remains reduced in the dorsal part. Microradiographic lesions appear more slowly; they are apparent at six months. (orig.) [de

  4. Técnica de oscilações forçadas na análise da resposta broncodilatadora em voluntários sadios e indivíduos portadores de asma brônquica com resposta positiva Using the forced oscillation technique to evaluate bronchodilator response in healthy volunteers and in asthma patients presenting a verified positive response

    Directory of Open Access Journals (Sweden)

    Juliana Veiga Cavalcanti

    2006-04-01

    Full Text Available OBJETIVO: Analisar, através da técnica de oscilações forçadas, pacientes asmáticos com resposta broncodilatadora positiva pelo laudo espirométrico e comparar esses resultados com os obtidos em indivíduos sadios. MÉTODOS: Foram analisados 53 indivíduos não tabagistas, sendo 24 sadios sem história de doença pulmonar e 29 asmáticos com resposta broncodilatadora positiva segundo o laudo espirométrico. Todos foram submetidos à técnica de oscilações forçadas e a espirometria antes e após vinte minutos da administração de salbutamol spray (300 g. Os parâmetros derivados da técnica de oscilações forçadas foram: resistência total, reatância total, resistência extrapolada para o eixo y, coeficiente angular da reta de resistência e complacência dinâmica. Na espirometria, os parâmetros utilizados foram o volume expiratório forçado no primeiro segundo e a capacidade vital forçada. RESULTADOS: No grupo controle, a utilização do broncodilatador produziu alteração significativa na resistência extrapolada para o eixo y (p OBJECTIVE: To use the forced oscillation technique to evaluate asthma patients presenting positive bronchodilator responses (confirmed through spirometry and compare the results with those obtained in healthy individuals. METHODS: The study sample consisted of 53 non-smoking volunteers: 24 healthy subjects with no history of pulmonary disease and 29 asthmatics presenting positive bronchodilator response, as determined through analysis of spirometry findings. All of the subjects were submitted to forced oscillation technique and spirometry immediately before and 20 minutes after the administration of salbutamol spray (300 g. The parameters derived from the forced oscillation technique were total respiratory resistance, total respiratory reactance, resistance extrapolated to the y axis, the slope of resistance, and dynamic compliance. The parameters measured in the spirometry evaluation tests were forced

  5. Handbook of force transducers

    CERN Document Server

    Stefanescu, Dan Mihai

    2011-01-01

    Part I introduces the basic ""Principles and Methods of Force Measurement"" acording to a classification into a dozen of force transducers types: resistive, inductive, capacitive, piezoelectric, electromagnetic, electrodynamic, magnetoelastic, galvanomagnetic (Hall-effect), vibrating wires, (micro)resonators, acoustic and gyroscopic. Two special chapters refer to force balance techniques and to combined methods in force measurement. Part II discusses the ""(Strain Gauge) Force Transducers Components"", evolving from the classical force transducer to the digital / intelligent one, with the inco

  6. Analysis of cardiovascular system responses to forced vital capacity in COPD Análise das respostas do sistema cardiovascular ao teste de capacidade vital forçada na DPOC

    Directory of Open Access Journals (Sweden)

    Felipe A. R. Mendes

    2011-04-01

    Full Text Available BACKGROUND: The forced vital capacity (FVC test is routinely performed to evaluate pulmonary function in patients with chronic obstructive pulmonary disease (COPD. However, the influence of the FVC maneuver on the cardiovascular system of patients with COPD is poorly understood. OBJECTIVES: To analyze the behavior of heart rate (HR, blood pressure (BP and heart rate variability (HRV during the FVC test in COPD patients. METHODS: Nineteen men with COPD (72±7 years, GOLD stage I=3, II=5, III=7 and IV=4 patients performed the FVC test while having their HR monitored. HRV was assessed in time (rMSSD and frequency domains (LF, HF and LF/HF at rest, before and after the best FVC maneuver. BP was measured at rest, immediately before and at the end of the test, as well as 10 minutes after the end of the test. RESULTS: At the beginning of the FVC maneuver, HR decreased (pCONTEXTUALIZAÇÃO: O teste de capacidade vital forçada (CVF é rotineiramente realizado na avaliação da função pulmonar de pacientes com doença pulmonar obstrutiva crônica (DPOC. Entretanto, permanece pouco compreendida a influência do teste de CVF sobre o sistema cardiovascular de pacientes com DPOC. OBJETIVOS: Analisar o comportamento da frequência cardíaca (FC, pressão arterial (PA e variabilidade da frequência cardíaca (VFC no teste de CVF na DPOC. MÉTODOS: Dezenove homens com DPOC (72 ± 7 anos, no estágio de gravidade GOLD I=3, II=5, III=7 e IV=4 pacientes realizaram a manobra de CVF e tiveram sua FC monitorada durante todo o exame, e a VFC analisada nos domínios do tempo (rMSSD e da frequência (BF, AF e BF/AF durante o repouso, antes e após a melhor manobra de CVF. A PA foi analisada no repouso, imediatamente ao final da manobra de CVF e 10 minutos após o término de todos os testes. RESULTADOS: Ao início da manobra de CVF, a FC reduziu (p<0,001 e, em seguida, aumentou progressivamente até o final do teste (p<0,001. Após término da manobra, a FC continuou

  7. Methods of sperm vitality assessment.

    Science.gov (United States)

    Moskovtsev, Sergey I; Librach, Clifford L

    2013-01-01

    Sperm vitality is a reflection of the proportion of live, membrane-intact spermatozoa determined by either dye exclusion or osmoregulatory capacity under hypo-osmotic conditions. In this chapter we address the two most common methods of sperm vitality assessment: eosin-nigrosin staining and the hypo-osmotic swelling test, both utilized in clinical Andrology laboratories.

  8. Flow resistance in rod assemblies

    International Nuclear Information System (INIS)

    Korsun, A.S.; Sokolova, M.S.

    2000-01-01

    The general form of relation between the resistance force and the velocity vector, resistance tensor structure and possible types of anisotropy in the flow thorough such structures as rod or tube assemblies are under discussion. Some questions of experimental determination of volumetric resistance force tensor are also under consideration. (author)

  9. Developing New Mexico Health Care Policy: An application of the Vital Issues Process

    Energy Technology Data Exchange (ETDEWEB)

    Engi, D. [Sandia National Labs., Albuquerque, NM (United States); Icerman, L. [Icerman & Associates, Santa Fe, NM (United States)

    1995-06-01

    The Vital Issues Process, developed by the Sandia National Laboratories Strategic Technologies Department, was utilized by the Health Care Task Force Advisory Group to apply structure to their policy deliberations. By convening three expert panels, an overarching goal for the New Mexico health care system, seven desired outcomes, nine policy options, and 17 action items were developed for the New Mexico health care system. Three broadly stated evaluation criteria were articulated and used to produce relative rankings of the desired outcomes and policy options for preventive care and information systems. Reports summarizing the policy deliberations were submitted for consideration by the Health Care Task Force, a Joint Interim Committee of the New Mexico Legislature, charged with facilitating the development and implementation of a comprehensive health care delivery system for New Mexico. The Task Force reported its findings and recommendations to the Second Session of the 41st New Mexico State Legislature in January 1994.

  10. The resistible force

    International Nuclear Information System (INIS)

    Baeschlin, D.L.

    1980-01-01

    Many people of today have an oppositional attitude towards the continual loss of sense of existence which manifests itself in 'the great refusal'. They also behave in an anti-authoritarian manner towards their first father Marx. They realize that it is ourselves who have to search and find. The protest groups of the most different origin have come into being as 'the sand in the wheels' of a seemingly irresistable force. They have formed themselves beyond the 'Left' and the 'Right'. Nuclear energy is the instrument which acts as a gear for their opposition, which establishes it and which provides the basis for their self-concept. It is the symbol where the conflict between living standard and living quality breaks open. In essential, however, the protest is growing towards supporting an effective administration of all goods of our world. (orig./HP) [de

  11. Identification of critical areas of carotid stent navigation by measurement of resistive forces in vitro, using silicone phantoms

    International Nuclear Information System (INIS)

    Sengupta, A.; Kesavadas, T.; Baier, R.E.; Hoffmann, K.R.; Schafer, S.

    2007-01-01

    Manipulation of surgical tools in neuro-endovascular surgery presents problems that are unique to this procedure. Navigating tools through arterial complexities without appropriate visual or force feedback information often causes tool snagging, plaque dislocations and formation of thrombosis from the damage of the arterial wall by the tools. Identifying the critical areas in the vasculature during navigation of endovascular tools, will not only ensure safer surgical planning but also reduce risks of vessel damage. In the present research, resistive forces of stent navigation were measured in-vitro using silicone phantoms and clinically relevant surgical devices. The patterns of variation of the forces along the path of the stent movement were analyzed and mapped along the path of stent movement using a color code. It was observed that the forces changed along the length of the vessel, independent of the insertion length but based on the curvature of the vessel and the contact area of the device in the vessel lumen. (orig.)

  12. Outwitting the series resistance in scanning spreading resistance microscopy

    International Nuclear Information System (INIS)

    Schulze, A.; Cao, R.; Eyben, P.; Hantschel, T.; Vandervorst, W.

    2016-01-01

    The performance of nanoelectronics devices critically depends on the distribution of active dopants inside these structures. For this reason, dopant profiling has been defined as one of the major metrology challenges by the international technology roadmap of semiconductors. Scanning spreading resistance microscopy (SSRM) has evolved as one of the most viable approaches over the last decade due to its excellent spatial resolution, sensitivity and quantification accuracy. However, in case of advanced device architectures like fins and nanowires a proper measurement of the spreading resistance is often hampered by the increasing impact of parasitic series resistances (e.g. bulk series resistance) arising from the confined nature of the aforementioned structures. In order to overcome this limitation we report in this paper the development and implementation of a novel SSRM mode (fast Fourier transform-SSRM: FFT-SSRM) which essentially decouples the spreading resistance from parasitic series resistance components. We show that this can be achieved by a force modulation (leading to a modulated spreading resistance signal) in combination with a lock-in deconvolution concept. In this paper we first introduce the principle of operation of the technique. We discuss in detail the underlying physical mechanisms as well as the technical implementation on a state-of-the-art atomic force microscope (AFM). We demonstrate the performance of FFT-SSRM and its ability to remove substantial series resistance components in practice. Eventually, the possibility of decoupling the spreading resistance from the intrinsic probe resistance will be demonstrated and discussed. - Highlights: • A novel electrical AFM mode for carrier profiling in confined volumes is presented. • Thereby the force and hence the contact area between AFM probe and sample is modulated. • Information on the spreading resistance is derived using a lock-in approach. • Bulk series resistance components are

  13. Effect of contraction mode of slow-speed resistance training on the maximum rate of force development in the human quadriceps

    DEFF Research Database (Denmark)

    Blazevich, Anthony J; Horne, Sara; Cannavan, Dale

    2008-01-01

    This study examined the effects of slow-speed resistance training involving concentric (CON, n = 10) versus eccentric (ECC, n = 11) single-joint muscle contractions on contractile rate of force development (RFD) and neuromuscular activity (EMG), and its maintenance through detraining. Isokinetic...

  14. Vitality: Carnal, Seraphic Bodies

    Directory of Open Access Journals (Sweden)

    Brian Treanor

    2017-09-01

    Full Text Available This paper reflects on experiences of what i call vitality. Such experiences are neither idiosyncratic (they overlap major themes in Chinese philosophy, among other disciplines nor mere romanticism (contemporary psychology lends credence to these accounts. Moreover, while some figures in continental philosophy do address the body—as perceiving, as sexed, as political—there has been almost no attention given to the active body of vitality. Drawing from the work of Michel Serres, this paper will uncover some of the significant features of such bodily experiences.

  15. Surface potential measurement on contact resistance of amorphous-InGaZnO thin film transistors by Kelvin probe force microscopy

    Science.gov (United States)

    Han, Zhiheng; Xu, Guangwei; Wang, Wei; Lu, Congyan; Lu, Nianduan; Ji, Zhuoyu; Li, Ling; Liu, Ming

    2016-07-01

    Contact resistance plays an important role in amorphous InGaZnO (a-IGZO) thin film transistors (TFTs). In this paper, the surface potential distributions along the channel have been measured by using Kelvin probe force microscopy (KPFM) on operating a-IGZO TFTs, and sharp potential drops at the edges of source and drain were observed. The source and drain contact resistances can be extracted by dividing sharp potential drops with the corresponding drain to source current. It is found that the contact resistances could not be neglected compared with the whole channel resistances in the a-IGZO TFT, and the contact resistances decrease remarkably with increasing gate biased voltage. Our results suggest that the contact resistances can be controlled by tuning the gate biased voltage. Moreover, a transition from gradual channel approximation to space charge region was observed through the surface potential map directly when TFT operating from linear regime to saturation regime.

  16. Sharing Vital Signs between mobile phone applications.

    Science.gov (United States)

    Karlen, Walter; Dumont, Guy A; Scheffer, Cornie

    2014-01-01

    We propose a communication library, ShareVitalSigns, for the standardized exchange of vital sign information between health applications running on mobile platforms. The library allows an application to request one or multiple vital signs from independent measurement applications on the Android OS. Compatible measurement applications are automatically detected and can be launched from within the requesting application, simplifying the work flow for the user and reducing typing errors. Data is shared between applications using intents, a passive data structure available on Android OS. The library is accompanied by a test application which serves as a demonstrator. The secure exchange of vital sign information using a standardized library like ShareVitalSigns will facilitate the integration of measurement applications into diagnostic and other high level health monitoring applications and reduce errors due to manual entry of information.

  17. Vital exhaustion and risk for cancer

    DEFF Research Database (Denmark)

    Bergelt, Corinna; Christensen, Jane Hvarregaard; Prescott, Eva

    2005-01-01

    Vital exhaustion, defined as feelings of depression and fatigue, has previously been investigated mainly as a risk factor for cardiovascular disease. The authors investigated the association between depressive feelings and fatigue as covered by the concept of vital exhaustion and the risk...

  18. TESTING OF PULP VITALITY BY PULSOXIMETRY

    Directory of Open Access Journals (Sweden)

    Gabriela CIOBANU

    2012-06-01

    Full Text Available The methods applied for diagnosing the health condition of the pulp tissue are numerous, however, nowadays, an increasingly higher number of conventional tests are replaced by some objective, non-invasive, painless and reliable tests. Among them, pulse oximetry is a method for the investigation of pulp vitality based on oxygen saturation (SaO2 of the hemoglobin from the blood present in the pulp vascular bed, as a means of differentiating among the vital and the non-vital teeth. In the present study, registrations were made on a group of 120 frontal maxillary teeth, in patients with ages between 20 and 40 years, on using a digital sensor modified by the pulse oximeter with which the pulse and the values of oxygen saturation were measured at the level of both teeth and right hand finger. The mean SaO2 value in the pulp blood of the vital teeth was of 83.30% for the central incisor, of 78.51% for the lateral one and of 84.56%, respectively, for the canine; the value recorded at finger level was of 97%. In the non-vital teeth, the SaO2 value measured on the pulse oximeter was of 0%. Pulse registration showed mean values of 70.56 beatings/min at tooth level and of 70.88 beatings/min, respectively, at finger level. The results of the present study may confirm that pulse oximetry represents a simple, non-traumatic, efficient and objective method for testing the vitality condition of the dental pulp.

  19. Vital exhaustion and risk for cancer

    DEFF Research Database (Denmark)

    Bergelt, Corinna; Christensen, Jane Hvarregaard; Prescott, Eva

    2005-01-01

    Vital exhaustion, defined as feelings of depression and fatigue, has previously been investigated mainly as a risk factor for cardiovascular disease. The authors investigated the association between depressive feelings and fatigue as covered by the concept of vital exhaustion and the risk...... for cancer....

  20. Vital soil; function, value and properties

    NARCIS (Netherlands)

    Doelman, P.; Eijsackers, H.J.P.

    2004-01-01

    Healthy soil, with active soil life, deters long-term soil degradation and ensures that geo-physical processes are undisturbed. Is the vitality of soil under threat due to human civilization? Or is it due to contamination, intensification, and deforestation? Vital Soil aims to look at the effects

  1. Formation of closely packed Cu nanoparticle films by capillary immersion force for preparing low-resistivity Cu films at low temperature

    Energy Technology Data Exchange (ETDEWEB)

    Yokoyama, Shun, E-mail: shun.yokoyama.c2@tohoku.ac.jp; Motomiya, Kenichi; Takahashi, Hideyuki; Tohji, Kazuyuki [Tohoku University, Graduate School of Environmental Studies (Japan)

    2016-11-15

    Films made of closely packed Cu nanoparticles (NPs) were obtained by drop casting Cu NP inks. The capillary immersion force exerted during the drying of the inks caused the Cu NPs to attract each other, resulting in closely packed Cu NP films. The apparent density of the films was found to depend on the type of solvent in the ink because the capillary immersion force is affected by the solvent surface tension and dispersibility of Cu NPs in the solvent. The closely packed particulate structure facilitated the sintering of Cu NPs even at low temperature, leading to low-resistivity Cu films. The sintering was also enhanced with a decrease in the size of NPs used. We demonstrated that a closely packed particulate structure using Cu NPs with a mean diameter 61.7 nm showed lower resistivity (7.6 μΩ cm) than a traditionally made Cu NP film (162 μΩ cm) after heat treatment.

  2. Femoral head vitality after intracapsular hip fracture

    International Nuclear Information System (INIS)

    Stroemqvist, B.

    1983-01-01

    Femoral head vitality before, during and at various intervals from the operation was determined by tetracycline labeling and/or 99 sp (m)Tc-MDP scintimetry. In a three-year follow-up, healing prognosis could be determined by scintimetry 3 weeks from operation; deficient femoral head vitality predicting healing complications and retained vitality predicting uncomplicated healing. A comparison between pre- and postoperative scintimetry indicated that further impairment of the femoral head vitality could be caused by the operative procedure, and as tetracycline labeling prior to and after fracture reduction in 370 fractures proved equivalent, it was concluded that the procedure of osteosynthesis probably was responsible for capsular vessel injury, using a four-flanged nail. The four-flanged nail was compared with a low-traumatic method of osteosynthesis, two hook-pins, in a prospective randomized 14 month study, and the postoperative femoral head vitality was significantly better in the hook-pin group. This was also clearly demonstrated in a one-year follow-up for the fractures included in the study. Parallel to these investigations, the reliability of the methods of vitality determination was found satisfactory in methodologic studies. For clinical purpose, primary atraumatic osteosynthesis, postoperative prognostic scintimetry and early secondary arthroplasty when indicated, was concluded to be the appropriate approach to femoral neck fracture treatment. (Author)

  3. The effect of inter-implant distance on retention and resistance to dislodging forces for mandibular implant-tissue-supported overdentures.

    Directory of Open Access Journals (Sweden)

    Farhad Tabatabaian

    2014-10-01

    Full Text Available The effect of inter-implant distance on retention and resistance of implant-tissue-supported overdentures is lacking in the literature. An in vitro study was performed to evaluate this effect for mandibular implant-tissue-supported overdentures retained by two ball attachments.An acrylic cast of an edentulous mandible was fabricated. Three pairs of implants were symmetrically placed at both sides of the midline. The inter-implant distance was 10, 25, and 35 millimeters in positions A, B and C, respectively. A framework simulating the overdenture was fabricated on the cast. Six attachment housings were placed within the overdenture. For each sample, two ball abutments were screwed onto the implant pairs and two pink nylon inserts were seated in their respective attachment housings. The samples were tested in three groups of 15 (A, B, and C. The testing machine applied tensile dislodging forces and peak loads were measured in three directions: vertical, oblique, and anterior-posterior. A one-way ANOVA followed by Tukey's HSD was used to determine groups that were significantly different. Tests were carried out at 0.05 level of significance.Peak loads for the anterior-posteriorly directed dislodging forces were significantly the highest for group C (P0.05.Inter-implant distance did not affect the vertical retention and oblique resistance of mandibular implant-tissue-supported overdentures; however, it affected anterior-posterior resistance.

  4. INFLUENCE OF APPLYING ADDITIONAL FORCING FANS FOR THE AIR DISTRIBUTION IN VENTILATION NETWORK

    Directory of Open Access Journals (Sweden)

    Nikodem SZLĄZAK

    2016-07-01

    Full Text Available Mining progress in underground mines cause the ongoing movement of working areas. Consequently, it becomes neces-sary to adapt the ventilation network of a mine to direct airflow into newly-opened districts. For economic reasons, opening new fields is often achieved via underground workings. Length of primary intake and return routes increases and also increases the total resistance of a complex ventilation network. The development of a subsurface structure can make it necessary to change the air distribution in a ventilation network. Increasing airflow into newly-opened districts is necessary. In mines where extraction does not entail gas-related hazards, there is possibility of implementing a push-pull ventilation system in order to supplement airflows to newly developed mining fields. This is achieved by installing sub-surface fan stations with forcing fans at the bottom of downcast shaft. In push-pull systems with multiple main fans, it is vital to select forcing fans with characteristic curves matching those of the existing exhaust fans to prevent undesirable mutual interaction. In complex ventilation networks it is necessary to calculate distribution of airflow (especially in net-works with a large number of installed fans. In the article the influence of applying additional forcing fans for the air distribution in ventilation network for underground mine were considered. There are also analysed the extent of over-pressure caused by the additional forcing fan in branches of the ventilation network (the operating range of additional forcing fan. Possibilities of increasing airflow rate in working areas were conducted.

  5. The quality of colostrum and vitality of calves, born from cows with different reaction to stress experiences

    Directory of Open Access Journals (Sweden)

    O. M. Chernenko

    2017-04-01

    Full Text Available The article presents the results of studying cortisol concentration and creatine phosphokinase activity in the blood serum of 40 half-sib Ukrainian black and white dairy cows an hour after planned blood extraction, which was a stress experience. We divided the cows into three groups according to the distribution of cortisol concentration in the animals: I – high, II – average and III – low stress resistance. During the research, the cows from these groups were in their fourth month of lactation after their first calving. They were kept untethered in their summer quarters, natural pastures. The aim of the research was to identify the differences in the quality of colostrum, the vitality of the calves up to the age of 6 months, the vitality of the mother-cows, and also the influence of their different adaptation potentials in cases of abortion and stillborn calves among the cows from different groups. At the dairy complex where the research was conducted, the quality of the cows’ colostrum is not monitored. This is typical for most dairy plants of Ukraine. We found that the classes of A and M immunoglobulins did not depend upon which particular groups the animals belonged to, whereas the content of immunoglobulins of class G is 6.7 g/l higher, and the content of total protein is 8.9 g/l higher in the yield of colostrum of the cows from group 1. The influence of cows’ different levels of resistance to stress experiences on their incidence of abortions and stillborn calves was not determined. Gastroenteritis occurred among calves of cows from group 3 three times more often than with those of group 1. Vitality of calves from cows of groups 1 and 2 was significantly higher. Therefore, technological stress experiences of mother-cows have a negative effect upon the quality of colostrum and upon the vitality of calves. This factor ought to be taken into consideration in the exploitation of animals, especially during pregnancy in order to

  6. Constructive consequences of leaders' forcing influence styles

    NARCIS (Netherlands)

    Emans, B.J.M.; Munduate, L; Klaver, E; Van de Vliert, E.

    In contrast to non-forcing influence styles used by leaders, their forcing influence styles are commonly found to be ineffective, evoking sheer resistance, rather than compliance. As a corollary of conglomerate conflict behavior theory, we state that forcing, if combined with non-forcing, may

  7. Organic condensation: A vital link connecting aerosol formation to climate forcing (Invited)

    Science.gov (United States)

    Riipinen, I.; Pierce, J. R.; Yli-Juuti, T.; Nieminen, T.; Häkkinen, S.; Ehn, M.; Junninen, H.; Lehtipalo, K.; Petdjd, T. T.; Slowik, J. G.; Chang, R. Y.; Shantz, N. C.; Abbatt, J.; Leaitch, W. R.; Kerminen, V.; Worsnop, D. R.; Pandis, S. N.; Donahue, N. M.; Kulmala, M. T.

    2010-12-01

    Aerosol-cloud interactions represent the largest uncertainty in calculations of Earth’s radiative forcing. Number concentrations of atmospheric aerosol particles are in the core of this uncertainty, as they govern the numbers of cloud condensation nuclei (CCN) and influence the albedo and lifetime of clouds. Aerosols also impair air quality through their adverse effects on atmospheric visibility and human health. The ultrafine fraction ( 100 nm) and enhance the loss of ultrafine particles. Primary organic aerosol (POA) contributes to the large end of the aerosol size distribution, enhancing the scavenging of the ultrafine particles.

  8. Changes in muscle cross-sectional area, muscle force, and jump performance during 6 weeks of progressive whole-body vibration combined with progressive, high intensity resistance training

    Science.gov (United States)

    Rosenberger, A.; Beijer, Å.; Johannes, B.; Schoenau, E.; Mester, J.; Rittweger, J.; Zange, J.

    2017-01-01

    Objectives: We hypothesized that progressive whole-body vibration (WBV) superimposed to progressive high intensity resistance training has greater effects on muscle cross-sectional area (CSA), muscle force of leg muscles, and jump performance than progressive high intensity resistance training alone. Methods: Two groups of healthy male subjects performed either 6 weeks of Resistive Vibration Exercise (RVE, squats and heel raises with WBV, n=13) or Resistive Exercise (RE, squats and heel raises without WBV, n=13). Squats under RVE required indispensable weight loading on the forefoot to damp harmful vibrations to the head. Time, intervention, and interaction effects were analyzed. Results: After 6 weeks of training, knee extensor CSA, isometric knee extension force, and counter movement jump height increased equally in both groups (time effect, P<0.001, P≤0.02, and P≤0.03, respectively), whereas only in RVE ankle plantar flexor CSA and isometric ankle plantar flexion force reached significance or a tendency, respectively, (time effect, P=0.015 and P=0.069, respectively; intervention effect also for the latter, P=0.006). Drop jump contact time did significantly more improve in RVE (interaction effect, P=0.042). Conclusions: RVE showed better training effects than RE only in plantar flexor muscles. RVE seems to be suitable in professional sports with a special focus on calf muscles. PMID:28574410

  9. Validation of the Subjective Vitality Scale and study of the vitality of elderly people according to their physical activity

    Directory of Open Access Journals (Sweden)

    Nuno Couto

    2017-08-01

    Full Text Available The main aim of the study was to validate the Portuguese version of the Subjective Vitality Scale - SVS for the Portuguese elderly population through of confirmatory factorial analysis. The existence of differences in the perception of subjective vitality among sufficiently active and insufficiently active older adults was also analyzed. A total of 309 Portuguese elderly (242 females, 67 males aged 60-90 years (M = 68.59, SD = 6.60 participated in this study. Of the total sample, 256 are sufficiently active, while 53 are insufficiently active. The results show that the model was adjusted to data in a satisfactory way (χ² = 28.95; df = 9; CFI = .97; TLI = .94; SRMR = .04; RMSEA = .08; RMSEA 90% CI = .05 - .12, and show a concurrent validity with the Portuguese version of the Satisfaction with Life Scale. The data obtained allow us concluding that the Portuguese version of the Subjective Vitality Scale can be used as a measure of subjective vitality in the Portuguese elderly population. It was also verified that the subjective perception of vitality is greater among individuals sufficiently active compared with their peers that do not reach the amount of practice of recommended physical activity.

  10. Resisting force characteristics of a mechanical snubber and its restraint effect on beam deformation

    International Nuclear Information System (INIS)

    Ohmata, Kenichiro

    1987-01-01

    A mechanical snubber is used to restrain piping systems in nuclear power plants during an earthquake. It has nonlinearities in both load (or exciting amplitude) and frequency response, so it will be very difficult to analyze the resisting force characteristics of the mechanical snubber theoretically. In this report, the equation of motion of the mechanical snubber is derived and digital simulations of snubber dynamic characteristics over a frequency range are carried out using the Continuous System Simulation Language (CSSL). Also, the restraint effect of the mechanical snubber applied to a simple beam is discussed both numerically and experimentally. The beam is replaced by a lumped mass system and CSSL is used to perform the digital simulations. (author)

  11. Wide range local resistance imaging on fragile materials by conducting probe atomic force microscopy in intermittent contact mode

    Energy Technology Data Exchange (ETDEWEB)

    Vecchiola, Aymeric [Laboratoire de Génie électrique et électronique de Paris (GeePs), UMR 8507 CNRS-CentraleSupélec, Paris-Sud and UPMC Universities, 11 rue Joliot-Curie, Plateau de Moulon, 91192 Gif-sur-Yvette (France); Concept Scientific Instruments, ZA de Courtaboeuf, 2 rue de la Terre de Feu, 91940 Les Ulis (France); Unité Mixte de Physique CNRS-Thales UMR 137, 1 avenue Augustin Fresnel, 91767 Palaiseau (France); Chrétien, Pascal; Schneegans, Olivier; Mencaraglia, Denis; Houzé, Frédéric, E-mail: frederic.houze@geeps.centralesupelec.fr [Laboratoire de Génie électrique et électronique de Paris (GeePs), UMR 8507 CNRS-CentraleSupélec, Paris-Sud and UPMC Universities, 11 rue Joliot-Curie, Plateau de Moulon, 91192 Gif-sur-Yvette (France); Delprat, Sophie [Unité Mixte de Physique CNRS-Thales UMR 137, 1 avenue Augustin Fresnel, 91767 Palaiseau (France); UPMC, Université Paris 06, 4 place Jussieu, 75005 Paris (France); Bouzehouane, Karim; Seneor, Pierre; Mattana, Richard [Unité Mixte de Physique CNRS-Thales UMR 137, 1 avenue Augustin Fresnel, 91767 Palaiseau (France); Tatay, Sergio [Molecular Science Institute, University of Valencia, 46980 Paterna (Spain); Geffroy, Bernard [Lab. Physique des Interfaces et Couches minces (PICM), UMR 7647 CNRS-École polytechnique, 91128 Palaiseau (France); Lab. d' Innovation en Chimie des Surfaces et Nanosciences (LICSEN), NIMBE UMR 3685 CNRS-CEA Saclay, 91191 Gif-sur-Yvette (France); and others

    2016-06-13

    An imaging technique associating a slowly intermittent contact mode of atomic force microscopy (AFM) with a home-made multi-purpose resistance sensing device is presented. It aims at extending the widespread resistance measurements classically operated in contact mode AFM to broaden their application fields to soft materials (molecular electronics, biology) and fragile or weakly anchored nano-objects, for which nanoscale electrical characterization is highly demanded and often proves to be a challenging task in contact mode. Compared with the state of the art concerning less aggressive solutions for AFM electrical imaging, our technique brings a significantly wider range of resistance measurement (over 10 decades) without any manual switching, which is a major advantage for the characterization of materials with large on-sample resistance variations. After describing the basics of the set-up, we report on preliminary investigations focused on academic samples of self-assembled monolayers with various thicknesses as a demonstrator of the imaging capabilities of our instrument, from qualitative and semi-quantitative viewpoints. Then two application examples are presented, regarding an organic photovoltaic thin film and an array of individual vertical carbon nanotubes. Both attest the relevance of the technique for the control and optimization of technological processes.

  12. Real time relationship between individual finger force and grip exertion on distal phalanges in linear force following tasks.

    Science.gov (United States)

    Luo, Shi-Jian; Shu, Ge; Gong, Yan

    2018-05-01

    Individual finger force (FF) in a grip task is a vital concern in rehabilitation engineering and precise control of manipulators because disorders in any of the fingers will affect the stability or accuracy of the grip force (GF). To understand the functions of each finger in a dynamic grip exertion task, a GF following experiment with four individual fingers without thumb was designed. This study obtained four individual FFs from the distal phalanges with a cylindrical handle in dynamic GF following tasks. Ten healthy male subjects with similar hand sizes participated in the four-finger linear GF following tasks at different submaximal voluntary contraction (SMVC) levels. The total GF, individual FF, finger force contribution, and following error were subsequently calculated and analyzed. The statistics indicated the following: 1) the accuracy and stability of GF at low %MVC were significantly higher than those at high SMVC; 2) at low SMVC, the ability of the fingers to increase the GF was better than the ability to reduce it, but it was contrary at high SMVC; 3) when the target wave (TW) was changing, all four fingers strongly participated in the force exertion, but the participation of the little finger decreased significantly when TW remained stable; 4) the index finger and ring finger had a complementary relationship and played a vital role in the adjustment and control of GF. The middle finger and little finger had a minor influence on the force control and adjustment. In conclusion, each of the fingers had different functions in a GF following task. These findings can be used in the assessment of finger injury rehabilitation and for algorithms of precise control. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. The Common Forces: Conservative or Nonconservative?

    Science.gov (United States)

    Keeports, David

    2006-01-01

    Of the forces commonly encountered when solving problems in Newtonian mechanics, introductory texts usually limit illustrations of the definitions of conservative and nonconservative forces to gravity, spring forces, kinetic friction and fluid resistance. However, at the expense of very little class time, the question of whether each of the common…

  14. Vital areas at nuclear power plants

    International Nuclear Information System (INIS)

    Cameron, D.F.

    1985-01-01

    Vital area analysis of nuclear power plants has been performed for the Nuclear Regulatory Commission by the Los Alamos National Laboratory from the late 1970's through the present. The Los Alamos Vital Area Study uses a fault-tree modeling technique to identify vital areas and equipment at nuclear power plants to determine their vulnerability. This technique has been applied to all operating plants and approximately one-half of those under construction in the US. All saboteur-induced loss-of-coolant accidents and transients and the systems needed to mitigate them are considered. As a result of this effort, security programs at nuclear power plants now include vulnerability studies that identify targets in a systematic manner, and thus unnecessary protection has been minimized. 1 ref., 8 figs., 1 tab

  15. Health, vital goals, and central human capabilities.

    Science.gov (United States)

    Venkatapuram, Sridhar

    2013-06-01

    I argue for a conception of health as a person's ability to achieve or exercise a cluster of basic human activities. These basic activities are in turn specified through free-standing ethical reasoning about what constitutes a minimal conception of a human life with equal human dignity in the modern world. I arrive at this conception of health by closely following and modifying Lennart Nordenfelt's theory of health which presents health as the ability to achieve vital goals. Despite its strengths I transform Nordenfelt's argument in order to overcome three significant drawbacks. Nordenfelt makes vital goals relative to each community or context and significantly reflective of personal preferences. By doing so, Nordenfelt's conception of health faces problems with both socially relative concepts of health and subjectively defined wellbeing. Moreover, Nordenfelt does not ever explicitly specify a set of vital goals. The theory of health advanced here replaces Nordenfelt's (seemingly) empty set of preferences and society-relative vital goals with a human species-wide conception of basic vital goals, or 'central human capabilities and functionings'. These central human capabilities come out of the capabilities approach (CA) now familiar in political philosophy and economics, and particularly reflect the work of Martha Nussbaum. As a result, the health of an individual should be understood as the ability to achieve a basic cluster of beings and doings-or having the overarching capability, a meta-capability, to achieve a set of central or vital inter-related capabilities and functionings. © 2012 John Wiley & Sons Ltd.

  16. A worksite vitality intervention for older hospital workers to improve vitality work engegement, productivity ans sick leave: results of a randomized controlled trial

    NARCIS (Netherlands)

    Strijk, J.E.; Proper, K.I.; Meschelen, W. van; Beek, A. van der

    2012-01-01

    Objectives A worksite vitality intervention aiming to improve lifestyle behaviors could be an effective tool to keep older workers vital, and thereby prolong their labor participation. Therefore, this study evaluates the effectiveness of such an intervention on vitality, work engagement,

  17. [The vitalism of Paul-Joseph Barthez (1734-1806)].

    Science.gov (United States)

    Han, Hee Jin

    2010-06-30

    In The Logic of Life (1970), Francois Jacob (1920- ), Nobel Prize laureate in Physiology or Medicine (1965), proclaimed the end of vitalism based on the concept of life. More than two decades before this capital sentence condemning vitalism was pronounced, Georges Canguilhem (1904-1995), a French philosopher of medicine, already acknowledged that eighteenth-century vitalism was scientifically retrograde and politically reactionary or counter-revolutionary insofar as it was rooted in the animism of Georg Ernst Stahl (1660-1734). The negative preconception of the term 'vitalism' came to be established as an orthodox view, since Claude Bernard (1813-1878) unfairly criticized contemporary vitalism in order to propagate his idea of experimental medicine. An eminent evolutionary biologist like Ernst Mayr (1904-2005) still defended similar views in This is Biology (1997), arguing that if vitalists were decisive and convincing in their rejection of the Cartesian model (negative heuristics), however they were equally indecisive and unconvincing in their own explanatory endeavors (positive heuristics). Historically speaking, vitalists came to the forefront for their outstanding criticism of Cartesian mechanism and physicochemical reductionism, while their innovative concepts and theories were underestimated and received much less attention. Is it true that vitalism was merely a pseudo-science, representing a kind of romanticism or mysticism in biomedical science? Did vitalists lack any positive heuristics in their biomedical research? Above all, what was actually the so.called 'vitalism'? This paper aims to reveal the positive heuristics of vitalism defined by Paul.Joseph Barthez (1734-1806) who was the founder of the vitalist school of Montpellier. To this end, his work and idea are introduced with regard to the vying doctrines in physiology and medicine. At the moment when he taught at the medical school of Montpellier, his colleagues advocated the mechanism of Rene

  18. Transfer factor, lung volumes, resistance and ventilation distribution in healthy adults.

    Science.gov (United States)

    Verbanck, Sylvia; Van Muylem, Alain; Schuermans, Daniel; Bautmans, Ivan; Thompson, Bruce; Vincken, Walter

    2016-01-01

    Monitoring of chronic lung disease requires reference values of lung function indices, including putative markers of small airway function, spanning a wide age range.We measured spirometry, transfer factor of the lung for carbon monoxide (TLCO), static lung volume, resistance and ventilation distribution in a healthy population, studying at least 20 subjects per sex and per decade between the ages of 20 and 80 years.With respect to the Global Lung Function Initiative reference data, our subjects had average z-scores for forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC of -0.12, 0.04 and -0.32, respectively. Reference equations were obtained which could account for a potential dependence of index variability on age and height. This was done for (but not limited to) indices that are pertinent to asthma and chronic obstructive pulmonary disease studies: forced expired volume in 6 s, forced expiratory flow, TLCO, specific airway conductance, residual volume (RV)/total lung capacity (TLC), and ventilation heterogeneity in acinar and conductive lung zones.Deterioration in acinar ventilation heterogeneity and lung clearance index with age were more marked beyond 60 years, and conductive ventilation heterogeneity showed the greatest increase in variability with age. The most clinically relevant deviation from published reference values concerned RV/TLC values, which were considerably smaller than American Thoracic Society/European Respiratory Society-endorsed reference values. Copyright ©ERS 2016.

  19. Effect of brief daily resistance training on rapid force development in painful neck and shoulder muscles

    DEFF Research Database (Denmark)

    Jay, Kenneth; Schraefel, Mc; Andersen, Christoffer H

    2013-01-01

    OBJECTIVE: To determine the effect of small daily amounts of progressive resistance training on rapid force development of painful neck/shoulder muscles. METHODS: 198 generally healthy adults with frequent neck/shoulder muscle pain (mean: age 43.1 years, computer use 93% of work time, 88% women......, duration of pain 186 day during the previous year) were randomly allocated to 2- or 12 min of daily progressive resistance training with elastic tubing or to a control group receiving weekly information on general health. A blinded assessor took measures at baseline and at 10-week follow-up; participants.......05) for both training groups. Maximal muscle strength increased only ~5-6% [mean and 95% confidence interval for 2- and 12-min groups to control, respectively: 2.5 Nm (0.05-0.73) and 2.2 Nm (0.01-0.70)]. No significant differences between the 2- and 12-min groups were evident. A weak but significant...

  20. CDC Vital Signs: Progress on Childhood Obesity

    Science.gov (United States)

    ... VitalSigns – Childhood Obesity [PSA – 0:60 seconds] VitalSigns – Obesidad en niños: [PODCAST – 1:15 minutes] Childhood Overweight ... Prevention and Control MedlinePlus – Obesity in Children MedlinePlus – Obesidad en niños Top of Page Get Email Updates ...

  1. Vital Signs-Secondhand Smoke

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the February 2015 CDC Vital Signs report. Secondhand smoke kills more than 400 infants and 41,000 adult nonsmokers every year. Learn what can be done to prevent secondhand smoke exposure.

  2. Fatigue resistance, debonding force, and failure type of fiber-reinforced composite, polyethylene ribbon-reinforced, and braided stainless steel wire lingual retainers in vitro

    NARCIS (Netherlands)

    Foek, Dave Lie Sam; Yetkiner, Enver; Ozcan, Mutlu

    Objective: To analyze the fatigue resistance, debonding force, and failure type of fiber-reinforced composite, polyethylene ribbon-reinforced, and braided stainless steel wire lingual retainers in vitro. Methods: Roots of human mandibular central incisors were covered with silicone, mimicking the

  3. Localization and force analysis at the single virus particle level using atomic force microscopy

    International Nuclear Information System (INIS)

    Liu, Chih-Hao; Horng, Jim-Tong; Chang, Jeng-Shian; Hsieh, Chung-Fan; Tseng, You-Chen; Lin, Shiming

    2012-01-01

    Highlights: ► Localization of single virus particle. ► Force measurements. ► Force mapping. -- Abstract: Atomic force microscopy (AFM) is a vital instrument in nanobiotechnology. In this study, we developed a method that enables AFM to simultaneously measure specific unbinding force and map the viral glycoprotein at the single virus particle level. The average diameter of virus particles from AFM images and the specificity between the viral surface antigen and antibody probe were integrated to design a three-stage method that sets the measuring area to a single virus particle before obtaining the force measurements, where the influenza virus was used as the object of measurements. Based on the purposed method and performed analysis, several findings can be derived from the results. The mean unbinding force of a single virus particle can be quantified, and no significant difference exists in this value among virus particles. Furthermore, the repeatability of the proposed method is demonstrated. The force mapping images reveal that the distributions of surface viral antigens recognized by antibody probe were dispersed on the whole surface of individual virus particles under the proposed method and experimental criteria; meanwhile, the binding probabilities are similar among particles. This approach can be easily applied to most AFM systems without specific components or configurations. These results help understand the force-based analysis at the single virus particle level, and therefore, can reinforce the capability of AFM to investigate a specific type of viral surface protein and its distributions.

  4. Trad. Daniele Vitale, Arquitectos portugueses. Identidade, nacionalidade, modernidade

    OpenAIRE

    Marnoto, Rita

    2010-01-01

    (2010. Trad.). Daniele Vitale, Arquitectos portugueses. Identidade, nacionalidade, modernidade, JA Jornal Arquitectos. Publicação Trimestral da Ordem dos Arquitectos Portugal, 237, 93-101. ISSN 0870 1504 Trad. Daniele Vitale

  5. VOLUME ESTIMATIONS FOR COMBINED FREE-WEIGHT AND RUBBER-BAND RESISTANCE EXERCISE

    OpenAIRE

    C. Shoepe, Todd; Vejarano, Gustavo; P. Reyes, Nathan; M. Gobreial, Nicole; M. Ricci, Jeanette

    2017-01-01

    Volume, or the total work performed during resistance training is one of the vital variables of resistance exercise programming. The most common definition in use by practitioners is sets x reps x external weight. While appropriate for linear loading incurred through free-weight resistance exercise, this inadequately addresses the nonlinear loading incurred with rubber resistance, a relatively new loading technique. The purpose of this investigation was to derive a theoretical model to descri...

  6. Organic condensation - a vital link connecting aerosol formation to climate forcing

    Science.gov (United States)

    Riipinen, I.; Pierce, J. R.; Yli-Juuti, T.; Nieminen, T.; Häkkinen, S.; Ehn, M.; Junninen, H.; Lehtipalo, K.; Petäjä, T.; Slowik, J.; Chang, R.; Shantz, N. C.; Abbatt, J.; Leaitch, W. R.; Kerminen, V.-M.; Worsnop, D. R.; Pandis, S. N.; Donahue, N. M.; Kulmala, M.

    2011-01-01

    Atmospheric aerosol particles influence global climate as well as impair air quality through their effects on atmospheric visibility and human health. Ultrafine (<100 nm) particles often dominate aerosol numbers, and nucleation of atmospheric vapors is an important source of these particles. To have climatic relevance, however, the freshly-nucleated particles need to grow in size. We combine observations from two continental sites (Egbert, Canada and Hyytiälä, Finland) to show that condensation of organic vapors is a crucial factor governing the lifetimes and climatic importance of the smallest atmospheric particles. We demonstrate that state-of-the-science organic gas-particle partitioning models fail to reproduce the observations, and propose a modeling approach that is consistent with the measurements. We demonstrate the large sensitivity of climatic forcing of atmospheric aerosols to these interactions between organic vapors and the smallest atmospheric nanoparticles - highlighting the need for representing this process in global climate models.

  7. O volume expiratório forçado no primeiro segundo não é suficiente para avaliar resposta broncodilatadora em doença pulmonar obstrutiva crônica Measuring forced expiratory volume in one second alone is not an accurate method of assessing response to bronchodilators in chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Felícia de Moraes Branco Tavares

    2005-10-01

    Full Text Available OBJETIVO: Avaliar a freqüência de variação no volume expiratório forçado no primeiro segundo após o uso de broncodilatador, em uma amostra de pacientes com doença pulmonar obstrutiva crônica. Correlacioná-la com dados clínicos e demográficos e avaliar a freqüência de resposta na capacidade vital forçada, capacidade vital lenta, capacidade inspiratória, volume residual, resistência das vias áreas e condutância das vias aéreas. MÉTODOS: Sessenta e quatro pacientes com doença pulmonar obstrutiva crônica foram submetidos a pletismografia de corpo inteiro e foi medida a reversibilidade da broncoconstrição após o uso de 400 µg de fenoterol. RESULTADOS: Tiveram resposta no volume expiratório forçado no primeiro segundo 31% dos pacientes. Excluindo-se os pacientes com resposta no volume expiratório forçado no primeiro segundo, 5% tiveram resposta em 5 dos demais parâmetros, 10% responderam em 4 parâmetros, 17,5% em 3, 27,5% em 2 e 25% em apenas 1 parâmetro. CONCLUSÃO: Os volumes pulmonares estáticos, a resistência e a condutância das vias aéreas, quando incluídos na avaliação da resposta ao broncodilatador juntamente com o volume expiratório forçado no primeiro segundo, permitem avaliar com maior amplitude o número de pacientes com resposta funcional à prova farmacodinâmica. Os resultados estão de acordo com a observação de que muitos pacientes com doença pulmonar obstrutiva crônica, mesmo sem melhora no volume expiratório forçado no primeiro segundo após o uso de broncodilatador, apresentam melhora clínica e alívio da dispnéia.OBJECTIVE: To assess the frequency of variation in forced expiratory volume in one second after bronchodilator use in a sample of patients with chronic obstructive pulmonary disease, correlating such variation with clinical and demographic variables and evaluating the frequency of response presented in forced vital capacity, slow vital capacity, inspiratory capacity

  8. [Effects of exercise and physical activity on vital age].

    Science.gov (United States)

    Tanaka, Kiyoji; Matsuo, Tomoaki

    2009-07-01

    Advances in medical care have enabled many middle-aged and older adults to live for long periods of time. However, considerable variability is present among those people with regards to both longevity and physical health status. Physical inactivity is a significant risk factor for many chronic diseases, while exercise habituation is beneficial for the maintenance of good health and high vitality. The authors have developed the concept of so-called vital age for the assessment of health and functional status in middle-aged and older adults. The vital age is estimated using a variety of bio-medical, primarily cardiovascular risk factor parameters. Previous research has compared vital age between sedentary persons and those with obesity and chronic diseases and between sedentary persons and those with exercise habituation, and found that exercise habituation can certainly contribute to better physical vitality in previously sedentary persons as well as diseased persons.

  9. Localization and force analysis at the single virus particle level using atomic force microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Chih-Hao [Institute of Applied Mechanics, Nation Taiwan University, Roosevelt Road, Taipei 10617, Taiwan (China); Horng, Jim-Tong [Department of Biochemistry, Chang Gung University, 259 Wen-Hwa First Road, Kweishan, Taoyuan 333, Taiwan (China); Chang, Jeng-Shian [Institute of Applied Mechanics, Nation Taiwan University, Roosevelt Road, Taipei 10617, Taiwan (China); Hsieh, Chung-Fan [Graduate Institute of Biomedical Sciences, Chang Gung University, Kweishan, Taoyuan 333, Taiwan (China); Tseng, You-Chen [Institute of Applied Mechanics, Nation Taiwan University, Roosevelt Road, Taipei 10617, Taiwan (China); Lin, Shiming, E-mail: til@ntu.edu.tw [Institute of Applied Mechanics, Nation Taiwan University, Roosevelt Road, Taipei 10617, Taiwan (China); Center for Optoelectronic Biomedicine, College of Medicine, Nation Taiwan University, 1-1 Jen-Ai Road, Taipei 10051, Taiwan (China)

    2012-01-06

    Highlights: Black-Right-Pointing-Pointer Localization of single virus particle. Black-Right-Pointing-Pointer Force measurements. Black-Right-Pointing-Pointer Force mapping. -- Abstract: Atomic force microscopy (AFM) is a vital instrument in nanobiotechnology. In this study, we developed a method that enables AFM to simultaneously measure specific unbinding force and map the viral glycoprotein at the single virus particle level. The average diameter of virus particles from AFM images and the specificity between the viral surface antigen and antibody probe were integrated to design a three-stage method that sets the measuring area to a single virus particle before obtaining the force measurements, where the influenza virus was used as the object of measurements. Based on the purposed method and performed analysis, several findings can be derived from the results. The mean unbinding force of a single virus particle can be quantified, and no significant difference exists in this value among virus particles. Furthermore, the repeatability of the proposed method is demonstrated. The force mapping images reveal that the distributions of surface viral antigens recognized by antibody probe were dispersed on the whole surface of individual virus particles under the proposed method and experimental criteria; meanwhile, the binding probabilities are similar among particles. This approach can be easily applied to most AFM systems without specific components or configurations. These results help understand the force-based analysis at the single virus particle level, and therefore, can reinforce the capability of AFM to investigate a specific type of viral surface protein and its distributions.

  10. Addition of non-invasive ventilatory support to combined aerobic and resistance training improves dyspnea and quality of life in heart failure patients: a randomized controlled trial.

    Science.gov (United States)

    Bittencourt, Hugo Souza; Cruz, Cristiano Gonçalves; David, Bruno Costa; Rodrigues, Erenaldo; Abade, Camille Magalhães; Junior, Roque Aras; Carvalho, Vitor Oliveira; Dos Reis, Francisco Borges Faria; Gomes Neto, Mansueto

    2017-11-01

    To test the hypothesis that combined aerobic and resistance training and non-invasive ventilatory support result in additional benefits compared with combined aerobic and resistance training alone in heart failure patients. A randomized, single-blind, controlled study. Cardiac rehabilitation center. A total of 46 patients with New York Heart Association class II/III heart failure were randomly assigned to a 10-week program of combined aerobic and resistance training, plus non-invasive ventilatory support ( n = 23) or combined aerobic and resistance training alone ( n = 23). Before and after intervention, results for the following were obtained: 6-minute walk test, forced vital capacity, forced expiratory volume at one second, maximal inspiratory muscle pressure, and maximal expiratory muscle pressure, with evaluation of dyspnea by the London Chest Activity of Daily Living scale, and quality of life with the Minnesota Living With Heart Failure questionnaire. Of the 46 included patients, 40 completed the protocol. The combined aerobic and resistance training plus non-invasive ventilatory support, as compared with combined aerobic and resistance training alone, resulted in significantly greater benefit for dyspnea (mean change: 4.8 vs. 1.3, p = 0.004), and quality of life (mean change: 19.3 vs. 6.8, p = 0.017 ). In both groups, the 6-minute walk test improved significantly (mean change: 45.7 vs. 44.1, p = 0.924), but without a statistically significant difference. Non-invasive ventilatory support combined with combined aerobic and resistance training provides additional benefits for dyspnea and quality of life in moderate heart failure patients. ClinicalTrials.gov identifier: NCT02384798. Registered 03 April 2015.

  11. A study on the force balance of an unbalanced globe valve

    International Nuclear Information System (INIS)

    Yang, Sang Min; Cho, Taik Dong; Ko, Sung Ho; Lee, Ho Young

    2007-01-01

    A pneumatic control valve is a piping element that controls the volumetric flow rate and pressure of a fluid: it is necessary to analyze the characteristics of the forces with respect to the opening of the valve in order to evaluate its operating performance. The forces occurring during operation are: resisting force and actuator force, where the load resistance is mostly affected by the fluid pressure difference of the valve. In this study, a force balance equation derived from the equilibrium relationship between the resisting force and the actuator force of an unbalanced globe valve is proposed, and the force balance equations are used to model the dynamic equations of a pneumatic unbalanced globe valve installed in nuclear power plants. A CFD analysis is also carried out to evaluate the pressure distribution and forces acting on the top and bottom planes of the valve plug. The results of this analysis have been verified through experimentation. This study has shown that the fluid pressure difference between the inlet and outlet of the valve, measured from the force balance equation of an unbalanced valve, should actually be examined with the fluid-pressure difference between the top and bottom side of the valve plug

  12. [Vital pulp therapy of damaged dental pulp].

    Science.gov (United States)

    Xuedong, Zhou; Dingming, Huang; Jianguo, Liu; Zhengwei, Huang; Xin, Wei; Deqin, Yang; Jin, Zhao; Liming, Chen; Lin, Zhu; Yanhong, Li; Jiyao, Li

    2017-08-01

    The development of an expert consensus on vital pulp therapy can provide practical guidance for the improvement of pulp damage care in China. Dental pulp disease is a major type of illness that adversely affects human oral health. Pulp capping and pulpotomy are currently the main methods for vital pulp therapy. Along with the development of minimal invasion cosmetic dentistry, using different treatment technologies and materials reasonably, preserving healthy tooth tissue, and extending tooth save time have become urgent problems that call for immediate solution in dental clinics. This paper summarizes the experiences and knowledge of endodontic experts. We develop a clinical path of vital pulp therapy for clinical work by utilizing the nature, approach, and degree of pulp damage as references, defense and self-repairing ability of pulp as guidance, and modern technologies of diagnosis and treatment as means.

  13. Aging changes in vital signs

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/004019.htm Aging changes in vital signs To use the sharing ... Normal body temperature does not change much with aging. But as you get older, it becomes harder ...

  14. Re-vitalizing an indigenous language

    DEFF Research Database (Denmark)

    Hansen, Annette Skovsted

    2014-01-01

    The re-vitalization of indigenous languages depend on political and legal support and the imple-mentation of language rights depend on knowledge of vocabulary and grammar structures of the individual languages. Throughout the nineteenth century world, compilers of dictionaries adapted indigenous...... languages to match standards defined in nation-building and, thereby, enabled latent possibilities for indigenous populations to re-vitalize their languages in connection with the United Nations Year for Indigenous Peoples in 1993, and the first United Nations Decade for Indigenous Peoples, 1995......–2004. This article focuses on dictionaries of the languages of the Ainu populations in the borderlands between the nation-states Japan and Russia. The main argument is that the Ainu Cultural Promotion Act promulgated in 1997 had a significant impact on the production and purpose of Ainu dictionaries...

  15. Vital Signs-Preventing Norovirus Outbreaks

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the June 2014 CDC Vital Signs report. Norovirus infects about 20 million Americans each year. Learn how to protect yourself and your family from this very contagious, potentially serious illness.

  16. Sideways Force Produced During Disruptions

    Science.gov (United States)

    Strauss, H. R.; Paccagnella, R.; Breslau, J.; Jardin, S.; Sugiyama, L.

    2012-10-01

    We extend previous studies [1] of vertical displacement events (VDE) which can produce disruptions. The emphasis is on the non axisymmetric ``sideways'' wall force Fx. Simulations are performed using the M3D [2] code. A VDE expels magnetic flux through the resistive wall until the last closed flux surface has q VDE is presented. The wall force depends strongly on γτw, where γ is the mode growth rate and τw is the wall resistive penetration time. The force Fx is largest when γτw is a constant of order unity, which depends on the initial conditions. For large values of γτw, the wall force asymptotes to a relatively smaller value, well below the critical value ITER is designed to withstand. The principle of disruption mitigation by massive gas injection is to cause a disruption with large γτw. [4pt] [1] H. R. Strauss, R. Paccagnella, and J. Breslau,Phys. Plasmas 17, 082505 (2010) [2] W. Park, E.V. Belova, G.Y. Fu, X. Tang, H.R. Strauss, L.E. Sugiyama, Phys. Plasmas 6, 1796 (1999).

  17. Therapeutic touch: influence on vital signs of newborns.

    Science.gov (United States)

    Ramada, Nadia Christina Oliveira; Almeida, Fabiane de Amorim; Cunha, Mariana Lucas da Rocha

    2013-12-01

    To compare vital signs before and after the therapeutic touch observed in hospitalized newborns in neonatal intensive care unit. This was a quasi-experimental study performed at a neonatal intensive care unit of a municipal hospital, in the city of São Paulo (SP), Brazil. The sample included 40 newborns submitted to the therapeutic touch after a painful procedure. We evaluated the vital signs, such as heart and respiratory rates, temperature and pain intensity, before and after the therapeutic touch. The majority of newborns were male (n=28; 70%), pre-term (n=19; 52%) and born from vaginal delivery (n=27; 67%). Respiratory distress was the main reason for hospital admission (n=16; 40%). There was a drop in all vital signs after therapeutic touch, particularly in pain score, which had a considerable reduction in the mean values, from 3.37 (SD=1.31) to 0 (SD=0.0). All differences found were statistically significant by the Wilcoxon test (ptouch promotes relaxation of the baby, favoring reduction in vital signs and, consequently in the basal metabolism rate.

  18. Effectors as Tools in Disease Resistance Breeding Against Biotrophic, Hemibiotrophic, and Necrotrophic Plant Pathogens

    NARCIS (Netherlands)

    Vleeshouwers, V.G.A.A.; Oliver, R.P.

    2014-01-01

    One of most important challenges in plant breeding is improving resistance to the plethora of pathogens that threaten our crops. The ever-growing world population, changing pathogen populations, and fungicide resistance issues have increased the urgency of this task. In addition to a vital inflow of

  19. Adiabatic and isothermal resistivities

    International Nuclear Information System (INIS)

    Fishman, R.S.

    1989-01-01

    The force-balance method is used to calculate the isothermal resistivity to first order in the electric field. To lowest order in the impurity potential, the isothermal resistivity disagrees with the adiabatic results of the Kubo formula and the Boltzmann equation. However, an expansion of the isothermal resistivity in powers of the impurity potential is divergent, with two sets of divergent terms. The first set arises from the density matrix of the relative electron-phonon system. The second set arises from the explicit dependence of the density matrix on the electric field, which was ignored by force-balance calculations. These divergent contributions are calculated inductively, by applying a recursion relation for the Green's functions. Using the λ 2 t→∞ limit of van Hove, I show that the resummation of these divergent terms yields the same result for the resistivity as the adiabatic calculations, in direct analogy with the work of Argyres and Sigel, and Huberman and Chester

  20. Dinitroaniline herbicide resistance in a multiple-resistant Lolium rigidum population.

    Science.gov (United States)

    Chen, Jinyi; Yu, Qin; Owen, Mechelle; Han, Heping; Powles, Stephen

    2018-04-01

    The pre-emergence dinitroaniline herbicides (such as trifluralin and pendimethalin) are vital to Australian no-till farming systems. A Lolium rigidum population collected from the Western Australian grain belt with a 12-year trifluralin use history was characterised for resistance to dinitroaniline, acetyl CoA carboxylase (ACCase)- and acetolactate synthase (ALS)-inhibiting herbicides. Target-site resistance mechanisms were investigated. This L. rigidum population exhibited 32-fold resistance to trifluralin, as compared with the susceptible population. It also displayed 12- to 30-fold cross-resistance to other dinitroaniline herbicides (pendimethalin, ethalfluralin and oryzalin). In addition, this population showed multiple resistance to commonly used post-emergence ACCase- and ALS-inhibiting herbicides. Two target-site α-tubulin gene mutations (Val-202-Phe and Thr-239-Ile) previously documented in other dinitroaniline-resistant weed species were identified, and some known target-site mutations in ACCase (Ile-1781-Leu, Asp-2078-Gly and Cys-2088-Arg) and ALS (Pro-197-Gln/Ser) were found in the same population. An agar-based Petri dish screening method was established for the rapid diagnosis of resistance to dinitroaniline herbicides. Evolution of target-site resistance to both pre- and post-emergence herbicides was confirmed in a single L. rigidum population. The α-tubulin mutations Val-202-Phe and Thr-239-Ile, documented here for the first time in L. rigidum, are likely to be responsible for dinitroaniline resistance in this population. Early detection of dinitroaniline herbicide resistance and integrated weed management strategies are needed to maintain the effectiveness of dinitroaniline herbicides. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  1. Analysis of lower limb force in foot work exercise of Pilates

    Directory of Open Access Journals (Sweden)

    Carolina Neis Machado

    Full Text Available Abstract Introduction: Pilates is a physical exercise method that uses the resistance of springs to modulate the overload from exercises. Objective: To characterize the force versus time curve of the foot work exercise; verify and compare the force applied by the same limb during the foot work exercise against the resistance of two types of springs with different elastic constants, and verify and compare the asymmetry of force applied by right and left lower limbs during the foot work exercise against the resistance of the same type of spring. Methods: Twenty healthy adult individuals familiarized with Pilates were evaluated. Two extensometric force plates adapted to the Reformer apparatus were used. Each participant performed 10 repetitions of the exercise against the resistance of two pairs of springs with different elastic constants. Descriptive and inferential statistics were used with significance levels of p < 0.05. Results: The exercise's standard curve showed that the peak force is reached in the point of maximum hip and knee extension during the execution of the exercise. There were differences between force production by the same limb for different springs (p < 0.001 and between left and right limb when spring with lower elastic constant was used (p = 0.006. No differences were found between right and left limb when spring with higher elastic constant was used (p = 0.108. Conclusion: The knowledge of the force versus time curve and the quantification of unilateral force are important elements in the evaluation and prescription of exercises.

  2. Vital Signs-Alcohol Poisoning Deaths

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the January 2015 CDC Vital Signs report. In the United States, an average of six people die every day from alcohol poisoning. Learn what you can do to prevent binge drinking and alcohol poisoning.

  3. Superficie Específica y Estado Vital de la Materia

    OpenAIRE

    J. Hernando Ordoñez

    1992-01-01

    Se propone reemplazar el término de materia viva por el de estado vital de la materia por considerarlo adecuado, pues la materia es la misma, lo que cambia es su estado. Se estudia la relación entre la superficie específica y el estado vital de la materia. Constante del estado vital y el valor crítico de la superficie específica. Qué es la fuerza de inducción vital? Diferenciación funcional de las células. Cómo regula la unidad biológica su superficie específica? La materia que piens...

  4. CDC Vital Signs-HIV Testing

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the December 2017 CDC Vital Signs report. In the U.S., about 15 percent of people who have HIV don't know they have it. Learn about the importance of testing, early diagnosis, and treatment.

  5. CDC Vital Signs-Legionnaires' Disease

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the June 2017 CDC Vital Signs report. Legionnaires' disease is a serious, often deadly lung infection. People most commonly get it by breathing in water droplets containing Legionella germs. Learn how to prevent infections from Legionella.

  6. Vital Signs-Secondhand Smoke

    Centers for Disease Control (CDC) Podcasts

    2015-02-03

    This podcast is based on the February 2015 CDC Vital Signs report. Secondhand smoke kills more than 400 infants and 41,000 adult nonsmokers every year. Learn what can be done to prevent secondhand smoke exposure.  Created: 2/3/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 2/3/2015.

  7. Personalidad, resiliencia y satisfacción vital

    OpenAIRE

    Solo de Zaldívar del Amo, Paloma

    2017-01-01

    El presente trabajo analiza la relación existente entre resiliencia, satisfacción vital y las variables de personalidad extraversión, neuroticismo y piscoticismo. Para ello, se utilizó una muestra de 110 sujetos, todos ellos estudiantes de psicología que completaron los cuestionarios Escala de Resiliencia (RS-18), Versión Reducida del Cuestionario Revisado de Personalidad de Eysenck (EPQ-RA-24) y Cuestionario de Satisfacción Vital (SWLS) a través de la plataforma virtual de la Universidad de ...

  8. Managing vital records in the Ghana Atomic Energy Commission

    International Nuclear Information System (INIS)

    Osei, Mary Mavis

    2004-05-01

    Several vital records can be found within the Ghana Atomic Energy Commission. Some of these records include confidential files on staff and general purpose files on staff, specialised subject files on IAEA, FAO, UN agencies etc, records on agreements from memorandum of understanding between the commission and other organisations, legislative instruments establishing the commission and its institutes and research publications. The study critically examined how these vital records at the Ghana Atomic Energy Commission were managed with the view of identifying problems and to propose actions for improvement. The specific objectives of the study was to examine methods of storage, security measures put in place to manage vital records, committment of management and staff to these measures, quality of records staff and vital records policy. Recommendations have been provided to help in the efficient and effective management of records in the commission. (A.B.)

  9. A randomized comparison of intraoperative PerfecTemp and forced-air warming during open abdominal surgery.

    Science.gov (United States)

    Egan, Cameron; Bernstein, Ethan; Reddy, Desigen; Ali, Madi; Paul, James; Yang, Dongsheng; Sessler, Daniel I

    2011-11-01

    The PerfecTemp is an underbody resistive warming system that combines servocontrolled underbody warming with viscoelastic foam pressure relief. Clinical efficacy of the system has yet to be formally evaluated. We therefore tested the hypothesis that intraoperative distal esophageal (core) temperatures with the PerfecTemp (underbody resistive) warming system are noninferior to upper-body forced-air warming in patients undergoing major open abdominal surgery under general anesthesia. Adults scheduled for elective major open abdominal surgery (liver, pancreas, gynecological, and colorectal surgery) under general anesthesia were enrolled at 2 centers. Patients were randomly assigned to underbody resistive or forced-air warming. Resistive heating started when patients were transferred to the operating room table; forced-air warming started after patients were draped. The primary outcome was noninferiority of intraoperative time-weighted average core temperature, adjusted for baseline characteristics and using a buffer of 0.5°C. Thirty-six patients were randomly assigned to underbody resistive heating and 34 to forced-air warming. Baseline and surgical characteristics were generally similar. We had sufficient evidence (P=0.018) to conclude that underbody resistive warming is not worse than (i.e., noninferior to) upper-body forced-air warming in the time-weighted average intraoperative temperature, with a mean difference of -0.12°C [95% confidence interval (CI) -0.37 to 0.14]. Core temperatures at the end of surgery averaged 36.3°C [95% CI 36 to 36.5] in the resistive warming patients and 36.6°C [95% CI 36.4 to 36.8] in those assigned to forced-air warming for a mean difference of -0.34°C [95% CI -0.69 to 0.01]. Mean intraoperative time-weighted average core temperatures were no different, and significantly noninferior, with underbody resistive heating in comparison with upper-body forced-air warming. Underbody resistive heating may be an alternative to forced

  10. Bolt Shear Force Sensor

    Science.gov (United States)

    2015-03-12

    0030] FIG. 7 is an isometric view of a deformable ring of the bolt shear force sensor of the present invention with an optical Attorney Docket No...102587 9 of 19 fiber having Bragg gratings wound around the ring; [0031] FIG. 8 is an isometric view of the deformable ring with wire strain... strength . [0047] Once the joint is subjected to an external load (see force arrows “F” and “F/2”); any frictional resistance to slip is overcome and

  11. Therapeutic touch: influence on vital signs of newborns

    Science.gov (United States)

    Ramada, Nadia Christina Oliveira; Almeida, Fabiane de Amorim; Cunha, Mariana Lucas da Rocha

    2013-01-01

    ABSTRACT Objective>: To compare vital signs before and after the therapeutic touch observed in hospitalized newborns in neonatal intensive care unit. Methods: This was a quasi-experimental study performed at a neonatal intensive care unit of a municipal hospital, in the city of São Paulo (SP), Brazil. The sample included 40 newborns submitted to the therapeutic touch after a painful procedure. We evaluated the vital signs, such as heart and respiratory rates, temperature and pain intensity, before and after the therapeutic touch. Results: The majority of newborns were male (n=28; 70%), pre-term (n=19; 52%) and born from vaginal delivery (n=27; 67%). Respiratory distress was the main reason for hospital admission (n=16; 40%). There was a drop in all vital signs after therapeutic touch, particularly in pain score, which had a considerable reduction in the mean values, from 3.37 (SD=1.31) to 0 (SD=0.0). All differences found were statistically significant by the Wilcoxon test (p<0.05). Conclusion: The results showed that therapeutic touch promotes relaxation of the baby, favoring reduction in vital signs and, consequently in the basal metabolism rate. PMID:24488378

  12. Biodegradable Piezoelectric Force Sensor.

    Science.gov (United States)

    Curry, Eli J; Ke, Kai; Chorsi, Meysam T; Wrobel, Kinga S; Miller, Albert N; Patel, Avi; Kim, Insoo; Feng, Jianlin; Yue, Lixia; Wu, Qian; Kuo, Chia-Ling; Lo, Kevin W-H; Laurencin, Cato T; Ilies, Horea; Purohit, Prashant K; Nguyen, Thanh D

    2018-01-30

    Measuring vital physiological pressures is important for monitoring health status, preventing the buildup of dangerous internal forces in impaired organs, and enabling novel approaches of using mechanical stimulation for tissue regeneration. Pressure sensors are often required to be implanted and directly integrated with native soft biological systems. Therefore, the devices should be flexible and at the same time biodegradable to avoid invasive removal surgery that can damage directly interfaced tissues. Despite recent achievements in degradable electronic devices, there is still a tremendous need to develop a force sensor which only relies on safe medical materials and requires no complex fabrication process to provide accurate information on important biophysiological forces. Here, we present a strategy for material processing, electromechanical analysis, device fabrication, and assessment of a piezoelectric Poly-l-lactide (PLLA) polymer to create a biodegradable, biocompatible piezoelectric force sensor, which only employs medical materials used commonly in Food and Drug Administration-approved implants, for the monitoring of biological forces. We show the sensor can precisely measure pressures in a wide range of 0-18 kPa and sustain a reliable performance for a period of 4 d in an aqueous environment. We also demonstrate this PLLA piezoelectric sensor can be implanted inside the abdominal cavity of a mouse to monitor the pressure of diaphragmatic contraction. This piezoelectric sensor offers an appealing alternative to present biodegradable electronic devices for the monitoring of intraorgan pressures. The sensor can be integrated with tissues and organs, forming self-sensing bionic systems to enable many exciting applications in regenerative medicine, drug delivery, and medical devices.

  13. An Efficient Vital Area Identification Method

    International Nuclear Information System (INIS)

    Jung, Woo Sik

    2017-01-01

    A new Vital Area Identification (VAI) method was developed in this study for minimizing the burden of VAI procedure. It was accomplished by performing simplification of sabotage event trees or Probabilistic Safety Assessment (PSA) event trees at the very first stage of VAI procedure. Target sets and prevention sets are calculated from the sabotage fault tree. The rooms in the shortest (most economical) prevention set are selected and protected as vital areas. All physical protection is emphasized to protect these vital areas. All rooms in the protected area, the sabotage of which could lead to core damage, should be incorporated into sabotage fault tree. So, sabotage fault tree development is a very difficult task that requires high engineering costs. IAEA published INFCIRC/225/Rev.5 in 2011 which includes principal international guidelines for the physical protection of nuclear material and nuclear installations. A new efficient VAI method was developed and demonstrated in this study. Since this method drastically reduces VAI problem size, it provides very quick and economical VAI procedure. A consistent and integrated VAI procedure had been developed by taking advantage of PSA results, and more efficient VAI method was further developed in this study by inserting PSA event tree simplification at the initial stage of VAI procedure.

  14. CDC Vital Signs-Heroin Epidemic

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the July 2015 CDC Vital Signs report. Heroin use and heroin-related overdose deaths are increasing. Most people are using it with other drugs, especially prescription opioid painkillers. Learn what can be done to prevent and treat the problem.

  15. [Discrepancies (and confluences) in perception between patients and nephrologists of chronic kidney disease impact on vital impetus in adults not undergoing hemodialysis: Results of the French MAEVA study].

    Science.gov (United States)

    Bertocchio, Jean-Philippe; Baranger, Thierry; Isnard-Rouchon, Myriam; Zaoui, Philippe; Mousson, Christiane; Deray, Gibert

    2017-12-06

    The impact of chronic kidney disease (CKD) on vital impetus is poorly documented in patients not undergoing renal dialysis and discrepancies can be observed between patients and physicians in perception of QoL and impact of the disease. A self-questionnaire was sent to 1282 French nephrologists and a mirrored self-questionnaire was given to patients (CKD stage 3, 4 or 5) by their nephrologist. Data were collected prospectively and anonymously. A total of 261 nephrologists and 172 patients participated in the survey. Sixty-six percent of patients reported a negative impact of the disease on their quality of life, which is also identified by nephrologists: important impact 22% vs 27%, mild or inconstant 44% vs 47%, mild or absent 34% vs 31% in patients and nephrologists, respectively. They had different perceptions about factors contributing to vital force; in particular, nephrologists underestimated their key role in psychological support. Indeed, the optimism and encouragements of nephrologists were considered to be a key factor of vital force for 60% of patients vs 20% of nephrologists (Padherence to treatment while mood or sexual disorders were rarely investigated. The main objective of treatment was to maintain a normal life for patients and to delay dialysis for nephrologists. Nephrologists have a relative knowledge of CKD impact on the vital impetus of patients, but there are differences of perception. It could be improved through specific trainings. Copyright © 2017 Société francophone de néphrologie, dialyse et transplantation. Published by Elsevier Masson SAS. All rights reserved.

  16. Causes and effects of vital instrumentation and control power supply bus failures

    International Nuclear Information System (INIS)

    Muhlheim, M.D.; Murphy, G.A.

    1987-01-01

    This article presents the results of a study in which the objective was to evaluate nuclear power-plant operating experience to identify the causes and the effects of vital instrumentation and control (I and C) power supply bus failures. Vital I and C power is normally provided to essential instrumentation and controls through either vital d-c or a-c power supply systems. The vital d-c power supply system generally provides control power for starting the diesel generators, for operating electrical circuit breakers, and for controlling various logic circuits. The vital d-c power system also supplies vital a-c power through an inverter. The vital a-c power supply system generally feeds the reactor protection system channels, the engineered safety features actuation system channels, and critical instrumentation in the control room. The leading cause of vital bus failures is inverter failures; other causes are human errors, battery charger failures, and miscellaneous failures. The effects of these failures are that the margin of safety can be degraded by (1) denying key information to the operators, (2) inducing plant transients, (3) causing safety injection actuations, and (4) causing the loss of shutdown cooling flow

  17. Extending role by Japanese pharmacists after training for performing vital signs monitoring

    Directory of Open Access Journals (Sweden)

    Hasegawa F

    2014-09-01

    Full Text Available Background: In Japan, the circumstances in which pharmacists work are changing. Pharmacists are expected to assess conditions of patients subject to medication to ensure proper use of pharmaceutical products. To ensure fulfilment of these roles, there have already been pharmacists’ efforts in performing vital signs monitoring. Objective: To clarify the necessity and related issues, by investigating the state of vital sign monitoring in clinical field by pharmacists who have been trained in vital sign monitoring. Method: A web survey was conducted from 4th October to 3rd December 2012, subjecting 1,026 pharmacists who completed the vital signs training hosted by The Japanese Association of Home Care Pharmacies (JAHCP. Survey items were 1 basic information of a respondent, 2 situation of homecare conducted by pharmacists, 3 seminar attendance status, and 4 vital signs monitoring status after the seminar. Results: The number of valid respondents was 430 and the response rate was 41.9%. As a result of the present research, it was revealed that 168 pharmacists (41.4%, had the opportunity to perform vital signs monitoring. By conducting vital sign monitoring, effects such as 1 improved motivation of pharmacists and better communication with patients, 2 proper use of medication, and 3 cost reduction were confirmed. Conclusion: Judging from the results of the survey, pharmacists can improve medication therapy for patients by attaining vital sign skills and conduct vital sign monitoring. Pharmacists who perform vital sign monitoring should share cases where they experienced positive patient outcomes.

  18. 12 CFR 749.4 - Format for vital records preservation.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Format for vital records preservation. 749.4... RECORDS PRESERVATION PROGRAM AND APPENDICES-RECORD RETENTION GUIDELINES; CATASTROPHIC ACT PREPAREDNESS GUIDELINES § 749.4 Format for vital records preservation. Preserved records may be in any format that can be...

  19. 46 CFR 111.51-3 - Protection of vital equipment.

    Science.gov (United States)

    2010-10-01

    ...-GENERAL REQUIREMENTS Coordination of Overcurrent Protective Devices § 111.51-3 Protection of vital equipment. (a) The coordination of overcurrent protective devices must be demonstrated for all potential... 46 Shipping 4 2010-10-01 2010-10-01 false Protection of vital equipment. 111.51-3 Section 111.51-3...

  20. Risk factors associated with multidrug-resistant tuberculosis (MDR-TB) in a tertiary armed force referral and teaching hospital, Ethiopia.

    Science.gov (United States)

    Demile, Biresaw; Zenebu, Amare; Shewaye, Haile; Xia, Siqing; Guadie, Awoke

    2018-05-31

    Ethiopia is one of the world health organization defined higher tuberculosis (TB) burden countries where the disease remains a massive public health threat. This study aimed to identify the prevalence and associated factors of multidrug-resistant tuberculosis (MDR-TB) using all armed force and civilian TB attendants in a tertiary level armed force hospital, where data for MDR-TB are previously unpublished. Cross-sectional study was conducted from September 2014 to August 2015 in a tertiary level Armed Force Referral and Teaching Hospital (AFRTH), Ethiopia. Armed force members (n = 251) and civilians (n = 130) which has been undergone TB diagnosis at AFRTH were included. All the specimens collected were subjected to microscopic smear observation, culture growth and drug susceptibility testing. Data were analyzed using statistical package for social sciences following binary logistic regression and Chi-square. P-values < 0.05 were considered statistically significant. Among 381 TB patients, 355 (93.2%) new and 26 (6.8%) retreatment cases were identified. Culture and smear positive TB cases were identified in 297 (77.9%) and 252 (66.1%) patients, respectively. The overall prevalence of MDR-TB in AFRTH was found 1.8% (1.3% for armed force members and 0.5% for civilian patients) all of which were previously TB treated cases. The entire treatment success rates were 92.6% achieved highest in the armed force (active and pension) than the civilian patients. The failure and dead cases were also found 2.5 and 4.6%, respectively. Using bivariate analysis, category of attendants and TB contact history were strong predictors of MDR-TB in armed force and civilian patients. Moreover, human immunodeficiency virus (HIV) infection also identified a significant (OR = 14.6; 95% CI = 2.3-92.1; p = 0.004) predicting factor for MDR-TB in armed force members. However, sex, age and body mass index were not associated factor for MDR-TB. In AFRTH, lower prevalence of

  1. Vital Signs-Preventing Teen Pregnancy

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the April 2015 CDC Vital Signs report. Teen births in the U.S. have declined, but still, more than 273,000 infants were born to teens ages 15 to 19 in 2013. Learn about the most effective types of birth control.

  2. Associations between VO2max and vitality in older workers: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    van der Beek Allard J

    2010-11-01

    Full Text Available Abstract Background To prevent early exit from work, it is important to study which factors contribute to healthy ageing. One concept that is assumed to be closely related to, and therefore may influence healthy ageing, is vitality. Vitality consists of both a mental and a physical component, and is characterised by a perceived high energy level, decreased feelings of fatigue, and feeling fit. Since VO2max gives an indication of one's aerobic fitness, which can be improved by increased levels of physical activity, and because feeling fit is one of the main characteristics of vitality, it is hypothesised that VO2max is related to vitality. Therefore, the aim of this study was to investigate the associations between VO2max and vitality. Methods In 427 older workers (aged 45 + years participating in the Vital@Work study, VO2max was estimated at baseline using the 2-km UKK walk test. Vitality was measured by both the UWES Vitality Scale and the RAND-36 Vitality Scale. Associations were analysed using linear regression analyses. Results The linear regression models, adjusted for age, showed a significant association between VO2max and vitality measured with the RAND-36 Vitality Scale (β = 0.446; 95% CI: 0.220-0.673. There was no significant association between VO2max and vitality measured with the UWES (β = -0.006; 95% CI:-0.017 - 0.006, after adjusting for age, gender and chronic disease status. Conclusions VO2max was associated with a general measure of vitality (measured with the RAND-36 Vitality Scale, but not with occupational health related vitality (measured with the UWES Vitality Scale. The idea that physical exercise can be used as an effective tool for improving vitality was supported in this study. Trial registration NTR1240

  3. Associations between VO2max and vitality in older workers: a cross-sectional study.

    Science.gov (United States)

    Strijk, Jorien E; Proper, Karin I; Klaver, Linda; van der Beek, Allard J; van Mechelen, Willem

    2010-11-09

    To prevent early exit from work, it is important to study which factors contribute to healthy ageing. One concept that is assumed to be closely related to, and therefore may influence healthy ageing, is vitality. Vitality consists of both a mental and a physical component, and is characterised by a perceived high energy level, decreased feelings of fatigue, and feeling fit. Since VO2max gives an indication of one's aerobic fitness, which can be improved by increased levels of physical activity, and because feeling fit is one of the main characteristics of vitality, it is hypothesised that VO2max is related to vitality. Therefore, the aim of this study was to investigate the associations between VO2max and vitality. In 427 older workers (aged 45 + years) participating in the Vital@Work study, VO2max was estimated at baseline using the 2-km UKK walk test. Vitality was measured by both the UWES Vitality Scale and the RAND-36 Vitality Scale. Associations were analysed using linear regression analyses. The linear regression models, adjusted for age, showed a significant association between VO2max and vitality measured with the RAND-36 Vitality Scale (β = 0.446; 95% CI: 0.220-0.673). There was no significant association between VO2max and vitality measured with the UWES (β = -0.006; 95% CI:-0.017 - 0.006), after adjusting for age, gender and chronic disease status. VO2max was associated with a general measure of vitality (measured with the RAND-36 Vitality Scale), but not with occupational health related vitality (measured with the UWES Vitality Scale). The idea that physical exercise can be used as an effective tool for improving vitality was supported in this study. NTR1240.

  4. Effect of current compliance and voltage sweep rate on the resistive switching of HfO2/ITO/Invar structure as measured by conductive atomic force microscopy

    International Nuclear Information System (INIS)

    Wu, You-Lin; Liao, Chun-Wei; Ling, Jing-Jenn

    2014-01-01

    The electrical characterization of HfO 2 /ITO/Invar resistive switching memory structure was studied using conductive atomic force microscopy (AFM) with a semiconductor parameter analyzer, Agilent 4156C. The metal alloy Invar was used as the metal substrate to ensure good ohmic contact with the substrate holder of the AFM. A conductive Pt/Ir AFM tip was placed in direct contact with the HfO 2 surface, such that it acted as the top electrode. Nanoscale current-voltage (I-V) characteristics of the HfO 2 /ITO/Invar structure were measured by applying a ramp voltage through the conductive AFM tip at various current compliances and ramp voltage sweep rates. It was found that the resistance of the low resistance state (RLRS) decreased with increasing current compliance value, but resistance of high resistance state (RHRS) barely changed. However, both the RHRS and RLRS decreased as the voltage sweep rate increased. The reasons for this dependency on current compliance and voltage sweep rate are discussed.

  5. Gravitational radiation resistance, radiation damping and field fluctuations

    International Nuclear Information System (INIS)

    Schaefer, G.

    1981-01-01

    Application is made of two different generalised fluctuation-dissipation theorems and their derivations to the calculation of the gravitational quadrupole radiation resistance using the radiation-reaction force given by Misner, Thorne and Wheeler (Gravitation (San Francisco: Freeman) ch 36,37 (1973)) and the usual tidal force on one hand and the tidal force and the free gravitational radiation field on the other hand. The quantum-mechanical version (including thermal generalisations) of the well known classical quadrupole radiation damping formula is obtained as a function of the radiation resistance. (author)

  6. Vital capacity and COPD: the Swedish CArdioPulmonary bioImage Study (SCAPIS

    Directory of Open Access Journals (Sweden)

    Torén K

    2016-05-01

    Full Text Available Kjell Torén,1 Anna-Carin Olin,1 Anne Lindberg,2 Jenny Vikgren,3 Linus Schiöler,1 John Brandberg,3 Åse Johnsson,3 Gunnar Engström,4 H Lennart Persson,5 Magnus Sköld,6 Jan Hedner,7 Eva Lindberg,8 Andrei Malinovschi,8 Eeva Piitulainen,9 Per Wollmer,9 Annika Rosengren,10 Christer Janson,8 Anders Blomberg,2 Göran Bergström10 1Section of Occupational and Environmental Medicine, Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 2Department of Public Health and Clinical Medicine, Division of Medicine/Respiratory Medicine, Umeå University, Umeå, 3Department of Radiology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 4Department of Clinical Science, Malmö, Lund University, Lund, 5Department of Respiratory Medicine and Department of Medicine and Health Sciences, Linköping University, Linköping, 6Respiratory Medicine Unit, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, 7Department of Internal Medicine/Lung Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 8Department of Medical Sciences, Clinical Physiology and Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, 9Department of Translational Medicine, Lund University, Malmö, 10Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Background: Spirometric diagnosis of chronic obstructive pulmonary disease (COPD is based on the ratio of forced expiratory volume in 1 second (FEV1/vital capacity (VC, either as a fixed value <0.7 or below the lower limit of normal (LLN. Forced vital capacity (FVC is a proxy for VC. The first aim was to compare the use of FVC and VC, assessed as the highest value of FVC or slow vital capacity (SVC, when assessing the FEV1/VC ratio in a general population

  7. CDC Vital Signs-Preventing Melanoma

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the June 2015 CDC Vital Signs report. Skin cancer is the most common form of cancer in the U.S. In 2011, there were more than 65,000 cases of melanoma, the most deadly form of skin cancer. Learn how everyone can help prevent skin cancer.

  8. Research on Evacuation Based on Social Force Model

    Science.gov (United States)

    Liu, W.; Deng, Z.; Li, W.; Lin, J.

    2017-09-01

    Crowded centers always cause personnel casualties in evacuation operations. Stampede events often occur by hit, squeeze and crush due to panic. It is of vital important to alleviate such situation. With the deepening of personnel evacuation research, more and more researchers are committed to study individual behaviors and self-organization phenomenon in evacuation process. The study mainly includes: 1, enrich the social force model from different facets such as visual, psychological, external force to descript more realistic evacuation; 2, research on causes and effects of self - organization phenomenon. In this paper, we focus on disorder motion that occurs in the crowded indoor publics, especially the narrow channel and safety exits and other special arteries. We put forward the improved social force model to depict pedestrians' behaviors, an orderly speed-stratification evacuation method to solve disorder problem, and shape-changed export to alleviate congestion. The result of this work shows an improvement of evacuation efficiency by 19.5 %. Guiding pedestrians' direction to slow down the influence of social forces has a guidance function in improving the efficiency of indoor emergency evacuation.

  9. The role of response force on the persistence and structure of behavior during extinction.

    Science.gov (United States)

    Pinkston, Jonathan W; Foss, Erica K

    2018-01-01

    Behavior Momentum Theory has emerged as a prominent account of resistance to change in both basic and applied research. Although laboratory studies often define precise, repeatable responses, application research often deals with response classes that may vary widely along a number of dimensions. In general, Behavior Momentum Theory has not addressed how response dimensions impact resistance to change, providing an opportunity to expand the model in new directions. Four rats pressed a force transducer under a multiple variable interval (VI) 60-s VI 60-s schedule of reinforcement. In one component, responses satisfied the schedule only if the response force fell within a "low" force band requirement; responses in the other schedule were required to satisfy a "high" force band. Once responding stabilized, extinction was programmed for three sessions. Then, the procedures were replicated. The results showed that response force came under discriminative control, but force requirements had no impact on resistance to extinction. In a follow-up condition, the schedule was changed to a multiple VI 30-s VI 120-s schedule and the low-force band operated in both components. The results showed that behavior maintained by the VI 30-s schedule was generally more resistant to extinction. A secondary analysis showed that force distributions created under baseline maintained during extinction. Overall, the results suggest that differential response force requirements prevailing in steady state do not affect the course of extinction. © 2018 Society for the Experimental Analysis of Behavior.

  10. Chiral forces and molecular dissymmetry

    International Nuclear Information System (INIS)

    Mohan, R.

    1992-01-01

    Chiral molecules leading to helical macromolecules seem to preserve information and extend it better. In the biological world RNA is the very paradigm for self-replication, elongation and autocatalytic editing. The nucleic acid itself is not chiral. It acquires its chirality by association with D-sugars. Although the chiral information or selectivity put in by the unit monomer is no longer of much interest to the biologists - they tend to leave it to the Darwinian selection principle to take care of it as illustrated by Frank's model - it is vital to understand the origin of chirality. There are three different approaches for the chiral origin of life: (1) Phenomenological, (2) Electromagnetic molecular and Coriolis forces and (3) Atomic or nuclear force, the neutral weak current. The phenomenological approach involves spontaneous symmetry breaking fluctuations in far for equilibrium systems or nucleation and crystallization. Chance plays a major role in the chiral molecule selected

  11. Theoretical research on laminar friction resistance in tubes in rolling motion

    International Nuclear Information System (INIS)

    Yan Binghuo; Yu Lei; Yang Yanhua

    2010-01-01

    The model of laminar flow in tubes in rolling motion is established. The dimensionless correlation of velocity is derived, and the correlation of frictional resistance coefficient is also obtained. Of all the additional forces, only the tangential force effects on the flow. The effect of centrifugal and Coriolis forces on the flow is counteracted. The correlation of average frictional resistance coefficient is the same with that of no rolling motion. The effect of rolling motion on frictional resistance coefficient of laminar flow diminishes with the increase of Reynolds number. (authors)

  12. Insights into the concept of vitality: associations with participation and societal costs.

    Science.gov (United States)

    van Steenbergen, E; van Dongen, J M; Wendel-Vos, G C W; Hildebrandt, V H; Strijk, J E

    2016-04-01

    In healthcare, the focus is currently shifting from someone's disabilities to someone's abilities, which is also evident from the increasing focus on vitality. Vitality (here defined as energy, motivation and resilience) is an often used concept, which also aims at someone's capabilities. However, little is known about vitality yet; in particular about its association with participation and societal costs. Within a cross-sectional design, information regarding vitality, participation and societal costs was collected among 8015 Dutch adults aged 20 years and over. Vitality was measured using the validated Dutch Vitality Questionnaire (Vita-16). Information on economic (i.e. want/able to work, work absenteeism, work performance), societal (i.e. voluntary work, informal care giving) and social participation (i.e. quantity and quality of social contacts) and societal costs (i.e. healthcare and work-related costs) was collected using an internet survey. Significant associations were found between vitality and various economic (i.e.sustainable employability:want to work: β = 1.21, 95% CI: 0.99-1.43,able to work:β = 2.09, 95% CI: 1.79-2.38;work absenteeism: OR = 0.75, 95% CI: 0.71-0.79;work performance:β = 0.49, 95% CI: 0.46-0.52), societal (i.e.voluntary work, informal care) and social (i.e.quantity and quality of social contacts) participation measures, as well as between vitality and societal costs (i.e.healthcare costs:β = -213.73, 95% CI: €-311.13 to €-107.08),absenteeism costs: β = -338.57, 95% CI: €-465.36 to €-214.14 and presenteeism costs:β = -1293.31, 95% CI: €-1492.69 to €-1088.95). This study showed significant positive associations between vitality and economic, societal and social participation and negative associations between vitality and societal costs. This may stimulate research on interventions enhancing and maintaining vitality and thereby contributing to improved participation and reduced costs. © The Author 2015. Published by

  13. Duelling Ontologies: Might Vitalism Offer Balance and Value?

    Science.gov (United States)

    Richards, Dennis; Emmanuel, Elizabeth; Grace, Sandra

    This article is part of a project investigating chiropractors' beliefs on the role of vitalism in their philosophical and practice approaches and how that might contribute to addressing current epidemics of non-communicable diseases. It aims to present atomism, reductionism, materialism and mechanism as fundamental ontologies in biomedicine and to examine what role these might play in its struggle to deal with these epidemics; to present vitalism as a fundamental ontology existing in chiropractic along with these ontologies of biomedicine; and to discuss how imbalances in the use of these ontologies and practices stemming from them might be contributing to difficulties in addressing these epidemics. The use of more balanced approaches by chiropractors involving not only mechanistic biomedical ontologies but also an increased focus on vitalism might offer value in addressing these epidemics and should be investigated. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. MEDICAL PROTECTION FOR THE EXPEDITIONARY FORCE IN THE EVENT OF USING BIOLOGICAL AGENTS

    Directory of Open Access Journals (Sweden)

    Viorel ORDEANUL

    2014-12-01

    Full Text Available The ADM/CBRN military or terrorist attack is most likely to be enforced on the force deployed in the theaters of operations (TO, as peace making troops, peace keeping troops, etc. For the medical protection of the expeditionary forces deployed in external theaters of operations (T.O., when using biological agents, we conducted a documentary study on the prophylaxis and specific treatment for the medical force protection, when using biological agents, by updating and improving the medical protection countermeasures against BWA, by anti-infective prophylaxis (antibacterial and antiviral pre-exposure, post-exposure and anti-infective etiology and support of the vital fuctions treatment.

  15. The Vitality of Disease

    OpenAIRE

    Wahlberg, Ayo

    2017-01-01

    In recent decades, social scientists have carried out empirical studies in the laboratories, clinics and patient associations within and through which biological knowledge, biomedical practice, biosocialities and biological citizens are being co-produced. In this chapter, I sketch a novel analytics of what we might be conceptualised as the vitality of disease. Medical interventions are increasingly as much about improving (quality of) life as they are about saving and prolonging life. As a co...

  16. Vital Signs - Child Passenger Safety

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the February 2014 CDC Vital Signs report. Over the past 10 years, more than 9,000 children 12 and under died in motor vehicle crashes, and a third who died in 2011 weren't buckled up. Buckling up is the best way to reduce injuries and save lives.

  17. CDC Signos Vitales-Seguridad de los camioneros (Vital Signs-Trucker Safety)

    Centers for Disease Control (CDC) Podcasts

    2015-03-03

    Este podcast se basa en la edición de marzo del 2015 del informe Signos Vitales de los CDC. En el 2012 en los Estados Unidos, ocurrieron cerca de 317 000 choques asociados a camiones pesados. Veintiséis mil camioneros y sus pasajeros sufrieron lesiones en esos choques, y cerca de 700 murieron. Infórmese sobre lo que se puede hacer para que los camioneros estén seguros.  Created: 3/3/2015 by National Institute for Occupational Safety and Health (NIOSH).   Date Released: 3/3/2015.

  18. Salt bridge interactions within the β2 integrin α7 helix mediate force-induced binding and shear resistance ability.

    Science.gov (United States)

    Zhang, Xiao; Li, Linda; Li, Ning; Shu, Xinyu; Zhou, Lüwen; Lü, Shouqin; Chen, Shenbao; Mao, Debin; Long, Mian

    2018-01-01

    The functional performance of the αI domain α 7 helix in β 2 integrin activation depends on the allostery of the α 7 helix, which axially slides down; therefore, it is critical to elucidate what factors regulate the allostery. In this study, we determined that there were two conservative salt bridge interaction pairs that constrain both the upper and bottom ends of the α 7 helix. Molecular dynamics (MD) simulations for three β 2 integrin members, lymphocyte function-associated antigen-1 (LFA-1; α L β 2 ), macrophage-1 antigen (Mac-1; α M β 2 ) and α x β 2 , indicated that the magnitude of the salt bridge interaction is related to the stability of the αI domain and the strength of the corresponding force-induced allostery. The disruption of the salt bridge interaction, especially with double mutations in both salt bridges, significantly reduced the force-induced allostery time for all three members. The effects of salt bridge interactions of the αI domain α 7 helix on β 2 integrin conformational stability and allostery were experimentally validated using Mac-1 constructs. The results demonstrated that salt bridge mutations did not alter the conformational state of Mac-1, but they did increase the force-induced ligand binding and shear resistance ability, which was consistent with MD simulations. This study offers new insight into the importance of salt bridge interaction constraints of the αI domain α 7 helix and external force for β 2 integrin function. © 2017 Federation of European Biochemical Societies.

  19. Reactor sabotage vulnerability and vital-equipment identification

    International Nuclear Information System (INIS)

    Boudreau, J.M.; Haarman, R.A.

    1982-01-01

    Two ongoing programs at Los Alamos, the Vital Area Analysis Program and the Reactor Sabotage Vulnerability Program, are discussed. The Laboratory has been providing the Nuclear Regulatory Commission with technical support in identifying the vital areas at nuclear power plants through the use of sabotage fault trees. This procedure is being expanded to provide support for the Reactor Sabotage Vulnerability Assessment Program. A re-examination of some of the original system modeling assumptions, including a survey of the applicable research, is underway. A description of the survey work and the computerized data bases being used is provided. This program is expected to result in refinements in the existing procedures

  20. HUBUNGAN PEMAKAIAN ALAT PELINDUNG PERNAPASAN DENGAN TINGKAT KAPASITAS VITAL PARU

    Directory of Open Access Journals (Sweden)

    David Eko Rikmiarif

    2012-07-01

    Full Text Available Tujuan penelitian adalah untuk mengetahui hubungan antara pemakaian alat pelindung pernapasan dengan tingkat kapasitas vital paru pada pekerja pembuat genteng di Desa Singorojo Kabupaten Jepara tahun 2011. Jenis penelitian adalah penelitian analitik yang menjelaskan korelasi antara variabel bebas dan variabel terikat. Metode yang digunakan dalam penelitian ini adalah cross sectional. Teknik penarikan sampel menggunakan total sampling. Variabel penelitian terdiri dari variabel bebas yaitu pemakaian alat pelindung pernapasan, sedangkan variabel terikat adalah kapasitas vital paru. Teknik pengumpulan data dengan metode pengukuran, kuesioner, dan dokumentasi. Metode analisis data menggunakan analisis univariat dengan analisis deskriptif dan uji bivariat dengan spearman test melalui bantuan komputer. Hasil penelitian menunjukkan bahwa nilai korelasi spearman -0,923 dengan nilai probabilitas (p value 0,0001 (< 0,05, yang artinya bahwa tidak ada hubungan yang bermakna antara pemakaian alat pelindung pernapasan dengan tingkat kapasitas vital paru pada pekerja pembuat genteng di Desa Singorojo Kabupaten Jepara tahun 2011. Simpulan penelitian adalah ada ada hubungan antara praktik penggunaan APD pernafasan (masker dengan Tingkat Kapasitas Vital Paru. The research objective was to determine the relationship between the use of respiratory protective equipment with the level of vital lung capacity in workers in the village of tile maker Singorojo Jepara regency in 2011. This type of research was the analytical research that explains the correlation between independent variables and the dependent variable. The method used in this study was cross sectional. Sampling technique using total sampling. Variable study consists of the independent variable is the use of respiratory protective equipment, while the dependent variable was the vital lung capacity. Data collection techniques with methods of measurement, questionnaires, and documentation. Methods of data

  1. Spiritual Development for Strategic Leadership in the Air Force

    Science.gov (United States)

    2010-03-01

    in their article “The Domain of the Human Spirit,” define spirit as “the vital animating force within living beings; the part of a human being... supernatural .”24 Careful examination shows the two terms are distinct and should not be used interchangeably. One such example of implying that religion and...interpreted as not allowing spiritual development. Fitzkee and Letendre’s 11 article “Religion in the Military: Navigating the Channel Between the

  2. Vital Signs-Preventing Norovirus Outbreaks

    Centers for Disease Control (CDC) Podcasts

    2014-06-03

    This podcast is based on the June 2014 CDC Vital Signs report. Norovirus infects about 20 million Americans each year. Learn how to protect yourself and your family from this very contagious, potentially serious illness.  Created: 6/3/2014 by National Center for Immunization and Respiratory Diseases (NCIRD).   Date Released: 6/3/2014.

  3. Monitor portátil de signos vitales con un PDA

    OpenAIRE

    Rodríguez Salazar, Rita Beatriz

    2007-01-01

    El monitor portátil de signos vitales facilita el proceso de medición y lleva un registro organizado de los valores medidos. Los signos vitales que se contempla son la temperatura corporal, la presión arterial y la frecuencia cardiaca.Para la medición de estos signos vitales se utilizan los sensores respectivos y se realiza el acondicionamiento de señal. Estas señales son procesadas en un PDA en el que también se visualiza los valores obtenidos en la medición y se registra estos datos si el u...

  4. Vital pulp therapy in symptomatic immature permanent molars: Report of 3 cases

    Directory of Open Access Journals (Sweden)

    SheikhRezaie MS.

    2009-11-01

    Full Text Available "nEndodontic treatment of immature permanent teeth accompanies with several issues. The primary goal when treating such teeth is to maintain pulp vitality so that root development can occur normally. Indications and requirements for vital pulp therapy include asymptomatic and reversible pulpitis. Also there are controversial opinions regarding the ultimate clinical treatment of the vital pulp therapy techniques. In this manuscript we report 3 cases of immature symptomatic permanent molars with irreversible pulpitis caused by caries exposure of the pulp that have been undergone vital pulp therapy successfully.

  5. DistancePPG: Robust non-contact vital signs monitoring using a camera

    Science.gov (United States)

    Kumar, Mayank; Veeraraghavan, Ashok; Sabharwal, Ashutosh

    2015-01-01

    Vital signs such as pulse rate and breathing rate are currently measured using contact probes. But, non-contact methods for measuring vital signs are desirable both in hospital settings (e.g. in NICU) and for ubiquitous in-situ health tracking (e.g. on mobile phone and computers with webcams). Recently, camera-based non-contact vital sign monitoring have been shown to be feasible. However, camera-based vital sign monitoring is challenging for people with darker skin tone, under low lighting conditions, and/or during movement of an individual in front of the camera. In this paper, we propose distancePPG, a new camera-based vital sign estimation algorithm which addresses these challenges. DistancePPG proposes a new method of combining skin-color change signals from different tracked regions of the face using a weighted average, where the weights depend on the blood perfusion and incident light intensity in the region, to improve the signal-to-noise ratio (SNR) of camera-based estimate. One of our key contributions is a new automatic method for determining the weights based only on the video recording of the subject. The gains in SNR of camera-based PPG estimated using distancePPG translate into reduction of the error in vital sign estimation, and thus expand the scope of camera-based vital sign monitoring to potentially challenging scenarios. Further, a dataset will be released, comprising of synchronized video recordings of face and pulse oximeter based ground truth recordings from the earlobe for people with different skin tones, under different lighting conditions and for various motion scenarios. PMID:26137365

  6. Development of Magnetorheological Resistive Exercise Device for Rowing Machine

    Directory of Open Access Journals (Sweden)

    Vytautas Grigas

    2016-01-01

    Full Text Available Training equipment used by professional sportsmen has a great impact on their sport performance. Most universal exercisers may help only to improve the general physical condition due to the specific kinematics and peculiar resistance generated by their loading units. Training of effective techniques and learning of psychomotor skills are possible only when exercisers conform to the movements and resistance typical for particular sports kinematically and dynamically. Methodology of developing a magnetorheological resistive exercise device for generating the desired law of passive resistance force and its application in a lever-type rowing machine are described in the paper. The structural parameters of a controllable hydraulic cylinder type device were found by means of the computational fluid dynamics simulation performed by ANSYS CFX software. Parameters describing the magnetorheological fluid as non-Newtonian were determined by combining numerical and experimental research of the resistance force generated by the original magnetorheological damper. A structural scheme of the device control system was developed and the variation of the strength of magnetic field that affects the magnetorheological fluid circulating in the device was determined, ensuring a variation of the resistance force on the oar handle adequate for the resistance that occurs during a real boat rowing stroke.

  7. Mediating Role of Mindfulness on the Associations of Friendship Quality and Subjective Vitality.

    Science.gov (United States)

    Akin, Umran; Akin, Ahmet; Uğur, Erol

    2016-10-01

    This research investigated the mediator role of mindfulness on the relationship between friendship quality and subjective vitality. Participants were 273 university students (M age = 21 years, SD = 1.1) who completed a questionnaire package that included the Friendship Quality Scale, the Cognitive and Affective Mindfulness Scale, and the Subjective Vitality Scale. Both mindfulness and subjective vitality were correlated positively with friendship quality and subjective vitality was correlated positively with mindfulness. Mindfulness mediated the relationship between friendship quality and subjective vitality. Together, the findings illuminate the importance of friendship quality in psychological and cognitive adjustment. © The Author(s) 2016.

  8. Lorentz force actuation of a heated atomic force microscope cantilever.

    Science.gov (United States)

    Lee, Byeonghee; Prater, Craig B; King, William P

    2012-02-10

    We report Lorentz force-induced actuation of a silicon microcantilever having an integrated resistive heater. Oscillating current through the cantilever interacts with the magnetic field around a NdFeB permanent magnet and induces a Lorentz force that deflects the cantilever. The same current induces cantilever heating. With AC currents as low as 0.2 mA, the cantilever can be oscillated as much as 80 nm at resonance with a DC temperature rise of less than 5 °C. By comparison, the AC temperature variation leads to a thermomechanical oscillation that is about 1000 times smaller than the Lorentz deflection at the cantilever resonance. The cantilever position in the nonuniform magnetic field affects the Lorentz force-induced deflection, with the magnetic field parallel to the cantilever having the largest effect on cantilever actuation. We demonstrate how the cantilever actuation can be used for imaging, and for measuring the local material softening temperature by sensing the contact resonance shift.

  9. CDC Vital Signs: Preventing Teen Pregnancy

    Science.gov (United States)

    ... Press Kit Read the MMWR Science Clips Preventing Teen Pregnancy A Key Role for Health Care Providers Language: ... Battles: Teen Pregnancy Prevention Status Reports (PSRs): Teen Pregnancy FastStats: Teen Births Vital Signs – Preventing Teen Pregnancy [PODCAST – 1: ...

  10. CDC Vital Signs-Preventing Stroke Deaths

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the September 2017 CDC Vital Signs report. Each year, more than 140,000 people die and many survivors face disability. Eighty percent of strokes are preventable. Learn the signs of stroke and how to prevent them.

  11. Vital directions for mathematics education research

    CERN Document Server

    Leatham, Keith R

    2013-01-01

    In this book, experts discuss vital issues in mathematics education and what they see as viable directions for research in mathematics education to address them. Their recommendations take the form of overarching principles and ideas that cut across the field.

  12. Vital Signs-Trucker Safety

    Centers for Disease Control (CDC) Podcasts

    2015-03-03

    This podcast is based on the March 2015 CDC Vital Signs report. In 2012 in the United States, about 317,000 motor vehicle crashes involved a large truck. Twenty-six thousand truck drivers and their passengers were injured in these crashes, and about 700 died. Learn what can be done to help truck drivers stay safe.  Created: 3/3/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 3/3/2015.

  13. Bacterial strategies of resistance to antimicrobial peptides.

    Science.gov (United States)

    Joo, Hwang-Soo; Fu, Chih-Iung; Otto, Michael

    2016-05-26

    Antimicrobial peptides (AMPs) are a key component of the host's innate immune system, targeting invasive and colonizing bacteria. For successful survival and colonization of the host, bacteria have a series of mechanisms to interfere with AMP activity, and AMP resistance is intimately connected with the virulence potential of bacterial pathogens. In particular, because AMPs are considered as potential novel antimicrobial drugs, it is vital to understand bacterial AMP resistance mechanisms. This review gives a comparative overview of Gram-positive and Gram-negative bacterial strategies of resistance to various AMPs, such as repulsion or sequestration by bacterial surface structures, alteration of membrane charge or fluidity, degradation and removal by efflux pumps.This article is part of the themed issue 'Evolutionary ecology of arthropod antimicrobial peptides'. © 2016 The Author(s).

  14. Quantification of the resist dissolution process: an in situ analysis using high speed atomic force microscopy

    Science.gov (United States)

    Santillan, Julius Joseph; Shichiri, Motoharu; Itani, Toshiro

    2016-03-01

    This work focuses on the application of a high speed atomic force microscope (HS-AFM) for the in situ visualization / quantification of the resist dissolution process. This technique, as reported in the past, has provided useful pointers on the formation of resist patterns during dissolution. This paper discusses about an investigation made on the quantification of what we refer to as "dissolution unit size" or the basic units of patterning material dissolution. This was done through the establishment of an originally developed analysis method which extracts the difference between two succeeding temporal states of the material film surface (images) to indicate the amount of change occurring in the material film at a specific span of time. Preliminary experiments with actual patterning materials were done using a positive-tone EUV model resist composed only of polyhydroxystyrene (PHS)-based polymer with a molecular weight of 2,500 and a polydispersity index of 1.2. In the absence of a protecting group, the material was utilized at a 50nm film thickness with post application bake of 90°C/60s. The resulting film is soluble in the alkali-based developer even without exposure. Results have shown that the dissolution components (dissolution unit size) of the PHS-based material are not of fixed size. Instead, it was found that aside from one constantly dissolving unit size, another, much larger dissolution unit size trend also occurs during material dissolution. The presence of this larger dissolution unit size suggests an occurrence of "polymer clustering". Such polymer clustering was not significantly present during the initial stages of dissolution (near the original film surface) but becomes more persistently obvious after the dissolution process reaches a certain film thickness below the initial surface.

  15. Vital Signs-Preventing Prescription Drug Overdose

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the July 2014 CDC Vital Signs report. Every day, 46 people in the U.S. die from an overdose of prescription opioid painkillers. Learn what can be done to make painkiller prescribing safer and help prevent overdoses.

  16. The Economic Vitality Formula of Success

    Science.gov (United States)

    Konopnicki, Patrick M.

    2012-01-01

    An economic vitality formula of success can be accomplished by creating partnerships between local career and technical education (CTE), and workforce development and economic development entities. Student industry certifications; dynamic partnerships; programs and projects focused on science, technology, engineering, and mathematics (STEM); and…

  17. Vital Signs-Alcohol Poisoning Deaths

    Centers for Disease Control (CDC) Podcasts

    2015-01-06

    This podcast is based on the January 2015 CDC Vital Signs report. In the United States, an average of six people die every day from alcohol poisoning. Learn what you can do to prevent binge drinking and alcohol poisoning.  Created: 1/6/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 1/6/2015.

  18. Evaluation of Force-Time Changes During Impact of Hybrid Laminates Made of Titanium and Fibrous Composite

    Directory of Open Access Journals (Sweden)

    Jakubczak P.

    2016-06-01

    Full Text Available Fibre metal laminates (FML are the modern hybrid materials with potential wide range of applications in aerospace technology due to their excellent mechanical properties (particularly fatigue strength, resistance to impacts and also excellent corrosion resistance. The study describes the resistance to low velocity impacts in Ti/CFRP laminates. Tested laminates were produced in autoclave process. The laminates were characterized in terms of their response to impacts in specified energy range (5J, 10J, 20J. The tests were performed in accordance with ASTM D7137 standard. The laminates were subjected to impacts by means of hemispherical impactor with diameter of 12,7 mm. The following values have been determined: impact force vs. time, maximum force and the force at which the material destruction process commences (Pi. It has been found that fibre titanium laminates are characterized by high resistance to impacts. This feature is associated with elasto-plastic properties of metal and high rigidity of epoxy - fibre composite. It has been observed that Ti/CFRP laminates are characterized by more instable force during impact in stage of stabilization of impactor-laminate system and stage of force growth that glass fibre laminates. It has been observed more stable force decrease in stage of stress relaxation and withdrawal of the impactor. In energy range under test, the laminates based on titanium with glass and carbon fibres reinforcement demonstrate similar and high resistance to low-velocity impact, measured by means of failure initiation force and impact maximum force.

  19. Effects of clamping force on the water transport and performance of a PEM (proton electrolyte membrane) fuel cell with relative humidity and current density

    International Nuclear Information System (INIS)

    Cha, Dowon; Ahn, Jae Hwan; Kim, Hyung Soon; Kim, Yongchan

    2015-01-01

    The clamping force should be applied to a proton electrolyte membrane (PEM) fuel cell due to its structural characteristics. The clamping force affects the ohmic and mass transport resistances in the PEM fuel cell. In this study, the effects of the clamping force on the water transport and performance characteristics of a PEM fuel cell are experimentally investigated with variations in the relative humidity and current density. The water transport characteristics were analyzed by calculating the net drag coefficient. The ohmic resistance decreased with the increase in the clamping force due to the reduced contact resistance and more even membrane hydration. However, the mass transport resistance increased with the increase in the clamping force due to the gas diffusion layer compression. The net drag coefficient decreased with the increase in the clamping force due to high water back-diffusion. Additionally, the relationship between the total resistance and the net drag coefficient was investigated. - Highlights: • Effects of clamping force on the performance of a PEM fuel cell are investigated. • Water transport characteristics are analyzed using net drag coefficient. • Ohmic resistance decreased with clamping force, but mass transport resistance increased. • Net drag coefficient decreased with the increase in clamping force. • Total resistance was significantly degraded for a net drag coefficient below 0.2.

  20. Pulmonary function in men after oxygen breathing at 3.0 ATA for 3.5 h

    Science.gov (United States)

    Clark, J. M.; Jackson, R. M.; Lambertsen, C. J.; Gelfand, R.; Hiller, W. D. B.; Unger, M.

    1991-01-01

    A complete description of pulmonary measurements obtained after continuous O2 exposure of 13 healthy men at 3.0 ATA for 3.5 h is presented. Measurements included flow-volume loops, spirometry, and airway resistance(n = 12); CO diffusing capacity (n = 11); closing volumes (n= 6); and air vs. HeO2 forced vital capacity maneuvers (n = 5). The average difference in maximum mid expiratory flows at 50 percent vital capacity on air and HeO2 was found to be significantly reduced postexposure by 18 percent. Raw and CO diffusing capacity were not changed postexposure. It is concluded that the relatively large change in forced expiratory flow at 25-75 percent of vital capacity compared with the mean forced expiratory volume in 1 s, the reduction in density dependence of flow, and the normal Raw postexposure are all consistent with flow limitation in peripheral airways as a major cause of the observed reduction in expiratory flow.

  1. Investigation of the heparin-thrombin interaction by dynamic force spectroscopy.

    Science.gov (United States)

    Wang, Congzhou; Jin, Yingzi; Desai, Umesh R; Yadavalli, Vamsi K

    2015-06-01

    The interaction between heparin and thrombin is a vital step in the blood (anti)coagulation process. Unraveling the molecular basis of the interactions is therefore extremely important in understanding the mechanisms of this complex biological process. In this study, we use a combination of an efficient thiolation chemistry of heparin, a self-assembled monolayer-based single molecule platform, and a dynamic force spectroscopy to provide new insights into the heparin-thrombin interaction from an energy viewpoint at the molecular scale. Well-separated single molecules of heparin covalently attached to mixed self-assembled monolayers are demonstrated, whereby interaction forces with thrombin can be measured via atomic force microscopy-based spectroscopy. Further these interactions are studied at different loading rates and salt concentrations to directly obtain kinetic parameters. An increase in the loading rate shows a higher interaction force between the heparin and thrombin, which can be directly linked to the kinetic dissociation rate constant (koff). The stability of the heparin/thrombin complex decreased with increasing NaCl concentration such that the off-rate was found to be driven primarily by non-ionic forces. These results contribute to understanding the role of specific and nonspecific forces that drive heparin-thrombin interactions under applied force or flow conditions. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Vital and dispensable roles of Plasmodium multidrug resistance transporters during blood- and mosquito-stage development

    NARCIS (Netherlands)

    Rijpma, S.R.; Velden, M. van der; Annoura, T.; Matz, J.M.; Kenthirapalan, S.; Kooij, T.W.; Matuschewski, K.; Gemert, G.J.A. van; Vegte-Bolmer, M.G. van de; Siebelink-Stoter, R.; Graumans, W.; Ramesar, J.; Klop, O.; Russel, F.G.; Sauerwein, R.W.; Janse, C.J.; Franke-Fayard, B.M.; Koenderink, J.B.

    2016-01-01

    Multidrug resistance (MDR) proteins belong to the B subfamily of the ATP Binding Cassette (ABC) transporters, which export a wide range of compounds including pharmaceuticals. In this study, we used reverse genetics to study the role of all seven Plasmodium MDR proteins during the life cycle of

  3. Effects of adding whole body vibration to squat training on isometric force/time characteristics.

    Science.gov (United States)

    Lamont, Hugh S; Cramer, Joel T; Bemben, Debra A; Shehab, Randa L; Anderson, Mark A; Bemben, Michael G

    2010-01-01

    Resistance training interventions aimed at increasing lower-body power and rates of force development have produced varying results. Recent studies have suggested that whole-body low-frequency vibration (WBLFV) may elicit an acute postactivation potentiation response, leading to acute improvements in power and force development. Potentially, the use of WBLFV between sets of resistance training rather than during training itself may lead to increased recruitment and synchronization of high-threshold motor units, minimize fatigue potential, and facilitate the chronic adaptation to resistance exercise. The purpose of this study was to determine the effects of applying TriPlaner, WBLFV, prior to and then intermittently between sets of Smith machine squats on short-term adaptations in explosive isometric force expression. Thirty recreationally resistance trained men aged 18-30 were randomly assigned to 1 of 3 groups: resistance training only (SQT, n = 11), resistance plus whole-body vibration (SQTV, n = 13), or active control (CON, n = 6). An isometric squat test was performed prior to and following a 6-week periodized Smith machine squat program. Whole-body low-frequency vibration was applied 180 seconds prior to the first work set (50 Hz, 2-4 mm, 30 seconds) and intermittently (50 Hz, 4-6 mm, 3 x 10 seconds, 60 seconds between exposures) within a 240-second interset rest period. Subjects were instructed to assume a quarter squat posture while positioning their feet directly under their center of mass, which was modified using a handheld goniometer to a knee angle of 135 +/- 5 degrees . Instructions were given to subjects to apply force as fast and as hard as possible for 3.5 seconds. Isometric force (N) and rates of force development (N.s(-1)) were recorded from the onset of contraction (F(0)) to time points corresponding to 30, 50, 80, 100, 150, and 250 milliseconds, as well as the peak isometric rate of force development (PISORFD), and rate of force development to

  4. Validity and reliability of a controlled pneumatic resistance exercise device.

    Science.gov (United States)

    Paulus, David C; Reynolds, Michael C; Schilling, Brian K

    2008-01-01

    During the concentric portion of the free-weight squat exercise, accelerating the mass from rest results in a fluctuation in ground reaction force. It is characterized by an initial period of force greater than the load while accelerating from rest followed by a period of force lower than the external load during negative acceleration. During the deceleration phase, less force is exerted and muscles are loaded sub-optimally. Thus, using a reduced inertia form of resistance such as pneumatics has the capability to minimize these inertial effects as well as control the force in real time to maximize the force exerted over the exercise cycle. To improve the system response of a preliminary design, a squat device was designed with a reduced mass barbell and two smaller pneumatic cylinders. The resistance was controlled by regulating cylinder pressure such that it is capable of adjusting force within a repetition to maximize force exerted during the lift. The resistance force production of the machine was statically validated with the input voltage and output force R2 =0.9997 for at four increments of the range of motion, and the intraclass correlation coefficient (ICC) between trials at the different heights equaled 0.999. The slew rate at three forces was 749.3 N/s +/- 252.3. Dynamic human subject testing showed the desired input force correlated with average and peak ground reaction force with R2 = 0.9981 and R2 = 0.9315, respectively. The ICC between desired force and average and peak ground reaction force was 0.963. Thus, the system is able to deliver constant levels of static and dynamic force with validity and reliability. Future work will be required to develop the control strategy required for real-time control, and performance testing is required to determine its efficacy.

  5. Relationships between vital rates and ecological traits in an avian community.

    Science.gov (United States)

    Bellier, Edwige; Kéry, Marc; Schaub, Michael

    2018-03-30

    Comparative studies about the relationships between vital rates and ecological traits at the community level are conspicuously lacking for most taxa because estimating vital rates requires detailed demographic data. Identifying relationships between vital rates and ecological traits could help to better understand ecological and evolutionary demographic mechanisms that lead to interspecific differences in vital rates. We use novel dynamic N-mixture models for counts to achieve this for a whole avian community comprising 53 passerine species, while simultaneously accounting for density dependence and environmental stochasticity in recruitment and survival and, importantly, correcting our inferences for imperfect detection. Demographic stochasticity is taken into account in the form of the binomial and Poisson distributions describing survival events and number of recruits. We then explore relationships between estimated demographic parameters (i.e., vital rates) and ecological traits related to migration patterns, diet, habitat and nesting location of each species. The relative importance of recruitment and adult survival as contributors to population growth varied greatly among species, and interspecific differences in vital rates partly reflected differences in ecological traits. Migratory mode was associated with interspecific differences in population growth and density dependence. Resident species had higher population growth rates than long- and short-distance migrants. We found no relationships between diet and population growth rate. Habitat differences were associated with different growth rates: alpine, wetland and farmland species had lower population growth rates than forest species. Differences in population growth rates among nesting locations showed that breeding habitat is essential for population dynamics. Our study reveals relationships between ecological traits and contributions of vital rates to population growth and suggests ways in which

  6. Vitality Forms Processing in the Insula during Action Observation: A Multivoxel Pattern Analysis.

    Science.gov (United States)

    Di Cesare, Giuseppe; Valente, Giancarlo; Di Dio, Cinzia; Ruffaldi, Emanuele; Bergamasco, Massimo; Goebel, Rainer; Rizzolatti, Giacomo

    2016-01-01

    Observing the style of an action done by others allows the observer to understand the cognitive state of the agent. This information has been defined by Stern "vitality forms". Previous experiments showed that the dorso-central insula is selectively active both during vitality form observation and execution. In the present study, we presented participants with videos showing hand actions performed with different velocities and asked them to judge either their vitality form (gentle, neutral, rude) or their velocity (slow, medium, fast). The aim of the present study was to assess, using multi-voxel pattern analysis, whether vitality forms and velocities of observed goal-directed actions are differentially processed in the insula, and more specifically whether action velocity is encoded per se or it is an element that triggers neural populations of the insula encoding the vitality form. The results showed that, consistently across subjects, in the dorso-central sector of the insula there were voxels selectively tuned to vitality forms, while voxel tuned to velocity were rare. These results indicate that the dorso-central insula, which previous data showed to be involved in the vitality form processing, contains voxels specific for the action style processing.

  7. Vitality Forms Processing in the Insula during Action Observation: A Multivoxel Pattern Analysis

    Science.gov (United States)

    Di Cesare, Giuseppe; Valente, Giancarlo; Di Dio, Cinzia; Ruffaldi, Emanuele; Bergamasco, Massimo; Goebel, Rainer; Rizzolatti, Giacomo

    2016-01-01

    Observing the style of an action done by others allows the observer to understand the cognitive state of the agent. This information has been defined by Stern “vitality forms”. Previous experiments showed that the dorso-central insula is selectively active both during vitality form observation and execution. In the present study, we presented participants with videos showing hand actions performed with different velocities and asked them to judge either their vitality form (gentle, neutral, rude) or their velocity (slow, medium, fast). The aim of the present study was to assess, using multi-voxel pattern analysis, whether vitality forms and velocities of observed goal-directed actions are differentially processed in the insula, and more specifically whether action velocity is encoded per se or it is an element that triggers neural populations of the insula encoding the vitality form. The results showed that, consistently across subjects, in the dorso-central sector of the insula there were voxels selectively tuned to vitality forms, while voxel tuned to velocity were rare. These results indicate that the dorso-central insula, which previous data showed to be involved in the vitality form processing, contains voxels specific for the action style processing. PMID:27375461

  8. Validating emergency department vital signs using a data quality engine for data warehouse.

    Science.gov (United States)

    Genes, N; Chandra, D; Ellis, S; Baumlin, K

    2013-01-01

    Vital signs in our emergency department information system were entered into free-text fields for heart rate, respiratory rate, blood pressure, temperature and oxygen saturation. We sought to convert these text entries into a more useful form, for research and QA purposes, upon entry into a data warehouse. We derived a series of rules and assigned quality scores to the transformed values, conforming to physiologic parameters for vital signs across the age range and spectrum of illness seen in the emergency department. Validating these entries revealed that 98% of free-text data had perfect quality scores, conforming to established vital sign parameters. Average vital signs varied as expected by age. Degradations in quality scores were most commonly attributed logging temperature in Fahrenheit instead of Celsius; vital signs with this error could still be transformed for use. Errors occurred more frequently during periods of high triage, though error rates did not correlate with triage volume. In developing a method for importing free-text vital sign data from our emergency department information system, we now have a data warehouse with a broad array of quality-checked vital signs, permitting analysis and correlation with demographics and outcomes.

  9. CDC Vital Signs-Heroin Epidemic

    Centers for Disease Control (CDC) Podcasts

    2015-07-07

    This podcast is based on the July 2015 CDC Vital Signs report. Heroin use and heroin-related overdose deaths are increasing. Most people are using it with other drugs, especially prescription opioid painkillers. Learn what can be done to prevent and treat the problem.  Created: 7/7/2015 by National Center for Injury Prevention and Control (NCIPC).   Date Released: 7/7/2015.

  10. Connecting HRM and Change Management: The Importance of Proactivity and Vitality

    NARCIS (Netherlands)

    L.G. Tummers (Lars); P.M. Kruyen; D. Vijverberg (Dominique); T. Voesenek (Tessa)

    2014-01-01

    markdownabstract__Abstract__ __Purpose__: Organizations are continuously under pressure to adapt to changing circumstances. Job proactivity and vitality are important in changing environments. For instance, vital employees can better deal with change because they possess more energy. However, it

  11. Effects of adenosine triphosphate concentration on motor force regulation during skeletal muscle contraction

    Science.gov (United States)

    Wei, J.; Dong, C.; Chen, B.

    2017-04-01

    We employ a mechanical model of sarcomere to quantitatively investigate how adenosine triphosphate (ATP) concentration affects motor force regulation during skeletal muscle contraction. Our simulation indicates that there can be negative cross-bridges resisting contraction within the sarcomere and higher ATP concentration would decrease the resistance force from negative cross-bridges by promoting their timely detachment. It is revealed that the motor force is well regulated only when ATP concentration is above a certain level. These predictions may provide insights into the role of ATP in regulating coordination among multiple motors.

  12. CDC Vital Signs-Cancer and Obesity

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the October 2017 CDC Vital Signs report. Obesity is a leading cancer risk factor. Unfortunately, two out of three U.S. adults weigh more than recommended. Find out what can be done to help people get to and keep a healthy weight.

  13. Note: A rigid piezo motor with large output force and an effective method to reduce sliding friction force

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Ying; Lu, Qingyou, E-mail: qxl@ustc.edu.cn [High Magnetic Field Laboratory, Chinese Academy of Sciences and University of Science and Technology of China, Hefei, Anhui 230026 (China); Hefei National Laboratory for Physical Sciences at Microscale, University of Science and Technology of China, Hefei, Anhui 230026 (China); Hou, Yubin [High Magnetic Field Laboratory, Chinese Academy of Sciences and University of Science and Technology of China, Hefei, Anhui 230026 (China)

    2014-05-15

    We present a completely practical TunaDrive piezo motor. It consists of a central piezo stack sandwiched by two arm piezo stacks and two leg piezo stacks, respectively, which is then sandwiched and spring-clamped by a pair of parallel polished sapphire rods. It works by alternatively fast expanding and contracting the arm/leg stacks while slowly expanding/contracting the central stack simultaneously. The key point is that sufficiently fast expanding and contracting a limb stack can make its two sliding friction forces well cancel, resulting in the total sliding friction force is <10% of the total static friction force, which can help increase output force greatly. The piezo motor's high compactness, precision, and output force make it perfect in building a high-quality harsh-condition (vibration resistant) atomic resolution scanning probe microscope.

  14. Note: A rigid piezo motor with large output force and an effective method to reduce sliding friction force

    International Nuclear Information System (INIS)

    Guo, Ying; Lu, Qingyou; Hou, Yubin

    2014-01-01

    We present a completely practical TunaDrive piezo motor. It consists of a central piezo stack sandwiched by two arm piezo stacks and two leg piezo stacks, respectively, which is then sandwiched and spring-clamped by a pair of parallel polished sapphire rods. It works by alternatively fast expanding and contracting the arm/leg stacks while slowly expanding/contracting the central stack simultaneously. The key point is that sufficiently fast expanding and contracting a limb stack can make its two sliding friction forces well cancel, resulting in the total sliding friction force is <10% of the total static friction force, which can help increase output force greatly. The piezo motor's high compactness, precision, and output force make it perfect in building a high-quality harsh-condition (vibration resistant) atomic resolution scanning probe microscope

  15. Axes of resistance for tooth movement: does the center of resistance exist in 3-dimensional space?

    Science.gov (United States)

    Viecilli, Rodrigo F; Budiman, Amanda; Burstone, Charles J

    2013-02-01

    The center of resistance is considered the most important reference point for tooth movement. It is often stated that forces through this point will result in tooth translation. The purpose of this article is to report the results of numeric experiments testing the hypothesis that centers of resistance do not exist in space as 3-dimensional points, primarily because of the geometric asymmetry of the periodontal ligament. As an alternative theory, we propose that, for an arbitrary tooth, translation references can be determined by 2-dimensional projection intersections of 3-dimensional axes of resistance. Finite element analyses were conducted on a maxillary first molar model to determine the position of the axes of rotation generated by 3-dimensional couples. Translation tests were performed to compare tooth movement by using different combinations of axes of resistance as references. The couple-generated axes of rotation did not intersect in 3 dimensions; therefore, they do not determine a 3-dimensional center of resistance. Translation was obtained by using projection intersections of the 2 axes of resistance perpendicular to the force direction. Three-dimensional axes of resistance, or their 2-dimensional projection intersections, should be used to plan movement of an arbitrary tooth. Clinical approximations to a small 3-dimensional "center of resistance volume" might be adequate in nearly symmetric periodontal ligament cases. Copyright © 2013 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  16. The Vitality of Disease

    DEFF Research Database (Denmark)

    Wahlberg, Ayo

    2017-01-01

    of what we might be conceptualised as the vitality of disease. Medical interventions are increasingly as much about improving (quality of) life as they are about saving and prolonging life. As a consequence, morbid living has come to be disciplined, for example, in patient schools aimed at teaching...... patients to learn how to live with their disease, through rating scales used to measure treatment effect on the ‘quality of life’ of patients in clinical trials and through disease-specific ‘Living with’ guides aimed at patients and carers....

  17. Increasing incidence of fluoroquinolone-resistant Mycobacterium tuberculosis in Mumbai, India.

    Science.gov (United States)

    Agrawal, D; Udwadia, Z F; Rodriguez, C; Mehta, A

    2009-01-01

    Tertiary referral centre, private hospital, Mumbai, India. To analyse the incidence of fluoroquinolone (FQ) resistant Mycobacterium tuberculosis (TB) in our laboratory from 1995 to 2004. Retrospective review and analysis of the drug susceptibility test records of all M. tuberculosis culture-positive samples from our Microbiology Department from 1995 to 2004. FQ resistance has increased exponentially in our laboratory, from 3% in 1996 to 35% in 2004. The incidence of multidrug-resistant tuberculosis has also increased during the same period, from 33% in 1995 to 56% in 2004. The incidence of FQ-resistant M. tuberculosis is gradually increasing to alarming levels. This may be due to widespread use of this vital group of drugs in the treatment of community-acquired infections. We urge that these broad spectrum antibiotics be used judiciously, and ideally be reserved for treatment of resistant TB in TB-endemic areas.

  18. Connecting HRM and change management: the importance of proactivity and vitality

    NARCIS (Netherlands)

    Tummers, L.G.; Kruyen, P.M.; Vijverberg, D.M.; Voesenek, T.J.

    2015-01-01

    - Purpose – Organizations are continuously under pressure to adapt to changing circumstances. Job proactivity and vitality are important in changing environments. For instance, vital employees can better deal with change because they possess more energy. However, it is still unclear how

  19. Connecting HRM and Change Management: The Importance of Proactivity and Vitality

    NARCIS (Netherlands)

    L.G. Tummers (Lars); P.M. Kruyen; D. Vijverberg (Dominique); T. Voesenek (Tessa)

    2015-01-01

    textabstractPurpose. Organizations are continuously under pressure to adapt to changing circumstances. Job proactivity and vitality are important in changing environments. For instance, vital employees can better deal with change because they possess more energy. However, it is still unclear how

  20. Connecting HRM and Change Management: The Importance of Proactivity and Vitality

    NARCIS (Netherlands)

    Tummers, L.G.; Kruyen, P.M.; Vijverberg, D.; Voesenek, T.

    2015-01-01

    Purpose. Organizations are continuously under pressure to adapt to changing circumstances. Job proactivity and vitality are important in changing environments. For instance, vital employees can better deal with change because they possess more energy. However, it is still unclear how organizations

  1. Optical sensor for measuring American Lobster vitality

    International Nuclear Information System (INIS)

    Tomassetti, Brian R. A.; Vetelino, John F.

    2011-01-01

    The vitality of the American Lobster (Homarus americanus) is correlated to the total hemolymph protein (THP) in lobster hemolymph (blood). The standard technique for determining lobster vitality is to draw blood from a lobster and measure THP with a refractometer. This technique is invasive and endangers the lobster's health since blood must be drawn from the lobster. In the present work an optical sensor is developed to measure a lobster's vitality in vivo. It is comprised of a broadband light source, a monochromator, a fiber optic reflection probe, a spectrometer and a computer. This sensor measures protein concentrations by exciting a lobster with 280 nm and 334 nm wavelength light sources and measuring the corresponding absorbance peaks for THP and the fluorescence peak for hemocyanin (Hc), the majority protein in hemolymph. In this work several lobsters are tested. For each lobster, absorbance and fluorescence peaks are measured using the sensor and compared to protein concentrations measured using a refractometer. It is found that the shell thickness and muscle density, which correspond directly to protein concentration and the molting stage of the lobster have a significant effect on the absorbance and fluorescence measurements. It is also found that within specific molting stages, such as pre-molt and post-molt, protein concentration measured with a refractometer correlates linearly to absorbance and fluorescence measurements with the optical sensor.

  2. Optical Sensor for Measuring American Lobster Vitality

    Science.gov (United States)

    Tomassetti, Brian R. A.; Vetelino, John F.

    2011-06-01

    The vitality of the American Lobster (Homarus americanus) is correlated to the total hemolymph protein (THP) in lobster hemolymph (blood). The standard technique for determining lobster vitality is to draw blood from a lobster and measure THP with a refractometer. This technique is invasive and endangers the lobster's health since blood must be drawn from the lobster. In the present work an optical sensor is developed to measure a lobster's vitality in vivo. It is comprised of a broadband light source, a monochromator, a fiber optic reflection probe, a spectrometer and a computer. This sensor measures protein concentrations by exciting a lobster with 280 nm and 334 nm wavelength light sources and measuring the corresponding absorbance peaks for THP and the fluorescence peak for hemocyanin (Hc), the majority protein in hemolymph. In this work several lobsters are tested. For each lobster, absorbance and fluorescence peaks are measured using the sensor and compared to protein concentrations measured using a refractometer. It is found that the shell thickness and muscle density, which correspond directly to protein concentration and the molting stage of the lobster have a significant effect on the absorbance and fluorescence measurements. It is also found that within specific molting stages, such as pre-molt and post-molt, protein concentration measured with a refractometer correlates linearly to absorbance and fluorescence measurements with the optical sensor.

  3. CDC Vital Signs-African American Health

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the May 2017 CDC Vital Signs report. The life expectancy of African Americans has improved, but it's still an average of four years less than whites. Learn what can be done so all Americans can have the opportunity to pursue a healthy lifestyle.

  4. Renovascular resistance of machine-perfused DCD kidneys is associated with primary nonfunction.

    NARCIS (Netherlands)

    Vries, E.E. de; Hoogland, E.R.; Winkens, B.; Snoeijs, M.G.; Heurn, L.W.E. van

    2011-01-01

    Donation after cardiac death (DCD) has shown to be a valuable extension of the donor pool despite a higher percentage of primary nonfunction (PNF). Limiting the incidence of PNF is of vital importance. Renovascular resistance is believed to predict graft outcome; however the literature is

  5. 33 CFR 157.435 - Vital systems surveys.

    Science.gov (United States)

    2010-07-01

    ...) POLLUTION RULES FOR THE PROTECTION OF THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Interim Measures for Certain Tank Vessels Without Double Hulls Carrying Petroleum Oils § 157.435 Vital...

  6. In vitro fracture resistance of three commercially available zirconia crowns for primary molars.

    Science.gov (United States)

    Townsend, Janice A; Knoell, Patrick; Yu, Qingzhao; Zhang, Jian-Feng; Wang, Yapin; Zhu, Han; Beattie, Sean; Xu, Xiaoming

    2014-01-01

    The purpose of this study was to measure the fracture resistance of primary mandibular first molar zirconia crowns from three different manufacturers-EZ Pedo (EZP), NuSmile (NSZ), and Kinder Krowns (KK)-and compare it with the thickness of the zirconia crowns and the measured fracture resistance of preveneered stainless steel crowns (SSCs). The thickness of 20 zirconia crowns from three manufacturers were measured. The mean force required to fracture the crowns was determined. Preveneered NuSmile (NSW) SSCs were tested as a control. EZP crowns were significantly thicker in three of the six measured locations. The force required to fracture the EZP crown was significantly higher than that required for NSZ and KK. There was a positive correlation between fracture resistance and crown thickness in the mesial, distal, mesioocclusal, and distoocclusal dimensions. None of the zirconia crowns proved to be as resistant to fracture as the preveneered SSCs. Statistically significant differences were found among the forces required to fracture zirconia crowns by three different manufacturers. The increase in force correlated with crown thickness. The forces required to fracture the preveneered stainless steel crowns were greater than the forces required to fracture all manufacturers' zirconia crowns.

  7. Vital Signs-Preventing Teen Pregnancy

    Centers for Disease Control (CDC) Podcasts

    2015-04-07

    This podcast is based on the April 2015 CDC Vital Signs report. Teen births in the U.S. have declined, but still, more than 273,000 infants were born to teens ages 15 to 19 in 2013. Learn about the most effective types of birth control.  Created: 4/7/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/7/2015.

  8. CDC Vital Signs-Heart Age

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the September 2015 CDC Vital Signs report. Your heart age is the age of your heart and blood vessels as a result of your risk factors for heart attack and stroke. If you smoke or have high blood pressure, your heart age will be much higher than your actual age. Learn what you can do to lower your heart age and keep it low.

  9. CDC Vital Signs-Hispanic Health

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the May 2015 CDC Vital Signs report. About one in six people living in the U.S. are Hispanic. The two leading causes of death in this group are heart disease and cancer, accounting for two out of five deaths. Unfortunately, many Hispanics face considerable barriers to getting high quality health care, including language and low income. Learn what can be done to reduce the barriers.

  10. The role of physical activity in pre-service teachers’ subjective vitality

    Directory of Open Access Journals (Sweden)

    Abdullah Bora Özkara

    2017-06-01

    Full Text Available Background: In the present study, subjective vitality considered to be one of the contributions provided by participation in physical activity is examined on a sample of pre-service teachers. When teachers who are important part of education system are healthy and fit, it will help to build future generations. Materials: The research was conducted in the city of Trabzon, located in the northeastern region of Turkey. The sample of the study is composed of 328 last grade pre-service teachers (133 women, 195 men, age: 23.14 ± 2.62 studying at Karadeniz Technical University in the academic year of 2015-2016. Data was collected through Childhood and Adolescence Physical Activity Levels Questionnaire, Subjective Vitality Scale, and a personal information form asking for information about gender, doing sports as a certified sportsman/woman and department. Results: The research results yielded a significant difference between subjective vitality levels of those who do sports as a certified sportsman/woman and those who do not, and between pre-service teachers of physical education and those of other departments (p<0,01. There was also a positive and low-level significant relationship between subjective vitality and physical activity experiences of pre-service teachers (r= .23; p<0.01. However, subjective vitality did not differ significantly by gender. Conclusions: The research results seem to support other studies that reveal social and psychological contributions provided by participation in physical activity. Therefore, participation in physical activity seems to have positive effects on the subjective vitality of pre-service teachers.

  11. Role of the plant cell wall in gravity resistance.

    Science.gov (United States)

    Hoson, Takayuki; Wakabayashi, Kazuyuki

    2015-04-01

    Gravity resistance, mechanical resistance to the gravitational force, is a principal graviresponse in plants, comparable to gravitropism. The cell wall is responsible for the final step of gravity resistance. The gravity signal increases the rigidity of the cell wall via the accumulation of its constituents, polymerization of certain matrix polysaccharides due to the suppression of breakdown, stimulation of cross-link formation, and modifications to the wall environment, in a wide range of situations from microgravity in space to hypergravity. Plants thus develop a tough body to resist the gravitational force via an increase in cell wall rigidity and the modification of growth anisotropy. The development of gravity resistance mechanisms has played an important role in the acquisition of responses to various mechanical stresses and the evolution of land plants. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. CDC Vital Signs: Preventing Repeat Teen Births

    Science.gov (United States)

    ... control after they have given birth. Although teen birth rates have been falling for the last two decades, ... effective forms of birth control. SOURCE: National Vital Statistics System, teens, ages 15–19, 2010 Larger image ...

  13. CDC Vital Signs-Hospital Actions Affect Breastfeeding

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the October 2015 CDC Vital Signs report. Hospitals can implement the Ten Steps to Successful Breastfeeding to be designated as "Baby-Friendly" and support more moms in a decision to breastfeed.

  14. Algorithm To Ensure And Enforce Brute-Force Attack-Resilient Password In Routers

    OpenAIRE

    Mohammed Farik; ABM Shawkat Ali

    2015-01-01

    Abstract Issues of weak login passwords arising from default passwords in wired and wireless routers has been a concern for more than a decade. In this research we develop and test an algorithm to ensure and enforce passwords in routers that are resistant to brute-force attack. A comparative analysis is performed to show the improved strengths of passwords derived via this algorithm. Implementation of this algorithm in routers will ensure setup of brute-force attack resistant passwords.

  15. ED Triage Process Improvement: Timely Vital Signs for Less Acute Patients.

    Science.gov (United States)

    Falconer, Stella S; Karuppan, Corinne M; Kiehne, Emily; Rama, Shravan

    2018-06-13

    Vital signs can result in an upgrade of patients' Emergency Severity Index (ESI) levels. It is therefore preferable to obtain vital signs early in the triage process, particularly for ESI level 3 patients. Emergency departments have an opportunity to redesign triage processes to meet required protocols while enhancing the quality and experience of care. We performed process analyses to redesign the door-to-vital signs process. We also developed spaghetti diagrams to reconfigure the patient arrival area. The door-to-vital signs time was reduced from 43.1 minutes to 6.44 minutes. Both patients and triage staff seemed more satisfied with the new process. The patient arrival area was less congested and more welcoming. Performing activities in parallel reduces flow time with no additional resources. Staff involvement in process planning, redesign, and control ensures engagement and early buy-in. One should anticipate how changes to one process might affect other processes. Copyright © 2018. Published by Elsevier Inc.

  16. Application of thermo-electromotive force and electric resistance measuring methods to researching phase transformations in Zr1Nb alloy

    International Nuclear Information System (INIS)

    Klimenko, S.P.; Gritsina, V.M.; Petel'guzov, I.A.; Chernyaeva, T.P.

    2007-01-01

    The paper determines the applicability areas of different methods for the study of structural phase transformations in a Zr+1Nb alloy, which is extensively used in reactor construction; production and fabrication of products from Zr+1Nb is currently developed in Ukraine. Electromotive force and electric resistance were measured to study structural phase transformations of Zr+1Nb fuel rod tubes based on calciumthermal zirconium (Zr1Nb). It was established that changes in electric resistance clearly show the beginning of a massive α → β transition at ∼ 750 degree C and the end of α → β transition at ∼ 950 degree C, whereas measurement of thermo-e.m.f. in the samples subjected to successive 3-hour step annealing in the temperature range from 300 to 700 degree C allows the temperature of monotectoid transformation to be found. For sample Zr1Nb batches the temperature of monotectoid transformation is (620±7) degree C. The measurement results are consistent with the similar studies carried out on Zr+1Nb fuel rod tubes based on electrolytic zirconium (E110), for which the temperature of monotectoid transformation is equal to ∼ 610 degree C

  17. Vital Signs – Childhood Obesity

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the August 2013 CDC Vital Signs report. The rate of obesity among low-income preschoolers has declined, but one in eight is still obese. This program briefly discusses what can be done.

  18. Knowledge, access and utilization of bed-nets among stable and seasonal migrants in an artemisinin resistance containment area of Myanmar

    OpenAIRE

    Phyo Than, Wint; Oo, Tin; Wai, Khin Thet; Thi, Aung; Owiti, Philip; Kumar, Binay; Deepak Shewade, Hemant; Zachariah, Rony

    2017-01-01

    Background Myanmar lies in the Greater Mekong sub-region of South-East Asia faced with the challenge of emerging resistance to artemisinin combination therapies (ACT). Migrant populations are more likely than others to spread ACT resistance. A vital intervention to reduce malaria transmission, resistance spread and eliminate malaria is the use of bed nets. Among seasonal and stable migrants in an artemisinin resistance containment region of Myanmar, we compared a) their household characterist...

  19. CDC Vital Signs-Preventing Melanoma

    Centers for Disease Control (CDC) Podcasts

    2015-06-02

    This podcast is based on the June 2015 CDC Vital Signs report. Skin cancer is the most common form of cancer in the U.S. In 2011, there were more than 65,000 cases of melanoma, the most deadly form of skin cancer. Learn how everyone can help prevent skin cancer.  Created: 6/2/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 6/2/2015.

  20. Vital Signs - Child Passenger Safety

    Centers for Disease Control (CDC) Podcasts

    2014-02-04

    This podcast is based on the February 2014 CDC Vital Signs report. Over the past 10 years, more than 9,000 children 12 and under died in motor vehicle crashes, and a third who died in 2011 weren't buckled up. Buckling up is the best way to reduce injuries and save lives.  Created: 2/4/2014 by National Center for Injury Prevention and Control (NCIPC).   Date Released: 2/4/2014.

  1. Geographic variation in Chinese children' forced vital capacity and its association with long-term exposure to local PM10: a national cross-sectional study.

    Science.gov (United States)

    Wang, Hai-Jun; Li, Qin; Guo, Yuming; Song, Jie-Yun; Wang, Zhiqiang; Ma, Jun

    2017-10-01

    The purpose of this study was to estimate the association between Chinese children's forced vital capacity (FVC) and particulate matter with aerodynamic diameter ≤10 μm (PM 10 ). The FVC data of 71,763 children aged 7 to 18 was collected from 2010 Chinese National Survey on Students' Construction and Health (CNSSCH). The local annual average concentration of PM 10 , relative humidity, ambient temperature, and other air pollutant data of 30 cities was collected from China Meteorological Administration and Ministry of Environment Protection of China. Then, we used generalized additive model (GAM) to estimate the association between children's FVC and PM 10 . The obvious geographic variation in FVC was found in children of 30 Chinese cities ranging from 1647 ml in Xining to 2571 ml in Beijing. The annual average concentration of PM 10 was also different, ranging from 40 μg/m 3 in Haikou to 155 μg/m 3 in Lanzhou. After adjusted individual characteristics, socioeconomic conditions, ambient temperature, relative humidity, and other air pollutants (e.g., NO 2 and SO 2 ) in the generalized additive model, we found that the increase of PM 10 was associated with decrease of FVC in Chinese children. A 10-μg/m 3 increase of PM 10 was associated with 1.33-ml decrease in FVC (95% confidence interval: -2.18 to -0.47). We also found a larger effect estimate of PM 10 on FVC in boys than that in girls. Consistent associations were found in both physically inactive and active children. The increase of PM 10 was associated with decrease of children's FVC. We should develop proper public health policy to protect children's respiratory health during growth and development in polluted areas.

  2. Energy brands lack vitality

    International Nuclear Information System (INIS)

    Godri, S.; Wilders, E.

    2004-01-01

    The three Dutch energy companies (Nuon, Essent and Eneco Energie) have relatively little brand strength. The brands are not perceived to be sufficiently different from one another and are not valued by consumers. With liberalisation imminent, this is hardly a strong starting point. How can you win over consumers if it is not clear what is on offer? In the business market, decision-makers are better placed to distinguish between brands. However, the brands lack vitality in this sector of the market too. The only consolation is that the situation is by no means exclusive to the Netherlands [nl

  3. Force production during squats performed with a rotational resistance device under stable versus unstable conditions.

    Science.gov (United States)

    Moras, Gerard; Vázquez-Guerrero, Jairo

    2015-11-01

    [Purpose] Force production during a squat action on a rotational resistance device (RRD) under stable and unstable conditions. [Subjects and Methods] Twenty-one healthy males were asked to perform six sets of six repetitions of squats on an RRD on either stable or unstable surfaces. The stable and unstable sets were performed on different days. Muscular outputs were obtained from a linear encoder and a strain gauge fixed to a vest. [Results] Overall, the results showed no significant differences for any of the dependent variables across exercise modes. Forcemean outputs were higher in the concentric phase than in the eccentric phase for each condition, but there were no differences in velocity, time or displacement. The forcepeak was similar in the eccentric and concentric phases of movement under both stable and unstable conditions. There were no significant differences in forcemean between sets per condition or between conditions. [Conclusion] These results suggest that performing squats with a RRD achieves similar forcemean and forcepeak under stable and unstable conditions. The forcepeak produced is also similar in concentric and eccentric phases.

  4. VitalQPlus: a potential screening tool for early diagnosis of COPD

    Directory of Open Access Journals (Sweden)

    Sui CF

    2015-08-01

    Full Text Available Chee Fai Sui,1 Long Chiau Ming,2,3 Chin Fen Neoh,2,4 Baharudin Ibrahim1 1School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, 2Faculty of Pharmacy, Universiti Teknologi MARA, 3Brain Degeneration and Therapeutics Group, 4Collaborative Drug Discovery Research (CDDR Group, Pharmaceutical and Life Sciences (PLS Community of Research (CoRe, UiTM, Selangor, Malaysia Background: This study utilized a validated combination of a COPD Population Screener (COPD-PS questionnaire and a handheld spirometric device as a screening tool for patients at high risk of COPD, such as smokers. The study aimed to investigate and pilot the feasibility and application of this combined assessment, which we termed the “VitalQPlus”, as a screening tool for the early detection of COPD, especially in primary care settings. Methods: This was a cross-sectional study screening potentially undiagnosed COPD patients using a validated five-item COPD-PS questionnaire together with a handheld spirometric device. Patients were recruited from selected Malaysian government primary care health centers. Results: Of the total of 83 final participants, only 24.1% (20/83 were recruited from Perak and Penang (peninsular Malaysia compared to 75.9% (63/83 from Sabah (Borneo region. Our dual assessment approach identified 8.4% of the surveyed patients as having potentially undiagnosed COPD. When only the Vitalograph COPD-6 screening tool was used, 15.8% of patients were detected with a forced expiratory volume in 1 second/forced expiratory volume in 6 seconds (FEV1/FEV6 ratio at <0.75, while 35.9% of patients were detected with the COPD-PS questionnaire. These findings suggested that this dual assessment approach has a greater chance of identifying potentially undiagnosed COPD patients compared to the Vitalograph COPD-6 or COPD-PS questionnaire when used alone. Our findings show that patients with more symptoms (scores of ≥5 yielded twice the percentage of outcomes of FEV1

  5. Vital Signs-Motor Vehicle Crash Injuries

    Centers for Disease Control (CDC) Podcasts

    2014-10-07

    This podcast is based on the October 2014 CDC Vital Signs report. Motor vehicle crashes are costly and preventable. Learn what can be done to help prevent motor vehicle injuries.  Created: 10/7/2014 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 10/7/2014.

  6. Dynamic behavior of tuning fork shear-force structures in a SNOM system

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Fengli [Department of Engineering Mechanics, AML, CNMM, Tsinghua University, Beijing 100084 (China); Li, Xide, E-mail: lixide@tsinghua.edu.cn [Department of Engineering Mechanics, AML, CNMM, Tsinghua University, Beijing 100084 (China); Wang, Jia [State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instruments, Tsinghua University, Beijing 100084 (China); Fu, Yu [Temasek Laboratories, Nanyang Technological University, 50 Nanyang Drive, 637553 (Singapore)

    2014-07-01

    Piezoelectric tuning fork shear-force structures are widely used as a distance control unit in a scanning near-field optical microscopy. However, the complex dynamic behavior among the micro-tuning forks (TFs), optical fiber probes, and the probe–surface interactions is still a crucial issue to achieve high-resolution imaging or near-field interaction inspections. Based on nonlinear beam tension-bending vibration theory, vibration equations in both longitudinal and lateral directions have been established when the TF structure and the optical fiber are treated as deformable structures. The relationship of the probe–surface interaction induced by Van der Waals force has been analyzed and the corresponding numerical results used to describe the vibrational behavior of the probe approaching the sample surface are obtained. Meanwhile, the viscous resistance of the liquid film on the sample surface has also been investigated using linear beam-bending vibration theory. Experiments testing the interaction between the probe and the water film on a single crystal silicon wafer have been carried out and the viscous resistance of the water film was estimated using the established equations. Finally, to use the TF-probe structure as a force sensor, the relation between the dynamic response of the TF-probe system and an external force on the probe tip was obtained. - Highlights: • Nonlinear vibration equation is established for a deformable tuning fork probe assembly. • Probe–sample interactions induced by Van der Waals force and viscous resistance are investigated. • The viscous resistance between the probe and the water film is estimated using testing results.

  7. Vital coalitions, vital regions; cooperation in sustainable, regional development

    NARCIS (Netherlands)

    Horlings, L.G.

    2010-01-01

    Many rural regions in Europe are undergoing a dynamic transition, driven by forces of urbanisation and agricultural development, new patterns of production and consumption, and new societal demands. However, while the historical rural-urban divide is eroding, rural landscapes are becoming more

  8. CDC Vital Signs- Proteja a los pacientes contra la resistencia a los antibióticos (Protect Patients from Antibiotic Resistance)

    Centers for Disease Control (CDC) Podcasts

    Este podcast se basa en la edición de marzo del 2016 del informe Signos Vitales de los CDC. Mientras reciben atención médica en un centro hospitalario, los pacientes pueden contraer infecciones graves asociadas a la atención médica. Infórmese sobre cómo prevenir las infecciones asociadas a la atención médica.

  9. An Assessment of LAC's Vital Statistics System : The Foundation of Maternal and Infant Mortality Monitoring

    OpenAIRE

    Danel, Isabella; Bortman, Marcelo

    2008-01-01

    Vital records, the registration of births, deaths, marriages and divorces, and the vital statistics derived from these records serve two important purposes. Firstly, vital records are legal documents, but the focus of this review, is the role of vital records to create demographic and epidemiological statistics that are used in monitoring trends and developing health policies and programs....

  10. Current-induced forces: a new mechanism to induce negative differential resistance and current-switching effect in molecular junctions

    Science.gov (United States)

    Gu, Lei; Fu, Hua-Hua

    2015-12-01

    Current-induced forces can excite molecules, polymers and other low-dimensional materials, which in turn leads to an effective gate voltage through Holstein interaction. Here, by taking a short asymmetric DNA junction as an example, and using the Langevin approach, we find that when suppression of charge transport by the effective gate voltage surpasses the current increase from an elevated voltage bias, the current-voltage (I-V) curves display strong negative differential resistance (NDR) and perfect current-switching characteristics. The asymmetric DNA chain differs in mechanical stability under inverse voltages and the I-V curve is asymmetric about inverse biases, which can be used to understand recent transport experiments on DNA chains, and meanwhile provides a new strategy to realize NDR in molecular junctions and other low-dimensional quantum systems.

  11. Current-induced forces: a new mechanism to induce negative differential resistance and current-switching effect in molecular junctions

    International Nuclear Information System (INIS)

    Gu, Lei; Fu, Hua-Hua

    2015-01-01

    Current-induced forces can excite molecules, polymers and other low-dimensional materials, which in turn leads to an effective gate voltage through Holstein interaction. Here, by taking a short asymmetric DNA junction as an example, and using the Langevin approach, we find that when suppression of charge transport by the effective gate voltage surpasses the current increase from an elevated voltage bias, the current-voltage (I–V) curves display strong negative differential resistance (NDR) and perfect current-switching characteristics. The asymmetric DNA chain differs in mechanical stability under inverse voltages and the I–V curve is asymmetric about inverse biases, which can be used to understand recent transport experiments on DNA chains, and meanwhile provides a new strategy to realize NDR in molecular junctions and other low-dimensional quantum systems. (paper)

  12. Advanced remotely maintainable force-reflecting servomanipulator concept

    International Nuclear Information System (INIS)

    Kuban, D.P.; Martin, H.L.

    1984-01-01

    A remotely maintainable force-reflecting servomanipulator concept is being developed at the Oak Ridge National Laboratory as part of the Consolidated Fuel Reprocessing Program. This new manipulator addresses requirements of advanced nuclear fuel reprocessing with emphasis on force reflection, remote maintainability, reliability, radiation tolerance, and corrosion resistance. The advanced servomanipulator is uniquely subdivided into remotely replaceable modules which will permit in situ manipulator repair by spare module replacement. Manipulator modularization and increased reliability are accomplished through a force transmission system that uses gears and torque tubes. Digital control algorithms and mechanical precision are used to offset the increased backlash, friction, and inertia resulting from the gear drives. This results in the first remotely maintainable force-reflecting servomanipulator in the world. 10 references, 4 figures, 1 table

  13. Algorithm To Ensure And Enforce Brute-Force Attack-Resilient Password In Routers

    Directory of Open Access Journals (Sweden)

    Mohammed Farik

    2015-08-01

    Full Text Available Abstract Issues of weak login passwords arising from default passwords in wired and wireless routers has been a concern for more than a decade. In this research we develop and test an algorithm to ensure and enforce passwords in routers that are resistant to brute-force attack. A comparative analysis is performed to show the improved strengths of passwords derived via this algorithm. Implementation of this algorithm in routers will ensure setup of brute-force attack resistant passwords.

  14. Vital Signs-Cervical Cancer is Preventable!

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the November 2014 CDC Vital Signs report. Every visit to a doctor or nurse is an opportunity to prevent cervical cancer. Women can get a Pap test and HPV test to help prevent cervical cancer and adolescent boys and girls can get the HPV vaccination series to help prevent cervical and other cancers.

  15. Transgenic approaches for development of disease resistance in banana

    International Nuclear Information System (INIS)

    Shekhawat, Upendra K.S.; Ghag, Siddhesh B.; Ganapathi, Thumballi R.

    2014-01-01

    Banana (Musa spp.) is an important food and cash crop worldwide. Diseases and pests pose the most serious constraint to banana cultivation. Among the diseases, Fusarium wilt and Banana Bunchy Top Virus (BBTV) are the most important economically. We have explored different transgenic approaches for development of efficient resistance in banana against these two diseases. For countering Fusarium wilt, we have over expressed Petunia floral defensins using a strong constitutive promoter in transgenic banana plants. We have also tested a host induced gene silencing strategy targeting two vital fungal genes to obtain Fusarium resistant banana plants. For development of BBTV resistant banana plants also, we have used a host-induced gene silencing approach utilizing the full and partial coding sequence of the viral replication initiation protein. Successful bioassays performed in controlled greenhouse conditions have shown the efficacy of using these strategies to develop disease resistant banana plants. (author)

  16. Radio and the Art of Resistance: A Public Pedagogy of the Airwaves

    Science.gov (United States)

    Darder, Antonia

    2011-01-01

    The politics of the airwaves should be of vital concern to critical democracy, given the expanding realm of neoliberalism and its deeply homogenizing impact on social, political and economic relations everywhere. In light of the privatizing forces that control the media today, the article considers the manner in which community radio can provide…

  17. Mapping the resistance-associated mobilome of a carbapenem-resistant Klebsiella pneumoniae strain reveals insights into factors shaping these regions and facilitates generation of a 'resistance-disarmed' model organism.

    Science.gov (United States)

    Bi, Dexi; Jiang, Xiaofei; Sheng, Zi-Ke; Ngmenterebo, David; Tai, Cui; Wang, Minggui; Deng, Zixin; Rajakumar, Kumar; Ou, Hong-Yu

    2015-10-01

    This study aims to investigate the landscape of the mobile genome, with a focus on antibiotic resistance-associated factors in carbapenem-resistant Klebsiella pneumoniae. The mobile genome of the completely sequenced K. pneumoniae HS11286 strain (an ST11, carbapenem-resistant, near-pan-resistant, clinical isolate) was annotated in fine detail. The identified mobile genetic elements were mapped to the genetic contexts of resistance genes. The blaKPC-2 gene and a 26 kb region containing 12 clustered antibiotic resistance genes and one biocide resistance gene were deleted, and the MICs were determined again to ensure that antibiotic resistance had been lost. HS11286 contains six plasmids, 49 ISs, nine transposons, two separate In2-related integron remnants, two integrative and conjugative elements (ICEs) and seven prophages. Sixteen plasmid-borne resistance genes were identified, 14 of which were found to be directly associated with Tn1721-, Tn3-, Tn5393-, In2-, ISCR2- and ISCR3-derived elements. IS26 appears to have actively moulded several of these genetic regions. The deletion of blaKPC-2, followed by the deletion of a 26 kb region containing 12 clustered antibiotic resistance genes, progressively decreased the spectrum and level of resistance exhibited by the resultant mutant strains. This study has reiterated the role of plasmids as bearers of the vast majority of resistance genes in this species and has provided valuable insights into the vital role played by ISs, transposons and integrons in shaping the resistance-coding regions in this important strain. The 'resistance-disarmed' K. pneumoniae ST11 strain generated in this study will offer a more benign and readily genetically modifiable model organism for future extensive functional studies. © The Author 2015. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  18. CDC Vital Signs-Safer Food Saves Lives

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the November 2015 CDC Vital Signs report. Contaminated food sent to several states can cause multistate outbreaks of foodborne illness and make a lot of people seriously ill. Learn what can be done to prevent and stop outbreaks.

  19. Effects of Sled Towing on Peak Force, the Rate of Force Development and Sprint Performance During the Acceleration Phase

    Directory of Open Access Journals (Sweden)

    Martínez-Valencia María Asunción

    2015-06-01

    Full Text Available Resisted sprint training is believed to increase strength specific to sprinting. Therefore, the knowledge of force output in these tasks is essential. The aim of this study was to analyze the effect of sled towing (10%, 15% and 20% of body mass (Bm on sprint performance and force production during the acceleration phase. Twenty-three young experienced sprinters (17 men and 6 women; men = 17.9 ± 3.3 years, 1.79 ± 0.06 m and 69.4 ± 6.1 kg; women = 17.2 ± 1.7 years, 1.65 ± 0.04 m and 56.6 ± 2.3 kg performed four 30 m sprints from a crouch start. Sprint times in 20 and 30 m sprint, peak force (Fpeak, a peak rate of force development (RFDpeak and time to RFD (TRFD in first step were recorded. Repeated-measures ANOVA showed significant increases (p ≤ 0.001 in sprint times (20 and 30 m sprint for each resisted condition as compared to the unloaded condition. The RFDpeak increased significantly when a load increased (3129.4 ± 894.6 N·s−1, p ≤ 0.05 and 3892.4 ± 1377.9 N·s−1, p ≤ 0.01. Otherwise, no significant increases were found in Fpeak and TRFD. The RFD determines the force that can be generated in the early phase of muscle contraction, and it has been considered a factor that influences performance of force-velocity tasks. The use of a load up to 20% Bm might provide a training stimulus in young sprinters to improve the RFDpeak during the sprint start, and thus, early acceleration.

  20. Psychological Operations: Air Force Doctrine Document 2-5.5

    National Research Council Canada - National Science Library

    1997-01-01

    ..., decision making processes, and behavior. Examples of PSYOP include: promises, threats of force or retaliation, conditions of surrender safe passage for deserters, or support to resistance groups...

  1. «L'angoixa vital» i la narrativa valenciana de postguerra

    Directory of Open Access Journals (Sweden)

    Assumpció Bernal

    2015-11-01

    Full Text Available The purpose of the paper is to analyse the post-war Valencian narrative and the vital agony which is present in almost all the published short stories, especially after Joan Fuster's Recull de contes valencians published in 1958. It also analyses the authors' short stories, the readings, influences and the importance of existencialism and vital pessimism.

  2. «L'angoixa vital» i la narrativa valenciana de postguerra

    OpenAIRE

    Assumpció Bernal

    2015-01-01

    The purpose of the paper is to analyse the post-war Valencian narrative and the vital agony which is present in almost all the published short stories, especially after Joan Fuster's Recull de contes valencians published in 1958. It also analyses the authors' short stories, the readings, influences and the importance of existencialism and vital pessimism.

  3. Insights into the concept of vitality: associations with participation and societal costs.

    NARCIS (Netherlands)

    Steenbergen, E.; van Dongen, J.M.; Wendel-Vos, G.C.; Hildebrandt, V.H.; Strijk, J.E.

    2016-01-01

    BACKGROUND: In healthcare, the focus is currently shifting from someone's disabilities to someone's abilities, which is also evident from the increasing focus on vitality. Vitality (here defined as energy, motivation and resilience) is an often used concept, which also aims at someone's

  4. Development anomaly and non-vitality: Two case reports

    Directory of Open Access Journals (Sweden)

    Sivakumar Kailasam

    2012-01-01

    Full Text Available Anatomic aberrations are seen in human dentition. The maxillary incisor region of the permanent dentition where these anatomical aberrations are commonly seen is considered an area of embryonic hazard. Aberrations affecting the internal and external morphology can at times be the cause of complex pathological conditions involving the pulpal and periodontal tissues and can pose a challenge to the clinician for the diagnosis and clinical management. Detecting and treating the anomalies at an early phase is essential as it poses a threat for the loss of vitality of the concerned teeth. The aim of this paper is to highlight the fact two different developmental anomalies of maxillary incisors, namely palatoradicular groove and Turner′s hypoplasia, led to the loss of vitality of the same.

  5. Note: A rigid piezo motor with large output force and an effective method to reduce sliding friction force.

    Science.gov (United States)

    Guo, Ying; Hou, Yubin; Lu, Qingyou

    2014-05-01

    We present a completely practical TunaDrive piezo motor. It consists of a central piezo stack sandwiched by two arm piezo stacks and two leg piezo stacks, respectively, which is then sandwiched and spring-clamped by a pair of parallel polished sapphire rods. It works by alternatively fast expanding and contracting the arm/leg stacks while slowly expanding/contracting the central stack simultaneously. The key point is that sufficiently fast expanding and contracting a limb stack can make its two sliding friction forces well cancel, resulting in the total sliding friction force is piezo motor's high compactness, precision, and output force make it perfect in building a high-quality harsh-condition (vibration resistant) atomic resolution scanning probe microscope.

  6. Leveraging intellectual capital through Lewin's Force Field Analysis: The case of software development companies

    Directory of Open Access Journals (Sweden)

    Alexandru Capatina

    2017-09-01

    Full Text Available This article presents an original conceptual framework for the strategic management of intellectual capital assets in software development companies. The framework is based on Lewin's Force Field Analysis. The framework makes it possible to assess software company managers’ opinions regarding the way driving and restraining forces affect the pillars of intellectual capital. The capacity to adapt to change is vital for companies in knowledge-intensive industries. Accordingly, this study examined a sample of 74 Romanian software development companies. The aim was to help companies benefit from managing the driving and restraining forces acting upon the pillars of intellectual capital (human, structural, and relational. The effects of the driving forces, quantified by PathMaker software's Force Field Tool, were observed to be greater than the restraining forces for each pillar of intellectual capital. This paper contributes by showing the explanatory power of this framework. The framework thus offers a tool that helps managers drive change in their organizations through effective intellectual capital management. Furthermore, this article describes how to encourage the implementation of changes that create value for software development companies.

  7. Insights into the concept of vitality: associations with participation and societal costs

    NARCIS (Netherlands)

    Steenbergen, E. van; Dongen, J.M. van; Wendel-Vos, G.C.W.; Hildebrandt, V.H.; Strijk, J.E.

    2016-01-01

    Background: In healthcare, the focus is currently shifting from someone’s disabilities to someone’s abilities, which is also evident from the increasing focus on vitality. Vitality (here defined as energy, motivation and resilience) is an often used concept, which also aims at someone’s

  8. La teoria del ciclo vitale del risparmio di Modigliani cinquant’anni dopo

    Directory of Open Access Journals (Sweden)

    Mauro Baranzini

    2005-06-01

    Full Text Available Nei primi anni ’50 Franco Modigliani, insieme a Richard Brumberg e ad Albert Ando, formulò lateoria del ciclo vitale del consumo e del risparmio, che ha riscosso un enorme e indiscussosuccesso per almeno tre decenni. Tuttavia, a partire dai primi anni ’80 la teoria del ciclo vitale èstata criticata in modo sempre più serrato, per almeno quattro ragioni. La prima consistenell’esistenza di una significativa trasmissione intergenerazionale della ricchezza, da ricondurre acause esogene al modello del ciclo vitale. La seconda ragione è rappresentata dalla crescenteevidenza che i ricchi continuano a risparmiare in misura maggiore rispetto ai meno fortunati,come, in effetti, Keynes sosteneva. Il terzo motivo è che vi sono prove sempre più evidenti,almeno nell’Europa occidentale e in Giappone, che le famiglie giovani, durante i venti e i trentaanni di età, risparmiano una quota positiva e crescente del proprio reddito, e ciò si pone indeciso contrasto con la versione originaria della teoria del ciclo vitale. Infine, numerosi lavoriempirici hanno rilevato che i pensionati accantonano una parte elevata del proprio reddito. Ciòimpone un serio ripensamento dell’approccio della teoria del ciclo vitale, che interessa sia l’analisieconomica sia la politica economica.

  9. Vital Signs-Preventing Prescription Drug Overdose

    Centers for Disease Control (CDC) Podcasts

    2014-07-01

    This podcast is based on the July 2014 CDC Vital Signs report. Every day, 46 people in the U.S. die from an overdose of prescription opioid painkillers. Learn what can be done to make painkiller prescribing safer and help prevent overdoses.  Created: 7/1/2014 by National Center for Immunization and Respiratory Diseases (NCIRD).   Date Released: 7/1/2014.

  10. 3D finite element modelling of force transmission and particle fracture of sand

    Energy Technology Data Exchange (ETDEWEB)

    Imseeh, Wadi H.; Alshibli, Khalid A. (Tennessee-K)

    2018-02-01

    Global compressive loading of granular media causes rearrangements of particles into a denser configuration. Under 1D compression, researchers observed that particles initially translate and rotate which lead to more contacts between particles and the development of force chains to resist applied loads. Particles within force chains resist most of the applied loads while neighbor particles provide lateral support to prevent particles within force chains from buckling. Several experimental and numerical models have been proposed in the literature to characterize force chains within granular materials. This paper presents a 3D finite element (FE) model that simulates 1D compression experiment on F-75 Ottawa sand. The FE mesh of particles closely matched 3D physical shape of sand particles that were acquired using 3D synchrotron micro-computed tomography (SMT) technique. The paper presents a quantitative assessment of the model, in which evolution of force chains, fracture modes, and stress-strain relationships showed an excellent agreement with experimental measurements reported by Cil et al. Alshibli (2017).

  11. Vital Signs-Preventing Pregnancy in Younger Teens

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the April 2014 CDC Vital Signs report. Births to teens are declining, still, in 2012, more than 86,000 teens ages 15 to 17 gave birth. This program discusses what health care providers, parents, and teens can do to help prevent teen pregnancy.

  12. Localization of the phantom force induced by the tunneling current

    Science.gov (United States)

    Wutscher, Thorsten; Weymouth, Alfred J.; Giessibl, Franz J.

    2012-05-01

    The phantom force is an apparently repulsive force, which can dominate the atomic contrast of an AFM image when a tunneling current is present. We described this effect with a simple resistive model, in which the tunneling current causes a voltage drop at the sample area underneath the probe tip. Because tunneling is a highly local process, the areal current density is quite high, which leads to an appreciable local voltage drop that in turn changes the electrostatic attraction between tip and sample. However, Si(111)-7×7 has a metallic surface state and it might be proposed that electrons should instead propagate along the surface state, as through a thin metal film on a semiconducting surface, before propagating into the bulk. In this paper, we first measure the phantom force on a sample that displays a metallic surface state [here, Si(111)-7×7] using tips with various radii. If the metallic surface state would lead to a constant electrostatic potential on the surface, we would expect a direct dependence of the phantom force with tip radius. In a second set of experiments, we study H/Si(100), a surface that does not have a metallic surface state. We conclude that a metallic surface state does not suppress the phantom force, but that the local resistance Rs has a strong effect on the magnitude of the phantom force.

  13. Monitoring of Vital Signs with Flexible and Wearable Medical Devices.

    Science.gov (United States)

    Khan, Yasser; Ostfeld, Aminy E; Lochner, Claire M; Pierre, Adrien; Arias, Ana C

    2016-06-01

    Advances in wireless technologies, low-power electronics, the internet of things, and in the domain of connected health are driving innovations in wearable medical devices at a tremendous pace. Wearable sensor systems composed of flexible and stretchable materials have the potential to better interface to the human skin, whereas silicon-based electronics are extremely efficient in sensor data processing and transmission. Therefore, flexible and stretchable sensors combined with low-power silicon-based electronics are a viable and efficient approach for medical monitoring. Flexible medical devices designed for monitoring human vital signs, such as body temperature, heart rate, respiration rate, blood pressure, pulse oxygenation, and blood glucose have applications in both fitness monitoring and medical diagnostics. As a review of the latest development in flexible and wearable human vitals sensors, the essential components required for vitals sensors are outlined and discussed here, including the reported sensor systems, sensing mechanisms, sensor fabrication, power, and data processing requirements. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Bacterial resistance and impetigo treatment trends: a review.

    Science.gov (United States)

    Bangert, Scott; Levy, Moise; Hebert, Adelaide A

    2012-01-01

    Impetigo is a common cutaneous infection that is especially prevalent in children. The prevalence of colonization and infection with resistant strains is continually increasing, forcing clinicians to reevaluate treatment strategies. Newer topical agents are effective in treating infections with resistant strains and may help minimize resistance and adverse effects from systemic agents. Use of topical disinfectants to decrease colonization is an important adjunctive measure. Physicians should be aware of local resistance patterns in impetigo to help guide therapy. © 2012 Wiley Periodicals, Inc.

  15. Early and Late Rate of Force Development

    DEFF Research Database (Denmark)

    Andersen, Lars L; Andersen, Jesper L; Zebis, Mette K

    2010-01-01

    The objective of this study is to investigate the potentially opposing influence of qualitative and quantitative muscular adaptations in response to high-intensity resistance training on contractile rate of force development (RFD) in the early (<100 ms) and later phases (>200 ms) of rising muscle...

  16. CDC Vital Signs-Heart Age

    Centers for Disease Control (CDC) Podcasts

    2015-09-01

    This podcast is based on the September 2015 CDC Vital Signs report. Your heart age is the age of your heart and blood vessels as a result of your risk factors for heart attack and stroke. If you smoke or have high blood pressure, your heart age will be much higher than your actual age. Learn what you can do to lower your heart age and keep it low.  Created: 9/1/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 9/1/2015.

  17. CDC Vital Signs-Hispanic Health

    Centers for Disease Control (CDC) Podcasts

    2015-05-05

    This podcast is based on the May 2015 CDC Vital Signs report. About one in six people living in the U.S. are Hispanic. The two leading causes of death in this group are heart disease and cancer, accounting for two out of five deaths. Unfortunately, many Hispanics face considerable barriers to getting high quality health care, including language and low income. Learn what can be done to reduce the barriers.  Created: 5/5/2015 by Office of Minority Health & Health Equity (OMHHE).   Date Released: 5/5/2015.

  18. Exercise: A vitally important prescription.

    Science.gov (United States)

    Hechanova, Rachel L; Wegler, Jennifer L; Forest, Christopher P

    2017-04-01

    Sedentary lifestyles and low physical activity have led to rising health concerns and increasing mortality risks. With the growing concern of the inactivity of adult Americans, it is important that physical activity be promoted to prevent disease and reduce health risks. This article reviews the benefits of physical activity and the steps that primary care providers should take to evaluate physical activity as the fifth vital sign in every patient encounter. The 5A's (assess, advise, agree, assist, and arrange) should be applied in order to implement an exercise prescription into the practice of medicine.

  19. Identifying vital edges in Chinese air route network via memetic algorithm

    Directory of Open Access Journals (Sweden)

    Wenbo Du

    2017-02-01

    Full Text Available Due to rapid development in the past decade, air transportation system has attracted considerable research attention from diverse communities. While most of the previous studies focused on airline networks, here we systematically explore the robustness of the Chinese air route network, and identify the vital edges which form the backbone of Chinese air transportation system. Specifically, we employ a memetic algorithm to minimize the network robustness after removing certain edges, and hence the solution of this model is the set of vital edges. Counterintuitively, our results show that the most vital edges are not necessarily the edges of the highest topological importance, for which we provide an extensive explanation from the microscope view. Our findings also offer new insights to understanding and optimizing other real-world network systems.

  20. Wind and Current Forces Acting on Canadian Forces Ships During Tug Operations

    Science.gov (United States)

    2002-11-01

    McTaggart and Sav- age [1] describe model tests conducted on a generic frigate model to determine wind forces influencing ship capsize. Van Manen and van ...Fn will be 0.06. Based on data presented by van Manen and van Oossanen [2], the fric- tional resistance coefficient will be approximately 0.002 and...Conference on Stability of Ships and Ocean Vehicles (Melbourne, Florida, 1994). 2. J.D. van Manen and P. van Oossanen, Principles of Naval Architecture, Volume

  1. Entrepreneurship education: a vital instrument for youth ...

    African Journals Online (AJOL)

    The concern of this paper is to explore Entrepreneurship Education (EE) as one of the vital tools for youth empowerment, industrial development and consolidation of national integration in Nigeria. To achieve this feat, the paper takes its roots from the role of EE in youth empowerment programmes, national integration and ...

  2. Poor quality vital anti-malarials in Africa - an urgent neglected public health priority

    Directory of Open Access Journals (Sweden)

    Newton Paul N

    2011-12-01

    Full Text Available Abstract Background Plasmodium falciparum malaria remains a major public health problem. A vital component of malaria control rests on the availability of good quality artemisinin-derivative based combination therapy (ACT at the correct dose. However, there are increasing reports of poor quality anti-malarials in Africa. Methods Seven collections of artemisinin derivative monotherapies, ACT and halofantrine anti-malarials of suspicious quality were collected in 2002/10 in eleven African countries and in Asia en route to Africa. Packaging, chemical composition (high performance liquid chromatography, direct ionization mass spectrometry, X-ray diffractometry, stable isotope analysis and botanical investigations were performed. Results Counterfeit artesunate containing chloroquine, counterfeit dihydroartemisinin (DHA containing paracetamol (acetaminophen, counterfeit DHA-piperaquine containing sildenafil, counterfeit artemether-lumefantrine containing pyrimethamine, counterfeit halofantrine containing artemisinin, and substandard/counterfeit or degraded artesunate and artesunate+amodiaquine in eight countries are described. Pollen analysis was consistent with manufacture of counterfeits in eastern Asia. These data do not allow estimation of the frequency of poor quality anti-malarials in Africa. Conclusions Criminals are producing diverse harmful anti-malarial counterfeits with important public health consequences. The presence of artesunate monotherapy, substandard and/or degraded and counterfeit medicines containing sub-therapeutic amounts of unexpected anti-malarials will engender drug resistance. With the threatening spread of artemisinin resistance to Africa, much greater investment is required to ensure the quality of ACTs and removal of artemisinin monotherapies. The International Health Regulations may need to be invoked to counter these serious public health problems.

  3. Mediating effect of Facebook addiction on the relationship between subjective vitality and subjective happiness.

    Science.gov (United States)

    Uysal, Recep; Satici, Seydi Ahmet; Akin, Ahmet

    2013-12-01

    This study examined the mediating effects of Facebook addiction on the relationship between subjective vitality and subjective happiness. 297 university students (157 women, 140 men; M age = 20.1 yr., SD = 1.3) were administered the Facebook Addiction Scale, the Subjective Vitality Scale, and the Subjective Happiness Scale. Hierarchical regression analysis showed that Facebook addiction partially mediated the relationship between subjective vitality and subjective happiness.

  4. CDC Vital Signs-Too Loud for Too Long!

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the February 2017 CDC Vital Signs report. Being around too much loud noise-like a leaf blower or rock concert-can cause permanent hearing loss. Learn how to prevent hearing loss.

  5. Ground Reaction Force and Mechanical Differences Between the Interim Resistive Exercise Device (iRED) and Smith Machine While Performing a Squat

    Science.gov (United States)

    Amonette, William E.; Bentley, Jason R.; Lee, Stuart M. C.; Loehr, James A.; Schneider, Suzanne

    2004-01-01

    Musculoskeletal unloading in microgravity has been shown to induce losses in bone mineral density, muscle cross-sectional area, and muscle strength. Currently, an Interim Resistive Exercise Device (iRED) is being flown on board the ISS to help counteract these losses. Free weight training has shown successful positive musculoskeletal adaptations. In biomechanical research, ground reaction forces (GRF) trajectories are used to define differences between exercise devices. The purpose of this evaluation is to quantify the differences in GRF between the iRED and free weight exercise performed on a Smith machine during a squat. Due to the differences in resistance properties, inertial loading and load application to the body between the two devices, we hypothesize that subjects using iRED will produce GRF that are significantly different from the Smith machine. There will be differences in bar/harness range of motion and the time when peak GRF occurred in the ROMbar. Three male subjects performed three sets of ten squats on the iRED and on the Smith Machine on two separate days at a 2-second cadence. Statistically significant differences were found between the two devices in all measured GRF variables. Average Fz and Fx during the Smith machine squat were significantly higher than iRED. Average Fy (16.82 plus or minus.23; p less than .043) was significantly lower during the Smith machine squat. The mean descent/ascent ratio of the magnitude of the resultant force vector of all three axes for the Smith machine and iRED was 0.95 and 0.72, respectively. Also, the point at which maximum Fz occurred in the range of motion (Dzpeak) was at different locations with the two devices.

  6. Forced deflation pulmonary function test: a novel method to evaluate lung function in infants and young children.

    Science.gov (United States)

    Goyal, Rakesh K; Ibrahimova, Azada; Escolar, Maria L; Szabolcs, Paul; Vander Lugt, Mark T.; Windreich, Randy M; Weiner, Daniel J

    2017-04-01

    We describe the safety and feasibility of a forced deflation pulmonary function test (dPFT) in infants and young children. Fifty-two dPFT studies were performed in 26 patients (median age, 1.4 years). Forced vital capacity (FVC) and forced expiratory flow (FEF 75 ) were normal in all except one case, but respiratory system compliance (Crs) was reduced in 24% patients. There were no significant differences in pre-blood and marrow transplantation FVC, FEF 75 , and Crs between those patients who did and those who did not have posttransplant pulmonary complications. A larger study is needed to determine the prevalence and significance of PFT abnormalities in this age group. © 2016 Wiley Periodicals, Inc.

  7. [Modifications of vital signs during hygiene care in intensive care patients: an explorative study].

    Science.gov (United States)

    Lucchini, Alberto; Giacovelli, Matteo; Elli, Stefano; Gariboldi, Roberto; Pelucchi, Giulia; Bondi, Herman; Brambilla, Daniela

    2009-01-01

    Hygiene care in critical patients may alter vital signs. Aim of this paper is to measure vital signs and their modifications in critical patients during hygiene care and measure differences with pre and post hygiene values. Vital signs of 6 patients two hours before, during and 90 minutes after hygienic care were measured. During and 2 hours after the end of hygiene a modification of vital signs was observed compared to basic values (mean values during/90 min after, compared to baseline): heart rate +11.20%/ +1.48; systolic blood pressure +22.68%/+1.56; arterial capillary saturimetry -4.31/+0.27, Respiratory frequency +8.10/+2.66, tidal volume +4,04/-7,51, CO2 min/vol +5,34/- 22.33, bladder temperature -0.85/-0.60. Hygiene care in critical care patients may significantly alter vital signs. Therefore a strict haemodinamic and respiratory monitoring is warranted as well as protocols for the management of sedation and of vasoactive support.

  8. How the nature of the chemical bond governs resistance to amorphization by radiation damage

    International Nuclear Information System (INIS)

    Trachenko, Kostya; Artacho, Emilio; Dove, Martin T.; Pruneda, J.M.

    2005-01-01

    We discuss what defines a material's resistance to amorphization by radiation damage. We propose that resistance is generally governed by the competition between the short-range covalent and long-range ionic forces, and we quantify this picture using quantum-mechanical calculations. We calculate the Voronoi deformation density charges and Mulliken overlap populations of 36 materials, representative of different families, including complex oxides. We find that the computed numbers generally follow the trends of experimental resistance in several distinct families of materials: the increase (decrease) of the short-range covalent component in material's total force field decreases (increases) its resistance

  9. Clinical relevance of routinely measured vital signs in hospitalized patients: a systematic review

    NARCIS (Netherlands)

    Storm-Versloot, Marja N.; Verweij, Lotte; Lucas, Cees; Ludikhuize, Jeroen; Goslings, J. Carel; Legemate, Dink A.; Vermeulen, Hester

    2014-01-01

    Conflicting evidence exists on the effectiveness of routinely measured vital signs on the early detection of increased probability of adverse events. To assess the clinical relevance of routinely measured vital signs in medically and surgically hospitalized patients through a systematic review.

  10. Experimental investigation of the effect of an electric field on heat transfers at boiling point for a high-resistivity water in forced convection

    International Nuclear Information System (INIS)

    Morin, Henri; Verdier, Jacques

    1964-10-01

    The enhancement of heat exchanges with boiling water in forced convection in an annular duct is studied when applying an electric field between the two walls of the duct. At the local boiling and at saturation temperature, for a water resistivity comprised between 0.5 and 1 M Ω cm, with fields on the cylindrical interior surface of the canal comprised between 4 and 8 kV/cm, significant enhancements of the exchanged heat fluxes are noticed, 2.5 to 10 time superior to exchanges without electric field. When heating, heat fluxes may be increased from two to three times [fr

  11. Single-cell force spectroscopy of pili-mediated adhesion

    Science.gov (United States)

    Sullan, Ruby May A.; Beaussart, Audrey; Tripathi, Prachi; Derclaye, Sylvie; El-Kirat-Chatel, Sofiane; Li, James K.; Schneider, Yves-Jacques; Vanderleyden, Jos; Lebeer, Sarah; Dufrêne, Yves F.

    2013-12-01

    Although bacterial pili are known to mediate cell adhesion to a variety of substrates, the molecular interactions behind this process are poorly understood. We report the direct measurement of the forces guiding pili-mediated adhesion, focusing on the medically important probiotic bacterium Lactobacillus rhamnosus GG (LGG). Using non-invasive single-cell force spectroscopy (SCFS), we quantify the adhesion forces between individual bacteria and biotic (mucin, intestinal cells) or abiotic (hydrophobic monolayers) surfaces. On hydrophobic surfaces, bacterial pili strengthen adhesion through remarkable nanospring properties, which - presumably - enable the bacteria to resist high shear forces under physiological conditions. On mucin, nanosprings are more frequent and adhesion forces larger, reflecting the influence of specific pili-mucin bonds. Interestingly, these mechanical responses are no longer observed on human intestinal Caco-2 cells. Rather, force curves exhibit constant force plateaus with extended ruptures reflecting the extraction of membrane nanotethers. These single-cell analyses provide novel insights into the molecular mechanisms by which piliated bacteria colonize surfaces (nanosprings, nanotethers), and offer exciting avenues in nanomedicine for understanding and controlling the adhesion of microbial cells (probiotics, pathogens).

  12. Comparison of Several Methods for Determining the Internal Resistance of Lithium Ion Cells

    Directory of Open Access Journals (Sweden)

    Hans-Georg Schweiger

    2010-06-01

    Full Text Available The internal resistance is the key parameter for determining power, energy efficiency and lost heat of a lithium ion cell. Precise knowledge of this value is vital for designing battery systems for automotive applications. Internal resistance of a cell was determined by current step methods, AC (alternating current methods, electrochemical impedance spectroscopy and thermal loss methods. The outcomes of these measurements have been compared with each other. If charge or discharge of the cell is limited, current step methods provide the same results as energy loss methods.

  13. Vital Signs-Physical Activity and Adults with Disabilities

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the May 2014 CDC Vital Signs report. Adults with disabilities who get no aerobic physical activity are 50 percent more likely to have heart disease, stroke, diabetes, or cancer. Learn what you can do to help.

  14. Fiber optic based multiparametric spectroscopy in vivo: Toward a new quantitative tissue vitality index

    Science.gov (United States)

    Kutai-Asis, Hofit; Barbiro-Michaely, Efrat; Deutsch, Assaf; Mayevsky, Avraham

    2006-02-01

    In our previous publication (Mayevsky et al SPIE 5326: 98-105, 2004) we described a multiparametric fiber optic system enabling the evaluation of 4 physiological parameters as indicators of tissue vitality. Since the correlation between the various parameters may differ in various pathophysiological conditions there is a need for an objective quantitative index that will integrate the relative changes measured in real time by the multiparametric monitoring system into a single number-vitality index. Such an approach to calculate tissue vitality index is critical for the possibility to use such an instrument in clinical environments. In the current presentation we are reporting our preliminary results indicating that calculation of an objective tissue vitality index is feasible. We used an intuitive empirical approach based on the comparison between the calculated index by the computer and the subjective evaluation made by an expert in the field of physiological monitoring. We used the in vivo brain of rats as an animal model in our current studies. The rats were exposed to anoxia, ischemia and cortical spreading depression and the responses were recorded in real time. At the end of the monitoring session the results were analyzed and the tissue vitality index was calculated offline. Mitochondrial NADH, tissue blood flow and oxy-hemoglobin were used to calculate the vitality index of the brain in vivo, where each parameter received a different weight, in each experiment type based on their significance. It was found that the mitochondrial NADH response was the main factor affected the calculated vitality index.

  15. Resistances in the first session of psychodrama psychotherapy group with adults.

    Science.gov (United States)

    Drakulić, Aleksandra Mindoljević

    2010-06-01

    Resistance refers to all types of behaviour that oppose the exploration processes in the therapeutic process and inhibit work. Very common types of resistances, such as forgetting the time of session, being late, non-payment of sessions and such are found in every type of psychotherapy, including psychodrama psychotherapy. The attempt to break resistance in order to evoke changes could be dangerous as it represents the necessary defence mechanism and it is also a vital element of the person's functioning in therapy. In psychodrama, which is a type of action method of group psychotherapy, resistance can manifest through continuous verbalization of problems, in not wanting to act out the problem, the protagonist's typical non-verbal message or the most obvious manifestation: the absence of the protagonist. This paper will be on the typical resistance which the therapist has noticed during the first session of psychodrama psychotherapy, with a small group of adult clients. As the group was young and with undeveloped cohesiveness, resistance represented a certain balancing power for maintaining mental homeostasis of the group.

  16. Superficie Específica y Estado Vital de la Materia

    Directory of Open Access Journals (Sweden)

    J. Hernando Ordoñez

    1992-03-01

    Full Text Available

    Se propone reemplazar el término de materia viva por el de estado vital de la materia por considerarlo adecuado, pues la materia es la misma, lo que cambia es su estado. Se estudia la relación entre la superficie específica y el estado vital de la materia. Constante del estado vital y el valor crítico de la superficie específica. Qué es la fuerza de inducción vital? Diferenciación funcional de las células. Cómo regula la unidad biológica su superficie específica? La materia que piensa es el fenómeno más grandioso de la creación.

    Sin entrar en disquisiciones sobre la naturaleza, manifestaciones y formas de la energía, me permito hacer unas a manera de divagaciones sobre los diferentes estados de la materia, que es una forma de la energía.

    Estados de la materia

    Sabemos que la mínima porción de la materia es el átomo, que tiene una composición compleja, que no es del caso estudiar. Los átomos pueden existir aislados y estar en lo que llamamos estado iónico. Si los átomos se juntan, forman moléculas, y su existencia constituye el estado molecular. Si las moléculas se juntan, forman complejos más grandes y tendremos las micelas, que constituyen el estado coloidal.

    Hasta aquí nuestros conocimientos nos son familiares, triviales. Pero hay un estado más complejo, en el cual entra materia en estado iónico, molecular y coloidal entrelazados entre sí, con propiedades totalmente diferentes. La materia en este estado adquiere caracteres extraordinarios tales como el de crecer, reproducirse, independizarse de las leyes físicas, puede autorregular su composición química, autorregular sus manifestaciones físicas, reaccionar ante los estímulos más variados, puede llegar hasta alturas inconcebibles integrando ideas. A este estado fue al que llamé en publicación anterior (1 estado vital, concepto que fue corroborado más ‘tarde por J.R. Brown (2 cuando me coment

  17. Poder vital e o legado de florence nightingale no processo saúdedoença: revisão integrativa The vital power and the legacy of florence nightingale in the health-disease process: integrative review

    Directory of Open Access Journals (Sweden)

    Marli Aparecida Rocha Souza

    2017-01-01

    Full Text Available Objetivo:.Caracterizar as evidências científicas nacionais dos últimos dez anos sobre Florence Nightingale e o poder vital e sua aplicabilidade na enfermagem, além de identificar os conceitos sobre poder vital. Método:.Revisão integrativa da literatura de artigos nacionais completos, por meio de quatro bases de dados. Foram selecionados sete artigos após a aplicação dos critérios de inclusão e exclusão. Da análise surgiram os temas sobre o legado de Florence e a ação do meio ambiente interno e externo sobre o poder vital. Resultados:.A maioria dos estudos focou o ambiente de inserção do indivíduo como fortalecer do poder vital e esta classificada como força interior. Conclusão:.Os profissionais de enfermagem ocupam um papel imprescindível na observação em manter o ambiente onde o paciente está inserido, favorecendo o fortalecimento do poder vital, destacando a presença do acompanhante como fortalecedor desse poder vital no processo de hospitalização.Descritores: Puerpério, Parto, Enfermagem.

  18. Vital Signs – Childhood Obesity

    Centers for Disease Control (CDC) Podcasts

    2013-08-06

    This podcast is based on the August 2013 CDC Vital Signs report. The rate of obesity among low-income preschoolers has declined, but one in eight is still obese. This program briefly discusses what can be done.  Created: 8/6/2013 by Centers for Disease Control and Prevention (CDC).   Date Released: 8/6/2013.

  19. Ten Propositions Regarding Space Power: The Dawn of a Space Force

    Science.gov (United States)

    2006-01-01

    perspective, space contributions z 97will account for an estimated $209 billion in 1947- 1950-T 1960-T 1970- 1980- 1990- the 2006 global economy. 2 4 50 60...Assessmu~t o ational awareiess, rhe transportation industry, A{,OaO{ dampaigns in 2010 and financial markers. 7TN PWOPSOI()S ] JWARII ’G SPA(E POWER 71...red, manner thot pmvteets one vital secnty intei blue, anI gray forces. The goal is rapid, acca - ests. We wil deter theati to our intrets, anid rate

  20. On the glitches in the force transmitted by an electrodynamic exciter to a structure

    Science.gov (United States)

    Rao, Dantam K.

    1987-01-01

    Around resonance, the force transmitted by an exciter into a structure will be smaller or greater than a reference force generated by its coils due to electromechanical interaction. A simple analysis is presented which reveals how this phenomenon of force drop-off is controlled by three factors. The first factor, called Armature Mass Factor, describes a purely mechanical interaction between the structure and the exciter. The electromechanical energy conversion and its interaction with the structure yields two additional factors, called Electrical Resistance and Electrical Inductance Factors. They describe the effects of coil resistance, inductance and magnetic field strength relative to structural damping and stiffness. Present analysis indicates that, under proper circumstances, more than 90 percent of the force drop-off can be eliminated if armature-to-structure mass ratio is smaller or equal to half of modal loss factor.

  1. The origins and drivers of insulin resistance.

    Science.gov (United States)

    Johnson, Andrew M F; Olefsky, Jerrold M

    2013-02-14

    Obesity-induced insulin resistance is the major determinant of metabolic syndrome, which precedes the development of type 2 diabetes mellitus and is thus the driving force behind the emerging diabetes epidemic. The precise causes of insulin resistance are varied, and the relative importance of each is a matter of ongoing research. Here, we offer a Perspective on the heterogeneous etiology of insulin resistance, focusing in particular on the role of inflammation, lipid metabolism, and the gastrointestinal microbiota. Copyright © 2013 Elsevier Inc. All rights reserved.

  2. Circuit Design of Surface Acoustic Wave Based Micro Force Sensor

    Directory of Open Access Journals (Sweden)

    Yuanyuan Li

    2014-01-01

    Full Text Available Pressure sensors are commonly used in industrial production and mechanical system. However, resistance strain, piezoresistive sensor, and ceramic capacitive pressure sensors possess limitations, especially in micro force measurement. A surface acoustic wave (SAW based micro force sensor is designed in this paper, which is based on the theories of wavelet transform, SAW detection, and pierce oscillator circuits. Using lithium niobate as the basal material, a mathematical model is established to analyze the frequency, and a peripheral circuit is designed to measure the micro force. The SAW based micro force sensor is tested to show the reasonable design of detection circuit and the stability of frequency and amplitude.

  3. Vitality at work and its associations with lifestyle, self-determination, organizational culture, and with employees' performance and sustainable employability.

    Science.gov (United States)

    van Scheppingen, Arjella R; de Vroome, Ernest M M; Ten Have, Kristin C J M; Zwetsloot, Gerard I J M; Wiezer, Noortje; van Mechelen, Willem

    2015-01-01

    Vitality at work is an important factor for optimal functioning and sustainable employability. To date, knowledge on how to promote vitality at work is fragmented. Contribute to knowledge on how to promote vitality at work. Determinants of vitality at work are identified from three scientific fields, and used in a comprehensive model. Regression analyses on cross-sectional data from a Dutch dairy company (N= 629) are performed to examine the associations between these factors, vitality at work, and employees' perceived effective personal functioning and sustainable employability. Vitality at work is most strongly associated with basic psychological needs of self-determination, but also with healthy lifestyle behavior, having a balanced workstyle, and social capital. Vitality at work is also associated with effective personal functioning and with sustainable employability. The study confirms the multifactorial nature of vitality at work. Since organizational culture may support self-determination, and cultural aspects themselves are positively associated with vitality, organizational culture seems particular important in promoting vitality at work. Additionally, a healthy lifestyle appears important. The associations between vitality at work and effective personal functioning and sustainable employability endorse the combined health-based, business-related and societal importance of vitality at work.

  4. Crack Driving Forces in a Multilayered Coating System for Ceramic Matrix Composite Substrates

    Science.gov (United States)

    Ghosn, Louis J.; Zhu, Dongming; Miller, Robert A.

    2005-01-01

    The effects of the top coating thickness, modulus and shrinkage strains on the crack driving forces for a baseline multilayer Yttria-Stabilized-Zirconia/Mullite/Si thermal and environment barrier coating (TEBC) system for SiC/SiC ceramic matrix composite substrates are determined for gas turbine applications. The crack driving forces increase with increasing modulus, and a low modulus thermal barrier coating material (below 10 GPa) will have no cracking issues under the thermal gradient condition analyzed. Since top coating sintering increases the crack driving forces with time, highly sintering resistant coatings are desirable to maintain a low tensile modulus and maintain a low crack driving force with time. Finite element results demonstrated that an advanced TEBC system, such as ZrO2/HfO2, which possesses improved sintering resistance and high temperature stability, exhibited excellent durability. A multi-vertical cracked structure with fine columnar spacing is an ideal strain tolerant coating capable of reducing the crack driving forces to an acceptable level even with a high modulus of 50 GPa.

  5. Vital Signs – Prescription Painkiller Overdoses

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the July 2013 CDC Vital Signs report. Prescription painkiller overdoses are an under-recognized and growing problem among women. This program includes things that women and health care providers can do to reduce the risk of overdose.

  6. Expert Talks: Understanding civil registration and vital statistics ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2017-09-13

    Sep 13, 2017 ... Case studies and successes in CRVS reform. Cambodia, New Zealand, Peru, Uganda, and others offer important lessons in strengthening civil registration and vital statistics systems. These interviews feature innovative case studies that have led to new and improved CRVS approaches.

  7. Identifying the optimal resistive load for complex training in male rugby players.

    Science.gov (United States)

    Comyns, Thomas M; Harrison, Andrew J; Hennessy, Liam; Jensen, Randall L

    2007-01-01

    Alternating a resistance exercise with a plyometric exercise is referred to as "complex training". In this study, we examined the effect of various resistive loads on the biomechanics of performance of a fast stretch-shortening cycle activity to determine if an optimal resistive load exists for complex training. Twelve elite rugby players performed three drop jumps before and after three back squat resistive loads of 65%, 80%, and 93% of a single repetition maximum (1-RM) load. All drop jumps were performed on a specially constructed sledge and force platform apparatus. Flight time, ground contact time, peak ground reaction force, reactive strength index, and leg stiffness were the dependent variables. Repeated-measures analysis of variance found that all resistive loads reduced (P benefit performance. However, it is unknown if these acute changes will produce any long-term adaptations to muscle function.

  8. Vitality of oligozoospermic semen samples is improved by both swim-up and density gradient centrifugation before cryopreservation.

    Science.gov (United States)

    Counsel, Madeleine; Bellinge, Rhys; Burton, Peter

    2004-05-01

    To ascertain whether washing sperm from oligozoospermic and normozoospermic samples before cryopreservation improves post-thaw vitality. Normozoospermic (n = 18) and oligozoospermic (n = 16) samples were divided into three aliquots. The first aliquot remained untreated and the second and third aliquots were subjected to the swim-up and discontinuous density gradient sperm washing techniques respectively. Vitality staining was performed, samples mixed with cryopreservation media and frozen. Spermatozoa were thawed, stained, and vitality quantified and expressed as the percentage of live spermatozoa present. Post-thaw vitality in untreated aliquots from normozoospermic samples (24.9% +/- 2.3; mean +/- SEM) was significantly higher (unpaired t-tests; P vitality was significantly higher after swim-up in normozoospermic samples (35.6% +/- 2.1; P vitality in oligozoospermic (22.4% +/- 1.0; P vitality in cryopreserved oligozoospermic samples was improved by both the swim-up and density gradient centrifugation washing techniques prior to freezing.

  9. TIROTOXICOSIS GESTACIONAL: PATOLOGIA CON RIESGO VITAL

    OpenAIRE

    Valdés R.,Enrique; Pilasi M.,Carlos; Núñez U.,Tatiana

    2003-01-01

    Se presenta un caso clínico con diagnóstico final de Tirotoxicosis gestacional que debuta con una complicación excepcional, insuficiencia cardíaca congestiva e hipertensión pulmonar severa. Se presenta la experiencia del Hospital Clínico de la Universidad de Chile, proponiendo que su diagnóstico y tratamiento oportunos son la base del pronóstico de esta patología de riesgo vital para el binomio madre-hijo

  10. CDC Vital Signs- Proteja a los pacientes contra la resistencia a los antibióticos (Protect Patients from Antibiotic Resistance)

    Centers for Disease Control (CDC) Podcasts

    2016-03-03

    Este podcast se basa en la edición de marzo del 2016 del informe Signos Vitales de los CDC. Mientras reciben atención médica en un centro hospitalario, los pacientes pueden contraer infecciones graves asociadas a la atención médica. Infórmese sobre cómo prevenir las infecciones asociadas a la atención médica.  Created: 3/3/2016 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 3/3/2016.

  11. Effect of inclusion of SiC particulates on the mechanical resistance behaviour of stir-cast AA6063/SiC composites

    International Nuclear Information System (INIS)

    Balasubramanian, I.; Maheswaran, R.

    2015-01-01

    Highlights: • AA6063/SiC composites with different weight percent are stir cast. • Resistance properties against indentation, stretching force and sliding force are studied. • Increase in initiation of cleavage facets and reduces the tensile strength for 15% SiC. • Transition from micro ploughing to micro cutting wear mechanism is less due to SiC inclusion. - Abstract: This study investigates the mechanical resistance behaviour of AA6063 particulate composites with the inclusion of micron-sized silicon carbide (SiC) particles with different weight percentages in an AA6063 aluminium matrix. AA6063/SiC particulate composites containing 0, 5, 10, and 15 weight percent of SiC particles were produced by stir casting. Standard mechanical tests were conducted on the composite plates, and the mechanical resistance to indentation, tensile force and sliding force are evaluated. It has been observed that upon addition of SiC particles, the resistance against indentation is increased and the resistance against tensile force is initially increased and then decreased. Furthermore, using scanning electron microscopy (SEM), the fracture appearance of the broken specimen subjected to tensile force and morphological changes in the surface subjected to sliding force are analysed. The SEM images reveal that the addition of SiC particles in the AA6063 aluminium matrix initiates more cleavage facets. This leads to brittle fracture in the specimen subjected to tensile forces and less transition from material displacement to material removal in the specimen subjected to sliding forces

  12. The cross-cultural importance of satisfying vital needs.

    Science.gov (United States)

    Alvarez, Allen Andrew A

    2009-11-01

    Ethical beliefs may vary across cultures but there are things that must be valued as preconditions to any cultural practice. Physical and mental abilities vital to believing, valuing and practising a culture are such preconditions and it is always important to protect them. If one is to practise a distinct culture, she must at least have these basic abilities. Access to basic healthcare is one way to ensure that vital abilities are protected. John Rawls argued that access to all-purpose primary goods must be ensured. Amartya Sen and Martha Nussbaum claim that universal capabilities are what resources are meant to enable. Len Doyal and Ian Gough identify physical health and autonomy as basic needs of every person in every culture. When we disagree on what to prioritize, when resources to satisfy competing demands are scarce, our common needs can provide a point of normative convergence. Need-based rationing, however, has been criticized for being too indeterminate to give guidance for deciding which healthcare services to prioritize and for tending to create a bottomless-pit problem. But there is a difference between needing something (first-order need) and needing to have the ability to need (second-order need). Even if we disagree about which first-order need to prioritize, we must accept the importance of satisfying our second-order need to have the ability to value things. We all have a second-order need for basic healthcare as a means to protect our vital abilities even if we differ in what our cultures consider to be particular first-order needs.

  13. Measurement of internal forces in superconducting accelerator magnets with strain gauge transducers

    International Nuclear Information System (INIS)

    Goodzeit, C.L.; Anerella, M.D.; Ganetis, G.L.

    1988-01-01

    An improved method has been developed for the measurement of internal forces in superconducting accelerator magnets, in particular the compressive stresses in coils and the end restraint forces on the coils. The transducers have been designed to provide improved sensitivity to purely mechanical strain by using bending mode deflections for sensing the applied loads. Strain gauge resistance measurements are made with a new system that eliminates sources of errors due to spurious resistance changes in interconnecting wiring and solder joints. The design of the transducers and their measurement system is presented along with a discussion of the method of compensation for thermal and magnetic effects, methods of calibration with typical calibration data, and measured effect in actual magnets of the thermal stress changes from cooldown and the Lorentz forces during magnet excitation. 13 figs., 1 tab

  14. The analysis of cable forces based on natural frequency

    Science.gov (United States)

    Suangga, Made; Hidayat, Irpan; Juliastuti; Bontan, Darwin Julius

    2017-12-01

    A cable is a flexible structural member that is effective at resisting tensile forces. Cables are used in a variety of structures that employ their unique characteristics to create efficient design tension members. The condition of the cable forces in the cable supported structure is an important indication of judging whether the structure is in good condition. Several methods have been developed to measure on site cable forces. Vibration technique using correlation between natural frequency and cable forces is a simple method to determine in situ cable forces, however the method need accurate information on the boundary condition, cable mass, and cable length. The natural frequency of the cable is determined using FFT (Fast Fourier Transform) Technique to the acceleration record of the cable. Based on the natural frequency obtained, the cable forces then can be determine by analytical or by finite element program. This research is focus on the vibration techniques to determine the cable forces, to understand the physical parameter effect of the cable and also modelling techniques to the natural frequency and cable forces.

  15. Rolling resistance and propulsion efficiency of manual and power-assisted wheelchairs.

    Science.gov (United States)

    Pavlidou, Efthymia; Kloosterman, Marieke G M; Buurke, Jaap H; Rietman, Johan S; Janssen, Thomas W J

    2015-11-01

    Rolling resistance is one of the main forces resisting wheelchair propulsion and thus affecting stress exerted on the upper limbs. The present study investigates the differences in rolling resistance, propulsion efficiency and energy expenditure required by the user during power-assisted and manual propulsion. Different tire pressures (50%, 75%, 100%) and two different levels of motor assistance were tested. Drag force, energy expenditure and propulsion efficiency were measured in 10 able-bodied individuals under different experimental settings on a treadmill. Results showed that drag force levels were significantly higher in the 50%, compared to the 75% and 100% inflation conditions. In terms of wheelchair type, the manual wheelchair displayed significantly lower drag force values than the power-assisted one. The use of extra-power-assisted wheelchair appeared to be significantly superior to conventional power-assisted and manual wheelchairs concerning both propulsion efficiency and energy expenditure required by the user. Overall, the results of the study suggest that the use of power-assisted wheelchair was more efficient and required less energy input by the user, depending on the motor assistance provided. Copyright © 2015 IPEM. Published by Elsevier Ltd. All rights reserved.

  16. Frictional Resistance of Three Types of Ceramic Brackets

    Directory of Open Access Journals (Sweden)

    Claire L Williams

    2014-01-01

    Full Text Available Objectives: To investigate the static frictional resistance at the bracket/archwire interface in two recently introduced bracket systems and compare them to conventional ceramic and conventional metal bracket systems. Three variables were considered including the bracket system, archwire type and archwire angulation. Material and Methods: Four bracket systems were tested in vitro: Self ligating ceramic, ceramic with metal slot and module, conventional ceramic with module and conventional metal with module. A specially constructed jig and an Instron testing machine were used to measure the static frictional resistance for 0.014 inches round and 0.018 x 0.025 inches rectangular stainless steel wires at 0° and 7° angulations. Main outcome measures: static frictional force at the bracket/archwire interface; recorded and measured in units of force (Newtons. Results: Self ligating ceramic and metal slot ceramic bracket systems generated significantly less static frictional resistance than conventional ceramic bracket systems with the wire at both angulations (P < 0.05. Changing the wire from 0.014 round to 0.018 x 0.025 rectangular wire significantly increased frictional forces for metal slot ceramic and conventional metal bracket systems (P < 0.01. Increasing wire angulation significantly increased frictional resistance at the bracket/archwire interface for all four types of bracket systems tested (P < 0.001. Conclusions: Compared to conventional ceramic, self ligating ceramic and metal slot ceramic bracket systems should give improved clinical performance, matching that of conventional metal brackets.

  17. Vitality preservation of an anomalous maxillary central incisor after endodontic therapy.

    Science.gov (United States)

    Kaufman, A Y; Kaffe, I; Littner, M M

    1984-06-01

    Endodontic treatment of a case of fused immature central incisor with a supernumerary tooth with dens in dente is described. Although a chronic dentoalveolar abscess was diagnosed, vitality test signs were positive. Treatment consisted of pulpotomy with calcium hydroxide paste; after 2 1/2 months a permanent root canal filling was placed in the amputated part. Follow-up 2 years postoperatively indicated that the tooth has maintained its vitality. The periapical area is completely healed, and apical closure is evident.

  18. CDC Vital Signs-Hospital Actions Affect Breastfeeding

    Centers for Disease Control (CDC) Podcasts

    2015-10-06

    This podcast is based on the October 2015 CDC Vital Signs report. Hospitals can implement the Ten Steps to Successful Breastfeeding to be designated as "Baby-Friendly" and support more moms in a decision to breastfeed.  Created: 10/6/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 10/6/2015.

  19. Pharmacy faculty workplace issues: findings from the 2009-2010 COD-COF Joint Task Force on Faculty Workforce.

    Science.gov (United States)

    Desselle, Shane P; Peirce, Gretchen L; Crabtree, Brian L; Acosta, Daniel; Early, Johnnie L; Kishi, Donald T; Nobles-Knight, Dolores; Webster, Andrew A

    2011-05-10

    Many factors contribute to the vitality of an individual faculty member, a department, and an entire academic organization. Some of the relationships among these factors are well understood, but many questions remain unanswered. The Joint Task Force on Faculty Workforce examined the literature on faculty workforce issues, including the work of previous task forces charged by the American Association of Colleges of Pharmacy (AACP). We identified and focused on 4 unique but interrelated concepts: organizational culture/climate, role of the department chair, faculty recruitment and retention, and mentoring. Among all 4 resides the need to consider issues of intergenerational, intercultural, and gender dynamics. This paper reports the findings of the task force and proffers specific recommendations to AACP and to colleges and schools of pharmacy.

  20. Comparison of the Resistance to Bending Forces of the 4.5 LCP Plate-rod Construct and of 4.5 LCP Alone Applied to Segmental Femoral Defects in Miniature Pigs

    Directory of Open Access Journals (Sweden)

    Lucie Urbanová

    2010-01-01

    Full Text Available The study deals with the determination of mechanical properties, namely resistance to bending forces, of flexible buttress osteosynthesis using two different bone-implant constructs stabilizing experimental segmental femoral bone defects (segmental ostectomy in a miniature pig ex vivo model using 4.5 mm titanium LCP and a 3 mm intramedullary pin (“plate and rod” construct (PR-LCP, versus the 4.5 mm titanium LCP alone (A-LCP. The “plate and rod” fixation (PR-LCP of the segmental femoral defect is significantly more resistant (p in vivo experiments in the miniature pig to investigate bone defect healing after transplantation of mesenchymal stem cells in combination with biocompatible scaffolds.

  1. VITAL: Vanguard Investigations of Therapeutic Approaches to Lung Cancer

    National Research Council Canada - National Science Library

    Hong, Waun K; Lotan, Reuben; Stewart, David

    2006-01-01

    .... In addition, the clinical trials that will be conducted in the VITAL Research Program will demonstrate the true rate of lung cancer recurrence and second primary tumor incidence in patients at high...

  2. Vital Signs-Cervical Cancer is Preventable!

    Centers for Disease Control (CDC) Podcasts

    2014-11-05

    This podcast is based on the November 2014 CDC Vital Signs report. Every visit to a doctor or nurse is an opportunity to prevent cervical cancer. Women can get a Pap test and HPV test to help prevent cervical cancer and adolescent boys and girls can get the HPV vaccination series to help prevent cervical and other cancers.  Created: 11/5/2014 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 11/5/2014.

  3. Entropy resistance minimization: An alternative method for heat exchanger analyses

    International Nuclear Information System (INIS)

    Cheng, XueTao

    2013-01-01

    In this paper, the concept of entropy resistance is proposed based on the entropy generation analyses of heat transfer processes. It is shown that smaller entropy resistance leads to larger heat transfer rate with fixed thermodynamic force difference and smaller thermodynamic force difference with fixed heat transfer rate, respectively. For the discussed two-stream heat exchangers in which the heat transfer rates are not given and the three-stream heat exchanger with prescribed heat capacity flow rates and inlet temperatures of the streams, smaller entropy resistance leads to larger heat transfer rate. For the two-stream heat exchangers with fixed heat transfer rate, smaller entropy resistance leads to larger effectiveness. Furthermore, it is shown that smaller values of the concepts of entropy generation numbers and modified entropy generation number do not always correspond to better performance of the discussed heat exchangers. - Highlights: • The concept of entropy resistance is defined for heat exchangers. • The concepts based on entropy generation are used to analyze heat exchangers. • Smaller entropy resistance leads to better performance of heat exchangers. • The applicability of entropy generation minimization is conditional

  4. Home telemonitoring of vital signs--technical challenges and future directions.

    Science.gov (United States)

    Celler, Branko G; Sparks, Ross S

    2015-01-01

    The telemonitoring of vital signs from the home is an essential element of telehealth services for the management of patients with chronic conditions, such as congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), diabetes, or poorly controlled hypertension. Telehealth is now being deployed widely in both rural and urban settings, and in this paper, we discuss the contribution made by biomedical instrumentation, user interfaces, and automated risk stratification algorithms in developing a clinical diagnostic quality longitudinal health record at home. We identify technical challenges in the acquisition of high-quality biometric signals from unsupervised patients at home, identify new technical solutions and user interfaces, and propose new measurement modalities and signal processing techniques for increasing the quality and value of vital signs monitoring at home. We also discuss use of vital signs data for the automated risk stratification of patients, so that clinical resources can be targeted to those most at risk of unscheduled admission to hospital. New research is also proposed to integrate primary care, hospital, personal genomic, and telehealth electronic health records, and apply predictive analytics and data mining for enhancing clinical decision support.

  5. Impact of thermal stress on evolutionary trajectories of pathogen resistance in three-spined stickleback (Gasterosteus aculeatus).

    Science.gov (United States)

    Schade, Franziska M; Shama, Lisa N S; Wegner, K Mathias

    2014-07-26

    Pathogens are a major regulatory force for host populations, especially under stressful conditions. Elevated temperatures may enhance the development of pathogens, increase the number of transmission stages, and can negatively influence host susceptibility depending on host thermal tolerance. As a net result, this can lead to a higher prevalence of epidemics during summer months. These conditions also apply to marine ecosystems, where possible ecological impacts and the population-specific potential for evolutionary responses to changing environments and increasing disease prevalence are, however, less known. Therefore, we investigated the influence of thermal stress on the evolutionary trajectories of disease resistance in three marine populations of three-spined sticklebacks Gasterosteus aculeatus by combining the effects of elevated temperature and infection with a bacterial strain of Vibrio sp. using a common garden experiment. We found that thermal stress had an impact on fish weight and especially on survival after infection after only short periods of thermal acclimation. Environmental stress reduced genetic differentiation (QST) between populations by releasing cryptic within-population variation. While life history traits displayed positive genetic correlations across environments with relatively weak genotype by environment interactions (GxE), environmental stress led to negative genetic correlations across environments in pathogen resistance. This reversal of genetic effects governing resistance is probably attributable to changing environment-dependent virulence mechanisms of the pathogen interacting differently with host genotypes, i.e. GPathogenxGHostxE or (GPathogenxE)x(GHostxE) interactions, rather than to pure host genetic effects, i.e. GHostxE interactions. To cope with climatic changes and the associated increase in pathogen virulence, host species require wide thermal tolerances and pathogen-resistant genotypes. The higher resistance we found

  6. Apexification in a non-vital tooth: By control of infection

    Directory of Open Access Journals (Sweden)

    Basgauda R Patil

    2010-01-01

    Full Text Available Endodontic management of immature non-vital permanent teeth in young pediatric patients is a great challenge to dentists. When the pulp of an incompletely formed tooth loses its vitality, then the entire root system has also lost its ability to continue to develop. The walls of the root canals are frequently divergent and open apices make debridement and obturation difficult. Thus, closure of the root apex is very essential for the success of endodontic treatment. Many different materials are used for the apexification procedure, for apical barrier formation and healing. However, in this present case the apical closure was achieved only by means of infection control.

  7. Protection of swimming-induced oxidative stress in some vital ...

    African Journals Online (AJOL)

    Protection of swimming-induced oxidative stress in some vital organs by the treatment of composite extract of Withania somnifera, Ocimum sanctum and Zingiber officinalis in male rat. D Misra, B Maiti, D Ghosh ...

  8. Vital Signs – Alcohol Screening and Counseling?

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the January 2014 CDC Vital Signs report. Millions of Americans drink too much, a dangerous behavior that can lead to serious health problems. Alcohol screening and counseling can help.

  9. Future orientation and health quality of life in primary care: vitality as a mediator.

    Science.gov (United States)

    Hirsch, Jameson K; Molnar, Danielle; Chang, Edward C; Sirois, Fuschia M

    2015-07-01

    Temporal perspective, including views about future goals, may influence motivational processes related to health. An adaptive sense of future orientation is linked to better health, but little research has examined potential underlying factors, such as vitality. In a sample of 101 primary care patients, we examined whether belief in the changeability of the future was related to mental and physical energization and, in turn, to health-related quality of life. Participants were working, uninsured primary care patients, who completed self-report measures of future orientation, vitality, and health-related quality of life. Mediation models, covarying age, sex, and race/ethnicity indicated that vitality significantly mediated the association between future orientation and the outcomes of general health, mental health, social functioning, bodily pain, and role limitations due to emotional and physical reasons. Vitality exerted an indirect-only effect on the relation between future orientation and physical functioning. Our findings suggest that adaptive beliefs about the future may promote, or allow access to, physical and mental energy and, in turn, may result in better mental and physical health functioning. Individual-level and public health interventions designed to promote future orientation and vitality may beneficially influence quality of life and well-being.

  10. Comparison of vitality states of finishers and withdrawers in trail running: An enactive and phenomenological perspective.

    Directory of Open Access Journals (Sweden)

    Nadège Rochat

    Full Text Available Studies on ultra-endurance suggest that during the races, athletes typically experience three vitality states (i.e., preservation, loss, and revival at the phenomenological level. Nevertheless, how these states contribute to the management and outcome of performance remains unclear. The aim of this study was to determine whether and how the vitality states experienced by runners and their evolution during a trail race can be used to distinguish finishers from withdrawers. From an enactive and phenomenological framework, we processed enactive interviews and blog posts of race narratives. We distinguished units of meaning, which were grouped into sequences of experience; each sequence was then categorized as one of the three vitality states: state of vitality preservation (SVP, state of vitality loss (SVL or state of vitality revival (SVR. We analyzed the distribution of these vitality states and their temporal organization at the beginning, in the second and third quarters, and at the end of the races, and we qualitatively characterized runners' adaptations to SVL. Results showed that finishers completed the race in SVP, with overall significantly more sequences in SVP and significantly fewer sequences in SVL than withdrawers. SVR did not discriminate finishers from withdrawers. The temporal organization of the vitality states showed a significant difference in the emergence of SVP from the second quarter of the race, as well as a significant difference in the emergence of SVL from the third quarter of the race. The analysis of adaptations to SVL confirmed that finishers were more capable of exiting SVL by enacting a preservation world when they felt physical or psychological alerts, whereas withdrawers remained in SVL. Our results showed that finishers and withdrawers did not enact the same phenomenological worlds in the race situation, especially in the organization of vitality adaptations and their relationships to difficulties; the cumulative

  11. CDC Signos Vitales: Enfermedad del legionario (CDC Vital Signs–Legionnaires’ Disease)

    Centers for Disease Control (CDC) Podcasts

    Este podcast se basa en la edición de junio del 2016 del informe Signos Vitales de los CDC. Las personas pueden contraer la enfermedad del legionario, un tipo grave de infección pulmonar, al inhalar pequeñas gotitas de agua contaminada con bacterias Legionella. Obtenga más información sobre lo que se puede hacer para ayudar a prevenir brotes de enfermedad del legionario y mantener seguras a las personas.

  12. Internet skills : vital assets in an information society

    NARCIS (Netherlands)

    van Deursen, Alexander Johannes Aloisius Maria

    2010-01-01

    Internet Skills, vital assets in an information society starts with a brief history of communication technologies. It appears that in the course of history, these technologies have changed and have put increasing demands on the people that use them. Moreover, the stakes for not being able to keep up

  13. Ethnolinguistic Vitality among Japanese-Brazilians: Challenges and Possibilities

    Science.gov (United States)

    Sakamoto, Mitsuyo; Matsubara Morales, Leiko

    2016-01-01

    This paper explores ethnolinguistic vitality among Japanese-Brazilians ("Nikkeis"). First, an 18-item questionnaire was administered to 33 individuals who attended a seminar on bilingual studies held in São Paulo. Then, two bilingual "Nikkei" teachers who participated in the questionnaire and who grew up to be bilinguals…

  14. CDC Vital Signs-Safer Food Saves Lives

    Centers for Disease Control (CDC) Podcasts

    2015-11-03

    This podcast is based on the November 2015 CDC Vital Signs report. Contaminated food sent to several states can cause multistate outbreaks of foodborne illness and make a lot of people seriously ill. Learn what can be done to prevent and stop outbreaks.  Created: 11/3/2015 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 11/3/2015.

  15. Vital Signs - Antibiotic RX in Hospitals: Proceed with Caution

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the March 2014 CDC Vital Signs report. Antibiotics save lives, but poor prescribing practices can put patients at risk for health problems. Learn how to protect patients by protecting antibiotics.

  16. Vital affordances, occupying niches

    DEFF Research Database (Denmark)

    Dokumaci, Arseli

    2017-01-01

    This article proposes a new conceptual approach to disability and performance through a contribution that comes entirely from outside the disciplines; a re-theorisation of Gibson’s [1979. The Ecological Approach to Visual Perception. Hillsdale: Lawrence Erlbaum Associates] theory of affordances....... Drawing on three visual ethnographies with differently disabled individuals, and building upon my previous consideration of performance as ‘affordance creation’ in itself [Dokumaci, A. 2013. “On Falling Ill.” Performance Research 18 (4): 107–115], the article conceptualises affordances as a form of micro......-activism–one that can allow us to unpack the entanglements of disability, performance, and matter. Putting Gibson’s theory in conversation with Canguilhem’s philosophy of life, it proposes the concept ‘vital affordances’ as a new way to think through this micro-activism, and the way disabled individuals might transform...

  17. Contractile Force of Human Extraocular Muscle: A Theoretical Analysis

    Directory of Open Access Journals (Sweden)

    Hongmei Guo

    2016-01-01

    Full Text Available Aim. The length-contractile force relationships of six human extraocular muscles (EOMs in primary innervations should be determined during eye movement modeling and surgery of clinical EOMs. This study aims to investigate these relationships. Method. The proposal is based on the assumption that six EOMs have similar constitutive relationships, with the eye suspended in the primary position. The constitutive relationships of EOMs are obtained by optimizing from previous experimental data and the theory of mechanical equilibrium using traditional model. Further, simulate the existing experiment of resistance force, and then compare the simulated results with the existing experimental results. Finally, the mechanical constitutive relationships of EOMs are obtained. Results. The results show that the simulated resistance forces from the other four EOMs except for the horizontal recti well agree with previous experimental results. Conclusion. The mechanical constitutive relationships of six EOMs in primary innervations are obtained, and the rationality of the constitutive relationships is verified. Whereafter, the active stress-strain relationships of the six EOMs in the primary innervations are obtained. The research results can improve the eye movement model to predict the surgical amounts of EOMs before EOM surgery more precisely.

  18. Energy, fatigue, or both? A bifactor modeling approach to the conceptualization and measurement of vitality.

    Science.gov (United States)

    Deng, Nina; Guyer, Rick; Ware, John E

    2015-01-01

    Vitality is an important domain reflecting both the physical and emotional components of health-related quality of life. Because of its complexity, it has been defined and measured both broadly and narrowly. We explored the dimensionality of a very comprehensive item bank hypothesized to measure vitality and its related concepts. Secondary analyses were conducted using the responses of 1,343 adults representative of the US general population to Internet-based surveys including 42 items compiled from multiple scales (e.g., SF-36 Vitality, PROMIS-Fatigue), covering a broad range of vitality-related content areas (energy, fatigue, and their interference with physical, mental, social activities, and quality of life). Exploratory and confirmatory factor models were evaluated independently using split-half samples. Bifactor model was used to assess the essential unidimensionality of the items, in comparison with traditional unidimensional, multidimensional, and hierarchical models. Method effects of a common scale or phrase were modeled via correlating errors. The exploratory factor analysis identified one dominant factor. The confirmatory factor analysis identified a best-fitting (CFI = 0.964, RMSEA = 0.084) bifactor model with one general (vitality) and two group (energy and fatigue) factors, explaining 69, 3, and 4 % of total variance. Correlating errors accounting for the method effects were important in identifying the substantive dimensionality of the items. The bifactor model proved to be useful for evaluating the dimensionality of a complex construct. Results supported conceptualizing and measuring vitality as a unidimensional energy-fatigue construct. We encourage future studies comparing practical implications of measures based on the broader and narrower conceptualizations of vitality.

  19. Harnessing Resistance: Using the Theory of Constraints To Assist Change Management.

    Science.gov (United States)

    Mabin, Victoria J.; Forgeson, Steve; Green, Lawrence

    2001-01-01

    Applies the Theory of Constraints, which views resistance to change as a necessary, positive force, to a case study of a bank merger. For each resistance factor, the theory provides tools for using it and managing change successfully. (Contains 46 references.) (SK)

  20. Comparison of force exerted on the sternum during a sneeze versus during low-, moderate-, and high-intensity bench press resistance exercise with and without the valsalva maneuver in healthy volunteers.

    Science.gov (United States)

    Adams, Jenny; Schmid, Jack; Parker, Robert D; Coast, J Richard; Cheng, Dunlei; Killian, Aaron D; McCray, Stephanie; Strauss, Danielle; McLeroy Dejong, Sandra; Berbarie, Rafic

    2014-03-15

    Sternal precautions are intended to prevent complications after median sternotomy, but little data exist to support the consensus recommendations. To better characterize the forces on the sternum that can occur during everyday events, we conducted a prospective nonrandomized study of 41 healthy volunteers that evaluated the force exerted during bench press resistance exercise and while sneezing. A balloon-tipped esophageal catheter, inserted through the subject's nose and advanced into the thoracic cavity, was used to measure the intrathoracic pressure differential during the study activities. After the 1 repetition maximum (1-RM) was assessed, the subject performed the bench press at the following intensities, first with controlled breathing and then with the Valsalva maneuver: 40% of 1-RM (low), 70% of 1-RM (moderate), and 1-RM (high). Next, various nasal irritants were used to induce a sneeze. The forces on the sternum were calculated according to a cylindrical model, and a 2-tailed paired t test was used to compare the mean force exerted during a sneeze with the mean force exerted during each of the 6 bench press exercises. No statistically significant difference was found between the mean force from a sneeze (41.0 kg) and the mean total force exerted during moderate-intensity bench press exercise with breathing (41.4 kg). In conclusion, current guidelines and recommendations limit patient activity after a median sternotomy. Because these patients can repeatedly withstand a sneeze, our study indicates that they can withstand the forces from more strenuous activities than are currently allowed. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Phantom force induced by tunneling current: a characterization on Si(111).

    Science.gov (United States)

    Weymouth, A J; Wutscher, T; Welker, J; Hofmann, T; Giessibl, F J

    2011-06-03

    Simultaneous measurements of tunneling current and atomic forces provide complementary atomic-scale data of the electronic and structural properties of surfaces and adsorbates. With these data, we characterize a strong impact of the tunneling current on the measured force on samples with limited conductivity. The effect is a lowering of the effective gap voltage through sample resistance which in turn lowers the electrostatic attraction, resulting in an apparently repulsive force. This effect is expected to occur on other low-conductance samples, such as adsorbed molecules, and to strongly affect Kelvin probe measurements when tunneling occurs.

  2. CDC Vital Signs–Opioid Prescribing

    Centers for Disease Control (CDC) Podcasts

    2017-07-06

    This podcast is based on the July 2017 CDC Vital Signs report. Higher opioid prescribing puts patients at risk for addiction and overdose. Learn what can be done about this serious problem.  Created: 7/6/2017 by Centers for Disease Control and Prevention (CDC).   Date Released: 7/6/2017.

  3. Vitality at work and its associations with lifestyle, self-determination, organizational culture, and with employees' performance and sustainable employability

    NARCIS (Netherlands)

    van Scheppingen, A.R.; de Vroome, E.M.M.; ten Have, K.C.J.M.; Zwetsloot, G.I.J.M.; Wiezer, N.; van Mechelen, W.

    2015-01-01

    BACKGROUND: Vitality at work is an important factor for optimal functioning and sustainable employability. To date, knowledge on how to promote vitality at work is fragmented. OBJECTIVE: Contribute to knowledge on how to promote vitality at work. METHODS: Determinants of vitality at work are

  4. Resistive thrust production can be as crucial as added mass mechanisms for inertial undulatory swimmers

    Science.gov (United States)

    Piñeirua, M.; Godoy-Diana, R.; Thiria, B.

    2015-08-01

    In this Rapid Communication, we address a crucial point regarding the description of moderate to high Reynolds numbers aquatic swimmers. For decades, swimming animals have been classified in two different families of propulsive mechanisms based on the Reynolds number: the resistive swimmers, using local friction to produce the necessary thrust force for locomotion at low Reynolds number, and the reactive swimmers, lying in the high Reynolds range, and using added mass acceleration (described by perfect fluid theory). However, inertial swimmers are also systems that dissipate energy, due to their finite size, therefore involving strong resistive contributions, even for high Reynolds numbers. Using a complete model for the hydrodynamic forces, involving both reactive and resistive contributions, we revisit here the physical mechanisms responsible for the thrust production of such swimmers. We show, for instance, that the resistive part of the force balance is as crucial as added mass effects in the modeling of the thrust force, especially for elongated species. The conclusions brought by this work may have significant contributions to the understanding of complex swimming mechanisms, especially for the future design of artificial swimmers.

  5. Through-Wall Multiple Targets Vital Signs Tracking Based on VMD Algorithm

    Directory of Open Access Journals (Sweden)

    Jiaming Yan

    2016-08-01

    Full Text Available Targets located at the same distance are easily neglected in most through-wall multiple targets detecting applications which use the single-input single-output (SISO ultra-wideband (UWB radar system. In this paper, a novel multiple targets vital signs tracking algorithm for through-wall detection using SISO UWB radar has been proposed. Taking advantage of the high-resolution decomposition of the Variational Mode Decomposition (VMD based algorithm, the respiration signals of different targets can be decomposed into different sub-signals, and then, we can track the time-varying respiration signals accurately when human targets located in the same distance. Intensive evaluation has been conducted to show the effectiveness of our scheme with a 0.15 m thick concrete brick wall. Constant, piecewise-constant and time-varying vital signs could be separated and tracked successfully with the proposed VMD based algorithm for two targets, even up to three targets. For the multiple targets’ vital signs tracking issues like urban search and rescue missions, our algorithm has superior capability in most detection applications.

  6. An Approach for Simulation of the Muscle Force Modeling It by Summation of Motor Unit Contraction Forces

    Directory of Open Access Journals (Sweden)

    Rositsa Raikova

    2013-01-01

    Full Text Available Muscle force is due to the cumulative effect of repetitively contracting motor units (MUs. To simulate the contribution of each MU to whole muscle force, an approach implemented in a novel computer program is proposed. The individual contraction of an MU (the twitch is modeled by a 6-parameter analytical function previously proposed; the force of one MU is a sum of its contractions due to an applied stimulation pattern, and the muscle force is the sum of the active MUs. The number of MUs, the number of slow, fast-fatigue-resistant, and fast-fatigable MUs, and their six parameters as well as a file with stimulation patterns for each MU are inputs for the developed software. Different muscles and different firing patterns can be simulated changing the input data. The functionality of the program is illustrated with a model consisting of 30 MUs of rat medial gastrocnemius muscle. The twitches of these MUs were experimentally measured and modeled. The forces of the MUs and of the whole muscle were simulated using different stimulation patterns that included different regular, irregular, synchronous, and asynchronous firing patterns of MUs. The size principle of MUs for recruitment and derecruitment was also demonstrated using different stimulation paradigms.

  7. Herpes viruses, cytokines, and altered hemostasis in vital exhaustion.

    NARCIS (Netherlands)

    Ven, A.J.A.M. van der; Diest, R. van; Hamulyak, K.; Maes, M.; Bruggeman, C.A.; Appels, A.

    2003-01-01

    OBJECTIVE: Infections with herpes viruses have been implicated in the pathogenesis of atherosclerosis. We tested the hypothesis that vital exhaustion (VE) is associated with multiple herpesvirus infections, such as herpes simplex virus, varicella-zoster virus, Epstein-Barr virus, and

  8. Resistance and support to electronic government, building a model of innovation

    NARCIS (Netherlands)

    Ebbers, Wolfgang E.; van Dijk, Johannes A.G.M.

    2007-01-01

    In several countries forces that resist e-government innovations apparently override those that support them. A first step is taken in order to identify organizational processes of resistance and support to e-government innovations. A multi-disciplinary and non-linear innovation model is proposed

  9. Implementing healthcare excellence: the vital role of the CEO in evidence-based design.

    Science.gov (United States)

    Zimring, Craig; Augenbroe, Godfried L; Malone, Eileen B; Sadler, Blair L

    2008-01-01

    This paper explores the role of the chief executive officer (CEO) in evidence-based design (EBD), discussing the internal and external challenges that a CEO faces, such as demands for increased quality, safety, patient-and-family-centeredness, increased revenue, and reduced cost. Based on a series of interviews and case studies and the experience of the authors as researchers, consultants, and CEOs, this paper provides a model for EBD and recommends actions that a CEO can undertake to create an effective project over the life cycle of a building. TOPICAL HEADINGS: Evidence-Based Design: A Performance-Based Approach to Achieving Key Goals; Key Approaches to Executing Evidence-Based Design; Overcoming Barriers to Innovation: The CEO's Vital Role in Implementing Evidence-Based Design The CEO bears special responsibility for successful facility project implementation. Only the CEO possesses the responsibility and authority to articulate the strategy, vision, goals, and resource constraints that frame every project. With the support of their boards, CEOs set the stage for the transformation of an organization's culture and fuel clinical and business process reengineering by encouraging and, if necessary, forcing collaboration between the strong disciplinary and departmental divisions found in healthcare systems.

  10. Driving Forces of Plate Tectonics and Evolution of the Oceanic Lithosphere and Asthenosphere

    Science.gov (United States)

    Forsyth, D. W.

    2017-12-01

    As plate tectonics became established as an excellent kinematic description of the relative motions of different blocks of the Earth's lithosphere, many investigators also began exploring the forces involved in driving the plate motions. Because the plates move at nearly constant velocities over long periods of time and inertial terms are unimportant, driving forces must always be balanced by resisting forces in a way that regulates the velocities. Forsyth and Uyeda (1975) incorporated the balancing of torques on the individual plates to help constrain the relative importance of the driving and resisting forces, as parameterized in a way based on prior model investigations of individual parts of the convecting system. We found that the primary driving force was sinking of subducting lithosphere at trenches, balanced largely by viscous resisting forces in the sub-asthenospheric mantle; that viscous drag beneath the oceanic plates was negligible; and that mid-ocean ridges provided a relatively small push. One of the early questions was whether there was buoyant upwelling on a large scale beneath mid-ocean ridges as part of a whole mantle convection system with subduction of the plates representing the downwelling limb. If so, then it would be likely that the plates were just riding on top of large convection cells. Seismic tomography has demonstrated that, on average, there are no deep roots beneath mid-ocean ridges, so that active, buoyant upwelling from the deep mantle does not exist beneath spreading centers. However, more recent tomographic studies have found asymmetry of the shear velocity structure beneath ridges in some areas, pointing to a smaller scale of active convection in the shallow mantle perhaps induced by melt retention buoyancy or the local effects of ridge/hotspot interaction.

  11. Integration and embedding of vital signs sensors and other devices into textiles

    OpenAIRE

    Abreu, Maria José Araújo Marques; Carvalho, Helder; Catarino, André P.; Rocha, A. M.

    2010-01-01

    The development of ubiquitous vital sign monitoring has become a very up-to-date research theme for many academics and industrial companies in the last years. With new materials and integration techniques, it is possible to implement vital sign monitoring in an economic manner, directly into textile products. This unobtrusive presence of sensors is especially important for the monitoring of children or elderly people. This paper focuses on two aspects of sensor integration: Integration of off...

  12. PIKO-6® vs. forced spirometry in asthmatic children.

    Science.gov (United States)

    Gochicoa-Rangel, Laura; Larios-Castañeda, Pablo José; Miguel-Reyes, José Luis; Briseño, David Martínez; Flores-Campos, Roberto; Sáenz-López, Juan Arturo; Torre-Bouscoulet, Luis

    2014-12-01

    The PIKO-6® is an electronic device that measures forced expiratory volume at seconds 1 (FEV1) and 6 (FEV6) of a forced vital capacity (FVC) maneuver. This device could aid in diagnosing obstructive respiratory diseases. To determine the concordance of FEV1, FEV6, and the FEV1/FEV6 quotient achieved with PIKO-6® versus spirometric values from asthmatic patients, and compare results with measures from healthy children. A cross-sectional study with asthmatic and healthy 6-to-14-year-old children, all of whom performed a forced spirometry as well as a PIKO-6® test. The study included 82 subjects (58 asthmatics, 24 healthy children). Except for the functional parameters, the basal characteristics of the two groups were similar. The concordance correlation coefficient (CCC) for FEV1 was 0.938 (P spirometry was lower in patients with partially controlled or uncontrolled asthma compared to controlled or healthy children. The broad limits of agreement show that the FEV1, FEV6, and FEV1/FEV6 obtained with the PIKO-6® are not interchangeable with spirometry results. Longitudinal evaluations of asthma patients are necessary to assess the utility of PIKO-6®. © 2014 Wiley Periodicals, Inc.

  13. Subjective Vitality and Patterns of Acculturation: Four Cases

    Science.gov (United States)

    Ehala, Martin; Vedernikova, Elena

    2015-01-01

    The article presents a comparative analysis of the subjective vitalities (SVs) of the minority groups of Latvia (Russian-speakers), Lithuania (Russian-speakers and Poles) and Mari El (Maris) in the Russian Federation, with a particular focus on the Mari case. The same extended version of the SV questionnaire was used in quantitative surveys in all…

  14. Ten Indicators of Vitality in Smaller Academic Libraries

    Science.gov (United States)

    Pappas, David

    2009-01-01

    This paper provides a means of quickly ascertaining the relative health of smaller academic libraries by presenting a top ten list of vitality indicators. The list is based on an observational convenience sampling of thirty smaller academic libraries across the United States. The indicators making the list were those which appeared most often in…

  15. Modelling the clamping force distribution among chips in press-pack IGBTs using the finite element method

    DEFF Research Database (Denmark)

    Hasmasan, Adrian Augustin; Busca, Christian; Teodorescu, Remus

    2012-01-01

    In this paper, a FEM (finite element method) based mechanical model for PP (press-pack) IGBTs (insulated gate bipolar transistors) is presented, which can be used to calculate the clamping force distribution among chips under various clamping conditions. The clamping force is an important parameter...... for the chip, because it influences contact electrical resistance, contact thermal resistance and power cycling capability. Ideally, the clamping force should be equally distributed among chips, in order to maximize the reliability of the PP IGBT. The model is built around a hypothetical PP IGBT with 9 chips......, and it has numerous simplifications in order to reduce the simulation time as much as possible. The developed model is used to analyze the clamping force distribution among chips, in various study cases, where uniform and non-uniform clamping pressures are applied on the studied PP IGBT....

  16. Conducting atomic force microscopy studies on doped CulnO2 thin films for resistive memory device applications

    International Nuclear Information System (INIS)

    Mehta, B.R.

    2009-01-01

    Full text: Delafosite thin films have interesting structural, optical and electronic properties due to the highly anisotropic crystal structure and possibility of bipolar conductivity. In this presentation, optical, structural and electrical properties of Sn (n type) and Ca (p type) doped CulnO 2 layers grown by rf magnetron sputtering technique will be discussed. Depending on doping and deposition temperature, these films show nanocolumnar structure with (110) and (006) preferred orientations. The observed decrease in activation energy from 0.9 eV to about 0.10 eV and a large decrease in conductivity from 2.11 x 10 -10 Scm -1 to 1.66 x 10 -1 Scm -1 on Sn doping has been explained due to the change in preferred orientation along with efficient doping. Our results show that crystallite orientation is the most important factor controlling the electrical conduction in delafossite thin films. The anisotropy of electrical conduction along (006) and (110) directions in tin doped samples has been further established using conducting atomic force microscopy (CAFM) measurements. The CAFM measurements shows the presence of nanoconducting region when the current flow direction is aligned along the BO 6 layer and complete absence of conducting regions when the current direction is perpendicular to the film surface. Resistive memory devices based on Sn and Ca doped CulnO 2 films show stable and reproducible 'on' and 'off' states. CAFM measurement on these devices carried out before and after 'forming' show the growth of nanoconducting filaments on the application of a threshold voltage. It is possible to control resistance in the 'on' and 'off' states and magnitude of the forming and switching voltages by controlling the doping concentration and crystallite orientation in CulnO 2 layers

  17. Nursing assessment of continuous vital sign surveillance to improve patient safety on the medical/surgical unit.

    Science.gov (United States)

    Watkins, Terri; Whisman, Lynn; Booker, Pamela

    2016-01-01

    Evaluate continuous vital sign surveillance as a tool to improve patient safety in the medical/surgical unit. Failure-to-rescue is an important measure of hospital quality. Patient deterioration is often preceded by changes in vital signs. However, continuous multi-parameter vital sign monitoring may decrease patient safety with an abundance of unnecessary alarms. Prospective observational study at two geographically disperse hospitals in a single hospital system. A multi-parameter vital sign monitoring system was installed in a medical/surgical unit in Utah and one in Alabama providing continuous display of SpO2, heart rate, blood pressure and respiration rate on a central station. Alarm thresholds and time to alert annunciations were set based on prior analysis of the distribution of each vital sign. At the end of 4 weeks, nurses completed a survey on their experience. An average alert per patient, per day was determined retrospectively from the saved vital signs data and knowledge of the alarm settings. Ninety-two per cent of the nurses agreed that the number of alarms and alerts were appropriate; 54% strongly agreed. On average, both units experienced 10·8 alarms per patient, per day. One hundred per cent agreed the monitor provided valuable patient data that increased patient safety; 79% strongly agreed. Continuous, multi-parameter patient monitoring could be performed on medical/surgical units with a small and appropriate level of alarms. Continuous vital sign assessment may have initiated nursing interventions that prevented failure-to-rescue events. Nurses surveyed unanimously agreed that continuous vital sign surveillance will help enhance patient safety. Nursing response to abnormal vital signs is one of the most important levers in patient safety, by providing timely recognition of early clinical deterioration. This occurs through diligent nursing surveillance, involving assessment, interpretation of data, recognition of a problem and meaningful

  18. LongoVital i forebyggelsen af recidiverende aftøs stomatit. 1

    DEFF Research Database (Denmark)

    Pedersen, A; Hougen, H P; Klausen, B

    1991-01-01

    LongoVital (LV) (DK. reg. no. 5178/75) is a herbal based tablet enriched with recommended doses of vitamins. The present study was undertaken to investigate prevention of recurrent aphthous ulceration (RAU) during daily intake of LV for six months as compared with placebo in a double-blind, rando......LongoVital (LV) (DK. reg. no. 5178/75) is a herbal based tablet enriched with recommended doses of vitamins. The present study was undertaken to investigate prevention of recurrent aphthous ulceration (RAU) during daily intake of LV for six months as compared with placebo in a double...

  19. Research on micromanipulator’s clamping force sensing based on static wirerope tension of a surgical robot

    Directory of Open Access Journals (Sweden)

    Lingtao Yu

    2015-04-01

    Full Text Available The micromanipulator’s force feedback is one of the key research contents of minimally invasive surgical robotic system. Because the micromanipulator is a kind of compact construction which is suitable for valve installation with small space in surgery, especially for the influence of disinfection method, there are major difficulties and limitations to integrate compact sensors in the end of micromanipulator. This article focuses on the 3-degree-of-freedom micromanipulator’s clamping force sensing, and these three joints are actuated by wirerope driving. A clamping force sensing method is proposed based on static tension of wirerope driving, and a static model between the clamping force and wirerope’s static tension is established considering the influence of real friction resistance in the mechanical system. Finally, an equivalent experimental test platform for 3-degree-of-freedom micromanipulator’s clamping force sensing is set up, and then a series of experiments of the clamping force are studied. The frictional resistances of wirerope between the guide plate and guide pulley mechanism are tested, and a calibration and correction method of the experimental clamping force is proposed. The final experiment results show that the total average accuracy of experimental clamping force is about 78.3%, and it can be the basic measurement force to realize micromanipulator’s clamping force feedback of a minimally invasive surgical robot.

  20. Loss of Olfactory Function and Nutritional Status in Vital Older Adults and Geriatric Patients

    NARCIS (Netherlands)

    Toussaint, N.; Roon, de M.; Campen, van J.P.C.M.; Kremer, S.; Boesveldt, S.

    2015-01-01

    The aim of this cross-sectional study was to assess the association of olfactory function and nutritional status in vital older adults and geriatric patients. Three hundred forty-five vital (mean age 67.1 years) and 138 geriatric older adults (mean age 80.9 years) were included. Nutritional status

  1. Associations between VO2max and vitality in older workers: A cross-sectional study

    NARCIS (Netherlands)

    Strijk, J.E.; Proper, K.I.; Klaver, L.; Beek, A.J. van der; Mechelen, W. van

    2010-01-01

    Background. To prevent early exit from work, it is important to study which factors contribute to healthy ageing. One concept that is assumed to be closely related to, and therefore may influence healthy ageing, is vitality. Vitality consists of both a mental and a physical component, and is

  2. Vital Signs-Preventing Pregnancy in Younger Teens

    Centers for Disease Control (CDC) Podcasts

    2014-04-08

    This podcast is based on the April 2014 CDC Vital Signs report. Births to teens are declining, still, in 2012, more than 86,000 teens ages 15 to 17 gave birth. This program discusses what health care providers, parents, and teens can do to help prevent teen pregnancy.  Created: 4/8/2014 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/8/2014.

  3. Pain and fear avoidance partially mediate change in muscle strength during resistance exercise in women with fibromyalgia.

    Science.gov (United States)

    Larsson, Anette; Palstam, Annie; Löfgren, Monika; Ernberg, Malin; Bjersing, Jan; Bileviciute-Ljungar, Indre; Gerdle, Björn; Kosek, Eva; Mannerkorpi, Kaisa

    2017-11-21

    Resistance exercise results in health benefits in fibromyalgia. The aim of this study was to determine the factors that mediate change in muscle strength in women with fibromyalgia as a result of resistance exercise. Sixty-seven women with fibromyalgia (age range 25-64 years) were included. Tests of muscle strength and questionnaires related to pain, fear avoidance and physical activity were carried out. Multivariable stepwise regression was used to analyse explanatory factors for change and predictors for final values of knee-extension force, elbow-flexion force and hand-grip force. Change in knee-extension force was explained by fear avoidance beliefs about physical activity at baseline, together with change in pain intensity, knee-extension force at baseline, age and body mass index (BMI) (R2=0.40, p = 0.013). Change in elbow-flexion force was explained by pain intensity at baseline, together with baseline fear avoidance beliefs about physical activity, BMI and elbow-flexion force at baseline (R2 = 0.32, p = 0.043). Change in hand-grip force was explained by hand-grip force at baseline, change in pain intensity and baseline fear avoidance (R2 = 0.37, p = 0.009). Final muscle strength was predicted by the same variables as change, except pain. Pain and fear avoidance are important factors to consider in rehabilitation using resistance exercise for women with fibromyalgia.

  4. Vital Signs-Children Need More Fruits and Vegetables!

    Centers for Disease Control (CDC) Podcasts

    2014-08-05

    This podcast is based on the August 2014 CDC Vital Signs report. Children in the U.S. aren't eating enough fruits and vegetables. Learn what you can do to impact this problem.  Created: 8/5/2014 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 8/5/2014.

  5. DETERMINATION OF THE ISSUE CONCERNING THE LIFT RESISTANCE FACTOR OF LIGHTWEIGHT CAR

    Directory of Open Access Journals (Sweden)

    A. O. Shvets

    2015-10-01

    Full Text Available Purpose. The analytical study of the connection between the longitudinal force, acting on the light-weight car, lateral and vertical forces of interaction in the contact zone «wheel – rail» with the lift resistance factor value is to provide a simple relationships between them. Methodology. Research was conducted by the method of mathematical modeling of loading the freight car when driving at different speeds on straight and curved sections of a track. Findings. Even in the absence of «lift» accordingly the classical train stability theory, as the hinge-rod system, the presence of the longitudinal compressive forces may become a factor provoking cars derailment. The main reason of wheel climbing on rails is the combination of processes of dynamic interaction between the hunting vehicle and the track with simultaneous action of longitudinal compressive forces, and not the destabilization of train as a hingedrod system. To assess the impact of the longitudinal forces value on the lift resistance factor there are presented the calculation results for the empty gondola car motion, model No. 12-532, on 250 m radius curve with 150 mm rise and cross starting of car underframe relating to the track axis in 50 mm guiding section. The calculations were made in such a curve excluding the inertial forces from outstanding acceleration and taking into account the unbalanced acceleration with the permissible speed of 65 km/h. Originality. This study provides the technique of determining the lift resistance factor by longitudinal forces, which is somewhat different from the standard one, as well as evaluates impact of rolling stock speed on this factor. Practical value. The authors clarify the current method of determining the lift resistance factor by longitudinal forces and assess the impact of rolling stock speed on the value of this factor. From these studies one can conclude that because of cars hunting their lift is possible even when the train as

  6. Predicting subjective vitality and performance in sports: the role of passion and achievement goals.

    Science.gov (United States)

    Li, Chiung-Huang

    2010-06-01

    The major purpose of this study was to test the hypothesized paths from dualistic passions through achievement goals to subjective vitality and performance in sports. 645 high school athletes participated. The proposed structural equation model, with relationships between dualistic passions and subjective vitality and sports performance mediated by achievement goals, fit the data well, especially for mastery-approach and performance-approach goals. Harmonious and obsessive passions may lead athletes to high performance via the adoption of mastery-approach goals. However, these passions seem to have two paths influencing personal functioning: direct effects make players feel energetic, and indirect effects on subjective vitality through adoption of mastery-approach and performance-approach goals.

  7. The Relationship between Faculty Involvement in Governance and Faculty Vitality: The Case of North Carolina Community Colleges

    Science.gov (United States)

    Madray, Van

    2009-01-01

    This study examines the effects of governance involvement on the vitality of community college faculty members. This study explores the degree to which involvement in the governance of a college through a faculty senate fosters the vitality of elected faculty members. While faculty vitality is a difficult concept to measure directly, faculty…

  8. Signos Vitales de los CDC Cómo prevenir los brotes de norovirus (Vital Signs-Preventing Norovirus Outbreaks)

    Centers for Disease Control (CDC) Podcasts

    2014-06-03

    Este podcast se basa en la edición de junio del 2014 del informe Signos Vitales de los CDC. Los norovirus infectan cada año a cerca de 20 millones de personas en los Estados Unidos. Sepa cómo protegerse y proteger a su familia de esta enfermedad que es muy contagiosa y potencialmente grave.  Created: 6/3/2014 by National Center for Immunization and Respiratory Diseases (NCIRD).   Date Released: 6/3/2014.

  9. Unification of Forces: The Road to Jointness?

    Science.gov (United States)

    1991-05-15

    tend to resist large change--or innovation. Because organizations value "predictability, stability, and certainty," incremental change is the...preferred mode of behavior for organizations.29 Unification of the forces would be a large, rather than an incremental , change; thus, the services would...coordinating planning and bidgeting , providing unified direction, accounting and controlling weapons and equipment acquisition, eliminating duplication of

  10. The economic role of the Emergency Department in the health care continuum: applying Michael Porter's five forces model to Emergency Medicine.

    Science.gov (United States)

    Pines, Jesse M

    2006-05-01

    Emergency Medicine plays a vital role in the health care continuum in the United States. Michael Porters' five forces model of industry analysis provides an insight into the economics of emergency care by showing how the forces of supplier power, buyer power, threat of substitution, barriers to entry, and internal rivalry affect Emergency Medicine. Illustrating these relationships provides a view into the complexities of the emergency care industry and offers opportunities for Emergency Departments, groups of physicians, and the individual emergency physician to maximize the relationship with other market players.

  11. Examining the Relationship between Self-rumination and Happiness: The Mediating and Moderating Role of Subjective Vitality

    OpenAIRE

    SARIÇAM, Hakan

    2016-01-01

    The basic purpose of this study is to examine the mediating and moderating role of subjective vitality in relationship between rumination and subjective happiness. The participants were 420 university students. In this research, the Self-rumination Scale-SRS, the Subjective Vitality Scale and the Short Form of Oxford Happiness Questionnaire were used. The relationships between rumination, subjective vitality, and happiness were examined using correlation analysis and hierarchical regression a...

  12. A new biomedical device for in vivo multiparametric evaluation of tissue vitality in critical care medicine

    Science.gov (United States)

    Mayevsky, Avraham; Deutsch, Assaf; Dekel, Nava; Pevzner, Eliyahu; Jaronkin, Alex

    2005-04-01

    Real time Monitoring of mitochondrial function in vivo is a significant factor in the understanding of tissue vitality. Nevertheless a single parameter monitoring device is not appropriate and effective in clinical diagnosis of tissue vitality. Therefore we have developed a multi-parametric monitoring system that monitors, in addition to mitochondrial NADH redox state, tissue microcirculatory blood flow, tissue total back-scattered light as an indication of blood volume and blood oxygenation (Hb02). In the present communication a new device named "CritiView" is described. This device was developed in order to enable real time monitoring of the four parameters from various organs in the body. The main medical application of the CritiView is in critical care medicine of patients hospitalized in the Intensive Care Units (ICUs) and intraoperatively in operating rooms. The physiological basis for our clinical monitoring approach is based on the well known response to the development of body emergency situation, such as shock or trauma. Under such conditions a process of blood flow redistribution will give preference to vital organs (Brain, Heart) neglecting less vital organs (Skin, G-I tract or the urinary system). Under such condition the brain will by hyperperfused and O2 supply will increase to provide the need of the activated mitochondria. The non-vital organs will be hypoperfused and mitochondial function will be inhibited leading to energy failure. This differentiation between the two types of organs could be used for the early detection of body deterioration by monitoring of the non-vital organ vitality. A fiber optic sensor was embedded in a Foley catheter, enabling the monitoring of Urethral wall vitality, to serve as an early warning signal of body deterioration.

  13. Resistivity imaging of Aluto-Langano geothermal field using 3-D magnetotelluric inversion

    Science.gov (United States)

    Cherkose, Biruk Abera; Mizunaga, Hideki

    2018-03-01

    Magnetotelluric (MT) method is a widely used geophysical method in geothermal exploration. It is used to image subsurface resistivity structures from shallow depths up to several kilometers of depth. Resistivity imaging using MT method in high-enthalpy geothermal systems is an effective tool to identify conductive clay layers that cover the geothermal systems and to detect a potential reservoir. A resistivity model is vital for deciding the location of pilot and production sites at the early stages of a geothermal project. In this study, a 3-D resistivity model of Aluto-Langano geothermal field was constructed to map structures related to a geothermal resource. The inversion program, ModEM was used to recover the 3-D resistivity model of the study area. The 3-D inversion result revealed the three main resistivity structures: a high-resistivity surface layer related to unaltered volcanic rocks at shallow depth, underlain by a conductive zone associated with the presence of conductive clay minerals, predominantly smectite. Beneath the conductive layer, the resistivity increases gradually to higher values related to the formation of high-temperature alteration minerals such as chlorite and epidote. The resistivity model recovered from 3-D inversion in Aluto-Langano corresponds very well to the conceptual model for high-enthalpy volcanic geothermal systems. The conductive clay cap is overlying the resistive propylitic upflow zone as confirmed by the geothermal wells in the area.

  14. Effectiveness of a Multilevel Workplace Health Promotion Program on Vitality, Health, and Work-Related Outcomes.

    Science.gov (United States)

    Hendriksen, Ingrid J M; Snoijer, Mirjam; de Kok, Brenda P H; van Vilsteren, Jeroen; Hofstetter, Hedwig

    2016-06-01

    Evaluation of the effectiveness of a workplace health promotion program on employees' vitality, health, and work-related outcomes, and exploring the influence of organizational support and the supervisors' role on these outcomes. The 5-month intervention included activities at management, team, and individual level targeting self-management to perform healthy behaviors: a kick-off session, vitality training sessions, workshops, individual coaching, and intervision. Outcome measures were collected using questionnaires, health checks, and sickness absence data at baseline, after the intervention and at 10 months follow-up. For analysis linear and generalized mixed models were used. Vitality, work performance, sickness absence, and self-management significantly improved. Good organizational support and involved supervisors were significantly associated with lower sickness absence. Including all organizational levels and focusing on increasing self-management provided promising results for improving vitality, health, and work-related outcomes.

  15. An experimental vital signs detection radar using low-IF heterodyne architecture and single-sideband transmission

    DEFF Research Database (Denmark)

    Jensen, Brian Sveistrup; Johansen, Tom Keinicke; Yan, Lei

    2013-01-01

    In this paper an experimental X-band radar system, called DTU-VISDAM, developed for the detection and monitoring of human vital signs is described. The DTU-VISDAM radar exploits a low intermediate frequency (IF) heterodyne RF front-end architecture and single-sideband (SSB) transmission for easier...... and more reliable extraction of the vital signs. The hardware implementation of the proposed low-IF RF front-end architecture and associated IF circuitry is discussed. Furthermore, the signal processing and calibration steps necessary to extract the vital signs information measured on a human subject...

  16. Determination of ductile tearing resistance J-R curves in welded joints; Determination de courbes de resistance a la dechirure ductile dans les joints soudes

    Energy Technology Data Exchange (ETDEWEB)

    Gilles, Ph.; Ould, P. [AREVA NP, Tour AREVA, 92086 Paris La Defense (France); Marie, St. [CEA Saclay, DM2S, 91191 Gif sur Yvette Cedex (France)

    2010-05-15

    The ductile tearing resistance of steels is generally characterized in terms of resistance curves giving the increase of a resistance parameter such as the crack driving force J or a crack opening displacement as a function of the crack extension {Delta}a. Welded joints are often the weakest part of structures because of greater risk of defects, heterogeneity of the microstructure of the weld, strain concentration along mismatched interfaces. This paper recalls the transferability issues common to all integrity assessments based on tearing resistance curves and points out the difficulties of characterization specific to welds. Several recommendations are proposed for the experimental determination of tearing resistance of welded joints. (authors)

  17. Hydrogeological characterisation using cross-borehole ground penetration radar and electrical resistivity tomography

    DEFF Research Database (Denmark)

    Zibar, Majken Caroline Looms

    2007-01-01

    was characterized by ~30 m thick unsaturated zone consisting mainly of sands of varying coarseness. Following an instrumentation of 16 boreholes two geophysical methods (cross-borehole ground penetrating radar and electrical resistivity tomography) were applied during natural precipitation and forced infiltration...... properties of the subsurface. On the other hand, volumetric moisture content variations of up to 5% were observed during a 20-day long forced infiltration experiment. The cross-borehole electrical resistance tomography and ground penetrating radar data collected during this experiment were subsequently....... The methods provided estimates of soil moisture content and electrical resistivity variations among 12 m deep boreholes located 5 – 7 m apart. The moisture content change following natural precipitation was observed to be practically negligible, providing minimal information to constrain the dynamic...

  18. The wheat homolog of putative nucleotide-binding site-leucine-rich repeat resistance gene TaRGA contributes to resistance against powdery mildew.

    Science.gov (United States)

    Wang, Defu; Wang, Xiaobing; Mei, Yu; Dong, Hansong

    2016-03-01

    Powdery mildew, one of the most destructive wheat diseases worldwide, is caused by Blumeria graminis f. sp. tritici (Bgt), a fungal species with a consistently high mutation rate that makes individual resistance (R) genes ineffective. Therefore, effective resistance-related gene cloning is vital for breeding and studying the resistance mechanisms of the disease. In this study, a putative nucleotide-binding site-leucine-rich repeat (NBS-LRR) R gene (TaRGA) was cloned using a homology-based cloning strategy and analyzed for its effect on powdery mildew disease and wheat defense responses. Real-time reverse transcription-PCR (RT-PCR) analyses revealed that a Bgt isolate 15 and salicylic acid stimulation significantly induced TaRGA in the resistant variety. Furthermore, the silencing of TaRGA in powdery mildew-resistant plants increased susceptibility to Bgt15 and prompted conidia propagation at the infection site. However, the expression of TaRGA in leaf segments after single-cell transient expression assay highly increased the defense responses to Bgt15 by enhancing callose deposition and phenolic autofluorogen accumulation at the pathogen invading sites. Meanwhile, the expression of pathogenesis-related genes decreased in the TaRGA-silenced plants and increased in the TaRGA-transient-overexpressing leaf segments. These results implied that the TaRGA gene positively regulates the defense response to powdery mildew disease in wheat.

  19. The nature and extent of police use of force in encounters with people with behavioral health disorders.

    Science.gov (United States)

    Morabito, Melissa S; Socia, Kelly; Wik, Amanda; Fisher, William H

    Previous research studies have examined the treatment of people with mental illnesses by the police. Much available data support the adoption of the Crisis Intervention Team (CIT) model. A key issue in CIT development has been reduction in the use of force by CIT officers, and it is suggested that such adoption does accomplish such reduction. However, to date, scant research compares variation in police use of force by CIT officers across populations with mental illnesses, co-occurring disorders, and substance abuse disorders, as compared to their non-disordered peers. Using data from the Portland Police Bureau, a police agency in which all patrol officers have been trained in the CIT model, we analyze whether police use-of-force differs across these groups. Police use-of-force data were collected for 4211 incidents from the Portland Police Bureau from 2008 to 2011. Results indicate that people perceived as having comorbid behavioral health disorders were generally more likely to have force used against them, and more likely to be perceived as resistant, than people that were perceived as having only substance use disorder, only mental health disorders, or no apparent behavioral health disorders. People with co-occurring disorders are more likely to be perceived as violently resisting police officers and have force used against them. Further, people with no perceived disorders are more likely to have a firearm pointed at them in use-of-force encounters, but also the least likely to be perceived as resisting. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Vital Signs – When Food Bites Back

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the June 2013 CDC Vital Signs report. It discusses food poisoning and specifically, Listeria. If you're 65 or older, have a weakened immune system, or are pregnant, you must be especially careful when selecting, preparing, and storing food.

  1. In Search of Vitality

    DEFF Research Database (Denmark)

    Jørgensen, Jens Lohfert; Ebbesen Nielsen, Louise

    2010-01-01

    This article draws attention to the paradigmatic shift in the use of the concept of ‘life’, which can be observed at the end of the nineteenth century. With Michel Foucault’s notion of bio-power as a foil, the article aims firstly to discuss how influential aesthetic, biological and political...... concepts such as vitalism (Hans Driesch) and degeneration (Max Nordau) can be conceived as different reactions to Charles Darwin’s On the Origin of the Species in the light of bio-power. Even though both Driesch and Nordau use Darwin’s theories to produce positive ideas about respectively the strong...... and healthy body and the strong and healthy society, it is important to note that they do not converge. Secondly, the article aims to discuss how a controversy between these concepts is given literary form in the Danish author Herman Bang’s novel Hopeless Generations (1880), perceived as one of the first...

  2. La teoria del ciclo vitale del risparmio di Modigliani cinquant’anni dopo

    Directory of Open Access Journals (Sweden)

    Mauro Baranzini

    2012-04-01

    Full Text Available In the early 50s Franco Modigliani and Richard Brumberg and Albert Ando, ​​formulated the life-cycle theory of consumption and saving, which has been a huge success and undisputed for at least three decades. However, since the early 80s the life-cycle theory has been criticized in an increasingly tight for at least four reasons. The first is the existence of a significant intergenerational transmission of wealth, due to factors exogenous to the model of the life cycle. The second reason is the increasing evidence that the rich continue to save a greater extent than the less fortunate, as, in fact, Keynes argued. The third reason is that there is increasing evidence, at least in Western Europe and Japan, young families, during twenty and thirty years of age, save a positive and growing share of their income, which arises in decided contrast to the original version of the life-cycle theory. Finally, a number of empirical studies have found that retirees dismiss a high proportion of their income. This requires a serious rethinking of the approach of the life-cycle theory, which affects both the economic analysis and economic policy. Nei primi anni ’50 Franco Modigliani, insieme a Richard Brumberg e ad Albert Ando, formulò la teoria del ciclo vitale del consumo e del risparmio, che ha riscosso un enorme e indiscusso successo per almeno tre decenni. Tuttavia, a partire dai primi anni ’80 la teoria del ciclo vitale è stata criticata in modo sempre più serrato, per almeno quattro ragioni. La prima consiste nell’esistenza di una significativa trasmissione intergenerazionale della ricchezza, da ricondurre a cause esogene al modello del ciclo vitale. La seconda ragione è rappresentata dalla crescente evidenza che i ricchi continuano a risparmiare in misura maggiore rispetto ai meno fortunati, come, in effetti, Keynes sosteneva. Il terzo motivo è che vi sono prove sempre più evidenti, almeno nell’Europa occidentale e in Giappone

  3. National Vital Statistics System (NVSS) - National Cardiovascular Disease Surveillance Data

    Data.gov (United States)

    U.S. Department of Health & Human Services — 2000 forward. NVSS is a secure, web-based data management system that collects and disseminates the Nation's official vital statistics. Indicators from this data...

  4. Sistema de gestión estadística: Hechos vitales e identificados

    OpenAIRE

    Díaz Echenique, Melchor Angel; Díaz Echenique, Melchor Angel; Díaz Echenique, Melchor Angel

    2011-01-01

    La presente Tesis para optar el grado de Magíster en Ciencias con mención en Ingeniería de Sistemas se titula: "SISTEMA DE GESTION ESTADISTICA: HECHOS VITALES E IDENTIFICACION". El Problema, en el que se centra la presente tesis, exige responder a la interrogante: ¿Se presentan o producen empirismos normativos, incumplimientos, deficiencias y restricciones en el Sistema de Gestión Estadística: ¿Hechos Vitales e Identificación? El Problema tiene 4 partes con las siguientes prioridad...

  5. CDC Vital Signs–HIV Testing

    Centers for Disease Control (CDC) Podcasts

    2017-11-28

    This podcast is based on the December 2017 CDC Vital Signs report. In the U.S., about 15 percent of people who have HIV don't know they have it. Learn about the importance of testing, early diagnosis, and treatment.  Created: 11/28/2017 by Centers for Disease Control and Prevention (CDC).   Date Released: 11/28/2017.

  6. Vital Signs – Prescription Painkiller Overdoses

    Centers for Disease Control (CDC) Podcasts

    2013-07-02

    This podcast is based on the July 2013 CDC Vital Signs report. Prescription painkiller overdoses are an under-recognized and growing problem among women. This program includes things that women and health care providers can do to reduce the risk of overdose.  Created: 7/2/2013 by Centers for Disease Control and Prevention (CDC).   Date Released: 7/2/2013.

  7. Vital Signs – Defeating Breast Cancer

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the November 2012 CDC Vital Signs report. Breast cancer is the second leading cause of cancer deaths among women in the United States. Better screening and treatment have contributed to a decline in breast cancer deaths, however, not all women have benefited equally from these improvements. Learn how we can all help reduce deaths from breast cancer.

  8. The Relationship between Test Anxiety and Academic Performance of Students in Vital Statistics Course

    Directory of Open Access Journals (Sweden)

    Shirin Iranfar

    2013-12-01

    Full Text Available Introduction: Test anxiety is a common phenomenon among students and is one of the problems of educational system. The present study was conducted to investigate the test anxiety in vital statistics course and its association with academic performance of students at Kermanshah University of Medical Sciences. This study was descriptive-analytical and the study sample included the students studying in nursing and midwifery, paramedicine and health faculties that had taken vital statistics course and were selected through census method. Sarason questionnaire was used to analyze the test anxiety. Data were analyzed by descriptive and inferential statistics. The findings indicated no significant correlation between test anxiety and score of vital statistics course.

  9. Timing and extent of finger force enslaving during a dynamic force task cannot be explained by EMG activity patterns.

    Directory of Open Access Journals (Sweden)

    Mojtaba Mirakhorlo

    Full Text Available Finger enslaving is defined as the inability of the fingers to move or to produce force independently. Such finger enslaving has predominantly been investigated for isometric force tasks. The aim of this study was to assess whether the extent of force enslaving is dependent on relative finger movements. Ten right-handed subjects (22-30 years flexed the index finger while counteracting constant resistance forces (4, 6 and 8 N orthogonal to the fingertip. The other, non-instructed fingers were held in extension. EMG activities of the mm. flexor digitorum superficialis (FDS and extensor digitorum (ED in the regions corresponding to the index, middle and ring fingers were measured. Forces exerted by the non-instructed fingers increased substantially (by 0.2 to 1.4 N with flexion of the index finger, increasing the enslaving effect with respect to the static, pre-movement phase. Such changes in force were found 260-370 ms after the initiation of index flexion. The estimated MCP joint angle of the index finger at which forces exerted by the non-instructed fingers started to increase varied between 4° and 6°. In contrast to the finger forces, no significant changes in EMG activity of the FDS regions corresponding to the non-instructed fingers upon index finger flexion were found. This mismatch between forces and EMG of the non-instructed fingers, as well as the delay in force development are in agreement with connective tissue linkages being slack when the positions of the fingers are similar, but pulled taut when one finger moves relative to the others. Although neural factors cannot be excluded, our results suggest that mechanical connections between muscle-tendon structures were (at least partly responsible for the observed increase in force enslaving during index finger flexion.

  10. Scintigraphic test of the vitality and functional fitness of organs conserved for transplantation

    International Nuclear Information System (INIS)

    Bozduganov, A.; Marinov, V.

    1976-01-01

    Having reviewed critically present-day methods of testing the vitality of isolated perfused organs, the authors propose their own. It is founded in the principles of colour scintigraphy after introduction of short-lived nuclides. The method was applied in testing 57 isolated preserved organs (5 kidneys, 12 livers, 5 hearts and 4 spleens from dogs; 2 kidneys and 27 livers from rabbits; 1 kidney and 1 liver from young pigs). Moreover, compararive scintigraphic and biochemical investigations were conducted on 2 dogs and 4 young pigs (A. Bozduganov, E. Simeonov, N. Bogdanova). The techniques of isolation and perfusion of the organ have been given a detailed description. Sup(113m)In was used as tracer. Areas of radioactivity deposits were visualized more or less intensely, depending on the degree of vitality and functional fitness still present actually; else, blanks were seen. Orthotransplantation and heterotransplantation with subsequent scintigraphic examination in vivo served, in scattered instances, the purpose of confirming or of rejecting ambiguous vitality findings in preserved organs. Advantages of the method are a general and specified evaluation of the organ in all of its areas; anatomical integrity of the object under test; applicability to various organs; possibility of conducting dynamic tests; accurate reproduction of vitality and functional findings, etc

  11. Bleaching in vital deciduous teeth – a clinical case

    Directory of Open Access Journals (Sweden)

    José Carlos Pettorossi Imparato

    2008-01-01

    Full Text Available There has been growing concern and search for esthetic beauty and harmony over the last few years. This concern does not form part ofadults’ lives only, but also of children’s. Among the substances used for bleaching dental structures, the most outstanding are those whoseactive principle is hydrogen peroxide-based . The present study reports a clinical case of a 4-year-old girl that suffered trauma of tooth 61 with consequent color alteration, but with no alteration in pulp vitality. The main complaint by the patient and her guardians concerned esthetics, therefore external dental bleaching was performed, using Opalescence Xtra® (Ultradent, in two sessions with an interval of one month between them. External in office bleaching was the treatment of choice, due to the tooth vitality, patient’s age and presence of only one darkened tooth. After the bleaching treatments an improvement in the darkening was observed, and both the child and her guardians were satisfied with the esthetic result.

  12. CDC Signos Vitales: Enfermedad del legionario (CDC Vital Signs–Legionnaires’ Disease)

    Centers for Disease Control (CDC) Podcasts

    2016-06-07

    Este podcast se basa en la edición de junio del 2016 del informe Signos Vitales de los CDC. Las personas pueden contraer la enfermedad del legionario, un tipo grave de infección pulmonar, al inhalar pequeñas gotitas de agua contaminada con bacterias Legionella. Obtenga más información sobre lo que se puede hacer para ayudar a prevenir brotes de enfermedad del legionario y mantener seguras a las personas.  Created: 6/7/2016 by National Center for Immunization and Respiratory Diseases (NCIRD).   Date Released: 6/7/2016.

  13. L’ipotesi del ciclo vitale, la politica fiscale e la previdenza sociale

    Directory of Open Access Journals (Sweden)

    Tullio Jappelli

    2005-06-01

    Full Text Available Il lavoro riassume le principali implicazioni dell’ipotesi del ciclo vitale per quanto riguarda il risparmio individuale e aggregato, la politica fiscale e la previdenza sociale, soffermandosi sui contributi più importanti di Modigliani su questi temi. Anche se non è facile conciliare alcuni risultati empirici recenti con l’ipotesi del ciclo vitale, soprattutto gli aspetti di inerzia, miopia e comportamento irrazionale documentati nella letteratura comportamentale, gli studi di Modigliani rappresentano ancora oggi la base di riferimento principale per studiare le decisioni dirisparmio individuali e per operare scelte di politica economica.

  14. Resistive foil edge grading for accelerator and other high voltage structures

    Science.gov (United States)

    Caporaso, George J.; Sampayan, Stephen F.; Sanders, David M.

    2014-06-10

    In a structure or device having a pair of electrical conductors separated by an insulator across which a voltage is placed, resistive layers are formed around the conductors to force the electric potential within the insulator to distribute more uniformly so as to decrease or eliminate electric field enhancement at the conductor edges. This is done by utilizing the properties of resistive layers to allow the voltage on the electrode to diffuse outwards, reducing the field stress at the conductor edge. Preferably, the resistive layer has a tapered resistivity, with a lower resistivity adjacent to the conductor and a higher resistivity away from the conductor. Generally, a resistive path across the insulator is provided, preferably by providing a resistive region in the bulk of the insulator, with the resistive layer extending over the resistive region.

  15. Technical evaluation report on the 120 Vac vital instrument buses and inverter Technical Specifications Issue B71

    International Nuclear Information System (INIS)

    St Leger-Barter, G.; White, R.L.

    1982-01-01

    The operation of a Pressurized Water Reactor (PWR) with one of its 120 Vac vital buses energized in an off-normal mode was analyzed. A Probabilistic Risk Assessment was made to determine the increment of risk by energizing a vital bus from an off-site source directly vs energizing it from its normal, uninterruptible source (i.e., a battery/inverter arrangement). The calculations were made based on uninterruptible source energized vital buses as the normal mode. The analysis indicated that a reduction in the incremental risk increase (caused by plant operation with a vital bus being energized in an off-normal mode) can be accomplished by limiting the time permitted in that condition. Currently, the time that a vital bus can be energized in the off-normal mode is not universally time-limited by plant Technical Specifications. Several alternatives for the reduction in incremental risk were examined and their value/impacts were derived. These data indicate that a recommendation be made for a Technical Specification time limitation of 72 hours per year for off-normal energizing a vital bus during operation of a PWR

  16. Hysteresis Compensation of Piezoresistive Carbon Nanotube/Polydimethylsiloxane Composite-Based Force Sensors

    Directory of Open Access Journals (Sweden)

    Ji-Sik Kim

    2017-01-01

    Full Text Available This paper provides a preliminary study on the hysteresis compensation of a piezoresistive silicon-based polymer composite, poly(dimethylsiloxane dispersed with carbon nanotubes (CNTs, to demonstrate its feasibility as a conductive composite (i.e., a force-sensitive resistor for force sensors. In this study, the potential use of the nanotube/polydimethylsiloxane (CNT/PDMS as a force sensor is evaluated for the first time. The experimental results show that the electrical resistance of the CNT/PDMS composite changes in response to sinusoidal loading and static compressive load. The compensated output based on the Duhem hysteresis model shows a linear relationship. This simple hysteresis model can compensate for the nonlinear frequency-dependent hysteresis phenomenon when a dynamic sinusoidal force input is applied.

  17. A risk-based approach to designing effective security force training exercises

    International Nuclear Information System (INIS)

    Bott, T.F.; Eisenhawer, S.W.

    2002-01-01

    The effectiveness of a security force in protecting a nuclear facility is often evaluated using training exercises that pit a group of simulated attackers against a security team. In the situation studied here, a security force was regularly tested by a regulatory body with the responsibility for security oversight. It was observed that the regulators were continually imposing more challenging security scenarios by assigning increasingly sophisticated facility knowledge to the attackers. Not surprisingly, the security forces' assessed effectiveness decreased until eventually they were unable to successfully resist the attacks. Security managers maintained that the knowledge attributed to the attackers was becoming increasingly unrealistic and feared they would be forced to concentrate resources on unrealistic scenarios at the expense of more credible threats.

  18. Magnetic property effect on transport processes in resistance spot welding

    Energy Technology Data Exchange (ETDEWEB)

    Wei, P S [Department of Mechanical and Electro-Mechanical Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan 80424 (China); Wu, T H, E-mail: pswei@mail.nsysu.edu.tw, E-mail: wux0064@gmail.com [Department of Mechanical Engineering, Yung Ta Institute of Technology and Commerce, Pintong, Taiwan 909 (China)

    2011-08-17

    This study investigates the effects of the Curie temperature and magnetic permeability on transport variables, solute distribution and nugget shapes during resistance spot welding. The Curie temperature is the temperature below which a metal or alloy is ferromagnetic with a high magnetic permeability, and above which it is paramagnetic with a small magnetic permeability. The model proposed here accounts for electromagnetic force, heat generation and contact resistance at the faying surface and electrode-workpiece interfaces and bulk resistance in workpieces. Contact resistance includes constriction and film resistances, which are functions of hardness, temperature, electrode force and surface condition. The computed results show that transport variables and nugget shapes can be consistently interpreted from the delay of response time and jump of electric current density as a result of finite magnetic diffusion, rather than through the examination of the variations of dynamic electrical resistance with time. The molten nugget on the faying surface is initiated earlier with increasing magnetic permeability and Curie temperature. A high Curie temperature enhances convection and solute mixing, and readily melts through the workpiece surface near the electrode edge. Any means to reduce the Curie temperature or magnetic permeability, such as adjusting the solute content, can be a good way to control weld quality. This study can also be applied to interpret the contact problems encountered in various electronics and packaging technologies, and so on.

  19. Interrupted orthodontic force results in less root resorption than continuous force in human premolars as measured by microcomputed tomography.

    Science.gov (United States)

    Sawicka, Monika; Bedini, Rossella; Wierzbicki, Piotr M; Pameijer, Cornelis H

    2014-01-01

    Root resorption is an undesirable but very frequently occurring sequel of orthodontic treatment. The aim of this study was to compare root resorption caused by either continuous (CF) or interrupted (IF) orthodontic force. The study was performed on human subjects on 30 first upper and lower premolars scheduled for extraction for orthodontic reasons. During four weeks before extraction 12 teeth were subjected to either CF or IF. The force was generated by a segmental titanium-molybdenum alloy cantilever spring that was activated in buccal direction. Initially a force of 60 CentiNewton was used in both CF and IF groups, the force in the former, however, was reactivated every week for 4 weeks. There was no reactivation of force in the IF group after initial application. A morphometric analysis of root resorption was performed by microcomputed tomography and the extent of tooth movement was measured on stone casts. Furthermore, a Tartarate-Resistant Acidic Phosphatase activity (TRAP), the marker enzyme of osteoclasts and cementoclasts, was determined by histochemical method. The Mann-Whitney U test was used to compare the difference in measured parameters between treatment and control tooth groups. The number of resorption craters was significantly higher and their average volume almost twice as large in the CF compared to the IF group (p root structure as opposed to continuous force while the same tooth movement was achieved.

  20. LongoVital in the prevention of recurrent aphthous ulceration

    DEFF Research Database (Denmark)

    Pedersen, A; Hougen, H P; Klausen, B

    1990-01-01

    LongoVital (LV) (DK. Reg. No. 5178/75) is a herbal based tablet enriched with recommended doses of vitamins. The present study was undertaken to investigate prevention of recurrent aphthous ulceration (RAU) during 6 months' daily intake of LV as compared with placebo in a double-blind, randomized...

  1. Quantitative estimation of electro-osmosis force on charged particles inside a borosilicate resistive-pulse sensor.

    Science.gov (United States)

    Ghobadi, Mostafa; Yuqian Zhang; Rana, Ankit; Esfahani, Ehsan T; Esfandiari, Leyla

    2016-08-01

    Nano and micron-scale pore sensors have been widely used for biomolecular sensing application due to its sensitive, label-free and potentially cost-effective criteria. Electrophoretic and electroosmosis are major forces which play significant roles on the sensor's performance. In this work, we have developed a mathematical model based on experimental and simulation results of negatively charged particles passing through a 2μm diameter solid-state borosilicate pore under a constant applied electric field. The mathematical model has estimated the ratio of electroosmosis force to electrophoretic force on particles to be 77.5%.

  2. Force Curves to Demonstrate Methods to Increase Musculoskeletal Loading with the ARED

    Data.gov (United States)

    National Aeronautics and Space Administration — Current resistance exercises on ISS do not meet the requirements set by expert panels in that the eccentric loads are less than concentric loads, forces are variable...

  3. Subjective Vitality as Mediator and Moderator of the Relationship between Life Satisfaction and Subjective Happiness

    Science.gov (United States)

    Uysal, Recep; Satici, Seydi Ahmet; Satici, Begüm; Akin, Ahmet

    2014-01-01

    In this study, the mediator and moderator effects of subjective vitality on the relationship between life satisfaction and subjective happiness were investigated. The participants were 378 university students who completed a questionnaire package that included the Subjective Vitality Scale, the Satisfaction with Life Scale, and the Subjective…

  4. Oxidative stress resistance in Porphyromonas gingivalis

    Science.gov (United States)

    Henry, Leroy G; McKenzie, Rachelle ME; Robles, Antonette; Fletcher, Hansel M

    2012-01-01

    Porphyromonas gingivalis, a black-pigmented, Gram-negative anaerobe, is an important etiologic agent of periodontal disease. The harsh inflammatory condition of the periodontal pocket implies that this organism has properties that will facilitate its ability to respond and adapt to oxidative stress. Because the stress response in the pathogen is a major determinant of its virulence, a comprehensive understanding of its oxidative stress resistance strategy is vital. We discuss multiple mechanisms and systems that clearly work in synergy to defend and protect P. gingivalis against oxidative damage caused by reactive oxygen species. The involvement of multiple hypothetical proteins and/or proteins of unknown function in this process may imply other unique mechanisms and potential therapeutic targets. PMID:22439726

  5. Effect of intrusive and retraction forces in labial and lingual orthodontics: A finite element study

    Directory of Open Access Journals (Sweden)

    Rohan Mascarenhas

    2014-01-01

    Full Text Available Objectives: Lingual orthodontics differs in biomechanics as compared to labial system and has biomechanical advantages. Although theoretical approaches have explained the differences between labial and lingual orthodontics, the finite element method (FEM may be better suited to analyze these differences. This study analyzes the effect of vertical and horizontal forces together on the tooth using FEM. Materials and Methods: An extracted right maxillary central incisor was radiographed and was used to create a solid model using ANSYS. The geometric model was converted into a finite element model with the help of ANSYS software. The model consists of 27,000 elements and 30,000 nodes. Two force vectors (vertical and horizontal were applied labially and lingually at 3 different heights- 4 mm, 5 mm and 6 mm from the incisal edge. Results: In the labial system, the net force vector passes through the center of resistance (CR and brings about intrusion. The net force vector in lingual orthodontics does not pass through the center of resistance and produces lingual tipping of the incisors. Conclusion: Intrusion and retraction forces bring about tipping of incisors in lingual orthodontics. The same amount of intrusion and retraction forces brings about intrusion of incisors in labial orthodontics. Therefore, direction and amount of forces should be carefully and judiciously applied after taking into consideration the resultant biomechanical differences.

  6. Vital Signs-Physical Activity and Adults with Disabilities

    Centers for Disease Control (CDC) Podcasts

    2014-05-06

    This podcast is based on the May 2014 CDC Vital Signs report. Adults with disabilities who get no aerobic physical activity are 50 percent more likely to have heart disease, stroke, diabetes, or cancer. Learn what you can do to help.  Created: 5/6/2014 by National Center on Birth Defects and Developmental Disabilities (NCBDDD).   Date Released: 5/6/2014.

  7. Single-limb force data for two lemur species while vertically clinging.

    Science.gov (United States)

    Johnson, Laura E; Hanna, Jandy; Schmitt, Daniel

    2015-11-01

    Vertical clinging and climbing have been integral to hypotheses about primate origins, yet little is known about how an animal with nails instead of claws resists gravity while on large, vertical, and cylindrical substrates. Here we test models of how force is applied to maintain posture, predicting (1) the shear component force (Fs ) at the hands will be higher than the feet; (2) the normal component force (Fn ) at the feet will be relatively high compared to the hands; (3) the component force resisting gravity (Fg ) at the feet will be relatively high compared to the hands; (4) species with a high frequency of vertical clinging postures will have low Fg at the hands due to relatively short forelimbs. Using a novel instrumented support, single-limb force data were collected during clinging postures for the hands and feet and compared across limbs and species for Propithecus verreauxi (N = 2), a habitual vertical clinger and leaper, and Varecia variegata (N = 3), a habitual above-branch arboreal quadruped. For both species, hand Fs were significantly higher than at the feet and Fn and Fg at the feet were significantly higher than at the hands. Between species, P. verreauxi has relatively low Fg at the hands and Fn at the feet than V. vareigata. These results support previous models and show that hindlimb loading dominance, characteristic of primate locomotion, is found during clinging behaviors and may allow the forelimbs to be used for foraging while clinging. These findings provide insight into selective pressures on force distribution in primates and primate locomotor evolution. © 2015 Wiley Periodicals, Inc.

  8. Anomalous feedback and negative domain wall resistance

    International Nuclear Information System (INIS)

    Cheng, Ran; Xiao, Di; Zhu, Jian-Gang

    2016-01-01

    Magnetic induction can be regarded as a negative feedback effect, where the motive-force opposes the change of magnetic flux that generates the motive-force. In artificial electromagnetics emerging from spintronics, however, this is not necessarily the case. By studying the current-induced domain wall dynamics in a cylindrical nanowire, we show that the spin motive-force exerting on electrons can either oppose or support the applied current that drives the domain wall. The switching into the anomalous feedback regime occurs when the strength of the dissipative torque β is about twice the value of the Gilbert damping constant α . The anomalous feedback manifests as a negative domain wall resistance, which has an analogy with the water turbine. (paper)

  9. Algorithmic tools for interpreting vital signs.

    Science.gov (United States)

    Rathbun, Melina C; Ruth-Sahd, Lisa A

    2009-07-01

    Today's complex world of nursing practice challenges nurse educators to develop teaching methods that promote critical thinking skills and foster quick problem solving in the novice nurse. Traditional pedagogies previously used in the classroom and clinical setting are no longer adequate to prepare nursing students for entry into practice. In addition, educators have expressed frustration when encouraging students to apply newly learned theoretical content to direct the care of assigned patients in the clinical setting. This article presents algorithms as an innovative teaching strategy to guide novice student nurses in the interpretation and decision making related to vital sign assessment in an acute care setting.

  10. Forced-Air Warming Provides Better Control of Body Temperature in Porcine Surgical Patients

    Directory of Open Access Journals (Sweden)

    Brian T. Dent

    2016-09-01

    Full Text Available Background: Maintaining normothermia during porcine surgery is critical in ensuring subject welfare and recovery, reducing the risk of immune system compromise and surgical-site infection that can result from hypothermia. In humans, various methods of patient heating have been demonstrated to be useful, but less evaluation has been performed in techniques to prevent hypothermia perioperatively in pigs. Methods: We compared body temperature regulation during surgery before and after modification of the ambient temperature of the operating laboratories. Three different methods of heating were then compared; a standard circulating water mattress, a resistive fabric blanket, and a forced hot air system. The primary measure was percentage of temperature readings outside a specification range of 36.7–40.0 °C. Results: Tighter control of the ambient temperature while using a circulating water mattress reduced the occurrence of out-of-specification body temperature readings from 20.8% to 5.0%, with most of these the result of hypothermia. Use of a resistive fabric blanket further reduced out-of-specification readings to 1.5%, with a slight increase in the occurrence of hyperthermia. Use of a forced air system reduced out-of-specification readings to less 0.1%. Conclusions: Maintenance of normothermia perioperatively in pig can be improved by tightly controlling ambient temperatures. Use of a resistive blanket or a forced air system can lead to better control than a circulating water mattress, with the forced air system providing a faster response to temperature variations and less chance of hyperthermia.

  11. The Role of Tree Mortality in Vitality Assessment of Sessile Oak Forests

    Directory of Open Access Journals (Sweden)

    Imre Berki

    2016-12-01

    Full Text Available Background and Purpose: The drought-induced vitality loss of sessile oak (Quercus petraea (Matt. Liebl. has been continuously observed in Hungary for more than three decades. The decrease in stand density as a consequence of drought-induced mortality has not been taken into consideration in most of the monitoring methods. Materials and Methods: Forest stands without any forest intervention during the last 30 years were selected. Quadrats were designated for the analysis in 18 sessile oak stands along a climatic transect in which foliage transparency and stand density were measured. Drought stress was defined by the water balance approach. By combining the foliage transparency and the relative stand density, a new cumulative assessment method of stand level vitality was introduced to get a more realistic picture about the effects of long-term drought (lasting for several decades on the sessile oak forests in South-East Europe. Results: The calculated health status (100% - vital; 0% - dead of the sessile oak stands was between 70-90% in the moist South-West Hungary and below 50% close to its xeric limit. The individual tree-based vitality assessment method gave considerably higher values on 17 out of 18 sites. Conclusions: Forest monitoring should also consider stand level-based tree mortality in oak forests while assessing health condition especially close to its xeric limit. The proposed new method provides a more realistic picture about the effects of climate change on sessile oak stands particularly for forest managers interested in changing in the wood stock of forests.

  12. VIPEX (Vital-area Identification Package EXpert) Software Verification and Validation

    International Nuclear Information System (INIS)

    Jung, Woo Sik; Suh, Jae Seung

    2010-06-01

    The purposes of this report are (1) to perform a Verification and Validation (V and V) test for the VIPEX(Vital-area Identification Package EXpert) software and (2) to improve a software quality through the V and V test. The VIPEX was developed in Korea Atomic Energy Research Institute (KAERI) for the Vital Area Identification (VAI) of nuclear power plants. The version of the VIPEX which was distributed is 3.2.0.0. The VIPEX was revised based on the first V and V test and the second V and V test was performed. We have performed the following tasks for the V and V test on Windows XP and VISTA operating systems: Ο Testing basic functions including fault tree editing Ο Testing all kind of functions Ο Research for update from Visual BASIC 6.0 to Visual BASIC 2008

  13. Freeing France: The Allies, the Resistance, and the JEDBURGHs

    National Research Council Canada - National Science Library

    Jones, Benjamin F

    2008-01-01

    .... The study below examines the Allied politics, the nature and the development of the French Resistance, and the actions of the German forces in France to evaluate how useful the deployment of 93...

  14. Global Current Circuit Structure in a Resistive Pulsar Magnetosphere Model

    Science.gov (United States)

    Kato, Yugo. E.

    2017-12-01

    Pulsar magnetospheres have strong magnetic fields and large amounts of plasma. The structures of these magnetospheres are studied using force-free electrodynamics. To understand pulsar magnetospheres, discussions must include their outer region. However, force-free electrodynamics is limited in it does not handle dissipation. Therefore, a resistive pulsar magnetic field model is needed. To break the ideal magnetohydrodynamic (MHD) condition E\\cdot B=0, Ohm’s law is used. This work introduces resistivity depending upon the distance from the star and obtain a self-consistent steady state by time integration. Poloidal current circuits form in the magnetosphere while the toroidal magnetic field region expands beyond the light cylinder and the Poynting flux radiation appears. High electric resistivity causes a large space scale poloidal current circuit and the magnetosphere radiates a larger Poynting flux than the linear increase outside of the light cylinder radius. The formed poloidal-current circuit has width, which grows with the electric conductivity. This result contributes to a more concrete dissipative pulsar magnetosphere model.

  15. Glucometabolic effects of single and repeated exposure to forced-swimming stressor in Sprague-Dawley rats.

    Science.gov (United States)

    Morakinyo, Ayodele Olufemi; Iranloye, Bolanle Olubusola; Ogunsola, Oluseyi Abimbola

    2018-04-01

    We aimed to evaluate the effects of a single (acute) and repeated (chronic) exposure to forced-swimming stressor on glucose tolerance, insulin sensitivity, lipid profile and glycogen content in male rats. Thirty adult male Sprague-Dawley rats (12 weeks old) were divided randomly into five groups: control group, single exposure (SE) to forced-swim stressor, repeated exposure to forced-swim stressor for 7 days (RE7), 14 days (RE14) and 28 days (RE28). Glucose tolerance test and Homeostatic Model Assessment-Insulin Resistance (HOMA-IR) were undertaken on fasting rats to obtain glucose and insulin profiles. ELISA was performed to assess plasma insulin and corticosterone levels. Total cholesterol, triglyceride, high- and low-density lipoproteins, hepatic and skeletal glycogen content were also determined. Repeated exposure to stressor induced glucose intolerance and insulin resistance in the experimental rats. Results showed that all RE groups exhibited a significantly higher area under the curve compared with others (p=0.0001); similarly, HOMA-IR increased (p=0.0001) in all RE groups compared with control. Prolonged exposure to stressor significantly increased the plasma insulin and corticosterone levels but decreased the glycogen content in the liver and skeletal muscle when compared with the control group. Additionally, chronic stressor significantly increased the total cholesterol and triglyceride levels, however, acute stressor produced significantly elevated high-density lipoproteins level. In conclusion, repeated exposure to forced-swimming stressor induced glucose intolerance and insulin resistance in rats by disrupting the insulin sensitivity as well as heightening the glycogenolysis in the liver and skeletal muscle. Acute stressor was unable to cause glucose intolerance and insulin resistance but it appears that may have a positive effect on the lipid metabolism.

  16. Mid-Career Faculty Development in Academic Medicine: How Does It Impact Faculty and Institutional Vitality?

    Science.gov (United States)

    Campion, MaryAnn W.; Bhasin, Robina M.; Beaudette, Donald J.; Shann, Mary H.; Benjamin, Emelia J.

    2016-01-01

    Purpose: Faculty vitality is integral to the advancement of higher education. Strengthening vitality is particularly important for midcareer faculty, who represent the largest and most dissatisfied segment. The demands of academic medicine appear to be another factor that may put faculty at risk of attrition. To address these issues, we initiated…

  17. Anaesthetic indices and vital parameters of PPR-infected West ...

    African Journals Online (AJOL)

    The aim of this study, was to assess and compare the anaesthetic indices and vital parameters of West African Dwarf (WAD) goats naturally infected with PPR before and after epidural anaesthesia with plain lignocaine and also to compare the measured anaesthetic indices with those of healthy goats. Ten goats were used ...

  18. Vital Signs – Preventing Repeat Teen Births

    Centers for Disease Control (CDC) Podcasts

    2013-04-02

    This podcast is based on the April 2013 CDC Vital Signs report, which discusses repeat teen births and ways teens, parents and guardians, health care providers, and communities can help prevent them.  Created: 4/2/2013 by Centers for Disease Control and Prevention (CDC).   Date Released: 4/2/2013.

  19. Trusted Care In The Air Force Medical Service: Practical Recommendations For Transformation

    Science.gov (United States)

    2016-02-16

    in the U.S. Air Force Dental Corps. As a dental officer, he completed his residency in periodontics in 2006 at The University of Texas Health...Force Academy, followed by a position on the teaching staff at the periodontics residency at Joint Base San Antonio-Lackland. Prior to his current...military organization may be fully on board with changes in policy and/or transformation, the process for getting rid of those who are chronic resisters

  20. Force modulation and electrochemical gating of conductance in a cytochrome

    Science.gov (United States)

    Davis, Jason J.; Peters, Ben; Xi, Wang

    2008-09-01

    Scanning probe methods have been used to measure the effect of electrochemical potential and applied force on the tunnelling conductance of the redox metalloprotein yeast iso-1-cytochrome c (YCC) at a molecular level. The interaction of a proximal probe with any sample under test will, at this scale, be inherently perturbative. This is demonstrated with conductive probe atomic force microscopy (CP-AFM) current-voltage spectroscopy in which YCC, chemically adsorbed onto pristine Au(111) via its surface cysteine residue, is observed to become increasingly compressed as applied load is increased, with concomitant decrease in junction resistance. Electrical contact at minimal perturbation, where probe-molecule coupling is comparable to that in scanning tunnelling microscopy, brings with it the observation of negative differential resistance, assigned to redox-assisted probe-substrate tunnelling. The role of the redox centre in conductance is also resolved in electrochemical scanning tunnelling microscopy assays where molecular conductance is electrochemically gateable through more than an order of magnitude.

  1. Is Demography Destiny? Urban Population Change and Economic Vitality of Future Cities

    Directory of Open Access Journals (Sweden)

    Jacques Poot

    Full Text Available ABSTRACT: The growth of cities has attracted considerable scholarly attention during the last decade as it is becoming clear that powerful agglomeration forces are reinforcing the role of cities as the engines of economic growth. Close to 4 billion people live in cities, about 55 per cent of the world's population. While population growth rates are declining and the world's population is likely to level off from the middle of the 21st century, probably ending up around 10 billion, further urbanization is expected to continue. Another 3 billion people will become urban citizens this century. At the same time no corner of the world will be sheltered from sweeping demographic changes due to population ageing and increasing migration. Such changes will be amplified in cities. In this paper we combine UN population projections and migration data with our own assumptions to derive projections of age composition and birthplace composition of urban populations by continent. We also briefly address the consequences of these demographic trends for future urban economic vitality. Particular attention is paid to the impacts of demographic changes on urban creativity and innovation. We conclude that, with the right policies in place, such demographic changes enhance rather than impede the future prosperity of the urban world. KEYWORDS: World population projections, urbanization, ageing, migration, ethnic diversity

  2. Psicología del ciclo vital: hacia una visión comprehensiva de la vida humana

    OpenAIRE

    Elisa Dulcey Ruiz; Cecilia Uribe Valdivieso

    2002-01-01

    Se propone que la psicología del ciclo vital es más amplia que la psicología del desarrollo. Coherente con una visión integral del curso del ciclo vital esta psicología enfatiza la irrelevancia de la edad, los cambios permanentes, la multidimensionalidad, y la plasticidad, también como la importancia del contexto y la historia. Se refiere al proceso de envejecimiento, a la adultez, la vejez y la muerte en el marco del ciclo vital; enfatiza posibilidades relacionadas con el envejecimiento exit...

  3. Psicología del ciclo vital: hacia una visión comprehensiva de la vida humana

    OpenAIRE

    Elisa Dulcey Ruiz; Cecilia Uribe Valdivieso

    2002-01-01

    Se propone que la psicología del ciclo vital es más amplia que la psicología del desarrollo. Coherente con una visión integral del curso del ciclo vital esta psicología enfatiza la irrelevancia de la edad, los cambios permanentes, la multidimensionalidad, y la plasticidad, también como la importancia del contexto y la historia. Se refiere al proceso de envejecimiento, a la adultez, la vejez y la muerte en el marco del ciclo vital; enfatiza posibilidades relacionadas con el enve...

  4. LQR pitch control strategy of AUVs based on the optimum of sailing resistance

    Directory of Open Access Journals (Sweden)

    YAO Xuliang

    2017-05-01

    Full Text Available When an Autonomous Underwater Vehicle(AUV sails near the surface of the sea,it will inevitably be subjected to wave disturbance. The heave and pitch motion caused by wave disturbance not only affects the navigation attitude of the AUV,but also leads to an increase in sailing resistance. As such, its energy consumption is increased. In this paper,the six degrees of freedom model of AUVs is established and linearized in order to achieve the weighted optimization of the sailing attitude and the resistance of the AUVs. The drag force model of the AUV is derived using the theory of potential flow. The Q matrix and R matrix are determined in the controller based on research into the drag force model. The Linear Quadratic Regulator(LQRcontroller of the AUV is designed using the drag force model as the performance index. The simulation results show that after adding the LQR controller,the effects of reducing heave motion and pitch motion are 46.64% and 77.62% respectively, and the increased resistance caused by the pitch motion is reduced to 1/6 of its original value. The results show that the multiple optimum of attitude and sailing resistance is realized,the energy consumption is decreased and the endurance of the AUV is increased.

  5. Noise considerations for vital signs CW radar sensors

    DEFF Research Database (Denmark)

    Jensen, Brian Sveistrup; Jensen, Thomas; Zhurbenko, Vitaliy

    2011-01-01

    and the underlying signal theory for such sensors. Then to point out and especially clarify one of the most important effects aiding the design of vital signs radars (VSR), a more detailed discussion concerning phase noise cancellation (or filtering) by range correlation is given. This discussion leads to some...... general conclusions about which system components are the most critical concerning noise contribution and thus detection accuracy and dynamic range....

  6. Effect of implanted doses of N+-ions on the contact resistance of copper contacts

    International Nuclear Information System (INIS)

    Dubravec, B.; Kovac, P.; Lipka, F.; Padysak, M.

    1997-01-01

    The paper deals with the effect of implanted doses of N + ions on the contact resistance. Dependencies of the contact resistance versus contact force R c =f(F c ) and microhardness of implanted surfaces were measured for three implanted profiles. The influence of the aggressive environs on the contact resistance of implanted contact is given too

  7. The clinical consequences of antimicrobial resistance.

    Science.gov (United States)

    Rice, Louis B

    2009-10-01

    The continued evolution of antimicrobial resistance in the hospital and more recently in the community threatens to seriously compromise our ability to treat serious infections. The major success of the seven-valent Streptococcus pneumoniae vaccine at reducing both infection and resistance has been followed by the emergence of previously minor serotypes that express multiresistance. The almost universal activity of cephalosporins and fluoroquinolones against community Escherichia coli strains has been compromised by the spread of CTX-M beta-lactamase-producing, fluoroquinolone-resistant strains, and the emergence of community-onset methicillin-resistant Staphylococcus aureus, particularly in the United States, has forced us to re-think our empirical treatment guidelines for skin and soft-tissue infections. Finally, our most potent and reliable class of antibiotics, the carbapenems, is compromised by the growth, primarily in intensive care units, of multiresistant Klebsiella pneumoniae, Acinetobacter baumanni, and Pseudomonas aeruginosa. The lack of a robust pipeline of new agents, particularly against resistant Gram-negative bacteria, emphasizes the importance of optimizing our use of current antimicrobials and promoting strict adherence to established infection control practices.

  8. Bio-inspired ciliary force sensor for robotic platforms

    KAUST Repository

    Ribeiro, Pedro; Khan, Mohammed Asadullah; Alfadhel, Ahmed; Kosel, Jü rgen; Franco, Fernando; Cardoso, Susana; Bernardino, Alexandre; Schmitz, Alexander; Santos-Victor, Jose; Jamone, Lorenzo

    2017-01-01

    The detection of small forces is of great interest in any robotic application that involves interaction with the environment (e.g., objects manipulation, physical human-robot interaction, minimally invasive surgery), since it allows the robot to detect the contacts early on and to act accordingly. In this letter, we present a sensor design inspired by the ciliary structure frequently found in nature, consisting of an array of permanently magnetized cylinders (cilia) patterned over a giant magnetoresistance sensor (GMR). When these cylinders are deformed in shape due to applied forces, the stray magnetic field variation will change the GMR sensor resistivity, thus enabling the electrical measurement of the applied force. In this letter, we present two 3 mm × 3 mm prototypes composed of an array of five cilia with 1 mm of height and 120 and 200 μm of diameter for each prototype. A minimum force of 333 μN was measured. A simulation model for determining the magnetized cylinders average stray magnetic field is also presented.

  9. Bio-inspired ciliary force sensor for robotic platforms

    KAUST Repository

    Ribeiro, Pedro

    2017-01-20

    The detection of small forces is of great interest in any robotic application that involves interaction with the environment (e.g., objects manipulation, physical human-robot interaction, minimally invasive surgery), since it allows the robot to detect the contacts early on and to act accordingly. In this letter, we present a sensor design inspired by the ciliary structure frequently found in nature, consisting of an array of permanently magnetized cylinders (cilia) patterned over a giant magnetoresistance sensor (GMR). When these cylinders are deformed in shape due to applied forces, the stray magnetic field variation will change the GMR sensor resistivity, thus enabling the electrical measurement of the applied force. In this letter, we present two 3 mm × 3 mm prototypes composed of an array of five cilia with 1 mm of height and 120 and 200 μm of diameter for each prototype. A minimum force of 333 μN was measured. A simulation model for determining the magnetized cylinders average stray magnetic field is also presented.

  10. Evaluation of Electrostatic Force on Bipolar Charged Electret

    International Nuclear Information System (INIS)

    Sonoda, K; Minami, K; Miwatani, N; Fujita, T; Kanda, K; Maenaka, K

    2014-01-01

    This paper presents an evaluation of an electrostatic vibration energy harvester with the bipolar charged electret. The energy harvester with the size of 13 × 12 × 1.2 mm 3 was fabricated. The output power of the bipolar charged with ±250 V harvester was 9 μW when the acceleration was 1.4 g at 352 Hz with 0.9 MΩ load resistance. The effectiveness against the velocity-damped resonant-generator (VDRG) limit was 2.5%. The electrostatic forces of the actual device with DC bias, which simulates charged electret with monopolar and bipolar were experimentally and numerically verified. We estimated the electrostatic force by measuring the vibration amplitude versus applied acceleration of the electret mass. As a result, we investigated the bipolar charged device can reduce the effect of electrostatic force as low as no bias condition. The numerical model of the energy harvester considering the electrostatic force by FEM static analysis was also established. The comparison between the numerical model and the measurement results showed a similar inclination

  11. Activity of siderophores against drug-resistant Gram-positive and Gram-negative bacteria

    Directory of Open Access Journals (Sweden)

    Gokarn K

    2018-01-01

    Full Text Available Karuna Gokarn,1,2 Ramprasad B Pal1 1Department of Microbiology, Sir Hurkisondas Nurrotumdas Medical Research Society, 2Caius Research Laboratory, St Xavier’s College, Mumbai, India Abstract: Infections by drug-resistant bacteria are life-threatening. As iron is a vital element for the growth of bacteria, iron-chelating agents (siderophores can be used to arrest their multiplication. Exogenous siderophores – exochelin-MS and deferoxamine-B – were evaluated for their inhibitory activity against methicillin-resistant Staphylococcus aureus and metallo-β-lactamase producers – Pseudomonas aeruginosa and Acinetobacter baumannii – by disc diffusion, micro-broth dilution, and turbidimetric growth assays. The drug-resistant isolates were inhibited by the synergistic activity of siderophores and antibiotics. Minimum inhibitory concentration of exochelin-MS+ampicillin for different isolates was between 0.05 and 0.5 mg/mL. Minimum inhibitory concentration of deferoxamine-B+ampicillin was 1.0 mg/mL and greater. Iron-chelation therapy could provide a complementary approach to overcome drug resistance in pathogenic bacteria. Keywords: iron-chelation, xenosiderophores, exochelin MS, deferoxamine B

  12. Vital area identification software VIP for the physical protection of nuclear power plants

    International Nuclear Information System (INIS)

    Jung, Woo Sik; Park, Chang Kue; Yang, Joon Eon

    2004-01-01

    There are two major factors to be considered for the physical protection of nuclear power plants. They are a design basis threat (DBT) and the vital area identification (VAI). The DBT has been considered as 'the maximum credible threat.' The vital area is defined as 'an area inside a protected area containing equipment, systems or devices, or nuclear materials, the sabotage of which could directly or indirectly lead to unacceptable radiological consequences.' For the VAI of nuclear power plants, a software VIP (Vital area Identification Package based on PSA method) is being developed. The VIP is based on the current probabilistic safety assessment (PSA) techniques. The PSA method, including internal as well as external events, is known as the most complete and consistent method for identifying various accident sequences that might result in a core melt and radioactive material release to the environment. Thus, the VIP employs a fault tree analysis method in the PSA and utilizes the PSA results

  13. Vital Signs – Alcohol Screening and Counseling?

    Centers for Disease Control (CDC) Podcasts

    2014-01-07

    This podcast is based on the January 2014 CDC Vital Signs report. Millions of Americans drink too much, a dangerous behavior that can lead to serious health problems. Alcohol screening and counseling can help.  Created: 1/7/2014 by Centers for Disease Control and Prevention (CDC).   Date Released: 1/7/2014.

  14. Survival and evolution of a large multidrug resistance plasmid in new clinical bacterial hosts

    DEFF Research Database (Denmark)

    Porse, Andreas; Schønning, Kristian; Munck, Christian

    2016-01-01

    Large conjugative plasmids are important drivers of bacterial evolution and contribute significantly to the dissemination of antibiotic resistance. Although plasmid borne multidrug resistance is recognized as one of the main challenges in modern medicine, the adaptive forces shaping the evolution...

  15. Assumptions and Policy Decisions for Vital Area Identification Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Myungsu; Bae, Yeon-Kyoung; Lee, Youngseung [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    U.S. Nuclear Regulatory Commission and IAEA guidance indicate that certain assumptions and policy questions should be addressed to a Vital Area Identification (VAI) process. Korea Hydro and Nuclear Power conducted a VAI based on current Design Basis Threat and engineering judgement to identify APR1400 vital areas. Some of the assumptions were inherited from Probabilistic Safety Assessment (PSA) as a sabotage logic model was based on PSA logic tree and equipment location data. This paper illustrates some important assumptions and policy decisions for APR1400 VAI analysis. Assumptions and policy decisions could be overlooked at the beginning stage of VAI, however they should be carefully reviewed and discussed among engineers, plant operators, and regulators. Through APR1400 VAI process, some of the policy concerns and assumptions for analysis were applied based on document research and expert panel discussions. It was also found that there are more assumptions to define for further studies for other types of nuclear power plants. One of the assumptions is mission time, which was inherited from PSA.

  16. FM-CW radar sensors for vital signs and motor activity monitoring

    Directory of Open Access Journals (Sweden)

    Octavian Adrian Postolache

    2011-12-01

    Full Text Available The article summarizes on-going research on vital signs and motor activity monitoring based on radar sensors embedded in wheelchairs, walkers and crutches for in home rehabilitation. Embedded sensors, conditioning circuits, real-time platforms that perform data acquisition, auto-identification, primary data processing and data communication contribute to convert daily used objects in home rehabilitation into smart objects that can be accessed by caregivers during the training sessions through human–machine interfaces expressed by the new generation of smart phones or tablet computers running Android OS or iOS operating systems. The system enables the management of patients in home rehabilitation by providing more accurate and up-to-date information using pervasive computing of vital signs and motor activity records.

  17. Adaptive Hierarchical Control for the Muscle Strength Training of Stroke Survivors in Robot-Aided Upper-Limb Rehabilitation

    Directory of Open Access Journals (Sweden)

    Guozheng Xu

    2012-10-01

    Full Text Available Muscle strength training for stroke patients is of vital importance for helping survivors to progressively restore muscle strength and improve the performance of their activities in daily living (ADL. An adaptive hierarchical therapy control framework which integrates the patient's real biomechanical state estimation with task-performance quantitative evaluation is proposed. Firstly, a high-level progressive resistive supervisory controller is designed to determine the resistive force base for each training session based on the patient's online task-performance evaluation. Then, a low-level adaptive resistive force triggered controller is presented to further regulate the interactive resistive force corresponding to the patient's real-time biomechanical state – characterized by the patient's bio-damping and bio-stiffness in the course of one training session, so that the patient is challenged in a moderate but engaging and motivating way. Finally, a therapeutic robot system using a Barrett WAM™ compliant manipulator is set up. We recruited eighteen inpatient and outpatient stroke participants who were randomly allocated in experimental (robot-aided and control (conventional physical therapy groups and enrolled for sixteen weeks of progressive resistance training. The preliminary results show that the proposed therapy control strategies can enhance the recovery of strength and motor control ability.

  18. Imaging and modeling of acute pressure-induced changes of collagen and elastin microarchitectures in pig and human resistance arteries.

    Science.gov (United States)

    Bloksgaard, Maria; Leurgans, Thomas M; Spronck, Bart; Heusinkveld, Maarten H G; Thorsted, Bjarne; Rosenstand, Kristoffer; Nissen, Inger; Hansen, Ulla M; Brewer, Jonathan R; Bagatolli, Luis A; Rasmussen, Lars M; Irmukhamedov, Akhmadjon; Reesink, Koen D; De Mey, Jo G R

    2017-07-01

    The impact of disease-related changes in the extracellular matrix (ECM) on the mechanical properties of human resistance arteries largely remains to be established. Resistance arteries from both pig and human parietal pericardium (PRA) display a different ECM microarchitecture compared with frequently used rodent mesenteric arteries. We hypothesized that the biaxial mechanics of PRA mirror pressure-induced changes in the ECM microarchitecture. This was tested using isolated pig PRA as a model system, integrating vital imaging, pressure myography, and mathematical modeling. Collagenase and elastase digestions were applied to evaluate the load-bearing roles of collagen and elastin, respectively. The incremental elastic modulus linearly related to the straightness of adventitial collagen fibers circumferentially and longitudinally (both R 2 ≥ 0.99), whereas there was a nonlinear relationship to the internal elastic lamina elastin fiber branching angles. Mathematical modeling suggested a collagen recruitment strain (means ± SE) of 1.1 ± 0.2 circumferentially and 0.20 ± 0.01 longitudinally, corresponding to a pressure of ~40 mmHg, a finding supported by the vital imaging. The integrated method was tested on human PRA to confirm its validity. These showed limited circumferential distensibility and elongation and a collagen recruitment strain of 0.8 ± 0.1 circumferentially and 0.06 ± 0.02 longitudinally, reached at a distending pressure below 20 mmHg. This was confirmed by vital imaging showing negligible microarchitectural changes of elastin and collagen upon pressurization. In conclusion, we show here, for the first time in resistance arteries, a quantitative relationship between pressure-induced changes in the extracellular matrix and the arterial wall mechanics. The strength of the integrated methods invites for future detailed studies of microvascular pathologies. NEW & NOTEWORTHY This is the first study to quantitatively relate pressure

  19. Lower periorbital area treatment with Restylane Vital Skinbooster

    Directory of Open Access Journals (Sweden)

    Denis Souto Valente

    2016-09-01

    Full Text Available Facial aging along the periocular area has led to the development of new non-surgical therapies. The lower periorbital area is a vital region for facial rejuvenation and several procedures have been studied to treat it, especially procedures with dermal fillers for volume rebuilding. This manuscript aims to describe a filling technique with hyaluronic acid (HA along the superficial layer of the lower periorbital area, presenting its effectiveness and safety. Our assessment was made by autonomous observers with pictures of before and after treatment, rated from 0 (no enhancement to 100 (maximum enhancement. Patients’ self-assessment was also performed using a visual analog scale (VAS based on a 100-mm ruler affording a 0–100 rating. Thirty patients were enrolled in this study. The autonomous observers’ evaluation presented a 78.4 mean improvement rate. Patients’ self-assessments after the treatment were 0% reporting no improvement, 6.7% mild improvement, 23.3% moderate improvement, 66.7% great improvement, and 3.3% maximum improvement. Restylane Vital Skinbooster infiltration at the lower periorbital area proved to be a safe treatment. The described technique is also simple to execute, has a low rate of complications, and produces a high satisfaction rate.

  20. Vital Signs-HIV Care Saves Lives: Viral Suppression is Key

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the December 2014 CDC Vital Signs report. For people living with HIV, Viral suppression is critical. By getting tested and taking HIV medicines, individuals living with HIV can achieve very low levels of HIV in the body.

  1. Links between Catalan identity and the perception of ethno-linguistic vitality in a sample of university students

    OpenAIRE

    Moisès Esteban; M. Àngels Viladot

    2009-01-01

    This article analyses, on the one hand, the perception of ethno-linguistic vitality in a sample of university students in the province of Girona, and, on the other, links this perceived vitality to the feeling of identity in the group to which they belong. 112 Catalan-speaking students who described themselves as Catalan (Catalan identity) responded to the questionnaire on subjective vitality, in terms of adaptation to Catalan. This instrument assesses the beliefs about one's own group's and ...

  2. Effect of reinforcement on the cutting forces while machining metal matrix composites–An experimental approach

    Directory of Open Access Journals (Sweden)

    Ch. Shoba

    2015-12-01

    Full Text Available Hybrid metal matrix composites are of great interest for researchers in recent years, because of their attractive superior properties over traditional materials and single reinforced composites. The machinabilty of hybrid composites becomes vital for manufacturing industries. The need to study the influence of process parameters on the cutting forces in turning such hybrid composite under dry environment is essentially required. In the present study, the influence of machining parameters, e.g. cutting speed, feed and depth of cut on the cutting force components, namely feed force (Ff, cutting force (Fc, and radial force (Fd has been investigated. Investigations were performed on 0, 2, 4, 6 and 8 wt% Silicon carbide (SiC and rice husk ash (RHA reinforced composite specimens. A comparison was made between the reinforced and unreinforced composites. The results proved that all the cutting force components decrease with the increase in the weight percentage of the reinforcement: this was probably due to the dislocation densities generated from the thermal mismatch between the reinforcement and the matrix. Experimental evidence also showed that built-up edge (BUE is formed during machining of low percentage reinforced composites at high speed and high depth of cut. The formation of BUE was captured by SEM, therefore confirming the result. The decrease of cutting force components with lower cutting speed and higher feed and depth of cut was also highlighted. The related mechanisms are explained and presented.

  3. CDC Vital Signs–Arthritis in America

    Centers for Disease Control (CDC) Podcasts

    2017-03-07

    This podcast is based on the March 2017 CDC Vital Signs report. Many adults in the United States have arthritis. Learn how to reduce the pain of arthritis, as well as manage the condition.  Created: 3/7/2017 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 3/7/2017.

  4. The Peritelini (Coleoptera: Curculionidae, Entiminae of the Vitale collection

    Directory of Open Access Journals (Sweden)

    Cosimo Baviera

    2016-01-01

    Full Text Available The collection of Peritelini (Coleoptera Curculionidae Entiminae currently stored in the Vitale collection of Messina University is an element of great importance for studies of taxonomy and biogeography of these rarely collected weevils. All species are commented in relation to the contributions to this taxonomic group, published on several occasions by the authors.

  5. Role of Social Well-Being and Academic Vitality in Predicting the Academic Motivation in Nursing Students

    Directory of Open Access Journals (Sweden)

    Abbasi M.

    2016-02-01

    Full Text Available Aims: Due to the studentship stressful factors and challenging clinical conditions and internship, the nursing students undergo emotional exhaustion and academic burnout. The outcomes might, also, negatively affect their academic engagement and functions. The aim of this study was to explain the academic motivation of the nursing students based on the social welfare and vitality.  Instrument & Methods: In the correlational study, the nursing students of Arak University of Medical Sciences were studied in the academic year 2014-15. 210 students were selected via available sampling. Data was collected using academic motivation, Kees social welfare, and academic vitality questionnaires. Data was analyzed by SPSS 18 software using Pearson correlation and multivariate regression tests. Findings: The total mean scores of social welfare, academic motivation, and academic vitality were 98.68±13.21, 40.55±5.98, and 18.58±7.58, respectively. There were significant and positive correlations between social welfare and academic motivation (r=0.183; p<0.001 and the subscales including emotional motivation (r=0.103; p<0.048 and cognitive motivation (r=0.154; p<0.003. Due to the lack of any correlation between academic vitality and academic motivation and its sub-scales, the academic vitality could not predict the academic motivation. Nevertheless, the social welfare could predict 33% of the variance of academic motivation. Conclusion: The social welfare plays an important role to determine the academic motivation of nursing students. Nevertheless, academic vitality plays no role. 

  6. EFFECT OF POSTURAL DRAINAGE POSITIONS ON VITAL PARAMETERS IN ASYMPTOMATIC HEALTHY INDIVIDUALS

    Directory of Open Access Journals (Sweden)

    Animesh Hazari

    2017-09-01

    Full Text Available Background: Postural drainage is used exclusively or in combination with other airway clearance techniques in the management of chronic pulmonary diseases. Postural drainage therapy helps to prevent accumulation of secretions in patients who are at high risk for pulmonary complications. It also helps to remove accumulated secretions from the lungs.The role of body positioning on lung function and the clinical implications of postural drainage has been identified in a variety of settings including intensive care units. There is dearth in literature on effects on postural drainage on vital parameters. Thus the objective of the study was to measure the vital parameters at different postural drainage positions in healthy asymptomatic adults. Methods: Twenty healthy subjects participated in the study. The instruments used in the current study included a Pulse oximeter, Sphygmomanometer, Stethoscope, Postural drainage table.The outcome measures of interest were heart rate, respiratoryrate, oxygen saturation, blood pressure and Borg’s scale of rate of perceived exertion. The changes in the vital signs were recorded at different head down titling position of 0°, 15° & 30° in both supine and prone lying positions Results: Statistical significant difference was found for Systolic Blood Pressure in prone lying at different degrees of tilt (p=0.001 and Diastolic Blood Pressure in prone lying (p=0.000. Conclusion: Postural drainage positioning should be given with caution and under proper monitoring as there is a risk of change in the blood pressure even in asymptomatic elderly population. The monitoring of vital signs should be done during the therapy to decrease the risk of complications.

  7. Vital Sign Monitoring and Mobile Phone Usage Detection Using IR-UWB Radar for Intended Use in Car Crash Prevention.

    Science.gov (United States)

    Leem, Seong Kyu; Khan, Faheem; Cho, Sung Ho

    2017-05-30

    In order to avoid car crashes, active safety systems are becoming more and more important. Many crashes are caused due to driver drowsiness or mobile phone usage. Detecting the drowsiness of the driver is very important for the safety of a car. Monitoring of vital signs such as respiration rate and heart rate is important to determine the occurrence of driver drowsiness. In this paper, robust vital signs monitoring through impulse radio ultra-wideband (IR-UWB) radar is discussed. We propose a new algorithm that can estimate the vital signs even if there is motion caused by the driving activities. We analyzed the whole fast time vital detection region and found the signals at those fast time locations that have useful information related to the vital signals. We segmented those signals into sub-signals and then constructed the desired vital signal using the correlation method. In this way, the vital signs of the driver can be monitored noninvasively, which can be used by researchers to detect the drowsiness of the driver which is related to the vital signs i.e., respiration and heart rate. In addition, texting on a mobile phone during driving may cause visual, manual or cognitive distraction of the driver. In order to reduce accidents caused by a distracted driver, we proposed an algorithm that can detect perfectly a driver's mobile phone usage even if there are various motions of the driver in the car or changes in background objects. These novel techniques, which monitor vital signs associated with drowsiness and detect phone usage before a driver makes a mistake, may be very helpful in developing techniques for preventing a car crash.

  8. Vital Sign Monitoring and Mobile Phone Usage Detection Using IR-UWB Radar for Intended Use in Car Crash Prevention

    Directory of Open Access Journals (Sweden)

    Seong Kyu Leem

    2017-05-01

    Full Text Available In order to avoid car crashes, active safety systems are becoming more and more important. Many crashes are caused due to driver drowsiness or mobile phone usage. Detecting the drowsiness of the driver is very important for the safety of a car. Monitoring of vital signs such as respiration rate and heart rate is important to determine the occurrence of driver drowsiness. In this paper, robust vital signs monitoring through impulse radio ultra-wideband (IR-UWB radar is discussed. We propose a new algorithm that can estimate the vital signs even if there is motion caused by the driving activities. We analyzed the whole fast time vital detection region and found the signals at those fast time locations that have useful information related to the vital signals. We segmented those signals into sub-signals and then constructed the desired vital signal using the correlation method. In this way, the vital signs of the driver can be monitored noninvasively, which can be used by researchers to detect the drowsiness of the driver which is related to the vital signs i.e., respiration and heart rate. In addition, texting on a mobile phone during driving may cause visual, manual or cognitive distraction of the driver. In order to reduce accidents caused by a distracted driver, we proposed an algorithm that can detect perfectly a driver's mobile phone usage even if there are various motions of the driver in the car or changes in background objects. These novel techniques, which monitor vital signs associated with drowsiness and detect phone usage before a driver makes a mistake, may be very helpful in developing techniques for preventing a car crash.

  9. Cell wall alterations in the leaves of fusariosis-resistant and susceptible pineapple cultivars.

    Science.gov (United States)

    de Farias Viégas Aquije, Glória Maria; Zorzal, Poliana Belisário; Buss, David Shaun; Ventura, José Aires; Fernandes, Patricia Machado Bueno; Fernandes, Antonio Alberto Ribeiro

    2010-10-01

    Fusariosis, caused by the fungus Fusarium subglutinans f. sp. ananas (Syn. F. guttiforme), is one of the main phytosanitary threats to pineapple (Ananas comosus var. comosus). Identification of plant cell responses to pathogens is important in understanding the plant-pathogen relationship and establishing strategies to improve and select resistant cultivars. Studies of the structural properties and phenolic content of cell walls in resistant (Vitoria) and susceptible (Perola) pineapple cultivars, related to resistance to the fungus, were performed. The non-chlorophyll base of physiologically mature leaves was inoculated with a conidia suspension. Analyses were performed post-inoculation by light, atomic force, scanning and transmission electron microscopy, and measurement of cell wall-bound phenolic compounds. Non-inoculated leaves were used as controls to define the constitutive tissue characteristics. Analyses indicated that morphological differences, such as cell wall thickness, cicatrization process and lignification, were related to resistance to the pathogen. Atomic force microscopy indicated a considerable difference in the mechanical properties of the resistant and susceptible cultivars, with more structural integrity, associated with higher levels of cell wall-bound phenolics, found in the resistant cultivar. p-Coumaric and ferulic acids were shown to be the major phenolics bound to the cell walls and were found in higher amounts in the resistant cultivar. Leaves of the resistant cultivar had reduced fungal penetration and a faster and more effective cicatrization response compared to the susceptible cultivar.

  10. CDC Vital Signs-Daily Pill Can Prevent HIV

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the November 24, 2015 CDC Vital Signs report. Preexposure prophylaxis, or PrEP, is a daily medicine that can be used to prevent getting HIV. PrEP is for people who don’t have HIV but who are at very high risk for getting it from sex or injection drug use. Unfortunately, many people who can benefit from PrEP aren’t taking it.

  11. CDC Vital Signs-E-cigarette Ads and Youth

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the January 2016 CDC Vital Signs report. Most electronic cigarettes, or e-cigarettes, contain nicotine, which is highly addictive and may harm brain development. More than 18 million middle and high school students were exposed to e-cigarette ads. Exposure to these ads may be contributing to an increase in e-cigarette use among youth. Learn what can be done to keep our youth safe and healthy.

  12. Gravity resistance, another graviresponse in plants - role of microtubule-membrane-cell wall continuum

    Science.gov (United States)

    Hoson, T.; Saito, Y.; Usui, S.; Soga, K.; Wakabayashi, K.

    Resistance to the gravitational force has been a serious problem for plants to survive on land, after they first went ashore more than 400 million years ago. Thus, gravity resistance is the principal graviresponse in plants comparable to gravitropism. Nevertheless, only limited information has been obtained for this second gravity response. We have examined the mechanism of gravity resistance using hypergravity conditions produced by centrifugation. The results led a hypothesis on the mechanism of plant resistance to the gravitational force that the plant constructs a tough body by increasing the cell wall rigidity, which are brought about by modification of the cell wall metabolism and cell wall environment, especially pH. The hypothesis was further supported by space experiments during the Space Shuttle STS-95 mission. On the other hand, we have shown that gravity signal may be perceived by mechanoreceptors (mechanosensitive ion channels) on the plasma membrane and amyloplast sedimentation in statocytes is not involved in gravity resistance. Moreover, hypergravity treatment increased the expression levels of genes encoding alpha-tubulin, a component of microtubules and 3-hydroxy-3-methylglutaryl-Coenzyme A reductase (HMGR), which catalyzes a reaction producing mevalonic acid, a key precursor of terpenoids such as membrane sterols. The expression of HMGR and alpha- and beta-tubulin genes increased within several hours after hypergravity treatment, depending on the magnitude of gravity. The determination of levels of gene products as well as the analysis with knockout mutants of these genes by T-DNA insertions in Arabidopsis supports the involvement of both membrane sterols and microtubules in gravity resistance. These results suggest that structural or physiological continuum of microtubule-cell membrane-cell wall is responsible for plant resistance to the gravitational force.

  13. Integrating human and environmental health in antibiotic risk assessment: A critical analysis of protection goals, species sensitivity and antimicrobial resistance.

    Science.gov (United States)

    Le Page, Gareth; Gunnarsson, Lina; Snape, Jason; Tyler, Charles R

    2017-12-01

    Antibiotics are vital in the treatment of bacterial infectious diseases but when released into the environment they may impact non-target organisms that perform vital ecosystem services and enhance antimicrobial resistance development with significant consequences for human health. We evaluate whether the current environmental risk assessment regulatory guidance is protective of antibiotic impacts on the environment, protective of antimicrobial resistance, and propose science-based protection goals for antibiotic manufacturing discharges. A review and meta-analysis was conducted of aquatic ecotoxicity data for antibiotics and for minimum selective concentration data derived from clinically relevant bacteria. Relative species sensitivity was investigated applying general linear models, and predicted no effect concentrations were generated for toxicity to aquatic organisms and compared with predicted no effect concentrations for resistance development. Prokaryotes were most sensitive to antibiotics but the range of sensitivities spanned up to several orders of magnitude. We show reliance on one species of (cyano)bacteria and the 'activated sludge respiration inhibition test' is not sufficient to set protection levels for the environment. Individually, neither traditional aquatic predicted no effect concentrations nor predicted no effect concentrations suggested to safeguard for antimicrobial resistance, protect against environmental or human health effects (via antimicrobial resistance development). Including data from clinically relevant bacteria and also more species of environmentally relevant bacteria in the regulatory framework would help in defining safe discharge concentrations for antibiotics for patient use and manufacturing that would protect environmental and human health. It would also support ending unnecessary testing on metazoan species. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  14. Aggressive chemotherapy and the selection of drug resistant pathogens.

    Directory of Open Access Journals (Sweden)

    Silvie Huijben

    2013-09-01

    Full Text Available Drug resistant pathogens are one of the key public health challenges of the 21st century. There is a widespread belief that resistance is best managed by using drugs to rapidly eliminate target pathogens from patients so as to minimize the probability that pathogens acquire resistance de novo. Yet strong drug pressure imposes intense selection in favor of resistance through alleviation of competition with wild-type populations. Aggressive chemotherapy thus generates opposing evolutionary forces which together determine the rate of drug resistance emergence. Identifying treatment regimens which best retard resistance evolution while maximizing health gains and minimizing disease transmission requires empirical analysis of resistance evolution in vivo in conjunction with measures of clinical outcomes and infectiousness. Using rodent malaria in laboratory mice, we found that less aggressive chemotherapeutic regimens substantially reduced the probability of onward transmission of resistance (by >150-fold, without compromising health outcomes. Our experiments suggest that there may be cases where resistance evolution can be managed more effectively with treatment regimens other than those which reduce pathogen burdens as fast as possible.

  15. Community Vitality: The Role of Community-Level Resilience Adaptation and Innovation in Sustainable Development

    Directory of Open Access Journals (Sweden)

    Lenore Newman

    2010-01-01

    Full Text Available Community level action towards sustainable development has emerged as a key scale of intervention in the effort to address our many serious environmental issues. This is hindered by the large-scale destruction of both urban neighbourhoods and rural villages in the second half of the twentieth century. Communities, whether they are small or large, hubs of experimentation or loci of traditional techniques and methods, can be said to have a level of community vitality that acts as a site of resilience, adaptation and innovation in the face of environmental challenges. This paper outlines how community vitality acts as a cornerstone of sustainable development and suggests some courses for future research. A meta-case analysis of thirty-five Canadian communities reveals the characteristics of community vitality emerging from sustainable development experiments and its relationship to resilience, applied specifically to community development.

  16. Proton Motive Force-Driven and ATP-Dependent Drug Extrusion Systems in Multidrug-Resistant Lactococcus lactis

    NARCIS (Netherlands)

    BOLHUIS, H; MOLENAAR, D; POELARENDS, G; VANVEEN, HW; POOLMAN, B; DRIESSEN, AJM; KONINGS, WN

    1994-01-01

    Three mutants of Lactococcus lactis subsp. lactis MG1363, termed Eth(R), Dau(R), and Rho(R), were selected for resistance to high concentrations of ethidium bromide, daunomycin, and rhodamine 6G, respectively. These mutants were found to be cross resistant to a number of structurally and

  17. A simple intervention improves the recording of vital signs in children presenting to the emergency department.

    Science.gov (United States)

    Bird, C; Shea, A; Michie, C A; George, G

    2009-10-01

    Vital signs are often not documented in paediatric patients at triage. This study was conducted to find out whether the use of a small, laminated aide memoire and a short teaching session might improve this situation. A preliminary audit of the measurement of vital signs in 106 children aged less than 6 years was carried out in a district general hospital emergency department (ED). A small card illustrating normal values for these was then distributed-this could be attached to staff identity cards. At the same time doctors and nursing staff were given a teaching session on the importance of these measures. The audit was then repeated in a further 106 children. There was significant improvement in recording of all vital signs with the exception of blood pressure and temperature. A low-cost card together with a short period of training offers a useful strategy to improve the rate of documentation of vital signs in children presenting to the ED.

  18. Os postulados de Nightingale e Semmelweis: poder/vital e prevenção/contágio como estratégias para a evitabilidade das infecções Los postulados de Nightingale y Semmelweis: energía vital/vida y prevención/contágio como estrategias para evitar las infecciones Nightingale's and Semmelweis' postulates: vital power and contagion prevention as strategies to avoid infections

    Directory of Open Access Journals (Sweden)

    Telma Elisa Carraro

    2004-08-01

    Full Text Available Trata-se de pesquisa qualitativa, que utilizou a observação como técnica para coleta de dados, tendo como guia um instrumento elaborado a partir de postulados de Florence Nightingale e Ignaz Phillip Semmelweis: poder vital/vida e prevenção/contágio. Registra breve histórico sobre o controle de infecções, destacando o enfoque prevenção/contágio. Discorre sobre o postulado poder vital/vida, apresentando e discutindo os componentes da assistência de Enfermagem dele decorrentes para o desenvolvimento da assistência. Recomenda que se considere articuladamente as vertentes - Poder Vital/Vida e Prevenção/Contágio - como estratégias para a evitabilidade das infecções.Esta investigación cualitativa utilizó la observación como técnica de recolección de datos, guiándose por un instrumento basado en los postulados de Florence Nightingale e Ignaz Phillip Semmelweis: energía vital/vida y prevención/contagio. Presenta un breve histórico acerca del control de infección, destacando el enfoque prevención/contagio. Habla sobre el postulado energía vital/vida, presentando y discutiendo los componentes de la asistencia de enfermería que se desprenden de él para el desarrollo de la asistencia. Concluye recomendando que se considere articuladamente las vertientes energía vital/vida y prevención/contagio como estrategia para evitar las infecciones.This qualitative research used observation as a data collection technique, guided by an instrument elaborated on the basis of Nightingale and Semmelweis' postulates: vital power/life and prevention/contagion. A brief history of infection control is offered from the focus of prevention/contagion. The postulate vital power/life is discussed, presenting the nursing care components deriving from it with a view to care development. This study recommends that both postulates - vital power/life and prevention/contagion - be considered in an articulated way as strategies to avoid infections.

  19. Adhesion force of staphylococcus aureus on various biomaterial surfaces.

    Science.gov (United States)

    Alam, Fahad; Balani, Kantesh

    2017-01-01

    Staphylococcus comprises of more than half of all pathogens in orthopedic implant infections and they can cause major bone infection which can result in destruction of joint and bone. In the current study, adhesion force of bacteria on the surface of various biomaterial surfaces is measured using atomic force microscope (AFM). Staphylococcus aureus was immobilized on an AFM tipless cantilever as a force probe to measure the adhesion force between bacteria and biomaterials (viz. ultra-high molecular weight poly ethylene (UHMWPE), stainless steel (SS), Ti-6Al-4V alloy, hydroxyapatite (HA)). At the contact time of 10s, UHMWPE shows weak adhesion force (~4nN) whereas SS showed strong adhesion force (~15nN) due to their surface energy and surface roughness. Bacterial retention and viability experiment (3M™ petrifilm test, agar plate) dictates that hydroxyapatite shows the lowest vaibility of bacteria, whereas lowest bacterial retention is observed on UHMWPE surface. Similar results were obtained from live/dead staining test, where HA shows 65% viability, whereas on UHMWPE, SS and Ti-6Al-4V, the bacterial viability is 78%, 94% and 97%, respectively. Lower adhesion forces, constrained pull-off distance (of bacterial) and high antibacterial resistance of bioactive-HA makes it a potential biomaterial for bone-replacement arthroplasty. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. CDC Vital Signs–Dental Sealants Prevent Cavities

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the October 2016 CDC Vital Signs report. Dental sealants, applied soon after a child's permanent molars come in, can protect against cavities for up to nine years. Applying sealants in schools for low-income children could save millions in dental treatment costs.

  1. CDC Vital Signs-Zika and Pregnancy: What You Should Know

    Centers for Disease Control (CDC) Podcasts

    This podcast is based on the April 2016 CDC Vital Signs report. A pregnant woman who is infected with Zika virus can pass it to her fetus which is linked to microcephaly, a serious birth defect. This podcast discusses how to protect yourself from Zika virus.

  2. Cancer cachexia decreases specific force and accelerates fatigue in limb muscle

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, B. M. [1225 Center Drive, HPNP Building Room 1142, Department of Physical Therapy, University of Florida, Gainesville, FL 32610 (United States); Frye, G. S.; Ahn, B.; Ferreira, L. F. [1864 Stadium Road, Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL 32610 (United States); Judge, A.R., E-mail: arjudge@phhp.ufl.edu [1225 Center Drive, HPNP Building Room 1142, Department of Physical Therapy, University of Florida, Gainesville, FL 32610 (United States)

    2013-06-07

    Highlights: •C-26 cancer cachexia causes a significant decrease in limb muscle absolute force. •C-26 cancer cachexia causes a significant decrease in limb muscle specific force. •C-26 cancer cachexia decreases fatigue resistance in the soleus muscle. •C-26 cancer cachexia prolongs time to peak twitch tension in limb muscle. •C-26 cancer cachexia prolongs one half twitch relaxation time in limb muscle. -- Abstract: Cancer cachexia is a complex metabolic syndrome that is characterized by the loss of skeletal muscle mass and weakness, which compromises physical function, reduces quality of life, and ultimately can lead to mortality. Experimental models of cancer cachexia have recapitulated this skeletal muscle atrophy and consequent decline in muscle force generating capacity. However, more recently, we provided evidence that during severe cancer cachexia muscle weakness in the diaphragm muscle cannot be entirely accounted for by the muscle atrophy. This indicates that muscle weakness is not just a consequence of muscle atrophy but that there is also significant contractile dysfunction. The current study aimed to determine whether contractile dysfunction is also present in limb muscles during severe Colon-26 (C26) carcinoma cachexia by studying the glycolytic extensor digitorum longus (EDL) muscle and the oxidative soleus muscle, which has an activity pattern that more closely resembles the diaphragm. Severe C-26 cancer cachexia caused significant muscle fiber atrophy and a reduction in maximum absolute force in both the EDL and soleus muscles. However, normalization to muscle cross sectional area further demonstrated a 13% decrease in maximum isometric specific force in the EDL and an even greater decrease (17%) in maximum isometric specific force in the soleus. Time to peak tension and half relaxation time were also significantly slowed in both the EDL and the solei from C-26 mice compared to controls. Since, in addition to postural control, the oxidative

  3. Cancer cachexia decreases specific force and accelerates fatigue in limb muscle

    International Nuclear Information System (INIS)

    Roberts, B.M.; Frye, G.S.; Ahn, B.; Ferreira, L.F.; Judge, A.R.

    2013-01-01

    Highlights: •C-26 cancer cachexia causes a significant decrease in limb muscle absolute force. •C-26 cancer cachexia causes a significant decrease in limb muscle specific force. •C-26 cancer cachexia decreases fatigue resistance in the soleus muscle. •C-26 cancer cachexia prolongs time to peak twitch tension in limb muscle. •C-26 cancer cachexia prolongs one half twitch relaxation time in limb muscle. -- Abstract: Cancer cachexia is a complex metabolic syndrome that is characterized by the loss of skeletal muscle mass and weakness, which compromises physical function, reduces quality of life, and ultimately can lead to mortality. Experimental models of cancer cachexia have recapitulated this skeletal muscle atrophy and consequent decline in muscle force generating capacity. However, more recently, we provided evidence that during severe cancer cachexia muscle weakness in the diaphragm muscle cannot be entirely accounted for by the muscle atrophy. This indicates that muscle weakness is not just a consequence of muscle atrophy but that there is also significant contractile dysfunction. The current study aimed to determine whether contractile dysfunction is also present in limb muscles during severe Colon-26 (C26) carcinoma cachexia by studying the glycolytic extensor digitorum longus (EDL) muscle and the oxidative soleus muscle, which has an activity pattern that more closely resembles the diaphragm. Severe C-26 cancer cachexia caused significant muscle fiber atrophy and a reduction in maximum absolute force in both the EDL and soleus muscles. However, normalization to muscle cross sectional area further demonstrated a 13% decrease in maximum isometric specific force in the EDL and an even greater decrease (17%) in maximum isometric specific force in the soleus. Time to peak tension and half relaxation time were also significantly slowed in both the EDL and the solei from C-26 mice compared to controls. Since, in addition to postural control, the oxidative

  4. The antibiotic resistance "mobilome": searching for the link between environment and clinic.

    Science.gov (United States)

    Perry, Julie A; Wright, Gerard D

    2013-01-01

    Antibiotic resistance is an ancient problem, owing to the co-evolution of antibiotic-producing and target organisms in the soil and other environments over millennia. The environmental "resistome" is the collection of all genes that directly or indirectly contribute to antibiotic resistance. Many of these resistance determinants originate in antibiotic-producing organisms (where they serve to mediate self-immunity), while others become resistance determinants only when mobilized and over-expressed in non-native hosts (like plasmid-encoded β-lactamases). The modern environmental resistome is under selective pressure from human activities such as agriculture, which may influence the composition of the local resistome and lead to gene transfer events. Beyond the environment, we are challenged in the clinic by the rise in both frequency and diversity of antibiotic resistant pathogens. We assume that clinical resistance originated in the environment, but few examples of direct gene exchange between the environmental resistome and the clinical resistome have been documented. Strong evidence exists to suggest that clinical aminoglycoside and vancomycin resistance enzymes, the extended-spectrum β-lactamase CTX-M and the quinolone resistance gene qnr have direct links to the environmental resistome. In this review, we highlight recent advances in our understanding of horizontal gene transfer of antibiotic resistance genes from the environment to the clinic. Improvements in sequencing technologies coupled with functional metagenomic studies have revealed previously underappreciated diversity in the environmental resistome, and also established novel genetic links to the clinic. Understanding mechanisms of gene exchange becomes vital in controlling the future dissemination of antibiotic resistance.

  5. Topology determines force distributions in one-dimensional random spring networks

    Science.gov (United States)

    Heidemann, Knut M.; Sageman-Furnas, Andrew O.; Sharma, Abhinav; Rehfeldt, Florian; Schmidt, Christoph F.; Wardetzky, Max

    2018-02-01

    Networks of elastic fibers are ubiquitous in biological systems and often provide mechanical stability to cells and tissues. Fiber-reinforced materials are also common in technology. An important characteristic of such materials is their resistance to failure under load. Rupture occurs when fibers break under excessive force and when that failure propagates. Therefore, it is crucial to understand force distributions. Force distributions within such networks are typically highly inhomogeneous and are not well understood. Here we construct a simple one-dimensional model system with periodic boundary conditions by randomly placing linear springs on a circle. We consider ensembles of such networks that consist of N nodes and have an average degree of connectivity z but vary in topology. Using a graph-theoretical approach that accounts for the full topology of each network in the ensemble, we show that, surprisingly, the force distributions can be fully characterized in terms of the parameters (N ,z ) . Despite the universal properties of such (N ,z ) ensembles, our analysis further reveals that a classical mean-field approach fails to capture force distributions correctly. We demonstrate that network topology is a crucial determinant of force distributions in elastic spring networks.

  6. Faculty Vitality in "Different Worlds": The View from Three Academic Areas. ASHE 1988 Annual Meeting Paper.

    Science.gov (United States)

    Baldwin, Roger G.

    The professional lives of "vital" professors in the areas of arts and humanities, mathematics and natural sciences, and the social sciences are examined, and common and subject-area specific factors (such as attributes, activities, and sources of support) closely associated with faculty vitality are identified. Subjects were chosen from…

  7. CDC Vital Signs–Preventing Stroke Deaths

    Centers for Disease Control (CDC) Podcasts

    2017-09-06

    This podcast is based on the September 2017 CDC Vital Signs report. Each year, more than 140,000 people die and many survivors face disability. Eighty percent of strokes are preventable. Learn the signs of stroke and how to prevent them.  Created: 9/6/2017 by Centers for Disease Control and Prevention (CDC).   Date Released: 9/6/2017.

  8. Vitality detection in personal authentication systems using fingerprints

    OpenAIRE

    Coli, Pietro

    2008-01-01

    Fingerprints are considered as the sign of each human being, and this has contributed the development of biometric applications based on such features. Since 2002, an important vulnerability has been shown: it is possible to deceive fingerprint scanners through artificial replicas of fingertips. In order to address this shortcoming it is need to recognize a spoofing attempt with artificial fingers looking for some “life signs” each time an user submit a fingerprint (vitality detection problem...

  9. Effectiveness of a worksite lifestyle intervention on vitality, work engagement, productivity, and sick leave: results of a randomized controlled trial.

    Science.gov (United States)

    Strijk, Jorien E; Proper, Karin I; van Mechelen, Willem; van der Beek, Allard J

    2013-01-01

    A worksite lifestyle intervention aiming to improve lifestyle behaviors could be an effective tool to keep older workers vital, and thereby prolong their labor participation. Therefore, this study evaluates the effectiveness of such an intervention on vitality, work engagement, productivity and sick leave. In a randomized controlled trial design, 367 workers (control group: N=363) received a 6-month intervention, which included two weekly guided group sessions: one yoga and one workout, as well as one weekly session of aerobic exercising, without face-to-face instruction, and three individual coach visits aimed at changing workers' lifestyle behavior by goal setting, feedback, and problem-solving strategies. Furthermore, free fruit was provided at the guided sessions. Data on work-related vitality (UWES vitality scale), general vitality (RAND-36 vitality scale), work engagement (UWES), productivity (single item scoring 0-10), and sick leave (yes/no past 3 months) were collected using questionnaires at baseline (N=730), and at 6- (N=575) and 12-months (N=500) follow-up. Effects were analyzed according to the intention-to-treat principle with complete cases (N=500) and imputed data (N=730). There were no significant differences in vitality, work engagement, productivity, and sick leave between the intervention and control group workers after either 6- and 12-months follow-up. Yoga and workout subgroup analyses showed a 12-month favorable effect on work-related vitality [β=0.14, 95% confidence interval (95% CI) 0.04-0.28] and general vitality (β=2.9, 95% CI 0.02-5.9) among high yoga compliers. For high workout compliers, this positive trend was also seen, but it was not statistically significant. Implementation of worksite yoga facilities could be a useful strategy to promote vitality-related work outcomes, but only if high compliance can be maximized. Therefore, impeding factors for participation should be investigated in more detail in future research.

  10. Driving reconnection in sheared magnetic configurations with forced fluctuations

    Science.gov (United States)

    Pongkitiwanichakul, Peera; Makwana, Kirit D.; Ruffolo, David

    2018-02-01

    We investigate reconnection of magnetic field lines in sheared magnetic field configurations due to fluctuations driven by random forcing by means of numerical simulations. The simulations are performed with an incompressible, pseudo-spectral magnetohydrodynamics code in 2D where we take thick, resistively decaying, current-sheet like sheared magnetic configurations which do not reconnect spontaneously. We describe and test the forcing that is introduced in the momentum equation to drive fluctuations. It is found that the forcing does not change the rate of decay; however, it adds and removes energy faster in the presence of the magnetic shear structure compared to when it has decayed away. We observe that such a forcing can induce magnetic reconnection due to field line wandering leading to the formation of magnetic islands and O-points. These reconnecting field lines spread out as the current sheet decays with time. A semi-empirical formula is derived which reasonably explains the formation and spread of O-points. We find that reconnection spreads faster with stronger forcing and longer correlation time of forcing, while the wavenumber of forcing does not have a significant effect. When the field line wandering becomes large enough, the neighboring current sheets with opposite polarity start interacting, and then the magnetic field is rapidly annihilated. This work is useful to understand how forced fluctuations can drive reconnection in large scale current structures in space and astrophysical plasmas that are not susceptible to reconnection.

  11. Pulpal inflammation after vital tooth bleaching with 38% hydrogen peroxide

    Directory of Open Access Journals (Sweden)

    Ardiny Andriani

    2012-06-01

    Full Text Available Background: In-office vital tooth bleaching is a treatment to remove tooth stains. Tooth sensitivity is one of side effect commonly complained by patients receiving this treatment. Purpose: The aim of this study was to examine histological inflammatory cells infiltration of dental pulp after application of 38% H2O2 as a vital tooth bleaching agent. Methods: Under informed consent, a total of 15 premolars from 8 healthy subjects scheduled for orthodontic extraction were used in this study. Thirty eight percent H2O2 was applied on the buccal surface of the treated group. The treated teeth were extracted after 1 hour, 5, 8, and 15 days. All specimens were embedded in paraffin wax, sectioned serially and stained with Hematoxyllin Eosin. Histological specimens were then observed under a light microscope. Results: All treated groups showed a slight disorganization of odontoblasts layer and slight inflammation in the pulp tissue adjacent to the 38% H2O2 application site. The number of polymorphonuclear leukocytes (PMN had increased significantly 1 hour after application of 38% H2O2 (p<0.05, while macrophages had significantly increased 5 days after the application (p<0.05. The most intense PMN and macrophages infiltration was found 5 days after the application and gradually decreased 8 days after application of38% H2O2. Conclusion: Application of 38% H2O2 as a vital tooth bleaching agent induces acute inflammation in human dental pulp; however, the inflammation will decrease 8 days after the application.Latar belakang: Perawatan pemutihan gigi vital metode in-office merupakan tindakan untuk menghilangkan pewarnaan pada gigi. Salah satu efek samping yang sering dikeluhkan oleh pasien yang menjalani perawatan ini adalah sensitivitas gigi. Tujuan: Penelitian ini bertujuan untuk mengamati infiltrasi sel inflamasi pada pulpa gigi setelah aplikasi H2O2 38% sebagai bahan pemutih gigi. Metode: Sampel penelitian ini berupa 15 gigi premolar yang berasal dari 8

  12. Adult mouse motor units develop almost all of their force in the subprimary range: a new all-or-none strategy for force recruitment?

    Science.gov (United States)

    Manuel, Marin; Heckman, C J

    2011-10-19

    Classical studies of the mammalian neuromuscular system have shown an impressive adaptation match between the intrinsic properties of motoneurons and the contractile properties of their motor units. In these studies, the rate at which motoneurons start to fire repetitively corresponds to the rate at which individual twitches start to sum, and the firing rate increases linearly with the amount of excitation ("primary range") up to the point where the motor unit develops its maximal force. This allows for the gradation of the force produced by a motor unit by rate modulation. In adult mouse motoneurons, however, we recently described a regime of firing ("subprimary range") that appears at lower excitation than what is required for the primary range, a finding that might challenge the classical conception. To investigate the force production of mouse motor units, we simultaneously recorded, for the first time, the motoneuron discharge elicited by intracellular ramps of current and the force developed by its motor unit. We showed that the motor unit developed nearly its maximal force during the subprimary range. This was found to be the case regardless of the input resistance of the motoneuron, the contraction speed, or the tetanic force of the motor unit. Our work suggests that force modulation in small mammals mainly relies on the number of motor units that are recruited rather than on rate modulation of individual motor units.

  13. Simultaneous vitality and DNA-fragmentation measurement in spermatozoa of smokers and non-smokers.

    Science.gov (United States)

    De Bantel, A; Fleury-Feith, J; Poirot, C; Berthaut, I; Garcin, C; Landais, P; Ravel, C

    2015-03-01

    Because cigarette smoke is a powerful ROS producer, we hypothesized that the spermatozoa of smokers would be more at risk of having increased DNA fragmentation than spermatozoa of non-smoking men. A cross-sectional study was performed on consenting smokers and non-smokers, consulting in an infertility clinic for routine sperm analysis. The application of a novel TUNEL assay coupled to a vitality marker, LIVE/DEAD®, allowed both DNA fragmentation and viability measurement within spermatozoa of participants to be analyzed by flow cytometry. The coupled vitality-DNA fragmentation analysis revealed that non-smokers and smokers, respectively presented medians of 3.6% [0.6-36.8] and 3.3% [0.9-9.6] DNA fragmented spermatozoa among the living spermatozoa population (P > 0.05). No deleterious effect of smoking on spermatozoa was found in our study. More studies concerning potential mutagenic capacities of cigarette smoke on spermatozoa are necessary. In addition, the coupled vitality-DNA fragmentation analysis may orient Assisted Reproductive Technology teams when confronted with patients having a high percentage of DNA-fragmented living spermatozoa. © 2014 International Clinical Cytometry Society.

  14. Pediatric Vital Sign Distribution Derived From a Multi-Centered Emergency Department Database

    Directory of Open Access Journals (Sweden)

    Robert J. Sepanski

    2018-03-01

    Full Text Available BackgroundWe hypothesized that current vital sign thresholds used in pediatric emergency department (ED screening tools do not reflect observed vital signs in this population. We analyzed a large multi-centered database to develop heart rate (HR and respiratory rate centile rankings and z-scores that could be incorporated into electronic health record ED screening tools and we compared our derived centiles to previously published centiles and Pediatric Advanced Life Support (PALS vital sign thresholds.MethodsInitial HR and respiratory rate data entered into the Cerner™ electronic health record at 169 participating hospitals’ ED over 5 years (2009 through 2013 as part of routine care were analyzed. Analysis was restricted to non-admitted children (0 to <18 years. Centile curves and z-scores were developed using generalized additive models for location, scale, and shape. A split-sample validation using two-thirds of the sample was compared with the remaining one-third. Centile values were compared with results from previous studies and guidelines.ResultsHR and RR centiles and z-scores were determined from ~1.2 million records. Empirical 95th centiles for HR and respiratory rate were higher than previously published results and both deviated from PALS guideline recommendations.ConclusionHeart and respiratory rate centiles derived from a large real-world non-hospitalized ED pediatric population can inform the modification of electronic and paper-based screening tools to stratify children by the degree of deviation from normal for age rather than dichotomizing children into groups having “normal” versus “abnormal” vital signs. Furthermore, these centiles also may be useful in paper-based screening tools and bedside alarm limits for children in areas other than the ED and may establish improved alarm limits for bedside monitors.

  15. Turbulent resistivity driven by the magnetorotational instability

    Science.gov (United States)

    Fromang, S.; Stone, J. M.

    2009-11-01

    Aims: We measure the turbulent resistivity in the nonlinear regime of the MRI, and evaluate the turbulent magnetic Prandtl number. Methods: We perform a set of numerical simulations with the Eulerian finite volume codes Athena and Ramses in the framework of the shearing box model. We consider models including explicit dissipation coefficients and magnetic field topologies such that the net magnetic flux threading the box in both the vertical and azimuthal directions vanishes. Results: We first demonstrate good agreement between the two codes by comparing the properties of the turbulent states in simulations having identical microscopic diffusion coefficients (viscosity and resistivity). We find the properties of the turbulence do not change when the box size is increased in the radial direction, provided it is elongated in the azimuthal direction. To measure the turbulent resistivity in the disk, we impose a fixed electromotive force on the flow and measure the amplitude of the saturated magnetic field that results. We obtain a turbulent resistivity that is in rough agreement with mean field theories like the Second Order Smoothing Approximation. The numerical value translates into a turbulent magnetic Prandtl number Pmt of order unity. Pmt appears to be an increasing function of the forcing we impose. It also becomes smaller as the box size is increased in the radial direction, in good agreement with previous results obtained in very large boxes. Conclusions: Our results are in general agreement with other recently published papers studying the same problem but using different methodology. Thus, our conclusion that Pmt is of order unity appears robust.

  16. Shape memory alloy resistance behaviour at high altitude for feedback control

    Science.gov (United States)

    Ng, W. T.; Sedan, M. F.; Abdullah, E. J.; Azrad, S.; Harithuddin, A. S. M.

    2017-12-01

    Many recent aerospace technologies are using smart actuators to reduce the system's complexity and increase its reliability. One such actuator is shape memory alloy (SMA) actuator, which is lightweight, produces high force and large deflection. However, some disadvantages in using SMA actuators have been identified and they include nonlinear response of the strain to input current, hysteresis characteristic that results in inaccurate control and less than optimum system performance, high operating temperatures, slow response and also high requirement of electrical power to obtain the desired actuation forces. It is still unknown if the SMA actuators can perform effectively at high altitude with low surrounding temperature. The work presented here covers the preliminary process of verifying the feasibility of using resistance as feedback control at high altitude for aerospace applications. Temperature and resistance of SMA actuator at high altitude is investigated by conducting an experiment onboard a high altitude balloon. The results from the high altitude experiment indicate that the resistance or voltage drop of the SMA wire is not significantly affected by the low surrounding temperature at high altitude as compared to the temperature of SMA. Resistance feedback control for SMA actuators may be suitable for aerospace applications.

  17. Immunomodulation by LongoVital in patients with recurrent aphthous ulceration

    DEFF Research Database (Denmark)

    Pedersen, A; Klausen, B; Hougen, H P

    1990-01-01

    LongoVital (LV) (DK. Reg. No. 5178/75) is a herbal based tablet enriched with recommended doses of vitamins. Peripheral lymphocyte subsets: T-helper/CD4 (OKT4+) and T-suppressor/cytotoxic/CD8 (OKT8+) were studied quantitatively in 31 otherwise healthy patients with minor recurrent aphthous...

  18. Testing and Modeling of Machine Properties in Resistance Welding

    DEFF Research Database (Denmark)

    Wu, Pei

    The objective of this work has been to test and model the machine properties including the mechanical properties and the electrical properties in resistance welding. The results are used to simulate the welding process more accurately. The state of the art in testing and modeling machine properties...... as real projection welding tests, is easy to realize in industry, since tests may be performed in situ. In part II, an approach of characterizing the electrical properties of AC resistance welding machines is presented, involving testing and mathematical modelling of the weld current, the firing angle...... in resistance welding has been described based on a comprehensive literature study. The present thesis has been subdivided into two parts: Part I: Mechanical properties of resistance welding machines. Part II: Electrical properties of resistance welding machines. In part I, the electrode force in the squeeze...

  19. Setting priorities for a research agenda to combat drug-resistant tuberculosis in children.

    Science.gov (United States)

    Velayutham, B; Nair, D; Ramalingam, S; Perez-Velez, C M; Becerra, M C; Swaminathan, S

    2015-12-21

    Numerous knowledge gaps hamper the prevention and treatment of childhood drug-resistant tuberculosis (TB). Identifying research priorities is vital to inform and develop strategies to address this neglected problem. To systematically identify and rank research priorities in childhood drug-resistant TB. Adapting the Child Health and Nutrition Research Initiative (CHNRI) methodology, we compiled 53 research questions in four research areas, then classified the questions into three research types. We invited experts in childhood drug-resistant TB to score these questions through an online survey. A total of 81 respondents participated in the survey. The top-ranked research question was to identify the best combination of existing diagnostic tools for early diagnosis. Highly ranked treatment-related questions centred on the reasons for and interventions to improve treatment outcomes, adverse effects of drugs and optimal treatment duration. The prevalence of drug-resistant TB was the highest-ranked question in the epidemiology area. The development type questions that ranked highest focused on interventions for optimal diagnosis, treatment and modalities for treatment delivery. This is the first effort to identify and rank research priorities for childhood drug-resistant TB. The result is a resource to guide research to improve prevention and treatment of drug-resistant TB in children.

  20. INFLUENCING OF FRICTION IN HINGES FORCE SIZE OF BARS

    Directory of Open Access Journals (Sweden)

    BOHOMAZ V. N.

    2016-04-01

    Full Text Available Formulation of the problem. The size of critical force of bar on the traditional method of calculation is determined in supposition of ideal hinge in the place of fixing of bar. There are both a hinge resistance at the turn of bar ends and their moving in the real hinges. Thus, there is the necessity of influencing character determination of these hinge imperfections on the size of critical force. In the existent scientific labours is devoted the alike problems, influencing of friction in the hinges of bar fastening on the size of critical force was not taken into account. At determination of bars stability with no ideality of hinges friction in them it is possible to take into account by the eccentric appendix of loading or appendix of moment. However at such approach it is difficult enough to define the size of attached force or moment. Purpose. To set influencing of friction in the hinge of bar fastening on of his critical force size in sense of Euler, and also build dependences for determination of bar critical force taking into account mechanical descriptions of hinges materials. Conclusion. For the task of determination the size of bar critical force with the joint fastening on ends are got the dependences which take into account mechanical descriptions of material hinge. The received dependences allow to define more exact meaning of critical force for bars. The examples of calculation of whole bar and bar with undercuting in the middle are resulted that values of critical force, certain on a traditional method are overpriced.