The HITRAP project at GSI

International Nuclear Information System (INIS)

Poth, H.; Hasse, R.W.

1990-10-01

We present a proposal for the development of a facility to capture highly-charged ions, produced in the GSI heavy ion complex, and to store them in electromagnetic traps at thermal or subthermal energy. Such a facility would allow to exploit the physics opened up by the heavy ion rings SIS and ESR and by the fragment separator FRS with unprecedented possibilities as will be shown in the outlined physics program. (orig.)

Some problems of residual activity measurements

International Nuclear Information System (INIS)

Katrik, P.; Mustafin, E.; Strasik, I.; Pavlovic, M.

2013-01-01

As a preparatory work for constructing the Facility for Antiproton and Ion Research (FAIR) at GSI Darmstadt, samples of copper were irradiated by 500 MeV/u 238 U ion beam and investigated by gamma-ray spectroscopy. The nuclides that contribute dominantly to the residual activity have been identified and their contributions have been quantified by two different methods: from the whole-target gamma spectra and by integration of depth-profiles of residual activity of individual nuclides. Results obtained by these two methods are compared and discussed in this paper. (authors)

GSI research and development programme 1983-85

International Nuclear Information System (INIS)

1982-01-01

In this report the research program of the GSI Darmstadt is described. This program concerns heavy ion reactions, atomic collisions with heavy ions, and applications of heavy ion beams in other fields of science. Furthermore the future development of accelerators and detection methods is described. (HSI) [de

Construction and characterization of a laser-driven proton beamline at GSI

OpenAIRE

Busold, Simon

2014-01-01

The thesis includes the first experiments with the new 100 TW laser beamline of the PHELIX laser facility at GSI Darmstadt to drive a TNSA (Target Normal Sheath Acceleration) proton source at GSI's Z6 experimental area. At consecutive stages a pulsed solenoid has been applied for beam transport and energy selection via chromatic focusing, as well as a radiofrequency cavity for energy compression of the bunch. This novel laser-driven proton beamline, representing a central experiment of the...

Impact of hybrid GSI analysis using ETR ensembles

Indian Academy of Sciences (India)

Impact of hybrid GSI analysis using ETR ensembles. V S Prasad∗ and C J .... In this study, impact of hybrid ..... of water between vapour, clouds and ice (Damrath et al. 2000). ... flooding – June 2013; Weather and Climate Extremes 4. 22–34.

Extra lethal damage due to residual incompletely repaired sublethal damage in hyperfractionated and continuous radiation treatment

Energy Technology Data Exchange (ETDEWEB)

Chen, J.; van de Geijn, J.; Goffman, T. (ROB, DCT, NCI, NIH, Bethesda, Maryland 20892 (US))

1991-05-01

In the conventional linear--quadratic model of single-dose response, the {alpha} and {beta} terms reflect lethal damage created {ital during} the delivery of a dose, from two different presumed molecular processes, one linear with dose, the other quadratic. With the conventional one-fraction-per-day (or less) regimens, the sublethal damage (SLD), presumably repairing exponentially over time, is essentially completely fixed by the time of the next dose of radiation. If this assumption is true, the effects of subsequent fractions of radiation should be independent, that is, there should be little, if any, reversible damage left from previous fractions, at the time of the next dose. For multiple daily fractions, or for the limiting case, continuous radiation, this simplification may overlook damaged cells that have had insufficient time for repair. A generalized method is presented for accounting for extra lethal damage (ELD) arising from such residual SLD for hyperfractionation and continuous irradiation schemes. It may help to predict differences in toxicity and tumor control, if any, obtained with unconventional'' treatment regimens. A key element in the present model is the finite size and the dynamic character of the pool of sublethal damage. Besides creating the usual linear and quadratic components of lethal damage, each new fraction converts a certain fraction of the existing SLD into ELD, and creates some new SLD.

Extra lethal damage due to residual incompletely repaired sublethal damage in hyperfractionated and continuous radiation treatment

International Nuclear Information System (INIS)

Chen, J.; van de Geijn, J.; Goffman, T.

1991-01-01

In the conventional linear--quadratic model of single-dose response, the α and β terms reflect lethal damage created during the delivery of a dose, from two different presumed molecular processes, one linear with dose, the other quadratic. With the conventional one-fraction-per-day (or less) regimens, the sublethal damage (SLD), presumably repairing exponentially over time, is essentially completely fixed by the time of the next dose of radiation. If this assumption is true, the effects of subsequent fractions of radiation should be independent, that is, there should be little, if any, reversible damage left from previous fractions, at the time of the next dose. For multiple daily fractions, or for the limiting case, continuous radiation, this simplification may overlook damaged cells that have had insufficient time for repair. A generalized method is presented for accounting for extra lethal damage (ELD) arising from such residual SLD for hyperfractionation and continuous irradiation schemes. It may help to predict differences in toxicity and tumor control, if any, obtained with ''unconventional'' treatment regimens. A key element in the present model is the finite size and the dynamic character of the pool of sublethal damage. Besides creating the usual linear and quadratic components of lethal damage, each new fraction converts a certain fraction of the existing SLD into ELD, and creates some new SLD

Residual tree damage during selection cuts using two skidding systems in the Missouri Ozarks

Science.gov (United States)

Robert L. Ficklin; John P. Dwyer; Bruce E. Cutter; Tom Draper

1997-01-01

Today, there is an interest in using alternative silvicultural systems like selection and two-aged management, because the public finds these systems more acceptable than clearcutting. However, repeated entries into forest stands to remove timber increase the risk of residual stand damage. Harvest techniques are desirable that (1) reduce the risk of stand damage and (2...

Rock mass classification system : transition from RMR to GSI.

Science.gov (United States)

2013-11-01

The AASHTO LRFD Bridge Design Specifications is expected to replace the rock mass rating : (RMR) system with the Geological Strength Index (GSI) system for classifying and estimating : engineering properties of rock masses. This transition is motivat...

Residual Strength Analysisof Asymmetrically Damaged Ship Hull GirderUsing Beam Finite Element Method

Directory of Open Access Journals (Sweden)

Muhammad Zubair Muis Alie

2016-04-01

Full Text Available The objective of the present study is to analyze the residual strength of asymmetrically damaged ship hull girder under longitudinal bending. Beam Finite Element Method isused for the assessment of the residual strength of two single hull bulk carriers (Ship B1 and Ship B4 and a three-cargo-hold model of a single-side Panamax Bulk Carrierin hogging and sagging conditions. The Smith’s  method  is  adopted  and  implemented  into  Beam  Finite  Element Method. An efficient solution procedure is applied; i.e. by assuming the cross section remains plane, the vertical bending moment is applied to the  cross section  and  three-cargo-hold  model. As a fundamental  case,  the  damage is simply  created  by removing the elements from the cross section, neglecting any welding residual stress and initial imperfection. Also no crack  extension  is considered.  The  result  obtained  by  Beam  Finite  Element  Method  so-called Beam-HULLST is compared to the progressive collapse analysis obtained by HULLST for the validation of the present work. Then, for the three-hold-model, the Beam-HULLST is used to investigate the effect of the rotation of the netral axisboth intact and damage condition taking the one and five frame spaces into account. 

Benchmark calculations on residue production within the EURISOL DS project; Part I: thin targets

CERN Document Server

David, J.C; Boudard, A; Doré, D; Leray, S; Rapp, B; Ridikas, D; Thiollière, N

Report on benchmark calculations on residue production in thin targets. Calculations were performed using MCNPX 2.5.0 coupled to a selection of reaction models. The results were compared to nuclide production cross-sections measured in GSI in inverse kinematics

The numerical high cycle fatigue damage model of fillet weld joint under weld-induced residual stresses

Science.gov (United States)

Nguyen Van Do, Vuong

2018-04-01

In this study, a development of nonlinear continuum damage mechanics (CDM) model for multiaxial high cycle fatigue is proposed in which the cyclic plasticity constitutive model has been incorporated in the finite element (FE) framework. T-joint FE simulation of fillet welding is implemented to characterize sequentially coupled three-dimensional (3-D) of thermo-mechanical FE formulation and simulate the welding residual stresses. The high cycle fatigue damage model is then taken account into the fillet weld joints under the various cyclic fatigue load types to calculate the fatigue life considering the residual stresses. The fatigue crack initiation and the propagation in the present model estimated for the total fatigue is compared with the experimental results. The FE results illustrated that the proposed high cycle fatigue damage model in this study could become a powerful tool to effectively predict the fatigue life of the welds. Parametric studies in this work are also demonstrated that the welding residual stresses cannot be ignored in the computation of the fatigue life of welded structures.

Nuclear Structure Physics at GSI - Challenges and Perspectives

Energy Technology Data Exchange (ETDEWEB)

Muenzenberg, G.

1999-12-31

The perspectives at GSI for the exploration of exotic regions with new high-current accelerators and recent technical developments including single-atom decay studies, ultra sensitive {gamma}-spectroscopy, new set-ups for reaction studies at relativistic energies in complete kinematics, heavy ion storage rings, and low-energy heavy-ion-electron colliders will be discussed.

The PRESPEC liquid-hydrogen target for in-beam gamma spectroscopy of exotic nuclei at GSI

International Nuclear Information System (INIS)

Louchart, C.; Gheller, J.M.; Chesny, Ph.; Authelet, G.; Rousse, J.Y.; Obertelli, A.; Boutachkov, P.; Pietri, S.; Ameil, F.; Audirac, L.; Corsi, A.; Dombradi, Z.; Gerl, J.; Gillibert, A.; Korten, W.; Mailleret, C.; Merchan, E.; Nociforo, C.; Pietralla, N.; Ralet, D.

2014-01-01

We report on a new liquid hydrogen and deuterium target dedicated to in-beam γ spectroscopy experiments in inverse kinematics at relativistic incident energies at GSI/FAIR. Target thicknesses from 10 to 80 mm can be achieved for an effective diameter of 60 mm. The target-cell and entrance window are maded of 200μm thick Mylar. The design has the advantage of being free of absorbing material at forward angles and 90°, allowing the detection of photons in a wide angular range. A commissioning experiment with a 54 Cr beam at 130 MeV/nucleon has been performed at GSI, using the Rare Isotopes INvestigation at GSI (RISING) detectors. The target has been shown to behave as expected and is ready for experiments at fragmentation Radioactive-Ion Beam Facilities. -- Highlights: • We report on a new liquid hydrogen target for gamma spectroscopy experiments at FAIR. • A commissioning experiment has been performed at GSI, using the RISING detectors. • The target behaves as expected and is ready for experiments

A Modular VME Data Acquisition System for Counter Applications at the GSI Synchrotron

CERN Document Server

Liakin, D A

2003-01-01

Particle counters perform the control of beam loss and slowly extracted currents at the heavy ion synchrotron (SIS) at GSI. A new VME/Lynx - PC/Linux based data acquisition system has been developed to combine the operating purposes beam loss measurement, spill analysis, spill structure measurement and matrix switching functionality in one single assembly. In this paper a detailed PC-side software description is presented. To achieve best system stability, the software has been divided into time critical networking and data deploying threads and low or normal priority interface tasks. Some new abilities in the fields of data computation and presentation are reported. A hardware description is presented, in detail a programmable GSI-EVENT controller, which is based on an ordinary 8 bit RISC microprocessor and which has been integrated into the system, to synchronize the data acquisition with the sophisticated “virtual accelerator” timing at GSI. First experiences gained while the commission...

Vectra GSI, Inc. low-level waste melter testing Phase 1 test report

Energy Technology Data Exchange (ETDEWEB)

Stegen, G.E.; Wilson, C.N.

1996-02-21

A multiphase program was initiated in 1994 to test commercially available melter technologies for the vitrification of the low-level waste (LLW) stream from defense wastes stored in underground tanks at the Hanford Site in southeastern Washington State. Vectra GSI, Inc. was one of seven vendors selected for Phase 1 of the melter demonstration tests using simulated LLW that were completed during fiscal year 1995. The attached report prepared by Vectra GSI, Inc. describes results of melter testing using slurry feed and dried feeds. Results of feed drying and prereaction tests using a fluid bed calciner and rotary dryer also are described.

Vectra GSI, Inc. low-level waste melter testing Phase 1 test report

International Nuclear Information System (INIS)

Stegen, G.E.; Wilson, C.N.

1996-01-01

A multiphase program was initiated in 1994 to test commercially available melter technologies for the vitrification of the low-level waste (LLW) stream from defense wastes stored in underground tanks at the Hanford Site in southeastern Washington State. Vectra GSI, Inc. was one of seven vendors selected for Phase 1 of the melter demonstration tests using simulated LLW that were completed during fiscal year 1995. The attached report prepared by Vectra GSI, Inc. describes results of melter testing using slurry feed and dried feeds. Results of feed drying and prereaction tests using a fluid bed calciner and rotary dryer also are described

A new standard method for the surveying and alignment of beamline facilities at GSI

Energy Technology Data Exchange (ETDEWEB)

Wirth, H. [Metronom, Gesellschaft fuer Industrievermessung mbH, Mainz (Germany); Moritz, G.

1996-01-01

The GSI institute of heavy ion research is financed by the country of Germany. Founded in 1969, the main emphasis of the institute`s work is the research of the characteristics of atomic nuclei. The Universal Linear Accelerator UNILAC was built first and in 1987 new facilities were added to the setup. The GSI accelarators allow acceleration of all atomic nuclei up to Uranium to an energy of 20 MeV/u. In 1993 Metronome started working on a new alignment concept for the GSI`s accelerators. Metronome has developed the TASA concept. TSAS stands for Techeometric Accelerator Surveying and Alignment and is based on the new generation of high-precision total stations. One feature included in the TASA Concept, has been the replacement of all mobile plates by fixed consoles. An immense advantage of new fixed consoles, welded onto every component, is that they can be positioned to locations where they can be easily measured, simply by taking measuring conditions (lines of sight, heights of stands, error-figures, configuration, etc.) into consideration. The TASA Concept can be used for all alignments of the different GSI accelerators. For all accelerators a special investigation was carried out to check if it is possible to position a new pillar system and to install new consoles on the components. The free positioning of fiducial points makes it possible to use polar measurements for all components. This is an enormous advantage and a step forward for alignment procedures at GSI. Furthermore, use of a total station as opposed to the ECDS System means that one operator less is needed. (S.Y.)

Logging damage to residual trees following commercial harvesting to different overstory retention levels in a mature hardwood stand in Tennessee

Science.gov (United States)

Wayne K. Clatterbuck

2006-01-01

Partial cutting in mature hardwood stands often causes physical damage to residual stems through felling and skidding resulting in a decline in bole quality and subsequent loss of tree value. This study assessed the logging damage to residual trees following commercial harvesting in a fully stocked, mature oak-hickory stand cut to three overstory basal area retention...

Application of Beam Diagnostics for Intense Heavy Ion Beams at the GSI UNILAC

CERN Document Server

Barth, W; Glatz, J; Groening, L; Richter, S; Yaramishev, S

2003-01-01

With the new High Current Injector (HSI) of the GSI UNILAC the beam pulse intensity had been increased by approximately two orders of magnitudes. The HSI was mounted and commissioned in 1999; since this time the UNILAC serves as an injector for the synchrotron SIS, especially for high uranium intensities. Considering the high beam power of up to 1250 kW and the short stopping range for the UNILAC beam energies (≤12 MeV/u), accelerator components could be destroyed, even during a single beam pulse. All diagnostic elements had to be replaced preferably by non-destructive devices. The beam current is mainly measured by beam transformers instead of Faraday cups, beam positions are measured with segmented capacitive pick-ups and secondary beam monitors instead of profile harps. The 24 installed pick-ups are also used to measure intensities, widths and phase of the bunches, as well beam energies by evaluating pick-ups at different positions. The residual gas ionization monitors allow on-line measurements ...

Prevention of damage and 'residual risk' in nuclear power laws

International Nuclear Information System (INIS)

Greipl, C.

1992-01-01

The concept of prevention of damage within the framework of nuclear power laws includes averting danger for the protection of third parties and preventing risks for the partial protection of third parties with the proviso that still a desire to use the concept 'residual risk' in addition, it should be limited, on the grounds of what can be reasonably expected, to those risks which cannot be reduced any further by the government, i.e. to risks which the public in general and third parties ('actually') must accept. In the future, questions regarding safety systems should be taken into account exclusively withing the context of 'what is necessary for protection against damage in keeping with the latest developments in science and technology' and not at the discretion of the law in denying permission according to Article 7 Paragraph 2 Atomic Energy Law. (orig.) [de

Therapy operation at GSI

International Nuclear Information System (INIS)

Scheeler, U.; Wilms, D.

2004-01-01

GSI is the heavy ion research center in Germany operating the three accelerators UNILAC (linac), SIS (synchrotron) and ESR (storage ring). Experiments are made on the fields of nuclear and atomic physics, plasma physics, nuclear chemistry, material research and biophysics. The most important program of the biophysics group is the study of the advantage of Carbon ions for cancer irradiation. The developed raster-scanning technique allows the direct 3D irradiation of irregular shaped tumor and minimizes the dose in healthy tissue [1],[2]. This method requires the reliable request of a large variety of beam parameters (energy, intensity, beam-spot diameter) for sequential synchrotron cycles. Certain restrictions to the physics experimental program have to be considered during the treatment sessions. To deliver excellent conditions for the other experiments, these restrictions had to be kept a small as possible. (author)

The cost system of GSI - heavy ion facility in Darmstadt

International Nuclear Information System (INIS)

1979-01-01

The paper gives an overview about the organization and the research program of the GSI (Heavy Ion Facility in Darmstadt). The cost accounting system is discussed in detail, financing, cost center accounting and cost unit accounting are described. (A.N.)

A SEASONAL COMPARISON OF THE PHYSICAL DAMAGES ON RESIDUAL TREES AND SEEDLINGS DUE TO LOGGING OPERATION USING URUS MIII FOREST SKYLINE IN ARTVIN REGION

OpenAIRE

Habip Eroğlu; Ufuk Özcan Öztürk

2008-01-01

In this paper, the physical damages of logging activities using Urus MIII forest skylines on residual trees and seedlings were evaluated through comparison between harvesting operations took place in winter and summer seasons in Artvin region. In order to achieve our aims, both in winter and summer, 4 representative plots were taken in the harvesting areas using Urus MIII skyline. Physical damages caused by logging to residual trees and seedling were noted. Damage classes for the residual tr...

DEPENDENCIES TO DETERMINE THE MEASURE OF DAMAGE AND CALCULATION OF RESIDUAL LIFE OF REINFORCED CONCRETE SUPERSTRUCTURE, EXPOSED TO SALT CORROSION

OpenAIRE

SAATOVA NODIRA ZIYAYEVNA

2016-01-01

In this paper we consider the current method of determining the measure of damage of concrete and reinforcement. The proposed dependence measures of damage, convenient for use in predicting the life of structures superstructures.The practical method of calculation determination of residual resource of the exploited superstructures developed. The main source of data for calculating the residual life are the parameters defined by the technical diagnosis.

Residual chromosomal damage after radiochemotherapy with and without amifostine detected by 24-color FISH

International Nuclear Information System (INIS)

Kuechler, A.; Wendt, T.G.; Dreidax, M.; Liehr, T.; Claussen, U.; Pigorsch, S.U.; Dunst, J.

2003-01-01

Background: Amifostine is a radioprotective drug applied to reduce acute radiation toxicity during a course of conventionally fractionated radiotherapy. In the present study, amifostine was used in patients undergoing adjuvant radiochemotherapy for rectal cancer. It was described previously that additional application of amifostine led to less acute skin and bowel toxicity. The present study was aimed to determine whether amifostine has an influence on the amount of residual chromosomal damage. Material and Methods: Peripheral lymphocytes of twelve rectal cancer patients who had undergone postoperative radiochemotherapy 2-3 years ago were investigated for residual chromosomal damage using 24-color fluorescence in situ hybridization (24-color FISH). All twelve patients had received a total dose of 55.8 Gy in conventional fractionation of 1.8 Gy and a 120-h continuous infusion of 5-fluorouracil (5-FU) chemotherapy (1,000 mg/m 2 per day) in the 1st and 5th week of irradiation. Seven out of twelve patients had been given additional amifostine on chemotherapy days (500 mg total dose as short i.v. infusion immediately prior to the daily radiation fraction). Cultivation of lymphocytes and 24-color FISH were performed according to standard protocols. 100 metaphases per patient were analyzed for chromosomal aberrations in a blind study. Results: Analysis of the average number of breaks per mitosis (B/M) revealed an increased amount of residual chromosomal damage in the group treated with amifostine (0.65 B/M [0.32-0.97]) as well as in those treated without amifostine (0.76 B/M [0.31-1.25]). Also the average number of cells containing aberrations per 100 analyzed metaphases was similar (with amifostine: 22.1 [13-32] vs. 24.4 [13-35] without amifostine). The aberration types, occurring as simple translocations, reciprocal translocations, breaks, dicentrics, inversions, rings and complex chromosomal rearrangements, did not show any specific accumulation in one or the other

Development and user guide for GSI

International Nuclear Information System (INIS)

Lee, Dong Young; Kim, Jeong Taek; Hwang, In Ku; Ham, Chang Sik; Kwon, Ki Chun.

1997-05-01

ADIOS(Alarm Diagnosis and Integrated Operator Support) is designed to improve the operation performance of the man-machine interface system by giving dynamic alarm priority according to plant situation, and implemented with G2 real-time expert shell. It processes alarm priority in G2 using the plant data which is received from simulator, and sends the processed alarm signals to the alarm tile through TCP/IP communication link. This report includes some experiences about the GSI(G2 Standard Interface) configuration and user programming, and describes about how to build on-line ADIOS system. (author)

Residual strength and crack propagation tests on C-130 airplane center wings with service-imposed fatigue damage

Science.gov (United States)

Snider, H. L.; Reeder, F. L.; Dirkin, W. J.

1972-01-01

Fourteen C-130 airplane center wings, each containing service-imposed fatigue damage resulting from 4000 to 13,000 accumulated flight hours, were tested to determine their fatigue crack propagation and static residual strength characteristics. Eight wings were subjected to a two-step constant amplitude fatigue test prior to static testing. Cracks up to 30 inches long were generated in these tests. Residual static strengths of these wings ranged from 56 to 87 percent of limit load. The remaining six wings containing cracks up to 4 inches long were statically tested as received from field service. Residual static strengths of these wings ranged from 98 to 117 percent of limit load. Damage-tolerant structural design features such as fastener holes, stringers, doublers around door cutouts, and spanwise panel splices proved to be effective in retarding crack propagation.

Evaluation of myocardial damage and cardiac residual capacity by Tl-201 myocardial scintigraphy in valvular heart diseases

International Nuclear Information System (INIS)

Indo, Shunju

1992-01-01

This study was performed to clarify whether the extent-score (Ex-Score) calculated by Tl-201 myocardial scintigraphy is a reliable indicator of the severity of myocardial damage and cardiac residual capacity in valvular heart diseases. The subjects consisted of 38 patients (10 with aortic regurgitation (AR), 4 with aortic stenosis (AS), 13 with mitral regurgitation (MR) and 11 with mitral stenosis (MS)). Ex-Scores were significantly correlated with the severity of myocardial damage found in biopsied specimens obtained intraoperatively (correlation efficiency to Ex-Score with cell diameter in AR, % fibrosis in AR, cell diameter in AS, electron microscopic score in MR and % fibrosis in MS was 0.873, 0.734, 0.970, 0.913 and 0.659, respectively). Ex-Scores were also correlated with cardiac residual capacity determined by radioisotope angiography (correlation efficiency to Ex-Score with %Δ ejection fraction in AR, %Δ end-systolic volume in MR, %Δ end-diastolic volume in MS was -0.764, 0.790 and -0.763, respectively). These results suggest that the severity of myocardial damage and cardiac residual capacity can be estimated by Tl-201 myocardial scintigraphy (Ex-Score) in valvular heart diseases. (author)

Grid Computing at GSI for ALICE and FAIR - present and future

International Nuclear Information System (INIS)

Schwarz, Kilian; Uhlig, Florian; Karabowicz, Radoslaw; Montiel-Gonzalez, Almudena; Zynovyev, Mykhaylo; Preuss, Carsten

2012-01-01

The future FAIR experiments CBM and PANDA have computing requirements that fall in a category that could currently not be satisfied by one single computing centre. One needs a larger, distributed computing infrastructure to cope with the amount of data to be simulated and analysed. Since 2002, GSI operates a tier2 center for ALICE-CERN. The central component of the GSI computing facility and hence the core of the ALICE tier2 centre is a LSF/SGE batch farm, currently split into three subclusters with a total of 15000 CPU cores shared by the participating experiments, and accessible both locally and soon also completely via Grid. In terms of data storage, a 5.5 PB Lustre file system, directly accessible from all worker nodes is maintained, as well as a 300 TB xrootd-based Grid storage element. Based on this existing expertise, and utilising ALICE's middleware ‘AliEn’, the Grid infrastructure for PANDA and CBM is being built. Besides a tier0 centre at GSI, the computing Grids of the two FAIR collaborations encompass now more than 17 sites in 11 countries and are constantly expanding. The operation of the distributed FAIR computing infrastructure benefits significantly from the experience gained with the ALICE tier2 centre. A close collaboration between ALICE Offline and FAIR provides mutual advantages. The employment of a common Grid middleware as well as compatible simulation and analysis software frameworks ensure significant synergy effects.

Review of current literature related to GSI-15

International Nuclear Information System (INIS)

Lipinski, R.E.

1991-01-01

EG and G Idaho is evaluating the structural integrity of Reactor Pressure Vessel Supports as part of its resolution of NRC Generic Safety Issue (GSI) 15, 'Radiation effects on Reactor Vessel Supports'. Structural analyses have been performed by the NRC, ORNL, LLNL, Portland General Electric Co., and several consultants. Two methods of analyses were used. This paper contains a short discussion of the analyses and the merits of the two analysis methods. (author)

Determination of the mechanical parameters of rock mass based on a GSI system and displacement back analysis

Science.gov (United States)

Kang, Kwang-Song; Hu, Nai-Lian; Sin, Chung-Sik; Rim, Song-Ho; Han, Eun-Cheol; Kim, Chol-Nam

2017-08-01

It is very important to obtain the mechanical paramerters of rock mass for excavation design, support design, slope design and stability analysis of the underground structure. In order to estimate the mechanical parameters of rock mass exactly, a new method of combining a geological strength index (GSI) system with intelligent displacment back analysis is proposed in this paper. Firstly, average spacing of joints (d) and rock mass block rating (RBR, a new quantitative factor), surface condition rating (SCR) and joint condition factor (J c) are obtained on in situ rock masses using the scanline method, and the GSI values of rock masses are obtained from a new quantitative GSI chart. A correction method of GSI value is newly introduced by considering the influence of joint orientation and groundwater on rock mass mechanical properties, and then value ranges of rock mass mechanical parameters are chosen by the Hoek-Brown failure criterion. Secondly, on the basis of the measurement result of vault settlements and horizontal convergence displacements of an in situ tunnel, optimal parameters are estimated by combination of genetic algorithm (GA) and numerical simulation analysis using FLAC3D. This method has been applied in a lead-zinc mine. By utilizing the improved GSI quantization, correction method and displacement back analysis, the mechanical parameters of the ore body, hanging wall and footwall rock mass were determined, so that reliable foundations were provided for mining design and stability analysis.

Comparison of Dextran Perfusion and GSI-B4 Isolectin Staining in a Mouse Model of Oxygen-induced Retinopathy.

Science.gov (United States)

Huang, Shaofen; Liang, Jiajian; Yam, Gary Hin-Fai; Lu, Zhihao; Pang, Chi Pui; Chen, Haoyu

2015-06-01

Oxygen-induced retinopathy (OIR) is a robust and widely used animal model for the study of retinal neovascularization (NV). Dextran perfusion and Griffonia simplicifolia isolectin B4 (GSI-B4) staining are two common methods for examining the occurrence and extent of OIR. This study provides a quantitative comparison of the two for OIR detection. At postnatal day 7 (PN7), fifteen C57BL/6J mice were exposed to a 75% hyperoxic condition for 5 days and then returned to room air conditions. At PN17, the mice received intravitreal injection of GSI-B4 Alexa Fluor 568 conjugate. After 10 hours, they were infused with FITC-dextran conjugate via the left ventricle. Retinal flat mounts were photographed by confocal microscopy. Areas with fluorescent signals and the total retinal areas were quantified by Image J software. Both GSI-B4 and dextran detected the peripheral neovascular area. The mean hyper fluorescence area was 0.33 ± 0.14% of whole retinal area determined by GSI-B4 staining and 0.25 ± 0.28% determined by dextran perfusion. The difference between the two measures was 0.08% (95% CI:-0.59%, 0.43%). The Pearson correlation coefficient between the two methods was 0.386,P =0.035. The mean coincidence rates were 14.3 ± 13.4% and 24.9 ± 18.5% for GSI-B4 and dextran staining, respectively. Both methods can complement each other in demonstrating and quantitatively evaluating retinal NV. A poor agreement was found between the two methods; GSI-B4 isolectin was more effective than FITC-dextran perfusion in evaluating the extent of retinal NV in a mouse model of OIR.

ASY-EOS experiment at GSI

Directory of Open Access Journals (Sweden)

Kezzar K.

2012-07-01

Full Text Available The elliptic-flow ratio of neutrons with respect to protons in reactions of neutron rich Heavy-Ion at intermediate energies has been recently proposed as an observable sensitive to the strength of the symmetry term in the nuclear equation of state (EOS at supra-saturation densities. The recent results obtained from the existing FOPI/LAND data for 197Au+197Au collisions at 400 MeV/nucleon in comparison with the UrQMD model allowed a first estimate of the symmetry term of the EOS but suffer from a considerable statistical uncertainty. In order to obtain an improved data set for Au+Au collisions and to extend the study to other systems, a new experiment was carried out at the GSI laboratory by the ASY-EOS collaboration in May 2011.

Future Facility: FAIR at GSI

International Nuclear Information System (INIS)

Rosner, Guenther

2007-01-01

The Facility for Antiproton and Ion Research, FAIR, is a new particle accelerator facility to be built at the GSI site in Germany. The research at FAIR will cover a wide range of topics in nuclear and hadron physics, high density plasma and atomic physics, and applications in condensed matter physics and biology. A 1.1 km circumference double ring of rapidly cycling 100 and 300 Tm synchrotrons, will be FAIR's central accelerator system. It will be used to produce, inter alia, high intensity secondary beams of antiprotons and short-lived radioactive nuclei. A subsequent suite of cooler and storage rings will deliver heavy ion and antiproton beams of unprecedented quality. Large experiments are presently being designed by the NUSTAR, PANDA, PAX, CBM, SPARC, FLAIR, HEDgeHOB and BIOMAT collaborations

Assimilation of NUCAPS Retrieved Profiles in GSI for Unique Forecasting Applications

Science.gov (United States)

Berndt, Emily Beth; Zavodsky, Bradley; Srikishen, Jayanthi; Blankenship, Clay

2015-01-01

Hyperspectral IR profiles can be assimilated in GSI as a separate observation other than radiosondes with only changes to tables in the fix directory. Assimilation of profiles does produce changes to analysis fields and evidenced by: Innovations larger than +/-2.0 K are present and represent where individual profiles impact the final temperature analysis.The updated temperature analysis is colder behind the cold front and warmer in the warm sector. The updated moisture analysis is modified more in the low levels and tends to be drier than the original model background Analysis of model output shows: Differences relative to 13-km RAP analyses are smaller when profiles are assimilated with NUCAPS errors. CAPE is under-forecasted when assimilating NUCAPS profiles, which could be problematic for severe weather forecasting Refining the assimilation technique to incorporate an error covariance matrix and creating a separate GSI module to assimilate satellite profiles may improve results.

The ASY-EOS Experiment at GSI

Directory of Open Access Journals (Sweden)

Russotto P.

2016-01-01

Full Text Available The elliptic-flow ratio of neutrons with respect to protons or light complex particles in reactions of heavy ions at pre-relativistic energies has been proposed as an observable sensitive to the strength of the symmetry term of the nuclear equation of state at supra-saturation densities. In the ASY-EOS experiment at the GSI laboratory, flows of neutrons and light charged particles were measured for 197Au+197Au collisions at 400 MeV/nucleon. Flow results obtained for the Au+Au system, in comparison with predictions of the UrQMD transport model, confirm the moderately soft to linear density dependence of the symmetry energy deduced from the earlier FOPI-LAND data.

Environmental Impacts to Residual Stand Damage due to Logging Operations in Hyrcanian Forest

Directory of Open Access Journals (Sweden)

Meghdad JOURGHOLAMI

2012-08-01

Full Text Available The development of harvesting systems aims to provide physically feasible, economically viable, and environmentally sound solutions. Residual stand-damage data have been collected from a mixed broadleaved stand in Kheyrud area in Hyrcanian forest in the northern of Iran. After the harvesting operations, for all trees, damage to the bole, roots, extent of the damage, wounding patterns, size and distribution was assessed using stratified systematic sampling with a random start and fixed area plots. Results show that wounding occurred on 16.4% of the remaining trees, but the severity of wounding varied significantly by species. Forty-six percent of wounding for all species combined was considered as small size. The greatest average amount of damage, to a bole, occurred along the first 1m up from the ground and also within 3m of the skid trail centerline (86.4%. Gouges were present on 79% of all scars. The stratification of the study unit would effectively improve accuracy of stand damage surveys. Selection of the appropriate method for damage reduction to trees adjacent skid trails was crucial. According to the results, skidding damage cannot be completely avoided in practice. We suggest that the education and the entertainment of the foresters and workers in forest would be enhanced and the injuries could be explained before the harvesting to the workers. In such a way the damages would be less in the future.

Recent developments at the ISOL facility of GSI Darmstadt

CERN Document Server

Roeckl, E; Burkard, K; Döring, J; Grawe, H; Hüller, W; Kirchner, R; Mazzocchi, C; Mukha, I; Plettner, C

2003-01-01

The research programme pursued at the ISOL facility of GSI Darmstadt focuses on the study of decay properties of nuclei along the N congruent with Z line between the double shell closures at sup 5 sup 6 Ni and sup 1 sup 0 sup 0 Sn. In this report, the major scientific achievements obtained in the past two years are reviewed, with particular emphasis being put on the detection techniques.

Logging Damage to Residual Trees Following Partial Cutting in a Green Ash-Sugarberry Stand in the Mississippi Delta

Science.gov (United States)

James S. Meadows

1993-01-01

Partial cutting in bottomland hardwoods to control stand density and species composition sometimes results in logging damage to the lower bole and/or roots of residual trees. If severe, logging damage may lead to a decline in tree vigor, which may subsequently stimulate the production of epicormic branches, causing a decrease in bole quality and an eventual loss in...

Effects of stacking sequence on impact damage resistance and residual strength for quasi-isotropic laminates

Science.gov (United States)

Dost, Ernest F.; Ilcewicz, Larry B.; Avery, William B.; Coxon, Brian R.

1991-01-01

Residual strength of an impacted composite laminate is dependent on details of the damage state. Stacking sequence was varied to judge its effect on damage caused by low-velocity impact. This was done for quasi-isotropic layups of a toughened composite material. Experimental observations on changes in the impact damage state and postimpact compressive performance were presented for seven different laminate stacking sequences. The applicability and limitations of analysis compared to experimental results were also discussed. Postimpact compressive behavior was found to be a strong function of the laminate stacking sequence. This relationship was found to depend on thickness, stacking sequence, size, and location of sublaminates that comprise the impact damage state. The postimpact strength for specimens with a relatively symmetric distribution of damage through the laminate thickness was accurately predicted by models that accounted for sublaminate stability and in-plane stress redistribution. An asymmetric distribution of damage in some laminate stacking sequences tended to alter specimen stability. Geometrically nonlinear finite element analysis was used to predict this behavior.

Impact of 3D Var GSI-ENKF hybrid data assimilation system

Indian Academy of Sciences (India)

1National Centre for Medium Range Weather Forecasting, A-50, Sector-62, Noida, ... with a two-way coupling with an 80 member Ensemble Kalman Filter of .... algorithm in the GSI system using single observa- .... casts of hybrid schemes at 850, 500 and 200 hPa pressure ... NCRWF merged rainfall data using rain gauge.

Impact damage and residual strength analysis of composite panels with bonded stiffeners. [for primary aircraft structures

Science.gov (United States)

Madan, Ram C.; Shuart, Mark J.

1990-01-01

Blade-stiffened, compression-loaded cover panels were designed, manufactured, analyzed, and tested. All panels were fabricated from IM6/1808I interleafed graphite-epoxy. An orthotropic blade stiffener and an orthotropic skin were selected to satisfy the design requirements for an advanced aircraft configuration. All specimens were impact damaged prior to testing. Experimental results were obtained for three- and five-stiffener panels. Analytical results described interlaminar forces caused by impact and predicted specimen residual strength. The analytical results compared reasonably with the experimental results for residual strength of the specimens.

MINIMIZING RESIDUAL STAND DAMAGE AND FELLING COST USING LOWEST POSSIBLE FELLING TECHNIQUE (A case study in one logging company in West Kalimantan

Directory of Open Access Journals (Sweden)

Sona Suhartana

2005-03-01

Full Text Available The implementation of felling technique in logging companies is not yet carried out efficiently and appropriately. Study on the lowest possible felling technique (LPFf is considered  to be important to  reduce residual  stand damage and felling cost. This study was carried out in a logging company in West Kalimantan in 2004. The aim of this study was to  determine the effect of LPFT on residual stand damage and felling cost. Data collected in this research include: residual stand damage, working time, timber  volume, productivity,  efficiency,  stump   height  and  felling cost.  Two categories  data were analyzed with  respect  to  their  possible  differences  using  T-test.    The  result  showed  that  the implementation   of  LPFT  was more advantage impact compared  to   that of  conventional felling technique, which is  indicated by the following factors:  (1  Trees damage decreased 2.96%;  (2 Poles damage decreased 4.75%;  (3 Felling productivity decreased 17.16%; (4 Felling efficiency  increased approximately  3.2%;  (5 Felling cost increased about Rp 327.07 /  m'; and (6 in average stump height was 40.60 cm lower.

Monte Carlo simulations for the shielding of the future high-intensity accelerator facility FAIR at GSI.

Science.gov (United States)

Radon, T; Gutermuth, F; Fehrenbacher, G

2005-01-01

The Gesellschaft für Schwerionenforschung (GSI) is planning a significant expansion of its accelerator facilities. Compared to the present GSI facility, a factor of 100 in primary beam intensities and up to a factor of 10,000 in secondary radioactive beam intensities are key technical goals of the proposal. The second branch of the so-called Facility for Antiproton and Ion Research (FAIR) is the production of antiprotons and their storage in rings and traps. The facility will provide beam energies a factor of approximately 15 higher than presently available at the GSI for all ions, from protons to uranium. The shielding design of the synchrotron SIS 100/300 is shown exemplarily by using Monte Carlo calculations with the FLUKA code. The experimental area serving the investigation of compressed baryonic matter is analysed in the same way. In addition, a dose comparison is made for an experimental area operated with medium energy heavy-ion beams. Here, Monte Carlo calculations are performed by using either heavy-ion primary particles or proton beams with intensities scaled by the mass number of the corresponding heavy-ion beam.

Monte Carlo simulations for the shielding of the future high-intensity accelerator facility fair at GSI

International Nuclear Information System (INIS)

Radon, T.; Gutermuth, F.; Fehrenbacher, G.

2005-01-01

The Gesellschaft fuer Schwerionenforschung (GSI) is planning a significant expansion of its accelerator facilities. Compared to the present GSI facility, a factor of 100 in primary beam intensities and up to a factor of 10,000 in secondary radioactive beam intensities are key technical goals of the proposal. The second branch of the so-called Facility for Antiproton and Ion Research (FAIR) is the production of antiprotons and their storage in rings and traps. The facility will provide beam energies a factor of ∼15 higher than presently available at the GSI for all ions, from protons to uranium. The shielding design of the synchrotron SIS 100/300 is shown exemplarily by using Monte Carlo calculations with the FLUKA code. The experimental area serving the investigation of compressed baryonic matter is analysed in the same way. In addition, a dose comparison is made for an experimental area operated with medium energy heavy-ion beams. Here, Monte Carlo calculations are performed by using either heavy-ion primary particles or proton beams with intensities scaled by the mass number of the corresponding heavy-ion beam. (authors)

Construction and characterization of a laser-driven proton beamline at GSI

Energy Technology Data Exchange (ETDEWEB)

Busold, Simon

2014-05-15

The thesis includes the first experiments with the new 100 TW laser beamline of the PHELIX laser facility at GSI Darmstadt to drive a TNSA (Target Normal Sheath Acceleration) proton source at GSI's Z6 experimental area. At consecutive stages a pulsed solenoid has been applied for beam transport and energy selection via chromatic focusing, as well as a radiofrequency cavity for energy compression of the bunch. This novel laser-driven proton beamline, representing a central experiment of the German national LIGHT collaboration (Laser Ion Generation, Handling and Transport), has been used to create collimated, intense proton bunches at 10 MeV with 2.7% energy spread from the laser-driven source. Also, the feasibility of phase focusing experiments with this setup has been shown and simulations predict peak currents of 10{sup 10} protons/ns at this energy level. Furthermore, first quantitative measurements on the spectral properties of the also present co-moving electrons from such a proton source could be performed and their influence on the protons within the solenoid observed. Finally, permanent magnetic quadrupoles as an alternative first ion collimation system have been investigated experimentally.

INDRA-GSI: Collective flow from Fermi to relativistic energies

Energy Technology Data Exchange (ETDEWEB)

Lukasik, J.; Trautmann, W.; Begemann-Blaich, M.L.; Bittiger, R.; Gourio, D.; Le Fevre, A.; Lynen, U.; Mueller, W.F.J.; Orth, H.; Sfienti, C.; Schwarz, C.; Turzo, K. [Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany); Auger, G.; Bouriquet, B.; Chbihi, A.; Frankland, J.D.; Hudan, S.; Lopez, O. [GANIL, CEA et IN2P3-CNRS, 14 - Caen (France); Borderie, B.; Galichet, E.; Lavaud, F.; Plagnol, E. [Paris-11 Univ., Institut de Physique Nucleaire, IN2P3-CNRS, 91 - Orsay (France); Bellaize, N.; Bocage, F.; Bougault, R.; Durand, D.; Hurst, B.; Steckmeyer, J.C.; Tamain, B.; Vient, E. [Caen Univ., LPC (IN2P3-CNRS/ENSI), 14 - Caen (France); Charvet, J.L.; Dayras, R.; Legrain, R.; Nalpas, L.; Volant, C. [CEA Saclay, Dept. d' Astrophysique, de Physique des Particules, de Physique Nucleaire et de l' Instrumentation Associee (DAPNIA/SPhN), 91- Gif sur Yvette (France); Guinet, D.; Lautesse, P. [Institut de Physique Nucleaire, IN2P3-CNRS et Universite, 69 - Villeurbanne (France); Rosato, E.; Vigilante, M. [INFN, Univ. Federico II, Dipartimento di Scienze Fisiche e Sezione, Napoli (Italy); Saija, A. [Universita and INFN I, Dipartimento di Fisica dell' , Catania (Italy); Trzcinski, A.; Zwieglinski, B. [A. Soltan Institute for Nuclear Studies, Warsaw (Poland); Lukasik, J. [H. Niewodniczanski Institute of Nuclear Physics, Krakow (Poland); Galichet, E. [Conservatoire National des Arts et Metiers, 75 - Paris (France)

2003-07-01

Directed flow for the {sup 197}Au + {sup 197}Au reactions at incident energies between 40 and 150 A*MeV has been measured using the 4{pi} multi-detector INDRA at the GSI facility. In particular, the bombarding energy at which the elliptic flow switches from in-plane to out-of-plane enhancement has been determined to be around 100 A*MeV in good agreement with the result obtained by the FOPI Collaboration. The new data allows also to extend the experimental excitation function of v{sub 2} to lower energies. (authors)

INDRA-GSI: Collective flow from Fermi to relativistic energies

International Nuclear Information System (INIS)

Lukasik, J.; Trautmann, W.; Begemann-Blaich, M.L.; Bittiger, R.; Gourio, D.; Le Fevre, A.; Lynen, U.; Mueller, W.F.J.; Orth, H.; Sfienti, C.; Schwarz, C.; Turzo, K.; Auger, G.; Bouriquet, B.; Chbihi, A.; Frankland, J.D.; Hudan, S.; Lopez, O.; Borderie, B.; Galichet, E.; Lavaud, F.; Plagnol, E.; Bellaize, N.; Bocage, F.; Bougault, R.; Durand, D.; Hurst, B.; Steckmeyer, J.C.; Tamain, B.; Vient, E.; Charvet, J.L.; Dayras, R.; Legrain, R.; Nalpas, L.; Volant, C.; Guinet, D.; Lautesse, P.; Rosato, E.; Vigilante, M.; Saija, A.; Trzcinski, A.; Zwieglinski, B.; Lukasik, J.; Galichet, E.

2003-01-01

Directed flow for the 197 Au + 197 Au reactions at incident energies between 40 and 150 A*MeV has been measured using the 4π multi-detector INDRA at the GSI facility. In particular, the bombarding energy at which the elliptic flow switches from in-plane to out-of-plane enhancement has been determined to be around 100 A*MeV in good agreement with the result obtained by the FOPI Collaboration. The new data allows also to extend the experimental excitation function of v 2 to lower energies. (authors)

Constraining astrophysical reaction rates: using the storage rings at FAIR/GSI

Science.gov (United States)

Langer, Christoph; Glorius, Jan; Slavkovská, Zuzana; Litvinov, Sergey; Litvinov, Yuri A.; Reifarth, René

2018-01-01

Ion optical calculations for a storage ring at the present GSI facility for direct proton-induced reactions relevant for different astrophysical processes are presented. As an example case, the 59Cu(p,γ) and 59Cu(p,α) reactions are shown. The branching of these two reactions is important in X-ray burst scenarios, since it determines the breakout out of the major 56Ni waiting point.

CSF inflammatory biomarkers responsive to treatment in progressive multiple sclerosis capture residual inflammation associated with axonal damage.

Science.gov (United States)

Romme Christensen, Jeppe; Komori, Mika; von Essen, Marina Rode; Ratzer, Rikke; Börnsen, Lars; Bielekova, Bibi; Sellebjerg, Finn

2018-05-01

Development of treatments for progressive multiple sclerosis (MS) is challenged by the lack of sensitive and treatment-responsive biomarkers of intrathecal inflammation. To validate the responsiveness of cerebrospinal fluid (CSF) inflammatory biomarkers to treatment with natalizumab and methylprednisolone in progressive MS and to examine the relationship between CSF inflammatory and tissue damage biomarkers. CSF samples from two open-label phase II trials of natalizumab and methylprednisolone in primary and secondary progressive MS. CSF concentrations of 20 inflammatory biomarkers and CSF biomarkers of axonal damage (neurofilament light chain (NFL)) and demyelination were analysed using electrochemiluminescent assay and enzyme-linked immunosorbent assay (ELISA). In all, 17 natalizumab- and 23 methylprednisolone-treated patients had paired CSF samples. CSF sCD27 displayed superior standardised response means and highly significant decreases during both natalizumab and methylprednisolone treatment; however, post-treatment levels remained above healthy donor reference levels. Correlation analyses of CSF inflammatory biomarkers and NFL before, during and after treatment demonstrated that CSF sCD27 consistently correlates with NFL. These findings validate CSF sCD27 as a responsive and sensitive biomarker of intrathecal inflammation in progressive MS, capturing residual inflammation after treatment. Importantly, CSF sCD27 correlates with NFL, consistent with residual inflammation after anti-inflammatory treatment being associated with axonal damage.

Performance of upstream interaction region detectors for the FIRST experiment at GSI

CERN Document Server

Abou-Haidar, Z; Alvarez, M A G; Anelli, M; Aumann, T; Battistoni, G; Bocci, A; Bohlen, T T; Boudard, A; Brunetti, A; Carpinelli, M; Cirrone, G A P; Cortes-Giraldo, M A; Cuttone, G; De Napoli, M; Durante, M; Fernandez-Garcia, J P; Finck, C; Gallardo, M I; Golosio, B; Iarocci, E; Iazzi, F; Ickert, G; Introzzi, R; Juliani, D; Krimmer, J; Kurz, N; Labalme, M; Leifels, Y; Le Fevre, A; Leray, S; Marchetto, F; Monaco, V; Morone, M C; Oliva, P; Paoloni, A; Patera, V; Piersanti, L; Pleskac, R; Quesada, J M; Randazzo, N; Romano, F; Rossi, D; Rosso, V; Rousseau, M; Sacchi, R; Sala, P; Sarti, A; Schuy, C; Sciubba, A; Sfienti, C; Simon, H; Sipala, V; Spiriti, E; Stuttge, L; Tropea, S; Younis, H

2012-01-01

The FIRST (Fragmentation of Ions Relevant for Space and Therapy) experiment at GSI has been designed to study carbon fragmentation, measuring (12)C double differential cross sections (- (2)I /- - E) for different beam energies between 100 and 1000 MeV/u. The experimental setup integrates newly designed detectors in the, so called, Interaction Region around the graphite target. The Interaction Region upstream detectors are a 250 mum thick scintillator and a drift chamber optimized for a precise measurement of the ions interaction time and position on the target. In this article we review the design of the upstream detectors along with the preliminary results of the data taking performed on August 2011 with 400 MeV/u fully stripped carbon ion beam at GSI. Detectors performances will be reviewed and compared to those obtained during preliminary tests, performed with 500 MeV electrons (at the BTF facility in the INFN Frascati Laboratories) and 80 MeV/u protons and carbon ions (at the INFN LNS Laboratories in Cata...

Residual tissue post splenectomy detected by splenic scintillography with erythrocytes damaged by heat

International Nuclear Information System (INIS)

Rivera B, B.; Garcia C, E.S.; Garcia O, J.R.

2005-01-01

Feminine of 26 years old with diagnostic of purple thrombocytopenic idiopathic to those 4 years of age, tried with steroids and splenectomy at 11 years old. Pathway practically asymptomatic until 4 months ago she had presented asthenia, adynamia and general uneasiness, with platelet figures of 40,000 plat/microliter. It was carried out scintillographic study with damaged erythrocytes for post surgical remainder search. Its were took two-dimensional images and tomography by single photon emission (SPECT), being knitted splenic residual in area of anatomical projection of the spleen. (Author)

Prospects of open charm production at GSI-FAIR and J-PARC

International Nuclear Information System (INIS)

Riedl, J.; Schaefer, A.; Stratmann, M.

2007-01-01

We present a detailed phenomenological study of the prospects of open charm physics at the future pp and pp facilities GSI-FAIR and J-PARC, respectively. In particular, we concentrate on the differential cross sections and the charge and longitudinal double-spin asymmetries at next-to-leading order accuracy. Theoretical uncertainties for the proposed observables are estimated by varying the charm quark mass and the renormalization and factorization scales. (orig.)

Experiments with beams of exotic nuclei at GSI and FAIR

International Nuclear Information System (INIS)

Emling, Hans

2006-01-01

The facility for antiproton and ion research FAIR will provide the international science community with a technically novel and in many respects unique accelerator system for a multi-faceted physics program. Rare-isotope beams of much improved quality together with advanced experimental concepts promise detailed experimental investigations of nuclei far away from stability. A brief description of the rare-isotope beam facility at FAIR is presented, which allows to extend substantially the current successful experimental program with exotic nuclei at GSI. (author)

CARE-HHH-APD Workshop on Finalizing the Roadmap for the Upgrade of the CERN and GSI Accelerator Complex

CERN Document Server

Zimmermann, Frank; BEAM'07; BEAM 2007; Finalizing the Roadmap for the Upgrade of the LHC and GSI Accelerator Complex

2008-01-01

This report contains the Proceedings of the CARE-HHH-APD Event BEAM’07, “Finalizing the Roadmap for the Upgrade of the CERN & GSI Accelerator Complex,” which was held at CERN in Geneva, Switzerland, from 1 to 5 October 2007. BEAM’07 was primarily devoted to beam dynamics limitations for the two, or three, alternative baseline scenarios of the LHC luminosity upgrade and to critical design choices for the upgrade of the LHC injector complex at CERN and for the FAIR complex at GSI. It comprised five parts: (1) a Mini-Workshop on LHC+ Beam Performance, (2) a CERN-GSI Meeting on Collective Effects, (3) the Francesco Ruggiero Memorial Symposium, (4) a Mini-Workshop on the LHC Injectors Upgrade, and (5) the BEAM’07 Summaries. Topics addressed in the first mini-workshop of BEAM’07 ranged from the luminosity performance reach of the upgraded LHC in different scenarios, over the generation and stability of the future LHC beams, the turnaround time, beam–beam effects, luminosity levelling methods, and ...

Upgrading the GSI beamline microscope with a confocal fluorescence lifetime scanner to monitor charged particle induced chromatin decondensation in living cells

Energy Technology Data Exchange (ETDEWEB)

Abdollahi, Elham; Taucher-Scholz, Gisela [Department of Biophysics, GSI Helmholtz Center for Heavy Ion Research, Planckstrasse 1, 64291 Darmstadt (Germany); Durante, Marco [Department of Biophysics, GSI Helmholtz Center for Heavy Ion Research, Planckstrasse 1, 64291 Darmstadt (Germany); Institute for Condensed Matter Physics, Darmstadt University of Technology, 64289 Darmstadt (Germany); Jakob, Burkhard, E-mail: B.Jakob@gsi.de [Department of Biophysics, GSI Helmholtz Center for Heavy Ion Research, Planckstrasse 1, 64291 Darmstadt (Germany)

2015-12-15

We report the upgrade of the GSI beamline microscope coupled to the linear accelerator UNILAC by a confocal FLIM scanner utilizing time correlated single photon counting technique (TCSPC). The system can now be used to address the radiation induced chromatin decondensation in more detail and with higher sensitivity compared to intensity based methods. This decondensation of heterochromatic areas is one of the early DNA damage responses observed after charged particle irradiation and might facilitate the further processing of the induced lesions. We describe here the establishment of different DNA dyes as chromatin compaction probes usable for quantification of the DNA condensation status in living cells utilizing lifetime imaging. In addition, we find an evidence of heterochromatic chromatin decondensation in ion irradiated murine chromocenters detected after subsequent fixation using FLIM measurements.

Isotopic yields and kinetic energies of primary residues in 1 A GeV 208Pb + p reactions

International Nuclear Information System (INIS)

Enqvist, T.; Wlazlo, W.; Armbruster, P.

2000-09-01

The production of primary residual nuclei in the reaction 1 A GeV 208 Pb on proton has been studied by measuring isotopic distributions for all elements from titanium (Z=22) to lead (Z=82). Kinematical properties of the residues were also determined and used to disentangle the relevant reaction mechanisms, spallation (projectile fragmentation) and fission. The fragment separator FRS at GSI, Darmstadt, was used to separate and identify the reaction products. The measured production cross sections are highly relevant for the design of accelerator-driven subcritical reactors and for the planning of future radioactive-beam facilities. (orig.)

Experience with carbon ion radiotherapy at GSI

Energy Technology Data Exchange (ETDEWEB)

Jaekel, O. [Division of Medical Physics in Radiation Therapy (E040), German Cancer Research Center, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg (Germany)]. E-mail: o.jaekel@dkfz.de; Schulz-Ertner, D. [Department of Radiation Oncology, University of Heidelberg, Heidelberg (Germany); Karger, C.P. [Division of Medical Physics in Radiation Therapy (E040), German Cancer Research Center, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg (Germany); Heeg, P. [Division of Medical Physics in Radiation Therapy (E040), German Cancer Research Center, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg (Germany); Debus, J. [Department of Radiation Oncology, University of Heidelberg, Heidelberg (Germany)

2005-12-15

At GSI, a radiotherapy facility was established using beam scanning and active energy variation. Between December 1997 and April 2004, 220 patients have been treated at this facility with carbon ions. Most patients are treated for chordoma and chondrosarcoma of the base of skull, using a dose of 60 Gye (Gray equivalent) in 20 fractions. Carbon ion therapy is also offered in a combination with conventional radiotherapy for a number of other tumors (adenoidcystic carcinoma, chordoma of the cervical spine and sacrum, atypical menningeoma). The patients treated for skull base tumors showed an overall local control rate after two years of 90%. The overall treatment toxicity was mild. This shows that carbon ion radiotherapy can safely be applied using a scanned beam and encouraged the Heidelberg university hospital to build a hospital based facility for ion therapy.

Development and application of an initial quality assurance program for dosimetry at GSI

Energy Technology Data Exchange (ETDEWEB)

Heeg, P; Hartmann, G; Jaekel, O; Karger, C; Kriessbach, A [DKFZ Heidelberg (Germany); Schardt, D [GSI Darmstadt (Germany)

1997-09-01

c set of test procedures has been developed for dosimetric quality inspections at the heavy ion therapy facility at GSI. In some cases new test principles had to be established to meet the requirements at the heavy ion beam. As a first application the acceptance test has been carried out during the technical commissioning of the facility. (orig.)

Analysis of the spallation residues and the associated particles in the reaction Fe+p at 1 GeV per nucleon

International Nuclear Information System (INIS)

Le Gentil, E.

2006-09-01

SPALADIN is a new type of spallation experiment that has been carried out at the GSI accelerator facility (Germany) in order to improve the modelling of the spallation reaction. This experiment is based on the coincidence measurement in inverse kinematics of the spallation residues and the de-excitation fragments. This work presents the analysis of Fe 56 + p reaction at 1 GeV per nucleon. Results on cross-sections and heavy residue velocity spectra are compared to previous data and enabled us to characterize the setup. Most of the element production cross-sections have been obtained with an uncertainty below 10 per cent. In the particular case of helium, its production cross-section has been measured to be σ(1 GeV) = (598 ± 67) mb. The knowledge of this cross-section is important to assess the irradiation damage undergone by the window separating the accelerator from the target. The study of the de-excitation of the pre-fragment shows that the evaporation of light particles (Z ≤ 2) is the main way of de-excitation whatever the collision centrality. However, the de-excitation through the emission of intermediate mass fragments is observed in 5% of the events and most of these events correspond to a very asymmetric binary breaking. The velocity distributions of light residues (with regards to the mass of the projectile) show a significant disagreement with the average velocities predicted by spallation codes. (A.C.)

Nonuniform radiation damage in permanent magnet quadrupoles.

Science.gov (United States)

Danly, C R; Merrill, F E; Barlow, D; Mariam, F G

2014-08-01

We present data that indicate nonuniform magnetization loss due to radiation damage in neodymium-iron-boron Halbach-style permanent magnet quadrupoles. The proton radiography (pRad) facility at Los Alamos uses permanent-magnet quadrupoles for magnifying lenses, and a system recently commissioned at GSI-Darmsdadt uses permanent magnets for its primary lenses. Large fluences of spallation neutrons can be produced in close proximity to these magnets when the proton beam is, intentionally or unintentionally, directed into the tungsten beam collimators; imaging experiments at LANL's pRad have shown image degradation with these magnetic lenses at proton beam doses lower than those expected to cause damage through radiation-induced reduction of the quadrupole strength alone. We have observed preferential degradation in portions of the permanent magnet quadrupole where the field intensity is highest, resulting in increased high-order multipole components.

Nonuniform radiation damage in permanent magnet quadrupoles

International Nuclear Information System (INIS)

Danly, C. R.; Merrill, F. E.; Barlow, D.; Mariam, F. G.

2014-01-01

We present data that indicate nonuniform magnetization loss due to radiation damage in neodymium-iron-boron Halbach-style permanent magnet quadrupoles. The proton radiography (pRad) facility at Los Alamos uses permanent-magnet quadrupoles for magnifying lenses, and a system recently commissioned at GSI-Darmsdadt uses permanent magnets for its primary lenses. Large fluences of spallation neutrons can be produced in close proximity to these magnets when the proton beam is, intentionally or unintentionally, directed into the tungsten beam collimators; imaging experiments at LANL’s pRad have shown image degradation with these magnetic lenses at proton beam doses lower than those expected to cause damage through radiation-induced reduction of the quadrupole strength alone. We have observed preferential degradation in portions of the permanent magnet quadrupole where the field intensity is highest, resulting in increased high-order multipole components

Nonuniform radiation damage in permanent magnet quadrupoles

Energy Technology Data Exchange (ETDEWEB)

Danly, C. R.; Merrill, F. E.; Barlow, D.; Mariam, F. G. [Los Alamos National Laboratory, Los Alamos, New Mexico 87544 (United States)

2014-08-15

We present data that indicate nonuniform magnetization loss due to radiation damage in neodymium-iron-boron Halbach-style permanent magnet quadrupoles. The proton radiography (pRad) facility at Los Alamos uses permanent-magnet quadrupoles for magnifying lenses, and a system recently commissioned at GSI-Darmsdadt uses permanent magnets for its primary lenses. Large fluences of spallation neutrons can be produced in close proximity to these magnets when the proton beam is, intentionally or unintentionally, directed into the tungsten beam collimators; imaging experiments at LANL’s pRad have shown image degradation with these magnetic lenses at proton beam doses lower than those expected to cause damage through radiation-induced reduction of the quadrupole strength alone. We have observed preferential degradation in portions of the permanent magnet quadrupole where the field intensity is highest, resulting in increased high-order multipole components.

Active disease and residual damage in treated Wegener's granulomatosis: an observational study using pulmonary high-resolution computed tomography

International Nuclear Information System (INIS)

Komocsi, Andras; Reuter, Michael; Heller, Martin; Murakoezi, Henriette; Gross, Wolfgang L.; Schnabel, Armin

2003-01-01

The purpose of this study was to determine to what extent high-resolution computed tomography (HRCT) of the lungs can distinguish active inflammatory disease from inactive cicatricial disease in patients treated for Wegener's granulomatosis (WG). Twenty-eight WG patients with active pulmonary disease underwent a first HRCT examination immediately before standard immunosuppressive treatment and a second examination after clinical remission had been achieved. Lesions remaining after treatment were categorized as residual damage and were compared with findings during active disease to see by what features active and cicatricial disease can be distinguished. During active disease 17 patients had nodules/masses, 12 had ground-glass opacities, 6 had septal lines and 6 had non-septal lines. After treatment, ground-glass opacities had resolved completely. Nodules/masses had resolved in 8 patients and had diminished in 7 patients. Residual nodules were distinguished from nodules/masses in active disease by lack of cavitation and a diameter of mostly <15 mm. In one-third of patients lines resolved, but in 8 instances new lines evolved during immunosuppression. During a follow-up period of a median 26.5 months (range 20.0-33.8), patients with residual nodules or lines had no more relapses than patients with completely cleared lungs. Treated pulmonary WG leaves substantial residual damage. High-resolution CT does assist in the distinction between active and inactive lesions. Ground-glass opacities, cavitating nodules/masses and masses measuring more than 3 cm represent active disease ordinarily. Non-cavitary small nodules and septal or non-septal lines can be either active or cicatricial lesions. The nature of these lesions needs to be clarified by longitudinal observation. (orig.)

An alternative window upon the GSI sharp lepton problem

International Nuclear Information System (INIS)

Griffin, J.J.

1997-10-01

Two major heavy ion studies of the GSI ''(e + e - )-Puzzle'' have ended in stalemate: APEX reports no evidence, but its data show a peak near 800 keV. EPOS/II cannot reproduce its own results,and leans towards random fluctuations as the explanation of sharp pair lines. (But one EPOS/II report shows evidence for a peak at an EPOS/I line energy, 610 keV, and under selection conditions the same as EPOSII's.) It is clear that these latest heavy ion studies, designed to settle once and for all the question of sharp pairs, have failed to fulfill that goal. Attention must now turn towards the sharp electron lines reported by Sakai et al. and others in collisions of few MeV beta decay positrons on U and Th atoms. In the Q 0 Scenario of the Sharp Lepton Problem these arise from the same source as the GSI pairs. Verification of Sakai's 100 mb cross section for such sharp electrons in collisions of few MeV electrons (or positrons) upon U or Th atoms would confirm this new experimental window upon the Sharp Lepton Problem. These relatively simple experiments, which are both inexpensive and reproducible (as their heavy ion counterparts are not), promise a less ponderous pace for the study of these questions. On the other hand, they require a challenging combination of proficiencies to measure a nuclear sized cross section in an atomic physics environment. The authors review briefly the diverse history (and especially the most recent developments) of the Sharp Lepton Problem, and outline how the Quadronium Scenario provides it with a unifying conceptual framework. That discussion points clearly towards the experimental study of sharp leptons and sharp pairs from few MeV (lepton+ATOM) and (photon+ATOM) processes as the appropriate next step towards either verifying the earlier results or precluding them

A Green Soundscape Index (GSI): The potential of assessing the perceived balance between natural sound and traffic noise.

Science.gov (United States)

Kogan, Pablo; Arenas, Jorge P; Bermejo, Fernando; Hinalaf, María; Turra, Bruno

2018-06-13

Urban soundscapes are dynamic and complex multivariable environmental systems. Soundscapes can be organized into three main entities containing the multiple variables: Experienced Environment (EE), Acoustic Environment (AE), and Extra-Acoustic Environment (XE). This work applies a multidimensional and synchronic data-collecting methodology at eight urban environments in the city of Córdoba, Argentina. The EE was assessed by means of surveys, the AE by acoustic measurements and audio recordings, and the XE by photos, video, and complementary sources. In total, 39 measurement locations were considered, where data corresponding to 61 AE and 203 EE were collected. Multivariate analysis and GIS techniques were used for data processing. The types of sound sources perceived, and their extents make up part of the collected variables that belong to the EE, i.e. traffic, people, natural sounds, and others. Sources explaining most of the variance were traffic noise and natural sounds. Thus, a Green Soundscape Index (GSI) is defined here as the ratio of the perceived extents of natural sounds to traffic noise. Collected data were divided into three ranges according to GSI value: 1) perceptual predominance of traffic noise, 2) balanced perception, and 3) perceptual predominance of natural sounds. For each group, three additional variables from the EE and three from the AE were applied, which reported significant differences, especially between ranges 1 and 2 with 3. These results confirm the key role of perceiving natural sounds in a town environment and also support the proposal of a GSI as a valuable indicator to classify urban soundscapes. In addition, the collected GSI-related data significantly helps to assess the overall soundscape. It is noted that this proposed simple perceptual index not only allows one to assess and classify urban soundscapes but also contributes greatly toward a technique for separating environmental sound sources. Copyright © 2018 Elsevier B

Insights into location dependent loss-of-coolant-accident (LOCA) frequency assessment for GSI-191 risk-informed applications

Energy Technology Data Exchange (ETDEWEB)

Fleming, K.N., E-mail: KarlFleming@comcast.net [KNF Consulting LLC, Spokane, WA (United States); Lydell, B.O.Y. [SIGMA-PHASE INC., Vail, AZ (United States)

2016-08-15

Highlights: • Role of operating experience in loss-of-coolant-accident (LOCA) frequency assessment. • Plant-to-plant variability in calculated LOCA frequency. • Frequency of double-ended-guillotine-break (DEGB). • Uncertainties in LOCA frequencies. • Risk management insights. - Abstract: As a tribute to the published work by S.H. Bush, S. Beliczey and H. Schulz, this paper assesses the progress with methods and techniques for quantifying the reliability of piping systems in commercial nuclear power plants on the basis of failure rate estimates derived from field experience data in combination with insights and results from probabilistic fracture mechanics analyses and expert elicitation exercises. This status assessment is made from a technical perspective obtained through development of location-specific loss-of-coolant-accident (LOCA) frequencies for input to risk-informed resolution of the generic safety issue (GSI) 191. The methods and techniques on which these GSI-191 applications are based build on a body of work developed by the authors during a period spanning more than two decades. The insights that are presented and discussed in this paper cover today’s knowledge base concerning how to utilize a risk-informed approach to the assessment of piping reliability in the context of probabilistic risk assessment (PRA) in general and the resolution of GSI-191 in particular. Specifically the paper addresses the extent to which LOCA frequencies vary from location to location within a reactor coolant system pressure boundary (RCPB) for a given plant as well as vary from plant to plant, and the reasons for these variabilities. Furthermore, the paper provides the authors’ perspectives on interpretations and applications of information extracted from an expert elicitation process to obtain LOCA frequencies as documented in NUREG-1829 and how to apply this information to GSI-191. Finally, this paper documents technical insights relative to mitigation of

Insights into location dependent loss-of-coolant-accident (LOCA) frequency assessment for GSI-191 risk-informed applications

International Nuclear Information System (INIS)

Fleming, K.N.; Lydell, B.O.Y.

2016-01-01

Highlights: • Role of operating experience in loss-of-coolant-accident (LOCA) frequency assessment. • Plant-to-plant variability in calculated LOCA frequency. • Frequency of double-ended-guillotine-break (DEGB). • Uncertainties in LOCA frequencies. • Risk management insights. - Abstract: As a tribute to the published work by S.H. Bush, S. Beliczey and H. Schulz, this paper assesses the progress with methods and techniques for quantifying the reliability of piping systems in commercial nuclear power plants on the basis of failure rate estimates derived from field experience data in combination with insights and results from probabilistic fracture mechanics analyses and expert elicitation exercises. This status assessment is made from a technical perspective obtained through development of location-specific loss-of-coolant-accident (LOCA) frequencies for input to risk-informed resolution of the generic safety issue (GSI) 191. The methods and techniques on which these GSI-191 applications are based build on a body of work developed by the authors during a period spanning more than two decades. The insights that are presented and discussed in this paper cover today’s knowledge base concerning how to utilize a risk-informed approach to the assessment of piping reliability in the context of probabilistic risk assessment (PRA) in general and the resolution of GSI-191 in particular. Specifically the paper addresses the extent to which LOCA frequencies vary from location to location within a reactor coolant system pressure boundary (RCPB) for a given plant as well as vary from plant to plant, and the reasons for these variabilities. Furthermore, the paper provides the authors’ perspectives on interpretations and applications of information extracted from an expert elicitation process to obtain LOCA frequencies as documented in NUREG-1829 and how to apply this information to GSI-191. Finally, this paper documents technical insights relative to mitigation of

An analytical method to assess the damage and predict the residual strength of a ship in a shoal grounding accident scenario

Directory of Open Access Journals (Sweden)

Sun Bin

2016-04-01

Full Text Available In this paper, a simplified analytical method used to predict the residual ultimate strength of a ship hull after a shoal grounding accident is proposed. Shoal grounding accidents always lead to severe denting, though not tearing, of the ship bottom structure, which may threaten the global hull girder resistance and result in even worse consequences, such as hull collapse. Here, the degree of damage of the bottom structure is predicted by a series of analytical methods based on the plastic-elastic deformation mechanism. The energy dissipation of a ship bottom structure is obtained from individual components to determine the sliding distance of the seabed obstruction. Then, a new approach to assess the residual strength of the damaged ship subjected to shoal grounding is proposed based on the improved Smith's method. This analytical method is verified by comparing the results of the proposed method and those generated by numerical simulation using the software ABAQUS. The proposed analytical method can be used to assess the safety of a ship with a double bottom during its design phase and predict the residual ultimate strength of a ship after a shoal grounding accident occurs.

Conceptualizing a Genomics Software Institute (GSI).

Science.gov (United States)

Gilbert, Jack A; Catlett, Charlie; Desai, Narayan; Knight, Rob; White, Owen; Robbins, Robert; Sankaran, Rajesh; Sansone, Susanna-Assunta; Field, Dawn; Meyer, Folker

2012-03-19

Microbial ecology has been enhanced greatly by the ongoing 'omics revolution, bringing half the world's biomass and most of its biodiversity into analytical view for the first time; indeed, it feels almost like the invention of the microscope and the discovery of the new world at the same time. With major microbial ecology research efforts accumulating prodigious quantities of sequence, protein, and metabolite data, we are now poised to address environmental microbial research at macro scales, and to begin to characterize and understand the dimensions of microbial biodiversity on the planet. What is currently impeding progress is the need for a framework within which the research community can develop, exchange and discuss predictive ecosystem models that describe the biodiversity and functional interactions. Such a framework must encompass data and metadata transparency and interoperation; data and results validation, curation, and search; application programming interfaces for modeling and analysis tools; and human and technical processes and services necessary to ensure broad adoption. Here we discuss the need for focused community interaction to augment and deepen established community efforts, beginning with the Genomic Standards Consortium (GSC), to create a science-driven strategic plan for a Genomic Software Institute (GSI).

The FIRST experiment at GSI

International Nuclear Information System (INIS)

Pleskac, R.; Abou-Haidar, Z.; Agodi, C.; Alvarez, M.A.G.; Aumann, T.; Battistoni, G.; Bocci, A.; Böhlen, T.T.; Boudard, A.; Brunetti, A.; Carpinelli, M.; Cirrone, G.A.P.; Cortes-Giraldo, M.A.; Cuttone, G.; De Napoli, M.; Durante, M.; Fernández-García, J.P.; Finck, C.; Golosio, B.; Gallardo, M.I.

2012-01-01

The FIRST (Fragmentation of Ions Relevant for Space and Therapy) experiment at the SIS accelerator of GSI laboratory in Darmstadt has been designed for the measurement of ion fragmentation cross-sections at different angles and energies between 100 and 1000 MeV/nucleon. Nuclear fragmentation processes are relevant in several fields of basic research and applied physics and are of particular interest for tumor therapy and for space radiation protection applications. The start of the scientific program of the FIRST experiment was on summer 2011 and was focused on the measurement of 400 MeV/nucleon 12 C beam fragmentation on thin (8 mm) graphite target. The detector is partly based on an already existing setup made of a dipole magnet (ALADiN), a time projection chamber (TP-MUSIC IV), a neutron detector (LAND) and a time of flight scintillator system (TOFWALL). This pre-existing setup has been integrated with newly designed detectors in the Interaction Region, around the carbon target placed in a sample changer. The new detectors are a scintillator Start Counter, a Beam Monitor drift chamber, a silicon Vertex Detector and a Proton Tagger scintillator system optimized for the detection of light fragments emitted at large angles. In this paper we review the experimental setup, then we present the simulation software, the data acquisition system and finally the trigger strategy of the experiment.

The FIRST experiment at GSI

Energy Technology Data Exchange (ETDEWEB)

Pleskac, R. [GSI Helmholtzzentrum fuer Schwerionenforschung, Darmstadt (Germany); Abou-Haidar, Z. [CNA, Sevilla (Spain); Agodi, C. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali del Sud (Italy); Alvarez, M.A.G. [CNA, Sevilla (Spain); Aumann, T. [GSI Helmholtzzentrum fuer Schwerionenforschung, Darmstadt (Germany); Battistoni, G. [Istituto Nazionale di Fisica Nucleare - Sezione di Milano (Italy); Bocci, A. [CNA, Sevilla (Spain); Boehlen, T.T. [European Organization for Nuclear Research CERN, Geneva (Switzerland); Medical Radiation Physics, Karolinska Institutet and Stockholm University, Stockholm (Sweden); Boudard, A. [CEA-Saclay, IRFU/SPhN, Gif sur Yvette Cedex (France); Brunetti, A.; Carpinelli, M. [Istituto Nazionale di Fisica Nucleare - Sezione di Cagliari (Italy); Universita' di Sassari (Italy); Cirrone, G.A.P. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali del Sud (Italy); Cortes-Giraldo, M.A. [Departamento de Fisica Atomica, Molecular y Nuclear, University of Sevilla, 41080-Sevilla (Spain); Cuttone, G. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali del Sud (Italy); De Napoli, M. [Istituto Nazionale di Fisica Nucleare - Sezione di Catania (Italy); Durante, M. [GSI Helmholtzzentrum fuer Schwerionenforschung, Darmstadt (Germany); Fernandez-Garcia, J.P. [Departamento de Fisica Atomica, Molecular y Nuclear, University of Sevilla, 41080-Sevilla (Spain); Finck, C. [Institut Pluridisciplinaire Hubert Curien, Strasbourg (France); Golosio, B. [Istituto Nazionale di Fisica Nucleare - Sezione di Cagliari (Italy); Universita' di Sassari (Italy); Gallardo, M.I. [Departamento de Fisica Atomica, Molecular y Nuclear, University of Sevilla, 41080-Sevilla (Spain); and others

2012-06-21

The FIRST (Fragmentation of Ions Relevant for Space and Therapy) experiment at the SIS accelerator of GSI laboratory in Darmstadt has been designed for the measurement of ion fragmentation cross-sections at different angles and energies between 100 and 1000 MeV/nucleon. Nuclear fragmentation processes are relevant in several fields of basic research and applied physics and are of particular interest for tumor therapy and for space radiation protection applications. The start of the scientific program of the FIRST experiment was on summer 2011 and was focused on the measurement of 400 MeV/nucleon {sup 12}C beam fragmentation on thin (8 mm) graphite target. The detector is partly based on an already existing setup made of a dipole magnet (ALADiN), a time projection chamber (TP-MUSIC IV), a neutron detector (LAND) and a time of flight scintillator system (TOFWALL). This pre-existing setup has been integrated with newly designed detectors in the Interaction Region, around the carbon target placed in a sample changer. The new detectors are a scintillator Start Counter, a Beam Monitor drift chamber, a silicon Vertex Detector and a Proton Tagger scintillator system optimized for the detection of light fragments emitted at large angles. In this paper we review the experimental setup, then we present the simulation software, the data acquisition system and finally the trigger strategy of the experiment.

The FIRST experiment at GSI

Science.gov (United States)

Pleskac, R.; Abou-Haidar, Z.; Agodi, C.; Alvarez, M. A. G.; Aumann, T.; Battistoni, G.; Bocci, A.; Böhlen, T. T.; Boudard, A.; Brunetti, A.; Carpinelli, M.; Cirrone, G. A. P.; Cortes-Giraldo, M. A.; Cuttone, G.; De Napoli, M.; Durante, M.; Fernández-García, J. P.; Finck, C.; Golosio, B.; Gallardo, M. I.; Iarocci, E.; Iazzi, F.; Ickert, G.; Introzzi, R.; Juliani, D.; Krimmer, J.; Kurz, N.; Labalme, M.; Leifels, Y.; Le Fevre, A.; Leray, S.; Marchetto, F.; Monaco, V.; Morone, M. C.; Oliva, P.; Paoloni, A.; Piersanti, L.; Quesada, J. M.; Raciti, G.; Randazzo, N.; Romano, F.; Rossi, D.; Rousseau, M.; Sacchi, R.; Sala, P.; Sarti, A.; Scheidenberger, C.; Schuy, C.; Sciubba, A.; Sfienti, C.; Simon, H.; Sipala, V.; Spiriti, E.; Stuttge, L.; Tropea, S.; Younis, H.; Patera, V.

2012-06-01

The FIRST (Fragmentation of Ions Relevant for Space and Therapy) experiment at the SIS accelerator of GSI laboratory in Darmstadt has been designed for the measurement of ion fragmentation cross-sections at different angles and energies between 100 and 1000 MeV/nucleon. Nuclear fragmentation processes are relevant in several fields of basic research and applied physics and are of particular interest for tumor therapy and for space radiation protection applications. The start of the scientific program of the FIRST experiment was on summer 2011 and was focused on the measurement of 400 MeV/nucleon 12C beam fragmentation on thin (8 mm) graphite target. The detector is partly based on an already existing setup made of a dipole magnet (ALADiN), a time projection chamber (TP-MUSIC IV), a neutron detector (LAND) and a time of flight scintillator system (TOFWALL). This pre-existing setup has been integrated with newly designed detectors in the Interaction Region, around the carbon target placed in a sample changer. The new detectors are a scintillator Start Counter, a Beam Monitor drift chamber, a silicon Vertex Detector and a Proton Tagger scintillator system optimized for the detection of light fragments emitted at large angles. In this paper we review the experimental setup, then we present the simulation software, the data acquisition system and finally the trigger strategy of the experiment.

The EXL experiment at FAIR and plans with the ESR at GSI

International Nuclear Information System (INIS)

Kalantar-Nayestanaki, N.

2011-01-01

In this contribution, the physics program of the EXL experiment at FAIR-NuSTAR along with its experimental setup will be briefly outlined. This experiment aims to study the structure and the dynamics of radioactive nuclei which collide with light ions in inverse kinematics. On the way to the final measurements, several measurements have been proposed at the existing ESR at GSI with the purpose of understanding the detection systems for EXL and obtaining the first physics results in this type of experiments in a storage ring.

Residual tissue post splenectomy detected by splenic scintillography with erythrocytes damaged by heat; Tejido residual postesplenectomia detectado por centellografia esplenica con eritrocitos danados por calor

Energy Technology Data Exchange (ETDEWEB)

Rivera B, B; Garcia C, E S; Garcia O, J R [Centro Medico ABC, Departamento de Medicina Nuclear, Mexico, D.F. (Mexico)

2005-07-01

Feminine of 26 years old with diagnostic of purple thrombocytopenic idiopathic to those 4 years of age, tried with steroids and splenectomy at 11 years old. Pathway practically asymptomatic until 4 months ago she had presented asthenia, adynamia and general uneasiness, with platelet figures of 40,000 plat/microliter. It was carried out scintillographic study with damaged erythrocytes for post surgical remainder search. Its were took two-dimensional images and tomography by single photon emission (SPECT), being knitted splenic residual in area of anatomical projection of the spleen. (Author)

GSI papers presented at the 3. European particle accelerator conference

International Nuclear Information System (INIS)

1992-04-01

This report contains the articles presented by the GSI at the named conference. These concern an ion source for heavy ion synchrotron injection, a power amplifier, the new heavy ion injector of the UNILAC, the heavy ion synchrotron SIS, beam intensity measurements at the SIS, heavy ion storage rings, the performance and impedances and instability studies at the ESR, longitudinal space-charge effects in cooled bunched beams, the ERS electron cooling device, experiments with synthetic colored noise at the ESR, ion beams for heavy ion fusion research, a reactor driver concept for indirect drive, plasma lenses for heavy-ion beam focusing, synchrotrons for cancer therapy, and future accelerator projects in collaboration with industry. (orig.)

Tune measurement at GSI SIS-18. Methods and applications

Energy Technology Data Exchange (ETDEWEB)

Singh, Rahul

2014-05-15

Two parallel tune measurement systems are installed at GSI SIS-18 based on different principles. The first is called the Tune, Orbit and POSition measurement system TOPOS. Its working principle involves direct digitization of BPM signals at 125 MSa/s, which is used for online bunch-by-bunch position calculation in FPGAs. In the course of this work, position calculation algorithms were developed and studied for real time implementation in the TOPOS FPGAs. The regression fit algorithm is found to be more efficient and robust in comparison to previously used weighted mean algorithm with the baseline restoration procedure. The second system is the Baseband Tune measurement system referred to as BBQ system. The operational principle of this system was conceived at the CERN Beam Instrumentation group and is based on direct diode detection. In the framework of this work, this system was optimized and brought into operation at GSI SIS-18. Front-end data from both systems are used to calculate the tune spectrum every 250-5000 beam revolutions or turns within SIS-18 based on the resolution requirement and the mode of operation. Advanced non-parametric spectrum estimation method like amplitude Capon estimator is compared to the conventional DFT based methods in terms of resolving power and computational requirements for the calculated spectrum. Further the TOPOS and BBQ systems are compared and characterized in terms of sensitivity, reliability and operational usage. The results from both systems are found to be consistent with each other and have their favoured regimes of operation. The effects on tune spectra obtained from both systems were studied with different types of excitations with excitation power levels up to 6 mW/Hz. These systems in association with other beam diagnostic devices at SIS-18 were used to conduct extensive experiments to understand the effect of high intensity beams on the tune spectrum. These careful measurements recorded all the relevant beam

Isotopic production cross sections of fission residues in 197Au-on-proton collisions at 800 A MeV

International Nuclear Information System (INIS)

Benlliure, J.; Armbruster, P.; Bernas, M.

2000-02-01

Interactions of 197 Au projectiles at 800 A MeV with protons leading to fission are investigated. We measured the production cross sections and velocities of all fission residues which are fully identified in atomic and mass number by using the in-flight separator FRS at GSI. The new data are compared with partial measurements of the characteristics of fission in similar reactions. Both the production cross sections and the recoil energies are relevant for a better understanding of spallation reactions. (orig.)

Cellular radiosensitivity and DNA damage in primary human fibroblasts

International Nuclear Information System (INIS)

Wurm, R.; Burnet, N.G.; Duggal, N.

1994-01-01

To evaluate the relationship between radiation-induced cell survival and DNA damage in primary human fibroblasts to decide whether the initial or residual DNA damage levels are more predictive of normal tissue cellular radiosensitivity. Five primary human nonsyndromic and two primary ataxia telangiectasia fibroblast strains grown in monolayer were studied. Cell survival was assessed by clonogenic assay. Irradiation was given at high dose rate (HDR) 1-2 Gy/min. DNA damage was measured in stationary phase cells and expressed as fraction released from the well by pulsed-field gel electrophoresis (PFGE). For initial damage, cells were embedded in agarose and irradiated at HDR on ice. Residual DNA damage was measured in monolayer by allowing a 4-h repair period after HDR irradiation. Following HDR irradiation, cell survival varied between SF 2 0.025 to 0.23. Measurement of initial DNA damage demonstrated linear induction up to 30 Gy, with small differences in the slope of the dose-response curve between strains. No correlation between cell survival and initial damage was found. Residual damage increased linearly up to 80 Gy with a variation in slope by a factor of 3.2. Cell survival correlated with the slope of the dose-response curves for residual damage of the different strains (p = 0.003). The relationship between radiation-induced cell survival and DNA damage in primary human fibroblasts of differing radiosensitivity is closest with the amount of DNA damage remaining after repair. If assays of DNA damage are to be used as predictors of normal tissue response to radiation, residual DNA damage provides the most likely correlation with cell survival. 52 refs., 5 figs., 2 tabs

Upgrade of the GSI-Unilac as a FAIR high current injector

Energy Technology Data Exchange (ETDEWEB)

Haehnel, Hendrik [Institut fuer Angewandte Physik, Goethe Universitaet Frankfurt (Germany)

2016-07-01

The existing UNIversal Linear Accelerator (UNILAC) at GSI will serve as ion and dedicated uranium ion injector for the Facility for Antiproton and Ion Research (FAIR). For nominal FAIR operation, 15 emA of Uranium 28+ at low emittances have to be injected by multiturn-injection into FAIR. To meet these requirements and to ensure reliable operation, the UNILAC will undergo a significant upgrade process. Upgrade measures concerning key accelerator components are described and a main focus is put on a replacement of the 54m Alvarez-section by a compact IH-DTL. This will open new options for future injection schemes into SIS100.

NASA SPoRT Modeling and Data Assimilation Research and Transition Activities Using WRF, LIS and GSI

Science.gov (United States)

Case, Jonathan L.; Blankenship, Clay B.; Zavodsky, Bradley T.; Srikishen, Jayanthi; Berndt, Emily B.

2014-01-01

weather research and forecasting ===== The NASA Short-term Prediction Research and Transition (SPoRT) program has numerous modeling and data assimilation (DA) activities in which the WRF model is a key component. SPoRT generates realtime, research satellite products from the MODIS and VIIRS instruments, making the data available to NOAA/NWS partners running the WRF/EMS, including: (1) 2-km northwestern-hemispheric SST composite, (2) daily, MODIS green vegetation fraction (GVF) over CONUS, and (3) NASA Land Information System (LIS) runs of the Noah LSM over the southeastern CONUS. Each of these datasets have been utilized by specific SPoRT partners in local EMS model runs, with select offices evaluating the impacts using a set of automated scripts developed by SPoRT that manage data acquisition and run the NCAR Model Evaluation Tools verification package. SPoRT is engaged in DA research with the Gridpoint Statistical Interpolation (GSI) and Ensemble Kalman Filter in LIS for soil moisture DA. Ongoing DA projects using GSI include comparing the impacts of assimilating Atmospheric Infrared Sounder (AIRS) radiances versus retrieved profiles, and an analysis of extra-tropical cyclones with intense non-convective winds. As part of its Early Adopter activities for the NASA Soil Moisture Active Passive (SMAP) mission, SPoRT is conducting bias correction and soil moisture DA within LIS to improve simulations using the NASA Unified-WRF (NU-WRF) for both the European Space Agency's Soil Moisture Ocean Salinity and upcoming SMAP mission data. SPoRT has also incorporated real-time global GVF data into LIS and WRF from the VIIRS product being developed by NOAA/NESDIS. This poster will highlight the research and transition activities SPoRT conducts using WRF, NU-WRF, EMS, LIS, and GSI.

The GSI plans for an international accelerator facility for beams of ions and antiprotons

International Nuclear Information System (INIS)

Suemmerer, K.

2003-01-01

GSI proposes to build a next-generation facility for research with relativistic beams of ions and antiprotons. This facility allows a broad range of topics in nuclear and astrophysics, plasma and atomic physics to be addressed. The topic most interesting in the context of this conference is physics with high-intensity beams of exotic nuclei. In addition, a short overview of the opportunities in the other fields of nuclear physics is given

Comparison of residual strength-grounding damage index diagrams for tankers produced by the ALPS/HULL ISFEM and design formula method

Directory of Open Access Journals (Sweden)

Do Kyun Kim

2013-03-01

Full Text Available This study compares the Residual ultimate longitudinal strength – grounding Damage index (R-D diagrams produced by two analysis methods: the ALPS/HULL Intelligent Supersize Finite Element Method (ISFEM and the design formula (modified Paik and Mansour method – used to assess the safety of damaged ships. The comparison includes four types of double-hull oil tankers: Panamax, Aframax, Suezmax and VLCC. The R-D diagrams were calculated for a series of 50 grounding scenarios. The diagrams were efficiently sampled using the Latin Hypercube Sampling (LHS technique and comprehensively analysed based on ship size. Finally, the two methods were compared by statistically analysing the differences between their grounding damage indices and ultimate longitudinal strength predictions. The findings provide a useful example of how to apply the ultimate longitudinal strength analysis method to grounded ships.

Recent progress in multichamber deposition of high-quality amorphous silicon solar cells on planar and compound curved substrates at GSI

Energy Technology Data Exchange (ETDEWEB)

Schropp, R.E.I.; Roedern, B. von; Klose, P.; Hollingsworth, R.E.; Xi, J.; Cueto, J. del; Chatham, H.; Bhat, P.K. (Glasstech Solar, Inc. (GSI), Wheat Ridge, CO (USA))

1989-10-15

We present recent advances obtained at GSI in scaling-up multichamber fabrication of solar cells. We have successfully adopted the multichamber approach in the development of large-area compound curved semitransparent modules. For this application, a new semitransparent electrode was developed, together with an innovative three-dimensional laser patterning technique. A fully automated 1.5 MW annual production line with a ''glass-in-panel-out'' approach has been completed for the Government of India, and another 3 MW plant is presently under construction. GSI's research effort using its multichamber R and D system has achieved single-junction conversion efficiencies of 11.3% at low intrinsic layer deposition rates and of 9.7% at a rate of 18 A s{sup -1}. (orig.).

GSI Quantitative Parameters: Preoperative Diagnosis of Metastasis Lymph Nodes in Lung Cancer

Directory of Open Access Journals (Sweden)

Fengfeng YANG

2016-11-01

Full Text Available Background and objective Mediastinal involvement in lung cancer is an important prognostic factor affecting survival, and accurate staging of the mediastinum lymph node correctly identifies patients who can benefit the most from surgery. The aim of this study is to investigate the value of dual-energy spectral computed tomography (DEsCT imaging in differentiating metastatic from non-metastatic lymph nodes in lung cancer. Methods Forty-eight patients with non-small cell lung cancer (NSCLC underwent arterial (AP and portal venous (PP phase contrast-enhanced DEsCT imaging followed by surgical treatment. gemstone spectral imaging (GSI data images were reconstructed and transmitted to an offline workstation. GSI quantitative parameters, including lymph-node size, CT value, IC, water concentration, and spectral curve. Differences were tested for statistical significance using the two-sample t test. ROC analysis was performed to assess diagnostic performance. Results The mean short-axis diameter of metastatic LNs, slope of the spectral Hounsfield unit curve (λHU, normalized iodine concentration measured during, and both AP and PP were significantly higher in metastatic lymph node than that in benign lymph nodes. The best parameter for detecting metastatic lymph nodes was AP λHU when a threshold λHU of 2.75 was used; sensitivity, specificity, and accuracy were 88.2%, 88.4%, and 87.0%, respectively. Conclusion Quantitative assessment with gemstone spectral imaging quantitative parameters showed higher accuracy than the qualitative assessment of conventional CT imaging features for the preoperative diagnosis of metastatic lymph nodes in patients with lung cancer.

The SIS-ESR project of GSI

International Nuclear Information System (INIS)

Kienle, P.

1985-05-01

During the last years GSI developed plans for future accelerators and experimental facilities with the intention to extend heavy ion research in a wide scope to higher energies and into new fields of research using novel techniques for acceleration, accumulation, storage and phase space density increase of heavy ion beams up to 238 U. The prime goals of this development plan using as a first step a synchrotron acceleration ring connected with an accumulator-, storage-, cooling- and experimental ring are the following: 1. Provide completely stripped heavy ion beams up to U 92+ with the highest phase space densities using various cooling techniques in a storage ring. 2. Provide radioactive heavy ion beams by accumulation, storage and cooling of fragmentation or fission products from beams of the synchrotron. 3. Provide facilities for internal target experiments using simultaneously cooled circulating beams. 4. Provide two merging beams in the storage ring with well defineable collision energies up to the Coulomb barrier of the heaviest ions like U 92+ in order to study atomic collision processes in high Coulomb fields with both nuclei highly ionized. 5. Provide a beam of heavy ions up to U 92+ with best phase space density for further acceleration and collisions in superconducting collider rings at very high c.m. energies (>20 GeV/u) and as high as possible luminosities. (orig.)

Highly charged ions at rest: The HITRAP project at GSI

International Nuclear Information System (INIS)

Herfurth, F.; Beier, T.; Dahl, L.; Eliseev, S.; Heinz, S.; Kester, O.; Kluge, H.-J.; Kozhuharov, C.; Maero, G.; Quint, W.

2005-01-01

A decelerator will be installed at GSI in order to provide and study bare heavy nuclei or heavy nuclei with only few electrons at very low energies or even at rest. Highly-charged ions will be produced by stripping at relativistic energies. After electron cooling and deceleration in the Experimental Storage Ring the ions are ejected out of the storage ring at 4 MeV/u and further decelerated in a combination of an IH and RFQ structure. Finally, they are injected into a Penning trap where the ions are cooled to 4 K. From here, the ions can be transferred in a quasi dc or in a pulsed mode to different experimental setups. This article describes the technical concepts of this project as well as planned key experiments

Damage accumulation in ceramics during ion implantation

International Nuclear Information System (INIS)

McHargue, C.J.; Farlow, G.C.; Begun, G.M.; Williams, J.M.; White, C.W.; Appleton, B.R.; Sklad, P.S.; Angelini, P.

1985-01-01

The damage structures of α-Al 2 O 3 and α-SiC were examined as functions of ion implantation parameters using Rutherford backscattering-channeling, analytical electron microscopy, and Raman spectroscopy. Low temperatures or high fluences of cations favor formation of the amorphous state. At 300 0 K, mass of the bombarding species has only a small effect on residual damage, but certain ion species appear to stabilize the damage microstructure and increase the rate of approach to the amorphous state. The type of chemical bonding present in the host lattice is an important factor in determining the residual damage state

Preterm newborns show slower repair of oxidative damage and paternal smoking associated DNA damage.

Science.gov (United States)

Vande Loock, Kim; Ciardelli, Roberta; Decordier, Ilse; Plas, Gina; Haumont, Dominique; Kirsch-Volders, Micheline

2012-09-01

Newborns have to cope with hypoxia during delivery and a sudden increase in oxygen at birth. Oxygen will partly be released as reactive oxygen species having the potential to cause damage to DNA and proteins. In utero, increase of most (non)-enzymatic antioxidants occurs during last weeks of gestation, making preterm neonates probably more sensitive to oxidative stress. Moreover, it has been hypothesized that oxidative stress might be the common etiological factor for certain neonatal diseases in preterm infants. The aim of this study was to assess background DNA damage; in vitro H(2)O(2) induced oxidative DNA damage and repair capacity (residual DNA damage) in peripheral blood mononucleated cells from 25 preterm newborns and their mothers. In addition, demographic data were taken into account and repair capacity of preterm was compared with full-term newborns. Multivariate linear regression analysis revealed that preterm infants from smoking fathers have higher background DNA damage levels than those from non-smoking fathers, emphasizing the risk of paternal smoking behaviour for the progeny. Significantly higher residual DNA damage found after 15-min repair in preterm children compared to their mothers and higher residual DNA damage after 2 h compared to full-term newborns suggest a slower DNA repair capacity in preterm children. In comparison with preterm infants born by caesarean delivery, preterm infants born by vaginal delivery do repair more slowly the in vitro induced oxidative DNA damage. Final impact of passive smoking and of the slower DNA repair activity of preterm infants need to be confirmed in a larger study population combining transgenerational genetic and/or epigenetic effects, antioxidant levels, genotypes, repair enzyme efficiency/levels and infant morbidity.

Creep deformation, creep damage accumulation and residual life prediction for three low alloyed CrMo-steels

International Nuclear Information System (INIS)

Kondyr, A.; Sandstroem, R.; Samuelsson, A.

1979-02-01

A detailed analysis of creep strain results for three low alloyed steels of type 0.5 Mo, 1 Cr-0.5 Mo and 2.25 Cr-1 Mo has been undertaken. The results show that, excluding the primary stage, the true strain rate can be described by a simple analytical expression dE/dt = Aexp(B.E) where A and B are constants at constant stress and temperature. A is approximately equal to the minimum strain rate and B inversly proportional to the fracture strain. Furthermore, 1/AB equals the time t sub(r) to rupture. The residual life fraction in creep can be expressed as exp(-B.E) = 1-t/t sub(r) and a creep damage function μ is introduced as μ = 1-ABt. The expressions for strain rate and damage are shown to be a special case of the Rabotnov-Kachanov equations. The analysis has been generalized to account for multiaxial stress states, and as an example creep in a tube with internal pressure is considered. (author)

Grounding-Induced Sectional Forces and Residual Strength of Grounded Ship Hulls

DEFF Research Database (Denmark)

Paik, Jeom Kee; Pedersen, Preben Terndrup

1996-01-01

The aim of the present study is to determine the sectional forces induced by ship grounding and also to assess the residual strength of groundedship hulls. An analytical approach is used to estimate the grounding-induced sectional forces of ships. The extent and location of structural damage due...... to grounding is defined based on the ABS Safe Hull guide. The residual strength of damaged hulls is calculated by using a simple analytical formula. The method is applied to residual strength assessment of a damaged double hull tanker of 38,400 dwt due to grounding....

Residual-strength determination in polymetric materials

Energy Technology Data Exchange (ETDEWEB)

Christensen, R.M.

1981-10-01

Kinetic theory of crack growth is used to predict the residual strength of polymetric materials acted upon by a previous history. Specifically, the kinetic theory is used to characterize the state of growing damage that occurs under a constant-stress (load) state. The load is removed before failure under creep-rupture conditions, and the residual instantaneous strength is determined from the theory by taking account of the damage accumulation under the preceding constant-load history. The rate of change of residual strength is found to be strongest when the duration of the preceding load history is near the ultimate lifetime under that condition. Physical explanations for this effect are given, as are numerical examples. Also, the theoretical prediction is compared with experimental data.

Residual-strength determination in polymetric materials

International Nuclear Information System (INIS)

Christensen, R.M.

1981-01-01

Kinetic theory of crack growth is used to predict the residual strength of polymetric materials acted upon by a previous history. Specifically, the kinetic theory is used to characterize the state of growing damage that occurs under a constant-stress (load) state. The load is removed before failure under creep-rupture conditions, and the residual instantaneous strength is determined from the theory by taking account of the damage accumulation under the preceding constant-load history. The rate of change of residual strength is found to be strongest when the duration of the preceding load history is near the ultimate lifetime under that condition. Physical explanations for this effect are given, as are numerical examples. Also, the theoretical prediction is compared with experimental data

Cross-sections of spallation residues produced in 1A GeV 208Pb on proton reactions

International Nuclear Information System (INIS)

Wlazlo, W.; Uniwersytet Jagiellonski, Cracow; Enqvist, T.; Armbruster, P.

2000-02-01

Spallation residues produced in 1 GeV per nucleon 208 Pb on proton reactions have been studied using the fragment separator facility at GSI. Isotopic production cross-sections of elements from 61 Pm to 82 Pb have been measured down to 0.1 mb with a high accuracy. The recoil kinetic energies of the produced fragments were also determined. The obtained cross-sections agree with most of the few existing gamma-spectroscopy data. Data are compared with different intranuclear-cascade and evaporation-fission models. Drastic deviations were found for a standard code used in technical applications. (orig.)

Digital Imaging of Pipeline Mechanical Damage and Residual Stress

Science.gov (United States)

2010-02-19

The purpose of this program was to enhance characterization of mechanical damage in pipelines through application of digital eddy current imaging. Lift-off maps can be used to develop quantitative representations of mechanical damage and magnetic per...

Effects of fretting fatigue on the residual stress of shot peened Ti-6Al-4V samples

International Nuclear Information System (INIS)

Martinez, S.A.; Sathish, S.; Blodgett, M.P.; Mall, S.; Namjoshi, S.

2005-01-01

X-ray diffraction residual stress measurement has been utilized as nondestructive tool for the characterization of fretting fatigue damage in shot peened samples of Ti-6Al-4V. Prior to fretting fatigue damage, compressive residual stresses were found to be uniform over the entire face of the sample and independent of the measurement direction. After fretting fatigue, inside and in the vicinity of the fretting damage zone large relaxation of compressive residual stress was observed. An anisotropic residual stress distribution has been observed in the fretting fatigue damaged region. Residual stress measurements in interrupted fretting fatigue experiments showed that the relaxation of residual stress increases as the number of fretting fatigue cycles increase. The results are discussed in the light of their importance in establishing X-ray diffraction residual stress measurement technique as a nondestructive tool to characterize fretting fatigue damage

Measurement and interpretation of laser accelerated protons at GSI

International Nuclear Information System (INIS)

Al-Omari, Husam

2014-01-01

generated by the Matlab program, while the TraceWin code is employed to study the tracking through magnetic elements. - Chapter 6 describes the PHELIX laser parameters at GSI with chirp pulse amplification technique (CPA), and Gafchromic Radiochromic film (RCF) as a spatial energy resolver film detector. The results of experiments with laser proton acceleration, which were performed in two experimental areas at GSI (Z6 area and PHELIX Laser Hall (PLH)), are presented in section 6.3. - Chapter 7 includes the main results of this work, conclusions and gives a perspective for future experimental activities.

Measurement and interpretation of laser accelerated protons at GSI

Energy Technology Data Exchange (ETDEWEB)

Al-Omari, Husam

2014-04-28

generated by the Matlab program, while the TraceWin code is employed to study the tracking through magnetic elements. - Chapter 6 describes the PHELIX laser parameters at GSI with chirp pulse amplification technique (CPA), and Gafchromic Radiochromic film (RCF) as a spatial energy resolver film detector. The results of experiments with laser proton acceleration, which were performed in two experimental areas at GSI (Z6 area and PHELIX Laser Hall (PLH)), are presented in section 6.3. - Chapter 7 includes the main results of this work, conclusions and gives a perspective for future experimental activities.

Modeling of the fatigue damage accumulation processes in the material of NPP design units under thermomechanical unstationary effects. Estimation of spent life and forecast of residual life

International Nuclear Information System (INIS)

Kiriushin, A.I.; Korotkikh, Yu.G.; Gorodov, G.F.

2002-01-01

Full text: The estimation problems of spent life and forecast of residual life of NPP equipment design units, operated at unstationary thermal force loads are considered. These loads are, as a rule, unregular and cause rotation of main stress tensor platforms of the most loaded zones of structural elements and viscoelastic plastic deformation of material in the places of stresses concentrations. The existing engineering approaches to the damages accumulation processes calculation in the material of structural units, their advantages and disadvantages are analyzed. For the processes of fatigue damages accumulation a model is proposed, which allows to take into account the unregular pattern of deformation multiaxiality of stressed state, rotation of main platforms, non-linear summation of damages at the loading mode change. The model in based on the equations of damaged medium mechanics, including the equations of viscoplastic deformation of the material and evolutionary equations of damages accumulation. The algorithms of spent life estimation and residual life forecast of the controlled equipment and systems zones are made on the bases of the given model by the known real history of loading, which is determined by real model of NPP operation. The results of numerical experiments on the basis of given model for various processes of thermal force loads and their comparison with experimental results are presented. (author)

Rate-dependent performance of ion chambers for particle-ID at the GSI fragment separator

Energy Technology Data Exchange (ETDEWEB)

Hucka, Jan-Paul; Allred, Timothy; Enders, Joachim [Institut fuer Kernphysik, TU Darmstadt (Germany); Gernhaeuser, Roman; Maurus, Steffen [Physik Department, TU Muenchen (Germany); Nociforo, Chiara; Pietri, Stephane; Prochazka, Andrej [GSI Helmholtzzentrum fuer Schwerionenforschung (Germany)

2015-07-01

At the GSI Fragment Separator (FRS), multi-sampling ion chambers (MUSIC) employing a Frisch grid are used for charge identification of secondary ion beams. At the FAIR Super-FRS, higher rates are expected, and an event-by-event determination of the charge of secondary ions will be needed at rates of several 100000 events per second. The comparison of results from test measurements for the MUSIC performance with that of a recently constructed tilted-electrode gas ion chamber (TEGIC), which was designed similar to the one discussed, is presented.

Development of RF-linac and storage ring system for high-current experiments at GSI

International Nuclear Information System (INIS)

Hofmann, I.

1986-08-01

The heavy ion facility under construction at GSI is suitable for the generation of high-current beams. It consists of a new high-current injector into the Unilac and a synchrotron and storage ring. We discuss the capability of this system to produce short pulses of heavy ions with a specific energy of the order of 0.1 MJ/g. Under these conditions the system allows to perform a first generation of heavy ion driven target experiments and to test most of the critical issues of a large scale heavy ion fusion driver facility. (orig.)

{sup 96}Ru(p,{gamma}){sup 97}Rh measurement at the GSI storage ring

Energy Technology Data Exchange (ETDEWEB)

Zhong, Q; Aumann, T; Boretzky, K; Bosch, F; Braeuning, H; Brandau, C; Ershova, O; Geissel, H; Heil, M; Kelic, A; Kozhuharov, C; Langer, C; Bleis, T Le; Litvinov, Y A [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt, 64291 (Germany); Bishop, S; Dillmann, I [Technische Universitaet Muenchen, 85748 Garching (Germany); Blaum, K [Max-Planck-Institut fuer Kernphysik, 69117 Heidelberg (Germany); Davinson, T [University of Edinburgh, Edinburgh (United Kingdom); Gyuerky, G [Institute of Nuclear Research of the Hungarian Academy of Sciences (Hungary); Kaeppeler, F, E-mail: r.reifarth@gsi.d [Forschungszentrum Karlsruhe, Institut fuer Kernphysik, Karlsruhe (Germany)

2010-01-01

A pioneering experiment was recently performed at the Experimental Storage Ring (ESR) at GSI. Fully stripped ions of {sup 96}Ru were injected into the storage ring and slowed down to a few MeV per nucleon. The {sup 97}Rh ions from the {sup 96}Ru(p,{gamma}) reaction at a newly developed hydrogen jet target were detected with Double Sided Silicon Strip Detectors (DSSSD) mounted inside a pocket. The experiment and the status of the analysis at a beam energy of 11 MeV per nucleon will be presented.

Experience in determining the residual life expectancy of conventional thermal power stations

International Nuclear Information System (INIS)

Tolksdorf, E.

1990-01-01

A combination of computer analysis, degree of damage and approximate conversion to residual life expectancy gives acceptable results. There is considerable uncertainty in converting degree of damage to residual life expectancy, since structural component characteristics play a major role here. Structure damages play a major part in establishing the degree of damage. Damage categories are given, together with action if operations are to continue. Exhaustion calculations to TRD 508 are to be taken as conservative and as possible evidence of trends. 14 figs., 12 refs

Long-Term Strength of a Thick-Walled Pipe Filled with an Aggressive Medium, with Account for Damageability of the Pipe Material and Residual Strength

Science.gov (United States)

Piriev, S. A.

2018-01-01

This paper describes the study of scattered fracture of a thick-walled pipe filled with an aggressive medium, which creates uniform pressure on the inner surface of the pipe. It is assumed that the aggressive medium affects only the value of instantaneous strength. Damageability is described by an integral operator of the hereditary type. The problem is solved with allowance for residual strength of the pipe material behind the fracture front. Numerical calculation is carried out, and relationships between the fracture front coordinate and time for various concentrations of the aggressive medium and residual strength behind the fracture front are constructed.

Experiments on the interaction of heavy ions with dense plasma at GSI-Darmstadt

International Nuclear Information System (INIS)

Stoeckl, C.; Boine-Frankenheim, O.; Geissel, M.; Roth, M.; Wetzler, H.; Seelig, W.; Iwase, O.; Spiller, P.; Bock, R.; Suess, W.; Hoffmann, D.H.H.

1998-01-01

One of the main objectives of the experimental plasma physics activities at the Gesellschaft fuer Schwerionenforschung (GSI) are the interaction processes of heavy ions with dense ionized matter. Gas-discharge plasma targets were used for energy loss and charge state measurements in a regime of electron density and temperature up to 10 19 cm -3 and 20 eV, respectively. An improved model of the charge exchange processes in fully ionized hydrogen plasma, taking into account multiple excited electronic configurations which subsequently ionize, has removed the discrepancies of previous theoretical descriptions. The energy loss of the ion beam in partially ionized plasmas such as argon was found to agree very well with our simple theoretical model based on the modified Bethe-Bloch theory. A new setup with a 100 J/5 GW Nd-glass laser now provides access to density ranges up to 10 21 cm -3 and temperatures of up to 100 eV. First results of interaction experiments with laser-produced plasma are presented. To fully exploit the experimental possibilities of the new laser-plasma setup both improved charge state detection systems and better plasma diagnostics are indispensable. Present developments and future possibilities in these fields are presented. This paper summarizes the following contributions: Interaction of heavy-ion beams with laser plasma by C. Stoeckl et al. Energy loss of heavy ions in a laser-produced plasma by M. Roth et al. Charge state measurements of heavy ions passing a laser produced plasma with high time resolution by W. Suess et al. Plasma diagnostics for laser-produced plasma by O. Iwase et al. Future possibilities of plasma diagnostics at GSI by M. Geissel et al. (orig.)

Generic Safety Issue (GSI) 171 -- Engineered Safety Feature (ESF) failure from a loop subsequent to LOCA: Assessment of plant vulnerability and CDF contributions

International Nuclear Information System (INIS)

Martinez-Guridi, G.; Samanta, P.; Chu, L.; Yang, J.

1998-01-01

Generic Safety Issue 171 (GSI-171), Engineered Safety Feature (ESF) from a Loss Of Offsite Power (LOOP) subsequent to a Loss Of Coolant Accident (LOCA), deals with an accident sequence in which a LOCA is followed by a LOOP. This issue was later broadened to include a LOOP followed by a LOCA. Plants are designed to handle a simultaneous LOCA and LOOP. In this paper, the authors address the unique issues that are involved i LOCA with delayed LOOP (LOCA/LOOP) and LOOP with delayed LOCA (LOOP/LOCA) accident sequences. LOCA/LOOP accidents are analyzed further by developing event-tree/fault-tree models to quantify their contributions to core-damage frequency (CDF) in a pressurized water reactor and a boiling water reactor (PWR and a BWR). Engineering evaluation and judgments are used during quantification to estimate the unique conditions that arise in a LOCA/LOOP accident. The results show that the CDF contribution of such an accident can be a dominant contributor to plant risk, although BWRs are less vulnerable than PWRs

The symmetry energy at suprasaturation density and the ASY-EOS experiment at GSI

Directory of Open Access Journals (Sweden)

De Filippo E.

2017-01-01

Full Text Available The ASY-EOS experiment at GSI laboratory measured the direct and elliptic flow of neutrons and light charged particles in the reaction 197Au+197 Au at 400 A MeV incident energy. The ratio of elliptic flow of neutrons with respect to that of the light charged particles was used as main experimental observable to probe the density dependence of the symmetry energy term of the nuclear equation of state. Results, obtained by comparison of the experimental data with the UrQMD model predictions, strongly support a moderately soft to linear density dependence of the symmetry energy at suprasaturation densities below 2ρ0.

Analysis of the ways to decrease residual stresses on heat exchanging tubes and steam generator collector surfaces for reducing the material corrosion damage

International Nuclear Information System (INIS)

Stepanov, G.V.; Kharchenko, V.V.; Shatco, A.A.; Dranchenko, V.V.; Titov, V.F.

1994-01-01

Computer simulations have been carried out to analyze the effect of heat exchanger tube pressing forming process into a steam generator collector, on its residual stresses and strains. The program takes into consideration kinetic process peculiarities, material non-linear rheological properties, separate deformation of tubes and collectors in the presence of a clearance and their contact interaction, damage and crack appearance. 4 figs

Fatigue damage mechanics of notched graphite-epoxy laminates

Science.gov (United States)

Spearing, Mark; Beaumont, Peter W. R.; Ashby, Michael F.

A modeling approach is presented that recognizes that the residual properties of composite laminates after any form of loading depend on the damage state. Therefore, in the case of cyclic loading, it is necessary to first derive a damage growth law and then relate the residual properties to the accumulated damage. The propagation of fatigue damage in notched laminates is investigated. A power law relationship between damage growth and the strain energy release rate is developed. The material constants used in the model have been determined in independent experiments and are invariant for all the layups investigated. The strain energy release rates are calculated using a simple finite element representation of the damaged specimen. The model is used to predict the effect of tension-tension cyclic loading on laminates of the T300/914C carbon-fiber epoxy system. The extent of damage propagation is successfully predicted in a number of cross-ply laminates.

An estimation of core damage frequency of a pressurized water reactor during midloop operation due to loss of residual heat removal

International Nuclear Information System (INIS)

Chao, C.C.; Chen, C.T.; Lee, M.

1995-01-01

The core damage frequency caused by loss of residual heat removal (RHR) events was assessed during midloop operation of a Westinghouse-designed three-loop pressurized water reactor. The assessment considers two types of outages (refueling and drained maintenance) and uses failure data collected specifically for shutdown condition. Event trees were developed for five categories of loss of RHR events. Human actions to mitigate the loss of RHR events were identified and human error probabilities were quantified using the human cognitive reliability (HCR) and the technique for human error rate prediction (THERP) models. The results showed that the core damage frequency caused by loss of RHR events during midloop operation was 3.4 x 10 -5 per year. The results also showed that the core damage frequency can be reduced significantly by removing a pressurizer safety valve before entering midloop operation. The establishment of reflux cooling, i.e., decay heat removal through the steam generator secondary side, also plays an important role in mitigating the loss of RHR events during midloop operation

Analysis of the spallation residues and the associated particles in the reaction Fe+p at 1 GeV per nucleon; Analyse des residus de spallation et des particules associees dans la reaction Fe+p a 1 GeV par nucleon

Energy Technology Data Exchange (ETDEWEB)

Le Gentil, E

2006-09-15

SPALADIN is a new type of spallation experiment that has been carried out at the GSI accelerator facility (Germany) in order to improve the modelling of the spallation reaction. This experiment is based on the coincidence measurement in inverse kinematics of the spallation residues and the de-excitation fragments. This work presents the analysis of Fe{sup 56} + p reaction at 1 GeV per nucleon. Results on cross-sections and heavy residue velocity spectra are compared to previous data and enabled us to characterize the setup. Most of the element production cross-sections have been obtained with an uncertainty below 10 per cent. In the particular case of helium, its production cross-section has been measured to be {sigma}(1 GeV) = (598 {+-} 67) mb. The knowledge of this cross-section is important to assess the irradiation damage undergone by the window separating the accelerator from the target. The study of the de-excitation of the pre-fragment shows that the evaporation of light particles (Z {<=} 2) is the main way of de-excitation whatever the collision centrality. However, the de-excitation through the emission of intermediate mass fragments is observed in 5% of the events and most of these events correspond to a very asymmetric binary breaking. The velocity distributions of light residues (with regards to the mass of the projectile) show a significant disagreement with the average velocities predicted by spallation codes. (A.C.)

Atomic physics with highly-charged heavy ions at the GSI future facility: The scientific program of the SPARC collaboration

International Nuclear Information System (INIS)

Stoehlker, Th.; Beier, T.; Beyer, H.F.; Bosch, F.; Braeuning-Demian, A.; Gumberidze, A.; Hagmann, S.; Kozhuharov, C.; Kuehl, Th.; Liesen, D.; Mann, R.; Mokler, P.H.; Quint, W.; Schuch, R.; Warczak, A.

2005-01-01

In the current report a short overview about the envisioned program of the atomic physics research collaboration SPARC (Stored Particle Atomic Research Collaboration, at the new international accelerator Facility for Antiproton and Ion Research (FAIR) at GSI is given. In addition, a condensed description of the planned experimental areas devoted to atomic physics research at the new facility is presented

Outline of experimental schemes for measurements of thermophysical and transport properties in warm dense matter at GSI and FAIR

International Nuclear Information System (INIS)

Tauschwitz, Anna; Jacoby, Joachim; Maruhn, Joachim; Basko, Mikhail; Efremov, Vladimir; Iosilevskiy, Igor; Neumayer, Paul; Novikov, Vladimir; Tauschwitz, Andreas; Rosmej, Frank

2010-01-01

Different experimental schemes for investigation of warm dense matter produced with intense energetic ion beams are presented. The described target configurations allow direct measurements of thermophysical and transport properties of warm dense matter without hydrodynamic recalculations. The presented experiments will be realized at the current GSI synchrotron SIS-18 and the future FAIR facility in the framework of the WDM-collaboration.

Beam Diagnostics Challenges in the FAIR Project at GSI

International Nuclear Information System (INIS)

Peters, Andreas; Forck, Peter

2006-01-01

The planned FAIR (Facility for Antiproton and Ion Research) project consists of two heavy ion synchrotrons and four large storage rings, the existing GSI facility together with a new high-current proton linac will be used as the injector chain. The fast cycling, superconducting synchrotrons are build for high current operation with the aim of secondary ion and antiproton production. A large variety of low current secondary beams as well as the antiprotons are stored and cooled in the four storage rings. A complex operation scheme with multiple use of transport lines is foreseen. This demands an exceptional high dynamic range for the beam instrumentation. Due to the enormous beam power, non-destructive methods are mandatory for high currents as well as for the low current secondary beams due to the low repetition rate. Precise measurements of all beam parameters and automatic steering or feedback capabilities are required due to the necessary exploitation of the full ring acceptances. Moreover, online beam-corrections with short response times are mandatory for the fast ramping super-conducting magnets. An overview of the challenges and projected innovative solutions for various diagnostic installations will be given

Development of a GSI-Based, 2D-VAR Data Assimilation System for Operational Wave Guidance at the National Weather Service

Science.gov (United States)

Flampouris, S.; Alves, H.; Pondeca, M.

2016-02-01

The US National Centers for Environmental Prediction (NCEP) provides wave guidance to the National Weather Service (NWS) via a suite of operational wave models, which include three global-scale systems. An approach is being developed to include data assimilation into the global wave models using a 2D version of NCEP's grid-point statistical interpolation (2D-GSI), as described in Derber & Rosatti (1989), and Pondeca et al (2011). As a first step to the global implementation of a wave DA system, a prototype is being developed that will consist of adding wave heights as an analysis variable to the operational Real-Time Mesoscale Analysis (RTMA), which provides hourly analyses of several near sea-surface meteorological parameters, and supports a variety of applications within the NWS. The core of the RTMA is a 2D version of the GSI, which is a variational data assimilation system, and the first guess for the wave-height analysis is provided by NCEP's global wave models. For the new application, the RTMA will be modified to reflect background error covariances consistent with wave-height fields for regional and nearshore applications. In addition, quality control modules for in situ and altimeter significant wave height have been developed and integrated into the system. The strengths and the performance of the 2D-GSI are illustrated with both in situ and satellite measurements of significant wave height in the NW Atlantic and the Gulf of Mexico. The validation of follows the typical cross-validation procedure of RTMA products, based on 10% of the observations, for a period of 15 days. The error statistics (mean, root-mean-square) of the wave-height analysis shows significant improvement, relative to the first guess.

Challenges and opportunities for atomic physics at FAIR: The new GSI accelerator project

Energy Technology Data Exchange (ETDEWEB)

Hagmann, S. [Institut f. Kernphysik, University of Frankfurt (Germany) and GSI, Max Planckstr.1, Darmstadt (Germany)]. E-mail: s.hagmann@gsi.de; Beyer, H.F. [GSI, Max Planckstr.1, Darmstadt (Germany); Bosch, F. [GSI, Max Planckstr.1, Darmstadt (Germany); Braeuning-Demian, A. [GSI, Max Planckstr.1, Darmstadt (Germany); Kluge, H.-J. [GSI, Max Planckstr.1, Darmstadt (Germany); Kozhuharov, Ch. [GSI, Max Planckstr.1, Darmstadt (Germany); Kuehl, Th. [GSI, Max Planckstr.1, Darmstadt (Germany); Liesen, D. [GSI, Max Planckstr.1, Darmstadt (Germany); Stoehlker, Th. [GSI, Max Planckstr.1, Darmstadt (Germany); Ullrich, J. [Max Planck Inst. f. Kernphysik, Heidelberg (Germany); Moshammer, R. [Max Planck Inst. f. Kernphysik, Heidelberg (Germany); Mann, R. [GSI, Max Planckstr.1, Darmstadt (Germany); Mokler, P. [GSI, Max Planckstr.1, Darmstadt (Germany); Quint, W. [GSI, Max Planckstr.1, Darmstadt (Germany); Schuch, R. [Department of Physics, University of Stockholm (Sweden); Warczak, A. [Department of Physics, University of Cracow (Poland)

2005-12-15

We present a short overview of the current status of the new accelerator project FAIR at GSI with the new double synchrotron rings and the multi-storage rings. The key features of the new facility, which provides intense relativistic beams of stable and unstable nuclei, are introduced and their relation to the anticipated experimental programs in nuclear structure physics and antiproton physics is shown. The main emphasis in this overview is given to the atomic physics program with unique opportunities which will be provided e.g. by bare U{sup 92+} ions with kinetic energies continuously variable between relativistic energies corresponding to {gamma} up to {approx_equal}35 down to kinetic energies of such ions in traps corresponding to fractions of a Kelvin.

Energy dependence of isotopic spectra from spallation residues

International Nuclear Information System (INIS)

Audouin, L.

2003-09-01

Spallation reactions are collisions between heavy nuclei and light particle with an energy of a few hundreds MeV. The y are considered as a suitable way to create high- flux neutrons sources, which may used for example for the transmutation of nuclear wastes (hybrid reactors). The study of the residues from such reactions is both a way to understand the physics of the spallation and to provide information required for the design of industrial targets. The residues from the spallation of lead by proton at 500 MeV have been measured using the inverse kinematics technique in the FRS (fragments recoil separator). spectrometer from GSI (Barmstadt). This low energy required the use of new technique, for the experimental setup as well as during the analysis. The fragments were identified in-flight, prior to β decay. Complete isotopic distributions are obtained with an accuracy ranging between 10 and 30%. Detailed information on the reaction kinematics are also obtained. Data are in excellent agreement with radio-chemical measurements, and bring new insights about the spallation process. The comparison with data measured on the same system with an incident energy of 1 GeV allows to discuss the influence of the projectile energy on the residues formation. It is concluded that the independence of the shape of the isobaric production cross sections regarding mass and energy of the projectile is preserved at low incident energies. The behaviour of Monte-Carlo codes is discussed with respect to those sets of data. The calculations show an improving agreement with decreasing energy, indicating that high-energy phenomena, for which some common assumptions become questionable, are the main reason for the observed discrepancies. (author)

A Prototype Regional GSI-based EnKF-Variational Hybrid Data Assimilation System for the Rapid Refresh Forecasting System: Dual-Resolution Implementation and Testing Results

Science.gov (United States)

Pan, Yujie; Xue, Ming; Zhu, Kefeng; Wang, Mingjun

2018-05-01

A dual-resolution (DR) version of a regional ensemble Kalman filter (EnKF)-3D ensemble variational (3DEnVar) coupled hybrid data assimilation system is implemented as a prototype for the operational Rapid Refresh forecasting system. The DR 3DEnVar system combines a high-resolution (HR) deterministic background forecast with lower-resolution (LR) EnKF ensemble perturbations used for flow-dependent background error covariance to produce a HR analysis. The computational cost is substantially reduced by running the ensemble forecasts and EnKF analyses at LR. The DR 3DEnVar system is tested with 3-h cycles over a 9-day period using a 40/˜13-km grid spacing combination. The HR forecasts from the DR hybrid analyses are compared with forecasts launched from HR Gridpoint Statistical Interpolation (GSI) 3D variational (3DVar) analyses, and single LR hybrid analyses interpolated to the HR grid. With the DR 3DEnVar system, a 90% weight for the ensemble covariance yields the lowest forecast errors and the DR hybrid system clearly outperforms the HR GSI 3DVar. Humidity and wind forecasts are also better than those launched from interpolated LR hybrid analyses, but the temperature forecasts are slightly worse. The humidity forecasts are improved most. For precipitation forecasts, the DR 3DEnVar always outperforms HR GSI 3DVar. It also outperforms the LR 3DEnVar, except for the initial forecast period and lower thresholds.

A method to separate and quantify the effects of indentation size, residual stress and plastic damage when mapping properties using instrumented indentation

International Nuclear Information System (INIS)

Hou, X D; Jennett, N M

2017-01-01

Instrumented indentation is a convenient and increasingly rapid method of high resolution mapping of surface properties. There is, however, significant untapped potential for the quantification of these properties, which is only possible by solving a number of serious issues that affect the absolute values for mechanical properties obtained from small indentations. The three most pressing currently are the quantification of: the indentation size effect (ISE), residual stress, and pile-up and sink-in—which is itself affected by residual stress and ISE. Hardness based indentation mapping is unable to distinguish these effects. We describe a procedure that uses an elastic modulus as an internal reference and combines the information available from an indentation modulus map, a hardness map, and a determination of the ISE coefficient (using self-similar geometry indentation) to correct for the effects of stress, pile up and the indentation size effect, to leave a quantified map of plastic damage and grain refinement hardening in a surface. This procedure is used to map the residual stress in a cross-section of the machined surface of a previously stress free metal. The effect of surface grinding is compared to milling and is shown to cause different amounts of work hardening, increase in residual stress, and surface grain size reduction. The potential use of this procedure for mapping coatings in cross-section is discussed. (paper)

A method to separate and quantify the effects of indentation size, residual stress and plastic damage when mapping properties using instrumented indentation

Science.gov (United States)

Hou, X. D.; Jennett, N. M.

2017-11-01

Instrumented indentation is a convenient and increasingly rapid method of high resolution mapping of surface properties. There is, however, significant untapped potential for the quantification of these properties, which is only possible by solving a number of serious issues that affect the absolute values for mechanical properties obtained from small indentations. The three most pressing currently are the quantification of: the indentation size effect (ISE), residual stress, and pile-up and sink-in—which is itself affected by residual stress and ISE. Hardness based indentation mapping is unable to distinguish these effects. We describe a procedure that uses an elastic modulus as an internal reference and combines the information available from an indentation modulus map, a hardness map, and a determination of the ISE coefficient (using self-similar geometry indentation) to correct for the effects of stress, pile up and the indentation size effect, to leave a quantified map of plastic damage and grain refinement hardening in a surface. This procedure is used to map the residual stress in a cross-section of the machined surface of a previously stress free metal. The effect of surface grinding is compared to milling and is shown to cause different amounts of work hardening, increase in residual stress, and surface grain size reduction. The potential use of this procedure for mapping coatings in cross-section is discussed.

Residual capacity of a damaged water mist system

NARCIS (Netherlands)

Wal, R. van der; Rahm, M.; Hiltz, J.; Claesson, A.; Boonacker, B.

2013-01-01

Navies have been facing budget reductions over the past decade. Since crew size is a major cost driver, this has led to efforts to reduce manning on board naval ships. Traditionally, damage control and firefighting were manpower intensive operations. To enable crewing level reductions without

Biology experiments at UNILAC. Reports from the biology user meeting, GSI, 3 October 1985

International Nuclear Information System (INIS)

1985-10-01

On 3 Oct 1985, an internal Biology User Meeting of the groups working at GSI was arranged for the purpose of exchanging information and having discussions. It was found that the experimental data obtained so far are quite complex, and that the attempts at a theoretical treatment are still in a very early stage. To keep the discussion going, this report therefore presents the contributions of the various groups as far as these have been available. Most of the information was not in finished reports but in the form of diagrams and tables with explanations, sometimes even in the form of handwritten notes or sketches. Separate records are available for 13 contributions. (orig./MG) [de

Selective logging and damage to unharvested trees in a hyrcanian forest of Iran

OpenAIRE

Farshad Keivan Behjou; Omid Ghafarzade Mollabashi

2012-01-01

Selective logging in mature hardwood stands of Caspian forests often causes physical damage to residual trees through felling and skidding operations, resulting in a decline in bole quality and subsequent loss of tree value. This study evaluated the logging damage to residual trees following logging operations. A total density of 5.1 trees/ha and 17.3 m3/ha of wood were harvested. On average, 9.8 trees were damaged for every tree extracted, including 8 trees destroyed or severely damaged. The...

The optimized advanced demonstrator for the SC CW heavy ion linac at GSI

Energy Technology Data Exchange (ETDEWEB)

Schwarz, Malte; Basten, Markus; Busch, Marco; Dziuba, Florian; Podlech, Holger; Ratzinger, Ulrich; Tiede, Rudolf [Institut fuer Angewandte Physik, Goethe-Universitaet Frankfurt am Main (Germany); Gettmann, Viktor; Heilmann, Manuel [GSI Helmholtzzentrum, Darmstadt (Germany); Barth, Winfried; Mickat, Sascha [GSI Helmholtzzentrum, Darmstadt (Germany); HIM, Helmholtzinstitut, Mainz (Germany); Miski-Oglu, Maksym [HIM, Helmholtzinstitut, Mainz (Germany); Aulenbacher, Kurt [KPH, Johannes Gutenberg Universitaet, Mainz (Germany)

2016-07-01

For future experiments with heavy ions at the coulomb barrier within the SHE research project a multi-stage R and D program of GSI, HIM and IAP is currently under progress. It aims at developing a superconducting (sc) continuous wave (cw) LINAC with multiple CH-cavities as key components. As intermediate step towards the whole LINAC, the Optimized Advanced Demonstrator is proposed. Consisting of short CH-cavities and cryostats, it could provide several advantages regarding velocity acceptance, higher tolerance with respect to frequency and field deviation, easier mounting, handling and maintenance as well as a more robust longitudinal beam dynamic. The beam dynamics concept is based on EQUUS (Equidistant Multigap Structure) constant-beta cavities. The corresponding simulations for the proposed next extension stage - the Optimized Advanced Demonstrator - will be presented.

Sharing Residual Liability

DEFF Research Database (Denmark)

Carbonara, Emanuela; Guerra, Alice; Parisi, Francesco

2016-01-01

Economic models of tort law evaluate the efficiency of liability rules in terms of care and activity levels. A liability regime is optimal when it creates incentives to maximize the value of risky activities net of accident and precaution costs. The allocation of primary and residual liability...... for policy makers and courts in awarding damages in a large number of real-world accident cases....

A Large-scale Finite Element Model on Micromechanical Damage and Failure of Carbon Fiber/Epoxy Composites Including Thermal Residual Stress

Science.gov (United States)

Liu, P. F.; Li, X. K.

2018-06-01

The purpose of this paper is to study micromechanical progressive failure properties of carbon fiber/epoxy composites with thermal residual stress by finite element analysis (FEA). Composite microstructures with hexagonal fiber distribution are used for the representative volume element (RVE), where an initial fiber breakage is assumed. Fiber breakage with random fiber strength is predicted using Monte Carlo simulation, progressive matrix damage is predicted by proposing a continuum damage mechanics model and interface failure is simulated using Xu and Needleman's cohesive model. Temperature dependent thermal expansion coefficients for epoxy matrix are used. FEA by developing numerical codes using ANSYS finite element software is divided into two steps: 1. Thermal residual stresses due to mismatch between fiber and matrix are calculated; 2. Longitudinal tensile load is further exerted on the RVE to perform progressive failure analysis of carbon fiber/epoxy composites. Numerical convergence is solved by introducing the viscous damping effect properly. The extended Mori-Tanaka method that considers interface debonding is used to get homogenized mechanical responses of composites. Three main results by FEA are obtained: 1. the real-time matrix cracking, fiber breakage and interface debonding with increasing tensile strain is simulated. 2. the stress concentration coefficients on neighbouring fibers near the initial broken fiber and the axial fiber stress distribution along the broken fiber are predicted, compared with the results using the global and local load-sharing models based on the shear-lag theory. 3. the tensile strength of composite by FEA is compared with those by the shear-lag theory and experiments. Finally, the tensile stress-strain curve of composites by FEA is applied to the progressive failure analysis of composite pressure vessel.

Residual Strength of In-plane Loaded Debonded Sandwich Panels

DEFF Research Database (Denmark)

Berggreen, Carl Christian; Simonsen, Bo Cerup

2005-01-01

This paper presents a FEM based numerical model for prediction of residual strength of damaged sandwich panels. As demonstrated, the model can predict the maximum load carrying capacity of real-life panels with debond damages, where the failure is governed by face-sheet buckling followed by debond...

Residual stresses caused by head-on and 45° foreign object damage for a laser shock peened Ti–6Al–4V alloy aerofoil

International Nuclear Information System (INIS)

Zabeen, S.; Preuss, M.; Withers, P.J.

2013-01-01

This paper investigates the effect on the residual stresses of foreign object damage (FOD) to a previously laser shock peened (LSP) leading edge (LE). FOD was introduced onto the LE of the aerofoil-shaped specimen through ballistic impacts of a cube edge at angles of 0° and 45° to the leading edge. The residual stress distribution was mapped around the FOD notch by synchrotron X-ray diffraction. The results suggest that for both impact angles, the FOD event superimposed a significant additional residual stress on top of the pre-existing stress associated with the LSP process. In particular, the compressive stress was found to be largest directly beneath the notch and the tensile region, seen previously for unpeened aerofoils beneath the compressive zone, was absent due to the pre-existing peening stress field. This may help to explain the improved fatigue strength observed previously. It is shown that the FOD notch created by 45° impact was asymmetric in shape and smaller in depth compared to that created at 0°. The residual stresses were somewhat larger for the 0° impact condition than for 45° partly due to the larger notch depth introduced in the former case.

Construction and building of a compact RFQ spiral structure for the stopping of highly charged heavy ion beams for the HITRAP project of the GSI; Konstruktion und Aufbau einer kompakten RFQ-Spiral-Struktur zum Abbremsen hochgeladener Schwerionenstrahlen fuer das HITRAP-Projekt der GSI

Energy Technology Data Exchange (ETDEWEB)

Hofmann, B.

2007-07-01

For experiments of the atomic-physics group of the GSI in Darmstadt an ion stopper is built, which will make low-energetic, extremely highly charged ions available. The plannings for the so-called HITRAP (highly charged ion's trap) began at the beginning of the ninetieth. With this facility highly-charged heavy ions shall be stopped in two stages to very low, thermal velocities, and be available for highly precise mass spectroscopy, measurements of the g factor of the bound electron of hydrogen-like ions, and other atomic-physics experiments. This decelerator facility shall first be built in the reinjection channel behind the ESR with the possibility, to apply all components later in teh extension of the GSI in the framework of the FAIR project in the facility for low-energetic antiprotons and ions to be newly built. the present thesis treats the development and the building of an integrated RFQ debuncher stopping accelerator, which represents a part of the HITRAP stopping structures. By this the ion beam is stopped from the IH stopping accelerator with an energy of 500 keV/u to 5 keV/u. By the integrated spiral buncher the beam can be fitted in energy and energy deviation to the subsequent cooler trap. In this thesis the foundations of the particle dynamics in a RFQ accelerator for the stopping of particle beams were worked out and realized, the particle-dynamics calculations necessary for the lay-out of such a structure performed with RFQSim, suitable RF structures with the simulation program Microwave Studio developed and studied, as well as the thermal load of the structures studied with the finite-element code ALGOR. A further, central topic of this thesis is the building and the tuning of the RFQ structure in order to reach a homogeneous as possible field distribution along the electrodes. Measurements of the fields in the RFQ were performed with a disturbing condenser, at the debuncher with a disturbing body. After successfully performed vacuum tests at

Studies on fission with ALADIN. Precise and simultaneous measurement of fission yields, total kinetic energy and total prompt neutron multiplicity at GSI

International Nuclear Information System (INIS)

Martin, Julie-Fiona; Taieb, Julien; Chatillon, Audrey; Belier, Gilbert; Boutoux, Guillaume; Ebran, Adeline; Gorbinet, Thomas; Grente, Lucie; Laurent, Benoit; Pellereau, Eric; Alvarez-Pol, Hector; Ayyad, Yassid; Benlliure, Jose; Cortina Gil, Dolores; Caamano, Manuel; Fernandez Dominguez, Beatriz; Paradela, Carlos; Ramos, Diego; Rodriguez-Sanchez, Jose-Luis; Vargas, Jossitt; Audouin, Laurent; Tassan-Got, Laurent; Aumann, Thomas; Casarejos, Enrique; Farget, Fanny; Rodriguez-Tajes, Carme; Heinz, Andreas; Jurado, Beatriz; Kelic-Heil, Aleksandra; Kurz, Nikolaus; Nociforo, Chiara; Pietri, Stephane; Rossi, Dominic; Schmidt, Karl-Heinz; Simon, Haik; Voss, Bernd; Weick, Helmut

2015-01-01

A novel technique for fission studies, based on the inverse kinematics approach, is presented. Following pioneering work in the nineties, the SOFIA Collaboration has designed and built an experimental set-up dedicated to the simultaneous measurement of isotopic yields, total kinetic energies and total prompt neutron multiplicities, by fully identifying both fission fragments in coincidence, for the very first time. This experiment, performed at GSI, permits to study the fission of a wide variety of fissioning systems, ranging from mercury to neptunium, possibly far from the valley of stability. A first experiment, performed in 2012, has provided a large array of unprecedented data regarding the nuclear fission process. An excerpt of the results is presented. With this solid starter, further improvements of the experimental set-up are considered, which are consistent with the expected developments at the GSI facility, in order to measure more fission observables in coincidence. The completeness reached in the SOFIA data, permits to scrutinize the correlations between the interesting features of fission, offering a very detailed insight in this still unraveled mechanism. (orig.)

Studies on fission with ALADIN. Precise and simultaneous measurement of fission yields, total kinetic energy and total prompt neutron multiplicity at GSI

Energy Technology Data Exchange (ETDEWEB)

Martin, Julie-Fiona; Taieb, Julien; Chatillon, Audrey; Belier, Gilbert; Boutoux, Guillaume; Ebran, Adeline; Gorbinet, Thomas; Grente, Lucie; Laurent, Benoit; Pellereau, Eric [CEA DAM Bruyeres-le-Chatel, Arpajon (France); Alvarez-Pol, Hector; Ayyad, Yassid; Benlliure, Jose; Cortina Gil, Dolores; Caamano, Manuel; Fernandez Dominguez, Beatriz; Paradela, Carlos; Ramos, Diego; Rodriguez-Sanchez, Jose-Luis; Vargas, Jossitt [Universidad de Santiago de Compostela, Santiago de Compostela (Spain); Audouin, Laurent; Tassan-Got, Laurent [CNRS/IN2P3, IPNO, Orsay (France); Aumann, Thomas [Technische Universitaet Darmstadt, Darmstadt (Germany); Casarejos, Enrique [Universidad de Vigo, Vigo (Spain); Farget, Fanny; Rodriguez-Tajes, Carme [CNRS/IN2P3, GANIL, Caen (France); Heinz, Andreas [Chalmers University of Technology, Gothenburg (Sweden); Jurado, Beatriz [CNRS/IN2P3, CENBG, Gradignan (France); Kelic-Heil, Aleksandra; Kurz, Nikolaus; Nociforo, Chiara; Pietri, Stephane; Rossi, Dominic; Schmidt, Karl-Heinz; Simon, Haik; Voss, Bernd; Weick, Helmut [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany)

2015-12-15

A novel technique for fission studies, based on the inverse kinematics approach, is presented. Following pioneering work in the nineties, the SOFIA Collaboration has designed and built an experimental set-up dedicated to the simultaneous measurement of isotopic yields, total kinetic energies and total prompt neutron multiplicities, by fully identifying both fission fragments in coincidence, for the very first time. This experiment, performed at GSI, permits to study the fission of a wide variety of fissioning systems, ranging from mercury to neptunium, possibly far from the valley of stability. A first experiment, performed in 2012, has provided a large array of unprecedented data regarding the nuclear fission process. An excerpt of the results is presented. With this solid starter, further improvements of the experimental set-up are considered, which are consistent with the expected developments at the GSI facility, in order to measure more fission observables in coincidence. The completeness reached in the SOFIA data, permits to scrutinize the correlations between the interesting features of fission, offering a very detailed insight in this still unraveled mechanism. (orig.)

Lysine residue 185 of Rad1 is a topological but not a functional counterpart of lysine residue 164 of PCNA.

Directory of Open Access Journals (Sweden)

Niek Wit

Full Text Available Monoubiquitylation of the homotrimeric DNA sliding clamp PCNA at lysine residue 164 (PCNA(K164 is a highly conserved, DNA damage-inducible process that is mediated by the E2/E3 complex Rad6/Rad18. This ubiquitylation event recruits translesion synthesis (TLS polymerases capable of replicating across damaged DNA templates. Besides PCNA, the Rad6/Rad18 complex was recently shown in yeast to ubiquitylate also 9-1-1, a heterotrimeric DNA sliding clamp composed of Rad9, Rad1, and Hus1 in a DNA damage-inducible manner. Based on the highly similar crystal structures of PCNA and 9-1-1, K185 of Rad1 (Rad1(K185 was identified as the only topological equivalent of PCNA(K164. To investigate a potential role of posttranslational modifications of Rad1(K185 in DNA damage management, we here generated a mouse model with a conditional deletable Rad1(K185R allele. The Rad1(K185 residue was found to be dispensable for Chk1 activation, DNA damage survival, and class switch recombination of immunoglobulin genes as well as recruitment of TLS polymerases during somatic hypermutation of immunoglobulin genes. Our data indicate that Rad1(K185 is not a functional counterpart of PCNA(K164.

Radiation-induced DNA damage in tumors and normal tissues. II. Influence of dose, residual DNA damage and physiological factors in oxygenated cells

International Nuclear Information System (INIS)

Zhang, H.; Wheeler, K.T.

1994-01-01

Detection and quantification of hypoxic cells in solid tumors is important for many experimental and clinical situations. Several laboratories, including ours, have suggested that assays which measure radiation-induced DNA strand breaks and DNA-protein crosslinks (DPCs) might be used to detect or quantify hypoxic cells in tumors and normal tissues. Recently, we demonstrated the feasibility of using an alkaline elution assay that measures strand breaks and DPCs to detect and/or quantify hypoxic cells in tissues. For this approach to be valid, DPCs must not be formed to any great extent in irradiated oxygenated cells, and the formation and repair of strand breaks and DPCs in oxygenated cells must not be modified appreciably by physiological factors (e.g., temperature, pH and nutrient depletion) that are often found in solid tumors. To address these issues, two sets of experiments were performed. In one set of experiments, oxygenated 9L cells in tissue culture, subcutaneous 9L tumors and rat cerebella were irradiated with doses of 15 or 50 Gy and allowed to repair until the residual strand break damage was low enough to detect DPCs. In another set of experiments, oxygenated exponentially growing or plateau-phase 9L cells in tissue culture were irradiated with a dose of 15 Gy at 37 or 20 degrees C, while the cells were maintained at a pH of either 6.6 or 7.3. DNA-protein crosslinks were formed in oxygenated cells about 100 times less efficiently than in hypoxic cells. In addition, temperature, pH, nutrient depletion and growth phase did not appreciably alter the formation and repair of strand breaks or the formation of DPCs in oxygenated 9L cells. These results support the use of this DNA damage assay for the detection and quantification of hypoxic cells in solid tumors. 27 refs., 5 tabs

Tune measurements with high intensity ion beams at GSI SIS-18

Energy Technology Data Exchange (ETDEWEB)

Singh, Rahul [GSI, Darmstadt (Germany); TEMF, TU Darmstadt (Germany); Forck, Peter; Kowina, Piotr; Kaufmann, Wolfgang [GSI, Darmstadt (Germany); Weiland, Thomas [TEMF, TU Darmstadt (Germany)

2012-07-01

A precise tune measurement during a full accelerating cycle is required to achieve stable high current operation. A new system has been commissioned at GSI for position, orbit and tune measurements. It consists of three distinct parts; an exciter which provides power to excite coherent betatron oscillations in the bunched beam; Fast ADCs to digitize the BPM signals at 125 MSa/s; the post processing electronics uses digitized BPM signals to acquire one position value per bunch. Subsequently the baseband tune is determined by Fourier transformation of the position data. Experiments were conducted to understand the effects of high beam intensity on tune at injection plateau (11.4 MeV/u) and during acceleration ramp (11.4-600 MeV/u). These experiments were performed with U{sup 73+} and Ar{sup 18+} ion beam at highest achievable intensities of 2.10{sup 9} and 2.5.10{sup 10} respectively. Tune shift with increased intensity was observed. The working principle of the tune measurement system and observed high intensity effects on tune will be reported in this contribution.

Analysis of factors influencing fire damage to concrete using nonlinear resonance vibration method

Energy Technology Data Exchange (ETDEWEB)

Park, Gang Kyu; Park, Sun Jong; Kwak, Hyo Gyoung [Civil and Environmental Engineering, Korea Advanced Institute of Science and Technology, KAIST, Daejeon (Korea, Republic of); Yim, Hong Jae [Dept. of Construction and Disaster Prevention Engineering, Kyungpook National University, Sangju (Korea, Republic of)

2015-04-15

In this study, the effects of different mix proportions and fire scenarios (exposure temperatures and post-fire-curing periods) on fire-damaged concrete were analyzed using a nonlinear resonance vibration method based on nonlinear acoustics. The hysteretic nonlinearity parameter was obtained, which can sensitively reflect the damage level of fire-damaged concrete. In addition, a splitting tensile strength test was performed on each fire-damaged specimen to evaluate the residual property. Using the results, a prediction model for estimating the residual strength of fire-damaged concrete was proposed on the basis of the correlation between the hysteretic nonlinearity parameter and the ratio of splitting tensile strength.

Feasibility Study of Using Gemstone Spectral Imaging (GSI) and Adaptive Statistical Iterative Reconstruction (ASIR) for Reducing Radiation and Iodine Contrast Dose in Abdominal CT Patients with High BMI Values.

Science.gov (United States)

Zhu, Zheng; Zhao, Xin-ming; Zhao, Yan-feng; Wang, Xiao-yi; Zhou, Chun-wu

2015-01-01

To prospectively investigate the effect of using Gemstone Spectral Imaging (GSI) and adaptive statistical iterative reconstruction (ASIR) for reducing radiation and iodine contrast dose in abdominal CT patients with high BMI values. 26 patients (weight > 65kg and BMI ≥ 22) underwent abdominal CT using GSI mode with 300mgI/kg contrast material as study group (group A). Another 21 patients (weight ≤ 65kg and BMI ≥ 22) were scanned with a conventional 120 kVp tube voltage for noise index (NI) of 11 with 450mgI/kg contrast material as control group (group B). GSI images were reconstructed at 60keV with 50%ASIR and the conventional 120kVp images were reconstructed with FBP reconstruction. The CT values, standard deviation (SD), signal-noise-ratio (SNR), contrast-noise-ratio (CNR) of 26 landmarks were quantitatively measured and image quality qualitatively assessed using statistical analysis. As for the quantitative analysis, the difference of CNR between groups A and B was all significant except for the mesenteric vein. The SNR in group A was higher than B except the mesenteric artery and splenic artery. As for the qualitative analysis, all images had diagnostic quality and the agreement for image quality assessment between the reviewers was substantial (kappa = 0.684). CT dose index (CTDI) values for non-enhanced, arterial phase and portal phase in group A were decreased by 49.04%, 40.51% and 40.54% compared with group B (P = 0.000), respectively. The total dose and the injection rate for the contrast material were reduced by 14.40% and 14.95% in A compared with B. The use of GSI and ASIR provides similar enhancement in vessels and image quality with reduced radiation dose and contrast dose, compared with the use of conventional scan protocol.

Feasibility Study of Using Gemstone Spectral Imaging (GSI and Adaptive Statistical Iterative Reconstruction (ASIR for Reducing Radiation and Iodine Contrast Dose in Abdominal CT Patients with High BMI Values.

Directory of Open Access Journals (Sweden)

Zheng Zhu

Full Text Available To prospectively investigate the effect of using Gemstone Spectral Imaging (GSI and adaptive statistical iterative reconstruction (ASIR for reducing radiation and iodine contrast dose in abdominal CT patients with high BMI values.26 patients (weight > 65kg and BMI ≥ 22 underwent abdominal CT using GSI mode with 300mgI/kg contrast material as study group (group A. Another 21 patients (weight ≤ 65kg and BMI ≥ 22 were scanned with a conventional 120 kVp tube voltage for noise index (NI of 11 with 450mgI/kg contrast material as control group (group B. GSI images were reconstructed at 60keV with 50%ASIR and the conventional 120kVp images were reconstructed with FBP reconstruction. The CT values, standard deviation (SD, signal-noise-ratio (SNR, contrast-noise-ratio (CNR of 26 landmarks were quantitatively measured and image quality qualitatively assessed using statistical analysis.As for the quantitative analysis, the difference of CNR between groups A and B was all significant except for the mesenteric vein. The SNR in group A was higher than B except the mesenteric artery and splenic artery. As for the qualitative analysis, all images had diagnostic quality and the agreement for image quality assessment between the reviewers was substantial (kappa = 0.684. CT dose index (CTDI values for non-enhanced, arterial phase and portal phase in group A were decreased by 49.04%, 40.51% and 40.54% compared with group B (P = 0.000, respectively. The total dose and the injection rate for the contrast material were reduced by 14.40% and 14.95% in A compared with B.The use of GSI and ASIR provides similar enhancement in vessels and image quality with reduced radiation dose and contrast dose, compared with the use of conventional scan protocol.

X-ray diffraction study of microstructural changes during fatigue damage initiation in steel pipes

Energy Technology Data Exchange (ETDEWEB)

Pinheiro, B., E-mail: bianca@lts.coppe.ufrj.br [Laboratory of Mechanics of Lille (LML), UMR CNRS 8107, University of Lille 1, Boulevard Paul Langevin, Cite Scientifique, 59655 Villeneuve d' Ascq (France); Lesage, J. [Laboratory of Mechanics of Lille (LML), UMR CNRS 8107, University of Lille 1, Boulevard Paul Langevin, Cite Scientifique, 59655 Villeneuve d' Ascq (France); Pasqualino, I. [Subsea Technology Laboratory (LTS), Ocean Engineering Department, COPPE/Federal University of Rio de Janeiro, PO Box 68508, Cidade Universitaria, CEP 21945-970, Rio de Janeiro/RJ (Brazil); Benseddiq, N. [Laboratory of Mechanics of Lille (LML), UMR CNRS 8107, University of Lille 1, Boulevard Paul Langevin, Cite Scientifique, 59655 Villeneuve d' Ascq (France); Bemporad, E. [Interdepartmental Laboratory of Electron Microscopy (LIME), University of Rome TRE, Via Della Vasca Navale 79, 00146 Rome (Italy)

2012-01-15

Highlights: Black-Right-Pointing-Pointer In this work we study the fatigue damage evolution in an API 5L X60 steel. Black-Right-Pointing-Pointer Microstructural changes and residual stresses are evaluated during fatigue tests. Black-Right-Pointing-Pointer Microdeformations and macro residual stresses are estimated by X-ray diffraction. Black-Right-Pointing-Pointer Results are discussed in view of an indicator of fatigue damage initiation. Black-Right-Pointing-Pointer This indicator could allow the prediction of residual life before macrocracking. - Abstract: Steel pipes used in the oil and gas industry undergo the action of cyclic loads that can cause their failure by fatigue. A consistent evaluation of the fatigue damage during the initiation phase should fundamentally be based on a nanoscale approach, i.e., at the scale of the dislocation network, in order to take into account the micromechanisms of fatigue damage that precede macrocrack initiation and propagation until the final fracture. In this work, microstructural changes related to fatigue damage initiation are investigated in the API 5L X60 grade steel, used in pipe manufacturing. Microdeformations and macro residual stress are evaluated using X-ray diffraction in real time during alternating bending fatigue tests performed on samples cut off from an X60 steel pipe. The aim of this ongoing work is to provide ground for further development of an indicator of fatigue damage initiation in X60 steel. This damage indicator could allow a good residual life prediction of steel pipes previously submitted to fatigue loading, before macroscopic cracking, and help to increase the reliability of these structures.

Experiment and numerical simulation of welding induced damage: stainless steel 15-5PH

International Nuclear Information System (INIS)

Wu, T.

2007-11-01

The objective of this study is the prediction of damage and residual stresses induced by hot processing which leads to phase transformation in martensitic stainless steel. This study firstly concerns the modelling of the damage of material induced by a complex history of thermo-elastoplastic multiphase in heat-affected-zone (HAZ) of welding. In this work, a two-scale mode of elastoplastic damage multiphase was developed in the framework of thermodynamics of irreversible process. The constitutive equations are coupling with ductile damage, elasto-plasticity, phase transformation, and transformation plasticity. Besides, a damage equation was proposed based on the Lemaitre's damage model in the framework of continuum damage mechanics. The experiments of 15-5PH were implemented for the identification of phase transformation, transformation plasticity and damage models. Tensile tests of round specimens were used to identify the parameters of damage model as well as mechanical behaviours at various temperatures. Tests of flat notched specimen were designed to provide the validation of damage model and strain localization using three dimensional image correlation technologies. In addition, microscopic analysis was performed to provide microstructure characterization of 15-5PH and to discover the damage mechanism. Finally the numerical simulation was performed in the code CAST3M of CEA. On the one hand, numerical verification of the flat notched plates was implemented and compared with experimental results. On the other hand, we used the two-scale model including phase transformation, transformation plasticity and damage to simulate the level of residual stresses of a disk made of 15-5PH metal heated by laser. The internal variables, such as strain, stress, damage, were successfully traced in the simulation of two-scale model. The simulation results showed the transformation plasticity changes the level of residual stresses and should not be negligible; damage decreases

Residual haematopoietic damage in adult and 8 day-old mice exposed to 7 Gy of x-rays

International Nuclear Information System (INIS)

Grande, T.; Bueren, J.A.; Gaitan, S.; Tejero, C.

1993-01-01

The authors' experiments have focused on the analysis of residual haematopoietic damage in 8-day-old and 12-week-old mice X-irradiated with a single dose of 7 Gy. In the case of adult mice, analysis of femoral and splenic CFU-S, CFU-GM and BFU-E showed a persistent depletion of these haematopoietic progenitor cells after irradiation. In contrast, in 1-week-old irradiated mice, a progressive recovery of the femoral haematopoietic progenitors was observed, achieving essentially normal values 1 year after irradiation. The spleens of these mice, however, contained significantly less haematopoietic progenitors than the control group, mainly as a consequence of the size reduction of this organ. In the peripheral blood, normal cellularity values were observed in most cases, although in the adult group a decline in numbers or circulating cells was noted after the first year following irradiation. (author)

Distortion and residual stresses in structures reinforced with titanium straps for improved damage tolerance

International Nuclear Information System (INIS)

Liljedahl, C.D.M.; Fitzpatrick, M.E.; Edwards, L.

2008-01-01

Distortion and residual stresses induced during the manufacturing process of bonded crack retarders have been investigated. Titanium alloy straps were adhesively bonded to an aluminium alloy SENT specimen to promote fatigue crack growth retardation. The effect of three different strap dimensions was investigated. The spring-back of a component when released from the autoclave and the residual stresses are important factors to take into account when designing a selective reinforcement, as this may alter the local aerodynamic characteristics and reduce the crack bridging effect of the strap. The principal problem with residual stresses is that the tensile nature of the residual stresses in the primary aluminium structure has a negative impact on the crack initiation and crack propagation behaviour in the aluminium. The residual stresses were measured with neutron diffraction and the distortion of the specimens was measured with a contour measurement machine. The bonding process was simulated with a three-dimensional FE model. The residual stresses were found to be tensile close to the strap and slightly compressive on the un-bonded side. Both the distortion and the residual stresses increased with the thickness and the width of the strap. Very good agreement between the measured stresses and the measured distortion and the FE simulation was found

Quantification of Residual Stress from Photonic Signatures of Fused Silica

Science.gov (United States)

Cramer, K. Elliott; Hayward, Maurice; Yost, William E.

2013-01-01

A commercially available grey-field polariscope (GFP) instrument for photoelastic examination is used to assess impact damage inflicted upon the outer-most pane of Space Shuttle windows made from fused silica. A method and apparatus for calibration of the stress-optic coefficient using four-point bending is discussed. The results are validated on known material (acrylic) and are found to agree with literature values to within 6%. The calibration procedure is then applied to fused-silica specimens and the stress-optic coefficient is determined to be 2.43 +/- 0.54 x 10(exp -12)/Pa. Fused silica specimens containing impacts artificially made at NASA's Hypervelocity Impact Technology Facility (HIT-F), to simulate damage typical during space flight, are examined. The damage sites are cored from fused silica window carcasses and examined with the GFP. The calibrated GFP measurements of residual stress patterns surrounding the damage sites are presented. Keywords: Glass, fused silica, photoelasticity, residual stress

Alleviating inequality in climate policy costs: an integrated perspective on mitigation, damage and adaptation

Science.gov (United States)

De Cian, E.; Hof, A. F.; Marangoni, G.; Tavoni, M.; van Vuuren, D. P.

2016-07-01

Equity considerations play an important role in international climate negotiations. While policy analysis has often focused on equity as it relates to mitigation costs, there are large regional differences in adaptation costs and the level of residual damage. This paper illustrates the relevance of including adaptation and residual damage in equity considerations by determining how the allocation of emission allowances would change to counteract regional differences in total climate costs, defined as the costs of mitigation, adaptation, and residual damage. We compare emission levels resulting from a global carbon tax with two allocations of emission allowances under a global cap-and-trade system: one equating mitigation costs and one equating total climate costs as share of GDP. To account for uncertainties in both mitigation and adaptation, we use a model-comparison approach employing two alternative modeling frameworks with different damage, adaptation cost, and mitigation cost estimates, and look at two different climate goals. Despite the identified model uncertainties, we derive unambiguous results on the change in emission allowance allocation that could lessen the unequal distribution of adaptation costs and residual damages through the financial transfers associated with emission trading.

A beamline for x-ray laser spectroscopy at the experimental storage ring at GSI

International Nuclear Information System (INIS)

Winters, D F A; Bagnoud, V; Ecker, B; Eisenbarth, U; Götte, S; Kuehl, Th; Stöhlker, Th; Zielbauer, B; Neumayer, P; Spielmann, C

2013-01-01

By combining an x-ray laser (XRL) with a heavy-ion storage ring, precision laser spectroscopy of the fine-structure splitting in heavy Li-like ions will be possible. An initial study has been performed to determine the feasibility of a first experiment at the experimental storage ring at GSI in Darmstadt, which also has great potential for the experiments planned for FAIR. We plan to perform a unique, direct and precise measurement of a fine-structure transition in a heavy Li-like ion. Such a measurement will test state-of-the-art atomic structure calculations in strong fields. This endeavour will require that the existing infrastructure is complemented by a dedicated beamline for the XRL. In this paper, we will discuss the details of this project and outline a proof-of-principle experiment. (paper)

Recent Test Results of the Fast-Pulsed 4 T COS$\\Theta$ Dipole GSI 001

CERN Document Server

Moritz, G; Escallier, John; Ganetis, George; Jain, Animesh K; Marone, Andrew; Muratore, Joseph F; Thomas, Richard A; Wanderer, Peter; Auchmann, Bernard; de Maria, Riccardo; Wilson, Martin N; Russenschuck, Stephan

2005-01-01

For the FAIR-project at GSI a model dipole was built at BNL with the nominal field of 4 T and a nominal ramp rate of 1 T/s. The magnet design was similar to the RHIC dipole with some changes for loss reduction and better cooling. The magnet was already successfully tested in a vertical cryostat with good training behaviour. Cryogenic losses were measured and first results of field harmonics were published. However, for a better understanding of the cooling process quench currents at several ramp rates were investigated. Detailed measurements of the field harmonics at different ramp rates and at several cycles were performed. To separate the effects of the coil and the iron yoke the magnet was disassembled and tested as collared coil only. Recent test results will be presented.

Atomic collision studies at moderate projectile velocities using highly charged, decelerated heavy ions from the GSI-UNILAC

International Nuclear Information System (INIS)

Mokler, P.H.; Hoffmann, D.H.H.; Schoenfeldt, W.A.; Maor, D.

1984-01-01

Beams of highly ionized, very heavy atoms at moderate velocities have been produced at the UNILAC using the acceleration-stripping-deceleration method. The available ion species range from Kr 33+ to U 66+ in the energy region between 2 and 5 MeV/u. A survey on first experiments at GSI using these moderate velocity, few electron, heavy ion beams is given. The effectiveness of the method is demonstrated for Xesup(q+)-Xe collision experiments with 41 <= q <= 45. Results on vacancy transfer between inner quasimolecular levels for close collisions, and on distant collision electron capture are reported. (orig.)

Material-related issues at high-power and high-energy ion beam facilities

CERN Document Server

Bender, M.; Tomut, M.; Trautmann, C.

2015-01-01

When solids are exposed to energetic ions (MeV-GeV), their physical and chemical structure can be severely modified. The change is governed by ultrafast dynamical processes starting from the deposition of large energy densities, electronic excitation and ionization processes, and finally damage creation in the atomic lattice system. In many materials, each projectile creates a cylindrical track with a few nanometers in diameter and up to many μm in length. To study and monitor the creation of damage, the GSI irradiation facility dedicated to materials science provides different in-situ and on-line techniques such as high resolution microscopy, X-ray diffraction, optical absorption spectroscopy, thermal imaging and residual gas analysis. The irradiation experiments can be performed under various gas atmospheres and under cryogenic or elevated temperature.

The ASY-EOS experiment at GSI: investigating symmetry energy at supra-saturation densities

Directory of Open Access Journals (Sweden)

Russotto P.

2014-03-01

Full Text Available The elliptic-flow ratio of neutrons with respect to protons or light complex particles in reactions of heavy-ions at pre-relativistic energies has been proposed as an observable sensitive to the strength of the symmetry term of the nuclear equation of state at supra-saturation densities. The results obtained from the existing FOPI/LAND data for 197Au+197Au collisions at 400 MeV/nucleon in comparison with the UrQMD model simulations favoured a moderately soft symmetry term, but suffer from a considerable statistical uncertainty. These results have been confirmed by an independent analysis based on the Tübingen QMD simulations. In order to obtain an improved data set for Au+Au collisions and to extend the study to other systems, a new experiment was carried out at the GSI laboratory by the ASY-EOS collaboration. The present status of the data analysis is reported

Radiation damage to histones

International Nuclear Information System (INIS)

Mee, L.K.; Adelstein, S.J.

1985-01-01

The damage to histones irradiated in isolation is being elaborated to aid the identification of the crosslinking sites in radiation-induced DNA-histone adducts. Histones are being examined by amino acid analysis to determine the destruction of residues and by polyacrylamide gel electrophoresis to delineate changes in conformation. For the slightly lysine-rich histone, H2A, a specific attack on selective residues has been established, the aromatic residues, tyrosine and phenylalanine, and the heterocyclic residue, histidine, being significantly destroyed. In addition, a significant increase in aspartic acid was found; this may represent a radiation product from scission of the ring in the histidine residues. The similarity of the effects on residues in nitrous oxide-saturated and nitrogen-saturated solutions suggests that OH . and e/sub aq//sup -/ are equally efficient and selective in their attack. On gel electrophoresis degradation of the histone H2A was found to be greatest for irradiations in nitrous oxide-saturated solutions, suggesting CH . is the most effective radical for producing changes in conformation; O/sub 2//sup -/ was essentially ineffective. Other histones are being examined for changes in amino acid composition, conformation, and for the formation of radiation products

Present and Future Experiments with Stored Exotic Nuclei at GSI

International Nuclear Information System (INIS)

Geissel, H.

2009-01-01

Recent results and perspectives of experiments with stored exotic nuclei at GSI-FAIR will presented. An overview on the planned NUSTAR experiments will also presented. Relativistic exotic nuclei produced via projectile fragmentation and fission were separated in flight by the fragment separator FRS and injected into the storage-cooler ring ESR for accurate mass- and lifetime measurements. Direct mass measurements of electron-cooled exotic nuclei were performed using time-resolved Schottky spectrometry. Fragments with half-lives shorter than the time required for electron cooling have been investigated by time-of-flight measurements with the ESR being operated in the isochronous mode. This novel experimental technique gives access to all nuclei with half-lives down to the microsecond range and has been successfully applied. Lifetimes of stored bare and few-electron ions have been measured with the goal to study the beta-decay under ionization conditions prevailing in stellar plasma. For the first time the direct observation of bound-state beta decay has been achieved with 2 07T l fragments. The future project FAIR includes a new large-acceptance in-flight separator (Super-FRS) in combination with a new storage ring system (CR, NESR) which will be ideal tools to study exotic nuclei far from stability.(author)

Chapter 6: Fire damage of wood structures

Science.gov (United States)

B. Kukay; R.H. White; F. Woeste

2012-01-01

Depending on the severity, fire damage can compromise the structural integrity of wood structures such as buildings or residences. Fire damage of wood structures can incorporate several models that address (1) the type, cause, and spread of the fire, (2) the thermal gradients and fire-resistance ratings, and (3) the residual load capacity (Figure 6.1). If there is a...

Life assessment of aerospace structure using damage tolerance

International Nuclear Information System (INIS)

Anwar, W.; Khan, M.Z.

2007-01-01

Damage Tolerant Design plays a major role in the Aerospace Industry not only in the design of new structures and components but also their ongoing maintenance and support. Damage Tolerance Analysis (DT A) is a procedure that defines whether a crack can be sustained safely during the projected service life of the structure. Using this methodology, service life of an aerospace structure can be determined and may be extended by applying proper tooling and machining for repair. In this research the effect of damage increment on the convergence of the residual strength is investigated for a wing component of an aircraft. The stresses redistribution with damage growth is discussed. Simulation using Linear Elastic Fracture Mechanics (LEFM) laws are performed, those results the damage scenarios to be assessed in the real structural geometry and loading environment, using Stress Intensity Factors, Critical Crack Sizes and the Residual Strength of that component. Fatigue crack growth behaviour of the component is also investigated experimentally. The fatigue experiments were performed under constant stress amplitude loadings and constant amplitude loading with single overload. It has been observed that the computed fatigue curves fit well with the experimental results. (author)

Multiple Site Damage in Flat Panel Testing

National Research Council Canada - National Science Library

Shrage, Daniel

2000-01-01

This report aimed to experimentally verify analytical models that predict the residual strength of representative aircraft structures, such as wide panels, that are subjected to Multiple Site Damage (MSD...

Resolution of GSI B-56 - Emergency diesel generator reliability

International Nuclear Information System (INIS)

Serkiz, A.W.

1989-01-01

The need for an emergency diesel generator (EDG) reliability program has been established by 10 CFR Part 50, Section 50.63, Loss of All Alternating Current Power, which requires that licensees assess their station blackout coping and recovery capability. EDGs are the principal emergency ac power sources for avoiding a station blackout. Regulatory Guide 1.155, Station Blackout, identifies a need for (1) a nuclear unit EDG reliability level of at least 0.95, and (2) an EDG reliability program to monitor and maintain the required EDG reliability levels. NUMARC-8700, Guidelines and Technical Bases for NUMARC Initiatives Addressing Station Blackout at Light Water Reactors, also provides guidance on such needs. The resolution of GSI B-56, Diesel Reliability will be accomplished by issuing Regulatory Guide 1.9, Rev. 3, Selection, Design, Qualification, Testing, and Reliability of Diesel Generator Units Used as Onsite Electric Power Systems at Nuclear Plants. This revision will integrate into a single regulatory guide pertinent guidance previously addressed in R.G. 1.9, Rev. 2, R.G. 1.108, and Generic Letter 84-15. R.G. 1.9 has been expanded to define the principal elements of an EDG reliability program for monitoring and maintaining EDG reliability levels selected for SBO. In addition, alert levels and corrective actions have been defined to detect a deteriorating situation for all EDGs assigned to a particular nuclear unit, as well as an individual problem EDG

A simulation methodology of spacer grid residual spring deflection for predictive and interpretative purposes

International Nuclear Information System (INIS)

Kim, K. T.; Kim, H. K.; Yoon, K. H.

1994-01-01

The in-reactor fuel rod support conditions against the fretting wear-induced damage can be evaluated by spacer grid residual spring deflection. In order to predict the spacer grid residual spring deflection as a function of burnup for various spring designs, a simulation methodology of spacer grid residual spring deflection has been developed and implemented in the GRIDFORCE program. The simulation methodology takes into account cladding creep rate, initial spring deflection, initial spring force, and spring force relaxation rate as the key parameters affecting the residual spring deflection. The simulation methodology developed in this study can be utilized as an effective tool in evaluating the capability of a newly designed spacer grid spring to prevent the fretting wear-induced damage

Production of a pion in association with a high-Q2 dilepton pair in antiproton-proton annihilation at GSI-FAIR

International Nuclear Information System (INIS)

Lansberg, J. P.; Pire, B.; Szymanowski, L.

2007-01-01

We evaluate the cross section for pp→l + l - π 0 in the forward direction and for a large lepton pair invariant mass. In this kinematical region, the leading-twist amplitude factorizes into a short-distance matrix element, long-distance antiproton-distribution amplitudes, and proton to pion transition distribution amplitudes (TDAs). Using a modeling inspired from the chiral limit for these TDAs, we obtain a first estimate of this cross section, which demonstrates that this process can be measured at GSI-FAIR

Seismic damage sensing of bridge structures with TRIP reinforcement steel bars

Science.gov (United States)

Adachi, Yukio; Unjoh, Shigeki

2001-07-01

Intelligent reinforced concrete structures with transformation-induced-plasticity (TRIP) steel rebars that have self-diagnosis function are proposed. TRIP steel is special steel with Fe-Cr based formulation. It undergoes a permanent change in crystal structure in proportion to peak strain. This changes from non-magnetic to magnetic steel. By using the TRIP steel rebars, the seismic damage level of reinforced concrete structures can be easily recognized by measuring the residual magnetic level of the TRIP rebars, that is directly related to the peak strain during a seismic event. This information will be most helpful for repairing the damaged structures. In this paper, the feasibility of the proposed intelligent reinforced concrete structure for seismic damage sensing is experimentally studied. The relation among the damage level, peak strain of rebars, and residual magnetic level of rebars of reinforced concrete beams implemented with TRIP steel bars was experimentally studied. As the result of this study, this intelligent structure can diagnose accumulated strain/damage anticipated during seismic event.

Swift heavy ion induced modification of aliphatic polymers

International Nuclear Information System (INIS)

Hossain, Umme Habiba

2015-01-01

In this thesis, the high energy heavy ion induced modification of aliphatic polymers is studied. Two polymer groups, namely polyvinyl polymers (PVF, PVAc, PVA and PMMA) and fluoropolymers (PVDF, ETFE, PFA and FEP) were used in this work. Polyvinyl polymers were investigated since they will be used as insulating materials in the superconducting magnets of the new ion accelerators of the planned International Facility for Antiproton and Ion Research (FAIR) at the GSI Helmholtz-Centre of Heavy Ion Research (GSI) in Darmstadt. In order to study ion-beam induced degradation, all polymer foils were irradiated at the GSI linear accelerator UNILAC using several projectiles (U, Au, Sm, Xe) and experimentation sites (beam lines X0 and M3) over a large fluence regime (1 x 10 10 - 5 x 10 12 ions/cm 2 ). Five independent techniques, namely infrared (FT-IR) and ultraviolet-visible (UV-Vis) spectroscopy, residual gas analysis (RGA), thermal gravimetric analysis (TGA), and mass loss analysis (ML), were used to analyze the irradiated samples. FT-IR spectroscopy revealed that ion irradiation led to the decrease of characteristic band intensities showing the general degradation of the polymers, with scission of side groups and the main backbone. As a consequence of the structural modification, new bands appeared. UV-Vis transmission analysis showed an absorption edge shift from the ultraviolet region towards the visible region indicating double bond and conjugated double bond formation. On-line massspectrometric residual gas analysis showed the release of small gaseous fragment molecules. TGA analysis gave evidence of a changed thermal stability. With ML analysis, the considerable mass loss was quantified. The results of the five complementary analytical methods show how heavy ion irradiation changes the molecular structure of the polymers. Molecular degradation mechanisms are postulated. The amount of radiation damage is found to be sensitive to the used type of ionic species. While

Investigations on KONUS beam dynamics using the pre-stripper drift tube linac at GSI

Science.gov (United States)

Xiao, C.; Du, X. N.; Groening, L.

2018-04-01

Interdigital H-mode (IH) drift tube linacs (DTLs) based on KONUS beam dynamics are very sensitive to the rf-phases and voltages at the gaps between tubes. In order to design these DTLs, a deep understanding of the underlying longitudinal beam dynamics is mandatory. The report presents tracking simulations along an IH-DTL using the PARTRAN and BEAMPATH codes together with MATHCAD and CST. Simulation results illustrate that the beam dynamics design of the pre-stripper IH-DTL at GSI is sensitive to slight deviations of rf-phase and gap voltages with impact to the mean beam energy at the DTL exit. Applying the existing geometrical design, rf-voltages, and rf-phases of the DTL were re-adjusted. In simulations this re-optimized design can provide for more than 90% of transmission of an intense 15 emA beam keeping the reduction of beam brilliance below 25%.

The ASY-EOS experiment at GSI: Constraining the symmetry energy at supra-saturation densities

Directory of Open Access Journals (Sweden)

Russotto P.

2015-01-01

Full Text Available The elliptic-flow ratio of neutrons with respect to protons or light complex particles in reactions of heavy ions at pre-relativistic energies has been proposed as an observable sensitive to the strength of the symmetry term of the nuclear equation of state at supra-saturation densities. In the ASY-EOS experiment at the GSI laboratory, flows of neutrons and light charged particles were measured for 197Au+197Au, 96Zr+96Zr and 96Ru+96Ru collisions at 400 MeV/nucleon with the Large Area Neutron Detector LAND as part of a setup with several additional detection systems used for the event characterization. Flow results obtained for the Au+Au system, in comparison with predictions of the UrQMD transport model, confirm the moderately soft to linear density dependence of the symmetry energy deduced from the earlier FOPI-LAND data.

Prediction of fatigue damage in tapered laminates

DEFF Research Database (Denmark)

Raeis Hosseiny, Seyed Aydin; Jakobsen, Johnny

2017-01-01

Effective implementation of ply-drops configurations substantially improve the damage tolerant design of flexible and aero-elastic wind turbine blades. Terminating a number of layers for an optimized blade design creates local bending effects. Inter-laminar stress states in tapered areas give rise...... to delamination and premature structural failure. Precise calculation of the stress levels for embedded ply-drops is required to predict failure initiation within acceptable limits. Multi-axial stress states in orthotropic laminates subjected to diverse loading mechanisms nucleate microscopic cracks....... By increasing the cracks density, damage occurs when residual material properties reduce to a critical level. Residual strength and stiffness of simple laminates are assigned in a set of fatigue failure criteria to assess the remaining life of the components by increasing number of loading cycles. The mode...

Nuclear Structure of the Heaviest Elements – Investigated at SHIP-GSI

Directory of Open Access Journals (Sweden)

Heßberger Fritz Peter

2014-03-01

Full Text Available The quest for the heaviest nuclei that can exist is a basic topic in natural science as their stability is characterized by a delicate interplay of short range nuclear forces acting between the nucleons (protons and neutrons and long-range Coulomb forces acting solely between charged particles, i.e. the protons. As the stability of a nucleus is strongly correlated to its structure, understanding the nuclear structure of heaviest nuclei is presently a main challenge of experimental and theoretical investigations concerning the field of Superheavy Elements. At the velocity filter SHIP at GSI Darmstadt an extensive program on nuclear structure investigations has been started about a decade ago. The project covered both as well systematic investigations of single particle levels in odd-mass isotopes populated by α-decay as investigation of two- or fourquasi-particle states forming K isomers and was supplemented by direct mass measurements at SHIPTRAP and investigation of spontaneous fission properties. Recent experimental studies allowed to extend the systematics of low lying levels in N = 151 and N = 153 up to 255Rf and 259Sg, investigation of possible relations between nuclear structure and fission properties of odd-mass nuclei and investigation of shell strengths at N = 152 and towards N = 162.

Residual subsidence analysis after the end of coal mine work. Example from Lorraine Colliery, France

International Nuclear Information System (INIS)

Al Heib, M.; Nicolas, M.; Noirel, J.F.; Wojtkowiak, F.

2005-01-01

This paper describes the residual movements associated with the deep coal mines. The studied case relates to works located into Lorraine coal basin. The paper is divided into two sections. The first one describes subsidence phenomena, especially the residual phase in terms of amplitude, duration and localization. The second one focus on Morsbach case: the total and residual subsidence measurements will be analyzed and compared to the state of the art as well as the currant knowledge. The results of the analysis show that the duration of residual movements does not exceed 24 months and their amplitude is about 5% of total subsidence. We analyze also the declarations of the mining damage during and after the mining period. Damages occur, after this period are probably due to late observations. (authors)

Data-flow coupling and data-acquisition triggers for the PreSPEC-AGATA campaign at GSI

Energy Technology Data Exchange (ETDEWEB)

Ralet, D., E-mail: D.Ralet@gsi.de [Institut für Kernphysik, Technische Universität Darmstadt, Darmstadt (Germany); GSI, Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt (Germany); Pietri, S. [GSI, Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt (Germany); Aubert, Y. [Institut de Physique Nucléaire, Orsay (France); Bellato, M.; Bortolato, D. [Istituto Nazionale di Fisica Nucleare sezione di Padova, Padova (Italy); Brambilla, S.; Camera, F. [Istituto Nazionale di Fisica Nucleare sezione di Milano, Milano (Italy); Dosme, N. [CSNSM, Université Paris-Sud, Orsay (France); Gadea, A. [Instituto di Fisica Corpuscular, Valencia (Spain); Gerl, J. [GSI, Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt (Germany); Golubev, P. [Department of Physics, Lund University, Lund (Sweden); Grave, X. [CSNSM, Université Paris-Sud, Orsay (France); Johansson, H.T. [Chalmers University of Technology, Göteborg (Sweden); Karkour, N.; Korichi, A. [CSNSM, Université Paris-Sud, Orsay (France); Kurz, N. [GSI, Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt (Germany); Lafay, X.; Legay, E.; Linget, D. [CSNSM, Université Paris-Sud, Orsay (France); Pietralla, N. [Institut für Kernphysik, Technische Universität Darmstadt, Darmstadt (Germany); GSI, Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt (Germany); and others

2015-06-21

The PreSPEC setup for high-resolution γ-ray spectroscopy using radioactive ion beams was employed for experimental campaigns in 2012 and 2014. The setup consisted of the state of the art Advanced GAmma Tracking Array (AGATA) and the High Energy γ deteCTOR (HECTOR+) positioned around a secondary target at the final focal plane of the GSI FRagment Separator (FRS) to perform in-beam γ-ray spectroscopy of exotic nuclei. The Lund York Cologne CAlorimeter (LYCCA) was used to identify the reaction products. In this paper we report on the trigger scheme used during the campaigns. The data-flow coupling between the Multi-Branch System (MBS) based Data AcQuisition (DAQ) used for FRS-LYCCA and the “Nouvelle Acquisition temps Réel Version 1.2 Avec Linux” (NARVAL) based acquisition system used for AGATA are also described.

Specific chemical and structural damage to proteins produced by synchrotron radiation.

Science.gov (United States)

Weik, M; Ravelli, R B; Kryger, G; McSweeney, S; Raves, M L; Harel, M; Gros, P; Silman, I; Kroon, J; Sussman, J L

2000-01-18

Radiation damage is an inherent problem in x-ray crystallography. It usually is presumed to be nonspecific and manifested as a gradual decay in the overall quality of data obtained for a given crystal as data collection proceeds. Based on third-generation synchrotron x-ray data, collected at cryogenic temperatures, we show for the enzymes Torpedo californica acetylcholinesterase and hen egg white lysozyme that synchrotron radiation also can cause highly specific damage. Disulfide bridges break, and carboxyl groups of acidic residues lose their definition. Highly exposed carboxyls, and those in the active site of both enzymes, appear particularly susceptible. The catalytic triad residue, His-440, in acetylcholinesterase, also appears to be much more sensitive to radiation damage than other histidine residues. Our findings have direct practical implications for routine x-ray data collection at high-energy synchrotron sources. Furthermore, they provide a direct approach for studying the radiation chemistry of proteins and nucleic acids at a detailed, structural level and also may yield information concerning putative "weak links" in a given biological macromolecule, which may be of structural and functional significance.

Use of demolition residues construction in soil-lime bricks

International Nuclear Information System (INIS)

Figueiredo, S.S.; Silva, C.G.; Silva, I.A.; Neves, G.A.

2011-01-01

Besides being responsible for several environmental damage caused by its residues, the construction industry is also considered the greatest natural resources consumer. When finely ground, such residues can exhibit cementing properties, which may replace part of the lime used in the manufacture of soil-lime bricks. This study aimed to verify the viability of using demolition residues (DR) in soil-lime bricks without structural function. For this, test specimens were prepared using mixes in a 1:10 ratio of lime:soil and embedding residue in partial replacement of lime in the proportions of 25%, 50% and 75%. The test specimens were submitted to curing periods of 28 and 52 days, then it was determined the compression strength. The results showed that when embedded on moderate percentages, demolition residues construction can be used in the production of soil-lime bricks. (author)

PENGARUH KOMPENSASI DAN LINGKUNGAN KERJA TERHADAP KINERJA KARYAWAN DIVISI QIP PT. GSI CIANJUR

Directory of Open Access Journals (Sweden)

Suharyanto Suharyanto

2014-12-01

Full Text Available The role of human resource management is continously improved to enhance the performance of employees. PT GSI, as one of Indonesian company producing shoe products to meet demand from all around the world, needs employees with high performance. On the other side, the employees need reasonable compensation and safe work environments. This research is conducted to investigate the relationships and the effects of the compensation and work environment variables on the job performance. Using causal descriptive research method, samples of 77 units are randomly taken from 328 labors at the Quality Inspection Production Divison. The questionaire comprising eighteen questions is applied to explore the employee minds and perceptions on the relationships and effects of the compensation and work environment variables toward the job performance variable. The result of this research shows that compensation (X1 and work environment (X2 variables simultanously effect to the job performance variable (Y. The linier regression equation constructed is represented by Y = 4,375 - 0,181X1 + 0,382X2.

Fatigue damage monitoring of structural aluminum alloys

Directory of Open Access Journals (Sweden)

С.Р. Ігнатович

2004-01-01

Full Text Available  Results of the experiments directed on creation of a new tool method of fatigue damage diagnostics and an estimation of a residual life of aviation designs are presented. It is shown, that the defo rmation relief formed on a surface of cladding  layer of sheets of constructional alloys Д-16АТ, 2024-Т3, 7075-Т6  can be considered as the metal damage indicator  under cyclically repeating loadings.

Evaluation of residual strength in the basalt fiber reinforced composites under impact damage

Science.gov (United States)

Kim, Yun-Hae; Lee, Jin-Woo; Moon, Kyung-Man; Yoon, Sung-Won; Baek, Tae-Sil; Hwang, Kwang-Il

2015-03-01

Composites are vulnerable to the impact damage by the collision as to the thickness direction, because composites are being manufactured by laminating the fiber. The understanding about the retained strength after the impact damage of the material is essential in order to secure the reliability of the structure design using the composites. In this paper, we have tried to evaluate the motion of the material according to the kinetic energy and potential energy and the retained strength after impact damage by testing the free fall test of the basalt fiber reinforced composite in the limelight as the environment friendly characteristic.

Photoexcited riboflavin induces oxidative damage to human serum albumin

Science.gov (United States)

Hirakawa, Kazutaka; Yoshioka, Takuto

2015-08-01

Photoexcited riboflavin induced damage of human serum albumin (HSA), a water soluble protein, resulting in the diminishment of fluorescence from the tryptophan residue. Because riboflavin hardly photosensitized singlet oxygen generation and sodium azide, a singlet oxygen quencher, did not inhibit protein damage, electron transfer-mediated oxidation of HSA was speculated. Fluorescence lifetime of riboflavin was not affected by HSA, suggesting that the excited triplet state of riboflavin is responsible for protein damage through electron transfer. In addition, the preventive effect of xanthone derivatives, triplet quenchers, on photosensitized protein damage could be evaluated using this photosensitized reaction system of riboflavin and HSA.

The E052 - GSI Experiment, Deceleration of highly charged ions by crystal channeling. (Technical notes)

International Nuclear Information System (INIS)

Kirsch, R.

2003-01-01

The report on the E052 - GSI Experiment, devoted to 'Deceleration of highly charged ions by crystal channeling' present the technical notes and the status of this experiment in 2003. The report contains 13 sections and two annexes. The sections deal with the following issues: 1. File system of the 'PC monitor' for E052 - GSI Experiment in 2003; 2. Parameters of the 'PC monitor' file system; 3. Operation of the two PCs; 3.1. Layout of goniometer remote control; 3.2. 'PC motors' side by the beam hall; 3.3. RS232 connection cabling; 3.4. RS232 configuration on the COM1 ports of the two PCs; 4. Motor connection; 4.1. SubD-25 acquisition PC monitor arm on 'COM1'; 4.2. Motors step by step feeding side SubD-25 on 'COM1'; 4.3. Distribution of digital step by step control signals; 4.5. Upper an lower goniometer connection; 4.6. Rotation and inclination outer goniometer connection; 4.7. Ultra vacuum inner rotation and inclination connection; 5. Motor characteristics; 5.1. Upstream and downstream; 5.2. Rotation; 5.3 Inclination; 5.4. Feedings; 6. Goniometer in-beam positioning; 6.1. Height fine motor positioning; 6.2. Side manual positioning; 7. Goniometer movements; 8. Crystals and electron detection; 8.1. General layout; 8.2. 1 μm Si(100) crystal; 8.3. 33 μm Si(100) crystal; 8.4. Crystal mounting; 8.5. Electron detection; 9. Reference laser positioning of angular movements; 10. Beam track and collimators upstream the target; 11. User manual - Monitoring programme; 11.Start scanning program (GSIscan.exe); 11.2. SCANNING the crystal (Scan Control window); 11.3. MOVING THE GONIOMETER MANUALY (goniometer control window); 11.4. USING THE COUNTERS (counter display window); 11.5. MULTISCALER PLOT DISPLAY; 11.6. SELECT ACTIVE PLOT; 11.7. CURSORS; 11.8. STATISTICS; 11.9. Y SCALE change; 11.10. PLOT view and hide counter; 11.11. SAVE multiscaler spectra; 11.12. PRINT plot; 12. Simplified acquisition electronic setup; 13. The 'PC motors' software; 13.1. The code structure; 13

Protein damage and repair controlling seed vigor and longevity.

Science.gov (United States)

Ogé, Laurent; Broyart, Caroline; Collet, Boris; Godin, Béatrice; Jallet, Denis; Bourdais, Gildas; Job, Dominique; Grappin, Philippe

2011-01-01

The formation of abnormal isoaspartyl residues derived from aspartyl or asparaginyl residues is a major source of spontaneous protein misfolding in cells. The repair enzyme protein L: -isoaspartyl methyltransferase (PIMT) counteracts such damage by catalyzing the conversion of abnormal isoaspartyl residues to their normal aspartyl forms. Thus, this enzyme contributes to the survival of many organisms, including plants. Analysis of the accumulation of isoaspartyl-containing proteins and its modulation by the PIMT repair pathway, using germination tests, immunodetection, enzymatic assays, and HPLC analysis, gives new insights in understanding controlling mechanisms of seed longevity and vigor.

The energy overcompensating disintegrations of residual target nuclei damaged in hadron-nucleus collisions

International Nuclear Information System (INIS)

Strugalski, Z.

1995-01-01

Massive target nuclei damaged in hadron-nucleus collisions at high energies are used to disintegrate into nuclear fragments. In many cases such breakup is egzoergic - some portion of nuclear energy is released; this portion should be overcompensating the energy used for the nuclear damage, in some cases. 30 refs

A pulsed supersonic gas jet target for precision spectroscopy at the HITRAP facility at GSI

Science.gov (United States)

Tiedemann, D.; Stiebing, K. E.; Winters, D. F. A.; Quint, W.; Varentsov, V.; Warczak, A.; Malarz, A.; Stöhlker, Th.

2014-11-01

A pulsed supersonic gas jet target for experiments at the HITRAP facility at the GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt has been designed and built as a multi-purpose installation for key experiments on fundamental atomic physics in strong fields. This setup is currently installed at the Institut für Kernphysik of Goethe-University, Frankfurt am Main (IKF), in order to explore its operation prior to its installation at the HITRAP facility. Design and performance of the target are described. The measured target densities of 5.9×1012 atoms/cm3 for helium and 8.1×1012 atoms/cm³ for argon at the stagnation pressure of 30 bar match the required values. The target-beam diameter of 0.9 mm and the pulsed operation mode (jet built-up-time ≤15 ms) are well suited for the use at HITRAP.

Ovalbumin with Glycated Carboxyl Groups Shows Membrane-Damaging Activity

Directory of Open Access Journals (Sweden)

Ching-Chia Tang

2017-02-01

Full Text Available The aim of the present study was to investigate whether glycated ovalbumin (OVA showed novel activity at the lipid-water interface. Mannosylated OVA (Man-OVA was prepared by modification of the carboxyl groups with p-aminophenyl α-dextro (d-mannopyranoside. An increase in the number of modified carboxyl groups increased the membrane-damaging activity of Man-OVA on cell membrane-mimicking vesicles, whereas OVA did not induce membrane permeability in the tested phospholipid vesicles. The glycation of carboxyl groups caused a notable change in the gross conformation of OVA. Moreover, owing to their spatial positions, the Trp residues in Man-OVA were more exposed, unlike those in OVA. Fluorescence quenching studies suggested that the Trp residues in Man-OVA were located on the interface binds with the lipid vesicles, and their microenvironment was abundant in positively charged residues. Although OVA and Man-OVA showed a similar binding affinity for lipid vesicles, the lipid-interacting feature of Man-OVA was distinct from that of OVA. Chemical modification studies revealed that Lys and Arg residues, but not Trp residues, played a crucial role in the membrane-damaging activity of Man-OVA. Taken together, our data suggest that glycation of carboxyl groups causes changes in the structural properties and membrane-interacting features of OVA, generating OVA with membrane-perturbing activities at the lipid-water interface.

Conceptual design and performance study for the first implementation of AGATA at the in-flight RIB facility of GSI

Science.gov (United States)

Domingo-Pardo, C.; Bazzacco, D.; Doornenbal, P.; Farnea, E.; Gadea, A.; Gerl, J.; Wollersheim, H. J.; Agata Collaboration

2012-12-01

The main objective of the Advanced GAmma Tracking Array (AGATA) is the investigation of the structure of exotic nuclei at the new generation of RIB facilities. As part of the preparatory phase for FAIR-NUSTAR, AGATA is going to be installed at the FRS fragmentation facility of the GSI centre for an experimental campaign to be performed in 2012 and 2013. Owing to its γ-ray tracking capabilities and the envisaged enhancement in resolving power, a series of in-flight γ-ray spectroscopy experiments are being planned. The present work describes the conceptual design of this first implementation of AGATA at GSI-FRS, and provides information about the expected performance figures. According to the characteristics of each particular experiment, it is foreseen that the target-array distance is adjusted in order to achieve the optimum compromise between detection efficiency and energy resolution, or to cover an specific angular range of the emitted electromagnetic radiation. Thus, a comprehensive Monte Carlo study of the detection sensitivity in terms of photopeak efficiency, resolution and peak-to-total ratio, as a function of the target-array distance is presented. Several configurations have been investigated, and MC-calculations indicate that a remarkable enhancement in resolving power can be achieved when double-cluster AGATA detectors are developed and implemented. Several experimental effects are also investigated. This concerns the impact of passive materials between the target and the array, the angular distribution of the detection efficiency and the influence of target thickness effects and transition lifetimes in the attainable detection sensitivity. A short overview on half-life measurements via lineshape effects utilizing AGATA is also presented.

Proliferative compensation of residual radiation damage in the compartment of hematopoietic early progenitor cells of the mouse

International Nuclear Information System (INIS)

Huebner, G.E.; Wangenheim, K.H. von; Feinendegen, L.E.

1984-01-01

The rate of cell entry from the compartment of hematopoietic early progenitor cells into differentiation was determined in sublethally irradiated mice. By use of the criterion of repopulating ability, transplantation of 5-( 125 I) iodo-2'-deoxyuridine labeled bone marrow cells into fatally irradiated syngeneic recipients allows to measure the relative number of early progenitor cells lodging in the spleen and the turnover of these cells in the donors. Following 450 rad the relative number of transplantable early progenitor cells in S-phase recovers to normal within 2 weeks and stabilizes after 5 weeks. At this time, the labeled progenitors turn over with a half-time of 1.4-2.2 days; the respective times for unirradiated mice are 1.5-1.8 days. This, quantitative and qualitative residual radiation damage that is known to exist in the compartment of CFU-S, is disguised within 2-5 weeks after irradiation by proliferative compensation in the entirety of early hemopoietic precursor cells which are here defined by their capacity of selfrenewal and delivery of differentiated cells and of seeding to spleens of lethally irradiated recipients. (orig.)

Effect of residual stresses on the reliability of components under fatigue

International Nuclear Information System (INIS)

Ruestenberg, I.

1995-01-01

The assurance of the reliability of mechanical components relative to a variety of failure mechanisms is of decisive technical, industrial, and economic importance. In this dissertation, the reliability, i.e. the probability that the lifetime does not fall below a given value, is examined with respect to the particularly important failure mechanisms of fracture and fatigue. The general problem of uniaxial fatigue is studied on the basis of both continuum damage mechanics and crack mechanics. In particular, the mechanisms of crack initiation, as characterized by the Coffin-Manson-Neuber local strain-life equations for notched components as well as the mechanism of crack growth, as governed by the Paris-Erdogang relation, are taken into account. The nonlinear fatigue damage accumulation process for components subjected to general, cyclic loading histories is modeled by a multilinear damage law which allows, in principle, to characterize the subsequent activation of different fatigue mechanisms. Explicit equations are developed for quintuple-, quadruple-, and triple-linear damage accumulation. Particularly promising appears the triple-linear damage approach which allows, in principle, the identification of a nucleation, an initiation, and a final growth stage up to rupture of fatigue cracks. The beneficial effect of intentionally induced compressive residual stresses on the lifetime of the component is investigated. To this end, an elasto-plastic contact problem, based on Prandtl-Reuss' constitutive equations, is numerically solved, and the residual stress field, as it is typically produced by the mechanical process of cold rolling, is established. Assessments of the effect of adaptation, i.e. the subsequent reduction of the residual stresses due to cyclic in-service loading as well as of the effect of unavoidable surface roughness, introduced by manufacturing processes like forging, are carried out. (author) figs., tabs., refs

Residual stress evaluation and fatigue life prediction in the welded joint by X-ray diffraction

International Nuclear Information System (INIS)

Yoo, Keun Bong; Kim, Jae Hoon

2009-01-01

In the fossil power plant, the reliability of the components which consist of the many welded parts depends on the quality of welding. The residual stress is occurred by the heat flux of high temperature during weld process. This decreases the mechanical properties as the strength of fatigue and fracture or occurs the stress corrosion cracking and fatigue fracture. The residual stress of the welded part in the recently constructed power plants has been the cause of a variety of accidents. The objective of this study is measurement of the residual stress by X-ray diffraction method and to estimate the feasibility of this application for fatigue life assessment of the high-temperature pipeline. The materials used for the study is P92 steel for the use of high temperature pipe on super critical condition. The test results were analyzed by the distributed characteristics of residual stresses and the Full Width at Half Maximum intensity (FWHM) in x-ray diffraction intensity curve. Also, X-ray diffraction tests using specimens simulated low cycle fatigue damage were performed in order to analyze fatigue properties when fatigue damage conditions become various stages. As a result of X-ray diffraction tests for specimens simulated fatigue damages, we conformed that the ratio of the FWHM due to fatigue damage has linear relationship with fatigue life ratio algebraically. From this relationships, it was suggested that direct expectation of the life consumption rate was feasible.

Integrated geomechanical modelling for deep subsurface damage

NARCIS (Netherlands)

Wees, J.D. van; Orlic, B.; Zijl, W.; Jongerius, P.; Schreppers, G.J.; Hendriks, M.

2001-01-01

Government, E&P and mining industry increasingly demand fundamental insight and accurate predictions on subsurface and surface deformation and damage due to exploitation of subsurface natural resources, and subsurface storage of energy residues (e.g. CO2). At this moment deformation is difficult to

Residual Cdk1/2 activity after DNA damage promotes senescence

Czech Academy of Sciences Publication Activity Database

Müllers, E.; Cascales, H.S.; Burdová, Kamila; Macůrek, Libor; Lindqvist, A.

2017-01-01

Roč. 16, č. 3 (2017), s. 575-584 ISSN 1474-9726 R&D Projects: GA ČR GA13-18392S Institutional support: RVO:68378050 Keywords : Cdk1 * Cdk2 * cell cycle * checkpoint recovery * DNA damage response * G2phase * p21 * senescence Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Biochemistry and molecular biology

The method for measuring residual stress in stainless steel pipes

International Nuclear Information System (INIS)

Shimov, Georgy; Rozenbaum, Mikhail; Serebryakov, Alexandr; Serebryakov, Andrey

2016-01-01

The main reason of appearance and growth of corrosion damages of the nuclear steam generator heat exchanger tubes is the process of stress-corrosion cracking of metal under the influence of residual tensile stress. Methods used in the production for estimating residual stresses (such as a method of ring samples) allow measuring only the average tangential stress of the pipe wall. The method of ring samples does not allow to assess the level of residual stress in the surface layer of the pipe. This paper describes an experimental method for measuring the residual stresses on the pipe surface by etching a thin surface layer of the metal. The construction and working principle of a trial installation are described. The residual stresses in the wall of the tubes 16 × 1.5 mm (steel AISI 321) for nuclear steam generators is calculated. Keywords: heat exchange pipes, stress corrosion cracking, residual stresses, stress distribution, stress measurement.

Numerical simulation of residual stress in piping components at Framatome-ANP

International Nuclear Information System (INIS)

Gilies, P.; Franco, C.; Cipiere, M.-F.; Ould, P.

2005-01-01

Numerous manufacturing processes induce residual stresses and distortions in piping components and associated welds: quenching of cast pipings, machining and welding. In Pressurized Water Reactors, most of the components have a large thickness for sustaining pressure and distortions are a minor source of concern. This is not the case for residual stresses which may have a strong influence on several type of damage such as fatigue, corrosion, brittle fracture. In low toughness components, residual stress fields may contribute to ductile tearing initiation. These potential damages are mitigated after welding by stress relief heat treatment, which is applied in a systematic manner to ferritic components of the primary system in nuclear reactors. This treatment is not applied on austenitic piping for which the heat treatment temperature is limited due to the risk of sensitization and residual stresses are difficult to eliminate completely. Since on site measurements are costly and difficult to perform, numerical simulation appears to be an attractive tool for estimating residual stress distributions. Framatome-ANP is working on modelling manufacturing processes with that purpose in mind. This paper presents three kinds of applications illustrating efforts on welding, quenching and machining simulation. First a comparison is shown between computations and measurements of residual stress induced by welding of a dissimilar weld metal junction. Then numerical simulations of quenching of a cast stainless steel nozzle are presented. Finally quenching followed by machining and grinding of this cast component are considered in a full simulation of the manufacturing process. Computed distortions and residual stresses are compared with experimental measurements at different stages of the manufacturing process. (authors)

Breakwater stability with damaged single layer armour units

OpenAIRE

De Rover, R.; Verhagen, H.J.; Van den Berge, A.; Reedijk, B.

2008-01-01

The effect of single layer interlocking armour unit breakage on the hydraulic armour layer stability and potential damage progression is addressed in this paper. A 2-dimensional scale model of a rubble mound breakwater with an armour layer consisting of Xbloc armour units was tested. The residual armour layer stability with broken units was determined. The armour unit displacement and damage progression was assessed. According to the test series breakage of the single layer armour units has a...

C-130: Results of center wing residual strength and crack propagation test program

Science.gov (United States)

Reeder, F. L.; Dirkin, W. J.; Snider, H. L.

1971-01-01

Fourteen C-130 airplane center wings which had experienced from approximately 4,000 to 13,000 hours of flight service and its associated fatigue damage were tested to destruction, seven in upbending and seven in downbending. Six wings were tested directly for static residual strength in the fatigue-damaged condition as received from field service. The other eight wings were tested in crack propagation cyclic testing at a prescribed stress level for a maximum of 10,000 cycles. Then the stress level was reduced and testing was continued up to a maximum of 20,000 total cycles. Cyclic testing was performed with constant-amplitude stresses at a stress ratio of +0.1. Maximum cyclic skin stresses were approximately 18,000 psi. At the conclusion of cyclic testing, a static test to destruction was conducted to determine the residual strength of each fatigue-damaged specimen.

Quantification of stress-induced damage and post-fire response of 5083 aluminum alloy

International Nuclear Information System (INIS)

Chen, Y.; Puplampu, S.B.; Summers, P.T.; Lattimer, B.Y.; Penumadu, D.; Case, S.W.

2015-01-01

One of the major concerns regarding the use of lightweight materials in ship construction is the response of those materials to fire scenarios, including the residual structural performance after a fire event. This paper presents a study on creep damage evolution in 5083 marine-grade aluminum alloy and its impact on residual mechanical behavior. Tests conducted at 400 °C and pre-selected tensile stress levels were interrupted at target amplitudes of accumulated engineering creep strains to investigate the stress-induced damage using ex-situ characterization. Two-dimensional optical and electron microscopy and three-dimensional X-ray tomography were utilized on samples extracted from these test specimens to characterize the external and internal creep damage. The stress-induced damage is primarily manifested as cavitation and dynamic microstructural evolution. Cavitation morphology, orientation and grain structure evolution were investigated on three perpendicular sample surfaces. A 3D examination of the damage state provided consistent damage information to that obtained from the 2D analysis. The post-fire mechanical properties were also evaluated and linked to the microstructural change. The competing processes of cavitation and grain structure evolution were investigated to develop an understanding of the stress-induced damage associated with high temperature creep

Quantification of stress-induced damage and post-fire response of 5083 aluminum alloy

Energy Technology Data Exchange (ETDEWEB)

Chen, Y., E-mail: yanyun@vt.edu [Department of Engineering Science & Mechanics, Virginia Tech, Blacksburg, VA 24061 (United States); Puplampu, S.B. [Department of Civil and Environmental Engineering, University of Tennessee, Knoxville, TN 37996 (United States); Summers, P.T.; Lattimer, B.Y. [Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA 24061 (United States); Penumadu, D. [Department of Civil and Environmental Engineering, University of Tennessee, Knoxville, TN 37996 (United States); Case, S.W. [Department of Engineering Science & Mechanics, Virginia Tech, Blacksburg, VA 24061 (United States)

2015-08-12

One of the major concerns regarding the use of lightweight materials in ship construction is the response of those materials to fire scenarios, including the residual structural performance after a fire event. This paper presents a study on creep damage evolution in 5083 marine-grade aluminum alloy and its impact on residual mechanical behavior. Tests conducted at 400 °C and pre-selected tensile stress levels were interrupted at target amplitudes of accumulated engineering creep strains to investigate the stress-induced damage using ex-situ characterization. Two-dimensional optical and electron microscopy and three-dimensional X-ray tomography were utilized on samples extracted from these test specimens to characterize the external and internal creep damage. The stress-induced damage is primarily manifested as cavitation and dynamic microstructural evolution. Cavitation morphology, orientation and grain structure evolution were investigated on three perpendicular sample surfaces. A 3D examination of the damage state provided consistent damage information to that obtained from the 2D analysis. The post-fire mechanical properties were also evaluated and linked to the microstructural change. The competing processes of cavitation and grain structure evolution were investigated to develop an understanding of the stress-induced damage associated with high temperature creep.

Research items regarding seismic residual risk evaluation

Energy Technology Data Exchange (ETDEWEB)

NONE

2013-08-15

After learning the Fukushima Dai-ichi NPP severe accidents in 2011, the government investigation committee proposed the effective use of probabilistic safety assessment (PSA), and now it is required to establish new safety rules reflecting the results of probabilistic risk assessment (PRA) and proposed severe accident measures. Since the Seismic Design Guide has been revised on September 19, 2006, JNES has been discussing seismic PRA (Levels 1-3) methods to review licensees' residual risk assessment while preparing seismic PRA models. Meanwhile, new safety standards for light water reactors are to be issued and enforced on July 2013, which require the residual risk of tsunami, in addition to earthquakes, should be lowered as much as possible. The Fukushima accidents raised the problems related to risk assessment, e.g. approaches based on multi-hazard (earthquake and tsunami), multi-unit, multi-site, and equipment's common cause failure. This fiscal year, while performing seismic and/or tsunami PRA to work on these problems, JNES picked up the equipment whose failure greatly contribute to core damage, surveyed accident management measures on those equipment as well as effectiveness to reduce core damage probability. (author)

Effects of oil and oil burn residues on seabird feathers

DEFF Research Database (Denmark)

Fritt-Rasmussen, Janne; Linnebjerg, Jannie Fries; Sørensen, Martin X.

2016-01-01

It is well known, that in case of oil spill, seabirds are among the groups of animals most vulnerable. Even small amounts of oil can have lethal effects by destroying the waterproofing of their plumage, leading to loss of insulation and buoyancy. In the Arctic these impacts are intensified....... To protect seabirds, a rapid removal of oil is crucial and in situ burning could be an efficient method. In the present work exposure effects of oil and burn residue in different doses was studied on seabird feathers from legally hunted Common eider (Somateria mollissima) by examining changes in total weight...... of the feather and damages on the microstructure (Amalgamation Index) of the feathers before and after exposure. The results of the experiments indicate that burn residues from in situ burning of an oil spill have similar or larger fouling and damaging effects on seabird feathers, as compared to fresh oil....

Fragmentation of a 500 MeV/nucleon 86Kr beam, investigated at the GSI projectile fragment separator

International Nuclear Information System (INIS)

Weber, M.; Donzaud, C.; Geissel, H.; Grewe, A.; Lewitowicz, M.; Magel, A.; Mueller, A.C.; Nickel, F.; Pfuetzner, M.; Piechaczek, A.; Pravikoff, M.; Roeckl, E.; Rykaczewski, K.; Saint-Laurent, M.G.; Schall, I.; Stephan, C.; Tassan-Got, L.; Voss, B.

1993-10-01

Production cross-sections and longitudinal momentum distributions have been investigated for reactions between a 500 MeV/nucleon 86 Kr beam and beryllium, copper and tantalum targets. Fragments in a wide A/Z range were studied at the projectile-fragment separator FRS at GSI. The experimental production cross-sections have been used for testing the predictions obtained from a semi-empirical parameterization, a statistical abrasion model and an intranuclear-cascade model. The present study allows to extrapolate the production cross-sections towards very neutron-rich isotopes such as the doubly magic nucleus 78 Ni. For fragments close to the projectile the measured longitudinal momentum distributions agrees qualitatively with a semi-empirical parameterization, which is based on the two-step picture of the fragmentation process. The momentum widths of lighter fragments, however, show deviations from this simple picture. (orig.)

GSI Helmholz Centre for Heavy Ion Research - ALFA: Next generation concurrent framework for ALICE and FAIR experiments

CERN Multimedia

CERN. Geneva

2015-01-01

FAIR is a new, unique international accelerator facility for the research with antiprotons and ions. It is being built at the GSI Darmstadt in Hesse, Germany. The commonalities between the ALICE and FAIR experiments and their computing requirements led to the development of a common software framework in an experiment independent way; ALFA (ALICE-FAIR framework). ALFA is designed for high quality parallel data processing and reconstruction on heterogeneous computing systems. It provides a data transport layer and the capability to coordinate multiple data processing components. ALFA is a flexible, elastic system which balances reliability and ease of development with performance by using a message based multi-processing in addition to multi-threading. The framework allows for usage of heterogeneous computing architectures by offloading (portions of code are accelerated on the device) or natively (where the full program is executed on the device ).

H-/H∞ structural damage detection filter design using an iterative linear matrix inequality approach

International Nuclear Information System (INIS)

Chen, B; Nagarajaiah, S

2008-01-01

The existence of damage in different members of a structure can be posed as a fault detection problem. It is also necessary to isolate structural members in which damage exists, which can be posed as a fault isolation problem. It is also important to detect the time instants of occurrence of the faults/damage. The structural damage detection filter developed in this paper is a model-based fault detection and isolation (FDI) observer suitable for detecting and isolating structural damage. In systems, possible faults, disturbances and noise are coupled together. When system disturbances and sensor noise cannot be decoupled from faults/damage, the detection filter needs to be designed to be robust to disturbances as well as sensitive to faults/damage. In this paper, a new H - /H ∞ and iterative linear matrix inequality (LMI) technique is developed and a new stabilizing FDI filter is proposed, which bounds the H ∞ norm of the transfer function from disturbances to the output residual and simultaneously does not degrade the component of the output residual due to damage. The reduced-order error dynamic system is adopted to form bilinear matrix inequalities (BMIs), then an iterative LMI algorithm is developed to solve the BMIs. The numerical example and experimental verification demonstrate that the proposed algorithm can successfully detect and isolate structural damage in the presence of measurement noise

Benfotiamine Protects against Peritoneal and Kidney Damage in Peritoneal Dialysis

OpenAIRE

Kihm, Lars P.; Müller-Krebs, Sandra; Klein, Julia; Ehrlich, Gregory; Mertes, Laura; Gross, Marie-Luise; Adaikalakoteswari, Antonysunil; Thornalley, Paul J.; Hammes, Hans-Peter; Nawroth, Peter P.; Zeier, Martin; Schwenger, Vedat

2011-01-01

Residual renal function and the integrity of the peritoneal membrane contribute to morbidity and mortality among patients treated with peritoneal dialysis. Glucose and its degradation products likely contribute to the deterioration of the remnant kidney and damage to the peritoneum. Benfotiamine decreases glucose-induced tissue damage, suggesting the potential for benefit in peritoneal dialysis. Here, in a model of peritoneal dialysis in uremic rats, treatment with benfotiamine decreased peri...

Three-dimensional finite element analysis of residual magnetic field for ferromagnets under early damage

International Nuclear Information System (INIS)

Yao, Kai; Shen, Kai; Wang, Zheng-Dao; Wang, Yue-Sheng

2014-01-01

In this study, 3D finite element analysis is presented by calculating the residual magnetic field signals of ferromagnets under the plastic deformation. The contour maps of tangential and normal RMF gradients are given, and the 3D effect is discussed. The results show that the tangential peak–peak amplitude and normal peak–vale amplitude are remarkably different in 2D and 3D simulations, but the tangential peak–peak width and normal peak–vale width are similar. Moreover, some key points are capable of capturing the plastic-zone shape, especially when the lift-off is small enough. The present study suggests an effective defect identification method with Metal magnetic memory (MMM) technique. - Highlights: • Three-dimensional (3D) finite element analysis is presented by calculating the residual magnetic field signals of ferromagnets under the plastic deformation. • The contour maps of gradients of the tangential and normal residual magnetic fields are given, and the 3D effect is discussed. • The present study suggests an effective defect identification method with metal magnetic memory technique

Application of backpropagation neural networks to evaluate residual properties of thermally damaged concrete

International Nuclear Information System (INIS)

Vasconcelos, W.L.; Shigaki, Y.; Tolentino, E.

2009-01-01

In this work it was analyzed the residual performance of Portland cement concretes, when cold after heat-treated up to 600 deg C. Granite-gneiss was used in the three concrete mix proportions as the coarse aggregate, and river sand with finesses modulus of 2.7 as the fine aggregate. Ultrasonic pulse tests were performed on all the specimens and ultrasonic dynamic modulus were obtained. An artificial neural network of the backpropagation type was trained to evaluate and apply models in predicting residual properties of Portland cement concretes. The input layer for both models consists of an external layer input vector of the temperature. The hidden layer has two processing units with hyperbolic tangent sigmoid transfer functions (tansig for short), and the output layer contains one processing unit that represents the network's output (ultrasonic pulse velocity or modulus of elasticity) for each input vector. The training phase of the network converged for reasonable results after 5.000 epochs approximately, resulting in mean squared errors less than 0.02 for the normalized data. The neural network developed for modeling residual properties of Portland cement concretes was shown to be efficient in both the training phase and the test. From the results reasonable predictions could be made for the ultrasonic pulse velocity or dynamic modulus of elasticity by using temperature. (author)

Breakwater stability with damaged single layer armour units

NARCIS (Netherlands)

De Rover, R.; Verhagen, H.J.; Van den Berge, A.; Reedijk, B.

2008-01-01

The effect of single layer interlocking armour unit breakage on the hydraulic armour layer stability and potential damage progression is addressed in this paper. A 2-dimensional scale model of a rubble mound breakwater with an armour layer consisting of Xbloc armour units was tested. The residual

Construction and building of a compact RFQ spiral structure for the stopping of highly charged heavy ion beams for the HITRAP project of the GSI

International Nuclear Information System (INIS)

Hofmann, B.

2007-01-01

For experiments of the atomic-physics group of the GSI in Darmstadt an ion stopper is built, which will make low-energetic, extremely highly charged ions available. The plannings for the so-called HITRAP (highly charged ion's trap) began at the beginning of the ninetieth. With this facility highly-charged heavy ions shall be stopped in two stages to very low, thermal velocities, and be available for highly precise mass spectroscopy, measurements of the g factor of the bound electron of hydrogen-like ions, and other atomic-physics experiments. This decelerator facility shall first be built in the reinjection channel behind the ESR with the possibility, to apply all components later in teh extension of the GSI in the framework of the FAIR project in the facility for low-energetic antiprotons and ions to be newly built. the present thesis treats the development and the building of an integrated RFQ debuncher stopping accelerator, which represents a part of the HITRAP stopping structures. By this the ion beam is stopped from the IH stopping accelerator with an energy of 500 keV/u to 5 keV/u. By the integrated spiral buncher the beam can be fitted in energy and energy deviation to the subsequent cooler trap. In this thesis the foundations of the particle dynamics in a RFQ accelerator for the stopping of particle beams were worked out and realized, the particle-dynamics calculations necessary for the lay-out of such a structure performed with RFQSim, suitable RF structures with the simulation program Microwave Studio developed and studied, as well as the thermal load of the structures studied with the finite-element code ALGOR. A further, central topic of this thesis is the building and the tuning of the RFQ structure in order to reach a homogeneous as possible field distribution along the electrodes. Measurements of the fields in the RFQ were performed with a disturbing condenser, at the debuncher with a disturbing body. After successfully performed vacuum tests at the

Spectroscopic studies on the interaction and sonodynamic damage of neutral red (NR) to bovine serum albumin (BSA)

Energy Technology Data Exchange (ETDEWEB)

Liu Bin; Guo Ying [Department of Pharmacy, Liaoning University, Shenyang 110036 (China); Wang, Jun, E-mail: wangjun890@126.co [Department of Chemistry, Liaoning University, Shenyang 110036 (China); Xu Rui [Department of Chemistry, Liaoning University, Shenyang 110036 (China); Wang Xin; Wang Dan; Zhang Liqun [Department of Pharmacy, Liaoning University, Shenyang 110036 (China); Xu Yongnan [Department of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016 (China)

2010-06-15

In this paper, the interaction of neutral red (NR) with bovine serum albumin (BSA) and the sonodynamic damage to BSA under ultrasonic irradiation was studied by means of ultraviolet-visible (UV-vis) and fluorescence spectra. The quenching constant (K{sub SV}=5.749x10{sup 4} L/mol), binding constant (K{sub A}=3.19x10{sup 4} L/mol) and binding site number (n=0.9462) were measured. The binding distance (r=2.47 nm) between NR and BSA was obtained according to Foester's non-radiative energy transfer theory. The damage process of BSA molecules was detected by the hyperchromic effect of UV-vis spectra and quenching of intrinsic fluorescence spectra. In addition, the influencing factors such as ultrasonic irradiation time and NR concentration on the damage to BSA molecules were also considered. The results showed that the damage degree is enhanced with the increase of ultrasonic irradiation time and NR concentration. The possible mechanism of sonodynamic damage to BSA molecules was mainly mediated by singlet oxygen ({sup 1}O{sub 2}). Otherwise, the binding and damaging sites to BSA molecules were also estimated by synchronous fluorescence. The results indicated that the NR is more vicinal to tryptophan (Trp) residue than to tyrosine (Tyr) residue and the damage site is also mainly at Trp residues. The research result will bring a certain significance to use sonosensitive drugs in the fields of tumor treatment.

Self-Diagnosis of Damage in Carbon Fiber Reinforced Composites Using Electrical Residual Resistance Measurement

Energy Technology Data Exchange (ETDEWEB)

Kang, Ji Ho [KAERI, Daejeon (Korea, Republic of)

2009-08-15

The objective of this research was to develop a practical integrated approach using extracted features from electrical resistance measurements and coupled electromechanical models of damage, for in-situ damage detection and sensing in carbon fiber reinforced plastic(CFRP) composites. To achieve this objective, we introduced specific known damage (in terms of type, size, and location) into CFRP laminates and established quantitative relationships with the electrical resistance measurements. For processing of numerous measurement data, an autonomous data acquisition system was devised. We also established a specimen preparation procedure and a method for electrode setup. Coupon and panel CFRP laminate specimens with several known damage were tested. Coupon specimens with various sizes of artificial delaminations obtained by inserting Teflon film were manufactured and the resistance was measured. The measurement results showed that increase of delamination size led to increase of resistance implying that it is possible to sense the existence and size of delamination. A quasi-isotropic panel was manufactured and electrical resistance was measured. Then three different sizes of holes were drilled at a chosen location. The panel was prepared using the established procedures with six electrode connections on each side making a total of twenty-four electrodes. Vertical, horizontal, and diagonal pairs of electrodes were chosen and the resistance was measured. The measurement results showed the possibility of the established measurement system for an in-situ damage detection method for CFRP composite structures.

Optimum injection pressure of a cavitating jet on introduction of compressive residual stress into stainless steel

International Nuclear Information System (INIS)

Soyama, Hitoshi; Nagasaka, Kazuya; Takakuwa, Osamu; Naito, Akima

2011-01-01

In order to mitigate stress corrosion cracking of components used for nuclear power plants, introduction of compressive residual stress into sub-surface of the components is an effective maintenance method. The introduction of compressive residual stress using cavitation impact generated by injecting a high speed water jet into water was proposed. Water jet peening is now applying to reduce stress corrosion cracking of shrouds in the nuclear power plants. However, accidental troubles such as dropping off the components and cutting of the pipes by the jet occurred at the maintenance. In order to peen by the jet without damage, optimum injection pressure of the jet should be revealed. In the case of 'cavitation peening', cavitation is generated by injecting the high speed water jet into water. As working pressure at the cavitation peening is the pressure at cavitation bubble collapse, the injection pressure of the jet is not main parameter. The cavitation impact is increasing with the scale of the jet, i.e., scaling effect of the cavitation. It was revealed that the large scale jet at low injection pressure can introduce compressive residual stress into stainless steel comparing with the small scale jet at high injection pressure. As expected, a water jet at high injection pressure might make damage of the components. Namely, in order to avoid damage of the components, the jet at the low injection pressure will be suit for the introduction of compressive residual stress. In the present paper, in order to make clear optimum injection pressure of the cavitating jet for the introduction of compressive residual stress without damage, the residual stress of stainless steel treated by the jet at various injection pressure was measured by using an X-ray diffraction method. The injection pressure of the jet p 1 was varied from 5 MPa to 300 MPa. The diameter of the nozzle throat of the jet d was varied from 0.35 mm to 2.0 mm. The residual stress changing with depth was

Effect of electrical discharge machining on surface characteristics and machining damage of AISI D2 tool steel

International Nuclear Information System (INIS)

Guu, Y.H.; Hocheng, H.; Chou, C.Y.; Deng, C.S.

2003-01-01

In this work the electrical discharge machining (EDM) of AISI D2 tool steel was investigated. The surface characteristics and machining damage caused by EDM were studied in terms of machining parameters. Based on the experimental data, an empirical model of the tool steel was also proposed. A new damage variable was used to study the EDM damage. The workpiece surface and re-solidified layers were examined by a scanning electron microscopy. Surface roughness was determined with a surface profilometer. The residual stress acting on the EDM specimen was measured by the X-ray diffraction technique. Experimental results indicate that the thickness of the recast layer, and surface roughness are proportional to the power input. The EDM process introduces tensile residual stress on the machined surface. The EDM damage leads to strength degradation

Putative photoacoustic damage in skin induced by pulsed ArF excimer laser

Energy Technology Data Exchange (ETDEWEB)

Watanabe, S.; Flotte, T.J.; McAuliffe, D.J.; Jacques, S.L.

1988-05-01

Argon-fluoride excimer laser ablation of guinea pig stratum corneum causes deeper tissue damage than expected for thermal or photochemical mechanisms, suggesting that photoacoustic waves have a role in tissue damage. Laser irradiation (193 nm, 14-ns pulse) at two different radiant exposures, 62 and 156 mJ/cm2 per pulse, was used to ablate the 15-microns-thick stratum corneum of the skin. Light and electron microscopy of immediate biopsies demonstrated damage to fibroblasts as deep as 88 and 220 microns, respectively, below the ablation site. These depths are far in excess of the optical penetration depth of 193-nm light (1/e depth = 1.5 micron). The damage is unlikely to be due to a photochemical mechanism because (a) the photons will not penetrate to these depths, (b) it is a long distance for toxic photoproducts to diffuse, and (c) damage is proportional to laser pulse intensity and not the total dose that accumulates in the residual tissue; therefore, reciprocity does not hold. Damage due to a thermal mechanism is not expected because there is not sufficient energy deposited in the tissue to cause significant heating at such depths. The damage is most likely due to a photoacoustic mechanism because (a) photoacoustic waves can propagate deep into tissue, (b) the depth of damage increases with increasing laser pulse intensity rather than with increasing total residual energy, and (c) the effects are immediate. These effects should be considered in the evaluation of short pulse, high peak power laser-tissue interactions.

Radioadaptive response. Efficient repair of radiation-induced DNA damage in adapted cells

International Nuclear Information System (INIS)

Ikushima, Takaji; Aritomi, Hisako; Morisita, Jun

1996-01-01

To verify the hypothesis that the induction of a novel, efficient repair mechanism for chromosomal DNA breaks may be involved in the radioadaptive response, the repair kinetics of DNA damage has been studied in cultured Chinese hamster V79 cells with single-cell gel electrophoresis. The cells were adapted by priming exposure with 5 cGy of γ-rays and 4-h incubation at 37C. There were no indication of any difference in the initial yields of DNA double-strand breaks induced by challenging doses from non-adapted cells and from adapted cells. The rejoining of DNA double-strand breaks was monitored over 120 min after the adapted cells were challenged with 5 or 1.5 Gy, doses at the same level to those used in the cytogenetical adaptive response. The rate of DNA damage repair in adapted cells was higher than that in non-adapted cells, and the residual damage was less in adapted cells than in non-adapted cells. These results indicate that the radioadaptive response may result from the induction of a novel, efficient DNA repair mechanism which leads to less residual damage, but not from the induction of protective functions that reduce the initial DNA damage

Application of x-ray residual stress measurement to products

International Nuclear Information System (INIS)

Goto, T.; Iwamura, T.

1975-01-01

The X-ray residual stress measuring method is the only nondestructive method for measuring residual stress in polycrystalline materials. It is capable of obtaining information not only on macroscopic stress but also microscopic stress. The authors are employing this method for the development of pre-service and in-service inspection methods and for the improvement of various manufacturing techniques. In this paper, the results of measurement of some products as examples of its application are described. The examples introduced concern the following: (1) Selection of optimum conditions in heat treatment and stress-relief treatment. (2) Residual stress produced by mechanical processes such as autofrettage and flow form. (3) Check of manufacturing processes of rotary shaft and welded parts. (4) Estimation of fatigue strength of shot-peened part. (5) Detection of fatigue damage of shot-peened part. (auth.)

Effect of Benfotiamine in Podocyte Damage Induced by Peritoneal Dialysis Fluid

OpenAIRE

M?ller-Krebs, Sandra; Nissle, Katharina; Tsobaneli, Julia; Zeier, Martin; Kihm, Lars Philipp; Kender, Zoltan; Fleming, Thomas; Nawroth, Peter Paul; Reiser, Jochen; Schwenger, Vedat

2015-01-01

Background: In peritoneal dialysis (PD), residual renal function (RRF) fundamentally contributes to improved quality of life and patient survival. High glucose and advanced glycation end-products (AGE) contribute locally to peritoneal and systemically to renal damage. Integrity of podocyte structure and function is of special importance to preserve RRF. Benfotiamine could counteract the glucose and AGE-mediated toxicity by blocking hyperglycemia-associated podocyte damage via the pentose-phos...

Residual fatigue life evaluation of rail at squats seeds using 3D explicit finite element analysis

NARCIS (Netherlands)

Deng, X.; Naeimi, M.; Li, Z.; Qian, Z.

2014-01-01

A modeling procedure to predict the residual fatigue life of rail at squats seeds is developed in this article. Two models are involved: a 3D explicit Finite Element (FE) model to compute the stress and strain at squats in rail, and the J-S fatigue damage model to determine the residual fatigue life

Radiation hardness of superconducting magnet insulation materials for FAIR

International Nuclear Information System (INIS)

Seidl, Tim

2013-03-01

This thesis focuses on radiation degradation studies of polyimide, polyepoxy/glass-fiber composites and other technical components used, for example, in the superconducting magnets of new ion accelerators such as the planned International Facility for Antiproton and Ion Research (FAIR) at the GSI Helmholtz Center of Heavy Ion Research (GSI) in Darmstadt. As accelerators are becoming more powerful, i.e., providing larger energies and beam intensities, the potential risk of radiation damage to the components increases. Reliable data of the radiation hardness of accelerator materials and components concerning electrical, thermal and other technical relevant properties are of great interest also for other facilities such as the Large Hadron Collider (LHC) of CERN. Dependent on the position of the different components, induced radiation due to beam losses consists of a cocktail of gammas, neutrons, protons, and heavier particles. Although the number of heavy fragments of the initial projectiles is small compared to neutrons, protons, or light fragments (e.g. ? particles), their large energy deposition can induce extensive damage at rather low fluences (dose calculations show that the contribution of heavy ions to the total accumulated dose can reach 80 %). For this reason, defined radiation experiments were conducted using different energetic ion beams (from protons to uranium) and gamma radiation from a Co-60 source. The induced changes were analyzed by means of in-situ and ex-situ analytical methods, e.g. ultraviolet-visible and infrared spectroscopy, residual gas analysis, thermal gravimetric analysis, dielectric strength measurements, measurements of low temperature thermal properties, and performance tests. In all cases, the radiation induces a change in molecular structure as well as loss of functional material properties. The amount of radiation damage is found to be sensitive to the used type of ionizing radiation and the long term stability of the materials is

Modelling of creep damage development in ferritic steels

Energy Technology Data Exchange (ETDEWEB)

Sandstroem, R [Swedish Institute for Metals Research, Stockholm (Sweden)

1999-12-31

The physical creep damage, which is observed in fossil-fired power plants, is mainly due to the formation of cavities and their interaction. It has previously been demonstrated that both the nucleation and growth of creep cavities can be described by power functions in strain for low alloy and 12 % CrMoV creep resistant steels. It possible to show that the physical creep damage is proportional to the product of the number of cavities and their area. Hence, the physical creep damage can also be expressed in terms of the creep strain. In the presentation this physical creep damage is connected to the empirical creep damage classes (1-5). A creep strain-time function, which is known to be applicable to low alloy and 12 % CrMoV creep resistant steels, is used to describe tertiary creep. With this creep strain - time model the residual lifetime can be predicted from the observed damage. For a given damage class the remaining life is directly proportional to the service time. An expression for the time to the next inspection is proposed. This expression is a function of fraction of the total allowed damage, which is consumed till the next inspection. (orig.) 10 refs.

Modelling of creep damage development in ferritic steels

Energy Technology Data Exchange (ETDEWEB)

Sandstroem, R. [Swedish Institute for Metals Research, Stockholm (Sweden)

1998-12-31

The physical creep damage, which is observed in fossil-fired power plants, is mainly due to the formation of cavities and their interaction. It has previously been demonstrated that both the nucleation and growth of creep cavities can be described by power functions in strain for low alloy and 12 % CrMoV creep resistant steels. It possible to show that the physical creep damage is proportional to the product of the number of cavities and their area. Hence, the physical creep damage can also be expressed in terms of the creep strain. In the presentation this physical creep damage is connected to the empirical creep damage classes (1-5). A creep strain-time function, which is known to be applicable to low alloy and 12 % CrMoV creep resistant steels, is used to describe tertiary creep. With this creep strain - time model the residual lifetime can be predicted from the observed damage. For a given damage class the remaining life is directly proportional to the service time. An expression for the time to the next inspection is proposed. This expression is a function of fraction of the total allowed damage, which is consumed till the next inspection. (orig.) 10 refs.

Evaluation of Crops Sensitivity to Atrazine Soil Residual

Directory of Open Access Journals (Sweden)

E Izadi

2012-02-01

Full Text Available Abstract In order to study the sensitivity of 9 crops to atrazine soil residual, two separate experiments were conducted in field and greenhouse conditions. First experiment was conducted in a field with treated soil by atrazine based on split plot and the results evaluated in greenhouse conditions. Treatments in the field experiment included two organic manure application rates (0 and 50 t/ha as main plots and 2 atrazine application rates (2 and 4 kg/ha atrazine a.i. as sob plots. After corn harvesting soil was sampled at 0-15 cm surface layer in each plots in 15 points, after mixing the samples. Wheat, barley, sugar beet, pea, lens and colza planted in pots at greenhouse. Second experiment conducted in greenhouse conditions for evaluation of atrazine soil residual in completely randomized design. Treatments included atrazine soil residual concentrations (0, 0.2, 0.5, 1, 5, 10 and 15 mg/kg soil and crops included wheat, barley, sugar beet, pea, lens, rape, bean and tomato. Results showed that atrazine residue had no effect on crops growth in field experiment treated with atrazine. It seems that atrazine residue in filed soil is lower that its damage threshold for crops or maybe for its fast removal in field than in control conditions. But in bioassay experiment (greenhouse experiment crops response to atrazine residues were different. Results showed that onion and pea were most susceptible ant tolerant crops between studied species and based of ED50 parameter the other crops tolerance to total residue ranked as: pea< bean< lentil< sugar beet< tomato< barley< wheat< rape< onion. Keywords: Atrazine residue, Pea, Bean, Lentil, Sugar beet, Barley, Wheat, Rape, Tomato

Spectrum Fatigue Lifetime and Residual Strength for Fiberglass Laminates; TOPICAL

International Nuclear Information System (INIS)

WAHL, NEIL K.; MANDELL, JOHN F.; SAMBORSKY, DANIEL D.

2002-01-01

This report addresses the effects of spectrum loading on lifetime and residual strength of a typical fiberglass laminate configuration used in wind turbine blade construction. Over 1100 tests have been run on laboratory specimens under a variety of load sequences. Repeated block loading at two or more load levels, either tensile-tensile, compressive-compressive, or reversing, as well as more random standard spectra have been studied. Data have been obtained for residual strength at various stages of the lifetime. Several lifetime prediction theories have been applied to the results. The repeated block loading data show lifetimes that are usually shorter than predicted by the most widely used linear damage accumulation theory, Miner's sum. Actual lifetimes are in the range of 10 to 20 percent of predicted lifetime in many cases. Linear and nonlinear residual strength models tend to fit the data better than Miner's sum, with the nonlinear providing a better fit of the two. Direct tests of residual strength at various fractions of the lifetime are consistent with the residual strength models. Load sequencing effects are found to be insignificant. The more a spectrum deviates from constant amplitude, the more sensitive predictions are to the damage law used. The nonlinear model provided improved correlation with test data for a modified standard wind turbine spectrum. When a single, relatively high load cycle was removed, all models provided similar, though somewhat non-conservative correlation with the experimental results. Predictions for the full spectrum, including tensile and compressive loads were slightly non-conservative relative to the experimental data, and accurately captured the trend with varying maximum load. The nonlinear residual strength based prediction with a power law S-N curve extrapolation provided the best fit to the data in most cases. The selection of the constant amplitude fatigue regression model becomes important at the lower stress, higher

Secondary ion emission from cleaned surfaces bombarded by 100 MeV accelerator beams at the GSI Darmstadt

International Nuclear Information System (INIS)

Wien, K.; Becker, O.; Guthier, W.; Knippelberg, W.; Koczon, P.

1988-01-01

The 1.4 MeV/n beam facility for the UNILAC/GSI has been used to study secondary ion emission from surfaces cleaned under UHV conditions by ion etching or cleaving of crystals. The desorption phenomena observed by means of TOF mass spectrometry can be classified as follows: (1) Clean metal surfaces emit metal ions being ejected by atomic collisions cascades. Electronic excitation of surface states seems to support ionization. (2) The desorption of contaminants adsorbed at the metal surface is strongly correlated with the electronic energy loss of the projectiles - even, if the content of impurities is very low. (3) Ion formation at the epitaxial surface of fluoride crystals as CaF 2 , MgF 2 and NaF is initiated by the electronic excitation of the crystal. At high beam energies the mass spectrum is dominated by a series of cluster ions. These cluster ions disappear below a certain energy deposit threshold, whereas small atomic ions are observed over the whole energy range

Sex-specific genetic effects in physical activity: results from a quantitative genetic analysis.

Science.gov (United States)

Diego, Vincent P; de Chaves, Raquel Nichele; Blangero, John; de Souza, Michele Caroline; Santos, Daniel; Gomes, Thayse Natacha; dos Santos, Fernanda Karina; Garganta, Rui; Katzmarzyk, Peter T; Maia, José A R

2015-08-01

The objective of this study is to present a model to estimate sex-specific genetic effects on physical activity (PA) levels and sedentary behaviour (SB) using three generation families. The sample consisted of 100 families covering three generations from Portugal. PA and SB were assessed via the International Physical Activity Questionnaire short form (IPAQ-SF). Sex-specific effects were assessed by genotype-by-sex interaction (GSI) models and sex-specific heritabilities. GSI effects and heterogeneity were tested in the residual environmental variance. SPSS 17 and SOLAR v. 4.1 were used in all computations. The genetic component for PA and SB domains varied from low to moderate (11% to 46%), when analyzing both genders combined. We found GSI effects for vigorous PA (p = 0.02) and time spent watching television (WT) (p < 0.001) that showed significantly higher additive genetic variance estimates in males. The heterogeneity in the residual environmental variance was significant for moderate PA (p = 0.02), vigorous PA (p = 0.006) and total PA (p = 0.001). Sex-specific heritability estimates were significantly higher in males only for WT, with a male-to-female difference in heritability of 42.5 (95% confidence interval: 6.4, 70.4). Low to moderate genetic effects on PA and SB traits were found. Results from the GSI model show that there are sex-specific effects in two phenotypes, VPA and WT with a stronger genetic influence in males.

Nondestructive indication of fatigue damage and residual lifetime in ferromagnetic construction materials

Czech Academy of Sciences Publication Activity Database

Tomáš, Ivan; Kovářík, O.; Vértesy, G.; Kadlecová, Jana

2014-01-01

Roč. 25, č. 6 (2014), "065601-1"-"065601-10" ISSN 0957-0233. [International Symposium on Measurement Technology and Intelligent Instruments /11./ (ISMTII). Aachen, 01.07.2013-03.07.2013] R&D Projects: GA ČR(CZ) GAP108/12/1872 Institutional support: RVO:68378271 Keywords : fatigue * residual lifetime * magnetic nondestructive evaluation * ferromagnetic construction materials Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.433, year: 2014

A damage mechanics based approach to structural deterioration and reliability

Energy Technology Data Exchange (ETDEWEB)

Bhattcharya, B.; Ellingwood, B. [Johns Hopkins Univ., Baltimore, MD (United States). Dept. of Civil Engineering

1998-02-01

Structural deterioration often occurs without perceptible manifestation. Continuum damage mechanics defines structural damage in terms of the material microstructure, and relates the damage variable to the macroscopic strength or stiffness of the structure. This enables one to predict the state of damage prior to the initiation of a macroscopic flaw, and allows one to estimate residual strength/service life of an existing structure. The accumulation of damage is a dissipative process that is governed by the laws of thermodynamics. Partial differential equations for damage growth in terms of the Helmholtz free energy are derived from fundamental thermodynamical conditions. Closed-form solutions to the equations are obtained under uniaxial loading for ductile deformation damage as a function of plastic strain, for creep damage as a function of time, and for fatigue damage as function of number of cycles. The proposed damage growth model is extended into the stochastic domain by considering fluctuations in the free energy, and closed-form solutions of the resulting stochastic differential equation are obtained in each of the three cases mentioned above. A reliability analysis of a ring-stiffened cylindrical steel shell subjected to corrosion, accidental pressure, and temperature is performed.

A damage mechanics based approach to structural deterioration and reliability

International Nuclear Information System (INIS)

Bhattcharya, B.; Ellingwood, B.

1998-02-01

Structural deterioration often occurs without perceptible manifestation. Continuum damage mechanics defines structural damage in terms of the material microstructure, and relates the damage variable to the macroscopic strength or stiffness of the structure. This enables one to predict the state of damage prior to the initiation of a macroscopic flaw, and allows one to estimate residual strength/service life of an existing structure. The accumulation of damage is a dissipative process that is governed by the laws of thermodynamics. Partial differential equations for damage growth in terms of the Helmholtz free energy are derived from fundamental thermodynamical conditions. Closed-form solutions to the equations are obtained under uniaxial loading for ductile deformation damage as a function of plastic strain, for creep damage as a function of time, and for fatigue damage as function of number of cycles. The proposed damage growth model is extended into the stochastic domain by considering fluctuations in the free energy, and closed-form solutions of the resulting stochastic differential equation are obtained in each of the three cases mentioned above. A reliability analysis of a ring-stiffened cylindrical steel shell subjected to corrosion, accidental pressure, and temperature is performed

Damage tolerance of candidate thermoset composites for use on single stage to orbit vehicles

Science.gov (United States)

Nettles, A. T.; Lance, D.; Hodge, A.

1994-01-01

Four fiber/resin systems were compared for resistance to damage and damage tolerance. One toughened epoxy and three toughened bismaleimide (BMI) resins were used, all with IM7 carbon fiber reinforcement. A statistical design of experiments technique was used to evaluate the effects of impact energy, specimen thickness, and impactor diameter on the damage area, as computed by C-scans, and residual compression-after-impact (CAI) strength. Results showed that two of the BMI systems sustained relatively large damage zones yet had an excellent retention of CAI strength.

Damages to soil and tree species by cable-skidding in Caspian forests of Iran

Energy Technology Data Exchange (ETDEWEB)

Tavankar, Farzam; Bonyad, Amir E.; Nikooy, Mehrdad; Picchio, Rodolfo; Venanzi, Rachele; Calienno, Luca

2017-11-01

Aim of study: The main aims of this study were to determine of damage level to residual stand and soil disturbance from mechanized selection logging. Area of study: Mixed beech stands in Caspian forests, northern Iran. Material and methods: Point-transect and systematic plot sampling were used for assessing damages to soil and trees, respectively. Main results: 89% of forest soil area was undisturbed or shallow disturbed, and 5.2% was deep disturbed. Soil bulk density of top 10 cm in the winching corridors, ruts and skid trails were increased 10.7%, 20.6% and 32.1% respectively than controlled area. Frequency of damages to regeneration and trees were 12% and 11.2%. The frequency of damages to regeneration was increased with increasing of their heights, but frequency of damages to trees was decreased with increasing of their diameter. The most type of damages was bole wounds in sizes of 100 to 200 cm2 within 1 m from the ground level, and deep wounds. The frequency of damages was different in tree species (p = 0.001). The mean size of bole wounds was 174 cm2, and the mean height of bole wounds was 70 cm from ground level. The intensity of wounds on trees bole were decreased with increasing of their heights from ground level (p = 0.02), while their sizes were increased (p = 0.001). Research highlights: Winching of logs was the main cause of damages to soil and residual stand. The detailed planning strategy will reduce damage to level which is acceptable and predictable.

Damages to soil and tree species by cable-skidding in Caspian forests of Iran

International Nuclear Information System (INIS)

Tavankar, Farzam; Bonyad, Amir E.; Nikooy, Mehrdad; Picchio, Rodolfo; Venanzi, Rachele; Calienno, Luca

2017-01-01

Aim of study: The main aims of this study were to determine of damage level to residual stand and soil disturbance from mechanized selection logging. Area of study: Mixed beech stands in Caspian forests, northern Iran. Material and methods: Point-transect and systematic plot sampling were used for assessing damages to soil and trees, respectively. Main results: 89% of forest soil area was undisturbed or shallow disturbed, and 5.2% was deep disturbed. Soil bulk density of top 10 cm in the winching corridors, ruts and skid trails were increased 10.7%, 20.6% and 32.1% respectively than controlled area. Frequency of damages to regeneration and trees were 12% and 11.2%. The frequency of damages to regeneration was increased with increasing of their heights, but frequency of damages to trees was decreased with increasing of their diameter. The most type of damages was bole wounds in sizes of 100 to 200 cm2 within 1 m from the ground level, and deep wounds. The frequency of damages was different in tree species (p = 0.001). The mean size of bole wounds was 174 cm2, and the mean height of bole wounds was 70 cm from ground level. The intensity of wounds on trees bole were decreased with increasing of their heights from ground level (p = 0.02), while their sizes were increased (p = 0.001). Research highlights: Winching of logs was the main cause of damages to soil and residual stand. The detailed planning strategy will reduce damage to level which is acceptable and predictable.

Detection of mechanical damage using the magnetic flux leakage technique

International Nuclear Information System (INIS)

Clapham, L.; Babbar, V.; Byrne, J.

2007-01-01

Since magnetism is strongly stress dependent, Magnetic Flux Leakage (MFL) inspection tools have the potential to locate and characterize mechanical damage in pipelines. However, MFL application to mechanical damage detection faces hurdles which make signal interpretation problematic: 1) the MFL signal is a superposition of geometrical and stress effects; 2) the stress distribution around a mechanically damaged region is very complex, consisting of plastic deformation and residual (elastic) stresses; 3) the effect of stress on magnetic behaviour is not well understood. This paper summarizes recent results of experimental and modeling studies of MFL signals resulting from mechanical damage. In experimental studies, mechanical damage was simulated using a tool and die press to produce dents of varying depths in plate samples. MFL measurements were made before and after selective stress-relieving heat treatments. These annealing treatments enabled the stress and geometry components of the MFL signal to be separated. In general, geometry effects scale with dent depth and tend to dominate in deep dents, while stress contribution to the MFL signals is relatively constant and is more significant for shallow dents. The influence of other parameters such as flux density and topside/bottomside inspection was also quantified. In the finite element analysis work, stress was incorporated by modifying the magnetic permeability in the residual stress regions of the modeled dent. Both stress and geometry contributions to the MFL signal were examined separately. Despite using a number of simplifying assumptions, the modeled results matched the experimental results very closely, and were used to aid in interpretation of the MFL signals. (author)

$\\beta$-decay and $\\beta$-delayed Neutron Emission Measurements at GSI-FRS Beyond N=126, for r-process Nucleosynthesis

CERN Document Server

Caballero-Folch, R; Cortès, G; Taín, J L; Agramunt, J; Algora, A; Ameil, F; Ayyad, Y; Benlliure, J; Bowry, M; Calviño, F; Cano-Ott, D; Davinson, T; Dillmann, I; Estrade, A; Evdokimov, A; Faestermann, T; Farinon, F; Galaviz, D; García-Ríos, A; Geissel, H; Gelletly, W; Gernhäuser, R; Gómez-Hornillos, M B; Guerrero, C; Heil, M; Hinke, C; Knöbel, R; Kojouharov, I; Kurcewicz, J; Kurz, N; Litvinov, Y; Maier, L; Marganiec, J; Marta, M; Martínez, T; Montes, F; Mukha, I; Napoli, D R; Nociforo, C; Paradela, C; Pietri, S; Podolyák, Zs; Prochazka, A; Rice, S; Riego, A; Rubio, B; Schaffner, H; Scheidenberger, C; Smith, K; Sokol, E; Steiger, K; Sun, B; Takechi, M; Testov, D; Weick, H; Wilson, E; Winfield, J S; Wood, R; Woods, P J; Yeremin, A

2014-01-01

New measurements of very exotic nuclei in the neutron-rich region beyond N=126 have been performed at the GSI facility with the fragment separator (FRS). The aim of the experiment is to determine half-lives and beta-delayed neutron emission branching ratios of isotopes of Hg, Tl and Pb in this region. This contribution summarizes final counting statistics for identification and for implantation, as well as the present status of the data analysis of the half-lives. In summary, isotopes of Pt, Au, Hg, Ti, Pb, Bi, Po, At, Rn and Fr were clearly identified and several of them (Hg208-211, Tl211-215, Pb214-218) were implanted with enough statistics to determine their half-lives. About half of them are expected to be neutron emitters, in such cases it will become possible to obtain the neutron emission probabilities, P-n.

Energy dependence of isotopic spectra from spallation residues; Dependance en energie des spectres isotopiques de residus de spallation

Energy Technology Data Exchange (ETDEWEB)

Audouin, L

2003-09-01

Spallation reactions are collisions between heavy nuclei and light particle with an energy of a few hundreds MeV. The y are considered as a suitable way to create high- flux neutrons sources, which may used for example for the transmutation of nuclear wastes (hybrid reactors). The study of the residues from such reactions is both a way to understand the physics of the spallation and to provide information required for the design of industrial targets. The residues from the spallation of lead by proton at 500 MeV have been measured using the inverse kinematics technique in the FRS (fragments recoil separator). spectrometer from GSI (Barmstadt). This low energy required the use of new technique, for the experimental setup as well as during the analysis. The fragments were identified in-flight, prior to {beta} decay. Complete isotopic distributions are obtained with an accuracy ranging between 10 and 30%. Detailed information on the reaction kinematics are also obtained. Data are in excellent agreement with radio-chemical measurements, and bring new insights about the spallation process. The comparison with data measured on the same system with an incident energy of 1 GeV allows to discuss the influence of the projectile energy on the residues formation. It is concluded that the independence of the shape of the isobaric production cross sections regarding mass and energy of the projectile is preserved at low incident energies. The behaviour of Monte-Carlo codes is discussed with respect to those sets of data. The calculations show an improving agreement with decreasing energy, indicating that high-energy phenomena, for which some common assumptions become questionable, are the main reason for the observed discrepancies. (author)

Evaluation of creep damage due to stress relaxation in SA533 grade B class 1 and SA508 class 3 pressure vessel steels

International Nuclear Information System (INIS)

Hoffmann, C.L.; Urko, W.

1993-01-01

Creep damage can result from stress relaxation of residual stresses in components when exposed to high temperature thermal cycles. Pressure vessels, such as the reactor vessel of the modular high-temperature gas reactor (MHTGR), which normally operate at temperatures well below the creep range can develop relatively high residual stresses in high stress locations. During short term excursions to elevated-temperatures, creep damage can be produced by the loadings on the vessel. In addition, residual stresses will relax out, causing greater creep damage in the pressure vessel material than might otherwise be calculated. The evaluation described in this paper assesses the magnitude of the creep damage due to relaxation of residual stresses resulting from short term exposure of the pressure vessel material to temperatures in the creep range. Creep relaxation curves were generated for SA533 Grade B, Class 1 and SA508 Class 3 pressure vessel steels using finite element analysis of a simple uniaxial truss loaded under constant strain conditions to produce an initial axial stress equal to 1.25 times the material yield strength at temperature. The strain is held constant for 1000 hours at prescribed temperatures from 700 F to 1000 F. The material creep law is used to calculate the relaxed stress for each time increment. The calculated stress relaxation versus time curves are compared with stress relaxation test data. Creep damage fractions are calculated by integrating the stress relaxation versus time curves and performing a linear creep damage summation using the minimum stress to rupture curves at the respective relaxation temperatures. Cumulative creep damage due to stress relaxation as a function of time and temperature is derived from the linear damage summation

Residual Strains and Their Relation to the Fatigue Damage Evolution in Composite Materials

DEFF Research Database (Denmark)

Mikkelsen, Lars Pilgaard; Pereira, Gilmar Ferreira; Jespersen, Kristine Munk

2016-01-01

, the volumetric shrinkage of the epoxy at the two curing cycles is identical, the resulting residual strain in an embedded optical fibre measured using fibre Bragg Grating is found to be increased with a factor of 3. Together with, 3D x-ray tomography of partly fatigued test specimens there is an indication...

Concepts for improving the damage tolerance of composite compression panels. [aircraft structures

Science.gov (United States)

Rhodes, M. D.; Williams, J. G.

1984-01-01

The residual strength of specimens with damage and the sensitivity to damage while subjected to an applied inplane compression load were determined for flatplate specimens and blade-stiffened panels. The results suggest that matrix materials that fail by delamination have the lowest damage tolerance capability. Alternate matrix materials or laminates which are transversely reinforced suppress the delamination mode of failure and change the failure mode to transverse shear crippling which occurs at a higher strain value. Several damage-tolerant blade-stiffened panel design concepts are evaluated. Structural efficiency studies conducted show only small mass penalties may result from incorporating these damage-tolerant features in panel design. The implication of test results on the design of aircraft structures was examined with respect to FAR requirements.

Self-Healing Characteristics of Damaged Rock Salt under Different Healing Conditions

Directory of Open Access Journals (Sweden)

Lin Li

2013-08-01

Full Text Available Salt deposits are commonly regarded as ideal hosts for geologic energy reservoirs. Underground cavern construction-induced damage in salt is reduced by self-healing. Thus, studying the influencing factors on such healing processes is important. This research uses ultrasonic technology to monitor the longitudinal wave velocity variations of stress-damaged rock salts during self-recovery experiments under different recovery conditions. The influences of stress-induced initial damage, temperature, humidity, and oil on the self-recovery of damaged rock salts are analyzed. The wave velocity values of the damaged rock salts increase rapidly during the first 200 h of recovery, and the values gradually increase toward stabilization after 600 h. The recovery of damaged rock salts is subjected to higher initial damage stress. Water is important in damage recovery. The increase in temperature improves damage recovery when water is abundant, but hinders recovery when water evaporates. The presence of residual hydraulic oil blocks the inter-granular role of water and restrains the recovery under triaxial compression. The results indicate that rock salt damage recovery is related to the damage degree, pore pressure, temperature, humidity, and presence of oil due to the sealing integrity of the jacket material.

Quantification of residual stress from photonic signatures of fused silica

International Nuclear Information System (INIS)

Cramer, K. Elliott; Yost, William T.; Hayward, Maurice

2014-01-01

A commercially available grey-field polariscope (GFP) instrument for photoelastic examination is used to assess impact damage inflicted upon the outer-most pane of Space Shuttle windows made from fused silica. A method and apparatus for calibration of the stress-optic coefficient using four-point bending is discussed. The results are validated on known material (acrylic) and are found to agree with literature values to within 6%. The calibration procedure is then applied to fused-silica specimens and the stress-optic coefficient is determined to be 2.43 ± 0.54 × 10 −12 Pa −1 . Fused silica specimens containing impacts artificially made at NASA’s Hypervelocity Impact Technology Facility (HIT-F), to simulate damage typical during space flight, are examined. The damage sites are cored from fused silica window carcasses and examined with the GFP. The calibrated GFP measurements of residual stress patterns surrounding the damage sites are presented

Effect of Post-Fire Curing on the Residual Mechanical Properties of Fire-Damaged Self-Compacting Concrete

NARCIS (Netherlands)

Mirmomeni, M.; Heidarpour, A.; Schlangen, H.E.J.G.; Smith, S; Saouma, V.; Bolander, J.; Landis, E.

2016-01-01

Concrete is recognized for being a fire-resistant construction material. At elevated temperatures concrete can, however, undergo considerable damage such as strength degradation, cracking, and explosive spalling. In recent decades, reuse of fire-damaged concrete structures by means of developing

Residual life estimation of cracked aircraft structural components

OpenAIRE

Maksimović, Mirko S.; Vasović, Ivana V.; Maksimović, Katarina S.; Trišović, Nataša; Maksimović, Stevan M.

2018-01-01

The subject of this investigation is focused on developing computation procedure for strength analysis of damaged aircraft structural components with respect to fatigue and fracture mechanics. For that purpose, here will be defined computation procedures for residual life estimation of aircraft structural components such as wing skin and attachment lugs under cyclic loads of constant amplitude and load spectrum. A special aspect of this investigation is based on using of the Strain Energy Den...

Stress-Softening and Residual Strain Effects in Suture Materials

Directory of Open Access Journals (Sweden)

Alex Elías-Zúñiga

2013-01-01

Full Text Available This work focuses on the experimental characterization of suture material samples of MonoPlus, Monosyn, polyglycolic acid, polydioxanone 2–0, polydioxanone 4–0, poly(glycolide-co-epsilon-caprolactone, nylon, and polypropylene when subjected to cyclic loading and unloading conditions. It is found that all tested suture materials exhibit stress-softening and residual strain effects related to the microstructural material damage upon deformation from the natural, undistorted state of the virgin suture material. To predict experimental observations, a new constitutive material model that takes into account stress-softening and residual strain effects is developed. The basis of this model is the inclusion of a phenomenological nonmonotonous softening function that depends on the strain intensity between loading and unloading cycles. The theory is illustrated by modifying the non-Gaussian average-stretch, full-network model to capture stress-softening and residual strains by using pseudoelasticity concepts. It is shown that results obtained from theoretical simulations compare well with suture material experimental data.

Neutron dose measurements with the GSI ball at high energy accelerators

International Nuclear Information System (INIS)

Fehrenbacher, G.; Gutermuth, F.; Radon, T.; Kozlova, E.

2005-01-01

Full text: At high energy particle accelerators the production of neutron radiation dominates radiation protection. For the radiation survey at accelerators there is a need for reliable detection systems (passive radiation monitors), which can measure the dose for a wide range of neutron energies independently on the beam pulse structure of the produced radiation. In this work a passive neutron dosemeter for the measurement of the ambient dose equivalent is presented. The dosemeter is suitable for measurements of the emerging neutron radiation at accelerators for the whole energy range up to about 10 GeV. The dosemeter consists of a polyethylene sphere, TL elements (pairs of TLD600/700) and an additional lead layer (PE/Pb) in neutron fields at high energy accelerators is investigated in this work. Results of dose measurements which were performed in realistic neutron fields at the high energy accelerator SPS at CERN (CERF facility) and in Cave A at the heavy ion synchrotron SIS at GSI are presented. The results of these measurements are compared with the expected dose values from the neutron spectra determined for the measurement positions at CERF and in Cave A (FLUKA) and with the dosemeter response derived by the calculated response functions (FLUKA) folded with the neutron spectra. The comparisons show that the additional lead layer in the PE/Pb-sphere improves significantly the response of the dosemeter. The response of the PE/Pb-sphere is 40 to 50 % higher at CERF and Cave A in comparison to the bare PE-sphere. At CERF the dose values of the PE/Pb-sphere is about 25 % lower than the expected dose value, whilst for Cave A, a rather good agreement was found (2 % deviation). (author)

Spectroscopic analyses on interaction of bovine serum albumin (BSA) with toluidine blue (TB) and its sonodynamic damage under ultrasonic irradiation

Energy Technology Data Exchange (ETDEWEB)

Wang Jun, E-mail: wangjun890@126.co [Department of Chemistry, Liaoning University, Shenyang 110036 (China); Guo Yuwei [Department of Chemistry, Liaoning University, Shenyang 110036 (China); Department of Chemistry, Baotou Normal College, Baotou 014030 (China); Liu Bin [Department of Pharmacy, Liaoning University, Shenyang 110036 (China); Cheng Chunping [Department of Chemistry, Baotou Normal College, Baotou 014030 (China); Wang Zhiqiu; Han Guangxi; Gao Jingqun; Zhang Xiangdong [Department of Chemistry, Liaoning University, Shenyang 110036 (China)

2011-02-15

In this paper, the toluidine blue (TB) with tricyclic quinone imide plane structure is used as sonosensitizer to study the interaction and sonodynamic damage to bovine serum albumin (BSA) by UV-vis and fluorescence spectroscopy. The results show that the TB can bind to BSA molecules, obviously, and the synergetic effects of TB and ultrasonic irradiation can efficiently damage the BSA molecules. Otherwise, some influencing factors such as ultrasonic irradiation time, TB concentration, pH value and ionic strength on the damage of BSA molecules were also considered by the numbers. Synchronous fluorescence spectroscopy indicates that the tyrosine (Tyr) residues of BSA molecules are damaged more seriously than the tryptophan (Trp) residues under ultrasonic irradiation. - Research Highlights: TB is used as quencher to study interaction to BSA. TB is used as sonosensitizer to study the sonodynamic damage to BSA. Synchronous fluorescence spectroscopy is used to study TB binding site to BSA.

Long term subsidence movements and behavior of subsidence-damaged structures

International Nuclear Information System (INIS)

Mahar, J.W.; Marino, G.G.

1999-01-01

Surface ground movement related to sag mine subsidence has been monitored above Illinois abandoned room and pillar coal workings for periods of more than 15 years. The long term movement related to a specific mine subsidence is typically small relative to the initial displacements but have caused crack and tilt damage in both repaired and unrepaired structures. Seasonal variations in ground surface elevations are superimposed on the downward movement related to mine subsidence. Thus it is necessary to measure long term subsidence movement at about the same time each year in order to minimize environmental factors. This paper presents long term monitoring data from five subsidence sags in central and southern Illinois. The abandoned coal mine workings are located at depths of 160 to 460 ft below the ground surface. measured residual mine subsidence ranges between 1.4 and 3.6 in. 4.4 to 15 years after mine failure. The magnitude of downward displacement is greater than settlement design values (1 in.) and are at rates (0.0004 to 0.0056 ft/month) that cause damage to structures. Most of the damage in unrepaired structures occurs along existing cracks and separations. In all five cases, the ground movements are continuing at residual rates. Sag subsidence movement in Illinois takes place for a minimum of five years after the damage is manifested at the ground surface. A classification of say development is provided based on the displacement-time data

Residual nilpotence and residual solubility of groups

International Nuclear Information System (INIS)

Mikhailov, R V

2005-01-01

The properties of the residual nilpotence and the residual solubility of groups are studied. The main objects under investigation are the class of residually nilpotent groups such that each central extension of these groups is also residually nilpotent and the class of residually soluble groups such that each Abelian extension of these groups is residually soluble. Various examples of groups not belonging to these classes are constructed by homological methods and methods of the theory of modules over group rings. Several applications of the theory under consideration are presented and problems concerning the residual nilpotence of one-relator groups are considered.

Effects of relative density and accumulated shear strain on post-liquefaction residual deformation

Directory of Open Access Journals (Sweden)

J. Kim

2013-10-01

Full Text Available The damage caused by liquefaction, which occurs following an earthquake, is usually because of settlement and lateral spreading. Generally, the evaluation of liquefaction has been centered on settlement, that is, residual volumetric strain. However, in actual soil, residual shear and residual volumetric deformations occur simultaneously after an earthquake. Therefore, the simultaneous evaluation of the two phenomena and the clarification of their relationship are likely to evaluate post-liquefaction soil behaviors more accurately. Hence, a quantitative evaluation of post-liquefaction damage will also be possible. In this study, the effects of relative density and accumulated shear strain on post-liquefaction residual deformations were reviewed through a series of lateral constrained-control hollow cylindrical torsion tests under undrained conditions. In order to identify the relationship between residual shear and residual volumetric strains, this study proposed a new test method that integrates monotonic loading after cyclic loading, and K0-drain after cyclic loading – in other words, the combination of cyclic loading, monotonic loading, and the K0 drain. In addition, a control that maintained the lateral constrained condition across all the processes of consolidation, cyclic loading, monotonic loading, and drainage was used to reproduce the anisotropy of in situ ground. This lateral constrain control was performed by controlling the axial strain, based on the assumption that under undrained conditions, axial and lateral strains occur simultaneously, and unless axial strain occurs, lateral strain does not occur. The test results confirmed that the recovery of effective stresses, which occur during monotonic loading and drainage after cyclic loading, respectively, result from mutually different structural restoration characteristics. In addition, in the ranges of 40–60% relative density and 50–100% accumulated shear strain, relative

Residual Strength Pressure Tests and Nonlinear Analyses of Stringer- and Frame-Stiffened Aluminum Fuselage Panels with Longitudinal Cracks

Science.gov (United States)

Young, Richard D.; Rouse, Marshall; Ambur, Damodar R.; Starnes, James H., Jr.

1999-01-01

The results of residual strength pressure tests and nonlinear analyses of stringer- and frame-stiffened aluminum fuselage panels with longitudinal cracks are presented. Two types of damage are considered: a longitudinal crack located midway between stringers, and a longitudinal crack adjacent to a stringer and along a row of fasteners in a lap joint that has multiple-site damage (MSD). In both cases, the longitudinal crack is centered on a severed frame. The panels are subjected to internal pressure plus axial tension loads. The axial tension loads are equivalent to a bulkhead pressure load. Nonlinear elastic-plastic residual strength analyses of the fuselage panels are conducted using a finite element program and the crack-tip-opening-angle (CTOA) fracture criterion. Predicted crack growth and residual strength results from nonlinear analyses of the stiffened fuselage panels are compared with experimental measurements and observations. Both the test and analysis results indicate that the presence of MSD affects crack growth stability and reduces the residual strength of stiffened fuselage shells with long cracks.

Imaging subsurface damage of grinded fused silica optics by confocal fluorescence microscopy

International Nuclear Information System (INIS)

Neauport, J.; Cormont, P.; Destribats, J.; Legros, P.; Ambard, C.

2009-01-01

We report an experimental investigation of fluorescence confocal microscopy as a tool to measure subsurface damage on grinded fused silica optics. Confocal fluorescence microscopy was performed with an excitation at the wavelength of 405 nm on fixed abrasive diamond grinded fused silica samples. We detail the measured fluorescence spectrums and compare them to those of oil based coolants and grinding slurries. We evidence that oil based coolant used in diamond grinding induces a fluorescence that marks the subsurface damages and eases its observation. Such residual traces might also be involved in the laser damage process. (authors)

A new matcher type between RFQ and IH-DTL for the GSI high current heavy ion prestripper linac

International Nuclear Information System (INIS)

Ratzinger, U.; Tiede, R.

1996-01-01

The adaptation of a RFQ beam to the typical requirements at the entrance of a drift tube linac is rather difficult at high intensities and high A/q values. The high focusing power needed for such a matcher can be provided by a conventional array with rather large quadrupoles and rebuncher cavities only. Many problems arising from such a design can be avoided by using an element which is focusing in transverse and longitudinal direction at the same time, that is a short RFQ ('Super Lens') with 10 cells typically and a larger aperture as compared to the main RFQ. A xy-steerer and a short quadrupole doublet with small aperture were added to gain flexibility with regard to beam mismatch and misalignment corrections. This new concept is realised for the GSI 15 mA U 4+ injector, which is under construction. Beam dynamics calculations are presented and compared with results for a conventional solution consisting of a rebuncher and a quadrupole triplet. (author)

Plant Residual Management in different Crop Rotations System on Potato Tuber Yield Loss Affected by Wireworms

Directory of Open Access Journals (Sweden)

A. Zarea Feizabadi

2016-07-01

Full Text Available Introduction: Selection a proper crop rotation based on environmental conservation rules is a key factor for increasing long term productivity. On the other hand, the major problem in reaching agricultural sustainability is lack of soil organic matter. Recently, a new viewpoint has emerged based on efficient use of inputs, environmental protection, ecological economy, food supply and security. Crop rotation cannot supply and restore plant needed nutrients, so gradually the productivity of rotation system tends to be decreased. Returning the plant residues to the soil helps to increase its organic matter and fertility in long-term period. Wireworms are multi host pests and we can see them in wheat and barley too. The logic way for their control is agronomic practices like as crop rotation. Wireworms’ population and damages are increased with using grasses and small seed gramineas in mild winters, variation in cropping pattern, reduced chemical control, and cover crops in winter. In return soil cultivation, crop rotation, planting date, fertilizing, irrigation and field health are the examples for the effective factors in reducing wireworms’ damage. Materials and Methods: In order to study the effect of crop rotations, residue management and yield damage because of wireworms’ population in soil, this experiment was conducted using four rotation systems for five years in Jolgeh- Rokh agricultural research station. Crop rotations were included, 1 Wheat monoculture for the whole period (WWWWW, 2 Wheat- wheat- wheat- canola- wheat (WWWCW, 3 Wheat- sugar beet- wheat- potato- wheat (WSWPW, 4 Wheat- maize- wheat- potato- wheat (WMWPW as main plots and three levels of returning crop residues to soil (returning 0, 50 and 100% produced crop residues to soil were allocated as sub plots. This experiment was designed as split plot based on RCBD design with three replications. After ending each rotation treatment, the field was sowed with potato cv. Agria

Development of nondestructive evaluation of creep-fatigue damage in SUS316 stainless steel

International Nuclear Information System (INIS)

Shoji, Tetsuo; Kawahara, Tetsuji; Awano, Masakazu; Sato, Yasumoto

1999-01-01

Creep-fatigue is a fatal failure mode of high temperature structural materials. It is recognized that the law of linear damage, according to which creep-fatigue damage is expressed by the sum of the creep damage and the fatigue damage, is inadequate to evaluate creep-fatigue damage. This is due to the fact that the law of linear damage does not include the effect of interaction between the creep damage and the fatigue damage. Consequently, development of direct measurement of damage accumulation on the sample of interest is required for plant life evaluation. In this study, the induced current focusing potential drop (ICFPD) technique was used to evaluate the depth of small surface cracks in SUS316FR stainless steel which was subjected to creep-fatigue damage. It is shown that the potential drop increased during the micro-crack initiation and propagation. Correspondingly, the ICFPD technique applied to estimate micro-crack depth changes was used to accurately evaluate the residual life of creep-fatigue damaged structural materials. (author)

Finite element modelling of shot peening process: Prediction of the compressive residual stresses, the plastic deformations and the surface integrity

International Nuclear Information System (INIS)

Frija, M.; Hassine, T.; Fathallah, R.; Bouraoui, C.; Dogui, A.

2006-01-01

This paper presents a numerical simulation of the shot peening process using finite element method. The majority of the controlling parameters of the process have been taken into account. The shot peening loading has been characterised by using energy equivalence between the dynamic impact and a static indentation of a peening shot in the treated surface. The behaviour of the subjected material is supposed to be elastic plastic with damage. An integrated law of the damage proposed by Lemaitre and Chaboche has been used. The proposed model leads to obtain the residual stress, the plastic deformation profiles and the surface damage. An application on a shot peened Ni-based super alloy Waspaloy has been carried out. The comparison of the residual stresses, obtained by X-ray diffraction method and by finite element calculation, shows a good correlation. The in-depth profile of the plastic deformations and the superficial damage values are in good agreement with the experimental observations

Fatigue-damage evolution and damage-induced reduction of critical current of a Nb3Al superconducting composite

International Nuclear Information System (INIS)

Ochiai, S; Sekino, F; Sawada, T; Ohno, H; Hojo, M; Tanaka, M; Okuda, H; Koganeya, M; Hayashi, K; Yamada, Y; Ayai, N; Watanabe, K

2003-01-01

We have studied the fatigue-damage mechanism of a Nb 3 Al superconducting composite at room temperature, and the influences of the fatigue damages introduced at room temperature on the critical current at 4.2 K and the residual strength at room temperature. The main (largest) fatigue crack arose first in the clad copper and then extended into the inner core with an increasing number of stress cycles. The cracking of the Nb 3 Al filaments in the core region occurred at a late stage (around 60-90% of the fatigue life). Once the fracture of the core occurred, it extended very quickly, resulting in a quick reduction in critical current and the residual strength with increasing stress cycles. Such a behaviour was accounted for by the crack growth calculated from the S-N curves (the relation of the maximum stress to the number of stress cycles at failure) combined with the Paris law. The size and distribution of the subcracks along the specimen length, and therefore the reduction in critical current of the region apart from the main crack, were dependent on the maximum stress level. The large subcracks causing fracture of the Nb 3 Al filaments were formed when the maximum stress was around 300-460 MPa, resulting in large reduction in critical current, but not when the maximum stress was outside such a stress range

Spectroscopic analyses on interaction of bovine serum albumin (BSA) with toluidine blue (TB) and its sonodynamic damage under ultrasonic irradiation

International Nuclear Information System (INIS)

Wang Jun; Guo Yuwei; Liu Bin; Cheng Chunping; Wang Zhiqiu; Han Guangxi; Gao Jingqun; Zhang Xiangdong

2011-01-01

In this paper, the toluidine blue (TB) with tricyclic quinone imide plane structure is used as sonosensitizer to study the interaction and sonodynamic damage to bovine serum albumin (BSA) by UV-vis and fluorescence spectroscopy. The results show that the TB can bind to BSA molecules, obviously, and the synergetic effects of TB and ultrasonic irradiation can efficiently damage the BSA molecules. Otherwise, some influencing factors such as ultrasonic irradiation time, TB concentration, pH value and ionic strength on the damage of BSA molecules were also considered by the numbers. Synchronous fluorescence spectroscopy indicates that the tyrosine (Tyr) residues of BSA molecules are damaged more seriously than the tryptophan (Trp) residues under ultrasonic irradiation. - Research Highlights: → TB is used as quencher to study interaction to BSA. → TB is used as sonosensitizer to study the sonodynamic damage to BSA. → Synchronous fluorescence spectroscopy is used to study TB binding site to BSA.

A review of experimental methods for determining residual creep life

International Nuclear Information System (INIS)

Bolton, C.J.

1977-11-01

Experimental methods available for determining how much creep life remains at a particular time in the high temperature service of a component are reviewed. After a brief consideration of the limitations of stress rupture extrapolation techniques, the application of post-exposure creep testing is considered. Ways of assessing the effect of microstructural degradation on residual life are then reviewed. It is pointed out that while this type of work will be useful for certain materials, there are other materials in which 'mechanical damage' such as cavitation will be more important. Cavitation measurement techniques are therefore reviewed. The report ends with a brief consideration of the use of crack growth measurements in assessing the residual life of cracked components. (author)

Assesment of Severely ASR Damaged Bridges: From Diagnosis to Structural Effects

DEFF Research Database (Denmark)

Barbosa, Ricardo Antonio; Hansen, Søren Gustenhoff; Hansen, Kurt Kielsgaard

2016-01-01

documented. The majority of the experimental data are based on relatively small scale laboratory specimens accelerated by various exposure conditions. Research on assessment and influence of severely ASR deterioration on the material properties and residual load carrying capacity of real-life structures...... is unfortunately limited. This paper presents an overview and discussion of the Danish experiences with assessment of the residual load carrying capacity of severely non-shear reinforced ASR damaged bridges. The discussion is supported by experimental data acquired from large scale in-situ tests of three severely...

Damage Tolerance of Pre-Stressed Composite Panels Under Impact Loads

Science.gov (United States)

Johnson, Alastair F.; Toso-Pentecôte, Nathalie; Schueler, Dominik

2014-02-01

An experimental test campaign studied the structural integrity of carbon fibre/epoxy panels preloaded in tension or compression then subjected to gas gun impact tests causing significant damage. The test programme used representative composite aircraft fuselage panels composed of aerospace carbon fibre toughened epoxy prepreg laminates. Preload levels in tension were representative of design limit loads for fuselage panels of this size, and maximum compression preloads were in the post-buckle region. Two main impact scenarios were considered: notch damage from a 12 mm steel cube projectile, at velocities in the range 93-136 m/s; blunt impact damage from 25 mm diameter glass balls, at velocities 64-86 m/s. The combined influence of preload and impact damage on panel residual strengths was measured and results analysed in the context of damage tolerance requirements for composite aircraft panels. The tests showed structural integrity well above design limit loads for composite panels preloaded in tension and compression with visible notch impact damage from hard body impact tests. However, blunt impact tests on buckled compression loaded panels caused large delamination damage regions which lowered plate bending stiffness and reduced significantly compression strengths in buckling.

Study of the spallation reactions 136Xe + p and 136Xe + 12C at 1 GeV per nucleon at the GSI facility (Darmstadt, Germany)

International Nuclear Information System (INIS)

Gorbinet, T.

2011-11-01

The collision of 136 Xe with a proton and with 12 C at 1 GeV per nucleon of projectile kinetic energy in the center of mass has been studied in inverse kinematics using the SPALADIN experimental setup at the GSI facility. This manuscript describes the analysis of these collisions realized in spring 2009. The detection in coincidence of the final state fragments (projectile residues, neutrons and light charged fragments) with a large geometrical efficiency is provided by the inverse kinematics combined with a large aperture dipole magnet and large detectors. Such a coincidence, measured on an event basis, allows selecting, in a model independent way, the pre-fragment, the excited nuclear system formed after the intranuclear cascade as a function of its excitation energy. Hence, we were able to study the evolution of the pre-fragment deexcitation mechanism (evaporation of light particles, asymmetric binary decay, multiple fragmentation..) as a function of its excitation energy. The data of the 136 Xe + p reaction have been compared mainly to three deexcitation models (SMM, GEMINI++ and ABLA07) coupled to the intranuclear cascade code INCL4. Despite the relatively good and global agreement between these models and our data, significant discrepancies appeared concerning in particular the production of intermediate mass fragments (IMF). Comparison between the 136 Xe + 12 C and the 136 Xe + p data exhibits an important similarity in the deexcitation of the pre-fragments. This suggests that the nuclear cascade leads, for both targets, to similar pre-fragment types in the range of excitation energy (0 to 4 MeV per nucleon) common to both reactions. Higher excitation energies, reached only in the 136 Xe + 12 C reaction, show a qualitative difference in the deexcitation of the pre-fragment, with much higher multiplicities of IMF per event, increasing with the excitation energy. (author)

High Cycle Fatigue Performance in Laser Shock Peened TC4 Titanium Alloys Subjected to Foreign Object Damage

Science.gov (United States)

Luo, Sihai; Nie, Xiangfan; Zhou, Liucheng; Li, Yiming; He, Weifeng

2018-03-01

During their service, titanium alloys are likely to suffer from the foreign object damage (FOD), resulting in a decrease in their fatigue strength. Laser shock peening (LSP) has been proved to effectively increase the damage tolerance of military engine components by introducing a magnitude compressive residual stress in the near-surface layer of alloys. In this paper, smooth specimens of a TC4 titanium alloy were used and treated by LSP and subsequently exposed to FOD, which was simulated by firing a steel sphere with a nominal velocity of 300 m/s, at 90° with the leading edge of the LSP-treated region using a light gas gun. All impacted specimens were then subjected to fatigue loading. The results showed that LSP could effectively improve the fatigue strength of the damaged specimens. The effect of LSP on the fatigue strength was assessed through fracture observations, microhardness tests and residual stress analyses. The residual stresses due to the plastic deformation caused by LSP and the FOD impact, which were found to play a crucial role on the fatigue strength, were determined using the commercial software ABAQUS.

Improved assay for thymine base damage in E. coli using high performance liquid chromatography

International Nuclear Information System (INIS)

Claycamp, H.G.

1985-01-01

A simple high performance liquid chromatography (HPLC) technique has been established for the simultaneous assay of thymine and thymidine radiation damage products. The HPLC procedure uses an isocratic mobile phase of 4% acetonitrile in 0.2 M ammonium dihydrogen phosphate (pH 5.0), a reversed-phase octadecylsilicate (5 micro-spherical packing) 0.45 x 25 cm column, and a variable wavelength UV detector. This procedure affords much better resolution than other published procedures that use 10 micron columns or separate assays for bases and nucleosides. For example, irradiation of 5 x 10 -3 M thymidine solutions have been performed to calibrate the system for base damage assays in E. coli. This yields up to 15 resolvable residues within 20 minutes. Sensitivity of the system (at 2210 nm) for 5,6- dihydrothymine (DHT) is about 10 -10 moles. Preliminary results show that this translates to about 0.4 DHT residues per 10 6 daltons of E. coli DNA. This is comparable to the sensitivities of monoclonal assays to thymine damage products that have recently been reported by others. Since it is feasible that the sensitivity of this system can be improved by 2-3 times, this HPLC technique should provide a simple and rapid means of detecting E. coli base damage release and base damage in nucleoside hydrolysates of DNA

Feasibility study on longitudinal phase-space measurements at GSI UNILAC using charged-particle detectors

Energy Technology Data Exchange (ETDEWEB)

Milosic, Timo

2014-04-14

Accelerator facilities require access to many beam parameters during operation. The field of beam instrumentation serves this crucial role in commissioning, setup and optimisation of the facility. An important information is contained in the phase-space distribution of the accelerated particles. In case of GSI (Helmholtzzentrum fuer Schwerionenforschung) those are ions from protons to uranium. If established methods to access certain beam parameters do not exist, new approaches have to emerge. This is the case for the presented measurement setup which has been designed and realised by Forck et al. to support commissioning of the GSI high-current injector. It is aiming at an experimental method to access the longitudinal phase-space distribution at low energies of 1.4 AMeV. Established methods for higher energies and based on the measurement of the electric field distribution are not feasible at non-relativistic velocities. The presented method is based on a time-of-flight (TOF) measurement between two particle detectors. A modification allows, alternatively, the direct measurement of the kinetic energy using a mono-crystalline (MC) diamond detector. Currently, besides others, the focus of the optimisation of the injector is put on the longitudinal phase-space distribution. It allows for a systematic optimisation of the matching into the accelerator cavities and, thus, an improved transmission as well as lower emittance values. The new accelerator facility FAIR (Facility for Antiproton and Ion Research), a large-scale upgrade at GSI, requires an improved beam quality at the existing injector. In this work the experimental setup is investigated for its feasibility to measure the longitudinal phase-space distribution. To this end, the phase and momentum of the single ions along the beam axis have to be determined with high precision. Finally, the longitudinal phase-space distribution is identified with the measured ensemble. The setup is presented in detail

Determination of global and local residual stresses in SOFC by X-ray diffraction

International Nuclear Information System (INIS)

Villanova, Julie; Sicardy, Olivier; Fortunier, Roland; Micha, Jean-Sebastien; Bleuet, Pierre

2010-01-01

Solid Oxide Fuel Cell (SOFC) is a high-performance electrochemical device for energy conversion. A single cell is composed of five layers made of different ceramic materials: anode support, anode functional layer, electrolyte, cathode functional layer and cathode. The mechanical integrity of the cell is a major issue during its lifetime, especially for the electrolyte layer. Damage of the cells is mainly due to the high operating temperature, the 'redox' behaviour of the anode and the brittleness of the involved materials. Since residual stresses are known to play a significant role in the damage evolution, it is important to determine them. For this purpose, residual stresses in an anode-supported planar SOFC were measured by X-ray diffraction. Firstly, macroscopic stresses in each phase of each layer were studied using the sin 2 ψ method on a laboratory X-ray goniometer at room temperature. This technique enables the calculation of residual stress of the material from the measurement of the crystal lattice deformation. The electrolyte has been found under bi-axial compressive stress of -920 MPa. Secondly, X-ray measurements controlling depth penetration were made in the electrolyte using grazing incidence method. The results show that the stress is not homogenous in the layer. The first five micrometers of the electrolyte have been found less constrained (-750 MPa) than the complete layer, suggesting a gradient of deformation in the electrolyte from the interface with the Anode Functional Layer to the free surface. Finally, local stress measurements were made on the electrolyte layer by X-ray synchrotron radiation that allows high accuracy measurement on the (sub-) micrometer scale. Polychromatic and monochromatic beams are used to determine the complete strain tensor from grain to grain in the electrolyte. First results confirm the macroscopic stress trend of the electrolyte. These X-ray techniques at different scales will contribute to a better understanding

A study for the domestic application plan of the Generic Safety Issue(GSI) for the Pressurized Heavy Water Reactor

International Nuclear Information System (INIS)

Lee, Un Chul; Jang, Jin Wook; Lee, Sang Kyung; Lee, Doo Yong; Park, Chang Hwan

2002-03-01

In this study, a base work to construct the database of the domestic and foreign GSls were done through performing the deviation of GSls for the PHWR by investigating the development trend of international joint studies and the GSls of 4 countries as the PHWR state and examined the IAEA acceptance of GSls classification for the GSls of Canada, Korea Republic of, Argentina and India. We evaluated the possibility of application of the safety Issue for PHWR by investigating causes, contents and follow-up measures of each items. To evaluate the domestic application validity of the safety issue, We made the investigation matrix for the safety issue of each countries and also are reflecting new results in investigation matrix by examining IAEA PHWR GSI development trend. We intended to derive the GSls which are most appropriate in our PHWR by examining every issues. the derived GSls are divided into the design parts and the operation parts. And they have to be solved as soon as possible

A study for the domestic application plan of the Generic Safety Issue(GSI) for the Pressurized Heavy Water Reactor

Energy Technology Data Exchange (ETDEWEB)

Lee, Un Chul; Jang, Jin Wook; Lee, Sang Kyung; Lee, Doo Yong; Park, Chang Hwan [Seoul National Univ., Seoul (Korea, Republic of)

2002-03-15

In this study, a base work to construct the database of the domestic and foreign GSls were done through performing the deviation of GSls for the PHWR by investigating the development trend of international joint studies and the GSls of 4 countries as the PHWR state and examined the IAEA acceptance of GSls classification for the GSls of Canada, Korea Republic of, Argentina and India. We evaluated the possibility of application of the safety Issue for PHWR by investigating causes, contents and follow-up measures of each items. To evaluate the domestic application validity of the safety issue, We made the investigation matrix for the safety issue of each countries and also are reflecting new results in investigation matrix by examining IAEA PHWR GSI development trend. We intended to derive the GSls which are most appropriate in our PHWR by examining every issues. the derived GSls are divided into the design parts and the operation parts. And they have to be solved as soon as possible.

The Persian Gulf: pollution, damage assessment, damage evaluation. Detection of environmental changes after oil spill. Final report

International Nuclear Information System (INIS)

Graf, G.

1993-01-01

During a cruise in december 1991 postwar environmental damage was assessed in the nothern Persian Gulf. The sediments contained apparent traces of oil residues. Extremely high sediment oxygen demand cannot be explained by oil pollution. Sufficient aeriation of the water column is ensured by the hydrographical setting in the area. Since large macrofauna species are very little abundant, the benthic biomass dominated by bacteria. Due to this shift in the size distribution of the benthic community, changes of the whole ecosystem are most likely. (orig.) [de

Quadratic residues and non-residues selected topics

CERN Document Server

Wright, Steve

2016-01-01

This book offers an account of the classical theory of quadratic residues and non-residues with the goal of using that theory as a lens through which to view the development of some of the fundamental methods employed in modern elementary, algebraic, and analytic number theory. The first three chapters present some basic facts and the history of quadratic residues and non-residues and discuss various proofs of the Law of Quadratic Reciprosity in depth, with an emphasis on the six proofs that Gauss published. The remaining seven chapters explore some interesting applications of the Law of Quadratic Reciprocity, prove some results concerning the distribution and arithmetic structure of quadratic residues and non-residues, provide a detailed proof of Dirichlet’s Class-Number Formula, and discuss the question of whether quadratic residues are randomly distributed. The text is a valuable resource for graduate and advanced undergraduate students as well as for mathematicians interested in number theory.

The prediction of reliability and residual life of reactor pressure components

International Nuclear Information System (INIS)

Nemec, J.; Antalovsky, S.

1978-01-01

The paper deals with the problem of PWR pressure components reliability and residual life evaluation and prediction. A physical model of damage cumulation which serves as a theoretical basis for all considerations presents two major aspects. The first one describes the dependence of the degree of damage in the crack leading-edge in pressure components on the reactor system load-time history, i.e. on the number of transient loads. Both stages, fatigue crack initiation and growth through the wall until the critical length is reached, are investigated. The crack is supposed to initiate at the flaws in a strength weld joint or in the bimetallic weld of the base ferritic steel and the austenitic stainless overlay cladding. The growth rates of developed cracks are analysed in respect to different load-time histories. Important cyclic properties of some steels are derived from the low-cycle fatigue theory. The second aspect is the load-time history-dependent process of precipitation, deformation and radiation aging, characterized entirely by the critical crack-length value mentioned above. The fracture point, defined by the equation ''crack-length=critical value'' and hence the residual life, can be evaluated using this model and verified by in-service inspection. The physical model described is randomized by considering all the parameters of the model as random. Monte Carlo methods are applied and fatigue crack initiation and growth is simulated. This permits evaluation of the reliability and residual life of the component. The distributions of material and load-time history parameters are needed for such simulation. Both the deterministic and computer-simulated probabilistic predictions of reliability and residual life are verified by prior-to-failure sequential testing of data coming from in-service NDT periodical inspections. (author)

Experimental Analysis of Residual Stresses in Samples of Austenitic Stainless Steel Welded on Martensitic Stainless Steel Used for Kaplan Blades Repairs

Directory of Open Access Journals (Sweden)

Vasile Cojocaru

2011-01-01

Full Text Available Residual stresses occur in materials as a result of mechanical processes: welding, machining, grinding etc. If residual stresses reach high values they can accelerate the occurrence of cracks and erosion of material. An experimental research was made in order to study the occurrence of residual stresses in the repaired areas of hydraulic turbine components damaged by cavitation erosion. An austenitic stainless steel was welded in various layer thicknesses on a martensitic stainless steel base. The residual stresses were determined using the hole drilling strain gage method.

Design and study of new cables for superconducting accelerator magnets: Synchrotron SIS 100 at GSI and NICA collider at JINR*

International Nuclear Information System (INIS)

Khodzhibagiyan, H G; Drobin, V M; Kovalenko, A D; Vladimirova, N M; Fischer, E; Pantsyrny, V I; Potanina, L V; Shikov, A K

2010-01-01

Recent data from the design of new optimized options of NbTi composite wires and hollow cables for fast cycling synchrotron SIS100 at GSI and NICA collider at JINR are presented. The SIS100 new cable is proposed to be used for manufacturing of single-layer coil for dipole magnet with maximal amplitude of pulsed magnetic field up to 2 T. The cable should provide continues pulsed operation at the current amplitude of I = 13 kA and magnetic field ramp rate of dB/dt = 4 T/s. The results of experimental study of energy losses in the new wire and cable samples for SIS100 magnets are presented. The design cable parameters for the NICA 4 T dipole magnet are fixed at the level of I = 17 kA and dB/dt = 1 T/s. The status of the work is presented and discussed.

Synchrotron X-ray measurement of residual strain within the nose of a worn manganese steel railway crossing

Science.gov (United States)

Dhar, S.; Zhang, Y.; Xu, R.; Danielsen, HK; Jensen, D. Juul

2017-07-01

Switches and crossings are an integral part of any railway network. Plastic deformation associated with wear and rolling contact fatigue due to repeated passage of trains cause severe damage leading to the formation of surface and sub-surface cracks which ultimately may result in rail failure. Knowledge of the internal stress distribution adds to the understanding of crack propagation and may thus help to prevent catastrophic rail failures. In this work, the residual strains inside the bulk of a damaged nose of a manganese railway crossing that was in service for five years has been investigated by using differential aperture synchrotron X-ray diffraction. The main purpose of this paper is to describe how this method allows non-destructive measurement of residual strains in selected local volumes in the bulk of the rail. Measurements were conducted on the transverse surface at a position about 6.5 mm from the rail running surface of a crossing nose. The results revealed the presence of significant compressive residual strains along the running direction of the rail.

The reaction {sup 48}Ca+{sup 238}U {yields}{sup 286}112{sup *} studied at the GSI-SHIP

Energy Technology Data Exchange (ETDEWEB)

Hofmann, S. [Gesellschaft fuer Schwerionenforschung (GSI), D-64291 Darmstadt (Germany); Institut fuer Kernphysik, Johann Wolfgang Goethe-Universitaet, Frankfurt (Germany); Ackermann, D.; Burkhard, H.G.; Heinz, S.; Hessberger, F.P.; Khuyagbaatar, J.; Kindler, B.; Kojouharov, I.; Lommel, B.; Mann, R.; Muenzenberg, G.; Schoett, H.J.; Sulignano, B. [Gesellschaft fuer Schwerionenforschung (GSI), Darmstadt (Germany); Antalic, S.; Saro, S.; Streicher, B.; Venhart, M. [Comenius University, Department of Nuclear Physics and Biophysics, Bratislava (Slovakia); Comas, V.F.; Heredia, J.A. [InSTEC, Habana (Cuba); Dressler, R. [Paul Scherrer Institute, Villigen (Switzerland); Gan, Z. [Chinese Academy of Sciences, Institute of Modern Physics, Lanzhou (China); Kuusiniemi, P. [University of Oulu, CUPP (Finland); Leino, M.; Uusitalo, J. [University of Jyvaeskylae, Department of Physics, Jyvaeskylae (Finland); Nishio, K. [Japan Atomic Energy Agency, Tokai, Ibaraki (Japan); Popeko, A.G.; Yeremin, A.V. [JINR, Flerov Laboratory of Nuclear Reactions, Dubna (Russian Federation)

2007-06-15

The fusion reaction of {sup 48}Ca projectiles with {sup 238}U target nuclei was studied at the velocity filter SHIP of GSI in Darmstadt. Two decay chains were measured, which fully confirm data that were previously assigned to the isotope {sup 283}112 in experiments at the Flerov Laboratory in Dubna. Two other events are consistent with a 50% spontaneous-fission (SF) branch of this isotope. The mean value obtained for the half-life of {sup 283}112 is (6.9{sup +6.9}{sub -2.3}) s, the {alpha} energy is (9.520{+-}0.015) MeV, and the total kinetic energy (TKE) of SF is (238{+-}14) MeV. The half-life of the {alpha} decay daughter nucleus {sup 279}Ds is (0.18{sup +0.32}{sub -0.07}) s, and the TKE of SF is (210 {sup +32}{sub -11}) MeV. The cross-section deduced from all four events is (0.72{sup +0.58}{sub -0.35}) pb, measured at an excitation energy of 34.6MeV of the compound nucleus {sup 286}112. (orig.)

Influence of MSD crack pattern on the residual strength of flat stiffened sheets

Science.gov (United States)

Nilsson, K.-F.

A parameter study of the residual strength for a multiple site damaged (MSD) stiffened sheet is presented. The analysis is based on an elastic-plastic fracture analysis using the yield-strip model for interaction between a lead crack and the smaller MSD cracks. Two crack growth criteria, one with a pronounced crack growth resistance and one with no crack growth resistance and five different MSD crack patterns, are analysed for different sizes of the lead crack and the smaller MSD cracks. The analysis indicates that the residual strength reduction depends on all these parameters and that MSD may totally erode the crack arrest capability of a tear strap. Another important outcome is that for certain combinations also very small MSD cracks may induce a significant residual strength reduction.

Characterization and damage evaluation of advanced materials

Science.gov (United States)

Mitrovic, Milan

Mechanical characterization of advanced materials, namely magnetostrictive and graphite/epoxy composite materials, is studied in this dissertation, with an emphasis on damage evaluation of composite materials. Consequently, the work in this dissertation is divided into two parts, with the first part focusing on characterization of the magneto-elastic response of magnetostrictlve materials, while the second part of this dissertation describes methods for evaluating the fatigue damage in composite materials. The objective of the first part of this dissertation is to evaluate a nonlinear constitutive relation which more closely depict the magneto-elastic response of magnetostrictive materials. Correlation between experimental and theoretical values indicate that the model adequately predicts the nonlinear strain/field relations in specific regimes, and that the currently employed linear approaches are inappropriate for modeling the response of this material in a structure. The objective of the second part of this dissertation is to unravel the complexities associated with damage events associated with polymeric composite materials. The intent is to characterize and understand the influence of impact and fatigue induced damage on the residual thermo-mechanical properties and compressive strength of composite systems. The influence of fatigue generated matrix cracking and micro-delaminations on thermal expansion coefficient (TEC) and compressive strength is investigated for woven graphite/epoxy composite system. Experimental results indicate that a strong correlation exists between TEC and compressive strength measurements, indicating that TEC measurements can be used as a damage metric for this material systems. The influence of delaminations on the natural frequencies and mode shapes of a composite laminate is also investigated. Based on the changes of these parameters as a function of damage, a methodology for determining the size and location of damage is suggested

Inter-individual and inter-cell type variation in residual DNA damage after in vivo irradiation of human skin

International Nuclear Information System (INIS)

Chua, Melvin Lee Kiang; Somaiah, Navita; Bourne, Sara; Daley, Frances; A'Hern, Roger; Nuta, Otilia; Davies, Sue; Herskind, Carsten; Pearson, Ann; Warrington, Jim; Helyer, Sarah; Owen, Roger; Yarnold, John; Rothkamm, Kai

2011-01-01

Purpose: The aim of this study was to compare inter-individual and inter-cell type variation in DNA double-strand break (DSB) repair following in vivo irradiation of human skin. Materials and methods: Duplicate 4 mm core biopsies of irradiated and unirradiated skin were collected from 35 patients 24 h after 4 Gy exposure using 6 MeV electrons. Residual DSB were quantified by scoring 53BP1 foci in dermal fibroblasts, endothelial cells, superficial keratinocytes and basal epidermal cells. Results: Coefficients of inter-individual variation for levels of residual foci 24 h after in vivo irradiation of skin were 39.9% in dermal fibroblasts, 44.3% in endothelial cells, 32.9% in superficial keratinocytes and 46.4% in basal epidermal cells (p < 0.001, ANOVA). In contrast, the coefficient of inter-cell type variation for residual foci levels was only 11.3% in human skin between the different epidermal and dermal cells (p = 0.034, ANOVA). Foci levels between the different skin cell types were correlated (Pearson's R = 0.855-0.955, p < 0.001). Conclusions: Patient-specific factors appear to be more important than cell type-specific factors in determining residual foci levels following in vivo irradiation of human skin.

Cointegration approach for temperature effect compensation in Lamb-wave-based damage detection

International Nuclear Information System (INIS)

Dao, Phong B; Staszewski, Wieslaw J

2013-01-01

Lamb waves are often used in smart structures with integrated, low-profile piezoceramic transducers for damage detection. However, it is well known that the method is prone to contamination from a variety of interference sources including environmental and operational conditions. The paper demonstrates how to remove the undesired temperature effect from Lamb wave data. The method is based on the concept of cointegration that is partially built on the analysis of the non-stationary behaviour of time series. Instead of directly using Lamb wave responses for damage detection, two approaches are proposed: (i) analysis of cointegrating residuals obtained from the cointegration process of Lamb wave responses, (ii) analysis of stationary characteristics of Lamb wave responses before and after cointegration. The method is tested on undamaged and damaged aluminium plates exposed to temperature variations. The experimental results show that the method can: isolate damage-sensitive features from temperature variations, detect the existence of damage and classify its severity. (paper)

Modeling the Non-Linear Response of Fiber-Reinforced Laminates Using a Combined Damage/Plasticity Model

Science.gov (United States)

Schuecker, Clara; Davila, Carlos G.; Pettermann, Heinz E.

2008-01-01

The present work is concerned with modeling the non-linear response of fiber reinforced polymer laminates. Recent experimental data suggests that the non-linearity is not only caused by matrix cracking but also by matrix plasticity due to shear stresses. To capture the effects of those two mechanisms, a model combining a plasticity formulation with continuum damage has been developed to simulate the non-linear response of laminates under plane stress states. The model is used to compare the predicted behavior of various laminate lay-ups to experimental data from the literature by looking at the degradation of axial modulus and Poisson s ratio of the laminates. The influence of residual curing stresses and in-situ effect on the predicted response is also investigated. It is shown that predictions of the combined damage/plasticity model, in general, correlate well with the experimental data. The test data shows that there are two different mechanisms that can have opposite effects on the degradation of the laminate Poisson s ratio which is captured correctly by the damage/plasticity model. Residual curing stresses are found to have a minor influence on the predicted response for the cases considered here. Some open questions remain regarding the prediction of damage onset.

Photorepair of UV damage to DNA: purification and properties of DNA photolyase (the DNA-photoreactivating enzyme). Progress report, August 1, 1975--July 31, 1976

International Nuclear Information System (INIS)

Werbin, H.

1976-01-01

Progress is reported on the following research projects: separation of photolyase subunits by sucrose gradient sedimentation; determination of whether fluorescent material is the chromophore for photolyase; studies on tryptophane and lysine residues to determine whether these are involved in the binding and photolytic steps; nmr spectrum of activator of photolyase; damage to pea chromatin by solar near uv and repair of damage; tryptophan residues in yeast DNA photolyase; photolyase in pea seedlings; and nuclear magnetic resonance spectra of purified activator

Nondestructive Damage Evaluation in Ceramic Matrix Composites for Aerospace Applications

Directory of Open Access Journals (Sweden)

Konstantinos G. Dassios

2013-01-01

Full Text Available Infrared thermography (IRT and acoustic emission (AE are the two major nondestructive methodologies for evaluating damage in ceramic matrix composites (CMCs for aerospace applications. The two techniques are applied herein to assess and monitor damage formation and evolution in a SiC-fiber reinforced CMC loaded under cyclic and fatigue loading. The paper explains how IRT and AE can be used for the assessment of the material’s performance under fatigue. IRT and AE parameters are specifically used for the characterization of the complex damage mechanisms that occur during CMC fracture, and they enable the identification of the micromechanical processes that control material failure, mainly crack formation and propagation. Additionally, these nondestructive parameters help in early prediction of the residual life of the material and in establishing the fatigue limit of materials rapidly and accurately.

Antibiotics threaten wildlife: circulating quinolone residues and disease in Avian scavengers.

Directory of Open Access Journals (Sweden)

Jesús A Lemus

Full Text Available Antibiotic residues that may be present in carcasses of medicated livestock could pass to and greatly reduce scavenger wildlife populations. We surveyed residues of the quinolones enrofloxacin and its metabolite ciprofloxacin and other antibiotics (amoxicillin and oxytetracycline in nestling griffon Gyps fulvus, cinereous Aegypius monachus and Egyptian Neophron percnopterus vultures in central Spain. We found high concentrations of antibiotics in the plasma of many nestling cinereous (57% and Egyptian (40% vultures. Enrofloxacin and ciprofloxacin were also found in liver samples of all dead cinereous vultures. This is the first report of antibiotic residues in wildlife. We also provide evidence of a direct association between antibiotic residues, primarily quinolones, and severe disease due to bacterial and fungal pathogens. Our results indicate that, by damaging the liver and kidney and through the acquisition and proliferation of pathogens associated with the depletion of lymphoid organs, continuous exposure to antibiotics could increase mortality rates, at least in cinereous vultures. If antibiotics ingested with livestock carrion are clearly implicated in the decline of the vultures in central Spain then it should be considered a primary concern for conservation of their populations.

Modeling event building architecture for the triggerless data acquisition system for PANDA experiment at the HESR facility at FAIR/GSI

CERN Multimedia

CERN. Geneva

2012-01-01

A novel architecture is being proposed for the data acquisition and trigger system for PANDA experiment at the HESR facility at FAIR/GSI. The experiment will run without the hardware trigger signal and use timestamps to correlate detector data from a given time window. The broad physics program in combination with high rate of 2 10^7 interactions require very selective filtering algorithms which access information from almost all detectors. Therefore the effective filtering will happen later than it used to in today's systems ie after the event building. To assess that, the complete architecture will be built of two stages: the data concentrator stage providing event building and the rate reduction stage. For the former stage, which allows to switch 100 GB/s of event fragments to perform event building, we propose two layers of ATCA crates filled with compute nodes - modules designed at University of Giessen for trigger and data acquisition systems. Each board is equipped with 5 Virtex4 FX60 FPG...

Dityrosine, 3,4-Dihydroxyphenylalanine (DOPA), and radical formation from tyrosine residues on milk proteins with globular and flexible structures as a result of riboflavin-mediated photo-oxidation

DEFF Research Database (Denmark)

Dalsgaard, Trine Kastrup; Nielsen, Jacob Holm; Brown, Bronwyn

2011-01-01

Riboflavin-mediated photo-oxidative damage to protein Tyr residues has been examined to determine whether protein structure influences competing protein oxidation pathways in single proteins and protein mixtures. EPR studies resulted in the detection of Tyr-derived o-semiquione radicals, with thi......Riboflavin-mediated photo-oxidative damage to protein Tyr residues has been examined to determine whether protein structure influences competing protein oxidation pathways in single proteins and protein mixtures. EPR studies resulted in the detection of Tyr-derived o-semiquione radicals...

Cross-sections of spallation residues produced in Proton –Induced reactions

International Nuclear Information System (INIS)

Al-Haydari, A.; Khan, A.A.; Abdul Ganai, A.; Hassan, G.S.

2013-01-01

The recent available GSI data for proton-induced spallation reactions by using inverse kinematics at different energies are analyzed for different reactions in terms of the percolation model together with the intranuclear cascade model (MCAS). The simulation results obtained for the cross sections of production of light ions and isotopes as a function of mass and charge number is calculated. Results of calculations are in good agreement with experiment

Improvement of residual stress in stainless steel by cavitating jet; Cavitation funryu ni yoru stainless ko no zanryu oryoku kaizen

Energy Technology Data Exchange (ETDEWEB)

Soyama, H.; Saka, M. [Tohoku Univ., Sendai (Japan)] Park, J. [Kyung Nam Junior College, Pusan (Korea, Republic of). Dept. Vehicle Eng.] Abe, H. [Tohoku Univ., Sendai (Japan)

1998-08-15

In order to strengthen materials, the improvement of residual stress in stainless steel by using a cavitating jet was investigated. In case of cavitating jet, the cavitation intensity can be controlled by hydraulic parameters such as upstream pressure and downstream pressure. In general, cavitation produces damage on hydraulic machinery. However, at the initial stage of cavitation erosion process, plastic deformation takes place on the material surface, then it is possible to do peening without damage considering the cavitation intensity and the exposure time. In order to evidence the suitable condition on the improvement of residual stress by the cavitating jet, the residual stress in SUS304 and SUS316 was examined. The three normal stresses in different directions were measured by X-ray diffraction method, then the principal stresses were calculated. Both principal stresses were changed from tension to compression within 10 seconds by the cavitating jet. The compressive stress resulted by the cavitating jet was saturated after a certain time. It was concluded that the cavitating jet improved the residual stress in stainless steel SUS316 as well as SUS304. 24 refs., 9 figs.

Selection of regularization parameter for l1-regularized damage detection

Science.gov (United States)

Hou, Rongrong; Xia, Yong; Bao, Yuequan; Zhou, Xiaoqing

2018-06-01

The l1 regularization technique has been developed for structural health monitoring and damage detection through employing the sparsity condition of structural damage. The regularization parameter, which controls the trade-off between data fidelity and solution size of the regularization problem, exerts a crucial effect on the solution. However, the l1 regularization problem has no closed-form solution, and the regularization parameter is usually selected by experience. This study proposes two strategies of selecting the regularization parameter for the l1-regularized damage detection problem. The first method utilizes the residual and solution norms of the optimization problem and ensures that they are both small. The other method is based on the discrepancy principle, which requires that the variance of the discrepancy between the calculated and measured responses is close to the variance of the measurement noise. The two methods are applied to a cantilever beam and a three-story frame. A range of the regularization parameter, rather than one single value, can be determined. When the regularization parameter in this range is selected, the damage can be accurately identified even for multiple damage scenarios. This range also indicates the sensitivity degree of the damage identification problem to the regularization parameter.

A new coupled elastoplastic damage model for clay-stone and its parameter identification

International Nuclear Information System (INIS)

Jia, S.P.; Chen, W.Z.; Yu, H.D.; Li, X.L.; Sillen, X.

2010-01-01

Document available in extended abstract form only. In Belgium, the Boom Clay is considered as a potential host rock for the geological disposal of the high level nuclear waste and is intensively studied from hydro-mechanical point of view. Laboratory tests on Boom clay shown that the Boom clay presents very complex stress strain behaviour. Undrained triaxial tests indicated often a hardening behaviour at small deformation and softening at larger deformation. It is not easy to give an explicit function to describe the stress-strain behaviour under triaxial stress state. The mechanical characteristics are obviously affected by the porosity, fractures growth, water content, and stress, etc., four stages can be usually distinguished from the stress-strain curve of Boom Clay, named as OA, AB, BC and CD. 1) Stage OA, the relation between stress and strain is linear. This stage is elastic state, and point A is called as yield strength σ c0 . 2) Stage AB, the weak fractures in the rock appear, develop and cumulate gradually. Point B is called peak strength σ cu . 3) Stage BC, peak strength is reached and stress reduces with the increasing of strain, up to the residual strength. This stage is called strain softening and point C is the residual strength σ cr . The axial pressure causes the fracture developing and strength reducing. 4) Stage CD, the final strength doesn't reduce obviously with the development of plastic deformation. This stage is called plastic flow. Obviously, The conventional elasto-plastic constitutive model can not describe the mechanical behaviours of Boom Clay. Based on damage mechanics theory, an new elasto-plastic damage constitutive model is put forward and applied to Boom Clay, which can describe the complex stress-strain behaviour of clay. It is described as follows: stage OA with an elastic model, stage AB with elastic damage model, stage BC and stage CD with plastic damage model. The complete process curve of stress-strain can be divided

Finite element analysis for prediction of the residual stresses induced by shot peening II

International Nuclear Information System (INIS)

Kim, Cheol; Seok, Chang Sung; Yang, Won Ho; Ryu, Myung Hai

2002-01-01

Shot peening is a surface impact treatment widely used to improve the performance of metal parts and welded details subjected to fatigue loading, contact fatigue, stress corrosion and other damage mechanisms. The better performance of the peened parts is mainly due to the residual stresses resulting from the plastic deformation of the surface layers of the material caused by the impact of the shot. In this paper the simulation technique is applied to predict the magnitude and distribution of the residual stress and plastic deformation caused by shot peening with the help of finite element analysis

Colorimetric detection of DNA damage by using hemin-graphene nanocomposites

Science.gov (United States)

Wei, W.; Zhang, D. M.; Yin, L. H.; Pu, Y. P.; Liu, S. Q.

2013-04-01

A colorimetric method for detection of DNA damage was developed by using hemin-graphene nanosheets (H-GNs). H-GNs were skillfully synthesized by adsorping of hemin on graphene through π-π interactions. The as-prepared H-GNs possessed both the ability of graphene to differentiate the damage DNA from intact DNA and the catalytic action of hemin. The damaged DNA made H-GNs coagulated to different degrees from the intact DNA because there were different amount of negative charge exposed on their surface, which made a great impact on the solubility of H-GNs. As a result, the corresponding centrifugal supernatant of H-GNs solution showed different color in the presence of 3,3',5,5'-tetramethylbenzidine (TMB) and H2O2, which could be discriminated by naked eyes or by ultraviolet (UV)-visible spectrometer. Based on this, the damaged effects of styrene oxide (SO), NaAsO2 and UV radiation on DNA were studied. Results showed that SO exerted most serious damage effect on DNA although all of them damaged DNA seriously. The new method for detection of DNA damage showed good prospect in the evaluation of genotoxicity of new compounds, the maximum limit of pesticide residue, food additives, and so on, which is important in the fields of food science, pharmaceutical science and pesticide science.

Cellular bases of radiation-induced residual insufficiency in the haematopoietic system

International Nuclear Information System (INIS)

Wangenheim, K.H. v.; Peterson, H.P.; Feinendegen, L.E.

1984-01-01

Following radiation exposure, man's survival and further well-being largely depends on the degree of damage to his heamatopietic system. Stem cells are particualarly sensitive to radiation. Over and beyond acute radiation damge, residual radiation damage is of significance since it reduces the performance of the haematopietic system and enhances the risk of leukaemia. Knowledge concerning cellular bases may be important for preventive and therapeutic measures. The measurement method presented is based on the fact that stem cells from transfused bone marrow will settle in the spleen of highly irradiated mice and be able to reconstruct the haematopietic system. Initally individual colonies can be observed which originate from a single stem cell and the proliferation of its descendants. Counting these colonies will give the number of stem cells. The reduction of the proliferation factor measured in the stem-cell quality test apparently is not due to a shift in the age structure of the stem cell compartment but to a damage which is located within a more or less substantial proportion of the stem cells themselves. This damage is the cause of stem cell descendant growth retarded on an average. It is probable that recovery observed after irradiation is brought about by less-damaged or undamaged stem cells replacing damaged ones. Initial results point to the fact that this replacement can be influenced by treatment after irradiation. (orig./MG) [de

Numerical weld modeling - a method for calculating weld-induced residual stresses

International Nuclear Information System (INIS)

Fricke, S.; Keim, E.; Schmidt, J.

2001-01-01

In the past, weld-induced residual stresses caused damage to numerous (power) plant parts, components and systems (Erve, M., Wesseling, U., Kilian, R., Hardt, R., Bruemmer, G., Maier, V., Ilg, U., 1994. Cracking in Stabilized Austenitic Stainless Steel Piping of German Boiling Water Reactors - Characteristic Features and Root Causes. 20. MPA-Seminar 1994, vol. 2, paper 29, pp.29.1-29.21). In the case of BWR nuclear power plants, this damage can be caused by the mechanism of intergranular stress corrosion cracking in austenitic piping or the core shroud in the reactor pressure vessel and is triggered chiefly by weld-induced residual stresses. One solution of this problem that has been used in the past involves experimental measurements of residual stresses in conjunction with weld optimization testing. However, the experimental analysis of all relevant parameters is an extremely tedious process. Numerical simulation using the finite element method (FEM) not only supplements this method but, in view of modern computer capacities, is also an equally valid alternative in its own right. This paper will demonstrate that the technique developed for numerical simulation of the welding process has not only been properly verified and validated on austenitic pipe welds, but that it also permits making selective statements on improvements to the welding process. For instance, numerical simulation can provide information on the starting point of welding for every weld bead, the effect of interpass cooling as far as a possible sensitization of the heat affected zone (HAZ) is concerned, the effect of gap width on the resultant weld residual stresses, or the effect of the 'last pass heat sink welding' (welding of the final passes while simultaneously cooling the inner surface with water) producing compressive stresses in the root area of a circumferential weld in an austenitic pipe. The computer program FERESA (finite element residual stress analysis) was based on a commercially

X-ray spectroscopy of warm and hot electron components in the CAPRICE source plasma at EIS testbench at GSI.

Science.gov (United States)

Mascali, D; Celona, L; Maimone, F; Maeder, J; Castro, G; Romano, F P; Musumarra, A; Altana, C; Caliri, C; Torrisi, G; Neri, L; Gammino, S; Tinschert, K; Spaedtke, K P; Rossbach, J; Lang, R; Ciavola, G

2014-02-01

An experimental campaign aiming to detect X radiation emitted by the plasma of the CAPRICE source - operating at GSI, Darmstadt - has been carried out. Two different detectors (a SDD - Silicon Drift Detector and a HpGe - hyper-pure Germanium detector) have been used to characterize the warm (2-30 keV) and hot (30-500 keV) electrons in the plasma, collecting the emission intensity and the energy spectra for different pumping wave frequencies and then correlating them with the CSD of the extracted beam measured by means of a bending magnet. A plasma emissivity model has been used to extract the plasma density along the cone of sight of the SDD and HpGe detectors, which have been placed beyond specific collimators developed on purpose. Results show that the tuning of the pumping frequency considerably modifies the plasma density especially in the warm electron population domain, which is the component responsible for ionization processes: a strong variation of the plasma density near axis region has been detected. Potential correlations with the charge state distribution in the plasma are explored.

Can `loss and damage' carry the load?

Science.gov (United States)

Verchick, Robert R. M.

2018-05-01

Even assuming a heroic rush towards carbon reduction and adaptation, some regions of the world will be hammered hard by climate impacts. Thus, a global consensus now sees the need for a supplemental plan to deal with the kind of harms that cannot be avoided-what Parties call `loss and damage'. For a loss-and-damage plan to work, it must be capable of carrying the load, the load being whatever minimal standards that morality and political consensus require. But if residual risk climbs too high, it will fall short of even the most basic expectations. The Paris Agreement calls for holding the rise in global average temperature to `well below 2°C above pre-industrial levels', while working to limit the increase to 1.5°C. How much difference is in that half-degree? From the point of view of residual risk, quite a lot. According to a 2016 study published by the European Geosciences Union, a jump from 1.5°C to 2°C could produce outsize impacts, particularly in tropical latitudes. That difference could mark the line between a plan that is politically and morally defensible and one that is not. At the very least, the difference is enough to inform the design and expectations of any future plan. This article is part of the theme issue `The Paris Agreement: understanding the physical and social challenges for a warming world of 1.5°C above pre-industrial levels'.

Alleviating inequality in climate policy costs : An integrated perspective on mitigation, damage and adaptation

NARCIS (Netherlands)

De Cian, E.; Hof, A. F.; Marangoni, G.; Tavoni, M.; van Vuuren, Detlef

2016-01-01

Equity considerations play an important role in international climate negotiations. While policy analysis has often focused on equity as it relates to mitigation costs, there are large regional differences in adaptation costs and the level of residual damage. This paper illustrates the relevance of

Benchmark calculations on residue production within the EURISOL DS project. Part 1: thin targets

Energy Technology Data Exchange (ETDEWEB)

David, J.C.; Blideanu, V.; Boudard, A.; Dore, D.; Leray, S.; Rapp, B.; Ridikas, D.; Thiolliere, N

2006-12-15

We have begun this benchmark study using mass distribution data of reaction products obtained at GSI in inverse kinematics. This step has allowed us to make a first selection among 10 spallation models; in this way the first assessment of the quality of the models was obtained. Then, in a second part, experimental mass distributions for some elements, which either are interesting as radioactive ion beams or important due to the safety and radioprotection issues (alpha or gamma emitters), will be also compared to model calculations. These data have been obtained for an equivalent 0.8 or 1.0 GeV proton beam, which is approximately the proposed projectile energy. We note that in realistic thick targets the proton beam will be slowed down and some secondary particles will be produced. Therefore, the residual nuclei production at lower energies is also important. For this reason, we also performed in the third part of this work some excitation function calculations and the associated data obtained with gamma-spectroscopy to test the models in a wide projectile energy range. We conclude that INCL4/Abla and Isabel/Abla are the best model combinations which we recommend. We also note that the agreement between model and data are better with 1 GeV protons than with 100-200 MeV protons.

Damage of actively cooled plasma facing components of magnetic confinement controlled fusion machines

Energy Technology Data Exchange (ETDEWEB)

Chevet, G. [Association Euratom-CEA, DSM/DRFC, CEA Cadarache, Saint-Paul-Lez-Durance (France)], E-mail: gaelle.chevet@cea.fr; Schlosser, J. [Association Euratom-CEA, DSM/DRFC, CEA Cadarache, Saint-Paul-Lez-Durance (France); Martin, E.; Herb, V.; Camus, G. [Universite Bordeaux 1, UMR 5801 (CNRS-SAFRAN-CEA-UB1), Laboratoire des Composites Thermostructuraux, F-33600 Pessac (France)

2009-03-31

Plasma facing components (PFCs) of magnetic fusion machines have high manufactured residual stresses and have to withstand important stress ranges during operation. These actively cooled PFCs have a carbon fibre composite (CFC) armour and a copper alloy heat sink. Cracks mainly appear in the CFC near the composite/copper interface. In order to analyse damage mechanisms, it is important to well simulate the damage mechanisms both of the CFC and the CFC/Cu interface. This study focuses on the mechanical behaviour of the N11 material for which the scalar ONERA damage model was used. The damage parameters of this model were identified by similarity to a neighbour material, which was extensively analysed, according to the few characterization test results available for the N11. The finite elements calculations predict a high level of damage of the CFC at the interface zone explaining the encountered difficulties in the PFCs fabrication. These results suggest that the damage state of the CFC cells is correlated with a conductivity decrease to explain the temperature increase of the armour surface under fatigue heat load.

Damage of actively cooled plasma facing components of magnetic confinement controlled fusion machines

Science.gov (United States)

Chevet, G.; Schlosser, J.; Martin, E.; Herb, V.; Camus, G.

2009-03-01

Plasma facing components (PFCs) of magnetic fusion machines have high manufactured residual stresses and have to withstand important stress ranges during operation. These actively cooled PFCs have a carbon fibre composite (CFC) armour and a copper alloy heat sink. Cracks mainly appear in the CFC near the composite/copper interface. In order to analyse damage mechanisms, it is important to well simulate the damage mechanisms both of the CFC and the CFC/Cu interface. This study focuses on the mechanical behaviour of the N11 material for which the scalar ONERA damage model was used. The damage parameters of this model were identified by similarity to a neighbour material, which was extensively analysed, according to the few characterization test results available for the N11. The finite elements calculations predict a high level of damage of the CFC at the interface zone explaining the encountered difficulties in the PFCs fabrication. These results suggest that the damage state of the CFC cells is correlated with a conductivity decrease to explain the temperature increase of the armour surface under fatigue heat load.

Damage of actively cooled plasma facing components of magnetic confinement controlled fusion machines

International Nuclear Information System (INIS)

Chevet, G.; Schlosser, J.; Martin, E.; Herb, V.; Camus, G.

2009-01-01

Plasma facing components (PFCs) of magnetic fusion machines have high manufactured residual stresses and have to withstand important stress ranges during operation. These actively cooled PFCs have a carbon fibre composite (CFC) armour and a copper alloy heat sink. Cracks mainly appear in the CFC near the composite/copper interface. In order to analyse damage mechanisms, it is important to well simulate the damage mechanisms both of the CFC and the CFC/Cu interface. This study focuses on the mechanical behaviour of the N11 material for which the scalar ONERA damage model was used. The damage parameters of this model were identified by similarity to a neighbour material, which was extensively analysed, according to the few characterization test results available for the N11. The finite elements calculations predict a high level of damage of the CFC at the interface zone explaining the encountered difficulties in the PFCs fabrication. These results suggest that the damage state of the CFC cells is correlated with a conductivity decrease to explain the temperature increase of the armour surface under fatigue heat load

Acoustic Emission Monitoring of Lightning-Damaged CFRP Laminates during Compression-after-Impact Test

Energy Technology Data Exchange (ETDEWEB)

Kwon, Oh Yang; Shin, Jae Ha [Department of Mechanical Engineering, Inha University, Incheon (Korea, Republic of)

2012-06-15

Carbon-fiber reinforced plastic(CFRP) laminates made of nano-particle-coated carbon fibers and damaged by a simulated lightning strike were tested under compression-after-impact(CAI) mode, during which the damage progress due to compressive loading has been monitored by acoustic emission(AE). The impact damage was induced not by mechanical loading but by a simulated lightning strike. Conductive nano-particles were coated directly on the fibers, from which CFRP coupons were made. The coupon were subjected to the strikes with a high voltage/current impulse of 10-40 kA within a few . The effects of nano-particle coating and the degree of damage induced by the simulated lightning strikes on AE activities were examined, and the relationship between the compressive residual strength and AE behavior has been evaluated in terms of AE event counts and the onset of AE activity with the compressive loading. The degree of impact damage was also measured in terms of damage area by using ultrasonic C-scan images. The assessment during the CAI tests of damaged CFRP showed that AE monitoring appeared to be useful to differentiate the degree of damage hence the mechanical integrity of composite structures damaged by lightning strikes.

Harvest operations for density management: planning requirements, production, costs, stand damage, and recommendations

Science.gov (United States)

Loren D. Kellogg; Stephen J. Pilkerton

2013-01-01

Since the early 1990s, several studies have been undertaken to determine the planning requirements, productivity, costs, and residual stand damage of harvest operations in thinning treatments designed to promote development of complex forest structure in order to enhance ecological functioning and biological diversity. Th ese studies include the Oregon State...

Analysis of radiation damaged nanocrystals

International Nuclear Information System (INIS)

Sitek, J.; Dekan, J.; Sedlackova, K.; Sagatova, A.

2014-01-01

Ribbon-shaped specimens of the master alloy were prepared by planar flow casting. The ribbons with nominal composition of (Fe_1_-_xN_x)_8_1Nb_7B_1_2 (x = 0, 0.25, 0.5, 0.75) were about 25 μm thick and 10 mm wide. To achieve nanocrystalline state, the amorphous ribbons were annealed in vacuum at the temperature of 550 grad C for 1 hour. Samples were irradiated by neutrons in nuclear reactor with fluence of 10"1"6 n/cm"2 and 10"1"7 n/cm"2. and by electrons in linear accelerator with dose 1 MGy at the Slovak Medical University. Moessbauer spectra were collected in transmission geometry by a conventional constant-acceleration spectrometer with a "5"7Co(Rh) source. All spectra were measured at room temperature and evaluated by the CONFIT program, which allows simultaneous treatment of crystalline and residual amorphous phase by means of individual lines and distribution of hyperfine components. After summarizing all obtained results, the fluence 10"1"6 n/cm"2 is still not sufficiently high significantly damage amorphous and crystalline structure. This fluence more or less modify the structure than damage. After fluence 10"17"n/cm"2 we observed beginning of the. structural damage. Our results show, that high electron dose also modify the structure of nanocrystaline alloys. In further study of this alloy it would be necessary to find the limit of electron dose under that the alloy is resistant against electron's damage. From point of view Moessbauer spectroscopy the most sensitive parameter is direction of net magnetic moment. (authors)

Analysis of lifetime and residual strength of wood

DEFF Research Database (Denmark)

Nielsen, Lauge Fuglsang

1997-01-01

The present paper is thought of as a working paper for the CTBA-seminar on Thematic network in the field for reliability based design of timber structures, Topic: Numerical methods for structural analysis. It is preliminary and quite informal in its structure. The intention is to present some wood...... technological problems which can be solved with respect to lifetime and residual strength by the so-called DVM-theory (Damaged Viscoelastic Material). The outlines of the paper is straight on: Expressions are presented by which the analysis is made. then some examples are considered with solutions presented...

Collimator system for the stabilization of the dynamical residual-gas pressure in the heavy-ion synchrotron SIS18; Kollimatorsystem zur Stabilisierung des dynamischen Restgasdruckes im Schwerionensynchrotron SIS18

Energy Technology Data Exchange (ETDEWEB)

Omet, Carsten

2009-01-15

In order to achieve higher beam intensities of heavy ion beams in ring accelerators, low charge state ions can be used. By lowering the charge state, the space charge limit is shifted to higher particle numbers and stripping losses can be avoided. During test operation of the SIS18 at GSI with high intensity low charge state heavy ion beams, strong intensity dependent beam losses have been observed. It was found that these beam losses are originated to a large extent by the change of charge state of the circulating ions during collisions with residual gas atoms. The resulting deviation of m/q relative to the reference ion leads, in combination with dispersive elements in the ion optic lattice, to a modified trajectory, followed by the loss of the ion on the beam pipe. At the impact position, loosely bound residual gas molecules are released by ion stimulated desorption which increases the residual gas pressure locally. This pressure rise itself enhances the charge exchange rate, which can develop into a self amplifying process of pressure rise and subsequent beam loss. A method for the stabilization of the dynamic residual gas pressure is the use of special catcher systems, which minimize the production of desorption gases and remove them by strong pumping. Therefore, the pressure on the beam axis should remain as stable as possible. Other processes, e.g. Coulomb scattering of the beam ions by residual gas particles and unavoidable systematic beam losses can increase the gas pressure additionally. The pressure in the accelerator is further subjected to ionization of the residual gas atoms themselves, thermal out gassing of the beam pipes, insertions and pumps. In this work, a detailed numerical model of the interplay between the residual gas pressure dynamics in the accelerator, possible stabilization measures, e.g. by catchers and the resulting beam life time has been developed. The forecasted beam life times and pressures are verified by machine experiments, as

Residual stresses

International Nuclear Information System (INIS)

Sahotra, I.M.

2006-01-01

The principal effect of unloading a material strained into the plastic range is to create a permanent set (plastic deformation), which if restricted somehow, gives rise to a system of self-balancing within the same member or reaction balanced by other members of the structure., known as residual stresses. These stresses stay there as locked-in stresses, in the body or a part of it in the absence of any external loading. Residual stresses are induced during hot-rolling and welding differential cooling, cold-forming and extruding: cold straightening and spot heating, fabrication and forced fitting of components constraining the structure to a particular geometry. The areas which cool more quickly develop residual compressive stresses, while the slower cooling areas develop residual tensile stresses, and a self-balancing or reaction balanced system of residual stresses is formed. The phenomenon of residual stresses is the most challenging in its application in surface modification techniques determining endurance mechanism against fracture and fatigue failures. This paper discusses the mechanism of residual stresses, that how the residual stresses are fanned and what their behavior is under the action of external forces. Such as in the case of a circular bar under limit torque, rectangular beam under limt moment, reclaiming of shafts welds and peening etc. (author)

A procedure for evaluating residual life of major components in light water reactors

International Nuclear Information System (INIS)

Uchida, S.; Fujimori, H.; Ibe, E.; Kuniya, J.; Hayashi, M.; Fuse, M.; Yamauchi, K.

1995-01-01

A computer program for evaluating residual life of major components in boiling water reactors is proposed. It divides the stress corrosion cracking process into two stages; a probabilistic crack generation stage and a deterministic crack propagation one. The minimum period of the crack generation stage is evaluated assuming an exponential distribution of the stage. The crack propagation rate is calculated by the slip-dissolution/film-rupture model. The neutron flux and fluence dependence of the neutron radiation effects on material properties was evaluated by using theoretical models of radiation damage. The computer program works on an engineering work station. Evaluated results are displayed as a map of the residual life, or as graphs of crack length evolution

DNA Damage Induction and Repair Evaluated in Human Lymphocytes Irradiated with X-Rays an Neutrons

International Nuclear Information System (INIS)

Niedzwiedz, W.; Cebulska-Wasilewska, A.

2000-12-01

The objective of this study was to evaluate the kinetic of the DNA damage induction and their subsequent repair in human lymphocytes exposed to various types of radiation. PBLs cells were isolated from the whole blood of two young healthy male subjects and one skin cancer patient, and than exposed to various doses of low LET X-rays and high LET neutrons from 252 Cf source. To evaluate the DNA damage we have applied the single cell get electrophoresis technique (SCGE) also known as the comet assay. In order to estimate the repair efficiency, cells, which had been irradiated with a certain dose, were incubated at 37 o C for various periods of time (0 to 60 min). The kinetic of DNA damage recovery was investigated by an estimation of residual DNA damage persisted at cells after various times of post-irradiation incubation (5, 10, 15, 30 and 60 min). We observed an increase of the DNA damage (reported as a Tail DNA and Tail moment parameters) in linear and linear-quadratic manner, with increasing doses of X-rays and 252 Cf neutrons, respectively. Moreover, for skin cancer patient (Code 3) at whole studied dose ranges the higher level of the DNA damage was observed comparing to health subjects (Code 1 and 2), however statistically insignificant (for Tail DNA p=0.056; for Tail moment p=0.065). In case of the efficiency of the DNA damage repair it was observed that after 1 h of post-irradiation incubation the DNA damage induced with both, neutrons and X-rays had been significantly reduced (from 65% to 100 %). Furthermore, in case of skin cancer patient we observed lover repair efficiency of X-rays induced DNA damage. After irradiation with neutrons within first 30 min, the Tail DNA and Tail moment decreased of about 50%. One hour after irradiation, almost 70% of residual and new formed DNA damage was still observed. In this case, the level of unrepaired DNA damage may represent the fraction of the double strand breaks as well as more complex DNA damage (i.e.-DNA or DNA

Swift heavy ion induced modification of aliphatic polymers

Energy Technology Data Exchange (ETDEWEB)

Hossain, Umme Habiba

2015-01-15

In this thesis, the high energy heavy ion induced modification of aliphatic polymers is studied. Two polymer groups, namely polyvinyl polymers (PVF, PVAc, PVA and PMMA) and fluoropolymers (PVDF, ETFE, PFA and FEP) were used in this work. Polyvinyl polymers were investigated since they will be used as insulating materials in the superconducting magnets of the new ion accelerators of the planned International Facility for Antiproton and Ion Research (FAIR) at the GSI Helmholtz-Centre of Heavy Ion Research (GSI) in Darmstadt. In order to study ion-beam induced degradation, all polymer foils were irradiated at the GSI linear accelerator UNILAC using several projectiles (U, Au, Sm, Xe) and experimentation sites (beam lines X0 and M3) over a large fluence regime (1 x 10{sup 10} - 5 x 10{sup 12} ions/cm{sup 2}). Five independent techniques, namely infrared (FT-IR) and ultraviolet-visible (UV-Vis) spectroscopy, residual gas analysis (RGA), thermal gravimetric analysis (TGA), and mass loss analysis (ML), were used to analyze the irradiated samples. FT-IR spectroscopy revealed that ion irradiation led to the decrease of characteristic band intensities showing the general degradation of the polymers, with scission of side groups and the main backbone. As a consequence of the structural modification, new bands appeared. UV-Vis transmission analysis showed an absorption edge shift from the ultraviolet region towards the visible region indicating double bond and conjugated double bond formation. On-line massspectrometric residual gas analysis showed the release of small gaseous fragment molecules. TGA analysis gave evidence of a changed thermal stability. With ML analysis, the considerable mass loss was quantified. The results of the five complementary analytical methods show how heavy ion irradiation changes the molecular structure of the polymers. Molecular degradation mechanisms are postulated. The amount of radiation damage is found to be sensitive to the used type of ionic

1.06 μm 150 psec laser damage study of diamond turned, diamond turned/polished and polished metal mirrors

International Nuclear Information System (INIS)

Saito, T.T.; Milam, D.; Baker, P.; Murphy, G.

1975-01-01

Using a well characterized 1.06 μm 150 ps glass laser pulse the damage characteristics for diamond turned, diamond turned/ polished, and polished copper and silver mirrors less than 5 cm diameter were studied. Although most samples were tested with a normal angle of incidence, some were tested at 45 0 with different linear polarization showing an increase in damage threshold for S polarization. Different damage mechanisms observed will be discussed. Laser damage is related to residual surface influences of the fabrication process. First attempts to polish diamond turned surfaces resulted in a significant decrease in laser damage threshold. The importance of including the heat of fusion in the one dimensional heat analysis of the theoretical damage threshold and how close the samples came to the theoretical damage threshold is discussed. (auth)

Residual coal exploitation and its impact on sustainable development of the coal industry in China

International Nuclear Information System (INIS)

Zhang, Yujiang; Feng, Guorui; Zhang, Min; Ren, Hongrui; Bai, Jinwen; Guo, Yuxia; Jiang, Haina; Kang, Lixun

2016-01-01

Although China owns large coal reserves, it now faces the problem of depletion of its coal resources in advance. The coal-based energy mix in China will not change in the short term, and a means of delaying the coal resources depletion is therefore urgently required. The residual coal was exploited first with a lower recovery percentage and was evaluated as commercially valuable damaged coal. This approach is in comparison to past evaluations when the residual coal was allocated as exploitation losses. Coal recovery rates, the calculation method of residual coal reserves and statistics of its mines in China were given. On this basis, a discussion concerning the impacts on the delay of China's coal depletion, development of coal exploitation and sustainable developments, as well as technologies and relevant policies, were presented. It is considered that the exploitation of residual coal can effectively delay China's coal depletion, inhibit the construction of new mines, redress the imbalance between supply and demand of coal in eastern China, improve the mining area environment and guarantee social stability. The Chinese government supports the exploitation technologies of residual coal. Hence, exploiting residual coal is of considerable importance in sustainable development of the coal industry in China. - Highlights: •Pay attention to residual coal under changing energy-mix environment in China. •Estimate residual coal reserves and investigate its exploitation mines. •Discuss impacts of residual coal exploitation on delay of coal depletion in China. •Discuss impacts on coal mining industry and residual coal exploitation technology. •Give corresponding policy prescriptions.

A Two-Stage Method for Structural Damage Prognosis in Shear Frames Based on Story Displacement Index and Modal Residual Force

Directory of Open Access Journals (Sweden)

Asghar Rasouli

2015-01-01

Full Text Available A two-stage method is proposed to properly identify the location and the extent of damage in shear frames. In the first stage, a story displacement index (SDI is presented to precisely locate the damage in the shear frame which is calculated using the modal analysis information of the damaged structure. In the second stage, by defining a new objective function, the extent of the actual damage is determined via an imperialist competitive algorithm. The performance of the proposed method is demonstrated by implementing the technique to three examples containing five-, ten-, and twenty-five-story shear frames with noises and without them in modal data. Moreover, the performance of the proposed method has been verified through using a benchmark problem. Numerical results show the high efficiency of the proposed method for accurately identifying the location and the extent of structural damage in shear frames.

Residual stresses

International Nuclear Information System (INIS)

Macherauch, E.

1978-01-01

Residual stresses are stresses which exist in a material without the influence of external powers and moments. They come into existence when the volume of a material constantly changes its form as a consequence of mechanical, thermal, and/or chemical processes and is hindered by neighbouring volumes. Bodies with residual stress are in mechanical balance. These residual stresses can be manifested by means of all mechanical interventions disturbing this balance. Acoustical, optical, radiological, and magnetical methods involving material changes caused by residual stress can also serve for determining residual stress. Residual stresses have an ambivalent character. In technical practice, they are feared and liked at the same time. They cause trouble because they can be the cause for unexpected behaviour of construction elements. They are feared since they can cause failure, in the worst case with catastrophical consequences. They are appreciated, on the other hand, because, in many cases, they can contribute to improvements of the material behaviour under certain circumstances. But they are especially liked for their giving convenient and (this is most important) mostly uncontrollable explanations. For only in very few cases we have enough knowledge and possibilities for the objective evaluation of residual stresses. (orig.) [de

The effects of machine parameters on residual stress determined using micro-Raman spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Sparks, R.G.; Enloe, W.S.; Paesler, M.A.

1988-12-01

The effects of machine parameters on residual stresses in single point diamond turned silicon and germanium have been investigated using micro-Raman spectroscopy. Residual stresses were sampled across ductile feed cuts in < 100 > silicon and germanium which were single point diamond turned using a variety of feed rates, rake angles and clearance angles. High spatial resolution micro-Raman spectra (1{mu}m spot) were obtained in regions of ductile cutting where no visible surface damage was present. The use of both 514-5nm and 488.0nm excitation wavelengths, by virtue of their differing characteristic penetration depths in the materials, allowed determinations of stress profiles as a function of depth into the sample. Previous discussions have demonstrated that such Raman spectra will exhibit asymmetrically broadened peaks which are characteristic of the superposition of a continuum of Raman scatterers from the various depths probed. Depth profiles of residual stress were obtained using computer deconvolution of the resulting asymmetrically broadened raman spectra.

Determined analysis of safety, viability and residual service life on criteria of crack mechanics

International Nuclear Information System (INIS)

Matvienko, Yu.G.

1997-01-01

Unified methods used in analysis of reliability, vulnerability, and residual lifetime of equipment with crack damage are considered, an increase in the desired lifetime is proven in the framework of vulnerability concept that allows crack developing with regard to the given level of reliability. The problem of reliability, vulnerability, and the lifetime is shown to be an interrelated problem. Optimal combination of the strength value, plasticity and resistance to crack developing results from the criteria of reliability and vulnerability based, in turn, on the principles of the mechanics of cracks. Structural features of technical systems can hinder the crack developing and prevent drastic damages of the equipment thus increasing the lifetime

Measures of total stress-induced blood pressure responses are associated with vascular damage.

Science.gov (United States)

Nazzaro, Pietro; Seccia, Teresa; Vulpis, Vito; Schirosi, Gabriella; Serio, Gabriella; Battista, Loredana; Pirrelli, Anna

2005-09-01

The role of cardiovascular reactivity to study hypertension, and the assessment methods, are still controversial. We aimed to verify the association of hypertension and vascular damage with several measures of cardiovascular response. We studied 40 patients with normal-high (132 +/- 1/87 +/- 1 mm Hg) blood pressure (Group 1) and 80 untreated hypertensive subjects. Postischemic forearm vascular resistance (mFVR) served to differentiate hypertensive subjects (142 +/- 2/92 +/- 1 mm Hg v 143 +/- 2/94 +/- 2 mm Hg, P = NS) with a lower (Group 2) and higher (Group 3) hemodynamic index of vascular damage (4.8 +/- .05 v 6.3 +/- .09, P blood pressure, heart rate, forearm blood flow, and vascular resistance. Reactivity measures included: a) change from baseline, b) residualized score, c) cumulative change from baseline and residualized score, and d) total reactivity as area-under-the-curve (AUC), including changes occurring during baseline and recovery phases. The AUC of systolic blood pressure, diastolic blood pressure, and mFVR progressively increased in the groups (P AUC of SBP, DBP, and forearm blood flow and resistance demonstrated the highest (P AUC of SBP (beta = 0.634) and forearm blood flow (beta = -0.337) were predictive (P blood pressure stress response, as AUC, including baseline and recovery phases, was significantly better associated with hypertension and vascular damage than the other reactivity measures studied.

Evaluation of residue-residue contact predictions in CASP9

KAUST Repository

Monastyrskyy, Bohdan

2011-01-01

This work presents the results of the assessment of the intramolecular residue-residue contact predictions submitted to CASP9. The methodology for the assessment does not differ from that used in previous CASPs, with two basic evaluation measures being the precision in recognizing contacts and the difference between the distribution of distances in the subset of predicted contact pairs versus all pairs of residues in the structure. The emphasis is placed on the prediction of long-range contacts (i.e., contacts between residues separated by at least 24 residues along sequence) in target proteins that cannot be easily modeled by homology. Although there is considerable activity in the field, the current analysis reports no discernable progress since CASP8.

Interactive effects of rice residue and water stress on growth and metabolism of wheat seedlings

Directory of Open Access Journals (Sweden)

Nimisha Amist

2014-08-01

Full Text Available In the present study effects of rice residue with and without water stress were studied on Triticum aestivum L. cv. Shatabadi. The mixture of residue and garden soil in 1:1 ratio was considered as 50% (R1 and only decomposed residue as 100% (R2. Garden soil was taken as control. Twenty five seeds were sown in each experimental trays filled with soil mixture according to the treatments. Trays were arranged in two groups. After 15 days one set was subjected to water stress (WS by withholding water supply for 3 days. Morphological and biochemical parameters of 18 days old seedlings were recorded. Seedling height decreased in all treatments. A gradual decrease in relative water content, pigment and protein contents of wheat seedlings were observed. Sugar and proline contents increased in treatments. An increase in malondialdehyde (MDA content and antioxidative enzyme activities was recorded. Elevation in catalase activity was observed in all treatments except in plants with water deficit. Ascorbate peroxidase (APX and guaiacol peroxidase (GPX activities increased when residue mixed with soil but decreased in seedlings under the combined influence of the residue and water stress. Higher amount of MDA and lower activities of APX and GPX reflected the oxidative damage in seedlings under combined treatments. Rice residue inhibited growth of wheat seedlings. Water stress intensified the effects of residue.

Thermal healing of the sub-surface damage layer in sapphire

International Nuclear Information System (INIS)

Pinkas, Malki; Lotem, Haim; Golan, Yuval; Einav, Yeheskel; Golan, Roxana; Chakotay, Elad; Haim, Avivit; Sinai, Ela; Vaknin, Moshe; Hershkovitz, Yasmin; Horowitz, Atara

2010-01-01

The sub-surface damage layer formed by mechanical polishing of sapphire is known to reduce the mechanical strength of the processed sapphire and to degrade the performance of sapphire based components. Thermal annealing is one of the methods to eliminate the sub-surface damage layer. This study focuses on the mechanism of thermal healing by studying its effect on surface topography of a- and c-plane surfaces, on the residual stresses in surface layers and on the thickness of the sub-surface damage layer. An atomically flat surface was developed on thermally annealed c-plane surfaces while a faceted roof-top topography was formed on a-plane surfaces. The annealing resulted in an improved crystallographic perfection close to the sample surface as was indicated by a noticeable decrease in X-ray rocking curve peak width. Etching experiments and surface roughness measurements using white light interferometry with sub-nanometer resolution on specimens annealed to different extents indicate that the sub-surface damage layer of the optically polished sapphire is less than 3 μm thick and it is totally healed after thermal treatment at 1450 deg. C for 72 h.

RESIDUAL STRENGTH AND ENDURANCE OF ROD CONSTRUCTION ELEMENTS OF AIRCRAFT AFTER THE DAMAGE BY LIGHTNING-LIKE ELECTRICAL DISCHARGES

Directory of Open Access Journals (Sweden)

2015-01-01

Full Text Available Caused by lightning damage to the external elements of construction of the aircraft, in the form of deformities, burn-through and erosive craters and also hidden defects in the affected area can cause a reduction in the strength of damaged parts. Fatigue tests of samples of rod construction elements damaged by lightning-like electrical discharges showed that for a symmetric cycle of variable loading at an amplitude of 100 kPa and a frequency of 50 Hz supply of fatigue strength decreased in 1,5-1,7 times, and fatigue life decreased in 25 times at local burns and in 70 times at annular burns. The main reason is education on the details of micro cracks in the area of erosive craters formed by discharge.

Orientation and the extent of exfoliation of clay on scratch damage in polyamide 6 nanocomposites

International Nuclear Information System (INIS)

Dasari, Aravind; Yu Zhongzhen; Mai Yiuwing; Kim, Jang-Kyo

2008-01-01

The major objectives of this work are to understand the effects of organoclay, its extent of exfoliation and orientation, and indenter geometry on the scratch characteristics of polyamide 6/organoclay nanocomposites. Two different organically treated clays are used for this purpose and their structural parameters in a polyamide 6 matrix quantified. It is shown that, while the material properties are important for scratching resistance, they are not the only determinants of the scratch performance of materials. Further, despite proving beneficial to scratch resistance, in terms of residual depth, the presence (and exfoliation) of organoclay promotes the formation of brittle cracks during scratching. But with no organoclay layers, plastic flow controls the scratch damage in neat polyamide 6 with large residual depths. Factors such as orientation of clay layers and variations of indenter tip geometry also exert dominant effects on scratch penetration resistance and damage. Additionally, significant plastic flow and rotation of organoclay layers from the original configuration are observed underneath the sliding indenter

Effects of face sheet damage on residual strength of GRP sandwich panels in naval ships

DEFF Research Database (Denmark)

Hayman, Brian; Echtermeyer, Andreas T.; Berggreen, Christian

2010-01-01

is represented by machined cracks and circular holes in the face laminates. Tests have been performed on laminate specimens with and without circular holes under tensile loading and on sandwich face sheets with holes, cracks and real impact damage under compressive loading. The results are compared...

X-ray spectroscopy of warm and hot electron components in the CAPRICE source plasma at EIS testbench at GSI

Energy Technology Data Exchange (ETDEWEB)

Mascali, D., E-mail: davidmascali@lns.infn.it; Celona, L.; Castro, G.; Torrisi, G.; Neri, L.; Gammino, S.; Ciavola, G. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali del Sud, – Via S. Sofia 62, 95123 Catania (Italy); Maimone, F.; Maeder, J.; Tinschert, K.; Spaedtke, K. P.; Rossbach, J.; Lang, R. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Planckstrasse 1, 64291 Darmstadt (Germany); Romano, F. P. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali del Sud, – Via S. Sofia 62, 95123 Catania (Italy); IBAM, CNR, Via Biblioteca 4, 95124 Catania (Italy); Musumarra, A.; Altana, C.; Caliri, C. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali del Sud, – Via S. Sofia 62, 95123 Catania (Italy); Dipartimento di Fisica e Astronomia, Università degli Studi di Catania, via S. Sofia 64, 95123 Catania (Italy)

2014-02-15

An experimental campaign aiming to detect X radiation emitted by the plasma of the CAPRICE source – operating at GSI, Darmstadt – has been carried out. Two different detectors (a SDD – Silicon Drift Detector and a HpGe – hyper-pure Germanium detector) have been used to characterize the warm (2–30 keV) and hot (30–500 keV) electrons in the plasma, collecting the emission intensity and the energy spectra for different pumping wave frequencies and then correlating them with the CSD of the extracted beam measured by means of a bending magnet. A plasma emissivity model has been used to extract the plasma density along the cone of sight of the SDD and HpGe detectors, which have been placed beyond specific collimators developed on purpose. Results show that the tuning of the pumping frequency considerably modifies the plasma density especially in the warm electron population domain, which is the component responsible for ionization processes: a strong variation of the plasma density near axis region has been detected. Potential correlations with the charge state distribution in the plasma are explored.

Station blackout core damage frequency in an advanced nuclear reactor

International Nuclear Information System (INIS)

Carvalho, Luiz Sergio de

2004-01-01

Even though nuclear reactors are provided with protection systems so that they can be automatically shut down in the event of a station blackout, the consequences of this event can be severe. This is because many safety systems that are needed for removing residual heat from the core and for maintaining containment integrity, in the majority of the nuclear power plants, are AC dependent. In order to minimize core damage frequency, advanced reactor concepts are being developed with safety systems that use natural forces. This work shows an improvement in the safety of a small nuclear power reactor provided by a passive core residual heat removal system. Station blackout core melt frequencies, with and without this system, are both calculated. The results are also compared with available data in the literature. (author)

Polyphosphate is a key factor for cell survival after DNA damage in eukaryotic cells.

Science.gov (United States)

Bru, Samuel; Samper-Martín, Bàrbara; Quandt, Eva; Hernández-Ortega, Sara; Martínez-Laínez, Joan M; Garí, Eloi; Rafel, Marta; Torres-Torronteras, Javier; Martí, Ramón; Ribeiro, Mariana P C; Jiménez, Javier; Clotet, Josep

2017-09-01

Cells require extra amounts of dNTPs to repair DNA after damage. Polyphosphate (polyP) is an evolutionary conserved linear polymer of up to several hundred inorganic phosphate (Pi) residues that is involved in many functions, including Pi storage. In the present article, we report on findings demonstrating that polyP functions as a source of Pi when required to sustain the dNTP increment essential for DNA repair after damage. We show that mutant yeast cells without polyP produce less dNTPs upon DNA damage and that their survival is compromised. In contrast, when polyP levels are ectopically increased, yeast cells become more resistant to DNA damage. More importantly, we show that when polyP is reduced in HEK293 mammalian cell line cells and in human dermal primary fibroblasts (HDFa), these cells become more sensitive to DNA damage, suggesting that the protective role of polyP against DNA damage is evolutionary conserved. In conclusion, we present polyP as a molecule involved in resistance to DNA damage and suggest that polyP may be a putative target for new approaches in cancer treatment or prevention. Copyright © 2017 Elsevier B.V. All rights reserved.

Carbohydrate Mimetic Peptides Augment Carbohydrate-Reactive Immune Responses in the Absence of Immune Pathology

International Nuclear Information System (INIS)

Hennings, Leah; Artaud, Cecile; Jousheghany, Fariba; Monzavi-Karbassi, Behjatolah; Pashov, Anastas; Kieber-Emmons, Thomas

2011-01-01

Among the most challenging of clinical targets for cancer immunotherapy are Tumor Associated Carbohydrate Antigens (TACAs). To augment immune responses to TACA we are developing carbohydrate mimetic peptides (CMPs) that are sufficiently potent to activate broad-spectrum anti-tumor reactivity. However, the activation of immune responses against terminal mono- and disaccharide constituents of TACA raises concerns regarding the balance between “tumor destruction” and “tissue damage”, as mono- and disaccharides are also expressed on normal tissue. To support the development of CMPs for clinical trial testing, we demonstrate in preclinical safety assessment studies in mice that vaccination with CMPs can enhance responses to TACAs without mediating tissue damage to normal cells expressing TACA. BALB/c mice were immunized with CMPs that mimic TACAs reactive with Griffonia simplicifolia lectin 1 (GS-I), and tissue reactivity of serum antibodies were compared with the tissue staining profile of GS-I. Tissues from CMP immunized mice were analyzed using hematoxylin and eosin stain, and Luxol-fast blue staining for myelination. Western blots of membranes from murine mammary 4T1 cells, syngeneic with BALB/c mice, were also compared using GS-I, immunized serum antibodies, and naive serum antibodies. CMP immunization enhanced glycan reactivities with no evidence of pathological autoimmunity in any immunized mice demonstrating that tissue damage is not an inevitable consequence of TACA reactive responses

Carbohydrate Mimetic Peptides Augment Carbohydrate-Reactive Immune Responses in the Absence of Immune Pathology

Energy Technology Data Exchange (ETDEWEB)

Hennings, Leah; Artaud, Cecile; Jousheghany, Fariba; Monzavi-Karbassi, Behjatolah; Pashov, Anastas; Kieber-Emmons, Thomas, E-mail: tke@uams.edu [Winthrop P. Rockefeller Cancer Institute and Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205 (United States)

2011-11-11

Among the most challenging of clinical targets for cancer immunotherapy are Tumor Associated Carbohydrate Antigens (TACAs). To augment immune responses to TACA we are developing carbohydrate mimetic peptides (CMPs) that are sufficiently potent to activate broad-spectrum anti-tumor reactivity. However, the activation of immune responses against terminal mono- and disaccharide constituents of TACA raises concerns regarding the balance between “tumor destruction” and “tissue damage”, as mono- and disaccharides are also expressed on normal tissue. To support the development of CMPs for clinical trial testing, we demonstrate in preclinical safety assessment studies in mice that vaccination with CMPs can enhance responses to TACAs without mediating tissue damage to normal cells expressing TACA. BALB/c mice were immunized with CMPs that mimic TACAs reactive with Griffonia simplicifolia lectin 1 (GS-I), and tissue reactivity of serum antibodies were compared with the tissue staining profile of GS-I. Tissues from CMP immunized mice were analyzed using hematoxylin and eosin stain, and Luxol-fast blue staining for myelination. Western blots of membranes from murine mammary 4T1 cells, syngeneic with BALB/c mice, were also compared using GS-I, immunized serum antibodies, and naive serum antibodies. CMP immunization enhanced glycan reactivities with no evidence of pathological autoimmunity in any immunized mice demonstrating that tissue damage is not an inevitable consequence of TACA reactive responses.

Cumulative damage and estimation of residual life in metallic alloys under creep

International Nuclear Information System (INIS)

Silveira, T.L. da.

1980-07-01

The mechanical behavior and fracture characteristics have been determined for a group of materials tested under conditions of creep, and the ability of various models detailed in the literature to describe these observed characteristics discussed. The parametric methods employed in formulating the indices which define the allowable stresses for design codes have been analysed, and a method of Minimum Standard Deviation (MSD) for construction of reference curves has been proposed. The constitutive equations used in the methods of analysis of creep stresses have been discussed. Finally, the accumulated damage by creep in a particular structure which had been in extended service has been characterized and, based on these observations, the methods for estimation of remaining life in industrial equipment have been analysed. (Author) [pt

Residual stress relief due to fatigue in tetragonal lead zirconate titanate ceramics

International Nuclear Information System (INIS)

Hall, D. A.; Mori, T.; Comyn, T. P.; Ringgaard, E.; Wright, J. P.

2013-01-01

High energy synchrotron XRD was employed to determine the lattice strain ε{111}and diffraction peak intensity ratio R{200}in tetragonal PZT ceramics, both in the virgin poled state and after a bipolar fatigue experiment. It was shown that the occurrence of microstructural damage during fatigue was accompanied by a reduction in the gradient of the ε{111}–cos 2 ψ plot, indicating a reduction in the level of residual stress due to poling. In contrast, the fraction of oriented 90° ferroelectric domains, quantified in terms of R{200}, was not affected significantly by fatigue. The change in residual stress due to fatigue is interpreted in terms of a change in the average elastic stiffness of the polycrystalline matrix due to the presence of inter-granular microcracks

Residual stress relief due to fatigue in tetragonal lead zirconate titanate ceramics

Science.gov (United States)

Hall, D. A.; Mori, T.; Comyn, T. P.; Ringgaard, E.; Wright, J. P.

2013-07-01

High energy synchrotron XRD was employed to determine the lattice strain ɛ{111} and diffraction peak intensity ratio R{200} in tetragonal PZT ceramics, both in the virgin poled state and after a bipolar fatigue experiment. It was shown that the occurrence of microstructural damage during fatigue was accompanied by a reduction in the gradient of the ɛ{111}-cos2 ψ plot, indicating a reduction in the level of residual stress due to poling. In contrast, the fraction of oriented 90° ferroelectric domains, quantified in terms of R{200}, was not affected significantly by fatigue. The change in residual stress due to fatigue is interpreted in terms of a change in the average elastic stiffness of the polycrystalline matrix due to the presence of inter-granular microcracks.

Eddy Current Nondestructive Residual Stress Assessment in Shot-Peened Nickel-Base Superalloys

International Nuclear Information System (INIS)

Blodgett, M.P.; Yu, F.; Nagy, P.B.

2005-01-01

Shot peening and other mechanical surface enhancement methods improve the fatigue resistance and foreign-object damage tolerance of metallic components by introducing beneficial near-surface compressive residual stresses and hardening the surface. However, the fatigue life improvement gained via surface enhancement is not explicitly accounted for in current engine component life prediction models because of the lack of accurate and reliable nondestructive methods that could verify the presence of compressive near-surface residual stresses in shot-peened hardware. In light of its frequency-dependent penetration depth, the measurement of eddy current conductivity has been suggested as a possible means to allow the nondestructive evaluation of subsurface residual stresses in surface-treated components. This technique is based on the so-called piezoresistivity effect, i.e., the stress-dependence of electrical resistivity. We found that, in contrast with most other materials, surface-treated nickel-base superalloys exhibit an apparent increase in electrical conductivity at increasing inspection frequencies, i.e., at decreasing penetration depths. Experimental results are presented to illustrate that the excess frequency-dependent apparent eddy current conductivity of shot-peened nickel-base superalloys can be used to estimate the absolute level and penetration depth of the compressive residual stress layer both before and after partial thermal relaxation

Evaluation of precipitation forecasts from 3D-Var and hybrid GSI-based system during Indian summer monsoon 2015

Science.gov (United States)

Singh, Sanjeev Kumar; Prasad, V. S.

2018-02-01

This paper presents a systematic investigation of medium-range rainfall forecasts from two versions of the National Centre for Medium Range Weather Forecasting (NCMRWF)-Global Forecast System based on three-dimensional variational (3D-Var) and hybrid analysis system namely, NGFS and HNGFS, respectively, during Indian summer monsoon (June-September) 2015. The NGFS uses gridpoint statistical interpolation (GSI) 3D-Var data assimilation system, whereas HNGFS uses hybrid 3D ensemble-variational scheme. The analysis includes the evaluation of rainfall fields and comparisons of rainfall using statistical score such as mean precipitation, bias, correlation coefficient, root mean square error and forecast improvement factor. In addition to these, categorical scores like Peirce skill score and bias score are also computed to describe particular aspects of forecasts performance. The comparison results of mean precipitation reveal that both the versions of model produced similar large-scale feature of Indian summer monsoon rainfall for day-1 through day-5 forecasts. The inclusion of fully flow-dependent background error covariance significantly improved the wet biases in HNGFS over the Indian Ocean. The forecast improvement factor and Peirce skill score in the HNGFS have also found better than NGFS for day-1 through day-5 forecasts.

Serum levels of advanced glycation endproducts and other markers of protein damage in early diabetic nephropathy in type 1 diabetes.

Directory of Open Access Journals (Sweden)

Bruce A Perkins

Full Text Available To determine the role of markers of plasma protein damage by glycation, oxidation and nitration in microalbuminuria onset or subsequent decline of glomerular filtration rate (termed "early GFR decline" in patients with type 1 diabetes.From the 1(st Joslin Kidney Study, we selected 30 patients with longstanding normoalbuminuria and 55 patients with new onset microalbuminuria. Patients with microalbuminuria had 8-12 years follow-up during which 33 had stable GFR and 22 early GFR decline. Mean baseline GFR(CYSTATIN C was similar between the three groups. Glycation, oxidation and nitration markers were measured in protein and ultrafiltrate at baseline by liquid chromatography-tandem mass spectrometry using the most reliable methods currently available.Though none were significantly different between patients with microalbuminuria with stable or early GFR decline, levels of 6 protein damage adduct residues of plasma protein and 4 related free adducts of plasma ultrafiltrate were significantly different in patients with microalbuminuria compared to normoalbuminuria controls. Three protein damage adduct residues were decreased and 3 increased in microalbuminuria while 3 free adducts were decreased and one increased in microalbuminuria. The most profound differences were of N-formylkynurenine (NFK protein adduct residue and N(ω-carboxymethylarginine (CMA free adduct in which levels were markedly lower in microalbuminuria (P<0.001 for both.Complex processes influence levels of plasma protein damage and related proteolysis product free adducts in type 1 diabetes and microalbuminuria. The effects observed point to the possibility that patients who have efficient mechanisms of disposal of damaged proteins might be at an increased risk of developing microalbuminuria but not early renal function decline. The findings support the concept that the mechanisms responsible for microalbuminuria may differ from the mechanisms involved in the initiation of early

Radiation damage prediction system using damage function

International Nuclear Information System (INIS)

Tanaka, Yoshihisa; Mori, Seiji

1979-01-01

The irradiation damage analysis system using a damage function was investigated. This irradiation damage analysis system consists of the following three processes, the unfolding of a damage function, the calculation of the neutron flux spectrum of the object of damage analysis and the estimation of irradiation effect of the object of damage analysis. The damage function is calculated by applying the SAND-2 code. The ANISN and DOT3, 5 codes are used to calculate neutron flux. The neutron radiation and the allowable time of reactor operation can be estimated based on these calculations of the damage function and neutron flux. The flow diagram of the process of analyzing irradiation damage by a damage function and the flow diagram of SAND-2 code are presented, and the analytical code for estimating damage, which is determined with a damage function and a neutron spectrum, is explained. The application of the irradiation damage analysis system using a damage function was carried out to the core support structure of a fast breeder reactor for the damage estimation and the uncertainty evaluation. The fundamental analytical conditions and the analytical model for this work are presented, then the irradiation data for SUS304, the initial estimated values of a damage function, the error analysis for a damage function and the analytical results are explained concerning the computation of a damage function for 10% total elongation. Concerning the damage estimation of FBR core support structure, the standard and lower limiting values of damage, the permissible neutron flux and the allowable years of reactor operation are presented and were evaluated. (Nakai, Y.)

Why Are Males Bad for Females? Models for the Evolution of Damaging Male Mating Behavior

NARCIS (Netherlands)

Lessells, C.M.

2005-01-01

One explanation for the cost to mating for females caused by damaging male mating behavior is that this causes the females to adaptively modify their subsequent life histories in a way that also increases male fitness. This might occur because the reduction in residual reproductive value of the

Excavation damage and organic growth in a 1.2m diameter borehole

International Nuclear Information System (INIS)

Everitt, R.A.; Gann, P.; Brown, D.A.; Boychuk, D.M.

1994-01-01

A 1.24m diameter borehole was drilled 5m into the floor of a typical drill-and-blast tunnel in unfractured granite, at AECL's Underground Research Laboratory. Three generations of excavation damage, characteristic of what may be encountered in boreholes excavated for in-hole emplacement of used fuel wastes was observed. These include: (1) damage related to the initial excavation of the room, (2) damage caused by the drilling of the borehole itself, and (3) damage due to subsequent stress-induced spalling of the borehole walls. A biofilm containing a variety of microorganisms has developed where seepage issues from the concrete-granite interface. The biota were introduced from surface water used for mining and drilling. Their growth has been stimulated by residues from blasting and drilling, which have concentrated iron and silicon by passive sorption and energy metabolism. Ferrous iron has been oxidized and precipitated as ferrihydrite/hematite to give an orange/brown colouration on the biofilm interface black. These observations, significant to the understanding and monitoring of excavation damage, highlight the importance of thorough, in situ, multi-disciplinary characterization for vault design

Investigation of the possibility of using residual heat reactor energy

Science.gov (United States)

Aminov, R. Z.; Yurin, V. E.; Bessonov, V. N.

2017-11-01

The largest contribution to the probable frequency of core damage is blackout events. The main component of the heat capacity at each reactor within a few minutes following a blackout is the heat resulting from the braking of beta-particles and the transfer of gamma-ray energy by the fission fragments and their decay products, which is known as the residual heat. The power of the residual heat changes gradually over a long period of time and for a VVER-1000 reactor is about 15-20 MW of thermal power over 72 hours. Current cooldown systems increase the cost of the basic nuclear power plants (NPP) funds without changing the amount of electricity generated. Such systems remain on standby, accelerating the aging of the equipment and accordingly reducing its reliability. The probability of system failure increases with the duration of idle time. Furthermore, the reactor residual heat energy is not used. A proposed system for cooling nuclear power plants involves the use of residual thermal power to supply the station’s own needs in emergency situations accompanied by a complete blackout. The thermal power of residual heat can be converted to electrical energy through an additional low power steam turbine. In normal mode, the additional steam turbine generates electricity, which makes it possible to ensure spare NPP and a return on the investment in the reservation system. In this work, experimental data obtained from a Balakovo NPP was analyzed to determine the admissibility of cooldown of the reactors through the 2nd circuit over a long time period, while maintaining high-level parameters for the steam generated by the steam generators.

Relation Between Residual and Hoop Stresses and Rolling Bearing Fatigue Life

Science.gov (United States)

Oswald, Fred B.; Zaretsky, Erwin V.; Poplawski, Joseph V.

2015-01-01

Rolling-element bearings operated at high speed or high vibration may require a tight interference fit between the bore of the bearing and shaft to prevent rotation of the bearing bore around the shaft and fretting damage at the interfaces. Previous work showed that the hoop stresses resulting from tight interference fits can reduce bearing lives by as much as 65 percent. Where tight interference fits are required, case-carburized steel such as AISI 9310 or M50 NiL is often used because the compressive residual stresses inhibit subsurface crack formation and the ductile core inhibits inner-ring fracture. The presence of compressive residual stress and its combination with hoop stress also modifies the Hertz stress-life relation. This paper analyzes the beneficial effect of residual stresses on rolling-element bearing fatigue life in the presence of high hoop stresses for three bearing steels. These additional stresses were superimposed on Hertzian principal stresses to calculate the inner-race maximum shearing stress and the resulting fatigue life of the bearing. The load-life exponent p and Hertz stress-life exponent n increase in the presence of compressive residual stress, which yields increased life, particularly at lower stress levels. The Zaretsky life equation is described and is shown to predict longer bearing lives and greater load- and stress-life exponents, which better predicts observed life of bearings made from vacuum-processed steel.

Instructive of chemical residues waste administration

International Nuclear Information System (INIS)

Alfaro Vargas, Ariel

2014-01-01

An instructive is established for the waste management system of chemical residues generated at the Universidad de Costa Rica, ensuring the collection, separation, transportation, reuse, recycling and final disposal. The laboratory waste management system is conditioned to the volume and type of waste generated. The respective procedures are listed in data sheets according to the corresponding model: avoid, reduce, recycle, treat, delete. The materials are identified as: expired products, materials or damaged products, substances that have lost some of the required characteristics, waste from the regular activities of the lab, unused products that now no longer used because they are considered inadequate. The chemicals reagents or hazardous are transformed into small amounts of derivatives safe products, or less hazardous, to allow for removal or to pick up a spill of these without problem [es

Residual-strength tests of L-1011 vertical fin components after 10 and 20 years of simulated flight service

Science.gov (United States)

Lopez, O. F.

1984-01-01

Part of the NASA/ACEE Program was to determine the effect of long-term durability testing on the residual strength of graphite-epoxy cover panel and spar components of the Lockheed L-1011 aircraft vertical stabilizer. The results of these residual strength tests are presented herein. The structural behavior and failure mode of both cover panel and spar components were addressed, and the test results obtained were compared with the static test results generated by Lockheed. The effect of damage on one of the spar specimens was described.

Effect of benfotiamine in podocyte damage induced by peritoneal dialysis fluid.

Science.gov (United States)

Müller-Krebs, Sandra; Nissle, Katharina; Tsobaneli, Julia; Zeier, Martin; Kihm, Lars Philipp; Kender, Zoltan; Fleming, Thomas; Nawroth, Peter Paul; Reiser, Jochen; Schwenger, Vedat

2015-01-01

In peritoneal dialysis (PD), residual renal function (RRF) fundamentally contributes to improved quality of life and patient survival. High glucose and advanced glycation end-products (AGE) contribute locally to peritoneal and systemically to renal damage. Integrity of podocyte structure and function is of special importance to preserve RRF. Benfotiamine could counteract the glucose and AGE-mediated toxicity by blocking hyperglycemia-associated podocyte damage via the pentose-phosphate pathway. A human differentiated podocyte cell line was incubated with control solution (control), 2.5% glucose solution (glucose), and 2.5% peritoneal dialysis fluid (PDF) for 48 h either ±50 μM benfotiamine. Podocyte damage and potential benefit of benfotiamine were analyzed using immunofluorescence, western blot analysis, and a functional migration assay. For quantitation, a semiquantitative score was used. When incubating podocytes with benfotiamine, glucose, and PDF-mediated damage was reduced, resulting in lower expression of AGE and intact podocin and ZO-1 localization. The reorganization of the actin cytoskeleton was restored in the presence of benfotiamine as functional podocyte motility reached control level. Decreased level of inflammation could be shown as well as reduced podocyte apoptosis. These data suggest that benfotiamine protects podocytes from glucose and PDF-mediated dysfunction and damage, in particular, with regard to cytoskeletal reorganization, motility, inflammation, and podocyte survival.

A case study on the structural assessment of fire damaged building

Science.gov (United States)

Osman, M. H.; Sarbini, N. N.; Ibrahim, I. S.; Ma, C. K.; Ismail, M.; Mohd, M. F.

2017-11-01

This paper presents a case study on the structural assessment of building damaged by fire and discussed on the site investigations and test results prior to determine the existing condition of the building. The building was on fire for about one hour before it was extinguished. In order to ascertain the integrity of the building, a visual inspection was conducted for all elements (truss, beam, column and wall), followed by non-destructive, load and material tests. The load test was conducted to determine the ability of truss to resist service load, while the material test to determine the residual strength of the material. At the end of the investigation, a structural analysis was carried out to determine the new factor of safety by considering the residual strength. The highlighted was on the truss element due to steel behaviour that is hardly been predicted. Meanwhile, reinforced concrete elements (beam, column and wall) were found externally affected and caused its strength to be considered as sufficient for further used of building. The new factor of safety is equal to 2, considered as the minimum calculated value for the truss member. Therefore, this fire damaged building was found safe and can be used for further application.

Experimental study of residual stresses in laser clad AISI P20 tool steel on pre-hardened wrought P20 substrate

International Nuclear Information System (INIS)

Chen, J.-Y.; Conlon, K.; Xue, L.; Rogge, R.

2010-01-01

Research highlights: → Laser cladding of P20 tool steel. → Residual stress analysis of laser clad P20 tool steel. → Microstructure of laser clad P20 tool steel. → Tooling Repair using laser cladding. → Stress reliving treatment of laser clad P20 tool steel. - Abstract: Laser cladding is to deposit desired material onto the surface of a base material (or substrate) with a relatively low heat input to form a metallurgically sound and dense clad. This process has been successfully applied for repairing damaged high-value tooling to reduce their through-life cost. However, laser cladding, which needs to melt a small amount of a substrate along with cladding material, inevitably introduces residual stresses in both clad and substrate. The tensile residual stresses in the clad could adversely affect mechanical performance of the substrate being deposited. This paper presents an experimental study on process-induced residual stresses in laser clad AISI P20 tool steel onto pre-hardened wrought P20 base material and the correlation with microstructures using hole-drilling and neutron diffraction methods. Combined with X-ray diffraction and scanning electron microscopic analyses, the roles of solid-state phase transformations in the clad and heat-affected zone (HAZ) of the substrate during cladding and post-cladding heat treatments on the development and controllability of residual stresses in the P20 clad have been investigated, and the results could be beneficial to more effective repair of damaged plastic injection molds made by P20 tool steel.

Aspects of the historical development of targetry for heavy ions of 0.05-2000 A centre dot MeV at GSI

CERN Document Server

Folger, H

1999-01-01

The progressively improved GSI accelerators provide beams of heavy ions from energies of 0.05-2000 A centre dot MeV at high particle intensities now. Therefore, a wide variety of common and new heavy-ion target techniques had to be installed and developed during the past 25 years to prepare and characterize self-supported or backed heavy-ion-targets of chemical elements and compounds from hydrogen (as polyethylene) to uranium. The thickness ranged from 2x10 sup - sup 6 to 20 g/cm sup 2 for beam spots of about 5 mm in diameter. Homogeneity, surface structure or individual shape had to be adapted to the needs of each experiment. Special setups were required for targets of poisonous materials, of highly enriched stable isotopes or those of radioactive species in minute amounts. The capability of thin-layer technologies was as well applied to prepare and measure stripper foils or various high-vacuum deposits for experimental or accelerator purposes. The development of different rotating target wheels and control ...

Recent developments in the synthesis of super heavy elements

International Nuclear Information System (INIS)

Ackermann, D.

2001-01-01

Throughout the passed two decades isotopes of the elements with atomic numbers 107-112 have been synthesized and unambiguously identified at the velocity filter SHIP at GSI. In a recent experiment at SHIP the results for element 112 have been confirmed and a third decay chain of the isotope 277 112 has been observed. Cold fusion reactions using Pb- and Bi- targets and evaporation residue(ER)-α-α correlations together with an efficient separation and detection system are the major ingredients for the success of these experiments. The sensitivity limit of the set-up at GSI has reached the 1pb level. For a systematic investigation in this region of the chart of nuclei and to synthesize heavier nuclei this limit has to be pushed to even lower values. An extensive development program is pursued at SHIP in order to reach at least an order of magnitude lower cross sections. Systematic investigations, the construction of decay chain networks and mass measurements are some of the possible approaches to study the decay chains attributed to isotopes of the elements 114, 116 and 118 at Dubna and Berkeley, which are, in contrast to those observed at GSI, not connected to decays of known isotopes. For the Berkeley results, in particular, several trials of confirmation have been undertaken at various laboratories including GSI

Comparative analysis among deterministic and stochastic collision damage models for oil tanker and bulk carrier reliability

Directory of Open Access Journals (Sweden)

A. Campanile

2018-01-01

Full Text Available The incidence of collision damage models on oil tanker and bulk carrier reliability is investigated considering the IACS deterministic model against GOALDS/IMO database statistics for collision events, substantiating the probabilistic model. Statistical properties of hull girder residual strength are determined by Monte Carlo simulation, based on random generation of damage dimensions and a modified form of incremental-iterative method, to account for neutral axis rotation and equilibrium of horizontal bending moment, due to cross-section asymmetry after collision events. Reliability analysis is performed, to investigate the incidence of collision penetration depth and height statistical properties on hull girder sagging/hogging failure probabilities. Besides, the incidence of corrosion on hull girder residual strength and reliability is also discussed, focussing on gross, hull girder net and local net scantlings, respectively. The ISSC double hull oil tanker and single side bulk carrier, assumed as test cases in the ISSC 2012 report, are taken as reference ships.

Location selection of agricultural-residuals particleboard industry through group decision: The case study of northern Iran

Directory of Open Access Journals (Sweden)

Majid Azizi

2016-12-01

Full Text Available This paper presents a framework for locating agricultural-residuals particleboard industry in the northern provinces of Iran. Particleboard industry is the only Iranian wood and paper industry with an export potential and the use of agricultural residuals as the raw material can help with increasing the production in this industry, while reducing the damage to forest resources. The northern provinces of Iran are agricultural centers with ample amounts of agricultural residues. These provinces are, therefore, preferable to other provinces as the construction sites of particleboard plants. In the location selection model presented in this paper, the Analytical Hierarchy Process (AHP method is used and the results indicate that the criterion of ‘material and production’ and the sub-criterion of ‘reliability of supply’ have the highest priorities, and that Golestan province is the best alternative.

Initiation and propagation of damage in actively cooled CFC armoured high heat flux components in fusion machines

International Nuclear Information System (INIS)

Chevet, G.; Schlosser, J.; Martin, E.; Herb, V.; Camus, G.; Escourbiac, F.

2009-01-01

Plasma facing components (PFCs) in magnetic confinement controlled fusion machines are armoured with carbon fibre composite (CFC) bonded to a copper alloy heat sink. The manufacturing process induces high level of residual stresses due to the thermal expansion mismatch between CFC and copper and PFCs have to withstand strong stress ranges during operation. To study the initiation and propagation of damage in the CFC part, the ONERA damage model is used to describe the behaviour of the N11 material. The finite element simulations show that the damage is located near the interface and develops during the manufacturing of the PFCs as a consequence of the high amplitude of shear stresses. Under high heat flux, stresses decrease and the damage does not evolve. Further studies will take into account the damageable behaviour of the composite/copper interface, which will lead to geometrical optimisations and better knowledge of the link between damage and conductivity.

Materials for Nuclear Plants From Safe Design to Residual Life Assessments

CERN Document Server

Hoffelner, Wolfgang

2013-01-01

The clamor for non-carbon dioxide emitting energy production has directly  impacted on the development of nuclear energy. As new nuclear plants are built, plans and designs are continually being developed to manage the range of challenging requirement and problems that nuclear plants face especially when managing the greatly increased operating temperatures, irradiation doses and extended design life spans. Materials for Nuclear Plants: From Safe Design to Residual Life Assessments  provides a comprehensive treatment of the structural materials for nuclear power plants with emphasis on advanced design concepts.   Materials for Nuclear Plants: From Safe Design to Residual Life Assessments approaches structural materials with a systemic approach. Important components and materials currently in use as well as those which can be considered in future designs are detailed, whilst the damage mechanisms responsible for plant ageing are discussed and explained. Methodologies for materials characterization, material...

Residues of acephate and its metabolite methamidophos in/on mango fruit (Mangifera indica L.).

Science.gov (United States)

Mohapatra, Soudamini; Ahuja, A K; Deepa, M; Sharma, Debi

2011-01-01

Mango, the major fruit crop of India is affected by stone weevil, which can cause serious damage to the fruits. Acephate gives good control of mango stone weevil. Residues of acephate and its major metabolite, methamidophos were evaluated on mango fruits following repeated spray applications at the recommended dose (0.75 kg a.i. ha⁻¹) and double the recommended dose (1.5 kg a.i. ha⁻¹). Acephate residues mostly remained on the fruit peel which persisted up to 30 days. Movement of residues to the fruit pulp was detected after 1 day of application, increased to maximum of 0.14 and 0.26 mg kg⁻¹ after 3 days and reached to below detectable level (BDL) after 20 days. Methamidophos, a metabolite of acephate, was detected from 3rd day onwards in both peel and pulp and persisted up to 15 days. The residues (acephate + methamidophos) dissipated with the half-life of 5 days in peel and pulp. A safe pre-harvest interval of 30 days is recommended for consumption of mango fruits following treatment of acephate at the recommended dose of 0.75 kg a.i. ha⁻¹.

Benfotiamine protects against peritoneal and kidney damage in peritoneal dialysis.

Science.gov (United States)

Kihm, Lars P; Müller-Krebs, Sandra; Klein, Julia; Ehrlich, Gregory; Mertes, Laura; Gross, Marie-Luise; Adaikalakoteswari, Antonysunil; Thornalley, Paul J; Hammes, Hans-Peter; Nawroth, Peter P; Zeier, Martin; Schwenger, Vedat

2011-05-01

Residual renal function and the integrity of the peritoneal membrane contribute to morbidity and mortality among patients treated with peritoneal dialysis. Glucose and its degradation products likely contribute to the deterioration of the remnant kidney and damage to the peritoneum. Benfotiamine decreases glucose-induced tissue damage, suggesting the potential for benefit in peritoneal dialysis. Here, in a model of peritoneal dialysis in uremic rats, treatment with benfotiamine decreased peritoneal fibrosis, markers of inflammation, and neovascularization, resulting in improved characteristics of peritoneal transport. Furthermore, rats treated with benfotiamine exhibited lower expression of advanced glycation endproducts and their receptor in the peritoneum and the kidney, reduced glomerular and tubulointerstitial damage, and less albuminuria. Increased activity of transketolase in tissue and blood contributed to the protective effects of benfotiamine. In primary human peritoneal mesothelial cells, the addition of benfotiamine led to enhanced transketolase activity and decreased expression of advanced glycation endproducts and their receptor. Taken together, these data suggest that benfotiamine protects the peritoneal membrane and remnant kidney in a rat model of peritoneal dialysis and uremia. Copyright © 2011 by the American Society of Nephrology

Environmental interpretation using insoluble residues within reef coral skeletons: problems, pitfalls, and preliminary results

Science.gov (United States)

Budd, Ann F.; Mann, Keith O.; Guzmán, Hector M.

1993-03-01

Insoluble residue concentrations have been measured within colonies of four massive reef corals from seven localities along the Caribbean coast of Panama to determine if detrital sediments, incorporated within the skeletal lattice during growth, record changes in sedimentation over the past twenty years. Amounts of resuspended sediment have increased to varying degrees at the seven localities over the past decades in response to increased deforestation in nearby terrestrial habitats. Preliminary results of correlation and regression analyses reveal few consistent temporal trends in the insoluble residue concentration. Analyses of variance suggest that amounts of insoluble residues, however, differ among environments within species, but that no consistent pattern of variation exists among species. D. strigosa and P. astreoides possess high concentrations at protected localities, S. siderea at localities with high amounts of resuspended sediment, and M. annularis at the least turbid localities. Little correlation exists between insoluble residue concentration and growth band width within species at each locality. Only in two more efficient suspension feeders ( S. siderea and D. strigosa) do weak negative correlations with growth band width exist overall. These results indicate that insoluble residue concentrations cannot be used unequivocally in environmental interpretation, until more is known about tissue damage, polyp behavior, and their effects on the incorporation of insolubles in the skeleton during growth in different coral species. Insoluble residue data are highly variable; therefore, large sample sizes and strong contrasts between environments are required to reveal significant trends.

Metabolite Damage and Metabolite Damage Control in Plants

Energy Technology Data Exchange (ETDEWEB)

Hanson, Andrew D. [Horticultural Sciences Department and; Henry, Christopher S. [Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, Illinois 60439, email:; Computation Institute, University of Chicago, Chicago, Illinois 60637; Fiehn, Oliver [Genome Center, University of California, Davis, California 95616, email:; de Crécy-Lagard, Valérie [Microbiology and Cell Science Department, University of Florida, Gainesville, Florida 32611, email: ,

2016-04-29

It is increasingly clear that (a) many metabolites undergo spontaneous or enzyme-catalyzed side reactions in vivo, (b) the damaged metabolites formed by these reactions can be harmful, and (c) organisms have biochemical systems that limit the buildup of damaged metabolites. These damage-control systems either return a damaged molecule to its pristine state (metabolite repair) or convert harmful molecules to harmless ones (damage preemption). Because all organisms share a core set of metabolites that suffer the same chemical and enzymatic damage reactions, certain damage-control systems are widely conserved across the kingdoms of life. Relatively few damage reactions and damage-control systems are well known. Uncovering new damage reactions and identifying the corresponding damaged metabolites, damage-control genes, and enzymes demands a coordinated mix of chemistry, metabolomics, cheminformatics, biochemistry, and comparative genomics. This review illustrates the above points using examples from plants, which are at least as prone to metabolite damage as other organisms.

Provisions against damage in permits of environment-related large facilities

International Nuclear Information System (INIS)

Wagner, H.

1980-01-01

The author in detail covers the legal treatment of technological risks, especially the roles played by experts and those applying the law, when it comes to the application of uncertain legal terms and criteria of evaluating the principle of provision for damage. He finds that an increasingly more important role was played by the legal evaluation of risks stemming from large technical facilities, in addition to the (socio-)political assessment of the consequences of technologies. For risk assessment, engineers had a primary responsibility, but the evaluation of risk in an overall process of weighing legal assets was a responsibility of lawyers. The residual risk to be tolerated legally (without the compulsory need to make provisions for damage) was to be determined by weighing legal assets, by the principle of adequacy, and by comparative risk assessment. (HSCH) [de

Estimación de la seguridad residual en estructuras de hormigón con problemas patológicos

Directory of Open Access Journals (Sweden)

Morán Cabré, F.

1994-12-01

Full Text Available The problems encountered in the survey, the diagnosis and the residual safety assessment of damaged reinforced concrete structures are schematically presented, together with the techniques and methods most commonly used for their solution.

Se presentan, de forma esquemática, los problemas que se plantean en la inspección, en el diagnóstico y en la estimación de la seguridad residual de estructuras de hormigón que presentan problemas patológicos, así como las técnicas y los métodos más comunes para su resolución.

Rosin-enabled ultraclean and damage-free transfer of graphene for large-area flexible organic light-emitting diodes

Science.gov (United States)

Zhang, Zhikun; Du, Jinhong; Zhang, Dingdong; Sun, Hengda; Yin, Lichang; Ma, Laipeng; Chen, Jiangshan; Ma, Dongge; Cheng, Hui-Ming; Ren, Wencai

2017-02-01

The large polymer particle residue generated during the transfer process of graphene grown by chemical vapour deposition is a critical issue that limits its use in large-area thin-film devices such as organic light-emitting diodes. The available lighting areas of the graphene-based organic light-emitting diodes reported so far are usually transfer method using rosin as a support layer, whose weak interaction with graphene, good solubility and sufficient strength enable ultraclean and damage-free transfer. The transferred graphene has a low surface roughness with an occasional maximum residue height of about 15 nm and a uniform sheet resistance of 560 Ω per square with about 1% deviation over a large area. Such clean, damage-free graphene has produced the four-inch monolithic flexible graphene-based organic light-emitting diode with a high brightness of about 10,000 cd m-2 that can already satisfy the requirements for lighting sources and displays.

A survey of residual analysis and a new test of residual trend.

Science.gov (United States)

McDowell, J J; Calvin, Olivia L; Klapes, Bryan

2016-05-01

A survey of residual analysis in behavior-analytic research reveals that existing methods are problematic in one way or another. A new test for residual trends is proposed that avoids the problematic features of the existing methods. It entails fitting cubic polynomials to sets of residuals and comparing their effect sizes to those that would be expected if the sets of residuals were random. To this end, sampling distributions of effect sizes for fits of a cubic polynomial to random data were obtained by generating sets of random standardized residuals of various sizes, n. A cubic polynomial was then fitted to each set of residuals and its effect size was calculated. This yielded a sampling distribution of effect sizes for each n. To test for a residual trend in experimental data, the median effect size of cubic-polynomial fits to sets of experimental residuals can be compared to the median of the corresponding sampling distribution of effect sizes for random residuals using a sign test. An example from the literature, which entailed comparing mathematical and computational models of continuous choice, is used to illustrate the utility of the test. © 2016 Society for the Experimental Analysis of Behavior.

Characterizing the glycocalyx of poultry spermatozoa: I. Identification and distribution of carbohydrate residues using flow cytometry and epifluorescence microscopy.

Science.gov (United States)

Peláez, Jesús; Long, Julie A

2007-01-01

The aim of the present work was to use a battery of lectins to 1) delineate the carbohydrate content of sperm glycocalyx in the turkey and chicken using flow cytometry analysis, and 2) evaluate the distribution of existing sugars over the sperm plasma membrane surface with epifluorescent microscopy. Carbohydrate groups (corresponding lectins) that were investigated included galactose (GS-I, Jacalin, RCA-I, PNA), glucose and/or mannose (Con A, PSA, GNA), N-acetyl-glucosamine (GS-II, s-WGA, STA), N-acetyl-galactosamine (SBA, WFA), fucose (Lotus, UEA-I), sialic acid (LFA, LPA), and N-acetyl-lactosamine (ECA). Spermatozoa were assessed before and after treatment with neuraminidase to remove sialic acid. Mean fluorescence intensity (MnFI) was used as indicator of lectin binding for flow cytometry analysis. Nontreated spermatozoa from both species showed high MnFI when incubated with RCA-I, Con A, LFA, and LPA, as did chicken spermatozoa incubated with s-WGA. Neuraminidase treatment increased the MnFI for most lectins except LFA and LPA, as expected. Differences in MnFI between species included higher values for s-WGA and ECA in chicken spermatozoa and for WFA in turkey spermatozoa. Microscopy revealed segregation of some sugar residues into membrane-specific domains; however, the 2 staining techniques (cell suspension vs fixed preparation) differed in identifying lectin binding patterns, with fixed preparations yielding a high degree of nonspecific binding. We conclude that 1) the glycocalyx of turkey and chicken spermatozoa contains a diversity of carbohydrate groups, 2) these residues are extensively masked by sialic acid, 3) the glycocalyx composition is species-specific, and 4) some glycoconjugates appear to be segregated into membrane-specific domains. Characterization of the poultry sperm glycocalyx is the first step in identifying the physiological impact of semen storage on sperm function.

Effect of benfotiamine in podocyte damage induced by peritoneal dialysis fluid

Directory of Open Access Journals (Sweden)

Sandra eMüller-Krebs

2015-03-01

Full Text Available Background:In peritoneal dialysis (PD residual renal function (RRF fundamentally contributes to improved quality of life and patient survival. High glucose and advanced glycation end-products (AGE contribute locally to peritoneal and systemically to renal damage. Integrity of podocyte structure and function is of special importance to preserve RRF. Benfotiamine could counteract the glucose and AGE mediated toxicity by blocking hyperglycemia associated podocyte damage via the pentose phosphate pathway.Methods: A human differentiated podocyte cell line was incubated with control solution (Control, 2.5% glucose solution (Glucose and 2.5% PD fluid (PDF for 48 h either ± 50 μM benfotiamine.Podocyte damage and potential benefit of benfotiamine were analyzed using immunofluorescence, western blot analysis, and a functional migration assay. For quantitation, a semiquantitative score was used. Results:When incubating podocytes with benfotiamine, Glucose and PDF mediated damage was reduced resulting in lower expression of AGE and intact podocin and ZO-1 localization. The reorganization of the actin cytoskeleton was restored in the presence of benfotiamine as functional podocyte motility reached Control level. Decreased level of inflammation could be shown as well as reduced podocyte apoptosis.Conclusions:These data suggest that benfotiamine protects podocytes from Glucose and PDF mediated dysfunction and damage, in particular with regard to cytoskeletal reorganization, motility, inflammation and podocyte survival.

Residual insufficiency of hematopoiesis after acute or chronic exposure to gamma radiation or neutrons

International Nuclear Information System (INIS)

Wangenheim, K.H. v.; Peterson, H.P.; Feinendegen, L.E.

1983-01-01

Recovery of the stem cell quality is possible after acute exposure to 500 rad γ radiation up to a period of 6 months. Beyond this data, a significant residual damage remains. The same applies to quantitative stem cell recovery. Chronic γ exposure leads to less radiation damage than acute exposure. After a total accumulation of 500 rad, the proliferation factors after chronic exposure were, on an average 20% higher than after acute radiation exposure. 6 MeV neutron exposure reduced the stem cell quality and stem cell count much more efficiently than γ exposure. The relative biological effect of neutrons is at least 2.5 times as high as the γ effect, both for the stem cell count and the stem cell quality. (orig.) [de

Spectroscopic investigation on assisted sonocatalytic damage of bovine serum albumin (BSA) by metronidazole (MTZ) under ultrasonic irradiation combined with nano-sized ZnO

Science.gov (United States)

Gao, Jingqun; Liu, Bin; Wang, Jun; Jin, Xudong; Jiang, Renzheng; Liu, Lijun; Wang, Baoxin; Xu, Yongnan

2010-11-01

The previous work proved that the bovine serum albumin (BSA) could be damaged under the combined action of ultrasonic irradiation and ZnO. In this work, the assisted sonocatalytic damage of BSA using metronidazole (MTZ) as a sensitizer was further investigated by means of UV-vis and fluorescence spectra. The results indicated that the adding of MTZ could obviously promote the sonocatalytic damage of BSA under ultrasonic irradiation in the presence of nano-sized ZnO powder. Furthermore, it was found that the damage degree of BSA was aggravated by some influencing factors except ionic kind and strength. In addition, the damage site of BSA was also studied with synchronous fluorescence technology. It was found that the damage site was mainly at tryptophan (Trp) residue.

Characterization of radiation damage induced by swift heavy ions in graphite

Energy Technology Data Exchange (ETDEWEB)

Hubert, Christian

2016-05-15

Graphite is a classical material in neutron radiation environments, being widely used in nuclear reactors and power plants as a moderator. For high energy particle accelerators, graphite provides ideal material properties because of the low Z of carbon and its corresponding low stopping power, thus when ion projectiles interact with graphite is the energy deposition rather low. This work aims to improve the understanding of how the irradiation with swift heavy ions (SHI) of kinetic energies in the range of MeV to GeV affects the structure of graphite and other carbon-based materials. Special focus of this project is given to beam induced changes of thermo-mechanical properties. For this purpose the Highly oriented pyrolytic graphite (HOPG) and glassy carbon (GC) (both serving as model materials), isotropic high density polycrystalline graphite (PG) and other carbon based materials like carbon fiber carbon composites (CFC), chemically expanded graphite (FG) and molybdenum carbide enhanced graphite composites (MoC) were exposed to different ions ranging from {sup 131}Xe to {sup 238}U provided by the UNILAC accelerator at GSI in Darmstadt, Germany. To investigate structural changes, various in-situ and off-line measurements were performed including Raman spectroscopy, x-ray diffraction and x-ray photo-electron spectroscopy. Thermo-mechanical properties were investigated using the laser-flash-analysis method, differential scanning calorimetry, micro/nano-indentation and 4-point electrical resistivity measurements. Beam induced stresses were investigated using profilometry. Obtained results provided clear evidence that ion beam-induced radiation damage leads to structural changes and degradation of thermal, mechanical and electrical properties of graphite. PG transforms towards a disordered sp2 structure, comparable to GC at high fluences. Irradiation-induced embrittlement is strongly reducing the lifetime of most high-dose exposed accelerator components. For

Influence of Initial Inclined Surface Crack on Estimated Residual Fatigue Lifetime of Railway Axle

Czech Academy of Sciences Publication Activity Database

Náhlík, Luboš; Pokorný, Pavel; Ševčík, Martin; Hutař, Pavel

2016-01-01

Roč. 7, č. 4 (2016), č. článku 1640007. ISSN 1756-9737. [FDM 2016 - International Conference on Fracture and Damage Mechanics /15./. Alicante, 14.09.2016-16.09.2016] R&D Projects: GA MŠk LM2015069; GA MŠk(CZ) ED1.1.00/02.0068 Institutional support: RVO:68081723 Keywords : inclined crack * railway axle * residual fatigue lifetime * fatigue crack propagation Subject RIV: JL - Materials Fatigue, Friction Mechanics

Modelling Of Residual Stresses Induced By High Speed Milling Process

International Nuclear Information System (INIS)

Desmaison, Olivier; Mocellin, Katia; Jardin, Nicolas

2011-01-01

Maintenance processes used in heavy industries often include high speed milling operations. The reliability of the post-process material state has to be studied. Numerical simulation appears to be a very interesting way to supply an efficient residual stresses (RS) distribution prediction.Because the adiabatic shear band and the serrated chip shaping are features of the austenitic stainless steel high speed machining, a 2D high speed orthogonal cutting model is briefly presented. This finite element model, developed on Forge registered software, is based on data taken from Outeiro and al.'s paper [1]. A new behaviour law fully coupling Johnson-Cook's constitutive law and Latham and Cockcroft's damage model is detailed in this paper. It ensures results that fit those found in literature.Then, the numerical tools used on the 2D model are integrated to a 3D high speed milling model. Residual stresses distribution is analysed, on the surface and into the depth of the material. Various revolutions and passes of the two teeth hemispheric mill on the workpiece are simulated. Thus the sensitivity of the residual stresses generation to the cutting conditions can be discussed. In order to validate the 3D model, a comparison of the cutting forces measured by EDF R and D to those given by numerical simulations is achieved.

A residue-free green synergistic antifungal nanotechnology for pesticide thiram by ZnO nanoparticles

Science.gov (United States)

Xue, Jingzhe; Luo, Zhihui; Li, Ping; Ding, Yaping; Cui, Yi; Wu, Qingsheng

2014-07-01

Here we reported a residue-free green nanotechnology which synergistically enhance the pesticides efficiency and successively eliminate its residue. We built up a composite antifungal system by a simple pre-treating and assembling procedure for investigating synergy. Investigations showed 0.25 g/L ZnO nanoparticles (NPs) with 0.01 g/L thiram could inhibit the fungal growth in a synergistic mode. More importantly, the 0.25 g/L ZnO NPs completely degraded 0.01 g/L thiram under simulated sunlight irradiation within 6 hours. It was demonstrated that the formation of ZnO-thiram antifungal system, electrostatic adsorption of ZnO NPs to fungi cells and the cellular internalization of ZnO-thiram composites played important roles in synergy. Oxidative stress test indicated ZnO-induced oxidative damage was enhanced by thiram that finally result in synergistic antifungal effect. By reducing the pesticides usage, this nanotechnology could control the plant disease economically, more significantly, the following photocatalytic degradation of pesticide greatly benefit the human social by avoiding negative influence of pesticide residue on public health and environment.

Effects of crop sanitation on banana weevil, Cosmopolites sordidus (Germar) (Coleoptera : Curculionidae), populations and crop damage in Uganda

NARCIS (Netherlands)

Masanza, M.; Gold, C.S.; Huis, van A.; Ragama, P.E.

2006-01-01

Crop sanitation, i.e. destruction of crop residues, has been hypothesized to lower banana weevil damage by removing adult refuges and breeding sites. Although it has been widely recommended to farmers, limited data are available to demonstrate the efficacy of this method. The effects of crop

Evaluation of residue-residue contact predictions in CASP9

KAUST Repository

Monastyrskyy, Bohdan; Fidelis, Krzysztof; Tramontano, Anna; Kryshtafovych, Andriy

2011-01-01

This work presents the results of the assessment of the intramolecular residue-residue contact predictions submitted to CASP9. The methodology for the assessment does not differ from that used in previous CASPs, with two basic evaluation measures

Molecular and histological evaluation of tributyltin toxicity on spermatogenesis in a marine fish, the mummichog (Fundulus heteroclitus)

Energy Technology Data Exchange (ETDEWEB)

Mochida, Kazuhiko [National Research Institute of Fisheries and Environment of Inland Sea, Fisheries Research Agency, Maruishi 2-17-5, Hatsukaichi, Hiroshima 739-0452 (Japan)]. E-mail: kmochida@fra.affrc.go.jp; Ito, Katsutoshi [National Research Institute of Fisheries and Environment of Inland Sea, Fisheries Research Agency, Maruishi 2-17-5, Hatsukaichi, Hiroshima 739-0452 (Japan); Kono, Kumiko [National Research Institute of Fisheries and Environment of Inland Sea, Fisheries Research Agency, Maruishi 2-17-5, Hatsukaichi, Hiroshima 739-0452 (Japan); Onduka, Toshimitsu [National Research Institute of Fisheries and Environment of Inland Sea, Fisheries Research Agency, Maruishi 2-17-5, Hatsukaichi, Hiroshima 739-0452 (Japan); Kakuno, Akira [National Research Institute of Fisheries and Environment of Inland Sea, Fisheries Research Agency, Maruishi 2-17-5, Hatsukaichi, Hiroshima 739-0452 (Japan); Fujii, Kazunori [National Research Institute of Fisheries and Environment of Inland Sea, Fisheries Research Agency, Maruishi 2-17-5, Hatsukaichi, Hiroshima 739-0452 (Japan)

2007-06-05

There is still concern about the effects of organotin compounds (OTs) on marine organisms, and especially on their reproductive systems. We investigated the toxicity of tributyltin oxide (TBTO) on spermatogenesis in a marine fish, mummichog, Fundulus heteroclitus. TBTO exposure caused serious histological damage to the testis, including reduction in counts of spermatids and spermatozoa and malformation of somatic cells around the seminal duct. Analysis of the incorporation of bromodeoxyuridine into spermatogenic cells revealed inhibition of the proliferation of germ cells. To find a biomarker for evaluation of the effects of TBTO on fish spermatogenesis, we cloned genes downregulated by TBTO exposure in the mummichog testis, and identified mummichog creatine kinase (mCK). The cDNA sequence of mCK contained an open reading frame encoding 387 amino acid residues (M {sub r} = 43,344). The derived amino acid sequence of mCK was very similar to that of the testicular-type CK of the rainbow trout, Oncorhynchus mykiss. Furthermore, Northern blot analysis revealed that mCK was produced specifically in the testis. We therefore identified mCK in the mummichog as a testicular-type CK. Real-time PCR revealed that exposure of the fish to TBTO significantly reduced mCK expression in the testis. To some extent, this reduction was coincident with that of bromodeoxyuridine incorporation into spermatogenic cells. The mCK gene can therefore be used as a biomarker for evaluating the effects of TBTO on fish spermatogenesis. In addition, levels of expression of the mCK gene in control fish were well correlated with increments in the gonad somatic index (GSI) below 4%. Individuals that were thought to have testicular damage caused by TBTO could be discriminated from those considered normal. The results suggest that TBTO is involved in the suppression of fish spermatogenesis and that analysis of both GSI values and mCK gene expression is useful for evaluating the levels of xenobiotic

Molecular and histological evaluation of tributyltin toxicity on spermatogenesis in a marine fish, the mummichog (Fundulus heteroclitus)

International Nuclear Information System (INIS)

Mochida, Kazuhiko; Ito, Katsutoshi; Kono, Kumiko; Onduka, Toshimitsu; Kakuno, Akira; Fujii, Kazunori

2007-01-01

There is still concern about the effects of organotin compounds (OTs) on marine organisms, and especially on their reproductive systems. We investigated the toxicity of tributyltin oxide (TBTO) on spermatogenesis in a marine fish, mummichog, Fundulus heteroclitus. TBTO exposure caused serious histological damage to the testis, including reduction in counts of spermatids and spermatozoa and malformation of somatic cells around the seminal duct. Analysis of the incorporation of bromodeoxyuridine into spermatogenic cells revealed inhibition of the proliferation of germ cells. To find a biomarker for evaluation of the effects of TBTO on fish spermatogenesis, we cloned genes downregulated by TBTO exposure in the mummichog testis, and identified mummichog creatine kinase (mCK). The cDNA sequence of mCK contained an open reading frame encoding 387 amino acid residues (M r = 43,344). The derived amino acid sequence of mCK was very similar to that of the testicular-type CK of the rainbow trout, Oncorhynchus mykiss. Furthermore, Northern blot analysis revealed that mCK was produced specifically in the testis. We therefore identified mCK in the mummichog as a testicular-type CK. Real-time PCR revealed that exposure of the fish to TBTO significantly reduced mCK expression in the testis. To some extent, this reduction was coincident with that of bromodeoxyuridine incorporation into spermatogenic cells. The mCK gene can therefore be used as a biomarker for evaluating the effects of TBTO on fish spermatogenesis. In addition, levels of expression of the mCK gene in control fish were well correlated with increments in the gonad somatic index (GSI) below 4%. Individuals that were thought to have testicular damage caused by TBTO could be discriminated from those considered normal. The results suggest that TBTO is involved in the suppression of fish spermatogenesis and that analysis of both GSI values and mCK gene expression is useful for evaluating the levels of xenobiotic pollution

Structural damage diagnosis based on on-line recursive stochastic subspace identification

International Nuclear Information System (INIS)

Loh, Chin-Hsiung; Weng, Jian-Huang; Liu, Yi-Cheng; Lin, Pei-Yang; Huang, Shieh-Kung

2011-01-01

This paper presents a recursive stochastic subspace identification (RSSI) technique for on-line and almost real-time structural damage diagnosis using output-only measurements. Through RSSI the time-varying natural frequencies of a system can be identified. To reduce the computation time in conducting LQ decomposition in RSSI, the Givens rotation as well as the matrix operation appending a new data set are derived. The relationship between the size of the Hankel matrix and the data length in each shifting moving window is examined so as to extract the time-varying features of the system without loss of generality and to establish on-line and almost real-time system identification. The result from the RSSI technique can also be applied to structural damage diagnosis. Off-line data-driven stochastic subspace identification was used first to establish the system matrix from the measurements of an undamaged (reference) case. Then the RSSI technique incorporating a Kalman estimator is used to extract the dynamic characteristics of the system through continuous monitoring data. The predicted residual error is defined as a damage feature and through the outlier statistics provides an indicator of damage. Verification of the proposed identification algorithm by using the bridge scouring test data and white noise response data of a reinforced concrete frame structure is conducted

Time course of pulmonary burden in mice exposed to residual oil fly ash

OpenAIRE

Giovanna Marcella Cavalcante Carvalho; Lilian Katie Nagato; Sheila da Silva Fagundes; Flavia Brandão dos Santos; Andrea Surrage Calheiros; Olaf eMalm; Patricia Torres Bozza; Paulo Hilario Nascimento Saldiva; Debora Souza Faffe; Patricia Rieken Macedo Rocco; Walter Araujo Zin

2014-01-01

Residual oil fly ash (ROFA) is a common pollutant in areas where oil is burned. This particulate matter (PM) with a broad distribution of particle diameters can be inhaled by human beings and putatively damage their respiratory system. Although some studies deal with cultured cells, animals, and even epidemiological issues, so far a comprehensive analysis of respiratory outcomes as a function of the time elapsed after exposure to a low dose of ROFA is wanted. Thus, we aimed to investigate the...

Process induced sub-surface damage in mechanically ground silicon wafers

International Nuclear Information System (INIS)

Yang Yu; De Munck, Koen; Teixeira, Ricardo Cotrin; Swinnen, Bart; De Wolf, Ingrid; Verlinden, Bert

2008-01-01

Micro-Raman spectroscopy, scanning electron microcopy, atomic force microscopy and preferential etching were used to characterize the sub-surface damage induced by the rough and fine grinding steps used to make ultra-thin silicon wafers. The roughly and ultra-finely ground silicon wafers were examined on both the machined (1 0 0) planes and the cross-sectional (1 1 0) planes. They reveal similar multi-layer damage structures, consisting of amorphous, plastically deformed and elastically stressed layers. However, the thickness of each layer in the roughly ground sample is much higher than its counterpart layers in the ultra-finely ground sample. The residual stress after rough and ultra-fine grinding is in the range of several hundreds MPa and 30 MPa, respectively. In each case, the top amorphous layer is believed to be the result of sequential phase transformations (Si-I to Si-II to amorphous Si). These phase transformations correspond to a ductile grinding mechanism, which is dominating in ultra-fine grinding. On the other hand, in rough grinding, a mixed mechanism of ductile and brittle grinding causes multi-layer damage and sub-surface cracks

Review of Repair Materials for Fire-Damaged Reinforced Concrete Structures

Science.gov (United States)

Zahid, MZA Mohd; Abu Bakar, BH; Nazri, FM; Ahmad, MM; Muhamad, K.

2018-03-01

Reinforced concrete (RC) structures perform well during fire and may be repaired after the fire incident because their low heat conductivity prevents the loss or degradation of mechanical strength of the concrete core and internal reinforcing steel. When an RC structure is heated to more than 500 °C, mechanical properties such as compressive strength, stiffness, and tensile strength start to degrade and deformations occur. Although the fire-exposed RC structure shows no visible damage, its residual strength decreases compared with that in the pre-fire state. Upon thorough assessment, the fire-damaged RC structure can be repaired or strengthened, instead of subjecting to partial or total demolition followed by reconstruction. The structure can be repaired using several materials, such as carbon fiber-reinforced polymer, glass fiber-reinforced polymer, normal strength concrete, fiber-reinforced concrete, ferrocement, epoxy resin mortar, and high-performance concrete. Selecting an appropriate repair material that must be compatible with the substrate or base material is a vital step to ensure successful repair. This paper reviews existing repair materials and factors affecting their performance. Of the materials considered, ultra-high-performance fiber-reinforced concrete (UHPFRC) exhibits huge potential for repairing fire-damaged RC structures but lack of information available. Hence, further studies must be performed to assess the potential of UHPFRC in rehabilitating fire-damaged RC structures.

Computational stress and damage modelling for rolling contact fatigue

DEFF Research Database (Denmark)

Cerullo, Michele

Rolling contact fatigue in radial roller bearings is studied by means of a 2D plane strain nite element program. The Dang Van multiaxial fatigue criterion is firstly used, in a macroscopic study modeling the bearing raceway, to investigate the region where fatigue cracks are more likely to nucleate...... and of compressive residual stresses are also analyzed. The stress history of a material point at the depth where the maximum Dang Van damage factor is reached is then recorded and used in a subsequent micro-mechanical analysis. The stress history is applied as periodic boundary conditions in a representative volume...

Enzymatic recognition of DNA damage induced by UVB-photosensitized titanium dioxide and biological consequences in Saccharomyces cerevisiae: Evidence for oxidatively DNA damage generation

International Nuclear Information System (INIS)

Pinto, A. Viviana; Deodato, Elder L.; Cardoso, Janine S.; Oliveira, Eliza F.; Machado, Sergio L.; Toma, Helena K.; Leitao, Alvaro C.; Padula, Marcelo de

2010-01-01

Although titanium dioxide (TiO 2 ) has been considered to be biologically inert, finding use in cosmetics, paints and food colorants, recent reports have demonstrated that when TiO 2 is attained by UVA radiation oxidative genotoxic and cytotoxic effects are observed in living cells. However, data concerning TiO 2 -UVB association is poor, even if UVB radiation represents a major environmental carcinogen. Herein, we investigated DNA damage, repair and mutagenesis induced by TiO 2 associated with UVB irradiation in vitro and in vivo using Saccharomyces cerevisiae model. It was found that TiO 2 plus UVB treatment in plasmid pUC18 generated, in addition to cyclobutane pyrimidine dimers (CPDs), specific damage to guanine residues, such as 8-oxo-7,8-dihydroguanine (8-oxoG) and 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG), which are characteristic oxidatively generated lesions. In vivo experiments showed that, although the presence of TiO 2 protects yeast cells from UVB cytotoxicity, high mutation frequencies are observed in the wild-type (WT) and in an ogg1 strain (deficient in 8-oxoG and FapyG repair). Indeed, after TiO 2 plus UVB treatment, induced mutagenesis was drastically enhanced in ogg1 cells, indicating that mutagenic DNA lesions are repaired by the Ogg1 protein. This effect could be attenuated by the presence of metallic ion chelators: neocuproine or dipyridyl, which partially block oxidatively generated damage occurring via Fenton reactions. Altogether, the results indicate that TiO 2 plus UVB potentates UVB oxidatively generated damage to DNA, possibly via Fenton reactions involving the production of DNA base damage, such as 8-oxo-7,8-dihydroguanine.

Rigid Residue Scan Simulations Systematically Reveal Residue Entropic Roles in Protein Allostery.

Directory of Open Access Journals (Sweden)

Robert Kalescky

2016-04-01

Full Text Available Intra-protein information is transmitted over distances via allosteric processes. This ubiquitous protein process allows for protein function changes due to ligand binding events. Understanding protein allostery is essential to understanding protein functions. In this study, allostery in the second PDZ domain (PDZ2 in the human PTP1E protein is examined as model system to advance a recently developed rigid residue scan method combining with configurational entropy calculation and principal component analysis. The contributions from individual residues to whole-protein dynamics and allostery were systematically assessed via rigid body simulations of both unbound and ligand-bound states of the protein. The entropic contributions of individual residues to whole-protein dynamics were evaluated based on covariance-based correlation analysis of all simulations. The changes of overall protein entropy when individual residues being held rigid support that the rigidity/flexibility equilibrium in protein structure is governed by the La Châtelier's principle of chemical equilibrium. Key residues of PDZ2 allostery were identified with good agreement with NMR studies of the same protein bound to the same peptide. On the other hand, the change of entropic contribution from each residue upon perturbation revealed intrinsic differences among all the residues. The quasi-harmonic and principal component analyses of simulations without rigid residue perturbation showed a coherent allosteric mode from unbound and bound states, respectively. The projection of simulations with rigid residue perturbation onto coherent allosteric modes demonstrated the intrinsic shifting of ensemble distributions supporting the population-shift theory of protein allostery. Overall, the study presented here provides a robust and systematic approach to estimate the contribution of individual residue internal motion to overall protein dynamics and allostery.

Evolutionary patterns at the RNase based gametophytic self - incompatibility system in two divergent Rosaceae groups (Maloideae and Prunus).

Science.gov (United States)

Vieira, Jorge; Ferreira, Pedro G; Aguiar, Bruno; Fonseca, Nuno A; Vieira, Cristina P

2010-06-28

Within Rosaceae, the RNase based gametophytic self-incompatibility (GSI) system has been studied at the molecular level in Maloideae and Prunus species that have been diverging for, at least, 32 million years. In order to understand RNase based GSI evolution within this family, comparative studies must be performed, using similar methodologies. It is here shown that many features are shared between the two species groups such as levels of recombination at the S-RNase (the S-pistil component) gene, and the rate at which new specificities arise. Nevertheless, important differences are found regarding the number of ancestral lineages and the degree of specificity sharing between closely related species. In Maloideae, about 17% of the amino acid positions at the S-RNase protein are found to be positively selected, and they occupy about 30% of the exposed protein surface. Positively selected amino acid sites are shown to be located on either side of the active site cleft, an observation that is compatible with current models of specificity determination. At positively selected amino acid sites, non-conservative changes are almost as frequent as conservative changes. There is no evidence that at these sites the most drastic amino acid changes may be more strongly selected. Many similarities are found between the GSI system of Prunus and Maloideae that are compatible with the single origin hypothesis for RNase based GSI. The presence of common features such as the location of positively selected amino acid sites and lysine residues that may be important for ubiquitylation, raise a number of issues that, in principle, can be experimentally addressed in Maloideae. Nevertheless, there are also many important differences between the two Rosaceae GSI systems. How such features changed during evolution remains a puzzling issue.

Evolutionary patterns at the RNase based gametophytic self - incompatibility system in two divergent Rosaceae groups (Maloideae and Prunus

Directory of Open Access Journals (Sweden)

Fonseca Nuno A

2010-06-01

Full Text Available Abstract Background Within Rosaceae, the RNase based gametophytic self-incompatibility (GSI system has been studied at the molecular level in Maloideae and Prunus species that have been diverging for, at least, 32 million years. In order to understand RNase based GSI evolution within this family, comparative studies must be performed, using similar methodologies. Result It is here shown that many features are shared between the two species groups such as levels of recombination at the S-RNase (the S-pistil component gene, and the rate at which new specificities arise. Nevertheless, important differences are found regarding the number of ancestral lineages and the degree of specificity sharing between closely related species. In Maloideae, about 17% of the amino acid positions at the S-RNase protein are found to be positively selected, and they occupy about 30% of the exposed protein surface. Positively selected amino acid sites are shown to be located on either side of the active site cleft, an observation that is compatible with current models of specificity determination. At positively selected amino acid sites, non-conservative changes are almost as frequent as conservative changes. There is no evidence that at these sites the most drastic amino acid changes may be more strongly selected. Conclusions Many similarities are found between the GSI system of Prunus and Maloideae that are compatible with the single origin hypothesis for RNase based GSI. The presence of common features such as the location of positively selected amino acid sites and lysine residues that may be important for ubiquitylation, raise a number of issues that, in principle, can be experimentally addressed in Maloideae. Nevertheless, there are also many important differences between the two Rosaceae GSI systems. How such features changed during evolution remains a puzzling issue.

Acoustic Emission Monitoring of Compression-after-Impact Test of Nano-Particles-Coated CFRP Damaged by Simulated Lightning Strikes

Energy Technology Data Exchange (ETDEWEB)

Shin, Je Ha; Kwon, Oh Yang; Seo, Seong Wook [Inha University, Incheon (Korea, Republic of)

2011-02-15

Nanoparticles-coated and impact-damaged carbon-fiber reinforced plastics(CFRP) laminates were tested under compression-after-impact(CAI) mode and the propagation of damage due to compressive loading has been monitored by acoustic emission(AE). The impact damage was induced not by mechanical loading but by a simulated lightning strike. CFRP laminates were made of carbon prepregs prepared by coating of conductive nano-particles directly on the fibers and the coupons were subjected to simulated lightning strikes with a high voltage/current impulse of 10{approx}40 kA within a few microseconds. The effects of nano-particles coating and the degree of damage induced by the simulated lightning strikes on the AE activities were examined, and the relationship between the compressive residual strength and AE behavior has been evaluated in terms of AE event counts and the onset of AE activity with the compressive loading. The degree of impact damage was also measured in terns of damage area by using ultrasonic C-scan images. From the results assessed during the CAI tests of damaged CFRP showed that AE monitoring appeared to be very useful to differentiate the degree of damage hence the mechanical integrity of composite structures damaged by lightning strikes

Acoustic Emission Monitoring of Compression-after-Impact Test of Nano-Particles-Coated CFRP Damaged by Simulated Lightning Strikes

International Nuclear Information System (INIS)

Shin, Je Ha; Kwon, Oh Yang; Seo, Seong Wook

2011-01-01

Nanoparticles-coated and impact-damaged carbon-fiber reinforced plastics(CFRP) laminates were tested under compression-after-impact(CAI) mode and the propagation of damage due to compressive loading has been monitored by acoustic emission(AE). The impact damage was induced not by mechanical loading but by a simulated lightning strike. CFRP laminates were made of carbon prepregs prepared by coating of conductive nano-particles directly on the fibers and the coupons were subjected to simulated lightning strikes with a high voltage/current impulse of 10∼40 kA within a few microseconds. The effects of nano-particles coating and the degree of damage induced by the simulated lightning strikes on the AE activities were examined, and the relationship between the compressive residual strength and AE behavior has been evaluated in terms of AE event counts and the onset of AE activity with the compressive loading. The degree of impact damage was also measured in terns of damage area by using ultrasonic C-scan images. From the results assessed during the CAI tests of damaged CFRP showed that AE monitoring appeared to be very useful to differentiate the degree of damage hence the mechanical integrity of composite structures damaged by lightning strikes

Miscoding and mutagenic properties of 8-oxoguanine and abasic sites: Ubiquitous lesions in damaged DNA

International Nuclear Information System (INIS)

Grollman, A.P.; Takeshita, Masaru

1995-01-01

More than twenty oxidatively-damaged bases, including 8-oxoguanine, have been found to occur in genomic DNA. Some of these lesions block DNA replication and are potentially lethal; others generate mutations which can initiate carcinogenesis and promote cellular aging. In this report, the authors focus attention on the mutagenicity and repair of 8-oxoguanine. Kasai and Nishimura's discovery that hydroxyl radicals react with guanine residues in DNA to form 8-oxoguanine and the development of sensitive methods for the detection and quantitation of this modified base led to the observation that approximately 1 in 10 5 guanine residues in mammalian DNA are oxidized at the C-8 position. DNA containing 8-oxoguanine and synthetic analogs of the abasic site have been used to investigate the miscoding and mutagenic potential of these ubiquitous lesions. Studies in the laboratory were facilitated by the development of solid state synthetic methods by which these lesions could be introduced at defined positions in DNA. In this paper, the authors review studies in which 8-oxoguanine and abasic sites have been used in model systems to explore various early events in the replication of selectively damaged DNA

First superheavy element experiments at the GSI recoil separator TASCA: The production and decay of element 114 in the 244Pu(48Ca,3-4n) reaction

International Nuclear Information System (INIS)

Gates, J. M.; Duellmann, Ch. E.; Schaedel, M.; Ackermann, D.; Block, M.; Bruechle, W.; Essel, H. G.; Hartmann, W.; Hessberger, F. P.; Huebner, A.; Jaeger, E.; Khuyagbaatar, J.; Kindler, B.; Krier, J.; Kurz, N.; Lommel, B.; Schaffner, H.; Schausten, B.; Schimpf, E.; Steiner, J.

2011-01-01

Experiments with the new recoil separator, Transactinide Separator and Chemistry Apparatus (TASCA), at the GSI were performed by using beams of 48 Ca to irradiate targets of 206-208 Pb, which led to the production of 252-254 No isotopes. These studies allowed for evaluation of the performance of TASCA when coupled to a new detector and electronics system. By following these studies, the isotopes of element 114 ( 288-291 114) were produced in irradiations of 244 Pu targets with 48 Ca beams at compound nucleus excitation energies around 41.7 and 37.5 MeV, demonstrating TASCA's ability to perform experiments with picobarn-level cross sections. A total of 15 decay chains were observed and were assigned to the decay of 288-291 114. A new α-decay branch in 281 Ds was observed, leading to the new nucleus 277 Hs.

Development of a Relationship Between Residual Ultimate Longitudinal Strength Versus Grounding Damage Index Diagram For Container Ships

DEFF Research Database (Denmark)

Kim, Do Kyun; Kim, Han Byul; Zhang, Xiaoming

2012-01-01

Various accidents such as grounding, collision, fire, and explosion commonly occur on operating ships. The structural damage caused by such accidents is often accompanied by casualties and serious pollution. Therefore, an accidental risk- based approach that is in line with the goal-based standard...

Spatial-temporal ultrasound imaging of residual cavitation bubbles around a fluid-tissue interface in histotripsy.

Science.gov (United States)

Hu, Hong; Xu, Shanshan; Yuan, Yuan; Liu, Runna; Wang, Supin; Wan, Mingxi

2015-05-01

Cavitation is considered as the primary mechanism of soft tissue fragmentation (histotripsy) by pulsed high-intensity focused ultrasound. The residual cavitation bubbles have a dual influence on the histotripsy pulses: these serve as nuclei for easy generation of new cavitation, and act as strong scatterers causing energy "shadowing." To monitor the residual cavitation bubbles in histotripsy, an ultrafast active cavitation imaging method with relatively high signal-to-noise ratio and good spatial-temporal resolution was proposed in this paper, which combined plane wave transmission, minimum variance beamforming, and coherence factor weighting. The spatial-temporal evolutions of residual cavitation bubbles around a fluid-tissue interface in histotripsy under pulse duration (PD) of 10-40 μs and pulse repetition frequency (PRF) of 0.67-2 kHz were monitored by this method. The integrated bubble area curves inside the tissue interface were acquired from the bubble image sequence, and the formation process of histotripsy damage was estimated. It was observed that the histotripsy efficiency decreased with both longer PDs and higher PRFs. A direct relationship with a coefficient of 1.0365 between histotripsy lesion area and inner residual bubble area was found. These results can assist in monitoring and optimization of the histotripsy treatment further.

Damage assessment in CFRP laminates exposed to impact fatigue loading

International Nuclear Information System (INIS)

Tsigkourakos, George; Silberschmidt, Vadim V; Ashcroft, I A

2011-01-01

Demand for advanced engineering composites in the aerospace industry is increasing continuously. Lately, carbon fibre reinforced polymers (CFRPs) became one of the most important structural materials in the industry due to a combination of characteristics such as: excellent stiffness, high strength-to-weight ratio, and ease of manufacture according to application. In service, aerospace composite components and structures are exposed to various transient loads, some of which can propagate in them as cyclic impacts. A typical example is an effect of the wind gusts during flight. This type of loading is known as impact fatigue (IF); it is a repetition of low-energy impacts. Such loads can cause various types of damage in composites: fibre breaking, transverse matrix cracking, de-bonding between fibres and matrix and delamination resulting in reduction of residual stiffness and loss of functionality. Furthermore, this damage is often sub-surface, which reinforces the need for more regular inspection. The effects of IF are of major importance due its detrimental effect on the structural integrity of components that can be generated after relatively few impacts at low force levels compared to those in a standard fatigue regime. This study utilises an innovative testing system with the capability of subjecting specimens to a series of repetitive impacts. The primary subject of this paper is to assess the damaging effect of IF on the behaviour of drilled CFRP specimens, exposed to such loading. A detailed damage analysis is implemented utilising an X-ray micro computed tomography system. The main findings suggested that at early stages of life damage is governed by o degree splits along the length of the specimens resulting in a 20% reduction of stiffness. The final failure damage scenario indicated that transverse crasks in the 90 degree plies are the main reason for complete delamination which can be translated to a 50% stiffness reduction.

Residual gas analysis

International Nuclear Information System (INIS)

Berecz, I.

1982-01-01

Determination of the residual gas composition in vacuum systems by a special mass spectrometric method was presented. The quadrupole mass spectrometer (QMS) and its application in thin film technology was discussed. Results, partial pressure versus time curves as well as the line spectra of the residual gases in case of the vaporization of a Ti-Pd-Au alloy were demonstrated together with the possible construction schemes of QMS residual gas analysers. (Sz.J.)

Assessing the Availability of Wood Residues and Residue Markets in Virginia

OpenAIRE

Alderman, Delton R. Jr.

1998-01-01

A statewide mail survey of primary and secondary wood product manufacturers was undertaken to quantify the production and consumption of wood residues in Virginia. Two hundred and sixty-six wood product manufacturers responded to the study and they provided information on the production, consumption, markets, income or disposal costs, and disposal methods of wood residues. Hardwood and pine sawmills produce approximately 66 percent of Virginia's wood residues. Virginia's wood product man...

Damage analysis: damage function development and application

International Nuclear Information System (INIS)

Simons, R.L.; Odette, G.R.

1975-01-01

The derivation and application of damage functions, including recent developments for the U.S. LMFBR and CTR programs, is reviewed. A primary application of damage functions is in predicting component life expectancies; i.e., the fluence required in a service spectrum to attain a specified design property change. An important part of the analysis is the estimation of the uncertainty in such fluence limit predictions. The status of standardizing the procedures for the derivation and application of damage functions is discussed. Improvements in several areas of damage function development are needed before standardization can be completed. These include increasing the quantity and quality of the data used in the analysis, determining the limitations of the analysis due to the presence of multiple damage mechanisms, and finally, testing of damage function predictions against data obtained from material surveillance programs in operating thermal and fast reactors. 23 references. (auth)

Mutational properties of amino acid residues: implications for evolvability of phosphorylatable residues

DEFF Research Database (Denmark)

Creixell, Pau; Schoof, Erwin M.; Tan, Chris Soon Heng

2012-01-01

in terms of their mutational activity. Moreover, we highlight the importance of the genetic code and physico-chemical properties of the amino acid residues as likely causes of these inequalities and uncover serine as a mutational hot spot. Finally, we explore the consequences that these different......; it is typically assumed that all amino acid residues are equally likely to mutate or to result from a mutation. Here, by reconstructing ancestral sequences and computing mutational probabilities for all the amino acid residues, we refute this assumption and show extensive inequalities between different residues...... mutational properties have on phosphorylation site evolution, showing that a higher degree of evolvability exists for phosphorylated threonine and, to a lesser extent, serine in comparison with tyrosine residues. As exemplified by the suppression of serine's mutational activity in phosphorylation sites, our...

ACCOUNTING OF ENVIRONMENTAL DAMAGE IN THE DESIGN OF MINING OBJECTS

Directory of Open Access Journals (Sweden)

A. M. Maksimova

2016-01-01

Full Text Available The purpose of this article is to study the existing methods of calculation of environmental damage and identifying the most effective ones. To achieve this goal, the author has formulated and solved the following tasks: to investigate the mining sector, given its environmental safety; to define the stages of development of deposits of rare earth metals and to assess their level of environmental damage.The theoretical basis of the article is the domestic and foreign scholars on various aspects of the world energy market the hydrocarbon resources and the economy of industrial enterprises. As a methodological basis of applied methods: analysis, synthesis, analogy, comparison, induction and deduction, mathematical-statistical (factor.In the result of the study revealed that the greatest importance and practical significance is a methodology  based on the effectiveness of environmental protection measures as it may consider three types of environmental risks: environmental damage that was caused in the past; the present environmental pollution associated with the existing mining facility; future environmental costs.The study shows that the design of the mining facilities shall be based on the assessment of possible environmental impacts and effectiveness of environmental protection measures. In this regard, the economic assessment of environmental damage in the mining design of the object should represent a combination of costs of implementing environmental measures to compensate for residual environmental impacts and reclamation of disturbed natural complexes.

New concept of damage evaluation method for core internal materials considering radiation induced stress relaxation (1). Experiments and modeling of radiation effects

International Nuclear Information System (INIS)

Miwa, Yukio; Kondo, Keietsu; Okubo, Nariaki; Kaji, Yoshiyuki; Tsukada, Takashi

2009-01-01

In order to build the new concept of material damage evaluation method, synergistic effect of radiation and residual stress on material degradation was estimated experimentally, and the effect of radiation induced stress relaxation on retardation of material degradation was observed. (author)

TEGANGAN RESIDU KEPING ARESTER SEBAGAI FUNGSI DARI CACAH KEPING ARESTER

Directory of Open Access Journals (Sweden)

Devia Eka Yunida dan T. Haryono

2014-06-01

Full Text Available Indonesia is a tropical area with a high intensity of repeating lightning strikes. The voltage is produced by lightning by increasing the presence of sensitive loads. Therefore, lightning can easily worsen the quality of consumer power, even if the generated voltage is relatively low. Lightning strikes can cause excessive voltage along the power lines. Its propagation can cause a voltage surge on low voltage systems, which can damage the equipment. Maintenance and protection against lightning strikes are necessary for the prevention of such damage. Arrester is a device that is intensively used nowadays by the general public to protect equipments from lightning strikes. It is used to protect the system from the danger of lightning by flowing current into the ground and leaving a certain resistance value, so that the system does not experience a surge voltage.This research was conducted through laboratory-scale testings using several major equipments, such as a high voltage generator, an impulse voltage generator, and an oscilloscope. Modifications of the tests were done using one to four 220 volt low voltage Merlin Gerin LTD arresters arranged in series, with a maximum current of 6.5 kA . Calculations using equations for low voltage circuit in series were done for more than four arresters. From the test results, it was found that the characteristics of the arrester residual voltage will rise when connected in series. Low voltage arresters can be used for higher voltage requirements by counting the number of arresters needed. The equation for the number of arresters in series required to cut the overvoltage surge is y = 0.694x – 0.106. Therefore, if more than 4 arresters will be needed, the residue voltage can be estimated through this formula.

X-ray diffraction study of microstructural changes during fatigue damage initiation in pipe steels: Role of the initial dislocation structure

International Nuclear Information System (INIS)

Pinheiro, B.; Lesage, J.; Pasqualino, I.; Bemporad, E.; Benseddiq, N.

2013-01-01

The present work is the second part of an ongoing study of microstructural changes during fatigue damage initiation in pipe steels [B. Pinheiro et al., Mat. Sci. Eng., A 532 (2012) 158–166]. Microdeformations and residual stresses (macrostresses) are evaluated by X-ray diffraction during alternating bending fatigue tests on samples taken from an API 5L X60 grade steel pipe. Microdeformations are evaluated from the full width at half maximum (FWHM) of the diffraction peak and residual stresses are estimated from the peak shift. Here, to understand the role of the initial dislocation structure, annealed samples are considered. As previously found for as-machined samples, the evolution of microdeformations shows three regular successive stages, but now with an increase during the first stage. The amplitude of each stage is accentuated with increasing stress amplitude, while its duration is reduced. Residual stresses show a similar trend, with stages of the same durations than those observed for FWHM, respectively. Additionally, changes in density and distribution of dislocations are observed by transmission electron microscopy combined with the technique of focused ion beam. The results are very encouraging for the development of a future indicator of fatigue damage initiation for pipe steels based on microstructural changes measured by X-ray diffraction

X-ray diffraction study of microstructural changes during fatigue damage initiation in pipe steels: Role of the initial dislocation structure

Energy Technology Data Exchange (ETDEWEB)

Pinheiro, B., E-mail: bianca@lts.coppe.ufrj.br [Laboratory of Mechanics of Lille (LML), UMR CNRS 8107, University Lille 1, Boulevard Paul Langevin, Cité Scientifique, 59655 Villeneuve d' Ascq (France); Lesage, J. [Laboratory of Mechanics of Lille (LML), UMR CNRS 8107, University Lille 1, Boulevard Paul Langevin, Cité Scientifique, 59655 Villeneuve d' Ascq (France); Pasqualino, I. [Subsea Technology Laboratory (LTS), Ocean Engineering Department, COPPE/Federal University of Rio de Janeiro, PO Box 68508, Cidade Universitária, CEP 21945-970, Rio de Janeiro/RJ (Brazil); Bemporad, E. [University of Rome “ROMA TRE”, Mechanical and Industrial Eng. Dept., Via Vasca Navale 79, 00146 Rome (Italy); Benseddiq, N. [Laboratory of Mechanics of Lille (LML), UMR CNRS 8107, University Lille 1, Boulevard Paul Langevin, Cité Scientifique, 59655 Villeneuve d' Ascq (France)

2013-09-15

The present work is the second part of an ongoing study of microstructural changes during fatigue damage initiation in pipe steels [B. Pinheiro et al., Mat. Sci. Eng., A 532 (2012) 158–166]. Microdeformations and residual stresses (macrostresses) are evaluated by X-ray diffraction during alternating bending fatigue tests on samples taken from an API 5L X60 grade steel pipe. Microdeformations are evaluated from the full width at half maximum (FWHM) of the diffraction peak and residual stresses are estimated from the peak shift. Here, to understand the role of the initial dislocation structure, annealed samples are considered. As previously found for as-machined samples, the evolution of microdeformations shows three regular successive stages, but now with an increase during the first stage. The amplitude of each stage is accentuated with increasing stress amplitude, while its duration is reduced. Residual stresses show a similar trend, with stages of the same durations than those observed for FWHM, respectively. Additionally, changes in density and distribution of dislocations are observed by transmission electron microscopy combined with the technique of focused ion beam. The results are very encouraging for the development of a future indicator of fatigue damage initiation for pipe steels based on microstructural changes measured by X-ray diffraction.

Enzymatic recognition of DNA damage induced by UVB-photosensitized titanium dioxide and biological consequences in Saccharomyces cerevisiae: evidence for oxidatively DNA damage generation.

Science.gov (United States)

Pinto, A Viviana; Deodato, Elder L; Cardoso, Janine S; Oliveira, Eliza F; Machado, Sérgio L; Toma, Helena K; Leitão, Alvaro C; de Pádula, Marcelo

2010-06-01

Although titanium dioxide (TiO(2)) has been considered to be biologically inert, finding use in cosmetics, paints and food colorants, recent reports have demonstrated that when TiO(2) is attained by UVA radiation oxidative genotoxic and cytotoxic effects are observed in living cells. However, data concerning TiO(2)-UVB association is poor, even if UVB radiation represents a major environmental carcinogen. Herein, we investigated DNA damage, repair and mutagenesis induced by TiO(2) associated with UVB irradiation in vitro and in vivo using Saccharomyces cerevisiae model. It was found that TiO(2) plus UVB treatment in plasmid pUC18 generated, in addition to cyclobutane pyrimidine dimers (CPDs), specific damage to guanine residues, such as 8-oxo-7,8-dihydroguanine (8-oxoG) and 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG), which are characteristic oxidatively generated lesions. In vivo experiments showed that, although the presence of TiO(2) protects yeast cells from UVB cytotoxicity, high mutation frequencies are observed in the wild-type (WT) and in an ogg1 strain (deficient in 8-oxoG and FapyG repair). Indeed, after TiO(2) plus UVB treatment, induced mutagenesis was drastically enhanced in ogg1 cells, indicating that mutagenic DNA lesions are repaired by the Ogg1 protein. This effect could be attenuated by the presence of metallic ion chelators: neocuproine or dipyridyl, which partially block oxidatively generated damage occurring via Fenton reactions. Altogether, the results indicate that TiO(2) plus UVB potentates UVB oxidatively generated damage to DNA, possibly via Fenton reactions involving the production of DNA base damage, such as 8-oxo-7,8-dihydroguanine. Copyright 2010 Elsevier B.V. All rights reserved.

Enzymatic recognition of DNA damage induced by UVB-photosensitized titanium dioxide and biological consequences in Saccharomyces cerevisiae: Evidence for oxidatively DNA damage generation

Energy Technology Data Exchange (ETDEWEB)

Pinto, A. Viviana, E-mail: alicia.pinto@incqs.fiocruz.br [Laboratorio de Diagnostico Molecular e Hematologia, Faculdade de Farmacia, Universidade Federal do Rio de Janeiro, Centro de Ciencias da Saude - Ilha do Fundao, CEP 21941-540, Rio de Janeiro (Brazil); Laboratorio de Radiobiologia Molecular, Instituto de Biofisica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Centro de Ciencias da Saude - Ilha do Fundao, CEP 21949-900, Rio de Janeiro (Brazil); Deodato, Elder L. [Laboratorio de Diagnostico Molecular e Hematologia, Faculdade de Farmacia, Universidade Federal do Rio de Janeiro, Centro de Ciencias da Saude - Ilha do Fundao, CEP 21941-540, Rio de Janeiro (Brazil); Laboratorio de Radiobiologia Molecular, Instituto de Biofisica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Centro de Ciencias da Saude - Ilha do Fundao, CEP 21949-900, Rio de Janeiro (Brazil); Cardoso, Janine S. [Laboratorio de Radiobiologia Molecular, Instituto de Biofisica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Centro de Ciencias da Saude - Ilha do Fundao, CEP 21949-900, Rio de Janeiro (Brazil); Oliveira, Eliza F.; Machado, Sergio L.; Toma, Helena K. [Laboratorio de Diagnostico Molecular e Hematologia, Faculdade de Farmacia, Universidade Federal do Rio de Janeiro, Centro de Ciencias da Saude - Ilha do Fundao, CEP 21941-540, Rio de Janeiro (Brazil); Leitao, Alvaro C. [Laboratorio de Radiobiologia Molecular, Instituto de Biofisica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Centro de Ciencias da Saude - Ilha do Fundao, CEP 21949-900, Rio de Janeiro (Brazil); Padula, Marcelo de [Laboratorio de Diagnostico Molecular e Hematologia, Faculdade de Farmacia, Universidade Federal do Rio de Janeiro, Centro de Ciencias da Saude - Ilha do Fundao, CEP 21941-540, Rio de Janeiro (Brazil)

2010-06-01

Although titanium dioxide (TiO{sub 2}) has been considered to be biologically inert, finding use in cosmetics, paints and food colorants, recent reports have demonstrated that when TiO{sub 2} is attained by UVA radiation oxidative genotoxic and cytotoxic effects are observed in living cells. However, data concerning TiO{sub 2}-UVB association is poor, even if UVB radiation represents a major environmental carcinogen. Herein, we investigated DNA damage, repair and mutagenesis induced by TiO{sub 2} associated with UVB irradiation in vitro and in vivo using Saccharomyces cerevisiae model. It was found that TiO{sub 2} plus UVB treatment in plasmid pUC18 generated, in addition to cyclobutane pyrimidine dimers (CPDs), specific damage to guanine residues, such as 8-oxo-7,8-dihydroguanine (8-oxoG) and 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG), which are characteristic oxidatively generated lesions. In vivo experiments showed that, although the presence of TiO{sub 2} protects yeast cells from UVB cytotoxicity, high mutation frequencies are observed in the wild-type (WT) and in an ogg1 strain (deficient in 8-oxoG and FapyG repair). Indeed, after TiO{sub 2} plus UVB treatment, induced mutagenesis was drastically enhanced in ogg1 cells, indicating that mutagenic DNA lesions are repaired by the Ogg1 protein. This effect could be attenuated by the presence of metallic ion chelators: neocuproine or dipyridyl, which partially block oxidatively generated damage occurring via Fenton reactions. Altogether, the results indicate that TiO{sub 2} plus UVB potentates UVB oxidatively generated damage to DNA, possibly via Fenton reactions involving the production of DNA base damage, such as 8-oxo-7,8-dihydroguanine.

Evaluation of residue-residue contact prediction in CASP10

KAUST Repository

Monastyrskyy, Bohdan

2013-08-31

We present the results of the assessment of the intramolecular residue-residue contact predictions from 26 prediction groups participating in the 10th round of the CASP experiment. The most recently developed direct coupling analysis methods did not take part in the experiment likely because they require a very deep sequence alignment not available for any of the 114 CASP10 targets. The performance of contact prediction methods was evaluated with the measures used in previous CASPs (i.e., prediction accuracy and the difference between the distribution of the predicted contacts and that of all pairs of residues in the target protein), as well as new measures, such as the Matthews correlation coefficient, the area under the precision-recall curve and the ranks of the first correctly and incorrectly predicted contact. We also evaluated the ability to detect interdomain contacts and tested whether the difficulty of predicting contacts depends upon the protein length and the depth of the family sequence alignment. The analyses were carried out on the target domains for which structural homologs did not exist or were difficult to identify. The evaluation was performed for all types of contacts (short, medium, and long-range), with emphasis placed on long-range contacts, i.e. those involving residues separated by at least 24 residues along the sequence. The assessment suggests that the best CASP10 contact prediction methods perform at approximately the same level, and comparably to those participating in CASP9.

Structural and mutational analysis of Escherichia coli AlkB provides insight into substrate specificity and DNA damage searching.

Directory of Open Access Journals (Sweden)

Paul J Holland

Full Text Available BACKGROUND: In Escherichia coli, cytotoxic DNA methyl lesions on the N1 position of purines and N3 position of pyrimidines are primarily repaired by the 2-oxoglutarate (2-OG iron(II dependent dioxygenase, AlkB. AlkB repairs 1-methyladenine (1-meA and 3-methylcytosine (3-meC lesions, but it also repairs 1-methylguanine (1-meG and 3-methylthymine (3-meT at a much less efficient rate. How the AlkB enzyme is able to locate and identify methylated bases in ssDNA has remained an open question. METHODOLOGY/PRINCIPAL FINDINGS: We determined the crystal structures of the E. coli AlkB protein holoenzyme and the AlkB-ssDNA complex containing a 1-meG lesion. We coupled this to site-directed mutagenesis of amino acids in and around the active site, and tested the effects of these mutations on the ability of the protein to bind both damaged and undamaged DNA, as well as catalyze repair of a methylated substrate. CONCLUSIONS/SIGNIFICANCE: A comparison of our substrate-bound AlkB-ssDNA complex with our unliganded holoenzyme reveals conformational changes of residues within the active site that are important for binding damaged bases. Site-directed mutagenesis of these residues reveals novel insight into their roles in DNA damage recognition and repair. Our data support a model that the AlkB protein utilizes at least two distinct conformations in searching and binding methylated bases within DNA: a "searching" mode and "repair" mode. Moreover, we are able to functionally separate these modes through mutagenesis of residues that affect one or the other binding state. Finally, our mutagenesis experiments show that amino acid D135 of AlkB participates in both substrate specificity and catalysis.

Damage Assessment in a SiC-fiber reinforced Ceramic Matrix Composite

Directory of Open Access Journals (Sweden)

Konstantinos G. Dassios

2013-01-01

Full Text Available Assessment of the fracture behavior of a SiC-fbre-reinforced barium osumilite (BMAS ceramic matrix composite tested under static and cyclic tension conditions is reported herein. Notched specimens were used in order to limit material damage within a predefined gauge length. Imposition of successive unloading/reloading loops was found to result in an increase by 20% in material strength as compared to pure tension; the observed increase is attributed to energy dissipation from large-scale interfacial debonding phenomena that dominated the post-elastic tensile behaviour of the composite. Cyclic loading also helped establish the axial residual stress state of the fibres in the composite of tensile nature via a well-defined common intersection point of unloading-reloading cycles. A translation vector approach in the stress-strain plane was successful in establishing the residual stress-free properties of the composite and in reconciling the scatter noted in elastic properties of specimens with respect to theoretical expectations.

Proceedings of the 7. biennial residue-to-revenue residual wood conference 2007

International Nuclear Information System (INIS)

Raulin, J.

2007-01-01

This conference provided information on the highest and best use of residual wood, which is quickly becoming a valuable commodity. Issues concerning forest residues, sawmill wastes, agricultural residues and urban organic materials were discussed along with trends in Canadian surplus mill waste production. The evolving nature and technologies of the biomass business were highlighted with particular focus on how to generate energy and save money through the use of residual wood. Residual wood energy projects and developments in Canada, North America and Europe were outlined along with biomass development in relation to forest fires and insect disturbances. Cogeneration technologies using wood wastes for thermal heat, steam and electricity were also presented, along with transportation fuel technologies for the production of ethanol. It was noted that with the rising cost of energy, the forest industry is seeking energy solutions based on the use of residual wood. The range of economically practical residual wood solutions continues to grow as energy prices increase. The conference was attended by more than 200 delegates from the forest industry, suppliers and government representatives, to discuss policies and procedures currently in place. Industry investment is being stimulated by the potential for biofuels and biochemicals, as well as the co-operation between the forest and energy sectors. The conference featured 23 presentations, of which 12 have been catalogued separately for inclusion in this database. refs., tabs., figs

Developing Dynamic Digital Image Correlation Technique to Monitor Structural Damage of Old Buildings under External Excitation

Directory of Open Access Journals (Sweden)

Ming-Hsiang Shih

2014-01-01

Full Text Available The capacity of buildings to resist external excitation is an important factor to consider for the structural design of buildings. When subject to external excitation, a building may suffer a certain degree of damages, and its residual capacity to resist external excitation cannot be evaluated. In this research, dynamic digital image correlation method combined with parameter evaluation available in system identification is used to evaluate the structural capacity to resist external excitation. The results reveal possible building latent safety problems so that timely structural reinforcement or dismantling of the building can be initiated to alleviate further damages. The results of experiments using the proposed method conform to the results obtained using the conventional method, but this method is more convenient and rapid than the latter in the subsequent procedure of data processing. If only the frequency change is used, the damages suffered by the building can be detected, but the damage location is not revealed. The interstory drift mode shape (IDMS based on the characteristic of story drift has higher sensitivity than the approximate story damage index (ADSI method based on modal frequency and vibration type; however, both indices can be used to determine the degree and location of building damages.

Selective Removal of Residual Orthodontic Composite Using a Rapidly Scanned Carbon Dioxide Laser with Spectral Feedback

Science.gov (United States)

Hirasuna, Krista

Background and Objective: Excessive heat accumulation within the tooth, incomplete removal of composite, and variable damage to the enamel are shortcomings of using conventional burs to remove residual orthodontic composite after debonding fixed appliances. The objective of this study was to determine if composite could be selectively removed from the enamel surface using a rapidly scanned carbon dioxide laser controlled by spectral feedback. Materials and Methods: A carbon dioxide laser operating at a wavelength of 9.3 microm with a pulse duration of 10-15 micros and a pulse repetition rate of ˜ 200 Hz was used to selectively remove composite from the buccal surfaces of 21 extracted teeth. GrenGloo(TM) composite was used to better visualize residual composite and the amount of enamel lost was measured with optical microscopy. A spectral feedback system utilizing a miniature spectrometer was used to control the laser scanning system. Pulpal temperature measurements were performed during composite removal to determine if there was excessive heat accumulation. Results: The amount of enamel lost averaged 22.7microm +/- 8.9 and 25.3 microm +/- 9.4 for removal at 3.8 and 4.2 J/cm2, respectively. An average maximum temperature rise of 1.9°C +/- 1.5 was recorded, with no teeth approaching the critical value of 5.5°C. The average time of composite removal was 19.3 +/- 4.1 seconds. Conclusions: Residual orthodontic composite can be rapidly removed from the tooth surface using a rapidly scanned CO2 laser with spectral feedback, with minimal temperature rise within the pulp and with minimal damage to the underlying enamel surface.

Damage pattern as a function of radiation quality and other factors.

Science.gov (United States)

Burkart, W; Jung, T; Frasch, G

1999-01-01

An understanding of damage pattern in critical cellular structures such as DNA is an important prerequisite for a mechanistic assessment of primary radiation damage, its possible repair, and the propagation of residual changes in somatic and germ cells as potential contributors to disease or ageing. Important quantitative insights have been made recently on the distribution in time and space of critical lesions from direct and indirect action of ionizing radiation on mammalian cells. When compared to damage from chemicals or from spontaneous degradation, e.g. depurination or base deamination in DNA, the potential of even low-LET radiation to create local hot spots of damage from single particle tracks is of utmost importance. This has important repercussions on inferences from critical biological effects at high dose and dose rate exposure situations to health risks at chronic, low-level exposures as experienced in environmental and controlled occupational settings. About 10,000 DNA lesions per human cell nucleus and day from spontaneous degradation and chemical attack cause no apparent effect, but a dose of 4 Gy translating into a similar number of direct and indirect DNA breaks induces acute lethality. Therefore, single lesions cannot explain the high efficiency of ionizing radiation in the induction of mutation, transformation and loss of proliferative capacity. Clustered damage leading to poorly repairable double-strand breaks or even more complex local DNA degradation, correlates better with fixed damage and critical biological endpoints. A comparison with other physical, chemical and biological agents indicates that ionizing radiation is indeed set apart from these by its unique micro- and nano-dosimetric traits. Only a few other agents such as bleomycin have a similar potential to cause complex damage from single events. However, in view of the multi-stage mechanism of carcinogenesis, it is still an open question whether dose-effect linearity for complex

Probabilistic residual life assessment of high temperature pipings in nuclear power plants against creep fatigue damage: final report

International Nuclear Information System (INIS)

Gupta, Sanjay

2014-02-01

Residual life assessment of components of nuclear power plants is essential for their operational safety, reliability and financial viability. The high risks involved in the event of failures in nuclear power plants have led to the development of design philosophies that incorporate extreme conservatism in design. The implications of such conservatism in design leads to more frequent maintenance operations than necessary

Evaluating Variability and Uncertainty of Geological Strength Index at a Specific Site

Science.gov (United States)

Wang, Yu; Aladejare, Adeyemi Emman

2016-09-01

Geological Strength Index (GSI) is an important parameter for estimating rock mass properties. GSI can be estimated from quantitative GSI chart, as an alternative to the direct observational method which requires vast geological experience of rock. GSI chart was developed from past observations and engineering experience, with either empiricism or some theoretical simplifications. The GSI chart thereby contains model uncertainty which arises from its development. The presence of such model uncertainty affects the GSI estimated from GSI chart at a specific site; it is, therefore, imperative to quantify and incorporate the model uncertainty during GSI estimation from the GSI chart. A major challenge for quantifying the GSI chart model uncertainty is a lack of the original datasets that have been used to develop the GSI chart, since the GSI chart was developed from past experience without referring to specific datasets. This paper intends to tackle this problem by developing a Bayesian approach for quantifying the model uncertainty in GSI chart when using it to estimate GSI at a specific site. The model uncertainty in the GSI chart and the inherent spatial variability in GSI are modeled explicitly in the Bayesian approach. The Bayesian approach generates equivalent samples of GSI from the integrated knowledge of GSI chart, prior knowledge and observation data available from site investigation. Equations are derived for the Bayesian approach, and the proposed approach is illustrated using data from a drill and blast tunnel project. The proposed approach effectively tackles the problem of how to quantify the model uncertainty that arises from using GSI chart for characterization of site-specific GSI in a transparent manner.

Identification of Soil Properties and Organophosphate Residues From Agricultural Land in Wanasari Sub-District, Brebes, Indonesia

Science.gov (United States)

Joko, Tri; Anggoro, Sutrisno; Sunoko, Henna Rya; Rachmawati, Savitri

2018-02-01

Organophosphates have been used to eradicate pests and prevent losses from harvest failures caused by pest attack. It is undeniable that the organophosphate persist in soil. This study aims to identify the organophosphate residue and soil properties include pH, soil texture, and permeability. The soil samples were taken from cropland in 10 villages, Wanasari sub-district, Brebes, Indonesia. Organophosphate residue determined by gas chromatography using Flame Photometric Detector. Soil texture was determined by soil texture triangle from NRCS USDA, and the permeability value was determined by falling head method. The mean value of chlorpyrifos, profenofos, diazinon were 0.0078; 0.0388; 0.2271 mg/l respectively. The soil texture varies from clay, silt clay, loam, silt loam, and silt clay loam with permeability value at 10-7 with the soil pH value between 6.4 - 8.1. The results showed that organophosphate residues found in the soil and its potential affect the soil fertility decline. We recommend to conduct routine soil quality analysis to prevent soil damage in the agricultural environment.

Measurement of adherence of residually stressed thin films by indentation. I. Mechanics of interface delamination

International Nuclear Information System (INIS)

Marshall, D.B.; Evans, A.G.

1984-01-01

A fracture analysis of indentation-induced delamination of thin films is presented. The analysis is based on a model system in which the section of film above the delaminating crack is treated as a rigidly clamped disc, and the crack extension force is derived from changes in strain energy of the system as the crack extends. Residual deposition stresses influence the cracking response by inducing buckling of the film above the crack and by providing an additional crack driving force once buckling occurs. A relation for the equilibrium crack length is derived in terms of the indenter load and geometry, the film thickness and mechanical properties, the residual stress level and the fracture toughness of the interface. The analysis provides a basis for using controlled indentation cracking as a quantitative measure of interface toughness and for evaluating contact-induced damage in thin films

A correlation between residual radiation-induced DNA double-strand breaks in cultured fibroblasts and late radiotherapy reactions in breast cancer patients

International Nuclear Information System (INIS)

Kiltie, A.E.; Ryan, A.J.; Swindell, R.; Barber, J.B.P.; West, C.M.L.; Magee, B.; Hendry, J.H.

1999-01-01

Background and purpose: Prediction of late normal tissue reactions to radiotherapy would permit tailoring of dosage to each patient. Measurement of residual DNA double strand breaks using pulsed field gel electrophoresis (PFGE) shows promise in this field. The aim of this study was to test the predictive potential of PFGE in a group of retrospectively studied breast cancer patients.Materials and methods: Thirty nine patients, treated uniformly for breast cancer 9-15 years previously, with excision of the tumour and radiotherapy to the breast and drainage areas, were assessed clinically using the LENT SOMA scale, and a 5-mm punch biopsy taken from the buttock. Fibroblast cell strains were established and used to study residual DNA double strand breaks, using PFGE.Results: There were significant correlations between the DNA assay results and the fibrosis score (r s =0.46; P=0.003), the combined fibrosis and retraction score (r s =0.45, P=0.004) and the overall LENT score (r s =0.43; P=0.006). Using polychotomous logistic regression, the fibroblast DNA assay result was an independent prognostic factor for fibrosis severity.Conclusions: There is a relationship between residual radiation-induced DNA damage in fibroblasts and the severity of the late normal tissue damage seen in the patients from whom the cells were cultured. (Copyright (c) 1999 Elsevier Science B.V., Amsterdam. All rights reserved.)

Solid residues

International Nuclear Information System (INIS)

Mulder, E.; Duin, P.J. van; Grootenboer, G.J.

1995-01-01

A summary is presented of the many investigations that have been done on solid residues of atmospheric fluid bed combustion (AFBC). These residues are bed ash, cyclone ash and bag filter ash. Physical and chemical properties are discussed and then the various uses of residues (in fillers, bricks, gravel, and for recovery of aluminium) are summarised. Toxicological properties of fly ash and stack ash are discussed as are risks of pneumoconiosis for workers handling fly ash, and contamination of water by ashes. On the basis of present information it is concluded that risks to public health from exposure to emissions of coal fly ash from AFBC appear small or negligible as are health risk to workers in the coal fly ash processing industry. 35 refs., 5 figs., 12 tabs

Contribution to the design, fulfillment, and data analysis of fission fragment yields of the SOFIA experiment at GSI

International Nuclear Information System (INIS)

Pellereau, Eric

2013-01-01

The isotopic fission yields of U 238 following the SOFIA experiment, conducted at the GSI facility (Darmstadt), are presented here. This experiment takes advantage of the inverse kinematics technique at relativistic energies. Benefits are several: fission fragments are highly focused (high geometrical efficiency) and are also completely stripped, which greatly simplifies their nuclear charge measurement. The first detector of the SOFIA setup is an active target in which fission occurs via electromagnetic excitation, followed by an ionization chamber to measure the nuclear charge and the horizontal angle of both fission fragments. The masses are deduced by the bending radius measurement of the fragments, deflected by a strong magnet (ALADIN), thanks to two position detectors (MWPC), and also by a highly resolved time-of-flight measurement (40 ps FWHM) so that heavy neighboring isotopes can be separated. The data analysis shows that the main goals are achieved since the isotopic separation is reached over the whole range of the fission fragments. A strong even-odd effect is seen in the charge spectrum, which also exhibits a mean heavy charge close to Z = 54. Surprisingly, the neutron even-odd effect of the light region is seen to be very close to the one in thermal neutron induced fission. The peak-to-valley ratio of the mass spectrum confirms that the mean excitation energy at fission is close to the expected one (14 MeV). The GEF code is used for comparison and always gives results very close to ours. (author) [fr

New results from isochronous mass measurements of neutron-rich uranium fission fragments with the FRS-ESR-facility at GSI

Energy Technology Data Exchange (ETDEWEB)

Knoebel, R.; Litvinov, Yu.A.; Weick, H.; Bosch, F.; Boutin, D.; Dimopoulou, C.; Dolinskii, A.; Franczak, B.; Franzke, B.; Kozhuharov, C.; Kurcewicz, J.; Litvinov, S.A.; Matos, M.; Mazzocco, M.; Muenzenberg, G.; Nociforo, C.; Nolden, F.; Stadlmann, J.; Steck, M.; Winkler, M. [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Diwisch, M. [Justus-Liebig-Universitaet Giessen, II. Physikalisches Institut, Giessen (Germany); Geissel, H.; Plass, W.R.; Scheidenberger, C.; Chen, L. [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Justus-Liebig-Universitaet Giessen, II. Physikalisches Institut, Giessen (Germany); Patyk, Z. [National Centre for Nuclear Research - NCBJ Swierk, Warszawa (Poland); Sun, B. [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Beihang University, School of Physics and Nuclear Energy Engineering, Beijing (China); Hausmann, M. [Michigan State University, East Lansing, MI (United States); Nakajima, S.; Suzuki, T.; Yamaguchi, T. [Saitama University, Department of Physics, Saitama (Japan); Ohtsubo, T. [Niigata University, Department of Physics, Niigata (Japan); Ozawa, A. [University of Tsukuba, Institute of Physics, Ibaraki (Japan); Walker, P.M. [University of Surrey, Department of Physics, Guildford (United Kingdom)

2016-05-15

Masses of uranium fission fragments have been measured with the FRagment Separator (FRS) combined with the Experimental Storage Ring (ESR) at GSI. A 410-415 MeV/u {sup 238}U projectile beam was fast extracted from the synchrotron SIS-18 with an average intensity of 10{sup 9}/spill. The projectiles were focused on a 1g/cm{sup 2} beryllium target at the entrance of the FRS to create neutron-rich isotopes via abrasion-fission. The fission fragments were spatially separated with the FRS and injected into the isochronous storage ring ESR for fast mass measurements without applying cooling. The Isochronous Mass Spectrometry (IMS) was performed under two different experimental conditions, with and without B ρ-tagging at the high-resolution dispersive central focal plane of the FRS. The evaluation has been done for the combined data sets from both experiments with a new method of data analysis. The use of a correlation matrix has provided experimental mass values for 23 different neutron-rich isotopes for the first time and 6 masses with improved values. The new masses were obtained for nuclides in the element range from Se to Ce. The applied analysis has given access even to rare isotopes detected with an intensity of a few atoms per week. The novel data analysis and systematic error determination are described and the results are compared with extrapolations of experimental values and theoretical models. (orig.)

Histone peptide AKRHRK enhances H2O2-induced DNA damage and alters its site specificity

International Nuclear Information System (INIS)

Midorikawa, Kaoru; Murata, Mariko; Kawanishi, Shosuke

2005-01-01

Histone proteins are involved in compaction of DNA and the protection of cells from oxygen toxicity. However, several studies have demonstrated that the metal-binding histone reacts with H 2 O 2 , leading to oxidative damage to a nucleobase. We investigated whether histone can accelerate oxidative DNA damage, using a minimal model for the N-terminal tail of histone H4, CH 3 CO-AKRHRK-CONH 2 , which has a metal-binding site. This histone peptide enhanced DNA damage induced by H 2 O 2 and Cu(II), especially at cytosine residues, and induced additional DNA cleavage at the 5'-guanine of GGG sequences. The peptide also enhanced the formation of 8-oxo-7,8-dihydro-2'-deoxyguanosine and ESR spin-trapping signal from H 2 O 2 and Cu(II). Cyclic redox reactions involving histone-bound Cu(II) and H 2 O 2 , may give rise to multiple production of radicals leading to multiple hits in DNA. It is noteworthy that the histone H4 peptide with specific sequence AKRHRK can cause DNA damage rather than protection under metal-overloaded condition

An estimation of core damage frequency of a pressurized water reactor during mid-loop operation

International Nuclear Information System (INIS)

Chao, C.C.; Chen, C.T.; Lee, M.

2004-01-01

The core damage frequency during mid-loop operation of a Westinghouse designed 3-loop Pressurizer Water Reactor (PWR) due to loss of Residual Heat Removal (RHR) events was assessed. The assessment considers two types of outages (refueling and drained maintenance), and uses failure data collected specifically for shutdown condition. Event trees were developed for five categories of loss of RHR events. Human actions to mitigate the loss of RHR events was identified and human error probabilities were quantified using HCR and THERP model. The result showed that the core damage frequency due to loss of RHR events during mid-loop operation is 3.1x10 -5 per year. The results also showed that the core damage frequency can be reduced significantly by removing a pressurizer safety valve before entering mid-loop operation. The establishment of reflux cooling, i.e. decay heat removal through steam generator secondary side also plays important role in mitigating the loss of RHR events. (author)

A family of metal-dependent phosphatases implicated in metabolite damage-control

Energy Technology Data Exchange (ETDEWEB)

Huang, Lili; Khusnutdinova, Anna; Nocek, Boguslaw; Brown, Greg; Xu, Xiaohui; Cui, Hong; Petit, Pierre; Flick, Robert; Zallot, Rémi; Balmant, Kelly; Ziemak, Michael J.; Shanklin, John; de Crécy-Lagard, Valérie; Fiehn, Oliver; Gregory, Jesse F.; Joachimiak, Andrzej; Savchenko, Alexei; Yakunin, Alexander F.; Hanson, Andrew D.

2016-06-20

DUF89 family proteins occur widely in both prokaryotes and eukaryotes, but their functions are unknown. Here we define three DUF89 subfamilies (I, II, and III), with subfamily II being split into stand-alone proteins and proteins fused to pantothenate kinase (PanK). We demonstrated that DUF89 proteins have metal-dependent phosphatase activity against reactive phosphoesters or their damaged forms, notably sugar phosphates (subfamilies II and III), phosphopantetheine and its S-sulfonate or sulfonate (subfamily II-PanK fusions), and nucleotides (subfamily I). Genetic and comparative genomic data strongly associated DUF89 genes with phosphoester metabolism. The crystal structure of the yeast (Saccharomyces cerevisiae) subfamily III protein YMR027W revealed a novel phosphatase active site with fructose 6-phosphate and Mg2+ bound near conserved signature residues Asp254 and Asn255 that are critical for activity. These findings indicate that DUF89 proteins are previously unrecognized hydrolases whose characteristic in vivo function is to limit potentially harmful buildups of normal or damaged phosphometabolites.

Damage Tolerant Analysis of Cracked Al 2024-T3 Panels repaired with Single Boron/Epoxy Patch

Science.gov (United States)

Mahajan, Akshay D.; Murthy, A. Ramachandra; Nanda Kumar, M. R.; Gopinath, Smitha

2018-06-01

It is known that damage tolerant analysis has two objectives, namely, remaining life prediction and residual strength evaluation. To achieve the these objectives, determination of accurate and reliable fracture parameter is very important. XFEM methodologies for fatigue and fracture analysis of cracked aluminium panels repaired with different patch shapes made of single boron/epoxy have been developed. Heaviside and asymptotic crack tip enrichment functions are employed to model the crack. XFEM formulations such as displacement field formulation and element stiffness matrix formulation are presented. Domain form of interaction integral is employed to determine Stress Intensity Factor of repaired cracked panels. Computed SIFs are incorporated in Paris crack growth model to predict the remaining fatigue life. The residual strength has been computed by using the remaining life approach, which accounts for both crack growth constants and no. of cycles to failure. From the various studies conducted, it is observed that repaired panels have significant effect on reduction of the SIF at the crack tip and hence residual strength as well as remaining life of the patched cracked panels are improved significantly. The predicted remaining life and residual strength will be useful for design of structures/components under fatigue loading.

Damage detection in high-rise buildings using damage-induced rotations

International Nuclear Information System (INIS)

Sung, Seung Hun; Jung, Ho Youn; Lee, Jung Hoon; Jung, Hyung Jo

2016-01-01

In this paper, a new damage-detection method based on structural vibration is proposed. The essence of the proposed method is the detection of abrupt changes in rotation. Damage-induced rotation (DIR), which is determined from the modal flexibility of the structure, initially occurs only at a specific damaged location. Therefore, damage can be localized by evaluating abrupt changes in rotation. We conducted numerical simulations of two damage scenarios using a 10-story cantilever-type building model. Measurement noise was also considered in the simulation. We compared the sensitivity of the proposed method to localize damage to that of two conventional modal-flexibility-based damage-detection methods, i.e., uniform load surface (ULS) and ULS curvature. The proposed method was able to localize damage in both damage scenarios for cantilever structures, but the conventional methods could not

Damage detection in high-rise buildings using damage-induced rotations

International Nuclear Information System (INIS)

Sung, Seung Hoon; Jung, Ho Youn; Lee, Jung Hoon; Jung, Hyung Jo

2014-01-01

In this paper, a new damage-detection method based on structural vibration is proposed. The essence of the proposed method is the detection of abrupt changes in rotation. Damage-induced rotation (DIR), which is determined from the modal flexibility of the structure, initially occurs only at a specific damaged location. Therefore, damage can be localized by evaluating abrupt changes in rotation. We conducted numerical simulations of two damage scenarios using a 10-story cantilever-type building model. Measurement noise was also considered in the simulation. We compared the sensitivity of the proposed method to localize damage to that of two conventional modal-flexibility-based damage-detection methods, i.e., uniform load surface (ULS) and ULS curvature. The proposed method was able to localize damage in both damage scenarios for cantilever structures, but the conventional methods could not.

Influence of cracks and pitting corrosion on residual ultimate strength of stiffened plates

Directory of Open Access Journals (Sweden)

ZHANG Jing

2018-02-01

Full Text Available [Objectives] Ships and offshore platforms serve in the harsh sea environment for a long time. Cracks and pitting corrosion will occur in such a structure and the damage will affect its ultimate strength.[Methods] To investigate the influence of cracks and pitting corrosion on ultimate bearing capacity, the ultimate strength of a structure under axial compression is studied by using a nonlinear finite element. The mesh size of a stiffened plate with cracks and pitting corrosion is first discussed. Then the influence of the relative positions of cracks and pitting corrosion, number of corrosion points and crack length impact on the residual ultimate strength of damaged stiffened plates is discussed via a series of calculations.[Results] The results indicate that the increase in crack length and pitting corrosion significantly decreases the ultimate strength of a stiffened plate. [Conclusions] This provides a useful reference for designing and maintaining ships and offshore structures in their life cycles.

Handling of Solid Residues

International Nuclear Information System (INIS)

Medina Bermudez, Clara Ines

1999-01-01

The topic of solid residues is specifically of great interest and concern for the authorities, institutions and community that identify in them a true threat against the human health and the atmosphere in the related with the aesthetic deterioration of the urban centers and of the natural landscape; in the proliferation of vectorial transmitters of illnesses and the effect on the biodiversity. Inside the wide spectrum of topics that they keep relationship with the environmental protection, the inadequate handling of solid residues and residues dangerous squatter an important line in the definition of political and practical environmentally sustainable. The industrial development and the population's growth have originated a continuous increase in the production of solid residues; of equal it forms, their composition day after day is more heterogeneous. The base for the good handling includes the appropriate intervention of the different stages of an integral administration of residues, which include the separation in the source, the gathering, the handling, the use, treatment, final disposition and the institutional organization of the administration. The topic of the dangerous residues generates more expectation. These residues understand from those of pathogen type that are generated in the establishments of health that of hospital attention, until those of combustible, inflammable type, explosive, radio-active, volatile, corrosive, reagent or toxic, associated to numerous industrial processes, common in our countries in development

Measurement of damage in systemic vasculitis: a comparison of the Vasculitis Damage Index with the Combined Damage Assessment Index

DEFF Research Database (Denmark)

Suppiah, Ravi; Flossman, Oliver; Mukhtyar, Chetan

2011-01-01

To compare the Vasculitis Damage Index (VDI) with the Combined Damage Assessment Index (CDA) as measures of damage from vasculitis.......To compare the Vasculitis Damage Index (VDI) with the Combined Damage Assessment Index (CDA) as measures of damage from vasculitis....

Rheological-dynamical continuum damage model for concrete under uniaxial compression and its experimental verification

Directory of Open Access Journals (Sweden)

Milašinović Dragan D.

2015-01-01

Full Text Available A new analytical model for the prediction of concrete response under uniaxial compression and its experimental verification is presented in this paper. The proposed approach, referred to as the rheological-dynamical continuum damage model, combines rheological-dynamical analogy and damage mechanics. Within the framework of this approach the key continuum parameters such as the creep coefficient, Poisson’s ratio and damage variable are functionally related. The critical values of the creep coefficient and damage variable under peak stress are used to describe the failure mode of the concrete cylinder. The ultimate strain is determined in the post-peak regime only, using the secant stress-strain relation from damage mechanics. The post-peak branch is used for the energy analysis. Experimental data for five concrete compositions were obtained during the examination presented herein. The principal difference between compressive failure and tensile fracture is that there is a residual stress in the specimens, which is a consequence of uniformly accelerated motion of load during the examination of compressive strength. The critical interpenetration displacements and crushing energy are obtained theoretically based on the concept of global failure analysis. [Projekat Ministarstva nauke Republike Srbije, br. ON 174027: Computational Mechanics in Structural Engineering i br. TR 36017: Utilization of by-products and recycled waste materials in concrete composites for sustainable construction development in Serbia: Investigation and environmental assessment of possible applications

Estimate of radiation damage to low-level electronics of the RF system in the LHC cavities arising from beam gas collisions.

Science.gov (United States)

Butterworth, A; Ferrari, A; Tsoulou, E; Vlachoudis, V; Wijnands, T

2005-01-01

Monte Carlo simulations have been performed to estimate the radiation damage induced by high-energy hadrons in the digital electronics of the RF low-level systems in the LHC cavities. High-energy hadrons are generated when the proton beams interact with the residual gas. The contributions from various elements-vacuum chambers, cryogenic cavities, wideband pickups and cryomodule beam tubes-have been considered individually, with each contribution depending on the gas composition and density. The probability of displacement damage and single event effects (mainly single event upsets) is derived for the LHC start-up conditions.

Interaction and sonodynamic damage activity of acridine red (AD-R) to bovine serum albumin (BSA)

Energy Technology Data Exchange (ETDEWEB)

Chen, Dandan; Xie, Jinhui; Wu, Qiong; Fan, Ping; Wang, Jun, E-mail: wangjun888tg@126.com

2015-04-15

The sonodynamic therapy (SDT) has become an attractive antitumor treatment method in recent years, but the selection of sonosensitizer, mechanism of damage biomolecule and kind of reactive oxygen species (ROS) generated during sonodynamic process have not been investigated in detail. In this paper, the acridine red (AD-R), as a sonosensitizer, combining with ultrasonic irradiation to damage bovine serum albumin (BSA) was investigated. At first, the interaction of AD-R to BSA molecules in aqueous solution was studied by fluorescence spectroscopy. As judged from the experimental results, the quenching mechanism of BSA fluorescence belongs to a static process. Synchronous fluorescence spectra demonstrate that the binding and damage sites to BSA molecules are mainly on the tryptophan residues. The generation and kind of generated ROS were also estimated by the method of oxidation and extraction photometry. This paper may offer some valuable references for the study of the sonodynamic activity and application of AD-R in SDT for tumor treatment. - Highlights: ●Acridine red (AD-R) is used to study interaction with BSA. ●Spectroscopy is used to study sonodynamic damage activity of AD-R to BSA. ●Generation of ROS caused by AD-R under ultrasonic irradiation was determined.

Interaction and sonodynamic damage activity of acridine red (AD-R) to bovine serum albumin (BSA)

International Nuclear Information System (INIS)

Chen, Dandan; Xie, Jinhui; Wu, Qiong; Fan, Ping; Wang, Jun

2015-01-01

The sonodynamic therapy (SDT) has become an attractive antitumor treatment method in recent years, but the selection of sonosensitizer, mechanism of damage biomolecule and kind of reactive oxygen species (ROS) generated during sonodynamic process have not been investigated in detail. In this paper, the acridine red (AD-R), as a sonosensitizer, combining with ultrasonic irradiation to damage bovine serum albumin (BSA) was investigated. At first, the interaction of AD-R to BSA molecules in aqueous solution was studied by fluorescence spectroscopy. As judged from the experimental results, the quenching mechanism of BSA fluorescence belongs to a static process. Synchronous fluorescence spectra demonstrate that the binding and damage sites to BSA molecules are mainly on the tryptophan residues. The generation and kind of generated ROS were also estimated by the method of oxidation and extraction photometry. This paper may offer some valuable references for the study of the sonodynamic activity and application of AD-R in SDT for tumor treatment. - Highlights: ●Acridine red (AD-R) is used to study interaction with BSA. ●Spectroscopy is used to study sonodynamic damage activity of AD-R to BSA. ●Generation of ROS caused by AD-R under ultrasonic irradiation was determined

Nondestructive damage detection and evaluation technique for seismically damaged structures

Science.gov (United States)

Adachi, Yukio; Unjoh, Shigeki; Kondoh, Masuo; Ohsumi, Michio

1999-02-01

The development of quantitative damage detection and evaluation technique, and damage detection technique for invisible damages of structures are required according to the lessons from the 1995 Hyogo-ken Nanbu earthquake. In this study, two quantitative damage sensing techniques for highway bridge structures are proposed. One method is to measure the change of vibration characteristics of the bridge structure. According to the damage detection test for damaged bridge column by shaking table test, this method can successfully detect the vibration characteristic change caused by damage progress due to increment excitations. The other method is to use self-diagnosis intelligent materials. According to the reinforced concrete beam specimen test, the second method can detect the damage by rupture of intelligent sensors, such as optical fiber or carbon fiber reinforced plastic rod.

Ubiquitination of HTLV-I Tax in response to DNA damage regulates nuclear complex formation and nuclear export

Directory of Open Access Journals (Sweden)

Marriott Susan J

2007-12-01

Full Text Available Abstract Background The HTLV-I oncoprotein, Tax, is a pleiotropic protein whose activity is partially regulated by its ability to interact with, and perturb the functions of, numerous cellular proteins. Tax is predominantly a nuclear protein that localizes to nuclear foci known as Tax Speckled Structures (TSS. We recently reported that the localization of Tax and its interactions with cellular proteins are altered in response to various forms of genotoxic and cellular stress. The level of cytoplasmic Tax increases in response to stress and this relocalization depends upon the interaction of Tax with CRM1. Cellular pathways and signals that regulate the subcellular localization of Tax remain to be determined. However, post-translational modifications including sumoylation and ubiquitination are known to influence the subcellular localization of Tax and its interactions with cellular proteins. The sumoylated form of Tax exists predominantly in the nucleus while ubiquitinated Tax exists predominantly in the cytoplasm. Therefore, we hypothesized that post-translational modifications of Tax that occur in response to DNA damage regulate the localization of Tax and its interactions with cellular proteins. Results We found a significant increase in mono-ubiquitination of Tax in response to UV irradiation. Mutation of specific lysine residues (K280 and K284 within Tax inhibited DNA damage-induced ubiquitination. In contrast to wild-type Tax, which undergoes transient nucleocytoplasmic shuttling in response to DNA damage, the K280 and K284 mutants were retained in nuclear foci following UV irradiation and remained co-localized with the cellular TSS protein, sc35. Conclusion This study demonstrates that the localization of Tax, and its interactions with cellular proteins, are dynamic following DNA damage and depend on the post-translational modification status of Tax. Specifically, DNA damage induces the ubiquitination of Tax at K280 and K284

Aerial pesticide application causes DNA damage in pilots from Sinaloa, Mexico.

Science.gov (United States)

Martínez-Valenzuela, C; Waliszewski, S M; Amador-Muñoz, O; Meza, E; Calderón-Segura, M E; Zenteno, E; Huichapan-Martínez, J; Caba, M; Félix-Gastélum, R; Longoria-Espinoza, R

2017-01-01

The use of pesticides in agricultural production originates residues in the environment where they are applied. Pesticide aerial application is a frequent source of exposure to pesticides by persons dedicated to agricultural practices and those living in neighboring communities of sprayed fields. The aim of the study was to assess the genotoxic effects of pesticides in workers occupationally exposed to these chemicals during their aerial application to agricultural fields of Sinaloa, Mexico. The study involved 30 pilots of airplanes used to apply pesticides via aerial application and 30 unexposed controls. Damage was evaluated through the micronucleus assay and by other nuclear abnormalities in epithelial cells of oral mucosa. The highest frequency ratios (FR) equal to 269.5 corresponded to binucleated cells followed by 54.2, corresponding to cells with pyknotic nuclei, 45.2 of cells with chromatin condensation, 3.7 of cells with broken-egg, 3.6 of cells with micronucleus, and 2.0 of karyolytic cells. Age, worked time, smoking, and alcohol consumption did not have significant influence on nuclear abnormalities in the pilots studied. Pesticide exposure was the main factor for nuclear abnormality results and DNA damage. Marked genotoxic damage was developed even in younger pilots with 2 years of short working period, caused by their daily occupational exposure to pesticides.

Determination of thymine glycol residues in irradiated or oxidized DNA by formation of methylglyceric acid

International Nuclear Information System (INIS)

Schellenberg, K.A.; Shaeffer, J.

1986-01-01

Treatment of DNA solutions with X-irradiation various oxidants including hydrogen peroxide plus ferrous ion, hydrogen peroxide plus copper ion and ascorbate, permanganate, or sonication in the presence of dissolved oxygen all produced varying amounts of thymine glycol residues. After denaturing the DNA with heat, the glycol residues were reduced and labeled at the 6 position with tritium- labeled sodium borohydride. Subsequent reaction with anhydrous methanolic HCl gave a quantitative yield of the methyl ester of methylglyceric acid, which was determined by thin layer chromatography. The method, developed using thymidine as a model, was used to ascertain the requirements for glycol formation in DNA. It was shown that hydroxyl radical generating systems, permanganate, X-irradiation, or sonication in presence of oxygen were required, but hydrogen peroxide in the absence of iron or copper and ascorbate was inactive. Application to determination of DNA damage in vivo is being explored

Post-processing of fused silica and its effects on damage resistance to nanosecond pulsed UV lasers.

Science.gov (United States)

Ye, Hui; Li, Yaguo; Zhang, Qinghua; Wang, Wei; Yuan, Zhigang; Wang, Jian; Xu, Qiao

2016-04-10

HF-based (hydrofluoric acid) chemical etching has been a widely accepted technique to improve the laser damage performance of fused silica optics and ensure high-power UV laser systems at designed fluence. Etching processes such as acid concentration, composition, material removal amount, and etching state (etching with additional acoustic power or not) may have a great impact on the laser-induced damage threshold (LIDT) of treated sample surfaces. In order to find out the effects of these factors, we utilized the Taguchi method to determine the etching conditions that are helpful in raising the LIDT. Our results show that the most influential factors are concentration of etchants and the material etched away from the viewpoint of damage performance of fused silica optics. In addition, the additional acoustic power (∼0.6  W·cm-2) may not benefit the etching rate and damage performance of fused silica. Moreover, the post-cleaning procedure of etched samples is also important in damage performances of fused silica optics. Different post-cleaning procedures were, thus, experiments on samples treated under the same etching conditions. It is found that the "spraying + rinsing + spraying" cleaning process is favorable to the removal of etching-induced deposits. Residuals on the etched surface are harmful to surface roughness and optical transmission as well as laser damage performance.

PENETAPAN RESIDU DAN PERKIRAAN PENETAPAN BATAS MAKSIMUM RESIDU (BMR ORGANOKLORIN PADA SIMPLISIA

Directory of Open Access Journals (Sweden)

Ani Isnawati

2012-10-01

Full Text Available Penggunaaan bahan obat tradisional (simplisia untuk skala industri dan peningkatan produksi tanaman obat dalam skala besar menjadi tidak ekonomis tanpa pestisida. Disatu sisi penggunaan pestisida dapat menguntungkan yaitu menyebabkan toksis pada hama namun disisi lain toksisitas dapat terjadi juga pada manusia, sehingga residu pestisida dalam tanaman obat yang dikonsumsi dalam jangka panjang akan merugikan kesehatan. Batas maksimum Residu (BMR pestisida dalam simplisia baik di Indonesia maupun di negara lain belum ditetapkan. Sehingga untuk itu untuk mengetahui adanya residu pestisida jenis organoklorin yang telah dilarang penggunaannya melalui Permentan No.434.1/kpts/TP.270/7/2001 dan untuk mengetahui batas keamanannya, maka perlu dilakukan penetapan residu organoklorin dalam simplisia dan menetapkan batas keamanan berdasarkan perhitungan secara teoritis. Pengujian residu dilakukan terhadap golongan pestisida organoklorin pada 4 jenis simplisia (daun wungu (Graptophyllum pictum (L Grifl, daun sambiloto Andrographis paniculata Ness, herba pegagan (Centella  asiatica (L Urban, daun tempuyung (Sonchus arvensis (L yang berasal dari 3 lokasi penanaman, yaitu : perkebunan Tanaman Obat Manako (Jawa Barat, Balai Penelitian Tanaman Obat Tawangmangu (BPTO di Jawa Tengah dan Perkebunan Tanaman Obat Purwodadi (Jawa Timur. Pemeriksaan residu pestisida organoklorin menggunakan kromatografi gas dan perhitungan batas keamanan dihitung dengan adanya nilai ADI (Acceptable daily intake yang telah ditetapkan bersama antara JAO dan WHO serta perkiraan banyaknya konsumsi simplisia. Hasil Pengujian residu pestisida organoklorin diperoleh bahwa simplisia daun Wungu (Tawangmangu mengandung residu lindan dengan kadar 0,24 mg/kg, pegagan (Purwodadi, mengandung lindan 0,36 mg/kg dan aldrin 0,31 mg/kg serta pegagan (Manako mengandung heptaklor 0,15 mg/kg dan op-DDE 0,11 mg/kg. Adapun penghitungan BMR heptaklor dan lindan secara teoritis dengan asumsi rata

The Effects of Foam Thermal Protection System on the Damage Tolerance Characteristics of Composite Sandwich Structures for Launch Vehicles

Science.gov (United States)

Nettles, A. T.; Hodge, A. J.; Jackson, J. R.

2011-01-01

For any structure composed of laminated composite materials, impact damage is one of the greatest risks and therefore most widely tested responses. Typically, impact damage testing and analysis assumes that a solid object comes into contact with the bare surface of the laminate (the outer ply). However, most launch vehicle structures will have a thermal protection system (TPS) covering the structure for the majority of its life. Thus, the impact response of the material with the TPS covering is the impact scenario of interest. In this study, laminates representative of the composite interstage structure for the Ares I launch vehicle were impact tested with and without the planned TPS covering, which consists of polyurethane foam. Response variables examined include maximum load of impact, damage size as detected by nondestructive evaluation techniques, and damage morphology and compression after impact strength. Results show that there is little difference between TPS covered and bare specimens, except the residual strength data is higher for TPS covered specimens.

Differentiation of Human Induced Pluripotent or Embryonic Stem Cells Decreases the DNA Damage Repair by Homologous Recombination

Directory of Open Access Journals (Sweden)

Kalpana Mujoo

2017-11-01

Full Text Available The nitric oxide (NO-cyclic GMP pathway contributes to human stem cell differentiation, but NO free radical production can also damage DNA, necessitating a robust DNA damage response (DDR to ensure cell survival. How the DDR is affected by differentiation is unclear. Differentiation of stem cells, either inducible pluripotent or embryonic derived, increased residual DNA damage as determined by γ-H2AX and 53BP1 foci, with increased S-phase-specific chromosomal aberration after exposure to DNA-damaging agents, suggesting reduced homologous recombination (HR repair as supported by the observation of decreased HR-related repair factor foci formation (RAD51 and BRCA1. Differentiated cells also had relatively increased fork stalling and R-loop formation after DNA replication stress. Treatment with NO donor (NOC-18, which causes stem cell differentiation has no effect on double-strand break (DSB repair by non-homologous end-joining but reduced DSB repair by HR. Present studies suggest that DNA repair by HR is impaired in differentiated cells.

Residual magnetic field in rotary machines; Campo magnetico residual en maquinas rotatorias

Energy Technology Data Exchange (ETDEWEB)

Gonzalez V, Esteban A; Apanco R, Marcelino [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico)

2007-07-01

The residual magnetism is a phenomenon in which the magnetic dipoles of a substance are oriented in a certain degree. On the other hand, when internal forces exist capable of aligning elementary magnetic dipoles of a material, a permanent magnet is obtained. Just as in a conductor or in a material, in the elements of a rotary electrical machine magnetic fields can be induced that produce a residual magnetism or magnetization. In the rotary electrical machines, the magnetization phenomenon causes serious problems, such as the generation of induced currents that propitiate the mechanical wear in bearings, collars, trunnions and inclusive in the shaft, by effects known as pitting, frosting and spark tracks, as well as erroneous readings in vibration and temperature sensors, that in some cases can cause the shut down of the machine. In this article are presented the general concepts on the residual magnetism in rotary electrical machines, the causes that originate it and the problems that arises, as well as the demagnetization of the components that have residual magnetic field. The results obtained by the area of Electrical Equipment of the Instituto de Investigaciones Electricas are revised, during the execution of activities related to the measurement and elimination of the residual magnetic field in rotary electrical machines. [Spanish] El magnetismo residual es un fenomeno en el que los dipolos magneticos de una sustancia se encuentran orientados en un grado determinado. Por otro lado, cuando existen fuerzas internas capaces de alinear los dipolos magneticos elementales de un material, se tiene un iman permanente. Al igual que en un conductor o un material, en los elementos de una maquina electrica rotatoria se pueden inducir campos magneticos que producen un magnetismo residual o magnetizacion. En las maquinas electricas rotatorias, el fenomeno de magnetizacion causa graves problemas, como la generacion de corrientes inducidas que propician el desgaste mecanico

Stress relaxation damage in K9 glass plate irradiated by 1.06μm CW laser

International Nuclear Information System (INIS)

Luo Fu; Sun Chengwei

2001-01-01

Based on the stress relaxation model in 1D planar geometry and the visco-elastic constitutive equation, the temperature and stress histories in the K9 glass samples irradiated by CW laser beams (λ = 1.06 μm) have been calculated. The results indicate that the residual tensile stress due to the stress relaxation effect during cooling after the laser radiation may be greater than the tensile fracture strength of samples, while the maximum compression stress during the laser heating is less than the requirement for compression damage. For a K9 glass window of 3 mm thickness, its damage due to the stress relaxation may be induced by a laser radiation of 0.946 MW/cm 2 for 0.2s . Therefore, the stress relaxation should be regarded as the main mechanism of damage in K9 glass windows while a CW laser beam (λ = 1.06 μm) irradiates it with large spot

submitter Damage evolution in a stainless steel bar undergoing phase transformation under torsion at cryogenic temperatures

CERN Document Server

Ortwein, R; Skoczen, B

2016-01-01

Phase transformation driven by plastic strains is commonly observed in austenitic stainless steels. In the present paper, this phenomenon is addressed in connection with damage evolution. A three-dimensional constitutive model has been derived, and scalar variables for damage and the volume fraction of the transformed phase were used. The model was solved using Abaqus UMAT user defined procedure, as well as by means of simplified one-dimensional approach for a twisted circular bar. Large experimental campaign of tests was performed, including martensite content measurements within the cross-section and on the surface of the bar during monotonic and cyclic loading. Based on the residual angle of twist, damage variable was calculated. The global response of torque versus the angle of twist was measured as well. Comparison between the experimental results and the results obtained from the simplified one-dimensional approach and from the full three-dimensional approach are presented. It turns out that one-dimensi...

The reaction {sup 48}Ca+{sup 248}Cm{yields}{sup 296}116{sup *} studied at the GSI-SHIP

Energy Technology Data Exchange (ETDEWEB)

Hofmann, S. [GSI Helmholtzzentrum fuer Schwerionenforschung, Darmstadt (Germany); Goethe-Universitaet Frankfurt, Institut fuer Physik, Frankfurt (Germany); Heinz, S.; Mann, R.; Khuyagbaatar, J.; Ackermann, D.; Barth, W.; Block, M.; Burkhard, H.G.; Comas, V.F.; Dahl, L.; Heredia, J.A.; Kindler, B.; Kojouharov, I.; Lang, R.; Lommel, B.; Muenzenberg, G.; Tinschert, K. [GSI Helmholtzzentrum fuer Schwerionenforschung, Darmstadt (Germany); Maurer, J.; Hessberger, F.P. [GSI Helmholtzzentrum fuer Schwerionenforschung, Darmstadt (Germany); Johannes Gutenberg-Universitaet, Helmholtz-Institut Mainz, Mainz (Germany); Antalic, S.; Saro, S. [Comenius University, Department of Nuclear Physics and Biophysics, Bratislava (Slovakia); Eberhardt, K.; Kratz, J.V.; Runke, J.; Thoerle-Pospiech, P.; Trautmann, N. [Johannes Gutenberg-Universitaet Mainz, Mainz (Germany); Gostic, J.; Henderson, R.A.; Kenneally, J.M.; Moody, K.J.; Nelson, S.L.; Shaughnessy, D.A.; Stoyer, M.A.; Wilk, P.A. [Lawrence Livermore National Laboratory, Livermore, CA (United States); Leino, M.; Uusitalo, J. [University of Jyvaeskylae, Department of Physics, Jyvaeskylae (Finland); Nishio, K. [Japan Atomic Energy Agency, Tokai, Ibaraki (Japan); Popeko, A.G.; Yeremin, A.V. [Joint Institute for Nuclear Research, Dubna (Russian Federation)

2012-05-15

The synthesis of element 116 in fusion-evaporation reactions of a {sup 48}Ca beam with radioactive {sup 248}Cm targets was studied at the velocity filter SHIP of GSI in Darmstadt. At excitation energies of the compound nuclei of 40.9MeV, four decay chains were measured, which were assigned to the isotope {sup 292}116, and one chain, which was assigned to {sup 293}116. Measured cross-sections of (3.4{sub -1.6}{sup +2.7})pb and (0.9{sub -0.7}{sup +2.1}), respectively, and decay data of the chains agree with data measured previously at the Flerov Laboratory of Nuclear Reactions in Dubna. As a new result, one {alpha}-decay chain was measured, which terminates after four {alpha} decays by spontaneous fission. The {alpha} energies of the second-to-fourth decay are considerably higher than those measured for the {alpha} decays of {sup 289}114, {sup 285}Cn, and {sup 281}Ds and the spontaneous fission half-life is significantly longer than that of {sup 277}Hs measured in previous experiments. A possible assignment is discussed in the frame of excited quasiparticle states of nuclei populated in the decay chain from {sup 293}116. Also other possible assignments were considered and are discussed. At an excitation energy of 45.0MeV no events were observed resulting in a one-event cross-section limit of 1.6 pb. The technical aspects related with the use of radioactive target material at SHIP are described in detail. The experience gained in this experiment will serve as a basis for future experiments aiming to study still heavier elements at the velocity filter SHIP. (orig.)

Mapping allostery through computational glycine scanning and correlation analysis of residue-residue contacts.

Science.gov (United States)

Johnson, Quentin R; Lindsay, Richard J; Nellas, Ricky B; Fernandez, Elias J; Shen, Tongye

2015-02-24

Understanding allosteric mechanisms is essential for the physical control of molecular switches and downstream cellular responses. However, it is difficult to decode essential allosteric motions in a high-throughput scheme. A general two-pronged approach to performing automatic data reduction of simulation trajectories is presented here. The first step involves coarse-graining and identifying the most dynamic residue-residue contacts. The second step is performing principal component analysis of these contacts and extracting the large-scale collective motions expressed via these residue-residue contacts. We demonstrated the method using a protein complex of nuclear receptors. Using atomistic modeling and simulation, we examined the protein complex and a set of 18 glycine point mutations of residues that constitute the binding pocket of the ligand effector. The important motions that are responsible for the allostery are reported. In contrast to conventional induced-fit and lock-and-key binding mechanisms, a novel "frustrated-fit" binding mechanism of RXR for allosteric control was revealed.

Spectroscopic analyses on sonocatalytic damage to bovine serum albumin (BSA) induced by ZnO/hydroxylapatite (ZnO/HA) composite under ultrasonic irradiation

Science.gov (United States)

Wang, Zhiqiu; Li, Ying; Wang, Jun; Zou, Mingming; Gao, Jingqun; Kong, Yumei; Li, Kai; Han, Guangxi

ZnO/hydroxylapatite (ZnO/HA) composite with HA molar content of 6.0% was prepared by the method of precipitation and heat-treated at 500 °C for 40 min and was characterized by powder X-ray diffraction (XRD). The sonocatalytic activities of ZnO/HA composite was carried out through the damage of bovine serum albumin (BSA) in aqueous solution. Furthermore, the effects of several factors on the damage of BSA molecules were evaluated by means of UV-vis and fluorescence spectra. Experimental results indicated that the damage degree of BSA aggravated with the increase of ultrasonic irradiation time, irradiation power and ZnO/HA addition amount, but weakened with the increase of solution acidity and ionic strength. In addition, the damage site to BSA was also studied by synchronous fluorescence technology and the damage site was mainly at tryptophan (Trp) residue. This paper provides a valuable reference for driving sonocatalytic method to treat tumor in clinic application.

Measurement of the Residual Sodium and Reaction Compounds on a Cleaned Cold Trap

International Nuclear Information System (INIS)

Kim, Byung Ho; Jeong, Ji Young; Kim, Jong Man; Choi, Byung Hae; Nam, Ho Yun Nam

2006-01-01

The purpose of a cleaning process is to remove the residual sodium adhering to the component walls once it has been properly drained. It is necessary to clean and decontaminate a component, especially the large components of the primary coolant system; such as the intermediate heat exchangers and the primary pump. Improper and inadequate cleaning has in a number of cases resulted in problems in the storage, handling, and reuse of components. Inadequate and incomplete removal of sodium results in residues which may contain metallic sodium and alkaline compounds such as sodium hydroxide, sodium oxide, sodium carbonate, and various types of alcoholates. Reinsertion of components containing these compounds into a high-temperature sodium system can result in either a intergranular penetration characteristic of a high-oxygen sodium or an accelerated corrosion due to oxygen. Cleaning methods are needed that will avoid a deleterious local overheating, material surface degradation or deposits, a chemical, physical, or mechanical damage, and external effects. It is important to determine the levels of residual sodium that can be accepted so that those deleterious effects will not negate the reuse of the component. The purpose of this paper is to measure the amount of the sodium and the reaction compounds remaining on a component after a cleaning and prepare acceptable criteria for the reuse of components which have been subjected to a sodium cleaning

Characterization Report on Sand, Slag, and Crucible Residues and on Fluoride Residues

International Nuclear Information System (INIS)

Murray, A.M.

1999-01-01

This paper reports on the chemical characterization of the sand, slag, and crucible (SS and C) residues and the fluoride residues that may be shipped from the Rocky Flats Environmental Technology Site (RFETS) to Savannah River Site (SRS)

Haertel's turbidity test and extraction of conifer needles by benzene as methods for the determination of smoke-induced damage

Energy Technology Data Exchange (ETDEWEB)

Materna, J; Hrncirova, L

1960-01-01

The applicability of the Haertel turbidity test to the assessment of smoke damage to conifers is based on the observation that needles from smoke damage to conifers is based on the observation that needles from smoke-damaged areas eliminate less wax than undamaged needles. Of the various organic solvent and extraction methods tested, best results were obtained by a half-hour extraction of the wax from the needle surface with cold benzene. The evaporation residue from this extraction method contained only traces of components from the inside of the needles; microscopic examination of the surface of the needles revealed that all wax was removed from the needle surface fissures. Comparison of wax quantities extracted from needles from smoke-damage areas with those from healthy needles and comparison of wax yields from areas which suffered different degrees of smoke damage confirmed that higher wax yields are obtained from healthy than from smoke-damaged needles. Comparison with results of turbidity tests disclosed that benzene extraction yields decreased with increasing turbidity test values, indicating that increased turbidity of smoke-damaged needles is not caused by wax. In the Haertel test extract, silicon, calcium, magnesium, phosphorus, potassium, sulfur, iron, nitrogenous substances, tannin, glycides, and waxes were found. It is as yet unresolved which substances contribute to increased turbidity from smoke damage.

Carbon-carbon composite and copper-composite bond damages for high flux component controlled fusion

International Nuclear Information System (INIS)

Chevet, G.

2010-01-01

Plasma facing components constitute the first wall in contact with plasma in fusion machines such as Tore Supra and ITER. These components have to sustain high heat flux and consequently elevated temperatures. They are made up of an armour material, the carbon-carbon composite, a heat sink structure material, the copper chromium zirconium, and a material, the OFHC copper, which is used as a compliant layer between the carbon-carbon composite and the copper chromium zirconium. Using different materials leads to the apparition of strong residual stresses during manufacturing, because of the thermal expansion mismatch between the materials, and compromises the lasting operation of fusion machines as damage which appeared during manufacturing may propagate. The objective of this study is to understand the damage mechanisms of the carbon-carbon composite and the composite-copper bond under solicitations that plasma facing components may suffer during their life. The mechanical behaviours of carbon-carbon composite and composite-copper bond were studied in order to define the most suitable models to describe these behaviours. With these models, thermomechanical calculations were performed on plasma facing components with the finite element code Cast3M. The manufacturing of the components induces high stresses which damage the carbon-carbon composite and the composite-copper bond. The damage propagates during the cooling down to room temperature and not under heat flux. Alternative geometries for the plasma facing components were studied to reduce damage. The relation between the damage of the carbon-carbon composite and its thermal conductivity was also demonstrated. (author) [fr

Modeling event building architecture for the triggerless data acquisition system for PANDA experiment at the HESR facility at FAIR/GSI

International Nuclear Information System (INIS)

Korcyl, K; Konorov, I; Kühn, W; Schmitt, L

2012-01-01

A novel architecture is being proposed for the data acquisition and trigger system of the PANDA experiment at the HESR facility at FAIR/GSI. The experiment will run without hardware trigger signal using timestamps to correlate detector data from a given time window. The broad physics program in combination with the high rate of 2 * 10 7 interactions per second requires very selective filtering algorithms accessing information from many detectors. Therefore the effective filtering will happen later than in today's systems ie. after the event building. To assess that, the complete architecture will be built of two stages: the data concentrator stage providing event building and the rate reduction stage. For the former stage, which requires a throughput of 100 GB/s to perform event building, we propose two layers of ATCA crates filled with Compute Nodes - modules designed at IHEP and University of Giessen for trigger and data acquisition systems. Currently each board is equipped with 5 Virtex4 FX60 FPGAs and high bandwidth connectivity is provided by 8 front panel RocketIO ports and 12 backplane ports for the inter-module communication. We designed simplified models of the components of the architecture and using the SystemC library as support for the discrete event simulations, demonstrate the expected throughput of the full-size system. We also show impact of some architectural choices and key parameters on the architecture's performance.

FAA/NASA International Symposium on Advanced Structural Integrity Methods for Airframe Durability and Damage Tolerance

Energy Technology Data Exchange (ETDEWEB)

Harris, C.E.

1994-09-01

International technical experts in durability and damage tolerance of metallic airframe structures were assembled to present and discuss recent research findings and the development of advanced design and analysis methods, structural concepts, and advanced materials. The symposium focused on the dissemination of new knowledge and the peer-review of progress on the development of advanced methodologies. Papers were presented on: structural concepts for enhanced durability, damage tolerance, and maintainability; new metallic alloys and processing technology; fatigue crack initiation and small crack effects; fatigue crack growth models; fracture mechanics failure, criteria for ductile materials; structural mechanics methodology for residual strength and life prediction; development of flight load spectra for design and testing; and advanced approaches to resist corrosion and environmentally assisted fatigue. Separate abstracts have been indexed for articles from this report.

Residual stress by repair welds

International Nuclear Information System (INIS)

Mochizuki, Masahito; Toyoda, Masao

2003-01-01

Residual stress by repair welds is computed using the thermal elastic-plastic analysis with phase-transformation effect. Coupling phenomena of temperature, microstructure, and stress-strain fields are simulated in the finite-element analysis. Weld bond of a plate butt-welded joint is gouged and then deposited by weld metal in repair process. Heat source is synchronously moved with the deposition of the finite-element as the weld deposition. Microstructure is considered by using CCT diagram and the transformation behavior in the repair weld is also simulated. The effects of initial stress, heat input, and weld length on residual stress distribution are studied from the organic results of numerical analysis. Initial residual stress before repair weld has no influence on the residual stress after repair treatment near weld metal, because the initial stress near weld metal releases due to high temperature of repair weld and then stress by repair weld regenerates. Heat input has an effect for residual stress distribution, for not its magnitude but distribution zone. Weld length should be considered reducing the magnitude of residual stress in the edge of weld bead; short bead induces high tensile residual stress. (author)

The influence of lay-up and thickness on composite impact damage and compression strength

Science.gov (United States)

Guynn, E. G.; Obrien, T. K.

1985-01-01

The effects of composite stacking sequence, thickness, and percentage of zero-degree plies on the size, shape, and distribution of delamination through the laminate thickness and on residual compression strength following impact were studied. Graphite/epoxy laminates were impacted with an 0.5 inch diameter aluminum sphere at a specific low or high velocity. Impact damage was measured nondestructively by ultrasonic C-scans and X-radiography and destructively by the deply technique, and compression strength tests were performed. It was found that differences in compression failure strain due to stacking sequence were small, while laminates with very low percentages of zero-degree plies had similar failure loads but higher failure strains than laminates with higher percentages of zero-degree plies. Failure strain did not correlate with planar impact damage area, and delaminations in impact regions were associated with matrix cracking.

Mechanical Characterization of Thermomechanical Matrix Residual Stresses Incurred During MMC Processing

Science.gov (United States)

Castelli, Michael G.

1998-01-01

In recent years, much effort has been spent examining the residual stress-strain states of advanced composites. Such examinations are motivated by a number of significant concerns that affect composite development, processing, and analysis. The room-temperature residual stress states incurred in many advanced composite systems are often quite large and can introduce damage even prior to the first external mechanical loading of the material. These stresses, which are induced during the cooldown following high-temperature consolidation, result from the coefficient of thermal expansion mismatch between the fiber and matrix. Experimental techniques commonly used to evaluate composite internal residual stress states are non-mechanical in nature and generally include forms of x-ray and neutron diffraction. Such approaches are usually complex, involving a number of assumptions and limitations associated with a wide range of issues, including the depth of penetration, the volume of material being assessed, and erroneous effects associated with oriented grains. Furthermore, and more important to the present research, these techniques can assess only "single time" stress in the composite. That is, little, if any, information is obtained that addresses the time-dependent point at which internal stresses begin to accumulate, the manner in which the accumulation occurs, and the presiding relationships between thermoelastic, thermoplastic, and thermoviscous behaviors. To address these critical issues, researchers at the NASA Lewis Research Center developed and implemented an innovative mechanical test technique to examine in real time, the time-dependent thermomechanical stress behavior of a matrix alloy as it went through a consolidation cycle.

Reactivity of Athabasca residue and of its SARA fractions during residue hydroconversion

Energy Technology Data Exchange (ETDEWEB)

Verstraete, J.; Danial-Fortain, P.; Gauthier, T.; Merdrignac, I. [IFP-Lyon, Vermaison (France); Budzinski, H. [Bordeaux Univ. (France). ISM-LPTC, UMR CNRS

2009-07-01

Residue conversion processes are becoming increasingly important because of the declining market for residual fuel oil and a greater demand for middle distillates. Ebullated-bed hydroconversion is a commercially proven technology for converting heavy feedstocks with high amounts of impurities. The process enables the conversion of atmospheric or vacuum residues at temperatures up to 440 degrees C, and at liquid hourly space velocity (LHSV) conditions in the range of 0.15 to 0.5 per hour. A 540 degrees C conversion of up to 80 weight per cent can be achieved under these conditions. This paper reported on a research study conducted at IFP Lyon in which the residue hydroconversion in a large-scale ebullated bed bench unit was investigated to determine the impact of operating conditions and feed properties on yield and product qualities. Hydrogen was added to the feed in the bench units to keep a high hydrogen partial pressure and favour the catalytic hydroconversion reactions. In a typical test, the reactor was fed with 50 g of feedstock and 0.45 g of crushed equilibrium industrial NiMo catalyst, pressurized hydrogen and quickly heated at the reaction temperature. This paper also discussed the conversion of Athabasca bitumen residue in the large-scale pilot plant and also in the small scale batch reactor. The effect of operating temperature and space velocity was examined. The reactivity of the saturates, aromatics, resins and asphaltenes (SARA) fractions of the bitumen was studied separately in order to better understand the conversion mechanisms and reactivities. The Athabasca bitumen feed and SARA fractions were also analyzed in terms of standard petroleum analysis, SARA fractionation, elemental analysis, size exclusion chromatography (SEC) and 13C NMR. Hydroconversion experiments were conducted in the batch unit at different reaction temperatures and reaction times. A comparison of small-scale batch results with those obtained with the continuous large-scale bench

Hide and seek: How do DNA glycosylases locate oxidatively damaged DNA bases amidst a sea of undamaged bases?

Science.gov (United States)

Lee, Andrea J; Wallace, Susan S

2017-06-01

The first step of the base excision repair (BER) pathway responsible for removing oxidative DNA damage utilizes DNA glycosylases to find and remove the damaged DNA base. How glycosylases find the damaged base amidst a sea of undamaged bases has long been a question in the BER field. Single molecule total internal reflection fluorescence microscopy (SM TIRFM) experiments have allowed for an exciting look into this search mechanism and have found that DNA glycosylases scan along the DNA backbone in a bidirectional and random fashion. By comparing the search behavior of bacterial glycosylases from different structural families and with varying substrate specificities, it was found that glycosylases search for damage by periodically inserting a wedge residue into the DNA stack as they redundantly search tracks of DNA that are 450-600bp in length. These studies open up a wealth of possibilities for further study in real time of the interactions of DNA glycosylases and other BER enzymes with various DNA substrates. Copyright © 2016 Elsevier Inc. All rights reserved.

Elemental Concentrations in Urban Green Stormwater Infrastructure Soils.

Science.gov (United States)

Kondo, Michelle C; Sharma, Raghav; Plante, Alain F; Yang, Yunwen; Burstyn, Igor

2016-01-01

Green stormwater infrastructure (GSI) is designed to capture stormwater for infiltration, detention, evapotranspiration, or reuse. Soils play a key role in stormwater interception at these facilities. It is important to assess whether contamination is occurring in GSI soils because urban stormwater drainage areas often accumulate elements of concern. Soil contamination could affect hydrologic and ecosystem functions. Maintenance workers and the public may also be exposed to GSI soils. We investigated soil elemental concentrations, categorized as macro- and micronutrients, heavy metals, and other elements, at 59 GSI sites in the city of Philadelphia. Non-GSI soil samples 3 to 5 m upland of GSI sites were used for comparison. We evaluated differences in elemental composition in GSI and non-GSI soils; the comparisons were corrected for the age of GSI facility, underlying soil type, street drainage, and surrounding land use. Concentrations of Ca and I were greater than background levels at GSI sites. Although GSI facilities appear to accumulate Ca and I, these elements do not pose a significant human health risk. Elements of concern to human health, including Cd, Hg, and Pb, were either no different or were lower in GSI soils compared with non-GSI soils. However, mean values found across GSI sites were up to four times greater than soil cleanup objectives for residential use. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

Estimate of radiation damage to low-level electronics of the RF system in the LHC cavities arising from beam gas collisions

International Nuclear Information System (INIS)

Butterworth, A.; Ferrari, A.; Tsoulou, E.; Vlachoudis, V.; Wijnands, T.

2005-01-01

Monte Carlo simulations have been performed to estimate the radiation damage induced by high-energy hadrons in the digital electronics of the RF low-level systems in the LHC cavities. High-energy hadrons are generated when the proton beams interact with the residual gas. The contributions from various elements - vacuum chambers, cryogenic cavities, wideband pickups and cryo-module beam tubes - have been considered individually, with each contribution depending on the gas composition and density. The probability of displacement damage and single event effects (mainly single event upsets) is derived for the LHC start-up conditions. (authors)

Evaluating the damage of steel 09G2S under static and cyclic loading with regard for the level of residual stresses in the metal

Science.gov (United States)

Kuznetsov, A. V.; Kamantsev, I. S.; Zadvorkin, S. M.; Drukarenko, N. A.; Goruleva, L. S.; Veselova, V. E.

2017-12-01

An approach to the estimation of the residual durability of structural elements in view of their initial stress-strain state is proposed. The adequacy of the developed approach is confirmed by experiments on cyclic loading of specimens without pronounced stress concentrators simulating the work of real structural elements under conditions of overshooting the total stresses causing local plastic deformation of the material, with regard for residual stresses.

Automated Damage Onset Analysis Techniques Applied to KDP Damage and the Zeus Small Area Damage Test Facility

International Nuclear Information System (INIS)

Sharp, R.; Runkel, M.

1999-01-01

Automated damage testing of KDP using LLNL's Zeus automated damage test system has allowed the statistics of KDP bulk damage to be investigated. Samples are now characterized by the cumulative damage probability curve, or S-curve, that is generated from hundreds of individual test sites per sample. A HeNe laser/PMT scatter diagnostic is used to determine the onset of damage at each test site. The nature of KDP bulk damage is such that each scatter signal may possess many different indicators of a damage event. Because of this, the determination of the initial onset for each scatter trace is not a straightforward affair and has required considerable manual analysis. The amount of testing required by crystal development for the National Ignition Facility (NIF) has made it impractical to continue analysis by hand. Because of this, we have developed and implemented algorithms for analyzing the scatter traces by computer. We discuss the signal cleaning algorithms and damage determination criteria that have lead to the successful implementation of a LabView based analysis code. For the typical R/1 damage data set, the program can find the correct damage onset in more than 80% of the cases, with the remaining 20% being left to operator determination. The potential time savings for data analysis is on the order of ∼ 100X over manual analysis and is expected to result in the savings of at least 400 man-hours over the next 3 years of NIF quality assurance testing

Assessing the physical vulnerability of check dams through an empirical damage index

Directory of Open Access Journals (Sweden)

Andrea Dell'Agnese

2013-06-01

Full Text Available A comprehensive analysis of flood risk in mountain streams has to include an assessment of the vulnerability of the protection systems, in addition to an assessment of the vulnerability of the constructed environment on alluvial fans and floodplains. Structures forming the protection systems are of a dual nature, i.e. they are designed to mitigate natural process-related hazards and, on the other hand, are prone to be damaged during their lifecycle by the same processes they should mitigate. Therefore, their effectiveness declines over time. Hence, the knowledge of how effectively control structures perform is essential for risk management. A procedure was developed to assess the physical vulnerability of check dams based on empirical evidence collected in South Tyrol, Northern Italy. A damage index defined on pre- and postevent comparisons of check dam conditions was evaluated for 362 structures in 18 mountain streams along with the relevant processes and the structural characteristics affecting it. Although the available dataset did not allow conclusive functional relationships between damage index and impact variables to be established, it was possible to assess the average expected residual functionality of check dams according to structure characteristics, and event type and intensity. These results may help plan appropriate check dam maintenance.

Effects of Common Fig (Ficus carica Leaf Extracts on Sperm Parameters and Testis of Mice Intoxicated with Formaldehyde

Directory of Open Access Journals (Sweden)

Majid Naghdi

2016-01-01

Full Text Available Formaldehyde (FA is the leading cause of cellular injury and oxidative damage in testis that is one of the main infertility causes. There has been an increasing evidence of herbal remedies use in male infertility treatment. This assay examines the role of Ficus carica (Fc leaf extracts in sperm parameters and testis of mice intoxicated with FA. Twenty-five adult male mice were randomly divided into control; sham; FA-treated (10 mg/kg twice per day; Fc-treated (200 mg/kg; and FA + Fc-treated groups. Cauda epididymal spermatozoa were analyzed for viability, count, and motility. Testes were weighed and gonadosomatic index (GSI was calculated. Also, histoarchitecture of seminiferous tubules was assessed in the Haematoxylin and Eosin stained paraffin sections. The findings showed that FA significantly decreased GSI and increased percentage of immotile sperm compared with control group. Disorganized and vacuolated seminiferous epithelium, spermatogenic arrest, and lumen filled with immature germ cells were also observed in the testes. However, Fc leaf extracts improved sperm count, nonprogressive motility of spermatozoa, and GSI in FA-treated testes. Moreover, seminiferous tubule with spermatogenic arrest was rarely seen, indicating that Fc has the positive effects on testis and epididymal sperm parameters exposed with FA.

Identification of residue pairing in interacting β-strands from a predicted residue contact map.

Science.gov (United States)

Mao, Wenzhi; Wang, Tong; Zhang, Wenxuan; Gong, Haipeng

2018-04-19

Despite the rapid progress of protein residue contact prediction, predicted residue contact maps frequently contain many errors. However, information of residue pairing in β strands could be extracted from a noisy contact map, due to the presence of characteristic contact patterns in β-β interactions. This information may benefit the tertiary structure prediction of mainly β proteins. In this work, we propose a novel ridge-detection-based β-β contact predictor to identify residue pairing in β strands from any predicted residue contact map. Our algorithm RDb 2 C adopts ridge detection, a well-developed technique in computer image processing, to capture consecutive residue contacts, and then utilizes a novel multi-stage random forest framework to integrate the ridge information and additional features for prediction. Starting from the predicted contact map of CCMpred, RDb 2 C remarkably outperforms all state-of-the-art methods on two conventional test sets of β proteins (BetaSheet916 and BetaSheet1452), and achieves F1-scores of ~ 62% and ~ 76% at the residue level and strand level, respectively. Taking the prediction of the more advanced RaptorX-Contact as input, RDb 2 C achieves impressively higher performance, with F1-scores reaching ~ 76% and ~ 86% at the residue level and strand level, respectively. In a test of structural modeling using the top 1 L predicted contacts as constraints, for 61 mainly β proteins, the average TM-score achieves 0.442 when using the raw RaptorX-Contact prediction, but increases to 0.506 when using the improved prediction by RDb 2 C. Our method can significantly improve the prediction of β-β contacts from any predicted residue contact maps. Prediction results of our algorithm could be directly applied to effectively facilitate the practical structure prediction of mainly β proteins. All source data and codes are available at http://166.111.152.91/Downloads.html or the GitHub address of https://github.com/wzmao/RDb2C .

Residuals and the Residual-Based Statistic for Testing Goodness of Fit of Structural Equation Models

Science.gov (United States)

Foldnes, Njal; Foss, Tron; Olsson, Ulf Henning

2012-01-01

The residuals obtained from fitting a structural equation model are crucial ingredients in obtaining chi-square goodness-of-fit statistics for the model. The authors present a didactic discussion of the residuals, obtaining a geometrical interpretation by recognizing the residuals as the result of oblique projections. This sheds light on the…

Nitroxides are more efficient inhibitors of oxidative damage to calf skin collagen than antioxidant vitamins.

Science.gov (United States)

Venditti, Elisabetta; Scirè, Andrea; Tanfani, Fabio; Greci, Lucedio; Damiani, Elisabetta

2008-01-01

Reactive oxygen species generated upon UV-A exposure appear to play a major role in dermal connective tissue transformations including degradation of skin collagen. Here we investigate on oxidative damage to collagen achieved by exposure to (i) UV-A irradiation and to (ii) AAPH-derived radicals and on its possible prevention using synthetic and natural antioxidants. Oxidative damage was identified through SDS-PAGE, circular dichroism spectroscopy and quantification of protein carbonyl residues. Collagen (2 mg/ml) exposed to UV-A and to AAPH-derived radicals was degraded in a time- and dose-dependent manner. Upon UV-A exposure, maximum damage was observable at 730 kJ/m2 UV-A, found to be equivalent to roughly 2 h of sunshine, while exposure to 5 mM AAPH for 2 h at 50 degrees C lead to maximum collagen degradation. In both cases, dose-dependent protection was achieved by incubation with muM concentrations of nitroxide radicals, where the extent of protection was shown to be dictated by their structural differences whereas the vitamins E and C proved less efficient inhibitors of collagen damage. These results suggest that nitroxide radicals may be able to prevent oxidative injury to dermal tissues in vivo alternatively to commonly used natural antioxidants.

Compressive Residual Strains in Mineral Nanoparticles as a Possible Origin of Enhanced Crack Resistance in Human Tooth Dentin.

Science.gov (United States)

Forien, Jean-Baptiste; Fleck, Claudia; Cloetens, Peter; Duda, Georg; Fratzl, Peter; Zolotoyabko, Emil; Zaslansky, Paul

2015-06-10

The tough bulk of dentin in teeth supports enamel, creating cutting and grinding biostructures with superior failure resistance that is not fully understood. Synchrotron-based diffraction methods, utilizing micro- and nanofocused X-ray beams, reveal that the nm-sized mineral particles aligned with collagen are precompressed and that the residual strains vanish upon mild annealing. We show the link between the mineral nanoparticles and known damage propagation trajectories in dentin, suggesting a previously overlooked compression-mediated toughening mechanism.

Evaluation of nuclear power plant component failure probability and core damage probability using simplified PSA model

International Nuclear Information System (INIS)

Shimada, Yoshio

2000-01-01

It is anticipated that the change of frequency of surveillance tests, preventive maintenance or parts replacement of safety related components may cause the change of component failure probability and result in the change of core damage probability. It is also anticipated that the change is different depending on the initiating event frequency or the component types. This study assessed the change of core damage probability using simplified PSA model capable of calculating core damage probability in a short time period, which is developed by the US NRC to process accident sequence precursors, when various component's failure probability is changed between 0 and 1, or Japanese or American initiating event frequency data are used. As a result of the analysis, (1) It was clarified that frequency of surveillance test, preventive maintenance or parts replacement of motor driven pumps (high pressure injection pumps, residual heat removal pumps, auxiliary feedwater pumps) should be carefully changed, since the core damage probability's change is large, when the base failure probability changes toward increasing direction. (2) Core damage probability change is insensitive to surveillance test frequency change, since the core damage probability change is small, when motor operated valves and turbine driven auxiliary feed water pump failure probability changes around one figure. (3) Core damage probability change is small, when Japanese failure probability data are applied to emergency diesel generator, even if failure probability changes one figure from the base value. On the other hand, when American failure probability data is applied, core damage probability increase is large, even if failure probability changes toward increasing direction. Therefore, when Japanese failure probability data is applied, core damage probability change is insensitive to surveillance tests frequency change etc. (author)

FAA/NASA International Symposium on Advanced Structural Integrity Methods for Airframe Durability and Damage Tolerance, part 2

Science.gov (United States)

Harris, Charles E. (Editor)

1994-01-01

The international technical experts in the areas of durability and damage tolerance of metallic airframe structures were assembled to present and discuss recent research findings and the development of advanced design and analysis methods, structural concepts, and advanced materials. The principal focus of the symposium was on the dissemination of new knowledge and the peer-review of progress on the development of advanced methodologies. Papers were presented on the following topics: structural concepts for enhanced durability, damage tolerance, and maintainability; new metallic alloys and processing technology; fatigue crack initiation and small crack effects; fatigue crack growth models; fracture mechanics failure criteria for ductile materials; structural mechanics methodology for residual strength and life prediction; development of flight load spectra for design and testing; and corrosion resistance.

Residual γH2AX foci as an indication of lethal DNA lesions

Directory of Open Access Journals (Sweden)

Banuelos C Adriana

2010-01-01

Full Text Available Abstract Background Evidence suggests that tumor cells exposed to some DNA damaging agents are more likely to die if they retain microscopically visible γH2AX foci that are known to mark sites of double-strand breaks. This appears to be true even after exposure to the alkylating agent MNNG that does not cause direct double-strand breaks but does produce γH2AX foci when damaged DNA undergoes replication. Methods To examine this predictive ability further, SiHa human cervical carcinoma cells were exposed to 8 DNA damaging drugs (camptothecin, cisplatin, doxorubicin, etoposide, hydrogen peroxide, MNNG, temozolomide, and tirapazamine and the fraction of cells that retained γH2AX foci 24 hours after a 30 or 60 min treatment was compared with the fraction of cells that lost clonogenicity. To determine if cells with residual repair foci are the cells that die, SiHa cervical cancer cells were stably transfected with a RAD51-GFP construct and live cell analysis was used to follow the fate of irradiated cells with RAD51-GFP foci. Results For all drugs regardless of their mechanism of interaction with DNA, close to a 1:1 correlation was observed between clonogenic surviving fraction and the fraction of cells that retained γH2AX foci 24 hours after treatment. Initial studies established that the fraction of cells that retained RAD51 foci after irradiation was similar to the fraction of cells that retained γH2AX foci and subsequently lost clonogenicity. Tracking individual irradiated live cells confirmed that SiHa cells with RAD51-GFP foci 24 hours after irradiation were more likely to die. Conclusion Retention of DNA damage-induced γH2AX foci appears to be indicative of lethal DNA damage so that it may be possible to predict tumor cell killing by a wide variety of DNA damaging agents simply by scoring the fraction of cells that retain γH2AX foci.

Residual γH2AX foci as an indication of lethal DNA lesions

International Nuclear Information System (INIS)

Banáth, Judit P; Klokov, Dmitry; MacPhail, Susan H; Banuelos, C Adriana; Olive, Peggy L

2010-01-01

Evidence suggests that tumor cells exposed to some DNA damaging agents are more likely to die if they retain microscopically visible γH2AX foci that are known to mark sites of double-strand breaks. This appears to be true even after exposure to the alkylating agent MNNG that does not cause direct double-strand breaks but does produce γH2AX foci when damaged DNA undergoes replication. To examine this predictive ability further, SiHa human cervical carcinoma cells were exposed to 8 DNA damaging drugs (camptothecin, cisplatin, doxorubicin, etoposide, hydrogen peroxide, MNNG, temozolomide, and tirapazamine) and the fraction of cells that retained γH2AX foci 24 hours after a 30 or 60 min treatment was compared with the fraction of cells that lost clonogenicity. To determine if cells with residual repair foci are the cells that die, SiHa cervical cancer cells were stably transfected with a RAD51-GFP construct and live cell analysis was used to follow the fate of irradiated cells with RAD51-GFP foci. For all drugs regardless of their mechanism of interaction with DNA, close to a 1:1 correlation was observed between clonogenic surviving fraction and the fraction of cells that retained γH2AX foci 24 hours after treatment. Initial studies established that the fraction of cells that retained RAD51 foci after irradiation was similar to the fraction of cells that retained γH2AX foci and subsequently lost clonogenicity. Tracking individual irradiated live cells confirmed that SiHa cells with RAD51-GFP foci 24 hours after irradiation were more likely to die. Retention of DNA damage-induced γH2AX foci appears to be indicative of lethal DNA damage so that it may be possible to predict tumor cell killing by a wide variety of DNA damaging agents simply by scoring the fraction of cells that retain γH2AX foci

Machine for compacting solid residues

International Nuclear Information System (INIS)

Herzog, J.

1981-11-01

Machine for compacting solid residues, particularly bulky radioactive residues, constituted of a horizontally actuated punch and a fixed compression anvil, in which the residues are first compacted horizontally and then vertically. Its salient characteristic is that the punch and the compression anvil have embossments on the compression side and interpenetrating plates in the compression position [fr

A Monte-Carlo code for neutron efficiency calculations for large volume Gd-loaded liquid scintillation detectors

Energy Technology Data Exchange (ETDEWEB)

Trzcinski, A.; Zwieglinski, B. [Soltan Inst. for Nuclear Studies, Warsaw (Poland); Lynen, U. [Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany); Pochodzalla, J. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany)

1998-10-01

This paper reports on a Monte-Carlo program, MSX, developed to evaluate the performance of large-volume, Gd-loaded liquid scintillation detectors used in neutron multiplicity measurements. The results of simulations are presented for the detector intended to count neutrons emitted by the excited target residue in coincidence with the charged products of the projectile fragmentation following relativistic heavy-ion collisions. The latter products could be detected with the ALADIN magnetic spectrometer at GSI-Darmstadt. (orig.) 61 refs.

Early recognition of damage and course of damage on metal components

International Nuclear Information System (INIS)

1992-01-01

In 1985, the German Research Association set up the programme 'Early recognition of damage and course of damage on metal components'. The concept worked out by a programme committee provided that scientifically secured bases for the understanding of the occurrence of damage, the prevention of damage, affecting damage, and the mechanism triggering damage, or cumulation of damage should be obtained. 36 individual projects costing 14 million DM were supported in the course of 6 years. The task of a test group was to find these projects from a far larger number of applications which promised an increase in knowledge in the sense of the target of the programme. For the final colloquium, the test group chose those contributions which had not previously been published to the wider technical public. (orig.) [de

Residual stress concerns in containment analysis

International Nuclear Information System (INIS)

Costantini, F.; Kulak, R. F.; Pfeiffer, P. A.

1997-01-01

The manufacturing of steel containment vessels starts with the forming of flat plates into curved plates. A steel containment structure is made by welding individual plates together to form the sections that make up the complex shaped vessels. The metal forming and welding process leaves residual stresses in the vessel walls. Generally, the effect of metal forming residual stresses can be reduced or virtually eliminated by thermally stress relieving the vesseL In large containment vessels this may not be practical and thus the residual stresses due to manufacturing may become important. The residual stresses could possibly tiect the response of the vessel to internal pressurization. When the level of residual stresses is significant it will affect the vessel's response, for instance the yielding pressure and possibly the failure pressure. The paper will address the effect of metal forming residual stresses on the response of a generic pressure vessel to internal pressurization. A scoping analysis investigated the effect of residual forming stresses on the response of an internally pressurized vessel. A simple model was developed to gain understanding of the mechanics of the problem. Residual stresses due to the welding process were not considered in this investigation

Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.

Science.gov (United States)

Zhou, Yi; Lee, Ji-Hoon; Jiang, Wenxia; Crowe, Jennie L; Zha, Shan; Paull, Tanya T

2017-01-05

Ataxia-telangiectasia mutated (ATM) regulates the DNA damage response as well as DNA double-strand break repair through homologous recombination. Here we show that ATM is hyperactive when the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) is chemically inhibited or when the DNA-PKcs gene is deleted in human cells. Pre-incubation of ATM protein with active DNA-PKcs also significantly reduces ATM activity in vitro. We characterize several phosphorylation sites in ATM that are targets of DNA-PKcs and show that phospho-mimetic mutations at these residues significantly inhibit ATM activity and impair ATM signaling upon DNA damage. In contrast, phospho-blocking mutations at one cluster of sites increase the frequency of apoptosis during normal cell growth. DNA-PKcs, which is integral to the non-homologous end joining pathway, thus negatively regulates ATM activity through phosphorylation of ATM. These observations illuminate an important regulatory mechanism for ATM that also controls DNA repair pathway choice. Copyright © 2017 Elsevier Inc. All rights reserved.

Determination of temperature and residual laser energy on film fiber-optic thermal converter for diode laser surgery.

Science.gov (United States)

Liu, Weichao; Kong, Yaqun; Shi, Xiafei; Dong, Xiaoxi; Wang, Hong; Zhao, Jizhi; Li, Yingxin

2017-12-01

The diode laser was utilized in soft tissue incision of oral surgery based on the photothermic effect. The contradiction between the ablation efficiency and the thermal damage has always been in diode laser surgery, due to low absorption of its radiation in the near infrared region by biological tissues. Fiber-optic thermal converters (FOTCs) were used to improve efficiency for diode laser surgery. The purpose of this study was to determine the photothermic effect by the temperature and residual laser energy on film FOTCs. The film FOTC was made by a distal end of optical fiber impacting on paper. The external surface of the converter is covered by a film contained amorphous carbon. The diode laser with 810 nm worked at the different rated power of 1.0 W, 1.5 W, 2.0 W, 3.0 W, 4.0 W, 5.0 W, 6.0 W, 7.0 W, 8.0 W in continuous wave (CW)and pulse mode. The temperature of the distal end of optical fiber was recorded and the power of the residual laser energy from the film FOTC was measured synchronously. The temperature, residual power and the output power were analyzed by linear or exponential regression model and Pearson correlations analysis. The residual power has good linearity versus output power in CW and pulse modes (R 2  = 0.963, P film FOTCs increases exponentially with adjusted R 2  = 0.959 in continuous wave mode, while in pulsed mode with adjusted R 2  = 0.934. The temperature was elevated up to about 210 °C and eventually to be a stable state. Film FOTCs centralized approximately 50% of laser energy on the fiber tip both in CW and pulsed mode while limiting the ability of the laser light to interact directly with target tissue. Film FOTCs can concentrate part of laser energy transferred to heat on distal end of optical fiber, which have the feasibility of improving efficiency and reducing thermal damage of deep tissue.

Diode characteristics and residual deep-level defects of p+n abrupt junctions fabricated by rapid thermal annealing of boron implanted silicon

International Nuclear Information System (INIS)

Usami, A.; Katayama, M.; Wada, T.; Tokuda, Y.

1987-01-01

p + n diodes were fabricated by rapid thermal annealing (RTA) of boron implanted silicon in the annealing temperature range 700-1100 0 C for around 7 s, and the RTA temperature dependence of electrical characteristics of these diodes was studied. Deep-level transient spectroscopy (DLTS) measurements were made to evaluate residual deep-level defects in the n-type bulk. Three electron traps were observed in p + n diodes fabricated by RTA at 700 0 C. It was considered that these three traps were residual point defects near the tail of the implantation damage after RTA. Residual defect concentrations increased in the range 700-900 0 C and decreased in the range 1000-1100 0 C. The growth of defects in the bulk was ascribed to the diffusion of defects from the implanted layer during RTA. Concentrations of electron traps observed in p + n diodes fabricated by RTA at 1100 0 C were approx. 10 12 cm -3 . It was found that these residual deep-level defects observed by DLTS were inefficient generation-recombination centres since the reverse current was independent of the RTA temperatures. (author)

Residual energy deposition in dental enamel during IR laser ablation at 2.79, 2.94, 9.6, and 10.6 μm

Science.gov (United States)

Ragadio, Jerome N.; Lee, Christian K.; Fried, Daniel

2000-03-01

The objective of this study was to measure the residual heat deposition during laser ablation at those IR laser wavelengths best suited for the removal of dental caries. The principal factor limiting the rate of laser ablation of dental hard tissue is the risk of excessive heat accumulation in the tooth, which has the potential for causing damage to the pulp. Optimal laser ablation systems minimize the residual energy deposition in the tooth by transferring deposited laser energy to kinetic and internal energy of ejected tissue components. The residual heat deposition in the tooth was measured at laser wavelengths of 2.79, 2.94, 9.6 and 10.6 micrometer and pulse widths of 150 ns - 150 microsecond(s) . The residual energy was at a minimum for fluences well above the ablation threshold where it saturates at values from 25 - 70% depending on pulse duration and wavelength for the systems investigated. The lowest values of the residual energy were measured for short (less than 20 microseconds) CO2 laser pulses at 9.6 micrometer and for Q-switched erbium laser pulses. This work was supported by NIH/NIDCR R29DE12091 and the Center for Laser Applications in Medicine, DOE DEFG0398ER62576.

Characterization of Hospital Residuals

International Nuclear Information System (INIS)

Blanco Meza, A.; Bonilla Jimenez, S.

1997-01-01

The main objective of this investigation is the characterization of the solid residuals. A description of the handling of the liquid and gassy waste generated in hospitals is also given, identifying the source where they originate. To achieve the proposed objective the work was divided in three stages: The first one was the planning and the coordination with each hospital center, in this way, to determine the schedule of gathering of the waste can be possible. In the second stage a fieldwork was made; it consisted in gathering the quantitative and qualitative information of the general state of the handling of residuals. In the third and last stage, the information previously obtained was organized to express the results as the production rate per day by bed, generation of solid residuals for sampled services, type of solid residuals and density of the same ones. With the obtained results, approaches are settled down to either determine design parameters for final disposition whether for incineration, trituration, sanitary filler or recycling of some materials, and storage politics of the solid residuals that allow to determine the gathering frequency. The study concludes that it is necessary to improve the conditions of the residuals handling in some aspects, to provide the cleaning personnel of the equipment for gathering disposition and of security, minimum to carry out this work efficiently, and to maintain a control of all the dangerous waste, like sharp or polluted materials. In this way, an appreciable reduction is guaranteed in the impact on the atmosphere. (Author) [es

Damage Tolerance Assessment of Friction Pull Plug Welds in an Aluminum Alloy

Science.gov (United States)

McGill, Preston; Burkholder, Jonathan

2012-01-01

Friction stir welding is a solid state welding process used in the fabrication of cryogenic propellant tanks. Self-reacting friction stir welding is one variation of the friction stir weld process being developed for manufacturing tanks. Friction pull plug welding is used to seal the exit hole that remains in a circumferential self-reacting friction stir weld. A friction plug weld placed in a self-reacting friction stir weld results in a non-homogenous weld joint where the initial weld, plug weld, their respective heat affected zones and the base metal all interact. The welded joint is a composite plastically deformed material system with a complex residual stress field. In order to address damage tolerance concerns associated with friction plug welds in safety critical structures, such as propellant tanks, nondestructive inspection and proof testing may be required to screen hardware for mission critical defects. The efficacy of the nondestructive evaluation or the proof test is based on an assessment of the critical flaw size. Test data relating residual strength capability to flaw size in an aluminum alloy friction plug weld will be presented.

Applications of bauxite residue: A mini-review.

Science.gov (United States)

Verma, Ajay S; Suri, Narendra M; Kant, Suman

2017-10-01

Bauxite residue is the waste generated during alumina production by Bayer's process. The amount of bauxite residue (40-50 wt%) generated depends on the quality of bauxite ore used for the processing. High alkalinity and high caustic content in bauxite residue causes environmental risk for fertile soil and ground water contamination. The caustic (NaOH) content in bauxite residue leads to human health risks, like dermal problems and irritation to eyes. Moreover, disposal of bauxite residue requires a large area; such problems can only be minimised by utilising bauxite residue effectively. For two decades, bauxite residue has been used as a binder in cement industries and filler/reinforcement for composite materials in the automobile industry. Valuable metals and oxides, like alumina (Al 2 O 3 ), titanium oxide (TiO 2 ) and iron oxide Fe 2 O 3 , were extracted from bauxite residue to reduce waste. Bauxite residue was utilised in construction and structure industries to make geopolymers. It was also used in the making of glass-ceramics and a coating material. Recently bauxite residue has been utilised to extract rare earth elements like scandium (Sc), yttrium (Y), lanthanum (La), cerium (Ce), neodymium (Nd) and dysprosium (Dy). In this review article, the mineralogical characteristics of bauxite residue are summarised and current progresses on utilisation of bauxite residue in different fields of science and engineering are presented in detail.

Management of NORM Residues

International Nuclear Information System (INIS)

2013-06-01

The IAEA attaches great importance to the dissemination of information that can assist Member States in the development, implementation, maintenance and continuous improvement of systems, programmes and activities that support the nuclear fuel cycle and nuclear applications, and that address the legacy of past practices and accidents. However, radioactive residues are found not only in nuclear fuel cycle activities, but also in a range of other industrial activities, including: - Mining and milling of metalliferous and non-metallic ores; - Production of non-nuclear fuels, including coal, oil and gas; - Extraction and purification of water (e.g. in the generation of geothermal energy, as drinking and industrial process water; in paper and pulp manufacturing processes); - Production of industrial minerals, including phosphate, clay and building materials; - Use of radionuclides, such as thorium, for properties other than their radioactivity. Naturally occurring radioactive material (NORM) may lead to exposures at some stage of these processes and in the use or reuse of products, residues or wastes. Several IAEA publications address NORM issues with a special focus on some of the more relevant industrial operations. This publication attempts to provide guidance on managing residues arising from different NORM type industries, and on pertinent residue management strategies and technologies, to help Member States gain perspectives on the management of NORM residues

Immobilization of acid digestion residue

International Nuclear Information System (INIS)

Greenhalgh, W.O.; Allen, C.R.

1983-01-01

Acid digestion treatment of nuclear waste is similar to incineration processes and results in the bulk of the waste being reduced in volume and weight to some residual solids termed residue. The residue is composed of various dispersible solid materials and typically contains the resultant radioactivity from the waste. This report describes the immobilization of the residue in portland cement, borosilicate glass, and some other waste forms. Diagrams showing the cement and glass virtification parameters are included in the report as well as process steps and candidate waste product forms. Cement immobilization is simplest and probably least expensive; glass vitrification exhibits the best overall volume reduction ratio