WorldWideScience

Sample records for reserve spr requires

  1. Three dimensional simulation for bayou choctaw strategic petroleum reserve (SPR).

    Energy Technology Data Exchange (ETDEWEB)

    Ehgartner, Brian L. (Sandia National Laboratories, Albuquerque, NM); Park, Byoung Yoon; Lee, Moo Yul

    2006-12-01

    Three dimensional finite element analyses were performed to evaluate the structural integrity of the caverns located at the Bayou Choctaw (BC) site which is considered a candidate for expansion. Fifteen active and nine abandoned caverns exist at BC, with a total cavern volume of some 164 MMB. A 3D model allowing control of each cavern individually was constructed because the location and depth of caverns and the date of excavation are irregular. The total cavern volume has practical interest, as this void space affects total creep closure in the BC salt mass. Operations including both cavern workover, where wellhead pressures are temporarily reduced to atmospheric, and cavern enlargement due to leaching during oil drawdowns that use water to displace the oil from the caverns, were modeled to account for as many as the five future oil drawdowns in the six SPR caverns. The impacts on cavern stability, underground creep closure, surface subsidence, infrastructure, and well integrity were quantified.

  2. Strategic Petroleum Reserve (SPR) additional geologic site characterization studies, Bryan Mound Salt Dome, Texas

    Energy Technology Data Exchange (ETDEWEB)

    Neal, J.T. [Sandia National Labs., Albuquerque, NM (United States); Magorian, T.R.; Ahmad, S. [Acres International Corp., Amherst, NY (United States)

    1994-11-01

    This report revises the original report that was published in 1980. Some of the topics covered in the earlier report were provisional and it is now practicable to reexamine them using new or revised geotechnical data and that obtained from SPR cavern operations, which involves 16 new caverns. Revised structure maps and sections show interpretative differences as compared with the 1980 report and more definition in the dome shape and caprock structural contours, especially a major southeast-northwest trending anomalous zone. The original interpretation was of westward tilt of the dome, this revision shows a tilt to the southeast, consistent with other gravity and seismic data. This interpretation refines the evaluation of additional cavern space, by adding more salt buffer and allowing several more caverns. Additional storage space is constrained on this nearly full dome because of low-lying peripheral wetlands, but 60 MMBBL or more of additional volume could be gained in six or more new caverns. Subsidence values at Bryan Mound are among the lowest in the SPR system, averaging about 11 mm/yr (0.4 in/yr), but measurement and interpretation issues persist, as observed values are about the same as survey measurement accuracy. Periodic flooding is a continuing threat because of the coastal proximity and because peripheral portions of the site are at elevations less than 15 ft. This threat may increase slightly as future subsidence lowers the surface, but the amount is apt to be small. Caprock integrity may be affected by structural features, especially the faulting associated with anomalous zones. Injection wells have not been used extensively at Bryan Mound, but could be a practicable solution to future brine disposal needs. Environmental issues center on the areas of low elevation that are below 15 feet above mean sea level: the coastal proximity and lowland environment combined with the potential for flooding create conditions that require continuing surveillance.

  3. Strategic Petroleum Reserve (SPR) additional geologic site characterization studies, Bayou Choctaw salt dome, Louisiana

    Energy Technology Data Exchange (ETDEWEB)

    Neal, J.T. [Sandia National Labs., Albuquerque, NM (United States); Magorian, T.R. [Magorian (Thomas R.), Amherst, NY (United States); Byrne, K.O.; Denzler, S. [Acres International Corp., Amherst, NY (United States)

    1993-09-01

    This report revises and updates the geologic site characterization report that was published in 1980. Revised structure maps and sections show interpretative differences in the dome shape and caprock structural contours, especially a major east-west trending shear zone, not mapped in the 1980 report. Excessive gas influx in Caverns 18 and 20 may be associated with this shear zone. Subsidence values at Bayou Choctaw are among the lowest in the SPR system, averaging only about 10 mm/yr but measurement and interpretation issues persist, as observed values often approximate measurement accuracy. Periodic, temporary flooding is a continuing concern because of the low site elevation (less than 10 ft), and this may intensify as future subsidence lowers the surface even further. Cavern 4 was re-sonared in 1992 and the profiles suggest that significant change has not occurred since 1980, thereby reducing the uncertainty of possible overburden collapse -- as occurred at Cavern 7 in 1954. Other potential integrity issues persist, such as the proximity of Cavern 20 to the dome edge, and the narrow web separating Caverns 15 and 17. Injection wells have been used for the disposal of brine but have been only marginally effective thus far; recompletions into more permeable lower Pleistocene gravels may be a practical way of increasing injection capacity and brinefield efficiency. Cavern storage space is limited on this already crowded dome, but 15 MMBBL could be gained by enlarging Cavern 19 and by constructing a new cavern beneath and slightly north of abandoned Cavern 13. Environmental issues center on the low site elevation: the backswamp environment combined with the potential for periodic flooding create conditions that will require continuing surveillance.

  4. Differential SPR immunosensing

    NARCIS (Netherlands)

    Berger, Charles E.H.; Berger, C.E.H.; Greve, Jan

    2000-01-01

    In this work we describe a surface plasmon resonance (SPR) sensor with a differential detection of the SPR angle, and demonstrate it. The angle of incidence is modulated by a simple piezo-electric actuator, and the reflectance signal is measured with a lockin-amplifier. When the conditions for SPR

  5. SPR 2015. Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-04-01

    The volume contains the abstracts of the SPR (society for pediatric radiology) 2015 meeting covering the following issues: fetal imaging, muscoskeletal imaging, cardiac imaging, chest imaging, oncologic imaging, tools for process improvement, child abuse, contrast enhanced ultrasound, image gently - update of radiation dose recording/reporting/monitoring - meaningful or useless meaning?, pediatric thoracic imaging, ALARA.

  6. 76 FR 64250 - Reserve Requirements of Depository Institutions: Reserves Simplification and Private Sector...

    Science.gov (United States)

    2011-10-18

    ... D; Docket No. R-1433] RIN No. 7100 AD 83 Reserve Requirements of Depository Institutions: Reserves Simplification and Private Sector Adjustment Factor AGENCY: Board of Governors of the Federal Reserve System... public comment on proposed amendments to Regulation D, Reserve Requirements of Depository Institutions...

  7. 12 CFR 204.4 - Computation of required reserves.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Computation of required reserves. 204.4 Section... RESERVE REQUIREMENTS OF DEPOSITORY INSTITUTIONS (REGULATION D) § 204.4 Computation of required reserves... liabilities during a 14-day computation period ending every second Monday. (e) For institutions that file a...

  8. Walks on SPR neighborhoods.

    Science.gov (United States)

    Caceres, Alan Joseph J; Castillo, Juan; Lee, Jinnie; St John, Katherine

    2013-01-01

    A nearest-neighbor-interchange (NNI)-walk is a sequence of unrooted phylogenetic trees, T1, T2, . . . , T(k) where each consecutive pair of trees differs by a single NNI move. We give tight bounds on the length of the shortest NNI-walks that visit all trees in a subtree-prune-and-regraft (SPR) neighborhood of a given tree. For any unrooted, binary tree, T, on n leaves, the shortest walk takes Θ(n²) additional steps more than the number of trees in the SPR neighborhood. This answers Bryant’s Second Combinatorial Challenge from the Phylogenetics Challenges List, the Isaac Newton Institute, 2011, and the Penny Ante Problem List, 2009.

  9. SPR 2014. Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-05-15

    The proceedings of the SPR 2014 meeting include abstracts on the following topics: Body imaging techniques: practical advice for clinic work; thoracic imaging: focus on the lungs; gastrointestinal imaging: focus on the pancreas and bowel; genitourinary imaging: focus on gonadal radiology; muscoskeletal imaging; focus on oncology; child abuse and nor child abuse: focus on radiography; impact of NMR and CT imaging on management of CHD; education and communication: art and practice in pediatric radiology.

  10. SPR 2014. Abstracts

    International Nuclear Information System (INIS)

    2014-01-01

    The proceedings of the SPR 2014 meeting include abstracts on the following topics: Body imaging techniques: practical advice for clinic work; thoracic imaging: focus on the lungs; gastrointestinal imaging: focus on the pancreas and bowel; genitourinary imaging: focus on gonadal radiology; muscoskeletal imaging; focus on oncology; child abuse and nor child abuse: focus on radiography; impact of NMR and CT imaging on management of CHD; education and communication: art and practice in pediatric radiology.

  11. SPR 2017. Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2017-05-15

    The conference proceedings SPR 2017 include abstracts on the following issues: gastrointestinal radiography - inflammatory bowel diseases, cardiovascular CTA, general muscoskeletal radiology, muscoskeletal congenital development diseases, general pediatric radiology - chest, muscoskeletal imaging - marrow and infectious disorders, state-of-the-art body MR imaging, practical pediatric sonography, quality and professionalism, CT imaging in congenital heart diseases, radiographic courses, body MT techniques, contrast enhanced ultrasound, machine learning, forensic imaging, the radiation dos conundrum - reconciling imaging, imagining and managing, the practice of radiology, interventional radiology, neuroradiology, PET/MR.

  12. 25 CFR 141.5 - Reservation business license required.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Reservation business license required. 141.5 Section 141.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES BUSINESS PRACTICES ON THE NAVAJO, HOPI AND ZUNI RESERVATIONS Licensing Requirements and Procedures § 141.5...

  13. How required reserve ratio affects distribution and velocity of money

    Science.gov (United States)

    Xi, Ning; Ding, Ning; Wang, Yougui

    2005-11-01

    In this paper the dependence of wealth distribution and the velocity of money on the required reserve ratio is examined based on a random transfer model of money and computer simulations. A fractional reserve banking system is introduced to the model where money creation can be achieved by bank loans and the monetary aggregate is determined by the monetary base and the required reserve ratio. It is shown that monetary wealth follows asymmetric Laplace distribution and latency time of money follows exponential distribution. The expression of monetary wealth distribution and that of the velocity of money in terms of the required reserve ratio are presented in a good agreement with simulation results.

  14. How Required Reserve Ratio Affects Distribution and Velocity of Money

    OpenAIRE

    Xi, Ning; Ding, Ning; Wang, Yougui

    2005-01-01

    In this paper the dependence of wealth distribution and the velocity of money on the required reserve ratio is examined based on a random transfer model of money and computer simulations. A fractional reserve banking system is introduced to the model where money creation can be achieved by bank loans and the monetary aggregate is determined by the monetary base and the required reserve ratio. It is shown that monetary wealth follows asymmetric Laplace distribution and latency time of money fo...

  15. Real-time ligation chain reaction for DNA quantification and identification on the FO-SPR.

    Science.gov (United States)

    Knez, Karel; Spasic, Dragana; Delport, Filip; Lammertyn, Jeroen

    2015-05-15

    Different assays have been developed in the past years to meet point-of-care diagnostic tests requirements for fast and sensitive quantification and identification of targets. In this paper, we developed the ligation chain reaction (LCR) assay on the Fiber Optic Surface Plasmon Resonance (FO-SPR) platform, which enabled simultaneous quantification and cycle-to-cycle identification of DNA during amplification. The newly developed assay incorporated FO-SPR DNA melting assay, previously developed by our group. This required establishment of several assay parameters, including buffer ionic strength and thermal ramping speed as these parameters both influence the ligation enzyme performance and the hybridization yield of the gold nanoparticles (Au NPs) on the FO-SPR sensor. Quantification and identification of DNA targets was achieved over a wide concentration range with a calibration curve spanning 7 orders of magnitude and LOD of 13.75 fM. Moreover, the FO-SPR LCR assay could discriminate single nucleotide polymorphism (SNPs) without any post reaction analysis, featuring thus all the essential requirements of POC tests. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Use and Limitations of the Reserve Requirement Policy in Montenegro

    Directory of Open Access Journals (Sweden)

    Milošević Velibor

    2014-05-01

    Full Text Available Since reserve requirement is the only monetary policy instrument used in Montenegro, it has been subject to frequent amendments since the global crisis outbreak. The analysis of the monetary demand model showed that there is an active transmission mechanism of change in the reserve requirement rate on the deposits trend reflects on lending activity. Also, there is a significant impact of FDIs on deposits trending in the banking system, as well as the positive impact of turnover on stock exchange on the deposits and loans trend. Finally, it was found that the financial crisis has caused negative trends in loans and deposits. On the other hand, the impact of changes in the reserve requirement on the economic activity in Montenegro could not be determined. This is primarily due to the fact that the transmission mechanism of the effect of reserve requirement on economic activity is too long to be able to estimate the model that does not allow the dynamics of the independent variables. The second reason is that industrial output index is only an indirect indicator of the economic activity.

  17. 40 CFR 410.02 - Monitoring requirements. [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Monitoring requirements. [Reserved] 410.02 Section 410.02 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS TEXTILE MILLS POINT SOURCE CATEGORY General Provisions § 410.02 Monitoring...

  18. Analysis of SPR salt cavern remedial leach program 2013.

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Paula D.; Gutierrez, Karen A.; Lord, David L.; Rudeen, David Keith

    2013-09-01

    The storage caverns of the US Strategic Petroleum Reserve (SPR) exhibit creep behavior resulting in reduction of storage capacity over time. Maintenance of oil storage capacity requires periodic controlled leaching named remedial leach. The 30 MMB sale in summer 2011 provided space available to facilitate leaching operations. The objective of this report is to present the results and analyses of remedial leach activity at the SPR following the 2011 sale until mid-January 2013. This report focuses on caverns BH101, BH104, WH105 and WH106. Three of the four hanging strings were damaged resulting in deviations from normal leach patterns; however, the deviations did not affect the immediate geomechanical stability of the caverns. Significant leaching occurred in the toes of the caverns likely decreasing the number of available drawdowns until P/D ratio criteria are met. SANSMIC shows good agreement with sonar data and reasonably predicted the location and size of the enhanced leaching region resulting from string breakage.

  19. Wind Farms’ Spatial Distribution Effect on Power System Reserves Requirements

    DEFF Research Database (Denmark)

    Sørensen, Poul Ejnar; Cutululis, Nicolaos Antonio

    2010-01-01

    The wind power development during last millennium was typically based on small wind turbines dispersed over large areas, leading to a significant smoothing of the wind power fluctuations in a power system balancing area. The present development goes towards much larger wind farms, concentrated...... in smaller areas, which causes the total wind power fluctuations in power system areas to increase significantly. The impact of future large wind farms spatial distribution with respect to the power system reserve requirements is analyzed in this paper. For this purpose, Correlated Wind (CorWind) power time...... series simulation model developed to simulate wind power variability over a large area is used. As a study case, two scenarios for short term offshore wind power development in the West Danish power system region are used. The first scenario assumes that all the wind farms are built in the region...

  20. Changing the VP Reserve Readiness System to Match the Crew-Coordination Requirements of Reserve Aircrews

    National Research Council Canada - National Science Library

    Woods, William

    1997-01-01

    .... The current VP readiness system promotes long-term, fixed crews with TACNUC rules. Adhering to these crew composition rules can cause considerable scheduling difficulties for reserve squadrons...

  1. 12 CFR 204.7 - Supplemental reserve requirement.

    Science.gov (United States)

    2010-01-01

    ... to increase the amount of reserves maintained to a level essential for the conduct of monetary policy... Bank Board, and the National Credit Union Administration Board, the Board may impose a supplemental... reserve ratios established by the Monetary Control Act of 1980 (Pub. L. 96-221) in effect on September 1...

  2. 7 CFR 985.57 - Reserve pool requirements.

    Science.gov (United States)

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE MARKETING ORDER REGULATING THE... commercial trade practices. The Committee shall designate a Committee employee as reserve pool manager. (b...

  3. Reform of reserve requirements for nuclear decommissioning, dismantling and disposal

    International Nuclear Information System (INIS)

    Meyer, Bettina; Kuechler, Swantje; Wronski, Rupert

    2015-01-01

    This article reports on the ongoing intense discussion as to whether the financial reserves of nuclear power plant operators are sufficient. It starts out with an overview of the current scientific and political debate. This is followed by a brief analysis of nuclear financial reserves in 2014 and preceding years. The authors then present the reform concept of the Forum Oekologisch-Soziale Marktwirtschaft (FOes) and go on to compare it with concepts from the political realm.

  4. SP-R210 (Myo18A Isoforms as Intrinsic Modulators of Macrophage Priming and Activation.

    Directory of Open Access Journals (Sweden)

    Linlin Yang

    Full Text Available The surfactant protein (SP-A receptor SP-R210 has been shown to increase phagocytosis of SP-A-bound pathogens and to modulate cytokine secretion by immune cells. SP-A plays an important role in pulmonary immunity by enhancing opsonization and clearance of pathogens and by modulating macrophage inflammatory responses. Alternative splicing of the Myo18A gene results in two isoforms: SP-R210S and SP-R210L, with the latter predominantly expressed in alveolar macrophages. In this study we show that SP-A is required for optimal expression of SP-R210L on alveolar macrophages. Interestingly, pre-treatment with SP-A prepared by different methods either enhances or suppresses responsiveness to LPS, possibly due to differential co-isolation of SP-B or other proteins. We also report that dominant negative disruption of SP-R210L augments expression of receptors including SR-A, CD14, and CD36, and enhances macrophages' inflammatory response to TLR stimulation. Finally, because SP-A is known to modulate CD14, we used a variety of techniques to investigate how SP-R210 mediates the effect of SP-A on CD14. These studies revealed a novel physical association between SP-R210S, CD14, and SR-A leading to an enhanced response to LPS, and found that SP-R210L and SP-R210S regulate internalization of CD14 via distinct macropinocytosis-like mechanisms. Together, our findings support a model in which SP-R210 isoforms differentially regulate trafficking, expression, and activation of innate immune receptors on macrophages.

  5. Features of Bayou Choctaw SPR caverns and internal structure of the salt dome.

    Energy Technology Data Exchange (ETDEWEB)

    Munson, Darrell E.

    2007-07-01

    The intent of this study is to examine the internal structure of the Bayou Choctaw salt dome utilizing the information obtained from graphical representations of sonar survey data of the internal cavern surfaces. Many of the Bayou Choctaw caverns have been abandoned. Some existing caverns were purchased by the Strategic Petroleum Reserve (SPR) program and have rather convoluted histories and complex cavern geometries. In fact, these caverns are typically poorly documented and are not particularly constructive to this study. Only two Bayou Choctaw caverns, 101 and 102, which were constructed using well-controlled solutioning methods, are well documented. One of these was constructed by the SPR for their use while the other was constructed and traded for another existing cavern. Consequently, compared to the SPR caverns of the West Hackberry and Big Hill domes, it is more difficult to obtain a general impression of the stratigraphy of the dome. Indeed, caverns of Bayou Choctaw show features significantly different than those encountered in the other two SPR facilities. In the number of abandoned caverns, and some of those existing caverns purchased by the SPR, extremely irregular solutioning has occurred. The two SPR constructed caverns suggest that some sections of the caverns may have undergone very regular solutioning to form uniform cylindrical shapes. Although it is not usually productive to speculate, some suggestions that point to the behavior of the Bayou Choctaw dome are examined. Also the primary differences in the Bayou Choctaw dome and the other SPR domes are noted.

  6. SPR: Uma nova ferramenta para biossensores

    Directory of Open Access Journals (Sweden)

    Carvalho Rosangela M. de

    2003-01-01

    Full Text Available This paper reviewed the development and theoretical aspects of surface plasmon ressonance (SPR technique and discusses this powerful sensor technology in the development of biosensors, as well as for the investigation of biological interactions and clinical assays. The SPR has been proven to be a valuable tool to investigate dynamic processes, such as adsorption, degradation, determination of dieletric properties, association/dissociation kinetics, affinity constants of specific ligand-ligate interactions, allowing real-time analysis at almost any surface. The SPR as a complementary technique alongside electrochemical methods is also presented.

  7. Improving Deterministic Reserve Requirements for Security Constrained Unit Commitment and Scheduling Problems in Power Systems

    Science.gov (United States)

    Wang, Fengyu

    Traditional deterministic reserve requirements rely on ad-hoc, rule of thumb methods to determine adequate reserve in order to ensure a reliable unit commitment. Since congestion and uncertainties exist in the system, both the quantity and the location of reserves are essential to ensure system reliability and market efficiency. The modeling of operating reserves in the existing deterministic reserve requirements acquire the operating reserves on a zonal basis and do not fully capture the impact of congestion. The purpose of a reserve zone is to ensure that operating reserves are spread across the network. Operating reserves are shared inside each reserve zone, but intra-zonal congestion may block the deliverability of operating reserves within a zone. Thus, improving reserve policies such as reserve zones may improve the location and deliverability of reserve. As more non-dispatchable renewable resources are integrated into the grid, it will become increasingly difficult to predict the transfer capabilities and the network congestion. At the same time, renewable resources require operators to acquire more operating reserves. With existing deterministic reserve requirements unable to ensure optimal reserve locations, the importance of reserve location and reserve deliverability will increase. While stochastic programming can be used to determine reserve by explicitly modelling uncertainties, there are still scalability as well as pricing issues. Therefore, new methods to improve existing deterministic reserve requirements are desired. One key barrier of improving existing deterministic reserve requirements is its potential market impacts. A metric, quality of service, is proposed in this thesis to evaluate the price signal and market impacts of proposed hourly reserve zones. Three main goals of this thesis are: 1) to develop a theoretical and mathematical model to better locate reserve while maintaining the deterministic unit commitment and economic dispatch

  8. Observations on vapor pressure in SPR caverns : sources.

    Energy Technology Data Exchange (ETDEWEB)

    Munson, Darrell Eugene

    2010-05-01

    The oil of the Strategic Petroleum Reserve (SPR) represents a national response to any potential emergency or intentional restriction of crude oil supply to this country, and conforms to International Agreements to maintain such a reserve. As assurance this reserve oil will be available in a timely manner should a restriction in supply occur, the oil of the reserve must meet certain transportation criteria. The transportation criteria require that the oil does not evolve dangerous gas, either explosive or toxic, while in the process of transport to, or storage at, the destination facility. This requirement can be a challenge because the stored oil can acquire dissolved gases while in the SPR. There have been a series of reports analyzing in exceptional detail the reasons for the increases, or regains, in gas content; however, there remains some uncertainty in these explanations and an inability to predict why the regains occur. Where the regains are prohibitive and exceed the criteria, the oil must undergo degasification, where excess portions of the volatile gas are removed. There are only two known sources of gas regain, one is the salt dome formation itself which may contain gas inclusions from which gas can be released during oil processing or storage, and the second is increases of the gases release by the volatile components of the crude oil itself during storage, especially if the stored oil undergoes heating or is subject to biological generation processes. In this work, the earlier analyses are reexamined and significant alterations in conclusions are proposed. The alterations are based on how the fluid exchanges of brine and oil uptake gas released from domal salt during solutioning, and thereafter, during further exchanges of fluids. Transparency of the brine/oil interface and the transfer of gas across this interface remains an important unanswered question. The contribution from creep induced damage releasing gas from the salt surrounding the cavern is

  9. Strategic Petroleum Reserve site environmental report for calendar year 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    The purpose of this Site Environmental Report (SER) is to characterize site environmental management performance, confirm compliance with environmental standards and requirements, and highlight significant programs and efforts for the US Department of Energy (DOE) Strategic Petroleum Reserve (SPR). The SER, provided annually in accordance with DOE order 5400.1, serves the public by summarizing monitoring data collected to assess how the SPR impacts the environment. The SER provides a balanced synopsis of non-radiological monitoring and regulatory compliance data and affirms that the SPR has been operating within acceptable regulatory limits. Included in this report is a describe of each site`s environment, an overview of the SPR environmental program, and a recapitulation of special environmental activities and events associated with each SPR site during 1997. Two of these highlights include decommissioning of the Weeks Island site, involving the disposition of 11.6 million m{sup 3} (73 million barrels) of crude oil inventory, as well as the degasification of over 12.6 million m{sup 3} (79.3 million barrels) of crude oil inventory at the Big Hill and Bryan Mound facilities.

  10. Strategic Petroleum Reserve site environmental report for calendar year 1997

    International Nuclear Information System (INIS)

    1998-01-01

    The purpose of this Site Environmental Report (SER) is to characterize site environmental management performance, confirm compliance with environmental standards and requirements, and highlight significant programs and efforts for the US Department of Energy (DOE) Strategic Petroleum Reserve (SPR). The SER, provided annually in accordance with DOE order 5400.1, serves the public by summarizing monitoring data collected to assess how the SPR impacts the environment. The SER provides a balanced synopsis of non-radiological monitoring and regulatory compliance data and affirms that the SPR has been operating within acceptable regulatory limits. Included in this report is a describe of each site's environment, an overview of the SPR environmental program, and a recapitulation of special environmental activities and events associated with each SPR site during 1997. Two of these highlights include decommissioning of the Weeks Island site, involving the disposition of 11.6 million m 3 (73 million barrels) of crude oil inventory, as well as the degasification of over 12.6 million m 3 (79.3 million barrels) of crude oil inventory at the Big Hill and Bryan Mound facilities

  11. 25 CFR 141.7 - Bond requirement for a reservation business.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Bond requirement for a reservation business. 141.7 Section 141.7 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES BUSINESS PRACTICES ON THE NAVAJO, HOPI AND ZUNI RESERVATIONS Licensing Requirements and Procedures § 141.7 Bond...

  12. Mini-SOL Språka och Lek

    DEFF Research Database (Denmark)

    Bylander, Helle Iben

    Ju tidigare man börjar med en medveten språklig stimulering, desto bättre är det. I denna praktiska handbok finns pedagogiska tips och lekar för de allra yngsta barnen (0–3 år). Boken är sprängfull av roliga aktiviteter som alla stimulerar språkutvecklingen. Mini-SOL följer de språkliga områdena...

  13. 12 CFR 204.136 - Treatment of trust overdrafts for reserve requirement reporting purposes.

    Science.gov (United States)

    2010-01-01

    ... transfer, the trust department's normal posting procedures may not reflect receipt of the cash collateral... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Treatment of trust overdrafts for reserve...) Interpretations § 204.136 Treatment of trust overdrafts for reserve requirement reporting purposes. (a) Authority...

  14. Report to the Congress on alternative methods for the Strategic Petroleum Reserve

    Energy Technology Data Exchange (ETDEWEB)

    1990-02-01

    The purpose of this study is to fulfill the requirements of Public Law No. 101-46, approved June 30, 1989. The study describes and evaluates alternative methods for financing the future expansion of the Strategic petroleum Reserve (SPR), both to the current target level of 750 million barrels and to potential future levels of up to one billion barrels.

  15. SPR detection of cardiac troponin T for acute myocardial infarction.

    Science.gov (United States)

    Pawula, Maria; Altintas, Zeynep; Tothill, Ibtisam E

    2016-01-01

    A surface plasmon resonance (SPR) sensor developed for the rapid, sensitive and specific detection of cardiac troponin T (cTnT) in serum samples is reported in this work. An extensive optimisation of assay parameters was conducted to achieve optimal detection strategy. Both direct and sandwich immunoassay formats were investigated and optimised. The response obtained was enhanced further by the use of gold nanoparticles (AuNPs) conjugated to the anti-cTnT detection antibody. A regeneration method was developed to enable the reuse of the SPR sensor for multiple sample application. The SPR immunosensor showed good reproducibility for cTnT detection in the concentration range of 25-1000 ng mL(-1) and 5-400 ng mL(-1) for the direct and sandwich assays in buffer, respectively. The linear regression analysis was performed and R(2) value was found as 0.99 for both assays. In order to optimise the sensor for serum analysis, nonspecific binding of serum proteins was reduced through the use of additives in the dilution buffer. To achieve greater sensitivity, the performance of the cTnT immunosensor sandwich assay in human serum was evaluated using non-modified and AuNP modified detector antibodies. A detection limit (LOD) for the immunosensor in 50% serum was assessed as 5 ng mL(-1) cTnT for the standard sandwich assay and 0.5 ng mL(-1) cTnT when using AuNP conjugated detector antibodies with a linear dynamic range of 0.5-40 ng mL(-1). The dissociation constant was found as 3.28 × 10(-9) M using Langmuir binding model which indicates high affinity between cTnT and its antibody. The proposed SPR immunosensor has a promising potential to be developed for point-of-care testing for the early diagnosis of acute myocardial infarction (AMI). This method can also be used for the rapid detection of biomarkers in central nervous system diseases. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Metakognisjon om språk og språklæring i et flerspråklighetsperspektiv

    Directory of Open Access Journals (Sweden)

    Åsta Haukås

    2014-09-01

    Full Text Available I denne artikkelen drøfter jeg betydningen av elevers refleksjon om språk og språklæring. Artikkelens første del gir en kort introduksjon til forskningsfeltet metakognisjon. Deretter presenterer jeg to underkategorier av metakognisjon som er særlig relevante i språkundervisningen, metalingvistisk bevissthet og bevissthet om språklæringsstrategier. I artikkelens andre del introduserer jeg hovedprinsippene i flerspråklighetsdidaktikken, gir eksempler på hvordan elevene kan reflektere over språk og språklæring i språkfagene og argumenterer for at økt vekt på metakognisjon i og på tvers av språkfagene er en nøkkel til bedre språkkompetanse hos fremtidige elever. Dette krever imidlertid et sterkere samarbeid mellom språkfagene i skole, lærerutdanning og forskning.

  17. 21 CFR 111.465 - What requirements apply to holding reserve samples of dietary supplements?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What requirements apply to holding reserve samples of dietary supplements? 111.465 Section 111.465 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CURRENT GOOD MANUFACTURING...

  18. 21 CFR 111.83 - What are the requirements for reserve samples?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What are the requirements for reserve samples? 111.83 Section 111.83 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN MANUFACTURING...

  19. Analysis of cavern stability at the Bryan Mound SPR site.

    Energy Technology Data Exchange (ETDEWEB)

    Ehgartner, Brian L.; Sobolik, Steven Ronald

    2009-04-01

    This report presents computational analyses that simulate the structural response of caverns at the Strategic Petroleum Reserve Bryan Mound site. The cavern field comprises 20 caverns. Five caverns (1, 2, 4, and 5; 3 was later plugged and abandoned) were acquired from industry and have unusual shapes and a history dating back to 1946. The other 16 caverns (101-116) were leached according to SPR standards in the mid-1980s and have tall cylindrical shapes. The history of the caverns and their shapes are simulated in a 3-D geomechanics model of the site that predicts deformations, strains, and stresses. Future leaching scenarios due to oil drawdowns using fresh water are also simulated by increasing the volume of the caverns. Cavern pressures are varied in the model to capture operational practices in the field. The results of the finite element model are interpreted to provide information on the current and future status of subsidence, well integrity, and cavern stability. The most significant result in this report is relevant to caverns 1, 2, and 5. The caverns have non-cylindrical shapes and have potential regions where the surrounding salt may be damaged during workover procedures. During a workover the normal cavern operating pressure is lowered to service a well. At this point the wellhead pressures are atmospheric. When the workover is complete, the cavern is repressurized. The resulting elastic stresses are sufficient to cause tension and large deviatoric stresses at several locations. With time, these stresses relax to a compressive state due to salt creep. However, the potential for salt damage and fracturing exists. The analyses predict tensile stresses at locations with sharp-edges in the wall geometry, or in the case of cavern 5, in the neck region between the upper and lower lobes of the cavern. The effects do not appear to be large-scale, however, so the only major impact is the potential for stress-induced salt falls in cavern 5, potentially leading to

  20. Historical Cavern Floor Rise for All SPR Sites

    Energy Technology Data Exchange (ETDEWEB)

    Moriarty, Dylan Michael [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-09-01

    The Strategic Petroleum Reserve (SPR) contains the largest supply is the largest stockpile of government-owned emergency crude oil in the world. The oil is stored in multiple salt caverns spread over four sites in Louisiana and Texas. Cavern infrastructure near the bottom of the cavern can be damaged from vertical floor movement. This report presents a comprehensive history of floor movements in each cavern. Most of the cavern floor rise rates ranged from 0.5-3.5 ft/yr, however, there were several caverns with much higher rise rates. BH103, BM106, and BH105 had the three highest rise rates. Information from this report will be used to better predict future vertical floor movements and optimally place cavern infrastructure. The reasons for floor rise are not entirely understood and should be investigated.

  1. Pleiotropic Regulation of Virulence Genes in Streptococcus mutans by the Conserved Small Protein SprV.

    Science.gov (United States)

    Shankar, Manoharan; Hossain, Mohammad S; Biswas, Indranil

    2017-04-15

    critical for successful disease establishment. Sometimes these regulators, which are potential targets for antimicrobials, are lost in the genomic context due to the lack of annotated homologs. This work outlines the regulatory impact of a small, highly conserved hypothetical protein, SprV, encoded by S. mutans We show that SprV affects the transcript levels of various virulence factors required for normal growth, biofilm formation, stress tolerance, genetic competence, and bacteriocin production. Copyright © 2017 American Society for Microbiology.

  2. Assessment of the Available Drawdowns for Oil Storage Caverns at the West Hackberry SPR Site

    Energy Technology Data Exchange (ETDEWEB)

    Sobolik, Steven R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Geotechnology and Engineering Dept.

    2016-03-01

    The Department of Energy, in response to requests from the U.S. Congress, wishes to maintain an up-to-date table documenting the number of available full drawdowns of each of the caverns owned by the Strategic Petroleum Reserve. This information is important for assessing the SPR’s ability to deliver oil to domestic oil companies expeditiously if national or world events dictate a rapid sale and deployment of the oil reserves. What factors go into assessing available drawdowns? The evaluation of drawdown risks require the consideration of several factors regarding cavern and wellbore integrity and stability, including stress states caused by cavern geometry and operations, salt damage caused by dilatant and tensile stresses, the effect on enhanced creep on wellbore integrity, the sympathetic stress effect of operations on neighboring caverns. Based on the work over the past several months, a consensus has been built regarding the assessment of drawdown capabilities and risks for the SPR caverns. This paper draws upon the recently West Hackberry model upgrade and analyses to reevaluate and update the available drawdowns for each of those caverns. Similar papers for the Bryan Mound, Big Hill, and Bayou Choctaw papers will be developed as the upgrades to those analyses are completed. The rationale and documentation of the methodology is described in the remainder of this report, as are the updated estimates of available drawdowns for the West Hackberry caverns.

  3. THE IMPLEMENTATION OF EFFICIENT TRADE MATRIX AND GOLD RESERVE REQUIREMENT FOR COMMODITY TRADE AMONG ASEAN COUNTRIES

    Directory of Open Access Journals (Sweden)

    nurul anisak

    2017-06-01

    Full Text Available Objective - This study attempts to implement the efficient trade matrix among five selected ASEAN countries and its settlement by the gold reserve requirements through Multi-Bilateral Payments Arrangement (MBPA.Methods – The study is a qualitative research with analytic description. The purpose of this qualitative-descriptive study is to simulate the implementation of gold in the Multi-Bilateral Payment Arrangement among ASEAN countries using the current trade data.Results – This paper argues that the Southeast Asian countries can solve the problem through their internal coordination, particularly in terms of trade. One of the efforts is to reduce even eliminate the market risk by using the efficient payment arrangement.Conclusions – The study implied that the quantity amount of gold required to settle the trade balance will be reduced from the early gross payment. However, the ASEAN countries need to strengthen the cooperation among them through maximizing the trade relationship.

  4. The Impact of the Required Reserve on the Monetary Multiplication in the Republic of Macedonias

    Directory of Open Access Journals (Sweden)

    Aleksandar Dejanovski

    2014-11-01

    Full Text Available One of the primary and most important tasks of any central bank is conducting monetary policy in the state. In Macedonia the only central and issuing bank is the National Bank of Macedonia, which is responsible for the monetary and financial stability in the country, while performing important functions, without which the overall economic and financial system could not exist. In exercising its functions, the National Bank of Macedonia uses a set of economic instruments and policies, from which in RM the most efective is the required resserve. This monetary tool is showing the best results in developing countries where the financial markets are not developed and where there is a high concentration of the banking sector (in RM banks occupy a good 98% of total financial institutions. The role of the reserve will be analyzed through the prism of its effects on the process of multiplication the money supply in the country and its contribution to generating or withdrawal of money by the central bank. The main goal of the paper is to research the required reserve, as a monetary instrument, and to qualify its impact on the monetary creation in the Republic of Macedonia. The basic methods, used in this paper are the positive analysis, comparative analysis and deductive approach.

  5. Two-Channel SPR Sensor Combined Application of Polymer- and Vitreous-Clad Optic Fibers

    Directory of Open Access Journals (Sweden)

    Yong Wei

    2017-12-01

    Full Text Available By combining a polymer-clad optic fiber and a vitreous-clad optic fiber, we proposed and fabricated a novel optic fiber surface plasmon resonance (SPR sensor to conduct two-channel sensing at the same detection area. The traditional optic fiber SPR sensor has many disadvantages; for example, removing the cladding requires corrosion, operating it is dangerous, adjusting the dynamic response range is hard, and producing different resonance wavelengths in the sensing area to realize a multi-channel measurement is difficult. Therefore, in this paper, we skillfully used bare fiber grinding technology and reverse symmetry welding technology to remove the cladding in a multi-mode fiber and expose the evanescent field. On the basis of investigating the effect of the grinding angle on the dynamic range change of the SPR resonance valley wavelength and sensitivity, we combined polymer-clad fiber and vitreous-clad fiber by a smart design structure to realize at a single point a two-channel measurement fiber SPR sensor. In this paper, we obtained a beautiful spectral curve from a multi-mode fiber two-channel SPR sensor. In the detection range of the refractive rate between 1.333 RIU and 1.385 RIU, the resonance valley wavelength of channel Ⅰ shifted from 622 nm to 724 nm with a mean average sensitivity of 1961 nm/RIU and the resonance valley wavelength of channel Ⅱ shifted from 741 nm to 976 nm with a mean average sensitivity of 4519 nm/RIU.

  6. An organizational survey of the Strategic Petroleum Reserve

    Energy Technology Data Exchange (ETDEWEB)

    Shurberg, D.A.; Haber, S.B.

    1992-01-01

    At the request of the management of the Strategic Petroleum Reserve (SPR), an Organizational Survey (OS), identical to the one that has been used prior to Tiger Team Assessments at other Department Energy facilities, was administered at SPR independent of a Tiger Team Assessment. The OS measured employees` opinions on subjects such as organizational culture, communication, commitment, group cohesion, coordination, safety, environmental issues, and job satisfaction. The result of this work was a quantitative measure of these variables at the SPR site. SPR management intends to utilize these results in their self-assessment process in preparation for an upcoming Tiger Team Assessment. This report presents these results and discusses their interpretation.

  7. Strategic Petroleum Reserve Program stewardship report No. 1

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-11-03

    This report is a managerial evaluation of the Strategic Petroleum Reserve (SPR) Program conducted by the SPR program director and project manager. Current capabilities and goals of the program have been assessed resulting in an achievable SPR baseline for performance and measurement of this program. Projections and recommendations are based on available technical, schedule, and cost information, taking into account known influencing factors. The SPR Baseline incorporates current critical factors and deviations from the FY 1980 budget data bases. Data on existing sites, expansion sites, turnkey sites, program cost, and withdrawal are included.

  8. Effects of the Interest Rate and Reserve Requirement Ratio on Bank Risk in China: A Panel Smooth Transition Regression Approach

    Directory of Open Access Journals (Sweden)

    Zhongyuan Geng

    2015-01-01

    Full Text Available This paper applies the Panel Smooth Transition Regression (PSTR model to simulate the effects of the interest rate and reserve requirement ratio on bank risk in China. The results reveal the nonlinearity embedded in the interest rate, reserve requirement ratio, and bank risk nexus. Both the interest rate and reserve requirement ratio exert a positive impact on bank risk for the low regime and a negative impact for the high regime. The interest rate performs a significant effect while the reserve requirement ratio shows an insignificant effect on bank risk on a statistical basis for both the high and low regimes.

  9. Arabidopsis plastidial folylpolyglutamate synthetase is required for seed reserve accumulation and seedling establishment in darkness.

    Directory of Open Access Journals (Sweden)

    Hongyan Meng

    Full Text Available Interactions among metabolic pathways are important in plant biology. At present, not much is known about how folate metabolism affects other metabolic pathways in plants. Here we report a T-DNA insertion mutant (atdfb-3 of the plastidial folylpolyglutamate synthetase gene (AtDFB was defective in seed reserves and skotomorphogenesis. Lower carbon (C and higher nitrogen (N content in the mutant seeds than that of the wild type were indicative of an altered C and N partitioning capacity. Higher levels of organic acids and sugars were detected in the mutant seeds compared with the wild type. Further analysis revealed that atdfb-3 seeds contained less total amino acids and individual Asn and Glu as well as NO3-. These results indicate significant changes in seed storage in the mutant. Defects in hypocotyl elongation were observed in atdfb-3 in darkness under sufficient NO3- conditions, and further enhanced under NO3- limited conditions. The strong expression of AtDFB in cotyledons and hypocotyl during early developmental stage was consistent with the mutant sensitivity to limited NO3- during a narrow developmental window. Exogenous 5-formyl-tetrahydrofolate completely restored the hypocotyl length in atdfb-3 seedlings with NO3- as the sole N source. Further study demonstrated that folate profiling and N metabolism were perturbed in atdfb-3 etiolated seedlings. The activity of enzymes involved in N reduction and assimilation was altered in atdfb-3. Taken together, these results indicate that AtDFB is required for seed reserves, hypocotyl elongation and N metabolism in darkness, providing novel insights into potential associations of folate metabolism with seed reserve accumulation, N metabolism and hypocotyl development in Arabidopsis.

  10. A new spinning reserve requirement forecast method for deregulated electricity markets

    International Nuclear Information System (INIS)

    Amjady, Nima; Keynia, Farshid

    2010-01-01

    Ancillary services are necessary for maintaining the security and reliability of power systems and constitute an important part of trade in competitive electricity markets. Spinning Reserve (SR) is one of the most important ancillary services for saving power system stability and integrity in response to contingencies and disturbances that continuously occur in the power systems. Hence, an accurate day-ahead forecast of SR requirement helps the Independent System Operator (ISO) to conduct a reliable and economic operation of the power system. However, SR signal has complex, non-stationary and volatile behavior along the time domain and depends greatly on system load. In this paper, a new hybrid forecast engine is proposed for SR requirement prediction. The proposed forecast engine has an iterative training mechanism composed of Levenberg-Marquadt (LM) learning algorithm and Real Coded Genetic Algorithm (RCGA), implemented on the Multi-Layer Perceptron (MLP) neural network. The proposed forecast methodology is examined by means of real data of Pennsylvania-New Jersey-Maryland (PJM) electricity market and the California ISO (CAISO) controlled grid. The obtained forecast results are presented and compared with those of the other SR forecast methods. (author)

  11. Nano Sensing and Energy Conversion Using Surface Plasmon Resonance (SPR

    Directory of Open Access Journals (Sweden)

    Iltai (Isaac Kim

    2015-07-01

    Full Text Available Nanophotonic technique has been attracting much attention in applications of nano-bio-chemical sensing and energy conversion of solar energy harvesting and enhanced energy transfer. One approach for nano-bio-chemical sensing is surface plasmon resonance (SPR imaging, which can detect the material properties, such as density, ion concentration, temperature, and effective refractive index in high sensitivity, label-free, and real-time under ambient conditions. Recent study shows that SPR can successfully detect the concentration variation of nanofluids during evaporation-induced self-assembly process. Spoof surface plasmon resonance based on multilayer metallo-dielectric hyperbolic metamaterials demonstrate SPR dispersion control, which can be combined with SPR imaging, to characterize high refractive index materials because of its exotic optical properties. Furthermore, nano-biophotonics could enable innovative energy conversion such as the increase of absorption and emission efficiency and the perfect absorption. Localized SPR using metal nanoparticles show highly enhanced absorption in solar energy harvesting. Three-dimensional hyperbolic metamaterial cavity nanostructure shows enhanced spontaneous emission. Recently ultrathin film perfect absorber is demonstrated with the film thickness is as low as ~1/50th of the operating wavelength using epsilon-near-zero (ENZ phenomena at the wavelength close to SPR. It is expected to provide a breakthrough in sensing and energy conversion applications using the exotic optical properties based on the nanophotonic technique.

  12. Tiger Team Assessment of the Strategic Petroleum Reserve

    International Nuclear Information System (INIS)

    1992-04-01

    This report documents the Tiger Team Assessment of the Strategic Petroleum Reserves (SPR) located in Louisiana and Texas, which consists of a project management office in New Orleans, a marine terminal located on the Mississippi River in Louisiana, and five crude oil storage sites in Louisiana and Texas. SPR is operated by Boeing Petroleum Services, Inc. for the US Department of Energy (DOE). DOE's Office of Fossil Energy (FE) is the responsible program organization and the Department of Energy Strategic Petroleum Reserve Project Management Office (SPRPMO) in Louisiana provides local oversight. The Tiger Team Assessment was conducted from March 9 to April 10, 1992, under the auspices of DOE's Office of Special Projects (OSP) under the Office of Environment, Safety and Health (EH). The assessment was comprehensive, encompassing environmental, safety, and health (ES ampersand H), and quality assurance (QA) disciplines; site remediation; facilities management; and waste management operations. Compliance with applicable Federal, States of Louisiana and Texas, and local regulations; applicable DOE Orders; best management practices; and internal SPR requirements was assessed. In addition, an evaluation of the adequacy and effectiveness of SPRPMO and BPS management of the ES ampersand H/QA and self-assessment programs was conducted. 6 fig., 22 tab

  13. Comparison of different photoresist buffer layers in SPR sensors based on D-shaped POF and gold film

    Science.gov (United States)

    Cennamo, Nunzio; Pesavento, Maria; De Maria, Letizia; Galatus, Ramona; Mattiello, Francesco; Zeni, Luigi

    2017-04-01

    A comparative analysis of two optical fiber sensing platforms is presented. The sensors are based on surface plasmon resonance (SPR) in a D-shaped plastic optical fiber (POF) with a photoresist buffer layer between the exposed POF core and the thin gold film. We show how the sensor's performances change when the photoresist layer changes. The photoresist layers proposed in this analysis are SU-8 3005 and S1813. The experimental results are congruent with the numerical studies and it is instrumental for chemical and bio-chemical applications. Usually, the photoresist layer is required in order to increase the performance of the SPR-POF sensor.

  14. Analysis of cavern stability at the West Hackberry SPR site.

    Energy Technology Data Exchange (ETDEWEB)

    Ehgartner, Brian L.; Sobolik, Steven Ronald

    2009-05-01

    This report presents computational analyses that simulate the structural response of caverns at the Strategic Petroleum Reserve (SPR) West Hackberry site. The cavern field comprises 22 caverns. Five caverns (6, 7, 8, 9, 11) were acquired from industry and have unusual shapes and a history dating back to 1946. The other 17 caverns (101-117) were leached according to SPR standards in the mid-1980s and have tall cylindrical shapes. The history of the caverns and their shapes are simulated in a three-dimensional geomechanics model of the site that predicts deformations, strains, and stresses. Future leaching scenarios corresponding to oil drawdowns using fresh water are also simulated by increasing the volume of the caverns. Cavern pressures are varied in the model to capture operational practices in the field. The results of the finite element model are interpreted to provide information on the current and future status of subsidence, well integrity, and cavern stability. The most significant results in this report are relevant to Cavern 6. The cavern is shaped like a bowl with a large ceiling span and is in close proximity to Cavern 9. The analyses predict tensile stresses at the edge of the ceiling during repressuization of Cavern 6 following workover conditions. During a workover the cavern is at low pressure to service a well. The wellhead pressures are atmospheric. When the workover is complete, the cavern is repressurized. The resulting elastic stresses are sufficient to cause tension around the edge of the large ceiling span. With time, these stresses relax to a compressive state because of salt creep. However, the potential for salt fracture and propagation exists, particularly towards Cavern 9. With only 200 ft of salt between the caverns, the operational consequences must be examined if the two caverns become connected. A critical time may be during a workover of Cavern 9 in part because of the operational vulnerabilities, but also because dilatant damage is

  15. Requirement for Naval Reserve Component Units Not Assigned to Support Regional Contingencies

    National Research Council Canada - National Science Library

    Gimble, Thomas

    1996-01-01

    Our primary objective was to determine whether a valid need exists for Naval Reserve units and non-unit Reserve personnel who are not assigned to meet the needs of anticipated regional contingencies...

  16. Floating chip mounting system driven by repulsive force of permanent magnets for multiple on-site SPR immunoassay measurements.

    Science.gov (United States)

    Horiuchi, Tsutomu; Tobita, Tatsuya; Miura, Toru; Iwasaki, Yuzuru; Seyama, Michiko; Inoue, Suzuyo; Takahashi, Jun-ichi; Haga, Tsuneyuki; Tamechika, Emi

    2012-10-17

    We have developed a measurement chip installation/removal mechanism for a surface plasmon resonance (SPR) immunoassay analysis instrument designed for frequent testing, which requires a rapid and easy technique for changing chips. The key components of the mechanism are refractive index matching gel coated on the rear of the SPR chip and a float that presses the chip down. The refractive index matching gel made it possible to optically couple the chip and the prism of the SPR instrument easily via elastic deformation with no air bubbles. The float has an autonomous attitude control function that keeps the chip parallel in relation to the SPR instrument by employing the repulsive force of permanent magnets between the float and a float guide located in the SPR instrument. This function is realized by balancing the upward elastic force of the gel and the downward force of the float, which experiences a leveling force from the float guide. This system makes it possible to start an SPR measurement immediately after chip installation and to remove the chip immediately after the measurement with a simple and easy method that does not require any fine adjustment. Our sensor chip, which we installed using this mounting system, successfully performed an immunoassay measurement on a model antigen (spiked human-IgG) in a model real sample (non-homogenized milk) that included many kinds of interfering foreign substances without any sample pre-treatment. The ease of the chip installation/removal operation and simple measurement procedure are suitable for frequent on-site agricultural, environmental and medical testing.

  17. Floating Chip Mounting System Driven by Repulsive Force of Permanent Magnets for Multiple On-Site SPR Immunoassay Measurements

    Directory of Open Access Journals (Sweden)

    Emi Tamechika

    2012-10-01

    Full Text Available We have developed a measurement chip installation/removal mechanism for a surface plasmon resonance (SPR immunoassay analysis instrument designed for frequent testing, which requires a rapid and easy technique for changing chips. The key components of the mechanism are refractive index matching gel coated on the rear of the SPR chip and a float that presses the chip down. The refractive index matching gel made it possible to optically couple the chip and the prism of the SPR instrument easily via elastic deformation with no air bubbles. The float has an autonomous attitude control function that keeps the chip parallel in relation to the SPR instrument by employing the repulsive force of permanent magnets between the float and a float guide located in the SPR instrument. This function is realized by balancing the upward elastic force of the gel and the downward force of the float, which experiences a leveling force from the float guide. This system makes it possible to start an SPR measurement immediately after chip installation and to remove the chip immediately after the measurement with a simple and easy method that does not require any fine adjustment. Our sensor chip, which we installed using this mounting system, successfully performed an immunoassay measurement on a model antigen (spiked human-IgG in a model real sample (non-homogenized milk that included many kinds of interfering foreign substances without any sample pre-treatment. The ease of the chip installation/removal operation and simple measurement procedure are suitable for frequent on-site agricultural, environmental and medical testing.

  18. Strategic Petroleum Reserve Site Environmental Report for calendar year 1994

    International Nuclear Information System (INIS)

    1995-01-01

    The purpose of this Site Environmental Report (SER) is to characterize site environmental management performance, confirm compliance with environmental standards and requirements, and highlight significant programs and efforts. The SER, provided annually in accordance with Department of Energy DOE Order 5400.1, serves the public by summarizing monitoring data collected to assess how the Strategic Petroleum Reserve (SPR) impacts the environment. This report (SER) provides a balanced synopsis of non-radiological monitoring and regulatory compliance data and affirms that the SPR has been operating within acceptable regulatory limits. Included in this report is a description of each site's environment, an overview of the SPR environmental program, and a recapitulation of special environmental activities and events associated with each SPR site during 1994. Two of these highlights include decommissioning of the Weeks Island facility (disposition of 73 million barrels of crude oil inventory) as well as the degasification of up to 144 million barrels of crude oil inventory at the Bayou Choctaw, Big Hill, Bryan Mound, and West Hackberry facilities. The decision to decommission the Weeks Island facility is a result of diminishing mine integrity from ground water intrusion. Degasifying the crude oil is required to reduce potentially harmful emissions that would occur during oil movements. With regard to still another major environmental action, 43 of the original 84 environmental findings from the 1992 DOE Tiger Team Assessment were closed by the end of 1994. Spills to the environment, another major topic, indicates a positive trend. Total volume of oil spilled in 1994 was only 39 barrels, down from 232 barrels in 1993, and the total volume of brine spilled was only 90 barrels, down from 370 barrels in 1993. The longer term trend for oil and brine spills has declined substantially from 27 in 1990 down to nine in 1994

  19. Strategic Petroleum Reserve Site Environmental Report for calendar year 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-05-31

    The purpose of this Site Environmental Report (SER) is to characterize site environmental management performance, confirm compliance with environmental standards and requirements, and highlight significant programs and efforts. The SER, provided annually in accordance with Department of Energy DOE Order 5400.1, serves the public by summarizing monitoring data collected to assess how the Strategic Petroleum Reserve (SPR) impacts the environment. This report (SER) provides a balanced synopsis of non-radiological monitoring and regulatory compliance data and affirms that the SPR has been operating within acceptable regulatory limits. Included in this report is a description of each site`s environment, an overview of the SPR environmental program, and a recapitulation of special environmental activities and events associated with each SPR site during 1994. Two of these highlights include decommissioning of the Weeks Island facility (disposition of 73 million barrels of crude oil inventory) as well as the degasification of up to 144 million barrels of crude oil inventory at the Bayou Choctaw, Big Hill, Bryan Mound, and West Hackberry facilities. The decision to decommission the Weeks Island facility is a result of diminishing mine integrity from ground water intrusion. Degasifying the crude oil is required to reduce potentially harmful emissions that would occur during oil movements. With regard to still another major environmental action, 43 of the original 84 environmental findings from the 1992 DOE Tiger Team Assessment were closed by the end of 1994. Spills to the environment, another major topic, indicates a positive trend. Total volume of oil spilled in 1994 was only 39 barrels, down from 232 barrels in 1993, and the total volume of brine spilled was only 90 barrels, down from 370 barrels in 1993. The longer term trend for oil and brine spills has declined substantially from 27 in 1990 down to nine in 1994.

  20. The behavior of crude oil spot and futures prices around OPEC and SPR announcements. An event study perspective

    International Nuclear Information System (INIS)

    Demirer, Riza; Kutan, Ali M.

    2010-01-01

    This paper examines the informational efficiency of crude oil spot and futures markets with respect to OPEC conference and U.S. Strategic Petroleum Reserve (SPR) announcements. We employ the event study methodology to examine the abnormal returns in crude oil spot and futures markets around OPEC conference and SPR announcement dates between 1983 and 2008. Our findings regarding OPEC announcements indicate an asymmetry in that only OPEC production cut announcements yield a statistically significant impact with the impact diminishing for longer maturities. We also find that the persistence of returns following OPEC production cut announcements creates substantial excess returns to investors who take long positions on the day following the end of OPEC conferences. In the case of SPR announcements, we find that the government's use of this program initiates a short-run market reaction following the announcement date. Furthermore, our tests of cumulative abnormal returns suggest that the market reacts efficiently to SPR announcements providing support for the use of the strategic reserves as a tool to stabilize the oil market. Our findings have significant policy implications for investors and are useful in designing effective energy policy strategies. (author)

  1. Determining reserve requirements in DK1 area of Nord Pool using a probabilistic approach

    DEFF Research Database (Denmark)

    Saez Gallego, Javier; Morales González, Juan Miguel; Madsen, Henrik

    2014-01-01

    area of Nord Pool, where reserves are scheduled prior to the closure of the day-ahead market. The risk of the solution under the resulting reserve schedule is controlled by two measures: the LOLP (Loss-of-Load Probability) and the CVaR (Conditional Value at Risk). Results show that during the case...

  2. A sensitive SPR biosensor based on hollow gold nanospheres and improved sandwich assay with PDA-Ag@Fe3O4/rGO.

    Science.gov (United States)

    Li, Shuo; Wu, Qiong; Ma, Pinyi; Zhang, Yue; Song, Daqian; Wang, Xinghua; Sun, Ying

    2018-04-01

    A novel surface plasmon resonance (SPR) biosensor based on hollow gold nanospheres (HGNPs) and an improved sandwich assay was developed to detect rabbit IgG. The electromagnetic coupling between the HGNPs and Au film, and the notable plasmonic fields spread over the inner and outer surfaces of HGNPs, led to the considerable amplification of the SPR signal. Polydopamine-Ag@Fe 3 O 4 /reduced graphene oxide (PDA-Ag@Fe 3 O 4 /rGO) was introduced to bind detection antibody (Ab 2 ) to form the improved sandwich structure. Ag nanoparticles were excited to produce SPR and their hot electrons were doped on graphene thin films, which amplified the response of biomolecules. Magnetic nanoparticles (Fe 3 O 4 ) simplified the collection of Ab 2 -PDA-Ag@Fe 3 O 4 /rGO. An external layer of polydopamine (PDA) permitted the efficient immobilization of Ab 2 without activation via abundant functional groups and protected the nanoparticles from etching or agglomeration. In addition, because of its large mass, Ab 2 -PDA-Ag@Fe 3 O 4 /rGO also played a key role in the further amplification of the SPR response signals. This novel SPR biosensor exhibited an effective response to the rabbit IgG at the different concentrations ranging from 0.019 to 40.00μgmL -1 . This value is 132 times lower than that observed for a traditional SPR biosensor based on Au-3-mercaptopropionic acid and 8 times lower than that obtained from an Ab 2 sandwich assay, which indicates that the SPR sensor has high sensitivity. In addition, the designed biosensor showed satisfactory recoveries to detect the rabbit IgG spiked in serum samples. Therefore, the novel SPR biosensor with high sensitivity and acceptable recovery has potential for practical applications. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. SPR Hydrostatic Column Model Verification and Validation.

    Energy Technology Data Exchange (ETDEWEB)

    Bettin, Giorgia [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lord, David [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Rudeen, David Keith [Gram, Inc. Albuquerque, NM (United States)

    2015-10-01

    A Hydrostatic Column Model (HCM) was developed to help differentiate between normal "tight" well behavior and small-leak behavior under nitrogen for testing the pressure integrity of crude oil storage wells at the U.S. Strategic Petroleum Reserve. This effort was motivated by steady, yet distinct, pressure behavior of a series of Big Hill caverns that have been placed under nitrogen for extended period of time. This report describes the HCM model, its functional requirements, the model structure and the verification and validation process. Different modes of operation are also described, which illustrate how the software can be used to model extended nitrogen monitoring and Mechanical Integrity Tests by predicting wellhead pressures along with nitrogen interface movements. Model verification has shown that the program runs correctly and it is implemented as intended. The cavern BH101 long term nitrogen test was used to validate the model which showed very good agreement with measured data. This supports the claim that the model is, in fact, capturing the relevant physical phenomena and can be used to make accurate predictions of both wellhead pressure and interface movements.

  4. Issues related to SPR joints subjected to fatigue loads

    Science.gov (United States)

    De Luca, A.; Senatore, F.; Greco, A.

    2016-05-01

    SPR joints will represent an alternative solution to spot welding in automotive field. However, their fatigue behavior shows several critical issues. After a brief introduction of this new solution, different crack modes are described, emphasizing the parameters that characterize them, i.e. the applied loads, the geometry of the joint and other phenomenon as fretting, vibration and corrosion.

  5. Experimental tests on commercial Sweet Product Residue (SPR) as a suitable feed for anaerobic bioenergy (H2+CH4) production.

    Science.gov (United States)

    Malavè, Andrea C Luongo; Fino, Debora; Gómez Camacho, Carlos E; Ruggeri, Bernardo

    2018-01-01

    Food stores can find themselves in the position of having to dispose of different types of products, such as snacks, confectionery, prepackaged food, drinks and others, Sweet Product Residue (SPR), which presents a great opportunity to produce energy through Anaerobic Digestion (AD), due to its high sugar, carbohidrate and fat contents. In order to valorise SPR, this paper takes into consideration the all necessary treatments; owing the fact that the refuses are constitute by an organic part and packaging (plastic, paper and their combinations), a pretreatment able to remove the latter is necessary. SPR refuse was initially subjected to novel pretreatment approach: extrusion at 200atm to remove the packaging, and a Basic Pre-treatment (BP) then tested through a Two-Stage AD (TSAD) process, for H 2 and CH 4 productions. The experimental results were analysed considering three parameters: Efficiency (ξ), which takes into account the quantity of the energy produced as hydrogen plus methane that the bioreaction is able to extract; Efficacy (η), which takes into account the efficiency of the actual test, compared with that obtained from a reference test carried out with glucose; Energy Sustainability Index (ESI), which takes into account the total amount of energy produced as H 2 plus CH 4 , and the amount of energy consumed to pre-treat the refuse. The effectiveness of the extrusion process in removing the packaging was very high: about 80% of the organic part present in the SPR was recovered. The obtained results have pointed out that SPR is suitable for energy valorization process: ξ=50%, η=0.67 and ESI=24.4, without the need of basic pre-treatment. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Investigation of LPG-SPR sensors using the finite element method and eigenmode expansion method.

    Science.gov (United States)

    He, Yue Jing

    2013-06-17

    As compared to the well-known traditional couple-mode theory, in this study, we proposed a visual, graphical, and simple numerical simulation method for long-period fiber-grating surface-plasmon-resonance (LPG-SPR) sensors. This method combines the finite element method and the eigenmode expansion method. The finite element method was used to solve for the guided modes in fiber structures, including the surface plasmon wave. The eigenmode expansion method was used to calculate the power transfer phenomenon of the guided modes in the fiber structure. This study provides a detailed explanation of the key reasons why the periodic structure of long-period fiber-grating (LPG) can achieve significantly superior results for our method compared to those obtained using other numerical methods, such as the finite-difference time-domain and beam propagation methods. All existing numerical simulation methods focus on large-sized periodic components; only the method established in this study has 3D design and analysis capabilities. In addition, unlike the offset phenomenon of the design wavelength λ(D) and the maximum transmission wavelength λ(max) of the traditional coupled-mode theory, the method established in this study has rapid scanning LPG period capabilities. Therefore, during the initial component design process, only the operating wavelength must be set to ensure that the maximum transmission wavelength of the final product is accurate to the original setup, for example, λ = 1550 nm. We verified that the LPG-SPR sensor designed in this study provides a resolution of ~-45 dB and a sensitivity of ~27000 nm/RIU (refractive index unit). The objective of this study was to use the combination of these two numerical simulation methods in conjunction with a rigorous, simple, and complete design process to provide a graphical and simplistic simulation technique that reduces the learning time and professional threshold required for research and applications of LPG-SPR

  7. Mentha spicata L. infusions as sources of antioxidant phenolic compounds: emerging reserve lots with special harvest requirements.

    Science.gov (United States)

    Rita, Ingride; Pereira, Carla; Barros, Lillian; Santos-Buelga, Celestino; Ferreira, Isabel C F R

    2016-10-12

    Mentha spicata L., commonly known as spearmint, is widely used in both fresh and dry forms, for infusion preparation or in European and Indian cuisines. Recently, with the evolution of the tea market, several novel products with added value are emerging, and the standard lots have evolved to reserve lots, with special harvest requirements that confer them with enhanced organoleptic and sensorial characteristics. The apical leaves of these batches are collected in specific conditions having, then, a different chemical profile. In the present study, standard and reserve lots of M. spicata were assessed in terms of the antioxidants present in infusions prepared from the different lots. The reserve lots presented the highest concentration in all the compounds identified in relation to the standard lots, with 326 and 188 μg mL -1 of total phenolic compounds, respectively. Both types of samples presented rosmarinic acid as the most abundant phenolic compound, at concentrations of 169 and 101 μg mL -1 for reserve and standard lots, respectively. The antioxidant activity was higher in the reserve lots which had the highest total phenolic compounds content, with EC 50 values ranging from 152 to 336 μg mL -1 . The obtained results provide scientific information that may allow the consumer to make a conscientious choice.

  8. Antibody characterization and immunoassays for palytoxin using an SPR biosensor.

    Science.gov (United States)

    Yakes, Betsy Jean; DeGrasse, Stacey L; Poli, Mark; Deeds, Jonathan R

    2011-07-01

    Palytoxin (PLTX), a polyether marine toxin originally isolated from the zoanthid Palythoa toxica, is one of the most toxic non-protein substances known. Fatal poisonings have been linked to ingestion of PLTX-contaminated seafood, and effects in humans have been associated with dermal and inhalational exposure to PLTX containing organisms and waters. Additionally, PLTX co-occurrence with other well-characterized seafood toxins (e.g., ciguatoxins, saxitoxins, tetrodotoxin) has hindered direct associations of PLTX to seafood-borne illnesses. There are currently no validated methods for the quantitative detection of PLTX(s). As such, a well-characterized, robust, specific analytical technique is needed for the detection of PLTX(s) in source organisms, surrounding waters, and clinical samples. Surface plasmon resonance (SPR) biosensors are ideally suited for antibody characterization and quantitative immunoassay detection. Herein, we describe a newly developed SPR assay for PLTX. An anti-mouse substrate was used to characterize the kinetic values for a previously developed monoclonal anti-PLTX. The characterized antibody was then incorporated into a sensitive, rapid, and selective PLTX assay. Buffer type, flow rate, analyte-binding time, and regeneration conditions were optimized for the antibody-PLTX system. Cross-reactivity to potentially co-occurring seafood toxins was also evaluated. We show that this optimized assay is capable of measuring low- to sub-ng/mL PLTX levels in buffer and two seafood matrices (grouper and clam). Preliminary results indicate that this SPR biosensor assay allows for (1) rapid characterization of antibodies and (2) rapid, sensitive PLTX concentration determination in seafood matrices. Method development information contained herein may be broadly applied to future PLTX detection and/or antibody characterization efforts.

  9. SPR imaging combined with cyclic voltammetry for the detection of neural activity

    Directory of Open Access Journals (Sweden)

    Hui Li

    2014-03-01

    Full Text Available Surface plasmon resonance (SPR detects changes in refractive index at a metal-dielectric interface. In this study, SPR imaging (SPRi combined with cyclic voltammetry (CV was applied to detect neural activity in isolated bullfrog sciatic nerves. The neural activities induced by chemical and electrical stimulation led to an SPR response, and the activities were recorded in real time. The activities of different parts of the sciatic nerve were recorded and compared. The results demonstrated that SPR imaging combined with CV is a powerful tool for the investigation of neural activity.

  10. Phase detection model and method for SPR effect modulated by metallic thickness

    Science.gov (United States)

    Liu, Qinggang; Li, Yang; Qin, Zirui; Yue, Chong

    2017-06-01

    A mathematic model based on surface plasmon resonance (SPR) effect is presented to measure the nano metallic film thickness with the coupling device of Kretschmann configuration composed of K9 prism-gold film-air. Four modulation modes of SPR method, such as intensity, phase, wavelength and angle, are numerically analyzed. Their detection principles, the measurement range and sensitivity of different modulation type sensors are discussed. The simulation results show that the SPR intensity detection method has the highest measurement range and the SPR phase detection method has the highest sensitivity. In practical applications, not only the measurement range and sensitivity, but the optical signal processing mode, experiment devices, the complexity of the algorithm and cost factors should be considered to research and develop the appropriate thin metallic film's thickness measurement SPR sensor with higher sensitivity and stability.

  11. The U.S. Strategic Petroleum Reserve: Needed Changes to Counter Today's Threats to Energy Security

    National Research Council Canada - National Science Library

    Peck, Jr, Bruce L

    2006-01-01

    The Strategic Petroleum Reserve (SPR) of the United States is critical to its national security because of the nation's reliance on oil and refined petroleum products as the cornerstone of its economic and military power...

  12. Quick and sensitive SPR detection of prion disease-associated isoform (PrPSc) based on its self-assembling behavior on bare gold film and specific interactions with aptamer-graphene oxide (AGO).

    Science.gov (United States)

    Lou, Zhichao; Wan, Jinfeng; Zhang, Xiaohong; Zhang, Haiqian; Zhou, Xiaoyan; Cheng, Su; Gu, Ning

    2017-09-01

    Herein, we constructed a novel sandwich surface plasmon resonance (SPR) detection assay for sensitive prion disease-associated isoform (PrP Sc ) detection, utilizing bare gold film and apatamer-graphene oxide (AGO). Due to the self-assembling behavior of PrP Sc on gold surface, the non-modified gold surface can be directly used as sensing surface for the quick detection, for the purpose to avoid the interference from the traditional, complex and changeable probe-modified sensing surface. And due to the highly specific affinity of AGO towards PrP Sc , the sandwich type SPR sensor exhibits excellent analytical performance towards the discrimination and quantitation of PrP Sc . A good linear relationship was obtained between SPR responses and the logarithm of PrP Sc concentrations over a range of 0.001-1ng/mL. The detection sensitivity for PrP Sc was improved by ∼156 orders of AGO compared with SPR direct detection format. Besides, morphological changes of the sensing film surfaces were investigated by high resolution AFM imaging, confirming the capture of PrP Sc molecules and their further specific recognition by AGO. The specificity of the present biosensor was also investigated by PrP C and other regents as controls. By compared with other reported methods, the AGO enhanced sandwich SPR assay was confirmed to be efficient, sensitive, and with wide working range. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Reform of reserve requirements for nuclear decommissioning, dismantling and disposal; Reform der Atomrueckstellungen fuer Stilllegung/Rueckbau und Entsorgung

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, Bettina [Forum Oekologisch-Soziale Marktwirtschaft e.V. (FOeS), Berlin (Germany); Kuechler, Swantje; Wronski, Rupert [Forum Oekologisch-Soziale Marktwirtschaft e.V. (FOeS), Berlin (Germany). Bereich Energiepolitik

    2015-07-15

    This article reports on the ongoing intense discussion as to whether the financial reserves of nuclear power plant operators are sufficient. It starts out with an overview of the current scientific and political debate. This is followed by a brief analysis of nuclear financial reserves in 2014 and preceding years. The authors then present the reform concept of the Forum Oekologisch-Soziale Marktwirtschaft (FOes) and go on to compare it with concepts from the political realm.

  14. Mobilní aplikace pro správu DNS

    OpenAIRE

    Galajda, Denis

    2016-01-01

    Táto bakalárska práca sa zaoberá možnosťami a špecifikami tvorby vlastnej mobilnej aplikácie pre správu DNS na systém Android. Cieľom je vytvorenie prehľadnej aplikácie, jednoduchej na ovládanie, ktorá používateľovi umožní manažovať zóny a záznamy DNS doménového serveru BIND9. Tento problém rieši manipuláciou zónových súborov cez SSH pripojenie, ktorá je ovládaná moderným používateľským rozhraním. Výsledný program umožňuje používateľom pohodlne spravovať DNS server zo svojho chytrého telefónu...

  15. Recent operational history of the new Sandia Pulsed Reactor III (SPR III)

    International Nuclear Information System (INIS)

    Schmidt, T.R.; Estes, B.F.; Reuscher, J.A.

    1977-01-01

    The Sandia Pulsed Reactor III (SPR III) is a fast-pulse research reactor which was designed and built at Sandia Laboratories and achieved criticality in August 1975. The reactor is now characterized and is in an operational configuration. The core consists of 18 fuel plates (258 kg fuel mass) of fully enriched uranium alloyed with 10 wt.% molybdenum. It is arranged in an annular configuration with an inside diameter of 17.78 cm, an outside diameter of 29.72 cm, and a height of 35.9 cm. The reactor core uses reflectors of copper and aluminum for control and an external bolting arrangement to secure the fuel plates. SPR III and SPR II are operated on an interchangeable basis using the same facility and control system. As of June 1977, SPR III has had over 240 operations with core temperatures up to 541 0 C

  16. Interaction between a cationic porphyrin and ctDNA investigated by SPR, CV and UV-vis spectroscopy.

    Science.gov (United States)

    Xu, Zi-Qiang; Zhou, Bo; Jiang, Feng-Lei; Dai, Jie; Liu, Yi

    2013-10-01

    The interaction between ctDNA and a cationic porphyrin was studied in this work. The binding process was monitored by surface plasmon resonance (SPR) spectroscopy in detail. The association, dissociation rate constants and the binding constants calculated by global analysis were 2.4×10(2)±26.4M(-1)s(-1), 0.011±0.0000056s(-1) and 2.18×10(4)M(-1), respectively. And the results were confirmed by cyclic voltammetry and UV-vis absorption spectroscopy. The binding constants obtained from cyclic voltammetry and UV-vis absorption spectroscopy were 8.28×10(4)M(-1) and 6.73×10(4)M(-1) at 298K, respectively. The covalent immobilization methodology of ctDNA onto gold surface modified with three different compounds was also investigated by SPR. These compounds all contain sulfydryl but with different terminated functional groups. The results indicated that the 11-MUA (HS(CH2)10COOH)-modified gold film is more suitable for studying the DNA-drug interaction. Copyright © 2013 Elsevier B.V. All rights reserved.

  17. Enhancement in sensitivity of graphene-based zinc oxide assisted bimetallic surface plasmon resonance (SPR) biosensor

    Science.gov (United States)

    Kumar, Rajeev; Kushwaha, Angad S.; Srivastava, Monika; Mishra, H.; Srivastava, S. K.

    2018-03-01

    In the present communication, a highly sensitive surface plasmon resonance (SPR) biosensor with Kretschmann configuration having alternate layers, prism/zinc oxide/silver/gold/graphene/biomolecules (ss-DNA) is presented. The optimization of the proposed configuration has been accomplished by keeping the constant thickness of zinc oxide (32 nm), silver (32 nm), graphene (0.34 nm) layer and biomolecules (100 nm) for different values of gold layer thickness (1, 3 and 5 nm). The sensitivity of the proposed SPR biosensor has been demonstrated for a number of design parameters such as gold layer thickness, number of graphene layer, refractive index of biomolecules and the thickness of biomolecules layer. SPR biosensor with optimized geometry has greater sensitivity (66 deg/RIU) than the conventional (52 deg/RIU) as well as other graphene-based (53.2 deg/RIU) SPR biosensor. The effect of zinc oxide layer thickness on the sensitivity of SPR biosensor has also been analysed. From the analysis, it is found that the sensitivity increases significantly by increasing the thickness of zinc oxide layer. It means zinc oxide intermediate layer plays an important role to improve the sensitivity of the biosensor. The sensitivity of SPR biosensor also increases by increasing the number of graphene layer (upto nine layer).

  18. En språkfundert kompetansemodell for planlegging av undervisning

    Directory of Open Access Journals (Sweden)

    Erik Knain

    2016-04-01

    Full Text Available I utdanningsvitenskapelig litteratur er ulike former for ”literacy” et vedvarende fokus både teoretisk og empirisk. I engelskspråklig naturfagdidaktisk litteratur brukes betegnelsen ”scientific literacy”. Jeg skisserer i denne artikkelen et planleggingsverktøy for undervisning som bygger på en eksplisitt teoretisk modell for deltakelse gjennom språk. Modellen er bindeledd mellom et generalisert kompetansebegrep og planlegging av undervisning ved at den knytter sammen de didaktiske spørsmålene hva, hvem, hvordan og hvorfor med en modell for funksjonell deltakelse. Modellen er spesielt relevant for et allmenndannende ”naturfag for alle”, men favner også et naturfag som fokuserer på utdanning av framtidas naturvitere. Artikkelen retter seg mot naturfag i skolen, men modellen bør kunne anvendes også i andre skolefag. Modellen peker mot et situert og transformativt kompetansebegrep.Nøkkelord: naturfag , kompetanse , diskurs , deltakelse, undervisning og læringAbstractVarious forms of literacy have long been the focus of educational discourses, not the least in science education where the term “scientific literacy” has been an enduring concern for decades. In this article I describe a tool for designing teaching based on a theoretical perspective on participation through language. The model connects a general conception of competence with the planning of teaching. To do so it drowe on the didactical questions of “what, who, how and why”. The model is particularly relevant in a “science for all” perspective but also for the educating of future science specialists. Although school science is the primary focus in this article, the model should be applicable to other school subjects as well. The model opens for a situated and transformative notion of competence.Keywords: scientific literacy, discourse, participation, teaching and learning

  19. Fast and sensitive detection of ochratoxin A in red wine by nanoparticle-enhanced SPR.

    Science.gov (United States)

    Karczmarczyk, Aleksandra; Reiner-Rozman, Ciril; Hageneder, Simone; Dubiak-Szepietowska, Monika; Dostálek, Jakub; Feller, Karl-Heinz

    2016-09-21

    Herein, we present a fast and sensitive biosensor for detection of Ochratoxin A (OTA) in a red wine that utilizes gold nanoparticle-enhanced surface plasmon resonance (SPR). By combining an indirect competitive inhibition immunoassay and signal enhancement by secondary antibodies conjugated with gold nanoparticles (AuNPs), highly sensitive detection of low molecular weight compounds (such as OTA) was achieved. The reported biosensor allowed for OTA detection at concentrations as low as 0.75 ng mL(-1) and its limit of detection was improved by more than one order of magnitude to 0.068 ng mL(-1) by applying AuNPs as a signal enhancer. The study investigates the interplay of size of AuNPs and affinity of recognition elements affecting the efficiency of the signal amplification strategy based on AuNP. Furthermore, we observed that the presence of polyphenolic compounds in wine samples strongly interferes with the affinity binding on the surface. To overcome this limitation, a simple pre-treatment of the wine sample with the binding agent poly(vinylpyrrolidone) (PVP) was successfully applied. Copyright © 2016 Elsevier B.V. All rights reserved.

  20. ACR-SPR-STR Practice Parameter for the Performance of Cardiac Positron Emission Tomography - Computed Tomography (PET/CT) Imaging.

    Science.gov (United States)

    Subramaniam, Rathan M; Janowitz, Warren R; Johnson, Geoffrey B; Lodge, Martin A; Parisi, Marguerite T; Ferguson, Mark R; Hellinger, Jeffrey C; Gladish, Gregory W; Gupta, Narainder K

    2017-12-01

    This clinical practice parameter has been developed collaboratively by the American College of Radiology (ACR), the Society for Pediatric Radiology (SPR), and the Society of Thoracic Radiology (STR). This document is intended to act as a guide for physicians performing and interpreting positron emission tomography-computed tomography (PET/CT) of cardiac diseases in adults and children. The primary value of cardiac PET/CT imaging include evaluation of perfusion, function, viability, inflammation, anatomy, and risk stratification for cardiac-related events such as myocardial infarction and death. Optimum utility of cardiac PET/CT is achieved when images are interpreted in conjunction with clinical information and laboratory data. Measurement of myocardial blood flow, coronary flow reserve and detection of balanced ischemia are significant advantages of cardiac PET perfusion studies. Increasingly cardiac PET/CT is used in diagnosis and treatment response assessment for cardiac sarcoidosis.

  1. Deposition of gold nanoparticle films using spray pyrolysis technique: Tunability of SPR band by electric field

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, Neetesh; Komarala, Vamsi K.; Dutta, Viresh [Photovoltaic Laboratory, Centre for Energy Studies, Indian Institute of Technology Delhi, Hauz Khas, New Delhi-110016 (India)

    2012-10-15

    Gold nanoparticle films are prepared using a simple inexpensive spray pyrolysis technique. X-ray as well as TEM diffraction patterns revealed pure cubic structure. The effect of gold nanoparticle concentration on surface plasmon resonance (SPR) band position and bandwidth are investigated for varying spray solution volume. The tunability of SPR band position and bandwidth using an electric field, by applying a voltage (up to 2000 V) to the nozzle, has been demonstrated. The reduced full width at half maximum and blue shift in the SPR band position are observed with {Delta}{lambda}{sub FW} {proportional_to} 55 nm and {Delta}{lambda}{sub P} {proportional_to} 40 nm for the applied voltage of 2 kV. (copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  2. Správce DNS serverů pro projekt FreenetIS

    OpenAIRE

    Raška, David

    2014-01-01

    Cílem této práce je představit alternativní možnost spravování DNS serverů pomocí grafického rozhraní. V práci je implementováno grafické uživatelské rozhraní pro správu DNS serverů, jejich zón a záznamů a napojení DNS serverů na systém pro správu sítě. Jako DNS server je použit software ISC BIND 9 a rozhraní pro správu je implementováno do open-source projektu FreenetIS. The goal of this bachelor's thesis is to introduce an alternative option of DNS servers management using graphical inte...

  3. Ionization of covalent immobilized poly(4-vinylphenol) monolayers measured by ellipsometry, QCM and SPR

    Energy Technology Data Exchange (ETDEWEB)

    Uppalapati, Suji [Department of Chemistry, University of Massachusetts Lowell, 1 University Ave., Lowell, MA 01854 (United States); Kong, Na; Norberg, Oscar [KTH-Royal Institute of Technology, Department of Chemistry, Teknikringen 30, S-10044 Stockholm (Sweden); Ramström, Olof, E-mail: ramstrom@kth.se [KTH-Royal Institute of Technology, Department of Chemistry, Teknikringen 30, S-10044 Stockholm (Sweden); Yan, Mingdi, E-mail: Mingdi_Yan@uml.edu [Department of Chemistry, University of Massachusetts Lowell, 1 University Ave., Lowell, MA 01854 (United States); KTH-Royal Institute of Technology, Department of Chemistry, Teknikringen 30, S-10044 Stockholm (Sweden)

    2015-07-15

    Covalently immobilized poly(4-vinylphenol) (PVP) monolayer films were fabricated by spin coating PVP on perfluorophenyl azide (PFPA)-functionalized surfaces followed by UV irradiation. The pH-responsive behavior of these PVP ultrathin films was evaluated by ellipsometry, quartz crystal microbalance (QCM) and surface plasmon resonance (SPR). By monitoring the responses of these films to pH in situ, the ionization constant of the monolayer thin films was obtained. The apparent pK{sub a} value of these covalently immobilized PVP monolayers, 13.4 by SPR, was 3 units higher than that of the free polymer in aqueous solution.

  4. Strategic petroleum reserve site environmental report for calendar year 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-31

    The purpose of this Site Environmental Report (SER) is to characterize site environmental management performance, confirm compliance with environmental standards and requirements, and highlight significant programs and efforts. Included in this report is a description of each site`s environment, an overview of the Strategic Petroleum Reserve (SPR) environmental program, and a recapitulation of special environmental activities and events associated with each SPR site during 1995. Two of these highlights include decommissioning of 3 the weeks Island facility, involving the disposition of 11.6 million m{sup 3} (73 million barrels) of crude oil inventory, as well as the degasification of over 4.5 million m{sup 3} (30 million barrels) of crude oil inventory at the Bryan Mound and West Hackberry facilities. The decision to decommission the weeks Island facility is a result of diminishing mine integrity from ground water intrusion. Transfer of Weeks Island oil began in November, 1995 with 2.0 million m{sup 3} (12.5 million barrels) transferred by December 31, 1995. Degasifying the crude oil is a major pollution prevention initiative because it will reduce potentially harmful emissions that would occur during oil movements by three or more orders of magnitude. Spills to the environment, another major topic, indicates a positive trend. There were only two reportable oil and three reportable brine spills during 1995, down from a total of 10 reportable spills in 1994. Total volume of oil spilled in 1995 was 56.3 m{sup 3} (354 barrels), and the total volume of brine spilled was 131.1 m{sup 3} (825 barrels). The longer term trend for oil and brine spills has declined substantially from 27 in 1990 down to five in 1995. All of the spills were reported to appropriate agencies and immediately cleaned up, with no long term impacts observed.

  5. [Modeling of the financial reserves required by the livestock disease compensation fund of Lower Saxony for rebates in the course of disease outbreaks incorporating spatial restriction zones].

    Science.gov (United States)

    Denzin, Nicolai; Gerdes, Ursula

    2015-01-01

    One of the tasks of the livestock disease compensation funds of the federal states in Germany is the financial compensation of livestock holders for livestock losses and costs incurred for disease control measures due to certain diseases. Usually, one half of these services are financed through financial reserves built up with the contributions paid by the owners of the respective animal species. The other half is covered by the federal state itself. But there is hardly any reference to how to calculate aforementioned financial reserves. Basically, following an approach presented recently regarding estimations concerning the compensation fund of the federal state of Saxony-Anhalt, in a stochastic modeling of the required reserves concerning the fund of Lower Saxony the anticipated costs within the spatial restriction zones allocated to outbreaks were incorporated for the first time. The overall costs (including the federal state's stakes), the share of the comnensation fund (required reserves) and the the partial costs for a total of 25 categories and subcategories and subcategories of livestock species making up the latter were estimated. It became evident that overall costs/the share of the fund were particularly determined among the diseases by foot-and-mouth disease and among the cost factors by the costs incurred for the compensation of livestock value within the areas surrounding the outbreaks in which all susceptible animals are killed (culling zone). The 80th, 90 and 95th percentile of the established probability distribution of the overall costs referred to a financial volume of about 312, 409 and 540 million euro, while the respective percentiles of the probability distribution of the required reserves of the compensation fund amounted to 175, 225 and 296 million euro.

  6. Strategic Petroleum Reserve, annual site environmental report for calendar year 1991

    International Nuclear Information System (INIS)

    1992-06-01

    This report, provided annually in accordance with DOE Order 5400.1, summarizes monitoring data collected to assess Strategic Petroleum Reserve (SPR) impacts on the environment. The report serves as a management tool for mitigating such impacts, thus serving the public interest by ensuring environmentally sound operation of the SPR. Included in this report is a description of each site's environment, an overview of the SPR environmental program, and a recapitulation of special environmental activities and events associated with each SPR site during 1990. The active permits and the results of the environmental monitoring program (i.e., air, surface vater, groundwater, and water discharges) are discussed within each section by site. The quality assurance program is presented which includes results from laboratory and field audits and studies performed internally and by regulatory agencies. In general, no significant adverse environmental impact resulted from any SPR activities during 1990. Environmental areas of concern, such as potential groundwater contamination, are fully addressed in the applicable section by site. The SPR continues to maintain an overall excellent environmental record

  7. Strategic Petroleum Reserve annual site environmental report for calendar year 1992

    Energy Technology Data Exchange (ETDEWEB)

    1993-06-01

    This report, provided annually in accordance with DOE Order 5400.1, summarizes monitoring data collected to assess Strategic Petroleum Reserve (SPR) impacts on the environment. The report serves as a management tool for mitigating such impacts, thus serving the public interest by ensuring environmentally sound operation of the SPR. Included in this report is a description of each site`s environment, an overview of the SPR environmental program, and a recapitulation of special environmental activities and events associated with each SPR site during 1992. The active permits and the results of the environmental monitoring program (i.e., air, surface water, ground water, and water discharges) are discussed within each section by site. The quality assurance program is presented which includes results from laboratory and field audits and studies performed internally and by regulatory agencies. In general, no significant adverse environmental impact resulted from any SPR activities during 1992. Environmental areas of concern, such as potential ground water contamination, are fully addressed in the applicable section by site. The SPR continues to maintain an overall excellent environmental record.

  8. Strategic Petroleum Reserve annual site environmental report for calendar year 1992

    International Nuclear Information System (INIS)

    1993-06-01

    This report, provided annually in accordance with DOE Order 5400.1, summarizes monitoring data collected to assess Strategic Petroleum Reserve (SPR) impacts on the environment. The report serves as a management tool for mitigating such impacts, thus serving the public interest by ensuring environmentally sound operation of the SPR. Included in this report is a description of each site's environment, an overview of the SPR environmental program, and a recapitulation of special environmental activities and events associated with each SPR site during 1992. The active permits and the results of the environmental monitoring program (i.e., air, surface water, ground water, and water discharges) are discussed within each section by site. The quality assurance program is presented which includes results from laboratory and field audits and studies performed internally and by regulatory agencies. In general, no significant adverse environmental impact resulted from any SPR activities during 1992. Environmental areas of concern, such as potential ground water contamination, are fully addressed in the applicable section by site. The SPR continues to maintain an overall excellent environmental record

  9. Gold nanoparticle-enhanced multiplexed imaging surface plasmon resonance (iSPR) detection of Fusarium mycotoxins in wheat

    Science.gov (United States)

    A rapid, sensitive and multiplexed imaging surface plasmon resonance (iSPR) biosensor assay was developed and validated for three Fusarium toxins, deoxynivalenol (DON), zearalenone (ZEA) and T-2 toxin. The iSPR assay was based on a competitive inhibition format with secondary antibodies (Ab2) conjug...

  10. Detection of mycotoxins using imaging surface plasmon resonance (iSPR)

    Science.gov (United States)

    Significant progress has been made in the development of biosensors that can be used to detect mycotoxins. One technology that has been extensively tested is surface plasmon resonance (SPR). In 2003 a multi-toxin method was reported that detected aflatoxin B1 (AFB1), zearalenone (ZEA), fumonisin B1 ...

  11. Binding of leachable components of polymethyl methacrylate (PMMA) and peptide on modified SPR chip

    International Nuclear Information System (INIS)

    Szaloki, M; Hegedus, Cs; Vitalyos, G; Harfalvi, J

    2013-01-01

    Many types of polymers are often used in dentistry, which may cause allergic reaction, mainly methyl methacrylate allergy due to the leachable, degradable components of polymerized dental products. The aim of this study was to investigate the interaction between the leachable components of PMMA and peptides by Fourier-transform Surface Plasmon Resonance (FT SPR). In our previous work binding of oligopeptides (Ph.D.-7 and Ph.D.-12 Peptide Library Kit) was investigated to PMMA surface by phage display technique. It was found that oligopeptides bounded specifically to PMMA surface. The most common amino acids were leucine and proline inside the amino acids sequences of DNA of phages. The binding of haptens, as formaldehyde and methacrylic acid, to frequent amino acids was to investigate on the modified gold SPR chip. Self assembled monolayer (SAM) modified the surface of gold chip and ensured the specific binding between the haptens and amino acids. It was found that amino acids bounded to modified SPR gold and the haptens bounded to amino acids by creating multilayer on the chip surface. By the application of phage display and SPR modern bioanalytical methods the interaction between allergens and peptides can be investigated

  12. 75 FR 10807 - Subcommittee on Procedures Reviews (SPR), Advisory Board on Radiation and Worker Health (ABRWH...

    Science.gov (United States)

    2010-03-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Subcommittee on Procedures Reviews (SPR), Advisory Board on Radiation and Worker Health (ABRWH), National Institute for Occupational Safety and Health (NIOSH) In accordance with section 10(a)(2) of the Federal Advisory Committee...

  13. Combinations of SPR and MS for Characterizations of Native and Recombinant Proteins in Cell Lysates

    DEFF Research Database (Denmark)

    Borch, Jonas; Roepstorff, Peter

    2006-01-01

    of 14-3-3 proteins in order to test their activity. Specific binding of recombinant and native 14-3-3 proteins in complex mixtures to immobilized phosphopeptides and subsequent elution was also tested by SPR-MS. Ammonium sulfate precipitate fractions from lysates of E. coli expressing 14-3-3 protein...

  14. Surface Plasmon Resonance (SPR Phenomenon of the Oxidizing and Reducing Polypyrrole

    Directory of Open Access Journals (Sweden)

    Nurlaila Rajabiah

    2016-12-01

    Full Text Available Surface Plasmon Resonance (SPR phenomenon of the oxidizing and reducing polypyrrole (PPy have been observed using a modified Au/PPy Kretschmann configuration. The observation was carried out through simulation Winspall 3.02 software and compared with some experimental data refractive index (n, absorbance index (, and thickness (τ reported in other literatures with spectroscopy ellipsometry. This simulation assumed that the SPR system use BK-7 halfcylinder prism (n= 1,515 and the laser beam was generated by HeNe (λ= 632,8 nm. The result showed that the optimum layer thickness of polypyrrole with neutral electrolyte solution in the reduction state is of about 20 nm. The polypyrrole with an acid solution in the oxidation state showed that the reflectivity curve is sharper and the width of the curve is smaller than the neutral electrolyte solution in the reduction state with the SPR angle of about 46,810 and the reflectivity value of about 0,217. Polypyrrole in a state of oxidation and reduction, related to the absorption, film thickness, and dielectric constant of materials, affected to the SPR angle shift and dip curve

  15. Effect of sulfasalazine on human neuroblastoma: analysis of sepiapterin reductase (SPR) as a new therapeutic target

    International Nuclear Information System (INIS)

    Yco, Lisette P.; Geerts, Dirk; Mocz, Gabor; Koster, Jan; Bachmann, André S.

    2015-01-01

    Neuroblastoma (NB) is an aggressive childhood malignancy in children up to 5 years of age. High-stage tumors frequently relapse even after aggressive multimodal treatment, and then show therapy resistance, typically resulting in patient death. New molecular-targeted compounds that effectively suppress tumor growth and prevent relapse with more efficacy are urgently needed. We and others previously showed that polyamines (PA) like spermidine and spermine are essential for NB tumorigenesis and that DFMO, an inhibitor of the key PA synthesis gene product ODC, is effective both in vitro and in vivo, securing its evaluation in NB clinical trials. To find additional compounds interfering with PA biosynthesis, we tested sulfasalazine (SSZ), an FDA-approved salicylate-based anti-inflammatory and immune-modulatory drug, recently identified to inhibit sepiapterin reductase (SPR). We earlier presented evidence for a physical interaction between ODC and SPR and we showed that RNAi-mediated knockdown of SPR expression significantly reduced native ODC enzyme activity and impeded NB cell proliferation. Human NB mRNA expression datasets in the public domain were analyzed using the R2 platform. Cell viability, isobologram, and combination index analyses as a result of SSZ treatment with our without DFMO were carried out in NB cell cultures. Molecular protein-ligand docking was achieved using the GRAMM algorithm. Statistical analyses were performed with the Kruskal-Wallis test, 2log Pearson test, and Student’s t test. In this study, we show the clinical relevance of SPR in human NB tumors. We found that high SPR expression is significantly correlated to unfavorable NB characteristics like high age at diagnosis, MYCN amplification, and high INSS stage. SSZ inhibits the growth of NB cells in vitro, presumably due to the inhibition of SPR as predicted by computational docking of SSZ into SPR. Importantly, the combination of SSZ with DFMO produces synergistic antiproliferative effects

  16. New insights into glycopeptide antibiotic binding to cell wall precursors using SPR and NMR spectroscopy.

    Science.gov (United States)

    Treviño, Juan; Bayón, Carlos; Ardá, Ana; Marinelli, Flavia; Gandolfi, Raffaella; Molinari, Francesco; Jimenez-Barbero, Jesús; Hernáiz, María J

    2014-06-10

    Glycopeptide antibiotics, such as vancomycin and teicoplanin, are used to treat life-threatening infections caused by multidrug-resistant Gram-positive pathogens. They inhibit bacterial cell wall biosynthesis by binding to the D-Ala-D-Ala C-terminus of peptidoglycan precursors. Vancomycin-resistant bacteria replace the dipeptide with the D-Ala-D-Lac depsipeptide, thus reducing the binding affinity of the antibiotics with their molecular targets. Herein, studies of the interaction of teicoplanin, teicoplanin-like A40926, and of their semisynthetic derivatives (mideplanin, MDL63,246, dalbavancin) with peptide analogues of cell-wall precursors by NMR spectroscopy and surface plasmon resonance (SPR) are reported. NMR spectroscopy revealed the existence of two different complexes in solution, when the different glycopeptides interact with Ac2KdAlaDAlaOH. Despite the NMR experimental conditions, which are different from those employed for the SPR measurements, the NMR spectroscopy results parallel those deduced in the chip with respect to the drastic binding difference existing between the D-Ala and the D-Lac terminating analogues, confirming that all these antibiotics share the same primary molecular mechanism of action and resistance. Kinetic analysis of the interaction between the glycopeptide antibiotics and immobilized AcKdAlaDAlaOH by SPR suggest a dimerization process that was not observed by NMR spectroscopy in DMSO solution. Moreover, in SPR, all glycopeptides with a hydrophobic acyl chain present stronger binding with a hydrophobic surface than vancomycin, indicating that additional interactions through the employed surface are involved. In conclusion, SPR provides a tool to differentiate between vancomycin and other glycopeptides, and the calculated binding affinities at the surface seem to be more relevant to in vitro antimicrobial activity than the estimations from NMR spectroscopy analysis. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Detection of phenols in potable water using SPR and specific receptors

    Energy Technology Data Exchange (ETDEWEB)

    Oliver, Jennifer Valerie

    2002-07-01

    The potential of thin films of a range of molecular receptors for surface plasmon resonance (SPR) sensing of a range of phenolic molecules in water has been explored. Receptors included molecular clips based on diarylglycouril units with two aromatic 'walls'; and polyalkylviologen (PAV) and cyclobis(paraquat-p-phenylene) (CPP) dications, two examples with polystyrene sulphonate (PSS) counterions. Films containing sulphonated polycyclodextrins were also evaluated. Target phenols included phenol, three benzene diols and two triols, three hydroxylated biphenyls and a range of related molecules. Receptor films were spin-coated, at up to 10,000rpm, as thin films (<200nm) onto glass slides coated with 48nm of silver. Effects of aqueous analytes on the position and profile of their SPR were examined by goniometer scanning and fixed angle measurement of intensity changes using a 632.8nm laser. A novel CCD array detector, utilising LED narrow band illumination peaking at 654nm, later yielded whole curve, real-time observations. Fixed-angle SPR responses of all viologen film types tested varied in direction, size and rate for different phenols, and depended on both the concentration of the phenol and on the age of its aqueous solution, permitting detection down to 10ppm. GC/MS studies confirmed the presence of polyphenols as oxidatively coupled phenolic breakdown products in the aged solutions. Greater sensitivity to polyphenols than to the original monomers was observed. The mechanistic basis of these observations is discussed with reference to SPR responses of the receptors to a series of model compounds designed to clarify the relative roles of hydrogen bonding, charge transfer and {pi}-{pi} interactions. Theoretical modelling of the responses has also been undertaken. Based on these results, time-dependent SPR response patterns for films of three different receptors were shown to permit unambiguous identification of simple phenols in water. The potential of

  18. An organizational survey of the Strategic Petroleum Reserve. [Organizational survey in preparation for an upcoming Tiger Team Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Shurberg, D.A.; Haber, S.B.

    1992-01-01

    At the request of the management of the Strategic Petroleum Reserve (SPR), an Organizational Survey (OS), identical to the one that has been used prior to Tiger Team Assessments at other Department Energy facilities, was administered at SPR independent of a Tiger Team Assessment. The OS measured employees' opinions on subjects such as organizational culture, communication, commitment, group cohesion, coordination, safety, environmental issues, and job satisfaction. The result of this work was a quantitative measure of these variables at the SPR site. SPR management intends to utilize these results in their self-assessment process in preparation for an upcoming Tiger Team Assessment. This report presents these results and discusses their interpretation.

  19. What's an ARAR?exclamation point: Regulatory requirements for CERCLA remedial activities at D ampersand D sites on the Oak Ridge Reservation

    International Nuclear Information System (INIS)

    Houlberg, L.M.; Etnier, E.L.

    1994-01-01

    Many government-owned facilities that supported early nuclear energy research and defense programs have no current use and have been retired. Some of these facilities have residual radioactive or chemical contamination that require remediation. The Department of Energy (DOE) Decontamination and Decommissioning (D ampersand D) Program is responsible for managing these surplus facilities. Remedial activities for contaminated environs and inactive land-based units (e.g., landfills, surface impoundments) at the Oak Ridge Reservation (ORR) are conducted under the direction of the Environmental Restoration (ER) Program

  20. Enhancement of the pathogenicity of Staphylococcus aureus strain Newman by a small noncoding RNA SprX1.

    Science.gov (United States)

    Kathirvel, Manikandan; Buchad, Hasmatbanu; Nair, Mrinalini

    2016-12-01

    The pathogenesis of Staphylococcus aureus from local infection to systemic dissemination involves a range of virulence factors including structural and secreted products. Among various control mechanisms, small noncoding RNAs are involved in the regulation of multiple pathogenicity factors in S. aureus. The sRNA SprX which is encoded in the pathogenicity island of methicillin-susceptible S. aureus strain Newman and was shown to influence antibiotic resistance previously, upregulated the expression of virulence genes, especially the cell wall-associated clumping factor B (ClfB) and delta hemolysin (Hld). Bioinformatic analysis revealed several multiple mRNAs associated with pathogenicity as targets for SprX1, one of the three copies of sprX. Both overexpression and chromosomal disruption of sprX1 supported the scheme of upregulation of clfB and hld expression. Altered expression of SprX1 altered the levels of Hld and ClfB mRNAs, hemolysis, clumping of cells, biofilm formation by plate adhesion studies and confocal microscopic analysis as well as infection pathology of modified strains in mice models. ClfB and Hld mRNAs interacted directly with SprX1 in in vitro assays. Increased level of the regulatory RNA, namely RNAIII, that comprises Hld mRNA and also regulates the biofilm formation, indicates that SprX1 may also function through RNAIII for regulating virulence factors. An immunodominant protein, antigen A, was downregulated by SprX1 in two-dimensional electrophoresis. Taken together, these results signify the role of sRNA SprX in the pathogenicity of S. aureus Newman.

  1. A model based on stochastic dynamic programming for determining China's optimal strategic petroleum reserve policy

    International Nuclear Information System (INIS)

    Zhang Xiaobing; Fan Ying; Wei Yiming

    2009-01-01

    China's Strategic Petroleum Reserve (SPR) is currently being prepared. But how large the optimal stockpile size for China should be, what the best acquisition strategies are, how to release the reserve if a disruption occurs, and other related issues still need to be studied in detail. In this paper, we develop a stochastic dynamic programming model based on a total potential cost function of establishing SPRs to evaluate the optimal SPR policy for China. Using this model, empirical results are presented for the optimal size of China's SPR and the best acquisition and drawdown strategies for a few specific cases. The results show that with comprehensive consideration, the optimal SPR size for China is around 320 million barrels. This size is equivalent to about 90 days of net oil import amount in 2006 and should be reached in the year 2017, three years earlier than the national goal, which implies that the need for China to fill the SPR is probably more pressing; the best stockpile release action in a disruption is related to the disruption levels and expected continuation probabilities. The information provided by the results will be useful for decision makers.

  2. Comparative SPR study on the effect of nanomaterials on the biological activity of adsorbed proteins

    International Nuclear Information System (INIS)

    Mei, Q.; Chen, Y.; Hong, J.; Chen, H.; Ding, X.; Yin, Y.; Koh, K.; Lee, J.

    2012-01-01

    Bioactivity of proteins is evaluated to test the adverse effects of nanoparticles interjected into biological systems. Surface plasmon resonance (SPR) spectroscopy detects binding affinity that is normally related to biological activity. Utilizing SPR spectroscopy, a concise testing matrix is established by investigating the adsorption level of bovine serum albumin (BSA) and anti-BSA on the surface covered with 11-mercaptoundecanoic acid (MUA); magnetic nanoparticles (MNPs) and single-walled carbon nanotubes (SWCNTs), respectively. The immunoactivity of BSA on MNPs and SWCNT decreased by 18 % and 5 %, respectively, compared to that on the gold film modified with MUA. This indicates that MNPs cause a considerable loss of biological activity of adsorbed protein. This effect can be utilized for practical applications on detailed biophysical research and nanotoxicity studies. (author)

  3. Immobilization of homogeneous monomeric, oligomeric and fibrillar Aβ species for reliable SPR measurements.

    Directory of Open Access Journals (Sweden)

    Daniel Frenzel

    Full Text Available There is strong evidence that the amyloid-beta peptide (Aβ plays a central role in the pathogenesis of Alzheimer's disease (AD. In this context, a detailed quantitative description of the interactions with different Aβ species is essential for characterization of physiological and artificial ligands. However, the high aggregation propensity of Aβ in concert with its susceptibility to structural changes due to even slight changes in solution conditions has impeded surface plasmon resonance (SPR studies with homogeneous Aβ conformer species. Here, we have adapted the experimental procedures to state-of-the-art techniques and established novel approaches to reliably overcome the aforementioned challenges. We show that the application of density gradient centrifugation (DGC for sample purification and the use of a single chain variable fragment (scFv of a monoclonal antibody directed against the amino-terminus of Aβ allows reliable SPR measurements and quality control of the immobilized Aβ aggregate species at any step throughout the experiment.

  4. Estimation of optical constants of a bio-thin layer (onion epidermis), using SPR spectroscopy

    International Nuclear Information System (INIS)

    Rehman, Saif-ur-; Hayashi, Shinji; Sekkat, Zouheir; Mumtaz, Huma; Shaukat, S F

    2014-01-01

    We estimate the optical constants of a biological thin layer (Allium cepa) by surface plasmon resonance (SPR) spectroscopy. For this study, the fresh inner thin epidermis of an onion bulb was used and stacked directly on gold (Au) and silver (Ag) film surfaces in order to identify the shift in SPR mode of each metal film at an operating wavelength of 632.8 nm. The thickness and dielectric constants of the biological thin layer were determined by matching the experimental SPR curves to theoretical ones. The thickness and roughness of bare Au and Ag thin films were also measured by atomic force microscopy (AFM); the results of which are in good agreement with those obtained through experiment. Due to the high surface roughness of the natural onion epidermis layer, AFM could not measure the exact thickness of an onion epidermis. It is estimated that the value of the real part of the dielectric constant of an onion epidermis is between the dielectric constants of water and air. (paper)

  5. [Application of exercise therapy on rehabilitation after selective posterior rhizotomy (SPR) in children with cerebral palsy].

    Science.gov (United States)

    Mu, Xiao-Hong; Xu, Lin; Xu, Shi-Gang; Cao, Xu; Zhang, Peng; Zheng, Chen-Ying; Zhou, Li; Li, Xiao-Ping; Chen, Jiang

    2009-09-01

    To observe the clinical effect of exercise therapy on rehabilitation after selective posterior rhizotomy (SPR) in children with cerebral palsy, so as to provide reliable rehabilitation method for children with cerebral palsy. Two hundred and twenty-six children with cerebral palsy were treated in the study during September 2003 to April 2007. All the patients were randomly divided into the training and control groups. There were 113 patients in the treatment group, including 66 males and 47 females, ranging in age from 3 to 8 years, with an average of (6.5 +/- 1.2) years, and the patients were treated with SPR as well as exercise therapy. Among 113 patients in the control group, 59 patients were male and 54 patients were female, ranging in age from 3 to 10 years, with an average of (6.9 +/- 1.5) years, and the patients were treated with SPR simply. Gross Motor Function Measure (GMFM), passive range of motion and muscle tension were used to evaluate therapeutic effects before and after treatment for both groups. All the patients were followed up for 6 to 18 months (averaged 8 months). There were significant improvements in training group compared with the control group on GMFM (134.29 +/- 46.43, P children with cerebral palsy, which can decrease spasticity and muscle tension and improve motor function.

  6. The SPR detection of Salmonella enteritidis in food using aptamers as recongnition elements

    Science.gov (United States)

    Di, W. T.; Du, X. W.; Pan, M. F.; Wang, J. P.

    2017-09-01

    In this experiment, a fast, accurate, non-destructive, unmarked and simple-operation detection method for Salmonella enteritidis in food was established by the BI-3000 plasma resonance biosensor (SPR). This article establishes a method of using nucleic acid aptamer as immune recognition element in SPR which can be employed to detect Salmonella enteritidis in food for the first time. The experimental conditions were screened and the experimental scheme was validated and applied. The best flow rate was 5μL/min, the best concentration of the aptamers was 180mM, and the best regenerating solution was the 20mM NaOH. This method had almost no cross-reactivity. Besides, we established a standard curve of Salmonella enteritidis and SPR signal, with the detection limit of 2 cfu/mL. Finally, we tested the samples of chicken, pork, shrimp and fish purchased from supermarkets. The method has the advantages of short time, low detection limit and easy operation, which can be used for a large number of food samples.

  7. Effect of Fe3O4 Magnetic Nanoparticle Concentration on the Signal of Surface Plasmon Resonance (SPR) Spectroscopy

    Science.gov (United States)

    Oktivina, M.; Nurrohman, D. T.; Rinto, A. N. Q. Z.; Suharyadi, E.; Abraha, K.

    2017-05-01

    Effect of Fe3O4 magnetic nanoparticle concentration on the signal of surface plasmon resonance (SPR) spectra has been successfully observed. The Fe3O4 nanoparticles with a particle size of about 10.5 ± 0.2 nm were used as active materials to increase the SPR response. X-ray diffraction (XRD) pattern showed that Fe3O4 nanoparticles have a high degree of crystallinity with spinel structure. The SPR system was successfully set up by using a glass prism coupler in a Kretschmann configuration in which gold (Au) thin film was thermally evaporated on the prism base. A green laser of wavelength 543 nm was used as light source. The angular scan in the attenuated total reflection (ATR) spectra showed a dropping intensity. Those things clearly indicated the appearance of SPR coupling phenomenon on the interface of Au thin film. The SPR spectra of fixed Au masses were also performed with same angular positions of dips. The Fe3O4 nanoparticles were deposited on gold thin film as a third layer which was synthesized via co-precipitation method. Hence, it was observed that the variation of Fe3O4 concentration affected the SPR spectra profile. The concentrations of Fe3O4 nanoparticles are 1, 3, 5, 7, 9, and 11 mg/ml which correspond to the angle shift of 0.1°, 0.3°, 0.5°, 0.7°, 0.9°, and 1.0°, respectively. The SPR angle of the dip was shifted to higher value due to change of refractive index of the medium as Fe3O4 nanoparticles concentration increases. Based on this result, we can conclude that the angle shift of SPR increases with increasing concentration of Fe3O4 nanoparticles.

  8. Bryan Mound SPR cavern 113 remedial leach stage 1 analysis.

    Energy Technology Data Exchange (ETDEWEB)

    Rudeen, David Keith; Weber, Paula D.; Lord, David L.

    2013-08-01

    The U.S. Strategic Petroleum Reserve implemented the first stage of a leach plan in 2011-2012 to expand storage volume in the existing Bryan Mound 113 cavern from a starting volume of 7.4 million barrels (MMB) to its design volume of 11.2 MMB. The first stage was terminated several months earlier than expected in August, 2012, as the upper section of the leach zone expanded outward more quickly than design. The oil-brine interface was then re-positioned with the intent to resume leaching in the second stage configuration. This report evaluates the as-built configuration of the cavern at the end of the first stage, and recommends changes to the second stage plan in order to accommodate for the variance between the first stage plan and the as-built cavern. SANSMIC leach code simulations are presented and compared with sonar surveys in order to aid in the analysis and offer projections of likely outcomes from the revised plan for the second stage leach.

  9. SPR studies of the adsorption of silver/bovine serum albumin nanoparticles (Ag/BSA NPs) onto the model biological substrates.

    Science.gov (United States)

    Bhan, Chandra; Brower, Tina Louise; Raghavan, Dharmaraj

    2013-07-15

    The primary objective of this study is to investigate the interactive forces that promote the adsorption of bio-conjugated nanoparticles onto proteins. To elucidate the interactive forces, we demonstrate an approach using synthetic and model biological surfaces to study adsorption of bio-conjugated nanoparticles. Real-time adsorption of BSA conjugated silver nanoparticles (Ag/BSA NPs) on the immobilized substrates was followed by surface plasmon resonance (SPR). The extent of adsorption of the nanoparticles on the synthetic surface was found to be larger for self-assembled monolayers (SAMs) with ionizable terminal groups and lower for SAMs with unionizable terminal groups. For model biological substrate, the extent of nanoparticles adsorption was found to relate to the pKa of immobilized proteins. For collagen immobilized substrate, the adsorption of Ag/BSA nanoparticles showed a significantly higher SPR response than that of free BSA. The extent of nanoparticles adsorption on the collagen immobilized substrate was also influenced by the type and concentration of electrolyte used in dispersing nanoparticles. Our findings indicate that the adsorption of nanoparticles to immobilized surface has contributions from electrostatic interactions, hydrophobic, and/or hydrogen bonding. This work provides the framework to study interactions that may arise when bio-conjugated nanoparticles are transported in biological systems. Copyright © 2013 Elsevier Inc. All rights reserved.

  10. Report to Congress on the feasibility of establishing a heating oil component to the Strategic Petroleum Reserve. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-06-01

    In the Autumn of 1996, consumers and Members of Congress from the Northeast expressed concern about high prices for heating oil and historically low levels of inventories. Some Members of Congress advocated building a Federal inventory of heating oil as part of the Strategic Petroleum Reserve (SPR). Regional reserves are authorized as part of the SPR for import dependent regions by the Energy Policy and Conservation Act. In response, the Department of Energy (DOE) proposed a series of studies related to heating fuels, including a study of the desirability, feasibility, and cost of creating a Federal reserve containing distillate fuel. This report documents that study.

  11. Environmental Survey preliminary report, Strategic Petroleum Reserve, Texas and Louisiana Gulf Coast

    Energy Technology Data Exchange (ETDEWEB)

    1989-01-01

    This report presents the preliminary environmental findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Strategic Petroleum Reserve (SPR), located in Louisiana and Texas, and conducted in two segments from November 30 through December 11, 1987, and February 1 through 10, 1988. The Survey is being conducted by a multidisciplinary team of environmental specialists led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team specialists are outside experts being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with SPR. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involved the review of existing site environmental data, observations of the operations carried on at SPR, and interviews with site personnel. The Survey team has developed a Sampling and Analysis Plan to assist in further assessing specific environmental problems identified during its on-site activities. The Sampling and Analysis Plan will be executed by Idaho National Engineering Laboratory. When completed, the results will be incorporated into the SPR Survey findings for inclusion into the Environmental Survey Summary Report. The Summary Report will reflect the final determinations of the SPR Survey and the other DOE site-specific Surveys. 200 refs., 50 figs., 30 tabs.

  12. Analysis of cavern and well stability at the West Hackberry SPR site using a full-dome model.

    Energy Technology Data Exchange (ETDEWEB)

    Sobolik, Steven R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-08-01

    This report presents computational analyses that simulate the structural response of caverns at the Strategic Petroleum Reserve (SPR) West Hackberry site. The cavern field comprises 22 caverns. Five caverns (6, 7, 8, 9, 11) were acquired from industry and have unusual shapes and a history dating back to 1946. The other 17 caverns (101-117) were leached according to SPR standards in the mid-1980s and have tall cylindrical shapes. The history of the caverns and their shapes are simulated in a three-dimensional geomechanics model of the site that predicts deformations, strains, and stresses. Future leaching scenarios corresponding to oil drawdowns using fresh water are also simulated by increasing the volume of the caverns. Cavern pressures are varied in the model to capture operational practices in the field. The results of the finite element model are interpreted to provide information on the current and future status of subsidence, well integrity, and cavern stability. The most significant results in this report are relevant to Cavern 6. The cavern is shaped like a bowl with a large ceiling span and is in close proximity to Cavern 9. The analyses predict tensile stresses at the edge of the ceiling during repressurization of Cavern 6 following workover conditions. During a workover the cavern is at low pressure to service a well. The wellhead pressures are atmospheric. When the workover is complete, the cavern is repressurized. The resulting elastic stresses are sufficient to cause tension around the edge of the large ceiling span. With time, these stresses relax to a compressive state because of salt creep. However, the potential for salt fracture and propagation exists, particularly towards Cavern 9. With only 200 feet of salt between the caverns, the operational consequences must be examined if the two caverns become connected. A critical time may be during a workover of Cavern 9 in part because of the operational vulnerabilities, but also because dilatant damage

  13. Pseudomonas resinovorans SPR1, a newly isolated strain with potential of transforming eugenol to vanillin and vanillic acid.

    Science.gov (United States)

    Ashengroph, Morahem; Nahvi, Iraj; Zarkesh-Esfahani, Hamid; Momenbeik, Fariborz

    2011-10-01

    In this study a novel strain was isolated with the capability to grow on eugenol as a source of carbon and energy. This strain was identified as Pseudomonas resinovorans (GenBank accession no. HQ198585) based on phenotypic characterization and phylogenetic analysis of 16S rDNA gene. The intermediates coniferyl alcohol, coniferyl aldehyde, ferulic acid, vanillin and vanillic acid were detected in the culture supernatant during eugenol biotransformation with this strain. The products were confirmed by thin layer chromatography (TLC), high performance liquid chromatography (HPLC) and spectral data achieved from UV-vis, FTIR and mass spectroscopy. Using eugenol as substrate and resting cells of P. resinovorans SPR1, which were harvested at the end of the exponential growth phase, without further optimization 0.24 g/L vanillin (molar yield of 10%) and 1.1g/L vanillic acid (molar yield of 44%) were produced after 30 h and 60 h biotransformation, respectively. The current work gives the first evidence for the eugenol biotransformation by P. resinovorans. Copyright © 2011 Elsevier B.V. All rights reserved.

  14. U.S. Strategic Petroleum Reserve Vapor Pressure Committee 2009 annual report.

    Energy Technology Data Exchange (ETDEWEB)

    Allen, Ray (Allen Energy Services, Inc., Longview, TX); Eldredge, Lisa (DynMcDermott Petroleum Operations, Harahan, LA); DeLuca, Charles (DynMcDermott Petroleum Operations, Harahan, LA); Mihalik, Patrick (DynMcDermott Petroleum Operations, Harahan, LA); Maldonado, Julio (U.S. Department of Energy, Harahan, LA); Lord, David L.; Rudeen, David Keith (GRAM, Inc., Albuquerque, NM); Berndsen, Gerard (U.S. Department of Energy, Harahan, LA)

    2010-05-01

    This report comprises an annual summary of activities under the U.S. Strategic Petroleum Reserve (SPR) Vapor Pressure Committee in FY2009. The committee provides guidance to senior project management on the issues of crude oil vapor pressure monitoring nd mitigation. The principal objectives of the vapor pressure program are, in the event of an SPR drawdown, to minimize the impact on the environment and assure worker safety and public health from crude oil vapor emissions. The annual report reviews key program areas ncluding monitoring program status, mitigation program status, new developments in measurements and modeling, and path forward including specific recommendations on cavern sampling for the next year. The contents of this report were first presented to SPR senior anagement in December 2009, in a deliverable from the vapor pressure committee. The current SAND report is an adaptation for the Sandia technical audience.

  15. Developmentally-regulated excision of the SPβ prophage reconstitutes a gene required for spore envelope maturation in Bacillus subtilis.

    Directory of Open Access Journals (Sweden)

    Kimihiro Abe

    2014-10-01

    Full Text Available Temperate phages infect bacteria by injecting their DNA into bacterial cells, where it becomes incorporated into the host genome as a prophage. In the genome of Bacillus subtilis 168, an active prophage, SPβ, is inserted into a polysaccharide synthesis gene, spsM. Here, we show that a rearrangement occurs during sporulation to reconstitute a functional composite spsM gene by precise excision of SPβ from the chromosome. SPβ excision requires a putative site-specific recombinase, SprA, and an accessory protein, SprB. A minimized SPβ, where all the SPβ genes were deleted, except sprA and sprB, retained the SPβ excision activity during sporulation, demonstrating that sprA and sprB are necessary and sufficient for the excision. While expression of sprA was observed during vegetative growth, sprB was induced during sporulation and upon mitomycin C treatment, which triggers the phage lytic cycle. We also demonstrated that overexpression of sprB (but not of sprA resulted in SPβ prophage excision without triggering the lytic cycle. These results suggest that sprB is the factor that controls the timing of phage excision. Furthermore, we provide evidence that spsM is essential for the addition of polysaccharides to the spore envelope. The presence of polysaccharides on the spore surface renders the spore hydrophilic in water. This property may be beneficial in allowing spores to disperse in natural environments via water flow. A similar rearrangement occurs in Bacillus amyloliquefaciens FZB42, where a SPβ-like element is excised during sporulation to reconstitute a polysaccharide synthesis gene, suggesting that this type of gene rearrangement is common in spore-forming bacteria because it can be spread by phage infection.

  16. Developmentally-Regulated Excision of the SPβ Prophage Reconstitutes a Gene Required for Spore Envelope Maturation in Bacillus subtilis

    Science.gov (United States)

    Abe, Kimihiro; Kawano, Yuta; Iwamoto, Keito; Arai, Kenji; Maruyama, Yuki; Eichenberger, Patrick; Sato, Tsutomu

    2014-01-01

    Temperate phages infect bacteria by injecting their DNA into bacterial cells, where it becomes incorporated into the host genome as a prophage. In the genome of Bacillus subtilis 168, an active prophage, SPβ, is inserted into a polysaccharide synthesis gene, spsM. Here, we show that a rearrangement occurs during sporulation to reconstitute a functional composite spsM gene by precise excision of SPβ from the chromosome. SPβ excision requires a putative site-specific recombinase, SprA, and an accessory protein, SprB. A minimized SPβ, where all the SPβ genes were deleted, except sprA and sprB, retained the SPβ excision activity during sporulation, demonstrating that sprA and sprB are necessary and sufficient for the excision. While expression of sprA was observed during vegetative growth, sprB was induced during sporulation and upon mitomycin C treatment, which triggers the phage lytic cycle. We also demonstrated that overexpression of sprB (but not of sprA) resulted in SPβ prophage excision without triggering the lytic cycle. These results suggest that sprB is the factor that controls the timing of phage excision. Furthermore, we provide evidence that spsM is essential for the addition of polysaccharides to the spore envelope. The presence of polysaccharides on the spore surface renders the spore hydrophilic in water. This property may be beneficial in allowing spores to disperse in natural environments via water flow. A similar rearrangement occurs in Bacillus amyloliquefaciens FZB42, where a SPβ-like element is excised during sporulation to reconstitute a polysaccharide synthesis gene, suggesting that this type of gene rearrangement is common in spore-forming bacteria because it can be spread by phage infection. PMID:25299644

  17. Applicable or Relevant and Appropriate Requirements (ARARs) for Remedial Action at the Oak Ridge Reservation: A compendium of major environmental laws

    International Nuclear Information System (INIS)

    Etnier, E.L.; McDonald, E.P.; Houlberg, L.M.

    1993-07-01

    Section 121 of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) of 1980 specifies that remedial actions for cleanup of hazardous substances must comply with applicable or relevant and appropriate requirements (ARARS) or standards under federal and state environmental laws. The US Department of Energy (DOE) Oak Ridge Reservation (ORR) was placed on the National Priorities List by the US Environmental Protection Agency (EPA) on November 21, 1989, effective December 21, 1989. As a result of this listing, DOE, EPA, and the Tennessee Department of Environment and Conservation have signed a Federal Facility Agreement (FFA) for the environmental restoration of the ORR. Section XXI(F) of the FFA calls for the preparation of a draft listing of all ARARs as mandated by CERCLA section 121. This report supplies a preliminary list of available federal and state ARARs that might be considered for remedial response at the ORR. A description of the terms ''applicable'' and ''relevant and appropriate'' is provided, as well as definitions of chemical-, location-, and action-specific ARARS. ARARs promulgated by the federal government and by the state of Tennessee are listed in tables. In addition, the major provisions of the Resource Conservation and Recovery Act, the Safe Drinking Water Act, the Clean Water Act, the Clean Air and other acts, as they apply to hazardous waste cleanup, are discussed. In the absence of ARARS, CERCLA section 121 provides for the use of nonpromulgated federal criteria, guidelines, and advisories in evaluating the human risk associated with remedial action alternatives. Such nonpromulgated standards are classified as ''to-be-considered'' (TBC) guidance. A ion of available guidance is given; summary tables fist the available federal standards and guidance information. In addition, the substantive contents of the DOE orders as they apply to remediation of radioactively contaminated sites are discussed as TBC guidance

  18. Applicable or Relevant and Appropriate Requirements (ARARs) for Remedial Action at the Oak Ridge Reservation: A compendium of major environmental laws. Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    Etnier, E.L.; McDonald, E.P.; Houlberg, L.M.

    1993-07-01

    Section 121 of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) of 1980 specifies that remedial actions for cleanup of hazardous substances must comply with applicable or relevant and appropriate requirements (ARARS) or standards under federal and state environmental laws. The US Department of Energy (DOE) Oak Ridge Reservation (ORR) was placed on the National Priorities List by the US Environmental Protection Agency (EPA) on November 21, 1989, effective December 21, 1989. As a result of this listing, DOE, EPA, and the Tennessee Department of Environment and Conservation have signed a Federal Facility Agreement (FFA) for the environmental restoration of the ORR. Section XXI(F) of the FFA calls for the preparation of a draft listing of all ARARs as mandated by CERCLA {section}121. This report supplies a preliminary list of available federal and state ARARs that might be considered for remedial response at the ORR. A description of the terms ``applicable`` and ``relevant and appropriate`` is provided, as well as definitions of chemical-, location-, and action-specific ARARS. ARARs promulgated by the federal government and by the state of Tennessee are listed in tables. In addition, the major provisions of the Resource Conservation and Recovery Act, the Safe Drinking Water Act, the Clean Water Act, the Clean Air and other acts, as they apply to hazardous waste cleanup, are discussed. In the absence of ARARS, CERCLA {section}121 provides for the use of nonpromulgated federal criteria, guidelines, and advisories in evaluating the human risk associated with remedial action alternatives. Such nonpromulgated standards are classified as ``to-be-considered`` (TBC) guidance. A ion of available guidance is given; summary tables fist the available federal standards and guidance information. In addition, the substantive contents of the DOE orders as they apply to remediation of radioactively contaminated sites are discussed as TBC guidance.

  19. The safety renovation on the control and protection system for 49-2 (SPR)

    International Nuclear Information System (INIS)

    Sun Xueliang; Wu Taosheng; Chen Kezhi; Zheng Wenyao; Hao Huaide

    1999-01-01

    The introduction of the safety renovation project of the control and protection system of the swimming-pool research reactor (SPR) is presented. An advanced control and protection system for 49-2 (SPR) has been designed, manufactured, installed and tested. In the design of the new system, the modern measuring and control techniques are employed and the national standards and nuclear safety codes are strictly followed. Protection variables and equipment are modified; Sensitivity increased about 1-2 orders of magnitude; at shutdown condition, 5 independent monitors indicate reactor power at the same time; It has good stability and anti-jamming ability. New type of auto-power adjusting system is of good quality; and the Minimum reactor power for patting into auto-mode is modified to be 10 W level instead of previous kw level. Thus the operation safety is ensured and sensitivity increased; added UPS as backup power supply ensures safe shutdown and the indication of the reactor power at reactor shutdown. This project is the first attempt of the renovation of the control and protection systems of the research reactors in China. The success of the two years safe operation of the new system would be of value for the reconstruction of other research reactors and for the design of the new Research Reactors

  20. Theoretical investigation on multilayer nanocomposite-based fiber optic SPR sensor

    Science.gov (United States)

    Shojaie, Ehsan; Madanipour, Khosro; Gharibzadeh, Azadeh; Abbasi, Shabnam

    2017-06-01

    In this work, a multilayer nanocomposite based fiber optic SPR sensor is considered and especially designed for CO2 gas detection. This proposed fiber sensor consists of fiber core, gold-silver alloy and the absorber layers. The investigation is based on the evaluation of the transmitted-power derived under the transfer matrix method and the multiple-reflection in the sensing area. In terms of sensitivity, the sensor performance is studied theoretically under various conditions related to the metal layer and its gold and silver nanoparticles to form a single alloy film. Effect of additional parameters such as the ratio of the alloy composition and the thickness of the alloy film on the performance of the SPR sensor is studied, as well. Finally, a four-layer structure is introduced to detect carbon dioxide gas. It contains core fiber, gold-silver alloy layer, an absorbent layer of carbon dioxide gas (KOH) and measurement environment. Lower price and size are the main advantages of using such a sensor in compare with commercial (NDIR) gas sensor. Theoretical results show by increasing the metal layer thickness the sensitivity of sensor is increased, and by increasing the ratio of the gold in alloy the sensitivity is decreased.

  1. Stability Modification of SPR Silver Nano-Chips by Alkaline Condensation of Aminopropyltriethoxysilane

    Directory of Open Access Journals (Sweden)

    M. Ghorbanpour

    2015-04-01

    Full Text Available The Silver SPR chip was modified by alkaline-silane condensation with aminopropyltriethoxysilane (APTES in NaOH aqueous solution at different times. Silver sputtered slides coated with APTES were immersed in NaOH solution, enabling us to produce silver surfaces homogeneously covered with APTES. The surface properties of grafted APTES on sputtered silver surface as a occasion of time were studied using SPR analysis, AFM and contact angle measurement. The mechanical and chemical stability of samples was assayed by tape test and NaCl test. The answers show that hydrolysis and condensation of APTES are activated in alkaline solution and lead to formation of a protective APTES layer on the surface of silver. The morphology of APTES on silver surface is a function of coverage density that is altered by changing time. At short times (< 30 min, APTES molecules physically adsorb to the surface leads to weak protection. At higher condensation times, APTES molecules chemically bond to the surface and each other leads to better protection.

  2. Aplikace pro vzdálenou správu Mikrotik RouterOS

    OpenAIRE

    Doležal, Jiří

    2012-01-01

    Tato bakalářská práce se zabývá návrhem a tvorbou aplikace pro vzdálenou správu MikroTik RouterOS. V rámci práce byla vytvořena aplikace umožňující konfiguraci síťových služeb směrovačů. Práce obsahuje návrh a implementaci aplikace v programovacím jazyce C#. Použitím frameworku Mono bylo dosaženo přenositelnosti aplikace mezi operačními systémy MS Windows a Linux. Aplikace využívá přehledné grafické uživatelské rozhraní pro snadnou správu zařízení s MikroTik RouterOS. This bachelor´s thesi...

  3. A SPR Aptasensor for Detection of Avian Influenza Virus H5N1

    Directory of Open Access Journals (Sweden)

    Huaguang Lu

    2012-09-01

    Full Text Available Rapid and specific detection of avian influenza virus (AIV is urgently needed due to the concerns over the potential outbreaks of highly pathogenic H5N1 influenza in animals and humans. Aptamers are artificial oligonucleic acids that can bind specific target molecules, and show comparable affinity for target viruses and better thermal stability than monoclonal antibodies. The objective of this research was to use a DNA-aptamer as the specific recognition element in a portable Surface Plasmon Resonance (SPR biosensor for rapid detection of AIV H5N1 in poultry swab samples. A SPR biosensor was fabricated using selected aptamers that were biotinylated and then immobilized on the sensor gold surface coated with streptavidin via streptavidin-biotin binding. The immobilized aptamers captured AIV H5N1 in a sample solution, which caused an increase in the refraction index (RI. After optimizing the streptavidin and aptamer parameters, the results showed that the RI value was linearly related (R2 = 0.99 to the concentration of AIV in the range of 0.128 to 1.28 HAU. Negligible signal ( < 4% of H5N1 was observed from six non-target AIV subtypes. The AIV H5N1 in poultry swab samples with concentrations of 0.128 to 12.8 HAU could be detected using this aptasensor in 1.5 h.

  4. Gold nanoparticles decorated on BaTiO3 as photocatalyst: effect of SPR and ferroelectricity

    Science.gov (United States)

    Miao, Zhilei; Chen, Lei; Wang, Rui; Yuan, Rongchun; Zhou, Fang; Lv, Pengfei; Zhang, Xiuyun; Wang, Qiang

    2018-02-01

    BaTiO3(BTO) powders with cubic(C) and tetragonal(T) crystalline structures were prepared by sol-gel method followed by calcination at different temperatures, and they were decorated with gold nanoparticles(AuNPs) to form Au-T-BTO and Au-C-BTO respectively. All the samples (C-BTO, T-BTO, Au-C-BTO and Au-T-BTO) were used as photo-catalysts for the degradation of Rhodamine B (RhB). Au-T-BTO exhibits the highest photocatalytic activity due to thecombined effect of surface plasmon resonance (SPR) and the ferroelectricity of the tetragonalphase BTO. The light absorption peaks at 500 to 600 nm verify the presence of SPR effect from Au NPs. Based on density functional theory (DFC) within the generalized gradient approximation (GGA) approach, it was demonstrated that the tetragonal phase BaTiO3 shows a spontaneous polarization with the calculated value of 0.34 C m-2, which is absent in thecubic phase. The internal space charge layer in tetragonal phase BTO enhances the separation of photoexcited carriers due to the spontaneous ferroelectric polarization, which also benefits photocatalytic activities.

  5. Dynamic SPR monitoring of yeast nuclear protein binding to a cis-regulatory element

    International Nuclear Information System (INIS)

    Mao, Grace; Brody, James P.

    2007-01-01

    Gene expression is controlled by protein complexes binding to short specific sequences of DNA, called cis-regulatory elements. Expression of most eukaryotic genes is controlled by dozens of these elements. Comprehensive identification and monitoring of these elements is a major goal of genomics. In pursuit of this goal, we are developing a surface plasmon resonance (SPR) based assay to identify and monitor cis-regulatory elements. To test whether we could reliably monitor protein binding to a regulatory element, we immobilized a 16 bp region of Saccharomyces cerevisiae chromosome 5 onto a gold surface. This 16 bp region of DNA is known to bind several proteins and thought to control expression of the gene RNR1, which varies through the cell cycle. We synchronized yeast cell cultures, and then sampled these cultures at a regular interval. These samples were processed to purify nuclear lysate, which was then exposed to the sensor. We found that nuclear protein binds this particular element of DNA at a significantly higher rate (as compared to unsynchronized cells) during G1 phase. Other time points show levels of DNA-nuclear protein binding similar to the unsynchronized control. We also measured the apparent association complex of the binding to be 0.014 s -1 . We conclude that (1) SPR-based assays can monitor DNA-nuclear protein binding and that (2) for this particular cis-regulatory element, maximum DNA-nuclear protein binding occurs during G1 phase

  6. Development of latent fingerprints on wet non-porous surfaces with SPR based on basic fuchsin dye

    Directory of Open Access Journals (Sweden)

    Richa Rohatgi

    2016-06-01

    Full Text Available Small particle reagent (SPR is a technique performed to detect latent fingerprints left on wet and moist surfaces based upon the reaction between fatty acid residuals present in the traces and hydrophobic tails of the specific reagent. Those tails are linked to a hydrophilic head of zinc carbonate based formulation to give coloured precipitate. In the present study, we have prepared a novel SPR formulation constituting of zinc carbonate based on basic fuchsin dye for the development of latent fingerprints on wet surfaces. It was shown to develop clear, sharp and detailed fingerprints on non-porous surfaces after these were immersed in water for up to 45 days. The ability of the present formulations to detect weak and chance prints not only enhances its utility, but also its potentiality in forensic casework investigations. The raw materials used to prepare the SPR are cost-effective and non-hazardous.

  7. Geomechanical Model Calibration Using Field Measurements for a Petroleum Reserve

    Science.gov (United States)

    Park, Byoung Yoon; Sobolik, Steven R.; Herrick, Courtney G.

    2018-03-01

    A finite element numerical analysis model has been constructed that consists of a mesh that effectively captures the geometries of Bayou Choctaw (BC) Strategic Petroleum Reserve (SPR) site and multimechanism deformation (M-D) salt constitutive model using the daily data of actual wellhead pressure and oil-brine interface location. The salt creep rate is not uniform in the salt dome, and the creep test data for BC salt are limited. Therefore, the model calibration is necessary to simulate the geomechanical behavior of the salt dome. The cavern volumetric closures of SPR caverns calculated from CAVEMAN are used as the field baseline measurement. The structure factor, A 2, and transient strain limit factor, K 0, in the M-D constitutive model are used for the calibration. The value of A 2, obtained experimentally from BC salt, and the value of K 0, obtained from Waste Isolation Pilot Plant salt, are used for the baseline values. To adjust the magnitude of A 2 and K 0, multiplication factors A 2 F and K 0 F are defined, respectively. The A 2 F and K 0 F values of the salt dome and salt drawdown skins surrounding each SPR cavern have been determined through a number of back analyses. The cavern volumetric closures calculated from this model correspond to the predictions from CAVEMAN for six SPR caverns. Therefore, this model is able to predict behaviors of the salt dome, caverns, caprock, and interbed layers. The geotechnical concerns associated with the BC site from this analysis will be explained in a follow-up paper.

  8. Geomechanical Simulation of Bayou Choctaw Strategic Petroleum Reserve - Model Calibration.

    Energy Technology Data Exchange (ETDEWEB)

    Park, Byoung [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-02-01

    A finite element numerical analysis model has been constructed that consists of a realistic mesh capturing the geometries of Bayou Choctaw (BC) Strategic Petroleum Reserve (SPR) site and multi - mechanism deformation ( M - D ) salt constitutive model using the daily data of actual wellhead pressure and oil - brine interface. The salt creep rate is not uniform in the salt dome, and the creep test data for BC salt is limited. Therefore, the model calibration is necessary to simulate the geomechanical behavior of the salt dome. The cavern volumetric closures of SPR caverns calculated from CAVEMAN are used for the field baseline measurement. The structure factor, A 2 , and transient strain limit factor, K 0 , in the M - D constitutive model are used for the calibration. The A 2 value obtained experimentally from the BC salt and K 0 value of Waste Isolation Pilot Plant (WIPP) salt are used for the baseline values. T o adjust the magnitude of A 2 and K 0 , multiplication factors A2F and K0F are defined, respectively. The A2F and K0F values of the salt dome and salt drawdown skins surrounding each SPR cavern have been determined through a number of back fitting analyses. The cavern volumetric closures calculated from this model correspond to the predictions from CAVEMAN for six SPR caverns. Therefore, this model is able to predict past and future geomechanical behaviors of the salt dome, caverns, caprock , and interbed layers. The geological concerns issued in the BC site will be explained from this model in a follow - up report .

  9. Production of a broad specificity antibody for the development and validation of an optical SPR screening method for free and intracellular microcystins and nodularin in cyanobacteria cultures.

    Science.gov (United States)

    Devlin, Shauna; Meneely, Julie P; Greer, Brett; Campbell, Katrina; Vasconcelos, Vitor; Elliott, Christopher T

    2014-05-01

    A highly sensitive broad specificity monoclonal antibody was produced and characterised for microcystin detection through the development of a rapid surface plasmon resonance (SPR) optical biosensor based immunoassay. The antibody displayed the following cross-reactivity: MC-LR 100%; MC-RR 108%; MC-YR 68%; MC-LA 69%; MC-LW 71%; MC-LF 68%; and Nodularin 94%. Microcystin-LR was covalently attached to a CM5 chip and with the monoclonal antibody was employed in a competitive 4 min injection assay to detect total microcystins in water samples below the WHO recommended limit (1 µg/L). A 'total microcystin' level was determined by measuring free and intracellular concentrations in cyanobacterial culture samples as this toxin is an endotoxin. Glass bead beating was used to lyse the cells as a rapid extraction procedure. This method was validated according to European Commission Decision 96/23/EC criteria. The method was proven to measure intracellular microcystin levels, the main source of the toxin, which often goes undetected by other analytical procedures and is advantageous in that it can be used for the monitoring of blooms to provide an early warning of toxicity. It was shown to be repeatable and reproducible, with recoveries from spiked samples ranging from 74 to 123%, and had % CVs below 10% for intra-assay analysis and 15% for inter-assay analysis. The detection capability of the assay was calculated as 0.5 ng/mL for extracellular toxins and 0.05 ng/mL for intracellular microcystins. A comparison of the SPR method with LC-MS/MS was achieved by testing six Microcystis aeruginosa cultures and this study yielded a correlation R(2) value of 0.9989. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. Layer-by-layer assembled multilayer of graphene/Prussian blue toward simultaneous electrochemical and SPR detection of H2O2

    DEFF Research Database (Denmark)

    Mao, Yan; Bao, Yu; Wang, Wei

    2011-01-01

    2O2) by electrochemical surface plasmon resonance (EC-SPR) spectroscopy. This real time EC-SPR technique can provide simultaneous monitoring of both optical SPR signal and electrochemical current responses upon injecting H2O2 into the reaction cell. The experimental results revealed that both...... the electrochemical and SPR signal exhibited splendid linear relationship to the concentration of the injected H2O2, and the detection limit could be up to 1μM....... layer-by-layer (LBL) assembly. The assembly process was confirmed by UV–vis spectroscopy and surface plasmon resonance (SPR) spectroscopy, which showed linear responses to the numbers of the deposited PFIL–GS/PB bilayers. Moreover, the as-prepared composite films were used to detect hydrogen peroxide (H...

  11. «[…] en enkel og saklig innføring i norsk språkhistorie» Språkhistorie som norskdidaktisk emne – et faghistorisk utsyn

    Directory of Open Access Journals (Sweden)

    Stian Hårstad

    2016-09-01

    Full Text Available Artikkelen tar for seg språkhistorie som norskdidaktisk emne i et faghistorisk perspektiv. På grunnlag av en lang rekke styringsdokumenter (læreplaner og studieplaner og fagdidaktisk og disiplinfaglig litteratur undersøkes hvordan språkets historiske dimensjoner har blitt tematisert som kunnskapsområde. Et hovedfunn i denne gjennomgangen er at det historiske (eller historiserende lengdesnittet har vært til stede gjennom hele 1900-tallet og fortsatt finnes i gjeldende læreplan – om enn med temmelig varierende vektlegging og detaljering. Læreplanene har i stor grad overlatt til praktikerne (lærerne og lærerutdannerne å avgrense hva de språkhistoriske emnene skal romme. Litteraturanalysen viser videre at den didaktiske refleksjonen på dette feltet bare unntaksvis har kommet på trykk, og denne begrensete språkhistorie-didaktiske debatten må forstås på bakgrunn av tilstanden i forsknings- og studiefaget.Nøkkelord: språkhistorie-didaktikk, språkdidaktikk, språkhistorie, norskdidaktikkAbstractThis article deals with language history as a didactic topic in the subject Norwegian as L1. On the basis of a wide range of documents (curricula and syllabi and didactic and disciplinary literature, the article seeks to examine how the historical dimensions of language have been treated as an area of knowledge. A main finding is that the historic (or historicizing perspective has been present through the entire 20th century and still can be found in the current curriculum – though the emphasis and itemization have varied significantly. The curricula have largely entrusted the practicians (the teachers and teacher educators with the powers to delineate the language history topics. The research review further shows that the didactic reflections within this field only sporadically have appeared in print, and this limited didactic discussion of language history must be understood on the background of the condition of the discipline

  12. 456 Hours to Train the Reserve Component: Analysis of the Impact of Increased Annual Training Requirements on 4th Assault Amphibian Battalion

    Science.gov (United States)

    2016-12-01

    per MarineNet course during non -drill time. Some subjects stated that they will spend a whole weekend conducting annual GMT requirements. 58 SNCOs...contends with to accomplish annual general military training requirements and mission essential tasks. Currently, there are 18 annual general military...annual general military training tasks will provide commanders additional time to focus on mission- essential task training. 14. SUBJECT TERMS 4th

  13. Small particle reagent (SPR method for detection of latent fingermarks: A review

    Directory of Open Access Journals (Sweden)

    Gurvinder Singh Bumbrah

    2016-12-01

    Full Text Available Small particle reagent technique is a means to develop latent fingermarks on wet, non-porous surfaces including glass, plastic, metals and adhesive sides of tape. The method is based on the adherence of fine particles of treating solution to the oily or fatty components of latent fingermark residues. The effectiveness of technique can be improved by adding fluorescent dye in treating solution. Fluorescent small particle reagent composition not only detects faint and weak prints but it also develops latent fingermarks on multi-colored surfaces. Small particle reagent technique is convenient, efficient and cost-effective method to develop latent fingermarks on wide range of substrates of forensic importance. Standardized testing of SPR formulation is also suggested.

  14. Multiplexed imaging surface plasmon resonance (iSPR) biosensor assay for the detection of Fusarium toxins in wheat

    Science.gov (United States)

    Certain Fusarium species (F. graminearum and F. verticilloides in particular) infest grains and can produce a wide range of fungal (myco)-toxins, causing huge economic losses worldwide. A reproducible and sensitive imaging surface plasmon resonance (iSPR) assay was developed and validated for three ...

  15. Cloning, expression and structural stability of a cold-adapted ß-Galactosidase from Rahnella sp.R3

    Science.gov (United States)

    A novel gene was isolated for the first time from a psychrophilic gram-negative bacterium Rahnella sp.R3. It encoded a cold-adapted ß-galactosidase (R-ß-Gal). Recombinant R-ß-Gal was expressed in Escherichia coli BL21 (DE3), purified, and characterized. R-ß-Gal belongs to the glycosyl hydrolase fami...

  16. 'ISL pattern reserve requirements for today's spot price,' or 'how many in-place pounds are needed for a mining pattern to be profitable in today's market'

    International Nuclear Information System (INIS)

    Anthony, H.L.

    2000-01-01

    Recent uranium spot market values place additional burdens on the geologist and project manager to identify mineralized ore that will yield a profitable return on investment to the mining venture and its investors. The author reviews the various cost components that comprise the total work effort required to produce uranium via ISL methods to arrive at a suitable ore grade that will guarantee profitably. Amortization of costs based on recent expenditures for typical ISL operations are used in conjunction with wellfield development, operating and restoration costs to determine the ore value required to show a positive return on investment. (author)

  17. Empirical analysis of optimal strategic petroleum reserve in China

    International Nuclear Information System (INIS)

    Wei, Yi-Ming; Wu, Gang; Liu, Lan-Cui; Fan, Ying

    2008-01-01

    The Chinese government began to prepare for the establishment of strategic petroleum reserve in March 2004. Therefore, answering the question of what level of strategic petroleum reserve would be suitable for China's future economic development becomes essential. Using a decision tree model based on a cost function, this paper quantifies China's optimal strategic petroleum reserve for the period 2005-2020. This approach provides a methodology reference for further quantified discussion on China's SPR. Our results show that: for economic development and security of the energy supply, the strategic petroleum reserve should be the equivalent of 30-60 days of net oil import for an optimal solution, when the oil price is $ 50/bbl; with a reserve of an equivalent of 60-90 days of net oil import to have an optimal solution when oil price is $20-35/bbl. (author)

  18. Quantifying VOC emissions for the strategic petroleum reserve.

    Energy Technology Data Exchange (ETDEWEB)

    Knowlton, Robert G.; Lord, David L.

    2013-06-01

    A very important aspect of the Department of Energys (DOEs) Strategic Petroleum Reserve (SPR) program is regulatory compliance. One of the regulatory compliance issues deals with limiting the amount of volatile organic compounds (VOCs) that are emitted into the atmosphere from brine wastes when they are discharged to brine holding ponds. The US Environmental Protection Agency (USEPA) has set limits on the amount of VOCs that can be discharged to the atmosphere. Several attempts have been made to quantify the VOC emissions associated with the brine ponds going back to the late 1970s. There are potential issues associated with each of these quantification efforts. Two efforts were made to quantify VOC emissions by analyzing VOC content of brine samples obtained from wells. Efforts to measure air concentrations were mentioned in historical reports but no data have been located to confirm these assertions. A modeling effort was also performed to quantify the VOC emissions. More recently in 2011- 2013, additional brine sampling has been performed to update the VOC emissions estimate. An analysis of the statistical confidence in these results is presented here. Arguably, there are uncertainties associated with each of these efforts. The analysis herein indicates that the upper confidence limit in VOC emissions based on recent brine sampling is very close to the 0.42 ton/MMB limit used historically on the project. Refining this estimate would require considerable investment in additional sampling, analysis, and monitoring. An analysis of the VOC emissions at each site suggests that additional discharges could be made and stay within current regulatory limits.

  19. SPR Characteristics Curve and Distribution of Residual Stress in Self-Piercing Riveted Joints of Steel Sheets

    Directory of Open Access Journals (Sweden)

    Rezwanul Haque

    2017-01-01

    Full Text Available Neutron diffraction was used to describe the residual stress distributions in self-piercing riveted (SPR joints. The sheet material displayed a compressive residual stress near the joint, and the stress gradually became tensile in the sheet material far away from the joint. The stress in the rivet leg was lower in the thick joint of the softer steel sheet than in the thin joint of the harder steel sheet. This lower magnitude was attributed to the lower force gradient during the rivet flaring stage of the SPR process curve. This study shows how the residual stress results may be related to the physical occurrences that happened during joining, using the characteristics curve. The study also shows that neutron diffraction technique enabled a crack in the rivet tip to be detected which was not apparent from a cross-section.

  20. [Development of the theoretical orientation of psychotherapists. SPR Collaborative Research Network].

    Science.gov (United States)

    Ambühl, H; Orlinsky, D; Cierpka, M; Buchheim, P; Meyerberg, J; Willutzki, U

    1995-01-01

    This article explores the extent to which, and ways in which, German speaking psychotherapists modify their theoretical orientations as a function of increasing clinical experience. The data for this come from the Development of Psychotherapists Common Core Questionnaire (CCQ), an instrument designed by the SPR Collaborative Research Network to collect a broad range of information about the therapist's background, training, practice etc. Two sections ask directly about the theoretical framework used by therapists to guide their therapeutic work, using a set of scales to assess the degree to which practitioners rely on various general models (analytic/psychodynamic, behavioral, humanistic, cognitive, systems theory, other). This permits the construction of profiles of formal and content based theoretical orientation patterns. By asking the question separately about the therapist's current practice, and about their practices as beginners, it also permits an evaluation of self-assessed change. In order to amplify the meaning of the theoretical background we ask therapists to indicate the relative importance of their patients realizing each of a series of therapeutic goals. The findings show very clearly that psychotherapists are very diverse both in the formal patterns and specific contents of their therapeutic orientations, and that they tend, as a role, to integrate two or more distinct theoretical approaches in guiding their clinical work with patients. The adherence to theoretical orientations has a strong impact on the goals that therapists typically work toward with their patients. Our findings show that therapists do pursue different goals depending on which conceptual framework they rely on.

  1. Techniques and Results for Determining Window Placement and Configuration for the Small Pressurized Rover (SPR)

    Science.gov (United States)

    Thompson, Shelby; Litaker, Harry; Howard, Robert

    2009-01-01

    A natural component to driving any type of vehicle, be it Earth-based or space-based, is visibility. In its simplest form visibility is a measure of the distance at which an object can be seen. With the National Aeronautics and Space Administration s (NASA) Space Shuttle and the International Space Station (ISS), there are human factors design guidelines for windows. However, for planetary exploration related vehicles, especially land-based vehicles, relatively little has been written on the importance of windows. The goal of the current study was to devise a proper methodology and to obtain preliminary human-in-the-loop data on window placement and location for the small pressurized rover (SPR). Nine participants evaluated multiple areas along the vehicle s front "nose", while actively maneuvering through several lunar driving simulations. Subjective data was collected on seven different aspects measuring areas of necessity, frequency of views, and placement/configuration of windows using questionnaires and composite drawings. Results indicated a desire for a large horizontal field-of-view window spanning the front of the vehicle for most driving situations with slightly reduced window areas for the lower front, lower corners, and side views.

  2. Comparative study of SPR and ELISA methods based on analysis of CD166/ALCAM levels in cancer and control human sera

    Czech Academy of Sciences Publication Activity Database

    Vaisocherová, Hana; Faca, V.M.; Taylor, A. D.; Hanash, S.; Jiang, S.

    2009-01-01

    Roč. 24, č. 7 (2009), s. 2143-2148 ISSN 0956-5663 Institutional research plan: CEZ:AV0Z20670512 Keywords : SPR * ELISA * Cancer biomarkers Subject RIV: CE - Biochemistry Impact factor: 5.429, year: 2009

  3. Immobilization of flavan-3-ols onto sensor chips to study their interactions with proteins and pectins by SPR

    Energy Technology Data Exchange (ETDEWEB)

    Watrelot, Aude A., E-mail: aude.watrelot@avignon.inra.fr [INRA, UMR408 Sécurité et Qualité des Produits d’Origine Végétale, Domaine St Paul, Site Agroparc, 84914 Avignon (France); Université d’Avignon, UMR408 Sécurité et Qualité des Produits d' Origine Végétale, F-84000 Avignon (France); Tran, Dong Tien [Université de Bordeaux, Institut des Sciences Moléculaires (UMR-CNRS 5255), 351 cours de la Libération, 33405 Talence (France); Institut Européen de Chimie et Biologie (IECB), 2 rue Robert Escarpit, 33607 Pessac (France); Buffeteau, Thierry [Université de Bordeaux, Institut des Sciences Moléculaires (UMR-CNRS 5255), 351 cours de la Libération, 33405 Talence (France); Deffieux, Denis [Université de Bordeaux, Institut des Sciences Moléculaires (UMR-CNRS 5255), 351 cours de la Libération, 33405 Talence (France); Institut Européen de Chimie et Biologie (IECB), 2 rue Robert Escarpit, 33607 Pessac (France); and others

    2016-05-15

    Highlights: • Flavanol-macromolecule interactions were determined using SPR. • Flavanols were chemically modified with a linker bearing a thiol group. • Flavanols were immobilized onto a carboxymethyl dextran surface. • Citrus pectin interacted more with flavanols than apple pectin. • Epicatechin interacted more with BSA than flavanol oligomer. - Abstract: Interactions between plant polyphenols and biomacromolecules such as proteins and pectins have been studied by several methods in solution (e.g. isothermal titration calorimetry, dynamic light scattering, nuclear magnetic resonance and spectrophotometry). Herein, these interactions were investigated in real time by Surface Plasmon Resonance (SPR) analysis after immobilization of flavan-3-ols onto a sensor chip surface. (−)-epicatechin, (+)-catechin and flavan-3-ol oligomers with an average degree of polymerization of 2 and 8 were chemically modified using N-(2-(tritylthio)ethyl)propiolamide in order to introduce a spacer unit onto the catecholic B ring. Modified flavan-3-ols were then immobilized onto a carboxymethylated dextran surface (CM5). Immobilization was validated and further verified by evaluating flavan-3-ol interaction with bovine serum albumin (BSA), poly-L-proline or commercial pectins. BSA was found to have a stronger association with monomeric flavan-3-ols than oligomers. SPR analysis of selected flavan-3-ols immobilized onto CM5 sensor chips showed a stronger association for citrus pectins than apple pectins, regardless of flavan-3-ol degree of polymerization.

  4. Immobilization of flavan-3-ols onto sensor chips to study their interactions with proteins and pectins by SPR

    International Nuclear Information System (INIS)

    Watrelot, Aude A.; Tran, Dong Tien; Buffeteau, Thierry; Deffieux, Denis

    2016-01-01

    Highlights: • Flavanol-macromolecule interactions were determined using SPR. • Flavanols were chemically modified with a linker bearing a thiol group. • Flavanols were immobilized onto a carboxymethyl dextran surface. • Citrus pectin interacted more with flavanols than apple pectin. • Epicatechin interacted more with BSA than flavanol oligomer. - Abstract: Interactions between plant polyphenols and biomacromolecules such as proteins and pectins have been studied by several methods in solution (e.g. isothermal titration calorimetry, dynamic light scattering, nuclear magnetic resonance and spectrophotometry). Herein, these interactions were investigated in real time by Surface Plasmon Resonance (SPR) analysis after immobilization of flavan-3-ols onto a sensor chip surface. (−)-epicatechin, (+)-catechin and flavan-3-ol oligomers with an average degree of polymerization of 2 and 8 were chemically modified using N-(2-(tritylthio)ethyl)propiolamide in order to introduce a spacer unit onto the catecholic B ring. Modified flavan-3-ols were then immobilized onto a carboxymethylated dextran surface (CM5). Immobilization was validated and further verified by evaluating flavan-3-ol interaction with bovine serum albumin (BSA), poly-L-proline or commercial pectins. BSA was found to have a stronger association with monomeric flavan-3-ols than oligomers. SPR analysis of selected flavan-3-ols immobilized onto CM5 sensor chips showed a stronger association for citrus pectins than apple pectins, regardless of flavan-3-ol degree of polymerization.

  5. Study of Immobilization Procedure on Silver Nanolayers and Detection of Estrone with Diverged Beam Surface Plasmon Resonance (SPR Imaging

    Directory of Open Access Journals (Sweden)

    Ibrahim Abdulhalim

    2013-03-01

    Full Text Available An immobilization protocol was developed to attach receptors on smooth silver thin films. Dense and packed 11-mercaptoundecanoic acid (11-MUA was used to avoid uncontrolled sulfidization and harmful oxidation of silver nanolayers. N,N'-dicyclohexylcarbodiimide (DCC and N-hydroxysuccinimide (NHS were added to make the silver surfaces reactive. A comparative study was carried out with different immersion times of silver samples in 11-MUA solutions with different concentrations to find the optimum conditions for immobilization. The signals, during each step of the protocol, were analyzed with a refractometer based on the surface plasmon resonance (SPR effect and luminescence techniques. Molecular interactions at the surfaces between the probe and target at the surface nanolayer shift the SPR signal, thus indicating the presence of the substance. To demonstrate specific biosensing, rabbit anti-estrone polyclonal immunoglobulin G (IgG antibody was immobilized through a linker on 47 nm silver layer deposited on SF11 glass. At the final stage, the representative endocrine disruptor—estrone—was attached and detected in deionized water with a diverging beam SPR imaging sensor.

  6. SPR-based plastic optical fibre biosensor for the detection of C-reactive protein in serum.

    Science.gov (United States)

    Aray, Ayda; Chiavaioli, Francesco; Arjmand, Mojtaba; Trono, Cosimo; Tombelli, Sara; Giannetti, Ambra; Cennamo, Nunzio; Soltanolkotabi, Mahmood; Zeni, Luigi; Baldini, Francesco

    2016-10-01

    A plastic optical fibre biosensor based on surface plasmon resonance for the detection of C-reactive protein (CRP) in serum is proposed. The biosensor was integrated into a home-made thermo-stabilized microfluidic system that allows avoiding any thermal and/or mechanical fluctuation and maintaining the best stable conditions during the measurements. A working range of 0.006-70 mg L -1 and a limit of detection of 0.009 mg L -1 were achieved. These results are among the best compared to other SPR-based biosensors for CRP detection, especially considering that they were achieved in a real and complex medium, i.e. serum. In addition, since the sensor performances satisfy those requested in physiologically-relevant clinical applications, the whole biosensing platform could well address high sensitive, easy to realize, real-time, label-free, portable and low cost diagnosis of CRP for future lab-on-a-chip applications. 3D sketch (left) of the thermo-stabilized home-made flow cell developed to house the SPR-based plastic optical fibre biosensor. Exemplary response curve (shift of the SPR wavelength versus time) of the proposed biosensor (right) for the detection of C-reactive protein in serum. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Aplicações de QCM, EIS e SPR na investigação de superfícies e interfaces para o desenvolvimento de (biosensores

    Directory of Open Access Journals (Sweden)

    Damos Flavio Santos

    2004-01-01

    Full Text Available The use of the quartz crystal microbalance process, electrochemical impedance spectroscopy and surface plasmon resonance for characterizing thin films and monitoring interfaces is presented. The theorical aspects of QCM, EIS and SPR are introduced and the main application areas are outlined. Future prospects of the combined applications of QCM, EIS and SPR methods in the studies of interfacial processes at surfaces are also discussed.

  8. Enhancement of chitosan-graphene oxide SPR sensor with a multi-metallic layers of Au–Ag–Au nanostructure for lead(II) ion detection

    Energy Technology Data Exchange (ETDEWEB)

    Kamaruddin, Nur Hasiba [Department of Electric, Electronic and Systems Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor (Malaysia); Bakar, Ahmad Ashrif A., E-mail: ashrif@ukm.edu.my [Department of Electric, Electronic and Systems Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor (Malaysia); Yaacob, Mohd Hanif; Mahdi, Mohd Adzir [Wireless and Photonic Network Research Centre, Faculty of Engineering, Universiti Putra Malaysia, 43400 Serdang, Selangor (Malaysia); Zan, Mohd Saiful Dzulkefly [Department of Electric, Electronic and Systems Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor (Malaysia); Shaari, Sahbudin [Institute of Microengineering and Nanoelectronics, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor (Malaysia)

    2016-01-15

    Highlights: • Tri-metallic Au–Ag–Au CS-GO SPR sensor was fabricated for the first time. • The tri-metallic nanostructure provided an enhanced evanescent field. • Successful functionalization of the CS-GO sensing layer. • Superior performance for lead(II) ion detection. - Abstract: We demonstrate the enhancement of surface plasmon resonance (SPR) technique by implementing a multi-metallic layers of Au–Ag–Au nanostructure in the chitosan-graphene oxide (CS-GO) SPR sensor for lead(II) ion detection. The performance of the sensor is analyzed via SPR measurements, from which the sensitivity, signal-to-noise ratio and repeatability are determined. The nanostructure layers are characterized using field emission scanning electron microscopy (FESEM), atomic force microscopy (AFM), X-ray diffraction (XRD), Raman spectroscopy and X-ray photoelectron spectroscopy (XPS). We showed that the proposed structure has increased the shift in the SPR angle up to 3.5° within the range of 0.1–1 ppm due to the enhanced evanescent field at the sensing layer-analyte interface. This sensor also exhibits great repeatability which benefits from the stable multi-metallic nanostructure. The SNR value of 0.92 for 5 ppm lead(II) ion solution and reasonable linearity range up to that concentration shows that the tri-metallic CS-GO SPR sensor gives a good response towards the lead(II) ion solution. The CS-GO SPR sensor is also sensitive to at least a 10{sup −5} change in the refractive index. The results prove that our proposed tri-metallic CS-GO SPR sensor demonstrates a strong performance and reliability for lead(II) ion detection in accordance with the standardized lead safety level for wastewater.

  9. Implementation of a SPR immunosensor for the simultaneous detection of the 22K and 20K hGH isoforms in human serum samples.

    Science.gov (United States)

    de Juan-Franco, Elena; Rodríguez-Frade, J M; Mellado, M; Lechuga, Laura M

    2013-09-30

    We have implemented a Surface Plasmon Resonance (SPR) immunosensor based on a sandwich assay for the simultaneous detection of the two main hGH isoforms, of 22 kDa (22K) and 20 kDa (20K). An oriented-antibody sensor surface specific for both hormone isoforms was assembled by using the biotin-streptavidin system. The immunosensor functionality was checked for the direct detection of the 22K hGH isoform in buffer, which gave high specificity and reproducibility (intra and inter-assay mean coefficients of variation of 8.23% and 9% respectively). The selective determination of the 22K and 20K hGH isoforms in human serum samples in a single assay was possible by using two specific anti-hGH monoclonal antibodies. The detection limit for both hormone isoforms was 0.9 ng mL(-1) and the mean coefficient of variation was below 7.2%. The excellent reproducibility and sensitivity obtained indicate the high performance of this immunosensor for implementing an anti-doping test. Copyright © 2013 Elsevier B.V. All rights reserved.

  10. Environmental Assessment for decommissioning the Strategic Petroleum Reserve Weeks Island Facility, Iberia Parish, Louisiana

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-01

    The Strategic Petroleum Reserve (SPR) Weeks Island site is one of five underground salt dome crude oils storage facilities operated by the Department of Energy (DOE). It is located in Iberia Parish, Louisiana. The purpose of the proposed action is to decommission the Weeks Island crude oil storage after the oil inventory has been transferred to other SPR facilities. Water intrusion into the salt dome storage chambers and the development of two sinkholes located near the aboveground facilities has created uncertain geophysical conditions. This Environmental Assessment describes the proposed decommissioning operation, its alternatives, and potential environmental impacts. Based on this analyses, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) and has issued the Finding of No Significant Impact (FONSI).

  11. Environmental Assessment for decommissioning the Strategic Petroleum Reserve Weeks Island Facility, Iberia Parish, Louisiana

    International Nuclear Information System (INIS)

    1995-12-01

    The Strategic Petroleum Reserve (SPR) Weeks Island site is one of five underground salt dome crude oils storage facilities operated by the Department of Energy (DOE). It is located in Iberia Parish, Louisiana. The purpose of the proposed action is to decommission the Weeks Island crude oil storage after the oil inventory has been transferred to other SPR facilities. Water intrusion into the salt dome storage chambers and the development of two sinkholes located near the aboveground facilities has created uncertain geophysical conditions. This Environmental Assessment describes the proposed decommissioning operation, its alternatives, and potential environmental impacts. Based on this analyses, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) and has issued the Finding of No Significant Impact (FONSI)

  12. Synthesis of surface plasmon resonance (SPR) triggered Ag/TiO2 photocatalyst for degradation of endocrine disturbing compounds

    International Nuclear Information System (INIS)

    Leong, Kah Hon; Gan, Bee Ling; Ibrahim, Shaliza; Saravanan, Pichiah

    2014-01-01

    Graphical abstract: - Highlights: • Ag/TiO 2 was synthesized with aid of natural photon stimulated photoreduction. • Deposited Ag prompted well the LSPRs, Schottky barrier for visible light utilization. • Photocatalytic activity was evaluated by degrading EDCs under visible light. • 3.0 wt% Ag/TiO 2 resulted with good photocatalytic efficiency over others. - Abstract: Surface deposition of silver nanoparticles (Ag NPs) onto the 100% anatase titania (Ag/TiO 2 ) for evolution of surface plasmon resonance (SPR) was achieved sustainably with the assistance of solar energy. The preparation resulted in Ag/TiO 2 photocatalyst with varied Ag depositions (0.5 wt%, 1.0 wt%, 3.0 wt% and 5.0 wt%). All obtained photocatalysts were characterized for the evolution of SPR via crystalline phase analysis, morphology, lattice fringes, surface area and pore size characteristics, chemical composition with chemical and electronic state, Raman scattering, optical and photoluminescence properties. The deposition of synthesized Ag NPs exhibited high uniformity and homogeneity and laid pathway for effective utilization of the visible region of electromagnetic spectrum through SPR. The depositions also lead for suppressing recombination rates of electron–hole. The photocatalytic evaluation was carried out by adopting two different class of endocrine disturbing compound (EDC) i.e., amoxicillin (pharmaceutical) and 2,4-dichlorophenol (pesticide) excited with artificial visible light source. Ag/TiO 2 with Ag > 0.5 wt% exhibited significant degradation efficiency for both amoxicillin and 2,4-dichlorophenol. Thus synthesized Ag/TiO 2 revealed the implication of plasmonics on TiO 2 for the enhanced visible light photocatalytic activity

  13. Synthesis of surface plasmon resonance (SPR) triggered Ag/TiO{sub 2} photocatalyst for degradation of endocrine disturbing compounds

    Energy Technology Data Exchange (ETDEWEB)

    Leong, Kah Hon; Gan, Bee Ling; Ibrahim, Shaliza [Environmental Engineering Laboratory, Department of Civil Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur (Malaysia); Saravanan, Pichiah, E-mail: saravananpichiah@um.edu.my [Environmental Engineering Laboratory, Department of Civil Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur (Malaysia); Nanotechnology and Catalysis Research Center (NANOCAT), University of Malaya, 50603 Kuala Lumpur (Malaysia)

    2014-11-15

    Graphical abstract: - Highlights: • Ag/TiO{sub 2} was synthesized with aid of natural photon stimulated photoreduction. • Deposited Ag prompted well the LSPRs, Schottky barrier for visible light utilization. • Photocatalytic activity was evaluated by degrading EDCs under visible light. • 3.0 wt% Ag/TiO{sub 2} resulted with good photocatalytic efficiency over others. - Abstract: Surface deposition of silver nanoparticles (Ag NPs) onto the 100% anatase titania (Ag/TiO{sub 2}) for evolution of surface plasmon resonance (SPR) was achieved sustainably with the assistance of solar energy. The preparation resulted in Ag/TiO{sub 2} photocatalyst with varied Ag depositions (0.5 wt%, 1.0 wt%, 3.0 wt% and 5.0 wt%). All obtained photocatalysts were characterized for the evolution of SPR via crystalline phase analysis, morphology, lattice fringes, surface area and pore size characteristics, chemical composition with chemical and electronic state, Raman scattering, optical and photoluminescence properties. The deposition of synthesized Ag NPs exhibited high uniformity and homogeneity and laid pathway for effective utilization of the visible region of electromagnetic spectrum through SPR. The depositions also lead for suppressing recombination rates of electron–hole. The photocatalytic evaluation was carried out by adopting two different class of endocrine disturbing compound (EDC) i.e., amoxicillin (pharmaceutical) and 2,4-dichlorophenol (pesticide) excited with artificial visible light source. Ag/TiO{sub 2} with Ag > 0.5 wt% exhibited significant degradation efficiency for both amoxicillin and 2,4-dichlorophenol. Thus synthesized Ag/TiO{sub 2} revealed the implication of plasmonics on TiO{sub 2} for the enhanced visible light photocatalytic activity.

  14. Reforma veřejné správy: analýza Strategie realizace Smart Administration

    OpenAIRE

    Hurychová, Tereza

    2016-01-01

    This diploma thesis is mainly to explain the significance of the document Efektivní veřejná správa a přátelské služby: Strategie realizace Smart Administration 2007 - 2015 2015 (Efficient public administration and friendly service: Smart Administration Strategy 2007 - 2015) in the context of the reform process of public administration in the Czech republic. The author′s point of view is based of the theory of change, strategic managment and modern managment methods in public administration. A...

  15. SPR Characteristics Curve and Distribution of Residual Stress in Self-Piercing Riveted Joints of Steel Sheets

    OpenAIRE

    Haque, Rezwanul; Wong, Yat C.; Paradowska, Anna; Blacket, Stuart; Durandet, Yvonne

    2017-01-01

    Neutron diffraction was used to describe the residual stress distributions in self-piercing riveted (SPR) joints. The sheet material displayed a compressive residual stress near the joint, and the stress gradually became tensile in the sheet material far away from the joint. The stress in the rivet leg was lower in the thick joint of the softer steel sheet than in the thin joint of the harder steel sheet. This lower magnitude was attributed to the lower force gradient during the rivet flaring...

  16. Lithium reserves and resources

    International Nuclear Information System (INIS)

    Evans, R.K.

    1978-01-01

    As a result of accelerating research efforts in the fields of secondary batteries and thermonuclear power generation, concern has been expressed in certain quarters regarding the availability, in sufficient quantities, of lithium. As part of a recent study by the National Research Council on behalf of the Energy Research and Development Administration, a subpanel was formed to consider the outlook for lithium. Principal areas of concern were reserves, resources and the 'surplus' available for energy applications after allowing for the growth in current lithium applications. Reserves and resources were categorized into four classes ranging from fully proved reserves to resources which are probably dependent upon the marketing of co-products to become economically attractive. Because of the proprietary nature of data on beneficiation and processing recoveries, the tonnages of available lithium are expressed in terms of plant feed. However, highly conservative assumptions have been made concerning mining recoveries and these go a considerable way to accounting for total losses. Western World reserves and resources of all classes are estimated at 10.6 million tonnes Li of which 3.5 million tonnes Li are located in the United States. Current United States capacity, virtually equivalent to Western World capacity, is 4700 tonnes Li and production in 1976 approximated to 3500 tonnes Li. Production for current applications is expected to grow to approx. 10,000 tonnes in year 2000 and 13,000 tonnes a decade later. The massive excess of reserves and resources over that necessary to support conventional requirements has limited the amount of justifiable exploration expenditures; on the last occasion, there was a a major increase in demand (by the USAEA) reserves and capacity were increased rapidly. There are no foreseeable reasons why this shouldn't happen again when the need is clear. (author)

  17. Qualitative and Quantitative Detection of PrPSc Based on the Controlled Release Property of Magnetic Microspheres Using Surface Plasmon Resonance (SPR

    Directory of Open Access Journals (Sweden)

    Zhichao Lou

    2018-02-01

    Full Text Available Prion protein (PrPSc has drawn widespread attention due to its pathological potential to prion diseases. In this work, we constructed a novel surface plasmon resonance (SPR detection assay involving magnetic microspheres (MMs and its controlled release property, for selective capture, embedding, concentration, and SPR detection of PrPSc with high sensitivity and specificity. Aptamer-modified magnetic particles (AMNPs were used to specifically capture PrPSc. Amphiphilic copolymer was used to embed the labeled PrPSc and form magnetic microspheres to isolate PrPSc from the external environment. Static magnetic and alternating magnetic fields were used to concentrate and control release the embedded PrPSc, respectively. Finally, the released AMNPs-labeled PrPSc was detected by SPR which was equipped with a bare gold sensing film. A good linear relationship was obtained between SPR responses and the logarithm of PrPSc concentrations over a range of 0.01–1000 ng/mL. The detection sensitivity for PrPSc was improved by 10 fold compared with SPR direct detection format. The specificity of the present biosensor was also determined by PrPC and other reagents as controls. This proposed approach could also be used to isolate and detect other highly pathogenic biomolecules with similar structural characteristics by altering the corresponding aptamer in the AMNPs conjugates.

  18. Geomechanical testing of Bayou Choctaw 102B core for SPR analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ingraham, Mathew Duffy; Broome, Scott Thomas; Bauer, Stephen J.; Barrow, Perry Carl; Flint, Gregory Mark.

    2014-02-01

    A laboratory testing program was developed to examine the short-term mechanical and time-dependent (creep) behavior of salt from the Bayou Choctaw Salt Dome. This report documents the test methodologies, and constitutive properties inferred from tests performed. These are used to extend our understanding of the mechanical behavior of the Bayou Choctaw domal salt and provide a data set for numerical analyses. The resulting information will be used to support numerical analyses of the current state of the Bayou Choctaw Dome as it relates to its crude oil storage function as part of the US Strategic Petroleum Reserve. Core obtained from Drill Hole BC-102B was tested under creep and quasi-static constant mean stress axisymmetric compression, and constant mean stress axisymmetric extension conditions. Creep tests were performed at 100 degrees Fahrenheit, and the axisymmetric tests were performed at ambient temperatures (72-78 degrees Fahrenheit). The testing performed indicates that the dilation criterion is pressure and stress state dependent. It was found that as the mean stress increases, the shear stress required to cause dilation increases. The results for this salt are reasonably consistent with those observed for other domal salts. Also it was observed that tests performed under extensile conditions required consistently lower shear stress to cause dilation for the same mean stress, which is consistent with other domal salts. Young's moduli ranged from 3.95 x 106 to 8.51 x 106 psi with an average of 6.44 x 106 psi, with Poisson's ratios ranging from 0.10 to 0.43 with an average of 0.30. Creep testing indicates that the BC salt is intermediate in creep resistance when compared with other bedded and domal salt steady-state behavior.

  19. Správa koncových uzlů datových sítí

    OpenAIRE

    Knol, Radek

    2012-01-01

    Tato bakalářská práce má za cíl analyzovat možnosti správy koncových uzlů datových sítí. Na základě této analýzy vznikla aplikace pro operační systémy Microsoft Windows, která má za úkol efektivně spravovat a usnadňovat správu a konfiguraci koncových prvků sítě jakými jsou počítače, servery, přepínače, rozbočovače, IP telefony, IP kamery a další zařízení. Tato aplikace umí pracovat se skupinami zařízení, umí je třídit podle zadaných kritérií a na výslednou skupinu či jednotlivé prvky umí apli...

  20. Plasma processing of the Si(0 0 1) surface for tuning SPR of Au/Si-based plasmonic nanostructures

    Energy Technology Data Exchange (ETDEWEB)

    Giangregorio, Maria M. [Institute of Inorganic Methodologies and of Plasmas, IMIP-CNR and INSTM sez. Bari, Via Orabona 4, 70125 Bari (Italy)]. E-mail: michelaria.giangregorio@ba.imip.cnr.it; Losurdo, Maria [Institute of Inorganic Methodologies and of Plasmas, IMIP-CNR and INSTM sez. Bari, Via Orabona 4, 70125 Bari (Italy); Sacchetti, Alberto [Institute of Inorganic Methodologies and of Plasmas, IMIP-CNR and INSTM sez. Bari, Via Orabona 4, 70125 Bari (Italy); Capezzuto, Pio [Institute of Inorganic Methodologies and of Plasmas, IMIP-CNR and INSTM sez. Bari, Via Orabona 4, 70125 Bari (Italy); Bruno, Giovanni [Institute of Inorganic Methodologies and of Plasmas, IMIP-CNR and INSTM sez. Bari, Via Orabona 4, 70125 Bari (Italy)

    2006-12-15

    Au nanoclusters have been deposited on Si(0 0 1) surfaces by sputtering of a metallic Au target using an Ar plasma. Different wet and dry treatments of the Si(0 0 1) surface, including dipping in HF solution and exposure to H{sub 2} and N{sub 2} plasmas, have been applied and the effects of these treatments on the Au nanoparticles/Si interface, the Au nanoclusters aspect ratio and the surface plasmon resonance (SPR) energy and amplitude are investigated exploiting spectroscopic ellipsometry and atomic force microscopy. It is found that the Au nanoclusters aspect ratio depends on the extent of the Au-Si intermixing. The thicker the Au-Si interface layer, the larger the Au nanoparticles aspect ratio and the red-shift of the SPR peak. Furthermore, SiO{sub 2} and the H{sub 2} plasma treatment inhibit the Si-Au intermixing, while HF-dipping and the N{sub 2} plasma treatment favour Au-Si intermixing, yielding silicide formation which increases the Si wetting by Au.

  1. Antibody-Hapten Recognition at the Surface of Functionalized Liposomes Studied by SPR: Steric Hindrance of Pegylated Phospholipids in Stealth Liposomes Prepared for Targeted Radionuclide Delivery

    Directory of Open Access Journals (Sweden)

    Eliot. P. Botosoa

    2011-01-01

    Full Text Available Targeted PEGylated liposomes could increase the amount of drugs or radionuclides delivered to tumor cells. They show favorable stability and pharmacokinetics, but steric hindrance of the PEG chains can block the binding of the targeting moiety. Here, specific interactions between an antihapten antibody (clone 734, specific for the DTPA-indium complex and DTPA-indium-tagged liposomes were characterized by surface plasmon resonance (SPR. Non-PEGylated liposomes fused on CM5 chips whereas PEGylated liposomes did not. By contrast, both PEGylated and non-PEGylated liposomes attached to L1 chips without fusion. SPR binding kinetics showed that, in the absence of PEG, the antibody binds the hapten at the surface of lipid bilayers with the affinity of the soluble hapten. The incorporation of PEGylated lipids hinders antibody binding to extents depending on PEGylated lipid fraction and PEG molecular weight. SPR on immobilized liposomes thus appears as a useful technique to optimize formulations of liposomes for targeted therapy.

  2. Exploiting Surface Plasmon Resonance (SPR Technology for the Identification of Fibroblast Growth Factor-2 (FGF2 Antagonists Endowed with Antiangiogenic Activity

    Directory of Open Access Journals (Sweden)

    Marco Presta

    2009-08-01

    Full Text Available Angiogenesis, the process of new blood vessel formation, is implicated in various physiological/pathological conditions, including embryonic development, inflammation and tumor growth. Fibroblast growth factor-2 (FGF2 is a heparin-binding angiogenic growth factor involved in various physiopathological processes, including tumor neovascularization. Accordingly, FGF2 is considered a target for antiangiogenic therapies. Thus, numerous natural/synthetic compounds have been tested for their capacity to bind and sequester FGF2 in the extracellular environment preventing its interaction with cellular receptors. We have exploited surface plasmon resonance (SPR technique in search for antiangiogenic FGF2 binders/antagonists. In this review we will summarize our experience in SPR-based angiogenesis research, with the aim to validate SPR as a first line screening for the identification of antiangiogenic compounds.

  3. Thailand's energy security: Strategic Petroleum Reserve and its economic impacts

    Science.gov (United States)

    Leesombatpiboon, Poonpat

    This dissertation studies Thailand's energy security from three related perspectives, the role of oil on the Thai macroeconomy, the sectoral demand for oil in Thailand, and the Strategic Petroleum Reserve (SPR) policy for the Thai economy. The first part of my dissertation estimates an error correction model of aggregate production function for Thailand. Thai economic growth is modeled as a function of labor, capital, and oil consumption. Unlike previous studies that focus on testing the causal relationship between energy consumption and economic growth, I focus on measuring the elasticity of economic growth with respect to oil consumption and oil prices. I find a cointegration relationship between GDP, capital, labor, and oil consumption. The results suggest that there exists a constant-return-to-scale characteristic in Thailand's aggregate production function with the contribution of labor, oil, and capital to output around 68, 19, and 13 percent respectively. The long-run and short-run contribution of oil consumption to the economy appears to be fairly close, suggesting that oil has a critical role in the Thai economy. In the short run, oil shortages have a much more severe impact on Thai economy than the effects of an oil price shock. For example, a 10 percent shortfall in oil consumption might cause economic growth to shrink by 2 percent within the same year while a sharp10 percent rise in oil prices canlead output growth to a fall by about 0.5 percent. The response of output to increases and decreases in oil prices is found to be asymmetric in the short run. The second part of my dissertation examines the short-run and long-run determinants of final oil consumption in seven major economic sectors in Thailand. Two different approaches are compared. The first approach uses dynamic panel data estimation techniques taking into account oil consumption of the whole economy in an aggregate manner. The second approach employs the Autoregressive Distributed Lag (ADL

  4. Interactions of doxorubicin with self-assembled monolayer-modified electrodes: electrochemical, surface plasmon resonance (SPR), and gravimetric studies.

    Science.gov (United States)

    Nieciecka, Dorota; Krysinski, Pawel

    2011-02-01

    We present the results on the partitioning of doxorubicin (DOX), a potent anticancer drug, through the model membrane system, self-assembled monolayers (SAMs) on gold electrodes. The monolayers were formed from alkanethiols of comparable length with different ω-terminal groups facing the aqueous electrolyte: the hydrophobic -CH(3) groups for the case of dodecanethiol SAMs or hydrophilic -OH groups of mercaptoundecanol SAMs. The electrochemical experiments combined with the surface plasmon resonance (SPR) and gravimetric studies show that doxorubicin is likely adsorbed onto the surface of hydrophilic monolayer, while for the case of the hydrophobic one the drug mostly penetrates the monolayer moiety. The adsorption of the drug hinders further penetration of doxorubicin into the monolayer moiety.

  5. The Huguenot identity in 19th century music: The "Sechs Sprüche zum Kirchenjahr" by Felix Mendelssohn

    Directory of Open Access Journals (Sweden)

    Robert Weeda

    2012-01-01

    Full Text Available Hierdie artikel gaan oor die komponiste Felix Mendelssohn en Giacomo Meyerbeer. Meyerbeer die komponis van die opera Les Huguenots, en Mendelssohn, 'n Jood wat 'n "Calvinis" geword het. Meyerbeer vertel in die opera (1836, geanker aan die Lutherse melodie "'n Vaste Burg is onse God" die verhaal van die Bartolomeusnagmoorde. Mendelssohn, 'n bekeerling tot die sg Hugenote-religie, verwoord sy opregte geloof gedurende die jare 1843-1846 in die voortreflike musikaleuitdrukkings Sechs Sprüche zum Kirchenjahr (Ses Spreuke vir die Kerkjaar wat opgeneem is in die gereformeerde liturgie vir die Brandenburg gemeente. Op 'n bepaalde manier vertel albei komponiste ons iets van die Hugenote-identiteit in die negentiende-eeuse musiek.

  6. An Improved Label-Free Indirect Competitive SPR Immunosensor and Its Comparison with Conventional ELISA for Ractopamine Detection in Swine Urine

    Science.gov (United States)

    Wang, Sai; Zhao, Shuai; Wei, Xiao; Zhang, Shan; Liu, Jiahui; Dong, Yiyang

    2017-01-01

    Ractopamine (RCT) is banned for use in animals in many countries, and it is urgent to develop efficient methods for specific and sensitive RCT detection. A label-free indirect competitive surface plasmon resonance (SPR) immunosensor was first developed with a primary antibody herein and then improved by a secondary antibody for the detection of RCT residue in swine urine. Meanwhile, a pre-incubation process of RCT and the primary antibody was performed to further improve the sensitivity. With all the key parameters optimized, the improved immunosenor can attain a linear range of 0.3–32 ng/mL and a limit of detection (LOD) of 0.09 ng/mL for RCT detection with high specificity. Furthermore, the improved label-free SPR immunosenor was compared thoroughly with a conventional enzyme-linked immunosorbent assay (ELISA). The SPR immunosensor showed advantages over the ELISA in terms of LOD, reagent consumption, analysis time, experiment automation, and so on. The SPR immunosensor can be used as potential method for real-time monitoring and screening of RCT residue in swine urine or other samples. In addition, the design using antibody pairs for biosensor development can be further referred to for other small molecule detection. PMID:28300766

  7. An Improved Label-Free Indirect Competitive SPR Immunosensor and Its Comparison with Conventional ELISA for Ractopamine Detection in Swine Urine

    Directory of Open Access Journals (Sweden)

    Sai Wang

    2017-03-01

    Full Text Available Ractopamine (RCT is banned for use in animals in many countries, and it is urgent to develop efficient methods for specific and sensitive RCT detection. A label-free indirect competitive surface plasmon resonance (SPR immunosensor was first developed with a primary antibody herein and then improved by a secondary antibody for the detection of RCT residue in swine urine. Meanwhile, a pre-incubation process of RCT and the primary antibody was performed to further improve the sensitivity. With all the key parameters optimized, the improved immunosenor can attain a linear range of 0.3–32 ng/mL and a limit of detection (LOD of 0.09 ng/mL for RCT detection with high specificity. Furthermore, the improved label-free SPR immunosenor was compared thoroughly with a conventional enzyme-linked immunosorbent assay (ELISA. The SPR immunosensor showed advantages over the ELISA in terms of LOD, reagent consumption, analysis time, experiment automation, and so on. The SPR immunosensor can be used as potential method for real-time monitoring and screening of RCT residue in swine urine or other samples. In addition, the design using antibody pairs for biosensor development can be further referred to for other small molecule detection.

  8. Comparison of the CPU and memory performance of StatPatternRecognitions (SPR) and Toolkit for MultiVariate Analysis (TMVA)

    International Nuclear Information System (INIS)

    Palombo, G.

    2012-01-01

    High Energy Physics data sets are often characterized by a huge number of events. Therefore, it is extremely important to use statistical packages able to efficiently analyze these unprecedented amounts of data. We compare the performance of the statistical packages StatPatternRecognition (SPR) and Toolkit for MultiVariate Analysis (TMVA). We focus on how CPU time and memory usage of the learning process scale versus data set size. As classifiers, we consider Random Forests, Boosted Decision Trees and Neural Networks only, each with specific settings. For our tests, we employ a data set widely used in the machine learning community, “Threenorm” data set, as well as data tailored for testing various edge cases. For each data set, we constantly increase its size and check CPU time and memory needed to build the classifiers implemented in SPR and TMVA. We show that SPR is often significantly faster and consumes significantly less memory. For example, the SPR implementation of Random Forest is by an order of magnitude faster and consumes an order of magnitude less memory than TMVA on Threenorm data.

  9. Environmental assessment of the brine pipeline replacement for the Strategic Petroleum Reserve Bryan Mound Facility in Brazoria County, Texas

    International Nuclear Information System (INIS)

    1993-09-01

    The Department of Energy (DOE) has prepared an environmental assessment (EA), DOE/EA-0804, for the proposed replacement of a deteriorated brine disposal pipeline from the Strategic Petroleum Reserve (SPR) Bryan Mound storage facility in Brazoria County, Texas, into the Gulf of Mexico. In addition, the ocean discharge outfall would be moved shoreward by locating the brine diffuser at the end of the pipeline 3.5 miles offshore at a minimum depth of 30 feet. The action would occur in a floodplain and wetlands; therefore, a floodplain/wetlands assessment has been prepared in conjunction with this EA. Based on the analyses in the EA, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) of 1969 (42 USC. 4321, et seg.). Therefore, the preparation of an Environmental Impact Statement (EIS) is not required, and the Department is issuing this Finding of No Significant Impact (FONSI). This FONSI also includes a Floodplain Statement of Findings in accordance with 10 CFR Part 1022

  10. Environmental assessment of the brine pipeline replacement for the Strategic Petroleum Reserve Bryan Mound Facility in Brazoria County, Texas

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The Department of Energy (DOE) has prepared an environmental assessment (EA), DOE/EA-0804, for the proposed replacement of a deteriorated brine disposal pipeline from the Strategic Petroleum Reserve (SPR) Bryan Mound storage facility in Brazoria County, Texas, into the Gulf of Mexico. In addition, the ocean discharge outfall would be moved shoreward by locating the brine diffuser at the end of the pipeline 3.5 miles offshore at a minimum depth of 30 feet. The action would occur in a floodplain and wetlands; therefore, a floodplain/wetlands assessment has been prepared in conjunction with this EA. Based on the analyses in the EA, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) of 1969 (42 USC. 4321, et seg.). Therefore, the preparation of an Environmental Impact Statement (EIS) is not required, and the Department is issuing this Finding of No Significant Impact (FONSI). This FONSI also includes a Floodplain Statement of Findings in accordance with 10 CFR Part 1022.

  11. Using QCM and SPR for the Kinetic Evaluation of the Binding Between A New Recombinant Chimeric Protein and Specific Antibodies of the Visceral Leishmaniasis.

    Science.gov (United States)

    Souto, Denio E P; Faria, Angelica R; de Andrade, Helida M; Kubota, Lauro T

    2015-01-01

    In the present study, the surface plasmon resonance (SPR) and quartz crystal microbalance (QCM) techniques were employed to kinetically evaluate the binding affinity of a new recombinant chimeric protein (CP10) toward anti-Leishmania infantum antibodies for the immunodiagnostics of the visceral leishmaniasis (VL). This chimeric protein was formed by the union in a same artificial coding DNA of ten different peptides, which showed themselves reactive toward positive canine serum for VL. Using the CP10 in enzyme-linked immunosorbent assays (ELISA), it was possible to detect 80% of the asymptomatic infected dogs. After this, SPR and QCM immunosensors were constructed by the covalent immobilization of the CP10 on a self-assembled monolayer (SAM) formed by adsorption of alkanethiol on gold substrates. The thickness (6.80 nm) and the refractive index (1.475) of the protein on the SAM were simultaneously determined through SPR curves measured in different wavelengths (670 and 785 nm). Interactions between the CP10 and its specific IgGs (anti-CP10 antibodies) were characterized by the electrochemical impedance spectroscopy, SPR and QCM techniques. The equilibrium dissociation constant obtained by SPR (K(D) = 8.27 x 10(-10) mol.L(-1)) and QCM (K(D) = 2.42 x 10(- 10) mol.L(-1)) demonstrated high binding affinity of the CP10 toward anti-CP10 antibodies. In this sense, this work quantitatively proves the strong antigenic character of a new recombinant chimeric protein, giving evidence to potential contribution for the use of this protein in programs of control of the VL.

  12. Cognitive reserve in aging.

    Science.gov (United States)

    Tucker, A M; Stern, Y

    2011-06-01

    Cognitive reserve explains why those with higher IQ, education, occupational attainment, or participation in leisure activities evidence less severe clinical or cognitive changes in the presence of age-related or Alzheimer's disease pathology. Specifically, the cognitive reserve hypothesis is that individual differences in how tasks are processed provide reserve against brain pathology. Cognitive reserve may allow for more flexible strategy usage, an ability thought to be captured by executive functions tasks. Additionally, cognitive reserve allows individuals greater neural efficiency, greater neural capacity, and the ability for compensation via the recruitment of additional brain regions. Taking cognitive reserve into account may allow for earlier detection and better characterization of age-related cognitive changes and Alzheimer's disease. Importantly, cognitive reserve is not fixed but continues to evolve across the lifespan. Thus, even late-stage interventions hold promise to boost cognitive reserve and thus reduce the prevalence of Alzheimer's disease and other age-related problems.

  13. Solution NMR structure of the NlpC/P60 domain of lipoprotein Spr from Escherichia coli: structural evidence for a novel cysteine peptidase catalytic triad.

    Science.gov (United States)

    Aramini, James M; Rossi, Paolo; Huang, Yuanpeng J; Zhao, Li; Jiang, Mei; Maglaqui, Melissa; Xiao, Rong; Locke, Jessica; Nair, Rajesh; Rost, Burkhard; Acton, Thomas B; Inouye, Masayori; Montelione, Gaetano T

    2008-09-16

    Escherichia coli Spr is a membrane-anchored cell wall hydrolase. The solution NMR structure of the C-terminal NlpC/P60 domain of E. coli Spr described here reveals that the protein adopts a papain-like alpha+beta fold and identifies a substrate-binding cleft featuring several highly conserved residues. The active site features a novel Cys-His-His catalytic triad that appears to be a unique structural signature of this cysteine peptidase family. Moreover, the relative orientation of these catalytic residues is similar to that observed in the analogous Ser-His-His triad, a variant of the classic Ser-His-Asp charge relay system, suggesting the convergent evolution of a catalytic mechanism in quite distinct peptidase families.

  14. Fabrication and Characterization of a SPR Based Fiber Optic Sensor for the Detection of Chlorine Gas Using Silver and Zinc Oxide

    Directory of Open Access Journals (Sweden)

    Sruthi P. Usha

    2015-04-01

    Full Text Available A fiber optic chlorine gas sensor working on surface plasmon resonance (SPR technique fabricated using coatings of silver and zinc oxide films over unclad core of the optical fiber is reported. The sensor probe is characterized using wavelength interrogation and recording SPR spectra for different concentrations of chlorine gas around the probe. A red shift is observed in the resonance wavelength on increasing the concentration of the chlorine gas. The thickness of the zinc oxide film is optimized to achieve the maximum sensitivity of the sensor. In addition to wavelength interrogation, the sensor can also work on intensity modulation. The selectivity of the sensor towards chlorine gas is verified by carrying out measurements for different gases. The sensor has various advantages such as better sensitivity, good selectivity, reusability, fast response, low cost, capability of online monitoring and remote sensing.

  15. Measuring Ultra-low Levels of Nucleotide Biomarkers Using Quartz Crystal Microbalance and SPR Microarray Imaging Methods: A Comparative Analysis.

    Science.gov (United States)

    Premaratne, Gayan; Al Mubarak, Zainab H; Senavirathna, Lakmini; Liu, Lin; Krishnan, Sadagopan

    2017-12-01

    Circulating serum nucleotide biomarkers are useful indicators for early diagnosis of cancer, respiratory illnesses, and other deadly diseases. In this work, we compared detection performances of a quartz crystal microbalance (QCM), which is a mass sensor, with that of a surface plasmon resonance (SPR) microarray for an oligonucleotide mimic of a microRNA-21 biomarker. A surface immobilized capture oligonucleotide probe was used to hybridize with the target oligonucleotide (i.e., the microRNA-21 mimic) to facilitate selective detection. To obtain ultra-low femtomolar (fM) detection sensitivity, gold nanoparticles (50 nm) were conjugated with the target oligonucleotide. We achieved detection limits of 28and 47 fM for the target oligonucleotide by the QCM and SPRi microarray, respectively. We also conducted sample recovery studies and performed matrix effect analysis. Although the QCM had a lower detection limit, the microarray approach offered better throughput for analysis of up to 16 samples. We confirmed that the designed assay was selective for the target oligonucleotide and did not show signals for the control oligonucleotide with five mismatch sites relative to the target sequence. Combination of the QCM and microarray methods that utilize the same assay chemistry on gold are useful for overcoming clinical sample matrix effects and achieving ultra-low detection of small nucleotide biomarkers with quantitative insights.

  16. Zabezpečená správa síťových klientů

    OpenAIRE

    Lojek, Stanislav

    2016-01-01

    Tato práce se zaměřuje na centralizovanou správu síťových klientů pomocí operačního systému Windows server 2012 a jeho funkcí. Zahrnuje vytvoření automatizované instalace s jednotnou konfigurací operačního systému Windows. Součástí je i implementace služeb a funkcí nezbytných pro jeho bezproblémové zprovoznění. Hlavní část práce je věnovaná nasazení softwaru pomocí GPO politik a instalačních MSI balíčků. Také je zde popsána možnost nasazení pomocí Windows PowerShell skriptu. This work focu...

  17. Integrating nanohybrid membranes of reduced graphene oxide: chitosan: silica sol gel with fiber optic SPR for caffeine detection

    Science.gov (United States)

    Kant, Ravi; Tabassum, Rana; Gupta, Banshi D.

    2017-05-01

    Caffeine is the most popular psychoactive drug consumed in the world for improving alertness and enhancing wakefulness. However, caffeine consumption beyond limits can result in lot of physiological complications in human beings. In this work, we report a novel detection scheme for caffeine integrating nanohybrid membranes of reduced graphene oxide (rGO) in chitosan modified silica sol gel (rGO: chitosan: silica sol gel) with fiber optic surface plasmon resonance. The chemically synthesized nanohybrid membrane forming the sensing route has been dip coated over silver coated unclad central portion of an optical fiber. The sensor works on the mechanism of modification of dielectric function of sensing layer on exposure to analyte solution which is manifested in terms of red shift in resonance wavelength. The concentration of rGO in polymer network of chitosan and silica sol gel and dipping time of the silver coated probe in the solution of nanohybrid membrane have been optimized to extricate the supreme performance of the sensor. The optimized sensing probe possesses a reasonably good sensitivity and follows an exponentially declining trend within the entire investigating range of caffeine concentration. The sensor boasts of an unparalleled limit of detection value of 1.994 nM and works well in concentration range of 0-500 nM with a response time of 16 s. The impeccable sensor methodology adopted in this work combining fiber optic SPR with nanotechnology furnishes a novel perspective for caffeine determination in commercial foodstuffs and biological fluids.

  18. Construction and modeling of concatemeric DNA multilayers on a planar surface as monitored by QCM-D and SPR.

    Science.gov (United States)

    Sun, Lu; Svedhem, Sofia; Akerman, Björn

    2014-07-22

    The sequential hybridization of a 534 base pair DNA concatemer layer was monitored by QCM-D and SPR, and the QCM-D data were analyzed by Voigt viscoelastic models. The results show that Voigt-based modeling gives a good description of the experimental data but only if shear viscosity and elasticity are allowed to depend on the shear frequency. The derived layer thickness, shear viscosity and elasticity of the growing film give a representation of the DNA film in agreement with known bulk properties of DNA, and reveal a maximum in film viscosity when the molecules in the layer contain 75 base pairs. The experimental data during construction of a 3084 bp DNA concatemer layer were compared to predictions of the QCM-D response of a 1 μm thick film of rod-like polymers. A predicted nonmonotonous variation of dissipation with frequency (added mass) is in qualitative agreement with the experiments, but with a quantitative disagreement which likely reflects that the flexibility of such long DNA molecules is not included in the model.

  19. Adsorption of dianionic surfactants based on amino acids at different surfaces studied by QCM-D and SPR.

    Science.gov (United States)

    Bordes, Romain; Tropsch, Jürgen; Holmberg, Krister

    2010-07-06

    The adsorption of three dicarboxylic amino acid-based surfactants, disodium N-lauroylaminomalonate, disodium N-lauroylaspartate, and disodium N-lauroylglutamate, has been studied by surface plasmon resonance (SPR) and the quartz crystal microbalance with dissipation monitoring (QCM-D). These surfactants have high cmc values, which means that the unimer concentration is high at the plateau value of adsorption. This gives rise to a considerable "bulk effect", which must be deducted from the observed value in order to obtain the true value of the adsorbed amount. In this article, we show how this can be done for the QCM-D technique. Adsorption is studied on silica, gold, gold hydrophobized by a self-assembled layer of an alkane thiol, and hydroxyapatite. Adsorption on hydroxyapatite differs very much among the three surfactants, with the aspartate derivative giving the strongest and the glutamate giving the weakest adsorption. This difference is explained as the difference in ability of the dicarboxylic amphiphiles to chelate calcium in the crystal lattice.

  20. Integrating nanohybrid membranes of reduced graphene oxide: chitosan: silica sol gel with fiber optic SPR for caffeine detection.

    Science.gov (United States)

    Kant, Ravi; Tabassum, Rana; Gupta, Banshi D

    2017-05-12

    Caffeine is the most popular psychoactive drug consumed in the world for improving alertness and enhancing wakefulness. However, caffeine consumption beyond limits can result in lot of physiological complications in human beings. In this work, we report a novel detection scheme for caffeine integrating nanohybrid membranes of reduced graphene oxide (rGO) in chitosan modified silica sol gel (rGO: chitosan: silica sol gel) with fiber optic surface plasmon resonance. The chemically synthesized nanohybrid membrane forming the sensing route has been dip coated over silver coated unclad central portion of an optical fiber. The sensor works on the mechanism of modification of dielectric function of sensing layer on exposure to analyte solution which is manifested in terms of red shift in resonance wavelength. The concentration of rGO in polymer network of chitosan and silica sol gel and dipping time of the silver coated probe in the solution of nanohybrid membrane have been optimized to extricate the supreme performance of the sensor. The optimized sensing probe possesses a reasonably good sensitivity and follows an exponentially declining trend within the entire investigating range of caffeine concentration. The sensor boasts of an unparalleled limit of detection value of 1.994 nM and works well in concentration range of 0-500 nM with a response time of 16 s. The impeccable sensor methodology adopted in this work combining fiber optic SPR with nanotechnology furnishes a novel perspective for caffeine determination in commercial foodstuffs and biological fluids.

  1. HAHA--nothing to laugh about. Measuring the immunogenicity (human anti-human antibody response) induced by humanized monoclonal antibodies applying ELISA and SPR technology.

    Science.gov (United States)

    Nechansky, Andreas

    2010-01-05

    Immunogenicity induced by passively applied proteins is a serious issue because it is directly related to the patient's safety. The out-come of an immune reaction to a therapeutic protein can range from transient appearance of antibodies without any clinical significance to severe life threatening conditions. Within this article, enzyme-linked immunosorbent assay (ELISA) and surface plasmon resonance (SPR) methodology to measure immunogenicity are compared and the pros and cons are discussed.

  2. Ekonomie a správa životního prostředí – informace o novém magisterském oboru

    Directory of Open Access Journals (Sweden)

    Petr Šauer

    2007-08-01

    Full Text Available Text představuje nový navazující magisterský studijní obor Ekonomie a správa životního prostředí, který byl otevřen na Národohospodářské fakultě Vysoké školy ekonomické v Praze.

  3. An Advanced Semimetal-Organic Bi Spheres-g-C3N4 Nanohybrid with SPR-Enhanced Visible-Light Photocatalytic Performance for NO Purification.

    Science.gov (United States)

    Dong, Fan; Zhao, Zaiwang; Sun, Yanjuan; Zhang, Yuxin; Yan, Shuai; Wu, Zhongbiao

    2015-10-20

    To achieve efficient photocatalytic air purification, we constructed an advanced semimetal-organic Bi spheres-g-C3N4 nanohybrid through the in-situ growth of Bi nanospheres on g-C3N4 nanosheets. This Bi-g-C3N4 compound exhibited an exceptionally high and stable visible-light photocatalytic performance for NO removal due to the surface plasmon resonance (SPR) endowed by Bi metal. The SPR property of Bi could conspicuously enhance the visible-light harvesting and the charge separation. The electromagnetic field distribution of Bi spheres involving SPR effect was simulated and reaches its maximum in close proximity to the Bi particle surface. When the Bi metal content was controlled at 25%, the corresponding Bi-g-C3N4 displayed outstanding photocatalytic capability and transcended those of other visible-light photocatalysts. The Bi-g-C3N4 exhibited a high structural stability under repeated photocatalytic runs. A new visible-light-induced SPR-based photocatalysis mechanism with Bi-g-C3N4 was proposed on the basis of the DMPO-ESR spin-trapping. The photoinduced electrons could transfer from g-C3N4 to the Bi metal, as revealed with time-resolved fluorescence spectra. The function of Bi semimetal as a plasmonic cocatalyst for boosting visible light photocatalysis was similar to that of noble metals, which demonstrated a great potential of utilizing the economically feasible Bi element as a substitute for noble metals for the advancement of photocatalysis efficiency.

  4. Construction of hexahedral elements mesh capturing realistic geometries of Bayou Choctaw SPR site

    Energy Technology Data Exchange (ETDEWEB)

    Park, Byoung Yoon [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Roberts, Barry L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    The three-dimensional finite element mesh capturing realistic geometries of Bayou Choctaw site has been constructed using the sonar and seismic survey data obtained from the field. The mesh is consisting of hexahedral elements because the salt constitutive model is coded using hexahedral elements. Various ideas and techniques to construct finite element mesh capturing artificially and naturally formed geometries are provided. The techniques to reduce the number of elements as much as possible to save on computer run time with maintaining the computational accuracy is also introduced. The steps and methodologies could be applied to construct the meshes of Big Hill, Bryan Mound, and West Hackberry strategic petroleum reserve sites. The methodology could be applied to the complicated shape masses for not only various civil and geological structures but also biological applications such as artificial limbs.

  5. Övergående eller bestående? : En uppföljningsstudie av 15-18åringar med språkstörning i förskoleåldern

    OpenAIRE

    Löfstedt, Annika; Nilsson, Charlotta

    2005-01-01

    I logopediskt arbete med förskolebarn med språkstörning är kunskap om hur den språkliga utvecklingen fortskrider mycket väsentlig. Är svårigheterna av övergående karaktär eller blir de bestående i något avseende? Kännedom om vilka konsekvenser språkstörning får i ett längre perspektiv och vilka språkliga faktorer som samverkar behövs bland annat för att tidigt kunna sätta in rätt åtgärder och senare tillgodose behovet av stöd i skolan. Syftet med undersökningen är att närmare beskriva hur bar...

  6. Simultaneous Detection of Escherichia coli O157:H7, Salmonella enteritidis, and Listeria monocytogenes at a Very Low Level Using Simultaneous Enrichment Broth and Multichannel SPR Biosensor.

    Science.gov (United States)

    Zhang, Xiaoguang; Tsuji, Sachiko; Kitaoka, Hayato; Kobayashi, Hiroshi; Tamai, Mitsuru; Honjoh, Ken-Ichi; Miyamoto, Takahisa

    2017-10-01

    Detection of foodborne pathogens at very low levels is still a challenge. A custom-built multichannel surface plasmon resonance (SPR) biosensor and simultaneous enrichment broth (SEB) were used to develop a simultaneous detection method for 3 important foodborne pathogens, Escherichia coli O157:H7 (O157:H7), Salmonella enteritidis, and Listeria monocytogenes, at a very low level. These 3 foodborne pathogens at a very low level (14, 6, and 28 CFU/25 g (mL) for O157:H7, S. enteritidis, and L. monocytogenes, respectively) were inoculated in SEB and incubated at 37 ˚C for 24 h. Sample prepared from the simultaneous enrichment culture was analyzed using the multichannel SPR biosensor and sensor chip immobilized with polyclonal antibodies specific to each of the target pathogens. O157:H7, S. enteritidis, and L. monocytogenes in chicken were detected simultaneously at an inoculum dose of 14, 6, and 28 CFU/25 g, respectively. Our method using a custom-built multichannel SPR biosensor and enrichment in SEB is expected as a rapid and simultaneous detection method for low levels of O157:H7, S. enteritidis, and L. monocytogenes in food. Our method is expected as a rapid and simultaneous detection method for pathogens at very low levels. It has great potential for safety control of food and microbiological detection applications. © 2017 Institute of Food Technologists®.

  7. COGNITIVE RESERVE IN AGING

    Science.gov (United States)

    Tucker, Adrienne M.; Stern, Yaakov

    2011-01-01

    Cognitive reserve explains why those with higher IQ, education, occupational attainment, or participation in leisure activities evidence less severe clinical or cognitive changes in the presence of age-related or Alzheimer’s disease pathology. Specifically, the cognitive reserve hypothesis is that individual differences in how tasks are processed provide reserve against brain pathology. Cognitive reserve may allow for more flexible strategy usage, an ability thought to be captured by executive functions tasks. Additionally, cognitive reserve allows individuals greater neural efficiency, greater neural capacity, and the ability for compensation via the recruitment of additional brain regions. Taking cognitive reserve into account may allow for earlier detection and better characterization of age-related cognitive changes and Alzheimer’s disease. Importantly, cognitive reserve is not fixed but continues to evolve across the lifespan. Thus, even late-stage interventions hold promise to boost cognitive reserve and thus reduce the prevalence of Alzheimer’s disease and other age-related problems. PMID:21222591

  8. HYDROCARBONS RESERVES IN VENEZUELA

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez Cruz, D.J.

    2007-07-01

    Venezuela is an important player in the energy world, because of its hydrocarbons reserves. The process for calculating oil and associated gas reserves is described bearing in mind that 90% of the gas reserves of Venezuela are associated to oil. Likewise, an analysis is made of the oil reserves figures from 1975 to 2003. Reference is also made to inconsistencies found by international experts and the explanations offered in this respect by the Ministry of Energy and Petroleum (MENPET) and Petroleos de Venezuela (PDVSA) regarding the changes that took place in the 1980s. In turn, Hubbert's Law is explained to determine peak production of conventional oil that a reservoir or field will reach, as well as its relationship with remaining reserves. Emphasis is placed on the interest of the United Nations on this topic. The reserves of associated gas are presented along with their relationship with the different crude oils that are produced and with injected gas, as well as with respect to the possible changes that would take place in the latter if oil reserves are revised. Some recommendations are submitted so that the MENPET starts preparing the pertinent policies ruling reserves. (auth)

  9. Ovarian reserve parameters

    DEFF Research Database (Denmark)

    Bentzen, J G; Forman, Julie Lyng; Pinborg, Anja

    2012-01-01

    2-5 of the menstrual cycle or during withdrawal bleeding, blood sampling and transvaginal sonography was performed. After adjusting for age, ovarian reserve parameters were lower among users than among non-users of hormonal contraception: serum AMH concentration by 29.8% (95% CI 19.9 to 38...... was observed between duration of hormonal-contraception use and ovarian reserve parameters. No dose-response relation was found between the dose of ethinyloestradiol and AMH or AFC. This study indicates that ovarian reserve markers are lower in women using sex steroids for contraception. Thus, AMH...... concentration and AFC may not retain their accuracy as predictors of ovarian reserve in women using hormonal contraception. Serum anti-Müllerian hormone (AMH) concentration is an indirect marker of the number of small follicles in the ovary and thereby the ovarian reserve. The AMH concentration is now widely...

  10. SPR imaging biosensor for the quantitation of fibronectin concentration in blood samples.

    Science.gov (United States)

    Sankiewicz, Anna; Romanowicz, Lech; Pyc, Marlena; Hermanowicz, Adam; Gorodkiewicz, Ewa

    2018-02-20

    The purpose of this study was presentation of a new biosensor capable of determination of fibronectin. This biosensor was based on the specific interaction of anti-fibronectin antibody produced in rabbit with fibronectin. The surface plasmon resonance imaging (SPRI) technique was used as a detecting method. Optimization and characterization properties of the biosensor were studied. The determination of fibronectin concentration in natural samples was done. The results were compared with a reference method (Enzyme-Linked Immunosorbent Assay-ELISA). The analytically useful dynamic response range of biosensor is between 5 and 400ngmL -1 . The detection limit is 1.5ngmL -1 and limit quantification is 5ngmL -1 . The proposed SPRI biosensor showed good selectivity for potential interferences. It was applied to determine fibronectin concentrations in plasma of healthy donors and of patients after thermal injury. Good correlations between results obtained using the SPRI biosensor and ELISA test (correlation coefficients for healthy donors 0.996, for patients 0.984) were obtained. The average fibronectin concentration of healthy donors was 140.5±24.6μgmL -1 and the average fibronectin concentration of patients was 601.5±72.1μgmL -1 , which was in agreement with results obtained by other investigators. The obtained results indicate that the developed biosensor may be a candidate for monitoring fibronectin concentration in blood samples. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. SPR imaging based electronic tongue via landscape images for complex mixture analysis.

    Science.gov (United States)

    Genua, Maria; Garçon, Laurie-Amandine; Mounier, Violette; Wehry, Hillary; Buhot, Arnaud; Billon, Martial; Calemczuk, Roberto; Bonnaffé, David; Hou, Yanxia; Livache, Thierry

    2014-12-01

    Electronic noses/tongues (eN/eT) have emerged as promising alternatives for analysis of complex mixtures in the domain of food and beverage quality control. We have recently developed an electronic tongue by combining surface plasmon resonance imaging (SPRi) with an array of non-specific and cross-reactive receptors prepared by simply mixing two small molecules in varying and controlled proportions and allowing the mixtures to self-assemble on the SPRi prism surface. The obtained eT generated novel and unique 2D continuous evolution profiles (CEPs) and 3D continuous evolution landscapes (CELs) based on which the differentiation of complex mixtures such as red wine, beer and milk were successful. The preliminary experiments performed for monitoring the deterioration of UHT milk demonstrated its potential for quality control applications. Furthermore, the eT exhibited good repeatability and stability, capable of operating after a minimum storage period of 5 months. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Skyline Reservation System

    Data.gov (United States)

    US Agency for International Development — Flight reservation application used for in-country flights by USAID and DoS staff in Afghanistan. The application is managed and maintained by the vendor and USAID...

  13. Geomechanical testing of MRIG-9 core for the potential SPR siting at the Richton salt dome.

    Energy Technology Data Exchange (ETDEWEB)

    Dunn, Dennis P.; Broome, Scott Thomas; Bronowski, David R.; Bauer, Stephen J.; Hofer, John H.

    2009-02-01

    A laboratory testing program was developed to examine the mechanical behavior of salt from the Richton salt dome. The resulting information is intended for use in design and evaluation of a proposed Strategic Petroleum Reserve storage facility in that dome. Core obtained from the drill hole MRIG-9 was obtained from the Texas Bureau of Economic Geology. Mechanical properties testing included: (1) acoustic velocity wave measurements; (2) indirect tensile strength tests; (3) unconfined compressive strength tests; (4) ambient temperature quasi-static triaxial compression tests to evaluate dilational stress states at confining pressures of 725, 1450, 2175, and 2900 psi; and (5) confined triaxial creep experiments to evaluate the time-dependent behavior of the salt at axial stress differences of 4000 psi, 3500 psi, 3000 psi, 2175 psi and 2000 psi at 55 C and 4000 psi at 35 C, all at a constant confining pressure of 4000 psi. All comments, inferences, discussions of the Richton characterization and analysis are caveated by the small number of tests. Additional core and testing from a deeper well located at the proposed site is planned. The Richton rock salt is generally inhomogeneous as expressed by the density and velocity measurements with depth. In fact, we treated the salt as two populations, one clean and relatively pure (> 98% halite), the other salt with abundant (at times) anhydrite. The density has been related to the insoluble content. The limited mechanical testing completed has allowed us to conclude that the dilatational criteria are distinct for the halite-rich and other salts, and that the dilation criteria are pressure dependent. The indirect tensile strengths and unconfined compressive strengths determined are consistently lower than other coastal domal salts. The steady-state-only creep model being developed suggests that Richton salt is intermediate in creep resistance when compared to other domal and bedded salts. The results of the study provide only

  14. 24 CFR 572.125 - Replacement reserves.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Replacement reserves. 572.125...) Homeownership Program Requirements-Implementation Grants § 572.125 Replacement reserves. (a) Purpose. A single replacement reserve may be established for the homeownership program only if HUD determines it is necessary to...

  15. 24 CFR 891.745 - Replacement reserve.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Replacement reserve. 891.745... and Individuals-Section 162 Assistance § 891.745 Replacement reserve. The general requirements for the replacement reserve are provided in § 891.605. For projects funded under §§ 891.655 through 891.790, the...

  16. Spinning Reserve From Responsive Loads

    Energy Technology Data Exchange (ETDEWEB)

    Kirby, B.J.

    2003-04-08

    Responsive load is the most underutilized reliability resource available to the power system today. It is currently not used at all to provide spinning reserve. Historically there were good reasons for this, but recent technological advances in communications and controls have provided new capabilities and eliminated many of the old obstacles. North American Electric Reliability Council (NERC), Federal Energy Regulatory Commission (FERC), Northeast Power Coordinating Council (NPCC), New York State Reliability Council (NYSRC), and New York Independent System Operator (NYISO) rules are beginning to recognize these changes and are starting to encourage responsive load provision of reliability services. The Carrier ComfortChoice responsive thermostats provide an example of these technological advances. This is a technology aimed at reducing summer peak demand through central control of residential and small commercial air-conditioning loads. It is being utilized by Long Island Power Authority (LIPA), Consolidated Edison (ConEd), Southern California Edison (SCE), and San Diego Gas and Electric (SDG&E). The technology is capable of delivering even greater response in the faster spinning reserve time frame (while still providing peak reduction). Analysis of demand reduction testing results from LIPA during the summer of 2002 provides evidence to back up this claim. It also demonstrates that loads are different from generators and that the conventional wisdom, which advocates for starting with large loads as better ancillary service providers, is flawed. The tempting approach of incrementally adapting ancillary service requirements, which were established when generators were the only available resources, will not work. While it is easier for most generators to provide replacement power and non-spinning reserve (the slower response services) than it is to supply spinning reserve (the fastest service), the opposite is true for many loads. Also, there is more financial

  17. Demand as frequency controlled reserve

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Z.; Togeby, M.; OEstergaard, J.

    2008-09-15

    Using demand as frequency controlled reserve (DFR) is an emerging technology which allow demand to participate actively in maintaining the system operation without reducing the energy service delivered to the customer and without need of user interaction. The basic premise is that traditional frequency controlled reserves from power plants and interconnections with neighbouring systems can be costly, slow and not fulfil the need for future power grids with a high share of wind power and fewer central power plants, and an intention to perform flexible operation such as is landing. Electricity demands, on the other hand, have advantages as frequency reserve including fast activation speed, smooth linear activation, low expected costs, and well-dispersed in the distribution grid. The main challenge of DFR is new methods for monitoring the available capacity. This project has investigated the technology of using electricity demands for providing frequency reserve to power systems. Within the project the potential and economy of DFR compatible loads in Denmark has been investigated, control logic has been designed, power system impact has been investigated, potential business models has been evaluated and an implementation strategy has been suggested. The tasks and goals of the project have been successfully accomplished based on which the conclusion and future recommendation are made. This project has developed the DFR technology that enables electricity demands to autonomously disconnect or reconnect to the grid in response to system frequency variations. The developed DFR technology is proved to be a promising technology from several perspectives. Technically, using DFR is feasible to provide reserves and enhance power system frequency control, while fulfilling technical requirements such as linear activation (or reconnection) according to frequency (or time). Environmentally, the DFR technology is pollution free in contrast to traditional reserves from generation

  18. Handbook on loss reserving

    CERN Document Server

    Schmidt, Klaus; Schnaus, Anja

    2016-01-01

    This handbook presents the basic aspects of actuarial loss reserving. Besides the traditional methods, it also includes a description of more recent ones and a discussion of certain problems occurring in actuarial practice, like inflation, scarce data, large claims, slow loss development, the use of market statistics, the need for simulation techniques and the task of calculating best estimates and ranges of future losses. In property and casualty insurance the provisions for payment obligations from losses that have occurred but have not yet been settled usually constitute the largest item on the liabilities side of an insurer's balance sheet. For this reason, the determination and evaluation of these loss reserves is of considerable economic importance for every property and casualty insurer. Actuarial students, academics as well as practicing actuaries will benefit from this overview of the most important actuarial methods of loss reserving by developing an understanding of the underlying stochastic models...

  19. SUIKERBOSRAND NATURE RESERVE

    African Journals Online (AJOL)

    Suikerbosrand Nature Reserve and fts educational facilities are run by the Transvaal. Division of. Nature Conservation. ... tion and the education facilities provided. The former are utilized mainly by the general public ... artist Paul Bosman (already reviewed in the EEASA newsletter). The co-founders of the Foundation are.

  20. Session 7: Reserve

    International Nuclear Information System (INIS)

    Bailey, R.; Crockford, G.

    2001-01-01

    The reserve session was devoted to some issues that came up through the workshop, which were grouped into three main areas: The Global Accelerator Network, Problems of stress and how to get organized to minimize them, What should an operations group be responsible for? This paper summarizes the discussions that took place. (author)

  1. School Shootings Stun Reservation

    Science.gov (United States)

    Borja, Rhea R.; Cavanagh, Sean

    2005-01-01

    This article deals with the impact brought by the school shootings at Red Lake Indian Reservation in Minnesota to the school community. A deeply troubled 16-year-old student shot and killed seven other people and himself at a high school. The nation's deadliest school attack since the 1999 slayings at Colorado's suburban Columbine High School took…

  2. SUIKERBOSRAND NATURE RESERVE

    African Journals Online (AJOL)

    reserve, the total length being 66 km with six overnight huts. There are also the BokmakiePie. Nature Troil. and the Cheetah Interpretive Troil. which can be used by day visitors. The former has two loops, one of 10 km and another of 17 km. The. Cheetah Troil. is much shorter and various points of interest are interpreted en ...

  3. Results of the Weeks Island Strategic Petroleum Reserve Oil Leak Risk Assessment Study

    International Nuclear Information System (INIS)

    Molecke, M.A.; Hinkebein, T.E.; Bauer, S.J.; Linn, J.K.

    1998-12-01

    This study evaluated multiple, long-term environmental oil-contamination risk scenarios that could result from the potential leakage of UP to 1.5 million barrels of crude oil entombed in the Weeks Island SPR mine following site decommissioning and abandonment, and up to 100 years thereafter. This risk assessment also provides continuity with similar risk evaluations performed earlier and documented in the 1995 DOE Environmental Assessment for Decommissioning the Strategic Petroleum Reserve Weeks Island Facility (EA). This current study was requested by the DOE to help them determine if their previous Finding of No Significant Impact (FONSI), in the EA, is still valid or needs to be rescinded. Based on the calculated environmental risk results (in terms of clean-up and remediation expenses) presented in this risk assessment, including the calculated average likelihoods of oil release and potential oil-leakage volumes, none of the evaluated risk events would appear to satisfy the definition of significant environmental impact in National Environmental Policy Act (NEPA) terminology. The DOE may combine these current results with their earlier evaluations and interpretations in the 1995 EA in order to assess whether the existing FONSI is still accurate, acceptable, and valid. However, from a risk evaluation standpoint, the assessment of impacts appears to be the same whether only 10,000 to 30,000 barrels of crude oil (as considered in the 1995 EA), or up to 1.5 million barrels of oil (as considered herein) are abandoned in the Weeks Island SPR facility

  4. Improving the performance of brine wells at Gulf Coast strategic petroleum reserve sites

    Energy Technology Data Exchange (ETDEWEB)

    Owen, L.B.; Quong, R. (eds.)

    1979-11-05

    At the request of the Department of Energy, field techniques were developed to evaluate and improve the injection of brine into wells at Strategic Petroleum Reserve (SPR) sites. These wells are necessary for the disposal of saturated brine removed from salt domes where oil is being stored. The wells, which were accepting brine at 50 percent or less of their initial design rates, were impaired by saturated brine containing particulates that deposited on the sand face and in the geologic formation next to the wellbore. Corrosion of the brine-disposal pipelines and injection wells contributed to the impairment by adding significant amounts of particulates in the form of corrosion products. When tests were implemented at the SPR sites, it was found that the poor quality of injected brines was the primary cause of impaired injection; that granular-media filtration, when used with chemical pretreatment, is an effective method for removing particulates from hypersaline brine; that satisfactory injection-well performance can be attained with prefiltered brines; and that corrosion rates can be substantially reduced by oxygen-scavenging.

  5. Bryan Mound InSAR Analysis U.S. Strategic petroleum Reserve.

    Energy Technology Data Exchange (ETDEWEB)

    Lord, Anna C. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-06-01

    The U.S. Strategic Petroleum Reserve (SPR) is a stockpile of emergency crude oil to be tapped into if a disruption in the nation's oil supply occurs. The SPR is comprised of four salt dome sites. Subsidence surveys have been conducted either annually or biennially at all four sites over the life of the program. Monitoring of surface behavior is a first line defense to detecting possible subsurface cavern integrity issues. Over the life of the Bryan Mound site, subsidence rates over abandoned Cavern 3 have continuously been the highest at the site. In an effort to try and understand the subsurface dynamics, specifically over Bryan Mound Cavern 3, historic interferometric synthetic aperture radar (InSAR) data was acquired and processed by TRE Altamira. InSAR involves the processing of multiple satellite synthetic aperture radar scenes acquired across the same location of the Earth's surface at different times to map surface deformation. The analysis of the data has the ability to detect millimeters of motion spanning days, months, year and decades, across specific sites. The intent in regards to the Bryan Mound site was (1) to confirm the higher subsidence rates recorded over abandoned Cavern 3 indicated by land survey and (2) understand the regional surface behavior. This report describes the InSAR analysis results, how those results compare to the historical collection of land survey data, and what additional information the data has provided towards understanding the response recorded at the surface.

  6. The Strategic Petroleum Reserve

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    The Strategic Petroleum Reserve program was set into motion by the 1975 Energy Policy and Conservation Act (EPCA). By 1990, 590 million barrels of oil had been placed in storage. Salt domes along the Gulf Coast offered ideal storage. Both sweet'' and sour'' crude oil have been acquired using various purchase options. Drawdown, sale, and distribution of the oil would proceed according to guidelines set by EPCA in the event of a severe energy supply disruption. (SM)

  7. Real-time monitoring of mycobacterium genomic DNA with target-primed rolling circle amplification by a Au nanoparticle-embedded SPR biosensor.

    Science.gov (United States)

    Xiang, Yang; Zhu, Xiaoyan; Huang, Qing; Zheng, Junsong; Fu, Weiling

    2015-04-15

    In this study, we developed a surface plasmon resonance (SPR) DNA biosensor array based on target-primed rolling circle amplification (RCA) for isothermal and rapid detection of two pathogenic mycobacteria, Mycobacterium tuberculosis complex (MTBC) and Mycobacterium avium complex (MAC).The species-specific padlock probe (PLP) was designed to target the sequence in 16S-23S rRNA gene internal transcribed spacer (ITS). After ligation, the circularized PLP could be primed by the target sequence to initial RCA. The RCA performed simultaneously with the cleavage reaction to produce small fragments of single strand DNA which immediately hybridized with the probe immobilized on the sensor chip without denaturation. This process caused SPR angle changes on the chip surface, which made the detection for analysis from the solution achievable, and dynamic real-time RCA monitoring of mycobacterium possible. Besides, Au nanoparticles (AuNPs) were directly assembled onto the surface of the sensor chip via hexanedithiol (HDT) for the enhancement of sensitivity as a label-free detection system. Experimental results show that the signal enhancement by the target-primed RCA together with AuNPs-embedded surface caused at least10-fold increased sensitivity as compared with conventional RCA on bare SPR chip method. Within 40min amplification duration as low as 20amol of synthetic targets and 10(4)CFUmL(-1) of genomic DNA from clinical samples can be detected. The proposed method not only provides a simple design idea for liquid-phase amplification monitoring, but also apply it in clinical pathogen detection, which holds great promise in ultrasensitive bioassay in the future. Copyright © 2014. Published by Elsevier B.V.

  8. [Hypertrophy and coronary reserve].

    Science.gov (United States)

    Motz, W; Scheler, S

    2008-12-01

    Left ventricular hypertrophy represents the structural mechanism of adaptation of the left ventricle as the answer of a chronic pressure overload in arterial hypertension. Initially an increment in left ventricular wall thickness occurs. In this stadium of "concentric hypertrophy" LV systolic wall stress, LV ejection fraction and myocardial oxygen consumption per weight unit myocardium remain unchanged. In the further time course of disease LV dilatation will be present. In this phase of "excentric hypertrophy" LV systolic wall stress and myocardial oxygen consumption per weight unit myocardium rise and LV ejection fraction decreases. Patients with arterial hypertension frequently complain of angina pectoris. Angina pectoris and the positive exercise tolerance test or the positive myocardial scintigraphy are the consequence of the impaired coronary flow reserve. The coronary flow reserve is diminished due to structural and functional changes of the coronary circulation. ACE-inhibitors and AT1-receptor blockers cause a significant improvement of coronary flow reserve and regression of both left ventricular hypertrophy and myocardial fibrosis.

  9. SPR/MS

    DEFF Research Database (Denmark)

    Borch, Jonas; Roepstorff, Peter

    2010-01-01

    Surface plasmon resonance is widely used to study binding interactions with proteins, potentially yielding information on kinetics, thermodynamics and active concentrations. However, the technology cannot identify the involved interaction partners. Mass spectrometry, on the other hand, can be use...

  10. Fractional Reserve Banking

    OpenAIRE

    Andreasen, Niels; Bjerregaard, Mads; Lund, Jonas; Olsen, Ove Bitsch; Rasmussen, Andreas Dalgas

    2012-01-01

    Projektet er bygget op omkring kritisk realisme, som er det gennemgående videnskabelige fundament til undersøgelsen af hvilke strukturelle grunde der er til finansiel ustabilitet i Danmark. Projektet går i dybden med Fractional Reserve Banking og incitamentsstrukturen i banksystemet. Vi bevæger os både på det makro- og mikroøkonomiske niveau i analysen. På makro niveau bruger vi den østrigske skole om konjunktur teori (The Positive Theory of the Cycle). På mikro niveau arbejder vi med princip...

  11. Protein-Flavonoid Interaction Studies by a Taylor Dispersion Surface Plasmon Resonance (SPR Technique: A Novel Method to Assess Biomolecular Interactions

    Directory of Open Access Journals (Sweden)

    Preejith P. Vachali

    2016-02-01

    Full Text Available Flavonoids are common polyphenolic compounds widely distributed in fruits and vegetables. These pigments have important pharmacological relevance because emerging research suggests possible anti-cancer and anti-inflammatory properties as well other beneficial health effects. These compounds are relatively hydrophobic molecules, suggesting the role of blood transport proteins in their delivery to tissues. In this study, we assess the binding interactions of four flavonoids (kaempferol, luteolin, quercetin, and resveratrol with human serum albumin (HSA, the most abundant protein in the blood, and with glutathione S-transferase pi isoform-1 (GSTP1, an enzyme with well-characterized hydrophobic binding sites that plays an important role in detoxification of xenobiotics with reduced glutathione, using a novel Taylor dispersion surface plasmon resonance (SPR technique. For the first time, HSA sites revealed a high-affinity binding site for flavonoid interactions. Out of the four flavonoids that we examined, quercetin and kaempferol showed the strongest equilibrium binding affinities (KD of 63 ± 0.03 nM and 37 ± 0.07 nM, respectively. GSTP1 displayed lower affinities in the micromolar range towards all of the flavonoids tested. The interactions of flavonoids with HSA and GSTP1 were studied successfully using this novel SPR assay method. The new method is compatible with both kinetic and equilibrium analyses.

  12. A Policy Analysis of Reserve Retirement Reform

    Science.gov (United States)

    2013-01-01

    adapted their manning requirements to this retention. Perhaps tasks and jobs have been designed to accommodate the reten - tion profile produced by the...a reward for a long career of service, a benefit to help transition to the civilian economy, and a means of securing the reten - tion of career...to determine their likely effect on active reten - tion, reserve affiliation after leaving an active component, reserve retention, and reserve

  13. Body reserves in intra-African migrants

    NARCIS (Netherlands)

    Nwaogu, Chima; Cresswell, Will

    Avian migration has been shown to be a life history strategy for surviving environmental resource variability, but it requires increased body reserves for long distance flight. Fat reserves make excellent energy stores for barrier crossing, whereas proteins generate less energy for the same mass of

  14. 30 CFR 253.44 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false [Reserved] 253.44 Section 253.44 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL SPILL FINANCIAL RESPONSIBILITY FOR OFFSHORE FACILITIES Requirements for Submitting OSFR Information § 253.44 [Reserved] ...

  15. 7 CFR 1709.2 Policy. - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false [Reserved] 1709.2 Policy. Section 1709.2 Policy. Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE ASSISTANCE TO HIGH ENERGY COST COMMUNITIES General Requirements § 1709.2 Policy. [Reserved] ...

  16. 7 CFR 3560.65 - Reserve account.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Reserve account. 3560.65 Section 3560.65 Agriculture... DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Direct Loan and Grant Origination § 3560.65 Reserve account... account that meets requirements of § 3560.306. At a minimum, the borrower must agree to make monthly...

  17. 7 CFR 1780.8 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false [Reserved] 1780.8 Section 1780.8 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS General Policies and Requirements § 1780.8 [Reserved] ...

  18. 7 CFR 1780.5 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false [Reserved] 1780.5 Section 1780.5 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS General Policies and Requirements § 1780.5 [Reserved] ...

  19. 7 CFR 1780.12 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false [Reserved] 1780.12 Section 1780.12 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS General Policies and Requirements § 1780.12 [Reserved] ...

  20. Are uranium reserves adequate?

    International Nuclear Information System (INIS)

    Anon.

    2006-01-01

    Against a backdrop of growing concerns about global warming and geopolitical pressures on fossil energies, especially natural gas and oil, interest in nuclear power has revived considerably. Conscious of its addiction to oil and reeling from a series of gigantic blackouts, the United States, in the words of its president, must 'aggressively move forward with the construction of nuclear power plants'. Some European countries have approved new power plant construction (Finland and France), while the more reserved ones (Belgium, Germany and Sweden) have begun to show a change in attitude. Asia, meanwhile, is host to the planet's largest number of potential nuclear construction projects in this first half of the 21. century. All these signs point to a sharp rise in uranium consumption, the basic fuel for these plants. But are there enough resources to support a nuclear revival on a planetary scale? The publication of the Red Book on uranium in late May 2006 was an opportunity for Thierry Dujardin, Deputy Director of Science and Development at the OECD's Nuclear Energy Agency, to take stock of resources. He gives his opinion in this paper

  1. Reserve valuation in electric power systems

    Science.gov (United States)

    Ruiz, Pablo Ariel

    Operational reliability is provided in part by scheduling capacity in excess of the load forecast. This reserve capacity balances the uncertain power demand with the supply in real time and provides for equipment outages. Traditionally, reserve scheduling has been ensured by enforcing reserve requirements in the operations planning. An alternate approach is to employ a stochastic formulation, which allows the explicit modeling of the sources of uncertainty. This thesis compares stochastic and reserve methods and evaluates the benefits of a combined approach for the efficient management of uncertainty in the unit commitment problem. Numerical studies show that the unit commitment solutions obtained for the combined approach are robust and superior with respect to the traditional approach. These robust solutions are especially valuable in areas with a high proportion of wind power, as their built-in flexibility allows the dispatch of practically all the available wind power while minimizing the costs of operation. The scheduled reserve has an economic value since it reduces the outage costs. In several electricity markets, reserve demand functions have been implemented to take into account the value of reserve in the market clearing process. These often take the form of a step-down function at the reserve requirement level, and as such they may not appropriately represent the reserve value. The value of reserve is impacted by the reliability, dynamic and stochastic characteristics of system components, the system operation policies, and the economic aspects such as the risk preferences of the demand. In this thesis, these aspects are taken into account to approximate the reserve value and construct reserve demand functions. Illustrative examples show that the demand functions constructed have similarities with those implemented in some markets.

  2. Strategic Petroleum Reserve annual/quarterly report

    Energy Technology Data Exchange (ETDEWEB)

    1993-02-16

    During 1992 the Department continued planning activities for the expansion of the Strategic Petroleum Reserve to one billion barrels. A draft Environmental Impact Statement for the five candidate sites was completed in October 1992, and a series of public hearings was held during December 1992. Conceptual design engineering activities, life cycle cost estimates and geotechnical studies to support the technical requirements for an Strategic Petroleum Reserve Plan Amendment were essentially completed in December 1992. At the end of 1992, the Strategic Petroleum Reserve crude oil inventory was 574.7 million barrels and an additional 1.7 million barrels was in transit to the Reserve. During 1992 approximately 6.2 million barrels of crude oil were acquired for the Reserve. A Department of Energy Tiger Team Environmental, Safety and Health (ES&H) Assessment was conducted at the Strategic Petroleum Reserve from March 9 through April 10, 1992. In general, the Tiger Team found that Strategic Petroleum Reserve activities do not pose undue environmental, safety or health risks. The Strategic Petroleum Reserve`s Final Corrective Action Plan, prepared in response to the Tiger Team assessment, was submitted for Department approval in December 1992. On November 18, 1992, the Assistant Secretary for Fossil Energy selected DynMcDennott Petroleum Operations Company to provide management and operating services for the Strategic Petroleum Reserve for a period of 5 years commencing April 1, 1993. DynMcDermott will succeed Boeing Petroleum Services, Inc.

  3. Naval Petroleum and Oil Shale Reserves

    International Nuclear Information System (INIS)

    1992-01-01

    During fiscal year 1992, the reserves generated $473 million in revenues, a $181 million decrease from the fiscal year 1991 revenues, primarily due to significant decreases in oil and natural gas prices. Total costs were $200 million, resulting in net cash flow of $273 million, compared with $454 million in fiscal year 1991. From 1976 through fiscal year 1992, the Naval Petroleum and Oil Shale Reserves generated more than $15 billion in revenues and a net operating income after costs of $12.5 billion. In fiscal year 1992, production at the Naval Petroleum Reserves at maximum efficient rates yielded 26 million barrels of crude oil, 119 billion cubic feet of natural gas, and 164 million gallons of natural gas liquids. From April to November 1992, senior managers from the Naval Petroleum and Oil Shale Reserves held a series of three workshops in Boulder, Colorado, in order to build a comprehensive Strategic Plan as required by Secretary of Energy Notice 25A-91. Other highlights are presented for the following: Naval Petroleum Reserve No. 1--production achievements, crude oil shipments to the strategic petroleum reserve, horizontal drilling, shallow oil zone gas injection project, environment and safety, and vanpool program; Naval Petroleum Reserve No. 2--new management and operating contractor and exploration drilling; Naval Petroleum Reserve No. 3--steamflood; Naval Oil Shale Reserves--protection program; and Tiger Team environmental assessment of the Naval Petroleum and Oil Shale Reserves in Colorado, Utah, and Wyoming

  4. Environmental Assessment on the leasing of the Strategic Petroleum Reserve, St. James Terminal, St. James Parish, Louisiana

    International Nuclear Information System (INIS)

    1995-01-01

    The US Department of Energy (DOE) proposes to lease the Strategic Petroleum Reserve's (SPR) St. James Terminal to private industry. The St. James Terminal consists of six storage tanks, a pumping station, two maine docks and ancillary facilities. DOE believes that the St. James Terminal presents an opportunity to establish a government- industry arrangement that could more effectively use this asset to serve the nations's oil distribution needs, reduce the operational cost of the SPR, and provide a source of revenue for the Government. DOE solicited interest in leasing its distribution facilities in a notice published March 16, 1994. In response, industry has expressed interest in leasing the St. James Terminal, as well as several DOE pipelines, to enhance the operation of its own facilities or to avoid having to construct new ones. Under such a lease, industry use would be subordinate to DOE use in the event of a national energy emergency. This Environmental Assessment describes the proposed leasing operation, its alternatives, and potential environmental impacts. Based on this analyses, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) OF 1969 and has issued the Finding of No Significant Impact (FONSI)

  5. West Hackberry Strategic Petroleum Reserve site brine-disposal monitoring, year 1 report. Volume 1. Executive summary. Final report

    Energy Technology Data Exchange (ETDEWEB)

    DeRouen, L.R.; Hann, R.W.; Casserly, D.M.; Giammona, C.; Lascara, V.J. (eds.)

    1983-02-01

    The physical, chemical and biological attributes are described for: (1) a coastal marine environment centered about a Department of Energy Strategic Petroleum Reserve (SPR) brine disposal site located 11.4 km off the southwest coast of Louisiana; and (2) the lower Calcasieu and Sabine estuarine systems that provide leach waters for the SPR project. During the study period, the daily discharge averaged 529,000 barrels of 216 0/00 brine, representing a loading of 18,000 metric tons of salt per day. The objective of this study are: (1) characterize the environment in terms of physical, chemical and biological attributes; (2) determine if significant adverse changes in ecosystem productivity and stability of the biological community are occurring as a result of brine discharge; and (3) determine the magnitude of any change observed. This report describes the methodology and significant results of the first year's monitoring effort of the West Hackberry brine disposal site. The investigative tasks, presented as separate sections, are: Physical Oceanography, Estuarine Hydrology and Hydrography, Analysis of Discharge Plume, Water and Sediment Quality, Special Pollutant Surveys, Benthos, Nekton, Phytoplankton, Zooplankton and Data Management.

  6. Strategic Petroleum Reserve: Annual/quarterly report

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-16

    Section 165 of the Energy Policy and Conservation Act (Public Law 94-163), as amended, requires the Secretary of Energy to submit annual and quarterly reports to the President and the Congress on activities of the Strategic Petroleum Reserve. This report combines the fourth quarter 1993 Quarterly Report with the 1993 Annual Report. Key activities described include appropriations; life extension planning; expansion planning; Strategic Petroleum Reserve oil acquisition; the oil stabilization program; and the refined petroleum product reserve test programs. Sections of this report also describe the program mission; the storage facility development program; environmental compliance; budget and finance; and drawdown and distribution.

  7. Fractional Reserve in Banking System

    OpenAIRE

    Valkonen, Maria

    2016-01-01

    This thesis is aimed to provide understanding of the role of the fractional reserve in the mod-ern banking system worldwide and particularly in Finland. The fractional reserve banking is used worldwide, but the benefits of this system are very disputable. On the one hand, experts say that the fractional reserve is a necessary instrument for the normal business and profit making. On the other hand, sceptics openly criticize the fractional reserve system and blame it for fiat money (money n...

  8. Analysis of Multi-Arm Caliper Data for the U.S. Strategic Petroleum Reserve

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, Barry L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-03-01

    The U.S. Strategic Petroleum Reserve (SPR) has an increasing reliance on mul t i - arm caliper surveys to assess the integrity of casing for cavern access wells and to determine priorities for casing remediation. Multi - arm caliper (MAC) surveys provide a view of well casing deformation by reporting radial measurements of the inner cas ing wall as the tool is drawn through the casing. Over the last several years the SPR has collected a large number of modern MAC surveys. In total, these surveys account for over 100 million individual measurements. The surveys were collected using diff ering survey vendors and survey hardware. This has resulted in a collection of disparate data sets which confound attempts to make well - to - well or time - dependent evaluations. In addition, the vendor supplied MAC interpretations often involve variables wh ich are not well defined or which may not be applicable to casings for cavern access wells. These factors reduce the usability of these detailed data sets. In order to address this issue and provide an independent analysis of multi - arm caliper survey data, Sandia National Labs has developed processing techniques and analysis variables which allow for the comparison of MAC survey data regardless of the source of the survey data. These techniques use the raw radial arm information and newly developed analysis variables to assess the casing status and provide a means for well - to - well and time - dependent analyses. Well - to - well and t ime - dependent investigation of the MAC survey data provide s information to prioritize well remediation activities and identify wells with integrity issues. This paper presents the challenges in using disparate MAC survey data, techniques developed to address these challenges and some o f the insights gained from these new techniques.

  9. Strategic petroleum reserve caverns casing damage update 1997

    Energy Technology Data Exchange (ETDEWEB)

    Munson, D.E.; Molecke, M.A.; Neal, J.T. [and others

    1998-01-01

    Hanging casing strings are used for oil and brine transfer in the domal salt storage caverns of the Strategic Petroleum Reserve (SPR). Damage to these casings is of concern because hanging string replacement is costly and because of implications on cavern stability. Although the causes of casing damage are not always well defined, many events leading to damage are assumed to be the result of salt falls impacting the hanging strings. However, in some cases, operational aspects may be suspected. The history of damage to hanging strings is updated in this study to include the most recent events. Potential general domal and local operational and material factors that could influence the tendency for caverns to have salt falls are examined in detail. As a result of this examination, general factors, such as salt dome anomalies and crude type, and most of the operational factors, such as geometry, location and depressurizations, are not believed to be primary causes of casing damage. Further analysis is presented of the accumulation of insolubles during cavern solutioning and accumulation of salt fall material on the cavern floor. Inaccuracies in sump geometry probably make relative cavern insolubles contents uncertain. However, determination of the salt fall accumulations, which are more accurate, suggest that the caverns with the largest salt fall accumulations show the greatest number of hanging string events. There is good correlation between the accumulation rate and the number of events when the event numbers are corrected to an equivalent number for a single hanging string in a quiescent, operating cavern. The principal factor that determines the propensity for a cavern to exhibit this behavior is thought to be the effect of impurity content on the fracture behavior of salt.

  10. 27 CFR 27.205 - [Reserved

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false [Reserved] 27.205 Section 27.205 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS IMPORTATION OF DISTILLED SPIRITS, WINES, AND BEER Requirements for Liquor Bottles...

  11. 7 CFR 3560.306 - Reserve account.

    Science.gov (United States)

    2010-01-01

    ...) As projects age, the required reserve account level may be adjusted to meet anticipated “life-cycle...) Purpose. To meet the major capital expense needs of a housing project, borrowers must establish and... be deemed to contain surplus funds when the balance at the end of the housing project's fiscal year...

  12. Biosphere reserves: Attributes for success.

    Science.gov (United States)

    Van Cuong, Chu; Dart, Peter; Hockings, Marc

    2017-03-01

    Biosphere reserves established under the UNESCO Man and the Biosphere Program aim to harmonise biodiversity conservation and sustainable development. Concerns over the extent to which the reserve network was living up to this ideal led to the development of a new strategy in 1995 (the Seville Strategy) to enhance the operation of the network of reserves. An evaluation of effectiveness of management of the biosphere reserve network was called for as part of this strategy. Expert opinion was assembled through a Delphi Process to identify successful and less successful reserves and investigate common factors influencing success or failure. Ninety biosphere reserves including sixty successful and thirty less successful reserves in 42 countries across all five Man and the Biosphere Program regions were identified. Most successful sites are the post-Seville generation while the majority of unsuccessful sites are pre-Seville that are managed as national parks and have not been amended to conform to the characteristics that are meant to define a biosphere reserve. Stakeholder participation and collaboration, governance, finance and resources, management, and awareness and communication are the most influential factors in the success or failure of the biosphere reserves. For success, the biosphere reserve concept needs to be clearly understood and applied through landscape zoning. Designated reserves then need a management system with inclusive good governance, strong participation and collaboration, adequate finance and human resource allocation and stable and responsible management and implementation. All rather obvious but it is difficult to achieve without commitment to the biosphere reserve concept by the governance authorities. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. XPS, TOF-SIMS, NEXAFS, and SPR Characterization of Nitrilotriacetic Acid-Terminated Self-Assembled Monloyers for Controllable Immobiliztion of Proteins

    International Nuclear Information System (INIS)

    Cheng, F.; Gamble, L.; Castner, D.

    2008-01-01

    For immobilization of proteins onto surfaces in a specific and controlled manner, it is important to start with a well-defined surface that contains specific binding sites surrounded by a nonfouling background. For immobilizing histidine-tagged (his-tagged) proteins, surfaces containing nitrilotriacetic acid (NTA) headgroups and oligo(ethylene glycol) (OEG) moieties are a widely used model system. The surface composition, structure, and reactivity of mixed NTA/OEG self-assembled monolayers (SAMs) on Au substrates were characterized in detail using X-ray photoelectron spectroscopy (XPS), near-edge X-ray absorption fine structure spectroscopy (NEXAFS), time-of-flight secondary ion mass spectrometry (TOF-SIMS), and surface plasmon resonance (SPR) biosensoring. XPS results for sequential adsorption of NTA thiols followed by OEG thiols showed that OEG molecules were incorporated into an incompletely formed NTA monolayer until a complete mixed SAM was formed. The surface concentration of NTA headgroups was estimated to be 0.9-1.3 molecule/nm2 in the mixed NTA/OEG monolayers, compared to 1.9 molecule/nm2 in pure NTA monolayers. Angle-dependent XPS indicated NTA headgroups were slightly reoriented toward an upright position after OEG incorporation, and polarization-dependent NEXAFS results indicated increased ordering of the alkane chains of the molecules. Nitrogen-containing and OEG-related secondary ion fragments from the TOF-SIMS experiments confirmed the presence of NTA headgroups and OEG moieties in the monolayers. A multivariate peak intensity ratio was developed for estimating the relative NTA concentration in the outermost (10 Angstroms ) of the monolayers. SPR measurements of a his-tagged, humanized anti-lysozyme variable fragment (HuLys Fv) immobilized onto Ni(II)-treated mixed NTA/OEG and pure NTA monolayers demonstrated the reversible, site-specific immobilization of his-tagged HuLys Fv (108-205 ng/cm2) with dissociation rates (koff) between 1.0 x 10-4 and 2

  14. Nuclear, uranium, reserves, sustainability, independence; Nucleaire, Uranium, reserves, durabilite, independance

    Energy Technology Data Exchange (ETDEWEB)

    Acket, C

    2007-06-15

    In order to evaluate the energy independence concerning the nuclear energy, the author takes the state of the art about the uranium. He details the fuel needs, the reserves on the base of the today available techniques, the reserves on the base of the future techniques and concludes positively on the energy independence for the nuclear. (A.L.B.)

  15. The Economics of NASA Mission Cost Reserves

    Science.gov (United States)

    Whitley, Sally; Shinn, Stephen

    2012-01-01

    Increases in NASA mission costs are well-noted but not well-understood, and there is little evidence that they are decreasing in frequency or amount over time. The need to control spending has led to analysis of the causes and magnitude of historical mission overruns, and many program control efforts are being implemented to attempt to prevent or mitigate the problem (NPR 7120). However, cost overruns have not abated, and while some direct causes of increased spending may be obvious (requirements creep, launch delays, directed changes, etc.), the underlying impetus to spend past the original budget may be more subtle. Gaining better insight into the causes of cost overruns will help NASA and its contracting organizations to avoid .them. This paper hypothesizes that one cause of NASA mission cost overruns is that the availability of reserves gives project team members an incentive to make decisions and behave in ways that increase costs. We theorize that the presence of reserves is a contributing factor to cost overruns because it causes organizations to use their funds less efficiently or to control spending less effectively. We draw a comparison to the insurance industry concept of moral hazard, the phenomenon that the presence of insurance causes insureds to have more frequent and higher insurance losses, and we attempt to apply actuarial techniques to quantifY the increase in the expected cost of a mission due to the availability of reserves. We create a theoretical model of reserve spending motivation by defining a variable ReserveSpending as a function of total reserves. This function has a positive slope; for every dollar of reserves available, there is a positive probability of spending it. Finally, the function should be concave down; the probability of spending each incremental dollar of reserves decreases progressively. We test the model against available NASA CADRe data by examining missions with reserve dollars initially available and testing whether

  16. Geologic technical assessment of the Stratton Ridge salt dome, Texas, for potential expansion of the U.S. strategic petroleum reserve.

    Energy Technology Data Exchange (ETDEWEB)

    Rautman, Christopher Arthur; Snider, Anna C.; Looff, Karl M. (Geologic Consultant, Lovelady, TX)

    2006-11-01

    The Stratton Ridge salt dome is a large salt diapir located only some ten miles from the currently active Strategic Petroleum Reserve Site at Bryan Mound, Texas. The dome is approximately 15 miles south-southwest of Houston. The Stratton Ridge salt dome has been intensively developed, in the desirable central portions, with caverns for both brine production and product storage. This geologic technical assessment indicates that the Stratton Ridge salt dome may be considered a viable, if less-than-desirable, candidate site for potential expansion of the Strategic Petroleum Reserve (SPR). Past development of underground caverns significantly limits the potential options for use by the SPR. The current conceptual design layout of proposed caverns for such an expansion facility is based upon a decades-old model of salt geometry, and it is unacceptable, according to this reinterpretation of salt dome geology. The easternmost set of conceptual caverns are located within a 300-ft buffer zone of a very major boundary shear zone, fault, or other structural feature of indeterminate origin. This structure transects the salt stock and subdivides it into an shallow western part and a deeper eastern part. In places, the distance from this structural boundary to the design-basis caverns is as little as 150 ft. A 300-ft distance from this boundary is likely to be the minimum acceptable stand-off, from both a geologic and a regulatory perspective. Repositioning of the proposed cavern field is possible, as sufficient currently undeveloped salt acreage appears to be available. However, such reconfiguration would be subject to limitations related to land-parcel boundaries and other existing infrastructure and topographic constraints. More broadly speaking, the past history of cavern operations at the Stratton Ridge salt dome indicates that operation of potential SPR expansion caverns at this site may be difficult, and correspondingly expensive. Although detailed information is

  17. Youth Problems on Indian Reservations.

    Science.gov (United States)

    Underhill, Ruth M., Ed.

    Juvenile delinquency was identified as the major problem affecting youth on Indian reservations. Causes for delinquency which were discussed included culture conflict, expectation of failure, unemployment, failure of homes and parents, discrimination, inadequate education, off-reservation schools, and alcoholism. Needs identified by tribal leaders…

  18. Can Creativity Predict Cognitive Reserve?

    Science.gov (United States)

    Palmiero, Massimiliano; Di Giacomo, Dina; Passafiume, Domenico

    2016-01-01

    Cognitive reserve relies on the ability to effectively cope with aging and brain damage by using alternate processes to approach tasks when standard approaches are no longer available. In this study, the issue if creativity can predict cognitive reserve has been explored. Forty participants (mean age: 61 years) filled out: the Cognitive Reserve…

  19. Detection and structural identification of dissolved organic matter in Antarctic glacial ice at natural abundance by SPR-W5-WATERGATE 1H NMR spectroscopy.

    Science.gov (United States)

    Pautler, Brent G; Simpson, André J; Simpson, Myrna J; Tseng, Li-Hong; Spraul, Manfred; Dubnick, Ashley; Sharp, Martin J; Fitzsimons, Sean J

    2011-06-01

    Dissolved organic matter (DOM) is ubiquitous in aquatic ecosystems and is derived from various inputs that control its turnover. Glaciers and ice sheets are the second largest water reservoir in the global hydrologic cycle, but little is known about glacial DOM composition or contributions to biogeochemical cycling. Here we employ SPR-W5-WATERGATE (1)H NMR spectroscopy to elucidate and quantify the chemical structures of DOM constituents in Antarctic glacial ice as they exist in their natural state (average DOC of 8 mg/L) without isolation or preconcentration. This Antarctic glacial DOM is predominantly composed of a mixture of small recognizable molecules differing from DOM in marine, lacustrine, and other terrestrial environments. The major constituents detected in three distinct types of glacial ice include lactic and formic acid, free amino acids, and a mixture of simple sugars and amino sugars with concentrations that vary between ice types. The detection of free amino acid and amino sugar monomer components of peptidoglycan within the ice suggests that Antarctic glacial DOM likely originates from in situ microbial activity. As these constituents are normally considered to be biologically labile (fast cycling) in nonglacial environments, accelerated glacier melt and runoff may result in a flux of nutrients into adjacent ecosystems.

  20. IMPLEMENTACIÓN DE UN SISTEMA DE PLANEACIÓN ESTRATÉGICA, BALANCE SCORECARD EN LA S.P.R.: NUEVA ALIANZA DE AGRICULTORES, FRANCISCO I. MADERO, COAHUILA.

    OpenAIRE

    Alvarado Martinez, Luis Felipe; Aguilar Valdes, Alfredo; Cabral Martell, Agustin; Alvarado Martinez, Tomas Everardo; de la Cruz à lvarez, Isaías

    2014-01-01

    Agricultural enterprises in Mexico have traditionally lacked administrative technical expertise, have been limited to use the minimum tools necessary to meet their fiscal commitments, and have neglected innovative techniques that would allow them to increase the agribusiness' profits. In this setting, the Balanced Scorecard applied to the S.P.R., R. L. de C. V: Nueva Alianza de Agricultores in the municipality of Francisco I. Madero, Coahuila is intended to establish a culture of Strategic Pl...

  1. Estimating Foreign Exchange Reserve Adequacy

    Directory of Open Access Journals (Sweden)

    Abdul Hakim

    2013-04-01

    Full Text Available Accumulating foreign exchange reserves, despite their cost and their impacts on other macroeconomics variables, provides some benefits. This paper models such foreign exchange reserves. To measure the adequacy of foreign exchange reserves for import, it uses total reserves-to-import ratio (TRM. The chosen independent variables are gross domestic product growth, exchange rates, opportunity cost, and a dummy variable separating the pre and post 1997 Asian financial crisis. To estimate the risky TRM value, this paper uses conditional Value-at-Risk (VaR, with the help of Glosten-Jagannathan-Runkle (GJR model to estimate the conditional volatility. The results suggest that all independent variables significantly influence TRM. They also suggest that the short and long run volatilities are evident, with the additional evidence of asymmetric effects of negative and positive past shocks. The VaR, which are calculated assuming both normal and t distributions, provide similar results, namely violations in 2005 and 2008.

  2. Cognitive Reserve Scale and ageing

    Directory of Open Access Journals (Sweden)

    Irene León

    2016-01-01

    Full Text Available The construct of cognitive reserve attempts to explain why some individuals with brain impairment, and some people during normal ageing, can solve cognitive tasks better than expected. This study aimed to estimate cognitive reserve in a healthy sample of people aged 65 years and over, with special attention to its influence on cognitive performance. For this purpose, it used the Cognitive Reserve Scale (CRS and a neuropsychological battery that included tests of attention and memory. The results revealed that women obtained higher total CRS raw scores than men. Moreover, the CRS predicted the learning curve, short-term and long-term memory, but not attentional and working memory performance. Thus, the CRS offers a new proxy of cognitive reserve based on cognitively stimulating activities performed by healthy elderly people. Following an active lifestyle throughout life was associated with better intellectual performance and positive effects on relevant aspects of quality of life.

  3. Fractional Reserve Banking: Some Quibbles

    OpenAIRE

    Bagus, Philipp; Howden, David

    2010-01-01

    We explore several unaddressed issues in George Selgin’s (1988) claim that the best monetary system to maintain monetary equilibrium is a fractional reserve free banking one. The claim that adverse clearing balances would limit credit expansion in a fractional reserve free banking system is more troublesome than previously reckoned. Both lengthened clearing periods and interbank agreements render credit expansion unrestrained. “The theory of free banking” confuses increases in money held with...

  4. 49 CFR 1106.6 - Reservation of Jurisdiction.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Reservation of Jurisdiction. 1106.6 Section 1106.6 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT... § 1106.6 Reservation of Jurisdiction. The Board reserves the right to require a SIP in cases other than...

  5. Management goals for wildlife reserves in grassveld and bushveld ...

    African Journals Online (AJOL)

    ... and therefore require control. A means of measuring the success of management is outlined. Keywords: condition; cover; fire; game reserves; genetic diversity; goals; management; management strategy; nature reserves; range; reserves; soil; south africa; species composition; species diversity; veld; veld condition; wildlife ...

  6. Reserve Retirement Equality: Treating Reserves Fairly While Saving Taxpayer Dollars

    Science.gov (United States)

    2010-06-09

    rata .121 For example, a Reserve who performs the equivalent of five years of active duty, will receive one-fourth the retired pay of his active duty...4,225 per month.124 But because reserve-retirement benefits are based on pro rata years of service, this officer’s years of service for retirement...purposes are 3,146 retirement points divided by 360.125 This results in 8.74 years pro rata years of service.126 His retirement benefits thus are

  7. Improved Effectiveness of Reserve Forces During Reserve Duty Training.

    Science.gov (United States)

    Treadaway, Harry H.

    The problem areas of motivation, job enrichment, recruiting, and retention are addressed from the viewpoint of the behavioral scientist. Special attention is given to relating job enrichment and motivation techniques, as successfully demonstrated in industry, to the United State Army Reserve. Research method utilized was a literature review…

  8. Cerebral correlates of cognitive reserve.

    Science.gov (United States)

    Whalley, Lawrence J; Staff, Roger T; Fox, Helen C; Murray, Alison D

    2016-01-30

    Cognitive reserve is a hypothetical concept introduced to explain discrepancies between severity of clinical dementia syndromes and the extent of dementia pathology. We examined cognitive reserve in a research programme that followed up a non-clinical sample born in 1921 or 1936 and IQ-tested age 11 years in 1932 or 1947. Structural MRI exams were acquired in about 50% of the sample from whom a subsample were recruited into an additional fMRI study. Here, we summarise findings from seven inter-related studies. These support an understanding of cognitive reserve as a balance between positive life course activity-driven experiences and the negative effects of brain pathologies including cerebrovascular disease and total and regional brain volume loss. Hypothesised structural equation models illustrate the relative causal effects of these positive and negative contributions. Cognitive reserve is considered in the context of choice of interventions to prevent dementia and the opposing effects of cerebrovascular disease and Alzheimer like brain appearances. Crown Copyright © 2015. Published by Elsevier Ireland Ltd. All rights reserved.

  9. Extractive reserves in Brazilian Amazonia

    Energy Technology Data Exchange (ETDEWEB)

    Fearnside, P.M (National Institute for Research in the Amazon, Manaus-Amazonas (Brazil))

    1989-06-01

    In 1985 an opportunity arose for maintaining tracts of Amazonian forest under sustainable use. Brazil's National Council of Rubber Tappers and the Rural Worker's Union proposed the creation of a set of reserves of a new type, called extractive reserves. The first six are being established in one of the Brazilian states most threatened by deforestatation. The creation of extractive reserves grants legal protection to forest land traditionally used by rubber tappers, Brazil-nut gatherers, and other extractivists. The term extrativismo (extractivism) in Brazil refers to removing nontimber forest products, such as latex, resins, and nuts, without felling the trees. Approximately 30 products are collected for commercial sale. Many more types of forest materials are gathered, for example as food and medicines, for the extractivists' own use. The reserve proposal is attractive for several reasons related to social problems. It allows the rubber tappers to continue their livelihood rather than be expelled by deforestation. However, it is unlikely that sufficient land will be set aside as extractive reserves to employ all the tappers. Displaced rubber tappers already swell the ranks of urban slum dwellers in Brazil's Amazonian cities, and they have become refugees to continue their profession in the forests of neighboring countries, such as Bolivia.

  10. Hydrocarbon Reserves: Abundance or Scarcity

    International Nuclear Information System (INIS)

    2005-01-01

    IFP and the OAPEC jointly organize a regular international seminar dealing with world oil-related problems appearing in the news. For the first time, this seminar has been opened to oil and gas company specialists, service companies, research centers and independents. This year's theme concerns oil and gas reserves: are they abundant or are we headed towards the shortages announced by some experts? This theme is especially topical in that: oil and gas currently meet two thirds of world energy needs and almost completely dominate the transport sector; the reserves declared by the OAPEC countries account for nearly half of world reserves; the price of a barrel of oil went through the roof in 2004; world energy demand is growing fast and alternative sources of energy are far from ready to take over from oil and gas in the next few decades. Since the reserves correspond to the volume it is technically and economically viable to produce, the seminar has, of course, dealt with the technical and economic questions that arise in connection with exploration and production, but it has also considered changes in the geopolitical context. Presentations by the leading companies of the OAPEC countries and by the IFP group were completed by presentation from the International Energy Agency (IEA), the United States Geological Survey (USGS), the IHS Energy Group, Total and Gaz de France. This document gathers the transparencies of the following presentations: Hydrocarbon reserves in OAPEC members countries: current and future (M. Al-Lababidi); Non OAPEC liquid reserves and production forecasts (Y. Mathieu); World oil and gas resources and production outlook (K. Chew); Global investments in the upstream (F. Birol); Total's policy in the oil and gas sector (C. de Margerie); Gaz de France's policy in the oil and gas sector (J. Abiteboul); NOC/IOC's opportunities in OPEC countries (I. Sandrea); Relationships between companies, countries and investors: How they may impact on the growth

  11. Hydrocarbon Reserves: Abundance or Scarcity

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    IFP and the OAPEC jointly organize a regular international seminar dealing with world oil-related problems appearing in the news. For the first time, this seminar has been opened to oil and gas company specialists, service companies, research centers and independents. This year's theme concerns oil and gas reserves: are they abundant or are we headed towards the shortages announced by some experts? This theme is especially topical in that: oil and gas currently meet two thirds of world energy needs and almost completely dominate the transport sector; the reserves declared by the OAPEC countries account for nearly half of world reserves; the price of a barrel of oil went through the roof in 2004; world energy demand is growing fast and alternative sources of energy are far from ready to take over from oil and gas in the next few decades. Since the reserves correspond to the volume it is technically and economically viable to produce, the seminar has, of course, dealt with the technical and economic questions that arise in connection with exploration and production, but it has also considered changes in the geopolitical context. Presentations by the leading companies of the OAPEC countries and by the IFP group were completed by presentation from the International Energy Agency (IEA), the United States Geological Survey (USGS), the IHS Energy Group, Total and Gaz de France. This document gathers the transparencies of the following presentations: Hydrocarbon reserves in OAPEC members countries: current and future (M. Al-Lababidi); Non OAPEC liquid reserves and production forecasts (Y. Mathieu); World oil and gas resources and production outlook (K. Chew); Global investments in the upstream (F. Birol); Total's policy in the oil and gas sector (C. de Margerie); Gaz de France's policy in the oil and gas sector (J. Abiteboul); NOC/IOC's opportunities in OPEC countries (I. Sandrea); Relationships between companies, countries and investors: How they may

  12. Viscoelastic modeling of highly hydrated laminin layers at homogeneous and nanostructured surfaces: quantification of protein layer properties using QCM-D and SPR.

    Science.gov (United States)

    Malmström, Jenny; Agheli, Hossein; Kingshott, Peter; Sutherland, Duncan S

    2007-09-11

    The adsorption of proteins at material surfaces is important in applications such as biomaterials, drug delivery, and diagnostics. The interaction of cells with artificial surfaces is mediated through adsorbed proteins, where the type of protein, amount, orientation, and conformation are of consequence for the cell response. Laminin, an important cell adhesive protein that is central in developmental biology, is studied by a combination of quartz crystal microbalance with dissipation (QCM-D) and surface plasmon resonance (SPR) to characterize the adsorption of laminin on surfaces of different surface chemistries. The combination of these two techniques allows for the determination of the thickness and effective density of the protein layer as well as the adsorbed mass and viscoelastic properties. We also evaluate the capacity of QCM-D to be used as a quantitative technique on a nanostructured surface, where protein is adsorbed specifically in a nanopattern exploiting PLL-g-PEG as a protein-resistant background. We show that laminin forms a highly hydrated protein layer with different characteristics depending on the underlying substrate. Using a combination of QCM-D and atomic force microscopy (AFM) data from nanostructured surfaces, we model laminin and antibody binding to nanometer-scale patches. A higher amount of laminin was found to adsorb in a thicker layer of a lower effective density in nanopatches compared to equivalent homogeneous surfaces. These results suggest that modeling of QCM-D data of soft viscoelastic layers arranged in nanopatterns may be applied where an independent measure of the "dry" mass is known.

  13. The incidental pulmonary nodule in a child. Part 1: recommendations from the SPR Thoracic Imaging Committee regarding characterization, significance and follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Westra, Sjirk J. [Massachusetts General Hospital, Division of Pediatric Radiology, Boston, MA (United States); Brody, Alan S. [Cincinnati Children' s Hospital Medical Center, Department of Radiology (CH-1), Cincinnati, OH (United States); Mahani, Maryam Ghadimi [University of Michigan Health System, Section of Pediatric Radiology, C. S. Mott Children' s Hospital Department of Radiology, Ann Arbor, MI (United States); Guillerman, R.P. [Texas Children' s Hospital, Department of Radiology, Houston, TX (United States); Hegde, Shilpa V. [Arkansas Children' s Hospital, Department of Radiology, Little Rock, AR (United States); Iyer, Ramesh S. [Seattle Children' s Hospital, Department of Radiology, Seattle, WA (United States); Lee, Edward Y. [Boston Children' s Hospital, Department of Pediatric Radiology, Boston, MA (United States); Newman, Beverley [Lucile Packard Children' s Hospital at Stanford University, Department of Radiology, Stanford, CA (United States); Podberesky, Daniel J. [Nemours Children' s Hospital, Department of Radiology, Orlando, FL (United States); Thacker, Paul G. [Medical University of South Carolina, Department of Radiology, Charleston, SC (United States)

    2015-05-01

    No guidelines are in place for the follow-up and management of pulmonary nodules that are incidentally detected on CT in the pediatric population. The Fleischner guidelines, which were developed for the older adult population, do not apply to children. This review summarizes the evidence collected by the Society for Pediatric Radiology (SPR) Thoracic Imaging Committee in its attempt to develop pediatric-specific guidelines. Small pulmonary opacities can be characterized as linear or as ground-glass or solid nodules. Linear opacities and ground-glass nodules are extremely unlikely to represent an early primary or metastatic malignancy in a child. In our review, we found a virtual absence of reported cases of a primary pulmonary malignancy presenting as an incidentally detected small lung nodule on CT in a healthy immune-competent child. Because of the lack of definitive information on the clinical significance of small lung nodules that are incidentally detected on CT in children, the management of those that do not have the typical characteristics of an intrapulmonary lymph node should be dictated by the clinical history as to possible exposure to infectious agents, the presence of an occult immunodeficiency, the much higher likelihood that the nodule represents a metastasis than a primary lung tumor, and ultimately the individual preference of the child's caregiver. Nodules appearing in children with a history of immune deficiency, malignancy or congenital pulmonary airway malformation should not be considered incidental, and their workup should be dictated by the natural history of these underlying conditions. (orig.)

  14. Revised results for geomechanical testing of MRIG-9 core for the potential SPR siting at the Richton Salt Dome.

    Energy Technology Data Exchange (ETDEWEB)

    Broome, Scott Thomas; Bauer, Stephen J.

    2010-02-01

    This report is a revision of SAND2009-0852. SAND2009-0852 was revised because it was discovered that a gage used in the original testing was mis-calibrated. Following the recalibration, all affected raw data were recalculated and re-presented. Most revised data is similar to, but slightly different than, the original data. Following the data re-analysis, none of the inferences or conclusions about the data or site relative to the SAND2009-0852 data have been changed. A laboratory testing program was developed to examine the mechanical behavior of salt from the Richton salt dome. The resulting information is intended for use in design and evaluation of a proposed Strategic Petroleum Reserve storage facility in that dome. Core obtained from the drill hole MRIG-9 was obtained from the Texas Bureau of Economic Geology. Mechanical properties testing included: (1) acoustic velocity wave measurements; (2) indirect tensile strength tests; (3) unconfined compressive strength tests; (4) ambient temperature quasi-static triaxial compression tests to evaluate dilational stress states at confining pressures of 725, 1450, 2175, and 2900 psi; and (5) confined triaxial creep experiments to evaluate the time-dependent behavior of the salt at axial stress differences of 4000 psi, 3500 psi, 3000 psi, 2175 psi and 2000 psi at 55 C and 4000 psi at 35 C, all at a constant confining pressure of 4000 psi. All comments, inferences, discussions of the Richton characterization and analysis are caveated by the small number of tests. Additional core and testing from a deeper well located at the proposed site is planned. The Richton rock salt is generally inhomogeneous as expressed by the density and velocity measurements with depth. In fact, we treated the salt as two populations, one clean and relatively pure (> 98% halite), the other salt with abundant (at times) anhydrite. The density has been related to the insoluble content. The limited mechanical testing completed has allowed us to

  15. Demand as Frequency Controlled Reserve

    DEFF Research Database (Denmark)

    Xu, Zhao; Østergaard, Jacob; Togeby, Mikael

    2011-01-01

    Relying on generation side alone is deemed insufficient to fulfill the system balancing needs for future Danish power system, where a 50% wind penetration is outlined by the government for year 2025. This paper investigates using the electricity demand as frequency controlled reserve (DFR) as a new...... balancing measure, which has a high potential and can provide many advantages. Firstly, the background of the research is reviewed, including conventional power system reserves and the electricity demand side potentials. Subsequently, the control logics and corresponding design considerations for the DFR...

  16. 77 FR 40253 - Reserve Account

    Science.gov (United States)

    2012-07-09

    .... The commentators represented Rural Development employees who work with the Multi-Family Housing Direct... their annual over-inflated tax bills and assessments. As a result, rent income funding that could be..., as rents cannot be raised to an amount that will cover all current and future reserve expenses...

  17. Demand as Frequency Controlled Reserve

    DEFF Research Database (Denmark)

    Xu, Zhao; Togeby, Mikael; Østergaard, Jacob

    This report summaries the research outcomes of the project ‘Demand as Frequency Controlled Reserve (DFR)’, which has received the support from Energinet.dk’s PSO program, Grant no. 2005-2-6380. The objective of this project is to investigate the technology of using electricity demands for providing...

  18. Uranium reserves and exploration activity

    International Nuclear Information System (INIS)

    Meehan, R.J.

    1975-01-01

    The strategy that ERDA plans to employ regarding resource appraisal is outlined. All types of uranium occurrences will be evaluated as sources of domestic ore reserves. Industry's exploration efforts will be compiled. These data will include information on land acquisition and costs, footage drilled and costs, estimates of exploration activities and expenditures, exploration for non-sandstone deposits, exploration in non-established areas, and foreign exploration plans and costs. Typical data in each of these areas are given

  19. Gas reserves, discoveries and production

    International Nuclear Information System (INIS)

    Saniere, A.

    2006-01-01

    Between 2000 and 2004, new discoveries, located mostly in the Asia/Pacific region, permitted a 71% produced reserve replacement rate. The Middle East and the offshore sector represent a growing proportion of world gas production Non-conventional gas resources are substantial but are not exploited to any significant extent, except in the United States, where they account for 30% of U.S. gas production. (author)

  20. Demand Response Spinning Reserve Demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Eto, Joseph H.; Nelson-Hoffman, Janine; Torres, Carlos; Hirth,Scott; Yinger, Bob; Kueck, John; Kirby, Brendan; Bernier, Clark; Wright,Roger; Barat, A.; Watson, David S.

    2007-05-01

    The Demand Response Spinning Reserve project is a pioneeringdemonstration of how existing utility load-management assets can providean important electricity system reliability resource known as spinningreserve. Using aggregated demand-side resources to provide spinningreserve will give grid operators at the California Independent SystemOperator (CAISO) and Southern California Edison (SCE) a powerful, newtool to improve system reliability, prevent rolling blackouts, and lowersystem operating costs.

  1. Indian Reserves: Canada's Developing Nations

    OpenAIRE

    Musto, Richard J.

    1990-01-01

    Indian reserves are the most visible reminder of the separation of aboriginal people from the rest of Canada and other Canadians. Illness patterns and social conditions in Native communities closely parallel those in developing nations. While they continue to have a large burden of infectious diseases, these groups also have an increased incidence of chronic and lifestyle diseases as well as environment-related conditions. Similarities can be seen in urban areas between immigrants from abroad...

  2. 78 FR 70542 - Reserve Forces Policy Board (RFPB); Notice of Federal Advisory Committee Meeting

    Science.gov (United States)

    2013-11-26

    ... identification of Defense Support of Civilian Authorities requirements. The Subcommittee on Personnel plans to..., issues impacting reserve organizations, the right balance of Active and Reserve Component forces, and...

  3. Foreign Exchange Reserves: Bangladesh Perspective

    Directory of Open Access Journals (Sweden)

    Md Zahangir Alam

    2013-10-01

    Full Text Available This study is about foreign exchangereserves of Bangladesh. The mainpurpose of this study is to the influence of exchange rates on foreign exchangereserves to the Bangladesh context.  Both the primary and secondary data has been used inthis study. The primary data has been collected through a structuredquestionnaire from 50 respondents. The secondary data, namely Bangladeshforeign exchange reserves (FER, Bangladesh current account balance (CAB,Bangladesh capital andfinancial account balance (CFAB, and BDT/USD exchange rates (ER.  This study covers yearly data from July 01,1996 to June 30, 2005 and quarterly data from July 01, 2005 to June 30, 2012. Findingsof this study shows that out of the selected 16 factors affecting foreignexchange reserves, exchange rates occupy the first position, weighted averagescore (WAS being 4.56. Foreign exchange reserves (FER and current accountbalance (CAB have increased by 502.9087% and 1451.218%,whereas capital and financial account (CFAB has decreased by -649.024% on June30, 2012 compared to June 30, 1997. The influence of other factors heldconstant, as ER changes by 285.6894 units due to one unit change in FER, onaverage in the same direction which represents that ER has positive effect on theFER and this relationship is statistically significant.  62.1526 percentof the variation in FER is explained by ER. The outcomes of Breusch-Godfrey test (LM test, ARCHtest, and the Normality test are that there is a serial correlation among residuals, the variance of residuals is notconstant, and the residuals are not normally distributed.

  4. Brain reserve and cognitive reserve in multiple sclerosis

    Science.gov (United States)

    Rocca, Maria A.; Leavitt, Victoria M.; Riccitelli, Gianna; Comi, Giancarlo; DeLuca, John; Filippi, Massimo

    2013-01-01

    Objective: We first tested the brain reserve (BR) hypothesis in multiple sclerosis (MS) by examining whether larger maximal lifetime brain volume (MLBV; determined by genetics) protects against disease-related cognitive impairment, and then investigated whether cognitive reserve (CR) gained through life experience (intellectually enriching leisure activities) protects against cognitive decline independently of MLBV (BR). Methods: Sixty-two patients with MS (41 relapsing-remitting MS, 21 secondary progressive MS) received MRIs to estimate BR (MLBV, estimated with intracranial volume [ICV]) and disease burden (T2 lesion load; atrophy of gray matter, white matter, thalamus, and hippocampus). Early-life cognitive leisure was measured as a source of CR. We assessed cognitive status with tasks of cognitive efficiency and memory. Hierarchical regressions were used to investigate whether higher BR (ICV) protects against cognitive impairment, and whether higher CR (leisure) independently protects against cognitive impairment over and above BR. Results: Cognitive status was positively associated with ICV (R2 = 0.066, p = 0.017). An ICV × disease burden interaction (R2 = 0.050, p = 0.030) revealed that larger ICV attenuated the impact of disease burden on cognition. Controlling for BR, higher education (R2 = 0.047, p = 0.030) and leisure (R2 = 0.090, p = 0.001) predicted better cognition. A leisure × disease burden interaction (R2 = 0.037, p = 0.030) showed that leisure independently attenuated the impact of disease burden on cognition. Follow-up analyses revealed that BR protected against cognitive inefficiency, not memory deficits, whereas CR was more protective against memory deficits than cognitive inefficiency. Conclusion: We provide evidence of BR in MS, and show that CR independently protects against disease-related cognitive decline over and above BR. Lifestyle choices protect against cognitive impairment independently of genetic factors outside of one's control

  5. Effects of different international fiscal systems on reserves reporting

    International Nuclear Information System (INIS)

    McMichael, C.L.

    1996-01-01

    The effects of international fiscal systems on oil and gas reserves evaluation and reporting, was reviewed. The movement in reserves estimates with changing technical, political and economic conditions, was described. Difficulties associated with the evaluation and booking of reserves is largely due to the confusing duplication of terms. For example, explorationists refer to reserves as an undrilled prospect, while engineers refer to them as producing property. The financial analyst refers to reserves of a company, while governments refer to the reserves of the country. The importance of defining reserves with full knowledge of the specific regulations that govern the reporting of reserves externally, and the internal reporting requirements for business planning purposes, was stressed. 2 refs

  6. Hexahedral Finite Element Mesh Capturing Realistic Geometries of Bayou Choctaw Strategic Petroleum Reserve

    Science.gov (United States)

    Park, B. Y.; Roberts, B. L.; Sobolik, S. R.

    2016-12-01

    The U.S. Strategic Petroleum Reserve (SPR) stores crude oil in 60 caverns located at four sites located along the Gulf Coast. As a matter of normal operation of caverns in a salt dome, the continuous mechanical creep of salt, along with the change in internal cavern and casing pressure due to cavern closure and fluid exchanges, impose several mechanical conditions on the skin, well, and casing of a cavern that could potentially create damage. Sandia, on behalf of DOE, is evaluating the structural integrity of the salt surrounding existing caverns in the Bayou Choctaw (BC) salt dome in Louisiana. In reality, the geometry, spacing, and depths of the caverns are irregular. It is not easy to realize the naturally and artificially formed cavern and salt dome for numerical analysis. It is harder to convert the geometries into the meshed mass consisting of only hexahedral finite elements. A three-dimensional (3D) finite element mesh capturing realistic geometries of the Bayou Choctaw site has been constructed using the seismic and sonar survey data obtained from the field (see Figures below). The mesh consists of hexahedral elements because the salt constitutive model is coded using hexahedral elements. Techniques to reduce the number of elements as much as possible to save on computer run time while maintaining computational accuracy are also developed. These methodologies could also be applied to construct computational meshes for the Big Hill, Bryan Mound, and West Hackberry SPR sites. The methodology could be applied to the complicated shape masses for not only various civil and geological structures but also biological applications such as artificial limbs. The newly developed mesh is expected to provide more accurate solutions of geotechnical concerns that arise due to the close proximity of the caverns to each other or to the edge of salt. Also, there are nine abandoned caverns, one of which is believed to be in a quasi-stable condition. Stability issues for these

  7. Indian reservation safety improvement program : a methodology and case study.

    Science.gov (United States)

    2015-11-01

    Improving roadway safety on Indian reservations requires a comprehensive approach. Limited : resources, lack of crash data, and few cross-jurisdictions coordination has made it difficult for : Native American communities to address their roadway safe...

  8. 40 CFR 80.575-80.579 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Motor Vehicle Diesel Fuel; Nonroad, Locomotive, and Marine Diesel Fuel; and ECA Marine Fuel Labeling Requirements §§ 80.575-80.579 [Reserved] Sampling and Testing ...

  9. 29 CFR 1910.336-1910.360 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR OCCUPATIONAL SAFETY AND HEALTH STANDARDS Electrical Safety-Related Work Practices §§ 1910.336-1910.360 [Reserved] Safety-Related Maintenance Requirements ...

  10. Individual Ready Reserve: It's Relevance in Supporting the Long War

    National Research Council Canada - National Science Library

    Chisholm, Shelley A

    2008-01-01

    ... in sustaining personnel readiness while supporting on going operations. In response to meeting these personnel readiness concerns, the Army Reserve will require the call-up of Soldiers currently serving in the IRR...

  11. Z' reservation at LEP2

    CERN Document Server

    Montagna, G.; Piccinini, F.; Renard, F.M.; Verzegnassi, C.

    1995-01-01

    We consider the possibility that one extra Z\\equiv Z' exists with arbitrary mass and fermion couplings that do not violate (charged) lepton universality. We show that, in such a situation, a functional relationship is generated between the \\underline{deviations} from the SM values of three leptonic observables of two-fermion production at future e^+e^- colliders that is completely independent of the values of the Z' mass and couplings. This selects a certain region in the 3-d space of the deviations that is \\underline{characteristic} of the model (Z' "reservation"). As a specific and relevant example, we show the picture that would emerge at LEP2 under realistic experimental conditions.

  12. The Ecological Reserve: Towards a common understanding for river ...

    African Journals Online (AJOL)

    The legal requirement for an Ecological Reserve established in South Africa\\'s water law is commonly regarded by stakeholders as being in direct competition with the needs of humans. This has resulted in much debate and varying interpretations of the meaning and purpose of the Ecological Reserve. However, the ...

  13. 47 CFR 80.860 - Reserve power supply.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Reserve power supply. 80.860 Section 80.860 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Technical Equipment Requirements for Cargo Vessels Not Subject to Subpart W § 80.860 Reserve power supply. (a) When the...

  14. 47 CFR 80.917 - Reserve power supply.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Reserve power supply. 80.917 Section 80.917 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Compulsory Radiotelephone Installations for Small Passenger Boats § 80.917 Reserve power supply. (a) The requirements of...

  15. 47 CFR 80.965 - Reserve power supply.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Reserve power supply. 80.965 Section 80.965 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Radiotelephone Installation Required for Vessels on the Great Lakes § 80.965 Reserve power supply. (a) Each passenger...

  16. 30 CFR 285.311-285.314 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false [Reserved] 285.311-285.314 Section 285.311-285.314 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE... §§ 285.311-285.314 [Reserved] Financial Requirements for ROW Grants and RUE Grants ...

  17. 25 CFR 151.11 - Off-reservation acquisitions.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Off-reservation acquisitions. 151.11 Section 151.11 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LAND ACQUISITIONS § 151.11 Off-reservation acquisitions. The Secretary shall consider the following requirements in evaluating tribal...

  18. 25 CFR 141.10 - License fees for reservation businesses.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false License fees for reservation businesses. 141.10 Section 141.10 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES BUSINESS PRACTICES ON THE NAVAJO, HOPI AND ZUNI RESERVATIONS Licensing Requirements and Procedures § 141.10 License...

  19. 25 CFR 141.8 - License period for reservation businesses.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false License period for reservation businesses. 141.8 Section 141.8 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES BUSINESS PRACTICES ON THE NAVAJO, HOPI AND ZUNI RESERVATIONS Licensing Requirements and Procedures § 141.8 License...

  20. The development and validation of a sensitive, dual-flow cell, SPR-based biosensor immunoassay for the detection, semi-quantitation, and characterization of antibodies to darbepoetin alfa and epoetin alfa in human serum.

    Science.gov (United States)

    Mytych, Daniel T; La, Stephon; Barger, Troy; Ferbas, John; Swanson, Steven J

    2009-02-20

    A surface plasmon resonance (SPR)-based biosensor immunoassay was developed and validated using the Biacore 3000 instrument to detect, semi-quantitate, and characterize serum antibodies against darbepoetin alfa (Aranesp) and epoetin alfa (EPOGEN). In this sensitive, dual-flow cell assay, epoetin alfa and darbepoetin alfa are covalently immobilized onto consecutive flow cells of a carboxymethyl dextran-coated sensor chip. Diluted human serum samples are injected sequentially over both surfaces. The binding of serum antibodies to the immobilized proteins are detected and recorded in real time based on the principles of SPR. Furthermore, antibody binding is confirmed with a secondary anti-human immunoglobulin antibody. Positive samples are further characterized to determine the relative concentration of the antibodies using an affinity-purified, rabbit anti-epoetin alfa antibody as a reference control. The assay can detect 80ng/ml and 100ng/ml of antibody to epoetin alfa and darbepoetin alfa, respectively. The dynamic range of the assay is from 0.078microg/ml to 10microg/ml using a rabbit antibody with demonstrated accuracy and intra- and inter-assay precision. Approximately 80 serum samples can be analyzed on each sensor chip while maintaining a stable baseline and consistent immunological reactivity. The analysis of serum samples from subjects administered with epoetin alfa or darbepoetin alfa provided evidence that the assay can detect varying concentrations of antibodies of different off rates, isotypes, and IgG subclasses.

  1. Essays in the California electricity reserves markets

    Science.gov (United States)

    Metaxoglou, Konstantinos

    This dissertation examines inefficiencies in the California electricity reserves markets. In Chapter 1, I use the information released during the investigation of the state's electricity crisis of 2000 and 2001 by the Federal Energy Regulatory Commission to diagnose allocative inefficiencies. Building upon the work of Wolak (2000), I calculate a lower bound for the sellers' price-cost margins using the inverse elasticities of their residual demand curves. The downward bias in my estimates stems from the fact that I don't account for the hierarchical substitutability of the reserve types. The margins averaged at least 20 percent for the two highest quality types of reserves, regulation and spinning, generating millions of dollars in transfers to a handful of sellers. I provide evidence that the deviations from marginal cost pricing were due to the markets' high concentration and a principal-agent relationship that emerged from their design. In Chapter 2, I document systematic differences between the markets' day- and hour-ahead prices. I use a high-dimensional vector moving average model to estimate the premia and conduct correct inferences. To obtain exact maximum likelihood estimates of the model, I employ the EM algorithm that I develop in Chapter 3. I uncover significant day-ahead premia, which I attribute to market design characteristics too. On the demand side, the market design established a principal-agent relationship between the markets' buyers (principal) and their supervisory authority (agent). The agent had very limited incentives to shift reserve purchases to the lower priced hour-ahead markets. On the supply side, the market design raised substantial entry barriers by precluding purely speculative trading and by introducing a complicated code of conduct that induced uncertainty about which actions were subject to regulatory scrutiny. In Chapter 3, I introduce a state-space representation for vector autoregressive moving average models that enables

  2. Seamless Requirements

    OpenAIRE

    Naumchev, Alexandr; Meyer, Bertrand

    2017-01-01

    Popular notations for functional requirements specifications frequently ignore developers' needs, target specific development models, or require translation of requirements into tests for verification; the results can give out-of-sync or downright incompatible artifacts. Seamless Requirements, a new approach to specifying functional requirements, contributes to developers' understanding of requirements and to software quality regardless of the process, while the process itself becomes lighter...

  3. Digital radiographic assessment of coronary flow reserve

    International Nuclear Information System (INIS)

    Vogel, R.A.

    1985-01-01

    A method for measuring relative changes in regional blood flow using digital radiographic enhancement of selective coronary arteriography. Coronary flow reserve is measured in individual arterial distributions using the washin ratio of contrast appearance time under baseline and hyperemic conditions. Information is quantitatively presented in functional (parametric) image format. These images, termed contrast medium appearance pictures (CMAP), depict the transit of contrast through the arterial, myocardial and early venous stages. This process can be divided into three general phases: data acquisition, CMAP formation and CMAP analysis. The technique has evolved over its development period from a cine film-based technology which required substantial processing time to a real-time digital radiographic technique

  4. Fundamental Drivers of the Cost and Price of Operating Reserves

    Energy Technology Data Exchange (ETDEWEB)

    Hummon, Marissa [National Renewable Energy Lab. (NREL), Golden, CO (United States); Denholm, Paul [National Renewable Energy Lab. (NREL), Golden, CO (United States); Jorgenson, Jennie [National Renewable Energy Lab. (NREL), Golden, CO (United States); Palchak, David [National Renewable Energy Lab. (NREL), Golden, CO (United States); Kirby, Brendan [Kirby Consultant; Ma, Ookie [U.S. Department of Energy, Washington, DC (United States)

    2013-07-01

    Operating reserves impose a cost on the electric power system by forcing system operators to keep partially loaded spinning generators available for responding to system contingencies variable demand. In many regions of the United States, thermal power plants provide a large fraction of the operating reserve requirement. Alternative sources of operating reserves, such as demand response and energy storage, may provide more efficient sources of these reserves. However, to estimate the potential value of these services, the cost of reserve services under various grid conditions must first be established. This analysis used a commercial grid simulation tool to evaluate the cost and price of several operating reserve services, including spinning contingency reserves and upward regulation reserves. These reserve products were evaluated in a utility system in the western United States, considering different system flexibilities, renewable energy penetration, and other sensitivities. The analysis demonstrates that the price of operating reserves depend highly on many assumptions regarding the operational flexibility of the generation fleet, including ramp rates and the fraction of fleet available to provide reserves.

  5. Classification of uranium reserves/resources

    International Nuclear Information System (INIS)

    1998-08-01

    Projections of future availability of uranium to meet present and future nuclear power requirements depend on the reliability of uranium resource estimates. Lack of harmony of the definition of the different classes of uranium reserves and resources between countries makes the compilation and analysis of such information difficult. The problem was accentuated in the early 1990s with the entry of uranium producing countries from the former Soviet Union, eastern Europe and China into the world uranium supply market. The need for an internationally acceptable reserve/resource classification system and terminology using market based criteria is therefore obvious. This publication was compiled from participant's contributions and findings of the Consultants Meetings on Harmonization of Uranium Resource Assessment Concepts held in Vienna from 22 to 25 June 1992, and two Consultants Meetings on the Development of a More Meaningful Classification of Uranium Resources held in Kiev, Ukraine on 24-26 April 1995 and 20-23 August 1996. This document includes 11 contributions, summary, list of participants of the Consultants Meetings. Each contribution has been indexed and provided with an abstract

  6. Federal Reserve System Semiannual Regulatory Agenda

    Science.gov (United States)

    2010-12-20

    ... [The Regulatory Plan and Unified Agenda of Federal Regulatory and Deregulatory Actions] [Federal Reserve System Semiannual Regulatory Agenda ] Part XXI Federal Reserve System Semiannual Regulatory Agenda... Flexibility Agenda AGENCY: Board of Governors of the Federal Reserve System. ACTION: Semiannual regulatory...

  7. National Guard and Reserves: Air Force Needs to Consistently Assess Personnel Requirements to Appropriately Size Its Headquarters Reserve Components

    Science.gov (United States)

    2016-08-01

    Columbia, Puerto Rico , the Virgin Islands, and Guam also have National Guard forces that can be activated for federal missions. Over the same period...the 54 Joint Force Headquarters – State, located in each state, the District of Columbia, Puerto Rico , the Virgin Islands, and Guam, is comprised of... currency reviews be performed in conjunction with the biannual application of personnel assessment standards. Officials from the Office of the

  8. 24 CFR 891.605 - Replacement reserve.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Replacement reserve. 891.605... 8 Assistance § 891.605 Replacement reserve. (a) Establishment of reserve. The Borrower shall establish and maintain a replacement reserve to aid in funding extraordinary maintenance, and repair and...

  9. 24 CFR 891.405 - Replacement reserve.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Replacement reserve. 891.405....405 Replacement reserve. (a) Establishment of reserve. The Owner shall establish and maintain a replacement reserve to aid in funding extraordinary maintenance and repair and replacement of capital items...

  10. Cognitive Reserve: Implications for Assessment and Intervention

    OpenAIRE

    Stern, Yaakov

    2013-01-01

    The concept of reserve is used to explain the observation that some individuals function better than others in the presence of brain pathology. This paper reviews the concept of reserve from its theoretical basis to the implication of reserve for clinical practice. A distinction between brain reserve, referring to individual differences in the anatomic substrate, and cognitive reserve, referring to differences in the flexibility or adaptivity of cognitive networks, is useful. Epidemiologic ev...

  11. Investigação numérica do desempenho de um sensor de fibra ótica de índice de refração, baseado em SPR e utilizando COMSOL multiphysics

    OpenAIRE

    Santos, Diego Felipe de Nóbrega dos

    2013-01-01

    Esta tese é dedicada aos sensores de fibra ótica especificamente aos sensores baseados no fenómeno de ressonância de plasmão de superfície, SPR (Surface Plasmon Resonance), gerados em fibras óticas com configuração do tipo “D”, para aplicação em sensores refratométricos. Numa primeira parte desta dissertação são descritos os aspetos teóricos fundamentais para a compreensão dos fenómenos de ressonância de plasmões de superfície e a sua utilização em sistemas sensores. Estes f...

  12. High-resolution paleoclimatology of the Santa Barbara Basin during the Medieval Climate Anomaly and early Little Ice Age based on diatom and silicoflagellate assemblages in Kasten core SPR0901-02KC

    Science.gov (United States)

    Barron, John A.; Bukry, David B.; Hendy, Ingrid L.

    2015-01-01

    Diatom and silicoflagellate assemblages documented in a high-resolution time series spanning 800 to 1600 AD in varved sediment recovered in Kasten core SPR0901-02KC (34°16.845’ N, 120°02.332’ W, water depth 588 m) from the Santa Barbara Basin (SBB) reveal that SBB surface water conditions during the Medieval Climate Anomaly (MCA) and the early part of the Little Ice Age (LIA) were not extreme by modern standards, mostly falling within one standard deviation of mean conditions during the pre anthropogenic interval of 1748 to 1900. No clear differences between the character of MCA and the early LIA conditions are apparent. During intervals of extreme droughts identified by terrigenous proxy scanning XRF analyses, diatom and silicoflagellate proxies for coastal upwelling typically exceed one standard deviation above mean values for 1748-1900, supporting the hypothesis that droughts in southern California are associated with cooler (or La Niña-like) sea surface temperatures (SSTs). Increased percentages of diatoms transported downslope generally coincide with intervals of increased siliciclastic flux to the SBB identified by scanning XRF analyses. Diatom assemblages suggest only two intervals of the MCA (at ~897 to 922 and ~1151 to 1167) when proxy SSTs exceeded one standard deviation above mean values for 1748 to 1900. Conversely, silicoflagellates imply extreme warm water events only at ~830 to 860 (early MCA) and ~1360 to 1370 (early LIA) that are not supported by the diatom data. Silicoflagellates appear to be more suitable for characterizing average climate during the 5 to 11 year-long sample intervals studied in the SPR0901-02KC core than diatoms, probably because diatom relative abundances may be dominated by seasonal blooms of a particular year.

  13. Improving Medical and Dental Readiness in the Reserve Components

    Science.gov (United States)

    2012-01-01

    Dental sealants , remineralization therapy, and chewing of xylitol gum are effective for preventing and reversing early signs of dental decay. The...Improving Medical and Dental Readiness in the Reserve Components A s an integral part of the U.S. military, the reserve components (RCs) are...limit their ability to carry out their duties, whether in garrison or deployed. Medically ready reservists require less medical and dental support

  14. Designing connected marine reserves in the face of global warming.

    Science.gov (United States)

    Álvarez-Romero, Jorge G; Munguía-Vega, Adrián; Beger, Maria; Del Mar Mancha-Cisneros, Maria; Suárez-Castillo, Alvin N; Gurney, Georgina G; Pressey, Robert L; Gerber, Leah R; Morzaria-Luna, Hem Nalini; Reyes-Bonilla, Héctor; Adams, Vanessa M; Kolb, Melanie; Graham, Erin M; VanDerWal, Jeremy; Castillo-López, Alejandro; Hinojosa-Arango, Gustavo; Petatán-Ramírez, David; Moreno-Baez, Marcia; Godínez-Reyes, Carlos R; Torre, Jorge

    2018-02-01

    Marine reserves are widely used to protect species important for conservation and fisheries and to help maintain ecological processes that sustain their populations, including recruitment and dispersal. Achieving these goals requires well-connected networks of marine reserves that maximize larval connectivity, thus allowing exchanges between populations and recolonization after local disturbances. However, global warming can disrupt connectivity by shortening potential dispersal pathways through changes in larval physiology. These changes can compromise the performance of marine reserve networks, thus requiring adjusting their design to account for ocean warming. To date, empirical approaches to marine prioritization have not considered larval connectivity as affected by global warming. Here, we develop a framework for designing marine reserve networks that integrates graph theory and changes in larval connectivity due to potential reductions in planktonic larval duration (PLD) associated with ocean warming, given current socioeconomic constraints. Using the Gulf of California as case study, we assess the benefits and costs of adjusting networks to account for connectivity, with and without ocean warming. We compare reserve networks designed to achieve representation of species and ecosystems with networks designed to also maximize connectivity under current and future ocean-warming scenarios. Our results indicate that current larval connectivity could be reduced significantly under ocean warming because of shortened PLDs. Given the potential changes in connectivity, we show that our graph-theoretical approach based on centrality (eigenvector and distance-weighted fragmentation) of habitat patches can help design better-connected marine reserve networks for the future with equivalent costs. We found that maintaining dispersal connectivity incidentally through representation-only reserve design is unlikely, particularly in regions with strong asymmetric patterns of

  15. The role of new technologies in expanding useful coal reserves

    Energy Technology Data Exchange (ETDEWEB)

    Sligar, J. [Pacific Power, Sydney, NSW (Australia)

    1995-12-31

    The range of new high efficiency coal utilisation technologies for power generation will have a marked effect in increasing marketable coal reserves from world sources as the technologies are integrated into new and retrofitted power stations. These technologies are substantially more efficient than pulverised coal technology; so if marketable coal reserves are viewed as energy reserves there will be an increase of at least 28% due to this factor alone. In addition, the new technologies use coals with different sets of properties to present internationally traded coals. In many cases reserves of these coals exist but are not presently included in reserves for power generation but which will need to be included in the future. These changes, which require a reassessment of marketable resources for the reliable generation of cheap and environmentally friendly energy and generally extend coal resources by a conservative 33%.

  16. Reactive Power Compensation Method Considering Minimum Effective Reactive Power Reserve

    Science.gov (United States)

    Gong, Yiyu; Zhang, Kai; Pu, Zhang; Li, Xuenan; Zuo, Xianghong; Zhen, Jiao; Sudan, Teng

    2017-05-01

    According to the calculation model of minimum generator reactive power reserve of power system voltage stability under the premise of the guarantee, the reactive power management system with reactive power compensation combined generator, the formation of a multi-objective optimization problem, propose a reactive power reserve is considered the minimum generator reactive power compensation optimization method. This method through the improvement of the objective function and constraint conditions, when the system load growth, relying solely on reactive power generation system can not meet the requirement of safe operation, increase the reactive power reserve to solve the problem of minimum generator reactive power compensation in the case of load node.

  17. VAr reserve concept applied to a wind power plant

    DEFF Research Database (Denmark)

    Martinez, Jorge; Kjær, Philip C.; Rodriguez, Pedro

    2011-01-01

    to wind power plants. This paper proposes two different VAr reserve control strategies for a wind power plant. The amount of dynamic VAr available most of the operation time, makes the wind power plant (WPP) a good candidate to include a VAr reserve management system. Two different ways of implementing...... a VAr management system are proposed and analyzed. Such a reactive power reserve may be provided by the wind power plant since the amount of reactive power installed for most active power working points exceeds the demand required by the grid operator. Basically, this overrated reactive power capacity...

  18. Assessment of secondary aluminum reserves of nations

    DEFF Research Database (Denmark)

    Maung, Kyaw Nyunt; Yoshida, Tomoharu; Liu, Gang

    2017-01-01

    A classification framework of the secondary resources was applied to evaluate the framework's applicability and to assess secondary aluminum reserves for 19 countries. Estimated amounts of secondary aluminum reserves in 2010 were 85 million tonnes in the United States, 65 million tonnes in China......, 29 million tonnes in Japan, and 413 million tonnes globally. For the United States, its secondary reserves are larger than its primary reserves, although the global primary reserves (28,000 million tonnes) are much larger than the estimated secondary reserves. Considerable amounts of secondary...

  19. Cognitive Reserve: Implications for Assessment and Intervention

    Science.gov (United States)

    Stern, Yaakov

    2014-01-01

    The concept of reserve is used to explain the observation that some individuals function better than others in the presence of brain pathology. This paper reviews the concept of reserve from its theoretical basis to the implication of reserve for clinical practice. A distinction between brain reserve, referring to individual differences in the anatomic substrate, and cognitive reserve, referring to differences in the flexibility or adaptivity of cognitive networks, is useful. Epidemiologic evidence indicates that a set of life exposures including higher educational and occupational attainment, and engaging in leisure activities is associated with a lower risk of incident dementia, suggesting that these life exposures may enhance cognitive reserve. This provides a basis for controlled clinical studies can test specific exposures that may enhance reserve. The concept of cognitive reserve also has important implications for clinical practice in terms of diagnosis and prognosis. PMID:23941972

  20. Clipboard: Unraveling the mystery of cognitive reserve

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 40; Issue 2. Clipboard : Unraveling the mystery of cognitive reserve ... Keywords. Aging; Alzheimer's; bilingualism; cognitive reserve; dementia; Down's; education; enrichment; environment; learning; long term potentiation; LTP; memory; neuroepigenetics; plasticity ...

  1. Transforming the Reserve Component: Four Essays

    National Research Council Canada - National Science Library

    Binnendijk, Hans; Baranick, Michael J; Bell, Raymond E., Jr; Cordero, Gina; Duncan, Stephen M; Holshek, Christopher; Wentz, Larry

    2005-01-01

    This volume contains four essays on various aspects of the Reserve Component. We publish it at a time when Reserves are serving overseas at historically high rates and when new missions like homeland security demand their attention...

  2. 5 CFR 330.610 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false [Reserved] 330.610 Section 330.610 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS RECRUITMENT, SELECTION, AND... Employees § 330.610 [Reserved] ...

  3. 5 CFR 330.603 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false [Reserved] 330.603 Section 330.603 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS RECRUITMENT, SELECTION, AND... Employees § 330.603 [Reserved] ...

  4. Calculating Launch Vehicle Flight Performance Reserve

    Science.gov (United States)

    Hanson, John M.; Pinson, Robin M.; Beard, Bernard B.

    2011-01-01

    This paper addresses different methods for determining the amount of extra propellant (flight performance reserve or FPR) that is necessary to reach orbit with a high probability of success. One approach involves assuming that the various influential parameters are independent and that the result behaves as a Gaussian. Alternatively, probabilistic models may be used to determine the vehicle and environmental models that will be available (estimated) for a launch day go/no go decision. High-fidelity closed-loop Monte Carlo simulation determines the amount of propellant used with each random combination of parameters that are still unknown at the time of launch. Using the results of the Monte Carlo simulation, several methods were used to calculate the FPR. The final chosen solution involves determining distributions for the pertinent outputs and running a separate Monte Carlo simulation to obtain a best estimate of the required FPR. This result differs from the result obtained using the other methods sufficiently that the higher fidelity is warranted.

  5. Reserving by detailed conditioning on individual claim

    Science.gov (United States)

    Kartikasari, Mujiati Dwi; Effendie, Adhitya Ronnie; Wilandari, Yuciana

    2017-03-01

    The estimation of claim reserves is an important activity in insurance companies to fulfill their liabilities. Recently, reserving method of individual claim have attracted a lot of interest in the actuarial science, which overcome some deficiency of aggregated claim method. This paper explores the Reserving by Detailed Conditioning (RDC) method using all of claim information for reserving with individual claim of liability insurance from an Indonesian general insurance company. Furthermore, we compare it to Chain Ladder and Bornhuetter-Ferguson method.

  6. Poverty and corruption compromise tropical forest reserves.

    Science.gov (United States)

    Wright, S Joseph; Sanchez-Azofeifa, G Arturo; Portillo-Quintero, Carlos; Davies, Diane

    2007-07-01

    We used the global fire detection record provided by the satellite-based Moderate Resolution Imaging Spectroradiometer (MODIS) to determine the number of fires detected inside 823 tropical and subtropical moist forest reserves and for contiguous buffer areas 5, 10, and 15 km wide. The ratio of fire detection densities (detections per square kilometer) inside reserves to their contiguous buffer areas provided an index of reserve effectiveness. Fire detection density was significantly lower inside reserves than in paired, contiguous buffer areas but varied by five orders of magnitude among reserves. The buffer: reserve detection ratio varied by up to four orders of magnitude among reserves within a single country, and median values varied by three orders of magnitude among countries. Reserves tended to be least effective at reducing fire frequency in many poorer countries and in countries beset by corruption. Countries with the most successful reserves include Costa Rica, Jamaica, Malaysia, and Taiwan and the Indonesian island of Java. Countries with the most problematic reserves include Cambodia, Guatemala, Paraguay, and Sierra Leone and the Indonesian portion of Borneo. We provide fire detection density for 3964 tropical and subtropical reserves and their buffer areas in the hope that these data will expedite further analyses that might lead to improved management of tropical reserves.

  7. 24 CFR 880.602 - Replacement reserve.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Replacement reserve. 880.602... Replacement reserve. (a) A replacement reserve must be established and maintained in an interest-bearing account to aid in funding extraordinary maintenance and repair and replacement of capital items. (1) Part...

  8. Reserve evaluation of minerals at NUCLEBRAS

    International Nuclear Information System (INIS)

    Marques, J.P.M.; Guerra, P.A.G.; Vinha, C.A.G. da

    1980-10-01

    The method used for the reserve evaluation of minerals, particularly of uranium, as used worldwide, and specially at NUCLEBRAS is described. This is done through a series of procedures envolving basic definitions, reserve evaluation methods (conventional, statistical and geoestatistical), data management, use of computer systems, classification and evaluation of reserves. (Author) [pt

  9. John Brainerd and the First Indian Reservation.

    Science.gov (United States)

    Harper, Susanne Banta

    1979-01-01

    Describes the humanitarian founding in 1758 of the nation's first reservation--the Brotherton reservation for New Jersey's Lenni Lenape (Algonquin) Indians. The people were demoralized, sick, and decimated in numbers; and so the venture failed. In 1801 those few remaining sold the reservation and moved to join related tribes in New York. (DS)

  10. Flavobacterium johnsoniae chitinase ChiA is required for chitin utilization and is secreted by the type IX secretion system.

    Science.gov (United States)

    Kharade, Sampada S; McBride, Mark J

    2014-03-01

    Flavobacterium johnsoniae, a member of phylum Bacteriodetes, is a gliding bacterium that digests insoluble chitin and many other polysaccharides. A novel protein secretion system, the type IX secretion system (T9SS), is required for gliding motility and for chitin utilization. Five potential chitinases were identified by genome analysis. Fjoh_4555 (ChiA), a 168.9-kDa protein with two glycoside hydrolase family 18 (GH18) domains, was targeted for analysis. Disruption of chiA by insertional mutagenesis resulted in cells that failed to digest chitin, and complementation with wild-type chiA on a plasmid restored chitin utilization. Antiserum raised against recombinant ChiA was used to detect the protein and to characterize its secretion by F. johnsoniae. ChiA was secreted in soluble form by wild-type cells but remained cell associated in strains carrying mutations in any of the T9SS genes, gldK, gldL, gldM, gldNO, sprA, sprE, and sprT. Western blot and liquid chromatography-tandem mass spectrometry (LC-MS/MS) analyses suggested that ChiA was proteolytically processed into two GH18 domain-containing proteins. Proteins secreted by T9SSs typically have conserved carboxy-terminal domains (CTDs) belonging to the TIGRFAM families TIGR04131 and TIGR04183. ChiA does not exhibit strong similarity to these sequences and instead has a novel CTD. Deletion of this CTD resulted in accumulation of ChiA inside cells. Fusion of the ChiA CTD to recombinant mCherry resulted in secretion of mCherry into the medium. The results indicate that ChiA is a soluble extracellular chitinase required for chitin utilization and that it relies on a novel CTD for secretion by the F. johnsoniae T9SS.

  11. Cognitive reserve in ageing and Alzheimer's disease

    Science.gov (United States)

    Stern, Yaakov

    2012-01-01

    The concept of reserve accounts for individual differences in susceptibility to age-related brain changes or Alzheimer's disease-related pathology. There is evidence that some people can tolerate more of these changes than others and still maintain function. Epidemiologic studies suggest that lifetime exposures including educational and occupational attainment, and leisure activities in late life, can increase this reserve. For example, there is a reduced risk of developing Alzheimer's disease in individuals with higher educational or occupational attainment. It is convenient to think of two types of reserve: brain reserve, which refers to actual differences in the brain itself that may increase tolerance of pathology, and cognitive reserve. Cognitive reserve refers to individual differences in how tasks are performed that may allow some people to be more resilient than others. The concept of cognitive reserve holds out the promise of interventions that could slow cognitive aging or reduce the risk of dementia. PMID:23079557

  12. an alternative approach to t reservations for hand ative approach

    African Journals Online (AJOL)

    eobe

    using the Gaussian Elimination method. Key words: Key words: GSM, resource reservation, quality of ser. 1. INTRODUCTION. INTRODUCTION. INTRODUCTION. In a typical cellular network, the radio and fixed l required are not permanently allocated for duration of a call. Handover, which is also referre as handoff in North ...

  13. 15 CFR 30.41-30.44 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false [Reserved] 30.41-30.44 Section 30.41-30.44 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE FOREIGN TRADE REGULATIONS Exemptions From the Requirements for the Filing...

  14. Commercial helium reserves, continental rifting and volcanism

    Science.gov (United States)

    Ballentine, C. J.; Barry, P. H.; Hillegonds, D.; Fontijn, K.; Bluett, J.; Abraham-James, T.; Danabalan, D.; Gluyas, J.; Brennwald, M. S.; Pluess, B.; Seneshens, D.; Sherwood Lollar, B.

    2017-12-01

    Helium has many industrial applications, but notably provides the unique cooling medium for superconducting magnets in medical MRI scanners and high energy beam lines. In 2013 the global supply chainfailed to meet demand causing significant concern - the `Liquid Helium Crisis' [1]. The 2017 closure of Quatar borders, a major helium supplier, is likely to further disrupt helium supply, and accentuates the urgent need to diversify supply. Helium is found in very few natural gas reservoirs that have focused 4He produced by the dispersed decay (a-particle) of U and Th in the crust. We show here, using the example of the Rukwa section of the Tanzanian East African Rift, how continental rifting and local volcanism provides the combination of processes required to generate helium reserves. The ancient continental crust provides the source of 4He. Rifting and associated magmatism provides the tectonic and thermal mechanism to mobilise deep fluid circulation, focusing flow to the near surface along major basement faults. Helium-rich springs in the Tanzanian Great Rift Valley were first identified in the 1950's[2]. The isotopic compositions and major element chemistry of the gases from springs and seeps are consistent with their release from the crystalline basement during rifting [3]. Within the Rukwa Rift Valley, helium seeps occur in the vicinity of trapping structures that have the potential to store significant reserves of helium [3]. Soil gas surveys over 6 prospective trapping structures (1m depth, n=1486) show helium anomalies in 5 out of the 6 at levels similar to those observed over a known helium-rich gas reservoir at 1200m depth (7% He - Harley Dome, Utah). Detailed macroseep gas compositions collected over two days (n=17) at one site allows us to distinguish shallow gas contributions and shows the deep gas to contain between 8-10% helium, significantly increasing resource estimates based on uncorrected values (1.8-4.2%)[2,3]. The remainder of the deep gas is

  15. Demand for International Reserves in Turkey

    Directory of Open Access Journals (Sweden)

    Yimaz Sinem

    2014-06-01

    Full Text Available Having an important place in the international monetary system, international reserves held by central bank usually reflect country’s economic strength in terms of international finance and trade. There are many reasons for holding international reserves by central banks such as financing the deficit in the balance of payment, managing the monetary and exchange rate policies, minimizing the negative effects of external shocks and reducing the cost of borrowing. Continuously changing and diversifying characteristics of these reasons affect the demand for reserves depending to the economic conditions of the country. Over the last ten years, there has been a tremendous increase in international reserves held by Turkish Central Bank. From 2002 to 2012, the reserves of the bank have risen from 20 billion dollars to 96 billion dollars, showing an increase more than four times. This sudden and huge increase in the foreign reserves drove us to determine and investigate the factors which induce the Turkish Central Bank to hold high level of reserves. Thus, the purpose of this study is to estimate and analyze the demand for international reserves held by central banks using the buffer stock model in the case of Turkey. The data used in the study is monthly and cover the period of 1990:03-2012:10. The buffer stock model was econometrically estimated by using the OLS method for three different models. Our findings indicate that the opportunity cost affected reserve demand much stronger than the reserve volatility in Turkish case.

  16. Requirements Engineering

    CERN Document Server

    Hull, Elizabeth; Dick, Jeremy

    2011-01-01

    Written for those who want to develop their knowledge of requirements engineering process, whether practitioners or students.Using the latest research and driven by practical experience from industry, Requirements Engineering gives useful hints to practitioners on how to write and structure requirements. It explains the importance of Systems Engineering and the creation of effective solutions to problems. It describes the underlying representations used in system modeling and introduces the UML2, and considers the relationship between requirements and modeling. Covering a generic multi-layer r

  17. Software requirements

    CERN Document Server

    Wiegers, Karl E

    2003-01-01

    Without formal, verifiable software requirements-and an effective system for managing them-the programs that developers think they've agreed to build often will not be the same products their customers are expecting. In SOFTWARE REQUIREMENTS, Second Edition, requirements engineering authority Karl Wiegers amplifies the best practices presented in his original award-winning text?now a mainstay for anyone participating in the software development process. In this book, you'll discover effective techniques for managing the requirements engineering process all the way through the development cy

  18. Geologic technical assessment of the Chacahoula Salt Dome, Louisiana, for potential expansion of the U.S. strategic petroleum reserve.

    Energy Technology Data Exchange (ETDEWEB)

    Snider, Anna C.; Rautman, Christopher Arthur; Looff, Karl M. (Geologic Consultant, Lovelady, TX)

    2006-03-01

    The Chacahoula salt dome, located in southern Louisiana, approximately 66 miles southwest of New Orleans, appears to be a suitable site for a 160-million-barrel-capacity expansion facility for the U.S. Strategic Petroleum Reserve, comprising sixteen 10-million barrel underground storage caverns. The overall salt dome appears to cover an area of some 1800 acres, or approximately 2.8 square miles, at a subsea elevation of 2000 ft, which is near the top of the salt stock. The shallowest known salt is present at 1116 ft, subsea. The crest of the salt dome is relatively flatlying, outward to an elevation of -4000 ft. Below this elevation, the flanks of the dome plunge steeply in all directions. The dome appears to comprise two separate spine complexes of quasi-independently moving salt. Two mapped areas of salt overhang, located on the eastern and southeastern flanks of the salt stock, are present below -8000 ft. These regions of overhang should present no particular design issues, as the conceptual design SPR caverns are located in the western portion of the dome. The proposed cavern field may be affected by a boundary shear zone, located between the two salt spines. However, the large size of the Chacahoula salt dome suggests that there is significant design flexibility to deal with such local geologic issues.

  19. A General Business Model for Marine Reserves

    Science.gov (United States)

    Sala, Enric; Costello, Christopher; Dougherty, Dawn; Heal, Geoffrey; Kelleher, Kieran; Murray, Jason H.; Rosenberg, Andrew A.; Sumaila, Rashid

    2013-01-01

    Marine reserves are an effective tool for protecting biodiversity locally, with potential economic benefits including enhancement of local fisheries, increased tourism, and maintenance of ecosystem services. However, fishing communities often fear short-term income losses associated with closures, and thus may oppose marine reserves. Here we review empirical data and develop bioeconomic models to show that the value of marine reserves (enhanced adjacent fishing + tourism) may often exceed the pre-reserve value, and that economic benefits can offset the costs in as little as five years. These results suggest the need for a new business model for creating and managing reserves, which could pay for themselves and turn a profit for stakeholder groups. Our model could be expanded to include ecosystem services and other benefits, and it provides a general framework to estimate costs and benefits of reserves and to develop such business models. PMID:23573192

  20. Substantiating the Incurred but not Reported Reserve

    Directory of Open Access Journals (Sweden)

    Georgeta Vintilã

    2009-12-01

    Full Text Available In order to handle past and future liability taken by insurance contracts concluded, any insurance company must constitute and maintain technical reserves. Substantiating technical reserves is done through actuarial methods and its over-evaluation or under-evaluation influence solvency and financial performance of the insurance companies, in the sense of reducing solvency through over-evaluating reserves and, respectively, influencing profit (hence of outstanding tax through under-evaluating reserves. An important reserve for insurance companies is represented by the incurred but not reported reserve, as it allows the estimation of the liability the company may confront in the future, generated by events occurred in the past, which are not currently known in the present but will be reported in the future.

  1. Oak Ridge Reservation annual site environmental report summary for 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-01

    The US Department of Energy (DOE) requires an annual site environmental report from each of the sites operating under its authority. The reports present the results from the various environmental monitoring and surveillance programs carried out during the year. In addition to meeting the DOE requirement, the reports also document compliance with various state and federal laws and regulations. This report was published to fulfill those requirements for the Oak Ridge Reservation (ORR) for calendar year 1995. The report is based on thousands of environmental samples collected on and around the ORR and analyzed during the year. The data on which the report is based are published in Environmental Monitoring and Surveillance on the Oak Ridge Reservation: 1995 Data (ES/ESH-71). Both documents are highly detailed. This summary report is meant for readers who are interested in the monitoring results but who do not need to review the details.

  2. Oak Ridge Reservation annual site environmental report summary for 1995

    International Nuclear Information System (INIS)

    1996-12-01

    The US Department of Energy (DOE) requires an annual site environmental report from each of the sites operating under its authority. The reports present the results from the various environmental monitoring and surveillance programs carried out during the year. In addition to meeting the DOE requirement, the reports also document compliance with various state and federal laws and regulations. This report was published to fulfill those requirements for the Oak Ridge Reservation (ORR) for calendar year 1995. The report is based on thousands of environmental samples collected on and around the ORR and analyzed during the year. The data on which the report is based are published in Environmental Monitoring and Surveillance on the Oak Ridge Reservation: 1995 Data (ES/ESH-71). Both documents are highly detailed. This summary report is meant for readers who are interested in the monitoring results but who do not need to review the details

  3. Impact of ground control on mining reserve estimation

    Energy Technology Data Exchange (ETDEWEB)

    Duncan, G. [AMC Resource Consultants Pty Ltd., Sydney, NSW (Australia)

    2001-07-01

    The estimation of coal resources and reserves is an important and often critical component of the assessment of a mining operation or project. An accurate estimation of reserves in particular is essential for many stages of a mining project - from initial evaluation of the project potential, commitment to a mine development, approval of capital expenditure and/or project finance, through to mine valuation for sale or public listing. Accurate estimation of reserves is also a compulsory reporting requirement for public listed companies as set out in the Australian Stock Exchange (ASX), listing rules. Under these rules, resources and reserves are reported under the JOC Code that incorporates the 'Australian Code for Reporting Identified Coal Resources and Reserves'. These rules are now also used more frequently for non public listed companies. A number of geotechnical parameters play an important role in the process of converting insitu resources to economically recoverable reserves. Whilst these parameters play a role in opencut mining, this paper covers a number of key geotechnical issues that influence the estimation of underground reserves. 11 figs.

  4. IGT calculates world reserves of fossil fuels

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    The Institute of Gas Technology has published the IGT World Reserves Survey, giving their latest tabulation of world reserves of fossil fuels and uranium. The report contains 120 Tables and 41 Figures. Estimates are provided for proved reserves, resources, current production, and life indexes of the non-renewable energy sources of the US and of the world as a whole. World regional data are also provided in many cases. The data are summarized here. 2 figures, 5 tables

  5. Reserve reporting from a banker's perspective

    International Nuclear Information System (INIS)

    Larson, B.O.

    1996-01-01

    A banker's perspective of oil and gas reserve reporting was presented. Topics chosen for discussion emphasized oil and gas lending, and the type of capital which is most relevant to the oil and gas industry. The concept of capital differentiation, potential worst case, and least specialization, were explained. An explanation of the reasons for the lender's different perspective on reserves was given. Methods that banks use to limit risk, and the role that reserve reports play in loan approvals were also reviewed

  6. When will fossil fuel reserves be diminished?

    International Nuclear Information System (INIS)

    Shafiee, Shahriar; Topal, Erkan

    2009-01-01

    Crude oil, coal and gas are the main resources for world energy supply. The size of fossil fuel reserves and the dilemma that 'when non-renewable energy will be diminished' is a fundamental and doubtful question that needs to be answered. This paper presents a new formula for calculating when fossil fuel reserves are likely to be depleted and develops an econometrics model to demonstrate the relationship between fossil fuel reserves and some main variables. The new formula is modified from the Klass model and thus assumes a continuous compound rate and computes fossil fuel reserve depletion times for oil, coal and gas of approximately 35, 107 and 37 years, respectively. This means that coal reserves are available up to 2112, and will be the only fossil fuel remaining after 2042. In the Econometrics model, the main exogenous variables affecting oil, coal and gas reserve trends are their consumption and respective prices between 1980 and 2006. The models for oil and gas reserves unexpectedly show a positive and significant relationship with consumption, while presenting a negative and significant relationship with price. The econometrics model for coal reserves, however, expectedly illustrates a negative and significant relationship with consumption and a positive and significant relationship with price. Consequently, huge reserves of coal and low-level coal prices in comparison to oil and gas make coal one of the main energy substitutions for oil and gas in the future, under the assumption of coal as a clean energy source. (author)

  7. Reservation system with graphical user interface

    KAUST Repository

    Mohamed, Mahmoud A. Abdelhamid

    2012-01-05

    Techniques for providing a reservation system are provided. The techniques include displaying a scalable visualization object, wherein the scalable visualization object comprises an expanded view element of the reservation system depicting information in connection with a selected interval of time and a compressed view element of the reservation system depicting information in connection with one or more additional intervals of time, maintaining a visual context between the expanded view and the compressed view within the visualization object, and enabling a user to switch between the expanded view and the compressed view to facilitate use of the reservation system.

  8. 48 CFR 4.501 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false [Reserved] 4.501 Section 4.501 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL ADMINISTRATIVE MATTERS Electronic Commerce in Contracting 4.501 [Reserved...

  9. 7 CFR 300.1 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false [Reserved] 300.1 Section 300.1 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INCORPORATION BY REFERENCE § 300.1 [Reserved...

  10. 7 CFR 305.4 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false [Reserved] 305.4 Section 305.4 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE PHYTOSANITARY TREATMENTS § 305.4 [Reserved...

  11. 50 CFR 216.42 - Photography. [Reserved

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Photography. [Reserved] 216.42 Section 216.42 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC... MAMMALS Special Exceptions § 216.42 Photography. [Reserved] ...

  12. 9 CFR 73.1a - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false [Reserved] 73.1a Section 73.1a Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS SCABIES IN CATTLE § 73.1a [Reserved] ...

  13. 12 CFR 614.4710 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false [Reserved] 614.4710 Section 614.4710 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM LOAN POLICIES AND OPERATIONS Banks for Cooperatives and Agricultural Credit Banks Financing International Trade § 614.4710 [Reserved] ...

  14. 40 CFR 406.43 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true [Reserved] 406.43 Section 406.43 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS GRAIN MILLS POINT SOURCE CATEGORY Bulgur Wheat Flour Milling Subcategory § 406.43 [Reserved] ...

  15. 40 CFR 406.23 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true [Reserved] 406.23 Section 406.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS GRAIN MILLS POINT SOURCE CATEGORY Corn Dry Milling Subcategory § 406.23 [Reserved] ...

  16. 40 CFR 406.13 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true [Reserved] 406.13 Section 406.13 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS GRAIN MILLS POINT SOURCE CATEGORY Corn Wet Milling Subcategory § 406.13 [Reserved] ...

  17. 24 CFR 891.855 - Replacement reserves.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Replacement reserves. 891.855... § 891.855 Replacement reserves. (a) The mixed-finance owner shall establish and maintain a replacement... the funds will be used to pay for capital replacement costs for the Section 202 or 811 supportive...

  18. 22 CFR 40.69 - [Reserved

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false [Reserved] 40.69 Section 40.69 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH NONIMMIGRANTS AND IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Illegal Entrants and Immigration Violators § 40.69 [Reserved] ...

  19. 21 CFR 211.170 - Reserve samples.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Reserve samples. 211.170 Section 211.170 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL... of deterioration unless visual examination would affect the integrity of the reserve sample. Any...

  20. 8 CFR 325.1 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false [Reserved] 325.1 Section 325.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY NATIONALITY REGULATIONS NATIONALS BUT NOT CITIZENS OF THE UNITED STATES; RESIDENCE WITHIN OUTLYING POSSESSIONS § 325.1 [Reserved] ...

  1. 14 CFR 33.13 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false [Reserved] 33.13 Section 33.13 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; General § 33.13 [Reserved] ...

  2. 14 CFR 35.13 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false [Reserved] 35.13 Section 35.13 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: PROPELLERS Design and Construction § 35.13 [Reserved] ...

  3. 14 CFR 35.11 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false [Reserved] 35.11 Section 35.11 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: PROPELLERS Design and Construction § 35.11 [Reserved] ...

  4. Reserve selection using nonlinear species distribution models.

    Science.gov (United States)

    Moilanen, Atte

    2005-06-01

    Reserve design is concerned with optimal selection of sites for new conservation areas. Spatial reserve design explicitly considers the spatial pattern of the proposed reserve network and the effects of that pattern on reserve cost and/or ability to maintain species there. The vast majority of reserve selection formulations have assumed a linear problem structure, which effectively means that the biological value of a potential reserve site does not depend on the pattern of selected cells. However, spatial population dynamics and autocorrelation cause the biological values of neighboring sites to be interdependent. Habitat degradation may have indirect negative effects on biodiversity in areas neighboring the degraded site as a result of, for example, negative edge effects or lower permeability for animal movement. In this study, I present a formulation and a spatial optimization algorithm for nonlinear reserve selection problems in grid-based landscapes that accounts for interdependent site values. The method is demonstrated using habitat maps and nonlinear habitat models for threatened birds in the Netherlands, and it is shown that near-optimal solutions are found for regions consisting of up to hundreds of thousands grid cells, a landscape size much larger than those commonly attempted even with linear reserve selection formulations.

  5. 7 CFR 1709.202 Policy. - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false [Reserved] 1709.202 Policy. Section 1709.202 Policy... AGRICULTURE ASSISTANCE TO HIGH ENERGY COST COMMUNITIES Bulk Fuel Revolving Fund Grant Program § 1709.202 Policy. [Reserved] ...

  6. 21 CFR 720.5 - [Reserved

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false [Reserved] 720.5 Section 720.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY FILING OF COSMETIC PRODUCT INGREDIENT COMPOSITION STATEMENTS § 720.5 [Reserved] ...

  7. 39 CFR 111.5 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false [Reserved] 111.5 Section 111.5 Postal Service UNITED STATES POSTAL SERVICE POST OFFICE SERVICES [DOMESTIC MAIL] GENERAL INFORMATION ON POSTAL SERVICE § 111.5 [Reserved] ...

  8. 75 FR 44067 - Conservation Reserve Program

    Science.gov (United States)

    2010-07-28

    ... amending the Conservation Reserve Program (CRP) regulations to implement provisions of the Food, Conservation, and Energy Act of 2008 (the 2008 Farm Bill). The 2008 Farm Bill generally extends the existing... Commodity Credit Corporation 7 CFR Part 1410 RIN 0560-AH80 Conservation Reserve Program AGENCY: Commodity...

  9. 7 CFR 1779.79 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false [Reserved] 1779.79 Section 1779.79 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS § 1779.79 [Reserved] ...

  10. 7 CFR 1779.82 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false [Reserved] 1779.82 Section 1779.82 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS § 1779.82 [Reserved] ...

  11. 7 CFR 1779.74 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false [Reserved] 1779.74 Section 1779.74 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS § 1779.74 [Reserved] ...

  12. 7 CFR 1779.26 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false [Reserved] 1779.26 Section 1779.26 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS § 1779.26 [Reserved] ...

  13. 20 CFR 410.394 - [Reserved

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false [Reserved] 410.394 Section 410.394 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Relationship and Dependency § 410.394 [Reserved] ...

  14. 40 CFR 26.1124 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false [Reserved] 26.1124 Section 26.1124 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN SUBJECTS Basic Ethical...-nursing Adults § 26.1124 [Reserved] ...

  15. 26 CFR 1.46-10 - [Reserved

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 1 2010-04-01 2010-04-01 true [Reserved] 1.46-10 Section 1.46-10 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY INCOME TAX INCOME TAXES Rules for Computing Credit for Investment in Certain Depreciable Property § 1.46-10 [Reserved] ...

  16. 34 CFR 97.121 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false [Reserved] 97.121 Section 97.121 Education Office of the Secretary, Department of Education PROTECTION OF HUMAN SUBJECTS Federal Policy for the Protection of Human Subjects (Basic ED Policy for Protection of Human Research Subjects) § 97.121 [Reserved] ...

  17. Running on Empty? The Compensatory Reserve Index

    Science.gov (United States)

    2013-12-01

    and HR,31 more blood pressure oscillations,32 and greater vasoconstrictor reserve,33 compared with low-tolerant individuals. By leveraging recent... vasoconstrictor reserves. Clin Auton Res. 2012; 22:123Y130. 32. Rickards CA, Ryan KL, Cooke WH, Convertino VA. Tolerance to central hypovolemia: the

  18. 77 FR 66980 - Federal Reserve Bank Services

    Science.gov (United States)

    2012-11-08

    ... earn net income of $15.3 million, compared with the target of $9.1 million. While the check service and... upgrades, and increase product revenue. 4. 2013 Pricing--The following summarizes the Reserve Banks... the office closed. The Reserve Banks also will introduce incentive pricing for depository institutions...

  19. 15 CFR 2003.3 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false [Reserved] 2003.3 Section 2003.3 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS OF TRADE POLICY STAFF COMMITTEE § 2003.3 [Reserved] ...

  20. Reserve growth in oil fields of the North Sea

    Science.gov (United States)

    Klett, T.R.; Gautier, D.L.

    2005-01-01

    The assessment of petroleum resources of the North Sea, as well as other areas of the world, requires a viable means to forecast the amount of growth of reserve estimates (reserve growth) for discovered fields and to predict the potential fully developed sizes of undiscovered fields. This study investigates the utility of North Sea oil field data to construct reserve-growth models. Oil fields of the North Sea provide an excellent dataset in which to examine the mechanisms, characteristics, rates and quantities of reserve growth because of the high level of capital investments, implementation of sophisticated technologies and careful data collection. Additionally, these field data are well reported and available publicly. Increases in successive annual estimat es of recoverable crude oil volumes indicate that oil fields in the North Sea, collectively and in each country, experience reserve growth. Specific patterns of reserve growth are observed among countries and primary producing reservoir-rock types. Since 1985, Norwegian oil fields had the greatest volume increase; Danish oil fields increased by the greatest percentage relative to 1985 estimates; and British oil fields experienced an increase in recoverable oil estimates for the first ten years since 1985, followed by a slight reduction. Fields producing primarily from clastic reservoirs account for the majority of the estimated recoverable oil and, therefore, these fields had the largest volumetric increase. Fields producing primarily from chalk (limestone) reservoirs increased by a greater percentage relative to 1985 estimates than did fields producing primarily from clastic reservoirs. Additionally, the largest oil fields had the greatest volumetric increases. Although different reserve-growth patterns are observed among oil fields located in different countries, the small number of fields in Denmark precludes construction of reserve-growth models for that country. However, differences in reserve

  1. 32 CFR 552.56 - Licensing requirements.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Licensing requirements. 552.56 Section 552.56 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY MILITARY RESERVATIONS AND NATIONAL CEMETERIES REGULATIONS AFFECTING MILITARY RESERVATIONS Solicitation on Military Reservations § 552.56 Licensing requirements. To transact...

  2. Czech fiasco with oil reserves has not deterred Slovakia

    International Nuclear Information System (INIS)

    Haluza, I.

    2004-01-01

    In order to meet its obligation to keep a 90-day emergency reserve of oil and oil products, Slovakia must purchase about 40% of the required volume of these commodities and complete storage capacity for the reserves. In addition, it must also create a system of storage management for the reserves including a regular exchange of the contents of the tanks. If it does not meet the 2008 deadline, EU structural funds will be decreased. In order to create the missing storage capacity, the Sprava statnych hmotnych rezerv (SSHR - Administration of Public Material Reserves) is considering a solution which Slovnaft, a.s. sees as a major risk for the state. Should the hundreds of millions needed for the building of new tanks not be found in the budget, the state would invite private investors to build the tanks, stated SSHR Chairman, Jan Tusim. Private investors will not endanger public control over the emergency reserves. Other countries also lease tanks. But according to information provided by its chairman, SSHR also wants to make the private investors responsible for the regular exchange of the emergency reserves that must be carried out every four to five years. Given an accurate forecast of price development on international markets, a lot of money can be made on these exchanges. Slovnaft stresses that if the state were no longer responsible for the exchange of the tanks' contents, it would be the state that was at risk not the refineries

  3. Cognitive reserve and appraisal in multiple sclerosis.

    Science.gov (United States)

    Schwartz, Carolyn E; Snook, Erin; Quaranto, Brian; Benedict, Ralph H B; Rapkin, Bruce D; Vollmer, Timothy

    2013-01-01

    Cognitive appraisal processes underlying self-report affect the interpretation of patient-reported outcomes. These processes are relevant to resilience and adaptability, and may relate to how cognitive reserve protects against disability in multiple sclerosis (MS). To describe how passive and active indicators of cognitive reserve relate to QOL appraisal processes in MS. Cross-sectional data (n=860) were drawn from the North American Research Committee on MS (NARCOMS) Registry, from whom additional survey data were collected. Cognitive reserve was measured using the Stern and Sole-Padulles measures. Using the quality of life appraisal profile (QOLAP), we assessed how MS patients conceptualize their experiences and how that impacts how they report their quality of life. Multivariate analysis of variance was used to compare groups within sets of appraisal parameters, and t-tests or chi-square tests were used to compare mean item responses within appraisal parameters for continuous or dichotomous variables, respectively. People high in passive or active reserve report different conceptualizations of QOL, different types of goals, and considering different types of experiences and standards of comparison in responding to QOL questionnaires, as compared to low-reserve individuals. Although item response patterns were slightly different between passive and active indicators, they generally reflect a tendency in high-reserve individuals to emphasize the positive, focus on aspects of their life that are more controllable, and less based in fantasy. MS patients high in cognitive reserve differ in their cognitive appraisals from their low reserve counterparts. These appraisal metrics may predict disease course and other important clinical outcomes in MS patients. Copyright © 2012 Elsevier B.V. All rights reserved.

  4. Computerized reserves assessment improves colliery planning. [Poland

    Energy Technology Data Exchange (ETDEWEB)

    Pozor, L.; Wrobel, R.

    1984-01-01

    The authors describe systems developed in Poland for the computerised assessment of coal reserves. The Zasoby system calculates coal reserves and evaluates selected natural properties of seams within the boundaries of an arbitrary mining property, based entirely on exploratory borehole data. The IOS-10 system is based on the Polish data bank for bituminous coal deposits. It is not suitable for use in mine design procedures, but is widely used for the statistical recording of reserves in areas currently being worked. The major part of the paper is devoted to a description of the Geo-3 system, used for the computation of reserves in prospective areas from borehole data, as well as in active mining areas or partially worked-out deposits. The computation method is explained and examples of the results obtained are given.

  5. Operational Army Reserve Implications for Organizational Health

    National Research Council Canada - National Science Library

    Dahms, Jonathan A

    2007-01-01

    The Army Reserve has been in a constant state of mobilization since 1995 with the advent of the Bosnia crisis and the pace of mobilization increased exponentially after the terrorist attacks of September 11, 2001...

  6. Communicating marine reserve science to diverse audiences

    Science.gov (United States)

    Grorud-Colvert, Kirsten; Lester, Sarah E.; Airamé, Satie; Neeley, Elizabeth; Gaines, Steven D.

    2010-01-01

    As human impacts cause ecosystem-wide changes in the oceans, the need to protect and restore marine resources has led to increasing calls for and establishment of marine reserves. Scientific information about marine reserves has multiplied over the last decade, providing useful knowledge about this tool for resource users, managers, policy makers, and the general public. This information must be conveyed to nonscientists in a nontechnical, credible, and neutral format, but most scientists are not trained to communicate in this style or to develop effective strategies for sharing their scientific knowledge. Here, we present a case study from California, in which communicating scientific information during the process to establish marine reserves in the Channel Islands and along the California mainland coast expanded into an international communication effort. We discuss how to develop a strategy for communicating marine reserve science to diverse audiences and highlight the influence that effective science communication can have in discussions about marine management. PMID:20427745

  7. 48 CFR 9904.404-10 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... Section 9904.404-10 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.404-10 [Reserved] ...

  8. 48 CFR 9904.401-10 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... Section 9904.401-10 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.401-10 [Reserved] ...

  9. 48 CFR 9904.400 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... Section 9904.400 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.400 [Reserved] ...

  10. 48 CFR 9904.402-10 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... Section 9904.402-10 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.402-10 [Reserved] ...

  11. 48 CFR 9904.405-10 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... Section 9904.405-10 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.405-10 [Reserved] ...

  12. 48 CFR 9904.407-10 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... Section 9904.407-10 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.407-10 [Reserved] ...

  13. 48 CFR 9904.408-10 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... Section 9904.408-10 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.408-10 [Reserved] ...

  14. 48 CFR 9904.406-10 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... Section 9904.406-10 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.406-10 [Reserved] ...

  15. 48 CFR 9904.403-10 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... Section 9904.403-10 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.403-10 [Reserved] ...

  16. 10 CFR 51.110 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR DOMESTIC LICENSING AND RELATED REGULATORY FUNCTIONS National Environmental Policy Act-Regulations Implementing Section 102(2) Rulemaking § 51.110 [Reserved] Public Notice of and Access to Environmental Documents ...

  17. U.S. Federal Reserve Systems

    Data.gov (United States)

    Department of Homeland Security — This dataset is comprised of forty-five entities that are part of the United States Federal Reserve System according to the United States Department of Treasury. The...

  18. Communicating marine reserve science to diverse audiences.

    Science.gov (United States)

    Grorud-Colvert, Kirsten; Lester, Sarah E; Airamé, Satie; Neeley, Elizabeth; Gaines, Steven D

    2010-10-26

    As human impacts cause ecosystem-wide changes in the oceans, the need to protect and restore marine resources has led to increasing calls for and establishment of marine reserves. Scientific information about marine reserves has multiplied over the last decade, providing useful knowledge about this tool for resource users, managers, policy makers, and the general public. This information must be conveyed to nonscientists in a nontechnical, credible, and neutral format, but most scientists are not trained to communicate in this style or to develop effective strategies for sharing their scientific knowledge. Here, we present a case study from California, in which communicating scientific information during the process to establish marine reserves in the Channel Islands and along the California mainland coast expanded into an international communication effort. We discuss how to develop a strategy for communicating marine reserve science to diverse audiences and highlight the influence that effective science communication can have in discussions about marine management.

  19. The Economics of NASA Mission Cost Reserves

    Science.gov (United States)

    Whitley, Sally; Shinn, Stephen

    2012-01-01

    Increases in NASA mission costs have led to analysis of the causes and magnitude of historical mission overruns as well as mitigation and prevention attempts. This paper hypothesizes that one cause is that the availability of reserves may reduce incentives to control costs. We draw a comparison to the insurance concept of moral hazard, and we use actuarial techniques to better understand the increase in mission costs due to the availability of reserves. NASA's CADRe database provided the data against which we tested our hypothesis and discovered that there is correlation between the amount of available reserves and project overruns, particularly for mission hardware cost increases. We address the question of how to prevent reserves from increasing mission spending without increasing cost risk to projects.

  20. 40 CFR 63.131 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES National Emission Standards for Organic Hazardous Air Pollutants From the Synthetic Organic Chemical Manufacturing Industry for Process Vents, Storage Vessels, Transfer Operations, and Wastewater § 63.131 [Reserved] ...

  1. Reserves and cash flows under stochastic retirement

    DEFF Research Database (Denmark)

    Gad, Kamille Sofie Tågholt; Nielsen, Jeppe Woetmann

    2016-01-01

    and the guarantees provided. Stochastic retirement creates a need to rethink the construction of disability products for high ages and ways to handle this are discussed. We show how to calculate market reserves and how to use modified transition probabilities to calculate expected cash flows without significantly...... more complexity than in the traditional model. At last, we demonstrate the impact of stochastic retirement on market reserves and expected cash flow in numerical examples....

  2. Cognitive reserve in ageing and Alzheimer's disease

    OpenAIRE

    Stern, Yaakov

    2012-01-01

    The concept of reserve accounts for individual differences in susceptibility to age-related brain changes or Alzheimer's disease-related pathology. There is evidence that some people can tolerate more of these changes than others and still maintain function. Epidemiologic studies suggest that lifetime exposures including educational and occupational attainment, and leisure activities in late life, can increase this reserve. For example, there is a reduced risk of developing Alzheimer's diseas...

  3. Reserve Component Programs, Fiscal Year 1991

    Science.gov (United States)

    1992-02-28

    utilizing WMrcha’t Marine Academy gr , ,ates and Naval Reserve Officer Training Course S’(NROTC)/Student Incentive Progrim (SIP) graduates from state...personnel gr , atly enhances the mobilization and combat readiness of the Total Force. Several new medical programs were implemented by the Reserve components...Defense Force Chief of Joint Staff, Defense Command * Mendez, Honorable Enrique Jr., M.D. Norway Assistant Secretary of Defense for Health Affairs

  4. Exploration report in mining reserve XIV

    International Nuclear Information System (INIS)

    Spoturno Pioppo, J.; Lara Vigil, P.

    1991-01-01

    This report has been referred to the antecedents and works developed in the mining Reservation XIV. This Reservation, covered a 1900 km2 surface, involving the aerial photography Valentines Cerro Chato, Chileno, Rossel y Rius, Sarandi del Yi and Cuchilla del Pescado. It has been reduced this area to western part of the aerial phothograpy Pavas, releasing other areas such as Chileno, Rossel y Rius, Cuchilla del Pescado y Cerro Chato. Finally, gold, sulphures, pirite and carbonates iron oxides findings have been found.

  5. Unanswered Quibbles with Fractional Reserve Free Banking

    OpenAIRE

    Bagus, Philipp; Howden, David

    2011-01-01

    In this article we reply to George Selgin’s counterarguments to our article “Fractional Reserve Free Banking: Some Quibbles”. Selgin regards holding cash as saving while we focus on the real savings necessary to maintain investment projects. Real savings are unconsumed real income. Variations in real savings are not necessarily equal to variations in cash holdings. We show that a coordinated credit expansion in a fractional reserve free banking (FRFB) system is possible and that precautionary...

  6. Financing options to develop non-conventional reserves

    International Nuclear Information System (INIS)

    Tricoli, C.

    1997-01-01

    The economics of non-conventional natural gas reserves such as coalbed methane, gas shales and tight gas were discussed, with special reference to financing options to develop such reserves. Before 1992, tax credits were used to stimulate the development of non-conventional gas. The requirements for section 29 tax credits, the objectives of investors and producers, and the methods used to monetize section 29 tax credits, such as public royalty trusts, partnership structures, and up-front payment mechanisms were described. The capital gains implications of gas sales were also reviewed. It was noted that in the absence of tax credits, financing the development of non-conventional reserves must undergo the same economic scrutiny as any other oil and gas project

  7. Tiger Team Assessment of the Naval Petroleum Reserves in California

    International Nuclear Information System (INIS)

    1991-12-01

    This report documents the Tiger Team Assessment of the Naval Petroleum Reserves in California (NPRC) which consists of Naval Petroleum Reserve Number 1 (NPR-1), referred to as the Elk Hills oil field and Naval Petroleum Reserve Number 2 (NPR-2), referred to as the Buena Vista oil field, each located near Bakersfield, California. The Tiger Team Assessment was conducted from November 12 to December 13, 1991, under the auspices of DOE's Office of Special Projects (OSP) under the Assistant Secretary for Environment, Safety and Health (EH). The assessment was comprehensive, encompassing environmental, safety, and health (ES ampersand H), and quality assurance (OA) disciplines; site remediation; facilities management; and waste management operations. Compliance with applicable Federal, State of California, and local regulations; applicable DOE Orders; best management practices; and internal NPRC requirements was assessed. In addition, an evaluation of the adequacy and effectiveness of DOE/NPRC, CUSA, and BPOI management of the ES ampersand H/QA programs was conducted

  8. Natural radioactivity as indicator of petroleum reserves

    International Nuclear Information System (INIS)

    Palacios, T.; Viloriab, L.; Sajo Bohusa, K.; Gomez, A.

    2001-01-01

    The possibilities of the measurement method of Radon emanation from the ground, using passive detectors, to identify oil-saturated beds in reserves or well-known deposit was evaluated in the North part of the Orinoco river and in some areas of Zulia Sate, Venezuela. The existence of Negative anomalies of radon emanation in regions of proven petroleum reserves was shown. The Space variability of emanated Radon concentration from the ground was measured and maps of three-dimensional contour curves applying different surface models were obtained, which allowed to locate the anomalies of radon emanation and to compare them with the location of reserves reported by other methods. In both regions it was obtained that the area having the lowest radon value is surrounded by an annular region of high radon values, being able to identify a locally decreased emanation over petroleum reserves as compared to the surroundings. The cause of such anomalies is not identified but they can provide useful information for locating the deeply buried oil reserves. Both regions showed a decrease in gamma activity and in upward flow of gases CH4 and C02 over the geologic structures which contain petroleum reserves Underneath. An applicable experimental routine was proposed to other regions. We conclude that the method of etched track detection can be useful in recognizing the subsurface oil-bearing structures and the technique is relatively simple and inexpensive

  9. Multicell LiSOCl sub 2 reserve battery

    Science.gov (United States)

    Baldwin, A. R.; Garoutte, K. F.

    Recent development work on reverse lithium thionyl chloride (RLTC) batteries at SNLA and Honeywell has included safety and performance evaluations. The RLTC battery is being considered for applications that were traditionally fulfilled by state-of-the-art thermal batteries and reserve silver oxide zinc electrochemical systems. These applications typically demand a reserve battery having a rapid voltage rise, high reliability, operational safety and useful active lifetime ranging from minutes to hours. The RLTC work reported here was directed toward a power battery capable of meeting or exceeding the design requirements. Performance and safety test data indicate that the RLTC battery may be better suited than thermal batteries for some long-life applications. A comparison between Li(Si)/FeS2 thermal battery and an RLTC battery, both of which were designed to fulfill the requirements is presented.

  10. Joint energy and reserve dispatch in a multi-area competitive market ...

    African Journals Online (AJOL)

    ... multi-product, multi-area market dispatch problem with physical and operational constraints. The proposed approach effectively handles the complex constraints like reserve requirements, zonal power balance constraints, area spinning reserve constraints, tie-line constraints and reserve and capacity coupling constraints.

  11. Analysis of a commitment period reserve at national and global levels

    DEFF Research Database (Denmark)

    Missfeldt, F.; Haites, E.

    2002-01-01

    To reduce the risk of overselling in the context of international greenhouse gas trading under the Kyoto Protocol, Parties have agreed to a commitment period reserve requirement. The commitment period reserve requires each Annex B Party to hold in its national registry quota equal to the lower of...

  12. Resting site use of giant pandas in Wanglang Nature Reserve

    OpenAIRE

    Kang, Dongwei; Wang, Xiaorong; Li, Junqing

    2017-01-01

    Little is known about the resting sites used by the giant panda (Ailuropoda melanoleuca), which restricts our understanding of their resting habits and limits conservation efforts. To enhance our understanding of resting site requirements and factors affecting the resting time of giant pandas, we investigated the characteristics of resting sites in the Wanglang Nature Reserve, Sichuan Province, China. The results indicated that the resting sites of giant pandas were characterised by a mean sl...

  13. Closure requirements

    International Nuclear Information System (INIS)

    Hutchinson, I.P.G.; Ellison, R.D.

    1992-01-01

    Closure of a waste management unit can be either permanent or temporary. Permanent closure may be due to: economic factors which make it uneconomical to mine the remaining minerals; depletion of mineral resources; physical site constraints that preclude further mining and beneficiation; environmental, regulatory or other requirements that make it uneconomical to continue to develop the resources. Temporary closure can occur for a period of several months to several years, and may be caused by factors such as: periods of high rainfall or snowfall which prevent mining and waste disposal; economic circumstances which temporarily make it uneconomical to mine the target mineral; labor problems requiring a cessation of operations for a period of time; construction activities that are required to upgrade project components such as the process facilities and waste management units; and mine or process plant failures that require extensive repairs. Permanent closure of a mine waste management unit involves the provision of durable surface containment features to protect the waters of the State in the long-term. Temporary closure may involve activities that range from ongoing maintenance of the existing facilities to the installation of several permanent closure features in order to reduce ongoing maintenance. This paper deals with the permanent closure features

  14. CONCEPT OF FORMATION OF RESERVES AS AN OBJECT OF ACCOUNTING

    Directory of Open Access Journals (Sweden)

    Dubinina M.

    2018-01-01

    reflect, as part of the expense of the current period, the amount that may be required to cover future losses. The modern methodology for accounting for reserves in agricultural enterprises in Ukraine involves the classification of reserves: internal and external reserves.

  15. Oak Ridge reservation, annual site environmental report summary for 1993

    International Nuclear Information System (INIS)

    1994-11-01

    The U.S. Department of Energy requires annual site environmental reports from facilities that operate under its auspices. To fulfill that requirement, such an annual report is published for the Oak Ridge Reservation, which comprises three major sites, each of which has unique monitoring requirements in addition to many shared obligations. As a result, the report is complex and highly detailed. Annual site environmental reports are public documents that are read by government regulators, scientists, engineers, business people, special interest groups, and members of the public at large. For that reason, the reports need to be accessible to a variety of audiences in addition to being accurate and complete. This pamphlet summarizes environmental activities on the reservation, which for some readers may be adequate; for those who seek more detail, it will lend coherence to their approach to the report itself. The content of this summary was taken from Oak Ridge Reservation Annual Site Environmental Report for 1993. Results of the many environmental monitoring and surveillance activities are detailed in this report

  16. Does cognitive reserve shape cognitive decline?

    Science.gov (United States)

    Marmot, Michael G; Glymour, Maria; Sabia, Séverine; Kivimäki, Mika; Dugravot, Aline

    2011-01-01

    Objectives Cognitive reserve is associated with a lower risk of dementia but the extent to which it shapes cognitive aging trajectories remains unclear. Our objective is to examine the impact of three markers of reserve from different points in the lifecourse on cognitive function and decline in late adulthood. Methods Data are from 5234 men and 2220 women, mean age 56 years (standard deviation=6) at baseline, from the Whitehall II cohort study. Memory, reasoning, vocabulary, phonemic and semantic fluency were assessed three times over 10 years. Linear mixed models were used to assess the association between markers of reserve (height, education, and occupation) and cognitive decline, using the 5 cognitive tests and a global cognitive score composed of these tests. Results All three reserve measures were associated with baseline cognitive function, with strongest associations with occupation and the weakest with height. All cognitive functions except vocabulary declined over the 10 year follow-up period. On the global cognitive test, there was greater decline in the high occupation group (−0.27; 95% confidence interval (CI): −0.28, −0.26) compared to the intermediate (−0.23; 95% CI: −0.25, −0.22) and low groups (−0.21; 95% CI: −0.24, −0.19); p=0.001. The decline in reserve groups defined by education (p=0.82) and height (p=0.55) was similar. Interpretation Cognitive performance over the adult lifecourse was remarkably higher in the high reserve groups. However, rate of cognitive decline did not differ between reserve groups except occupation where there was some evidence of greater decline in the high occupation group. PMID:21563209

  17. OPINIONS ON INTERNATIONAL RESERVES MANAGEMENT - POST CRISIS

    Directory of Open Access Journals (Sweden)

    MERCEA (HANDRO PATRICIA AMALIA

    2017-11-01

    Full Text Available The recent crisis demonstrated once again the importance of maintaining an adequate level of the international reserves as part of the defense of a country against the shocks internationally transmitted. Liquidity buffers aided the good functioning of financial systems, and allowed countries to cope with sudden foreign capital stops or to manage massive outflows without facing a costly crisis. This logic has been strengthened in the context of the crisis from 2008, when countries with lots of reserves, such as China or Brazil, came through better than those with lower liquid assets. Economists have argued that developing countries need reserves mainly to cover urgent imports and short-term debts. The current level of global reserves far exceeds this traditional postulate. In this context, it is necessary to rethink the adequacy of the level of constituting the reserves portfolio. The dominance of the dollar as a reserve currency, another important feature of the current reserves portfolio, makes the holders become vulnerable to the monetary policy of FED. A greater flexibility of the currency will also be needed. The often called the “trilemma” of international economics dictates: when capital is mobile, countries must choose between fixing their currencies and controlling their domestic monetary conditions. They cannot do both. The domestic currency inflexibility will ultimately lead to asset bubbles and inflation. The pressure of capital flows will depend on the prospects of rich economies, especially America’s. The increment of emerging economies availability to allow the exchange rate to move will depend on what China does - and China may remain forever linked to the dollar. The emergence of a global currency that constitute a genuine means of exchange or the use of cross-border multifaceted cash pools common to IMF members would reduce systemic risks. International regulations for countries with persistent trade surpluses could be a

  18. Etnologická reflexia zmien v rolovom správaní mužov otcov po rozvode manželstva

    Directory of Open Access Journals (Sweden)

    Daniela Rajniaková

    2015-06-01

    Full Text Available Fatherhood is not some fixed role thatexists forever. Every generation and every cultureinterprets and defines the fatherly role differently.This is due to the fact that the father is closelyrelated to the individual concepts of masculinity,and therefore any discussion of paternity hasa past and a future. Family breakdown and shiftinggender roles, on the part of women as well asmen. These changes are becoming more commonand are therefore receiving increasing attention inthe research discourse. Post subject, the analysisof changes occurring in the role behavior of menafter the divorce of a married couple, changes inmasculinity. Any analysis of paternity, however,requires some awareness of the specific cultural,economic and social conditions that lead to establishedstandards for the proper behavior offathers.Keywords—bringin

  19. Strategic Petroleum Reserve annual report for calendar year 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    The Strategic Petroleum Reserve was established in 1975 as an emergency response to the 1973 Arab oil embargo. It is authorized by the Energy Policy and Conservation Act (EPCA), and by the comprehensive energy plans of all Administrations since 1975, in recognition of the long-term dependence of the US on imported crude oil and petroleum products. Section 165 of EPCA requires the Secretary of Energy to submit an Annual Report to the President and the Congress. On May 13, 1998, the Department published a Statement of Administration Policy which reaffirmed its commitment to maintain a Government-owned and controlled, centrally located Strategic Petroleum Reserve of crude oil. The Reserve is to be used solely for responding to the types of severe oil supply interruptions presently contemplated in EPCA. Over the past twenty years, the Reserve has grown as large as 592 million barrels--a peak reached in 1994. From 1994 to 1996, nearly 28 million barrels were sold to raise revenues for the U S Treasury. As of December 31, 1998, the crude oil inventory was 561,108,127 barrels which equated to 60 days of net oil imports during 1998. The US now relies on a combination of both the Reserve and private stocks to meet its oil storage obligations to the International Energy Agency.

  20. Moisture movement in soils on the Hanford Reservation

    International Nuclear Information System (INIS)

    Brownell, L.E.; Isaacson, R.E.; Sloughter, J.P.; Veatch, M.D.

    1971-01-01

    Methods being studied are as follows: the thermodynamic method based on water potential and thermocouple psychrometers; the tracer method using atmospheric tritium; the annual water balance based on the annual heat balance; the field lysimeter using thermocouple psychrometers; the influence of soil breathing as a result of changes in barometric pressure; and the influence of soil stratification. Progress to date has involved the installation of thermocouple psychrometers from the surface to the water table 310 feet below. These instruments are in the process of equilibration. Isothermal methods of analyzing water potential must be extended to include nonisothermal conditions which are dominant at the Hanford Reservation. Tracer techniques using tritium analyses of soil samples have successfully demonstrated that archaic water exists in virgin soil at the Hanford Reservation from a depth of approximately 7 meters to the water table, indicating that percolation has been limited to lesser depths. The annual heat balance indicates that quantities of water many times greater than the annual average precipitation of 16 centimeters can be evaporated from the soils at the Hanford Reservation during a normal summer. This indicates that the critical precipitation (P/sub c/) value may be greater than 30 to 50 centimeters of water. More precise values of the Bowen's ratio for the Hanford Reservation are required to refine this computation. The field lysimeter is perhaps the most direct method of determining the critical precipitation values for the Hanford Reservation but as yet has not been used

  1. Foreign Exchange Reserves and the Reserve Bank’s Balance Sheet

    OpenAIRE

    Christian Vallence

    2012-01-01

    The Reserve Bank of Australia holds and manages the nation’s foreign exchange reserve assets in order to meet its policy objectives. While Australia’s foreign exchange reserves are relatively modest by international standards, they nonetheless constitute a sizeable portion of the Bank’s balance sheet, and variations in the Australian dollar value of these reserves are usually the most volatile component of the Bank’s profit and loss statement. This article discusses some of the key decisions ...

  2. Xanthine oxidase functionalized Ta2O5nanostructures as a novel scaffold for highly sensitive SPR based fiber optic xanthine sensor.

    Science.gov (United States)

    Kant, Ravi; Tabassum, Rana; Gupta, Banshi D

    2018-01-15

    Fabrication and characterization of a surface plasmon resonance based fiber optic xanthine sensor using entrapment of xanthine oxidase (XO) enzyme in several nanostructures of tantalum (v) oxide (Ta 2 O 5 ) have been reported. Chemical route was adopted for synthesizing Ta 2 O 5 nanoparticles, nanorods, nanotubes and nanowires while Ta 2 O 5 nanofibers were prepared by electrospinning technique. The synthesized Ta 2 O 5 nanostructures were characterized by photoluminescence, scanning electron microscopy, UV-Visible spectra and X-ray diffraction pattern. The probes were fabricated by coating an unclad core of the fiber with silver layer followed by the deposition of XO entrapped Ta 2 O 5 nanostructures. The crux of sensing mechanism relies on the modification of dielectric function of sensing layer upon exposure to xanthine solution of diverse concentrations, reflected in terms of shift in resonance wavelength. The sensing probe coated with XO entrapped Ta 2 O 5 nanofibers has been turned out to possess maximum sensitivity amongst the synthesized nanostructures. The probe was optimized in terms of pH of the sample and the concentration of XO entrapped in Ta 2 O 5 nanofibers. The optimized sensing probe possesses a remarkably good sensitivity of 26.2nm/µM in addition to linear range from 0 to 3µM with an invincible LOD value of 0.0127µM together with a response time of 1min. Furthermore, probe selectivity with real sample analysis ensure the usage of the sensor for practical scenario. The results reported open a novel perspective towards a sensitive, rapid, reliable and selective detection of xanthine. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Wind offering in energy and reserve markets

    DEFF Research Database (Denmark)

    Soares, Tiago; Pinson, Pierre; Morais, Hugo

    2016-01-01

    The increasing penetration of wind generation in power systems to fulfil the ambitious European targets will make wind power producers to play an even more important role in the future power system. Wind power producers are being incentivized to participate in reserve markets to increase their re......The increasing penetration of wind generation in power systems to fulfil the ambitious European targets will make wind power producers to play an even more important role in the future power system. Wind power producers are being incentivized to participate in reserve markets to increase...... dayahead and balancing market is performed. A set of numerical examples illustrate the behavior of such strategy. An important conclusion is that the optimal split of the available wind power between energy and reserve strongly depends upon prices and penalties on both market trading floors....

  4. Right hemisphere role in cognitive reserve.

    Science.gov (United States)

    Robertson, Ian H

    2014-06-01

    High levels of education, occupational complexity, and/or premorbid intelligence are associated with lower levels of cognitive impairment than would be expected from a given brain pathology. This has been observed across a range of conditions including Alzheimer's disease (Roe et al., 2010), stroke (Ojala-Oksala et al., 2012), traumatic brain injury (Kesler et al., 2003), and penetrating brain injury (Grafman, 1986). This cluster of factors, which seemingly protect the brain from expressing symptoms of damage, has been termed "cognitive reserve" (Stern, 2012). The current review considers one possible neural network, which may contribute to cognitive reserve. Based on the evidence that the neurotransmitter, noradrenaline mediates cognitive reserve's protective effects (Robertson, 2013) this review identifies the neurocognitive correlates of noradrenergic (NA) activity. These involve a set of inter-related cognitive processes (arousal, sustained attention, response to novelty, and awareness) with a strongly right hemisphere, fronto-parietal localization, along with working memory, which is also strongly modulated by NA. It is proposed that this set of processes is one plausible candidate for partially mediating the protective effects of cognitive reserve. In addition to its biological effects on brain structure and function, NA function may also facilitate networks for arousal, novelty, attention, awareness, and working memory, which collectively provide for a set of additional, cognitive, mechanisms that help the brain adapt to age-related changes and disease. It is hypothesized that to the extent that the lateral surface of the right prefrontal lobe and/or the right inferior parietal lobe maintain structural (white and gray matter) and functional integrity and connectivity, cognitive reserve should benefit and behavioral expression of pathologic damage should thus be mitigated. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. Risk spreading, connectivity, and optimal reserve spacing.

    Science.gov (United States)

    Blowes, Shane A; Connolly, Sean R

    2012-01-01

    Two important processes determining the dynamics of spatially structured populations are dispersal and the spatial covariance of demographic fluctuations. Spatially explicit approaches to conservation, such as reserve networks, must consider the tension between these two processes and reach a balance between distances near enough to maintain connectivity, but far enough to benefit from risk spreading. Here, we model this trade-off. We show how two measures of metapopulation persistence depend on the shape of the dispersal kernel and the shape of the distance decay in demographic covariance, and we consider the implications of this trade-off for reserve spacing. The relative rates of distance decay in dispersal and demographic covariance determine whether the long-run metapopulation growth rate, and quasi-extinction risk, peak for adjacent patches or intermediately spaced patches; two local maxima in metapopulation persistence are also possible. When dispersal itself fluctuates over time, the trade-off changes. Temporal variation in mean distance that propagules are dispersed (i.e., propagule advection) decreases metapopulation persistence and decreases the likelihood that persistence will peak for adjacent patches. Conversely, variation in diffusion (the extent of random spread around mean dispersal) increases metapopulation persistence overall and causes it to peak at shorter inter-patch distances. Thus, failure to consider temporal variation in dispersal processes increases the risk that reserve spacings will fail to meet the objective of ensuring metapopulation persistence. This study identifies two phenomena that receive relatively little attention in empirical work on reserve spacing, but that can qualitatively change the effectiveness of reserve spacing strategies: (1) the functional form of the distance decay in covariance among patch-specific demographic rates and (2) temporal variation in the shape of the dispersal kernel. The sensitivity of metapopulation

  6. Estimating Quartz Reserves Using Compositional Kriging

    Directory of Open Access Journals (Sweden)

    J. Taboada

    2013-01-01

    Full Text Available The aim of this study was to determine spatial distribution and volume of four commercial quartz grades, namely, silicon metal, ferrosilicon, aggregate, and kaolin (depending on content in impurities in a quartz seam. The chemical and mineralogical composition of the reserves in the seam were determined from samples collected from outcrops, blasting operations, and exploratory drilling, and compositional kriging was used to calculate the volume and distribution of the reserves. A more accurate knowledge of the deposit ensures better mine planning, leading to higher profitability and an improved relationship with the environment.

  7. Political economy of marine reserves: Understanding the role of opportunity costs

    Science.gov (United States)

    Smith, Martin D.; Lynham, John; Sanchirico, James N.; Wilson, James A.

    2010-01-01

    The creation of marine reserves is often controversial. For decisionmakers, trying to find compromises, an understanding of the timing, magnitude, and incidence of the costs of a reserve is critical. Understanding the costs, in turn, requires consideration of not just the direct financial costs but also the opportunity costs associated with reserves. We use a discrete choice model of commercial fishermen’s behavior to examine both the short-run and long-run opportunity costs of marine reserves. Our results can help policymakers recognize the factors influencing commercial fishermen’s responses to reserve proposals. More generally, we highlight the potential drivers behind the political economy of marine reserves. PMID:20133732

  8. Demand as Frequency-controlled Reserve

    DEFF Research Database (Denmark)

    Bang, Christian; Rasmussen, Christian Brandt; Østergaard, Jacob

    electric loads to provide frequency controlled primary reserves. The devices collected data from domestic households and industrial loads covering i.e. circulation pumps, electrical domestic heating, bottle coolers, a wastewater treatment plant etc., that have been analysed and used for the papers...

  9. 34 CFR 300.811 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false [Reserved] 300.811 Section 300.811 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION OF CHILDREN WITH...

  10. 34 CFR 300.805 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false [Reserved] 300.805 Section 300.805 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION OF CHILDREN WITH...

  11. Use of reserve substances by irradiated tubers

    International Nuclear Information System (INIS)

    Perez Tabares, Francisco; Perez Talavera, Susana

    1999-01-01

    The response of tubers of potato (Solanum tuberosun L.) and sweet potato (Ipomoea batatas L.) to gamma radiation from 60 Co were investigated. The use of reserve substances by the tubers increased when the irradiation dose raise up to the level of GR10-20 and then decreased down to the values lower than the control non-irradiated tubers

  12. Diminished ovarian reserve in patients with psoriasis

    Directory of Open Access Journals (Sweden)

    Burcu Tuğrul Ayanoğlu

    2018-04-01

    Full Text Available Objective: Psoriasis is a multi-systemic chronic inflammatory skin disease. Previous data suggests that women with some chronic inflammatory diseases have diminished ovarian reserve. This study explores ovarian reserve in patients with psoriasis. Materials and methods: We prospectively analyzed 14 female patients with psoriasis and 35 healthy age and body mass index matched controls. An interview explored demographic characteristics, obstetrical history and menstrual characteristics. Psoriatic area severity index (PASI in patients was assessed. Estrogen, follicle-stimulating hormone (FSH, luteinizing hormone (LH, thyroid stimulating hormone and with gynecologic ultrasonography, ovarian volume and antral follicular count (AFC were measured in both study and control groups. These values were analyzed with changes of the PASI in the patient group. Results: Patients with psoriasis had significantly higher levels of FSH and FSH/LH ratio than healthy controls (p = 0.039, p = 0.005 respectively. AFC of psoriasis patients were significantly lower than healthy controls (p = 0.002.There were no significant difference among other hormone levels and ovarian volumes (p > 0.05. The hormone levels, ovarian volume and AFC were not correlated with PASI of the patients. Conclusion: The results of the study suggest that patients with psoriasis may have diminished ovarian reserve. Keywords: Psoriasis, Ovarian reserve, Psoriatic area severity index, Antral follicular count, Follicle-stimulating hormone

  13. 49 CFR 236.533 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false [Reserved] 236.533 Section 236.533 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RULES, STANDARDS, AND INSTRUCTIONS GOVERNING THE INSTALLATION, INSPECTION, MAINTENANCE, AND REPAIR...

  14. 49 CFR 236.704 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false [Reserved] 236.704 Section 236.704 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RULES, STANDARDS, AND INSTRUCTIONS GOVERNING THE INSTALLATION, INSPECTION, MAINTENANCE, AND REPAIR...

  15. 49 CFR 236.561 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false [Reserved] 236.561 Section 236.561 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RULES, STANDARDS, AND INSTRUCTIONS GOVERNING THE INSTALLATION, INSPECTION, MAINTENANCE, AND REPAIR...

  16. 49 CFR 236.530 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false [Reserved] 236.530 Section 236.530 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RULES, STANDARDS, AND INSTRUCTIONS GOVERNING THE INSTALLATION, INSPECTION, MAINTENANCE, AND REPAIR...

  17. Oak Ridge Reservation Waste Management Plan

    Energy Technology Data Exchange (ETDEWEB)

    Turner, J.W. [ed.

    1995-02-01

    This report presents the waste management plan for the Oak Ridge Reservation facilities. The primary purpose is to convey what facilities are being used to manage wastes, what forces are acting to change current waste management systems, and what plans are in store for the coming fiscal year.

  18. Optimization of Marine Forces Reserve Equipment Redistribution

    Science.gov (United States)

    2016-06-01

    industry as an example. Bertrand and Bookbinder begin with a basic supply chain logistics model of a large warehouse supplying a number of retail...solutions, and perform fast sensitivity analysis on the competing objectives. 14. SUBJECT TERMS Optimization, Marine Forces Reserve, redistribution...reallocation, equipment supply , logistics 15. NUMBER OF PAGES 61 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT Unclassified 18. SECURITY

  19. Wind offering in energy and reserve markets

    Science.gov (United States)

    Soares, T.; Pinson, P.; Morais, H.

    2016-09-01

    The increasing penetration of wind generation in power systems to fulfil the ambitious European targets will make wind power producers to play an even more important role in the future power system. Wind power producers are being incentivized to participate in reserve markets to increase their revenue, since currently wind turbine/farm technologies allow them to provide ancillary services. Thus, wind power producers are to develop offering strategies for participation in both energy and reserve markets, accounting for market rules, while ensuring optimal revenue. We consider a proportional offering strategy to optimally decide upon participation in both markets by maximizing expected revenue from day-ahead decisions while accounting for estimated regulation costs for failing to provide the services. An evaluation of considering the same proportional splitting of energy and reserve in both day- ahead and balancing market is performed. A set of numerical examples illustrate the behavior of such strategy. An important conclusion is that the optimal split of the available wind power between energy and reserve strongly depends upon prices and penalties on both market trading floors.

  20. Clipboard: Unraveling the mystery of cognitive reserve

    Indian Academy of Sciences (India)

    Aging; Alzheimer's; bilingualism; cognitive reserve; dementia; Down's; education; enrichment; environment; learning; long term potentiation; LTP; memory; neuroepigenetics; plasticity ... Institute of Cognitive Neuroscience, University College London Alexandra House, 17-19 Queen Square, London WC1N 3AR, England ...

  1. Oak Ridge Reservation Waste Management Plan

    International Nuclear Information System (INIS)

    Turner, J.W.

    1995-02-01

    This report presents the waste management plan for the Oak Ridge Reservation facilities. The primary purpose is to convey what facilities are being used to manage wastes, what forces are acting to change current waste management systems, and what plans are in store for the coming fiscal year

  2. 40 CFR 80.605 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false [Reserved] 80.605 Section 80.605 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Motor Vehicle Diesel Fuel; Nonroad, Locomotive, and Marine Diesel Fuel; and ECA...

  3. 40 CFR 80.609 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false [Reserved] 80.609 Section 80.609 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Motor Vehicle Diesel Fuel; Nonroad, Locomotive, and Marine Diesel Fuel; and ECA...

  4. 40 CFR 80.534 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false [Reserved] 80.534 Section 80.534 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Motor Vehicle Diesel Fuel; Nonroad, Locomotive, and Marine Diesel Fuel; and ECA...

  5. Study on Online Hotel Reservation Systems

    OpenAIRE

    Alleweldt, Frank; Tonner, Klaus; McDonald, Marc

    2009-01-01

    This study, conducted by Civic Consulting, looks at both pre-contractual and contractual matters concerning online hotel reservation systems, examines relevant Community rules, identifies gaps and, where needed, discusses possible policy options. Key conclusions The study shows that the impact of Community law on online hotel

  6. 10 CFR 51.99 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false [Reserved] 51.99 Section 51.99 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR DOMESTIC LICENSING AND RELATED REGULATORY FUNCTIONS National Environmental Policy Act-Regulations Implementing Section 102(2) Final Environmental...

  7. Your Money and the Federal Reserve System.

    Science.gov (United States)

    Federal Reserve Bank of Minneapolis, Minn.

    The booklet explores various roles which money has played throughout history and examines the relationship between money and the Federal Reserve System. The major objective is to increase understanding of the performance of various functions such as making money work as a medium of exchange and as a measure of value and of storing value for future…

  8. Mental Reservation and Military Testimony before Congress

    National Research Council Canada - National Science Library

    Roberts, Gordon R

    2008-01-01

    .... The cause for this apparent mental reservation on the part of military leaders can be found in their organizational bias and environmental influences, but the solution can be found in history. It is vital for the military to understand that a currency of truth is the most important contribution it can make to the civilian-military relationship.

  9. 18 CFR 4.91 - [Reserved

    Science.gov (United States)

    2010-04-01

    ... 4.91 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT LICENSES, PERMITS, EXEMPTIONS, AND DETERMINATION OF PROJECT COSTS Exemption of Small Conduit Hydroelectric Facilities § 4.91 [Reserved] ...

  10. Unanswered Quibbles with Fractional Reserve Free Banking

    Directory of Open Access Journals (Sweden)

    Philipp Bagus

    2011-07-01

    Full Text Available In this article we reply to George Selgin’s counterarguments to our article “Fractional Reserve Free Banking: Some Quibbles”. Selgin regards holding cash as saving while we focus on the real savings necessary to maintain investment projects. Real savings are unconsumed real income. Variations in real savings are not necessarily equal to variations in cash holdings. We show that a coordinated credit expansion in a fractional reserve free banking (FRFB system is possible and that precautionary reserves consequently do not pose a necessary limit. We discuss various instances in which a FRFB system may expand credit without a prior increase in real savings. These facets all demonstrate why a fractional reserve banking system – even a free banking one – is inherently unstable, and incentivized to impose a stabilizing central bank. We find that at the root of our disagreements with Selgin lies a different approach to monetary theory. Selgin subscribes to the aggregative equation of exchange, which impedes him from seeing the microeconomic problems that the stabilization of “MV” by a FRFB system causes.

  11. 78 FR 66715 - Federal Reserve Bank Services

    Science.gov (United States)

    2013-11-06

    ... imputed costs and earn net income of $24.6 million, compared with the target of $4.2 million. Although the... initiatives, and to increase product revenue. 4.2014 Pricing--The following summarizes the Reserve Banks... Banks will discontinue the Choice Receiver program, which provides pricing incentives to those customers...

  12. 40 CFR 427.84 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false [Reserved] 427.84 Section 427.84 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ASBESTOS MANUFACTURING POINT SOURCE CATEGORY Coating or Finishing of Asbestos Textiles Subcategory § 427.84...

  13. 40 CFR 86.220-94 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false [Reserved] 86.220-94 Section 86.220-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... Year Gasoline-Fueled New Light-Duty Vehicles, New Light-Duty Trucks and New Medium-Duty Passenger...

  14. 40 CFR 86.217-94 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false [Reserved] 86.217-94 Section 86.217-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... Year Gasoline-Fueled New Light-Duty Vehicles, New Light-Duty Trucks and New Medium-Duty Passenger...

  15. 40 CFR 86.212-94 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false [Reserved] 86.212-94 Section 86.212-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... Year Gasoline-Fueled New Light-Duty Vehicles, New Light-Duty Trucks and New Medium-Duty Passenger...

  16. 40 CFR 86.241-94 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false [Reserved] 86.241-94 Section 86.241-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... Year Gasoline-Fueled New Light-Duty Vehicles, New Light-Duty Trucks and New Medium-Duty Passenger...

  17. 40 CFR 86.207-94 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false [Reserved] 86.207-94 Section 86.207-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... Year Gasoline-Fueled New Light-Duty Vehicles, New Light-Duty Trucks and New Medium-Duty Passenger...

  18. 40 CFR 86.243-94 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false [Reserved] 86.243-94 Section 86.243-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... Year Gasoline-Fueled New Light-Duty Vehicles, New Light-Duty Trucks and New Medium-Duty Passenger...

  19. 40 CFR 428.64 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false [Reserved] 428.64 Section 428.64 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS RUBBER MANUFACTURING POINT SOURCE CATEGORY Medium-Sized General Molded, Extruded, and Fabricated Rubber...

  20. 40 CFR 86.210-94 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false [Reserved] 86.210-94 Section 86.210-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... Year Gasoline-Fueled New Light-Duty Vehicles, New Light-Duty Trucks and New Medium-Duty Passenger...

  1. 40 CFR 86.245-94 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false [Reserved] 86.245-94 Section 86.245-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... Year Gasoline-Fueled New Light-Duty Vehicles, New Light-Duty Trucks and New Medium-Duty Passenger...

  2. 40 CFR 86.225-94 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false [Reserved] 86.225-94 Section 86.225-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... Year Gasoline-Fueled New Light-Duty Vehicles, New Light-Duty Trucks and New Medium-Duty Passenger...

  3. 5 CFR 330.710 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false [Reserved] 330.710 Section 330.710 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS RECRUITMENT, SELECTION, AND PLACEMENT (GENERAL) Interagency Career Transition Assistance Plan for Displaced Employees § 330.710...

  4. 5 CFR 330.702 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false [Reserved] 330.702 Section 330.702 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS RECRUITMENT, SELECTION, AND PLACEMENT (GENERAL) Interagency Career Transition Assistance Plan for Displaced Employees § 330.702...

  5. Membrane Association of the PTEN Tumor Suppressor: Molecular Details of the Protein-Membrane Complex from SPR Binding Studies and Neutron Reflection

    Science.gov (United States)

    Shenoy, Siddharth; Shekhar, Prabhanshu; Heinrich, Frank; Daou, Marie-Claire; Gericke, Arne; Ross, Alonzo H.; Lösche, Mathias

    2012-01-01

    The structure and function of the PTEN phosphatase is investigated by studying its membrane affinity and localization on in-plane fluid, thermally disordered synthetic membrane models. The membrane association of the protein depends strongly on membrane composition, where phosphatidylserine (PS) and phosphatidylinositol diphosphate (PI(4,5)P2) act pronouncedly synergistic in pulling the enzyme to the membrane surface. The equilibrium dissociation constants for the binding of wild type (wt) PTEN to PS and PI(4,5)P2 were determined to be Kd∼12 µM and 0.4 µM, respectively, and Kd∼50 nM if both lipids are present. Membrane affinities depend critically on membrane fluidity, which suggests multiple binding sites on the protein for PI(4,5)P2. The PTEN mutations C124S and H93R show binding affinities that deviate strongly from those measured for the wt protein. Both mutants bind PS more strongly than wt PTEN. While C124S PTEN has at least the same affinity to PI(4,5)P2 and an increased apparent affinity to PI(3,4,5)P3, due to its lack of catalytic activity, H93R PTEN shows a decreased affinity to PI(4,5)P2 and no synergy in its binding with PS and PI(4,5)P2. Neutron reflection measurements show that the PTEN phosphatase “scoots" along the membrane surface (penetration protein, ∼60 Å away from the bilayer surface, in a rather compact structure. The combination of binding studies and neutron reflection allows us to distinguish between PTEN mutant proteins and ultimately may identify the structural features required for membrane binding and activation of PTEN. PMID:22505997

  6. Planning outstanding reserves in general insurance

    Science.gov (United States)

    Raeva, E.; Pavlov, V.

    2017-10-01

    Each insurance company have to ensure its solvency through presentation of accounts for its own reserves in the start of the year. Usually the task of the actuary is to estimate the state of the company on an annual basis and the expectation of the status of the company for a future period. One of the major problem when calculating the liabilities of the incurred claims, is related to the delay of payments. Object of consideration in the present note are the outstanding claim reserves, which are set aside to cover claims, occurred before the date of the annual account, but still not paid, and related with them expenses. There may be different reasons for the delay of claims settlement. For example, continuation the process of the liquidation of the damage waiting for necessary documents or the presence of controversial cases whose permission takes time, etc. Thus the claims, which determine the outstanding reserves could be divided in the following types: claims, which are reported, but not settled (RBNS); claims, which are incurred but not reported (IBNR); claims, whose case is finished, but it is possible to be reopened. When calculating the reserves for IBNR claims, most widely used is the Chain-ladder method and its modification presented by the Bornhuetter - Ferguson method. For modeling the outstanding claims, the available data should be presented in so called run-off triangle, which underlies in the basis of such methods. The present work provides a review of the algorithm for calculating insurance outstanding claim reserves according to the Chain-ladder method. Using available data for claims related to liability of drivers, registered in Bulgaria an example is constructed to illustrate the methodology of the Chain-Ladder method. Back-testing approach is used for validating the results.

  7. The Reserve's Medical Role for Homeland Security

    National Research Council Canada - National Science Library

    Magrane, John R., Jr

    2005-01-01

    ... to employ more elaborate methods such as dirty bombs, biological agents, and the use of chemicals. Such threats require local responders to use response strategies that meet these asymmetric challenges...

  8. Site environmental report for calendar year 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-08-01

    The purpose of this Site Environmental Report (SER) is to characterize site environmental management performance, confirm compliance with environmental standards and requirements, and highlight significant programs and efforts to the US Department of Energy (DOE) Strategic Petroleum Reserve (SPR). The SER, provided annually in accordance with DOE Order 5400.1, serves the public by summarizing monitoring data collected to assess how the SPR impacts the environment. The SER provides a balanced synopsis of non-radiological monitoring and regulatory compliance data and affirms that the SPR has been operating within acceptable regulatory limits.

  9. Biosphere reserves in action: Case studies of the American experience

    Energy Technology Data Exchange (ETDEWEB)

    None

    1995-06-26

    For nearly 20 years, biosphere reserves have offered a unique framework for building the knowledge, skills, and attitudes required for conservation and sustainable use of ecosystems. The 12 case studies in this volume chronicle many of the cooperative efforts to implement the biosphere reserve concept in the United States. Considered together, these efforts involve more than 20 types of protected areas, and the participation of all levels of government, and many private organizations, academic institutions, citizens groups, and individuals. Biosphere reserves are multi-purpose areas that are nominated by the national committee of the Man and the Biosphere Program (MAB) and designated by the United Nations Educational, Scientific and Cultural Organization (UNESCO) to serve as demonstration areas for cooperation in building harmonious relationships between human activities and the conservation of ecosystems and biological diversity. Each biosphere reserve exemplifies the characteristic ecosystems of one of the worlds biogeographical regions. It is a land or coas%arine area involving human communities as integral components and including resources managed for objectives ranging from complete protection to intensive, yet sustainable development. A biosphere reserve is envisioned as a regional ''landscape for learning'' in which monitoring, research, education, and training are encouraged to support sustainable conservation of natural and managed ecosystems. It is a framework for regional cooperation involving government decisionmakers, scientists, resource managers, private organizations and local people (i.e., the biosphere reserve ''stakeholders''). Finally, each biosphere reserve is part of a global network for sharing information and experience to help address complex problems of conservation and development. The 12 case studies presented in this report represent only a few of the possible evolutions of a biosphere reserve in

  10. 75 FR 24384 - Reserve Requirements of Depository Institutions Policy on Payment System Risk

    Science.gov (United States)

    2010-05-05

    ... manage their liquidity positions and interest-rate risk, and suggested maturities for term deposits..., resulting in a floating rate. Commenters supporting a floating rate suggested specific reference rates such... rates. The ``general level'' of short-term interest rates could include both fixed and floating rates...

  11. Reserve Component General and Flag Officers: A Review of Requirements and Authorized Strength

    Science.gov (United States)

    2016-01-01

    a senior civilian—SES, Defense Intelligence Senior Executive Service ( DISES ), or Defense Intelligence Senior Level (DISL). RAND researchers selected...serve as the superior of flag or general officers or SES civil - ians.3 It is also commonly held that a flag or general officer should be the superior...ing with allied and interagency communities on intelligence and counterintelligence issues, so any potential conversion to DISES /DISL would have to

  12. A Reservation Aggregation Framework Design for Demand Estimation

    Directory of Open Access Journals (Sweden)

    T. Vítek

    2006-01-01

    Full Text Available Effective management practices in the tourism and hotel area have seldom been more important than at the present time. Pricing decisions cannot be taken without serious thought. IT has provided the opportunity for a customer to make a quick market search and it offers decision support systems that can be used in the hotel management. The heart of yield management system consists of the predicting machine, which estimates the number of incoming reservations. Incoming reservations arrive randomly in time. The time series calculi as well as the estimators known from control engineering require properly defined time rows (with a constant period. This requirement is usually not fulfilled, so the input data are not exploited properly. This paper outlines a procedure that aggregates the reservations into a time series that is useful for demand prediction. The algorithm prepares the data systematically for further processing. Any method that process time rows can be used for subsequent prediction: time series, linear models or time extrapolation. 

  13. Petroleum reserves in West Africa: an overview

    International Nuclear Information System (INIS)

    Copinschi, Ph.; Favennec, J.P.

    1999-01-01

    The Gulf of Guinea region in West Africa is one in which production and reserves have increased the most during the last few years, essentially due to offshore operation. It is also there that the most spectacular discoveries have been made in recent years, particularly with deep-sea drilling. The low production costs and enthusiastic welcome for foreign investors make the region a favoured destination for large international companies, even if uncertainties and political tensions remain to make the situation delicate. In these conditions, the relationship between the host State and the foreign petrol companies are changing. Beyond the purely formal aspects of these new contacts, the whole former system of 'reserved markets' is being threatened by the increasing tendency to open the sector to competition. Eight countries are examined in detail: Nigeria, Angola, Gabon, Congo, Cameroon, Equatorial Guinea, the Ivory Coast and Chad. (authors)

  14. Reserve Component Personnel Issues: Questions and Answers

    Science.gov (United States)

    2017-01-18

    of one day of basic pay for each unit training assembly ( UTA ) they attend. A UTA is generally a four-hour period of instruction, and there are usually...training assembly ( UTA ), one point for each day of annual training (AT), and one point for each day of active duty. Points can also be earned for completing... on the vitality of the reserve components, such as funding, equipment, and personnel policy. This report is designed to provide an overview of key

  15. Developing Senior Leaders for the Reserve Components

    Science.gov (United States)

    2017-01-01

    For more information on the Forces and Resources Policy Center, see http://www.rand.org/nsrd/ndri/centers/frp.html or contact the director (contact information is provided on the web page ). ...some combination of experiences, education, and personal development. Each has an extensive concept of develop- ment—how they define it, what ...policy. First, in what ways can the develop- ment of RC senior leaders be improved? Second, in what ways can reserve component leader development

  16. User's guide for the Uranium Ore Reserve Calculation System (URAD)

    International Nuclear Information System (INIS)

    1988-12-01

    The URAD (Uranium Reserves and Data) system consists of four computer programs designed to facilitate the evaluation of uranium ore reserves analysis and the handling of basic uranium assay data. URAD is designed specifically as a training tool for anyone unfamiliar with the methodology, data requirements, and/or general computer applications in the field of uranium ore reserves analysis. However, it can effectively be used in a 'production' environment involving considerable amounts of data. The resulting programs are written in Microsoft FORTRAN (Version 3.1) and may be run on any IBM-compatible microcomputer under DOS 2.1 (or later). Only a basic working knowledge of DOS 2.1 is needed to maintain the system and run the programs. This guide includes the overview of the URAD system, the review of sample data and a complete description of the file structure and sample type formats of the basic sample data files. Program URDAT explains the initial processing of the primary UDAT files to obtain standard output listings and gamma-log interpretations of radiometric data, and to create intermediate UDAT files which are used by the ore reserves programs - RESUV, ORSAC, and SCOR. Figs and tabs

  17. Bilingualism, dementia, cognitive and neural reserve.

    Science.gov (United States)

    Perani, Daniela; Abutalebi, Jubin

    2015-12-01

    We discuss the role of bilingualism as a source of cognitive reserve and we propose the putative neural mechanisms through which lifelong bilingualism leads to a neural reserve that delays the onset of dementia. Recent findings highlight that the use of more than one language affects the human brain in terms of anatomo-structural changes. It is noteworthy that recent evidence from different places and cultures throughout the world points to a significant delay of dementia onset in bilingual/multilingual individuals. This delay has been reported not only for Alzheimer's dementia and its prodromal mild cognitive impairment phase, but also for other dementias such as vascular and fronto-temporal dementia, and was found to be independent of literacy, education and immigrant status. Lifelong bilingualism represents a powerful cognitive reserve delaying the onset of dementia by approximately 4 years. As to the causal mechanism, because speaking more than one language heavily relies upon executive control and attention, brain systems handling these functions are more developed in bilinguals resulting in increases of gray and white matter densities that may help protect from dementia onset. These neurocognitive benefits are even more prominent when second language proficiency and exposure are kept high throughout life.

  18. World energy demands and coal reserves

    Directory of Open Access Journals (Sweden)

    Ferenc Kovács

    2007-10-01

    Full Text Available On the basis of the expected increase in the world’s population and taking the estimated improvement in both technology and living standards into account, the paper forecasts energy demands. In 2000, actual energy consumption was 380-400 EJ.year-1, the forecast for the year 2050 is 600-1,050 EJ.year-1, while for the year 2100 it is 900-3,600 EJ.year-1. On the basis of the expected shares of the different fuels (coal, mineral oil, natural gas, nuclear energy, renewable energies, it can be assumed that in 2050 coal demand will be between 122-200 EJ.year-1 while the total coal demand for the 45 years ahead is estimated to be 5,500-6,900 EJ.year-1. This rate of demand basically involves an approximately 2 % increase every year.On the basis of data in relevant literature, the world’s coal reserves are: the industrial coal reserve is 800-1,000 · 109 tons, the geological stock is 5-15 1012 tons and the expected stock is 8-35 1012 tons. The world’s industrial coal reserve (which is economically exploitable at the present technological level guarantees supply for 200 years while the detected geological stock guarantees supply for a round 1,000 years.

  19. Disaggregating reserve-to-production ratios: An algorithm for United States oil and gas reserve development

    Science.gov (United States)

    Williams, Charles William

    Reserve-to-production ratios for oil and gas development are utilized by oil and gas producing states to monitor oil and gas reserve and production dynamics. These ratios are used to determine production levels for the manipulation of oil and gas prices while maintaining adequate reserves for future development. These aggregate reserve-to-production ratios do not provide information concerning development cost and the best time necessary to develop newly discovered reserves. Oil and gas reserves are a semi-finished inventory because development of the reserves must take place in order to implement production. These reserves are considered semi-finished in that they are not counted unless it is economically profitable to produce them. The development of these reserves is encouraged by profit maximization economic variables which must consider the legal, political, and geological aspects of a project. This development is comprised of a myriad of incremental operational decisions, each of which influences profit maximization. The primary purpose of this study was to provide a model for characterizing a single product multi-period inventory/production optimization problem from an unconstrained quantity of raw material which was produced and stored as inventory reserve. This optimization was determined by evaluating dynamic changes in new additions to reserves and the subsequent depletion of these reserves with the maximization of production. A secondary purpose was to determine an equation for exponential depletion of proved reserves which presented a more comprehensive representation of reserve-to-production ratio values than an inadequate and frequently used aggregate historical method. The final purpose of this study was to determine the most accurate delay time for a proved reserve to achieve maximum production. This calculated time provided a measure of the discounted cost and calculation of net present value for developing new reserves. This study concluded that

  20. Assessment of renewable energy reserves in Taiwan

    International Nuclear Information System (INIS)

    Chen, Falin; Lu, Shyi-Min; Tseng, Kuo-Tung; Wang, Eric; Lee, Si-Chen

    2010-01-01

    Since Taiwan imports more than 99% of energy supply from foreign countries, energy security has always been the first priority for government to formulate energy policy. The development of renewable energy not only contributes to the independence of energy supply, but also achieves benefits of economic development and environmental protection. Based upon information available to public, the present paper reassesses reserves of various renewable energies in Taiwan. The assessment includes seven kinds of renewable energies, namely, solar energy, wind power, biomass energy, wave energy, tidal energy, geothermal energy and hydropower, which are all commercialized and matured in terms of current technologies. Other renewable energies, which have not proven as matured as the aforementioned ones, are only assessed preliminarily in this paper, such as second generation of biomass, deep geothermal energy, the Kuroshio power generation and ocean thermal energy conversion. According to the estimation of this paper, the reserve of wind energy, up to 29.9 kWh/d/p (i.e., kWh per day per person), is the largest one among seven kinds of renewable energies in Taiwan, followed by 24.27 kWh/d/p of solar energy, 4.55 kWh/d/p of biomass, 4.58 kWh/d/p of ocean energy, 0.67 kWh/d/p of geothermal energy and 16.79 kWh/d/p of hydropower. If regarding biomass as a primary energy, and assuming 40% being the average efficiency to convert primary energy into electricity, the total power of the seven kinds of renewable energy reserves is about 78.03 kWh/d/p, which is equal to 2.75 times of 28.35 kWh/d/p of national power generation in 2008. If the reserves of 54.93 kWh/d/p estimated from other four kinds of renewable energies that have not technically matured yet are also taken into account, it will result that the reserves of renewable energy in Taiwan can be quite abundant. Although the results of the assessment point out that Taiwan has abundant renewable energy resources, the four inherent

  1. A Sensorless Power Reserve Control Strategy for Two-Stage Grid-Connected PV Systems

    DEFF Research Database (Denmark)

    Sangwongwanich, Ariya; Yang, Yongheng; Blaabjerg, Frede

    2017-01-01

    Due to the still increasing penetration of grid-connected Photovoltaic (PV) systems, advanced active power control functionalities have been introduced in grid regulations. A power reserve control, where namely the active power from the PV panels is reserved during operation, is required for grid...... to achieve the power reserve. In this method, the solar irradiance and temperature measurements that have been used in conventional power reserve control schemes to estimate the available PV power are not required, and thereby being a sensorless approach with reduced cost. Experimental tests have been...

  2. Unit commitment with probabilistic reserve: An IPSO approach

    International Nuclear Information System (INIS)

    Lee, Tsung-Ying; Chen, Chun-Lung

    2007-01-01

    This paper presents a new algorithm for solution of the nonlinear optimal scheduling problem. This algorithm is named the iteration particle swarm optimization (IPSO). A new index, called iteration best, is incorporated into particle swarm optimization (PSO) to improve the solution quality and computation efficiency. IPSO is applied to solve the unit commitment with probabilistic reserve problem of a power system. The outage cost as well as fuel cost of thermal units was considered in the unit commitment program to evaluate the level of spinning reserve. The optimal scheduling of on line generation units was reached while minimizing the sum of fuel cost and outage cost. A 48 unit power system was used as a numerical example to test the new algorithm. The optimal scheduling of on line generation units could be reached in the testing results while satisfying the requirement of the objective function

  3. Reserve Component Programs. Fiscal Year 1999 Report of the Reserve Forces Policy Board

    Science.gov (United States)

    2000-03-01

    Heavy Equipment Truck UH-1 Helicopter AH-1 Attack Helicopter PVS-5 Night Vision Goggles Army Reserve Dolly Sets Yard Truck Maintenance Contact...border collie instead of a propane canon, and agri- cultural outsourcing with 4-H sheep grazing. The Marine Corps Reserve continues to increase

  4. Parasite infection rates of impala (Aepyceros melampus) in fenced game reserves in relation to reserve characteristics

    Science.gov (United States)

    Ezenwa, V.O.

    2004-01-01

    Under certain conditions reserves can pose a threat to wildlife conservation by increasing the transmission of parasites and pathogens. In this study, I investigated associations between reserve characteristics including area, density and species richness and parasite infection rates in impala (Aepyceros melampus). Using coprological methods to measure gastrointestinal parasitism rates of impala inhabiting five fully or partially fenced game reserves in central Kenya, I found that bovid species richness was correlated with parasite taxa richness across reserves, and that prevalence rates of multi-host strongyle nematodes were higher in reserves with more species. In addition, reserve size was also implicated as a potential predictor of infection risk. Overall, these results suggest that wildlife inhabiting highly diverse and small reserves may suffer from higher than normal rates of infection. Given the potential debilitating effects increases in parasitism can have on wildlife, these results underscore the importance of considering parasite transmission dynamics in the management of small, fenced protected areas. ?? 2003 Elsevier Ltd. All rights reserved.

  5. Recent revisions of phosphate rock reserves and resources: a critique

    Science.gov (United States)

    Edixhoven, J. D.; Gupta, J.; Savenije, H. H. G.

    2014-12-01

    Phosphate rock (PR) is a finite mineral indispensable for fertilizer production, while P (phosphorus) is a major pollutant if applied or discharged in excess, causing widespread eutrophication (Carpenter and Bennet, 2011). High-grade PR is obtained from deposits which took millions of years to form and which are gradually being depleted. Recently, global PR reserves as reported by the US Geological Survey (USGS) have increased from 16 000 Mt PR in 2010 to 65 000 Mt PR in 2011 and further to 67 000 Mt PR in 2014. The majority of this 4-fold increase is based on a 2010 report by the International Fertilizer Development Center (IFDC), which increased Moroccan reserves from 5700 Mt PR as reported by USGS, to 51 000 Mt PR, reported as upgraded ("beneficiated") concentrate. The report also increased global resources from 163 000 Mt PR reported in the literature in 1989 to 290 000 Mt PR. IFDC used a simplified resource terminology which does not use the underlying thresholds for reserves and resources used in the USGS classification. IFDC proposed that agreement should be reached on PR resource terminology which should be as simple as possible. The report has profoundly influenced the PR scarcity debate, shifting the emphasis from resource scarcity to the pollution angle of the phosphate problem. In view of the high dependence of food production on PR and the importance of data on PR reserves and resources for scientific analysis and policy making, data on PR deposits should be transparent, comparable, reliable, and credible. We analyze (i) how IFDC's simplified terminology compares to international best practice in resource classification and whether it is likely to yield data that meet these requirements, (ii) whether the difference in volume between raw PR ore and upgraded PR concentrate is sufficiently noted in the literature, and (iii) whether the IFDC report presents an accurate picture of PR reserves and resources. We conclude that, while there is a global

  6. Medical Readiness of the Reserve Component

    Science.gov (United States)

    2012-01-01

    51 Some Dental Plans Are Cheaper—Comparison of Five Treatment Sources...in need of such care, 49 percent had more than one tooth needing treatment , 71 percent had periodontal disease, and 68 percent required one or more...preventive dental care, such as annual teeth cleaning (prophylaxis), fluo- ride treatment , and periodontal care. Complicated Nature of Medical Readiness

  7. 17 CFR 1.13 - [Reserved

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false 1.13 Section 1.13 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Minimum Financial and Related Reporting Requirements § 1.13 ...

  8. 17 CFR 1.11 - [Reserved

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false 1.11 Section 1.11 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Minimum Financial and Related Reporting Requirements § 1.11 ...

  9. Are Private Reserves Effective for Jaguar Conservation?

    Directory of Open Access Journals (Sweden)

    Carmina E Gutiérrez-González

    Full Text Available We present the first study of density and apparent survival for a jaguar (Panthera onca population in northern Mexico using 13 years of camera trap data from 2000 to 2012. We used the Barker robust design model which combines data from closed sampling periods and resight data between these periods to estimate apparent survival and abundance. We identified 467 jaguar pictures that corresponded to 48 jaguar individuals. We included camera type and field technician as covariates for detection probabilities. We used three covariates to evaluate the effect of reserve on jaguar apparent survival: i private reserve creation ii later reserve expansions, and iii cattle ranches' conservation activities. We found that the use of digital cameras in addition to film cameras increased detection probability by a factor of 6x compared with the use of only film cameras (p = 0.34 ± 0.05 and p = 0.05 ± 0.02 respectively in the closed period and more than three times in the open period (R = 0.91 ± 0.08 and R = 0.30 ± 0.13 mixed and film cameras respectively. Our availability estimates showed no temporary emigration and a fidelity probability of 1. Despite an increase of apparent survival probability from 0.47 ± 0.15 to 0.56 ± 0.11 after 2007, no single covariate explained the change in these point estimates. Mean jaguar density was 1.87 ± 0.47 jaguars/100 km2. We found that 13 years of jaguar population monitoring with our sampling size were not enough for detecting changes in survival or density. Our results provide a baseline for studies evaluating the effectiveness of protected areas and the inclusion of ranch owners in jaguar conservation programs and long-term population viability.

  10. Oak Ridge Reservation environmental report for 1992

    International Nuclear Information System (INIS)

    Koncinski, W.S.

    1993-09-01

    The two volumes of this report present data and supporting narratives regarding the impact of the US Department of Energy's (DOE's) Oak Ridge Reservation (ORR) on its environs and the public during 1992. Volume 1 includes all narrative descriptions, summaries, and conclusions and is intended to be a ''stand-alone'' report for the reader who does not want to review in detail all of the 1992 data for the ORR. This volume (volume 2) includes the detailed data in formats that ensure all the environmental data are presented. Narratives are not included in Vol. 2

  11. Flexible reserve markets for wind integration

    Science.gov (United States)

    Fernandez, Alisha R.

    The increased interconnection of variable generation has motivated the use of improved forecasting to more accurately predict future production with the purpose to lower total system costs for balancing when the expected output exceeds or falls short of the actual output. Forecasts are imperfect, and the forecast errors associated with utility-scale generation from variable generators need new balancing capabilities that cannot be handled by existing ancillary services. Our work focuses on strategies for integrating large amounts of wind generation under the flex reserve market, a market that would called upon for short-term energy services during an under or oversupply of wind generation to maintain electric grid reliability. The flex reserve market would be utilized for time intervals that fall in-between the current ancillary services markets that would be longer than second-to-second energy services for maintaining system frequency and shorter than reserve capacity services that are called upon for several minutes up to an hour during an unexpected contingency on the grid. In our work, the wind operator would access the flex reserve market as an energy service to correct for unanticipated forecast errors, akin to paying the generators participating in the market to increase generation during a shortfall or paying the other generators to decrease generation during an excess of wind generation. Such a market does not currently exist in the Mid-Atlantic United States. The Pennsylvania-New Jersey-Maryland Interconnection (PJM) is the Mid-Atlantic electric grid case study that was used to examine if a flex reserve market can be utilized for integrating large capacities of wind generation in a lowcost manner for those providing, purchasing and dispatching these short-term balancing services. The following work consists of three studies. The first examines the ability of a hydroelectric facility to provide short-term forecast error balancing services via a flex

  12. Oak Ridge Reservation environmental report for 1992

    International Nuclear Information System (INIS)

    Koncinski, W.S.

    1993-09-01

    The two volumes of this report present data and supporting narratives regarding the impact of the US Department of Energy's (DOE's) Oak Ridge Reservation (ORR) on its environs and the public during 1992. This Volume (Volume 1) includes all narrative descriptions, summaries, and conclusions and is intended to be a ''stand-alone'' report for the reader who does not want to review in detail all of the 1992 data for the ORR. Volume 2 includes the detailed data in formats that ensure all the environmental data are represented. Narratives are not included in Vol. 2

  13. Oak Ridge Reservation environmental report for 1991

    International Nuclear Information System (INIS)

    Mucke, P.C.

    1992-10-01

    The first two volumes of this report present data and supporting narratives regarding the impact of the US Department of Energy's (DOE's) Oak Ridge Reservation (ORR) on its surrounding environs and the public during 1991. Volume 1 includes all narrative descriptions, summaries, and conclusions and is intended to be a ''stand-alone'' report for the reader who does not want to review in detail all of the 1991 data for the ORR. This volume, Volume 2, includes the detailed data formats that ensure all the environmental data are represented. Narratives are not included. The information in Vol. 2 is addressed and analyzed in Vol. 1

  14. Oak Ridge Reservation environmental report for 1989

    International Nuclear Information System (INIS)

    Jacobs, V.A.; Wilson, A.R.

    1990-10-01

    This two-volume report, the Oak Ridge Reservation Environmental Report for 1989, is the nineteenth in an annual series that began in 1971. It reports the results of a comprehensive, year-round program to monitor the impact of operations at the three major US Department of Energy (DOE) production and research installations in Oak Ridge on the immediate areas' and surrounding region's groundwater and surface waters, soil, air quality, vegetation and wildlife, and through these multiple and varied pathways, the resident human population. Information is presented for the environmental monitoring Quality Assurance (QA) Program, audits and reviews, waste management activities, land special environmental studies. Data are included for the Oak Ridge Y-12 Plant, Oak Ridge National Laboratory (ORNL), and Oak Ridge Gaseous Diffusion Plant (ORGDP). Volume 1 presents narratives, summaries, and conclusions based on environmental monitoring at the three DOE installations and in the surrounding environs during calendar year (CY) 1989. Volume 1 is intended to be a ''stand-alone'' report about the Oak Ridge Reservation (ORR) for the reader who does not want an in-depth review of 1989 data. Volume 2 presents the detailed data from which these conclusions have been drawn and should be used in conjunction with Volume 1

  15. Extrapolating phosphorus production to estimate resource reserves.

    Science.gov (United States)

    Vaccari, David A; Strigul, Nikolay

    2011-08-01

    Various indicators of resource scarcity and methods for extrapolating resource availability are examined for phosphorus. These include resource lifetime, and trends in resource price, ore grade and discovery rates, and Hubbert curve extrapolation. Several of these indicate increasing scarcity of phosphate resources. Calculated resource lifetime is subject to a number of caveats such as unanticipated future changes in resource discovery, mining and beneficiation technology, population growth or per-capita demand. Thus it should be used only as a rough planning index or as a relative indicator of potential scarcity. This paper examines the uncertainty in one method for estimating available resources from historical production data. The confidence intervals for the parameters and predictions of the Hubbert curves are computed as they relate to the amount of information available. These show that Hubbert-type extrapolations are not robust for predicting the ultimately recoverable reserves or year of peak production of phosphate rock. Previous successes of the Hubbert curve are for cases in which there exist alternative resources, which is not the situation for phosphate. It is suggested that data other than historical production, such as population growth, identified resources and economic factors, should be included in making such forecasts. Copyright © 2011 Elsevier Ltd. All rights reserved.

  16. Oak Ridge Reservation environmental report for 1989

    Energy Technology Data Exchange (ETDEWEB)

    Jacobs, V.A.; Wilson, A.R. (eds.)

    1990-10-01

    This two-volume report, the Oak Ridge Reservation Environmental Report for 1989, is the nineteenth in an annual series that began in 1971. It reports the results of a comprehensive, year-round program to monitor the impact of operations at the three major US Department of Energy (DOE) production and research installations in Oak Ridge on the immediate areas' and surrounding region's groundwater and surface waters, soil, air quality, vegetation and wildlife, and through these multiple and varied pathways, the resident human population. Information is presented for the environmental monitoring Quality Assurance (QA) Program, audits and reviews, waste management activities, land special environmental studies. Data are included for the Oak Ridge Y-12 Plant, Oak Ridge National Laboratory (ORNL), and Oak Ridge Gaseous Diffusion Plant (ORGDP). Volume 1 presents narratives, summaries, and conclusions based on environmental monitoring at the three DOE installations and in the surrounding environs during calendar year (CY) 1989. Volume 1 is intended to be a stand-alone'' report about the Oak Ridge Reservation (ORR) for the reader who does not want an in-depth review of 1989 data. Volume 2 presents the detailed data from which these conclusions have been drawn and should be used in conjunction with Volume 1.

  17. International standardisation for the reporting of resources and reserves

    International Nuclear Information System (INIS)

    Farmer, K.

    2014-01-01

    ), Canada (CIM), Europe (PERC), Russia (NAEN), South Africa (SAMREC) and the USA (SME). The member NROs nominate representatives to the Committee. The top 5 listed mining companies in the world all report their resources and reserves in accordance with the CRIRSCO family of codes. Two of which, BHP Billiton and Rio Tinto are uranium producers. It is noteworthy that prior to the inclusion in 2010 of the Russian NAEN code in the CRIRSCO family the combined value of mining companies listed on stock exchanges of CRIRSCO member countries accounted for more than 80% of the listed capital of the mining industry. Mineral resource and Ore Reserve codes are the basic building block underpinning the confidence required for investment in the mineral resources sector. They are the basis for our decisions when evaluating or selling projects. (author)

  18. 75 FR 67731 - Federal Reserve Bank Services

    Science.gov (United States)

    2010-11-03

    ... capital asset pricing model (CAPM). In the CAPM, the required rate of return on a firm's equity is equal to the return on a risk-free asset plus a risk premium. To implement the CAPM, the risk- free rate is... premium). The 2011 after- tax CAPM ROE is calculated as 0.16% + (1 * 5.88%) = 6.04%. Using a tax rate of...

  19. Environmental Compliance Assessment for Army Reserves (ECAAR)

    Science.gov (United States)

    1991-11-01

    COMMCACF/LOCATION CODE (1) MUSARC Engineer/Facility Coordinator (2) Facility Manager (3) Shop r rcia (5) Directorae of Engincering and Housiig (DEIl...completed recently or cine personnel at each has been updated recently. (1)(2) installation are required to conduct and maintain Examine emission inventory...facility corn- mander (AR 200-1, 8-4 [h][12]). I) UISARC rigi,.r/Faility Cokxdtinattr (2) Fadlity Manager (5) Directorae o" F.gineaing and Imirg (DEHI

  20. STEM Summer Academy on the Navajo Reservation

    Science.gov (United States)

    Alexander, C. J.

    2012-12-01

    The US Rosetta Project is the NASA contribution to the International Rosetta Mission, an ESA cornerstone mission to comet Churyumov-Gerasimenko. While the project's outreach efforts span multi-media, and a variety of age and ethnic groups, a special emphasis has been made to find a way to provide meaningful outreach to the reservation communities. Because language preservation is an issue of urgent concern to the reservation communities, and because Rosetta, uniquely among NASA missions, has been named after the notion that keys to missing understanding of elements of the ancient past were found in the language on the original Rosetta stone, the US Rosetta Project has embarked upon outreach with a focus on STEM vocabulary in ancient US languages of the Navajo, Hopi, Ojibwe, and other tribal communities as the project expands. NASA image and science are used and described in the native language, alongside lay English and scientific English curriculum elements. Additionally, science (geology/chemistry/botany/physics) elements drawn from the reservation environment, including geomorphology, geochemistry, soil physics, are included and discussed in the native language as much as possible — with their analogs in other planetary environments (such as Mars). In this paper we will report on the most recent Summer Science Academy [2012], a four week summer course for middle school children, created in collaboration with teachers and administrators in the Chinle Unified School District. The concept of the Academy was initiated in 2011, and the first Academy was conducted shortly thereafter, in June 2011 with 14 children, 3 instructors, and a NASA teacher workshop. The community requested three topics: geology, astronomy, and botany. The 2012 Academy built on the curriculum already developed with more robust field trips, addressed to specific science topics, additional quantitative measurements and activities, with more written material for the cultural components from

  1. Revner, sprækker, skred

    DEFF Research Database (Denmark)

    Mønster, Louise

    2010-01-01

    The article analyses short stories by Helle Helle, Pia Juul and Naja Marie Aidt which address family and love relations, and it discusses the way in which they relate to presentations of new Danish literature. It is argued that these short stories are typical for the first decade of the 21th...

  2. Cost Analysis of Maintenance Programs for Pre-Positioned War Reserve Material Stock (PWRMS)

    National Research Council Canada - National Science Library

    Cyr, Phillip

    2002-01-01

    ...) for that maintenance. The objective is to provide DoD, the Navy, and the Civil Engineer Corps a guideline and possible benchmark for maintenance costs required to maintain the CESE War Reserves in a Cl condition of readiness...

  3. Oak Ridge Reservation environmental report for 1991

    International Nuclear Information System (INIS)

    Mucke, P.C.

    1992-10-01

    The Oak Ridge Reservation Environmental Report for 1991 is the 21st in a series that began in 1971. The report documents the annual results of a comprehensive program to estimate the impact of the US Department of Energy (DOE) Oak Ridge operations upon human health and the environment. The report is organized into ten sections that address various aspects of effluent monitoring, environmental surveillance, dose assessment, waste management, and quality assurance. A compliance summary gives a synopsis of the status of each facility relative to applicable state and federal regulations. Data are included for the following: Oak Ridge Y-12 Plant; Oak Ridge National Laboratory (ORNL); and Oak Ridge K-25 Site. Effluent monitoring and environmental surveillance programs are intended to serve as effective indicators of contaminant releases and ambient contaminant concentrations that have the potential to result in adverse impacts to human health and the environment

  4. Independents add gas reserves, forego romance

    Energy Technology Data Exchange (ETDEWEB)

    Gill, D.

    1981-08-01

    Incentive pricing for low-permeability reservoirs and tax advantages for drilling them are 2 big reasons why more independents may start making a special effort to add gas reserves to their inventories. If so, it will be a change from past practices, which saw independents build up big gas positions by circumstance rather than by intention. There are always major refiners ready and willing to buy whole crude oil reservoirs from small producers, but purchasers willing to take gas fields in a single investment are few and far between. Lower-than-normal return on equity during the first 20 years, plus the heavy front-end cost of a frac necessary to produce the tight gas might dissuade independents from drilling tight gas sands, but those liabilities are offset by the higher price tight gas gets and the peculiar tax advantages of exploring for it that make a nice fit with the small operator's way of doing business.

  5. Coronary flow velocity reserve by echocardiography

    DEFF Research Database (Denmark)

    Olsen, Rasmus Huan; Pedersen, Lene Rørholm; Snoer, Martin

    2016-01-01

    reserve (MFR) measured by PET in overweight and obese patients. METHODS: Participants with revascularized coronary artery disease were examined by CFVR. Subgroups were examined by repeated CFVR (reproducibility) or Rubidium-82-PET (agreement). To account for time variation, results were computed for scans...... %, and reliability 0.97. Agreement with MFR of the LAD territory (n = 35) was without significant bias and overall LOA were (-1.40;1.46). Agreement was best for examinations performed within 1-week of participants without MI of the LAD-territory (n = 12); LOA = (-0.68;0.88). CONCLUSIONS: CFVR was highly feasible...... with a good reproducibility on par with other contemporary measures applied in cardiology. Agreement with MFR was acceptable, though discrepancy related to prior MI has to be considered. CFVR of LAD is a valid tool in overweight and obese patients....

  6. Oak Ridge Reservation environmental report for 1988

    International Nuclear Information System (INIS)

    Prince, N.L.

    1989-05-01

    The first two volumes of this report are devoted to a presentation of environmental data and supporting narratives for the US Department of Energy's (DOE's) Oak Ridge Reservation (ORR) and surrounding environs during 1988. Volume 1 includes all narrative descriptions, summaries, and conclusions and is intended to be a ''stand-alone'' report for the ORR for the reader who does not want to review in detail all of the 1988 data. Volume 2 includes the detailed data summarized in a format to ensure that all environmental data are represented in the tables. Narratives are not included in Volume 2. The tables in Volume 2 are addressed in Volume 1. For this reason, Vol. 2 cannot be considered a stand-alone report but is intended to be used in conjunction with Volume 1

  7. Oil reserves are a dynamic quantity

    International Nuclear Information System (INIS)

    Aeberli, O. E.

    2006-01-01

    In this exclusive interview with Rolf Hartl, head of the Oil Association of Switzerland, questions on developments in the consumption area and on future perspectives for the oil business are dealt with. The extent of oil reserves is looked at and the opinions of various experts on the subject are discussed. The 'energy-hunger' of China and third-world countries is discussed and the question is asked as to whether the maximum of oil-extraction has already been reached. Price developments and their possible effect on consumption are discussed, as are the effects of political conflicts on price developments. Finally, perspectives for the development of new oil discoveries are looked at

  8. Macrofungi of the Zasavica special nature reserve

    Directory of Open Access Journals (Sweden)

    Cvijanović Marko S.

    2009-01-01

    Full Text Available In the frame of biodiversity investigation of the Republic of Serbia, the investigation of the presence and the diversity of macrofungi of the Zasavica Special Nature Reserve (North Serbia has been undertaken. Relatively poor generic diversity of macrofungi was recorded with domination of ecological group of wood-decaying species. Even though being preliminary, our results point to the necessity of conservation and protection of recent fungal diversity but, in our opinion, not by making a so-called 'Red list of endangered species', which, due to the lack of information and very poor evidence on this group of organisms in our country, are extremely unreliable and therefore disputable, but rather through the very short list of a few not endangered species, conditionally called 'White list of not endangered fungal species', if such species recently exist et all.

  9. Aksu-Zhabagly Nature Reserve's 90-anniversary

    Directory of Open Access Journals (Sweden)

    Anatoliy F. Kovshar

    2016-05-01

    Full Text Available The Aksu-Zhabagly nature reserve is located in West Tien Shan in Kazakhstan, on the border of three countries – Kazakhstan, Kyrgyzstan and Uzbekistan (70°18'-57' E and 42°08'-30' N, with an area of 1281 km2; its length is 53 km from the most western to the most eastern point and 41 km from the most southern to the most northern point. It occupies the western limit of the Talasskiy Alatau ridge and its north-western spurs: Zhabaglytau mountains, Alatau, Bugultor, Aksutau and Ugam ridges. In the neighbouring Karatau ridge there is a palaeontological site with an area of 2.2 km2 with deposits of flora and fauna of the Jurassic period. The absolute heights above sea level are 1300–4200 m. The relief is alpine – deep canyons with steep slopes. The middle mountain zone (1300–2000 m is occupied by meadow-steppe formations with juniper sparse forests (Juniperus semiglobosa, J. seravschanica; subalpine meadows (2000–3000 m are alternated by creeping juniper thickets (Juniperus turkestanica and rocky outcrops; the alpine zone (higher than 3000 m is dominated by rocks and snowfields, and glaciers above 3500 m. The nature reserve's flora constitutes almost half of all West Tien Shan's flora and counts 1737 species, including: 235 species of fungi, 64 lichens, 63 species each of algae and mosses, as well as 1312 species of higher plants. Among those, 200 species are medicinal and 57 species are listed in the Red Data Books of Kazakhstan, Uzbekistan and Kyrgyzstan. The vertebrates fauna includes 320 species: mammals – 52 species, birds – 247 (130 of them are nesting, reptiles and amphibians – 14, fishes – 7 species. Animals inhabiting the territory include argali (Ovis ammon karelini, mountain goat (Capra sibirica, bear (Ursus arctos isabellinus, snow leopart (Uncia uncia, Turkestan lynx (Lynx lynx isabellinus; birds – bearded vulture (Gypaёtus barbatus, Himalayan snowcock (Tetraogallus himalayensis, chukar (Alectoris chukar, blue

  10. Oak Ridge Reservation environmental report for 1989

    Energy Technology Data Exchange (ETDEWEB)

    Jacobs, V.A.; Wilson, A.R. (eds.)

    1990-10-01

    The first two volumes of this report are devoted to a presentation of environmental data and supporting narratives for the US Department of Energy's (DOE's) Oak Ridge Reservation (ORR) and surrounding environs during 1989. Volume 1 includes all narrative descriptions, summaries, and conclusions and is intended to be a stand-alone'' report for the ORR for the reader who does not want to review in detail all of the 1989 data. Volume 2 includes the detailed data summarized in a format to ensure that all environmental data are represented in the tables. Narratives are not included in Vol. 2. The tables in Vol. 2 are addressed in Vol. 1. For this reason, Vol. 2 cannot be considered a stand-alone report but is intended to be used in conjunction with Vol. 1. 16 figs., 194 tabs.

  11. Radioactive waste management at the Hanford Reservation

    International Nuclear Information System (INIS)

    Anon.

    1979-01-01

    During some 30 years of plutonium production, the Hanford Reservation has accumulated large quantities of low- and high-level radioactive wastes. The high-level wastes have been stored in underground tanks, and the low-level wastes have been percolated into the soil. In recent years some programs for solidification and separation of the high-level wastes have been initiated. The Hanford waste-management system was studied by a panel of the Committee on Radioactive Waste Management of the National Academy of Sciences. The panel concluded that Hanford waste-management practices were adequate at present and for the immediate future but recommended increased research and development programs related to long-term isolation of the wastes. The panel also considered some alternatives for on-site disposal of the wastes. The Hanford Reservation was originally established for the production of plutonium for military purposes. During more than 30 years of operation, large volumes of high- and low-level radioactive wastes have been accumulated and contained at the site. The Management of these wastes has been the subject of controversy and criticism. To obtain a true technical evaluation of the Hanford waste situation, the Energy Research and Development Administration (now part of the Department of Energy) issued a contract to the National Academy of Sciences and the National Research Councilto conduct an independent review and evaluation of the Hanford waste-management practices and plans. A panel of the Committee on Radioactive Waste Management (CRWM) of the National Academy of Sciences conducted this study between the summer of 1976 and the summer of 1977. This article is a summary of the final report of that panel

  12. A study of the effects of enhanced oil recovery agents on the quality of Strategic Petroleum Reserves crude oil. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Kabadi, V.N.

    1992-10-01

    The project was initiated on September 1, 1990. The objective of the project was to carry out a literature search to estimate the types and extents of long time interactions of enhanced oil recovery (EOR) agents, such as surfactants, caustics and polymers, with crude oil. This information is necessary to make recommendations about mixing EOR crude oil with crude oils from primary and secondary recovery processes in the Strategic Petroleum Reserve (SPR). Data were sought on both adverse and beneficial effects of EOR agents that would impact handling, transportation and refining of crude oil. An extensive literature search has been completed, and the following informations has been compiled: (1) a listing of existing EOR test and field projects; (2) a listing of currently used EOR agents; and (3) evidence of short and long term physical and chemical interactions of these EOR-agents with hydrocarbons, and their effects on the quality of crude oil at long times. This information is presented in this report. Finally some conclusions are derived and recommendations are made. Although the conclusions are based mostly on extrapolations because of lack of specific data, it is recommended that the enhancement of the rates of biodegradation of oil catalyzed by the EOR agents needs to be further studied. There is no evidence of substantial long term effects on crude oil because of other interactions. Some recommendations are also made regarding the types of studies that would be necessary to determine the effect of certain EOR agents on the rates of biodegradation of crude oil.

  13. Interactions between the German Electricity Spot Market and the Reserve Energy Market

    International Nuclear Information System (INIS)

    Graeber, Bernhardt

    2005-01-01

    Eight years after market opening, Germany has well established spot and future markets for electricity. Besides OTC and Internet broker platforms the main market place is the European Energy Exchange in Leipzig (EEX) with its spot and future market. Less known is the reserve energy market in Germany. The four German transmission system operators (TSOs) EnBW, EON, RWE and Vattenfall purchase network services on the reserve energy market. Products with specific technical requirements are primary, secondary and tertiary reserve. (Details about the technical requirements and typical means for providing the required services will be presented.) Each TSO organises a separate auction for these products - for primary and secondary reserve half-yearly, for tertiary reserve daily. Due to the technical requirements the liquidity on these markets is limited, but especially on the tertiary reserve market it is recently growing significantly due to new participants marketing several smaller municipal and industrial reserve power plants as combined bids which meet the 30 MW min. capacity requirement. Every power plant or interruptible load could not only be offered as capacity on the reserve market but could also be dispatched for the spot market. Therefore the developments of prices on these markets are not independent and opportunity costs against the spot market can be estimated for different type of plants bidding in the reserve market. Another interaction between reserve and spot market is caused by the balancing price system in Germany. Prices for balancing energy meeting deviations between load, trading balance and production of a market participant are based on quarter-hourly reserve energy costs encountered by the TSO. As unbiased load and production forecasts are not strictly enforced by the TSOs so far, part of the planned demand could be met with balancing energy if EEX spot market prices rise above expected balancing energy prices. This interrelationship has a

  14. Impact of joint statistical dual-energy CT reconstruction of proton stopping power images: comparison to image- and sinogram-domain material decomposition approaches.

    Science.gov (United States)

    Zhang, Shuangyue; Han, Dong; Politte, David G; Williamson, Jeffrey F; O'Sullivan, Joseph A

    2018-03-23

    To assess the performance of a novel dual-energy CT (DECT) approach for proton stopping power ratio (SPR) mapping that integrates image reconstruction andmaterial characterization using a joint statistical image reconstruction (JSIR) method based on a linear basis vector model (BVM). A systematic comparison between the JSIR-BVM method and previously described DECT image- and sinogram-domain decomposition approaches is also carried out on synthetic data. The JSIR-BVM method was implemented to estimate the electron densities and mean excitation energies (I-values) required by the Bethe equation for SPR mapping. In addition, image- and sinogram-domain DECT methods based on three available SPR models including BVM were implemented for comparison. The intrinsic SPR modeling accuracy of the three models was first validated. Synthetic DECT transmission sinograms of two 330 mm diameter phantoms each containing 17 soft and bony tissues (for a total of 34) of known composition were then generated with spectra of 90 and 140 kVp. The estimation accuracy of the reconstructed SPR images were evaluated for the seven investigated methods. The impact of phantom size and insert location on SPR estimation accuracy was also investigated. All three selected DECT-SPR models predict the SPR of all tissue types with less than 0:2% RMS errors under idealized conditions with no reconstruction uncertainties. When applied to synthetic sinograms, the JSIR-BVM method achieves the best performance with mean and RMS-average errors of less than 0:05% and 0:3%, respectively, for all noise levels, while the image- and sinogram-domain decomposition methods show increasing mean and RMS-average errors with increasing noise level. The JSIR-BVM method also reduces statistical SPR variation by six-fold compared to other methods. A 25% phantom diameter change causes up to 4% SPR differences for the image-domain decomposition approach, while the JSIR-BVM method and sinogram-domain decomposition methods are

  15. SCPR: Secure Crowdsourcing-Based Parking Reservation System

    Directory of Open Access Journals (Sweden)

    Changsheng Wan

    2017-01-01

    Full Text Available The crowdsourcing-based parking reservation system is a new computing paradigm, where private owners can rent their parking spots out. Security is the main concern for parking reservation systems. However, current schemes cannot provide user privacy protection for drivers and have no key agreement functions, resulting in a lot of security problems. Moreover, current schemes are typically based on the time-consuming bilinear pairing and not suitable for real-time applications. To solve these security and efficiency problems, we present a novel security protocol with user privacy called SCPR. Similar to protocols of this field, SCPR can authenticate drivers involved in the parking reservation system. However, different from other well-known approaches, SCPR uses pseudonyms instead of real identities for providing user privacy protection for drivers and designs a novel pseudonym-based key agreement protocol. Finally, to reduce the time cost, SCPR designs several novel cryptographic algorithms based on the algebraic signature technique. By doing so, SCPR can satisfy a number of security requirements and enjoy high efficiency. Experimental results show SCPR is feasible for real world applications.

  16. Cognitive reserve, cortical plasticity and resistance to Alzheimer's disease.

    Science.gov (United States)

    Esiri, Margaret M; Chance, Steven A

    2012-03-01

    There are aspects of the ageing brain and cognition that remain poorly understood despite intensive efforts to understand how they are related. Cognitive reserve is the concept that has been developed to explain how it is that some elderly people with extensive neuropathology associated with dementia show little in the way of cognitive decline. Cognitive reserve is intimately related to cortical plasticity but this also, as it relates to ageing, remains poorly understood at the present time. Despite the shortcomings in understanding, we do have some knowledge on which to base efforts to minimise the likelihood of an elderly person developing dementia. For some risks the evidence is far from secure, but resistance to Alzheimer's disease (AD) appears from epidemiological studies to be contributed to by avoiding hypertension in middle life, obesity, depression, smoking and diabetes and head injury and by undertaking extended years of education, physical exercise, and social and intellectual pursuits in middle and late life. Nutritional factors may also promote healthy brain ageing. Resistance to AD is also contributed to by genetic factors, particularly apolipoprotein E2, but some combinations of other genetic polymorphisms as well. Although multiple factors and possible interventions may influence cognitive reserve and susceptibility to dementia, much more work is required on the mechanisms of action in order to determine which, if any, may improve the clinical and epidemiological picture. Understanding of how such factors operate may lead to new initiatives to keep the elderly population in the 21st century able to lead active and fulfilling lives.

  17. INTERNATIONAL RESERVES, GUARANTEE THAT SUPPORTS ROMANIA'S ECONOMIC DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    MEDAR LUCIAN-ION

    2014-10-01

    Full Text Available Aggregate demand in our country far exceeds the ability of the economy to produce goods and services. The gap between total demand for goods and services on the one hand and economic status, on the other hand stands out primarily by the continuing need for funds to cover the budget deficit. The Lack of foreign investors, poor development of capital market and non-involvement of credit institutions to support economic development leads the Romanian state to borrow regularly on international money market. Guarantor of the country for these loans is the reserve fund managed by the central bank of the state. Trade deficits and foreign borrowing are two components of the same problems. As the state borrows more from the international financial markets the higher is the trade deficit. A national initiative on facilities development companies with export production and aggregate demand for domestic products, can lead to lower imports. Increasing the fund's reserves and activation may be one of the solutions required to support economic development. Through this study we try to discover the role of the reserve fund and other sources of economic development.

  18. QoS routing via multiple paths using bandwidth reservation

    Energy Technology Data Exchange (ETDEWEB)

    Rao, N.S.V.; Batsell, S.G.

    1997-11-01

    The authors address the problem of computing a multipath, consisting of possibly overlapping paths, to transmit data from the source node s to the destination node d over a computer network while ensuring deterministic bounds on end-to-end delay or delivery rate. They consider two generic routing problems within the framework wherein bandwidth can be reserved, and guaranteed, once reserved, on various links of the communication network. The first problem requires that a message of finite length be transmitted from s to d within {tau} units of time. The second problem requires that a sequential message of r units be transmitted at a rate of {eta} such that maximum time difference between two units that are received out of order is no more than q. They propose a polynomial-time algorithm to the first problem based on an adaptation of the classical Ford-Fulkerson`s method. They present simulation results to illustrate the applicability of the proposed algorithm. They show the second problem to be NP-complete and propose a polynomial-time approximate solution.

  19. QoS routing via multiple paths using bandwidth reservation

    Energy Technology Data Exchange (ETDEWEB)

    Rao, N.S.V.; Batsell, S.G.

    1998-01-01

    The authors address the problem of computing a multipath, consisting of possibly overlapping paths, to transmit data from the source node s to the destination node d over a computer network while ensuring deterministic bounds on end-to-end delay or delivery rate.They consider two generic routing problems within the framework wherein bandwidth can be reserved, and guaranteed, once reserved, on various links of the communication network. The first problem requires that a message of finite length be transmitted from s to d within {tau} units of time. The second problem requires that a sequential message of r units be transmitted at a rate of {eta} such that maximum time difference between two units that are received out of order is no more than q. They propose a polynomial-time algorithm to the first problem based on an adaptation of the classical Ford-Fulkerson`s method. They present simulation results to illustrate the applicability of the proposed algorithm. They show the second problem to be NP-complete, and propose a polynomial-time approximately solution.

  20. Assessing reserve-building pursuits and person characteristics: psychometric validation of the Reserve-Building Measure.

    Science.gov (United States)

    Schwartz, Carolyn E; Michael, Wesley; Zhang, Jie; Rapkin, Bruce D; Sprangers, Mirjam A G

    2018-02-01

    A growing body of research suggests that regularly engaging in stimulating activities across multiple domains-physical, cultural, intellectual, communal, and spiritual-builds resilience. This project investigated the psychometric characteristics of the DeltaQuest Reserve-Building Measure for use in prospective research. The study included Rare Patient Voice panel participants. The web-based survey included the Reserve-Building Measure with one-week re-test, measures of quality of life (QOL) and well-being (PROMIS General Health; NeuroQOL Cognitive Function and Positive Affect & Well-Being short-forms; Ryff Environmental Mastery subscale); and the Big Five Inventory-10 personality measure. Classical test theory and item response theory (IRT) analyses investigated psychometric characteristics of the Reserve-Building Measure. This North American sample (n = 592) included both patients and caregivers [mean age = 44, SD 19)]. Psychometric analyses revealed distinct subscales measuring current reserve-building activities (Active in the World, Games, Outdoors, Creative, Religious/Spiritual, Exercise, Inner Life, Shopping/Cooking, Passive Media Consumption,), past reserve-building activities (Childhood Activities, Achievement), and reserve-related person-factors (Perseverance, Current and Past Social Support, and Work Value). Test-retest stability (n = 101) was moderately high for 11 of 15 subscales (ICC range 0.78-0.99); four were below 0.59 indicating a need for further refinement. IRT analyses supported the item functioning of all subscales. Correlational analyses suggest the measure's subscales tap distinct constructs (range r = 0.11-0.46) which are not redundant with QOL, well-being, or personality (range r = 0.11-0.48). The Reserve-Building Measure provides a measure of activities and person-factors related to reserve that may potentially be useful in prospective research.