Desirable Strategic Petroleum Reserves policies in response to supply uncertainty: A stochastic analysis

International Nuclear Information System (INIS)

Bai, Yang; Zhou, Peng; Tian, Lixin; Meng, Fanyi

2016-01-01

Highlights: • A stochastic model is proposed to study Strategic Petroleum Reserves (SPR) policy. • The model aims to find desirable SPR size, acquisition, drawdown and refilling policy. • The impact of SPR policy and supply disruption on oil price has been examined. - Abstract: The paper proposes a survey on three issues related to Strategic Petroleum Reserves (SPR) policy. Firstly, what are the optimal SPR acquisition, drawdown and refilling policy in response to various market risks? Secondly, how SPR policy or actions will affect the market factors, i.e. oil demand or price. Thirdly, in what extend a disruption may induce price shock. For the purpose, the study proposed a Markov Decision Process model (SPR-MDP). In the model, oil supply, disruption size and duration are considered to be highly stochastic. Oil price is determined by market fundamentals exclusively. According to the empirical study, we come to some interesting conclusions. Firstly, oil price and disruption risk show different ways in influencing the desirable SPR size. It is found that the SPR size increases with the decrease of oil price while increase of disruption risk. Secondly, SPR acquisition may increase oil price slightly by influencing the basic fundamentals. In given case, we find acquisition of 7 million barrels per month increase the price by 2.6%. But the influence weakens with decrease of acquisition size. Thirdly, disruption duration shows significant impact on SPR drawdown policy. In a two-month disruption case, it is found that 51% of SPR should be released in the first month. Another 40% is released in the following month. The other 9% SPR is left for forthcoming disruptions. Meanwhile, SPR drawdown shows high efficient in damping oil price in the disruption. In given case, after drawdown of SPR, the oil prices only increases by 0.7% in the second month though continue disruption.

Fabrication and characterization of SPR chips with the modified bovine serum albumin

Science.gov (United States)

Chen, Xing; Zhang, Lu-lu; Cui, Da-fu

2016-03-01

A facile surface plasmon resonance (SPR) chip is developed for small molecule determination and analysis. The SPR chip was prepared based on a self assembling principle, in which the modified bovine serum albumin (BSA) was directly self-assembled onto the bare gold surface. The surface morphology of the chip with the modified BSA was investigated by atomic force microscopy (AFM) and its optical properties were characterized. The surface binding capacity of the bare facile SPR chip with a uniform morphology is 8 times of that of the bare control SPR chip. Based on the experiments of immune reaction between cortisol antibody and cortisol derivative, the sensitivity of the facile SPR chip with the modified BSA is much higher than that of the control SPR chip with the un-modified BSA. The facile SPR chip has been successfully used to detect small molecules. The lowest detection limit is 5 ng/mL with a linear range of 5—100 ng/mL for cortisol analysis. The novel facile SPR chip can also be applied to detect other small molecules.

Two-Channel SPR Sensor Combined Application of Polymer- and Vitreous-Clad Optic Fibers

Directory of Open Access Journals (Sweden)

Yong Wei

2017-12-01

Full Text Available By combining a polymer-clad optic fiber and a vitreous-clad optic fiber, we proposed and fabricated a novel optic fiber surface plasmon resonance (SPR sensor to conduct two-channel sensing at the same detection area. The traditional optic fiber SPR sensor has many disadvantages; for example, removing the cladding requires corrosion, operating it is dangerous, adjusting the dynamic response range is hard, and producing different resonance wavelengths in the sensing area to realize a multi-channel measurement is difficult. Therefore, in this paper, we skillfully used bare fiber grinding technology and reverse symmetry welding technology to remove the cladding in a multi-mode fiber and expose the evanescent field. On the basis of investigating the effect of the grinding angle on the dynamic range change of the SPR resonance valley wavelength and sensitivity, we combined polymer-clad fiber and vitreous-clad fiber by a smart design structure to realize at a single point a two-channel measurement fiber SPR sensor. In this paper, we obtained a beautiful spectral curve from a multi-mode fiber two-channel SPR sensor. In the detection range of the refractive rate between 1.333 RIU and 1.385 RIU, the resonance valley wavelength of channel Ⅰ shifted from 622 nm to 724 nm with a mean average sensitivity of 1961 nm/RIU and the resonance valley wavelength of channel Ⅱ shifted from 741 nm to 976 nm with a mean average sensitivity of 4519 nm/RIU.

Two-Channel SPR Sensor Combined Application of Polymer- and Vitreous-Clad Optic Fibers.

Science.gov (United States)

Wei, Yong; Su, Yudong; Liu, Chunlan; Nie, Xiangfei; Liu, Zhihai; Zhang, Yu; Zhang, Yonghui

2017-12-09

By combining a polymer-clad optic fiber and a vitreous-clad optic fiber, we proposed and fabricated a novel optic fiber surface plasmon resonance (SPR) sensor to conduct two-channel sensing at the same detection area. The traditional optic fiber SPR sensor has many disadvantages; for example, removing the cladding requires corrosion, operating it is dangerous, adjusting the dynamic response range is hard, and producing different resonance wavelengths in the sensing area to realize a multi-channel measurement is difficult. Therefore, in this paper, we skillfully used bare fiber grinding technology and reverse symmetry welding technology to remove the cladding in a multi-mode fiber and expose the evanescent field. On the basis of investigating the effect of the grinding angle on the dynamic range change of the SPR resonance valley wavelength and sensitivity, we combined polymer-clad fiber and vitreous-clad fiber by a smart design structure to realize at a single point a two-channel measurement fiber SPR sensor. In this paper, we obtained a beautiful spectral curve from a multi-mode fiber two-channel SPR sensor. In the detection range of the refractive rate between 1.333 RIU and 1.385 RIU, the resonance valley wavelength of channel Ⅰ shifted from 622 nm to 724 nm with a mean average sensitivity of 1961 nm/RIU and the resonance valley wavelength of channel Ⅱ shifted from 741 nm to 976 nm with a mean average sensitivity of 4519 nm/RIU.

SPR 2015. Abstracts

International Nuclear Information System (INIS)

2015-01-01

The volume contains the abstracts of the SPR (society for pediatric radiology) 2015 meeting covering the following issues: fetal imaging, muscoskeletal imaging, cardiac imaging, chest imaging, oncologic imaging, tools for process improvement, child abuse, contrast enhanced ultrasound, image gently - update of radiation dose recording/reporting/monitoring - meaningful or useless meaning?, pediatric thoracic imaging, ALARA.

SPR 2015. Abstracts

Energy Technology Data Exchange (ETDEWEB)

NONE

2015-04-01

The volume contains the abstracts of the SPR (society for pediatric radiology) 2015 meeting covering the following issues: fetal imaging, muscoskeletal imaging, cardiac imaging, chest imaging, oncologic imaging, tools for process improvement, child abuse, contrast enhanced ultrasound, image gently - update of radiation dose recording/reporting/monitoring - meaningful or useless meaning?, pediatric thoracic imaging, ALARA.

Allowable pillar to diameter ratio for strategic petroleum reserve caverns.

Energy Technology Data Exchange (ETDEWEB)

Ehgartner, Brian L.; Park, Byoung Yoon

2011-05-01

This report compiles 3-D finite element analyses performed to evaluate the stability of Strategic Petroleum Reserve (SPR) caverns over multiple leach cycles. When oil is withdrawn from a cavern in salt using freshwater, the cavern enlarges. As a result, the pillar separating caverns in the SPR fields is reduced over time due to usage of the reserve. The enlarged cavern diameters and smaller pillars reduce underground stability. Advances in geomechanics modeling enable the allowable pillar to diameter ratio (P/D) to be defined. Prior to such modeling capabilities, the allowable P/D was established as 1.78 based on some very limited experience in other cavern fields. While appropriate for 1980, the ratio conservatively limits the allowable number of oil drawdowns and hence limits the overall utility and life of the SPR cavern field. Analyses from all four cavern fields are evaluated along with operating experience gained over the past 30 years to define a new P/D for the reserve. A new ratio of 1.0 is recommended. This ratio is applicable only to existing SPR caverns.

77 FR 21846 - Reserve Requirements of Depository Institutions: Reserves Simplification

Science.gov (United States)

2012-04-12

... Requirements of Depository Institutions: Reserves Simplification AGENCY: Board of Governors of the Federal Reserve System. ACTION: Final rule. SUMMARY: The Board is amending Regulation D, Reserve Requirements of Depository Institutions, to simplify the administration of reserve requirements. The final rule creates a...

Floating Chip Mounting System Driven by Repulsive Force of Permanent Magnets for Multiple On-Site SPR Immunoassay Measurements

Science.gov (United States)

Horiuchi, Tsutomu; Tobita, Tatsuya; Miura, Toru; Iwasaki, Yuzuru; Seyama, Michiko; Inoue, Suzuyo; Takahashi, Jun-ichi; Haga, Tsuneyuki; Tamechika, Emi

2012-01-01

We have developed a measurement chip installation/removal mechanism for a surface plasmon resonance (SPR) immunoassay analysis instrument designed for frequent testing, which requires a rapid and easy technique for changing chips. The key components of the mechanism are refractive index matching gel coated on the rear of the SPR chip and a float that presses the chip down. The refractive index matching gel made it possible to optically couple the chip and the prism of the SPR instrument easily via elastic deformation with no air bubbles. The float has an autonomous attitude control function that keeps the chip parallel in relation to the SPR instrument by employing the repulsive force of permanent magnets between the float and a float guide located in the SPR instrument. This function is realized by balancing the upward elastic force of the gel and the downward force of the float, which experiences a leveling force from the float guide. This system makes it possible to start an SPR measurement immediately after chip installation and to remove the chip immediately after the measurement with a simple and easy method that does not require any fine adjustment. Our sensor chip, which we installed using this mounting system, successfully performed an immunoassay measurement on a model antigen (spiked human-IgG) in a model real sample (non-homogenized milk) that included many kinds of interfering foreign substances without any sample pre-treatment. The ease of the chip installation/removal operation and simple measurement procedure are suitable for frequent on-site agricultural, environmental and medical testing. PMID:23202030

77 FR 66361 - Reserve Requirements of Depository Institutions: Reserves Simplification

Science.gov (United States)

2012-11-05

... Requirements of Depository Institutions: Reserves Simplification AGENCY: Board of Governors of the Federal... (Reserve Requirements of Depository Institutions) published in the Federal Register on April 12, 2012. The... simplifications related to the administration of reserve requirements: 1. Create a common two-week maintenance...

Nano Sensing and Energy Conversion Using Surface Plasmon Resonance (SPR

Directory of Open Access Journals (Sweden)

Iltai (Isaac Kim

2015-07-01

Full Text Available Nanophotonic technique has been attracting much attention in applications of nano-bio-chemical sensing and energy conversion of solar energy harvesting and enhanced energy transfer. One approach for nano-bio-chemical sensing is surface plasmon resonance (SPR imaging, which can detect the material properties, such as density, ion concentration, temperature, and effective refractive index in high sensitivity, label-free, and real-time under ambient conditions. Recent study shows that SPR can successfully detect the concentration variation of nanofluids during evaporation-induced self-assembly process. Spoof surface plasmon resonance based on multilayer metallo-dielectric hyperbolic metamaterials demonstrate SPR dispersion control, which can be combined with SPR imaging, to characterize high refractive index materials because of its exotic optical properties. Furthermore, nano-biophotonics could enable innovative energy conversion such as the increase of absorption and emission efficiency and the perfect absorption. Localized SPR using metal nanoparticles show highly enhanced absorption in solar energy harvesting. Three-dimensional hyperbolic metamaterial cavity nanostructure shows enhanced spontaneous emission. Recently ultrathin film perfect absorber is demonstrated with the film thickness is as low as ~1/50th of the operating wavelength using epsilon-near-zero (ENZ phenomena at the wavelength close to SPR. It is expected to provide a breakthrough in sensing and energy conversion applications using the exotic optical properties based on the nanophotonic technique.

Report to the Congress on alternative methods for the Strategic Petroleum Reserve

Energy Technology Data Exchange (ETDEWEB)

1990-02-01

The purpose of this study is to fulfill the requirements of Public Law No. 101-46, approved June 30, 1989. The study describes and evaluates alternative methods for financing the future expansion of the Strategic petroleum Reserve (SPR), both to the current target level of 750 million barrels and to potential future levels of up to one billion barrels.

Pleiotropic Regulation of Virulence Genes in Streptococcus mutans by the Conserved Small Protein SprV.

Science.gov (United States)

Shankar, Manoharan; Hossain, Mohammad S; Biswas, Indranil

2017-04-15

critical for successful disease establishment. Sometimes these regulators, which are potential targets for antimicrobials, are lost in the genomic context due to the lack of annotated homologs. This work outlines the regulatory impact of a small, highly conserved hypothetical protein, SprV, encoded by S. mutans We show that SprV affects the transcript levels of various virulence factors required for normal growth, biofilm formation, stress tolerance, genetic competence, and bacteriocin production. Copyright © 2017 American Society for Microbiology.

SPR imaging combined with cyclic voltammetry for the detection of neural activity

Directory of Open Access Journals (Sweden)

Hui Li

2014-03-01

Full Text Available Surface plasmon resonance (SPR detects changes in refractive index at a metal-dielectric interface. In this study, SPR imaging (SPRi combined with cyclic voltammetry (CV was applied to detect neural activity in isolated bullfrog sciatic nerves. The neural activities induced by chemical and electrical stimulation led to an SPR response, and the activities were recorded in real time. The activities of different parts of the sciatic nerve were recorded and compared. The results demonstrated that SPR imaging combined with CV is a powerful tool for the investigation of neural activity.

Strategic Petroleum Reserve (SPR) additional geologic site characterization studies, Bayou Choctaw salt dome, Louisiana

Energy Technology Data Exchange (ETDEWEB)

Neal, J.T. [Sandia National Labs., Albuquerque, NM (United States); Magorian, T.R. [Magorian (Thomas R.), Amherst, NY (United States); Byrne, K.O.; Denzler, S. [Acres International Corp., Amherst, NY (United States)

1993-09-01

This report revises and updates the geologic site characterization report that was published in 1980. Revised structure maps and sections show interpretative differences in the dome shape and caprock structural contours, especially a major east-west trending shear zone, not mapped in the 1980 report. Excessive gas influx in Caverns 18 and 20 may be associated with this shear zone. Subsidence values at Bayou Choctaw are among the lowest in the SPR system, averaging only about 10 mm/yr but measurement and interpretation issues persist, as observed values often approximate measurement accuracy. Periodic, temporary flooding is a continuing concern because of the low site elevation (less than 10 ft), and this may intensify as future subsidence lowers the surface even further. Cavern 4 was re-sonared in 1992 and the profiles suggest that significant change has not occurred since 1980, thereby reducing the uncertainty of possible overburden collapse -- as occurred at Cavern 7 in 1954. Other potential integrity issues persist, such as the proximity of Cavern 20 to the dome edge, and the narrow web separating Caverns 15 and 17. Injection wells have been used for the disposal of brine but have been only marginally effective thus far; recompletions into more permeable lower Pleistocene gravels may be a practical way of increasing injection capacity and brinefield efficiency. Cavern storage space is limited on this already crowded dome, but 15 MMBBL could be gained by enlarging Cavern 19 and by constructing a new cavern beneath and slightly north of abandoned Cavern 13. Environmental issues center on the low site elevation: the backswamp environment combined with the potential for periodic flooding create conditions that will require continuing surveillance.

Enhanced gas sensing performance of TiO2 functionalized magneto-optical SPR sensors

OpenAIRE

Manera, Maria Grazia; Montagna, G.; Ferreiro-Vila, Elías; González-García, Lola; Sánchez-Valencia, J.R.; González-Elipe, Agustín R.; Cebollada, Alfonso; García-Martín, José Miguel; García-Martín, Antonio; Armelles Reig, Gaspar; Rella, Roberto

2011-01-01

Porous TiO2 thin films deposited by glancing angle deposition are used as sensing layers to monitor their sensing capabilities towards Volatile Organic Compounds both in a standard Surface Plasmon Resonance (SPR) sensor and in Magneto-Optical Surface Plasmon Resonance (MO-SPR) configuration in order to compare their sensing performances. Here our results on the enhanced sensing capability of these TiO2 functionalized MO-SPR sensors with Au/Co/Au transducers with respect to traditional SPR gas...

SPR 2014. Abstracts

Energy Technology Data Exchange (ETDEWEB)

NONE

2014-05-15

The proceedings of the SPR 2014 meeting include abstracts on the following topics: Body imaging techniques: practical advice for clinic work; thoracic imaging: focus on the lungs; gastrointestinal imaging: focus on the pancreas and bowel; genitourinary imaging: focus on gonadal radiology; muscoskeletal imaging; focus on oncology; child abuse and nor child abuse: focus on radiography; impact of NMR and CT imaging on management of CHD; education and communication: art and practice in pediatric radiology.

SPR 2014. Abstracts

International Nuclear Information System (INIS)

2014-01-01

The proceedings of the SPR 2014 meeting include abstracts on the following topics: Body imaging techniques: practical advice for clinic work; thoracic imaging: focus on the lungs; gastrointestinal imaging: focus on the pancreas and bowel; genitourinary imaging: focus on gonadal radiology; muscoskeletal imaging; focus on oncology; child abuse and nor child abuse: focus on radiography; impact of NMR and CT imaging on management of CHD; education and communication: art and practice in pediatric radiology.

Continuity of care of emergency surgical admissions: impact on SpR training.

Science.gov (United States)

Ledwidge, S F C; Bryden, E; Halestrap, P; Galland, R B

2008-06-01

Continuity of patient care is an important component of surgical education. This study assesses continuity of care in the current working climate. Data were collected prospectively on consecutive emergency general surgical admissions during one month. Our SpR rota is a partial shift 24 hour on call with the SpR's own consultant. The SpR is free of commitments the next day following post-take work. The on call general surgery SpR was designated the 'assessor'. Data were analysed according to involvement of the 'assessor' at subsequent stages of the admission--consent, operation, review during admission and review on discharge. Data were also collected defining whether the 'assessor' and operator followed-up the patient. There were 200 admissions; 108 female and 92 male. Overall 23% admissions had the same 'assessor' for all stages of patient care. The 'assessor' dealt with an aspect of patient care in 11% of admissions who underwent an operation and 29% of admissions who were conservatively managed. SpR follow-up of admissions on whom they operated was 70% but only 41% of admissions who were conservatively managed were followed-up by the assessing SpR. Complete in-hospital continuity of care was poor, although SpR follow-up of patients on whom they had operated was better. Introduction of shift patterns has reduced continuity of patient care. This will have a negative impact on both surgical training and patient care.

«[…] en enkel og saklig innføring i norsk språkhistorie» Språkhistorie som norskdidaktisk emne – et faghistorisk utsyn

Directory of Open Access Journals (Sweden)

Stian Hårstad

2016-09-01

Full Text Available Artikkelen tar for seg språkhistorie som norskdidaktisk emne i et faghistorisk perspektiv. På grunnlag av en lang rekke styringsdokumenter (læreplaner og studieplaner og fagdidaktisk og disiplinfaglig litteratur undersøkes hvordan språkets historiske dimensjoner har blitt tematisert som kunnskapsområde. Et hovedfunn i denne gjennomgangen er at det historiske (eller historiserende lengdesnittet har vært til stede gjennom hele 1900-tallet og fortsatt finnes i gjeldende læreplan – om enn med temmelig varierende vektlegging og detaljering. Læreplanene har i stor grad overlatt til praktikerne (lærerne og lærerutdannerne å avgrense hva de språkhistoriske emnene skal romme. Litteraturanalysen viser videre at den didaktiske refleksjonen på dette feltet bare unntaksvis har kommet på trykk, og denne begrensete språkhistorie-didaktiske debatten må forstås på bakgrunn av tilstanden i forsknings- og studiefaget.Nøkkelord: språkhistorie-didaktikk, språkdidaktikk, språkhistorie, norskdidaktikkAbstractThis article deals with language history as a didactic topic in the subject Norwegian as L1. On the basis of a wide range of documents (curricula and syllabi and didactic and disciplinary literature, the article seeks to examine how the historical dimensions of language have been treated as an area of knowledge. A main finding is that the historic (or historicizing perspective has been present through the entire 20th century and still can be found in the current curriculum – though the emphasis and itemization have varied significantly. The curricula have largely entrusted the practicians (the teachers and teacher educators with the powers to delineate the language history topics. The research review further shows that the didactic reflections within this field only sporadically have appeared in print, and this limited didactic discussion of language history must be understood on the background of the condition of the discipline

42 CFR 417.934 - Reserve requirement.

Science.gov (United States)

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Reserve requirement. 417.934 Section 417.934 Public... PLANS Administration of Outstanding Loans and Loan Guarantees § 417.934 Reserve requirement. (a) Timing... section 1305 of the PHS Act was required to establish a restricted reserve account on the earlier of the...

Strategic Petroleum Reserve annual site environmental report for calendar year 1992

International Nuclear Information System (INIS)

1993-06-01

This report, provided annually in accordance with DOE Order 5400.1, summarizes monitoring data collected to assess Strategic Petroleum Reserve (SPR) impacts on the environment. The report serves as a management tool for mitigating such impacts, thus serving the public interest by ensuring environmentally sound operation of the SPR. Included in this report is a description of each site's environment, an overview of the SPR environmental program, and a recapitulation of special environmental activities and events associated with each SPR site during 1992. The active permits and the results of the environmental monitoring program (i.e., air, surface water, ground water, and water discharges) are discussed within each section by site. The quality assurance program is presented which includes results from laboratory and field audits and studies performed internally and by regulatory agencies. In general, no significant adverse environmental impact resulted from any SPR activities during 1992. Environmental areas of concern, such as potential ground water contamination, are fully addressed in the applicable section by site. The SPR continues to maintain an overall excellent environmental record

Strategic Petroleum Reserve, annual site environmental report for calendar year 1991

International Nuclear Information System (INIS)

1992-06-01

This report, provided annually in accordance with DOE Order 5400.1, summarizes monitoring data collected to assess Strategic Petroleum Reserve (SPR) impacts on the environment. The report serves as a management tool for mitigating such impacts, thus serving the public interest by ensuring environmentally sound operation of the SPR. Included in this report is a description of each site's environment, an overview of the SPR environmental program, and a recapitulation of special environmental activities and events associated with each SPR site during 1990. The active permits and the results of the environmental monitoring program (i.e., air, surface vater, groundwater, and water discharges) are discussed within each section by site. The quality assurance program is presented which includes results from laboratory and field audits and studies performed internally and by regulatory agencies. In general, no significant adverse environmental impact resulted from any SPR activities during 1990. Environmental areas of concern, such as potential groundwater contamination, are fully addressed in the applicable section by site. The SPR continues to maintain an overall excellent environmental record

Strategic Petroleum Reserve annual site environmental report for calendar year 1992

Energy Technology Data Exchange (ETDEWEB)

1993-06-01

This report, provided annually in accordance with DOE Order 5400.1, summarizes monitoring data collected to assess Strategic Petroleum Reserve (SPR) impacts on the environment. The report serves as a management tool for mitigating such impacts, thus serving the public interest by ensuring environmentally sound operation of the SPR. Included in this report is a description of each site`s environment, an overview of the SPR environmental program, and a recapitulation of special environmental activities and events associated with each SPR site during 1992. The active permits and the results of the environmental monitoring program (i.e., air, surface water, ground water, and water discharges) are discussed within each section by site. The quality assurance program is presented which includes results from laboratory and field audits and studies performed internally and by regulatory agencies. In general, no significant adverse environmental impact resulted from any SPR activities during 1992. Environmental areas of concern, such as potential ground water contamination, are fully addressed in the applicable section by site. The SPR continues to maintain an overall excellent environmental record.

Reserve requirement systems in OECD countries

OpenAIRE

Yueh-Yun C. O’Brien

2007-01-01

This paper compares the reserve requirements of OECD countries. Reserve requirements are the minimum percentages or amounts of liabilities that depository institutions are required to keep in cash or as deposits with their central banks. To facilitate monetary policy implementation, twenty-four of the thirty OECD countries impose reserve requirements to influence their banking systems’ demand for liquidity. These include twelve OECD countries that are also members of the European Economic and...

12 CFR 204.7 - Supplemental reserve requirement.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Supplemental reserve requirement. 204.7 Section... RESERVE REQUIREMENTS OF DEPOSITORY INSTITUTIONS (REGULATION D) § 204.7 Supplemental reserve requirement... reserve requirement on every depository institution of not more than 4 percent of its total transaction...

Strategic Petroleum Reserve Site Environmental Report for calendar year 1994

International Nuclear Information System (INIS)

1995-01-01

The purpose of this Site Environmental Report (SER) is to characterize site environmental management performance, confirm compliance with environmental standards and requirements, and highlight significant programs and efforts. The SER, provided annually in accordance with Department of Energy DOE Order 5400.1, serves the public by summarizing monitoring data collected to assess how the Strategic Petroleum Reserve (SPR) impacts the environment. This report (SER) provides a balanced synopsis of non-radiological monitoring and regulatory compliance data and affirms that the SPR has been operating within acceptable regulatory limits. Included in this report is a description of each site's environment, an overview of the SPR environmental program, and a recapitulation of special environmental activities and events associated with each SPR site during 1994. Two of these highlights include decommissioning of the Weeks Island facility (disposition of 73 million barrels of crude oil inventory) as well as the degasification of up to 144 million barrels of crude oil inventory at the Bayou Choctaw, Big Hill, Bryan Mound, and West Hackberry facilities. The decision to decommission the Weeks Island facility is a result of diminishing mine integrity from ground water intrusion. Degasifying the crude oil is required to reduce potentially harmful emissions that would occur during oil movements. With regard to still another major environmental action, 43 of the original 84 environmental findings from the 1992 DOE Tiger Team Assessment were closed by the end of 1994. Spills to the environment, another major topic, indicates a positive trend. Total volume of oil spilled in 1994 was only 39 barrels, down from 232 barrels in 1993, and the total volume of brine spilled was only 90 barrels, down from 370 barrels in 1993. The longer term trend for oil and brine spills has declined substantially from 27 in 1990 down to nine in 1994

12 CFR 204.9 - Emergency reserve requirement.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Emergency reserve requirement. 204.9 Section... RESERVE REQUIREMENTS OF DEPOSITORY INSTITUTIONS (REGULATION D) § 204.9 Emergency reserve requirement. (a..., additional reserve requirements on depository institutions at any ratio on any liability upon a finding by at...

Development of surface plasmon resonance (SPR) biosensors for use in the diagnostics of malignant and infectious diseases

Science.gov (United States)

Firdous, S.; Anwar, S.; Rafya, R.

2018-06-01

Surface plasmon resonance (SPR) has become an important optical biosensing technology due to its real-time, label-free, and noninvasive nature. These techniques allow for rapid and ultra-sensitive detection of biological analytes, with applications in medical diagnostics, environmental monitoring, and agriculture. SPR is widely used in the detection of biomolecular interactions, and improvements are required for both sensitivity and in vivo uses for practical applications. In this study, we developed an SPR biosensor to provide a highly sensitive and specific approach to early-stage detection of viral and malignant diseases, such as cancer tumors, for which biomarker detection is very important. A cancer cell line (HeLa cells) with biomarker Rodamine 6G was experimentally analyzed in vitro with our constructed SPR biosensor. It was observed that the biosensor can offer a potentially powerful solution for tumor screening with dominant angular shift. The angular shift for both regents is dominant with a time curve at a wavelength of 632.8 nm of a He–Ne laser. We have successfully captured and detected a biomarker in vitro for cancer diagnostics using the developed instrument.

Functional Conducting Polymers in the Application of SPR Biosensors

Directory of Open Access Journals (Sweden)

Rapiphun Janmanee

2012-01-01

Full Text Available In recent years, conducting polymers have emerged as one of the most promising transducers for both chemical, sensors and biosensors owing to their unique electrical, electrochemical and optical properties that can be used to convert chemical information or biointeractions into electrical or optical signals, which can easily be detected by modern techniques. Different approaches to the application of conducting polymers in chemo- or biosensing applications have been extensively studied. In order to enhance the application of conducting polymers into the area of biosensors, one approach is to introduce functional groups, including carboxylic acid, amine, sulfonate, or thiol groups, into the conducting polymer chain and to form a so-called “self-doped” or by doping with negatively charged polyelectrolytes. The functional conducting polymers have been successfully utilized to immobilize enzymes for construction of biosensors. Recently, the combination of SPR and electrochemical, known as electrochemical-surface plasmon resonance (EC-SPR, spectroscopy, has been used for in situ investigation of optical and electrical properties of conducting polymer films. Moreover, EC-SPR spectroscopy has been applied for monitoring the interaction between biomolecules and electropolymerized conjugated polymer films in biosensor and immunosensor applications. In this paper, recent development and applications on EC-SPR in biosensors will be reviewed.

Observations on vapor pressure in SPR caverns : sources.

Energy Technology Data Exchange (ETDEWEB)

Munson, Darrell Eugene

2010-05-01

The oil of the Strategic Petroleum Reserve (SPR) represents a national response to any potential emergency or intentional restriction of crude oil supply to this country, and conforms to International Agreements to maintain such a reserve. As assurance this reserve oil will be available in a timely manner should a restriction in supply occur, the oil of the reserve must meet certain transportation criteria. The transportation criteria require that the oil does not evolve dangerous gas, either explosive or toxic, while in the process of transport to, or storage at, the destination facility. This requirement can be a challenge because the stored oil can acquire dissolved gases while in the SPR. There have been a series of reports analyzing in exceptional detail the reasons for the increases, or regains, in gas content; however, there remains some uncertainty in these explanations and an inability to predict why the regains occur. Where the regains are prohibitive and exceed the criteria, the oil must undergo degasification, where excess portions of the volatile gas are removed. There are only two known sources of gas regain, one is the salt dome formation itself which may contain gas inclusions from which gas can be released during oil processing or storage, and the second is increases of the gases release by the volatile components of the crude oil itself during storage, especially if the stored oil undergoes heating or is subject to biological generation processes. In this work, the earlier analyses are reexamined and significant alterations in conclusions are proposed. The alterations are based on how the fluid exchanges of brine and oil uptake gas released from domal salt during solutioning, and thereafter, during further exchanges of fluids. Transparency of the brine/oil interface and the transfer of gas across this interface remains an important unanswered question. The contribution from creep induced damage releasing gas from the salt surrounding the cavern is

SPR 2017. Abstracts

Energy Technology Data Exchange (ETDEWEB)

NONE

2017-05-15

The conference proceedings SPR 2017 include abstracts on the following issues: gastrointestinal radiography - inflammatory bowel diseases, cardiovascular CTA, general muscoskeletal radiology, muscoskeletal congenital development diseases, general pediatric radiology - chest, muscoskeletal imaging - marrow and infectious disorders, state-of-the-art body MR imaging, practical pediatric sonography, quality and professionalism, CT imaging in congenital heart diseases, radiographic courses, body MT techniques, contrast enhanced ultrasound, machine learning, forensic imaging, the radiation dos conundrum - reconciling imaging, imagining and managing, the practice of radiology, interventional radiology, neuroradiology, PET/MR.

7 CFR 981.51 - Requirements for reserve.

Science.gov (United States)

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Requirements for reserve. 981.51 Section 981.51... Regulating Handling Volume Regulation § 981.51 Requirements for reserve. Each handler may satisfy his reserve... include grade requirements for reserve almonds delivered to human consumption outlets. [41 FR 26853, June...

12 CFR 204.4 - Computation of required reserves.

Science.gov (United States)

2010-01-01

... RESERVE REQUIREMENTS OF DEPOSITORY INSTITUTIONS (REGULATION D) § 204.4 Computation of required reserves. (a) In determining the reserve requirement under this part, the amount of cash items in process of... reserves are computed by applying the reserve requirement ratios below to net transaction accounts...

The Strategic Petroleum Reserve: United States energy security, oil politics, and petroleum reserves policies in the twentieth century

Science.gov (United States)

Beaubouef, Bruce Andre

The history of U.S. petroleum reserves policies in the twentieth century, including the Strategic Petroleum Reserve (SPR) program, provides a case study of the economic and political aspects of national security, and shows the ways in which the American political economy influences national security. One key problem plagued federal petroleum reserve programs and proposals throughout the twentieth century. In a political economy which traditionally placed strong emphasis upon the sanctity of private property and free markets, could the government develop an emergency petroleum reserve policy despite opposition from the private sector? Previous literature on the SPR and oil-stockpiling programs has largely disregarded the historical perspective, focusing instead upon econometric models, suggesting future oil-stockpiling policy options. This study will also make conclusions about the future of governmental oil-stockpiling policies, particularly with regard to the SPR program, but it will do so informed by a systematic history of the emergency petroleum reserve impulse in the twentieth century. Through a study of the emergency petroleum reserve impulse, one can see how the American political economy of oil and energy changed over the twentieth century. As petroleum became crucial to the military and then economic security of the United States, the federal government sought to develop emergency petroleum reserves first for the military, then for the civilian economy. But while the American petroleum industry could deliver the energy "goods" to American energy consumers at a reasonable price, the companies reigned supreme in the political equation. While that was true, federal petroleum reserve programs and proposals conflicted with and were overwhelmed by the historic American tradition of individual economic and private property rights. The depletion of American petroleum reserves changed that political equation, and the ensuing energy crises of the 1970s not only

UV-SPR biosensor for biomolecular interaction studies

Science.gov (United States)

Geiss, F. A.; Fossati, S.; Khan, I.; Gisbert Quilis, N.; Knoll, W.; Dostalek, J.

2017-05-01

UV surface plasmon resonance (SPR) for direct in situ detection of protein binding events is reported. A crossed relief aluminum grating was employed for diffraction coupling to surface plasmons as an alternative to more commonly used attenuated total reflection method. Wavelength interrogation of SPR was carried out by using transmission measurements in order to probe odorant-binding protein 14 (OBP14) of the honey bee (Apis mellifera). The native oxide layer on the top of an aluminum grating sensor chip allows for covalent coupling of protein molecules by using regular silane-based linkers. The probing of bound OBP14 protein at UV with confined field of surface plasmons holds potential for further studies of interaction with recently developed artificial fluorescent odorants.

Molecular self assembly of mixed comb-like dextran surfactant polymers for SPR virus detection.

Science.gov (United States)

Mai-Ngam, Katanchalee; Kiatpathomchai, Wansika; Arunrut, Narong; Sansatsadeekul, Jitlada

2014-11-04

The synthesis of two comb-like dextran surfactant polymers, that are different in their dextran molecular weight (MW) distribution and the presence of carboxylic groups, and their characterization are reported. A bimodal carboxylic dextran surfactant polymer consists of poly(vinyl amine) (PVAm) backbone with carboxyl higher MW dextran, non-functionalized lower MW dextran and hydrophobic hexyl branches; while a monomodal dextran surfactant polymer is PVAm grafted with non-functionalized lower MW dextran and hexyl branches. Layer formation of non-covalently attached dextran chains with bimodal MW distributions on a surface plasmon resonance (SPR) chip was investigated from the perspective of mixed physisorption of the bimodal and monomodal surfactant polymers. Separation distances between the carboxylic longer dextran side chains within the bimodal surfactant polymer and between the whole bimodal surfactant molecules on the chip surface could be well-controlled. SPR analysis of shrimp yellow head virus using our mixed surfactant chips showed dependence on synergetic adjustment of these separation distances. Copyright © 2014 Elsevier Ltd. All rights reserved.

Recent operational history of the new Sandia Pulsed Reactor III (SPR III)

International Nuclear Information System (INIS)

Schmidt, T.R.; Estes, B.F.; Reuscher, J.A.

1977-01-01

The Sandia Pulsed Reactor III (SPR III) is a fast-pulse research reactor which was designed and built at Sandia Laboratories and achieved criticality in August 1975. The reactor is now characterized and is in an operational configuration. The core consists of 18 fuel plates (258 kg fuel mass) of fully enriched uranium alloyed with 10 wt.% molybdenum. It is arranged in an annular configuration with an inside diameter of 17.78 cm, an outside diameter of 29.72 cm, and a height of 35.9 cm. The reactor core uses reflectors of copper and aluminum for control and an external bolting arrangement to secure the fuel plates. SPR III and SPR II are operated on an interchangeable basis using the same facility and control system. As of June 1977, SPR III has had over 240 operations with core temperatures up to 541 0 C

10 CFR 1049.8 - Training of SPR Protective Force Officers and qualification to carry firearms.

Science.gov (United States)

2010-01-01

... sufficient to maintain at least the minimum level of competency required for the successful performance of... competence to perform tasks associated with their responsibilities. The basic course shall include the...) Operating in such a manner as to preserve SPR sites and facilities; (9) Communications, including methods...

A model based on stochastic dynamic programming for determining China's optimal strategic petroleum reserve policy

International Nuclear Information System (INIS)

Zhang Xiaobing; Fan Ying; Wei Yiming

2009-01-01

China's Strategic Petroleum Reserve (SPR) is currently being prepared. But how large the optimal stockpile size for China should be, what the best acquisition strategies are, how to release the reserve if a disruption occurs, and other related issues still need to be studied in detail. In this paper, we develop a stochastic dynamic programming model based on a total potential cost function of establishing SPRs to evaluate the optimal SPR policy for China. Using this model, empirical results are presented for the optimal size of China's SPR and the best acquisition and drawdown strategies for a few specific cases. The results show that with comprehensive consideration, the optimal SPR size for China is around 320 million barrels. This size is equivalent to about 90 days of net oil import amount in 2006 and should be reached in the year 2017, three years earlier than the national goal, which implies that the need for China to fill the SPR is probably more pressing; the best stockpile release action in a disruption is related to the disruption levels and expected continuation probabilities. The information provided by the results will be useful for decision makers.

Historical Cavern Floor Rise for All SPR Sites

Energy Technology Data Exchange (ETDEWEB)

Moriarty, Dylan Michael [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2016-09-01

The Strategic Petroleum Reserve (SPR) contains the largest supply is the largest stockpile of government-owned emergency crude oil in the world. The oil is stored in multiple salt caverns spread over four sites in Louisiana and Texas. Cavern infrastructure near the bottom of the cavern can be damaged from vertical floor movement. This report presents a comprehensive history of floor movements in each cavern. Most of the cavern floor rise rates ranged from 0.5-3.5 ft/yr, however, there were several caverns with much higher rise rates. BH103, BM106, and BH105 had the three highest rise rates. Information from this report will be used to better predict future vertical floor movements and optimally place cavern infrastructure. The reasons for floor rise are not entirely understood and should be investigated.

Comparison of different photoresist buffer layers in SPR sensors based on D-shaped POF and gold film

Science.gov (United States)

Cennamo, Nunzio; Pesavento, Maria; De Maria, Letizia; Galatus, Ramona; Mattiello, Francesco; Zeni, Luigi

2017-04-01

A comparative analysis of two optical fiber sensing platforms is presented. The sensors are based on surface plasmon resonance (SPR) in a D-shaped plastic optical fiber (POF) with a photoresist buffer layer between the exposed POF core and the thin gold film. We show how the sensor's performances change when the photoresist layer changes. The photoresist layers proposed in this analysis are SU-8 3005 and S1813. The experimental results are congruent with the numerical studies and it is instrumental for chemical and bio-chemical applications. Usually, the photoresist layer is required in order to increase the performance of the SPR-POF sensor.

76 FR 68064 - Reserve Requirements of Depository Institutions

Science.gov (United States)

2011-11-03

... Reserve Requirements of Depository Institutions AGENCY: Board of Governors of the Federal Reserve System. ACTION: Final rule. SUMMARY: The Board is amending Regulation D, Reserve Requirements of Depository Institutions, to reflect the annual indexing of the reserve requirement exemption amount and the low reserve...

Reserve Requirements and Monetary Management; An Introduction

OpenAIRE

International Monetary Fund

1993-01-01

Reserve requirements are widely used by central banks as a means to improve monetary control, an instrument for policy implementation, a source of revenue, and a safeguard of bank liquidity. The effectiveness of reserve requirements in fulfilling these functions is reviewed, and the detailed modalities of their use are examined. Reserve requirements in a sample of developing countries are described.

47 CFR 10.540 - Attestation requirement. [Reserved

Science.gov (United States)

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Attestation requirement. [Reserved] 10.540 Section 10.540 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM Equipment Requirements § 10.540 Attestation requirement. [Reserved] ...

Surface Plasmon Resonance (SPR Phenomenon of the Oxidizing and Reducing Polypyrrole

Directory of Open Access Journals (Sweden)

Nurlaila Rajabiah

2016-12-01

Full Text Available Surface Plasmon Resonance (SPR phenomenon of the oxidizing and reducing polypyrrole (PPy have been observed using a modified Au/PPy Kretschmann configuration. The observation was carried out through simulation Winspall 3.02 software and compared with some experimental data refractive index (n, absorbance index (, and thickness (τ reported in other literatures with spectroscopy ellipsometry. This simulation assumed that the SPR system use BK-7 halfcylinder prism (n= 1,515 and the laser beam was generated by HeNe (λ= 632,8 nm. The result showed that the optimum layer thickness of polypyrrole with neutral electrolyte solution in the reduction state is of about 20 nm. The polypyrrole with an acid solution in the oxidation state showed that the reflectivity curve is sharper and the width of the curve is smaller than the neutral electrolyte solution in the reduction state with the SPR angle of about 46,810 and the reflectivity value of about 0,217. Polypyrrole in a state of oxidation and reduction, related to the absorption, film thickness, and dielectric constant of materials, affected to the SPR angle shift and dip curve

75 FR 65563 - Reserve Requirements of Depository Institutions

Science.gov (United States)

2010-10-26

... Requirements of Depository Institutions AGENCY: Board of Governors of the Federal Reserve System. ACTION: Final rule. SUMMARY: The Board is amending Regulation D, Reserve Requirements of Depository Institutions, to reflect the annual indexing of the reserve requirement exemption amount and the low reserve tranche for...

78 FR 66249 - Reserve Requirements of Depository Institutions

Science.gov (United States)

2013-11-05

... Requirements of Depository Institutions AGENCY: Board of Governors of the Federal Reserve System. ACTION: Final rule. SUMMARY: The Board is amending Regulation D, Reserve Requirements of Depository Institutions, to reflect the annual indexing of the reserve requirement exemption amount and the low reserve tranche for...

77 FR 65773 - Reserve Requirements of Depository Institutions

Science.gov (United States)

2012-10-31

... Requirements of Depository Institutions AGENCY: Board of Governors of the Federal Reserve System. ACTION: Final rule. SUMMARY: The Board is amending Regulation D, Reserve Requirements of Depository Institutions, to reflect the annual indexing of the reserve requirement exemption amount and the low reserve tranche for...

SPR based immunosensor for detection of Legionella pneumophila in water samples

Science.gov (United States)

Enrico, De Lorenzis; Manera, Maria G.; Montagna, Giovanni; Cimaglia, Fabio; Chiesa, Maurizio; Poltronieri, Palmiro; Santino, Angelo; Rella, Roberto

2013-05-01

Detection of legionellae by water sampling is an important factor in epidemiological investigations of Legionnaires' disease and its prevention. To avoid labor-intensive problems with conventional methods, an alternative, highly sensitive and simple method is proposed for detecting L. pneumophila in aqueous samples. A compact Surface Plasmon Resonance (SPR) instrumentation prototype, provided with proper microfluidics tools, is built. The developed immunosensor is capable of dynamically following the binding between antigens and the corresponding antibody molecules immobilized on the SPR sensor surface. A proper immobilization strategy is used in this work that makes use of an important efficient step aimed at the orientation of antibodies onto the sensor surface. The feasibility of the integration of SPR-based biosensing setups with microfluidic technologies, resulting in a low-cost and portable biosensor is demonstrated.

Label-free SPR detection of gluten peptides in urine for non-invasive celiac disease follow-up.

Science.gov (United States)

Soler, Maria; Estevez, M-Carmen; Moreno, Maria de Lourdes; Cebolla, Angel; Lechuga, Laura M

2016-05-15

Motivated by the necessity of new and efficient methods for dietary gluten control of celiac patients, we have developed a simple and highly sensitive SPR biosensor for the detection of gluten peptides in urine. The sensing methodology enables rapid and label-free quantification of the gluten immunogenic peptides (GIP) by using G12 mAb. The overall performance of the biosensor has been in-depth optimized and evaluated in terms of sensitivity, selectivity and reproducibility, reaching a limit of detection of 0.33 ng mL(-1). Besides, the robustness and stability of the methodology permit the continuous use of the biosensor for more than 100 cycles with excellent repeatability. Special efforts have been focused on preventing and minimizing possible interferences coming from urine matrix enabling a direct analysis in this fluid without requiring extraction or purification procedures. Our SPR biosensor has proven to detect and identify gluten consumption by evaluating urine samples from healthy and celiac individuals with different dietary gluten conditions. This novel biosensor methodology represents a novel approach to quantify the digested gluten peptides in human urine with outstanding sensitivity in a rapid and non-invasive manner. Our technique should be considered as a promising opportunity to develop Point-of-Care (POC) devices for an efficient, simple and accurate gluten free diet (GFD) monitoring as well as therapy follow-up of celiac disease patients. Copyright © 2015 Elsevier B.V. All rights reserved.

12 CFR 615.5134 - Liquidity reserve requirement.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Liquidity reserve requirement. 615.5134 Section..., LOAN POLICIES AND OPERATIONS, AND FUNDING OPERATIONS Investment Management § 615.5134 Liquidity reserve requirement. (a) Each Farm Credit bank must maintain a liquidity reserve, discounted in accordance with...

A public finance analysis of multiple reserve requirements

OpenAIRE

Espinosa-Vega, Marco; Russell, Steven

1998-01-01

This paper analyzes multiple reserve requirements of the type that have been imposed by a number of developing countries. We show that previous theoretical work on this topic has not succeeded in providing a social welfare rationale for the existence of multiple reserve requirements: in the basic reserve requirements model, any allocation that can be supported by a multiple-reserves regime can also be supported by a single-bond reserve requirement. We go on to present extended versions of the...

40 CFR 410.02 - Monitoring requirements. [Reserved

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Monitoring requirements. [Reserved] 410.02 Section 410.02 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT... requirements. [Reserved] ...

40 CFR 429.12 - Monitoring requirements. [Reserved

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Monitoring requirements. [Reserved] 429.12 Section 429.12 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT... Monitoring requirements. [Reserved] ...

Dehumidification effects in the superheated region (SPR) of a direct expansion (DX) air cooling coil

International Nuclear Information System (INIS)

Xia Liang; Chan Mingyin; Deng Shiming; Xu Xiangguo

2009-01-01

A DX air cooling coil may normally be assumed to have two regions in its refrigerant side, according to refrigerant status, a two-phase region (TPR) and a superheated region (SPR). Dry air side surface of the SPR in a DX air cooling coil has been normally assumed in lumped-parameter mathematical models previously developed without however being validated. Therefore, an experimental study has been carried out to examine such an assumption under different operating conditions. The experimental results suggested that the air side surface of the SPR in a DX air cooling coil was either fully or partially wet under all experimental conditions and assuming dry air side of the SPR could lead to an underestimated total amount of water vapor condensed on the entire DX coil surface. Therefore, it is recommended that the assumption of dry air side in a SPR be no longer used in future lumped-parameter models to be developed for improved modeling accuracy.

Enhancement in sensitivity of graphene-based zinc oxide assisted bimetallic surface plasmon resonance (SPR) biosensor

Science.gov (United States)

Kumar, Rajeev; Kushwaha, Angad S.; Srivastava, Monika; Mishra, H.; Srivastava, S. K.

2018-03-01

In the present communication, a highly sensitive surface plasmon resonance (SPR) biosensor with Kretschmann configuration having alternate layers, prism/zinc oxide/silver/gold/graphene/biomolecules (ss-DNA) is presented. The optimization of the proposed configuration has been accomplished by keeping the constant thickness of zinc oxide (32 nm), silver (32 nm), graphene (0.34 nm) layer and biomolecules (100 nm) for different values of gold layer thickness (1, 3 and 5 nm). The sensitivity of the proposed SPR biosensor has been demonstrated for a number of design parameters such as gold layer thickness, number of graphene layer, refractive index of biomolecules and the thickness of biomolecules layer. SPR biosensor with optimized geometry has greater sensitivity (66 deg/RIU) than the conventional (52 deg/RIU) as well as other graphene-based (53.2 deg/RIU) SPR biosensor. The effect of zinc oxide layer thickness on the sensitivity of SPR biosensor has also been analysed. From the analysis, it is found that the sensitivity increases significantly by increasing the thickness of zinc oxide layer. It means zinc oxide intermediate layer plays an important role to improve the sensitivity of the biosensor. The sensitivity of SPR biosensor also increases by increasing the number of graphene layer (upto nine layer).

20 CFR 617.60 - Administration requirements. [Reserved

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Administration requirements. [Reserved] 617.60 Section 617.60 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR... Agencies § 617.60 Administration requirements. [Reserved] ...

Optimization of SPR signals: Monitoring the physical structures and refractive indices of prisms

Science.gov (United States)

Maisarah Mukhtar, Wan; Halim, Razman Mohd; Hassan, Hazirah

2017-11-01

Surface plasmon resonance (SPR) can only be achieved if sufficient energy is provided at the boundary between metal and dielectric. An employment of prism as a light coupler by using Kretschmann configuration is one of the alternative for the production of adequate energy to be generated as surface plasmon polaritons (SPP). This work is carried out to investigate the effect of physical structure of the prism and its refractive index to the excitation of SPPs. A 50nm gold thin metal film with dielectric constant of ɛ=-12.45i+1.3 was deposited on the hypotenuse surface of the prisms. The physical structures of the prisms were varied such as triangular, conical, hemispherical and half cylindrical. These prisms were classified into two types of refractive indices (RI), namely n=1.51(type BK7) and n=1.77(type SF11). Based on SPR curve analyses, we discovered that strong SPR signals which consist of 82.98% photons were excited as SPPs can be obtained by using type-BK7 prism with physical structures of hemispherical or half cylindrical. From the view of selectivity ability as sensors, the usage of type-SF11 prisms (half cylindrical and hemispherical) able to enhance this impressive feature in which sharp SPR curves with small FWHM values were obtained. In conclusion, apart from properties of thin film materials, the physical structure of prisms and their RI values play crucial roles to obtain optimum SPR signal. High sensitivity SPR sensor can be established with the appointment of type-BK7 prisms (hemispherical or half cylindrical shape) as light couplers.

Optimization of SPR signals: Monitoring the physical structures and refractive indices of prisms

Directory of Open Access Journals (Sweden)

Mukhtar Wan Maisarah

2017-01-01

Full Text Available Surface plasmon resonance (SPR can only be achieved if sufficient energy is provided at the boundary between metal and dielectric. An employment of prism as a light coupler by using Kretschmann configuration is one of the alternative for the production of adequate energy to be generated as surface plasmon polaritons (SPP. This work is carried out to investigate the effect of physical structure of the prism and its refractive index to the excitation of SPPs. A 50nm gold thin metal film with dielectric constant of ɛ=-12.45i+1.3 was deposited on the hypotenuse surface of the prisms. The physical structures of the prisms were varied such as triangular, conical, hemispherical and half cylindrical. These prisms were classified into two types of refractive indices (RI, namely n=1.51(type BK7 and n=1.77(type SF11. Based on SPR curve analyses, we discovered that strong SPR signals which consist of 82.98% photons were excited as SPPs can be obtained by using type-BK7 prism with physical structures of hemispherical or half cylindrical. From the view of selectivity ability as sensors, the usage of type-SF11 prisms (half cylindrical and hemispherical able to enhance this impressive feature in which sharp SPR curves with small FWHM values were obtained. In conclusion, apart from properties of thin film materials, the physical structure of prisms and their RI values play crucial roles to obtain optimum SPR signal. High sensitivity SPR sensor can be established with the appointment of type-BK7 prisms (hemispherical or half cylindrical shape as light couplers.

Språkpolitikk og (usynleggjering i det semiotiske landskapet på Universitetet i Tromsø

Directory of Open Access Journals (Sweden)

Åse Mette Johansen

2013-01-01

Full Text Available I denne artikkelen analyserer vi det semiotiske landskapet som famnar om og er ein del av staden Universitetet i Tromsø (UiT, inkludert Universitetssykehuset Nord-Norge (UNN. Analysen bygger på eit todelt datamateriale som om­fattar fotografi frå universitets­området i tillegg til relevante dokument om språk­lovgjeving og andre offisielle vedtak om språkbruk. Dei aktuelle språka er norsk (bokmål og nynorsk, nord­samisk, engelsk og kvensk/finsk. I tillegg blir ymse slag visuelle symbol under­kasta analyse. Også kunstnarleg utsmykking blir kort omtala. Vi viser korleis synleggjering av ulike språk på UiT er eit resultat av språkpolitikk på ulike nivå, men også er påverka av meir implisitte faktorar som lokale og nasjonale språkhierarki og, ikkje minst, konstruksjonen av ein regional institusjons­identitet som blir uttrykt gjennom det semiotiske landskapet meir generelt. Som ramme rundt denne analysen gjer vi dessutan ein ekskurs til det som i 2011 utløyste ein intens debatt i Tromsø kommune, nemleg spørsmålet om kommunen burde eller ikkje burde bli innlemma i forvaltningsområdet for samisk språk. Den måten denne problemstillinga er blitt takla på av politiske organ i kommunen, og ikkje minst debatten om den i medieoffentlegheita, står i skarp kontrast til den fleirspråklege freden som omgjev universitetet og universitets­sjukehuset.

Experimental results for characterization of a tapered plastic optical fiber sensor based on SPR

Science.gov (United States)

Cennamo, N.; Galatus, R.; Zeni, L.

2015-05-01

The experimental results obtained with two different Plastic Optical Fiber (POF) geometries, tapered and not-tapered, for a sensor based on Surface Plasmon Resonance (SPR) are presented. SPR is used for determining the refractive index variations at the interface between a gold layer and a dielectric medium (aqueous medium). In this work SPR sensors in POF configurations, useful for bio-sensing applications, have been realized for the optimization of the sensitivity and experimentally tested. The results show as the sensitivity increases with the tapered POF configuration, when the refractive index of aqueous medium increases.

Development of a β-Lactoglobulin Sensor Based on SPR for Milk Allergens Detection

Directory of Open Access Journals (Sweden)

Jon Ashley

2018-03-01

Full Text Available A sensitive and label-free surface plasmon resonance (SPR based sensor was developed in this work for the detection of milk allergens. β-lactoglobulin (BLG protein was used as the biomarker for cow milk detection. This is to be used directly in final rinse samples of cleaning in-place (CIP systems of food manufacturers. The affinity assay was optimised and characterised before a standard curve was performed in pure buffer conditions, giving a detection limit of 0.164 µg mL−1 as a direct binding assay. The detection limit can be further enhanced through the use of a sandwich assay and amplification with nanomaterials. However, this was not required here, as the detection limit achieved exceeded the required allergen detection levels of 2 µg mL−1 for β-lactoglobulin. The binding affinities of the polyclonal antibody for BLG, expressed by the dissociation constant (KD, were equal to 2.59 × 10−9 M. The developed SPR-based sensor offers several advantages in terms of label-free detection, real-time measurements, potential on-line system and superior sensitivity when compared to ELISA-based techniques. The method is novel for this application and could be applied to wider food allergen risk management decision(s in food manufacturing.

Effekten af sprøjtemiddelafdrift på buske og træer i læhegn

DEFF Research Database (Denmark)

Kjær, C.; Strandberg, M. T.; Erlandsen, M.

Forsøg med sprøjtning af tjørn med ukrudtsmidlet metsul-furon-methyl har vist effekter både i samme år som sprøjtning og året efter. Sprøjtemidlet, som anvendes til bekæmpelse af bredbladet ukrudt i kornmarker, kan formentlig ved afdrift til markomgivelser som hegn og skovkanter medføre en længer...

24 CFR 266.110 - Reserve requirements.

Science.gov (United States)

2010-04-01

... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Housing Finance Agency Requirements § 266.110 Reserve requirements. (a) HFAs with top-tier designation or overall...

Required reserves as a credit policy tool

OpenAIRE

Mimir, Yasin; Sunel, Enes; Taskin, Temel

2012-01-01

This paper conducts a quantitative investigation of the role of reserve requirements as a macroprudential policy tool. We build a monetary DSGE model with a banking sector in which (i) an agency problem between households and banks leads to endogenous capital constraints for banks in obtaining funds from households, (ii) banks are subject to time-varying reserve requirements that countercyclically respond to expected credit growth, (iii) households face cash-in-advance constraints, requiring ...

Combinations of SPR and MS for Characterizations of Native and Recombinant Proteins in Cell Lysates

DEFF Research Database (Denmark)

Borch, Jonas; Roepstorff, Peter

2006-01-01

Surface plasmon resonance and mass spectrometry (SPR-MS) has been combined for quality check of recombinant 6xHis-tagged 14-3-3 proteins expressed in Escherichia coli. Lysates were injected over an SPR sensorchip with immobilized Ni2+ for SPR analysis of the specific Ni2+ binding response...... and stability. To validate the identity, intactness and homogeneity of the captured proteins were eluted for mass spectrometric analysis of intact molecular weight and peptide mass mapping. Additionally, the captured recombinant proteins were investigated for specific binding to known phosphorylated ligands...... of 14-3-3 proteins in order to test their activity. Specific binding of recombinant and native 14-3-3 proteins in complex mixtures to immobilized phosphopeptides and subsequent elution was also tested by SPR-MS. Ammonium sulfate precipitate fractions from lysates of E. coli expressing 14-3-3 protein...

Správa nemovitosti versus facility management

OpenAIRE

Rázga, Štěpán

2008-01-01

Problematiku facility managementu a správy nemovitostí práce uceleně shrnuje a porovnává teoretické předpoklady a metodické postupy plynoucí z výuky facility managementu na VŠE v Praze s výkonem daných činností v praxi.

12 CFR 652.20 - Liquidity reserve management and requirements.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Liquidity reserve management and requirements... AGRICULTURAL MORTGAGE CORPORATION FUNDING AND FISCAL AFFAIRS Investment Management § 652.20 Liquidity reserve management and requirements. (a) Minimum liquidity reserve requirement. Within 24 months of this rule...

24 CFR 884.225 - PHA reporting requirements. [Reserved

Science.gov (United States)

2010-04-01

... reporting requirements. [Reserved] ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false PHA reporting requirements. [Reserved] 884.225 Section 884.225 Housing and Urban Development Regulations Relating to Housing and Urban...

Enhanced magneto-optical SPR platform for amine sensing based on Zn porphyrin dimers

OpenAIRE

Manera, M. G.; Ferreiro-Vila, E.; Garcia-Martin, J. M.; Cebollada, A.; Garcia-Martin, A.; Giancane, G.; Valli, L.; Rella, R.

2013-01-01

Ethane-bridged Zn porphyrins dimers (ZnPP) have been deposited by Langmuir-Schäfer (LS) deposition technique onto proper transducer layers for surface plasmon resonance (SPR) and magneto-optical surface plasmon resonance (MO-SPR) characterization techniques performed in controlled atmosphere. This last tool has emerged as a novel and very performing sensing technique using as transducer layers a combination of noble and magnetic layers deposited onto glass substrates. A magnetic actuation all...

Report to Congress on the feasibility of establishing a heating oil component to the Strategic Petroleum Reserve. Volume 1

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-06-01

In the Autumn of 1996, consumers and Members of Congress from the Northeast expressed concern about high prices for heating oil and historically low levels of inventories. Some Members of Congress advocated building a Federal inventory of heating oil as part of the Strategic Petroleum Reserve (SPR). Regional reserves are authorized as part of the SPR for import dependent regions by the Energy Policy and Conservation Act. In response, the Department of Energy (DOE) proposed a series of studies related to heating fuels, including a study of the desirability, feasibility, and cost of creating a Federal reserve containing distillate fuel. This report documents that study.

Gold nanoparticle-enhanced multiplexed imaging surface plasmon resonance (iSPR) detection of Fusarium mycotoxins in wheat

Science.gov (United States)

A rapid, sensitive and multiplexed imaging surface plasmon resonance (iSPR) biosensor assay was developed and validated for three Fusarium toxins, deoxynivalenol (DON), zearalenone (ZEA) and T-2 toxin. The iSPR assay was based on a competitive inhibition format with secondary antibodies (Ab2) conjug...

Effect of sulfasalazine on human neuroblastoma: analysis of sepiapterin reductase (SPR) as a new therapeutic target

International Nuclear Information System (INIS)

Yco, Lisette P.; Geerts, Dirk; Mocz, Gabor; Koster, Jan; Bachmann, André S.

2015-01-01

Neuroblastoma (NB) is an aggressive childhood malignancy in children up to 5 years of age. High-stage tumors frequently relapse even after aggressive multimodal treatment, and then show therapy resistance, typically resulting in patient death. New molecular-targeted compounds that effectively suppress tumor growth and prevent relapse with more efficacy are urgently needed. We and others previously showed that polyamines (PA) like spermidine and spermine are essential for NB tumorigenesis and that DFMO, an inhibitor of the key PA synthesis gene product ODC, is effective both in vitro and in vivo, securing its evaluation in NB clinical trials. To find additional compounds interfering with PA biosynthesis, we tested sulfasalazine (SSZ), an FDA-approved salicylate-based anti-inflammatory and immune-modulatory drug, recently identified to inhibit sepiapterin reductase (SPR). We earlier presented evidence for a physical interaction between ODC and SPR and we showed that RNAi-mediated knockdown of SPR expression significantly reduced native ODC enzyme activity and impeded NB cell proliferation. Human NB mRNA expression datasets in the public domain were analyzed using the R2 platform. Cell viability, isobologram, and combination index analyses as a result of SSZ treatment with our without DFMO were carried out in NB cell cultures. Molecular protein-ligand docking was achieved using the GRAMM algorithm. Statistical analyses were performed with the Kruskal-Wallis test, 2log Pearson test, and Student’s t test. In this study, we show the clinical relevance of SPR in human NB tumors. We found that high SPR expression is significantly correlated to unfavorable NB characteristics like high age at diagnosis, MYCN amplification, and high INSS stage. SSZ inhibits the growth of NB cells in vitro, presumably due to the inhibition of SPR as predicted by computational docking of SSZ into SPR. Importantly, the combination of SSZ with DFMO produces synergistic antiproliferative effects

Effect of sulfasalazine on human neuroblastoma: analysis of sepiapterin reductase (SPR) as a new therapeutic target.

Science.gov (United States)

Yco, Lisette P; Geerts, Dirk; Mocz, Gabor; Koster, Jan; Bachmann, André S

2015-06-21

Neuroblastoma (NB) is an aggressive childhood malignancy in children up to 5 years of age. High-stage tumors frequently relapse even after aggressive multimodal treatment, and then show therapy resistance, typically resulting in patient death. New molecular-targeted compounds that effectively suppress tumor growth and prevent relapse with more efficacy are urgently needed. We and others previously showed that polyamines (PA) like spermidine and spermine are essential for NB tumorigenesis and that DFMO, an inhibitor of the key PA synthesis gene product ODC, is effective both in vitro and in vivo, securing its evaluation in NB clinical trials. To find additional compounds interfering with PA biosynthesis, we tested sulfasalazine (SSZ), an FDA-approved salicylate-based anti-inflammatory and immune-modulatory drug, recently identified to inhibit sepiapterin reductase (SPR). We earlier presented evidence for a physical interaction between ODC and SPR and we showed that RNAi-mediated knockdown of SPR expression significantly reduced native ODC enzyme activity and impeded NB cell proliferation. Human NB mRNA expression datasets in the public domain were analyzed using the R2 platform. Cell viability, isobologram, and combination index analyses as a result of SSZ treatment with our without DFMO were carried out in NB cell cultures. Molecular protein-ligand docking was achieved using the GRAMM algorithm. Statistical analyses were performed with the Kruskal-Wallis test, 2log Pearson test, and Student's t test. In this study, we show the clinical relevance of SPR in human NB tumors. We found that high SPR expression is significantly correlated to unfavorable NB characteristics like high age at diagnosis, MYCN amplification, and high INSS stage. SSZ inhibits the growth of NB cells in vitro, presumably due to the inhibition of SPR as predicted by computational docking of SSZ into SPR. Importantly, the combination of SSZ with DFMO produces synergistic antiproliferative effects

Surface functionalization of SPR chip for specific molecular interaction analysis under flow condition

Directory of Open Access Journals (Sweden)

Tao Ma

2017-03-01

Full Text Available Surface functionalization of sensor chip for probe immobilization is crucial for the biosensing applications of surface plasmon resonance (SPR sensors. In this paper, we report a method circulating the dopamine aqueous solution to coat polydopamine film on sensing surface for surface functionalization of SPR chip. The polydopamine film with available thickness can be easily prepared by controlling the circulation time and the biorecognition elements can be immobilized on the polydopamine film for specific molecular interaction analysis. These operations are all performed under flow condition in the fluidic system, and have the advantages of easy implementation, less time consuming, and low cost, because the reagents and devices used in the operations are routinely applied in most laboratories. In this study, the specific absorption between the protein A probe immobilized on the sensing surface and human immunoglobulin G in the buffer is monitored based on this surface functionalization strategy to demonstrated its feasibility for SPR biosensing applications.

Heating of aluminum by SPR-III burst

International Nuclear Information System (INIS)

Judd, S.V.

1987-01-01

Real time temperature measurements were made on an aluminum cylinder exposed to radiation bursts at SPR-III at neutron levels from 10 11 cm -2 to 4.5 x 10 14 cm -2 . Precision thermistors and high speed A/D converters were used to measure temperature with .0025 degree C resolution at 20ms intervals following the burst. Temperature data is presented as a function of neutron fluence

Environmental Survey preliminary report, Strategic Petroleum Reserve, Texas and Louisiana Gulf Coast

Energy Technology Data Exchange (ETDEWEB)

1989-01-01

This report presents the preliminary environmental findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Strategic Petroleum Reserve (SPR), located in Louisiana and Texas, and conducted in two segments from November 30 through December 11, 1987, and February 1 through 10, 1988. The Survey is being conducted by a multidisciplinary team of environmental specialists led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team specialists are outside experts being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with SPR. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involved the review of existing site environmental data, observations of the operations carried on at SPR, and interviews with site personnel. The Survey team has developed a Sampling and Analysis Plan to assist in further assessing specific environmental problems identified during its on-site activities. The Sampling and Analysis Plan will be executed by Idaho National Engineering Laboratory. When completed, the results will be incorporated into the SPR Survey findings for inclusion into the Environmental Survey Summary Report. The Summary Report will reflect the final determinations of the SPR Survey and the other DOE site-specific Surveys. 200 refs., 50 figs., 30 tabs.

Reserve requirements and the bank lending channel in China

OpenAIRE

Fungácová , Zuzana; Nuutilainen , Riikka; Weill , Laurent

2015-01-01

This paper examines how reserve requirements influence the transmission of monetary policy through the bank lending channel in China while also taking into account the role of bank ownership. The implementation of Chinese monetary policy is characterized by the reliance on the reserve requirements as a regular policy tool with frequent adjustments. Using a large dataset of 170 Chinese banks for the period 2004–2013, we analyze the reaction of loan supply to changes in reserve requirements. We...

Fatigue strength of a single lap joint SPR-bonded

International Nuclear Information System (INIS)

Di Franco, G.; Fratini, L.; Pasta, A.

2011-01-01

In the last years, hybrid joints, meaning with this the joints which consist in combining a traditional mechanical joint to a layer of adhesive, are gradually attracting the attention of various sectors of the construction of vehicles and transportation industries, for their better performance compared to just mechanical joints (self-piercing riveting SPR, riveting, and so on) or just to bonded joints.The paper investigates the fatigue behavior of a single lap joint self-piercing riveted (SPR) and bonded throughout fatigue tests. The considered geometric configuration allowed the use of two rivets placed longitudinally; an epoxy resin was used as adhesive. In the first part of the work static characterization of the joints was carried out through tensile tests. Then fatigue tests were made with the application of different levels of load. The fatigue curves were also obtained at the varying the distance between the two rivets in order to better assess the joint strength for a given length of overlap.

Special awards lighten up SPR banquet

Science.gov (United States)

Zwickl, Ron; Baker, Dan; Reiff, Pat

On December 8, 1982, Marcia Neugebauer, then president of the Solar and Planetary Relationships section, held the “First Occasional Awards Ceremony” in conjunction with the annual dinner banquet at the Fall AGU meeting. These awards were an attempt to add a little humor to our usually somber gatherings. This year we reincarnated Neugebauer's successful concept and presented a number of new and novel awards to our fellow scientists at the Fall AGU SPR dinner. Summarized for your enjoyment are the categories and the official winners, as announced at the December 6 banquet.

The SPR detection of Salmonella enteritidis in food using aptamers as recongnition elements

Science.gov (United States)

Di, W. T.; Du, X. W.; Pan, M. F.; Wang, J. P.

2017-09-01

In this experiment, a fast, accurate, non-destructive, unmarked and simple-operation detection method for Salmonella enteritidis in food was established by the BI-3000 plasma resonance biosensor (SPR). This article establishes a method of using nucleic acid aptamer as immune recognition element in SPR which can be employed to detect Salmonella enteritidis in food for the first time. The experimental conditions were screened and the experimental scheme was validated and applied. The best flow rate was 5μL/min, the best concentration of the aptamers was 180mM, and the best regenerating solution was the 20mM NaOH. This method had almost no cross-reactivity. Besides, we established a standard curve of Salmonella enteritidis and SPR signal, with the detection limit of 2 cfu/mL. Finally, we tested the samples of chicken, pork, shrimp and fish purchased from supermarkets. The method has the advantages of short time, low detection limit and easy operation, which can be used for a large number of food samples.

THE EFFECT OF CHANGES IN RESERVE REQUIREMENTS DURING THE 1930s:

OpenAIRE

Thomas Mayer; Thomas F. Cargill

2004-01-01

The differential response of cash reserves of member banks and nonmember banks not subject to the 1936-37 increase in reserve requirements is estimated to determine whether the 1937-38 recession was caused by the increase in reserve requirements. We identify 17 states that maintained constant reserve requirements from June 1934 to June 1941. While member banks increased their cash reserve ratios relative to nonmember banks, the magnitude of the adjustment is too small to have contributed to t...

Geomechanical Simulation of Bayou Choctaw Strategic Petroleum Reserve - Model Calibration.

Energy Technology Data Exchange (ETDEWEB)

Park, Byoung [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2017-02-01

A finite element numerical analysis model has been constructed that consists of a realistic mesh capturing the geometries of Bayou Choctaw (BC) Strategic Petroleum Reserve (SPR) site and multi - mechanism deformation ( M - D ) salt constitutive model using the daily data of actual wellhead pressure and oil - brine interface. The salt creep rate is not uniform in the salt dome, and the creep test data for BC salt is limited. Therefore, the model calibration is necessary to simulate the geomechanical behavior of the salt dome. The cavern volumetric closures of SPR caverns calculated from CAVEMAN are used for the field baseline measurement. The structure factor, A 2 , and transient strain limit factor, K 0 , in the M - D constitutive model are used for the calibration. The A 2 value obtained experimentally from the BC salt and K 0 value of Waste Isolation Pilot Plant (WIPP) salt are used for the baseline values. T o adjust the magnitude of A 2 and K 0 , multiplication factors A2F and K0F are defined, respectively. The A2F and K0F values of the salt dome and salt drawdown skins surrounding each SPR cavern have been determined through a number of back fitting analyses. The cavern volumetric closures calculated from this model correspond to the predictions from CAVEMAN for six SPR caverns. Therefore, this model is able to predict past and future geomechanical behaviors of the salt dome, caverns, caprock , and interbed layers. The geological concerns issued in the BC site will be explained from this model in a follow - up report .

Geomechanical Model Calibration Using Field Measurements for a Petroleum Reserve

Science.gov (United States)

Park, Byoung Yoon; Sobolik, Steven R.; Herrick, Courtney G.

2018-03-01

A finite element numerical analysis model has been constructed that consists of a mesh that effectively captures the geometries of Bayou Choctaw (BC) Strategic Petroleum Reserve (SPR) site and multimechanism deformation (M-D) salt constitutive model using the daily data of actual wellhead pressure and oil-brine interface location. The salt creep rate is not uniform in the salt dome, and the creep test data for BC salt are limited. Therefore, the model calibration is necessary to simulate the geomechanical behavior of the salt dome. The cavern volumetric closures of SPR caverns calculated from CAVEMAN are used as the field baseline measurement. The structure factor, A 2, and transient strain limit factor, K 0, in the M-D constitutive model are used for the calibration. The value of A 2, obtained experimentally from BC salt, and the value of K 0, obtained from Waste Isolation Pilot Plant salt, are used for the baseline values. To adjust the magnitude of A 2 and K 0, multiplication factors A 2 F and K 0 F are defined, respectively. The A 2 F and K 0 F values of the salt dome and salt drawdown skins surrounding each SPR cavern have been determined through a number of back analyses. The cavern volumetric closures calculated from this model correspond to the predictions from CAVEMAN for six SPR caverns. Therefore, this model is able to predict behaviors of the salt dome, caverns, caprock, and interbed layers. The geotechnical concerns associated with the BC site from this analysis will be explained in a follow-up paper.

Detection of mycotoxins using imaging surface plasmon resonance (iSPR)

Science.gov (United States)

Significant progress has been made in the development of biosensors that can be used to detect mycotoxins. One technology that has been extensively tested is surface plasmon resonance (SPR). In 2003 a multi-toxin method was reported that detected aflatoxin B1 (AFB1), zearalenone (ZEA), fumonisin B1 ...

40 CFR 74.17 - Application requirements for process sources. [Reserved

Science.gov (United States)

2010-07-01

... requirements for process sources. [Reserved] ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Application requirements for process sources. [Reserved] 74.17 Section 74.17 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...

Estimation of optical constants of a bio-thin layer (onion epidermis), using SPR spectroscopy

International Nuclear Information System (INIS)

Rehman, Saif-ur-; Hayashi, Shinji; Sekkat, Zouheir; Mumtaz, Huma; Shaukat, S F

2014-01-01

We estimate the optical constants of a biological thin layer (Allium cepa) by surface plasmon resonance (SPR) spectroscopy. For this study, the fresh inner thin epidermis of an onion bulb was used and stacked directly on gold (Au) and silver (Ag) film surfaces in order to identify the shift in SPR mode of each metal film at an operating wavelength of 632.8 nm. The thickness and dielectric constants of the biological thin layer were determined by matching the experimental SPR curves to theoretical ones. The thickness and roughness of bare Au and Ag thin films were also measured by atomic force microscopy (AFM); the results of which are in good agreement with those obtained through experiment. Due to the high surface roughness of the natural onion epidermis layer, AFM could not measure the exact thickness of an onion epidermis. It is estimated that the value of the real part of the dielectric constant of an onion epidermis is between the dielectric constants of water and air. (paper)

Enhancement of chitosan-graphene oxide SPR sensor with a multi-metallic layers of Au–Ag–Au nanostructure for lead(II) ion detection

Energy Technology Data Exchange (ETDEWEB)

Kamaruddin, Nur Hasiba [Department of Electric, Electronic and Systems Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor (Malaysia); Bakar, Ahmad Ashrif A., E-mail: ashrif@ukm.edu.my [Department of Electric, Electronic and Systems Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor (Malaysia); Yaacob, Mohd Hanif; Mahdi, Mohd Adzir [Wireless and Photonic Network Research Centre, Faculty of Engineering, Universiti Putra Malaysia, 43400 Serdang, Selangor (Malaysia); Zan, Mohd Saiful Dzulkefly [Department of Electric, Electronic and Systems Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor (Malaysia); Shaari, Sahbudin [Institute of Microengineering and Nanoelectronics, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor (Malaysia)

2016-01-15

Highlights: • Tri-metallic Au–Ag–Au CS-GO SPR sensor was fabricated for the first time. • The tri-metallic nanostructure provided an enhanced evanescent field. • Successful functionalization of the CS-GO sensing layer. • Superior performance for lead(II) ion detection. - Abstract: We demonstrate the enhancement of surface plasmon resonance (SPR) technique by implementing a multi-metallic layers of Au–Ag–Au nanostructure in the chitosan-graphene oxide (CS-GO) SPR sensor for lead(II) ion detection. The performance of the sensor is analyzed via SPR measurements, from which the sensitivity, signal-to-noise ratio and repeatability are determined. The nanostructure layers are characterized using field emission scanning electron microscopy (FESEM), atomic force microscopy (AFM), X-ray diffraction (XRD), Raman spectroscopy and X-ray photoelectron spectroscopy (XPS). We showed that the proposed structure has increased the shift in the SPR angle up to 3.5° within the range of 0.1–1 ppm due to the enhanced evanescent field at the sensing layer-analyte interface. This sensor also exhibits great repeatability which benefits from the stable multi-metallic nanostructure. The SNR value of 0.92 for 5 ppm lead(II) ion solution and reasonable linearity range up to that concentration shows that the tri-metallic CS-GO SPR sensor gives a good response towards the lead(II) ion solution. The CS-GO SPR sensor is also sensitive to at least a 10{sup −5} change in the refractive index. The results prove that our proposed tri-metallic CS-GO SPR sensor demonstrates a strong performance and reliability for lead(II) ion detection in accordance with the standardized lead safety level for wastewater.

Assessment of the Available Drawdowns for Oil Storage Caverns at the West Hackberry SPR Site

Energy Technology Data Exchange (ETDEWEB)

Sobolik, Steven R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Geotechnology and Engineering Dept.

2016-03-01

The Department of Energy, in response to requests from the U.S. Congress, wishes to maintain an up-to-date table documenting the number of available full drawdowns of each of the caverns owned by the Strategic Petroleum Reserve. This information is important for assessing the SPR’s ability to deliver oil to domestic oil companies expeditiously if national or world events dictate a rapid sale and deployment of the oil reserves. What factors go into assessing available drawdowns? The evaluation of drawdown risks require the consideration of several factors regarding cavern and wellbore integrity and stability, including stress states caused by cavern geometry and operations, salt damage caused by dilatant and tensile stresses, the effect on enhanced creep on wellbore integrity, the sympathetic stress effect of operations on neighboring caverns. Based on the work over the past several months, a consensus has been built regarding the assessment of drawdown capabilities and risks for the SPR caverns. This paper draws upon the recently West Hackberry model upgrade and analyses to reevaluate and update the available drawdowns for each of those caverns. Similar papers for the Bryan Mound, Big Hill, and Bayou Choctaw papers will be developed as the upgrades to those analyses are completed. The rationale and documentation of the methodology is described in the remainder of this report, as are the updated estimates of available drawdowns for the West Hackberry caverns.

Prepare for an SpR interview.

Science.gov (United States)

Garner, J P; Heppell, P S J

2003-03-01

By the time you attend an interview for a military SpR number you should have no real problems but it pays to be prepared. Begin preparations early, reading widely and talk to as many people as possible. Your consultants will have a useful viewpoint on the proceedings and may be able to help you refine your answers to the common questions. Arrive at your interview in a smart and timely fashion and answer questions with confidence and common sense. Avoid confrontation and bluff and be courteous at all times, whatever you may be feeling inside and thank the interview panel as you leave.

Binding behavior of CRP and anti-CRP antibody analyzed with SPR and AFM measurement

International Nuclear Information System (INIS)

Lee, Soo-Keun; Kim, Hyun-Chul; Cho, Sang-Joon; Jeong, Sang Won; Jeon, Won Bae

2008-01-01

Atomic force microscope (AFM) was exploited to take picture of the molecular topology of C-reactive protein (CRP) in phosphate-buffered saline (PBS) solution. An explicit molecular image of CRP demonstrated a pentagonal structure composed of five subunits. Dimensions of the doughnut-shaped CRP molecule measured by AFM were about 25 nm in outside diameter and 10 nm in central pore diameter, and the height of CRP molecule was about 4 nm which was comparable to the value determined by X-ray crystallography. Bis(N-succinimido)-11,11'-dithiobis (undecyl succinate) (DSNHS) was synthesized for use as a linker for immobilizing anti-CRP antibody (anti-CRP) onto the gold surface of a surface plasmon resonance (SPR) sensor chip. DSNHS formed self-assembled monolayer (SAM) on the gold surface. By use of an AFM tip, a pattern of ditch was engraved within the SAM of DSNHS, and anti-CRP was immobilized on the engraved SAM through replacement of N-hydroxysuccinimide group on the outside surface of DSNHS by the amine group of anti-CRP. Formation of CRP/anti-CRP complex on the gold surface of SPR sensor chip was clearly demonstrated by measuring SPR angle shift. A consecutive series of SAM, SAM/anti-CRP, and SAM/anti-CRP/CRP complexes was generated on a SPR sensor chip, and the changes in depth of the ditch were monitored by taking AFM images of the complexes. Comparative analysis of the depth differences indicates that binding of CRP to anti-CRP occurs in a planar mode

How required reserve ratio affects distribution and velocity of money

Science.gov (United States)

Xi, Ning; Ding, Ning; Wang, Yougui

2005-11-01

In this paper the dependence of wealth distribution and the velocity of money on the required reserve ratio is examined based on a random transfer model of money and computer simulations. A fractional reserve banking system is introduced to the model where money creation can be achieved by bank loans and the monetary aggregate is determined by the monetary base and the required reserve ratio. It is shown that monetary wealth follows asymmetric Laplace distribution and latency time of money follows exponential distribution. The expression of monetary wealth distribution and that of the velocity of money in terms of the required reserve ratio are presented in a good agreement with simulation results.

Sonar atlas of caverns comprising the U.S. Strategic Petroleum Reserve. Volume 2, Big Hill Site, Texas.

Energy Technology Data Exchange (ETDEWEB)

Rautman, Christopher Arthur; Lord, Anna Snider

2007-08-01

Downhole sonar surveys from the four active U.S. Strategic Petroleum Reserve sites have been modeled and used to generate a four-volume sonar atlas, showing the three-dimensional geometry of each cavern. This volume 2 focuses on the Big Hill SPR site, located in southeastern Texas. Volumes 1, 3, and 4, respectively, present images for the Bayou Choctaw SPR site, Louisiana, the Bryan Mound SPR site, Texas, and the West Hackberry SPR site, Louisiana. The atlas uses a consistent presentation format throughout. The basic geometric measurements provided by the down-cavern surveys have also been used to generate a number of geometric attributes, the values of which have been mapped onto the geometric form of each cavern using a color-shading scheme. The intent of the various geometrical attributes is to highlight deviations of the cavern shape from the idealized cylindrical form of a carefully leached underground storage cavern in salt. The atlas format does not allow interpretation of such geometric deviations and anomalies. However, significant geometric anomalies, not directly related to the leaching history of the cavern, may provide insight into the internal structure of the relevant salt dome.

Sonar atlas of caverns comprising the U.S. Strategic Petroleum Reserve. Volume 1, Bayou Choctaw site, Louisiana.

Energy Technology Data Exchange (ETDEWEB)

Rautman, Christopher Arthur; Lord, Anna Snider

2007-10-01

Downhole sonar surveys from the four active U.S. Strategic Petroleum Reserve sites have been modeled and used to generate a four-volume sonar atlas, showing the three-dimensional geometry of each cavern. This volume 1 focuses on the Bayou Choctaw SPR site, located in southern Louisiana. Volumes 2, 3, and 4, respectively, present images for the Big Hill SPR site, Texas, the Bryan Mound SPR site, Texas, and the West Hackberry SPR site, Louisiana. The atlas uses a consistent presentation format throughout. The basic geometric measurements provided by the down-cavern surveys have also been used to generate a number of geometric attributes, the values of which have been mapped onto the geometric form of each cavern using a color-shading scheme. The intent of the various geometrical attributes is to highlight deviations of the cavern shape from the idealized cylindrical form of a carefully leached underground storage cavern in salt. The atlas format does not allow interpretation of such geometric deviations and anomalies. However, significant geometric anomalies, not directly related to the leaching history of the cavern, may provide insight into the internal structure of the relevant salt dome.

Sonar atlas of caverns comprising the U.S. Strategic Petroleum Reserve. Volume 3, Bryan Mound Site, Texas.

Energy Technology Data Exchange (ETDEWEB)

Rautman, Christopher Arthur; Lord, Anna Snider

2007-09-01

Downhole sonar surveys from the four active U.S. Strategic Petroleum Reserve sites have been modeled and used to generate a four-volume sonar atlas, showing the three-dimensional geometry of each cavern. This volume 3 focuses on the Bryan Mound SPR site, located in southeastern Texas. Volumes 1, 2, and 4, respectively, present images for the Bayou Choctaw SPR site, Louisiana, the Big Hill SPR site, Texas, and the West Hackberry SPR site, Louisiana. The atlas uses a consistent presentation format throughout. The basic geometric measurements provided by the down-cavern surveys have also been used to generate a number of geometric attributes, the values of which have been mapped onto the geometric form of each cavern using a color-shading scheme. The intent of the various geometrical attributes is to highlight deviations of the cavern shape from the idealized cylindrical form of a carefully leached underground storage cavern in salt. The atlas format does not allow interpretation of such geometric deviations and anomalies. However, significant geometric anomalies, not directly related to the leaching history of the cavern, may provide insight into the internal structure of the relevant salt dome.

Sonar atlas of caverns comprising the U.S. Strategic Petroleum Reserve. Volume 4, West Hackberry site, Louisiana.

Energy Technology Data Exchange (ETDEWEB)

Rautman, Christopher Arthur; Lord, Anna Snider

2007-09-01

Downhole sonar surveys from the four active U.S. Strategic Petroleum Reserve sites have been modeled and used to generate a four-volume sonar atlas, showing the three-dimensional geometry of each cavern. This volume 4 focuses on the West Hackberry SPR site, located in southwestern Louisiana. Volumes 1, 2, and 3, respectively, present images for the Bayou Choctaw SPR site, Louisiana, the Big Hill SPR site, Texas, and the Bryan Mound SPR site, Texas. The atlas uses a consistent presentation format throughout. The basic geometric measurements provided by the down-cavern surveys have also been used to generate a number of geometric attributes, the values of which have been mapped onto the geometric form of each cavern using a color-shading scheme. The intent of the various geometrical attributes is to highlight deviations of the cavern shape from the idealized cylindrical form of a carefully leached underground storage cavern in salt. The atlas format does not allow interpretation of such geometric deviations and anomalies. However, significant geometric anomalies, not directly related to the leaching history of the cavern, may provide insight into the internal structure of the relevant salt dome.

The Development of a Portable SPR Bioanalyzer for Sensitive Detection of Escherichia coli O157:H7

Directory of Open Access Journals (Sweden)

Shun Wang

2016-11-01

Full Text Available The purpose of this study was to develop a portable surface plasmon resonance (SPR bioanalyzer for the sensitive detection of Escherichia coli O157:H7 in comparison with an enzyme-linked immunosorbent assay (ELISA. The experimental setup mainly consisted of an integrated biosensor and a homemade microfluidic cell with a three-way solenoid valve. In order to detect Escherichia coli O157:H7 using the SPR immunoassay, 3-mercaptopropionic acid (3-MPA was chemisorbed onto a gold surface via covalent bond for the immobilization of biological species. 1-ethyl-3-(3-dimethylaminopropyl carbodiimide hydrochloride (EDC and N-hydroxysuccinimide (NHS were used as crosslinker reagents to enable the reaction between 3-MPA and Escherichia coli O157:H7 antibodies by covalent –CO–NH– amide bonding. The experimental results were obtained from the Escherichia coli O157:H7 positive samples prepared by 10-, 20-, 40-, 80-, and 160-fold dilution respectively, which show that a good linear relationship with the correlation coefficient R of 0.982 existed between the response units from the portable SPR bioanalyzer and the concentration of Escherichia coli O157:H7 positive samples. Moreover, the theoretical detection limit of 1.87 × 103 cfu/mL was calculated from the positive control samples. Compared with the Escherichia coli O157:H7 ELISA kit, the sensitivity of this portable SPR bioanalyzer is four orders of magnitude higher than the ELISA kit. The results demonstrate that the portable SPR bioanalyzer could provide an alternative method for the quantitative and sensitive determination of Escherichia coli O157:H7 in field.

LUSH-based SPR sensor for the detection of alcohols and pheromone

Science.gov (United States)

Lau, Hui-Chong; Lee, Yeon-Kyung; Kwon, Jae-Young; Sohn, Young-Soo; Lim, Jeong Ok

2013-05-01

Protein is a widely used sensing substrate in the biosensing technology. In the study conducted here, we used odorant binding protein, LUSH from Drosophila as a biosensing substrate in a miniaturized surface plasmon resonance (SPR) sensor. LUSH contains the specific alcohols binding sites, which mediates the detection of alcohols and pheromone. We first modified the surface of the gold sensor chip using the self assembled monolayer in the chloroform solution. The saturated concentration was determined prior to the detection of alcohols and pheromone at various concentrations. The results showed that the LUSH was saturated at 1000 μg/ml on the gold sensor chip. The detection response of LUSH was significant at higher concentration of alcohols. LUSH detected ethanol at concentration >=50% propanol was detected at >=25% whereas pheromone was detected at >=1.25 μg/μl. The results provide some fundamental information on the potential use of LUSH-based SPR as a simple and easy protein-based sensor in the near future.

Comparison of the CPU and memory performance of StatPatternRecognitions (SPR) and Toolkit for MultiVariate Analysis (TMVA)

International Nuclear Information System (INIS)

Palombo, G.

2012-01-01

High Energy Physics data sets are often characterized by a huge number of events. Therefore, it is extremely important to use statistical packages able to efficiently analyze these unprecedented amounts of data. We compare the performance of the statistical packages StatPatternRecognition (SPR) and Toolkit for MultiVariate Analysis (TMVA). We focus on how CPU time and memory usage of the learning process scale versus data set size. As classifiers, we consider Random Forests, Boosted Decision Trees and Neural Networks only, each with specific settings. For our tests, we employ a data set widely used in the machine learning community, “Threenorm” data set, as well as data tailored for testing various edge cases. For each data set, we constantly increase its size and check CPU time and memory needed to build the classifiers implemented in SPR and TMVA. We show that SPR is often significantly faster and consumes significantly less memory. For example, the SPR implementation of Random Forest is by an order of magnitude faster and consumes an order of magnitude less memory than TMVA on Threenorm data.

Vurdering af omfang og konsekvenser af sprøjtning og gødskning af § 3-beskyttede naturarealer

DEFF Research Database (Denmark)

Strandberg, Morten Tune; Bak, Jesper Leth; Bladt, Jesper Stentoft

2012-01-01

Det er overvejende de ferske enge, der gødskes og sprøjtes, hvorimod dette kun undtagelsesvist er konstateret på andre naturtyper som overdrev og heder m.m. De ferske enge er samtidig den mest udbredte § 3-naturtype. Behandling i form af gødskning og sprøjtning foregår anslået på op til 20 % af a...

How Required Reserve Ratio Affects Distribution and Velocity of Money

OpenAIRE

Xi, Ning; Ding, Ning; Wang, Yougui

2005-01-01

In this paper the dependence of wealth distribution and the velocity of money on the required reserve ratio is examined based on a random transfer model of money and computer simulations. A fractional reserve banking system is introduced to the model where money creation can be achieved by bank loans and the monetary aggregate is determined by the monetary base and the required reserve ratio. It is shown that monetary wealth follows asymmetric Laplace distribution and latency time of money fo...

21 CFR 111.83 - What are the requirements for reserve samples?

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What are the requirements for reserve samples? 111..., PACKAGING, LABELING, OR HOLDING OPERATIONS FOR DIETARY SUPPLEMENTS Requirement to Establish a Production and Process Control System § 111.83 What are the requirements for reserve samples? (a) You must collect and...

Use and Limitations of the Reserve Requirement Policy in Montenegro

Directory of Open Access Journals (Sweden)

Milošević Velibor

2014-05-01

Full Text Available Since reserve requirement is the only monetary policy instrument used in Montenegro, it has been subject to frequent amendments since the global crisis outbreak. The analysis of the monetary demand model showed that there is an active transmission mechanism of change in the reserve requirement rate on the deposits trend reflects on lending activity. Also, there is a significant impact of FDIs on deposits trending in the banking system, as well as the positive impact of turnover on stock exchange on the deposits and loans trend. Finally, it was found that the financial crisis has caused negative trends in loans and deposits. On the other hand, the impact of changes in the reserve requirement on the economic activity in Montenegro could not be determined. This is primarily due to the fact that the transmission mechanism of the effect of reserve requirement on economic activity is too long to be able to estimate the model that does not allow the dynamics of the independent variables. The second reason is that industrial output index is only an indirect indicator of the economic activity.

12 CFR 208.35 - Qualification requirements for transactions in certain securities. [Reserved

Science.gov (United States)

2010-01-01

... requirements for transactions in certain securities. [Reserved] ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Qualification requirements for transactions in certain securities. [Reserved] 208.35 Section 208.35 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF...

Did Doubling Reserve Requirements Cause the Recession of 1937-1938? A Microeconomic Approach

OpenAIRE

Charles W. Calomiris; Joseph Mason; David Wheelock

2011-01-01

In 1936-37, the Federal Reserve doubled the reserve requirements imposed on member banks. Ever since, the question of whether the doubling of reserve requirements increased reserve demand and produced a contraction of money and credit, and thereby helped to cause the recession of 1937-1938, has been a matter of controversy. Using microeconomic data to gauge the fundamental reserve demands of Fed member banks, we find that despite being doubled, reserve requirements were not binding on bank re...

SPR based hybrid electro-optic biosensor for β-lactam antibiotics determination in water

Science.gov (United States)

Galatus, Ramona; Feier, Bogdan; Cristea, Cecilia; Cennamo, Nunzio; Zeni, Luigi

2017-09-01

The present work aims to provide a hybrid platform capable of complementary and sensitive detection of β-lactam antibiotics, ampicillin in particular. The use of an aptamer specific to ampicillin assures good selectivity and sensitivity for the detection of ampicillin from different matrice. This new approach is dedicated for a portable, remote sensing platform based on low-cost, small size and low-power consumption solution. The simple experimental hybrid platform integrates the results from the D-shape surface plasmon resonance plastic optical fiber (SPR-POF) and from the electrochemical (bio)sensor, for the analysis of ampicillin, delivering sensitive and reliable results. The SPR-POF already used in many previous applications is embedded in a new experimental setup with fluorescent fibers emitters, for broadband wavelength analysis, low-power consumption and low-heating capabilities of the sensing platform.

Empirical analysis of optimal strategic petroleum reserve in China

International Nuclear Information System (INIS)

Wei, Yi-Ming; Wu, Gang; Liu, Lan-Cui; Fan, Ying

2008-01-01

The Chinese government began to prepare for the establishment of strategic petroleum reserve in March 2004. Therefore, answering the question of what level of strategic petroleum reserve would be suitable for China's future economic development becomes essential. Using a decision tree model based on a cost function, this paper quantifies China's optimal strategic petroleum reserve for the period 2005-2020. This approach provides a methodology reference for further quantified discussion on China's SPR. Our results show that: for economic development and security of the energy supply, the strategic petroleum reserve should be the equivalent of 30-60 days of net oil import for an optimal solution, when the oil price is $ 50/bbl; with a reserve of an equivalent of 60-90 days of net oil import to have an optimal solution when oil price is $20-35/bbl. (author)

Evaluation of Gd{sub 2}O{sub 2}S:Pr granular phosphor properties for X-ray mammography imaging

Energy Technology Data Exchange (ETDEWEB)

David, S.; Michail, C. [Department of Biomedical Engineering, Technological Educational Institute (TEI) of Athens, Ag. Spyridonos Street, 122 10 Egaleo (Greece); Seferis, I. [Department of Biomedical Engineering, Technological Educational Institute (TEI) of Athens, Ag. Spyridonos Street, 122 10 Egaleo (Greece); Faculty of Chemistry, Wroclaw University, 14F Joliot-Curie Street, 50-383 Wroclaw (Poland); Valais, I.; Fountos, G.; Liaparinos, P.; Kandarakis, I. [Department of Biomedical Engineering, Technological Educational Institute (TEI) of Athens, Ag. Spyridonos Street, 122 10 Egaleo (Greece); Kalyvas, N., E-mail: nkalyvas@teiath.gr [Department of Biomedical Engineering, Technological Educational Institute (TEI) of Athens, Ag. Spyridonos Street, 122 10 Egaleo (Greece)

2016-01-15

Phosphor materials are widely used in X-ray medical imaging detector applications, coupled with suitable photoreceptors. Upon the most demanding imaging modality is X-ray mammography, since the best defense against breast cancer is its early detection. A material suitable as a mammographic detector should efficiently absorb X-ray photons and transform them to optical photons, so as to minimize breast dose. The aim of the present study was to investigate the X-ray absorption efficiency and the absolute efficiency (AE), defined as the output optical photon power divided by the incident exposure, of Gd{sub 2}O{sub 2}S:Pr powder scintillator. For the purposes of this study, three scintillating screens with coating thicknesses, 34.1, 46.0 and 81.5 mg/cm{sup 2} respectively, were prepared in our laboratory from Gd{sub 2}O{sub 2}S:Pr powder (Phosphor Technology, Ltd.) by sedimentation on silica substrates. The quantum detection efficiency (QDE), the energy absorption efficiency (EAE), the spectral matching factor and the absolute efficiency (AE) were evaluated for X-ray mammographic conditions. Furthermore theoretical models were utilized to investigate the optical photon transmission properties through the phosphor mass. Gd{sub 2}O{sub 2}S:Pr presented high X-ray absorption properties and good spectral compatibility with several photoreceptors. It may be utilized for X-ray mammographic imaging if it is put in conjunction with a sensitive photoreceptor, so as to enhance Gd{sub 2}O{sub 2}S:Pr light emission properties. - Highlights: • Gd{sub 2}O{sub 2}S:Pr phosphor evaluated for mammography detectors. • The X-ray absorption efficiency was found high. • Spectral matching compatibility found for several photoreceptors. • X-ray absolute efficiency measured smaller than other phosphors. • Optical diffusion length and the light transmission per layer was theoretically calculated.

Configuration-controlled Au nanocluster arrays on inverse micelle nano-patterns: versatile platforms for SERS and SPR sensors

Science.gov (United States)

Jang, Yoon Hee; Chung, Kyungwha; Quan, Li Na; Špačková, Barbora; Šípová, Hana; Moon, Seyoung; Cho, Won Joon; Shin, Hae-Young; Jang, Yu Jin; Lee, Ji-Eun; Kochuveedu, Saji Thomas; Yoon, Min Ji; Kim, Jihyeon; Yoon, Seokhyun; Kim, Jin Kon; Kim, Donghyun; Homola, Jiří; Kim, Dong Ha

2013-11-01

Nanopatterned 2-dimensional Au nanocluster arrays with controlled configuration are fabricated onto reconstructed nanoporous poly(styrene-block-vinylpyridine) inverse micelle monolayer films. Near-field coupling of localized surface plasmons is studied and compared for disordered and ordered core-centered Au NC arrays. Differences in evolution of the absorption band and field enhancement upon Au nanoparticle adsorption are shown. The experimental results are found to be in good agreement with theoretical studies based on the finite-difference time-domain method and rigorous coupled-wave analysis. The realized Au nanopatterns are exploited as substrates for surface-enhanced Raman scattering and integrated into Kretschmann-type SPR sensors, based on which unprecedented SPR-coupling-type sensors are demonstrated.Nanopatterned 2-dimensional Au nanocluster arrays with controlled configuration are fabricated onto reconstructed nanoporous poly(styrene-block-vinylpyridine) inverse micelle monolayer films. Near-field coupling of localized surface plasmons is studied and compared for disordered and ordered core-centered Au NC arrays. Differences in evolution of the absorption band and field enhancement upon Au nanoparticle adsorption are shown. The experimental results are found to be in good agreement with theoretical studies based on the finite-difference time-domain method and rigorous coupled-wave analysis. The realized Au nanopatterns are exploited as substrates for surface-enhanced Raman scattering and integrated into Kretschmann-type SPR sensors, based on which unprecedented SPR-coupling-type sensors are demonstrated. Electronic supplementary information (ESI) available: TEM image and UV-vis absorption spectrum of citrate-capped Au NPs, AFM images of Au NC arrays on the PS-b-P4VP (41k-24k) template, ImageJ-analyzed results of PS-b-P4VP (41k-24k)-templated Au NC arrays, calculated %-surface coverage values, SEM images of Au NC arrays on the PS-b-P2VP (172k-42k

26 CFR 1.6031(b)-2T - REMIC reporting requirements (temporary). [Reserved

Science.gov (United States)

2010-04-01

... requirements (temporary). [Reserved] ... 26 Internal Revenue 13 2010-04-01 2010-04-01 false REMIC reporting requirements (temporary). [Reserved] 1.6031(b)-2T Section 1.6031(b)-2T Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE...

Comparative SPR study on the effect of nanomaterials on the biological activity of adsorbed proteins

International Nuclear Information System (INIS)

Mei, Q.; Chen, Y.; Hong, J.; Chen, H.; Ding, X.; Yin, Y.; Koh, K.; Lee, J.

2012-01-01

Bioactivity of proteins is evaluated to test the adverse effects of nanoparticles interjected into biological systems. Surface plasmon resonance (SPR) spectroscopy detects binding affinity that is normally related to biological activity. Utilizing SPR spectroscopy, a concise testing matrix is established by investigating the adsorption level of bovine serum albumin (BSA) and anti-BSA on the surface covered with 11-mercaptoundecanoic acid (MUA); magnetic nanoparticles (MNPs) and single-walled carbon nanotubes (SWCNTs), respectively. The immunoactivity of BSA on MNPs and SWCNT decreased by 18 % and 5 %, respectively, compared to that on the gold film modified with MUA. This indicates that MNPs cause a considerable loss of biological activity of adsorbed protein. This effect can be utilized for practical applications on detailed biophysical research and nanotoxicity studies. (author)

Inflation Targeting and Quantitative Tightening: Effects of Reserve Requirements in Peru

OpenAIRE

Adrián Armas; Paul Castillo; Marco Vega

2014-01-01

This paper provides an overview of the reserve requirement measures undertaken by the Central Bank of Peru. It provides a rationale for the use of these instruments as well as empirical evidence of their effectiveness. In general, the results show that tightening reserve requirements has the desired effects on interest rates and credit levels at both banks and smaller financial institutions (cajas municipales).

Stability Modification of SPR Silver Nano-Chips by Alkaline Condensation of Aminopropyltriethoxysilane

Directory of Open Access Journals (Sweden)

M. Ghorbanpour

2015-04-01

Full Text Available The Silver SPR chip was modified by alkaline-silane condensation with aminopropyltriethoxysilane (APTES in NaOH aqueous solution at different times. Silver sputtered slides coated with APTES were immersed in NaOH solution, enabling us to produce silver surfaces homogeneously covered with APTES. The surface properties of grafted APTES on sputtered silver surface as a occasion of time were studied using SPR analysis, AFM and contact angle measurement. The mechanical and chemical stability of samples was assayed by tape test and NaCl test. The answers show that hydrolysis and condensation of APTES are activated in alkaline solution and lead to formation of a protective APTES layer on the surface of silver. The morphology of APTES on silver surface is a function of coverage density that is altered by changing time. At short times (< 30 min, APTES molecules physically adsorb to the surface leads to weak protection. At higher condensation times, APTES molecules chemically bond to the surface and each other leads to better protection.

Near Infrared Characterization of Hetero-Core Optical Fiber SPR Sensors Coated with Ta2O5 Film and Their Applications

Directory of Open Access Journals (Sweden)

Kazuhiro Watanabe

2012-02-01

Full Text Available This paper describes the characteristics of optical fiber sensors with surface plasmon resonance (SPR at 1,310 nm in which the scattering loss of silica optical fiber is low. SPR operation in the infrared wavelength range is achieved by coating a thin tantalum pentaoxide (Ta2O5 film. The novelty of this paper lies in the verification of how the hetero-core scheme could be operated as a commercial base candidate in the sense of easy fabrication, sufficient mechanical strength, and significant sensitivity as a liquid detector under the basis of a low loss transmission network in the near infrared wavelength region. The effect of Ta2O5 layer thickness has been experimentally revealed in the wavelength region extending to 1,800 nm by using the hetero-core structured optical fiber. SPR characterizations have been made in the wavelength region 1,000–1,300 nm, showing the feasible operation at the near infrared wavelength and the possible practical applications. In addition, the technique developed in this work has been interestingly applied to a multi-point water-detection and a water-level gauge in which tandem-connected SPR sensors system using hetero-core structured fibers were incorporated. The detailed performance characteristics are also shown on these applications.

Analysis of cavern stability at the West Hackberry SPR site.

Energy Technology Data Exchange (ETDEWEB)

Ehgartner, Brian L.; Sobolik, Steven Ronald

2009-05-01

This report presents computational analyses that simulate the structural response of caverns at the Strategic Petroleum Reserve (SPR) West Hackberry site. The cavern field comprises 22 caverns. Five caverns (6, 7, 8, 9, 11) were acquired from industry and have unusual shapes and a history dating back to 1946. The other 17 caverns (101-117) were leached according to SPR standards in the mid-1980s and have tall cylindrical shapes. The history of the caverns and their shapes are simulated in a three-dimensional geomechanics model of the site that predicts deformations, strains, and stresses. Future leaching scenarios corresponding to oil drawdowns using fresh water are also simulated by increasing the volume of the caverns. Cavern pressures are varied in the model to capture operational practices in the field. The results of the finite element model are interpreted to provide information on the current and future status of subsidence, well integrity, and cavern stability. The most significant results in this report are relevant to Cavern 6. The cavern is shaped like a bowl with a large ceiling span and is in close proximity to Cavern 9. The analyses predict tensile stresses at the edge of the ceiling during repressuization of Cavern 6 following workover conditions. During a workover the cavern is at low pressure to service a well. The wellhead pressures are atmospheric. When the workover is complete, the cavern is repressurized. The resulting elastic stresses are sufficient to cause tension around the edge of the large ceiling span. With time, these stresses relax to a compressive state because of salt creep. However, the potential for salt fracture and propagation exists, particularly towards Cavern 9. With only 200 ft of salt between the caverns, the operational consequences must be examined if the two caverns become connected. A critical time may be during a workover of Cavern 9 in part because of the operational vulnerabilities, but also because dilatant damage is

Reserve requirements and double Bertrand competition among banks

NARCIS (Netherlands)

Toolsema-Veldman, Linda

The paper considers a model of double Bertrand competition among banks, in which banks compete for deposits as well as loans. It is shown that the introduction of reserve requirements can have an effect on the existence and efficiency properties of Nash equilibria of this model. This provides a new

Environmental Assessment for decommissioning the Strategic Petroleum Reserve Weeks Island Facility, Iberia Parish, Louisiana

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-12-01

The Strategic Petroleum Reserve (SPR) Weeks Island site is one of five underground salt dome crude oils storage facilities operated by the Department of Energy (DOE). It is located in Iberia Parish, Louisiana. The purpose of the proposed action is to decommission the Weeks Island crude oil storage after the oil inventory has been transferred to other SPR facilities. Water intrusion into the salt dome storage chambers and the development of two sinkholes located near the aboveground facilities has created uncertain geophysical conditions. This Environmental Assessment describes the proposed decommissioning operation, its alternatives, and potential environmental impacts. Based on this analyses, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) and has issued the Finding of No Significant Impact (FONSI).

Environmental Assessment for decommissioning the Strategic Petroleum Reserve Weeks Island Facility, Iberia Parish, Louisiana

International Nuclear Information System (INIS)

1995-12-01

The Strategic Petroleum Reserve (SPR) Weeks Island site is one of five underground salt dome crude oils storage facilities operated by the Department of Energy (DOE). It is located in Iberia Parish, Louisiana. The purpose of the proposed action is to decommission the Weeks Island crude oil storage after the oil inventory has been transferred to other SPR facilities. Water intrusion into the salt dome storage chambers and the development of two sinkholes located near the aboveground facilities has created uncertain geophysical conditions. This Environmental Assessment describes the proposed decommissioning operation, its alternatives, and potential environmental impacts. Based on this analyses, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) and has issued the Finding of No Significant Impact (FONSI)

Reflectance spectra characteristics from an SPR grating fabricated by nano-imprint lithography technique for biochemical nanosensor applications

Science.gov (United States)

Setiya Pradana, Jalu; Hidayat, Rahmat

2018-04-01

In this paper, we report our research work on developing a Surface Plasmon Resonance (SPR) element with sub-micron (hundreds of nanometers) periodicity grating structure. This grating structure was fabricated by using a simple nano-imprint lithography technique from an organically siloxane polymers, which was then covered by nanometer thin gold layer. The formed grating structure was a very well defined square-shaped periodic structure. The measured reflectance spectra indicate the SPR wave excitation on this grating structure. For comparison, the simulations of reflectance spectra have been also carried out by using Rigorous Coupled-Wave Analysis (RCWA) method. The experimental results are in very good agreement with the simulation results.

Development of a β-Lactoglobulin Sensor Based on SPR for Milk Allergens Detection

DEFF Research Database (Denmark)

Ashley, Jon; D'Aurelio, Roberta; Piekarska, Monika

2018-01-01

A sensitive and label-free surface plasmon resonance (SPR) based sensor was developed in this work for the detection of milk allergens. β-lactoglobulin (BLG) protein was used as the biomarker for cow milk detection. This is to be used directly in final rinse samples of cleaning in-place (CIP) sys...

A SPR-based immunosensor for the detection of isoproturon.

Science.gov (United States)

Gouzy, Marie-Françoise; Kess, Melanie; Krämer, Petra M

2009-02-15

The proof of principle of a reusable surface plasmon resonance (SPR)-based immunosensor for the monitoring of isoproturon (IPU), a selective and systemic herbicide, is presented. The detecting rat monoclonal anti-isoproturon antibody (mAb IOC 7E1) was reversibly immobilized through the use of a capture mouse anti-rat (kappa-chain) monoclonal antibody (mAb TIB 172), which was covalently immobilized on the sensor chip surface. Such strategy features a controlled binding of the captured detecting antibody as well as facilitates the surface regeneration. The capture of the anti-IPU mAb by the antibody (TIB 172) coated sensor surface could be carried out up to 120 times (immobilization/regeneration cycles) without any evidence of activity loss. With a high test midpoint and a low associated SPR signal, the direct detection format was shown to be unsuitable for the routine analysis of isoproturon. However, the limit of detection (LOD) could be easily enhanced by using a strategy based on a surface competition assay, which improved all immunosensor parameters. Moreover, the sensitivity and working range of the indirect format were found to be dependent on the surface density of the anti-IPU mAb IOC 7E1. As expected for competitive formats, the lowest surface coverage (0.5 ng/mm(2)) allowed a lower detection of the herbicide isoproturon with a calculated LOD of 0.1 microg/l, an IC(50) (50% inhibition) of 5.3+/-0.6 microg/l, and a working range (20-80% inhibition) of 1.3-16.3 microg/l.

13 CFR 120.847 - Requirements for the Loan Loss Reserve Fund (LLRF).

Science.gov (United States)

2010-01-01

... Requirements for the Loan Loss Reserve Fund (LLRF). (a) General. PCLP CDCs must establish and maintain a LLRF... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Requirements for the Loan Loss Reserve Fund (LLRF). 120.847 Section 120.847 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION...

Developmentally-Regulated Excision of the SPβ Prophage Reconstitutes a Gene Required for Spore Envelope Maturation in Bacillus subtilis

Science.gov (United States)

Abe, Kimihiro; Kawano, Yuta; Iwamoto, Keito; Arai, Kenji; Maruyama, Yuki; Eichenberger, Patrick; Sato, Tsutomu

2014-01-01

Temperate phages infect bacteria by injecting their DNA into bacterial cells, where it becomes incorporated into the host genome as a prophage. In the genome of Bacillus subtilis 168, an active prophage, SPβ, is inserted into a polysaccharide synthesis gene, spsM. Here, we show that a rearrangement occurs during sporulation to reconstitute a functional composite spsM gene by precise excision of SPβ from the chromosome. SPβ excision requires a putative site-specific recombinase, SprA, and an accessory protein, SprB. A minimized SPβ, where all the SPβ genes were deleted, except sprA and sprB, retained the SPβ excision activity during sporulation, demonstrating that sprA and sprB are necessary and sufficient for the excision. While expression of sprA was observed during vegetative growth, sprB was induced during sporulation and upon mitomycin C treatment, which triggers the phage lytic cycle. We also demonstrated that overexpression of sprB (but not of sprA) resulted in SPβ prophage excision without triggering the lytic cycle. These results suggest that sprB is the factor that controls the timing of phage excision. Furthermore, we provide evidence that spsM is essential for the addition of polysaccharides to the spore envelope. The presence of polysaccharides on the spore surface renders the spore hydrophilic in water. This property may be beneficial in allowing spores to disperse in natural environments via water flow. A similar rearrangement occurs in Bacillus amyloliquefaciens FZB42, where a SPβ-like element is excised during sporulation to reconstitute a polysaccharide synthesis gene, suggesting that this type of gene rearrangement is common in spore-forming bacteria because it can be spread by phage infection. PMID:25299644

Study of Immobilization Procedure on Silver Nanolayers and Detection of Estrone with Diverged Beam Surface Plasmon Resonance (SPR Imaging

Directory of Open Access Journals (Sweden)

Ibrahim Abdulhalim

2013-03-01

Full Text Available An immobilization protocol was developed to attach receptors on smooth silver thin films. Dense and packed 11-mercaptoundecanoic acid (11-MUA was used to avoid uncontrolled sulfidization and harmful oxidation of silver nanolayers. N,N'-dicyclohexylcarbodiimide (DCC and N-hydroxysuccinimide (NHS were added to make the silver surfaces reactive. A comparative study was carried out with different immersion times of silver samples in 11-MUA solutions with different concentrations to find the optimum conditions for immobilization. The signals, during each step of the protocol, were analyzed with a refractometer based on the surface plasmon resonance (SPR effect and luminescence techniques. Molecular interactions at the surfaces between the probe and target at the surface nanolayer shift the SPR signal, thus indicating the presence of the substance. To demonstrate specific biosensing, rabbit anti-estrone polyclonal immunoglobulin G (IgG antibody was immobilized through a linker on 47 nm silver layer deposited on SF11 glass. At the final stage, the representative endocrine disruptor—estrone—was attached and detected in deionized water with a diverging beam SPR imaging sensor.

Improving Deterministic Reserve Requirements for Security Constrained Unit Commitment and Scheduling Problems in Power Systems

Science.gov (United States)

Wang, Fengyu

Traditional deterministic reserve requirements rely on ad-hoc, rule of thumb methods to determine adequate reserve in order to ensure a reliable unit commitment. Since congestion and uncertainties exist in the system, both the quantity and the location of reserves are essential to ensure system reliability and market efficiency. The modeling of operating reserves in the existing deterministic reserve requirements acquire the operating reserves on a zonal basis and do not fully capture the impact of congestion. The purpose of a reserve zone is to ensure that operating reserves are spread across the network. Operating reserves are shared inside each reserve zone, but intra-zonal congestion may block the deliverability of operating reserves within a zone. Thus, improving reserve policies such as reserve zones may improve the location and deliverability of reserve. As more non-dispatchable renewable resources are integrated into the grid, it will become increasingly difficult to predict the transfer capabilities and the network congestion. At the same time, renewable resources require operators to acquire more operating reserves. With existing deterministic reserve requirements unable to ensure optimal reserve locations, the importance of reserve location and reserve deliverability will increase. While stochastic programming can be used to determine reserve by explicitly modelling uncertainties, there are still scalability as well as pricing issues. Therefore, new methods to improve existing deterministic reserve requirements are desired. One key barrier of improving existing deterministic reserve requirements is its potential market impacts. A metric, quality of service, is proposed in this thesis to evaluate the price signal and market impacts of proposed hourly reserve zones. Three main goals of this thesis are: 1) to develop a theoretical and mathematical model to better locate reserve while maintaining the deterministic unit commitment and economic dispatch

21 CFR 111.465 - What requirements apply to holding reserve samples of dietary supplements?

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What requirements apply to holding reserve samples... Distributing § 111.465 What requirements apply to holding reserve samples of dietary supplements? (a) You must hold reserve samples of dietary supplements in a manner that protects against contamination and...

Nanoscale Affinity Chip Interface for Coupling Inhibition SPR Immunosensor Screening with Nano-LC TOF MS

NARCIS (Netherlands)

Marchesini, G.R.; Buijs, J.; Haasnoot, W.; Hooijerink, H.; Jansson, O.; Nielen, M.W.F.

2008-01-01

The on-line nanoscale coupling of a surface plasmon resonance (SPR)-based inhibition biosensor immunoassay (iBIA) for the screening of low molecular weight molecules with nano-liquid-chromatography electrospray ionization time-of-flight mass spectrometry (nano-LC ESI TOF MS) for identification is

26 CFR 1.411(d)-1 - Coordination of vesting and discrimination requirements. [Reserved

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 5 2010-04-01 2010-04-01 false Coordination of vesting and discrimination requirements. [Reserved] 1.411(d)-1 Section 1.411(d)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF... Plans, Etc. § 1.411(d)-1 Coordination of vesting and discrimination requirements. [Reserved] ...

SPR Characteristics Curve and Distribution of Residual Stress in Self-Piercing Riveted Joints of Steel Sheets

Directory of Open Access Journals (Sweden)

Rezwanul Haque

2017-01-01

Full Text Available Neutron diffraction was used to describe the residual stress distributions in self-piercing riveted (SPR joints. The sheet material displayed a compressive residual stress near the joint, and the stress gradually became tensile in the sheet material far away from the joint. The stress in the rivet leg was lower in the thick joint of the softer steel sheet than in the thin joint of the harder steel sheet. This lower magnitude was attributed to the lower force gradient during the rivet flaring stage of the SPR process curve. This study shows how the residual stress results may be related to the physical occurrences that happened during joining, using the characteristics curve. The study also shows that neutron diffraction technique enabled a crack in the rivet tip to be detected which was not apparent from a cross-section.

Comparison between a Direct-Flow SPR Immunosensor for Ampicillin and a Competitive Conventional Amperometric Device: Analytical Features and Possible Applications to Real Samples

Science.gov (United States)

Tomassetti, Mauro; Merola, Giovanni; Martini, Elisabetta; Campanella, Luigi; Sanzò, Gabriella; Favero, Gabriele; Mazzei, Franco

2017-01-01

In this research, we developed a direct-flow surface plasmon resonance (SPR) immunosensor for ampicillin to perform direct, simple, and fast measurements of this important antibiotic. In order to better evaluate the performance, it was compared with a conventional amperometric immunosensor, working with a competitive format with the aim of finding out experimental real advantages and disadvantages of two respective methods. Results showed that certain analytical features of the new SPR immunodevice, such as the lower limit of detection (LOD) value and the width of the linear range, are poorer than those of a conventional amperometric immunosensor, which adversely affects the application to samples such as natural waters. On the other hand, the SPR immunosensor was more selective to ampicillin, and measurements were more easily and quickly attained compared to those performed with the conventional competitive immunosensor. PMID:28394296

Improving the performance of brine wells at Gulf Coast strategic petroleum reserve sites

Energy Technology Data Exchange (ETDEWEB)

Owen, L.B.; Quong, R. (eds.)

1979-11-05

At the request of the Department of Energy, field techniques were developed to evaluate and improve the injection of brine into wells at Strategic Petroleum Reserve (SPR) sites. These wells are necessary for the disposal of saturated brine removed from salt domes where oil is being stored. The wells, which were accepting brine at 50 percent or less of their initial design rates, were impaired by saturated brine containing particulates that deposited on the sand face and in the geologic formation next to the wellbore. Corrosion of the brine-disposal pipelines and injection wells contributed to the impairment by adding significant amounts of particulates in the form of corrosion products. When tests were implemented at the SPR sites, it was found that the poor quality of injected brines was the primary cause of impaired injection; that granular-media filtration, when used with chemical pretreatment, is an effective method for removing particulates from hypersaline brine; that satisfactory injection-well performance can be attained with prefiltered brines; and that corrosion rates can be substantially reduced by oxygen-scavenging.

Immobilization of flavan-3-ols onto sensor chips to study their interactions with proteins and pectins by SPR

Energy Technology Data Exchange (ETDEWEB)

Watrelot, Aude A., E-mail: aude.watrelot@avignon.inra.fr [INRA, UMR408 Sécurité et Qualité des Produits d’Origine Végétale, Domaine St Paul, Site Agroparc, 84914 Avignon (France); Université d’Avignon, UMR408 Sécurité et Qualité des Produits d' Origine Végétale, F-84000 Avignon (France); Tran, Dong Tien [Université de Bordeaux, Institut des Sciences Moléculaires (UMR-CNRS 5255), 351 cours de la Libération, 33405 Talence (France); Institut Européen de Chimie et Biologie (IECB), 2 rue Robert Escarpit, 33607 Pessac (France); Buffeteau, Thierry [Université de Bordeaux, Institut des Sciences Moléculaires (UMR-CNRS 5255), 351 cours de la Libération, 33405 Talence (France); Deffieux, Denis [Université de Bordeaux, Institut des Sciences Moléculaires (UMR-CNRS 5255), 351 cours de la Libération, 33405 Talence (France); Institut Européen de Chimie et Biologie (IECB), 2 rue Robert Escarpit, 33607 Pessac (France); and others

2016-05-15

Highlights: • Flavanol-macromolecule interactions were determined using SPR. • Flavanols were chemically modified with a linker bearing a thiol group. • Flavanols were immobilized onto a carboxymethyl dextran surface. • Citrus pectin interacted more with flavanols than apple pectin. • Epicatechin interacted more with BSA than flavanol oligomer. - Abstract: Interactions between plant polyphenols and biomacromolecules such as proteins and pectins have been studied by several methods in solution (e.g. isothermal titration calorimetry, dynamic light scattering, nuclear magnetic resonance and spectrophotometry). Herein, these interactions were investigated in real time by Surface Plasmon Resonance (SPR) analysis after immobilization of flavan-3-ols onto a sensor chip surface. (−)-epicatechin, (+)-catechin and flavan-3-ol oligomers with an average degree of polymerization of 2 and 8 were chemically modified using N-(2-(tritylthio)ethyl)propiolamide in order to introduce a spacer unit onto the catecholic B ring. Modified flavan-3-ols were then immobilized onto a carboxymethylated dextran surface (CM5). Immobilization was validated and further verified by evaluating flavan-3-ol interaction with bovine serum albumin (BSA), poly-L-proline or commercial pectins. BSA was found to have a stronger association with monomeric flavan-3-ols than oligomers. SPR analysis of selected flavan-3-ols immobilized onto CM5 sensor chips showed a stronger association for citrus pectins than apple pectins, regardless of flavan-3-ol degree of polymerization.

Immobilization of flavan-3-ols onto sensor chips to study their interactions with proteins and pectins by SPR

International Nuclear Information System (INIS)

Watrelot, Aude A.; Tran, Dong Tien; Buffeteau, Thierry; Deffieux, Denis

2016-01-01

Highlights: • Flavanol-macromolecule interactions were determined using SPR. • Flavanols were chemically modified with a linker bearing a thiol group. • Flavanols were immobilized onto a carboxymethyl dextran surface. • Citrus pectin interacted more with flavanols than apple pectin. • Epicatechin interacted more with BSA than flavanol oligomer. - Abstract: Interactions between plant polyphenols and biomacromolecules such as proteins and pectins have been studied by several methods in solution (e.g. isothermal titration calorimetry, dynamic light scattering, nuclear magnetic resonance and spectrophotometry). Herein, these interactions were investigated in real time by Surface Plasmon Resonance (SPR) analysis after immobilization of flavan-3-ols onto a sensor chip surface. (−)-epicatechin, (+)-catechin and flavan-3-ol oligomers with an average degree of polymerization of 2 and 8 were chemically modified using N-(2-(tritylthio)ethyl)propiolamide in order to introduce a spacer unit onto the catecholic B ring. Modified flavan-3-ols were then immobilized onto a carboxymethylated dextran surface (CM5). Immobilization was validated and further verified by evaluating flavan-3-ol interaction with bovine serum albumin (BSA), poly-L-proline or commercial pectins. BSA was found to have a stronger association with monomeric flavan-3-ols than oligomers. SPR analysis of selected flavan-3-ols immobilized onto CM5 sensor chips showed a stronger association for citrus pectins than apple pectins, regardless of flavan-3-ol degree of polymerization.

An Advanced Semimetal-Organic Bi Spheres-g-C3N4 Nanohybrid with SPR-Enhanced Visible-Light Photocatalytic Performance for NO Purification.

Science.gov (United States)

Dong, Fan; Zhao, Zaiwang; Sun, Yanjuan; Zhang, Yuxin; Yan, Shuai; Wu, Zhongbiao

2015-10-20

To achieve efficient photocatalytic air purification, we constructed an advanced semimetal-organic Bi spheres-g-C3N4 nanohybrid through the in-situ growth of Bi nanospheres on g-C3N4 nanosheets. This Bi-g-C3N4 compound exhibited an exceptionally high and stable visible-light photocatalytic performance for NO removal due to the surface plasmon resonance (SPR) endowed by Bi metal. The SPR property of Bi could conspicuously enhance the visible-light harvesting and the charge separation. The electromagnetic field distribution of Bi spheres involving SPR effect was simulated and reaches its maximum in close proximity to the Bi particle surface. When the Bi metal content was controlled at 25%, the corresponding Bi-g-C3N4 displayed outstanding photocatalytic capability and transcended those of other visible-light photocatalysts. The Bi-g-C3N4 exhibited a high structural stability under repeated photocatalytic runs. A new visible-light-induced SPR-based photocatalysis mechanism with Bi-g-C3N4 was proposed on the basis of the DMPO-ESR spin-trapping. The photoinduced electrons could transfer from g-C3N4 to the Bi metal, as revealed with time-resolved fluorescence spectra. The function of Bi semimetal as a plasmonic cocatalyst for boosting visible light photocatalysis was similar to that of noble metals, which demonstrated a great potential of utilizing the economically feasible Bi element as a substitute for noble metals for the advancement of photocatalysis efficiency.

Grating-Coupled Surface Plasmon Resonance (GC-SPR) Optimization for Phase-Interrogation Biosensing in a Microfluidic Chamber.

Science.gov (United States)

Rossi, Stefano; Gazzola, Enrico; Capaldo, Pietro; Borile, Giulia; Romanato, Filippo

2018-05-18

Surface Plasmon Resonance (SPR)-based sensors have the advantage of being label-free, enzyme-free and real-time. However, their spreading in multidisciplinary research is still mostly limited to prism-coupled devices. Plasmonic gratings, combined with a simple and cost-effective instrumentation, have been poorly developed compared to prism-coupled system mainly due to their lower sensitivity. Here we describe the optimization and signal enhancement of a sensing platform based on phase-interrogation method, which entails the exploitation of a nanostructured sensor. This technique is particularly suitable for integration of the plasmonic sensor in a lab-on-a-chip platform and can be used in a microfluidic chamber to ease the sensing procedures and limit the injected volume. The careful optimization of most suitable experimental parameters by numerical simulations leads to a 30⁻50% enhancement of SPR response, opening new possibilities for applications in the biomedical research field while maintaining the ease and versatility of the configuration.

Development of low cost and accurate homemade sensor system based on Surface Plasmon Resonance (SPR)

Science.gov (United States)

Laksono, F. D.; Supardianningsih; Arifin, M.; Abraha, K.

2018-04-01

In this paper, we developed homemade and computerized sensor system based on Surface Plasmon Resonance (SPR). The developed systems consist of mechanical system instrument, laser power sensor, and user interface. The mechanical system development that uses anti-backlash gear design was successfully able to enhance the angular resolution angle of incidence laser up to 0.01°. In this system, the laser detector acquisition system and stepper motor controller utilizing Arduino Uno which is easy to program, flexible, and low cost, was used. Furthermore, we employed LabView’s user interface as the virtual instrument for facilitating the sample measurement and for transforming the data recording directly into the digital form. The test results using gold-deposited half-cylinder prism showed the Total Internal Reflection (TIR) angle of 41,34°± 0,01° and SPR angle of 44,20°± 0,01°, respectively. The result demonstrated that the developed system managed to reduce the measurement duration and data recording errors caused by human error. Also, the test results also concluded that the system’s measurement is repeatable and accurate.

Grating coupled SPR microarray analysis of proteins and cells in blood from mice with breast cancer.

Science.gov (United States)

Mendoza, A; Torrisi, D M; Sell, S; Cady, N C; Lawrence, D A

2016-01-21

Biomarker discovery for early disease diagnosis is highly important. Of late, much effort has been made to analyze complex biological fluids in an effort to develop new markers specific for different cancer types. Recent advancements in label-free technologies such as surface plasmon resonance (SPR)-based biosensors have shown promise as a diagnostic tool since there is no need for labeling or separation of cells. Furthermore, SPR can provide rapid, real-time detection of antigens from biological samples since SPR is highly sensitive to changes in surface-associated molecular and cellular interactions. Herein, we report a lab-on-a-chip microarray biosensor that utilizes grating-coupled surface plasmon resonance (GCSPR) and grating-coupled surface plasmon coupled fluorescence (GCSPCF) imaging to detect circulating tumor cells (CTCs) from a mouse model (FVB-MMTV-PyVT). GCSPR and GCSPCF analysis was accomplished by spotting antibodies to surface cell markers, cytokines and stress proteins on a nanofabricated GCSPR microchip and screening blood samples from FVB control mice or FVB-MMTV-PyVT mice with developing mammary carcinomas. A transgenic MMTV-PyVT mouse derived cancer cell line was also analyzed. The analyses indicated that CD24, CD44, CD326, CD133 and CD49b were expressed in both cell lines and in blood from MMTV-PyVT mice. Furthermore, cytokines such as IL-6, IL-10 and TNF-α, along with heat shock proteins HSP60, HSP27, HSc70(HSP73), HSP90 total, HSP70/HSc70, HSP90, HSP70, HSP90 alpha, phosphotyrosine and HSF-1 were overexpressed in MMTV-PyVT mice.

Fast and sensitive detection of ochratoxin A in red wine by nanoparticle-enhanced SPR.

Science.gov (United States)

Karczmarczyk, Aleksandra; Reiner-Rozman, Ciril; Hageneder, Simone; Dubiak-Szepietowska, Monika; Dostálek, Jakub; Feller, Karl-Heinz

2016-09-21

Herein, we present a fast and sensitive biosensor for detection of Ochratoxin A (OTA) in a red wine that utilizes gold nanoparticle-enhanced surface plasmon resonance (SPR). By combining an indirect competitive inhibition immunoassay and signal enhancement by secondary antibodies conjugated with gold nanoparticles (AuNPs), highly sensitive detection of low molecular weight compounds (such as OTA) was achieved. The reported biosensor allowed for OTA detection at concentrations as low as 0.75 ng mL(-1) and its limit of detection was improved by more than one order of magnitude to 0.068 ng mL(-1) by applying AuNPs as a signal enhancer. The study investigates the interplay of size of AuNPs and affinity of recognition elements affecting the efficiency of the signal amplification strategy based on AuNP. Furthermore, we observed that the presence of polyphenolic compounds in wine samples strongly interferes with the affinity binding on the surface. To overcome this limitation, a simple pre-treatment of the wine sample with the binding agent poly(vinylpyrrolidone) (PVP) was successfully applied. Copyright © 2016 Elsevier B.V. All rights reserved.

Approaches to Formation of Technical Reserves of Insurance Organizations: Domestic Realities and International Requirements

Directory of Open Access Journals (Sweden)

Prykaziuk Natalia V.

2017-03-01

Full Text Available he aim of the article is to study approaches to formation of insurance reserves by insurance companies in Ukraine and the world. The essence and peculiarities of the formation of reserves by insurance organizations in Ukraine are investigated. The provisions of the Solvency II Directive in terms of formation of reserves and financial stability in insurance organizations are considered. A comparative characteristic of the requirements for the solvency of insurers in accordance with the legislation of Ukraine and the requirements of Solvency II is presented. Differences in methods of formation of technical reserves by insurance organizations in Ukraine and the world are determined, factors affecting it are indicated. Methods of formation of insurance reserves in the countries of the European Union are considered. The directions of improving the process of formation of insurance reserves of the insurer are justified. The problems of introducing the experience of foreign countries and Solvency II requirements are analyzed taking into account the realities of the domestic insurance market. The strengths and weaknesses of the introduction of Solvency II in the Ukrainian insurance market are explored.

Day-ahead optimal dispatch for wind integrated power system considering zonal reserve requirements

International Nuclear Information System (INIS)

Liu, Fan; Bie, Zhaohong; Liu, Shiyu; Ding, Tao

2017-01-01

Highlights: • Analyzing zonal reserve requirements for wind integrated power system. • Modeling day-ahead optimal dispatch solved by chance constrained programming theory. • Determining optimal zonal reserve demand with minimum confidence interval. • Analyzing numerical results on test and large-scale real-life power systems. - Abstract: Large-scale integration of renewable power presents a great challenge for day-ahead dispatch to manage renewable resources while provide available reserve for system security. Considering zonal reserve is an effective way to ensure reserve deliverability when network congested, a random day-ahead dispatch optimization of wind integrated power system for a least operational cost is modeled including zonal reserve requirements and N − 1 security constraints. The random model is transformed into a deterministic one based on the theory of chance constrained programming and a determination method of optimal zonal reserve demand is proposed using the minimum confidence interval. After solving the deterministic model, the stochastic simulation is conducted to verify the validity of solution. Numerical tests and results on the IEEE 39 bus system and a large-scale real-life power system demonstrate the optimal day-ahead dispatch scheme is available and the proposed method is effective for improving reserve deliverability and reducing load shedding after large-capacity power outage.

Multiplexed imaging surface plasmon resonance (iSPR) biosensor assay for the detection of Fusarium toxins in wheat

Science.gov (United States)

Certain Fusarium species (F. graminearum and F. verticilloides in particular) infest grains and can produce a wide range of fungal (myco)-toxins, causing huge economic losses worldwide. A reproducible and sensitive imaging surface plasmon resonance (iSPR) assay was developed and validated for three ...

Target immobilization as a strategy for NMR-based fragment screening: comparison of TINS, STD, and SPR for fragment hit identification.

Science.gov (United States)

Kobayashi, Masakazu; Retra, Kim; Figaroa, Francis; Hollander, Johan G; Ab, Eiso; Heetebrij, Robert J; Irth, Hubertus; Siegal, Gregg

2010-09-01

Fragment-based drug discovery (FBDD) has become a widely accepted tool that is complementary to high-throughput screening (HTS) in developing small-molecule inhibitors of pharmaceutical targets. Because a fragment campaign can only be as successful as the hit matter found, it is critical that the first stage of the process be optimized. Here the authors compare the 3 most commonly used methods for hit discovery in FBDD: high concentration screening (HCS), solution ligand-observed nuclear magnetic resonance (NMR), and surface plasmon resonance (SPR). They selected the commonly used saturation transfer difference (STD) NMR spectroscopy and the proprietary target immobilized NMR screening (TINS) as representative of the array of possible NMR methods. Using a target typical of FBDD campaigns, the authors find that HCS and TINS are the most sensitive to weak interactions. They also find a good correlation between TINS and STD for tighter binding ligands, but the ability of STD to detect ligands with affinity weaker than 1 mM K(D) is limited. Similarly, they find that SPR detection is most suited to ligands that bind with K(D) better than 1 mM. However, the good correlation between SPR and potency in a bioassay makes this a good method for hit validation and characterization studies.

Reduction of wind power induced reserve requirements by advanced shortest-term forecasts and prediction intervals

Energy Technology Data Exchange (ETDEWEB)

Dobschinski, Jan; Wessel, Arne; Lange, Bernhard; Bremen, Lueder von [Fraunhofer Institut fuer Windenergie und Energiesystemtechnik (IWES), Kassel (Germany)

2009-07-01

In electricity systems with large penetration of wind power, the limited predictability of the wind power generation leads to an increase in reserve and balancing requirements. At first the present study concentrates on the capability of dynamic day-ahead prediction intervals to reduce the wind power induced reserve and balancing requirements. Alternatively the reduction of large forecast errors of the German wind power generation by using advanced shortest-term predictions has been evaluated in a second approach. With focus on the allocation of minute reserve power the aim is to estimate the maximal remaining uncertainty after trading activities on the intraday market. Finally both approaches were used in a case study concerning the reserve requirements induced by the total German wind power expansion in 2007. (orig.)

Cloning, expression and structural stability of a cold-adapted ß-Galactosidase from Rahnella sp.R3

Science.gov (United States)

A novel gene was isolated for the first time from a psychrophilic gram-negative bacterium Rahnella sp.R3. It encoded a cold-adapted ß-galactosidase (R-ß-Gal). Recombinant R-ß-Gal was expressed in Escherichia coli BL21 (DE3), purified, and characterized. R-ß-Gal belongs to the glycosyl hydrolase fami...

SFG and SPR Study of Sodium Dodecyl Sulfate Film Assembly on Positively Charged Surfaces

Science.gov (United States)

Song, Sanghun; Weidner, Tobias; Wagner, Matthew; Castner, David

2012-02-01

This study uses sum frequency generation (SFG) vibrational spectroscopy and surface plasmon resonance (SPR) sensing to investigate the structure of sodium dodecyl sulfate (SDS) films formed on positively charged and hydrophilic surfaces. The SPR signals show a good surface coverage suggesting that full monolayer coverage is reached at 1 mM. SFG spectra of SDS adsorbed exhibits well resolved CH3 peaks and OH peaks. At both 0.2 mM and 1 mM SDS concentration the intensity of both the CH3 and OH peaks decreased close to background levels. We found that the loss of SFG signal at 0.2 mM occurs at this concentration independent of surface charge density. It is more likely that the loss of signal is related to structural inhomogeneity induced by a striped phase - stand-up phase transition. This is supported by a distinct change of the relative SFG phase between CH3/OH near 0.2 mM. The second intensity minimum might be related to charge compensation effects. We observed a substrate dependence for the high concentration transition. We also observed distinct SFG signal phase changes for water molecules associated with SDS layers at different SDS solution concentrations indicating that the orientation of bound water changed with SDS surface structure.

Gold nanoparticles decorated on BaTiO3 as photocatalyst: effect of SPR and ferroelectricity

Science.gov (United States)

Miao, Zhilei; Chen, Lei; Wang, Rui; Yuan, Rongchun; Zhou, Fang; Lv, Pengfei; Zhang, Xiuyun; Wang, Qiang

2018-02-01

BaTiO3(BTO) powders with cubic(C) and tetragonal(T) crystalline structures were prepared by sol-gel method followed by calcination at different temperatures, and they were decorated with gold nanoparticles(AuNPs) to form Au-T-BTO and Au-C-BTO respectively. All the samples (C-BTO, T-BTO, Au-C-BTO and Au-T-BTO) were used as photo-catalysts for the degradation of Rhodamine B (RhB). Au-T-BTO exhibits the highest photocatalytic activity due to thecombined effect of surface plasmon resonance (SPR) and the ferroelectricity of the tetragonalphase BTO. The light absorption peaks at 500 to 600 nm verify the presence of SPR effect from Au NPs. Based on density functional theory (DFC) within the generalized gradient approximation (GGA) approach, it was demonstrated that the tetragonal phase BaTiO3 shows a spontaneous polarization with the calculated value of 0.34 C m-2, which is absent in thecubic phase. The internal space charge layer in tetragonal phase BTO enhances the separation of photoexcited carriers due to the spontaneous ferroelectric polarization, which also benefits photocatalytic activities.

Synthesis of surface plasmon resonance (SPR) triggered Ag/TiO2 photocatalyst for degradation of endocrine disturbing compounds

International Nuclear Information System (INIS)

Leong, Kah Hon; Gan, Bee Ling; Ibrahim, Shaliza; Saravanan, Pichiah

2014-01-01

Graphical abstract: - Highlights: • Ag/TiO 2 was synthesized with aid of natural photon stimulated photoreduction. • Deposited Ag prompted well the LSPRs, Schottky barrier for visible light utilization. • Photocatalytic activity was evaluated by degrading EDCs under visible light. • 3.0 wt% Ag/TiO 2 resulted with good photocatalytic efficiency over others. - Abstract: Surface deposition of silver nanoparticles (Ag NPs) onto the 100% anatase titania (Ag/TiO 2 ) for evolution of surface plasmon resonance (SPR) was achieved sustainably with the assistance of solar energy. The preparation resulted in Ag/TiO 2 photocatalyst with varied Ag depositions (0.5 wt%, 1.0 wt%, 3.0 wt% and 5.0 wt%). All obtained photocatalysts were characterized for the evolution of SPR via crystalline phase analysis, morphology, lattice fringes, surface area and pore size characteristics, chemical composition with chemical and electronic state, Raman scattering, optical and photoluminescence properties. The deposition of synthesized Ag NPs exhibited high uniformity and homogeneity and laid pathway for effective utilization of the visible region of electromagnetic spectrum through SPR. The depositions also lead for suppressing recombination rates of electron–hole. The photocatalytic evaluation was carried out by adopting two different class of endocrine disturbing compound (EDC) i.e., amoxicillin (pharmaceutical) and 2,4-dichlorophenol (pesticide) excited with artificial visible light source. Ag/TiO 2 with Ag > 0.5 wt% exhibited significant degradation efficiency for both amoxicillin and 2,4-dichlorophenol. Thus synthesized Ag/TiO 2 revealed the implication of plasmonics on TiO 2 for the enhanced visible light photocatalytic activity

Antibody-Hapten Recognition at the Surface of Functionalized Liposomes Studied by SPR: Steric Hindrance of Pegylated Phospholipids in Stealth Liposomes Prepared for Targeted Radionuclide Delivery

Directory of Open Access Journals (Sweden)

Eliot. P. Botosoa

2011-01-01

Full Text Available Targeted PEGylated liposomes could increase the amount of drugs or radionuclides delivered to tumor cells. They show favorable stability and pharmacokinetics, but steric hindrance of the PEG chains can block the binding of the targeting moiety. Here, specific interactions between an antihapten antibody (clone 734, specific for the DTPA-indium complex and DTPA-indium-tagged liposomes were characterized by surface plasmon resonance (SPR. Non-PEGylated liposomes fused on CM5 chips whereas PEGylated liposomes did not. By contrast, both PEGylated and non-PEGylated liposomes attached to L1 chips without fusion. SPR binding kinetics showed that, in the absence of PEG, the antibody binds the hapten at the surface of lipid bilayers with the affinity of the soluble hapten. The incorporation of PEGylated lipids hinders antibody binding to extents depending on PEGylated lipid fraction and PEG molecular weight. SPR on immobilized liposomes thus appears as a useful technique to optimize formulations of liposomes for targeted therapy.

Dynamic SPR monitoring of yeast nuclear protein binding to a cis-regulatory element

International Nuclear Information System (INIS)

Mao, Grace; Brody, James P.

2007-01-01

Gene expression is controlled by protein complexes binding to short specific sequences of DNA, called cis-regulatory elements. Expression of most eukaryotic genes is controlled by dozens of these elements. Comprehensive identification and monitoring of these elements is a major goal of genomics. In pursuit of this goal, we are developing a surface plasmon resonance (SPR) based assay to identify and monitor cis-regulatory elements. To test whether we could reliably monitor protein binding to a regulatory element, we immobilized a 16 bp region of Saccharomyces cerevisiae chromosome 5 onto a gold surface. This 16 bp region of DNA is known to bind several proteins and thought to control expression of the gene RNR1, which varies through the cell cycle. We synchronized yeast cell cultures, and then sampled these cultures at a regular interval. These samples were processed to purify nuclear lysate, which was then exposed to the sensor. We found that nuclear protein binds this particular element of DNA at a significantly higher rate (as compared to unsynchronized cells) during G1 phase. Other time points show levels of DNA-nuclear protein binding similar to the unsynchronized control. We also measured the apparent association complex of the binding to be 0.014 s -1 . We conclude that (1) SPR-based assays can monitor DNA-nuclear protein binding and that (2) for this particular cis-regulatory element, maximum DNA-nuclear protein binding occurs during G1 phase

Joining of polymer-metal lightweight structures using self-piercing riveting (SPR) technique: Numerical approach and simulation results

Science.gov (United States)

Amro, Elias; Kouadri-Henni, Afia

2018-05-01

Restrictions in pollutant emissions dictated at the European Commission level in the past few years have urged mass production car manufacturers to engage rapidly several strategies in order to reduce significantly the energy consumption of their vehicles. One of the most relevant taken action is light-weighting of body in white (BIW) structures, concretely visible with the increased introduction of polymer-based composite materials reinforced by carbon/glass fibers. However, the design and manufacturing of such "hybrid" structures is limiting the use of conventional assembly techniques like resistance spot welding (RSW) which are not transferable as they are for polymer-metal joining. This research aims at developing a joining technique that would eventually enable the assembly of a sheet molding compound (SMC) polyester thermoset-made component on a structure composed of several high strength steel grades. The state of the art of polymer-metal joining techniques highlighted the few ones potentially able to respond to the industrial challenge, which are: structural bonding, self-piercing riveting (SPR), direct laser joining and friction spot welding (FSpW). In this study, the promising SPR technique is investigated. Modelling of SPR process in the case of polymer-metal joining was performed through the building of a 2D axisymmetric FE model using the commercial code Abaqus CAE 6.10-1. Details of the numerical approach are presented with a particular attention to the composite sheet for which Mori-Tanaka's homogenization method is used in order to estimate overall mechanical properties. Large deformations induced by the riveting process are enabled with the use of a mixed finite element formulation ALE (arbitrary Lagrangian-Eulerian). FE model predictions are compared with experimental data followed by a discussion.

Informační systém pro správu rezervací v restauracích

OpenAIRE

Slanař, David

2009-01-01

Tato bakalářská práce pojednává o stávajícím stavu fungování rezervací v restauracích a jeho inovaci pomocí zavedení informačního systému pro vytváření a správu rezervací. Popisuje návrh internetové webové aplikace umožňující on-line vytváření rezervací samotnými uživateli a jejich následnou správu zaměstnanci. Dále popis ekonomického přínosu a jiných výhod plynoucích ze zavedení tohoto systému v reálném světě a v neposlední řadě řešení případných problémů při nasazování systému v praxi. T...

Environmental Assessment on the leasing of the Strategic Petroleum Reserve, St. James Terminal, St. James Parish, Louisiana

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-01-01

The US Department of Energy (DOE) proposes to lease the Strategic Petroleum Reserve`s (SPR) St. James Terminal to private industry. The St. James Terminal consists of six storage tanks, a pumping station, two maine docks and ancillary facilities. DOE believes that the St. James Terminal presents an opportunity to establish a government- industry arrangement that could more effectively use this asset to serve the nations`s oil distribution needs, reduce the operational cost of the SPR, and provide a source of revenue for the Government. DOE solicited interest in leasing its distribution facilities in a notice published March 16, 1994. In response, industry has expressed interest in leasing the St. James Terminal, as well as several DOE pipelines, to enhance the operation of its own facilities or to avoid having to construct new ones. Under such a lease, industry use would be subordinate to DOE use in the event of a national energy emergency. This Environmental Assessment describes the proposed leasing operation, its alternatives, and potential environmental impacts. Based on this analyses, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) OF 1969 and has issued the Finding of No Significant Impact (FONSI).

Bryan Mound InSAR Analysis U.S. Strategic petroleum Reserve.

Energy Technology Data Exchange (ETDEWEB)

Lord, Anna C. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2017-06-01

The U.S. Strategic Petroleum Reserve (SPR) is a stockpile of emergency crude oil to be tapped into if a disruption in the nation's oil supply occurs. The SPR is comprised of four salt dome sites. Subsidence surveys have been conducted either annually or biennially at all four sites over the life of the program. Monitoring of surface behavior is a first line defense to detecting possible subsurface cavern integrity issues. Over the life of the Bryan Mound site, subsidence rates over abandoned Cavern 3 have continuously been the highest at the site. In an effort to try and understand the subsurface dynamics, specifically over Bryan Mound Cavern 3, historic interferometric synthetic aperture radar (InSAR) data was acquired and processed by TRE Altamira. InSAR involves the processing of multiple satellite synthetic aperture radar scenes acquired across the same location of the Earth's surface at different times to map surface deformation. The analysis of the data has the ability to detect millimeters of motion spanning days, months, year and decades, across specific sites. The intent in regards to the Bryan Mound site was (1) to confirm the higher subsidence rates recorded over abandoned Cavern 3 indicated by land survey and (2) understand the regional surface behavior. This report describes the InSAR analysis results, how those results compare to the historical collection of land survey data, and what additional information the data has provided towards understanding the response recorded at the surface.

Comparative study of SPR and ELISA methods based on analysis of CD166/ALCAM levels in cancer and control human sera

Czech Academy of Sciences Publication Activity Database

Vaisocherová, Hana; Faca, V.M.; Taylor, A. D.; Hanash, S.; Jiang, S.

2009-01-01

Roč. 24, č. 7 (2009), s. 2143-2148 ISSN 0956-5663 Institutional research plan: CEZ:AV0Z20670512 Keywords : SPR * ELISA * Cancer biomarkers Subject RIV: CE - Biochemistry Impact factor: 5.429, year: 2009

Plasma processing of the Si(0 0 1) surface for tuning SPR of Au/Si-based plasmonic nanostructures

Energy Technology Data Exchange (ETDEWEB)

Giangregorio, Maria M. [Institute of Inorganic Methodologies and of Plasmas, IMIP-CNR and INSTM sez. Bari, Via Orabona 4, 70125 Bari (Italy)]. E-mail: michelaria.giangregorio@ba.imip.cnr.it; Losurdo, Maria [Institute of Inorganic Methodologies and of Plasmas, IMIP-CNR and INSTM sez. Bari, Via Orabona 4, 70125 Bari (Italy); Sacchetti, Alberto [Institute of Inorganic Methodologies and of Plasmas, IMIP-CNR and INSTM sez. Bari, Via Orabona 4, 70125 Bari (Italy); Capezzuto, Pio [Institute of Inorganic Methodologies and of Plasmas, IMIP-CNR and INSTM sez. Bari, Via Orabona 4, 70125 Bari (Italy); Bruno, Giovanni [Institute of Inorganic Methodologies and of Plasmas, IMIP-CNR and INSTM sez. Bari, Via Orabona 4, 70125 Bari (Italy)

2006-12-15

Au nanoclusters have been deposited on Si(0 0 1) surfaces by sputtering of a metallic Au target using an Ar plasma. Different wet and dry treatments of the Si(0 0 1) surface, including dipping in HF solution and exposure to H{sub 2} and N{sub 2} plasmas, have been applied and the effects of these treatments on the Au nanoparticles/Si interface, the Au nanoclusters aspect ratio and the surface plasmon resonance (SPR) energy and amplitude are investigated exploiting spectroscopic ellipsometry and atomic force microscopy. It is found that the Au nanoclusters aspect ratio depends on the extent of the Au-Si intermixing. The thicker the Au-Si interface layer, the larger the Au nanoparticles aspect ratio and the red-shift of the SPR peak. Furthermore, SiO{sub 2} and the H{sub 2} plasma treatment inhibit the Si-Au intermixing, while HF-dipping and the N{sub 2} plasma treatment favour Au-Si intermixing, yielding silicide formation which increases the Si wetting by Au.

17 CFR 270.27d-1 - Reserve requirements for principal underwriters and depositors to carry out the obligations to...

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Reserve requirements for....27d-1 Reserve requirements for principal underwriters and depositors to carry out the obligations to... reserve and as security for the purpose of assuring the refund of charges required by sections 27(d) and...

Thailand's energy security: Strategic Petroleum Reserve and its economic impacts

Science.gov (United States)

Leesombatpiboon, Poonpat

This dissertation studies Thailand's energy security from three related perspectives, the role of oil on the Thai macroeconomy, the sectoral demand for oil in Thailand, and the Strategic Petroleum Reserve (SPR) policy for the Thai economy. The first part of my dissertation estimates an error correction model of aggregate production function for Thailand. Thai economic growth is modeled as a function of labor, capital, and oil consumption. Unlike previous studies that focus on testing the causal relationship between energy consumption and economic growth, I focus on measuring the elasticity of economic growth with respect to oil consumption and oil prices. I find a cointegration relationship between GDP, capital, labor, and oil consumption. The results suggest that there exists a constant-return-to-scale characteristic in Thailand's aggregate production function with the contribution of labor, oil, and capital to output around 68, 19, and 13 percent respectively. The long-run and short-run contribution of oil consumption to the economy appears to be fairly close, suggesting that oil has a critical role in the Thai economy. In the short run, oil shortages have a much more severe impact on Thai economy than the effects of an oil price shock. For example, a 10 percent shortfall in oil consumption might cause economic growth to shrink by 2 percent within the same year while a sharp10 percent rise in oil prices canlead output growth to a fall by about 0.5 percent. The response of output to increases and decreases in oil prices is found to be asymmetric in the short run. The second part of my dissertation examines the short-run and long-run determinants of final oil consumption in seven major economic sectors in Thailand. Two different approaches are compared. The first approach uses dynamic panel data estimation techniques taking into account oil consumption of the whole economy in an aggregate manner. The second approach employs the Autoregressive Distributed Lag (ADL

Geologic technical assessment of the Stratton Ridge salt dome, Texas, for potential expansion of the U.S. strategic petroleum reserve.

Energy Technology Data Exchange (ETDEWEB)

Rautman, Christopher Arthur; Snider, Anna C.; Looff, Karl M. (Geologic Consultant, Lovelady, TX)

2006-11-01

The Stratton Ridge salt dome is a large salt diapir located only some ten miles from the currently active Strategic Petroleum Reserve Site at Bryan Mound, Texas. The dome is approximately 15 miles south-southwest of Houston. The Stratton Ridge salt dome has been intensively developed, in the desirable central portions, with caverns for both brine production and product storage. This geologic technical assessment indicates that the Stratton Ridge salt dome may be considered a viable, if less-than-desirable, candidate site for potential expansion of the Strategic Petroleum Reserve (SPR). Past development of underground caverns significantly limits the potential options for use by the SPR. The current conceptual design layout of proposed caverns for such an expansion facility is based upon a decades-old model of salt geometry, and it is unacceptable, according to this reinterpretation of salt dome geology. The easternmost set of conceptual caverns are located within a 300-ft buffer zone of a very major boundary shear zone, fault, or other structural feature of indeterminate origin. This structure transects the salt stock and subdivides it into an shallow western part and a deeper eastern part. In places, the distance from this structural boundary to the design-basis caverns is as little as 150 ft. A 300-ft distance from this boundary is likely to be the minimum acceptable stand-off, from both a geologic and a regulatory perspective. Repositioning of the proposed cavern field is possible, as sufficient currently undeveloped salt acreage appears to be available. However, such reconfiguration would be subject to limitations related to land-parcel boundaries and other existing infrastructure and topographic constraints. More broadly speaking, the past history of cavern operations at the Stratton Ridge salt dome indicates that operation of potential SPR expansion caverns at this site may be difficult, and correspondingly expensive. Although detailed information is

Analysis of cavern stability at the Bryan Mound SPR site.

Energy Technology Data Exchange (ETDEWEB)

Ehgartner, Brian L.; Sobolik, Steven Ronald

2009-04-01

This report presents computational analyses that simulate the structural response of caverns at the Strategic Petroleum Reserve Bryan Mound site. The cavern field comprises 20 caverns. Five caverns (1, 2, 4, and 5; 3 was later plugged and abandoned) were acquired from industry and have unusual shapes and a history dating back to 1946. The other 16 caverns (101-116) were leached according to SPR standards in the mid-1980s and have tall cylindrical shapes. The history of the caverns and their shapes are simulated in a 3-D geomechanics model of the site that predicts deformations, strains, and stresses. Future leaching scenarios due to oil drawdowns using fresh water are also simulated by increasing the volume of the caverns. Cavern pressures are varied in the model to capture operational practices in the field. The results of the finite element model are interpreted to provide information on the current and future status of subsidence, well integrity, and cavern stability. The most significant result in this report is relevant to caverns 1, 2, and 5. The caverns have non-cylindrical shapes and have potential regions where the surrounding salt may be damaged during workover procedures. During a workover the normal cavern operating pressure is lowered to service a well. At this point the wellhead pressures are atmospheric. When the workover is complete, the cavern is repressurized. The resulting elastic stresses are sufficient to cause tension and large deviatoric stresses at several locations. With time, these stresses relax to a compressive state due to salt creep. However, the potential for salt damage and fracturing exists. The analyses predict tensile stresses at locations with sharp-edges in the wall geometry, or in the case of cavern 5, in the neck region between the upper and lower lobes of the cavern. The effects do not appear to be large-scale, however, so the only major impact is the potential for stress-induced salt falls in cavern 5, potentially leading to

Determining reserve requirements in DK1 area of Nord Pool using a probabilistic approach

DEFF Research Database (Denmark)

Saez Gallego, Javier; Morales González, Juan Miguel; Madsen, Henrik

2014-01-01

a probabilistic framework where the reserve requirements are computed based on scenarios of wind power forecast error, load forecast errors and power plant outages. Our approach is first motivated by the increasing wind power penetration in power systems worldwide as well as the current market design of the DK1...... System Operator). © 2014 Elsevier Ltd. All rights reserved....

Sambandet mellan Theory of Mind, språkliga förmågor och exekutiva funktioner hos barn i treårsåldern

OpenAIRE

Nilsson, Anna; Sirén, Ellen

2015-01-01

Barns fem första levnadsår präglas av en omfattande utveckling av språkliga förmågor och exekutiva funktioner, vilka är färdigheter som visat sig ha en stor påverkan på hur barn utvecklar förståelse för sina egna och andras tankar, det vill säga deras Theory of Mind. En central aspekt inom forskning har varit att undersöka hur förmågorna samvarierar vid olika åldrar. Syftet i föreliggande studie var att undersöka sambandet mellan Theory of Mind, språkliga förmågor och exekutiva funktioner hos...

Reforma veřejné správy: analýza Strategie realizace Smart Administration

OpenAIRE

Hurychová, Tereza

2016-01-01

This diploma thesis is mainly to explain the significance of the document Efektivní veřejná správa a přátelské služby: Strategie realizace Smart Administration 2007 - 2015 2015 (Efficient public administration and friendly service: Smart Administration Strategy 2007 - 2015) in the context of the reform process of public administration in the Czech republic. The author′s point of view is based of the theory of change, strategic managment and modern managment methods in public administration. A...

Real-time monitoring of mycobacterium genomic DNA with target-primed rolling circle amplification by a Au nanoparticle-embedded SPR biosensor.

Science.gov (United States)

Xiang, Yang; Zhu, Xiaoyan; Huang, Qing; Zheng, Junsong; Fu, Weiling

2015-04-15

In this study, we developed a surface plasmon resonance (SPR) DNA biosensor array based on target-primed rolling circle amplification (RCA) for isothermal and rapid detection of two pathogenic mycobacteria, Mycobacterium tuberculosis complex (MTBC) and Mycobacterium avium complex (MAC).The species-specific padlock probe (PLP) was designed to target the sequence in 16S-23S rRNA gene internal transcribed spacer (ITS). After ligation, the circularized PLP could be primed by the target sequence to initial RCA. The RCA performed simultaneously with the cleavage reaction to produce small fragments of single strand DNA which immediately hybridized with the probe immobilized on the sensor chip without denaturation. This process caused SPR angle changes on the chip surface, which made the detection for analysis from the solution achievable, and dynamic real-time RCA monitoring of mycobacterium possible. Besides, Au nanoparticles (AuNPs) were directly assembled onto the surface of the sensor chip via hexanedithiol (HDT) for the enhancement of sensitivity as a label-free detection system. Experimental results show that the signal enhancement by the target-primed RCA together with AuNPs-embedded surface caused at least10-fold increased sensitivity as compared with conventional RCA on bare SPR chip method. Within 40min amplification duration as low as 20amol of synthetic targets and 10(4)CFUmL(-1) of genomic DNA from clinical samples can be detected. The proposed method not only provides a simple design idea for liquid-phase amplification monitoring, but also apply it in clinical pathogen detection, which holds great promise in ultrasensitive bioassay in the future. Copyright © 2014. Published by Elsevier B.V.

Power system reliability impacts of wind generation and operational reserve requirements

Directory of Open Access Journals (Sweden)

Esteban Gil

2015-06-01

Full Text Available Due to its variability, wind generation integration presents a significant challenge to power system operators in order to maintain adequate reliability levels while ensuring least cost operation. This paper explores the trade-off between the benefits associated to a higher wind penetration and the additional operational reserve requirements that they impose. Such exploration is valued in terms of its effect on power system reliability, measured as an amount of unserved energy. The paper also focuses on how changing the Value of Lost Load (VoLL can be used to attain different reliability targets, and how wind power penetration and the diversity of the wind energy resource will impact quality of supply (in terms of instances of unserved energy. The evaluation of different penetrations of wind power generation, different wind speed profiles, wind resource diversity, and different operational reserve requirements, is conducted on the Chilean Northern Interconnected System (SING using statistical modeling of wind speed time series and computer simulation through a 24-hour ahead unit commitment algorithm and a Monte Carlo simulation scheme. Results for the SING suggest that while wind generation can significantly reduce generation costs, it can also imply higher security costs to reach acceptable reliability levels.

SPR Characteristics Curve and Distribution of Residual Stress in Self-Piercing Riveted Joints of Steel Sheets

OpenAIRE

Haque, Rezwanul; Wong, Yat C.; Paradowska, Anna; Blacket, Stuart; Durandet, Yvonne

2017-01-01

Neutron diffraction was used to describe the residual stress distributions in self-piercing riveted (SPR) joints. The sheet material displayed a compressive residual stress near the joint, and the stress gradually became tensile in the sheet material far away from the joint. The stress in the rivet leg was lower in the thick joint of the softer steel sheet than in the thin joint of the harder steel sheet. This lower magnitude was attributed to the lower force gradient during the rivet flaring...

7 CFR 985.57 - Reserve pool requirements.

Science.gov (United States)

2010-01-01

... shall be paid by the equity holders. The proceeds from the disposition of reserve oil shall be... HANDLING OF SPEARMINT OIL PRODUCED IN THE FAR WEST Order Regulating Handling Volume Limitations § 985.57... the Secretary may establish, the Committee shall pool identified excess oil as reserve oil in such...

West Hackberry Strategic Petroleum Reserve site brine-disposal monitoring, year 1 report. Volume 1. Executive summary. Final report

Energy Technology Data Exchange (ETDEWEB)

DeRouen, L.R.; Hann, R.W.; Casserly, D.M.; Giammona, C.; Lascara, V.J. (eds.)

1983-02-01

The physical, chemical and biological attributes are described for: (1) a coastal marine environment centered about a Department of Energy Strategic Petroleum Reserve (SPR) brine disposal site located 11.4 km off the southwest coast of Louisiana; and (2) the lower Calcasieu and Sabine estuarine systems that provide leach waters for the SPR project. During the study period, the daily discharge averaged 529,000 barrels of 216 0/00 brine, representing a loading of 18,000 metric tons of salt per day. The objective of this study are: (1) characterize the environment in terms of physical, chemical and biological attributes; (2) determine if significant adverse changes in ecosystem productivity and stability of the biological community are occurring as a result of brine discharge; and (3) determine the magnitude of any change observed. This report describes the methodology and significant results of the first year's monitoring effort of the West Hackberry brine disposal site. The investigative tasks, presented as separate sections, are: Physical Oceanography, Estuarine Hydrology and Hydrography, Analysis of Discharge Plume, Water and Sediment Quality, Special Pollutant Surveys, Benthos, Nekton, Phytoplankton, Zooplankton and Data Management.

Screening and analysis of beyond design basis accident of 49-2 SPR

International Nuclear Information System (INIS)

Zhang Yadong; Guo Yue; Wu Yuanyuan; Zou Yao

2015-01-01

The beyond design basis accident was analyzed to ensure safe operation of 49-2 Swimming Pool Reactor (SPR) after design life. Because it's difficult to use PSA method, the unconditional assumed severe accidents were adopted to obtain a conservative result. The main conclusions were obtained by analyzing anticipated transients without scram in station blackout (SBO ATWS), horizontal channel rupture, core uncovering after shutdown and emergency response capacity. The results show that the core is safe in SBO ATWS, and the fuel elements will not melt as long as the core are not exposed in 2.5 h in loss of coolant accident caused by horizontal channel rupture and other factors. The passive siphon breaker function and various ways of emergency core makeup can ensure that the core is not exposed. (authors)

Preparation and characterization of thin organosilicon films deposited on SPR chip

Energy Technology Data Exchange (ETDEWEB)

Szunerits, Sabine [Laboratoire d' Electrochimie et de Physicochimie des Materiaux et des Interfaces (LEPMI), CNRS-INPG-UJF, 1130 rue de la piscine, BP 75, 38402 St. Martin d' Heres Cedex (France)], E-mail: sabine.szunerits@lepmi.inpg.fr; Rich, Sami Abou [Laboratoire de Genie des Procedes d' Interaction de Fluides Reactifs-Materiaux U.S.T.L., Cite Scientifique, 59655 Villeneuve d' Ascq (France); Coffinier, Yannick [Institut de Recherche Interdisciplinaire (IRI), FRE CNRS 2963, Institut d' lectronique, de Microelectronique et de Nanotechnologie (IEMN), UMR CNRS-8520, Cite Scientifique, Avenue Poincare, BP 60069, 59652 Villeneuve d' Ascq (France); Languille, Marie-Angelique [Unite de Catalyse et de Chimie du Solide, UCCS UMR CNRS-8181, Universite des Sciences et Technologies de Lille, Bat. C3, 59655 Villeneuve d' Ascq (France); Supiot, Philippe [Laboratoire de Genie des Procedes d' Interaction de Fluides Reactifs-Materiaux U.S.T.L., Cite Scientifique, 59655 Villeneuve d' Ascq (France); Boukherroub, Rabah [Institut de Recherche Interdisciplinaire (IRI), FRE CNRS 2963, Institut d' lectronique, de Microelectronique et de Nanotechnologie (IEMN), UMR CNRS-8520, Cite Scientifique, Avenue Poincare, BP 60069, 59652 Villeneuve d' Ascq (France)], E-mail: rabah.boukherroub@iemn.univ-lille1.fr

2008-04-20

The paper reports on the preparation and characterization of organosilicon thin polymer films deposited on glass slides coated with 5 nm adhesion layer of titanium and 50 nm of gold. The polymer was obtained by the decomposition of 1,1,3,3-tetramethyldisiloxane precursor (TMDSO) premixed with oxygen induced in a N{sub 2} plasma afterglow using remote plasma-enhanced chemical vapor deposition (PECVD) technique. The film thickness was controlled by laser interferometry and was 9 nm. The chemical stability of the gold substrate coated with the organosilicon polymer film (p-TMDSO) was studied in different acidic and basic solutions (pH 1-14). While the gold/polymer interface showed a high stability in acidic media, the film was almost completely removed in basic solutions. The resulting surfaces were characterized using atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS), water contact angle measurements, cyclic voltammetry, and surface plasmon resonance (SPR)

Preparation and characterization of thin organosilicon films deposited on SPR chip

International Nuclear Information System (INIS)

Szunerits, Sabine; Rich, Sami Abou; Coffinier, Yannick; Languille, Marie-Angelique; Supiot, Philippe; Boukherroub, Rabah

2008-01-01

The paper reports on the preparation and characterization of organosilicon thin polymer films deposited on glass slides coated with 5 nm adhesion layer of titanium and 50 nm of gold. The polymer was obtained by the decomposition of 1,1,3,3-tetramethyldisiloxane precursor (TMDSO) premixed with oxygen induced in a N 2 plasma afterglow using remote plasma-enhanced chemical vapor deposition (PECVD) technique. The film thickness was controlled by laser interferometry and was 9 nm. The chemical stability of the gold substrate coated with the organosilicon polymer film (p-TMDSO) was studied in different acidic and basic solutions (pH 1-14). While the gold/polymer interface showed a high stability in acidic media, the film was almost completely removed in basic solutions. The resulting surfaces were characterized using atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS), water contact angle measurements, cyclic voltammetry, and surface plasmon resonance (SPR)

Analysis of cavern and well stability at the West Hackberry SPR site using a full-dome model.

Energy Technology Data Exchange (ETDEWEB)

Sobolik, Steven R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2015-08-01

This report presents computational analyses that simulate the structural response of caverns at the Strategic Petroleum Reserve (SPR) West Hackberry site. The cavern field comprises 22 caverns. Five caverns (6, 7, 8, 9, 11) were acquired from industry and have unusual shapes and a history dating back to 1946. The other 17 caverns (101-117) were leached according to SPR standards in the mid-1980s and have tall cylindrical shapes. The history of the caverns and their shapes are simulated in a three-dimensional geomechanics model of the site that predicts deformations, strains, and stresses. Future leaching scenarios corresponding to oil drawdowns using fresh water are also simulated by increasing the volume of the caverns. Cavern pressures are varied in the model to capture operational practices in the field. The results of the finite element model are interpreted to provide information on the current and future status of subsidence, well integrity, and cavern stability. The most significant results in this report are relevant to Cavern 6. The cavern is shaped like a bowl with a large ceiling span and is in close proximity to Cavern 9. The analyses predict tensile stresses at the edge of the ceiling during repressurization of Cavern 6 following workover conditions. During a workover the cavern is at low pressure to service a well. The wellhead pressures are atmospheric. When the workover is complete, the cavern is repressurized. The resulting elastic stresses are sufficient to cause tension around the edge of the large ceiling span. With time, these stresses relax to a compressive state because of salt creep. However, the potential for salt fracture and propagation exists, particularly towards Cavern 9. With only 200 feet of salt between the caverns, the operational consequences must be examined if the two caverns become connected. A critical time may be during a workover of Cavern 9 in part because of the operational vulnerabilities, but also because dilatant damage

Results of the Weeks Island Strategic Petroleum Reserve Oil Leak Risk Assessment Study

International Nuclear Information System (INIS)

Molecke, M.A.; Hinkebein, T.E.; Bauer, S.J.; Linn, J.K.

1998-12-01

This study evaluated multiple, long-term environmental oil-contamination risk scenarios that could result from the potential leakage of UP to 1.5 million barrels of crude oil entombed in the Weeks Island SPR mine following site decommissioning and abandonment, and up to 100 years thereafter. This risk assessment also provides continuity with similar risk evaluations performed earlier and documented in the 1995 DOE Environmental Assessment for Decommissioning the Strategic Petroleum Reserve Weeks Island Facility (EA). This current study was requested by the DOE to help them determine if their previous Finding of No Significant Impact (FONSI), in the EA, is still valid or needs to be rescinded. Based on the calculated environmental risk results (in terms of clean-up and remediation expenses) presented in this risk assessment, including the calculated average likelihoods of oil release and potential oil-leakage volumes, none of the evaluated risk events would appear to satisfy the definition of significant environmental impact in National Environmental Policy Act (NEPA) terminology. The DOE may combine these current results with their earlier evaluations and interpretations in the 1995 EA in order to assess whether the existing FONSI is still accurate, acceptable, and valid. However, from a risk evaluation standpoint, the assessment of impacts appears to be the same whether only 10,000 to 30,000 barrels of crude oil (as considered in the 1995 EA), or up to 1.5 million barrels of oil (as considered herein) are abandoned in the Weeks Island SPR facility

Stockpile strategy for China's emergency oil reserve: A dynamic programming approach

International Nuclear Information System (INIS)

Bai, Y.; Dahl, C.A.; Zhou, D.Q.; Zhou, P.

2014-01-01

China is currently accelerating construction of its strategic petroleum reserves. How should China fill the SPR in a cost-effective manner in the short-run? How might this affect world oil prices? Using a dynamic programming model to answer these questions, the objective of this paper is to minimize the stockpiling costs, including consumer surplus as well as crude acquisition and holding costs. The crude oil acquisition price in the model is determined by global equilibrium between supply and demand. Demand, in turn, depends on world market conditions including China's stockpile filling rate. Our empirical study under different market conditions shows that China's optimal stockpile acquisition rate varies from 9 to 19 million barrels per month, and the optimal stockpiling drives up the world oil price by 3–7%. The endogenous price increase accounts for 52% of total stockpiling costs in the base case. When the market is tighter or the demand function is more inelastic, the stockpiling affects the market more significantly and pushes prices even higher. Alternatively, in a disruption, drawdown from the stockpile can effectively dampen soaring prices, though the shortage is likely to leave the price higher than before the disruption. - Highlights: • China's SPR policies are examined by dynamic programming. • The optimal stockpile acquisition rate varies from 9 to 19 million barrels per month. • The optimal stockpiling drives up world oil price by 3–7%

Assaying Auxin Receptor Activity Using SPR Assays with F-Box Proteins and Aux/IAA Degrons.

Science.gov (United States)

Quareshy, Mussa; Uzunova, Veselina; Prusinska, Justyna M; Napier, Richard M

2017-01-01

The identification of TIR1 as an auxin receptor combined with advanced biophysical instrumentation has led to the development of real-time activity assays for auxins. Traditionally, molecules have been assessed for auxinic activity using bioassays, and agrochemical compound discovery continues to be based on "spray and pray" technologies. Here, we describe the methodology behind an SPR-based assay that uses TIR1 and related F-box proteins with surface plasmon resonance spectrometry for rapid compound screening. In addition, methods for collecting kinetic binding data and data processing are given so that they may support programs for rational design of novel auxin ligands.

SPR sensors for monitoring the degradation processes of Eu(dbm)3(phen) and Alq3 thin films under atmospheric and UVA exposure

Science.gov (United States)

Del Rosso, T.; Zaman, Q.; Cremona, M.; Pandoli, O.; Barreto, A. R. J.

2018-06-01

The degradation processes of tris(8-hydroxyquinoline) (Alq3) and tris(dibenzoylmethane) mono(1,10-phenanthroline)europium(III) (Eu(dbm)3(phen)) thin films are investigated by the use of AFM, photoluminescence and SPR spectroscopy. The plasmonic sensors are operated both in air and nitrogen environments, where they are irradiated with controlled doses of UVA radiation. AFM results don't reveal the formation of heterogeneous phases and crystallization under air exposure. The organic thin films change their refractive index under both types of exposure and act as a protective layer against oxidation for the SiO2/MPTS/metal interface of the plasmonic sensors. SPR measurements reveal a strict correlation between the refractive index increase and quenching of the photoluminescence of the organic thin films. The results are promising for the development of compact plasmonic UVA dosimeters in the surface plasmon coupled emission configuration (SPCE) with lanthanide β-diketonate complex materials (patent pending).

Legal Reserve Requirements in Brazilian Forests: Path Dependent Evolution of De Facto Legislation

OpenAIRE

Lee J. Alston; Bernardo Mueller

2007-01-01

Why would a poor and largely pro-developmental country such as Brazil, that has so much of its territory covered in forest, adopt one of the most restrictive land use requirements in the world when it comes to cutting the forest to give way to other economic uses? We describe the evolution of legal reserve legislation in Brazil, which currently requires that 20% of the area in a property (80% in the Amazon) be left in forest or its native vegetation. This legislation was put into place in 193...

Environmental Assessment on the leasing of the Strategic Petroleum Reserve, St. James Terminal, St. James Parish, Louisiana

International Nuclear Information System (INIS)

1995-01-01

The US Department of Energy (DOE) proposes to lease the Strategic Petroleum Reserve's (SPR) St. James Terminal to private industry. The St. James Terminal consists of six storage tanks, a pumping station, two maine docks and ancillary facilities. DOE believes that the St. James Terminal presents an opportunity to establish a government- industry arrangement that could more effectively use this asset to serve the nations's oil distribution needs, reduce the operational cost of the SPR, and provide a source of revenue for the Government. DOE solicited interest in leasing its distribution facilities in a notice published March 16, 1994. In response, industry has expressed interest in leasing the St. James Terminal, as well as several DOE pipelines, to enhance the operation of its own facilities or to avoid having to construct new ones. Under such a lease, industry use would be subordinate to DOE use in the event of a national energy emergency. This Environmental Assessment describes the proposed leasing operation, its alternatives, and potential environmental impacts. Based on this analyses, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) OF 1969 and has issued the Finding of No Significant Impact (FONSI)

[Energy requirements in adolescents playing basketball in Russian Olympic reserve team].

Science.gov (United States)

Martinchik, A N; Baturin, A K; Petukhov, A B; Baeva, V S; Zemlianskaia, T A; Sokolov, A I; Peskova, E V; Tysiachnaia, E M

2003-01-01

The energy expenditure and requirements and dietary intake were studied in basketball players aged 14-16 years during 3 week-training period. The subjects of study were 14 boys and 18 girls as of the members of reserve of Russian Olympic basketball team. The dietary intake was estimated by dietary record of all food consumed within 24 hours last 7 days of training period. The energy expenditure was estimated by registration of time on different physical activity of team and multiplication on physical activity coefficient. The decrease of body mass and body mass index were observed in boys with height 195 cm and more to the end of training period. These tall boys did not consume enough food to satisfy the estimated energy requirement. It is estimated that energy need of tall basketball players is no less then 5000 kcal for boys and 3100 kcal for girls.

31 CFR 363.28 - Does Public Debt reserve the right to require that any TreasuryDirect ® transaction be conducted...

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Does Public Debt reserve the right to... Provisions Governing Securities Held in TreasuryDirect § 363.28 Does Public Debt reserve the right to require that any TreasuryDirect ® transaction be conducted in paper form? We reserve the right to require any...

Environmental assessment of the brine pipeline replacement for the Strategic Petroleum Reserve Bryan Mound Facility in Brazoria County, Texas

Energy Technology Data Exchange (ETDEWEB)

1993-09-01

The Department of Energy (DOE) has prepared an environmental assessment (EA), DOE/EA-0804, for the proposed replacement of a deteriorated brine disposal pipeline from the Strategic Petroleum Reserve (SPR) Bryan Mound storage facility in Brazoria County, Texas, into the Gulf of Mexico. In addition, the ocean discharge outfall would be moved shoreward by locating the brine diffuser at the end of the pipeline 3.5 miles offshore at a minimum depth of 30 feet. The action would occur in a floodplain and wetlands; therefore, a floodplain/wetlands assessment has been prepared in conjunction with this EA. Based on the analyses in the EA, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) of 1969 (42 USC. 4321, et seg.). Therefore, the preparation of an Environmental Impact Statement (EIS) is not required, and the Department is issuing this Finding of No Significant Impact (FONSI). This FONSI also includes a Floodplain Statement of Findings in accordance with 10 CFR Part 1022.

Environmental assessment of the brine pipeline replacement for the Strategic Petroleum Reserve Bryan Mound Facility in Brazoria County, Texas

International Nuclear Information System (INIS)

1993-09-01

The Department of Energy (DOE) has prepared an environmental assessment (EA), DOE/EA-0804, for the proposed replacement of a deteriorated brine disposal pipeline from the Strategic Petroleum Reserve (SPR) Bryan Mound storage facility in Brazoria County, Texas, into the Gulf of Mexico. In addition, the ocean discharge outfall would be moved shoreward by locating the brine diffuser at the end of the pipeline 3.5 miles offshore at a minimum depth of 30 feet. The action would occur in a floodplain and wetlands; therefore, a floodplain/wetlands assessment has been prepared in conjunction with this EA. Based on the analyses in the EA, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) of 1969 (42 USC. 4321, et seg.). Therefore, the preparation of an Environmental Impact Statement (EIS) is not required, and the Department is issuing this Finding of No Significant Impact (FONSI). This FONSI also includes a Floodplain Statement of Findings in accordance with 10 CFR Part 1022

Simultaneous Detection of Escherichia coli O157:H7, Salmonella enteritidis, and Listeria monocytogenes at a Very Low Level Using Simultaneous Enrichment Broth and Multichannel SPR Biosensor.

Science.gov (United States)

Zhang, Xiaoguang; Tsuji, Sachiko; Kitaoka, Hayato; Kobayashi, Hiroshi; Tamai, Mitsuru; Honjoh, Ken-Ichi; Miyamoto, Takahisa

2017-10-01

Detection of foodborne pathogens at very low levels is still a challenge. A custom-built multichannel surface plasmon resonance (SPR) biosensor and simultaneous enrichment broth (SEB) were used to develop a simultaneous detection method for 3 important foodborne pathogens, Escherichia coli O157:H7 (O157:H7), Salmonella enteritidis, and Listeria monocytogenes, at a very low level. These 3 foodborne pathogens at a very low level (14, 6, and 28 CFU/25 g (mL) for O157:H7, S. enteritidis, and L. monocytogenes, respectively) were inoculated in SEB and incubated at 37 ˚C for 24 h. Sample prepared from the simultaneous enrichment culture was analyzed using the multichannel SPR biosensor and sensor chip immobilized with polyclonal antibodies specific to each of the target pathogens. O157:H7, S. enteritidis, and L. monocytogenes in chicken were detected simultaneously at an inoculum dose of 14, 6, and 28 CFU/25 g, respectively. Our method using a custom-built multichannel SPR biosensor and enrichment in SEB is expected as a rapid and simultaneous detection method for low levels of O157:H7, S. enteritidis, and L. monocytogenes in food. Our method is expected as a rapid and simultaneous detection method for pathogens at very low levels. It has great potential for safety control of food and microbiological detection applications. © 2017 Institute of Food Technologists®.

Investigation of SnSPR1, a novel and abundant surface protein of Sarcocystis neurona merozoites.

Science.gov (United States)

Zhang, Deqing; Howe, Daniel K

2008-04-15

An expressed sequence tag (EST) sequencing project has produced over 15,000 partial cDNA sequences from the equine pathogen Sarcocystis neurona. While many of the sequences are clear homologues of previously characterized genes, a significant number of the S. neurona ESTs do not exhibit similarity to anything in the extensive sequence databases that have been generated. In an effort to characterize parasite proteins that are novel to S. neurona, a seemingly unique gene was selected for further investigation based on its abundant representation in the collection of ESTs and the predicted presence of a signal peptide and glycolipid anchor addition on the encoded protein. The gene was expressed in E. coli, and monospecific polyclonal antiserum against the recombinant protein was produced by immunization of a rabbit. Characterization of the native protein in S. neurona merozoites and schizonts revealed that it is a low molecular weight surface protein that is expressed throughout intracellular development of the parasite. The protein was designated Surface Protein 1 (SPR1) to reflect its display on the outer surface of merozoites and to distinguish it from the ubiquitous SAG/SRS surface antigens of the heteroxenous Coccidia. Interestingly, infection assays in the presence of the polyclonal antiserum suggested that SnSPR1 plays some role in attachment and/or invasion of host cells by S. neurona merozoites. The work described herein represents a general template for selecting and characterizing the various unidentified gene sequences that are plentiful in the EST databases for S. neurona and other apicomplexans. Furthermore, this study illustrates the value of investigating these novel sequences since it can offer new candidates for diagnostic or vaccine development while also providing greater insight into the biology of these parasites.

Implementation of a SPR immunosensor for the simultaneous detection of the 22K and 20K hGH isoforms in human serum samples.

Science.gov (United States)

de Juan-Franco, Elena; Rodríguez-Frade, J M; Mellado, M; Lechuga, Laura M

2013-09-30

We have implemented a Surface Plasmon Resonance (SPR) immunosensor based on a sandwich assay for the simultaneous detection of the two main hGH isoforms, of 22 kDa (22K) and 20 kDa (20K). An oriented-antibody sensor surface specific for both hormone isoforms was assembled by using the biotin-streptavidin system. The immunosensor functionality was checked for the direct detection of the 22K hGH isoform in buffer, which gave high specificity and reproducibility (intra and inter-assay mean coefficients of variation of 8.23% and 9% respectively). The selective determination of the 22K and 20K hGH isoforms in human serum samples in a single assay was possible by using two specific anti-hGH monoclonal antibodies. The detection limit for both hormone isoforms was 0.9 ng mL(-1) and the mean coefficient of variation was below 7.2%. The excellent reproducibility and sensitivity obtained indicate the high performance of this immunosensor for implementing an anti-doping test. Copyright © 2013 Elsevier B.V. All rights reserved.

Protein-Flavonoid Interaction Studies by a Taylor Dispersion Surface Plasmon Resonance (SPR Technique: A Novel Method to Assess Biomolecular Interactions

Directory of Open Access Journals (Sweden)

Preejith P. Vachali

2016-02-01

Full Text Available Flavonoids are common polyphenolic compounds widely distributed in fruits and vegetables. These pigments have important pharmacological relevance because emerging research suggests possible anti-cancer and anti-inflammatory properties as well other beneficial health effects. These compounds are relatively hydrophobic molecules, suggesting the role of blood transport proteins in their delivery to tissues. In this study, we assess the binding interactions of four flavonoids (kaempferol, luteolin, quercetin, and resveratrol with human serum albumin (HSA, the most abundant protein in the blood, and with glutathione S-transferase pi isoform-1 (GSTP1, an enzyme with well-characterized hydrophobic binding sites that plays an important role in detoxification of xenobiotics with reduced glutathione, using a novel Taylor dispersion surface plasmon resonance (SPR technique. For the first time, HSA sites revealed a high-affinity binding site for flavonoid interactions. Out of the four flavonoids that we examined, quercetin and kaempferol showed the strongest equilibrium binding affinities (KD of 63 ± 0.03 nM and 37 ± 0.07 nM, respectively. GSTP1 displayed lower affinities in the micromolar range towards all of the flavonoids tested. The interactions of flavonoids with HSA and GSTP1 were studied successfully using this novel SPR assay method. The new method is compatible with both kinetic and equilibrium analyses.

Facility management - efektivní správa stavebních objektů

OpenAIRE

Helekalová, Denisa

2013-01-01

Diplomová práce „ Facility management – efektivní správa stavebních objektů“ je zaměřena na stavební objekty a přínos pro ně při využívání služeb facility managementu. Práce se snaží přiblížit, co je facility management kdo ho poskytuje v České republice a jak přispívá k úsporám. Zmíněny jsou také informační technologie využívané ve facility managementu, protože bez těch se v dnešní době téměř žádný obor neobejde. První část je též zaměřena na stavbu, její životní cyklus a náklady s ním spoje...

Production of a broad specificity antibody for the development and validation of an optical SPR screening method for free and intracellular microcystins and nodularin in cyanobacteria cultures.

Science.gov (United States)

Devlin, Shauna; Meneely, Julie P; Greer, Brett; Campbell, Katrina; Vasconcelos, Vitor; Elliott, Christopher T

2014-05-01

A highly sensitive broad specificity monoclonal antibody was produced and characterised for microcystin detection through the development of a rapid surface plasmon resonance (SPR) optical biosensor based immunoassay. The antibody displayed the following cross-reactivity: MC-LR 100%; MC-RR 108%; MC-YR 68%; MC-LA 69%; MC-LW 71%; MC-LF 68%; and Nodularin 94%. Microcystin-LR was covalently attached to a CM5 chip and with the monoclonal antibody was employed in a competitive 4 min injection assay to detect total microcystins in water samples below the WHO recommended limit (1 µg/L). A 'total microcystin' level was determined by measuring free and intracellular concentrations in cyanobacterial culture samples as this toxin is an endotoxin. Glass bead beating was used to lyse the cells as a rapid extraction procedure. This method was validated according to European Commission Decision 96/23/EC criteria. The method was proven to measure intracellular microcystin levels, the main source of the toxin, which often goes undetected by other analytical procedures and is advantageous in that it can be used for the monitoring of blooms to provide an early warning of toxicity. It was shown to be repeatable and reproducible, with recoveries from spiked samples ranging from 74 to 123%, and had % CVs below 10% for intra-assay analysis and 15% for inter-assay analysis. The detection capability of the assay was calculated as 0.5 ng/mL for extracellular toxins and 0.05 ng/mL for intracellular microcystins. A comparison of the SPR method with LC-MS/MS was achieved by testing six Microcystis aeruginosa cultures and this study yielded a correlation R(2) value of 0.9989. Copyright © 2014 Elsevier B.V. All rights reserved.

Required sample size for monitoring stand dynamics in strict forest reserves: a case study

Science.gov (United States)

Diego Van Den Meersschaut; Bart De Cuyper; Kris Vandekerkhove; Noel Lust

2000-01-01

Stand dynamics in European strict forest reserves are commonly monitored using inventory densities of 5 to 15 percent of the total surface. The assumption that these densities guarantee a representative image of certain parameters is critically analyzed in a case study for the parameters basal area and stem number. The required sample sizes for different accuracy and...

Use of surface plasmon resonance (SPR) to study the dissociation and polysaccharide binding of casein micelles and caseins.

Science.gov (United States)

Thompson, Abby K; Singh, Harjinder; Dalgleish, Douglas G

2010-11-24

Tests were made to determine whether surface plasmon resonance (SPR) could be used as a technique to study the dissociation properties of bovine casein micelles or of sodium caseinate and the interactions between these protein particles and different polysaccharides. Surfaces of bound micelles or caseinate were made, and the changes in refractive index of these layers were used to define changes in the structures of the chemisorbed material. The technique appears to have some potential for studying details of the dissociation of casein micelles and of the binding of different polysaccharides to caseins.

A new spinning reserve requirement forecast method for deregulated electricity markets

International Nuclear Information System (INIS)

Amjady, Nima; Keynia, Farshid

2010-01-01

Ancillary services are necessary for maintaining the security and reliability of power systems and constitute an important part of trade in competitive electricity markets. Spinning Reserve (SR) is one of the most important ancillary services for saving power system stability and integrity in response to contingencies and disturbances that continuously occur in the power systems. Hence, an accurate day-ahead forecast of SR requirement helps the Independent System Operator (ISO) to conduct a reliable and economic operation of the power system. However, SR signal has complex, non-stationary and volatile behavior along the time domain and depends greatly on system load. In this paper, a new hybrid forecast engine is proposed for SR requirement prediction. The proposed forecast engine has an iterative training mechanism composed of Levenberg-Marquadt (LM) learning algorithm and Real Coded Genetic Algorithm (RCGA), implemented on the Multi-Layer Perceptron (MLP) neural network. The proposed forecast methodology is examined by means of real data of Pennsylvania-New Jersey-Maryland (PJM) electricity market and the California ISO (CAISO) controlled grid. The obtained forecast results are presented and compared with those of the other SR forecast methods. (author)

A new spinning reserve requirement forecast method for deregulated electricity markets

Energy Technology Data Exchange (ETDEWEB)

Amjady, Nima; Keynia, Farshid [Department of Electrical Engineering, Semnan University, Semnan (Iran)

2010-06-15

Ancillary services are necessary for maintaining the security and reliability of power systems and constitute an important part of trade in competitive electricity markets. Spinning Reserve (SR) is one of the most important ancillary services for saving power system stability and integrity in response to contingencies and disturbances that continuously occur in the power systems. Hence, an accurate day-ahead forecast of SR requirement helps the Independent System Operator (ISO) to conduct a reliable and economic operation of the power system. However, SR signal has complex, non-stationary and volatile behavior along the time domain and depends greatly on system load. In this paper, a new hybrid forecast engine is proposed for SR requirement prediction. The proposed forecast engine has an iterative training mechanism composed of Levenberg-Marquadt (LM) learning algorithm and Real Coded Genetic Algorithm (RCGA), implemented on the Multi-Layer Perceptron (MLP) neural network. The proposed forecast methodology is examined by means of real data of Pennsylvania-New Jersey-Maryland (PJM) electricity market and the California ISO (CAISO) controlled grid. The obtained forecast results are presented and compared with those of the other SR forecast methods. (author)

Identification of EloR (Spr1851) as a regulator of cell elongation in Streptococcus pneumoniae.

Science.gov (United States)

Stamsås, Gro Anita; Straume, Daniel; Ruud Winther, Anja; Kjos, Morten; Frantzen, Cyril Alexander; Håvarstein, Leiv Sigve

2017-09-01

In a screen for mutations suppressing the lethal loss of PBP2b in Streptococcus pneumoniae we identified Spr1851 (named EloR), a cytoplasmic protein of unknown function whose inactivation removed the requirement for PBP2b as well as RodA. It follows from this that EloR and the two elongasome proteins must be part of the same functional network. This network also includes StkP, as this serine/threonine kinase phosphorylates EloR on threonine 89 (T89). We found that ΔeloR cells, and cells expressing the phosphoablative form of EloR (EloR T89A ), are significantly shorter than wild-type cells. Furthermore, the phosphomimetic form of EloR (EloR T89E ) is not tolerated unless the cell in addition acquires a truncated MreC or non-functional RodZ protein. By itself, truncation of MreC as well as inactivation of RodZ gives rise to less elongated cells, demonstrating that the stress exerted by the phosphomimetic form of EloR is relieved by suppressor mutations that reduce or abolish the activity of the elongasome. Of note, it was also found that loss of elongasome activity caused by truncation of MreC elicits increased StkP-mediated phosphorylation of EloR. Together, the results support a model in which phosphorylation of EloR stimulates cell elongation, while dephosphorylation has an inhibitory effect. © 2017 John Wiley & Sons Ltd.

The Strategic Petroleum Reserve: History, Perspectives, and Issues

Science.gov (United States)

2009-12-28

Germany , Greece, Hungary, Ireland, Italy, Japan, Republic of Korea, Luxembourg, the Netherlands, New Zealand, Norway, Portugal, Spain, Sweden...Iran. Firms providing, or insuring tankers carrying, refined product to Iran would also be included in the prohibition. The Drawdown Authorities The...taking place in the operation of oil markets after the experiences of the 1970s, and deregulation of oil price and supply. Sales of SPR oil authorized

Design and analysis of surface plasmon resonance (SPR) sensor to check the quality of food from adulteration

Science.gov (United States)

Kumar, Manish; Raghuwanshi, Sanjeev Kumar

2018-02-01

In recent years, food safety issues caused by contamination of chemical substances or microbial species have raised a major area of concern to mankind. The conventional chromatography-based methods for detection of chemical are based on human-observation and slow for real-time monitoring. The surface plasmon resonance (SPR) sensors offers the capability of detection of very low concentrations of adulterated chemical and biological agents for real-time by monitoring. Thus, adulterant agent in food gives change in refractive index of pure food result in corresponding phase change. These changes can be detected at the output and can be related to the concentration of the chemical species present at the point.

76 FR 64250 - Reserve Requirements of Depository Institutions: Reserves Simplification and Private Sector...

Science.gov (United States)

2011-10-18

... Simplification and Private Sector Adjustment Factor AGENCY: Board of Governors of the Federal Reserve System... comment on several issues related to the methodology used for the Private Sector Adjustment Factor that is... Analyst (202) 452- 3674, Division of Monetary Affairs, or, for questions regarding the Private Sector...

China's optimal stockpiling policies in the context of new oil price trend

International Nuclear Information System (INIS)

Xie, Nan; Yan, Zhijun; Zhou, Yi; Huang, Wenjun

2017-01-01

Optimizing the size of oil stockpiling plays a fundamental role in the process of making national strategic petroleum reserve (SPR) policies. There have been extensive studies on the operating strategies of SPR. However, previous literatures have paid more attention to a booming or stable international oil market, while few studies analyzed the impact of a long-term low oil price on SPR policy. As a supplement, this paper extends a static model to study China's optimal stockpiling policy under different oil price trends, and in response to different current oil prices. A new variable “FC”, which demonstrates the appreciation and depreciation of the reserved oil economic value, has been taken into account to assess the optimal size of SPR. In this paper, a more multi-perspective of view is provided to consider the policies of China's SPR, especially under the different trend of international oil price fluctuations. - Highlights: • We extended a static model to study optimal stockpiling size of China's SPR. • A new variable “FC” was applied to illustrate the shifting financial value of SPR. • We analyzed how current oil price and varied prediction influence optimal size. • Operational measures could be adjusted at the end of each decision-making period. • A more multifaceted of view might be provided for China's SPR policy-making.

Analysis of Multi-Arm Caliper Data for the U.S. Strategic Petroleum Reserve

Energy Technology Data Exchange (ETDEWEB)

Roberts, Barry L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2015-03-01

The U.S. Strategic Petroleum Reserve (SPR) has an increasing reliance on mul t i - arm caliper surveys to assess the integrity of casing for cavern access wells and to determine priorities for casing remediation. Multi - arm caliper (MAC) surveys provide a view of well casing deformation by reporting radial measurements of the inner cas ing wall as the tool is drawn through the casing. Over the last several years the SPR has collected a large number of modern MAC surveys. In total, these surveys account for over 100 million individual measurements. The surveys were collected using diff ering survey vendors and survey hardware. This has resulted in a collection of disparate data sets which confound attempts to make well - to - well or time - dependent evaluations. In addition, the vendor supplied MAC interpretations often involve variables wh ich are not well defined or which may not be applicable to casings for cavern access wells. These factors reduce the usability of these detailed data sets. In order to address this issue and provide an independent analysis of multi - arm caliper survey data, Sandia National Labs has developed processing techniques and analysis variables which allow for the comparison of MAC survey data regardless of the source of the survey data. These techniques use the raw radial arm information and newly developed analysis variables to assess the casing status and provide a means for well - to - well and time - dependent analyses. Well - to - well and t ime - dependent investigation of the MAC survey data provide s information to prioritize well remediation activities and identify wells with integrity issues. This paper presents the challenges in using disparate MAC survey data, techniques developed to address these challenges and some o f the insights gained from these new techniques.

Kinetic analysis of inhibition of glucoamylase and active site mutants via chemoselective oxime immobilization of acarbose on SPR chip surfaces

DEFF Research Database (Denmark)

Sauer, Jørgen; Abou Hachem, Maher; Svensson, Birte

2013-01-01

shown that at pH 7.0 the association and dissociation rate constants for the acarbose-glucoamylase interaction are 104M−1s−1 and 103s−1, respectively, and that the conformational change to a tight enzyme–inhibitor complex affects the dissociation rate constant by a factor of 102s−1. Additionally......, the acarbose-presenting SPR surfaces could be used as a glucoamylase sensor that allowed rapid, label-free affinity screening of small carbohydrate-based inhibitors in solution, which is otherwise difficult with immobilized enzymes or other proteins....

26 CFR 1.801-5 - Total reserves.

Science.gov (United States)

2010-04-01

... TAXES Life Insurance Companies § 1.801-5 Total reserves. (a) Total reserves defined. For purposes of... its highest aggregate reserve by taking State A's requirement of 10 against its life insurance business and adding it to State B's requirement of 7 against its annuity business. (b) Reserves required by...

HAHA--nothing to laugh about. Measuring the immunogenicity (human anti-human antibody response) induced by humanized monoclonal antibodies applying ELISA and SPR technology.

Science.gov (United States)

Nechansky, Andreas

2010-01-05

Immunogenicity induced by passively applied proteins is a serious issue because it is directly related to the patient's safety. The out-come of an immune reaction to a therapeutic protein can range from transient appearance of antibodies without any clinical significance to severe life threatening conditions. Within this article, enzyme-linked immunosorbent assay (ELISA) and surface plasmon resonance (SPR) methodology to measure immunogenicity are compared and the pros and cons are discussed.

The Impact of the Required Reserve on the Monetary Multiplication in the Republic of Macedonias

Directory of Open Access Journals (Sweden)

Aleksandar Dejanovski

2014-11-01

Full Text Available One of the primary and most important tasks of any central bank is conducting monetary policy in the state. In Macedonia the only central and issuing bank is the National Bank of Macedonia, which is responsible for the monetary and financial stability in the country, while performing important functions, without which the overall economic and financial system could not exist. In exercising its functions, the National Bank of Macedonia uses a set of economic instruments and policies, from which in RM the most efective is the required resserve. This monetary tool is showing the best results in developing countries where the financial markets are not developed and where there is a high concentration of the banking sector (in RM banks occupy a good 98% of total financial institutions. The role of the reserve will be analyzed through the prism of its effects on the process of multiplication the money supply in the country and its contribution to generating or withdrawal of money by the central bank. The main goal of the paper is to research the required reserve, as a monetary instrument, and to qualify its impact on the monetary creation in the Republic of Macedonia. The basic methods, used in this paper are the positive analysis, comparative analysis and deductive approach.

Introducing optional reserve ratios in Hungary

OpenAIRE

Lóránt Varga

2010-01-01

As of the reserve maintenance period commencing in November 2010, Hungarian credit institutions will be free to decide whether to apply the previously valid 2% reserve ratio, or to apply a higher mandatory reserve ratio. Credit institutions required to hold reserves may select from reserve ratios of 2, 3, 4 and 5%, and may change their decision on a semi-annual basis. In line with the international best practice, the purpose of the MNB’s reserve requirement system is to support credit institu...

12 CFR 204.5 - Maintenance of required reserves.

Science.gov (United States)

2010-01-01

... and Other Items by Federal Reserve Banks and Funds Transfers Through Fedwire” (12 CFR part 210). If a... collected funds. (d)(1) A depository institution, a U.S. branch or agency of a foreign bank, or an Edge or... institutions are Federal Home Loan Banks, the National Credit Union Administration Central Liquidity Facility...

Changes in Reserve Requirements and Brazilian Banks' Stocks

Directory of Open Access Journals (Sweden)

Bruno De Lorenzi Cancelier Mazzucco

2013-09-01

Full Text Available In this study we tested the hypothesis that part of reserve requirements’ costs is paid by banks’ stockholders, instead of only by depositors and borrowers. Through an event study of fourteen regulatory changes between 1998 and 2010, we investigated the existence of abnormal returns. The results suggest that stockholders share the costs.

Development of an SPR imaging biosensor for determination of cathepsin G in saliva and white blood cells

International Nuclear Information System (INIS)

Gorodkiewicz, E.; Wojtulewski, K.; Regulska, E.

2011-01-01

Cathepsin G (CatG) is an endopeptidase that is associated with the early immune response. The synthetic compound cathepsin G inhibitor I (CGI-I) was tested for its ability to inhibit the activity of CatG via a new surface plasmon resonance imaging assay. CGI-I was immobilized on the gold surface of an SPR sensor that was first modified with 1-octadecanethiol. A concentration of CGI-I equal to 4.0 μg.mL -1 and a pH of 8.0 were found to give the best results. The dynamic response of the sensor ranges from 0. 25 to 1. 5 ng.mL -1 , and the detection limit is 0. 12 ng.mL -1 . The sensor was applied to detect CatG in human saliva and white blood cells. (author)

24 CFR 904.111 - Nonroutine Maintenance Reserve (NRMR).

Science.gov (United States)

2010-04-01

... the annual reserve requirement, and (3) show the total reserve requirements for all the listed items... reserve requirements for 90 days the LHA shall invest the excess in federally insured savings accounts... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Nonroutine Maintenance Reserve...

Mentha spicata L. infusions as sources of antioxidant phenolic compounds: emerging reserve lots with special harvest requirements.

Science.gov (United States)

Rita, Ingride; Pereira, Carla; Barros, Lillian; Santos-Buelga, Celestino; Ferreira, Isabel C F R

2016-10-12

Mentha spicata L., commonly known as spearmint, is widely used in both fresh and dry forms, for infusion preparation or in European and Indian cuisines. Recently, with the evolution of the tea market, several novel products with added value are emerging, and the standard lots have evolved to reserve lots, with special harvest requirements that confer them with enhanced organoleptic and sensorial characteristics. The apical leaves of these batches are collected in specific conditions having, then, a different chemical profile. In the present study, standard and reserve lots of M. spicata were assessed in terms of the antioxidants present in infusions prepared from the different lots. The reserve lots presented the highest concentration in all the compounds identified in relation to the standard lots, with 326 and 188 μg mL -1 of total phenolic compounds, respectively. Both types of samples presented rosmarinic acid as the most abundant phenolic compound, at concentrations of 169 and 101 μg mL -1 for reserve and standard lots, respectively. The antioxidant activity was higher in the reserve lots which had the highest total phenolic compounds content, with EC 50 values ranging from 152 to 336 μg mL -1 . The obtained results provide scientific information that may allow the consumer to make a conscientious choice.

THE IMPLEMENTATION OF EFFICIENT TRADE MATRIX AND GOLD RESERVE REQUIREMENT FOR COMMODITY TRADE AMONG ASEAN COUNTRIES

OpenAIRE

nurul anisak

2017-01-01

Objective - This study attempts to implement the efficient trade matrix among five selected ASEAN countries and its settlement by the gold reserve requirements through Multi-Bilateral Payments Arrangement (MBPA).Methods – The study is a qualitative research with analytic description. The purpose of this qualitative-descriptive study is to simulate the implementation of gold in the Multi-Bilateral Payment Arrangement among ASEAN countries using the current trade data.Results – This paper argue...

Quantitative monitoring of two simultaneously binding species using Label-Enhanced surface plasmon resonance.

Science.gov (United States)

Eng, Lars; Garcia, Brandon L; Geisbrecht, Brian V; Hanning, Anders

2018-02-26

Surface plasmon resonance (SPR) is a well-established method for biomolecular interaction studies. SPR monitors the binding of molecules to a solid surface, embodied as refractive index changes close to the surface. One limitation of conventional SPR is the universal nature of the detection that results in an inability to qualitatively discriminate between different binding species. Furthermore, it is impossible to directly discriminate two species simultaneously binding to different sites on a protein, which limits the utility of SPR, for example, in the study of allosteric binders or bi-specific molecules. It is also impossible in principle to discriminate protein conformation changes from actual binding events. Here we demonstrate how Label-Enhanced SPR can be utilized to discriminate and quantitatively monitor the simultaneous binding of two different species - one dye-labeled and one unlabeled - on a standard, single-wavelength SPR instrument. This new technique increases the versatility of SPR technology by opening up application areas where the usefulness of the approach has previously been limited. Copyright © 2018 Elsevier Inc. All rights reserved.

Site-directed antibody immobilization using a protein A-gold binding domain fusion protein for enhanced SPR immunosensing.

Science.gov (United States)

de Juan-Franco, Elena; Caruz, Antonio; Pedrajas, J R; Lechuga, Laura M

2013-04-07

We have implemented a novel strategy for the oriented immobilization of antibodies onto a gold surface based on the use of a fusion protein, the protein A-gold binding domain (PAG). PAG consists of a gold binding peptide (GBP) coupled to the immunoglobulin-binding domains of staphylococcal protein A. This fusion protein provides an easy and fast oriented immobilization of antibodies preserving its native structure, while leaving the antigen binding sites (Fab) freely exposed. Using this immobilization strategy, we have demonstrated the performance of the immunosensing of the human Growth Hormone by SPR. A limit of detection of 90 ng mL(-1) was obtained with an inter-chip variability lower than 7%. The comparison of this method with other strategies for the direct immobilization of antibodies over gold surfaces has showed the enhanced sensitivity provided by the PAG approach.

47 CFR 80.146 - [Reserved

Science.gov (United States)

2010-10-01

... MARITIME SERVICES Operating Requirements and Procedures Shipboard General Purpose Watches § 80.146 [Reserved] ... 47 Telecommunication 5 2010-10-01 2010-10-01 false [Reserved] 80.146 Section 80.146...

47 CFR 80.965 - Reserve power supply.

Science.gov (United States)

2010-10-01

... conditions. When meeting this 2 hour requirement, such reserve power supply must be located on the bridge... radiotelephone must be a “reserve power supply” for the purposes of paragraphs (c), (d) and (e) of this section... meeting the requirements of paragraph (a) of this section as follows: (1) When the reserve power supply...

SPR Hydrostatic Column Model Verification and Validation.

Energy Technology Data Exchange (ETDEWEB)

Bettin, Giorgia [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lord, David [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Rudeen, David Keith [Gram, Inc. Albuquerque, NM (United States)

2015-10-01

A Hydrostatic Column Model (HCM) was developed to help differentiate between normal "tight" well behavior and small-leak behavior under nitrogen for testing the pressure integrity of crude oil storage wells at the U.S. Strategic Petroleum Reserve. This effort was motivated by steady, yet distinct, pressure behavior of a series of Big Hill caverns that have been placed under nitrogen for extended period of time. This report describes the HCM model, its functional requirements, the model structure and the verification and validation process. Different modes of operation are also described, which illustrate how the software can be used to model extended nitrogen monitoring and Mechanical Integrity Tests by predicting wellhead pressures along with nitrogen interface movements. Model verification has shown that the program runs correctly and it is implemented as intended. The cavern BH101 long term nitrogen test was used to validate the model which showed very good agreement with measured data. This supports the claim that the model is, in fact, capturing the relevant physical phenomena and can be used to make accurate predictions of both wellhead pressure and interface movements.

47 CFR 80.145 - [Reserved

Science.gov (United States)

2010-10-01

... MARITIME SERVICES Operating Requirements and Procedures Special Procedures-Ship Stations § 80.145 [Reserved] Shipboard General Purpose Watches ... 47 Telecommunication 5 2010-10-01 2010-10-01 false [Reserved] 80.145 Section 80.145...

Tuning the field distribution and fabrication of an Al@ZnO core-shell nanostructure for a SPR-based fiber optic phenyl hydrazine sensor.

Science.gov (United States)

Tabassum, Rana; Kaur, Parvinder; Gupta, Banshi D

2016-05-27

We report the fabrication and characterization of a surface plasmon resonance (SPR)-based fiber optic sensor that uses coatings of silver and aluminum (Al)-zinc oxide (ZnO) core-shell nanostructure (Al@ZnO) for the detection of phenyl hydrazine (Ph-Hyd). To optimize the volume fraction (f) of Al in ZnO and the thickness of the core-shell nanostructure layer (d), the electric field intensity along the normal to the multilayer system is simulated using the two-dimensional multilayer matrix method. The Al@ZnO core-shell nanostructure is prepared using the laser ablation technique. Various probes are fabricated with different values of f and an optimized thickness of core-shell nanostructure for the characterization of the Ph-Hyd sensor. The performance of the Ph-Hyd sensor is evaluated in terms of sensitivity. It is found that the Ag/Al@ZnO nanostructure core-shell-coated SPR probe with f = 0.25 and d = 0.040 μm possesses the maximum sensitivity towards Ph-Hyd. These results are in agreement with the simulated ones obtained using electric field intensity. In addition, the performance of the proposed probe is compared with that of probes coated with (i) Al@ZnO nanocomposite, (ii) Al nanoparticles and (iii) ZnO nanoparticles. It is found that the probe coated with an Al@ZnO core-shell nanostructure shows the largest resonance wavelength shift. The detailed mechanism of the sensing (involving chemical reactions) is presented. The sensor also manifests optimum performance at pH 7.

Professionalizing the Estonian Reserve Component

National Research Council Canada - National Science Library

Everett, William

1998-01-01

.... In particular, citizen-soldier reserves can allow nations that do not face immediate external threats, such as Estonia, to meet their security requirements for less money than required by standing forces...

A Mathematical Model and Programme Support for Determination of the Values of the Marginal Reserve Requirement as Instrument of Monetary Policy

Directory of Open Access Journals (Sweden)

Kristina Šorić

2007-09-01

Full Text Available This paper studies the problem of interdependence between central bank and commercial bank goals. The basic central bank task is to achieve and to maintain price stability. Croatian external debt has been increasing for years and so the activities of the Croatian National Bank are designed to correct this situation. In order to stop the further increase of the external debt, the Croatian National Bank uses several monetary policy instruments, among which is the marginal reserve requirement. On the other hand, the goal of commercial banks is to maximise profits. Banks take loans from abroad at a lower interest rate and invest this money in Croatia at a higher interest rate, thus fulfilling their goal. In order to obtain the desired effects of the marginal reserve requirement, its optimal percentage value should be determined. This problem is modelled as a bi-level mixed 0-1 programming problem. The objective of the leader (Croatian National Bank is to minimize the increase in household loans by setting different percentages of the reserve requirements for loans extended to households and for those granted to enterprises. The objective of the followers (banks is to maximize profits. In order to solve this NP-hard problem a heuristic is proposed. In order to verify the model, the paper ends with simulations and the presentation of computational results.

Requirement for Naval Reserve Component Units Not Assigned to Support Regional Contingencies

National Research Council Canada - National Science Library

Gimble, Thomas

1996-01-01

Our primary objective was to determine whether a valid need exists for Naval Reserve units and non-unit Reserve personnel who are not assigned to meet the needs of anticipated regional contingencies...

An Aptamer Bio-barCode (ABC) assay using SPR, RNase H, and probes with RNA and gold-nanorods for anti-cancer drug screening.

Science.gov (United States)

Loo, Jacky Fong-Chuen; Yang, Chengbin; Tsang, Hing Lun; Lau, Pui Man; Yong, Ken-Tye; Ho, Ho Pui; Kong, Siu Kai

2017-10-07

With modifications to an ultra-sensitive bio-barcode (BBC) assay, we have developed a next generation aptamer-based bio-barcode (ABC) assay to detect cytochrome-c (Cyto-c), a cell death marker released from cancer cells, for anti-cancer drug screening. An aptamer is a short single-stranded DNA selected from a synthetic DNA library that is capable of binding to its target with high affinity and specificity based on its unique DNA sequence and 3D structure after folding. Similar to the BBC assay, Cyto-c is captured by a micro-magnetic particle (MMP) coated with capturing antibodies (Ab) and an aptamer specifically against Cyto-c to form sandwich structures ([MMP-Ab]-[Cyto-c]-[Aptamer]). After washing and melting, our aptamers, acting as a DNA bio-barcode, are released from the sandwiches and hybridized with the probes specially designed for RNase H for surface plasmon resonance (SPR) sensing. In an aptamer-probe duplex, RNase H digests the RNA in the probe and releases the intact aptamer for another round of hybridization and digestion. With signal enhancement effects from gold-nanorods (Au-NRs) on probes for SPR sensing, the detection limit was found to be 1 nM for the aptamer and 80 pM for Cyto-c. Without the time-consuming DNA amplification steps by PCR, the detection process of this new ABC assay can be completed within three hours. As a proof-of-concept, phenylarsine oxide was found to be a potent agent to kill liver cancer cells with multi-drug resistance at the nano-molar level. This approach thus provides a fast, sensitive and robust tool for anti-cancer drug screening.

THE IMPLEMENTATION OF EFFICIENT TRADE MATRIX AND GOLD RESERVE REQUIREMENT FOR COMMODITY TRADE AMONG ASEAN COUNTRIES

Directory of Open Access Journals (Sweden)

nurul anisak

2017-06-01

Full Text Available Objective - This study attempts to implement the efficient trade matrix among five selected ASEAN countries and its settlement by the gold reserve requirements through Multi-Bilateral Payments Arrangement (MBPA.Methods – The study is a qualitative research with analytic description. The purpose of this qualitative-descriptive study is to simulate the implementation of gold in the Multi-Bilateral Payment Arrangement among ASEAN countries using the current trade data.Results – This paper argues that the Southeast Asian countries can solve the problem through their internal coordination, particularly in terms of trade. One of the efforts is to reduce even eliminate the market risk by using the efficient payment arrangement.Conclusions – The study implied that the quantity amount of gold required to settle the trade balance will be reduced from the early gross payment. However, the ASEAN countries need to strengthen the cooperation among them through maximizing the trade relationship.

24 CFR 572.125 - Replacement reserves.

Science.gov (United States)

2010-04-01

...) Homeownership Program Requirements-Implementation Grants § 572.125 Replacement reserves. (a) Purpose. A single replacement reserve may be established for the homeownership program only if HUD determines it is necessary to... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Replacement reserves. 572.125...

Arabidopsis plastidial folylpolyglutamate synthetase is required for seed reserve accumulation and seedling establishment in darkness.

Directory of Open Access Journals (Sweden)

Hongyan Meng

Full Text Available Interactions among metabolic pathways are important in plant biology. At present, not much is known about how folate metabolism affects other metabolic pathways in plants. Here we report a T-DNA insertion mutant (atdfb-3 of the plastidial folylpolyglutamate synthetase gene (AtDFB was defective in seed reserves and skotomorphogenesis. Lower carbon (C and higher nitrogen (N content in the mutant seeds than that of the wild type were indicative of an altered C and N partitioning capacity. Higher levels of organic acids and sugars were detected in the mutant seeds compared with the wild type. Further analysis revealed that atdfb-3 seeds contained less total amino acids and individual Asn and Glu as well as NO3-. These results indicate significant changes in seed storage in the mutant. Defects in hypocotyl elongation were observed in atdfb-3 in darkness under sufficient NO3- conditions, and further enhanced under NO3- limited conditions. The strong expression of AtDFB in cotyledons and hypocotyl during early developmental stage was consistent with the mutant sensitivity to limited NO3- during a narrow developmental window. Exogenous 5-formyl-tetrahydrofolate completely restored the hypocotyl length in atdfb-3 seedlings with NO3- as the sole N source. Further study demonstrated that folate profiling and N metabolism were perturbed in atdfb-3 etiolated seedlings. The activity of enzymes involved in N reduction and assimilation was altered in atdfb-3. Taken together, these results indicate that AtDFB is required for seed reserves, hypocotyl elongation and N metabolism in darkness, providing novel insights into potential associations of folate metabolism with seed reserve accumulation, N metabolism and hypocotyl development in Arabidopsis.

Effect of laser energy on the SPR and size of silver nanoparticles synthesized by pulsed laser ablation in distilled water

Science.gov (United States)

Baruah, Prahlad K.; Sharma, Ashwini K.; Khare, Alika

2018-04-01

The effect of incident laser energy on the surface plasmon resonance (SPR) and size of silver nanoparticles synthesized via pulsed laser ablation of silver immersed in distilled water is reported in this paper. The broadening in the plasmonic bandwidth of the synthesized nanoparticles with the increase in the laser energy incident onto the silver target indicates the reduction in size of the nanoparticles. This is confirmed by the transmission electron microscope (TEM) images which show a decrease in the average particle size of the nanoparticles from approximately 15 to 10 nm with the increase in incident laser energy from 30 to 70 mJ, respectively. The structural features as revealed by the selected area electron diffraction and ultra-high resolution TEM studies confirmed the formation of both silver as well as silver oxide nanoparticles.

MIPs are ancestral ligands for the sex peptide receptor.

Science.gov (United States)

Kim, Young-Joon; Bartalska, Katarina; Audsley, Neil; Yamanaka, Naoki; Yapici, Nilay; Lee, Ju-Youn; Kim, Yong-Chul; Markovic, Milica; Isaac, Elwyn; Tanaka, Yoshiaki; Dickson, Barry J

2010-04-06

Upon mating, females of many animal species undergo dramatic changes in their behavior. In Drosophila melanogaster, postmating behaviors are triggered by sex peptide (SP), which is produced in the male seminal fluid and transferred to female during copulation. SP modulates female behaviors via sex peptide receptor (SPR) located in a small subset of internal sensory neurons that innervate the female uterus and project to the CNS. Although required for postmating responses only in these female sensory neurons, SPR is expressed broadly in the CNS of both sexes. Moreover, SPR is also encoded in the genomes of insects that lack obvious SP orthologs. These observations suggest that SPR may have additional ligands and functions. Here, we identify myoinhibitory peptides (MIPs) as a second family of SPR ligands that is conserved across a wide range of invertebrate species. MIPs are potent agonists for Drosophila, Aedes, and Aplysia SPRs in vitro, yet are unable to trigger postmating responses in vivo. In contrast to SP, MIPs are not produced in male reproductive organs, and are not required for postmating behaviors in Drosophila females. We conclude that MIPs are evolutionarily conserved ligands for SPR, which are likely to mediate functions other than the regulation of female reproductive behaviors.

24 CFR 891.745 - Replacement reserve.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Replacement reserve. 891.745... and Individuals-Section 162 Assistance § 891.745 Replacement reserve. The general requirements for the replacement reserve are provided in § 891.605. For projects funded under §§ 891.655 through 891.790, the...

Calculation program development for spinning reserve

International Nuclear Information System (INIS)

1979-01-01

This study is about optimal holding of spinning reserve and optimal operation for it. It deals with the purpose and contents of the study, introduction of the spinning reserve electricity, speciality of the spinning reserve power, the result of calculation, analysis for limited method of optimum load, calculation of requirement for spinning reserve, analysis on measurement of system stability with summary, purpose of the analysis, cause of impact of the accident, basics on measurement of spinning reserve and conclusion. It has the reference on explanation for design of spinning reserve power program and using and trend about spinning reserve power in Korea.

78 FR 50038 - National Estuarine Research Reserve System

Science.gov (United States)

2013-08-16

....33(c), the revised plan meets the reserve's requirements for compliance. The Wells Reserve Management... Reserve System AGENCY: Estuarine Reserves Division, Office of Ocean and Coastal Resource Management.... ACTION: Notice of Public Comment Period for the Wells, Maine National Estuarine Research Reserve...

12 CFR 204.6 - Charges for reserve deficiencies.

Science.gov (United States)

2010-01-01

... negligence or conduct that is inconsistent with the principles and purposes of reserve requirements... individual case and the depository institution's reserve maintenance record. For example, a waiver may be... deficiency. (c) In individual cases, where a Federal supervisory authority waives a liquidity requirement, or...

Biologia floral e visitantes de Gaylussacia brasiliensis (Spr. Meissner (Ericaceae - uma espécie com anteras poricidas polinizada por beija-flores Floral biology and visitors of Gaylussacia brasiliensis (Spr. Meissner (Ericaceae - a poricidal anther species pollinated by hummingbirds

Directory of Open Access Journals (Sweden)

Francielle Paulina de Araújo

2011-06-01

Full Text Available A biologia floral de Gaylussacia brasiliensis (Spr. Meissner (Ericaceae foi estudada na borda de uma mata de galeria na reserva ecológica do Clube de Caça e Pesca Itororó de Uberlândia, Minas Gerais. G. brasiliensis é um arbusto que pode alcançar de 0,3 a 3,0 m de altura e ocorre de forma isolada ou agregada. Apresenta floração contínua e possui inflorescências racemosas, axilares com flores pendentes. As flores são hermafroditas, vermelhas, de corola urceolada, apresentam antese diurna e ausência odor. O néctar apresentou volume de cerca de 3,0 μL e concentração de açúcares por volta de 13%. G. brasiliensis é autocompatível, não apresenta autopolinização espontânea e nem apomixia. Os polinizadores foram os beijaflores: Chlorostlibon lucidus (Shaw, Amazilia fimbirata (Gmelin, Hylocharis chrysura (Shaw (Throchilinae e Phaethornis pretrei (Lesson & DeLattre (Phaethornithinae. G. brasiliensis apresenta anteras poricidas com poros amplos e os beija-flores, quando adejam com o bico inserido nas flores em busca de néctar, fornecem a vibração necessária para a liberação dos grãos de pólen. Apesar de apresentar volume e concentração de açúcar no néctar relativamente pequenos, os agrupamentos de indivíduos com muitas flores parecem atrair beija-flores com comportamento territorial.The floral biology of Gaylussacia brasiliensis (Spr. Meissner (Ericaceae was studied on swampy edges of a gallery forest in Uberlandia, Minas Gerais. Gaylussacia brasiliensis is a shrub 0.3 to 3.0 m tall that occurs isolated or aggregated and has continuous flowering. The axillary racemose inflorescences produce four to dozens of pendulous flowers. The flowers are hermaphroditic, red, urceolate, odorless and have diurnal anthesis. Concentration of sugars in nectar was c. 13% and volume c. 3.0 μL. G. brasiliensis is a self-compatible, non apomictic species, which does not present spontaneous self-pollination. The pollinators of G

A hybrid approach to predict the relationship between tablet tensile strength and compaction pressure using analytical powder compression.

Science.gov (United States)

Persson, Ann-Sofie; Alderborn, Göran

2018-04-01

The objective was to present a hybrid approach to predict the strength-pressure relationship (SPR) of tablets using common compression parameters and a single measurement of tablet tensile strength. Experimental SPR were derived for six pharmaceutical powders with brittle and ductile properties and compared to predicted SPR based on a three-stage approach. The prediction was based on the Kawakita b -1 parameter and the in-die Heckel yield stress, an estimate of maximal tensile strength, and a parameter proportionality factor α. Three values of α were used to investigate the influence of the parameter on the SPR. The experimental SPR could satisfactorily be described by the three stage model, however for sodium bicarbonate the tensile strength plateau could not be observed experimentally. The shape of the predicted SPR was to a minor extent influenced by the Kawakita b -1 but the width of the linear region was highly influenced by α. An increased α increased the width of the linear region and thus also the maximal predicted tablet tensile strength. Furthermore, the correspondence between experimental and predicted SPR was influenced by the α value and satisfactory predictions were in general obtained for α = 4.1 indicating the predictive potential of the hybrid approach. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

7 CFR 1709.2 Policy. - [Reserved

Science.gov (United States)

2010-01-01

... 7 Agriculture 11 2010-01-01 2010-01-01 false [Reserved] 1709.2 Policy. Section 1709.2 Policy. Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE ASSISTANCE TO HIGH ENERGY COST COMMUNITIES General Requirements § 1709.2 Policy. [Reserved] ...

Environmental assessment for the Strategic Petroleum Reserve Big Hill facility storage of commercial crude oil project, Jefferson County, Texas

International Nuclear Information System (INIS)

1999-03-01

The Big Hill SPR facility located in Jefferson County, Texas has been a permitted operating crude oil storage site since 1986 with benign environmental impacts. However, Congress has not authorized crude oil purchases for the SPR since 1990, and six storage caverns at Big Hill are underutilized with 70 million barrels of available storage capacity. On February 17, 1999, the Secretary of Energy offered the 70 million barrels of available storage at Big Hill for commercial use. Interested commercial users would enter into storage contracts with DOE, and DOE would receive crude oil in lieu of dollars as rental fees. The site could potentially began to receive commercial oil in May 1999. This Environmental Assessment identified environmental changes that potentially would affect water usage, power usage, and air emissions. However, as the assessment indicates, changes would not occur to a major degree affecting the environment and no long-term short-term, cumulative or irreversible impacts have been identified

Instantaneous mechanical fastening of quasi-isotropic CFRP laminates by a self-piercing rivet

OpenAIRE

上田, 政人; 三宅, 崇太郎; 長谷川, 寛幸; 平野, 義鎭; Ueda, Masahito; Miyake, Sotaro; Hasegawa, Hiroyuki; Hirano, Yoshiyasu

2012-01-01

A modified self-piercing rivet (SPR) has been proposed to mechanically fasten CFRP laminates. The modified SPR consists of a rivet body and two flat washers. The two flat washers were used to suppress delamination in the CFRP laminates at the point of piercing. The advantages of the modified SPR for fastening CFRP laminates are instantaneous process time and low cost. Any pretreatments such as surface treatments or hole drilling are not required. In this study, the viability of the modified S...

Securities issues in reserves reporting

International Nuclear Information System (INIS)

Legg, M.B.

1997-01-01

Securities issues in oil and gas reserves reporting were discussed. Alberta requires specific information regarding important oil and gas properties, plants, facilities and installations. When preparing the reserves report, the following elements are important to consider: (1) the author of the report must be a registered professional engineer or registered professional geologist, (2) the report itself must be an engineering document, (3) the content of the report must be extensive, (4) it should be prepared in accordance with petroleum engineering and evaluation practices, and must include a summary of estimated net reserves

7 CFR 1467.9 - Wetlands Reserve Enhancement Program.

Science.gov (United States)

2010-01-01

..., restoration, and enhancement objectives through agreements with States (including a political subdivision or... project. (b) Reserved Rights Pilot. (1) The Chief shall carry out a reserved rights pilot subject to the requirements established in this part. (2) Under the reserved rights pilot, a landowner may reserve grazing...

Reserve valuation in electric power systems

Science.gov (United States)

Ruiz, Pablo Ariel

Operational reliability is provided in part by scheduling capacity in excess of the load forecast. This reserve capacity balances the uncertain power demand with the supply in real time and provides for equipment outages. Traditionally, reserve scheduling has been ensured by enforcing reserve requirements in the operations planning. An alternate approach is to employ a stochastic formulation, which allows the explicit modeling of the sources of uncertainty. This thesis compares stochastic and reserve methods and evaluates the benefits of a combined approach for the efficient management of uncertainty in the unit commitment problem. Numerical studies show that the unit commitment solutions obtained for the combined approach are robust and superior with respect to the traditional approach. These robust solutions are especially valuable in areas with a high proportion of wind power, as their built-in flexibility allows the dispatch of practically all the available wind power while minimizing the costs of operation. The scheduled reserve has an economic value since it reduces the outage costs. In several electricity markets, reserve demand functions have been implemented to take into account the value of reserve in the market clearing process. These often take the form of a step-down function at the reserve requirement level, and as such they may not appropriately represent the reserve value. The value of reserve is impacted by the reliability, dynamic and stochastic characteristics of system components, the system operation policies, and the economic aspects such as the risk preferences of the demand. In this thesis, these aspects are taken into account to approximate the reserve value and construct reserve demand functions. Illustrative examples show that the demand functions constructed have similarities with those implemented in some markets.

41 CFR 105-74.301 - [Reserved

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false [Reserved] 105-74.301 Section 105-74.301 Public Contracts and Property Management Federal Property Management Regulations System...-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Who Are...

Postextrasystolic potentiation and contractile reserve: requirements and restrictions.

Science.gov (United States)

Lust, R M; Lutherer, L O; Gardner, M E; Cooper, M W

1982-12-01

These studies were conducted to examine the basic characteristics of postextrasystolic potentiation (PESP) and the relationship of loading effects to PESP. Measurements of left ventricular (LV) and aortic pressures, the rate of pressure rise, and echocardiographically determined LV dimensions were made in anesthetized open-chest dogs. The hearts were paced, and timed extrasystoles were introduced that were followed by postextrasystoles (PES). PES's were elicited after an interval equal to either a full compensatory pause or a time when the diastolic properties of the LV could not be distinguished from control (isolength). Potentiation of contraction for the PES's introduced after an isolength pause was dependent on both the heart rate and the extrasystolic interval, whereas the PES's that occurred after a full pause showed no dependence on either of these intervals. PESP elicited during the isolength period was not dependent on either preload and afterload. It is concluded that PESP depends on the combination of heart rate and extrasystolic and postextrasystolic intervals. Further, PESP may be inaccurate in assessing contractile reserve unless the heart rate and extrasystolic interval are known and the PES is introduced after an isolength pause.

Inhibitory assay for degradation of collagen IV by cathepsin B with a surface plasmon resonance sensor.

Science.gov (United States)

Shoji, Atsushi; Suenaga, Yumiko; Hosaka, Atsushi; Ishida, Yuuki; Yanagida, Akio; Sugawara, Masao

2017-10-25

We describe a simple method for evaluating the inhibition of collagen IV degradation by cathepsin B with a surface plasmon resonance (SPR) biosensor. The change in the SPR signal decreased with an increase in the concentration of cathepsin B inhibitors. The order of the inhibitory constant (Ki) obtained by the SPR method was CA074Me≈Z-Phe-Phe-FMK < leupeptin. This order was different from that obtained by benzyloxycarbonyl-Phe-Phe-Fluoromethylketone (Z-Phe-Phe-FMK) as a peptide substrate. The comparison of Ki suggested that CA074 and Z-Phe-Phe-FMK inhibited exopeptidase activity, and leupeptin inhibited the endopeptidase activity of cathepsin B more strongly. Copyright © 2017 Elsevier B.V. All rights reserved.

7 CFR 1735.23-1735.29 - [Reserved

Science.gov (United States)

2010-01-01

... AGRICULTURE GENERAL POLICIES, TYPES OF LOANS, LOAN REQUIREMENTS-TELECOMMUNICATIONS PROGRAM Loan Purposes and Basic Policies §§ 1735.23-1735.29 [Reserved] ... 7 Agriculture 11 2010-01-01 2010-01-01 false [Reserved] 1735.23-1735.29 Section 1735.23-1735.29...

Strategic petroleum reserve caverns casing damage update 1997

Energy Technology Data Exchange (ETDEWEB)

Munson, D.E.; Molecke, M.A.; Neal, J.T. [and others

1998-01-01

Hanging casing strings are used for oil and brine transfer in the domal salt storage caverns of the Strategic Petroleum Reserve (SPR). Damage to these casings is of concern because hanging string replacement is costly and because of implications on cavern stability. Although the causes of casing damage are not always well defined, many events leading to damage are assumed to be the result of salt falls impacting the hanging strings. However, in some cases, operational aspects may be suspected. The history of damage to hanging strings is updated in this study to include the most recent events. Potential general domal and local operational and material factors that could influence the tendency for caverns to have salt falls are examined in detail. As a result of this examination, general factors, such as salt dome anomalies and crude type, and most of the operational factors, such as geometry, location and depressurizations, are not believed to be primary causes of casing damage. Further analysis is presented of the accumulation of insolubles during cavern solutioning and accumulation of salt fall material on the cavern floor. Inaccuracies in sump geometry probably make relative cavern insolubles contents uncertain. However, determination of the salt fall accumulations, which are more accurate, suggest that the caverns with the largest salt fall accumulations show the greatest number of hanging string events. There is good correlation between the accumulation rate and the number of events when the event numbers are corrected to an equivalent number for a single hanging string in a quiescent, operating cavern. The principal factor that determines the propensity for a cavern to exhibit this behavior is thought to be the effect of impurity content on the fracture behavior of salt.

12 CFR 998.3 - Reservation of authority.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Reservation of authority. 998.3 Section 998.3 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOME LOAN BANK DISCLOSURES REGISTRATION OF FEDERAL HOME LOAN BANK EQUITY SECURITIES § 998.3 Reservation of authority. The requirements of this part...

Management goals for wildlife reserves in grassveld and bushveld ...

African Journals Online (AJOL)

... and therefore require control. A means of measuring the success of management is outlined. Keywords: condition; cover; fire; game reserves; genetic diversity; goals; management; management strategy; nature reserves; range; reserves; soil; south africa; species composition; species diversity; veld; veld condition; wildlife ...

Species-specific spatial characteristics in reserve site selection

NARCIS (Netherlands)

Groeneveld, R.A.

2010-01-01

This paper addresses the problem of selecting reserve sites cost-effectively, taking into account the mobility and habitat area requirements of each species. Many reserve site selection problems are analyzed in mixed-integer linear programming (MILP) models due to the mathematical solvers available

Thermal-induced SPR tuning of Ag-ZnO nanocomposite thin film for plasmonic applications

Science.gov (United States)

Singh, S. K.; Singhal, R.

2018-05-01

The formation of silver (Ag) nanoparticles in a ZnO matrix were successfully synthesized by RF-magnetron sputtering at room temperature. As prepared Ag-ZnO nanocomposite (NCs) thin films were annealed in vacuum at three different temperatures of 300 °C, 400 °C and 500 °C, respectively. The structural modifications for as-deposited and annealed films were estimated by X-ray diffraction and TEM techniques. The crystalline behavior preferably along the c-axis of the hexagonal wurtzite structure was observed in as-deposited Ag-ZnO film and improved significantly with increasing the annealing temperature. The crystallite size of as-deposited film was measured to be 13.6 nm, and increases up to 28.5 nm at higher temperatures. The chemical composition and surface structure of the as-deposited films were estimated by X-ray photoelectron spectroscopy. The presence of Ag nanoparticles with average size of 8.2 ± 0.2 nm, was confirmed by transmission electron microscopy. The strong surface plasmon resonance (SPR) band was observed at the wavelength of ∼565 nm for as-deposited film and a remarkable red shift of ∼22 nm was recorded after the annealing treatment as confirmed by UV-visible spectroscopy. Atomic force microscopy confirmed the grain growth from 60.38 nm to 79.42 nm for as-deposited and higher temperature annealed film respectively, with no significant change in the surface roughness. Thermal induced modifications such as disordering and lattice defects in Ag-ZnO NCs thin films were carried out by Raman spectroscopy. High quality Ag-ZnO NCs thin films with minimum strain and tunable optical properties could be useful in various plasmonic applications.

[Modeling of the financial reserves required by the livestock disease compensation fund of Lower Saxony for rebates in the course of disease outbreaks incorporating spatial restriction zones].

Science.gov (United States)

Denzin, Nicolai; Gerdes, Ursula

2015-01-01

One of the tasks of the livestock disease compensation funds of the federal states in Germany is the financial compensation of livestock holders for livestock losses and costs incurred for disease control measures due to certain diseases. Usually, one half of these services are financed through financial reserves built up with the contributions paid by the owners of the respective animal species. The other half is covered by the federal state itself. But there is hardly any reference to how to calculate aforementioned financial reserves. Basically, following an approach presented recently regarding estimations concerning the compensation fund of the federal state of Saxony-Anhalt, in a stochastic modeling of the required reserves concerning the fund of Lower Saxony the anticipated costs within the spatial restriction zones allocated to outbreaks were incorporated for the first time. The overall costs (including the federal state's stakes), the share of the comnensation fund (required reserves) and the the partial costs for a total of 25 categories and subcategories and subcategories of livestock species making up the latter were estimated. It became evident that overall costs/the share of the fund were particularly determined among the diseases by foot-and-mouth disease and among the cost factors by the costs incurred for the compensation of livestock value within the areas surrounding the outbreaks in which all susceptible animals are killed (culling zone). The 80th, 90 and 95th percentile of the established probability distribution of the overall costs referred to a financial volume of about 312, 409 and 540 million euro, while the respective percentiles of the probability distribution of the required reserves of the compensation fund amounted to 175, 225 and 296 million euro.

2016 Updates to US Medical Eligibility Criteria for Contraceptive Use and Selected Practice Recommendations for Contraceptive Use: Highlights for Adolescent Patients.

Science.gov (United States)

Hoopes, Andrea J; Simmons, Katharine B; Godfrey, Emily M; Sucato, Gina S

2017-04-01

The US Medical Eligibility Criteria for Contraceptive Use (MEC) and US Selected Practice Recommendations for Contraceptive Use (SPR) provide evidence-based guidance to safely provide contraception counseling and services. Both documents were updated in 2016 and are endorsed by the North American Society for Pediatric and Adolescent Gynecology. The purpose of this mini-review is to highlight updates to the US MEC and US SPR that are most relevant to health care providers of adolescents to support dissemination and implementation of these evidence-based best practices. This document is intended to highlight these changes and to complement, not replace, the detailed practice guidance within the US MEC and US SPR. Copyright © 2017 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

Correction of resistance to penetration by pedofunctions and a reference soil water content

Directory of Open Access Journals (Sweden)

Moacir Tuzzin de Moraes

2012-12-01

Full Text Available The soil penetration resistance is an important indicator of soil compaction and is strongly influenced by soil water content. The objective of this study was to develop mathematical models to normalize soil penetration resistance (SPR, using a reference value of gravimetric soil water content (U. For this purpose, SPR was determined with an impact penetrometer, in an experiment on a Dystroferric Red Latossol (Rhodic Eutrudox, at six levels of soil compaction, induced by mechanical chiseling and additional compaction by the traffic of a harvester (four, eight, 10, and 20 passes; in addition to a control treatment under no-tillage, without chiseling or additional compaction. To broaden the range of U values, SPR was evaluated in different periods. Undisturbed soil cores were sampled to quantify the soil bulk density (BD. Pedotransfer functions were generated correlating the values of U and BD to the SPR values. By these functions, the SPR was adequately corrected for all U and BD data ranges. The method requires only SPR and U as input variables in the models. However, different pedofunctions are needed according to the soil layer evaluated. After adjusting the pedotransfer functions, the differences in the soil compaction levels among the treatments, previously masked by variations of U, became detectable.

Ore reserve estimation of uranium deposit Zirovski vrh

International Nuclear Information System (INIS)

Lukacs, E.

1979-01-01

The uranium ore deposit Zirovski vrh is in the Permian sediments of Northwest Yugoslavia. Lenticular bodies occur at several stratiform levels in grey, medium-grained sandstone. The ore deposit will be mined entirely by underground methods. It is possible to define three stages of deposit evaluation requiring different densities of exploration effort: preliminary evaluation of in situ ore reserves; evaluation of mineable ore reserves; evaluation of production capability and mine planning. The drilling density increases markedly with each succeeding stage. The optimal drilling density for all three stages of evaluation should be determined, but there is some concern that too close spaced drilling would considerably increase the exploration costs without a corresponding increase in effectiveness. On the other hand, too sparsely spaced drilling may result in some difficulties in following the ore in mining. The paper treats the problem of the density of drilling for evaluation of mineable ore reserves compared to that required for mine planning and mine production capability. The purpose of investigation of mineral raw materials is to define economic deposits (ore bodies). To evaluate the deposit economically an accurate reserve estimate is required. If it is accordingly established that such an estimate is within the degree of admissible error, the purpose of the exploration is satisfied. However, the problem as to whether the drilling grid is sufficiently dense remains, because the majority of estimates of ore reserves do not provide a measure of the reliability of the estimate. (author)

Design and implementation of land reservation system

Science.gov (United States)

Gao, Yurong; Gao, Qingqiang

2009-10-01

Land reservation is defined as a land management policy for insuring the government to control primary land market. It requires the government to obtain the land first, according to plan, by purchase, confiscation and exchanging, and then exploit and consolidate the land for reservation. Underlying this policy, it is possible for the government to satisfy and manipulate the needs of land for urban development. The author designs and develops "Land Reservation System for Eastern Lake Development District" (LRSELDD), which deals with the realistic land requirement problems in Wuhan Eastern Lake Development Districts. The LRSELDD utilizes modern technologies and solutions of computer science and GIS to process multiple source data related with land. Based on experiments on the system, this paper will first analyze workflow land reservation system and design the system structure based on its principles, then illustrate the approach of organization and management of spatial data, describe the system functions according to the characteristics of land reservation and consolidation finally. The system is running to serve for current work in Eastern Lake Development Districts. It is able to scientifically manage both current and planning land information, as well as the information about land supplying. We use the LRSELDD in our routine work, and with such information, decisions on land confiscation and allocation will be made wisely and scientifically.

What's an ARAR?exclamation point: Regulatory requirements for CERCLA remedial activities at D ampersand D sites on the Oak Ridge Reservation

International Nuclear Information System (INIS)

Houlberg, L.M.; Etnier, E.L.

1994-01-01

Many government-owned facilities that supported early nuclear energy research and defense programs have no current use and have been retired. Some of these facilities have residual radioactive or chemical contamination that require remediation. The Department of Energy (DOE) Decontamination and Decommissioning (D ampersand D) Program is responsible for managing these surplus facilities. Remedial activities for contaminated environs and inactive land-based units (e.g., landfills, surface impoundments) at the Oak Ridge Reservation (ORR) are conducted under the direction of the Environmental Restoration (ER) Program

26 CFR 1.801-4 - Life insurance reserves.

Science.gov (United States)

2010-04-01

... is claimed. However, reserves held by the company with respect to the net value of risks reinsured in..., life insurance reserves, as in the case of level premium life insurance, are held to supplement the... amount (if any) by which: (i) The present value of the future net premiums required for such contract...

Alternative measures of the Federal Reserve Banks' cost of equity capital

OpenAIRE

Barnes, Michelle L.; Lopez, Jose A.

2005-01-01

The Monetary Control Act of 1980 requires the Federal Reserve System to provide payment services to depository institutions through the twelve Federal Reserve Banks at prices that fully reflect the costs a private-sector provider would incur, including a cost of equity capital (COE). Although Fama and French (1997) conclude that COE estimates are “woefully” and “unavoidably” imprecise, the Reserve Banks require such an estimate every year. We examine several COE estimates based on the Capital...

Effects of different international fiscal systems on reserves reporting

International Nuclear Information System (INIS)

McMichael, C.L.

1996-01-01

The effects of international fiscal systems on oil and gas reserves evaluation and reporting, was reviewed. The movement in reserves estimates with changing technical, political and economic conditions, was described. Difficulties associated with the evaluation and booking of reserves is largely due to the confusing duplication of terms. For example, explorationists refer to reserves as an undrilled prospect, while engineers refer to them as producing property. The financial analyst refers to reserves of a company, while governments refer to the reserves of the country. The importance of defining reserves with full knowledge of the specific regulations that govern the reporting of reserves externally, and the internal reporting requirements for business planning purposes, was stressed. 2 refs

Naval Petroleum and Oil Shale Reserves

International Nuclear Information System (INIS)

1992-01-01

During fiscal year 1992, the reserves generated $473 million in revenues, a $181 million decrease from the fiscal year 1991 revenues, primarily due to significant decreases in oil and natural gas prices. Total costs were $200 million, resulting in net cash flow of $273 million, compared with $454 million in fiscal year 1991. From 1976 through fiscal year 1992, the Naval Petroleum and Oil Shale Reserves generated more than $15 billion in revenues and a net operating income after costs of $12.5 billion. In fiscal year 1992, production at the Naval Petroleum Reserves at maximum efficient rates yielded 26 million barrels of crude oil, 119 billion cubic feet of natural gas, and 164 million gallons of natural gas liquids. From April to November 1992, senior managers from the Naval Petroleum and Oil Shale Reserves held a series of three workshops in Boulder, Colorado, in order to build a comprehensive Strategic Plan as required by Secretary of Energy Notice 25A-91. Other highlights are presented for the following: Naval Petroleum Reserve No. 1--production achievements, crude oil shipments to the strategic petroleum reserve, horizontal drilling, shallow oil zone gas injection project, environment and safety, and vanpool program; Naval Petroleum Reserve No. 2--new management and operating contractor and exploration drilling; Naval Petroleum Reserve No. 3--steamflood; Naval Oil Shale Reserves--protection program; and Tiger Team environmental assessment of the Naval Petroleum and Oil Shale Reserves in Colorado, Utah, and Wyoming

32 CFR 644.86 - Exceptions and reservations.

Science.gov (United States)

2010-07-01

... roads, public highways, public utilities, railroads and pipelines,” and “to the reservations, exceptions... or District Engineer, such as requirement to install the pipeline underground and at a specified...

Objective Identification of Prepubertal Female Singers and Non-singers by Singing Power Ratio Using Matlab.

Science.gov (United States)

Usha, M; Geetha, Y V; Darshan, Y S

2017-03-01

The field of music is increasingly gaining scope and attracting researchers from varied fields in terms of improvising the art of voice modulation in singing. There has been a lot of competition, and young budding singers are emerging with more talent. This study is aimed to develop software to differentiate a prepubertal voice as that of a singer or a non-singer using an objective tool-singing power ratio (SPR)-as an objective measure to quantify the resonant voice quality. Recordings of singing and phonation were obtained from 30 singers and 30 non-singer girls (8-10 years). Three professional singers perceptually evaluated all samples using a rating scale and categorized them as singers or non-singers. Using Matlab, a program was developed to automatically calculate the SPR of a particular sample and classify it into either of two groups based on the normative values of SPR developed manually. Positive correlation for SPR of phonation or singing was found between perceptual and manual ratings, and objective values of SPR. Software could automatically give the SPR values for samples that are fed and could further differentiate them as singer or non-singer. Researchers need not depend on professional singers or musicians for the judgment of voice for research purposes. This software uses an objective tool, which serves as an instrument to judge singing talent using singing and phonation samples of children. Also, it can be used as a first line of judgment in any singing audition process, which could ease the work of professionals. Copyright © 2017 The Voice Foundation. All rights reserved.

Interactions between the German Electricity Spot Market and the Reserve Energy Market

International Nuclear Information System (INIS)

Graeber, Bernhardt

2005-01-01

Eight years after market opening, Germany has well established spot and future markets for electricity. Besides OTC and Internet broker platforms the main market place is the European Energy Exchange in Leipzig (EEX) with its spot and future market. Less known is the reserve energy market in Germany. The four German transmission system operators (TSOs) EnBW, EON, RWE and Vattenfall purchase network services on the reserve energy market. Products with specific technical requirements are primary, secondary and tertiary reserve. (Details about the technical requirements and typical means for providing the required services will be presented.) Each TSO organises a separate auction for these products - for primary and secondary reserve half-yearly, for tertiary reserve daily. Due to the technical requirements the liquidity on these markets is limited, but especially on the tertiary reserve market it is recently growing significantly due to new participants marketing several smaller municipal and industrial reserve power plants as combined bids which meet the 30 MW min. capacity requirement. Every power plant or interruptible load could not only be offered as capacity on the reserve market but could also be dispatched for the spot market. Therefore the developments of prices on these markets are not independent and opportunity costs against the spot market can be estimated for different type of plants bidding in the reserve market. Another interaction between reserve and spot market is caused by the balancing price system in Germany. Prices for balancing energy meeting deviations between load, trading balance and production of a market participant are based on quarter-hourly reserve energy costs encountered by the TSO. As unbiased load and production forecasts are not strictly enforced by the TSOs so far, part of the planned demand could be met with balancing energy if EEX spot market prices rise above expected balancing energy prices. This interrelationship has a

Joint energy and spinning reserve dispatching and pricing

International Nuclear Information System (INIS)

Rashidinejad, M.; Song, Y.-H.; Javidi Dasht-Bayaz, M.H.

2000-01-01

Unpredictable load demand variations, and also sudden generation interruption, may cause imbalance in power systems. To prevent any blackout and to reduce such total power imbalance, spinning reserve can provide electric power system ability to respond. Adequate amount of spinning reserve should be based on economy and risk as an optimal decision making. This paper uses Quadratic Programming (QP) method to solve Joint Energy and Spinning Reserve Dispatch (JESRD) problem and derives the optimal price of spinning reserve. In JESRD, Unserved Energy Cost (UEC) is considered as an Opportunity Cost of Spinning Reserve (OCSR). To distribute the System Reserve Requirements (SRR) among generation units, two different models, Fixed Reserve Percentage (FRP) or fixed allocation model and Non-Fixed Reserve Percentage (NFRP) or flexible allocation model has been investigated. Numerical results on a 5-bus test system and the 30-bus IEEE standard system, considering FRP and NFRP models are included. (author)

Compliance with the Clean Air Act Title VI Stratospheric Ozone Protection Program requirements at U.S. DOE Oak Ridge Reservation Facilities

International Nuclear Information System (INIS)

Humphreys, M.P.; Atkins, E.M.

1999-01-01

The Title VI Stratospheric Ozone Protection Program of the Clean Air Act (CAA) requires promulgation of regulations to reduce and prevent damage to the earth's protective ozone layer. Regulations pursuant to Title VI of the CAA are promulgated in the Code of Federal Regulations (CFR) at Title 40 CFR, Part 822. The regulations include ambitious production phaseout schedules for ozone depleting substances (ODS) including chlorofluorocarbons (CFCs), hydrochlorofluorocarbons (HCFCs), halons, carbon tetrachloride, and methyl chloroform under 40 CFR 82, Subpart A. The regulations also include requirements for recycling and emissions reduction during the servicing of refrigeration equipment and technician certification requirements under Subpart F; provisions for servicing of motor vehicle air conditioners under Subpart B; a ban on nonessential products containing Class 1 ODS under Subpart C; restrictions on Federal procurement of ODS under Subpart D; labeling of products using ODS under Subpart E; and the Significant New Alternatives Policy Program under Subpart G. This paper will provide details of initiatives undertaken at US Department of Energy (DOE) Oak Ridge Reservation (ORR) Facilities for implementation of requirements under the Title VI Stratospheric Ozone Protection Program. The Stratospheric Ozone Protection Plans include internal DOE requirements for: (1) maintenance of ODS inventories; (2) ODS procurement practices; (3) servicing of refrigeration and air conditioning equipment; (4) required equipment modifications or replacement; (5) technician certification training; (6) labeling of products containing ODS; (7) substitution of chlorinated solvents; and (8) replacement of halon fire protection systems. The plans also require establishment of administrative control systems which assure that compliance is achieved and maintained as the regulations continue to develop and become effective

Lithium reserves and resources

International Nuclear Information System (INIS)

Evans, R.K.

1978-01-01

As a result of accelerating research efforts in the fields of secondary batteries and thermonuclear power generation, concern has been expressed in certain quarters regarding the availability, in sufficient quantities, of lithium. As part of a recent study by the National Research Council on behalf of the Energy Research and Development Administration, a subpanel was formed to consider the outlook for lithium. Principal areas of concern were reserves, resources and the 'surplus' available for energy applications after allowing for the growth in current lithium applications. Reserves and resources were categorized into four classes ranging from fully proved reserves to resources which are probably dependent upon the marketing of co-products to become economically attractive. Because of the proprietary nature of data on beneficiation and processing recoveries, the tonnages of available lithium are expressed in terms of plant feed. However, highly conservative assumptions have been made concerning mining recoveries and these go a considerable way to accounting for total losses. Western World reserves and resources of all classes are estimated at 10.6 million tonnes Li of which 3.5 million tonnes Li are located in the United States. Current United States capacity, virtually equivalent to Western World capacity, is 4700 tonnes Li and production in 1976 approximated to 3500 tonnes Li. Production for current applications is expected to grow to approx. 10,000 tonnes in year 2000 and 13,000 tonnes a decade later. The massive excess of reserves and resources over that necessary to support conventional requirements has limited the amount of justifiable exploration expenditures; on the last occasion, there was a a major increase in demand (by the USAEA) reserves and capacity were increased rapidly. There are no foreseeable reasons why this shouldn't happen again when the need is clear. (author)

Kinematics and dynamics analysis of a novel serial-parallel dynamic simulator

Energy Technology Data Exchange (ETDEWEB)

Hu, Bo; Zhang, Lian Dong; Yu, Jingjing [Parallel Robot and Mechatronic System Laboratory of Hebei Province, Yanshan University, Qinhuangdao, Hebei (China)

2016-11-15

A serial-parallel dynamics simulator based on serial-parallel manipulator is proposed. According to the dynamics simulator motion requirement, the proposed serial-parallel dynamics simulator formed by 3-RRS (active revolute joint-revolute joint-spherical joint) and 3-SPR (Spherical joint-active prismatic joint-revolute joint) PMs adopts the outer and inner layout. By integrating the kinematics, constraint and coupling information of the 3-RRS and 3-SPR PMs into the serial-parallel manipulator, the inverse Jacobian matrix, velocity, and acceleration of the serial-parallel dynamics simulator are studied. Based on the principle of virtual work and the kinematics model, the inverse dynamic model is established. Finally, the workspace of the (3-RRS)+(3-SPR) dynamics simulator is constructed.

Scaling of the Surface Plasmon Resonance in Gold and Silver Dimers Probed by EELS

DEFF Research Database (Denmark)

Kadkhodazadeh, Shima; de Lasson, Jakob Rosenkrantz; Beleggia, Marco

2014-01-01

The dependence of surface plasmon coupling on the distance between two nanoparticles (dimer) is the basis of nanometrology tools such as plasmon rulers. Application of these nanometric rulers requires an accurate description of the scaling of the surface plasmon resonance (SPR) wavelength...... with distance. Here, we have applied electron energy-loss spectroscopy (EELS) and scanning transmission electron microscopy (STEM) imaging to investigate the relationship between the SPR wavelength of gold and silver nanosphere dimers (radius R) and interparticle distance (d) in the range 0.1R .... Instead, within the range 0.1R gold and silver dimers. Despite this common power dependence, consistently larger SPR wavelength shifts are registered for silver for a given change in d, implying...

Kinematics and dynamics analysis of a novel serial-parallel dynamic simulator

International Nuclear Information System (INIS)

Hu, Bo; Zhang, Lian Dong; Yu, Jingjing

2016-01-01

A serial-parallel dynamics simulator based on serial-parallel manipulator is proposed. According to the dynamics simulator motion requirement, the proposed serial-parallel dynamics simulator formed by 3-RRS (active revolute joint-revolute joint-spherical joint) and 3-SPR (Spherical joint-active prismatic joint-revolute joint) PMs adopts the outer and inner layout. By integrating the kinematics, constraint and coupling information of the 3-RRS and 3-SPR PMs into the serial-parallel manipulator, the inverse Jacobian matrix, velocity, and acceleration of the serial-parallel dynamics simulator are studied. Based on the principle of virtual work and the kinematics model, the inverse dynamic model is established. Finally, the workspace of the (3-RRS)+(3-SPR) dynamics simulator is constructed

Heuristic Optimization Techniques for Determining Optimal Reserve Structure of Power Generating Systems

DEFF Research Database (Denmark)

Ding, Yi; Goel, Lalit; Wang, Peng

2012-01-01

cost of the system will also increase. The reserve structure of a MSS should be determined based on striking a balance between the required reliability and the reserve cost. The objective of reserve management for a MSS is to schedule the reserve at the minimum system reserve cost while maintaining......Electric power generating systems are typical examples of multi-state systems (MSS). Sufficient reserve is critically important for maintaining generating system reliabilities. The reliability of a system can be increased by increasing the reserve capacity, noting that at the same time the reserve...... the required level of supply reliability to its customers. In previous research, Genetic Algorithm (GA) has been used to solve most reliability optimization problems. However, the GA is not very computationally efficient in some cases. In this chapter a new heuristic optimization technique—the particle swarm...

40 CFR 80.575-80.579 - [Reserved

Science.gov (United States)

2010-07-01

... (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Motor Vehicle Diesel Fuel; Nonroad, Locomotive, and Marine Diesel Fuel; and ECA Marine Fuel Labeling Requirements §§ 80.575-80.579 [Reserved] Sampling and Testing ...

12 CFR 204.135 - Shifting funds between depository institutions to make use of the low reserve tranche.

Science.gov (United States)

2010-01-01

... SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM RESERVE REQUIREMENTS OF DEPOSITORY INSTITUTIONS... prevent evasions of the requirements of that section. Section 19(b)(2) establishes general reserve... that is exempt from transaction account reserve requirements. [57 FR 38429, Aug. 25, 1992] ...

Adequacy of Frequency Reserves for High Wind Power Generation

DEFF Research Database (Denmark)

Das, Kaushik; Litong-Palima, Marisciel; Maule, Petr

2017-01-01

In this article, a new methodology is developed to assess the adequacy of frequency reserves to handle power imbalances caused by wind power forecast errors. The goal of this methodology is to estimate the adequate volume and speed of activation of frequency reserves required to handle power...

Investigação numérica do desempenho de um sensor de fibra ótica de índice de refração, baseado em SPR e utilizando COMSOL multiphysics

OpenAIRE

Santos, Diego Felipe de Nóbrega dos

2013-01-01

Esta tese é dedicada aos sensores de fibra ótica especificamente aos sensores baseados no fenómeno de ressonância de plasmão de superfície, SPR (Surface Plasmon Resonance), gerados em fibras óticas com configuração do tipo “D”, para aplicação em sensores refratométricos. Numa primeira parte desta dissertação são descritos os aspetos teóricos fundamentais para a compreensão dos fenómenos de ressonância de plasmões de superfície e a sua utilização em sistemas sensores. Estes f...

40 CFR 112.13-112.15 - [Reserved

Science.gov (United States)

2010-07-01

... POLLUTION PREVENTION Requirements for Animal Fats and Oils and Greases, and Fish and Marine Mammal Oils; and for Vegetable Oils, including Oils from Seeds, Nuts, Fruits, and Kernels. §§ 112.13-112.15 [Reserved] ...

CBM Resources/reserves classification and evaluation based on PRMS rules

Science.gov (United States)

Fa, Guifang; Yuan, Ruie; Wang, Zuoqian; Lan, Jun; Zhao, Jian; Xia, Mingjun; Cai, Dechao; Yi, Yanjing

2018-02-01

This paper introduces a set of definitions and classification requirements for coalbed methane (CBM) resources/reserves, based on Petroleum Resources Management System (PRMS). The basic CBM classification criterions of 1P, 2P, 3P and contingent resources are put forward from the following aspects: ownership, project maturity, drilling requirements, testing requirements, economic requirements, infrastructure and market, timing of production and development, and so on. The volumetric method is used to evaluate the OGIP, with focuses on analyses of key parameters and principles of the parameter selection, such as net thickness, ash and water content, coal rank and composition, coal density, cleat volume and saturation and absorbed gas content etc. A dynamic method is used to assess the reserves and recovery efficiency. Since the differences in rock and fluid properties, displacement mechanism, completion and operating practices and wellbore type resulted in different production curve characteristics, the factors affecting production behavior, the dewatering period, pressure build-up and interference effects were analyzed. The conclusion and results that the paper achieved can be used as important references for reasonable assessment of CBM resources/reserves.

Visual and surface plasmon resonance sensor for zirconium based on zirconium-induced aggregation of adenosine triphosphate-stabilized gold nanoparticles.

Science.gov (United States)

Qi, Wenjing; Zhao, Jianming; Zhang, Wei; Liu, Zhongyuan; Xu, Min; Anjum, Saima; Majeed, Saadat; Xu, Guobao

2013-07-17

Owing to its high affinity with phosphate, Zr(IV) can induce the aggregation of adenosine 5'-triphosphate (ATP)-stabilized AuNPs, leading to the change of surface plasmon resonance (SPR) absorption spectra and color of ATP-stabilized AuNP solutions. Based on these phenomena, visual and SPR sensors for Zr(IV) have been developed for the first time. The A(660 nm)/A(518 nm) values of ATP-stabilized AuNPs in SPR absorption spectra increase linearly with the concentrations of Zr(IV) from 0.5 μM to 100 μM (r=0.9971) with a detection limit of 95 nM. A visual Zr(IV) detection is achieved with a detection limit of 30 μM. The sensor shows excellent selectivity against other metal ions, such as Cu(2+), Fe(3+), Cd(2+), and Pb(2+). The recoveries for the detection of 5 μM, 10 μM, 25 μM and 75 μM Zr(IV) in lake water samples are 96.0%, 97.0%, 95.6% and 102.4%, respectively. The recoveries of the proposed SPR method are comparable with those of ICP-OES method. Copyright © 2013 Elsevier B.V. All rights reserved.

A Flexible Reservation Algorithm for Advance Network Provisioning

Energy Technology Data Exchange (ETDEWEB)

Balman, Mehmet; Chaniotakis, Evangelos; Shoshani, Arie; Sim, Alex

2010-04-12

Many scientific applications need support from a communication infrastructure that provides predictable performance, which requires effective algorithms for bandwidth reservations. Network reservation systems such as ESnet's OSCARS, establish guaranteed bandwidth of secure virtual circuits for a certain bandwidth and length of time. However, users currently cannot inquire about bandwidth availability, nor have alternative suggestions when reservation requests fail. In general, the number of reservation options is exponential with the number of nodes n, and current reservation commitments. We present a novel approach for path finding in time-dependent networks taking advantage of user-provided parameters of total volume and time constraints, which produces options for earliest completion and shortest duration. The theoretical complexity is only O(n2r2) in the worst-case, where r is the number of reservations in the desired time interval. We have implemented our algorithm and developed efficient methodologies for incorporation into network reservation frameworks. Performance measurements confirm the theoretical predictions.

7 CFR 3560.306 - Reserve account.

Science.gov (United States)

2010-01-01

... be deemed to contain surplus funds when the balance at the end of the housing project's fiscal year...) As projects age, the required reserve account level may be adjusted to meet anticipated “life-cycle..., identity-of-interest, cost-reasonableness, and construction management apply to any work or services paid...

Pr{sub 3}S{sub 2}Cl{sub 2}[AsS{sub 3}]: a praseodymium(III) sulfide chloride thioarsenate(III) with double chains of condensed [SPr{sub 4}]{sup 10+} tetrahedra

Energy Technology Data Exchange (ETDEWEB)

Kang, Dong-Hee [Institute for Inorganic Chemistry, University of Stuttgart (Germany); Department of Chemistry, University of Waterloo, ON (Canada); Korea Research Institute of Standards and Science (KRISS), Daejeon (Korea, Republic of); Ledderboge, Florian; Schleid, Thomas [Institute for Inorganic Chemistry, University of Stuttgart (Germany); Kleinke, Holger [Department of Chemistry, University of Waterloo, ON (Canada)

2015-02-15

Single crystals of Pr{sub 3}S{sub 2}Cl{sub 2}[AsS{sub 3}] were obtained by reacting praseodymium sesquisulfide and trichloride with arsenic and sulfur (molar ratio: 7:4:6:9) in torch-sealed evacuated silica ampoules at 850 C for a week and subsequent slow cooling to room temperature. The transparent, pale yellowish green platelets crystallize monoclinically (Pr{sub 3}S{sub 2}Cl{sub 2}[AsS{sub 3}]: a = 2190.96(9) pm, b = 685.49(3) pm, c = 701.87(3) pm, β = 98.752(3) ) in the non-centrosymmetric space group Cc with Z = 4. The crystal structure of Pr{sub 3}S{sub 2}Cl{sub 2}[AsS{sub 3}] comprises three crystallographically different Pr{sup 3+} cations. (Pr1){sup 3+} and (Pr2){sup 3+} exhibit bicapped trigonal prismatic environments of five sulfur and three chlorine atoms (C.N. = 8) each, whereas only seven sulfur atoms arranged as capped trigonal prism (C.N. = 7) are present in the case of (Pr3){sup 3+}. Two of the five crystallographically different sulfur atoms (S1 and S2) are coordinated by four Pr{sup 3+} cations, each in the shape of slightly distorted [SPr{sub 4}]{sup 10+} tetrahedra (d(S-Pr) = 278-294 pm). Hence, the crystal structure of Pr{sub 3}S{sub 2}Cl{sub 2}[AsS{sub 3}] contains double chains with the composition {sup 1}{sub ∞}{[S_2Pr_3]"5"+}, consisting of two parallel edge-fused chains of anti-SiS{sub 2}-analogous single strands {sup 1}{sub ∞}{[SPr_2]"4"+}, formed by trans-edge sharing [SPr{sub 4}]{sup 10+} tetrahedra. The arrangement of the {sup 1}{sub ∞}{[S_2Pr_3]"5"+} double chains running along [001] can be described as a hexagonal rod-packing. Chloride anions (Cl1 and Cl2) as well as the isolated, ψ{sup 1}-tetrahedral thioarsenate(III) groups [AsS{sub 3}]{sup 3-} (d(As-S) = 228-229 pm) consisting of three sulfur atoms (S3, S4, and S5) and an As{sup 3+} cation carrying a stereochemically active non-bonding electron pair take care of the three-dimensional interconnection and the charge balance of the {sup 1}{sub ∞}{[S_2Pr_3]"5"+} double

12 CFR 204.136 - Treatment of trust overdrafts for reserve requirement reporting purposes.

Science.gov (United States)

2010-01-01

... accounts under Regulation D. Unless the governing trust agreement or state law authorizes the depository... pursuant to trust law or written agreement, or where the amount that caused the overdraft is still... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Treatment of trust overdrafts for reserve...

Reserves reporting for decision-making planning and control

International Nuclear Information System (INIS)

Higgins, G.

1992-01-01

This paper shows how the established Monte Carlo simulation approach to estimating hydrocarbon reserves can be expanded to provide the basis of a comprehensive valuation, planning and control system meeting all the reserve reporting requirements of an oil exploration and production company. The approach presented is also appropriate for other mining and extractive industries. The paper demonstrates how individual expectation curves can be modified to reflect both technically and commercially recoverable reserves and how these are in turn combined into the economic valuation, planning and control processes of an enterprise. Estimates across the full range of risk and reserves can be aggregated to provide a powerful planning tool that can be used to set corporate, divisional and individual objectives

Geomechanical testing of Bayou Choctaw 102B core for SPR analysis

Energy Technology Data Exchange (ETDEWEB)

Ingraham, Mathew Duffy; Broome, Scott Thomas; Bauer, Stephen J.; Barrow, Perry Carl; Flint, Gregory Mark.

2014-02-01

A laboratory testing program was developed to examine the short-term mechanical and time-dependent (creep) behavior of salt from the Bayou Choctaw Salt Dome. This report documents the test methodologies, and constitutive properties inferred from tests performed. These are used to extend our understanding of the mechanical behavior of the Bayou Choctaw domal salt and provide a data set for numerical analyses. The resulting information will be used to support numerical analyses of the current state of the Bayou Choctaw Dome as it relates to its crude oil storage function as part of the US Strategic Petroleum Reserve. Core obtained from Drill Hole BC-102B was tested under creep and quasi-static constant mean stress axisymmetric compression, and constant mean stress axisymmetric extension conditions. Creep tests were performed at 100 degrees Fahrenheit, and the axisymmetric tests were performed at ambient temperatures (72-78 degrees Fahrenheit). The testing performed indicates that the dilation criterion is pressure and stress state dependent. It was found that as the mean stress increases, the shear stress required to cause dilation increases. The results for this salt are reasonably consistent with those observed for other domal salts. Also it was observed that tests performed under extensile conditions required consistently lower shear stress to cause dilation for the same mean stress, which is consistent with other domal salts. Young's moduli ranged from 3.95 x 10⁶ to 8.51 x 10⁶ psi with an average of 6.44 x 10⁶ psi, with Poisson's ratios ranging from 0.10 to 0.43 with an average of 0.30. Creep testing indicates that the BC salt is intermediate in creep resistance when compared with other bedded and domal salt steady-state behavior.

High-resolution paleoclimatology of the Santa Barbara Basin during the Medieval Climate Anomaly and early Little Ice Age based on diatom and silicoflagellate assemblages in Kasten core SPR0901-02KC

Science.gov (United States)

Barron, John A.; Bukry, David B.; Hendy, Ingrid L.

2015-01-01

Diatom and silicoflagellate assemblages documented in a high-resolution time series spanning 800 to 1600 AD in varved sediment recovered in Kasten core SPR0901-02KC (34°16.845’ N, 120°02.332’ W, water depth 588 m) from the Santa Barbara Basin (SBB) reveal that SBB surface water conditions during the Medieval Climate Anomaly (MCA) and the early part of the Little Ice Age (LIA) were not extreme by modern standards, mostly falling within one standard deviation of mean conditions during the pre anthropogenic interval of 1748 to 1900. No clear differences between the character of MCA and the early LIA conditions are apparent. During intervals of extreme droughts identified by terrigenous proxy scanning XRF analyses, diatom and silicoflagellate proxies for coastal upwelling typically exceed one standard deviation above mean values for 1748-1900, supporting the hypothesis that droughts in southern California are associated with cooler (or La Niña-like) sea surface temperatures (SSTs). Increased percentages of diatoms transported downslope generally coincide with intervals of increased siliciclastic flux to the SBB identified by scanning XRF analyses. Diatom assemblages suggest only two intervals of the MCA (at ~897 to 922 and ~1151 to 1167) when proxy SSTs exceeded one standard deviation above mean values for 1748 to 1900. Conversely, silicoflagellates imply extreme warm water events only at ~830 to 860 (early MCA) and ~1360 to 1370 (early LIA) that are not supported by the diatom data. Silicoflagellates appear to be more suitable for characterizing average climate during the 5 to 11 year-long sample intervals studied in the SPR0901-02KC core than diatoms, probably because diatom relative abundances may be dominated by seasonal blooms of a particular year.

Designing connected marine reserves in the face of global warming.

Science.gov (United States)

Álvarez-Romero, Jorge G; Munguía-Vega, Adrián; Beger, Maria; Del Mar Mancha-Cisneros, Maria; Suárez-Castillo, Alvin N; Gurney, Georgina G; Pressey, Robert L; Gerber, Leah R; Morzaria-Luna, Hem Nalini; Reyes-Bonilla, Héctor; Adams, Vanessa M; Kolb, Melanie; Graham, Erin M; VanDerWal, Jeremy; Castillo-López, Alejandro; Hinojosa-Arango, Gustavo; Petatán-Ramírez, David; Moreno-Baez, Marcia; Godínez-Reyes, Carlos R; Torre, Jorge

2018-02-01

Marine reserves are widely used to protect species important for conservation and fisheries and to help maintain ecological processes that sustain their populations, including recruitment and dispersal. Achieving these goals requires well-connected networks of marine reserves that maximize larval connectivity, thus allowing exchanges between populations and recolonization after local disturbances. However, global warming can disrupt connectivity by shortening potential dispersal pathways through changes in larval physiology. These changes can compromise the performance of marine reserve networks, thus requiring adjusting their design to account for ocean warming. To date, empirical approaches to marine prioritization have not considered larval connectivity as affected by global warming. Here, we develop a framework for designing marine reserve networks that integrates graph theory and changes in larval connectivity due to potential reductions in planktonic larval duration (PLD) associated with ocean warming, given current socioeconomic constraints. Using the Gulf of California as case study, we assess the benefits and costs of adjusting networks to account for connectivity, with and without ocean warming. We compare reserve networks designed to achieve representation of species and ecosystems with networks designed to also maximize connectivity under current and future ocean-warming scenarios. Our results indicate that current larval connectivity could be reduced significantly under ocean warming because of shortened PLDs. Given the potential changes in connectivity, we show that our graph-theoretical approach based on centrality (eigenvector and distance-weighted fragmentation) of habitat patches can help design better-connected marine reserve networks for the future with equivalent costs. We found that maintaining dispersal connectivity incidentally through representation-only reserve design is unlikely, particularly in regions with strong asymmetric patterns of

JAK/STAT-1 Signaling Is Required for Reserve Intestinal Stem Cell Activation during Intestinal Regeneration Following Acute Inflammation

Directory of Open Access Journals (Sweden)

Camilla A. Richmond

2018-01-01

Full Text Available The intestinal epithelium serves as an essential barrier to the outside world and is maintained by functionally distinct populations of rapidly cycling intestinal stem cells (CBC ISCs and slowly cycling, reserve ISCs (r-ISCs. Because disruptions in the epithelial barrier can result from pathological activation of the immune system, we sought to investigate the impact of inflammation on ISC behavior during the regenerative response. In a murine model of αCD3 antibody-induced small-intestinal inflammation, r-ISCs proved highly resistant to injury, while CBC ISCs underwent apoptosis. Moreover, r-ISCs were induced to proliferate and functionally contribute to intestinal regeneration. Further analysis revealed that the inflammatory cytokines interferon gamma and tumor necrosis factor alpha led to r-ISC activation in enteroid culture, which could be blocked by the JAK/STAT inhibitor, tofacitinib. These results highlight an important role for r-ISCs in response to acute intestinal inflammation and show that JAK/STAT-1 signaling is required for the r-ISC regenerative response.

Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?

DEFF Research Database (Denmark)

Hansen, Thomas Lau; Rasmussen, Lene Juel; Madsen, Claus Desler

2012-01-01

Oxidative phosphorylation is an indispensable resource of ATP in tissues with high requirement of energy. If the ATP demand is not met, studies suggest that this will lead to senescence and cell death in the affected tissue. The term reserve respiratory capacity or spare respiratory capacity...... is used to describe the amount of extra ATP that can be produced by oxidative phosphorylation in case of a sudden increase in energy demand. Depletion of the reserve respiratory capacity has been related to a range of pathologies affecting high energy requiring tissues. During aging of an organism......, and as a result of mitochondrial dysfunctions, the efficiency of oxidative phosphorylation declines. Based on examples from the energy requiring tissues such as brain, heart, and skeletal muscle, we propose that the age-related decline of oxidative phosphorylation decreases the reserve respiratory capacity...

22 CFR 226.1003 - Air transportation. [Reserved

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Air transportation. [Reserved] 226.1003 Section 226.1003 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF ASSISTANCE AWARDS TO U.S. NON-GOVERNMENTAL ORGANIZATIONS USAID-Specific Requirements § 226.1003 Air transportation...

Financing options to develop non-conventional reserves

International Nuclear Information System (INIS)

Tricoli, C.

1997-01-01

The economics of non-conventional natural gas reserves such as coalbed methane, gas shales and tight gas were discussed, with special reference to financing options to develop such reserves. Before 1992, tax credits were used to stimulate the development of non-conventional gas. The requirements for section 29 tax credits, the objectives of investors and producers, and the methods used to monetize section 29 tax credits, such as public royalty trusts, partnership structures, and up-front payment mechanisms were described. The capital gains implications of gas sales were also reviewed. It was noted that in the absence of tax credits, financing the development of non-conventional reserves must undergo the same economic scrutiny as any other oil and gas project

Integrating nanohybrid membranes of reduced graphene oxide: chitosan: silica sol gel with fiber optic SPR for caffeine detection

Science.gov (United States)

Kant, Ravi; Tabassum, Rana; Gupta, Banshi D.

2017-05-01

Caffeine is the most popular psychoactive drug consumed in the world for improving alertness and enhancing wakefulness. However, caffeine consumption beyond limits can result in lot of physiological complications in human beings. In this work, we report a novel detection scheme for caffeine integrating nanohybrid membranes of reduced graphene oxide (rGO) in chitosan modified silica sol gel (rGO: chitosan: silica sol gel) with fiber optic surface plasmon resonance. The chemically synthesized nanohybrid membrane forming the sensing route has been dip coated over silver coated unclad central portion of an optical fiber. The sensor works on the mechanism of modification of dielectric function of sensing layer on exposure to analyte solution which is manifested in terms of red shift in resonance wavelength. The concentration of rGO in polymer network of chitosan and silica sol gel and dipping time of the silver coated probe in the solution of nanohybrid membrane have been optimized to extricate the supreme performance of the sensor. The optimized sensing probe possesses a reasonably good sensitivity and follows an exponentially declining trend within the entire investigating range of caffeine concentration. The sensor boasts of an unparalleled limit of detection value of 1.994 nM and works well in concentration range of 0-500 nM with a response time of 16 s. The impeccable sensor methodology adopted in this work combining fiber optic SPR with nanotechnology furnishes a novel perspective for caffeine determination in commercial foodstuffs and biological fluids.

Assessment of the relationship between oil prices and US oil stocks

International Nuclear Information System (INIS)

Saif Ghouri, Salman

2006-01-01

This paper qualitatively and quantitatively analyzes the relationship between US monthly ending oil stocks position with that of West Texas Intermediate (WTI) oil prices from February 1995 to July 2004. The paper concludes if other things are held constant, WTI is inversely related to the petroleum products (PPP), combined petroleum products and crude oil (CPPP), crude oil alone (Crude), total oil stocks including petroleum products, crude oil and strategic petroleum reserves SPR (Total), total gasoline (TGO), total distillate (TDO). It could not establish a statistically significant and negative relationship with SPR when run alone. One percent increase (decrease) in CPPP, PPP, Crude, Total, TGO and TDO leads to decrease (increase) in WTI, respectively, by 0.70, 0.43, 0.37, 0.97, 0.26 and 0.21 percent. Oil prices are largely influenced by total crude and Crude and PPP inventories levels while modestly with variations in gasoline and distillate stocks levels. Despite a healthy increase of over 22 percent in SPR from January 2001 to April 2004, it did not result in easing of oil prices. Primarily because SPR are meant for security of supply concern and are only released under extreme conditions by the President of United States, they are neither meant for the purposes of balancing supply-demand gap nor for the stability of oil prices. The aggressive SPR buildup in recent years is related to international terrorism, geopolitical situation in the Middle East, particularly in Iraq, that encourages US government to enhance its SPR to meet any short-term eventuality. The analyst must keep a close eye on CPPP and the total oil stocks variation to forecast WTI in the short run whilst gasoline and distillate influence oil prices modestly in the short run. SPR, on the other hand, are expected to play a pivotal role in balancing oil prices and in providing a critical resource for the economy in case of any major shortfall in the long run

Assessment of the relationship between oil prices and US oil stocks

Energy Technology Data Exchange (ETDEWEB)

Saif Ghouri, Salman [Business Environment Section, Corporate Planning Department, Qatar Petroleum, Doha (Qatar)]. E-mail: ghouri@qp.com.qa

2006-11-15

This paper qualitatively and quantitatively analyzes the relationship between US monthly ending oil stocks position with that of West Texas Intermediate (WTI) oil prices from February 1995 to July 2004. The paper concludes if other things are held constant, WTI is inversely related to the petroleum products (PPP), combined petroleum products and crude oil (CPPP), crude oil alone (Crude), total oil stocks including petroleum products, crude oil and strategic petroleum reserves SPR (Total), total gasoline (TGO), total distillate (TDO). It could not establish a statistically significant and negative relationship with SPR when run alone. One percent increase (decrease) in CPPP, PPP, Crude, Total, TGO and TDO leads to decrease (increase) in WTI, respectively, by 0.70, 0.43, 0.37, 0.97, 0.26 and 0.21 percent. Oil prices are largely influenced by total crude and Crude and PPP inventories levels while modestly with variations in gasoline and distillate stocks levels. Despite a healthy increase of over 22 percent in SPR from January 2001 to April 2004, it did not result in easing of oil prices. Primarily because SPR are meant for security of supply concern and are only released under extreme conditions by the President of United States, they are neither meant for the purposes of balancing supply-demand gap nor for the stability of oil prices. The aggressive SPR buildup in recent years is related to international terrorism, geopolitical situation in the Middle East, particularly in Iraq, that encourages US government to enhance its SPR to meet any short-term eventuality. The analyst must keep a close eye on CPPP and the total oil stocks variation to forecast WTI in the short run whilst gasoline and distillate influence oil prices modestly in the short run. SPR, on the other hand, are expected to play a pivotal role in balancing oil prices and in providing a critical resource for the economy in case of any major shortfall in the long run.

Sequence Classification: 891809 [

Lifescience Database Archive (English)

Full Text Available unknown function, expressed during sporulation; not required for sporulation, but gene exhibits genetic int...eractions with other genes required for sporulation; Spr6p || http://www.ncbi.nlm.nih.gov/protein/6320961 ...

The Screw-Like Movement of a Gliding Bacterium Is Powered by Spiral Motion of Cell-Surface Adhesins.

Science.gov (United States)

Shrivastava, Abhishek; Roland, Thibault; Berg, Howard C

2016-09-06

Flavobacterium johnsoniae, a rod-shaped bacterium, glides over surfaces at speeds of ∼2 μm/s. The propulsion of a cell-surface adhesin, SprB, is known to enable gliding. We used cephalexin to generate elongated cells with irregular shapes and followed their displacement in three dimensions. These cells rolled about their long axes as they moved forward, following a right-handed trajectory. We coated gold nanoparticles with an SprB antibody and tracked them in three dimensions in an evanescent field where the nanoparticles appeared brighter when they were closer to the glass. The nanoparticles followed a right-handed spiral trajectory on the surface of the cell. Thus, if SprB were to adhere to the glass rather than to a nanoparticle, the cell would move forward along a right-handed trajectory, as observed, but in a direction opposite to that of the nanoparticle. Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Development of surface plasmon resonance sensor for determining zinc ion using novel active nanolayers as probe.

Science.gov (United States)

Fen, Yap Wing; Yunus, W Mahmood Mat; Talib, Zainal Abidin; Yusof, Nor Azah

2015-01-05

In this study, novel active nanolayers in combination with surface plasmon resonance (SPR) system for zinc ion (Zn(2+)) detection has been developed. The gold surface used for the SPR system was modified with the novel developed active nanolayers, i.e. chitosan and chitosan-tetrabutyl thiuram disulfide (chitosan-TBTDS). Both chitosan and chitosan-TBTDS active layers were fabricated on the gold surface by spin coating technique. The system was used to monitor SPR signal for Zn(2+) in aqueous media with and without sensitivity enhancement by TBTDS. For both active nanolayers, the shift of resonance angle is directly proportional to the concentration of Zn(2+) in aqueous media. The higher shift of resonance angle was obtained for chitosan-TBTDS active nanolayer due to a specific binding of TBTDS with Zn(2+). The chitosan-TBTDS active nanolayer enhanced the sensitivity of detection down to 0.1 mg/l and also induced a selective detection towards Zn(2+). Copyright © 2014 Elsevier B.V. All rights reserved.

Oak Ridge reservation, annual site environmental report summary for 1993

International Nuclear Information System (INIS)

1994-11-01

The U.S. Department of Energy requires annual site environmental reports from facilities that operate under its auspices. To fulfill that requirement, such an annual report is published for the Oak Ridge Reservation, which comprises three major sites, each of which has unique monitoring requirements in addition to many shared obligations. As a result, the report is complex and highly detailed. Annual site environmental reports are public documents that are read by government regulators, scientists, engineers, business people, special interest groups, and members of the public at large. For that reason, the reports need to be accessible to a variety of audiences in addition to being accurate and complete. This pamphlet summarizes environmental activities on the reservation, which for some readers may be adequate; for those who seek more detail, it will lend coherence to their approach to the report itself. The content of this summary was taken from Oak Ridge Reservation Annual Site Environmental Report for 1993. Results of the many environmental monitoring and surveillance activities are detailed in this report

Using stockpile delegation to improve China's strategic oil policy: A multi-dimension stochastic dynamic programming approach

International Nuclear Information System (INIS)

Chen, Xin; Mu, Hailin; Li, Huanan; Gui, Shusen

2014-01-01

There has been much attention paid to oil security in China in recent years. Although China has begun to establish its own strategic petroleum reserve (SPR) to prevent potential losses caused by oil supply interruptions, the system aiming to ensure China's oil security is still incomplete. This paper describes and provides evidence for the benefits of an auxiliary strategic oil policy choice, which aims to strengthen China's oil supply security and offer a solution for strategic oil operations with different holding costs. In this paper, we develop a multi-dimension stochastic dynamic programming model to analyze the oil stockpile delegation policy, which is an intermediate policy between public and private oil stockpiles and is appropriate for the Chinese immature private oil stockpile sector. The model examines the effects of the oil stockpile delegation policy in the context of several distinct situations, including normal world oil market conditions, slight oil supply interruption, and serious oil supply interruption. Operating strategies that respond to different oil supply situations for both the SPR and the delegated oil stockpile were obtained. Different time horizons, interruption times and holding costs of delegated oil stockpiles were examined. The construction process of China's SPR was also taken into account. - Highlights: • We provided an auxiliary strategic oil policy rooted in Chinese local conditions. • The policy strengthen China's capability for preventing oil supply interruption. • We model to obtain the managing strategies for China's strategic petroleum reserve. • Both of the public and delegated oil stockpile were taken into consideration. • The three phase's construction process of China's SPR was taken into account

Self-piercing riveting - a review\\ud

OpenAIRE

Li, Dezhi; Chrysanthou, Andreas; Patel, Imran; Williams, Geraint J.

2016-01-01

Self-Piercing Riveting (SPR) is a cold mechanical joining process used to join two or more sheets of materials by driving a semitubular rivet piercing through the top sheet or the top and middle sheets and subsequently lock into the bottom sheet under the guidance of a suitable die. SPR was originated half century ago, but it only had significant progress in the last 25 years due to the requirement of joining lightweight materials, such as aluminium alloy structures, aluminium-steel structure...

Detection of norovirus virus-like particles using a surface plasmon resonance-assisted fluoroimmunosensor optimized for quantum dot fluorescent labels.

Science.gov (United States)

Ashiba, Hiroki; Sugiyama, Yuki; Wang, Xiaomin; Shirato, Haruko; Higo-Moriguchi, Kyoko; Taniguchi, Koki; Ohki, Yoshimichi; Fujimaki, Makoto

2017-07-15

A highly sensitive biosensor to detect norovirus in environment is desired to prevent the spread of infection. In this study, we investigated a design of surface plasmon resonance (SPR)-assisted fluoroimmunosensor to increase its sensitivity and performed detection of norovirus virus-like particles (VLPs). A quantum dot fluorescent dye was employed because of its large Stokes shift. The sensor design was optimized for the CdSe-ZnS-based quantum dots. The optimal design was applied to a simple SPR-assisted fluoroimmunosensor that uses a sensor chip equipped with a V-shaped trench. Excitation efficiency of the quantum dots, degree of electric field enhancement by SPR, and intensity of autofluorescence of a substrate of the sensor chip were theoretically and experimentally evaluated to maximize the signal-to-noise ratio. As the result, an excitation wavelength of 390nm was selected to excite SPR on an Al film of the sensor chip. The sandwich assay of norovirus VLPs was performed using the designed sensor. Minimum detectable concentration of 0.01ng/mL, which corresponds to 100 virus-like particles included in the detection region of the V-trench, was demonstrated. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

Spinning reserve quantification by a stochastic–probabilistic scheme for smart power systems with high wind penetration

International Nuclear Information System (INIS)

Khazali, Amirhossein; Kalantar, Mohsen

2015-01-01

Highlights: • A stochastic–probabilistic approach is proposed for spinning reserve quantification. • A new linearized formulation integrating reliability metrics is presented. • The framework manages the reserve provided by responsive loads and storage systems. • The proposed method is capable of detaching the spinning reserve for different uses. - Abstract: This paper introduces a novel spinning reserve quantification scheme based on a hybrid stochastic–probabilistic approach for smart power systems including high penetration of wind generation. In this research the required spinning reserve is detached into two main parts. The first part of the reserve is procured to overcome imbalances between load and generation in the system. The second part of the required spinning reserve is scheduled according to the probability of unit outages. In order to overcome uncertainties caused by wind generation and load forecasting errors different scenarios of wind generation and load uncertainties are generated. For each scenario the reserve deployed by different components are taken account as the first part of the required reserve which is used to overcome imbalances. The second part of the required reserve is based on reliability constraints. The total expected energy not supplied (TEENS) is the reliability criterion which determines the second part of the required spinning reserve to overcome unit outage possibilities. This formulation permits the independent system operator to purchase the two different types of reserve with different prices. The introduced formulation for reserve quantification is also capable of managing and detaching the reserve provided by responsive loads and energy storage devices. The problem is formulated as a mixed integer linear programming (MILP) problem including linearized formulations for reliability metrics. Obtained results show the efficiency of the proposed approach compared with the conventional stochastic and deterministic

Large-area gold nanohole arrays fabricated by one-step method for surface plasmon resonance biochemical sensing.

Science.gov (United States)

Qi, Huijie; Niu, Lihong; Zhang, Jie; Chen, Jian; Wang, Shujie; Yang, Jingjing; Guo, Siyi; Lawson, Tom; Shi, Bingyang; Song, Chunpeng

2018-04-01

Surface plasmon resonance (SPR) nanosensors based on metallic nanohole arrays have been widely reported to detect binding interactions in biological specimens. A simple and effective method for constructing nanoscale arrays is essential for the development of SPR nanosensors. In this work, we report a one-step method to fabricate nanohole arrays by thermal nanoimprinting in the matrix of IPS (Intermediate Polymer Stamp). No additional etching process or supporting substrate is required. The preparation process is simple, time-saving and compatible for roll-to-roll process, potentially allowing mass production. Moreover, the nanohole arrays were integrated into detection platform as SPR sensors to investigate different types of biological binding interactions. The results demonstrate that our one-step method can be used to efficiently fabricate large-area and uniform nanohole arrays for biochemical sensing.

Demand as frequency controlled reserve

Energy Technology Data Exchange (ETDEWEB)

Xu, Z.; Togeby, M.; OEstergaard, J.

2008-09-15

Using demand as frequency controlled reserve (DFR) is an emerging technology which allow demand to participate actively in maintaining the system operation without reducing the energy service delivered to the customer and without need of user interaction. The basic premise is that traditional frequency controlled reserves from power plants and interconnections with neighbouring systems can be costly, slow and not fulfil the need for future power grids with a high share of wind power and fewer central power plants, and an intention to perform flexible operation such as is landing. Electricity demands, on the other hand, have advantages as frequency reserve including fast activation speed, smooth linear activation, low expected costs, and well-dispersed in the distribution grid. The main challenge of DFR is new methods for monitoring the available capacity. This project has investigated the technology of using electricity demands for providing frequency reserve to power systems. Within the project the potential and economy of DFR compatible loads in Denmark has been investigated, control logic has been designed, power system impact has been investigated, potential business models has been evaluated and an implementation strategy has been suggested. The tasks and goals of the project have been successfully accomplished based on which the conclusion and future recommendation are made. This project has developed the DFR technology that enables electricity demands to autonomously disconnect or reconnect to the grid in response to system frequency variations. The developed DFR technology is proved to be a promising technology from several perspectives. Technically, using DFR is feasible to provide reserves and enhance power system frequency control, while fulfilling technical requirements such as linear activation (or reconnection) according to frequency (or time). Environmentally, the DFR technology is pollution free in contrast to traditional reserves from generation

Development of a surface plasmon resonance biosensor for real-time detection of osteogenic differentiation in live mesenchymal stem cells.

Directory of Open Access Journals (Sweden)

Yi-Chun Kuo

Full Text Available Surface plasmon resonance (SPR biosensors have been recognized as a useful tool and widely used for real-time dynamic analysis of molecular binding affinity because of its high sensitivity to the change of the refractive index of tested objects. The conventional methods in molecular biology to evaluate cell differentiation require cell lysis or fixation, which make investigation in live cells difficult. In addition, a certain amount of cells are needed in order to obtain adequate protein or messenger ribonucleic acid for various assays. To overcome this limitation, we developed a unique SPR-based biosensing apparatus for real-time detection of cell differentiation in live cells according to the differences of optical properties of the cell surface caused by specific antigen-antibody binding. In this study, we reported the application of this SPR-based system to evaluate the osteogenic differentiation of mesenchymal stem cells (MSCs. OB-cadherin expression, which is up-regulated during osteogenic differentiation, was targeted under our SPR system by conjugating antibodies against OB-cadherin on the surface of the object. A linear relationship between the duration of osteogenic induction and the difference in refractive angle shift with very high correlation coefficient was observed. To sum up, the SPR system and the protocol reported in this study can rapidly and accurately define osteogenic maturation of MSCs in a live cell and label-free manner with no need of cell breakage. This SPR biosensor will facilitate future advances in a vast array of fields in biomedical research and medical diagnosis.

48 CFR 2132.770 - Insurance premium payments and special contingency reserve.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Insurance premium payments... GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Contract Funding 2132.770 Insurance premium payments and special contingency reserve. Insurance premium payments and a special contingency reserve are made...

31 CFR 309.10 - Tenders; reservation of right to reject.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Tenders; reservation of right to... BILLS § 309.10 Tenders; reservation of right to reject. In considering the acceptance of tenders, the highest prices offered will be accepted in full down to the amount required, and if the same price appears...

15 CFR 30.41-30.44 - [Reserved

Science.gov (United States)

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false [Reserved] 30.41-30.44 Section 30.41-30.44 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE FOREIGN TRADE REGULATIONS Exemptions From the Requirements for the Filing...

77 FR 21854 - Collection of Checks and Other Items by Federal Reserve Banks and Funds Transfers Through Fedwire...

Science.gov (United States)

2012-04-12

... it is counted toward the balance maintained to satisfy a reserve balance requirement for purposes of... balance maintained to satisfy a reserve balance requirement for purposes of part 204 of this chapter... reserve balance requirement for purposes of part 204 of this chapter (Regulation D) nor make the proceeds...

The Effect of Traditional Singing Warm-Up Versus Semioccluded Vocal Tract Exercises on the Acoustic Parameters of Singing Voice.

Science.gov (United States)

Duke, Emily; Plexico, Laura W; Sandage, Mary J; Hoch, Matthew

2015-11-01

This study investigated the effect of traditional vocal warm-up versus semioccluded vocal tract exercises on the acoustic parameters of voice through three questions: does vocal warm-up condition significantly alter the singing power ratio of the singing voice? Is singing power ratio dependent upon vowel? Is perceived phonatory effort affected by warm-up condition? Hypotheses were that vocal warm-up would alter the singing power ratio, and that semioccluded vocal tract warm-up would affect the singing power ratio more than no warm-up or traditional warm-up, that singing power ratio would vary across vowel, and that perceived phonatory effort would vary with warm-up condition. This study was a within-participant repeated measures design with counterbalanced conditions. Thirteen male singers were recorded under three different conditions: no warm-up, traditional warm-up, and semioccluded vocal tract exercise warm-up. Recordings were made of these singers performing the Star Spangled Banner, and singing power ratio (SPR) was calculated from four vowels. Singers rated their perceived phonatory effort (PPE) singing the Star Spangled Banner after each warm-up condition. Warm-up condition did not significantly affect SPR. SPR was significantly different for /i/ and /e/. PPE was not significantly different between warm-up conditions. The present study did not find significant differences in SPR between warm-up conditions. SPR differences for /i/, support previous findings. PPE did not differ significantly across warm-up condition despite the expectation that traditional or semioccluded warm-up would cause a decrease. Copyright © 2015 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

Development of surface plasmon resonance imaging for detection of Acidovorax avenae subsp. citrulli (Aac) using specific monoclonal antibody.

Science.gov (United States)

Puttharugsa, Chokchai; Wangkam, Thidarat; Huangkamhang, Nongluck; Gajanandana, Oraprapai; Himananto, Orawan; Sutapun, Boonsong; Amarit, Ratthasart; Somboonkaew, Armote; Srikhirin, Toemsak

2011-01-15

An immunosensor based on surface plasmon resonance imaging (SPR imaging) using a specific monoclonal antibody 11E5 (MAb 11E5) was developed for the detection of the seed-borne bacterium Acidovorax avenae subsp. citrulli (Aac), which causes fruit blotch in watermelons and cantaloupes, and compared to the conventional ELISA technique. The 1:40 mixed self-assembled monolayer (mixed SAM) surface was used for the immobilized MAb 11E5 on sensor surface for the detection of Aac. Both whole cells and broken cells of Aac were tested by using direct and sandwich detection assay. The limit of detection (LOD) of Aac using the SPR imaging technique and a direct detection assay was 10(6)cfu/ml and a subsequent amplification of the SPR signal using a polyclonal antibody (PAb) lowered the LOD to 5×10(5) cfu/ml. The LOD for the ELISA technique was 5×10(4) cfu/ml for the detection of Aac, which was slightly better than that for the SPR technique. However, the sensor surface based on SPR imaging offered a major advantage in terms of surface regeneration, allowing at least five cycles with a shorter time assay, multi-channel analysis with an application on multiplex detection, and an ease of the surface usage for the detection of Aac in the naturally infected plant. The surface was tested against the naturally infected sample and showed good selectivity toward the Aac bacteria. Copyright © 2010 Elsevier B.V. All rights reserved.

A stochastic security approach to energy and spinning reserve scheduling considering demand response program

International Nuclear Information System (INIS)

Partovi, Farzad; Nikzad, Mehdi; Mozafari, Babak; Ranjbar, Ali Mohamad

2011-01-01

In this paper a new algorithm for allocating energy and determining the optimum amount of network active power reserve capacity and the share of generating units and demand side contribution in providing reserve capacity requirements for day-ahead market is presented. In the proposed method, the optimum amount of reserve requirement is determined based on network security set by operator. In this regard, Expected Load Not Supplied (ELNS) is used to evaluate system security in each hour. The proposed method has been implemented over the IEEE 24-bus test system and the results are compared with a deterministic security approach, which considers certain and fixed amount of reserve capacity in each hour. This comparison is done from economic and technical points of view. The promising results show the effectiveness of the proposed model which is formulated as mixed integer linear programming (MILP) and solved by GAMS software. -- Highlights: → Determination of optimal spinning reserve capacity requirement in order to satisfy desired security level set by system operator based on stochastic approach. → Scheduling energy and spinning reserve markets simultaneously. → Comparing the stochastic approach with deterministic approach to determine the advantages and disadvantages of each. → Examine the effect of demand response participation in reserve market to provide spinning reserve.

Political economy of marine reserves: Understanding the role of opportunity costs

Science.gov (United States)

Smith, Martin D.; Lynham, John; Sanchirico, James N.; Wilson, James A.

2010-01-01

The creation of marine reserves is often controversial. For decisionmakers, trying to find compromises, an understanding of the timing, magnitude, and incidence of the costs of a reserve is critical. Understanding the costs, in turn, requires consideration of not just the direct financial costs but also the opportunity costs associated with reserves. We use a discrete choice model of commercial fishermen’s behavior to examine both the short-run and long-run opportunity costs of marine reserves. Our results can help policymakers recognize the factors influencing commercial fishermen’s responses to reserve proposals. More generally, we highlight the potential drivers behind the political economy of marine reserves. PMID:20133732

Fundamental Drivers of the Cost and Price of Operating Reserves

Energy Technology Data Exchange (ETDEWEB)

Hummon, Marissa [National Renewable Energy Lab. (NREL), Golden, CO (United States); Denholm, Paul [National Renewable Energy Lab. (NREL), Golden, CO (United States); Jorgenson, Jennie [National Renewable Energy Lab. (NREL), Golden, CO (United States); Palchak, David [National Renewable Energy Lab. (NREL), Golden, CO (United States); Kirby, Brendan [Kirby Consultant; Ma, Ookie [U.S. Department of Energy, Washington, DC (United States)

2013-07-01

Operating reserves impose a cost on the electric power system by forcing system operators to keep partially loaded spinning generators available for responding to system contingencies variable demand. In many regions of the United States, thermal power plants provide a large fraction of the operating reserve requirement. Alternative sources of operating reserves, such as demand response and energy storage, may provide more efficient sources of these reserves. However, to estimate the potential value of these services, the cost of reserve services under various grid conditions must first be established. This analysis used a commercial grid simulation tool to evaluate the cost and price of several operating reserve services, including spinning contingency reserves and upward regulation reserves. These reserve products were evaluated in a utility system in the western United States, considering different system flexibilities, renewable energy penetration, and other sensitivities. The analysis demonstrates that the price of operating reserves depend highly on many assumptions regarding the operational flexibility of the generation fleet, including ramp rates and the fraction of fleet available to provide reserves.

FASB statement 121 and other accounting issues affecting reserves reporting

Energy Technology Data Exchange (ETDEWEB)

Rowden, K R [Currie Coopers and Lybrand, Toronto, ON (Canada)

1996-03-01

The provisions required by FASB 121, and their impact on oil and gas properties, were explained. This included the impact of FASB statement 121, accounting for the impairment of long-lived assets and for assets to be disposed of on oil and gas properties. A two-tiered approach to recognition and measurement was described, as well as how reserve estimates are used for measurement of impairment. Reserve reports were considered to be the basis for financial statement disclosure. Procedures for reporting of finding costs and acquisition costs according to FASB 69 were described, and the Securities and Exchange Commission (SEC) reporting requirements were summarized.

FASB statement 121 and other accounting issues affecting reserves reporting

International Nuclear Information System (INIS)

Rowden, K.R.

1996-01-01

The provisions required by FASB 121, and their impact on oil and gas properties, were explained. This included the impact of FASB statement 121, accounting for the impairment of long-lived assets and for assets to be disposed of on oil and gas properties. A two-tiered approach to recognition and measurement was described, as well as how reserve estimates are used for measurement of impairment. Reserve reports were considered to be the basis for financial statement disclosure. Procedures for reporting of finding costs and acquisition costs according to FASB 69 were described, and the Securities and Exchange Commission (SEC) reporting requirements were summarized

77 FR 69599 - Reserve Forces Policy Board (RFPB); Notice of Advisory Committee Meeting

Science.gov (United States)

2012-11-20

... force mix; the Vice Chairman of the Joint Chiefs of Staff will discuss Operational Reserve Requirements... DEPARTMENT OF DEFENSE Office of the Secretary Reserve Forces Policy Board (RFPB); Notice of Advisory Committee Meeting AGENCY: Reserve Forces Policy Board, Office of the Secretary of Defense...

Sensorless Reserved Power Control Strategy for Two-Stage Grid-Connected Photovoltaic Systems

DEFF Research Database (Denmark)

Sangwongwanich, Ariya; Yang, Yongheng; Blaabjerg, Frede

2016-01-01

Due to still increasing penetration level of grid-connected Photovoltaic (PV) systems, advanced active power control functionalities have been introduced in grid regulations. A reserved power control, where the active power from the PV panels is reserved during operation, is required for grid...... support. In this paper, a cost-effective solution to realize the reserved power control for grid-connected PV systems is proposed. The proposed solution routinely employs a Maximum Power Point Tracking (MPPT) control to estimate the available PV power and a Constant Power Generation (CPG) control...... to achieve the power reserve. In this method, the irradiance measurements that have been used in conventional control schemes to estimate the available PV power are not required, and thereby being a sensorless solution. Simulations and experimental tests have been performed on a 3-kW two-stage single...

22 CFR 226.1002 - Local cost financing. [Reserved

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Local cost financing. [Reserved] 226.1002 Section 226.1002 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF ASSISTANCE AWARDS TO U.S. NON-GOVERNMENTAL ORGANIZATIONS USAID-Specific Requirements § 226.1002 Local cost financing...

78 FR 48035 - Conservation Reserve Program, Re-Enrollment

Science.gov (United States)

2013-08-07

... longstanding USDA policy and existing handbooks. This technical amendment did not require Office of Management... Reserve Program (CRP) regulations to clarify that land with use restrictions that prohibit the production... other deed restrictions that restrict the production of agricultural commodities. A 2003 interim rule...

St. James marine terminal facility description

Energy Technology Data Exchange (ETDEWEB)

1993-10-01

The US Department of Energy (DOE) currently owns and operates a marine terminal on the west bank of the Mississippi River at St. James, Louisiana. The St. James facility was constructed by the Department to provide marine services associated with the fill and drawdown of the Strategic Petroleum Reserve (SPR) crude oil storage facilities located at Bayou Choctaw and Weeks Island, Louisiana. Although strategic to the mission of the SPR in the event of a national emergency, the St. James terminal is situated such that it has a high potential to also serve the commercial industry`s needs for crude oil terminalling and storage. The St. James terminal is located approximately 45 miles west of New Orleans and 30 miles southeast of Baton Rouge, and approximately 160 miles upstream from the mouth of the Mississippi River. Construction of the St. James terminal was initiated in 1978 and was completed in 1980. Since then, the terminal has received and transferred over 125 million barrels of crude oil to the SPR sites for storage. For crude oil distribution, the St. James terminal was connected to the neighboring LOCAP terminal by a 0.1 mile 36-inch pipeline in 1981 and to the Capline terminal by a 0.5 mile 30-inch pipeline in 1988. The terminal also has a 30-inch pipeline connection to the Koch oil terminal which was used for initial fill purposes; however, this pipeline has been disconnected and is currently inactive. A complete description of the St. James terminal facilities, operational capabilities, operational certifications, and future Government requirements are presented in Sections 2, 3, 4, and 5 respectively.

Optimal design of compact and connected nature reserves for multiple species.

Science.gov (United States)

Wang, Yicheng; Önal, Hayri

2016-04-01

When designing a conservation reserve system for multiple species, spatial attributes of the reserves must be taken into account at species level. The existing optimal reserve design literature considers either one spatial attribute or when multiple attributes are considered the analysis is restricted only to one species. We built a linear integer programing model that incorporates compactness and connectivity of the landscape reserved for multiple species. The model identifies multiple reserves that each serve a subset of target species with a specified coverage probability threshold to ensure the species' long-term survival in the reserve, and each target species is covered (protected) with another probability threshold at the reserve system level. We modeled compactness by minimizing the total distance between selected sites and central sites, and we modeled connectivity of a selected site to its designated central site by selecting at least one of its adjacent sites that has a nearer distance to the central site. We considered structural distance and functional distances that incorporated site quality between sites. We tested the model using randomly generated data on 2 species, one ground species that required structural connectivity and the other an avian species that required functional connectivity. We applied the model to 10 bird species listed as endangered by the state of Illinois (U.S.A.). Spatial coherence and selection cost of the reserves differed substantially depending on the weights assigned to these 2 criteria. The model can be used to design a reserve system for multiple species, especially species whose habitats are far apart in which case multiple disjunct but compact and connected reserves are advantageous. The model can be modified to increase or decrease the distance between reserves to reduce or promote population connectivity. © 2015 Society for Conservation Biology.

Selection bias in population-based cancer case-control studies due to incomplete sampling frame coverage.

Science.gov (United States)

Walsh, Matthew C; Trentham-Dietz, Amy; Gangnon, Ronald E; Nieto, F Javier; Newcomb, Polly A; Palta, Mari

2012-06-01

Increasing numbers of individuals are choosing to opt out of population-based sampling frames due to privacy concerns. This is especially a problem in the selection of controls for case-control studies, as the cases often arise from relatively complete population-based registries, whereas control selection requires a sampling frame. If opt out is also related to risk factors, bias can arise. We linked breast cancer cases who reported having a valid driver's license from the 2004-2008 Wisconsin women's health study (N = 2,988) with a master list of licensed drivers from the Wisconsin Department of Transportation (WDOT). This master list excludes Wisconsin drivers that requested their information not be sold by the state. Multivariate-adjusted selection probability ratios (SPR) were calculated to estimate potential bias when using this driver's license sampling frame to select controls. A total of 962 cases (32%) had opted out of the WDOT sampling frame. Cases age <40 (SPR = 0.90), income either unreported (SPR = 0.89) or greater than $50,000 (SPR = 0.94), lower parity (SPR = 0.96 per one-child decrease), and hormone use (SPR = 0.93) were significantly less likely to be covered by the WDOT sampling frame (α = 0.05 level). Our results indicate the potential for selection bias due to differential opt out between various demographic and behavioral subgroups of controls. As selection bias may differ by exposure and study base, the assessment of potential bias needs to be ongoing. SPRs can be used to predict the direction of bias when cases and controls stem from different sampling frames in population-based case-control studies.

Oak Ridge Reservation annual site environmental report summary for 1995

International Nuclear Information System (INIS)

1996-12-01

The US Department of Energy (DOE) requires an annual site environmental report from each of the sites operating under its authority. The reports present the results from the various environmental monitoring and surveillance programs carried out during the year. In addition to meeting the DOE requirement, the reports also document compliance with various state and federal laws and regulations. This report was published to fulfill those requirements for the Oak Ridge Reservation (ORR) for calendar year 1995. The report is based on thousands of environmental samples collected on and around the ORR and analyzed during the year. The data on which the report is based are published in Environmental Monitoring and Surveillance on the Oak Ridge Reservation: 1995 Data (ES/ESH-71). Both documents are highly detailed. This summary report is meant for readers who are interested in the monitoring results but who do not need to review the details

Numerical Design of Ultra-Wideband Printed Antenna for Surface Penetrating Radar Application

Directory of Open Access Journals (Sweden)

Achmad Munir

2011-08-01

Full Text Available Surface penetrating radar (SPR is an imaging device of electromagnetic wave that works by emitting and transmitting a narrow period pulse through the antenna. Due to the use of narrow period pulse, according to the Fourier transform duality, therefore ultra-wideband (UWB antenna becomes one of the most important needs in SPR system. In this paper, a novel UWB printed antenna is proposed to be used for SPR application. Basically, the proposed antenna is developed from a rectangular microstrip antenna fed by symmetric T-shaped. Some investigation methods such as resistive loading, abrupt transition, and ground plane modification are attempted to achieve required characteristics of bandwidth, radiation efficiency, and compactness needed by the system. To obtain the optimum design, the characteristics of proposed antenna are numerically investigated through the physical parameters of antenna. It is shown that proposed antenna deployed on an FR-4 Epoxy substrate with permittivity of 4.3 and thickness of 1.6mm has a compact size of 72.8mm x 60.0mm and a large bandwidth of 50MHz-5GHz which is suitable for SPR application.

The US Strategic Posture Review: Issues for the New Administration

National Research Council Canada - National Science Library

Bunn, M

2001-01-01

.... The forthcoming Strategic Posture Review (SPR) needs to fundamentally reassess the purposes of nuclear weapons, missile defenses, and the requirements of deterrence and stability in the new security environment...

Recent advances in surface plasmon resonance imaging: detection speed, sensitivity, and portability

Directory of Open Access Journals (Sweden)

Zeng Youjun

2017-06-01

Full Text Available Surface plasmon resonance (SPR biosensor is a powerful tool for studying the kinetics of biomolecular interactions because they offer unique real-time and label-free measurement capabilities with high detection sensitivity. In the past two decades, SPR technology has been successfully commercialized and its performance has continuously been improved with lots of engineering efforts. In this review, we describe the recent advances in SPR technologies. The developments of SPR technologies focusing on detection speed, sensitivity, and portability are discussed in details. The incorporation of imaging techniques into SPR sensing is emphasized. In addition, our SPR imaging biosensors based on the scanning of wavelength by a solid-state tunable wavelength filter are highlighted. Finally, significant advances of the vast developments in nanotechnology-associated SPR sensing for sensitivity enhancements are also reviewed. It is hoped that this review will provide some insights for researchers who are interested in SPR sensing, and help them develop SPR sensors with better sensitivity and higher throughput.

Recent advances in surface plasmon resonance imaging: detection speed, sensitivity, and portability

Science.gov (United States)

Zeng, Youjun; Hu, Rui; Wang, Lei; Gu, Dayong; He, Jianan; Wu, Shu-Yuen; Ho, Ho-Pui; Li, Xuejin; Qu, Junle; Gao, Bruce Zhi; Shao, Yonghong

2017-06-01

Surface plasmon resonance (SPR) biosensor is a powerful tool for studying the kinetics of biomolecular interactions because they offer unique real-time and label-free measurement capabilities with high detection sensitivity. In the past two decades, SPR technology has been successfully commercialized and its performance has continuously been improved with lots of engineering efforts. In this review, we describe the recent advances in SPR technologies. The developments of SPR technologies focusing on detection speed, sensitivity, and portability are discussed in details. The incorporation of imaging techniques into SPR sensing is emphasized. In addition, our SPR imaging biosensors based on the scanning of wavelength by a solid-state tunable wavelength filter are highlighted. Finally, significant advances of the vast developments in nanotechnology-associated SPR sensing for sensitivity enhancements are also reviewed. It is hoped that this review will provide some insights for researchers who are interested in SPR sensing, and help them develop SPR sensors with better sensitivity and higher throughput.

Navy Reserve: Not Ready for OLC

Science.gov (United States)

2010-06-11

Navy. Additionally, the need for qualified personnel inspired the Navy to create a new reserve program, the Women Accepted for Volunteer Emergency...Service (WAVES), which peaked at 86,000 women serving in stateside assignments. The Korean War required the mobilization of over 182,000 Navy...Office of Naval Intelligence 3348 3427 1590 47.49 24.50 ONR - NRL 211 231 0 0.00 0.00 Selective Service 42 29 0 0.00 0.00 Space & Warfare Systems Command

Industry wins, loses in House bill

International Nuclear Information System (INIS)

Anon.

1992-01-01

This paper reports that the House of Representatives has approved a plan to limit U.S. gas prorationing by the states but rejected a move to require petroleum refiners and importers to place 1% of their oil or products volumes into the Strategic Petroleum Reserve. The oil industry lobbied heavily against the SPR provision, which went down 263-135. The House then passed its omnibus energy bill 381-37. It is designed to facilitate all types of energy production while promoting conservation. The legislation also imposes bans on offshore leasing but gives independent producers limited relief from the alternative minimum tax (AMT) and does not include a mandate for use of ethanol in gasoline

Nanoplasmonic biochips for rapid label-free detection of imidacloprid pesticides with a smartphone.

Science.gov (United States)

Lee, Kuang-Li; You, Meng-Lin; Tsai, Chia-Hsin; Lin, En-Hung; Hsieh, Shu-Yi; Ho, Ming-Hsun; Hsu, Ju-Chun; Wei, Pei-Kuen

2016-01-15

The widespread and intensive use of neonicotinoid insecticides induces negative cascading effects on ecosystems. It is desirable to develop a portable sensitive sensing platform for on-site screening of high-risk pesticides. We combined an indirect competitive immunoassay, highly sensitive surface plasmon resonance (SPR) biochip and a simple portable imaging setup for label-free detection of imidacloprid pesticides. The SPR biochip consists of several capped nanoslit arrays with different periods which form a spectral image on the chip. The qualitative and semiquantitative analyses of pesticides can be directly observed from the spot shift on the chip. The precise semiquantitative analyses can be further completed by using image processing in a smartphone. We demonstrate simultaneous detection of four different concentrations of imidacloprid pesticides. The visual detection limit is about 1ppb, which is well below the maximum residue concentration permitted by law (20ppb). Compared to the one-step strip assay, the proposed chip is capable of performing semiquantitative analyses and multiple detection. Compared to the enzyme-linked immunosorbent assay, our method is label-free and requires simple washing steps and short reaction time. In addition, the label-free chip has a comparable sensitivity but wider working range than those labeling techniques. Copyright © 2015 Elsevier B.V. All rights reserved.

The Economics of NASA Mission Cost Reserves

Science.gov (United States)

Whitley, Sally; Shinn, Stephen

2012-01-01

Increases in NASA mission costs are well-noted but not well-understood, and there is little evidence that they are decreasing in frequency or amount over time. The need to control spending has led to analysis of the causes and magnitude of historical mission overruns, and many program control efforts are being implemented to attempt to prevent or mitigate the problem (NPR 7120). However, cost overruns have not abated, and while some direct causes of increased spending may be obvious (requirements creep, launch delays, directed changes, etc.), the underlying impetus to spend past the original budget may be more subtle. Gaining better insight into the causes of cost overruns will help NASA and its contracting organizations to avoid .them. This paper hypothesizes that one cause of NASA mission cost overruns is that the availability of reserves gives project team members an incentive to make decisions and behave in ways that increase costs. We theorize that the presence of reserves is a contributing factor to cost overruns because it causes organizations to use their funds less efficiently or to control spending less effectively. We draw a comparison to the insurance industry concept of moral hazard, the phenomenon that the presence of insurance causes insureds to have more frequent and higher insurance losses, and we attempt to apply actuarial techniques to quantifY the increase in the expected cost of a mission due to the availability of reserves. We create a theoretical model of reserve spending motivation by defining a variable ReserveSpending as a function of total reserves. This function has a positive slope; for every dollar of reserves available, there is a positive probability of spending it. Finally, the function should be concave down; the probability of spending each incremental dollar of reserves decreases progressively. We test the model against available NASA CADRe data by examining missions with reserve dollars initially available and testing whether

Surface plasmon resonance based biosensor: A new platform for rapid diagnosis of livestock diseases

Directory of Open Access Journals (Sweden)

Pravas Ranjan Sahoo

2016-12-01

Full Text Available Surface plasmon resonance (SPR based biosensors are the most advanced and developed optical label-free biosensor technique used for powerful detection with vast applications in environmental protection, biotechnology, medical diagnostics, drug screening, food safety, and security as well in livestock sector. The livestock sector which contributes the largest economy of India, harbors many bacterial, viral, and fungal diseases impacting a great loss to the production and productive potential which is a major concern in both small and large ruminants. Hence, an accurate, sensitive, and rapid diagnosis is required for prevention of these above-mentioned diseases. SPR based biosensor assay may fulfill the above characteristics which lead to a greater platform for rapid diagnosis of different livestock diseases. Hence, this review may give a detail idea about the principle, recent development of SPR based biosensor techniques and its application in livestock sector.

SU-E-J-136: Investigation Into Robustness of Stopping Power Calculated by DECT and SECT for Proton Therapy Treatment Planning

Energy Technology Data Exchange (ETDEWEB)

Zhu, J [University of Adelaide, Adelaide, SA (Australia); Penfold, S [University of Adelaide, Adelaide, SA (Australia); Royal Adelaide Hospital, Adelaide, SA (Australia)

2015-06-15

Purpose: To investigate the robustness of dual energy CT (DECT) and single energy CT (SECT) proton stopping power calibration techniques and quantify the associated errors when imaging a phantom differing in chemical composition to that used during stopping power calibration. Methods: The CIRS tissue substitute phantom was scanned in a CT-simulator at 90kV and 140kV. This image set was used to generate a DECT proton SPR calibration based on a relationship between effective atomic number and mean excitation energy. A SECT proton SPR calibration based only on Hounsfield units (HUs) was also generated. DECT and SECT scans of a second phantom of known density and chemical composition were performed. The SPR of the second phantom was calculated with the DECT approach (SPR-DECT),the SECT approach (SPR-SECT) and finally the known density and chemical composition of the phantom (SPR-ref). The DECT and SECT image sets were imported into the Pinnacle{sup 3} research release of proton therapy treatment planning. The difference in dose when exposed to a common pencil beam distribution was investigated. Results: SPR-DECT was found to be in better agreement with SPR-ref than SPR- SECT. The mean difference in SPR for all materials was 0.51% for DECT and 6.89% for SECT. With the exception of Teflon, SPR-DECT was found to agree with SPR-ref to within 1%. Significant differences in calculated dose were found when using the DECT image set or the SECT image set. Conclusion: The DECT calibration technique was found to be more robust to situations in which the physical properties of the test materials differed from the materials used during SPR calibration. Furthermore, it was demonstrated that the DECT and SECT SPR calibration techniques can Result in significantly different calculated dose distributions.

Classification of uranium reserves/resources

International Nuclear Information System (INIS)

1998-08-01

Projections of future availability of uranium to meet present and future nuclear power requirements depend on the reliability of uranium resource estimates. Lack of harmony of the definition of the different classes of uranium reserves and resources between countries makes the compilation and analysis of such information difficult. The problem was accentuated in the early 1990s with the entry of uranium producing countries from the former Soviet Union, eastern Europe and China into the world uranium supply market. The need for an internationally acceptable reserve/resource classification system and terminology using market based criteria is therefore obvious. This publication was compiled from participant's contributions and findings of the Consultants Meetings on Harmonization of Uranium Resource Assessment Concepts held in Vienna from 22 to 25 June 1992, and two Consultants Meetings on the Development of a More Meaningful Classification of Uranium Resources held in Kiev, Ukraine on 24-26 April 1995 and 20-23 August 1996. This document includes 11 contributions, summary, list of participants of the Consultants Meetings. Each contribution has been indexed and provided with an abstract

US crude oil, natural gas, and natural gas liquids reserves: 1990 annual report

International Nuclear Information System (INIS)

1991-09-01

The primary focus of this report is to provide an accurate estimate of US proved reserves of crude oil, natural gas, and natural gas liquids. These estimates were considered essential to the development, implementation, and evaluation of natural energy policy and legislation. In the past, the government and the public relied upon industry estimates of proved reserves. These estimates were prepared jointly by the American Petroleum Institute (API) and the American Gas Association (AGA) and published in their annual report, Reserves of Crude Oil, Natural Gas Liquids, and Natural Gas in the United States and Canada. However, API and AGA ceased publication of reserves estimates after their 1979 report. By the mid-1970's, various federal agencies had separately established programs to collect data on, verify, or independently estimate domestic proved reserves of crude oil or natural gas. Each program was narrowly defined to meet the particular needs of the sponsoring agency. In response to recognized need for unified, comprehensive proved reserves estimates, Congress in 1977 required the Department of Energy to prepare such estimates. To meet this requirement, the EIA's reserves program was undertaken to establish a unified, verifiable, comprehensive, and continuing statistical series for proved reserves of crude oil and natural gas. The program was expanded to include proved reserves of natural gas liquids in the 1979 report. 36 refs., 11 figs., 16 tabs

A surface plasmon resonance immunosensor for detecting a dioxin precursor using a gold binding polypeptide

DEFF Research Database (Denmark)

Soh, N; Tokuda, T.; Watanabe, T.

2003-01-01

A surface plasmon resonance (SPR) based biosensor was developed for monitoring 2,4-dichlorophenol, a known dioxin precursor, using an indirect competitive immunoassay. The SPR sensor was fabricated by immobilizing a gold-thin layer on the surface of an SPR sensor chip with an anti-(2,4-dichloroph......A surface plasmon resonance (SPR) based biosensor was developed for monitoring 2,4-dichlorophenol, a known dioxin precursor, using an indirect competitive immunoassay. The SPR sensor was fabricated by immobilizing a gold-thin layer on the surface of an SPR sensor chip with an anti-(2...

Individual Ready Reserve: It's Relevance in Supporting the Long War

National Research Council Canada - National Science Library

Chisholm, Shelley A

2008-01-01

... in sustaining personnel readiness while supporting on going operations. In response to meeting these personnel readiness concerns, the Army Reserve will require the call-up of Soldiers currently serving in the IRR...

Airpower and the Reserve Components (Joint Force Quarterly, Issue 36)

National Research Council Canada - National Science Library

Meilinger, Phillip S

2004-01-01

.... All ARC units and personnel must meet active component standards. This simple but immutable requirement means both the Guard and Reserve are combat-ready and available to deploy worldwide within 72 hours...

Status of fossil fuel reserves; Etat des reserves des combustibles fossiles

Energy Technology Data Exchange (ETDEWEB)

Laherrere, J

2005-07-01

Reserves represent the sum of past and future productions up to the end of production. In most countries the reserve data of fields are confidential. Therefore, fossil fuel reserves are badly known because the published data are more political than technical and many countries make a confusion between resources and reserves. The cumulated production of fossil fuels represents only between a third and a fifth of the ultimate reserves. The production peak will take place between 2020 and 2050. In the ultimate reserves, which extrapolate the past, the fossil fuels represent three thirds of the overall energy. This document analyses the uncertainties linked with fossil fuel reserves: reliability of published data, modeling of future production, comparison with other energy sources, energy consumption forecasts, reserves/production ratio, exploitation of non-conventional hydrocarbons (tar sands, extra-heavy oils, bituminous shales, coal gas, gas shales, methane in overpressure aquifers, methane hydrates), technology impacts, prices impact, and reserves growth. (J.S.)

VAr reserve concept applied to a wind power plant

DEFF Research Database (Denmark)

Martinez, Jorge; Kjær, Philip C.; Rodriguez, Pedro

2011-01-01

to wind power plants. This paper proposes two different VAr reserve control strategies for a wind power plant. The amount of dynamic VAr available most of the operation time, makes the wind power plant (WPP) a good candidate to include a VAr reserve management system. Two different ways of implementing...... a VAr management system are proposed and analyzed. Such a reactive power reserve may be provided by the wind power plant since the amount of reactive power installed for most active power working points exceeds the demand required by the grid operator. Basically, this overrated reactive power capacity...... is a consequence of sizing wind turbine facilities for maximum active power level. The reactive power losses, due to active power transportation inside the plant (normally two transformers), and P-Q wind turbine characteristics define the P-Q reserve chart. By utilizing the intrinsic overrated reactive power...

An optical sensing approach for the noninvasive transdermal monitoring of cortisol

Science.gov (United States)

Hwang, Yongsoon; Gupta, Niraj K.; Ojha, Yagya R.; Cameron, Brent D.

2016-03-01

Cortisol, a biomarker of stress, has recently been shown to have potential in evaluating the physiological state of individuals diagnosed with stress-related conditions including chronic fatigue syndrome. Noninvasive techniques to extract biomarkers from the body are a topic of considerable interest. One such technique to achieve this is known as reverse iontophoresis (RI) which is capable of extracting biomolecules through the skin. Unfortunately, however, the extracted levels are often considerably lower in concentration than those found in blood, thereby requiring a very sensitive analytical method with a low limit of detection. A promising sensing approach, which is well suited to handle such samples, is Surface Plasmon Resonance (SPR) spectroscopy. When coupled with aptamer modified surfaces, such sensors can achieve both selectivity and the required sensitivity. In this study, fabrication and characterization of a RIbased SPR biosensor for the measurement of cortisol has been developed. The optical mount and diffusion cell were both fabricated through the use of 3D printing techniques. The SPR sensor was configured to employ a prism couplerbased arrangement with a laser generation module and CCD line sensor. Cortisol-specific DNA aptamers were immobilized onto a gold surface to achieve the necessary selectivity. For demonstration purposes, cortisol was extracted by the RI system using a skin phantom flow system capable of generating time dependent concentration profiles. The captured sample was then transported using a micro-fluidic platform from the RI collection site to the SPR sensor for real-time monitoring. Analysis and system control was accomplished within a developed LabVIEW® program.

Foreign Exchange Reserves and the Reserve Bank’s Balance Sheet

OpenAIRE

Christian Vallence

2012-01-01

The Reserve Bank of Australia holds and manages the nation’s foreign exchange reserve assets in order to meet its policy objectives. While Australia’s foreign exchange reserves are relatively modest by international standards, they nonetheless constitute a sizeable portion of the Bank’s balance sheet, and variations in the Australian dollar value of these reserves are usually the most volatile component of the Bank’s profit and loss statement. This article discusses some of the key decisions ...

SCPR: Secure Crowdsourcing-Based Parking Reservation System

Directory of Open Access Journals (Sweden)

Changsheng Wan

2017-01-01

Full Text Available The crowdsourcing-based parking reservation system is a new computing paradigm, where private owners can rent their parking spots out. Security is the main concern for parking reservation systems. However, current schemes cannot provide user privacy protection for drivers and have no key agreement functions, resulting in a lot of security problems. Moreover, current schemes are typically based on the time-consuming bilinear pairing and not suitable for real-time applications. To solve these security and efficiency problems, we present a novel security protocol with user privacy called SCPR. Similar to protocols of this field, SCPR can authenticate drivers involved in the parking reservation system. However, different from other well-known approaches, SCPR uses pseudonyms instead of real identities for providing user privacy protection for drivers and designs a novel pseudonym-based key agreement protocol. Finally, to reduce the time cost, SCPR designs several novel cryptographic algorithms based on the algebraic signature technique. By doing so, SCPR can satisfy a number of security requirements and enjoy high efficiency. Experimental results show SCPR is feasible for real world applications.

45 CFR 146.120 - Interaction with the Family and Medical Leave Act. [Reserved

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Interaction with the Family and Medical Leave Act. [Reserved] 146.120 Section 146.120 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS... Interaction with the Family and Medical Leave Act. [Reserved] ...

Design of Helical Self-Piercing Rivet for Joining Aluminum Alloy and High-Strength Steel Sheets

International Nuclear Information System (INIS)

Kim, W. Y.; Kim, D. B.; Park, J. G; Kim, D. H.; Kim, K. H.; Lee, I. H.; Cho, H. Y.

2014-01-01

A self-piercing rivet (SPR) is a mechanical component for joining dissimilar material sheets such as those of aluminum alloy and steel. Unlike conventional rivets, the SPR directly pierces sheets without the need for drilling them beforehand. However, the regular SPR can undergo buckling when it pierces a high-strength steel sheet, warranting the design of a helical SPR. In this study, the joining and forging processes using the helical SPR were simulated using the commercial FEM code, DEFORM-3D. High-tensile-strength steel sheets of different strengths were joined with aluminum alloy sheets using the designed helical SPR. The simulation results were found to agree with the experimental results, validating the optimal design of a helical SPR that can pierce high-strength steel sheets

Design of Helical Self-Piercing Rivet for Joining Aluminum Alloy and High-Strength Steel Sheets

Energy Technology Data Exchange (ETDEWEB)

Kim, W. Y.; Kim, D. B.; Park, J. G; Kim, D. H.; Kim, K. H.; Lee, I. H.; Cho, H. Y. [Chungbuk National University, Cheongju (Korea, Republic of)

2014-07-15

A self-piercing rivet (SPR) is a mechanical component for joining dissimilar material sheets such as those of aluminum alloy and steel. Unlike conventional rivets, the SPR directly pierces sheets without the need for drilling them beforehand. However, the regular SPR can undergo buckling when it pierces a high-strength steel sheet, warranting the design of a helical SPR. In this study, the joining and forging processes using the helical SPR were simulated using the commercial FEM code, DEFORM-3D. High-tensile-strength steel sheets of different strengths were joined with aluminum alloy sheets using the designed helical SPR. The simulation results were found to agree with the experimental results, validating the optimal design of a helical SPR that can pierce high-strength steel sheets.

A surface plasmon resonance-based immunosensors for sensitive detection of heroin

International Nuclear Information System (INIS)

Wu Zhongcheng; Wang Lianchao; Ge Yu; Yu Chengduan; Fang Tingjian; Chen Wenge

2000-01-01

A simple technique for sensitive detection of heroine based on surface-plasmon resonance has been theoretically and experimentally investigated. The experiment was realized by using an anti-MO monoclonal antibody and a morphine (MO)-bovine serum albumin (MO-BSA) conjugate (antigen). The reason for using MO-BSA in the detection of heroine was also discussed. MO-BSA was immobilized on a gold thin film of SPR sensor chip by physical adsorption. The configuration of the device is allowed to be further miniaturized, which is required for the construction of a portable SPR device in the application of in-situ analysis

Naval Reserve Annual Operating Costs

Science.gov (United States)

1975-10-29

C. c ) CPi i 0 0 00 0 le C C.C~r In 1]1 In 00 It .- I to C-38 ’U2 WIX ’W~ - m u. -C-LC m4 C v , v ul FA ?w % -D 1 o r cl jc j, II t %c oK W)i Ir of... platform programs, while Program 11 contains 26 sub-programs each having a separate Reserve program sponsor. The distribution of Program 11 resources is...a mix of specific skills required to bring an active Navy oper-Iating platform to organizational manning. Each SRU is tailored to a specific ship

Mass effect of redox reactions: A novel mode for surface plasmon resonance-based bioanalysis.

Science.gov (United States)

Yuan, Pei-Xin; Deng, Sheng-Yuan; Xin, Peng; Ji, Xu-Bo; Shan, Dan; Cosnier, Serge

2015-12-15

The pursuit of more specific and sensitive response is a perpetual goal for modern bioassays. This work proposed a novel label-free strategy about redox-related mass effect based on the surface plasmon resonance (SPR) technique for ultrasensitive determination of DNA. The protocol starts with the modification of SPR gilded disk with the capture DNA (cDNA). After the conjugation of immobilized cDNA with the target DNA (tDNA), the hybridization chain reaction was triggered by the introduction of mutual partial complementary primers to elongate the terminal into a nanoscale duplex. As it is reported that porphyrin could intercalate into the grooves of the double-stranded DNA (dsDNA) scaffold, multiple positive-charged Fe(III)meso-tetra(N-methyl-4-pyridyl) porphine (FeTMPyP) with symmetric structure were uptaken for in situ formation of porphyrin-dsDNA complex. Given FeTMPyP a highly efficient catalysis for the peroxide reduction, its presence as a biomimetic cofactor was validated via circular dichroism and UV-vis spectroscopy, demonstrating a tight binding as well as high catalytic activity and stability. Using 4-chloro-1-naphthol as a proton donor, the catalytic reduction of H2O2 would oxidize it into insoluble benzo-4-chloro-hexadienone, which simultaneously deposited on the heterogeneous interface, leading to a significant amplification in both SPR response and topological height profile. The signal increment was proportional to the concentration of tDNA, thus an ultrasensitive SPR-based DNA assay was developed with a linear range over four orders of magnitudes and a sub-femtomolar detection limit of 0.73 fM. The developed methodology exemplifies a different way of thinking about mass-sensing modes, extending conventional SPR-based DNA analysis to relevant biomedical applications. Copyright © 2015 Elsevier B.V. All rights reserved.

Surface Plasmon Resonance kinetic analysis of the interaction between G-quadruplex nucleic acids and an anti-G-quadruplex monoclonal antibody.

Science.gov (United States)

Lago, Sara; Nadai, Matteo; Rossetto, Monica; Richter, Sara N

2018-06-01

G-quadruplexes (G4s) are nucleic acids secondary structures formed in guanine-rich sequences. Anti-G4 antibodies represent a tool for the direct investigation of G4s in cells. Surface Plasmon Resonance (SPR) is a highly sensitive technology, suitable for assessing the affinity between biomolecules. We here aimed at improving the orientation of an anti-G4 antibody on the SPR sensor chip to optimize detection of binding antigens. SPR was employed to characterize the anti-G4 antibody interaction with G4 and non-G4 oligonucleotides. Dextran-functionalized sensor chips were used both in covalent coupling and capturing procedures. The use of two leading molecule for orienting the antibody of interest allowed to improve its activity from completely non-functional to 65% active. The specificity of the anti-G4 antobody for G4 structures could thus be assessed with high sensitivity and reliability. Optimization of the immobilization protocol for SPR biosensing, allowed us to determine the anti-G4 antibody affinity and specificity for G4 antigens with higher sensitivity with respect to other in vitro assays such as ELISA. Anti-G4 antibody specificity is a fundamental assumption for the future utilization of this kind of antibodies for monitoring G4s directly in cells. The heterogeneous orientation of amine-coupling immobilized ligands is a general problem that often leads to partial or complete inactivation of the molecules. Here we describe a new strategy for improving ligand orientation: driving it from two sides. This principle can be virtually applied to every molecule that loses its activity or is poorly immobilized after standard coupling to the SPR chip surface. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

A retirement and a reservation: a retrospective autobiography.

Science.gov (United States)

Lee, Sok K

2012-01-01

A retirement is a rite of passage that requires careful planning, because it forces a retiree to make a shift in the paradigm in life. For 37 years, I was a healing professional, a breadwinner, and a working spouse. I am now a jobless loner, an inactive pensioner, and a homebound spouse. In this retrospective autobiography, I suggest a few points to help my younger colleagues to better their upcoming retirement: professional, financial, social, and familial. To overcome Erikson's identity crisis, I volunteered to be a wounded healer at Warm Springs Indian Reservation. My volunteer medical service at Warm Springs Indian Reservation was a good antidote to creatively overcome my postretirement blues.

SPR/MS

DEFF Research Database (Denmark)

Borch, Jonas; Roepstorff, Peter

2010-01-01

Surface plasmon resonance is widely used to study binding interactions with proteins, potentially yielding information on kinetics, thermodynamics and active concentrations. However, the technology cannot identify the involved interaction partners. Mass spectrometry, on the other hand, can be use...

Liquidity implications of a commitment period reserve at national and global levels

International Nuclear Information System (INIS)

Haites, Erik; Missfeldt, Fanny

2004-01-01

The Kyoto Protocol, if it enters into force, will establish international emissions trading for quota that can be used for compliance with Protocol commitments. Concern that the non-compliance regime might not be sufficient to deter overselling led to adoption of the commitment period reserve requirement. This paper analyses the commitment period reserve in terms of (a) the liquidity of the international emissions trading market, and (b) international liquidity for domestic emissions trading programs in Annex B countries. The liquidity of the international greenhouse gas emissions trading market is measured as the sum of the quota surplus to the reserve requirement of net seller countries divided by the average annual assigned amount of all Annex B Parties and by the BAU emissions of Annex B Parties. Both measures are calculated using both the average values across 500 projections of future emissions and the values that yield the lowest liquidity (lowest reserves, highest emissions). Even the lowest estimates indicate liquidity comparable to that of the existing emissions trading programs. In addition, the international liquidity for domestic emissions trading programs with the commitment period reserve is likely to be comparable to or better than that of existing emissions trading markets, even under conservative assumptions

Fatigue Life Prediction of Self-Piercing Rivet Joints Between Magnesium and Aluminum Alloys

Directory of Open Access Journals (Sweden)

Kang Hong-Tae

2018-01-01

Full Text Available Various light materials including aluminum alloys and magnesium alloys are being used to reduce the weight of vehicle structures. Joining of dissimilar materials is always a challenging task to construct a solid structure. Self-piercing rivet (SPR joint is one of various joining methods for dissimilar materials. Front shock tower structures were constructed with magnesium alloy (AM60 joined to aluminum alloy (Al6082 by SPR joints. To evaluate the durability performance of the SPR joints in the structures, fatigue tests of the front shock tower structures were conducted with constant amplitude loadings. Furthermore, this study investigated fatigue life prediction method of SPR joints and compared the fatigue life prediction results with that of experimental results. For fatigue life prediction of the SPR joints in the front shock tower structures, lap-shear and cross-tension specimens of SPR joint were constructed and tested to characterize the fatigue properties of the SPR joint. Then, the SPR joint was represented with area contact method (ACM in finite element (FE models. The load-life curves of the lap-shear and cross-tension specimens were converted to a structural stress-life (S-N curve of the SPR joints. The S-N curve was used to predict fatigue life of SPR joints in the front shock tower structures. The test results and the prediction results were well correlated.

Pricing the Ramping Reserve and Capacity Reserve in Real Time Markets

OpenAIRE

Ye, Hongxing; Li, Zuyi

2015-01-01

The increasing penetration of renewable energy in recent years has led to more uncertainties in power systems. In order to maintain system reliability and security, electricity market operators need to keep certain reserves in the Security-Constrained Economic Dispatch (SCED) problems. A new concept, deliverable generation ramping reserve, is proposed in this paper. The prices of generation ramping reserves and generation capacity reserves are derived in the Affine Adjustable Robust Optimizat...

An Ontological-Fuzzy Approach to Advance Reservation in Multi-Cluster Grids

International Nuclear Information System (INIS)

Ferreira, D J; Dantas, M A R; Bauer, Michael A

2010-01-01

Advance reservation is an important mechanism for a successful utilization of available resources in distributed multi-cluster environments. This mechanism allows, for example, a user to provide parameters aiming to satisfy requirements related to applications' execution time and temporal dependence. This predictability can lead the system to reach higher levels of QoS. However, the support for advance reservation has been restricted due to the complexity of large scale configurations and also dynamic changes verified in these systems. In this research work it is proposed an advance reservation method, based on a ontology-fuzzy approach. It allows a user to reserve a wide variety of resources and enable large jobs to be reserved among different nodes. In addition, it dynamically verifies the possibility of reservation with the local RMS, avoiding future allocation conflicts. Experimental results of the proposal, through simulation, indicate that the proposed mechanism reached a successful level of flexibility for large jobs and more appropriated distribution of resources in a distributed multi-cluster configuration.

An Ontological-Fuzzy Approach to Advance Reservation in Multi-Cluster Grids

Energy Technology Data Exchange (ETDEWEB)

Ferreira, D J; Dantas, M A R; Bauer, Michael A, E-mail: ded@inf.ufsc.br, E-mail: mario@inf.ufsc.br, E-mail: bauer@csd.uwo.ca

2010-11-01

Advance reservation is an important mechanism for a successful utilization of available resources in distributed multi-cluster environments. This mechanism allows, for example, a user to provide parameters aiming to satisfy requirements related to applications' execution time and temporal dependence. This predictability can lead the system to reach higher levels of QoS. However, the support for advance reservation has been restricted due to the complexity of large scale configurations and also dynamic changes verified in these systems. In this research work it is proposed an advance reservation method, based on a ontology-fuzzy approach. It allows a user to reserve a wide variety of resources and enable large jobs to be reserved among different nodes. In addition, it dynamically verifies the possibility of reservation with the local RMS, avoiding future allocation conflicts. Experimental results of the proposal, through simulation, indicate that the proposed mechanism reached a successful level of flexibility for large jobs and more appropriated distribution of resources in a distributed multi-cluster configuration.

Reform of reserve requirements for nuclear decommissioning, dismantling and disposal; Reform der Atomrueckstellungen fuer Stilllegung/Rueckbau und Entsorgung

Energy Technology Data Exchange (ETDEWEB)

Meyer, Bettina [Forum Oekologisch-Soziale Marktwirtschaft e.V. (FOeS), Berlin (Germany); Kuechler, Swantje; Wronski, Rupert [Forum Oekologisch-Soziale Marktwirtschaft e.V. (FOeS), Berlin (Germany). Bereich Energiepolitik

2015-07-15

This article reports on the ongoing intense discussion as to whether the financial reserves of nuclear power plant operators are sufficient. It starts out with an overview of the current scientific and political debate. This is followed by a brief analysis of nuclear financial reserves in 2014 and preceding years. The authors then present the reform concept of the Forum Oekologisch-Soziale Marktwirtschaft (FOes) and go on to compare it with concepts from the political realm.

Ultrasensitive and selective gold film-based detection of mercury (II) in tap water using a laser scanning confocal imaging-surface plasmon resonance system in real time.

Science.gov (United States)

Zhang, Hongyan; Yang, Liquan; Zhou, Bingjiang; Liu, Weimin; Ge, Jiechao; Wu, Jiasheng; Wang, Ying; Wang, Pengfei

2013-09-15

An ultrasensitive and selective detection of mercury (II) was investigated using a laser scanning confocal imaging-surface plasmon resonance system (LSCI-SPR). The detection limit was as low as 0.01ng/ml for Hg(2+) ions in ultrapure and tap water based on a T-rich, single-stranded DNA (ssDNA)-modified gold film, which can be individually manipulated using specific T-Hg(2+)-T complex formation. The quenching intensity of the fluorescence images for rhodamine-labeled ssDNA fitted well with the changes in SPR. The changes varied with the Hg(2+) ion concentration, which is unaffected by the presence of other metal ions. The coefficients obtained for ultrapure and tap water were 0.99902 and 0.99512, respectively, for the linear part over a range of 0.01-100ng/ml. The results show that the double-effect sensor has potential for practical applications with ultra sensitivity and selectivity, especially in online or real-time monitoring of Hg(2+) ions pollution in tap water with the further improvement of portable LSCI-SPR instrument. Copyright © 2013 Elsevier B.V. All rights reserved.

Characterization of lipid films by an angle-interrogation surface plasmon resonance imaging device.

Science.gov (United States)

Liu, Linlin; Wang, Qiong; Yang, Zhong; Wang, Wangang; Hu, Ning; Luo, Hongyan; Liao, Yanjian; Zheng, Xiaolin; Yang, Jun

2015-04-01

Surface topographies of lipid films have an important significance in the analysis of the preparation of giant unilamellar vesicles (GUVs). In order to achieve accurately high-throughput and rapidly analysis of surface topographies of lipid films, a homemade SPR imaging device is constructed based on the classical Kretschmann configuration and an angle interrogation manner. A mathematical model is developed to accurately describe the shift including the light path in different conditions and the change of the illumination point on the CCD camera, and thus a SPR curve for each sampling point can also be achieved, based on this calculation method. The experiment results show that the topographies of lipid films formed in distinct experimental conditions can be accurately characterized, and the measuring resolution of the thickness lipid film may reach 0.05 nm. Compared with existing SPRi devices, which realize detection by monitoring the change of the reflective-light intensity, this new SPRi system can achieve the change of the resonance angle on the entire sensing surface. Thus, it has higher detection accuracy as the traditional angle-interrogation SPR sensor, with much wider detectable range of refractive index. Copyright © 2015 Elsevier B.V. All rights reserved.

Simplified derivation of stopping power ratio in the human body from dual-energy CT data.

Science.gov (United States)

Saito, Masatoshi; Sagara, Shota

2017-08-01

The main objective of this study is to propose an alternative parameterization for the empirical relation between mean excitation energies (I-value) and effective atomic numbers (Z eff ) of human tissues, and to present a simplified formulation (which we called DEEDZ-SPR) for deriving the stopping power ratio (SPR) from dual-energy (DE) CT data via electron density (ρ e ) and Z eff calibration. We performed a numerical analysis of this DEEDZ-SPR method for the human-body-equivalent tissues of ICRU Report 46, as objects of interest with unknown SPR and ρ e . The attenuation coefficients of these materials were calculated using the XCOM photon cross-sections database. We also applied the DEEDZ-SPR conversion to experimental DECT data available in the literature, which was measured for the tissue-characterization phantom using a dual-source CT scanner at 80 kV and 140 kV/Sn. It was found that the DEEDZ-SPR conversion enables the calculation of SPR simply by means of the weighted subtraction of an electron-density image and a low- or high-kV CT image. The simulated SPRs were in excellent agreement with the reference values over the SPR range from 0.258 (lung) to 3.638 (bone mineral-hydroxyapatite). The relative deviations from the reference SPR were within ±0.6% for all ICRU-46 human tissues, except for the thyroid that presented a -1.1% deviation. The overall root-mean-square error was 0.21%. Application to experimental DECT data confirmed this agreement within the experimental accuracy, which demonstrates the practical feasibility of the method. The DEEDZ-SPR conversion method could facilitate the construction of SPR images as accurately as a recent DECT-based calibration procedure of SPR parameterization based directly on the CT numbers in a DECT data set. © 2017 American Association of Physicists in Medicine.

Reserve Growth in Oil Fields of West Siberian Basin, Russia

Science.gov (United States)

Verma, Mahendra K.; Ulmishek, Gregory F.

2006-01-01

Although reserve (or field) growth has proven to be an important factor contributing to new reserves in mature petroleum basins, it is still a poorly understood phenomenon. Limited studies show that the magnitude of reserve growth is controlled by several major factors, including (1) the reserve booking and reporting requirements in each country, (2) improvements in reservoir characterization and simulation, (3) application of enhanced oil recovery techniques, and (4) the discovery of new and extensions of known pools in discovered fields. Various combinations of these factors can affect the estimates of proven reserves in particular fields and may dictate repeated estimations of reserves during a field's life. This study explores the reserve growth in the 42 largest oil fields in the West Siberian Basin, which contain about 55 percent of the basin's total oil reserves. The West Siberian Basin occupies a vast swampy plain between the Ural Mountains and the Yenisey River, and extends offshore into the Kara Sea; it is the richest petroleum province in Russia. About 600 oil and gas fields with original reserves of 144 billion barrels of oil (BBO) and more than 1,200 trillion cubic feet of gas (TCFG) have been discovered. The principal oil reserves and most of the oil fields are in the southern half of the basin, whereas the northern half contains mainly gas reserves. Sedimentary strata in the basin consist of Upper Triassic through Tertiary clastic rocks. Most oil is produced from Neocomian (Lower Cretaceous) marine to deltaic sandstone reservoirs, although substantial oil reserves are also in the marine Upper Jurassic and continental to paralic Lower to Middle Jurassic sequences. The majority of oil fields are in structural traps, which are gentle, platform-type anticlines with closures ranging from several tens of meters to as much as 150 meters (490 feet). Fields producing from stratigraphic traps are generally smaller except for the giant Talin field which

Offer of secondary reserve with a pool of electric vehicles on the German market

International Nuclear Information System (INIS)

Jargstorf, Johannes; Wickert, Manuel

2013-01-01

This paper analyzes the business case of offering secondary downward reserve for frequency control on the German market by a pool of electrical vehicles. Former benchmark studies promised high revenues especially for this case. The benefits could provide an incentive to customers to buy an electric vehicle. The business case is analyzed for the German market as a case study. Specific regulations for this market, real driving patterns and real market data are taken into account when calculating revenues. Secondary reserve is strictly regulated, requiring a very high level of availability. As a result, simulated revenues are lower than assumed. Simulation shows average revenues of less than 5€ per month and vehicle. As a major bottleneck for an offer of secondary reserve, fully charged batteries are identified. Additionally an issue is made of costs for communication and customer compensation. Based on the simulation results, it is argued that the market for secondary reserve should not be accessed with these small units. For electric vehicles, easier accessible markets with lower related costs should be considered instead. -- Highlights: •We analyze a business case of providing reserve power with electric vehicles. •We include legal regulations for providing reserve power in the calculation. •Reserve requirements lead to a significant drop in expected revenues. •Results show that vehicles are not suitable to offer reserve power

TU-FG-BRB-02: The Impact of Using Dual-Energy CT for Determining Proton Stopping Powers: Comparison Between Theory and Experiments

Energy Technology Data Exchange (ETDEWEB)

Baer, E; Jee, K [Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts (United States); Zhang, R; Yang, K; Sharp, G; Liu, B [Massachusetts General Hospital, Boston, MA (United States); Lalonde, A [University of Montreal, Montreal, QC (Canada); Royle, G [University College London, London, London (United Kingdom); Bouchard, H [Universite de Montreal, Montreal, QC (Canada); Lu, H [Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States)

2016-06-15

Purpose: To evaluate the clinical performance of dual-energy CT (DECT) in determining proton stopping power ratios (SPR) and demonstrate advantages over conventional single-energy CT (SECT). Methods: SECT and DECT scans of tissue-equivalent plastics as well as animal meat samples are performed with a Siemens SOMATOM Definition Flash. The methods of Schneider et al. (1996) and Bourque et al. (2014) are used to determine proton SPR on SECT and DECT images, respectively. Waterequivalent path length (WEPL) measurements of plastics and tissue samples are performed with a 195 MeV proton beam. WEPL values are determined experimentally using the depth-dose shift and dose extinction methods. Results: Comparison between CT-based and experimental WEPL is performed for 12 tissue-equivalent plastic as well as 6 meat boxes containing animal liver, kidney, heart, stomach, muscle and bones. For plastic materials, results show a systematic improvement in determining SPR with DECT, with a mean absolute error of 0.4% compared to 1.7% for SECT. For the meat samples, preliminary results show the ability for DECT to determine WEPL with a mean absolute value of 1.1% over all meat boxes. Conclusion: This work demonstrates the potential in using DECT for determining proton SPR with plastic materials in a clinical context. Further work is required to show the benefits of DECT for tissue samples. While experimental uncertainties could be a limiting factor to show the benefits of DECT over SECT for the meat samples, further work is required to adapt the DECT formalism in the context of clinical use, where noise and artifacts play an important role.

TU-FG-BRB-02: The Impact of Using Dual-Energy CT for Determining Proton Stopping Powers: Comparison Between Theory and Experiments

International Nuclear Information System (INIS)

Baer, E; Jee, K; Zhang, R; Yang, K; Sharp, G; Liu, B; Lalonde, A; Royle, G; Bouchard, H; Lu, H

2016-01-01

Purpose: To evaluate the clinical performance of dual-energy CT (DECT) in determining proton stopping power ratios (SPR) and demonstrate advantages over conventional single-energy CT (SECT). Methods: SECT and DECT scans of tissue-equivalent plastics as well as animal meat samples are performed with a Siemens SOMATOM Definition Flash. The methods of Schneider et al. (1996) and Bourque et al. (2014) are used to determine proton SPR on SECT and DECT images, respectively. Waterequivalent path length (WEPL) measurements of plastics and tissue samples are performed with a 195 MeV proton beam. WEPL values are determined experimentally using the depth-dose shift and dose extinction methods. Results: Comparison between CT-based and experimental WEPL is performed for 12 tissue-equivalent plastic as well as 6 meat boxes containing animal liver, kidney, heart, stomach, muscle and bones. For plastic materials, results show a systematic improvement in determining SPR with DECT, with a mean absolute error of 0.4% compared to 1.7% for SECT. For the meat samples, preliminary results show the ability for DECT to determine WEPL with a mean absolute value of 1.1% over all meat boxes. Conclusion: This work demonstrates the potential in using DECT for determining proton SPR with plastic materials in a clinical context. Further work is required to show the benefits of DECT for tissue samples. While experimental uncertainties could be a limiting factor to show the benefits of DECT over SECT for the meat samples, further work is required to adapt the DECT formalism in the context of clinical use, where noise and artifacts play an important role.

Evaluation of flexible demand-side load-following reserves in power systems with high wind generation penetration

NARCIS (Netherlands)

Paterakis, N.G.; Catalao, J.P.S.; Ntomaris, A.V.; Erdinc, O.

2015-01-01

In this study, a two-stage stochastic programming joint energy and reserve day-ahead market structure is proposed in order to procure the required load-following reserves to tackle with wind power production uncertainty. Reserves can be procured both from generation and demand-side. Responsive

Improvements to the quality of the estimates of US uranium reserves

International Nuclear Information System (INIS)

Nikodem, Z.D.

1998-01-01

Extensive work has been done in the United States in the estimation of uranium reserves. The government's role in uranium raw materials shifted from support of military programmes to assessing the supply available for commercial power generation. A comprehensive system evolved in which government staff estimated reserves for each property over a range of cost levels using standardized estimation methodology and criteria. The programme was assigned to the Energy Information Administration (EIA) of the Department of Energy in 1983 which has the responsibility for reporting on energy resources. As uranium supply had increased and demand had decreased, there was less concern about the adequacy of resources. In this situation, and with reduced staffing levels, the EIA adopted a two part interim approach to preparing reserve estimates. One used questionnaires to obtain uranium company estimates of their economic and subeconomic reserves, with company determined economic criteria. A second approach modified the earlier detailed government property estimates to account for production. The EIA developed a new system with the assistance of consultants and the uranium industry. The goal of the new system is to produce one set of estimates at various cost categories for each property based on a rigorous adherence to EIA criteria. Initial information is gathered from the industry through a revised annual questionnaire. Company estimates that conform to EIA standards are incorporated into the EIA reserve data base. Additional information is gathered for those estimates requiring clarification, primarily through detailed technical conferences with company staff. The EIA has the capability to prepare independent reserve estimates from basic drill hole data when required. Uranium reserves estimated for 1990 by the EIA include the initial results from the new methodology. The cooperation and support of the uranium industry have been excellent. Detailed evaluation of properties is

A Sensorless Power Reserve Control Strategy for Two-Stage Grid-Connected PV Systems

OpenAIRE

Sangwongwanich, Ariya; Yang, Yongheng; Blaabjerg, Frede

2017-01-01

Due to the still increasing penetration of grid-connected Photovoltaic (PV) systems, advanced active power control functionalities have been introduced in grid regulations. A power reserve control, where namely the active power from the PV panels is reserved during operation, is required for grid support. In this paper, a cost-effective solution to realize the power reserve for two-stage grid-connected PV systems is proposed. The proposed solution routinely employs a Maximum Power Point Track...

An in-situ real-time optical fiber sensor based on surface plasmon resonance for monitoring the growth of TiO2 thin films.

Science.gov (United States)

Tsao, Yu-Chia; Tsai, Woo-Hu; Shih, Wen-Ching; Wu, Mu-Shiang

2013-07-23

An optical fiber sensor based on surface plasmon resonance (SPR) is proposed for monitoring the thickness of deposited nano-thin films. A side-polished multimode SPR optical fiber sensor with an 850 nm-LD is used as the transducing element for real-time monitoring of the deposited TiO2 thin films. The SPR optical fiber sensor was installed in the TiO2 sputtering system in order to measure the thickness of the deposited sample during TiO2 deposition. The SPR response declined in real-time in relation to the growth of the thickness of the TiO2 thin film. Our results show the same trend of the SPR response in real-time and in spectra taken before and after deposition. The SPR transmitted intensity changes by approximately 18.76% corresponding to 50 nm of deposited TiO2 thin film. We have shown that optical fiber sensors utilizing SPR have the potential for real-time monitoring of the SPR technology of nanometer film thickness. The compact size of the SPR fiber sensor enables it to be positioned inside the deposition chamber, and it could thus measure the film thickness directly in real-time. This technology also has potential application for monitoring the deposition of other materials. Moreover, in-situ real-time SPR optical fiber sensor technology is in inexpensive, disposable technique that has anti-interference properties, and the potential to enable on-line monitoring and monitoring of organic coatings.

78 FR 30245 - Electric Reliability Organization Interpretation of Specific Requirements of the Disturbance...

Science.gov (United States)

2013-05-22

... contingency reserve policy; and (3) refers to the ERO rather than the NERC Operating Committee in Requirements... the proposed interpretation, Requirements R3 and R4 provide: R3. Each Balancing Authority or Reserve... Requirement R4 requires that: ``[A] Balancing Authority or Reserve Sharing Group shall meet the Disturbance...

Moisture movement in soils on the Hanford Reservation

International Nuclear Information System (INIS)

Brownell, L.E.; Isaacson, R.E.; Sloughter, J.P.; Veatch, M.D.

1971-01-01

Methods being studied are as follows: the thermodynamic method based on water potential and thermocouple psychrometers; the tracer method using atmospheric tritium; the annual water balance based on the annual heat balance; the field lysimeter using thermocouple psychrometers; the influence of soil breathing as a result of changes in barometric pressure; and the influence of soil stratification. Progress to date has involved the installation of thermocouple psychrometers from the surface to the water table 310 feet below. These instruments are in the process of equilibration. Isothermal methods of analyzing water potential must be extended to include nonisothermal conditions which are dominant at the Hanford Reservation. Tracer techniques using tritium analyses of soil samples have successfully demonstrated that archaic water exists in virgin soil at the Hanford Reservation from a depth of approximately 7 meters to the water table, indicating that percolation has been limited to lesser depths. The annual heat balance indicates that quantities of water many times greater than the annual average precipitation of 16 centimeters can be evaporated from the soils at the Hanford Reservation during a normal summer. This indicates that the critical precipitation (P/sub c/) value may be greater than 30 to 50 centimeters of water. More precise values of the Bowen's ratio for the Hanford Reservation are required to refine this computation. The field lysimeter is perhaps the most direct method of determining the critical precipitation values for the Hanford Reservation but as yet has not been used

Chicle harvesting and extractive reserves in the Maya Biosphere b: Reserve

Energy Technology Data Exchange (ETDEWEB)

Dugelby, B.L.

1995-12-31

Chicle latex has been extracted from the forests of northern Guatemala for over 100 years and is a key element in the extractive reserve component of the Maya Biosphere Reserve. The carrying capacity of the reserve for chicle extraction can be estimated from a model incorporating ecological data (such as latex yields per tree and population structure of chicle trees, Manilkara zapota, Sapot.) with socio-ecological and political information concerning camp and chicle resource availability, harvester tapping behavior, and historical and present-day institutional organization. I estimate that chicle harvestors currently utilize and area larger than the multiple use zone of the reserve in a unsustainable manner. Simple reduction of harvestors numbers will not ensure sustainability; institutional reforms are also in order. Extractive reserves can play an important role in preserving tropical forests. However, their effectiveness is highly dependent on prevailing ecological, socio-economic, and political conditions. Wise planning and management of extractive reserves demands an understanding of the system`s carrying capacity. In addition, a strong institutional foundation is necessary to assure effective monitoring and enforcement of harvesting regulations.

7 CFR 1942.117 - General requirements.

Science.gov (United States)

2010-01-01

... § 1942.117 General requirements. (a) Reserve requirements. Loans under this subpart are subject to the... 7 Agriculture 13 2010-01-01 2009-01-01 true General requirements. 1942.117 Section 1942.117 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...

Design and initial performance of the Sandia Pulsed Reactor-III

International Nuclear Information System (INIS)

Reuscher, J.A.; Estes, B.F.

1976-01-01

The Sandia Pulsed Reactor-III (SPR-III) is a new fast pulsed reactor which has recently undergone initial testing at Sandia Laboratories. SPR-III is a uranium-10 weight percent molybdenum fuel assembly with a 17.78 cm irradiation cavity similar in design to SPR-II which has been in operation since 1967. The basic SPR-III design utilizes the same split-core configuration which has been proven with SPR-II; however, SPR-III uses external reflectors for control and external bolts to hold the fuel plates together. The core consists of sixteen fuel plates with an inside diameter of 17.78 cm, an outside diameter of 29.72 cm, and a core height of 31.9 cm. The fuel mass is about 227 kg of fully enriched uranium-10 weight percent molybdenum alloy. SPR III has completed the initial series of startup tests which included the critical experiment, zero and low-power tests, and pulse testing. The reactor design and results from the initial testing program are described in this paper. A portion of the startup experiments with SPR-III have been completed and this paper discusses the more important aspects of the initial testing program

Surface Plasmon Resonance: New Biointerface Designs and High-Throughput Affinity Screening

Science.gov (United States)

Linman, Matthew J.; Cheng, Quan Jason

Surface plasmon resonance (SPR) is a surface optical technique that measures minute changes in refractive index at a metal-coated surface. It has become increasingly popular in the study of biological and chemical analytes because of its label-free measurement feature. In addition, SPR allows for both quantitative and qualitative assessment of binding interactions in real time, making it ideally suited for probing weak interactions that are often difficult to study with other methods. This chapter presents the biosensor development in the last 3 years or so utilizing SPR as the principal analytical technique, along with a concise background of the technique itself. While SPR has demonstrated many advantages, it is a nonselective method and so, building reproducible and functional interfaces is vital to sensing applications. This chapter, therefore, focuses mainly on unique surface chemistries and assay approaches to examine biological interactions with SPR. In addition, SPR imaging for high-throughput screening based on microarrays and novel hyphenated techniques involving the coupling of SPR to other analytical methods is discussed. The chapter concludes with a commentary on the current state of SPR biosensing technology and the general direction of future biosensor research.

Pricing of reserves. Valuing system reserve capacity against spot prices in electricity markets

International Nuclear Information System (INIS)

Just, Sebastian; Weber, Christoph

2008-01-01

This paper models the interdependencies between markets for secondary reserve capacity and spot electricity to derive the pricing of reserves under equilibrium conditions. Starting with the indifference condition between offering in both markets, the reservation price is derived from the opportunity cost consideration and the unit commitment conditions in a fundamental interrelated market framework. The reserve market examined compares widely to the German market for secondary reserves, but the general approach may also be used to investigate other reserve markets. The approach explores and formalizes the influence of reserve capacity on the spot market supply function. A numerical solution procedure is provided to this non-trivial case of market interaction. The model is used to estimate the expected reservation price development over the last years in Germany. (author)

FASB statement 121 and other accounting issues affecting reserves reporting; CD-ROM ed.

Energy Technology Data Exchange (ETDEWEB)

Rowden, K R [Currie Coopers and Lybrand, Toronto, ON (Canada)

1996-03-01

The provisions required by FASB 121, and their impact on oil and gas properties, were explained. This included the impact of FASB statement 121, accounting for the impairment of long-lived assets and for assets to be disposed of on oil and gas properties. A two-tiered approach to recognition and measurement was described, as well as how reserve estimates are used for measurement of impairment. Reserve reports were considered to be the basis for financial statement disclosure. Procedures for reporting of finding costs and acquisition costs according to FASB 69 were described, and the Securities and Exchange Commission (SEC) reporting requirements were summarized.

SANSMIC design document.

Energy Technology Data Exchange (ETDEWEB)

Weber, Paula D. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Rudeen, David Keith [GRAM, Inc., Albuquerque, NM (United States)

2015-07-01

The United States Strategic Petroleum Reserve (SPR) maintains an underground storage system consisting of caverns that were leached or solution mined in four salt domes located near the Gulf of Mexico in Texas and Louisiana. The SPR comprises more than 60 active caverns containing approximately 700 million barrels of crude oil. Sandia National Labo- ratories (SNL) is the geotechnical advisor to the SPR. As the most pressing need at the inception of the SPR was to create and fill storage volume with oil, the decision was made to leach the caverns and fill them simultaneously (leach-fill). Therefore, A.J. Russo developed SANSMIC in the early 1980s which allows for a transient oil-brine interface (OBI) making it possible to model leach-fill and withdrawal operations. As the majority of caverns are currently filled to storage capacity, the primary uses of SANSMIC at this time are related to the effects of small and large withdrawals, expansion of existing caverns, and projecting future pillar to diameter ratios. SANSMIC was identified by SNL as a priority candidate for qualification. This report continues the quality assurance (QA) process by documenting the "as built" mathematical and numerical models that comprise this document. The pro- gram flow is outlined and the models are discussed in detail. Code features that were added later or were not documented previously have been expounded. No changes in the code's physics have occurred since the original documentation (Russo, 1981, 1983) although recent experiments may yield improvements to the temperature and plume methods in the future.

Surfactant protein A (SP-A)-mediated clearance of Staphylococcus aureus involves binding of SP-A to the staphylococcal adhesin eap and the macrophage receptors SP-A receptor 210 and scavenger receptor class A.

Science.gov (United States)

Sever-Chroneos, Zvjezdana; Krupa, Agnieszka; Davis, Jeremy; Hasan, Misbah; Yang, Ching-Hui; Szeliga, Jacek; Herrmann, Mathias; Hussain, Muzafar; Geisbrecht, Brian V; Kobzik, Lester; Chroneos, Zissis C

2011-02-11

Staphylococcus aureus causes life-threatening pneumonia in hospitals and deadly superinfection during viral influenza. The current study investigated the role of surfactant protein A (SP-A) in opsonization and clearance of S. aureus. Previous studies showed that SP-A mediates phagocytosis via the SP-A receptor 210 (SP-R210). Here, we show that SP-R210 mediates binding and control of SP-A-opsonized S. aureus by macrophages. We determined that SP-A binds S. aureus through the extracellular adhesin Eap. Consequently, SP-A enhanced macrophage uptake of Eap-expressing (Eap(+)) but not Eap-deficient (Eap(-)) S. aureus. In a reciprocal fashion, SP-A failed to enhance uptake of Eap(+) S. aureus in peritoneal Raw264.7 macrophages with a dominant negative mutation (SP-R210(DN)) blocking surface expression of SP-R210. Accordingly, WT mice cleared infection with Eap(+) but succumbed to sublethal infection with Eap- S. aureus. However, SP-R210(DN) cells compensated by increasing non-opsonic phagocytosis of Eap(+) S. aureus via the scavenger receptor scavenger receptor class A (SR-A), while non-opsonic uptake of Eap(-) S. aureus was impaired. Macrophages express two isoforms: SP-R210(L) and SP-R210(S). The results show that WT alveolar macrophages are distinguished by expression of SP-R210(L), whereas SR-A(-/-) alveolar macrophages are deficient in SP-R210(L) expressing only SP-R210(S). Accordingly, SR-A(-/-) mice were highly susceptible to both Eap(+) and Eap(-) S. aureus. The lungs of susceptible mice generated abnormal inflammatory responses that were associated with impaired killing and persistence of S. aureus infection in the lung. In conclusion, alveolar macrophage SP-R210(L) mediates recognition and killing of SP-A-opsonized S. aureus in vivo, coordinating inflammatory responses and resolution of S. aureus pneumonia through interaction with SR-A.

Czech fiasco with oil reserves has not deterred Slovakia

International Nuclear Information System (INIS)

Haluza, I.

2004-01-01

In order to meet its obligation to keep a 90-day emergency reserve of oil and oil products, Slovakia must purchase about 40% of the required volume of these commodities and complete storage capacity for the reserves. In addition, it must also create a system of storage management for the reserves including a regular exchange of the contents of the tanks. If it does not meet the 2008 deadline, EU structural funds will be decreased. In order to create the missing storage capacity, the Sprava statnych hmotnych rezerv (SSHR - Administration of Public Material Reserves) is considering a solution which Slovnaft, a.s. sees as a major risk for the state. Should the hundreds of millions needed for the building of new tanks not be found in the budget, the state would invite private investors to build the tanks, stated SSHR Chairman, Jan Tusim. Private investors will not endanger public control over the emergency reserves. Other countries also lease tanks. But according to information provided by its chairman, SSHR also wants to make the private investors responsible for the regular exchange of the emergency reserves that must be carried out every four to five years. Given an accurate forecast of price development on international markets, a lot of money can be made on these exchanges. Slovnaft stresses that if the state were no longer responsible for the exchange of the tanks' contents, it would be the state that was at risk not the refineries

Insight on agglomerates of gold nanoparticles in glass based on surface plasmon resonance spectrum: study by multi-spheres T-matrix method

Science.gov (United States)

Avakyan, L. A.; Heinz, M.; Skidanenko, A. V.; Yablunovski, K. A.; Ihlemann, J.; Meinertz, J.; Patzig, C.; Dubiel, M.; Bugaev, L. A.

2018-01-01

The formation of a localized surface plasmon resonance (SPR) spectrum of randomly distributed gold nanoparticles in the surface layer of silicate float glass, generated and implanted by UV ArF-excimer laser irradiation of a thin gold layer sputter-coated on the glass surface, was studied by the T-matrix method, which enables particle agglomeration to be taken into account. The experimental technique used is promising for the production of submicron patterns of plasmonic nanoparticles (given by laser masks or gratings) without damage to the glass surface. Analysis of the applicability of the multi-spheres T-matrix (MSTM) method to the studied material was performed through calculations of SPR characteristics for differently arranged and structured gold nanoparticles (gold nanoparticles in solution, particles pairs, and core-shell silver-gold nanoparticles) for which either experimental data or results of the modeling by other methods are available. For the studied gold nanoparticles in glass, it was revealed that the theoretical description of their SPR spectrum requires consideration of the plasmon coupling between particles, which can be done effectively by MSTM calculations. The obtained statistical distributions over particle sizes and over interparticle distances demonstrated the saturation behavior with respect to the number of particles under consideration, which enabled us to determine the effective aggregate of particles, sufficient to form the SPR spectrum. The suggested technique for the fitting of an experimental SPR spectrum of gold nanoparticles in glass by varying the geometrical parameters of the particles aggregate in the recurring calculations of spectrum by MSTM method enabled us to determine statistical characteristics of the aggregate: the average distance between particles, average size, and size distribution of the particles. The fitting strategy of the SPR spectrum presented here can be applied to nanoparticles of any nature and in various

MO-FG-CAMPUS-JeP1-04: Evaluating DECT Vs SECT Range Differences in Proton Therapy Using Clinical Data

Energy Technology Data Exchange (ETDEWEB)

Hudobivnik, N; Dedes, G; Parodi, K; Landry, G [Ludwig-Maximilians-Universitaet Muenchen, Garching (Germany); Schwarz, F; Johnson, T; Thieke, C; Belka, C; Sommer, W [LMU Munich, Munich (Germany); Tessonnier, T [Ludwig-Maximilians-Universitaet Muenchen, Garching (Germany); Universitaetsklinikum Heidelberg, Heidelberg (Germany); Verhaegen, F [Maastro Clinic, Maastricht (Netherlands)

2016-06-15

Purpose: Range uncertainty from X-ray CT number conversion to stopping power ratio (SPR) is one of the key factors limiting the potential of proton therapy. The large margins required for deep seated tumors degrade the organ sparing achievable with the technology. Of interest is the application of dual energy CT (DECT) to SPR estimation. In this planning study proton range differences between SECT and DECT have been quantified for brain cases. Methods: A last generation dual source DECT scanner was used to acquire SECT (150 kVp with Sn filtration) and DECT (additionally 90 kVp) scans of phantoms and 5 head trauma patients, acting as surrogate cancer patients. Phantom materials were characterized in terms of SPR in a particle beam to obtain reference values. IMPT treatment plans were generated on the basis of SECT and DECT SPR images for hypothetical brain tumors using a short and a long beam path. Range differences between SECT and DECT from plan recalculations were evaluated in beam-eye-view (BEV) by comparing the 80% isodose. Results: For the 18 phantom materials the SECT RMS SPR errors were 2.6% compared to 1.1% for DECT. Group median relative range differences between SECT and DECT plans were −1.0% for the short beam path over the 5 patients investigated in this study. For the long beam path the median difference was −1.4%. These relative range differences corresponded to −0.5 mm and −1.4 mm shifts respectively. Conclusion: This is the first study performing proton therapy treatment planning on DECT patient images. Important range differences of more than 1 mm were observed between SECT and DECT treatment plans, and DECT SPR accuracy was found superior on the basis of phantom measurements. While the patients investigated in this study did not have brain tumors, the findings we observed should apply to cancer patients. Deutsche Forschungsgemeinschaft (MAP); Bundesministerium fur Bildung und Forschung (01IB13001)

The design and development of GRASS file reservation system

International Nuclear Information System (INIS)

Huang Qiulan; Zhu Suijiang; Cheng Yaodong; Chen Gang

2010-01-01

GFRS (GRASS File Reservation System) is designed to improve the file access performance of GRASS (Grid-enabled Advanced Storage System) which is a Hierarchical Storage Management (HSM) system developed at Computing Center, Institute of High Energy Physics. GRASS can provide massive storage management and data migration, but the data migration policy is simply based factors such as pool water level, the intervals for migration and so on, so it is short of precise control over files. As for that, we design GFRS to implement user-based file reservation which is to reserve and keep the required files on disks for High Energy physicists. CFRS can improve file access speed for users by avoiding migrating frequently accessed files to tapes. In this paper we first give a brief introduction of GRASS system and then detailed architecture and implementation of GFRS. Experiments results from GFRS have shown good performance and a simple analysis is made based on it. (authors)

Creation of Power Reserves Under the Market Economy Conditions

Science.gov (United States)

Mahnitko, A.; Gerhards, J.; Lomane, T.; Ribakov, S.

2008-09-01

The main task of the control over an electric power system (EPS) is to ensure reliable power supply at the least cost. In this case, requirements to the electric power quality, power supply reliability and cost limitations on the energy resources must be observed. The available power reserve in an EPS is the necessary condition to keep it in operation with maintenance of normal operating variables (frequency, node voltage, power flows via the transmission lines, etc.). The authors examine possibilities to create power reserves that could be offered for sale by the electric power producer. They consider a procedure of price formation for the power reserves and propose a relevant mathematical model for a united EPS, the initial data being the fuel-cost functions for individual systems, technological limitations on the active power generation and consumers' load. As the criterion of optimization the maximum profit for the producer is taken. The model is exemplified by a concentrated EPS. The computations have been performed using the MATLAB program.

Reserve Component Alignment with Law, Policy, and Strategy

Science.gov (United States)

2011-02-07

10 addressed the Armed Forces; Title 32, the National Guard; and Title 34, the Navy. However, these laws were enacted as “ prima facie ” evidence only... Duty members available to accomplish a mission. The implication is that all of these conditions are temporary and that the reserves are to be...when national security requires it, or (4) when there are insufficient Active Duty members available to accomplish a mission. The implication is

Phase sensitive spectral domain interferometry for label free biomolecular interaction analysis and biosensing applications

Science.gov (United States)

Chirvi, Sajal

Biomolecular interaction analysis (BIA) plays vital role in wide variety of fields, which include biomedical research, pharmaceutical industry, medical diagnostics, and biotechnology industry. Study and quantification of interactions between natural biomolecules (proteins, enzymes, DNA) and artificially synthesized molecules (drugs) is routinely done using various labeled and label-free BIA techniques. Labeled BIA (Chemiluminescence, Fluorescence, Radioactive) techniques suffer from steric hindrance of labels on interaction site, difficulty of attaching labels to molecules, higher cost and time of assay development. Label free techniques with real time detection capabilities have demonstrated advantages over traditional labeled techniques. The gold standard for label free BIA is surface Plasmon resonance (SPR) that detects and quantifies the changes in refractive index of the ligand-analyte complex molecule with high sensitivity. Although SPR is a highly sensitive BIA technique, it requires custom-made sensor chips and is not well suited for highly multiplexed BIA required in high throughput applications. Moreover implementation of SPR on various biosensing platforms is limited. In this research work spectral domain phase sensitive interferometry (SD-PSI) has been developed for label-free BIA and biosensing applications to address limitations of SPR and other label free techniques. One distinct advantage of SD-PSI compared to other label-free techniques is that it does not require use of custom fabricated biosensor substrates. Laboratory grade, off-the-shelf glass or plastic substrates of suitable thickness with proper surface functionalization are used as biosensor chips. SD-PSI is tested on four separate BIA and biosensing platforms, which include multi-well plate, flow cell, fiber probe with integrated optics and fiber tip biosensor. Sensitivity of 33 ng/ml for anti-IgG is achieved using multi-well platform. Principle of coherence multiplexing for multi

A Reserve-based Method for Mitigating the Impact of Renewable Energy

Science.gov (United States)

Krad, Ibrahim

The fundamental operating paradigm of today's power systems is undergoing a significant shift. This is partially motivated by the increased desire for incorporating variable renewable energy resources into generation portfolios. While these generating technologies offer clean energy at zero marginal cost, i.e. no fuel costs, they also offer unique operating challenges for system operators. Perhaps the biggest operating challenge these resources introduce is accommodating their intermittent fuel source availability. For this reason, these generators increase the system-wide variability and uncertainty. As a result, system operators are revisiting traditional operating strategies to more efficiently incorporate these generation resources to maximize the benefit they provide while minimizing the challenges they introduce. One way system operators have accounted for system variability and uncertainty is through the use of operating reserves. Operating reserves can be simplified as excess capacity kept online during real time operations to help accommodate unforeseen fluctuations in demand. With new generation resources, a new class of operating reserves has emerged that is generally known as flexibility, or ramping, reserves. This new reserve class is meant to better position systems to mitigate severe ramping in the net load profile. The best way to define this new requirement is still under investigation. Typical requirement definitions focus on the additional uncertainty introduced by variable generation and there is room for improvement regarding explicit consideration for the variability they introduce. An exogenous reserve modification method is introduced in this report that can improve system reliability with minimal impacts on total system wide production costs. Another potential solution to this problem is to formulate the problem as a stochastic programming problem. The unit commitment and economic dispatch problems are typically formulated as deterministic

Peacekeeping: Is It Feasible to Expand the Role of the Reserve Components?

National Research Council Canada - National Science Library

Ball, Arley

1997-01-01

.... These documents form the basis of my analysis. In addition, leaders from both the Active and Reserve Components have provided me their assessments of past performance and future requirements of the citizen soldiers...

Strategic Petroleum Reserve annual report for calendar year 1998

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-12-31

The Strategic Petroleum Reserve was established in 1975 as an emergency response to the 1973 Arab oil embargo. It is authorized by the Energy Policy and Conservation Act (EPCA), and by the comprehensive energy plans of all Administrations since 1975, in recognition of the long-term dependence of the US on imported crude oil and petroleum products. Section 165 of EPCA requires the Secretary of Energy to submit an Annual Report to the President and the Congress. On May 13, 1998, the Department published a Statement of Administration Policy which reaffirmed its commitment to maintain a Government-owned and controlled, centrally located Strategic Petroleum Reserve of crude oil. The Reserve is to be used solely for responding to the types of severe oil supply interruptions presently contemplated in EPCA. Over the past twenty years, the Reserve has grown as large as 592 million barrels--a peak reached in 1994. From 1994 to 1996, nearly 28 million barrels were sold to raise revenues for the U S Treasury. As of December 31, 1998, the crude oil inventory was 561,108,127 barrels which equated to 60 days of net oil imports during 1998. The US now relies on a combination of both the Reserve and private stocks to meet its oil storage obligations to the International Energy Agency.

Analysis of the performance of interferometry, surface plasmon resonance and luminescence as biosensors and chemosensors

International Nuclear Information System (INIS)

Ince, R.; Narayanaswamy, R.

2006-01-01

Sensitivity, dynamic range and resolution have been calculated and compared from a range of analytes sensed in the literature using the techniques of interferometry, surface plasmon resonance (SPR) and luminescence. A detailed explanation of the physical and chemical/biological properties required of optical sensors is included along with the principle of operation of the sensors. Theoretical sensitivities of interferometry and SPR are also detailed along with parameters affecting these sensitivities. In the literature discussed in this review paper, the technique of luminescence, which relies intrinsically on 'labelling', offers the best resolutions for sensing of biomolecules (protein and DNA). Interference techniques offer the best resolutions for low molecular weight chemical liquids/vapours. Techniques which are 'label-free' are often desirable and it is demonstrated here that by combining the techniques of SPR with interferometry, it is possible to sense proteins with a resolution similar to that of luminescence. The future of chemo- and bio-sensing is discussed in terms of potential for multi-channel analysis, their continuous miniaturisation and their impending nanotechnology revolution

Protected reserves within tropical forests managed fortimber production: recommendations using Bolivia as a case study

NARCIS (Netherlands)

Fredericksen, T.S.; Peña Claros, M.

2007-01-01

The Bolivian forestry law requires that 10 per cent of areas under forest management must be set aside as 'ecological reserves', serving as protected areas from resource extraction. These guidelines appear to be based largely on reserve design theory from the conservation biology literature

29 CFR 1602.19 - Additional reporting requirements.

Science.gov (United States)

2010-07-01

....19 Additional reporting requirements. The Commission reserves the right to require reports, other... necessary to accomplish the purpose of title VII, the ADA, or GINA. Any system for the requirement of such... 29 Labor 4 2010-07-01 2010-07-01 false Additional reporting requirements. 1602.19 Section 1602.19...

29 CFR 1602.11 - Additional reporting requirements.

Science.gov (United States)

2010-07-01

... Additional reporting requirements. The Commission reserves the right to require reports, other than that... accomplish the purposes of title VII, the ADA, or GINA. Any system for the requirement of such reports will... 29 Labor 4 2010-07-01 2010-07-01 false Additional reporting requirements. 1602.11 Section 1602.11...

29 CFR 1602.26 - Additional reporting requirements.

Science.gov (United States)

2010-07-01

... Report § 1602.26 Additional reporting requirements. The Commission reserves the right to require reports... to accomplish the purposes of title VII, the ADA, or GINA. Any system for requirement of such reports... 29 Labor 4 2010-07-01 2010-07-01 false Additional reporting requirements. 1602.26 Section 1602.26...

HYDROCARBONS RESERVES IN VENEZUELA

Energy Technology Data Exchange (ETDEWEB)

Gonzalez Cruz, D.J.

2007-07-01

Venezuela is an important player in the energy world, because of its hydrocarbons reserves. The process for calculating oil and associated gas reserves is described bearing in mind that 90% of the gas reserves of Venezuela are associated to oil. Likewise, an analysis is made of the oil reserves figures from 1975 to 2003. Reference is also made to inconsistencies found by international experts and the explanations offered in this respect by the Ministry of Energy and Petroleum (MENPET) and Petroleos de Venezuela (PDVSA) regarding the changes that took place in the 1980s. In turn, Hubbert's Law is explained to determine peak production of conventional oil that a reservoir or field will reach, as well as its relationship with remaining reserves. Emphasis is placed on the interest of the United Nations on this topic. The reserves of associated gas are presented along with their relationship with the different crude oils that are produced and with injected gas, as well as with respect to the possible changes that would take place in the latter if oil reserves are revised. Some recommendations are submitted so that the MENPET starts preparing the pertinent policies ruling reserves. (auth)

Hurricanes

Science.gov (United States)

... and Practices Treatments That Work Screening and Assessment Psychological First Aid and SPR Core Curriculum on Childhood Trauma Trauma- ... Measure Reviews All Measure Reviews Usage and Glossary Psychological First Aid and SPR About PFA About SPR NCTSN Resources ...

Childhood Traumatic Grief

Science.gov (United States)

... and Practices Treatments That Work Screening and Assessment Psychological First Aid and SPR Core Curriculum on Childhood Trauma Trauma- ... Measure Reviews All Measure Reviews Usage and Glossary Psychological First Aid and SPR About PFA About SPR NCTSN Resources ...

INTERNATIONAL RESERVES, GUARANTEE THAT SUPPORTS ROMANIA'S ECONOMIC DEVELOPMENT

Directory of Open Access Journals (Sweden)

MEDAR LUCIAN-ION

2014-10-01

Full Text Available Aggregate demand in our country far exceeds the ability of the economy to produce goods and services. The gap between total demand for goods and services on the one hand and economic status, on the other hand stands out primarily by the continuing need for funds to cover the budget deficit. The Lack of foreign investors, poor development of capital market and non-involvement of credit institutions to support economic development leads the Romanian state to borrow regularly on international money market. Guarantor of the country for these loans is the reserve fund managed by the central bank of the state. Trade deficits and foreign borrowing are two components of the same problems. As the state borrows more from the international financial markets the higher is the trade deficit. A national initiative on facilities development companies with export production and aggregate demand for domestic products, can lead to lower imports. Increasing the fund's reserves and activation may be one of the solutions required to support economic development. Through this study we try to discover the role of the reserve fund and other sources of economic development.

US uranium reserves

International Nuclear Information System (INIS)

Hansen, M.V.

1981-01-01

The current low level of demand, compounded by rapidly rising costs and low prices, has caused a significant reduction in drilling for uranium in the United States, and the trend is likely to continue for a few more years. The effect on uranium reserves will be fewer additions to reserves because less exploration is being done. Further reductions will occur, especially in low-cost reserves, because of increasing costs, continuing depletion through production, and erosion through the high grading of deposits to fulfill previous contractual commitments. During the past several years, it has been necessary to increase the upper reserve cost level twice to compensate for rising costs. Rising costs are reducing the $15 reserves, the cost category corresponding most closely to the present market price, to an insignificant level. An encouraging factor related to US uranium reserves is that the US position internationally, as far as quantity is concerned, is not bad for the longer term. Also, there is a general opinion that US consumers would rather contract for domestic uranium than for foreign because of greater assurance of supply. Still another factor, nearly impossible to assess, is what effect rising costs in other countries will have on their uranium reserves. The annual conferences between the Grand Junction Area Office staff and major uranium companies provide a broad overview of the industry's perception of the future. It is not optimistic for the short term. Many companies are reducing their exploration and mining programs; some are switching to other more marketable mineral commodities, and a few are investing more heavily in foreign ventures. However, there is general optimism for the long term, and many predict a growth in demand in the mid-1980s. If the industry can survive the few lean years ahead, rising prices may restore its viability to former levels

A Sensorless Power Reserve Control Strategy for Two-Stage Grid-Connected PV Systems

DEFF Research Database (Denmark)

Sangwongwanich, Ariya; Yang, Yongheng; Blaabjerg, Frede

2017-01-01

Due to the still increasing penetration of grid-connected Photovoltaic (PV) systems, advanced active power control functionalities have been introduced in grid regulations. A power reserve control, where namely the active power from the PV panels is reserved during operation, is required for grid...... support. In this paper, a cost-effective solution to realize the power reserve for two-stage grid-connected PV systems is proposed. The proposed solution routinely employs a Maximum Power Point Tracking (MPPT) control to estimate the available PV power and a Constant Power Generation (CPG) control...... performed on a 3-kW two-stage single-phase grid-connected PV system, where the power reserve control is achieved upon demands....

12 CFR 609.915 - Compliance with Federal Reserve Board Regulations B, M, and Z.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Compliance with Federal Reserve Board Regulations B, M, and Z. 609.915 Section 609.915 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ELECTRONIC COMMERCE General Rules § 609.915 Compliance with Federal Reserve Board Regulations B, M, and Z. The regulations in this part require...

The incidental pulmonary nodule in a child. Part 1: recommendations from the SPR Thoracic Imaging Committee regarding characterization, significance and follow-up

Energy Technology Data Exchange (ETDEWEB)

Westra, Sjirk J. [Massachusetts General Hospital, Division of Pediatric Radiology, Boston, MA (United States); Brody, Alan S. [Cincinnati Children' s Hospital Medical Center, Department of Radiology (CH-1), Cincinnati, OH (United States); Mahani, Maryam Ghadimi [University of Michigan Health System, Section of Pediatric Radiology, C. S. Mott Children' s Hospital Department of Radiology, Ann Arbor, MI (United States); Guillerman, R.P. [Texas Children' s Hospital, Department of Radiology, Houston, TX (United States); Hegde, Shilpa V. [Arkansas Children' s Hospital, Department of Radiology, Little Rock, AR (United States); Iyer, Ramesh S. [Seattle Children' s Hospital, Department of Radiology, Seattle, WA (United States); Lee, Edward Y. [Boston Children' s Hospital, Department of Pediatric Radiology, Boston, MA (United States); Newman, Beverley [Lucile Packard Children' s Hospital at Stanford University, Department of Radiology, Stanford, CA (United States); Podberesky, Daniel J. [Nemours Children' s Hospital, Department of Radiology, Orlando, FL (United States); Thacker, Paul G. [Medical University of South Carolina, Department of Radiology, Charleston, SC (United States)

2015-05-01

No guidelines are in place for the follow-up and management of pulmonary nodules that are incidentally detected on CT in the pediatric population. The Fleischner guidelines, which were developed for the older adult population, do not apply to children. This review summarizes the evidence collected by the Society for Pediatric Radiology (SPR) Thoracic Imaging Committee in its attempt to develop pediatric-specific guidelines. Small pulmonary opacities can be characterized as linear or as ground-glass or solid nodules. Linear opacities and ground-glass nodules are extremely unlikely to represent an early primary or metastatic malignancy in a child. In our review, we found a virtual absence of reported cases of a primary pulmonary malignancy presenting as an incidentally detected small lung nodule on CT in a healthy immune-competent child. Because of the lack of definitive information on the clinical significance of small lung nodules that are incidentally detected on CT in children, the management of those that do not have the typical characteristics of an intrapulmonary lymph node should be dictated by the clinical history as to possible exposure to infectious agents, the presence of an occult immunodeficiency, the much higher likelihood that the nodule represents a metastasis than a primary lung tumor, and ultimately the individual preference of the child's caregiver. Nodules appearing in children with a history of immune deficiency, malignancy or congenital pulmonary airway malformation should not be considered incidental, and their workup should be dictated by the natural history of these underlying conditions. (orig.)

The Nature and Use of Copper Reserve and Resource Data

Science.gov (United States)

Cox, Dennis P.; Wright, Nancy A.; Coakley, George J.

1981-01-01

Copper reserve, resource, and production data can be combined to produce disaggregated resource estimates and trends and, when combined with demand forecasts, can be used to predict future exploration and development requirements. Reserve estimates are subject to uncertainties due mainly to incomplete exploration and rapidly changing economic conditions. United States' reserve estimates in the past have been low mainly because knowledge of the magnitude of very large porphyry-copper deposits has been incomplete. Present estimates are considerably more reliable because mining firms tend to drill out deposits fully before mining and to release their reserve estimates to the public. The sum of reserves and past production yields an estimate of the total ore, total metal contained in ore, and average grade of ore originally in each of the deposits known in the United States. For most deposits, estimates of total copper in ore are low relative to the total copper in mineralized rock, and many estimates are strongly affected by the economic behavior of mining firms. A better estimate of the real distribution of copper contained in deposits can be obtained by combining past production data with resource estimates. Copper resource data are disaggregated into categories that include resources in undeveloped deposits similar to those mined in the past, resources in mines closed because of unfavorable economic conditions, resources in deep deposits requiring high-cost mining methods, arid resources in deposits located in areas where environmental restrictions have contributed to delays in development. The largest resource is located in the five largest porphyry deposits. These deposits are now being mined but the resources are not included in the present mining plan. Resources in this last category will not contribute to supply until some future time when ores presently being mined are depleted. A high correlation exists between total copper contained in deposits and annual

Biodegradation of propargite by Pseudomonas putida, isolated from tea rhizosphere.

Science.gov (United States)

Sarkar, Soumik; Seenivasan, Subbiah; Asir, Robert Premkumar Samuel

2010-02-15

Biodegradation of miticide propargite was carried out in vitro by selected Pseudomonas strains isolated from tea rhizosphere. A total number of 13 strains were isolated and further screened based on their tolerance level to different concentrations of propargite. Five best strains were selected and further tested for their nutritional requirements. Among the different carbon sources tested glucose exhibited the highest growth promoting capacity and among nitrogen sources ammonium nitrate supported the growth to the maximum. The five selected Pseudomonas strain exhibited a range of degradation capabilities. Mineral salts medium (MSM) amended with glucose provided better environment for degradation with the highest degradation potential in strain SPR 13 followed by SPR 8 (71.9% and 69.0% respectively).

Fabrication, characterization and gas sensing properties of gold ...

Indian Academy of Sciences (India)

Sensors; surface plasmon resonance; gold nanoparticle; thin film. 1. Introduction ... mercial SPR systems (e.g., Reichert4SPR 4 Channel SPR system) ... for organic vapour injection. ..... [40] Im J, Sengupta S K, Baruch M F, Granz C D, Ammu S,.

West Hackberry Brine Disposal Project pre-discharge characterization. Final report

Energy Technology Data Exchange (ETDEWEB)

DeRouen, L.R.; Hann, R.W.; Casserly, D.M.; Giammona, C. (eds.)

1982-01-01

The physical, chemical and biological attributes are described for: (1) a coastal marine environment centered about a Department of Energy Strategic Petroleum Reserve (SPR) brine disposal site 11.4 km off the southwest coast of Louisiana; and (2) the lower Calcasieu and Sabine estuarine systems that provide leach waters for the SPR project. A three month sampling effort, February through April 1981, and previous investigations from the study area are integrated to establish baseline information for evaluation of impacts from brine disposal in the nearshore marine waters and from freshwater withdrawal from the coastal marsh of the Chenier Plain. January data are included for some tasks that sampled while testing and mobilizing their instruments prior to the February field effort. The study addresses the areas of physical oceanography, estuarine hydrology and hydrography, water and sediment quality, benthos, nekton, phytoplankton, zooplankton, and data management.

7 CFR 1780.11 - Service area requirements.

Science.gov (United States)

2010-01-01

..., maintenance, debt service, and reserve requirements. Such guarantees from developers will meet the... 7 Agriculture 12 2010-01-01 2010-01-01 false Service area requirements. 1780.11 Section 1780.11... AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS General Policies and Requirements § 1780.11 Service...

Unit commitment with probabilistic reserve: An IPSO approach

International Nuclear Information System (INIS)

Lee, Tsung-Ying; Chen, Chun-Lung

2007-01-01

This paper presents a new algorithm for solution of the nonlinear optimal scheduling problem. This algorithm is named the iteration particle swarm optimization (IPSO). A new index, called iteration best, is incorporated into particle swarm optimization (PSO) to improve the solution quality and computation efficiency. IPSO is applied to solve the unit commitment with probabilistic reserve problem of a power system. The outage cost as well as fuel cost of thermal units was considered in the unit commitment program to evaluate the level of spinning reserve. The optimal scheduling of on line generation units was reached while minimizing the sum of fuel cost and outage cost. A 48 unit power system was used as a numerical example to test the new algorithm. The optimal scheduling of on line generation units could be reached in the testing results while satisfying the requirement of the objective function

The Netherlands: development of oil and gas reserves

International Nuclear Information System (INIS)

1993-01-01

Oil was first discovered in The Netherlands in the late 1930s near The Hague. Later the larger onshore field at Schoonebeek was found. In the 1960s significant resources of oil were discovered in the Dutch sector of the North Sea. However onshore oil still provides about 20% of the nation's requirements. In the 1960s the vast size of the onshore Groningen gas field became apparent and its subsequent development has provided the Dutch with a huge source of wealth. In recent years the Dutch Continental Shelf has also yielded substantial reserves of gas, although these are not yet as important as the onshore gas reserves. Dutch Government policy is designed to encourage the development of smaller offshore gas fields thereby conserving the Gronigen field. Dutch oil and gas production, licensing and drilling activities are discussed, and the prospects for British suppliers is considered. (author)

Integrated Optic Surface Plasmon Resonance Measurements in a Borosilicate Glass Substrate

Directory of Open Access Journals (Sweden)

Antonino Parisi

2008-11-01

Full Text Available The surface plasmon resonance (SPR technique is a well-known optical method that can be used to measure the refractive index of organic nano-layers adsorbed on a thin metal film. Although there are many configurations for measuring biomolecular interactions, SPR-based techniques play a central role in many current biosensing experiments, since they are the most suited for sensitive and quantitative kinetic measurements. Here we give some results from the analysis and numerical elaboration of SPR data from integrated optics experiments in a particular borosilicate glass, chosen for its composition offering the rather low refractive index of 1.4701 at 633 nm wavelength. These data regard the flow over the sensing region (metal window of different solutions with refractive indexes in the range of interest (1.3÷1.5 for the detection of contaminants in aqueous solutions. After a discussion of the principles of SPR, of the metal window design optimization by means of optical interaction numerical modeling, and of waveguide fabrication techniques, we give a description of system setup and experimental results. Optimum gold film window thickness and width in this guided-wave configuration has been for the first time derived and implemented on an integrated optic prototype device. Its characterization is given by means of the real time waveguide output intensity measurements, which correspond to the interaction between the sensing gold thin film window and the flowing analyte. The SPR curve was subsequently inferred. Finally, a modified version of the device is reported, with channel waveguides arranged in a Y-junction optical circuit, so that laser source stability requirements are lowered by a factor of 85 dB, making possible the use of low cost sources in practical applications.

Optimal offering and allocation policies for wind power in energy and reserve markets

DEFF Research Database (Denmark)

Soares, Tiago; Jensen, Tue Vissing; Mazzi, Nicolo

2017-01-01

Cormick relaxation and piecewise linear decision rules are adapted and tested aiming to maximize the expected revenue for participating in both energy and reserve markets, while accounting for estimated balancing costs for failing to provide energy and reserve. A set of numerical examples, as well as a case study......Proliferation of wind power generation is increasingly making this power source an important asset in designs of energy and reserve markets. Intuitively, wind power producers will require the development of new offering strategies that maximize the expected profit in both energy and reserve markets...... of better forecast information from the different day-ahead and balancing stages, allowing different shares of energy and reserve in both stages. Under these assumptions, different mathematical methods able to deal with the uncertain nature of wind power generation, namely, stochastic programming, with Mc...

Recent revisions of phosphate rock reserves and resources: reassuring or misleading? An in-depth literature review of global estimates of phosphate rock reserves and resources

Science.gov (United States)

Edixhoven, J. D.; Gupta, J.; Savenije, H. H. G.

2013-09-01

Phosphate rock (PR) is a finite mineral indispensible for fertilizer production and a major pollutant. High grade PR is obtained from deposits which took millions of years to form and are gradually being depleted. Over the past three years, global PR reserves as reported by US Geological Survey (USGS) have seen a massive increase, from 16 000 Mt PR in 2010 to 65 000 Mt PR in 2011. The bulk of this four-fold increase is based on a 2010 report by International Fertilizer Development Center (IFDC), which increased Moroccan reserves from 5700 Mt PR as reported by USGS, to 51 000 Mt PR, reported as upgraded ("beneficiated") concentrate. IFDC used a starkly simplified classification compared to the classification used by USGS and proposed that agreement should be reached on PR resource terminology which should be as simple as possible. The report has profoundly influenced the PR scarcity debate, shifting the emphasis from depletion to the pollution angle of the phosphate problem. Various analysts adopted the findings of IFDC and USGS, and argued that that following depletion of reserves, uneconomic deposits (resources and occurrences) will remain available which will extend the lifetime of available deposits to thousands of years. Given the near total dependence of food production on PR, data on PR deposits must be transparent, comparable, reliable and credible. Based on an in-depth literature review, we analyze (i) how IFDC's simplified terminology compares to international best practice in resource classification and whether it is likely to yield data that meets the abovementioned requirements; (ii) whether the difference between ore reserves and reserves as concentrate is sufficiently noted in the literature, and (iii) whether the IFDC report and its estimate of PR reserves and resources is reliable. We conclude that, while there is a global development toward common criteria in resource reporting, IFDC's definitions contravene this development and - due to their

Microcontact imprinted surface plasmon resonance sensor for myoglobin detection

International Nuclear Information System (INIS)

Osman, Bilgen; Uzun, Lokman; Beşirli, Necati; Denizli, Adil

2013-01-01

In this study, we prepared surface plasmon resonance (SPR) sensor using the molecular imprinting technique for myoglobin detection in human serum. For this purpose, we synthesized myoglobin imprinted poly(hydroxyethyl methacrylate-N-methacryloyl-L-tryptophan methyl ester) [poly(HEMA-MATrp)] nanofilm on the surface of SPR sensor. We also synthesized non-imprinted poly(HEMA-MATrp) nanofilm without myoglobin for the control experiments. The SPR sensor was characterized with contact angle measurements, atomic force microscopy, X-ray photoelectron spectroscopy, and ellipsometry. We investigated the effectiveness of the sensor using the SPR system. We evaluated the ability of SPR sensor to sense myoglobin with myoglobin solutions (pH 7.4, phosphate buffer) in different concentration range and in the serum taken from a patient with acute myocardial infarction. We found that the Langmuir adsorption model was the most suitable for the sensor system. The detection limit was 87.6 ng/mL. In order to show the selectivity of the SPR sensor, we investigated the competitive detection of myoglobin, lysozyme, cytochrome c and bovine serum albumin. The results showed that the SPR sensor has high selectivity and sensitivity for myoglobin. - Highlights: • Micro-contact imprinted surface plasmon resonance sensor. • Real-time myoglobin detection in the serum taken from a patient with acute myocardial infarction • Reproducible results for consecutive myoglobin solution supplement • LOD and LOQ values of the SPR sensor were determined to be 26.3 and 87.6 ng/mL. • The SPR sensor has potential for myoglobin sensing during acute MI cases

Application of Long-Range Surface Plasmon Resonance for ABO Blood Typing

Directory of Open Access Journals (Sweden)

Wanida Tangkawsakul

2016-01-01

Full Text Available In this study, we demonstrate a long-range surface plasmon resonance (LR-SPR biosensor for the detection of whole cell by captured antigens A and B on the surface of red blood cells (RBCs as a model. The LR-SPR sensor chip consists of high-refractive index glass, a Cytop film layer, and a thin gold (Au film, which makes the evanescent field intensity and the penetration depth longer than conventional SPR. Therefore, the LR-SPR biosensor has improved capability for detecting large analytes, such as RBCs. The antibodies specific to blood group A and group B (Anti-A and Anti-B are covalently immobilized on a grafting self-assembled monolayer (SAM/Au surface on the biosensor. For blood typing, RBC samples can be detected by the LR-SPR biosensor through a change in the refractive index. We determined that the results of blood typing using the LR-SPR biosensor are consistent with the results obtained from the agglutination test. We obtained the lowest detection limits of 1.58 × 105 cells/ml for RBC-A and 3.83 × 105 cells/ml for RBC-B, indicating that the LR-SPR chip has a higher sensitivity than conventional SPR biosensors (3.3 × 108 cells/ml. The surface of the biosensor can be efficiently regenerated using 20 mM NaOH. In summary, as the LR-SPR technique is sensitive and has a simple experimental setup, it can easily be applied for ABO blood group typing.

Robust Allocation of Reserve Policies for a Multiple-Cell Based Power System

DEFF Research Database (Denmark)

Hu, Junjie; Lan, Tian; Heussen, Kai

2018-01-01

modifications. The LDR method can effectively adapt the participation factors of reserve providers to respond to system imbalance signals. The policies considered the covariance of historic system imbalance signals to reduce the overall reserve cost. When applying this method to the cell-based power system...... for a certain horizon, the influence of different time resolutions on policy-making is also investigated, which presents guidance for its practical application. The main results illustrate that: (a) the LDR-based method shows better performance, by producing smaller reserve costs compared to the costs given...... by a reference method; and (b) the cost index decreases with increased time intervals, however, longer intervals might result in insufficient reserves, due to low time resolution. On the other hand, shorter time intervals require heavy computational time. Thus, it is important to choose a proper time interval...

Land Use Manager Application Ensures Protectiveness Following Remediation on the Oak Ridge Reservation - 13355

Energy Technology Data Exchange (ETDEWEB)

Garland, Sid; Brown, Sally; Sims, Lynn [Restoration Services, Inc., P.O. Box 4699, Oak Ridge, Tennessee 37831 (United States); Darby, Jason [U.S. Department of Energy, Office of Environmental Management, Oak Ridge Site (United States)

2013-07-01

Long-term stewardship is the set of activities necessary to return contaminated land to safe and beneficial use. The activities include physical and legal controls to prevent inappropriate exposure to contamination left in place at a site. It is the longest phase of the Department of Energy's Environmental Management Program and ensures the protection of human health and the environment for varied end uses. At the Department of Energy's Oak Ridge Reservation an automated program has been developed and implemented that tracks the multitude of long-term stewardship activities. The Oak Ridge Reservation is a large site that currently has over 50 actions requiring long-term stewardship activities. The Oak Ridge Reservation consists primarily of three plant sites, and long-term stewardship will enable these sites to be leased to private entities (East Tennessee Technology Park), modernized for an evolving national security mission (Y-12 National Security Complex), and revitalized to continue multi-disciplinary research (Oak Ridge National Laboratory). The varied site end uses of the individual plant sites coupled with the multitude of controls required by leaving waste in place presents challenges. A single remedial action may include surveillance and maintenance activities, media monitoring, property record notices as well as physical controls such as fences and signs. Thus, the array of long-term stewardship activities is complex and intermingled (over 200 inspections each year at various frequencies are required currently) and requires an effective tracking program, termed the Land Use Manager. The Land Use Manager is a web-based data management application for use by personnel responsible for implementing, maintaining, and verifying engineering and land use controls on the Oak Ridge Reservation. The program is a data entry and tracking tool, as well as a notification tool. The status and performance of engineering and land use controls are checked annually

Land Use Manager Application Ensures Protectiveness Following Remediation on the Oak Ridge Reservation - 13355

International Nuclear Information System (INIS)

Garland, Sid; Brown, Sally; Sims, Lynn; Darby, Jason

2013-01-01

Long-term stewardship is the set of activities necessary to return contaminated land to safe and beneficial use. The activities include physical and legal controls to prevent inappropriate exposure to contamination left in place at a site. It is the longest phase of the Department of Energy's Environmental Management Program and ensures the protection of human health and the environment for varied end uses. At the Department of Energy's Oak Ridge Reservation an automated program has been developed and implemented that tracks the multitude of long-term stewardship activities. The Oak Ridge Reservation is a large site that currently has over 50 actions requiring long-term stewardship activities. The Oak Ridge Reservation consists primarily of three plant sites, and long-term stewardship will enable these sites to be leased to private entities (East Tennessee Technology Park), modernized for an evolving national security mission (Y-12 National Security Complex), and revitalized to continue multi-disciplinary research (Oak Ridge National Laboratory). The varied site end uses of the individual plant sites coupled with the multitude of controls required by leaving waste in place presents challenges. A single remedial action may include surveillance and maintenance activities, media monitoring, property record notices as well as physical controls such as fences and signs. Thus, the array of long-term stewardship activities is complex and intermingled (over 200 inspections each year at various frequencies are required currently) and requires an effective tracking program, termed the Land Use Manager. The Land Use Manager is a web-based data management application for use by personnel responsible for implementing, maintaining, and verifying engineering and land use controls on the Oak Ridge Reservation. The program is a data entry and tracking tool, as well as a notification tool. The status and performance of engineering and land use controls are checked annually for

76 FR 55890 - Cancellation of Supplemental Environmental Impact Statement for Ancillary Facilities for the...

Science.gov (United States)

2011-09-09

... (SPR). In April 2011, Congress rescinded all funding for the SPR expansion project. FOR FURTHER... included no new funding to continue SPR expansion efforts and proposed cancellation of previously... expansion project, DOE prepared an environmental impact statement for the Site Selection for the Expansion...

Nanoscale patterning of gold-coated optical fibers for improved plasmonic sensing

Science.gov (United States)

Antohe, Iulia; Spasic, Dragana; Delport, Filip; Li, Jiaqi; Lammertyn, Jeroen

2017-05-01

Merging surface plasmon resonance (SPR) to fiber optic (FO) technology has brought remarkable achievements in the field by offering attractive advantages over the conventional prism-based SPR platforms, such as simplicity, cost-effectiveness and miniaturization. However, the performance of the existing FO-SPR instruments mainly depends on the device surface condition and in particular on the structural aspect of the thin gold (Au) plasmonic film deposited on the FO substrate. In this work, a simple cost-effective colloidal lithography technique (CLT) was adapted and applied for the first time to the micrometer-sized FO substrate, to design end reflection-type FO-SPR sensors with periodic arrays of Au triangularly-shaped nanostructures on the Au mirror FO tip distal end. The nanopatterned FO-SPR sensor tips were afterwards subjected to refractometric measurements in a sucrose dilution series and subsequently compared with their non-patterned counterparts. It was observed that the spectral dips of the nanopatterned FO-SPR sensor tips were shifted towards longer wavelengths after CLT patterning. Moreover, the sensor sensitivity was improved with up to 25% compared to the conventional non-patterned FO-SPR devices. The obtained results represent important steps in the development of a new generation of FO-SPR sensors with improved performance, which can ultimately be used in various applications, ranging from food analysis and environmental monitoring, to health control and medical diagnosis.

Transferability of antibody pairs from ELISA to fiber optic surface plasmon resonance for infliximab detection

Science.gov (United States)

Van Stappen, Thomas; Lu, Jiadi; Bloemen, Maarten; Geukens, Nick; Spasic, Dragana; Delport, Filip; Verbiest, Thierry; Lammertyn, Jeroen; Gils, Ann

2015-03-01

Tumor necrosis factor (TNF)-alpha is a pleiotropic cytokine up-regulated in inflammatory bowel disease, rheumatoid arthritis and psoriasis. The introduction of anti-TNF drugs such as infliximab has revolutionized the treatment of these diseases. Recently, therapeutic drug monitoring (TDM) of infliximab has been introduced in clinical decision making to increase cost-efficiency. Nowadays, TDM is performed using radio-immunoassays, homogeneous mobility shift assays or ELISA. Unfortunately, these assays do not allow for in situ treatment optimization, because of the required sample transportation to centralized laboratories and the subsequent assay execution time. In this perspective, we evaluated the potential of fiber optic-surface plasmon resonance (FO-SPR). To achieve this goal, a panel of 55 monoclonal anti-infliximab antibodies (MA-IFX) was developed and characterized in-house, leading to the identification of nine different clusters. Based on this high diversity, 22 antibody pairs were selected and tested for their reactivity towards IFX, using one MA-IFX as capture and one MA-IFX for detection, in a sandwich type ELISA and FO-SPR. This study showed that the reactivity towards IFX of each antibody pair in ELISA is highly similar to its reactivity on FO-SPR, indicating that antibody pairs are easily transferable between both platforms. Given the fact that FO-SPR shows the potential for miniaturization and fast assay time, it can be considered a highly promising platform for on-site infliximab monitoring.

Energy efficacy used to score organic refuse pretreatment processes for hydrogen anaerobic production.

Science.gov (United States)

Ruggeri, Bernardo; Luongo Malave, Andrea C; Bernardi, Milena; Fino, Debora

2013-11-01

The production of hydrogen through Anaerobic Digestion (AD) has been investigated to verify the efficacy of several pretreatment processes. Three types of waste with different carbon structures have been tested to obtain an extensive representation of the behavior of the materials present in Organic Waste (OW). The following types of waste were selected: Sweet Product Residue (SPR), i.e., confectionary residue removed from the market after the expiration date, Organic Waste Market (OWM) refuse from a local fruit and vegetable market, and Coffee Seed Skin (CSS) waste from a coffee production plant. Several pretreatment processes have been applied, including physical, chemical, thermal, and ultrasonic processes and a combination of these processes. Two methods have been used for the SPR to remove the packaging, manual (SPR) and mechanical (SPRex). A pilot plant that is able to extrude the refuse to 200atm was utilized. Two parameters have been used to score the different pretreatment processes: efficiency (ξ), which takes into account the amount of energy produced in the form of hydrogen compared with the available energy embedded in the refuse, and efficacy (η), which compares the efficiency obtained using the pretreated refuse with that obtained using the untreated refuse. The best result obtained for the SPR was the basic pretreatment, with η=6.4, whereas the thermal basic pretreatment gave the highest value, η=17.0 for SPRex. The best result for the OWM was obtained through a combination of basic/thermal pretreatments with η=9.9; lastly, the CSS residue with ultrasonic pretreatment produced the highest quantity of hydrogen, η=5.2. Copyright © 2013 Elsevier Ltd. All rights reserved.

Can slide positivity rates predict malaria transmission?

Directory of Open Access Journals (Sweden)

Bi Yan

2012-04-01

Full Text Available Abstract Background Malaria is a significant threat to population health in the border areas of Yunnan Province, China. How to accurately measure malaria transmission is an important issue. This study aimed to examine the role of slide positivity rates (SPR in malaria transmission in Mengla County, Yunnan Province, China. Methods Data on annual malaria cases, SPR and socio-economic factors for the period of 1993 to 2008 were obtained from the Center for Disease Control and Prevention (CDC and the Bureau of Statistics, Mengla, China. Multiple linear regression models were conducted to evaluate the relationship between socio-ecologic factors and malaria incidence. Results The results show that SPR was significantly positively associated with the malaria incidence rates. The SPR (β = 1.244, p = 0.000 alone and combination (SPR, β = 1.326, p  Conclusion SPR is a strong predictor of malaria transmission, and can be used to improve the planning and implementation of malaria elimination programmes in Mengla and other similar locations. SPR might also be a useful indicator of malaria early warning systems in China.

Label free fragment screening using surface plasmon resonance as a tool for fragment finding - analyzing parkin, a difficult CNS target.

Directory of Open Access Journals (Sweden)

Karin Regnström

Full Text Available Surface Plasmon Resonance (SPR is rarely used as a primary High-throughput Screening (HTS tool in fragment-based approaches. With SPR instruments becoming increasingly high-throughput it is now possible to use SPR as a primary tool for fragment finding. SPR becomes, therefore, a valuable tool in the screening of difficult targets such as the ubiquitin E3 ligase Parkin. As a prerequisite for the screen, a large number of SPR tests were performed to characterize and validate the active form of Parkin. A set of compounds was designed and used to define optimal SPR assay conditions for this fragment screen. Using these conditions, more than 5000 pre-selected fragments from our in-house library were screened for binding to Parkin. Additionally, all fragments were simultaneously screened for binding to two off target proteins to exclude promiscuous binding compounds. A low hit rate was observed that is in line with hit rates usually obtained by other HTS screening assays. All hits were further tested in dose responses on the target protein by SPR for confirmation before channeling the hits into Nuclear Magnetic Resonance (NMR and other hit-confirmation assays.

Label-Enhanced Surface Plasmon Resonance: A New Concept for Improved Performance in Optical Biosensor Analysis

Directory of Open Access Journals (Sweden)

Niko Granqvist

2013-11-01

Full Text Available Surface plasmon resonance (SPR is a well-established optical biosensor technology with many proven applications in the study of molecular interactions as well as in surface and material science. SPR is usually applied in the label-free mode which may be advantageous in cases where the presence of a label may potentially interfere with the studied interactions per se. However, the fundamental challenges of label-free SPR in terms of limited sensitivity and specificity are well known. Here we present a new concept called label-enhanced SPR, which is based on utilizing strongly absorbing dye molecules in combination with the evaluation of the full shape of the SPR curve, whereby the sensitivity as well as the specificity of SPR is significantly improved. The performance of the new label-enhanced SPR method was demonstrated by two simple model assays: a small molecule assay and a DNA hybridization assay. The small molecule assay was used to demonstrate the sensitivity enhancement of the method, and how competitive assays can be used for relative affinity determination. The DNA assay was used to demonstrate the selectivity of the assay, and the capabilities in eliminating noise from bulk liquid composition variations.

Label-Enhanced Surface Plasmon Resonance: A New Concept for Improved Performance in Optical Biosensor Analysis

Science.gov (United States)

Granqvist, Niko; Hanning, Anders; Eng, Lars; Tuppurainen, Jussi; Viitala, Tapani

2013-01-01

Surface plasmon resonance (SPR) is a well-established optical biosensor technology with many proven applications in the study of molecular interactions as well as in surface and material science. SPR is usually applied in the label-free mode which may be advantageous in cases where the presence of a label may potentially interfere with the studied interactions per se. However, the fundamental challenges of label-free SPR in terms of limited sensitivity and specificity are well known. Here we present a new concept called label-enhanced SPR, which is based on utilizing strongly absorbing dye molecules in combination with the evaluation of the full shape of the SPR curve, whereby the sensitivity as well as the specificity of SPR is significantly improved. The performance of the new label-enhanced SPR method was demonstrated by two simple model assays: a small molecule assay and a DNA hybridization assay. The small molecule assay was used to demonstrate the sensitivity enhancement of the method, and how competitive assays can be used for relative affinity determination. The DNA assay was used to demonstrate the selectivity of the assay, and the capabilities in eliminating noise from bulk liquid composition variations. PMID:24217357

Ecological Reserve: Towards a common understanding for river management in South Africa

CSIR Research Space (South Africa)

Van Wyk, E

2006-07-01

Full Text Available The legal requirement for an Ecological Reserve established in South Africa’s water law is commonly regarded by stakeholders as being in direct competition with the needs of humans. This has resulted in much debate and varying interpretations...

456 Hours to Train the Reserve Component: Analysis of the Impact of Increased Annual Training Requirements on 4th Assault Amphibian Battalion

Science.gov (United States)

2016-12-01

blended learning format” (p. 92). Online training can be used in the following ways: a sole source of learning , supplemental traditional, follow-up to... Learned MCI Marine Corps Institute MCO Marine Corps Order MCR Marine Corps Reserve MCTIMS Marine Corps Training Information Management System MCTL...Reserve SMCR Selected Marine Corps Reserve SNCO Staff Noncommissioned Officer SUL Small Unit Leader TAM Technology Acceptance Model TEEP Training

Tiger Team Assessment of the Naval Petroleum Reserves in California

International Nuclear Information System (INIS)

1991-12-01

This report documents the Tiger Team Assessment of the Naval Petroleum Reserves in California (NPRC) which consists of Naval Petroleum Reserve Number 1 (NPR-1), referred to as the Elk Hills oil field and Naval Petroleum Reserve Number 2 (NPR-2), referred to as the Buena Vista oil field, each located near Bakersfield, California. The Tiger Team Assessment was conducted from November 12 to December 13, 1991, under the auspices of DOE's Office of Special Projects (OSP) under the Assistant Secretary for Environment, Safety and Health (EH). The assessment was comprehensive, encompassing environmental, safety, and health (ES ampersand H), and quality assurance (OA) disciplines; site remediation; facilities management; and waste management operations. Compliance with applicable Federal, State of California, and local regulations; applicable DOE Orders; best management practices; and internal NPRC requirements was assessed. In addition, an evaluation of the adequacy and effectiveness of DOE/NPRC, CUSA, and BPOI management of the ES ampersand H/QA programs was conducted

User's guide for the Uranium Ore Reserve Calculation System (URAD)

International Nuclear Information System (INIS)

1988-12-01

The URAD (Uranium Reserves and Data) system consists of four computer programs designed to facilitate the evaluation of uranium ore reserves analysis and the handling of basic uranium assay data. URAD is designed specifically as a training tool for anyone unfamiliar with the methodology, data requirements, and/or general computer applications in the field of uranium ore reserves analysis. However, it can effectively be used in a 'production' environment involving considerable amounts of data. The resulting programs are written in Microsoft FORTRAN (Version 3.1) and may be run on any IBM-compatible microcomputer under DOS 2.1 (or later). Only a basic working knowledge of DOS 2.1 is needed to maintain the system and run the programs. This guide includes the overview of the URAD system, the review of sample data and a complete description of the file structure and sample type formats of the basic sample data files. Program URDAT explains the initial processing of the primary UDAT files to obtain standard output listings and gamma-log interpretations of radiometric data, and to create intermediate UDAT files which are used by the ore reserves programs - RESUV, ORSAC, and SCOR. Figs and tabs

Development of retrieval, reservation and management system for measuring instruments

International Nuclear Information System (INIS)

Tsuda, Kenzo; Ito, Emi.

1985-08-01

In order to computerize the lending and management of measuring instruments, at first, the specification of the software was examined, but thereafter, the development was begun. The largest aim of the computerization was the automation and labor saving of the lending works of diverse measuring instruments and the automatic management. From user side, it is desirable to know the specification and the state of use and reservation of measuring instruments and to be able to easily make reservation based on the information. Besides, from management side, it is desirable to know the location and the state of use and reservation of measuring instruments, to immediately prepare for lending and returning, and to automate the recording of lending and returning. So as to satisfy those conditions, the automatic reservation and management system for measuring instruments was developed. At the same time, the means to simply input required data such as specification, names of manufacturers and equipment number was developed. The input of data was carried out for three months from October, 1984, and the system was almost completed in December, 1984. The full scale operation was started in Junuary, 1985. (Kako, I.)

Status of fossil fuel reserves

International Nuclear Information System (INIS)

Laherrere, J.

2005-01-01

Reserves represent the sum of past and future productions up to the end of production. In most countries the reserve data of fields are confidential. Therefore, fossil fuel reserves are badly known because the published data are more political than technical and many countries make a confusion between resources and reserves. The cumulated production of fossil fuels represents only between a third and a fifth of the ultimate reserves. The production peak will take place between 2020 and 2050. In the ultimate reserves, which extrapolate the past, the fossil fuels represent three thirds of the overall energy. This document analyses the uncertainties linked with fossil fuel reserves: reliability of published data, modeling of future production, comparison with other energy sources, energy consumption forecasts, reserves/production ratio, exploitation of non-conventional hydrocarbons (tar sands, extra-heavy oils, bituminous shales, coal gas, gas shales, methane in overpressure aquifers, methane hydrates), technology impacts, prices impact, and reserves growth. (J.S.)

Biosphere reserves: Attributes for success.

Science.gov (United States)

Van Cuong, Chu; Dart, Peter; Hockings, Marc

2017-03-01

Biosphere reserves established under the UNESCO Man and the Biosphere Program aim to harmonise biodiversity conservation and sustainable development. Concerns over the extent to which the reserve network was living up to this ideal led to the development of a new strategy in 1995 (the Seville Strategy) to enhance the operation of the network of reserves. An evaluation of effectiveness of management of the biosphere reserve network was called for as part of this strategy. Expert opinion was assembled through a Delphi Process to identify successful and less successful reserves and investigate common factors influencing success or failure. Ninety biosphere reserves including sixty successful and thirty less successful reserves in 42 countries across all five Man and the Biosphere Program regions were identified. Most successful sites are the post-Seville generation while the majority of unsuccessful sites are pre-Seville that are managed as national parks and have not been amended to conform to the characteristics that are meant to define a biosphere reserve. Stakeholder participation and collaboration, governance, finance and resources, management, and awareness and communication are the most influential factors in the success or failure of the biosphere reserves. For success, the biosphere reserve concept needs to be clearly understood and applied through landscape zoning. Designated reserves then need a management system with inclusive good governance, strong participation and collaboration, adequate finance and human resource allocation and stable and responsible management and implementation. All rather obvious but it is difficult to achieve without commitment to the biosphere reserve concept by the governance authorities. Copyright © 2016 Elsevier Ltd. All rights reserved.

78 FR 12746 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2013-02-25

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

78 FR 75552 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2013-12-12

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

78 FR 44942 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2013-07-25

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

78 FR 49738 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2013-08-15

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

77 FR 18243 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2012-03-27

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

78 FR 17648 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2013-03-22

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

78 FR 23241 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2013-04-18

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

77 FR 49442 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2012-08-16

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

77 FR 58364 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2012-09-20

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

77 FR 45345 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2012-07-31

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

77 FR 2714 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2012-01-19

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

78 FR 3890 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2013-01-17

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

78 FR 58292 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2013-09-23

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

77 FR 74836 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2012-12-18

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

A study of the effects of enhanced oil recovery agents on the quality of Strategic Petroleum Reserves crude oil. Final technical report

Energy Technology Data Exchange (ETDEWEB)

Kabadi, V.N.

1992-10-01

The project was initiated on September 1, 1990. The objective of the project was to carry out a literature search to estimate the types and extents of long time interactions of enhanced oil recovery (EOR) agents, such as surfactants, caustics and polymers, with crude oil. This information is necessary to make recommendations about mixing EOR crude oil with crude oils from primary and secondary recovery processes in the Strategic Petroleum Reserve (SPR). Data were sought on both adverse and beneficial effects of EOR agents that would impact handling, transportation and refining of crude oil. An extensive literature search has been completed, and the following informations has been compiled: (1) a listing of existing EOR test and field projects; (2) a listing of currently used EOR agents; and (3) evidence of short and long term physical and chemical interactions of these EOR-agents with hydrocarbons, and their effects on the quality of crude oil at long times. This information is presented in this report. Finally some conclusions are derived and recommendations are made. Although the conclusions are based mostly on extrapolations because of lack of specific data, it is recommended that the enhancement of the rates of biodegradation of oil catalyzed by the EOR agents needs to be further studied. There is no evidence of substantial long term effects on crude oil because of other interactions. Some recommendations are also made regarding the types of studies that would be necessary to determine the effect of certain EOR agents on the rates of biodegradation of crude oil.

Application of ecological criteria in selecting marine reserves and developing reserve networks

Science.gov (United States)

Roberts, Callum M.; Branch, George; Bustamante, Rodrigo H.; Castilla, Juan Carlos; Dugan, Jenifer; Halpern, Benjamin S.; Lafferty, Kevin D.; Leslie, Heather; McArdle, Deborah; Ruckelshaus, Mary; Warner, Robert R.

2003-01-01

Marine reserves are being established worldwide in response to a growing recognition of the conservation crisis that is building in the oceans. However, designation of reserves has been largely opportunistic, or protective measures have been implemented (often overlapping and sometimes in conflict) by different entities seeking to achieve different ends. This has created confusion among both users and enforcers, and the proliferation of different measures provides a false sense of protection where little is offered. This paper sets out a procedure grounded in current understanding of ecological processes, that allows the evaluation and selection of reserve sites in order to develop functional, interconnected networks of fully protected reserves that will fulfill multiple objectives. By fully protected we mean permanently closed to fishing and other resource extraction. We provide a framework that unifies the central aims of conservation and fishery management, while also meeting other human needs such as the provision of ecosystem services (e.g., maintenance of coastal water quality, shoreline protection, and recreational opportunities). In our scheme, candidate sites for reserves are evaluated against 12 criteria focused toward sustaining the biological integrity and productivity of marine systems at both local and regional scales. While a limited number of sites will be indispensable in a network, many will be of similar value as reserves, allowing the design of numerous alternative, biologically adequate networks. Devising multiple network designs will help ensure that ecological functionality is preserved throughout the socioeconomic evaluation process. Too often, socioeconomic criteria have dominated the process of reserve selection, potentially undermining their efficacy. We argue that application of biological criteria must precede and inform socioeconomic evaluation, since maintenance of ecosystem functioning is essential for meeting all of the goals for

Does obesity compromise ovarian reserve markers? A clinician's perspective.

Science.gov (United States)

Malhotra, Neena; Bahadur, Anupama; Singh, Neeta; Kalaivani, Mani; Mittal, Suneeta

2013-01-01

The aim of the study was to ascertain if increasing body mass index (BMI) adversely affects ovarian reserve among infertile women of Asian origin undergoing in vitro fertilization (IVF). This prospective study on 183 women was carried out in the infertility clinic of All India Institute of Medical Sciences, New Delhi, India. Blood hormonal assay in all patients including follicle-stimulating hormone (FSH), luteinizing hormone (LH) and inhibin B was performed on day 2/3 of a spontaneous cycle. A transvaginal ultrasonographic examination on day 2-5 of the menstrual cycle was done for antral follicle count (AFC) and ovarian volume. A correlation between BMI and ovarian reserve parameters like FSH, LH, inhibin B, antral follicle count and ovarian volume was noted. Age was comparable in the three BMI groups. The mean duration of infertility was 8.38 years. Compared to the normal weight, the overweight and obese women had a statistically significantly low inhibin B (p women had a significantly low AFC (p right side. Incorporating anti-mullerian hormone, a newer marker for ovarian reserve, may benefit these obese infertile women. Further work is required to elucidate the mechanisms underlying the effect of obesity on inhibin B as a marker of ovarian reserve in infertile women. The best marker to check the ovarian reserve is perhaps the woman's performance during an IVF cycle. However, considering the psychological and financial stress of the procedure, it may seem wise to consider counseling of obese women on their expected performance in the first cycle of IVF through such studies.

A socio-environmental monitoring system for a UNESCO biosphere reserve.

Science.gov (United States)

Lowell, Kim

2017-11-03

To identify potentially critical changes in an area's ongoing ability to produce multiple ecosystem services, a monitoring system was designed and implemented for the Mornington Peninsula and Westernport Biosphere Reserve in southeast Australia. The system is underpinned by an "environmental vital signs" (EVS) approach that was adopted to provide early warning of critical changes in human and natural characteristics of the area. The six themes monitored are non-coastal water, land including vegetation, biodiversity, natural heritage, built environment (including human population and economic activity), and coasts. These are monitored for the entire area, and each of its five constituent town council areas. After a critical change in any of these is identified, further investigation is required to identify causal factors and, if required, determine an appropriate response. The system relies on data available from external (third-party) organisations to monitor the natural and human characteristics of the area that were important in its designation as a UNESCO biosphere reserve. Strengths and weaknesses associated with the use of third-party data are discussed. These include adoption of baseline years and data reporting periods for different factors, costs, and data quality.

Technical aspects and limitations of fractional flow reserve measurement.

Science.gov (United States)

Jerabek, Stepan; Kovarnik, Tomas

2018-02-27

The only indication for coronary revascularization is elimination of ischaemia. Invasive hemodynamic methods (fractional flow reserve - FFR and instantaneous wave-free ratio (iFR) are superior to coronary angiography in detection of lesions causing myocardial ischaemia. Current European guidelines for myocardial revascularization recommend using of FFR for detection of functional assessment of lesions severity in category IA and number of these procedures increases. However, routine usage of these methods requires knowledge of technical requirements and limitations. The aim of the study is to summarise good clinical practice for FFR and iFR measurements with explanation of possible technical challenges, that are necessary for increasing of measurement accuracy. Authors describe frequent technical mistakes and malpractice during invasive assessment of lesion severity in coronary arteries.

Electron bunch profile reconstruction in the few fs regime using coherent Smith-Purcell radiation

International Nuclear Information System (INIS)

Bartolini, R; Delerue, N; Doucas, G; Reichold, A; Clarke, C

2012-01-01

Advanced accelerators for fourth generation light sources based on high brightness linacs or laser-driven wakefield accelerators will operate with intense, highly relativistic electron bunches that are only a few fs long. Diagnostic techniques for the determination of temporal profile of such bunches are required to be non invasive, single shot, economic and with the required resolution in the fs regime. The use of a radiative process such as coherent Smith-Purcell radiation (SPR), is particularly promising with this respect. In this technique the beam is made to radiate a small amount of electromagnetic radiation and the temporal profile is reconstructed from the measured spectral distribution of the radiation. We summarise the advantages of SPR and present the design parameters and preliminary results of the experiments at the FACET facility at SLAC. We also discuss a new approach to the problem of the recovery of the 'missing phase', which is essential for the accurate reconstruction of the temporal bunch profile.

Sensitive detection of capsaicinoids using a surface plasmon resonance sensor with anti-homovanillic Acid polyclonal antibodies.

Science.gov (United States)

Nakamura, Shingo; Yatabe, Rui; Onodera, Takeshi; Toko, Kiyoshi

2013-11-13

Recently, highly functional biosensors have been developed in preparation for possible large-scale terrorist attacks using chemical warfare agents. Practically applicable sensors are required to have various abilities, such as high portability and operability, the capability of performing rapid and continuous measurement, as well as high sensitivity and selectivity. We developed the detection method of capsaicinoids, the main component of some lachrymators, using a surface plasmon resonance (SPR) immunosensor as an on-site detection sensor. Homovanillic acid, which has a vanillyl group similar to capsaicinoids such as capsaicin and dihydrocapsaicin, was bound to Concholepas concholepas hemocyanin (CCH) for use as an immunogen to generate polyclonal antibodies. An indirect competitive assay was carried out to detect capsaicinoids using SPR sensor chips on which different capsaicin analogues were immobilized. For the sensor chip on which 4-hydroxy-3-methoxybenzylamine hydrochloride was immobilized, a detection limit of 150 ppb was achieved. We found that the incubation time was not required and the detection can be completed in five minutes.

Electron Bunch Profile Reconstruction in the Few fs Regime using Coherent Smith-Purcell Radiation

International Nuclear Information System (INIS)

Bartolini, R.; Clarke, C.; Delerue, N.; Doucasa, G.; Reicholda, A.

2012-01-01

Advanced accelerators for fourth generation light sources based on high brightness linacs or laser-driven wakefield accelerators will operate with intense, highly relativistic electron bunches that are only a few fs long. Diagnostic techniques for the determination of temporal profile of such bunches are required to be non invasive, single shot, economic and with the required resolution in the fs regime. The use of a radiative process such as coherent Smith-Purcell radiation (SPR), is particularly promising with this respect. In this technique the beam is made to radiate a small amount of electromagnetic radiation and the temporal profile is reconstructed from the measured spectral distribution of the radiation. We summarise the advantages of SPR and present the design parameters and preliminary results of the experiments at the FACET facility at SLAC. We also discuss a new approach to the problem of the recovery of the 'missing phase', which is essential for the accurate reconstruction of the temporal bunch profile.

Fossil Energy Program annual progress report for April 1997 through March 1998

Energy Technology Data Exchange (ETDEWEB)

Judkins, R.R.

1998-07-01

This report covers progress made on research and development projects that contribute to the advancement of fossil energy technologies, covering the areas of coal, clean coal technology, gas, petroleum, and support to the Strategic Petroleum Reserve (SPR). Papers are arranged under the following topical sections: materials research and development; environmental analysis support; bioprocessing research; fossil fuels supplies modeling and research; and oil and gas production.

78 FR 30911 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

Science.gov (United States)

2013-05-23

...This notice announces a meeting of the Environmental Management Site-Specific Advisory Board (EM SSAB), Oak Ridge Reservation. The Federal Advisory Committee Act (Pub. L. No. 92-463, 86 Stat. 770) requires that public notice of this meeting be announced in the Federal Register.

Autolytic Activity and Plasma Binding Study of Aap, a Novel Minor Autolysin of Streptococcus pneumoniae

Directory of Open Access Journals (Sweden)

Ramina Mahboobi

2016-04-01

Full Text Available Pneumococcal autolysins are enzymes involved in cell wall turnover and cellular division physiologically. They have been found to be involved in the pneumococcus pathogenesis. The aim of this study was to identify the autolytic activity of Spr1754 as a novel protein of Streptococcus pneumoniae. Moreover, the binding of the recombinant protein to plasma proteins was also determined. The spr1754 gene was amplified by PCR and cloned into the pET21a(+ prokaryotic expression vector. The constructed pET21a(+/spr1754 recombinant plasmid was transformed into E. coli Origami (DE3 and induced using IPTG. The recombinant protein of Spr1754 was purified by Ni-NTA affinity chromatography and confirmed by SDS-PAGE and Western blot analysis using anti-His tag monoclonal antibody. Autolytic activity and the ability of the recombinant protein in binding to plasma proteins were performed using zymogram analysis and western blot, respectively. The spr1754 with expected size was cloned and overexpressed in Escherichia coli Origami (DE3, successfully. After purification of the Spr1754 recombinant protein, the autolytic activity was observed by zymography. Of the four plasma proteins used in this study, binding of lactoferrin to Spr1754 recombinant protein was shown. The Spr1754 recombinant protein has a bifunctional activity, i.e., as being autolysin and lactoferrin binding and designated as Aap (autolytic/ adhesion/ pneumococcus. Nevertheless, characterization of the Aap needs to be followed using gene inactivation and cell wall localization.

Design and analysis of the Collider SPXA/SPRA spool piece vacuum barrier

International Nuclear Information System (INIS)

Cruse, G.; Aksel, G.

1993-04-01

A design for the Collider SPXA/SPRA spool piece vacuum barrier was developed to meet a variety of thermal and structural performance requirements. Both composite and stainless steel alternatives were investigated using detailed finite-element analysis before selecting an optimized version of the ASST SPR spool vacuum barrier design. This design meets the structural requirements and will be able to meet the thermal performance requirements by using some newer thermal strapping configurations

War Reserve Analysis and Secondary Item Procureability Assessment of the AMCOM Supported Weapon Systems

National Research Council Canada - National Science Library

Maddux, Gary

2000-01-01

.... IOD evaluates the impacts of nonavailability of secondary items on the life cycle supportability of AMCOM weapon systems and evaluates the producibility of secondary items for war reserve requirements...

Scatter radiation in digital tomosynthesis of the breast

International Nuclear Information System (INIS)

Sechopoulos, Ioannis; Suryanarayanan, Sankararaman; Vedantham, Srinivasan; D'Orsi, Carl J.; Karellas, Andrew

2007-01-01

Digital tomosynthesis of the breast is being investigated as one possible solution to the problem of tissue superposition present in planar mammography. This imaging technique presents various advantages that would make it a feasible replacement for planar mammography, among them similar, if not lower, radiation glandular dose to the breast; implementation on conventional digital mammography technology via relatively simple modifications; and fast acquisition time. One significant problem that tomosynthesis of the breast must overcome, however, is the reduction of x-ray scatter inclusion in the projection images. In tomosynthesis, due to the projection geometry and radiation dose considerations, the use of an antiscatter grid presents several challenges. Therefore, the use of postacquisition software-based scatter reduction algorithms seems well justified, requiring a comprehensive evaluation of x-ray scatter content in the tomosynthesis projections. This study aims to gain insight into the behavior of x-ray scatter in tomosynthesis by characterizing the scatter point spread functions (PSFs) and the scatter to primary ratio (SPR) maps found in tomosynthesis of the breast. This characterization was performed using Monte Carlo simulations, based on the Geant4 toolkit, that simulate the conditions present in a digital tomosynthesis system, including the simulation of the compressed breast in both the cranio-caudal (CC) and the medio-lateral oblique (MLO) views. The variation of the scatter PSF with varying tomosynthesis projection angle, as well as the effects of varying breast glandular fraction and x-ray spectrum, was analyzed. The behavior of the SPR for different projection angle, breast size, thickness, glandular fraction, and x-ray spectrum was also analyzed, and computer fit equations for the magnitude of the SPR at the center of mass for both the CC and the MLO views were found. Within mammographic energies, the x-ray spectrum was found to have no appreciable

Mapping Forest Inventory and Analysis forest land use: timberland, reserved forest land, and other forest land

Science.gov (United States)

Mark D. Nelson; John Vissage

2007-01-01

The Forest Inventory and Analysis (FIA) program produces area estimates of forest land use within three subcategories: timberland, reserved forest land, and other forest land. Mapping these subcategories of forest land requires the ability to spatially distinguish productive from unproductive land, and reserved from nonreserved land. FIA field data were spatially...

Recent revisions of phosphate rock reserves and resources: a critique

Science.gov (United States)

Edixhoven, J. D.; Gupta, J.; Savenije, H. H. G.

2014-12-01

Phosphate rock (PR) is a finite mineral indispensable for fertilizer production, while P (phosphorus) is a major pollutant if applied or discharged in excess, causing widespread eutrophication (Carpenter and Bennet, 2011). High-grade PR is obtained from deposits which took millions of years to form and which are gradually being depleted. Recently, global PR reserves as reported by the US Geological Survey (USGS) have increased from 16 000 Mt PR in 2010 to 65 000 Mt PR in 2011 and further to 67 000 Mt PR in 2014. The majority of this 4-fold increase is based on a 2010 report by the International Fertilizer Development Center (IFDC), which increased Moroccan reserves from 5700 Mt PR as reported by USGS, to 51 000 Mt PR, reported as upgraded ("beneficiated") concentrate. The report also increased global resources from 163 000 Mt PR reported in the literature in 1989 to 290 000 Mt PR. IFDC used a simplified resource terminology which does not use the underlying thresholds for reserves and resources used in the USGS classification. IFDC proposed that agreement should be reached on PR resource terminology which should be as simple as possible. The report has profoundly influenced the PR scarcity debate, shifting the emphasis from resource scarcity to the pollution angle of the phosphate problem. In view of the high dependence of food production on PR and the importance of data on PR reserves and resources for scientific analysis and policy making, data on PR deposits should be transparent, comparable, reliable, and credible. We analyze (i) how IFDC's simplified terminology compares to international best practice in resource classification and whether it is likely to yield data that meet these requirements, (ii) whether the difference in volume between raw PR ore and upgraded PR concentrate is sufficiently noted in the literature, and (iii) whether the IFDC report presents an accurate picture of PR reserves and resources. We conclude that, while there is a global

Surface Plasmon Resonance based sensing of lysozyme in serum on Micrococcus lysodeikticus-modified graphene oxide surfaces.

Science.gov (United States)

Vasilescu, Alina; Gáspár, Szilveszter; Gheorghiu, Mihaela; David, Sorin; Dinca, Valentina; Peteu, Serban; Wang, Qian; Li, Musen; Boukherroub, Rabah; Szunerits, Sabine

2017-03-15

Lysozyme is an enzyme found in biological fluids, which is upregulated in leukemia, renal diseases as well as in a number of inflammatory gastrointestinal diseases. We present here the development of a novel lysozyme sensing concept based on the use of Micrococcus lysodeikticus whole cells adsorbed on graphene oxide (GO)-coated Surface Plasmon Resonance (SPR) interfaces. M. lysodeikticus is a typical enzymatic substrate for lysozyme. Unlike previously reported sensors which are based on the detection of lysozyme through bioaffinity interactions, the bioactivity of lysozyme will be used here for sensing purposes. Upon exposure to lysozyme containing serum, the integrity of the bacterial cell wall is affected and the cells detach from the GO based interfaces, causing a characteristic decrease in the SPR signal. This allows sensing the presence of clinically relevant concentrations of lysozyme in undiluted serum samples. Copyright © 2016 Elsevier B.V. All rights reserved.

Fossil Energy Program Annual Progress Report for the Period April 1, 2000 through March 31, 2001

Energy Technology Data Exchange (ETDEWEB)

Judkins, RR

2001-06-14

This report covers progress made at Oak Ridge National Laboratory (ORNL) on research and development projects that contribute to the advancement of fossil energy technologies. Projects on the ORNL Fossil Energy Program are supported by the U.S. Department of Energy (DOE) Office of Fossil Energy, the DOE National Energy Technology Laboratory (NETL), the DOE Fossil Energy Clean Coal Technology (CCT) Program, the DOE National Petroleum Technology Office, and the DOE Fossil Energy Office of Strategic Petroleum Reserve (SPR). The ORNL Fossil Energy Program research and development activities cover the areas of coal, clean coal technology, gas, petroleum, and support to the SPR. An important part of the Fossil Energy Program is technical management of all activities on the DOE Fossil Energy Advanced Research (AR) Materials Program. The AR Materials Program involves research at other DOE and government laboratories, at universities, and at industrial organizations.

Disaggregating reserve-to-production ratios: An algorithm for United States oil and gas reserve development

Science.gov (United States)

Williams, Charles William

Reserve-to-production ratios for oil and gas development are utilized by oil and gas producing states to monitor oil and gas reserve and production dynamics. These ratios are used to determine production levels for the manipulation of oil and gas prices while maintaining adequate reserves for future development. These aggregate reserve-to-production ratios do not provide information concerning development cost and the best time necessary to develop newly discovered reserves. Oil and gas reserves are a semi-finished inventory because development of the reserves must take place in order to implement production. These reserves are considered semi-finished in that they are not counted unless it is economically profitable to produce them. The development of these reserves is encouraged by profit maximization economic variables which must consider the legal, political, and geological aspects of a project. This development is comprised of a myriad of incremental operational decisions, each of which influences profit maximization. The primary purpose of this study was to provide a model for characterizing a single product multi-period inventory/production optimization problem from an unconstrained quantity of raw material which was produced and stored as inventory reserve. This optimization was determined by evaluating dynamic changes in new additions to reserves and the subsequent depletion of these reserves with the maximization of production. A secondary purpose was to determine an equation for exponential depletion of proved reserves which presented a more comprehensive representation of reserve-to-production ratio values than an inadequate and frequently used aggregate historical method. The final purpose of this study was to determine the most accurate delay time for a proved reserve to achieve maximum production. This calculated time provided a measure of the discounted cost and calculation of net present value for developing new reserves. This study concluded that