WorldWideScience

Sample records for research update number

  1. Research reactor fuel - an update

    International Nuclear Information System (INIS)

    Finlay, M.R.; Ripley, M.I.

    2003-01-01

    In the two years since the last ANA conference there have been marked changes in the research reactor fuel scene. A new low-enriched uranium (LEU) fuel, 'monolithic' uranium molybdenum, has shown such promise in initial trials that it may be suitable to meet the objectives of the Joint Declaration signed by Presidents Bush and Putin to commit to converting all US and Russian research reactors to LEU by 2012. Development of more conventional aluminium dispersion UMo LEU fuel has continued in the meantime and is entering the final qualification stage of multiple full sized element irradiations. Despite this progress, the original 2005 timetable for UMo fuel qualification has slipped and research reactors, including the RRR, may not convert from silicide to UMo fuel before 2007. The operators of the Swedish R2 reactor have been forced to pursue the direct route of qualifying a UMo lead test assembly (LTA) in order to meet spent fuel disposal requirements of the Swedish law. The LTA has recently been fabricated and is expected to be loaded shortly into the R2 reactor. We present an update of our previous ANA paper and details of the qualification process for UMo fuel

  2. UPDATE: Applications of Research in Music Education. UPDATE Yearbook

    Science.gov (United States)

    Rowman & Littlefield Education, 2005

    2005-01-01

    The Fall 2004 and Spring 2005 issues of "UPDATE: Applications of Research in Music Education," in one print volume, presents hard facts and statistical data in a style that can be easily understood and appreciated by music researchers, teachers, graduates, and undergraduates alike. Includes advice to first-year music teachers, instrument…

  3. Stuttering: Clinical and research update.

    Science.gov (United States)

    Perez, Hector R; Stoeckle, James H

    2016-06-01

    To provide an update on the epidemiology, genetics, pathophysiology, diagnosis, and treatment of developmental stuttering. The MEDLINE and Cochrane databases were searched for past and recent studies on the epidemiology, genetics, pathophysiology, diagnosis, and treatment of developmental stuttering. Most recommendations are based on small studies, limited-quality evidence, or consensus. Stuttering is a speech disorder, common in persons of all ages, that affects normal fluency and time patterning of speech. Stuttering has been associated with differences in brain anatomy, functioning, and dopamine regulation thought to be due to genetic causes. Attention to making a correct diagnosis or referral in children is important because there is growing consensus that early intervention with speech therapy for children who stutter is critical. For adults, stuttering can be associated with substantial psychosocial morbidity including social anxiety and low quality of life. Pharmacologic treatment has received attention in recent years, but clinical evidence is limited. The mainstay of treatment for children and adults remains speech therapy. A growing body of research has attempted to uncover the pathophysiology of stuttering. Referral for speech therapy remains the best option for children and adults. Copyright© the College of Family Physicians of Canada.

  4. RESEARCH BULLETIN. NUMBER 2.

    Science.gov (United States)

    American Foundation for the Blind, New York, NY.

    THE FOLLOWING REPORTS CONCERNING RESEARCH WITH THE VISUALLY HANDICAPPED ARE CONTAINED IN THIS BULLETIN--"SELECTED IMPAIRMENTS BY ETIOLOGY AND ACTIVITY LIMITATION, UNITED STATES, JULY 1959-JUNE 1961,""AN EXPERIMENT USING REVISED STIMULUS PRESENTATION" BY S. KARP, "EXPERIMENTS IN TACTUAL PERCEPTION" BY S. KARP, "A STUDY OF BRAILLE CODE REVISIONS" BY…

  5. Argo packing friction research update

    International Nuclear Information System (INIS)

    VanTassell, D.M.

    1994-01-01

    This paper focuses on the issue of valve packing friction and its affect on the operability of motor- and air-operated valves (MOVs and AOVs). At this time, most nuclear power plants are required to perform postmaintenance testing following a packing adjustment or replacement. In many cases, the friction generated by the packing does not impact the operability window of a valve. However, to date there has not been a concerted effort to substantiate this claim. To quantify the effects of packing friction, it has become necessary to develop a formula to predict the friction effects accurately. This formula provides a much more accurate method of predicting packing friction than previously used factors based strictly on stem diameter. Over the past 5 years, Argo Packing Company has been developing and testing improved graphite packing systems at research facilities, such as AECL Chalk River and Wyle Laboratories. Much of this testing has centered around reducing and predicting friction that is related to packing. In addition, diagnostic testing for Generic Letter 89-10 MOVs and AOVs has created a significant data base. In July 1992 Argo asked several utilities to provide running load data that could be used to quantify packing friction repeatability and predictability. This technical paper provides the basis to predict packing friction, which will improve calculations for thrust requirements for Generic Leter 89-10 and future AOV programs. In addition, having an accurate packing friction formula will improve packing performance when low running loads are identified that would indicate insufficient sealing force

  6. 78 FR 26244 - Updating of Employer Identification Numbers

    Science.gov (United States)

    2013-05-06

    ... combat schemes that abuse the tax system through the use of nominees, which results in the concealing of... consideration during future updates of those items. Three of the comments did not support the rule in the...

  7. Severe Accident Research Program plan update

    International Nuclear Information System (INIS)

    1992-12-01

    In August 1989, the staff published NUREG-1365, ''Revised Severe Accident Research Program Plan.'' Since 1989, significant progress has been made in severe accident research to warrant an update to NUREG-1365. The staff has prepared this SARP Plan Update to: (1) Identify those issues that have been closed or are near completion, (2) Describe the progress in our understanding of important severe accident phenomena, (3) Define the long-term research that is directed at improving our understanding of severe accident phenomena and developing improved methods for assessing core melt progression, direct containment heating, and fuel-coolant interactions, and (4) Reflect the growing emphasis in two additional areas--advanced light water reactors, and support for the assessment of criteria for containment performance during severe accidents. The report describes recent major accomplishments in understanding the underlying phenomena that can occur during a severe accident. These include Mark I liner failure, severe accident scaling methodology, source term issues, core-concrete interactions, hydrogen transport and combustion, TMI-2 Vessel Investigation Project, and direct containment heating. The report also describes the major planned activities under the SARP over the next several years. These activities will focus on two phenomenological issues (core melt progression, and fuel-coolant interactions and debris coolability) that have significant uncertainties that impact our understanding and ability to predict severe accident phenomena and their effect on containment performance SARP will also focus on severe accident code development, assessment and validation. As the staff completes the research on severe accident issues that relate to current generation reactors, continued research will focus on efforts to independently evaluate the capability of new advanced light water reactor designs to withstand severe accidents

  8. Federal Geothermal Research Program Update, FY 2000

    Energy Technology Data Exchange (ETDEWEB)

    Renner, Joel Lawrence

    2001-08-01

    The Department of Energy's Geothermal Program serves two broad purposes: 1) to assist industry in overcoming near-term barriers by conducting cost-shared research and field verification that allows geothermal energy to compete in today's aggressive energy markets; and 2) to undertake fundamental research with potentially large economic payoffs. The four categories of work used to distinguish the research activities of the Geothermal Program during FY 2000 reflect the main components of real-world geothermal projects. These categories form the main sections of the project descriptions in this Research Update. Exploration Technology research focuses on developing instruments and techniques to discover hidden hydrothermal systems and to explore the deep portions of known systems. Research in geophysical and geochemical methods is expected to yield increased knowledge of hidden geothermal systems. Reservoir Technology research combines laboratory and analytical investigations with equipment development and field testing to establish practical tools for resource development and management for both hydrothermal reservoirs and enhanced geothermal systems. Research in various reservoir analysis techniques is generating a wide range of information that facilitates development of improved reservoir management tools. Drilling Technology focuses on developing improved, economic drilling and completion technology for geothermal wells. Ongoing research to avert lost circulation episodes in geothermal drilling is yielding positive results. Conversion Technology research focuses on reducing costs and improving binary conversion cycle efficiency, to permit greater use of the more abundant moderate-temperature geothermal resource, and on the development of materials that will improve the operating characteristics of many types of geothermal energy equipment. Increased output and improved performance of binary cycles will result from investigations in heat cycle research.

  9. Research and optimization of page updated forecast on Nutch

    Directory of Open Access Journals (Sweden)

    HU Wei

    2016-08-01

    Full Text Available Web page updated prediction method of Nutch is an adjacent method and its relevant update parameters need to be set artificially,not adaptively adjustable,and unable to cope with the differences of massive web page updates.To address this problem,this paper puts forward dynamic selection strategy to improve the method of Nutch web page updated prediction.When the historical updated web page data are insufficient,the strategy uses DBSCAN clustering algorithm based on MapReduce to reduce the number of the pages of the crawler system crawling,the update cycle of the sample web pages is used as update cycle of other pages which are in the same category.When the historical updated web page data are enough,the data are used to model with the Poisson Process,which can more accurately predict each web page update cycle.Finally the improving strategy is tested in the Hadoop distributed platform.The experimental results show that the performance of optimized web page updated prediction method is better.

  10. Federal Geothermal Research Program Update Fiscal Year 2003

    Energy Technology Data Exchange (ETDEWEB)

    2004-03-01

    The Department of Energy (DOE) and its predecessors have conducted research and development (R&D) in geothermal energy since 1971. To develop the technology needed to harness the Nation's vast geothermal resources, DOE's Office of Geothermal Technologies oversees a network of national laboratories, industrial contractors, universities, and their subcontractors. The following mission and goal statements guide the overall activities of the Office. The goals are: (1) Reduce the levelized cost of generating geothermal power to 3-5 cents per kWh by 2007; (2) Double the number of States with geothermal electric power facilities to eight by 2006; and (3) Supply the electrical power or heat energy needs of 7 million homes and businesses in the United States by 2010. This Federal Geothermal Program Research Update reviews the accomplishments of DOE's Geothermal Program for Federal Fiscal Year (FY) 2003. The information contained in this Research Update illustrates how the mission and goals of the Office of Geothermal Technologies are reflected in each R&D activity. The Geothermal Program, from its guiding principles to the most detailed research activities, is focused on expanding the use of geothermal energy. balanced strategy for the Geothermal Program.

  11. Federal Geothermal Research Program Update Fiscal Year 2002

    Energy Technology Data Exchange (ETDEWEB)

    2003-09-01

    The Department of Energy (DOE) and its predecessors have conducted research and development (R&D) in geothermal energy since 1971. To develop the technology needed to harness the Nation's vast geothermal resources, DOE's Office of Geothermal Technologies oversees a network of national laboratories, industrial contractors, universities, and their subcontractors. The goals are: (1) Double the number of States with geothermal electric power facilities to eight by 2006; (2) Reduce the levelized cost of generating geothermal power to 3-5 cents per kWh by 2007; and (3) Supply the electrical power or heat energy needs of 7 million homes and businesses in the United States by 2010. This Federal Geothermal Program Research Update reviews the specific objectives, status, and accomplishments of DOE's Geothermal Program for Federal Fiscal Year (FY) 2002. The information contained in this Research Update illustrates how the mission and goals of the Office of Geothermal Technologies are reflected in each R&D activity. The Geothermal Program, from its guiding principles to the most detailed research activities, is focused on expanding the use of geothermal energy. balanced strategy for the Geothermal Program.

  12. Updating the list of chromosome numbers for Philodendron (Araceae)

    OpenAIRE

    Vasconcelos, Emanuelle V.; Brasileiro-Vidal, Ana C.; Benko-Iseppon, Ana M.; Vasconcelos, Santelmo

    2017-01-01

    ABSTRACT Aiming for a better understanding of karyotype evolution within Philodendron, we report chromosome counts for 23 species of the genus, of which 19 are being reported for the first time, thus increasing to 84 ( ca. 17 % of the genus) the total number of species with available chromosome counts. The diploid numbers 2 n = 32 and 2 n = 34 were the most common, with 10 and 11 species, respectively, whereas only two species presented different chromosome numbers ( P. giganteum with 2 n = 3...

  13. Extremes in Otolaryngology Resident Surgical Case Numbers: An Update.

    Science.gov (United States)

    Baugh, Tiffany P; Franzese, Christine B

    2017-06-01

    Objectives The purpose of this study is to examine the effect of minimum case numbers on otolaryngology resident case log data and understand differences in minimum, mean, and maximum among certain procedures as a follow-up to a prior study. Study Design Cross-sectional survey using a national database. Setting Academic otolaryngology residency programs. Subjects and Methods Review of otolaryngology resident national data reports from the Accreditation Council for Graduate Medical Education (ACGME) resident case log system performed from 2004 to 2015. Minimum, mean, standard deviation, and maximum values for total number of supervisor and resident surgeon cases and for specific surgical procedures were compared. Results The mean total number of resident surgeon cases for residents graduating from 2011 to 2015 ranged from 1833.3 ± 484 in 2011 to 2072.3 ± 548 in 2014. The minimum total number of cases ranged from 826 in 2014 to 1004 in 2015. The maximum total number of cases increased from 3545 in 2011 to 4580 in 2015. Multiple key indicator procedures had less than the required minimum reported in 2015. Conclusion Despite the ACGME instituting required minimum numbers for key indicator procedures, residents have graduated without meeting these minimums. Furthermore, there continues to be large variations in the minimum, mean, and maximum numbers for many procedures. Variation among resident case numbers is likely multifactorial. Ensuring proper instruction on coding and case role as well as emphasizing frequent logging by residents will ensure programs have the most accurate data to evaluate their case volume.

  14. Updating the list of chromosome numbers for Philodendron (Araceae

    Directory of Open Access Journals (Sweden)

    Emanuelle V. Vasconcelos

    Full Text Available ABSTRACT Aiming for a better understanding of karyotype evolution within Philodendron, we report chromosome counts for 23 species of the genus, of which 19 are being reported for the first time, thus increasing to 84 ( ca. 17 % of the genus the total number of species with available chromosome counts. The diploid numbers 2 n = 32 and 2 n = 34 were the most common, with 10 and 11 species, respectively, whereas only two species presented different chromosome numbers ( P. giganteum with 2 n = 30 and P. adamantinum with 2 n = 36. The results are discussed in the context of previous analyses of karyotypes of Philodendron spp., taking into account bidirectional dysploidy as the main mechanism of chromosome number evolution within the genus.

  15. Federal Geothermal Research Program Update - Fiscal Year 2001

    Energy Technology Data Exchange (ETDEWEB)

    Laney, P.T.

    2002-08-31

    This Federal Geothermal Program Research Update reviews the specific objectives, status, and accomplishments of DOE's Geothermal Program for Federal Fiscal Year (FY) 2001. The information contained in this Research Update illustrates how the mission and goals of the Office of Geothermal Technologies are reflected in each R&D activity. The Geothermal Program, from its guiding principles to the most detailed research activities, is focused on expanding the use of geothermal energy.

  16. Using Random Numbers in Science Research Activities.

    Science.gov (United States)

    Schlenker, Richard M.; And Others

    1996-01-01

    Discusses the importance of science process skills and describes ways to select sets of random numbers for selection of subjects for a research study in an unbiased manner. Presents an activity appropriate for grades 5-12. (JRH)

  17. USMARC update on swine reproduction research

    Science.gov (United States)

    Swine research at USMARC has continued to focus on meat quality, improvement of genomic resources and reproduction, specifically estrus traits, sow longevity and lifetime productivity. This report will focus on research in behavioral anestrus in gilts. Gilts that reach puberty at an earlier age are ...

  18. Transcutaneous Electrical Nerve Stimulation: Research Update.

    Science.gov (United States)

    Johns, Florene Carnicelli

    Currently, research is being performed in the area of nonsurgical and nonchemical means for influencing the body's threshold for pain. Today, transcutaneous electrical nerve stimulation (TENS) is being widely used for this purpose. Application of this treatment can be confusing, however, because determining such things as selection of the proper…

  19. Early Brain Development Research Review and Update

    Science.gov (United States)

    Schiller, Pam

    2010-01-01

    Thanks to imaging technology used in neurobiology, people have access to useful and critical information regarding the development of the human brain. This information allows them to become much more effective in helping children in their early development. In fact, when people base their practices on the findings from medical science research,…

  20. Leisure and the Elderly. Research Update.

    Science.gov (United States)

    Siegenthaler, K. L.

    1996-01-01

    Research shows a relationship between older adults' leisure involvement and life satisfaction. Individuals who participate more frequently and in a greater variety of activities experience greater psychological well-being. The paper discusses successful aging and leisure participation, provides current definitions, and examines perceptions of…

  1. Pediatric headache: update on recent research.

    Science.gov (United States)

    Hershey, Andrew D

    2012-02-01

    Primary headache are one of the most common health complaints in children and adolescents, yet there remain significant gaps in our understanding of the underlying pathophysiology of these conditions. Recently, there have been several areas of research that have assisted with filling this gap in our knowledge. These areas include a better understanding of the disease characteristics including additional associated symptoms and the refinement of the description of related conditions and comorbidities; continued examination of the epidemiology of primary headaches; the progression of migraine across these developmental ages; the molecular and physiological changes; and the potential role for vitamins and cofactor deficiencies in the pathophysiology. These studies continue to add to our fund of knowledge on the basis of migraine and tension-type headache as primary neurological conditions and their impact on the developing brain. © 2012 American Headache Society.

  2. Attachment and eating disorders: a research update.

    Science.gov (United States)

    Tasca, Giorgio A

    2018-03-16

    Prominent models of eating disorders tend to focus on cognitive and behavioral features, but tend not to consider important developmental issues related to affect regulation, interpersonal style, self concept, and mentalization-all of which are well conceptualized within attachment theory. Higher levels of attachment insecurity across diagnoses are related to greater eating disorder symptoms. Low parental care and early trauma may lead to attachment insecurity that then might lead to greater eating disorder symptoms. The association between insecure attachment and eating disorder severity is likely mediated by affect dysregulation and perfectionism. Recent research using the Adult Attachment Interview highlights the importance of reflective functioning in predicting treatment response and therapeutic processes, and on the utility of therapies that increase mentalization. Copyright © 2018 Elsevier Ltd. All rights reserved.

  3. Federal Geothermal Research Program Update Fiscal Year 1999

    Energy Technology Data Exchange (ETDEWEB)

    2004-02-01

    The Department of Energy (DOE) and its predecessors have conducted research and development (R&D) in geothermal energy since 1971. To develop the technology needed to harness the Nation's vast geothermal resources, DOE's Office of Geothermal and Wind Technologies oversees a network of national laboratories, industrial contractors, universities, and their subcontractors. The following mission and goal statements guide the overall activities of the Office of Geothermal and Wind Technologies. This Federal Geothermal Program Research Update reviews the specific objectives, status, and accomplishments of DOE's Geothermal Program for Federal Fiscal Year (FY) 1999. The information contained in this Research Update illustrates how the mission and goals of the Office of Geothermal and Wind Technologies are reflected in each R&D activity. The Geothermal Program, from its guiding principles to the most detailed research activities, is focused on expanding the use of geothermal energy.

  4. Update on the Health Services Research Doctoral Core Competencies.

    Science.gov (United States)

    Burgess, James F; Menachemi, Nir; Maciejewski, Matthew L

    2018-03-13

    To present revised core competencies for doctoral programs in health services research (HSR), modalities to deliver these competencies, and suggested methods for assessing mastery of these competencies. Core competencies were originally developed in 2005, updated (but unpublished) in 2008, modestly updated for a 2016 HSR workforce conference, and revised based on feedback from attendees. Additional feedback was obtained from doctoral program directors, employer/workforce experts and attendees of presentation on these competencies at the AcademyHealth's June 2017 Annual Research Meeting. The current version (V2.1) competencies include the ethical conduct of research, conceptual models, development of research questions, study designs, data measurement and collection methods, statistical methods for analyzing data, professional collaboration, and knowledge dissemination. These competencies represent a core that defines what HSR researchers should master in order to address the complexities of microsystem to macro-system research that HSR entails. There are opportunities to conduct formal evaluation of newer delivery modalities (e.g., flipped classrooms) and to integrate new Learning Health System Researcher Core Competencies, developed by AHRQ, into the HSR core competencies. Core competencies in HSR are a continually evolving work in progress because new research questions arise, new methods are developed, and the trans-disciplinary nature of the field leads to new multidisciplinary and team building needs. © Health Research and Educational Trust.

  5. Research Update on Extreme-Mass-Ratio Inspirals

    International Nuclear Information System (INIS)

    Amaro-Seoane, Pau; Gair, Jonathan R; Pound, Adam; Hughes, Scott A; Sopuerta, Carlos F

    2015-01-01

    The inspirals of stellar-mass mass compact objects into massive black holes in the centres of galaxies are one of the most important sources of gravitational radiation for space- based detectors like LISA or eLISA. These extreme-mass-ratio inspirals (EMRIs) will enable an ambitious research program with implications for astrophysics, cosmology, and fundamental physics. This article is a summary of the talks delivered at the plenary session on EMRIs at the 10th International LISA Symposium. It contains research updates on the following topics: astrophysics of EMRIs; EMRI science potential; and EMRI modeling. (paper)

  6. A research update for southeast poultry research laboratory

    Science.gov (United States)

    The Southeast Poultry Research Laboratory continues with their modernization plan. The 35% architectural drawings have been completed and the project is currently out for bid for the completion of the design and building of the new facility. Research activities in the Exotic and Emerging Avian Vir...

  7. The 2016 database issue of Nucleic Acids Research and an updated molecular biology database collection

    Science.gov (United States)

    Rigden, Daniel J.; Fernández-Suárez, Xosé M.; Galperin, Michael Y.

    2016-01-01

    The 2016 Database Issue of Nucleic Acids Research starts with overviews of the resources provided by three major bioinformatics centers, the U.S. National Center for Biotechnology Information (NCBI), the European Bioinformatics Institute (EMBL-EBI) and Swiss Institute for Bioinformatics (SIB). Also included are descriptions of 62 new databases and updates on 95 databases that have been previously featured in NAR plus 17 previously described elsewhere. A number of papers in this issue deal with resources on nucleic acids, including various kinds of non-coding RNAs and their interactions, molecular dynamics simulations of nucleic acid structure, and two databases of super-enhancers. The protein database section features important updates on the EBI's Pfam, PDBe and PRIDE databases, as well as a variety of resources on pathways, metabolomics and metabolic modeling. This issue also includes updates on popular metagenomics resources, such as MG-RAST, EBI Metagenomics, and probeBASE, as well as a newly compiled Human Pan-Microbe Communities database. A significant fraction of the new and updated databases are dedicated to the genetic basis of disease, primarily cancer, and various aspects of drug research, including resources for patented drugs, their side effects, withdrawn drugs, and potential drug targets. A further six papers present updated databases of various antimicrobial and anticancer peptides. The entire Database Issue is freely available online on the Nucleic Acids Research website (http://nar.oxfordjournals.org/). The NAR online Molecular Biology Database Collection, http://www.oxfordjournals.org/nar/database/c/, has been updated with the addition of 88 new resources and removal of 23 obsolete websites, which brought the current listing to 1685 databases. PMID:26740669

  8. Research Update: Nanoscale electrochemical transistors in correlated oxides

    Directory of Open Access Journals (Sweden)

    Teruo Kanki

    2017-04-01

    Full Text Available Large reversible changes of the electronic transport properties of solid-state oxide materials induced by electrochemical fields have received much attention as a new research avenue in iontronics. In this research update, dramatic transport changes in vanadium dioxide (VO2 nanowires were demonstrated by electric field-induced hydrogenation at room temperature through the nanogaps separated by humid air in a field-effect transistor structure with planar-type gates. This unique structure allowed us to investigate hydrogen intercalation and diffusion behavior in VO2 channels with respect to both time and space. Our results will contribute to further strategic researches to examine fundamental chemical and physical properties of devices and develop iontronic applications, as well as offering new directions to explore emerging functions for sensing, energy, and neuromorphologic devices combining ionic and electronic behaviors in solid-state materials.

  9. Selective mutism: an update and suggestions for future research.

    Science.gov (United States)

    Scott, Samantha; Beidel, Deborah C

    2011-08-01

    Speculation continues regarding the accurate classification of selective mutism and potential etiologic factors. Current research has shed some light on several factors that may predispose some children to this disorder, but conclusions are difficult to draw due to reliance on subjective measures, few comparison groups, and/or limited theoretical grounding. This article provides an update on recent efforts to elucidate the etiologic pathways of selective mutism and on the current debate regarding its strong overlap with anxiety disorders, most notably social phobia. An additional attempt is made to examine findings based on a developmental perspective that accounts for multiple pathways, context, and the developmental stage of the child. Emotion regulation theory is offered as a potential factor in why some children may be more vulnerable to the etiologic factors described. Suggestions for future research are offered based on this integration of information.

  10. Federal Geothermal Research Program Update Fiscal Year 2000

    Energy Technology Data Exchange (ETDEWEB)

    Renner, J.L.

    2001-08-15

    The Department of Energy's Geothermal Program serves two broad purposes: (1) to assist industry in overcoming near-term barriers by conducting cost-shared research and field verification that allows geothermal energy to compete in today's aggressive energy markets; and (2) to undertake fundamental research with potentially large economic payoffs. The four categories of work used to distinguish the research activities of the Geothermal Program during FY 2000 reflect the main components of real-world geothermal projects. These categories form the main sections of the project descriptions in this Research Update. Exploration Technology research focuses on developing instruments and techniques to discover hidden hydrothermal systems and to explore the deep portions of known systems. Research in geophysical and geochemical methods is expected to yield increased knowledge of hidden geothermal systems. Reservoir Technology research combines laboratory and analytical investigations with equipment development and field testing to establish practical tools for resource development and management for both hydrothermal reservoirs and enhanced geothermal systems. Research in various reservoir analysis techniques is generating a wide range of information that facilitates development of improved reservoir management tools. Drilling Technology focuses on developing improved, economic drilling and completion technology for geothermal wells. Ongoing research to avert lost circulation episodes in geothermal drilling is yielding positive results. Conversion Technology research focuses on reducing costs and improving binary conversion cycle efficiency, to permit greater use of the more abundant moderate-temperature geothermal resource, and on the development of materials that will improve the operating characteristics of many types of geothermal energy equipment. Increased output and improved performance of binary cycles will result from investigations in heat cycle research.

  11. Federal Geothermal Research Program Update Fiscal Year 2000; ANNUAL

    International Nuclear Information System (INIS)

    Renner, J.L.

    2001-01-01

    The Department of Energy's Geothermal Program serves two broad purposes: (1) to assist industry in overcoming near-term barriers by conducting cost-shared research and field verification that allows geothermal energy to compete in today's aggressive energy markets; and (2) to undertake fundamental research with potentially large economic payoffs. The four categories of work used to distinguish the research activities of the Geothermal Program during FY 2000 reflect the main components of real-world geothermal projects. These categories form the main sections of the project descriptions in this Research Update. Exploration Technology research focuses on developing instruments and techniques to discover hidden hydrothermal systems and to explore the deep portions of known systems. Research in geophysical and geochemical methods is expected to yield increased knowledge of hidden geothermal systems. Reservoir Technology research combines laboratory and analytical investigations with equipment development and field testing to establish practical tools for resource development and management for both hydrothermal reservoirs and enhanced geothermal systems. Research in various reservoir analysis techniques is generating a wide range of information that facilitates development of improved reservoir management tools. Drilling Technology focuses on developing improved, economic drilling and completion technology for geothermal wells. Ongoing research to avert lost circulation episodes in geothermal drilling is yielding positive results. Conversion Technology research focuses on reducing costs and improving binary conversion cycle efficiency, to permit greater use of the more abundant moderate-temperature geothermal resource, and on the development of materials that will improve the operating characteristics of many types of geothermal energy equipment. Increased output and improved performance of binary cycles will result from investigations in heat cycle research

  12. Naval Research Reviews. Volume XXXIV. Number 4,

    Science.gov (United States)

    1982-01-01

    Dr. J. T. Lester Associate Scientific Editor Dr. D. A. Patterson Managing Editor M. J. Whetstone 2 AV Chief Writer/Editor W. J. Lescure, III Art ...and transdisciplinary research in many areas of ing science, essential to its objective of realizing research which are of naval interest. Indeed, the...and building The state-of-the- art as briefly described above is procedures to mimic the human capabilities not sufficient to build the more advanced

  13. 77 FR 20006 - Reports and Updates on Programs and Research Projects

    Science.gov (United States)

    2012-04-03

    ... From the Federal Register Online via the Government Publishing Office ARCTIC RESEARCH COMMISSION Reports and Updates on Programs and Research Projects Notice is hereby given that the U.S. Arctic Research... be reports and updates on programs and research projects affecting the Arctic. If you plan to attend...

  14. Computing for magnetic fusion energy research: An updated vision

    International Nuclear Information System (INIS)

    Henline, P.; Giarrusso, J.; Davis, S.; Casper, T.

    1993-01-01

    This Fusion Computing Council perspective is written to present the primary of the fusion computing community at the time of publication of the report necessarily as a summary of the information contained in the individual sections. These concerns reflect FCC discussions during final review of contributions from the various working groups and portray our latest information. This report itself should be considered as dynamic, requiring periodic updating in an attempt to track rapid evolution of the computer industry relevant to requirements for magnetic fusion research. The most significant common concern among the Fusion Computing Council working groups is networking capability. All groups see an increasing need for network services due to the use of workstations, distributed computing environments, increased use of graphic services, X-window usage, remote experimental collaborations, remote data access for specific projects and other collaborations. Other areas of concern include support for workstations, enhanced infrastructure to support collaborations, the User Service Centers, NERSC and future massively parallel computers, and FCC sponsored workshops

  15. A Research on a Certain Family of Numbers and Polynomials Related to Stirling Numbers, Central Factorial Numbers, and Euler Numbers

    Directory of Open Access Journals (Sweden)

    J. Y. Kang

    2013-01-01

    Full Text Available Recently, many mathematicians have studied different kinds of the Euler, Bernoulli, and Genocchi numbers and polynomials. In this paper, we give another definition of polynomials Ũn(x. We observe an interesting phenomenon of “scattering” of the zeros of the polynomials Ũn(x in complex plane. We find out some identities and properties related to polynomials Ũn(x. Finally, we also derive interesting relations between polynomials Ũn(x, Stirling numbers, central factorial numbers, and Euler numbers.

  16. DNA Damage Repair System in Plants: A Worldwide Research Update.

    Science.gov (United States)

    Gimenez, Estela; Manzano-Agugliaro, Francisco

    2017-10-30

    Living organisms are usually exposed to various DNA damaging agents so the mechanisms to detect and repair diverse DNA lesions have developed in all organisms with the result of maintaining genome integrity. Defects in DNA repair machinery contribute to cancer, certain diseases, and aging. Therefore, conserving the genomic sequence in organisms is key for the perpetuation of life. The machinery of DNA damage repair (DDR) in prokaryotes and eukaryotes is similar. Plants also share mechanisms for DNA repair with animals, although they differ in other important details. Plants have, surprisingly, been less investigated than other living organisms in this context, despite the fact that numerous lethal mutations in animals are viable in plants. In this manuscript, a worldwide bibliometric analysis of DDR systems and DDR research in plants was made. A comparison between both subjects was accomplished. The bibliometric analyses prove that the first study about DDR systems in plants (1987) was published thirteen years later than that for other living organisms (1975). Despite the increase in the number of papers about DDR mechanisms in plants in recent decades, nowadays the number of articles published each year about DDR systems in plants only represents 10% of the total number of articles about DDR. The DDR research field was done by 74 countries while the number of countries involved in the DDR & Plant field is 44. This indicates the great influence that DDR research in the plant field currently has, worldwide. As expected, the percentage of studies published about DDR systems in plants has increased in the subject area of agricultural and biological sciences and has diminished in medicine with respect to DDR studies in other living organisms. In short, bibliometric results highlight the current interest in DDR research in plants among DDR studies and can open new perspectives in the research field of DNA damage repair.

  17. Aviation Climate Change Research Initiative (ACCRI) - An Update

    Science.gov (United States)

    Gupta, M. L.

    2009-12-01

    Aviation plays an important role in global and domestic economic development and transport mobility. There are environmental concerns associated with aviation noise and emissions. Aircraft climate impacts are primarily due to release of emissions at the cruise altitude in the upper troposphere and lower stratosphere. Even though small in magnitude at present, aviation climate impacts will likely increase with projected growth in air transport demand unless scientifically informed and balanced mitigation solutions are implemented in a timely manner. There are large uncertainties associated with global and regional non-CO2 aviation climate impacts which need to be well quantified and constrained to support decision making. To meet future aviation capacity needs, the United States is developing and implementing a dynamic, flexible and scalable Next Generation Air Transportation System (NextGen) that is safe, secure, efficient and environmentally sound. One of the stated NextGen environmental goals is to limit or reduce the impacts of aviation emissions on global climate. With the support from the participating agencies of the U.S. Climate Change Science Program, the Federal Aviation Administration (FAA) has developed Aviation Climate Change Research Initiative (ACCRI) with the main objective to identify and address key scientific gaps and uncertainties that are most likely to be achieved in near (up to 18 months) and mid (up to 36 months) term horizons while providing timely scientific input to inform decision making. Till date, ACCRI funded activities have resulted in release of 8 subject-specific whitepapers and a report on The Way Forward. These documents can be accessed via http://www.faa.gov/about/office_org/headquarters_offices/aep/aviation_climate/media/ACCRI_Report_final.pdf. This presentation will provide details on prioritized key scientific gaps and uncertainties to better characterize aviation climate impacts. This presentation will also include a brief

  18. Minority University Research and Education Division (MURED) Update

    Science.gov (United States)

    Malone, John

    2000-01-01

    Program priorities include: (1) Expand and advance NASA's scientific and technological base by building on prior year's efforts in research and academic infrastructure; (2) Increase exposure to NASA's unique mission and facilities by developing closer relationships with NASA Strategic Enterprises; (3) Increase involvement in competitive peer review and merit selection processes; (4) Contribute significantly to the Agency's strategic goals and objectives; (5) Create systemic and sustainable change through partnerships and programs that enhance research and education programs; (6) Prepare faculty and students at HBCU's for NASA-related fields and increase number of students that enter and successfully complete degrees in NASA-related fields; (7) Establish measurable program goals and objectives; and (8) Improve financial management performance.

  19. JSTO Science and Technology Update. Volume 1, Number 2, Winter 2011

    Science.gov (United States)

    2011-01-01

    and that drives the urgency to transition these advances to capabilities. The evening ended with the presentation of conference awards by Dr. Rudolph...See IBRD page 10 10JSTO SCIENCE AND TECHNOLOGY UPDATE | Winter 2011 using Rapid Viability- PCR . The High-Throughput Sample Process for Outdoor... urgency to develop a countermeasure that can protect first responders in a radiation exposure field for both rescue and military operations. This

  20. Federal Geothermal Research Program Update - Fiscal Year 2004

    Energy Technology Data Exchange (ETDEWEB)

    Patrick Laney

    2005-03-01

    The Department of Energy (DOE) and its predecessors have conducted research and development (R&D) in geothermal energy since 1971. The Geothermal Technologies Program (GTP) works in partnership with industry to establish geothermal energy as an economically competitive contributor to the U.S. energy supply. Geothermal energy production, a $1.5 billion a year industry, generates electricity or provides heat for direct use applications. The technologies developed by the Geothermal Technologies Program will provide the Nation with new sources of electricity that are highly reliable and cost competitive and do not add to America's air pollution or the emission of greenhouse gases. Geothermal electricity generation is not subject to fuel price volatility and supply disruptions from changes in global energy markets. Geothermal energy systems use a domestic and renewable source of energy. The Geothermal Technologies Program develops innovative technologies to find, access, and use the Nation's geothermal resources. These efforts include emphasis on Enhanced Geothermal Systems (EGS) with continued R&D on geophysical and geochemical exploration technologies, improved drilling systems, and more efficient heat exchangers and condensers. The Geothermal Technologies Program is balanced between short-term goals of greater interest to industry, and long-term goals of importance to national energy interests. The program's research and development activities are expected to increase the number of new domestic geothermal fields, increase the success rate of geothermal well drilling, and reduce the costs of constructing and operating geothermal power plants. These improvements will increase the quantity of economically viable geothermal resources, leading in turn to an increased number of geothermal power facilities serving more energy demand. These new geothermal projects will take advantage of geothermal resources in locations where development is not currently possible or

  1. Federal Geothermal Research Program Update Fiscal Year 2004

    Energy Technology Data Exchange (ETDEWEB)

    2005-03-01

    The Department of Energy (DOE) and its predecessors have conducted research and development (R&D) in geothermal energy since 1971. The Geothermal Technologies Program (GTP) works in partnership with industry to establish geothermal energy as an economically competitive contributor to the U.S. energy supply. Geothermal energy production, a $1.5 billion a year industry, generates electricity or provides heat for direct use applications. The technologies developed by the Geothermal Technologies Program will provide the Nation with new sources of electricity that are highly reliable and cost competitive and do not add to America's air pollution or the emission of greenhouse gases. Geothermal electricity generation is not subject to fuel price volatility and supply disruptions from changes in global energy markets. Geothermal energy systems use a domestic and renewable source of energy. The Geothermal Technologies Program develops innovative technologies to find, access, and use the Nation's geothermal resources. These efforts include emphasis on Enhanced Geothermal Systems (EGS) with continued R&D on geophysical and geochemical exploration technologies, improved drilling systems, and more efficient heat exchangers and condensers. The Geothermal Technologies Program is balanced between short-term goals of greater interest to industry, and long-term goals of importance to national energy interests. The program's research and development activities are expected to increase the number of new domestic geothermal fields, increase the success rate of geothermal well drilling, and reduce the costs of constructing and operating geothermal power plants. These improvements will increase the quantity of economically viable geothermal resources, leading in turn to an increased number of geothermal power facilities serving more energy demand. These new geothermal projects will take advantage of geothermal resources in locations where development is not currently

  2. Global foot-and-mouth disease research update and gap analysis: 6 - immunology

    Science.gov (United States)

    In 2014, the Global Foot-and-mouth disease Research Alliance (GFRA) conducted a gap analysis of FMD research. This has been updated with findings reported in a series of papers. Here we present findings for FMD immunology research. The paper consists of the following four sections: 1. Research prior...

  3. Global foot-and-mouth disease research update and gap analysis: 3 - vaccines

    Science.gov (United States)

    In 2014, the Global Foot-and-mouth disease Research Alliance (GFRA) conducted a gap analysis of FMD research. In this paper, we report updated findings in the field of FMD vaccine research. This paper consists of the following four sections: 1) Research priorities identified in the 2010 GFRA gap ana...

  4. Current Pharmacologic Approaches in Painful Bladder Research: An Update

    Science.gov (United States)

    2017-01-01

    The symptoms of interstitial cystitis (IC)/bladder pain syndrome (BPS) may have multiple causes and involve many contributing factors. Traditional treatments (intravesical instillations) have had a primary focus on the bladder as origin of symptoms without adequately considering the potential influence of other local (pelvic) or systemic factors. Systemic pharmacological treatments have had modest success. A contributing factor to the low efficacy is the lack of phenotyping the patients. Individualized treatment based on is desirable, but further phenotype categorization is needed. There seems to be general agreement that IC is a unique disease and that BPS is a syndrome with multiple pathophysiologies, but this has so far not been not been well reflected in preclinical research with the aim of finding new pharmacological treatments. Current research approaches, including anti-nerve growth factor treatment, anti-tumor necrosis factor-α treatment, activation of SHIP1 (AQX-1125), and P2X3 receptor antagonists, and α1-adrenoceptor antagonists are potential systemic treatments, implying that not only the bladder is exposed to the administered drug, which may be beneficial if the IC/BPS is a bladder manifestation of a systemic disease, or negative (adverse effects) if it is a local bladder condition. Local treatment approaches such as the antagonism of Toll-like receptors (which still is only experimental) and intravesical liposomes (with positive proof-of-concept), may have the advantages of a low number of systemic adverse effects, but cannot be expected to have effects on symptoms generated outside the bladder. Assessment of which of the treatment approaches discussed in this review that can be developed into useful therapies requires further studies. PMID:29298474

  5. Individual determinants of research utilization by nurses: a systematic review update

    Science.gov (United States)

    2011-01-01

    Background Interventions that have a better than random chance of increasing nurses' use of research are important to the delivery of quality patient care. However, few reports exist of successful research utilization in nursing interventions. Systematic identification and evaluation of individual characteristics associated with and predicting research utilization may inform the development of research utilization interventions. Objective To update the evidence published in a previous systematic review on individual characteristics influencing research utilization by nurses. Methods As part of a larger systematic review on research utilization instruments, 12 online bibliographic databases were searched. Hand searching of specialized journals and an ancestry search was also conducted. Randomized controlled trials, clinical trials, and observational study designs examining the association between individual characteristics and nurses' use of research were eligible for inclusion. Studies were limited to those published in the English, Danish, Swedish, and Norwegian languages. A vote counting approach to data synthesis was taken. Results A total of 42,770 titles were identified, of which 501 were retrieved. Of these 501 articles, 45 satisfied our inclusion criteria. Articles assessed research utilization in general (n = 39) or kinds of research utilization (n = 6) using self-report survey measures. Individual nurse characteristics were classified according to six categories: beliefs and attitudes, involvement in research activities, information seeking, education, professional characteristics, and socio-demographic/socio-economic characteristics. A seventh category, critical thinking, emerged in studies examining kinds of research utilization. Positive relationships, at statistically significant levels, for general research utilization were found in four categories: beliefs and attitudes, information seeking, education, and professional characteristics. The only

  6. Individual determinants of research utilization by nurses: a systematic review update

    Directory of Open Access Journals (Sweden)

    Wallin Lars

    2011-01-01

    Full Text Available Abstract Background Interventions that have a better than random chance of increasing nurses' use of research are important to the delivery of quality patient care. However, few reports exist of successful research utilization in nursing interventions. Systematic identification and evaluation of individual characteristics associated with and predicting research utilization may inform the development of research utilization interventions. Objective To update the evidence published in a previous systematic review on individual characteristics influencing research utilization by nurses. Methods As part of a larger systematic review on research utilization instruments, 12 online bibliographic databases were searched. Hand searching of specialized journals and an ancestry search was also conducted. Randomized controlled trials, clinical trials, and observational study designs examining the association between individual characteristics and nurses' use of research were eligible for inclusion. Studies were limited to those published in the English, Danish, Swedish, and Norwegian languages. A vote counting approach to data synthesis was taken. Results A total of 42,770 titles were identified, of which 501 were retrieved. Of these 501 articles, 45 satisfied our inclusion criteria. Articles assessed research utilization in general (n = 39 or kinds of research utilization (n = 6 using self-report survey measures. Individual nurse characteristics were classified according to six categories: beliefs and attitudes, involvement in research activities, information seeking, education, professional characteristics, and socio-demographic/socio-economic characteristics. A seventh category, critical thinking, emerged in studies examining kinds of research utilization. Positive relationships, at statistically significant levels, for general research utilization were found in four categories: beliefs and attitudes, information seeking, education, and professional

  7. Dementia Caregiver Burden: a Research Update and Critical Analysis.

    Science.gov (United States)

    Cheng, Sheung-Tak

    2017-08-10

    This article provides an updated review of the determinants of caregiver burden and depression, with a focus on care demands and especially the differential effects of various neuropsychiatric symptoms or symptom clusters. Moreover, studies on caregivers for frontotemporal and Lewy body dementias were referred to in order to identify differences and similarities with the mainstream literature based largely on Alzheimer caregivers. As a group, neuropsychiatric symptoms are most predictive of caregiver burden and depression regardless of dementia diagnosis, but the effects appear to be driven primarily by disruptive behaviors (e.g., agitation, aggression, disinhibition), followed by delusions and mood disturbance. Disruptive behaviors are more disturbing partly because of the adverse impact on the emotional connection between the caregiver and the care-recipient and partly because they exacerbate difficulties in other domains (e.g., caring for activities of daily living). In behavioral variant frontotemporal dementia, not only are these disruptive behaviors more prominent but they are also more disturbing due to the care-recipient's insensitivity to others' feelings. In Lewy body dementia, visual hallucinations also appear to be distressing. The disturbing nature of disruptive behaviors cuts across dementia conditions, but the roles played by symptoms that are unique or particularly serious in a certain condition need to be explored further.

  8. Nondestructive testing and evaluation of wood : a worldwide research update

    Science.gov (United States)

    Brian K. Brashaw; Voichita Bucur; Ferenc Divos; Raquel Goncalves; Jianxiong Lu; Roger Meder; Roy F. Pellerin; Simon Potter; Robert J Ross; Xiping Wang; Yafang. Yin

    2009-01-01

    The international forest products research community is responding to these driving forces by conducting NDT/NDE research to provide the technologies needed to address these challenges. This article presents a sample of the on-going NDT/NDE research efforts being conducted in several areas of the world.

  9. Global foot-and-mouth disease research update and gap analysis: 7 - pathogenesis and molecular biology

    Science.gov (United States)

    In 2014, the GFRA (Global Foot-and-mouth disease Research Alliance) conducted a gap analysis of FMD (Foot-and-Mouth Disease) research. This work has been updated and reported in a series of papers, in this article we report findings in the fields of 1) pathogenesis and 2) molecular biology. The arti...

  10. ARS irrigation research priorities and projects-An update

    Science.gov (United States)

    The USDA Agricultural Research Service focuses on six areas of research that are crucial to safe and effective use of all water resources for agricultural production: 1) Irrigation Scheduling Technologies for Water Productivity; 2) Water Productivity (WP) at Multiple Scales; 3) Irrigation Applicatio...

  11. Development of Prototype Driver Models for Highway Design: Research Update

    Science.gov (United States)

    1999-06-01

    One of the high-priority research areas of the Federal Highway Administration (FHWA) is the development of the Interactive Highway Safety Design Model (IHSDM). The goal of the IHSDM research program is to develop a systematic approach that will allow...

  12. Federal Geothermal Research Program Update Fiscal Year 1998

    Energy Technology Data Exchange (ETDEWEB)

    Keller, J.G.

    1999-05-01

    This report reviews the specific objectives, status, and accomplishments of DOE's Geothermal Research Program for Fiscal Year 1998. The Exploration Technology research area focuses on developing instruments and techniques to discover hidden hydrothermal systems and to expose the deep portions of known systems. The Reservoir Technology research combines laboratory and analytical investigations with equipment development and field testing to establish practical tools for resource development and management for both hydrothermal and hot dry rock reservoirs. The Drilling Technology projects focus on developing improved, economic drilling and completion technology for geothermal wells. The Conversion Technology research focuses on reducing costs and improving binary conversion cycle efficiency, to permit greater use of the more abundant moderate-temperature geothermal resource, and on the development of materials that will improve the operating characteristics of many types of geothermal energy equipment. Direct use research covers the direct use of geothermal energy sources for applications in other than electrical production.

  13. Low-carbohydrate diets: an update on current research.

    Science.gov (United States)

    Wylie-Rosett, Judith; Davis, Nichola J

    2009-10-01

    The diabetes and obesity epidemics have stimulated research to assess the benefits and potential risks of low-carbohydrate diets. Carbohydrate comprises less than 45% of calories in carbohydrate-restricted diets, but very low carbohydrate ketogenic diets may restrict carbohydrate to 20 g initially with variability in the carbohydrate level subsequently. Some research suggests that low-carbohydrate diets may achieve better early weight loss than comparison diets higher in carbohydrate. Studies of up to 1 year suggest that weight loss on low-carbohydrate diet is comparable with fat-restricted diets with higher carbohydrate content. Limited research has been conducted to evaluate low-carbohydrate diets in managing type 2 diabetes. Although science continues to advance in this field, current research suggests that low-carbohydrate diets can be a viable option for achieving weight loss and may have beneficial effects on glycemic control, triglyceride levels, and high-density lipoprotein cholesterol levels in some patients.

  14. Building America Research Benchmark Definition, Updated December 19, 2008

    Energy Technology Data Exchange (ETDEWEB)

    Hendron, R. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2008-12-19

    To track progress toward aggressive multi-year whole-house energy savings goals of 40-70% and onsite power production of up to 30%, DOE's Residential Buildings Program and NREL developed the Building America Research Benchmark in consultation with the Bui

  15. Building America Research Benchmark Definition: Updated December 19, 2008

    Energy Technology Data Exchange (ETDEWEB)

    Hendron, R.

    2008-12-01

    To track progress toward aggressive multi-year whole-house energy savings goals of 40-70% and onsite power production of up to 30%, DOE's Residential Buildings Program and NREL developed the Building America Research Benchmark in consultation with the Building America industry teams.

  16. Building America Research Benchmark Definition, Updated December 2009

    Energy Technology Data Exchange (ETDEWEB)

    Hendron, Robert [National Renewable Energy Lab. (NREL), Golden, CO (United States); Engebrecht, Cheryn [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2010-01-01

    To track progress toward aggressive multi-year, whole-house energy savings goals of 40%–70% and on-site power production of up to 30%, the U.S. Department of Energy (DOE) Residential Buildings Program and the National Renewable Energy Laboratory (NREL) developed the Building America (BA) Research Benchmark in consultation with the Building America industry teams.

  17. Research Update: Enhancing the Youth Sports Experience through Coaching.

    Science.gov (United States)

    Steelman, Todd

    1995-01-01

    Reviews research on the relationship between youth sports coaches and players, noting that the youth sports coach can be the most important figure in socializing children in the area of sports. The paper discusses how to deal with the stresses in coaching and examines the need for coach effectiveness training. (SM)

  18. Results from oil spill response research - an update

    International Nuclear Information System (INIS)

    Tennyson, E.J.

    1993-01-01

    Recent large oil spills from tankers have reaffirmed the need for continuing technology assessment and research to improve oil spill response capabilities. This paper discusses Minerals Management Service concerns, as reinforced by the acceleration of its research program in 1990. It briefly assesses current state-of-the-art technology for major aspects of spill response, including remote sensing, open-ocean containment and recovery, in-situ burning, use of chemical treating agents, beachline cleanup, and oil behavior. Specific research projects have begun to yield information that will improve detection and at-sea equipment performance; current projects include the development of an airborne laser-fluorosensor to determine whether apparent slicks contain oil. Additional projects involve the development of improved strategies for responding to oil in broken-ice conditions, for gaining an improved understanding of the fate and behavior of spilled oil as it affects response strategies, and for defining the capabilities of available dispersants and development of improved formulations. Recently, progress has been made on the development of safe and environmentally acceptable strategies to burn spilled oil in situ. The Ohmsett facility has been reopened and will be used to test prospective improvements in chemical treating agents and to develop standard procedures for testing and evaluating response equipment. Results of research published since the last Oil Spill Conference are discussed

  19. Choke in orchardgrass: research update and potential control

    Science.gov (United States)

    Choke, caused by the endophytic fungus Epichloe typhina is a serious and persistent problem in orchardgrass seed production fields. Recent research on choke has provided new insight into the biology and epidemiology of E. typhina. Fungicides for prevention of infection have not proven effective. How...

  20. Research in Osteochondritis Dissecans of the Knee: 2016 Update.

    Science.gov (United States)

    Nepple, Jeffrey J; Milewski, Matthew D; Shea, Kevin G

    2016-10-01

    Osteochondritis dissecans (OCD) of the knee remains a relatively common and poorly understood pediatric and adolescent knee condition. Both conservative and surgical treatments have major impact on the lives of young active, athletic patients with knee OCD. OCD has been recently redefined as a "focal, idiopathic alteration of subchondral bone with risk for instability and disruption of adjacent articular cartilage that may result in premature osteoarthritis." The 2011 American Academy of Orthopedic Surgeons Clinical Practice Guidelines found limited evidence for all aspects of the treatment of knee OCD. The multicenter study group Research in Osteochondritis dissecans of the Knee (ROCK) was formed to advance the understanding and treatment of this condition. This article will review our current understanding of the pathophysiology, treatment options, and outcomes of OCD of the knee, with a focus on the past, present, and future research including the work of the ROCK study group. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  1. UNENE: an update on nuclear education and research

    International Nuclear Information System (INIS)

    Shalaby, B.A.; Snell, V.G.; Rouben, B.

    2011-01-01

    University Network for Excellence in Nuclear Engineering (known as UNENE) was created in 2002 as a partnership between Industry and universities with the objectives of establishing a nuclear R and D program in universities to train and develop Highly Qualified Personnel (HQP) to address the demographic gap and to create a sustainable source of expertise for independent industry and public consultation. Seven years into its creation, UNENE is now a well established and fully functional framework with programs mainly focussing on education and research serving the industry at large. The educational component is in the form of an M. Eng program mainly catering for working profession's by being offered on weekends and using distance learning tools. It is intended to enhance competencies and build knowledge for students. The R and D programs are lead by Industrial Research chairs (IRCs) and other prominent researchers in areas of importance to the industry. This paper examines the above topics and its outcomes as of March 2010. (author)

  2. Update in research and methods in proteomics and bioinformatics.

    Science.gov (United States)

    Bencharit, Sompop; Border, Michael B; Edelmann, Alex; Byrd, Warren C

    2013-10-01

    The 3rd International Conference on Proteomics & Bioinformatics (Proteomics 2013) Philadelphia, PA, USA, 15-17 July 2013 The Third International Conference on Proteomics & Bioinformatics (Proteomics 2013) was sponsored by the OMICS group and was organized in order to strengthen the future of proteomics science by bringing together professionals, researchers and scholars from leading universities across the globe. The main topics of this conference included the integration of novel platforms in data analysis, the use of a systems biology approach, different novel mass spectrometry platforms and biomarker discovery methods. The conference was divided into proteomic methods and research interests. Among these two categories, interactions between methods in proteomics and bioinformatics, as well as other research methodologies, were discussed. Exceptional topics from the keynote forum, oral presentations and the poster session have been highlighted. The topics range from new techniques for analyzing proteomics data, to new models designed to help better understand genetic variations to the differences in the salivary proteomes of HIV-infected patients.

  3. Wind Energy in the United States: Market and Research Update

    International Nuclear Information System (INIS)

    Goldman, P.R.; Thresher, R.W.; Hock, S.M.

    1999-01-01

    U.S. market activity has increased over the last two years. In 1998, new capacity totaled about 150 MW and projected 1999 capacity additions are over 600 MW. As the electricity market continues to evolve under restructuring, the U.S. Department of Energy (U.S. DOE) Wind Energy Program has positioned itself to work with industry to meet current challenges and opportunities, and prepare for the market of tomorrow. Some opportunities include green power markets and distributed applications, although a primary challenge involves the fact that avoided cost payments to renewable generators are not high enough to economically support projects. A recently incorporated power exchange in California, APX, Inc., has demonstrated that green power does attract a premium over prices on the conventional power exchange. The key elements of the U.S. DOE Wind Program are (1) Applied Research, which is critical for achieving advanced turbine designs capable of competing in a restructured market that emphasizes low cost generation; (2) Turbine Research, which supports the U.S. industry in developing competitive, high performance, reliable wind turbine technology for global energy markets; and (3) Cooperative Research and Testing, under which standards development and certification testing are the key activities for the current year

  4. Quality of Life in Individuals with Spina Bifida: A Research Update

    Science.gov (United States)

    Sawin, Kathleen J.; Bellin, Melissa H.

    2010-01-01

    Quality of life (QOL) is an important concept for individuals with chronic health conditions. Measuring and supporting QOL in children, adolescents, and adults with spina bifida (SB) may be especially unique given the broad range of complex health and rehabilitative challenges they encounter. This article provides a research update on (a)…

  5. A Dialogic about Using Facebook Status Updates for Education Research: A PhD Student's Journey

    Science.gov (United States)

    Barnes, Naomi; Penn-Edwards, Sorrel; Sim, Cheryl

    2015-01-01

    Facebook status updates provided the data for a study about the transition learning experiences of 1st-year university students. Strict ethical guidelines were proposed by the PhD researcher from the outset of the study. Anonymity was considered important for the approved ethical clearance for both the university and the participants.…

  6. An updated method for risk adjustment in outcomes research.

    Science.gov (United States)

    Doi, Suhail A R; Barendregt, Jan J; Rao, Chalapati

    2014-07-01

    To demonstrate why meta-analytic methods need modification before they can be used to aggregate rates or effect sizes in outcomes research, under the constraint of no common underlying effect or rate. Studies are presented that require different types of risk adjustment. First, we demonstrate using rates that external risk adjustment through standardization can be achieved using modified meta-analytic methods, but only with a model that allows input of user-defined weights. Next, we extend these observations to internal risk adjustment of comparative effect sizes. We show that this procedure produces identical results to conventional age standardization if a rate is being standardized for age. We also demonstrate that risk adjustment of effect sizes can be achieved with this modified method but cannot be done using standard meta-analysis. We conclude that this method allows risk adjustment to be performed in situations in which currently the fixed- or random-effects methods of meta-analysis are inappropriately used. The latter should be avoided when the underlying aim is risk adjustment rather than meta-analysis. Copyright © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  7. Building America Research Benchmark Definition: Updated December 20, 2007

    Energy Technology Data Exchange (ETDEWEB)

    Hendron, R.

    2008-01-01

    To track progress toward aggressive multi-year whole-house energy savings goals of 40-70% and onsite power production of up to 30%, DOE's Residential Buildings Program and NREL developed the Building America Research Benchmark in consultation with the Building America industry teams. The Benchmark is generally consistent with mid-1990s standard practice, as reflected in the Home Energy Rating System (HERS) Technical Guidelines (RESNET 2002), with additional definitions that allow the analyst to evaluate all residential end-uses, an extension of the traditional HERS rating approach that focuses on space conditioning and hot water. Unlike the reference homes used for HERS, EnergyStar, and most energy codes, the Benchmark represents typical construction at a fixed point in time so it can be used as the basis for Building America's multi-year energy savings goals without the complication of chasing a 'moving target'.

  8. Building America Research Benchmark Definition, Updated December 29, 2004

    Energy Technology Data Exchange (ETDEWEB)

    Hendron, R.

    2005-02-01

    To track progress toward aggressive multi-year whole-house energy savings goals of 40-70% and onsite power production of up to 30%, the U.S. Department of Energy (DOE) Residential Buildings Program and the National Renewable Energy Laboratory (NREL) developed the Building America Research Benchmark in consultation with the Building America industry teams. The Benchmark is generally consistent with mid-1990s standard practice, as reflected in the Home Energy Rating System (HERS) Technical Guidelines (RESNET 2002), with additional definitions that allow the analyst to evaluate all residential end-uses, an extension of the traditional HERS rating approach that focuses on space conditioning and hot water. A series of user profiles, intended to represent the behavior of a ''standard'' set of occupants, was created for use in conjunction with the Benchmark.

  9. Building America Research Benchmark Definition, Updated December 15, 2006

    Energy Technology Data Exchange (ETDEWEB)

    Hendron, R.

    2007-01-01

    To track progress toward aggressive multi-year whole-house energy savings goals of 40-70% and onsite power production of up to 30%, DOE's Residential Buildings Program and NREL developed the Building America Research Benchmark in consultation with the Building America industry teams. The Benchmark is generally consistent with mid-1990s standard practice, as reflected in the Home Energy Rating System (HERS) Technical Guidelines (RESNET 2002), with additional definitions that allow the analyst to evaluate all residential end-uses, an extension of the traditional HERS rating approach that focuses on space conditioning and hot water. Unlike the reference homes used for HERS, EnergyStar, and most energy codes, the Benchmark represents typical construction at a fixed point in time so it can be used as the basis for Building America's multi-year energy savings goals without the complication of chasing a ''moving target''.

  10. Building America Research Benchmark Definition: Updated August 15, 2007

    Energy Technology Data Exchange (ETDEWEB)

    Hendron, R.

    2007-09-01

    To track progress toward aggressive multi-year whole-house energy savings goals of 40-70% and onsite power production of up to 30%, DOE's Residential Buildings Program and NREL developed the Building America Research Benchmark in consultation with the Building America industry teams. The Benchmark is generally consistent with mid-1990s standard practice, as reflected in the Home Energy Rating System (HERS) Technical Guidelines (RESNET 2002), with additional definitions that allow the analyst to evaluate all residential end-uses, an extension of the traditional HERS rating approach that focuses on space conditioning and hot water. Unlike the reference homes used for HERS, EnergyStar, and most energy codes, the Benchmark represents typical construction at a fixed point in time so it can be used as the basis for Building America's multi-year energy savings goals without the complication of chasing a 'moving target'.

  11. Significant events in psychotherapy: An update of research findings.

    Science.gov (United States)

    Timulak, Ladislav

    2010-11-01

    Significant events research represents a specific approach to studying client-identified important moments in the therapy process. The current study provides an overview of the significant events research conducted, the methodology used together with findings and implications. PsychInfo database was searched with keywords such as significant events, important events, significant moments, important moments, and counselling or psychotherapy. The references of the selected studies were also searched. This process led to the identification of 41 primary studies that used client-identified significant event(s) as a main or secondary focus of the study. These were consequently reviewed with regard to their methodology and findings. The findings are presented according to type of study conducted. The impacts of helpful events reported by clients are focused on contributions to therapeutic relationship and to in-session outcomes. Hindering events focus on some client disappointment with the therapist or therapy. The group therapy modality highlighted additional helpful impacts (like learning from others). Perspectives on what is significant in therapy differ between clients and therapists. The intensive qualitative studies reviewed confirm that the processes involved in significant events are complex and ambiguous. Studies show that the helpful events may also contain many hindering elements and that specific events are deeply contextually embedded in the preceding events of therapy. Some studies suggest that helpful significant events are therapeutically productive although this may need to be established further. Specific intensive studies show that the clients' perceptions in therapy may differ dramatically from that of the therapist. Furthermore, the relational and emotional aspects of significant moments may be more important for the clients than the cognitive aspects of therapy which are frequently stressed by therapists. 2010 The British Psychological Society.

  12. Research Update: Electrical monitoring of cysts using organic electrochemical transistors

    International Nuclear Information System (INIS)

    Huerta, M.; Rivnay, J.; Ramuz, M.; Hama, A.; Owens, R. M.

    2015-01-01

    Organotypic three-dimensional (3D) cell culture models have the potential to act as surrogate tissues in vitro, both for basic research and for drug discovery/toxicology. 3D cultures maintain not only 3D architecture but also cell-cell and cell extracellular matrix interactions, particularly when grown in cysts or spheroids. Characterization of cell cultures grown in 3D formats, however, provides a significant challenge for cell biologists due to the incompatibility of these structures with commonly found optical or electronic monitoring systems. Electronic impedance spectroscopy is a cell culture monitoring technique with great potential; however, it has not been possible to integrate 3D cultures with commercially available systems to date. Cyst-like 3D cultures are particularly challenging due to their small size and difficulty in manipulation. Herein, we demonstrate isolation of cyst-like 3D cultures by capillarity and subsequent integration with the organic electrochemical transistor for monitoring the integrity of these structures. We show not only that this versatile device can be adapted to the cyst format for measuring resistance and, therefore, the quality of the cysts, but also can be used for quantitative monitoring of the effect of toxic compounds on cells in a 3D format. The ability to quantitatively predict effects of drugs on 3D cultures in vitro has large future potential for the fields of drug discovery and toxicology

  13. Current practices and research updates on diabetes mellitus in canine

    Directory of Open Access Journals (Sweden)

    Pankaj Kumar

    2014-11-01

    Full Text Available Diabetes has evidence in ancient literatures, though recently is being considered as one amongst the most emerging disease condition in both human and companion animals. Diabetes mellitus is one of the common endocrinopathy of dog characterized by hyperglycemia, glycosuria and weight loss. Reports suggests high fraction of canine population suffer with diabetes world over. Studies in different veterinary hospitals of United States suggest increase in cases of canine diabetes and decrease in case fatality rate over time. Increase in cases of canine diabetes worldwide is attributed to awareness amongst pet owners, better veterinary health facilities, breed preferences by dog owners, increase dependence on commercial feeds, obesity, etc. Diabetes in most dogs is immune mediated and insulin dependent. Breed predisposition in canine is attributed to dog leukocyte antigen gene pool encoding form major histocompatibility complex-II molecules, however research is still underway. Diagnosis of diabetes still relies on blood sugar evaluation for screening of canine population, though many other diagnostic methods have shown promising benefits including measurement of fructosamine and glycated haemoglobin. Management of diabetes in dog is based on insulin therapy, diet modification and exercise. Use of oral anti-diabetics drugs in canine is limited though experimental studies have shown promising results. Alternative therapies have been explored, but only a few approaches have shown promise for clinical application.

  14. The 2014 Nucleic Acids Research Database Issue and an updated NAR online Molecular Biology Database Collection.

    Science.gov (United States)

    Fernández-Suárez, Xosé M; Rigden, Daniel J; Galperin, Michael Y

    2014-01-01

    The 2014 Nucleic Acids Research Database Issue includes descriptions of 58 new molecular biology databases and recent updates to 123 databases previously featured in NAR or other journals. For convenience, the issue is now divided into eight sections that reflect major subject categories. Among the highlights of this issue are six databases of the transcription factor binding sites in various organisms and updates on such popular databases as CAZy, Database of Genomic Variants (DGV), dbGaP, DrugBank, KEGG, miRBase, Pfam, Reactome, SEED, TCDB and UniProt. There is a strong block of structural databases, which includes, among others, the new RNA Bricks database, updates on PDBe, PDBsum, ArchDB, Gene3D, ModBase, Nucleic Acid Database and the recently revived iPfam database. An update on the NCBI's MMDB describes VAST+, an improved tool for protein structure comparison. Two articles highlight the development of the Structural Classification of Proteins (SCOP) database: one describes SCOPe, which automates assignment of new structures to the existing SCOP hierarchy; the other one describes the first version of SCOP2, with its more flexible approach to classifying protein structures. This issue also includes a collection of articles on bacterial taxonomy and metagenomics, which includes updates on the List of Prokaryotic Names with Standing in Nomenclature (LPSN), Ribosomal Database Project (RDP), the Silva/LTP project and several new metagenomics resources. The NAR online Molecular Biology Database Collection, http://www.oxfordjournals.org/nar/database/c/, has been expanded to 1552 databases. The entire Database Issue is freely available online on the Nucleic Acids Research website (http://nar.oxfordjournals.org/).

  15. Updating to the WAIS-III and WMS-III: considerations for research and clinical practice.

    Science.gov (United States)

    Tulsky, David S; Ledbetter, Mark F

    2000-09-01

    The Wechsler Adult Intelligence Scale-Revised (WAIS-R) and the Wechsler Memory Scale-Revised (WMS-R) are the most commonly used intelligence and memory scales in both clinical and neuropsychology. In 1997, updated versions of these instruments (the WAIS-III and WMS-III) were published. Because of the extensive use of the WAIS-R and WMS-R in the field and the body of accumulated research, there is naturally some reluctance by clinicians and researchers to update to the new versions. It is sometimes difficult for clinicians who test individuals on repeated occasions to switch over to the new versions of the scales because of the difficulty of interpreting score discrepancy between the 2 versions. Researchers, especially those conducting longitudinal research, have a similar difficulty in changing measurement devices because of the possible threat of internal validity. This article reviews the substantive revisions of the scales and outlines those issues that users should take into consideration when updating to the new versions.

  16. The U.S. Geological Survey Amphibian Research and Monitoring Initiative-2011 Annual Update

    Science.gov (United States)

    Adams, M.J.; Muths, E.; Grant, E.H.C.; Miller, David A.; Waddle, J.H.; Ball, L.C.

    2012-01-01

    Welcome to the inaugural issue of ARMI's Annual Update. This update provides highlights and significant milestones of this innovative program. ARMI is uniquely qualified to provide research and monitoring results that are scalable from local to national levels, and are useful to resource managers. ARMI has produced nearly 400 peer-reviewed publications, including 18 in 2011. Some of those publications are highlighted in this fact sheet. ARMI also has a new Website (armi.usgs.gov). You can now use it to explore an up-to-date list of ARMI products, to find summaries of research topics, to search for ARMI activities in your area, and to obtain amphibian photographs. ARMI's annual meeting was organized by Walt Sadinski, Upper Midwest Environmental Science Center, and held in St Louis, Missouri. We met with local scientists and managers in herpetology and were given a tour of the herpetology collection at the St. Louis Zoo.

  17. New York State Energy Research and Development Authority. Research projects` update project status as of March 31, 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    This report provides an update of the New York State Energy Research and Development Authority (NYSERDA) program. The NYSERDA research and development program has five major areas: industry, buildings, energy resources, transportation, and environment. NYSERDA organizes projects within these five major areas based on energy use and supply, and end-use sectors. Therefore, issues such as waste management, energy products and renewable energy technologies are addressed in several areas of the program. The project descriptions presented are organized within the five program areas. Descriptions of projects completed between the period April 1, 1996, and March 31, 1997, including technology-transfer activities, are at the end of each subprogram section.

  18. Naval Research Logistics Quarterly. Volume 27, Number 2.

    Science.gov (United States)

    1980-06-01

    ZIMMERMANN solved using results of linear parametric programming. The number of columns k is equal to the dimension of the smallest affine hyperspace ...a feasi- ble transformation. For a given loop L and 8 < 0, the 8L transformation will be feasible if the odd-numbered cells of the loop are all...the transformation is feasible if the even numbered cells are positive-a requirement that ensures that yij - 8 will not become negative. In particular

  19. Research Update: Programmable tandem repeat proteins inspired by squid ring teeth

    Science.gov (United States)

    Pena-Francesch, Abdon; Domeradzka, Natalia E.; Jung, Huihun; Barbu, Benjamin; Vural, Mert; Kikuchi, Yusuke; Allen, Benjamin D.; Demirel, Melik C.

    2018-01-01

    Cephalopods have evolved many interesting features that can serve as inspiration. Repetitive squid ring teeth (SRT) proteins from cephalopods exhibit properties such as strength, self-healing, and biocompatibility. These proteins have been engineered to design novel adhesives, self-healing textiles, and the assembly of 2d-layered materials. Compared to conventional polymers, repetitive proteins are easy to modify and can assemble in various morphologies and molecular architectures. This research update discusses the molecular biology and materials science of polypeptides inspired by SRT proteins, their properties, and perspectives for future applications.

  20. December 2012 Policy Update: School Climate and Bully Prevention Trends State-by-State Assessment. School Climate Brief, Number 6

    Science.gov (United States)

    Bellizio, Dan

    2012-01-01

    This December 2012 Brief updates NSCC's 2011 report "State Policies on School Climate and Bully Prevention Efforts: Challenges and Opportunities for Deepening State Policy Support for Safe and Civil School"s (www.schoolclimate.org/climate/papers-briefs.php). This Brief provides a summary of State level: (1) anti-bullying legislation; (2)…

  1. An update of research examining college student alcohol-related consequences: new perspectives and implications for interventions.

    Science.gov (United States)

    Mallett, Kimberly A; Varvil-Weld, Lindsey; Borsari, Brian; Read, Jennifer P; Neighbors, Clayton; White, Helene R

    2013-05-01

    The objective of this review is to provide an update on existing research examining alcohol-related consequences among college students with relevance for individual-based interventions. While alcohol-related consequences have been a focus of study for several decades, the literature has evolved into an increasingly nuanced understanding of individual and environmental circumstances that contribute to risk of experiencing consequences. A number of risk factors for experiencing alcohol-related consequences have been identified, including belonging to specific student subgroups (e.g., Greek organizations) or drinking during high-risk periods, such as spring break. In addition, the relationship between students' evaluations of both negative and positive consequences and their future drinking behavior has become a focus of research. The current review provides an overview of high-risk student subpopulations, high-risk windows and activities, and college students' subjective evaluations of alcohol-related consequences. Future directions for research are discussed and include determining how students' orientations toward consequences change over time, identifying predictors of membership in high-risk consequence subgroups and refining existing measures of consequences to address evolving research questions. Copyright © 2012 by the Research Society on Alcoholism.

  2. Defense Acquisition Research Journal. Volume 21, Number 1, Issue 68

    Science.gov (United States)

    2014-01-01

    21 No. 1: 486–504 Principles from microeconomic theory and operations research can provide insight into acquisition decisions to produce military...Schedule Its Due Chad Dacus and Col Stephen Hagel, USAF (Ret.) Conceptual models based on economic and operations research principles can yield...secure software design principles . In cases where a critical system must be controlled and disseminated to trusted individuals, entry into the VM is

  3. GSD Update: Year in Review: Spotlight on 2013 research by the Grassland, Shrubland and Desert Ecosystems Science Program

    Science.gov (United States)

    Deborah M. Finch

    2014-01-01

    In this issue of the GSD Update, we take a look back at selected studies of the Grassland, Shrubland and Desert Ecosystems Science Program (GSD) that depict its strengths and focus areas. Significant results of recent research and science delivery by GSD scientists are highlighted. We feature program research that lines up with the strategic research priorities of the...

  4. GSD Update: Year in Review: Spotlight on 2015 Research by the Grassland, Shrubland and Desert Ecosystems Science Program

    Science.gov (United States)

    Deborah. Finch

    2016-01-01

    In this issue of the GSD Update, we take a look back at selected studies of the Grassland, Shrubland and Desert Ecosystems Science Program (GSD) that depict its strengths and focus areas. Significant results of recent research and science delivery by GSD scientists are highlighted. We feature program research that lines up with the strategic research...

  5. Application of Z-Number Based Modeling in Psychological Research

    Directory of Open Access Journals (Sweden)

    Rafik Aliev

    2015-01-01

    Full Text Available Pilates exercises have been shown beneficial impact on physical, physiological, and mental characteristics of human beings. In this paper, Z-number based fuzzy approach is applied for modeling the effect of Pilates exercises on motivation, attention, anxiety, and educational achievement. The measuring of psychological parameters is performed using internationally recognized instruments: Academic Motivation Scale (AMS, Test of Attention (D2 Test, and Spielberger’s Anxiety Test completed by students. The GPA of students was used as the measure of educational achievement. Application of Z-information modeling allows us to increase precision and reliability of data processing results in the presence of uncertainty of input data created from completed questionnaires. The basic steps of Z-number based modeling with numerical solutions are presented.

  6. Application of Z-Number Based Modeling in Psychological Research.

    Science.gov (United States)

    Aliev, Rafik; Memmedova, Konul

    2015-01-01

    Pilates exercises have been shown beneficial impact on physical, physiological, and mental characteristics of human beings. In this paper, Z-number based fuzzy approach is applied for modeling the effect of Pilates exercises on motivation, attention, anxiety, and educational achievement. The measuring of psychological parameters is performed using internationally recognized instruments: Academic Motivation Scale (AMS), Test of Attention (D2 Test), and Spielberger's Anxiety Test completed by students. The GPA of students was used as the measure of educational achievement. Application of Z-information modeling allows us to increase precision and reliability of data processing results in the presence of uncertainty of input data created from completed questionnaires. The basic steps of Z-number based modeling with numerical solutions are presented.

  7. Substance Abuse among Juvenile Delinquents and Gang Members. Prevention Research Update Number Six, Spring 1990.

    Science.gov (United States)

    Pollard, John A.; Austin, Gregory A.

    There is a strong statistical correlation between delinquency activity level and the level of alcohol and other drug (AOD) use in adolescents. A strong association between drug use, drug trafficking, and youth gangs has also emerged. However, several important questions concerning the relationship of delinquency, gang membership, and AOD use…

  8. Circular Updates

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Circular Updates are periodic sequentially numbered instructions to debriefing staff and observers informing them of changes or additions to scientific and specimen...

  9. The National Shipbuilding Research Program. United States Shipbuilding Standards Master Plan Update

    National Research Council Canada - National Science Library

    1997-01-01

    .... 7. Develop a marketing strategy for the plan. 8. Adopt or convert existing global standards for domestic use. This update includes an updated survey, the SP-6 tactical plan, new windows into standards on the internet, and more.

  10. Research Update: The electronic structure of hybrid perovskite layers and their energetic alignment in devices

    Directory of Open Access Journals (Sweden)

    Selina Olthof

    2016-09-01

    Full Text Available In recent years, the interest in hybrid organic–inorganic perovskites has increased at a rapid pace due to their tremendous success in the field of thin film solar cells. This area closely ties together fundamental solid state research and device application, as it is necessary to understand the basic material properties to optimize the performances and open up new areas of application. In this regard, the energy levels and their respective alignment with adjacent charge transport layers play a crucial role. Currently, we are lacking a detailed understanding about the electronic structure and are struggling to understand what influences the alignment, how it varies, or how it can be intentionally modified. This research update aims at giving an overview over recent results regarding measurements of the electronic structure of hybrid perovskites using photoelectron spectroscopy to summarize the present status.

  11. The OMERACT MRI in Arthritis Working Group - Update on Status and Future Research Priorities

    DEFF Research Database (Denmark)

    Østergaard, Mikkel; Bird, Paul; Gandjbakhch, Frédérique

    2015-01-01

    OBJECTIVE: To provide an update on the status and future research priorities of the Outcome Measures in Rheumatology (OMERACT) magnetic resonance imaging (MRI) in arthritis working group. METHODS: A summary is provided of the activities of the group within rheumatoid arthritis (RA), psoriatic......, and at the OMERACT 12 conference, we provided longitudinal data demonstrating reliability and sensitivity to change of the RAMRIS JSN component score, supporting its use in future clinical trials. The MRI group has previously developed a PsA MRI score (PsAMRIS). At OMERACT 12, PsAMRIS was evaluated in a randomized...... reliability, but variable reliability of change scores, were reported. Potential future research areas were identified at the MRI session at OMERACT 12 including assessment of tenosynovitis in RA and enthesitis in PsA and focusing on alternative MRI techniques. CONCLUSION: MRI has been further developed...

  12. Effective Reporting. Resources in Institutional Research, Number 12.

    Science.gov (United States)

    Bers, Trudy H.

    This monograph is a guide to effective presentation of report data and information from institutional research. The work focuses on several types of presentation: the written report (alternative ways for presenting information, appearance, and the audience); graphic displays or charts (to present words or data in an organized or symbolic fashion;…

  13. Research Laboratory of Electronic Progress Report Number 135.

    Science.gov (United States)

    1993-06-01

    S.R. Bahl, and J.A. del Alamo. "Une Optoelectronique Ill-V, La Grande Motte, Etude des Niveaux Profonds dand le Transistor France, October 21-23...Chaotic Webs in Ion-orbit Chaos = 1, A = 5). Induced by Waves 2 eE° Sponsors R+wcx..- sin(kx -wt) (1) National Aeronautics and Space Administration where...Report Number 135 • Chapter 1. Plasma Dynamics where F = eEok/(mW2) is the normalized amplitude of amplitudes; second, the chaotic web exists over all

  14. The place of words and numbers in psychiatric research.

    Science.gov (United States)

    Falissard, Bruno; Révah, Anne; Yang, Suzanne; Fagot-Largeault, Anne

    2013-11-18

    In recent decades, there has been widespread debate in the human and social sciences regarding the compatibility and the relative merits of quantitative and qualitative approaches in research. In psychiatry, depending on disciplines and traditions, objects of study can be represented either in words or using two types of mathematization. In the latter case, the use of mathematics in psychiatry is most often only local, as opposed to global as in the case of classical mechanics. Relationships between these objects of study can in turn be explored in three different ways: 1/ by a hermeneutic process, 2/ using statistics, the most frequent method in psychiatric research today, 3/ using equations, i.e. using mathematical relationships that are formal and deterministic. The 3 ways of representing entities (with language, locally with mathematics or globally with mathematics) and the 3 ways of expressing the relationships between entities (using hermeneutics, statistics or equations) can be combined in a cross-tabulation, and nearly all nine combinations can be described using examples. A typology of this nature may be useful in assessing which epistemological perspectives are currently dominant in a constantly evolving field such as psychiatry, and which other perspectives still need to be developed. It also contributes to undermining the overly simplistic and counterproductive beliefs that accompany the assumption of a Manichean "quantitative/qualitative" dichotomy. Systematic examination of this set of typologies could be useful in indicating new directions for future research beyond the quantitative/qualitative divide.

  15. Sulfur technology update: selected research topics from the ASRL core research program

    Energy Technology Data Exchange (ETDEWEB)

    Clark, P. D.; Dowling, N. I.; Marriott, R.A.; Primak, A.; Davis, P.M. [Alberta Sulphur Research Ltd (Canada)

    2011-07-01

    This conference presentation is a combined effort by Alberta Sulfur Research, Ltd (ASRL) and the University of Calgary; it focuses on sulfur production technology and the ongoing research behind it. This presentation deals mainly with the use of sulfur in the oil sand industry, sulfur recovery in Claus systems, and sulfur management issues. Sulfur formation, mainly in the form of hydrogen sulfide, and the use of liquid sulfur in bitumen coking in the petrochemical industries were discussed first. This was later followed by an illustration of how sulfur recovery efficiency is greatly enhanced by catalytic tail gas incineration and improved liquid sulfur degassing technologies. A comparative scheme between the current process and the new research in utilizing sulfur in nickel metal production was also presented, showing how the new research results in less waste. In conclusion, the effects of polymeric sulfur on the strength of the solid were discussed, showing a linear relationship between the two parameters.

  16. The Oral HIV/AIDS Research Alliance: updated case definitions of oral disease endpoints.

    Science.gov (United States)

    Shiboski, C H; Patton, L L; Webster-Cyriaque, J Y; Greenspan, D; Traboulsi, R S; Ghannoum, M; Jurevic, R; Phelan, J A; Reznik, D; Greenspan, J S

    2009-07-01

    The Oral HIV/AIDS Research Alliance (OHARA) is part of the AIDS Clinical Trials Group (ACTG), the largest HIV clinical trials organization in the world. Its main objective is to investigate oral complications associated with HIV/AIDS as the epidemic is evolving, in particular, the effects of antiretrovirals on oral mucosal lesion development and associated fungal and viral pathogens. The OHARA infrastructure comprises: the Epidemiologic Research Unit (at the University of California San Francisco), the Medical Mycology Unit (at Case Western Reserve University) and the Virology/Specimen Banking Unit (at the University of North Carolina). The team includes dentists, physicians, virologists, mycologists, immunologists, epidemiologists and statisticians. Observational studies and clinical trials are being implemented at ACTG-affiliated sites in the US and resource-poor countries. Many studies have shared end-points, which include oral diseases known to be associated with HIV/AIDS measured by trained and calibrated ACTG study nurses. In preparation for future protocols, we have updated existing diagnostic criteria of the oral manifestations of HIV published in 1992 and 1993. The proposed case definitions are designed to be used in large-scale epidemiologic studies and clinical trials, in both US and resource-poor settings, where diagnoses may be made by non-dental healthcare providers. The objective of this article is to present updated case definitions for HIV-related oral diseases that will be used to measure standardized clinical end-points in OHARA studies, and that can be used by any investigator outside of OHARA/ACTG conducting clinical research that pertains to these end-points.

  17. Parameters of Time-out: Research Update and Comparison to Parenting Programs, Books, and Online Recommendations.

    Science.gov (United States)

    Corralejo, Samantha M; Jensen, Scott A; Greathouse, Ashley D; Ward, Leah E

    2018-01-01

    In reviews published more than 30 years ago, eight parameters important to the use of time-out were identified and available research was summarized. The purpose of the current paper is to provide an updated summary of existing research for each parameter of time-out. Within each parameter, we conducted a thorough review of the published literature and identified all peer-reviewed articles addressing each parameter. We identified and summarized a total of 46 articles across the eight parameters, including 32 not cited in previous reviews. Sufficient findings were available to draw conclusions regarding time-out warning, schedule of time-out, contingent versus noncontingent release, and duration. Tentative conclusions based on only a few studies could be drawn in regard to instructional versus physical administration and verbalized reason for time-out. No conclusions could be drawn regarding time-out signal and specific time-out location. While we know much more today regarding effective implementation of time-out, there is a clear need for further exploration within these identified parameters. In addition to summarizing the literature, we reviewed recommendations made by behavioral parent training programs, parenting books, and parenting Web sites, and compared how well their recommendations matched current research based on the conclusions drawn from our review. We found that parenting sources made strong and specific recommendations on several of the parameters that were either not consistent with available research or simply lacked a sufficient research base. Copyright © 2017. Published by Elsevier Ltd.

  18. GSD Update: Year in Review: Spotlight on 2017 Research by the Grassland, Shrubland and Desert Ecosystems Science Program

    Science.gov (United States)

    Deborah M. Finch

    2018-01-01

    In this issue of the GSD Update, we feature selected studies of the RMRS Grassland, Shrubland and Desert Ecosystems Science Program (GSD) that focus on the theme of fire. Significant results of recent research and science delivery by GSD scientists are highlighted. We feature program research that lines up with the strategic priorities and goals of the USDA Forest...

  19. Updated activated sludge model number 1 parameter values for improved prediction of nitrogen removal in activated sludge processes: validation at 13 full-scale plants.

    Science.gov (United States)

    Choubert, Jean-Marc; Stricker, Anne-Emmanuelle; Marquot, Aurélien; Racault, Yvan; Gillot, Sylvie; Héduit, Alain

    2009-01-01

    The Activated Sludge Model number 1 (ASM1) is the main model used in simulation projects focusing on nitrogen removal. Recent laboratory-scale studies have found that the default values given 20 years ago for the decay rate of nitrifiers and for the heterotrophic biomass yield in anoxic conditions were inadequate. To verify the relevance of the revised parameter values at full scale, a series of simulations were carried out with ASM1 using the original and updated set of parameters at 20 degrees C and 10 degrees C. The simulation results were compared with data collected at 13 full-scale nitrifying-denitrifying municipal treatment plants. This work shows that simulations using the original ASM1 default parameters tend to overpredict the nitrification rate and underpredict the denitrification rate. The updated set of parameters allows more realistic predictions over a wide range of operating conditions.

  20. FY16 ASC ATDM L2 Milestone: PARTISN Research and FleCSI Updates

    Energy Technology Data Exchange (ETDEWEB)

    Womeldorff, Geoffrey Alan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Payne, Joshua Estes [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Bergen, Benjamin Karl [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-09-01

    These are slides for a presentation on PARTISN Research and FleCSI Updates. The following topics are covered: SNAP vs PARTISN, Background Research, Production Code (structural design and changes, kernel design and implementation, lessons learned), NuT IMC Proxy, FleCSI Update (design and lessons learned). It can all be summarized in the following manner: Kokkos was shown to be effective in FY15 in implementing a C++ version of SNAP's kernel. This same methodology was applied to a production IC code, PARTISN. This was a much more complex endeavour than in FY15 for many reasons; a C++ kernel embedded in Fortran, overloading Fortran memory allocations, general language interoperability, and a fully fleshed out production code versus a simplified proxy code. Lessons learned are Legion. In no particular order: Interoperability between Fortran and C++ was really not that hard, and a useful engineering effort. Tracking down all necessary memory allocations for a kernel in a production code is pretty hard. Modifying a production code to work for more than a handful of use cases is also pretty hard. Figuring out the toolchain that will allow a successful implementation of design decisions is quite hard, if making use of "bleeding edge" design choices. In terms of performance, production code concurrency architecture can be a virtual showstopper; being too complex to easily rewrite and test in a short period of time, or depending on tool features which do not exist yet. Ultimately, while the tools used in this work were not successful in speeding up the production code, they helped to identify how work would be done, and provide requirements to tools.

  1. The Dissociative Subtype of Post-traumatic Stress Disorder: Research Update on Clinical and Neurobiological Features.

    Science.gov (United States)

    van Huijstee, Jytte; Vermetten, Eric

    2017-10-21

    Recently, a dissociative subtype of post-traumatic stress disorder (PTSD) has been included in the DSM-5. This review focuses on the clinical and neurobiological features that distinguish the dissociative subtype of PTSD from non-dissociative PTSD. Clinically, the dissociative subtype of PTSD is associated with high PTSD severity, predominance of derealization and depersonalization symptoms, a more significant history of early life trauma, and higher levels of comorbid psychiatric disorders. Furthermore, PTSD patients with dissociative symptoms exhibit different psychophysiological and neural responses to the recall of traumatic memories. While individuals with non-dissociative PTSD exhibit an increased heart rate, decreased activation of prefrontal regions, and increased activation of the amygdala in response to traumatic reminders, individuals with the dissociative subtype of PTSD show an opposite pattern. It has been proposed that dissociation is a regulatory strategy to restrain extreme arousal in PTSD through hyperinhibition of limbic regions. In this research update, promises and pitfalls in current research studies on the dissociative subtype of PTSD are listed. Inclusion of the dissociative subtype of PTSD in the DSM-5 stimulates research on the prevalence, symptomatology, and neurobiology of the dissociative subtype of PTSD and poses a challenge to improve treatment outcome in PTSD patients with dissociative symptoms.

  2. A bibliometric analysis of research updates and tendencies on steroid biotransformation

    Science.gov (United States)

    Song, Zhaoyu

    2018-03-01

    Steroid biotransformation, as a powerful tool for generation of steroid active pharmaceutical ingredients and key intermediates, has received widespread attention with increasing market demand for steroid-based drugs. In our study, a bibliometric analysis of steroid biotransformation was performed to trace the research updates and tendencies from 1993 to 2016, based on the Science Citation Index Expanded (SCIE) database. Results showed a notable growth trend in publication outputs. Although the USA was the most productive country between 1993 and 2016, developing nations, including China and India, contributed the prominent growth in recent years (2005–2016). Steroids was the leading journal in this field, and the research outputs had notably increased in the field of ‘Chemistry’, ‘Pharmacology and Pharmacy’ and ‘Biotechnology and Applied Microbiology’. Finally, research focused mainly on the efficient production of novel steroid active pharmaceutical ingredients and key intermediates through steroid biotransformation. Furthermore, cytochrome P450 involved in the side-chain oxidation of sterols has gradually become a hotspot issue in recent years.

  3. Update on Psychological Trauma, Other Severe Adverse Experiences and Eating Disorders: State of the Research and Future Research Directions.

    Science.gov (United States)

    Trottier, Kathryn; MacDonald, Danielle E

    2017-08-01

    This paper provides an updated review of the literature on the relationship between psychological trauma exposure, other severe adverse experiences, and eating disorders. Trauma exposure and other severe adverse experiences (e.g., emotional abuse) in both childhood and adulthood are associated with eating disorders. The relationship between traumatic and other adverse experiences and eating disorders appears to be mediated by emotional and behavioral dysregulation, as well as by cognitive factors such as self-criticism. Biological vulnerabilities may also be relevant to this relationship. Overall, the literature is limited by predominantly cross-sectional designs. There is clear evidence of a correlational relationship between trauma exposure and other severe adverse events, and eating disorders. Both risk and maintenance factor hypotheses have been put forth; however, prospective research testing these hypotheses remains limited. Future research should use prospective designs and focus on trauma-related symptoms (rather than trauma exposure) in order to advance research on risk and maintaining factors for eating disorders and inform treatment directions.

  4. New research on anxiety disorders in the elderly and an update on evidence-based treatments.

    Science.gov (United States)

    Andreescu, Carmen; Varon, Daniel

    2015-07-01

    Anxiety disorders are frequently encountered in the elderly, but they are largely undetected and untreated. Epidemiological studies indicate a prevalence ranging from 1.2 to 15 %. With the exception of generalized anxiety disorder and agoraphobia, which can often start in late life, most anxiety disorders in older patients are chronic and have their onset earlier in life. Anxiety disorders are an often unrecognized cause of distress, disability, and mortality risk in older adults, and they have been associated with cardiovascular disease, stroke, and cognitive decline. The mechanisms of anxiety in older adults differ from that in younger adults due to age-related neuropathology, as well as the loss and isolation so prominent in late life. Our review intends to provide a comprehensive summary of the most recent research done in the field of anxiety disorders in the elderly. Recent findings in clinical research, neuroimaging, neuroendocrinology, and neuropsychology are covered. An update on treatment options is discussed, including pharmacological and non-pharmacological alternatives.

  5. Experimental liver fibrosis research: update on animal models, legal issues and translational aspects

    Science.gov (United States)

    2013-01-01

    Liver fibrosis is defined as excessive extracellular matrix deposition and is based on complex interactions between matrix-producing hepatic stellate cells and an abundance of liver-resident and infiltrating cells. Investigation of these processes requires in vitro and in vivo experimental work in animals. However, the use of animals in translational research will be increasingly challenged, at least in countries of the European Union, because of the adoption of new animal welfare rules in 2013. These rules will create an urgent need for optimized standard operating procedures regarding animal experimentation and improved international communication in the liver fibrosis community. This review gives an update on current animal models, techniques and underlying pathomechanisms with the aim of fostering a critical discussion of the limitations and potential of up-to-date animal experimentation. We discuss potential complications in experimental liver fibrosis and provide examples of how the findings of studies in which these models are used can be translated to human disease and therapy. In this review, we want to motivate the international community to design more standardized animal models which might help to address the legally requested replacement, refinement and reduction of animals in fibrosis research. PMID:24274743

  6. Problem gambling worldwide: An update and systematic review of empirical research (2000-2015).

    Science.gov (United States)

    Calado, Filipa; Griffiths, Mark D

    2016-12-01

    Background and aims Problem gambling has been identified as an emergent public health issue, and there is a need to identify gambling trends and to regularly update worldwide gambling prevalence rates. This paper aims to review recent research on adult gambling and problem gambling (since 2000) and then, in the context of a growing liberalization of the gambling market in the European Union, intends to provide a more detailed analysis of adult gambling behavior across European countries. Methods A systematic literature search was carried out using academic databases, Internet, and governmental websites. Results Following this search and utilizing exclusion criteria, 69 studies on adult gambling prevalence were identified. These studies demonstrated that there are wide variations in past-year problem gambling rates across different countries in the world (0.12-5.8%) and in Europe (0.12-3.4%). However, it is difficult to directly compare studies due to different methodological procedures, instruments, cut-offs, and time frames. Despite the variability among instruments, some consistent results with regard to demographics were found. Discussion and conclusion The findings highlight the need for continuous monitoring of problem gambling prevalence rates in order to examine the influence of cultural context on gambling patterns, assess the effectiveness of policies on gambling-related harms, and establish priorities for future research.

  7. Problem gambling worldwide: An update and systematic review of empirical research (2000–2015)

    Science.gov (United States)

    Calado, Filipa; Griffiths, Mark D.

    2016-01-01

    Background and aims Problem gambling has been identified as an emergent public health issue, and there is a need to identify gambling trends and to regularly update worldwide gambling prevalence rates. This paper aims to review recent research on adult gambling and problem gambling (since 2000) and then, in the context of a growing liberalization of the gambling market in the European Union, intends to provide a more detailed analysis of adult gambling behavior across European countries. Methods A systematic literature search was carried out using academic databases, Internet, and governmental websites. Results Following this search and utilizing exclusion criteria, 69 studies on adult gambling prevalence were identified. These studies demonstrated that there are wide variations in past-year problem gambling rates across different countries in the world (0.12–5.8%) and in Europe (0.12–3.4%). However, it is difficult to directly compare studies due to different methodological procedures, instruments, cut-offs, and time frames. Despite the variability among instruments, some consistent results with regard to demographics were found. Discussion and conclusion The findings highlight the need for continuous monitoring of problem gambling prevalence rates in order to examine the influence of cultural context on gambling patterns, assess the effectiveness of policies on gambling-related harms, and establish priorities for future research. PMID:27784180

  8. The OMERACT MRI in Arthritis Working Group - Update on Status and Future Research Priorities.

    Science.gov (United States)

    Østergaard, Mikkel; Bird, Paul; Gandjbakhch, Frédérique; Eshed, Iris; Haugen, Ida K; Haavardsholm, Espen A; Lillegraven, Siri; Foltz, Violaine; Glinatsi, Daniel; Peterfy, Charles; Ejbjerg, Bo; Bøyesen, Pernille; Mease, Philip J; Hermann, Kay-Geert; Emery, Paul; Genant, Harry K; Conaghan, Philip G

    2015-12-01

    To provide an update on the status and future research priorities of the Outcome Measures in Rheumatology (OMERACT) magnetic resonance imaging (MRI) in arthritis working group. A summary is provided of the activities of the group within rheumatoid arthritis (RA), psoriatic arthritis (PsA), and osteoarthritis (OA), and its research priorities. The OMERACT RA MRI score (RAMRIS) evaluating bone erosion, bone edema (osteitis), and synovitis is now the standard method of quantifying articular pathology in RA trials. Cartilage loss is another important part of joint damage, and at the OMERACT 12 conference, we provided longitudinal data demonstrating reliability and sensitivity to change of the RAMRIS JSN component score, supporting its use in future clinical trials. The MRI group has previously developed a PsA MRI score (PsAMRIS). At OMERACT 12, PsAMRIS was evaluated in a randomized placebo-controlled trial of patients with PsA, demonstrating the responsiveness and discriminatory ability of applying the PsAMRIS to hands and feet. A hand OA MRI score (HOAMRIS) was introduced at OMERACT 11, and has subsequently been further validated. At OMERACT 12, good cross-sectional interreader reliability, but variable reliability of change scores, were reported. Potential future research areas were identified at the MRI session at OMERACT 12 including assessment of tenosynovitis in RA and enthesitis in PsA and focusing on alternative MRI techniques. MRI has been further developed and validated as an outcome measure in RA, PsA, and OA. The group will continue its efforts to optimize the value of MRI as a robust biomarker in rheumatology clinical trials.

  9. Medicare Part D research highlights and policy updates, 2013: impact and insights.

    Science.gov (United States)

    Stubbings, JoAnn; Lau, Denys T

    2013-04-01

    Since its implementation in 2006, Medicare Part D has evolved from a program that offered basic access to covered drugs for beneficiaries to one that has the potential to affect patient outcomes. The purpose of this article was to highlight key research findings on Medicare Part D published in 2012 and major public policy initiatives for Part D for 2013. PubMed/MEDLINE was searched for research studies on Part D published in 2012 in biomedical/scientific, peer-reviewed, English-language journals. For policy updates, sources included the Federal Register, the 2013 Final Call Letter, guidance from the Centers for Medicare and Medicaid Services, and 2012 publications on Part D policy identified in PubMed. Part D has been associated with higher medication use and lower out-of-pocket (OOP) costs of many long-term medications; however, differences within subgroups of beneficiaries have been observed. Studies on health outcomes have been inconclusive. Part D policy changes in 2013 have addressed problems with the benefit, namely coverage of benzodiazepines and barbiturates; reducing coinsurance in the coverage gap; reducing fraud, waste, and abuse; medication therapy management program standardization; and an expanded appeals process. Research continues to suggest that Part D is effective in increasing medication utilization and lowering OOP costs. Further work is needed to clarify the effects of Part D on nondrug health care service utilization and health outcomes. Policy changes for 2013 addressed specific improvements in the Medicare Part D benefit while potentially generating cost-savings for Medicare and Medicaid. Future challenges include alleviating access burden to medications during the phase-out of the coverage gap, minimizing disparities among Part D beneficiaries, and coordinating the Part D benefit with Medicare parts A and B via Medicare Accountable Care Organizations. A more integrated and coordinated Medicare benefit among all of its components would

  10. Medical Updates Number 5 to the International Space Station Probability Risk Assessment (PRA) Model Using the Integrated Medical Model

    Science.gov (United States)

    Butler, Doug; Bauman, David; Johnson-Throop, Kathy

    2011-01-01

    The Integrated Medical Model (IMM) Project has been developing a probabilistic risk assessment tool, the IMM, to help evaluate in-flight crew health needs and impacts to the mission due to medical events. This package is a follow-up to a data package provided in June 2009. The IMM currently represents 83 medical conditions and associated ISS resources required to mitigate medical events. IMM end state forecasts relevant to the ISS PRA model include evacuation (EVAC) and loss of crew life (LOCL). The current version of the IMM provides the basis for the operational version of IMM expected in the January 2011 timeframe. The objectives of this data package are: 1. To provide a preliminary understanding of medical risk data used to update the ISS PRA Model. The IMM has had limited validation and an initial characterization of maturity has been completed using NASA STD 7009 Standard for Models and Simulation. The IMM has been internally validated by IMM personnel but has not been validated by an independent body external to the IMM Project. 2. To support a continued dialogue between the ISS PRA and IMM teams. To ensure accurate data interpretation, and that IMM output format and content meets the needs of the ISS Risk Management Office and ISS PRA Model, periodic discussions are anticipated between the risk teams. 3. To help assess the differences between the current ISS PRA and IMM medical risk forecasts of EVAC and LOCL. Follow-on activities are anticipated based on the differences between the current ISS PRA medical risk data and the latest medical risk data produced by IMM.

  11. Comparative Study on Cyber Securities between Power Reactor and Research Reactor with Bayesian Update

    International Nuclear Information System (INIS)

    Shin, Jinsoo; Heo, Gyunyoung; Son, Han Seong

    2016-01-01

    The Stuxnet has shown that nuclear facilities are no more safe from cyber-attack. Due to practical experiences and concerns on increasing of digital system application, cyber security has become the important issue in nuclear industry. Korea Institute of Nuclear Nonproliferation and control (KINAC) published a regulatory standard (KINAC/RS-015) to establish cyber security framework for nuclear facilities. However, it is difficult to research about cyber security. It is hard to quantify cyber-attack which has malicious activity which is different from existing design basis accidents (DBAs). We previously proposed a methodology on development of a cyber security risk model with BBN. However, the methodology had a limitation in which the input data as prior information was solely on expert opinions. In this study, we propose a cyber security risk model for instrumentation and control (I and C) system of nuclear facilities with some equation for quantification by using Bayesian Belief Network (BBN) in order to overcome the limitation of previous research. The proposed model has been used for comparative study on cyber securities between large-sized nuclear power plants (NPPs) and small-sized Research Reactors (RR). In this study, we proposed the cyber security risk evaluation model with BBN. It includes I and C architecture, which is a target system of cyber-attack, malicious activity, which causes cyber-attack from attacker, and mitigation measure, which mitigates the cyber-attack risk. Likelihood and consequence as prior information are evaluated by considering characteristics of I and C architecture and malicious activity. The BBN model provides posterior information with Bayesian update by adding any of assumed cyber-attack scenarios as evidence. Cyber security risk for nuclear facilities is analyzed by comparing between prior information and posterior information of each node. In this study, we conducted comparative study on cyber securities between power reactor

  12. Bibliography of work on the heterogeneous photocatalytic removal of hazardous compounds from water and air: Update Number 1 to June, 1995

    Energy Technology Data Exchange (ETDEWEB)

    Blake, D.M.

    1995-11-01

    This report is an update of a bibliography, published in May, 1994, of research performed on the photocatalytic oxidation of organic or inorganic compounds in air or water and on the photocatalytic reduction of metal-containing ions in water. The general focus of the research is on removing hazardous contaminants from air water to meet environmental or health regulations. The processes covered are based on the application of heterogeneous photocatalysts. The current state-of-the-art in catalysts are forms of titanium dioxide or modifications of titanium dioxide, but work on other heterogeneous catalysts is also included in this compilation. This update contains 574 references, most published between January, 1993 and June, 1995, but some references are from earlier work that were not included in the previous report. A new section has been added which gives information about companies that are active in providing products based on photocatalytic processes or that can provide pilot, demonstration, or commercial-scale water- or air-treatment systems. Key words, assigned by the author of this report, have been included with the citations in the listing of the bibliography.

  13. An updated h-index measures both the primary and total scientific output of a researcher.

    Science.gov (United States)

    Bucur, Octavian; Almasan, Alex; Zubarev, Roman; Friedman, Mark; Nicolson, Garth L; Sumazin, Pavel; Leabu, Mircea; Nikolajczyk, Barbara S; Avram, Dorina; Kunej, Tanja; Calin, George A; Godwin, Andrew K; Adami, Hans-Olov; Zaphiropoulos, Peter G; Richardson, Des R; Schmitt-Ulms, Gerold; Westerblad, Håkan; Keniry, Megan; Grau, Georges E R; Carbonetto, Salvatore; Stan, Radu V; Popa-Wagner, Aurel; Takhar, Kasumov; Baron, Beverly W; Galardy, Paul J; Yang, Feng; Data, Dipak; Fadare, Oluwole; Yeo, Kt Jerry; Gabreanu, Georgiana R; Andrei, Stefan; Soare, Georgiana R; Nelson, Mark A; Liehn, Elisa A

    2015-01-01

    The growing interest in scientometry stems from ethical concerns related to the proper evaluation of scientific contributions of an author working in a hard science. In the absence of a consensus, institutions may use arbitrary methods for evaluating scientists for employment and promotion. There are several indices in use that attempt to establish the most appropriate and suggestive position of any scientist in the field he/she works in. A scientist's Hirsch-index (h-index) quantifies their total effective published output, but h-index summarizes the total value of their published work without regard to their contribution to each publication. Consequently, articles where the author was a primary contributor carry the same weight as articles where the author played a minor role. Thus, we propose an updated h-index named Hirsch(p,t)-index that informs about both total scientific output and output where the author played a primary role. Our measure, h(p,t) = h(p),h(t), is composed of the h-index h(t) and the h-index calculated for articles where the author was a key contributor; i.e. first/shared first or senior or corresponding author. Thus, a h(p,t) = 5,10 would mean that the author has 5 articles as first, shared first, senior or corresponding author with at least 5 citations each, and 10 total articles with at least 10 citations each. This index can be applied in biomedical disciplines and in all areas where the first and last position on an article are the most important. Although other indexes, such as r- and w-indexes, were proposed for measuring the authors output based on the position of researchers within the published articles, our simpler strategy uses the already established algorithms for h-index calculation and may be more practical to implement.

  14. Updating Photonuclear Data Library and Generating a Reference Database for Photon Strength Functions. 1st Research Coordination Meeting. Summary Report

    International Nuclear Information System (INIS)

    Goriely, S.; Dimitriou, P.

    2016-07-01

    A summary is given of the 1 st Research Coordination Meeting of the new IAEA Co-ordinated Research Project (CRP) on Updating the Photonuclear Data Library and Generating a Reference Database for Photon Strength Functions. Participants presented their work, reviewed the current status of the field with regards to measurements, theoretical models and evaluations, discussed the scope of the work to be undertaken and agreed on a list of priorities and task assignments necessary to achieve the goals of the CRP. A summary of the presentations and discussions is presented in this report. (author)

  15. Bulletin of Prosthetics Research. Rehabilitative Engineering Research and Development, Volume 18, Number 2, Fall 1981,

    Science.gov (United States)

    1981-01-01

    very heterogeneous in size and shape. Their precise assessment of this matter. chemical make-up also varies depending on whether they are of meniscal ...chemically heterogeneous. Thus, to of which are derived from the stem cells in the bone minimize the number of variables, meniscal cartilage was marrow...the certification of advanced users. 1974). lesions of the central nervous system. Instrumentation for the measurement Our method for studying motor

  16. Research of Cadastral Data Modelling and Database Updating Based on Spatio-temporal Process

    Directory of Open Access Journals (Sweden)

    ZHANG Feng

    2016-02-01

    Full Text Available The core of modern cadastre management is to renew the cadastre database and keep its currentness,topology consistency and integrity.This paper analyzed the changes and their linkage of various cadastral objects in the update process.Combined object-oriented modeling technique with spatio-temporal objects' evolution express,the paper proposed a cadastral data updating model based on the spatio-temporal process according to people's thought.Change rules based on the spatio-temporal topological relations of evolution cadastral spatio-temporal objects are drafted and further more cascade updating and history back trace of cadastral features,land use and buildings are realized.This model implemented in cadastral management system-ReGIS.Achieved cascade changes are triggered by the direct driving force or perceived external events.The system records spatio-temporal objects' evolution process to facilitate the reconstruction of history,change tracking,analysis and forecasting future changes.

  17. Contracts for field projects and supporting research on enhanced oil recovery. Progress review number 87

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-10-01

    Approximately 30 research projects are summarized in this report. Title of the project, contract number, company or university, award amount, principal investigators, objectives, and summary of technical progress are given for each project. Enhanced oil recovery projects include chemical flooding, gas displacement, and thermal recovery. Most of the research projects though are related to geoscience technology and reservoir characterization.

  18. Statistics Anxiety Update: Refining the Construct and Recommendations for a New Research Agenda.

    Science.gov (United States)

    Chew, Peter K H; Dillon, Denise B

    2014-03-01

    Appreciation of the importance of statistics literacy for citizens of a democracy has resulted in an increasing number of degree programs making statistics courses mandatory for university students. Unfortunately, empirical evidence suggests that students in nonmathematical disciplines (e.g., social sciences) regard statistics courses as the most anxiety-inducing course in their degree programs. Although a literature review exists for statistics anxiety, it was done more than a decade ago, and newer studies have since added findings for consideration. In this article, we provide a current review of the statistics anxiety literature. Specifically, related variables, definitions, and measures of statistics anxiety are reviewed with the goal of refining the statistics anxiety construct. Antecedents, effects, and interventions of statistics anxiety are also reviewed to provide recommendations for statistics instructors and for a new research agenda. © The Author(s) 2014.

  19. The factor structure of posttraumatic stress disorder: a literature update, critique of methodology, and agenda for future research.

    Science.gov (United States)

    Elhai, Jon D; Palmieri, Patrick A

    2011-08-01

    We present an update of recent literature (since 2007) exploring the factor structure of posttraumatic stress disorder (PTSD) symptom measures. Research supporting a four-factor emotional numbing model and a four-factor dysphoria model is presented, with these models fitting better than all other models examined. Variables accounting for factor structure differences are reviewed, including PTSD query instructions, type of PTSD measure, extent of trauma exposure, ethnicity, and timing of administration. Methodological and statistical limitations with recent studies are presented. Finally, a research agenda and recommendations are offered to push this research area forward, including suggestions to validate PTSD’s factors against external measures of psychopathology, test moderators of factor structure, and examine heterogeneity of symptom presentations based on factor structure examination.

  20. Update on research and application of problem-based learning in medical science education.

    Science.gov (United States)

    Fan, Chuifeng; Jiang, Biying; Shi, Xiuying; Wang, Enhua; Li, Qingchang

    2017-12-29

    Problem-based learning (PBL) is a unique form of pedagogy dedicated to developing students' self-learning and clinical practice skills. After several decades of development, although applications vary, PBL has been recognized all over the world and implemented by many medical schools. This review summarizes and updates the application and study of PBL in medical education through the literature published between 1993 and early 2017. It focuses on understanding real medical PBL courses and ways to improve PBL to achieve better learning outcomes. PBL aims to develop lifelong skills to solve practical problems rather than limiting learning to theoretical knowledge. To achieve this goal, strict and reasonable procedures need to be designed and implemented. Rigorous monitoring and timely feedback and evaluation are indispensable to constant improvements and perfecting of the process. © 2017 by The International Union of Biochemistry and Molecular Biology, 2017. © 2018 The International Union of Biochemistry and Molecular Biology.

  1. The impact of marijuana policies on youth: clinical, research, and legal update.

    Science.gov (United States)

    Ammerman, Seth; Ryan, Sheryl; Adelman, William P

    2015-03-01

    This technical report updates the 2004 American Academy of Pediatrics technical report on the legalization of marijuana. Current epidemiology of marijuana use is presented, as are definitions and biology of marijuana compounds, side effects of marijuana use, and effects of use on adolescent brain development. Issues concerning medical marijuana specifically are also addressed. Concerning legalization of marijuana, 4 different approaches in the United States are discussed: legalization of marijuana solely for medical purposes, decriminalization of recreational use of marijuana, legalization of recreational use of marijuana, and criminal prosecution of recreational (and medical) use of marijuana. These approaches are compared, and the latest available data are presented to aid in forming public policy. The effects on youth of criminal penalties for marijuana use and possession are also addressed, as are the effects or potential effects of the other 3 policy approaches on adolescent marijuana use. Recommendations are included in the accompanying policy statement. Copyright © 2015 by the American Academy of Pediatrics.

  2. Updated list of ant species (Hymenoptera, Formicidae) recorded in Santa Catarina State, southern Brazil, with a discussion of research advances and priorities

    OpenAIRE

    Ulysséa,Mônica A.; Cereto,Carlos E.; Rosumek,Félix B.; Silva,Rogério R.; Lopes,Benedito C.

    2011-01-01

    Updated list of ant species (Hymenoptera, Formicidae) recorded in Santa Catarina State, southern Brazil, with a discussion of research advances and priorities. A first working list of ant species registered in Santa Catarina State, southern Brazil was published recently. Since then, many studies with ants have been conducted in the state. With data compiled from published studies and collections in various regions of the state, we present here an updated list of 366 species (and 17 subspecies...

  3. 78 FR 4150 - Update of NIOSH Nanotechnology Strategic Plan for Research and Guidance

    Science.gov (United States)

    2013-01-18

    ... for Disease Control and Prevention (CDC) has pioneered research on the toxicological properties and characteristics of nanoparticles. This research has involved characterizing occupationally relevant nanoparticles...) applications. NIOSH is considering focusing the overarching strategic research goals for these critical areas...

  4. International topical meeting on research reactor fuel management (RRFM) - United States foreign research reactor (FRR) spent nuclear fuel (SNF) acceptance program: 2010 update

    International Nuclear Information System (INIS)

    Messick, C.E.; Taylor, J.L.; Niehus, M.T.; Landers, C.

    2010-01-01

    The Nuclear Weapons Nonproliferation Policy Concerning Foreign Research Reactor Spent Nuclear Fuel, adopted by the United States Department of Energy (DOE), in consultation with the Department of State (DOS) in May 1996, scheduled to expire May 12, 2016, to return research reactor fuel until May 12, 2019 to the U.S. is in its fourteenth year. This paper provides a brief update on the program, part of the National Nuclear Security Administration (NNSA), and discusses program initiatives and future activities. The goal of the program continues to be recovery of U.S.-origin nuclear materials, which could otherwise be used in weapons, while assisting other countries to enjoy the benefits of nuclear technology. The NNSA is seeking feedback from research reactor operators to help us understand ways to include eligible research reactors who have not yet participated in the program. (author)

  5. Obstacles to Scientific Research in Light of a Number of Variables

    Science.gov (United States)

    Algadheeb, Nourah A.; Almeqren, Monira A.

    2014-01-01

    The present study aimed to identify the scientific research obstacles facing faculty members in the College of Education at Princess Nora bint Abdul Rahman University (PNU) and to determine the differences in the obstacles according to age, academic rank, scientific specialty, marital status, number of completed studies, and time since the last…

  6. Mechanisms of change in psychotherapy for depression: An empirical update and evaluation of research aimed at identifying psychological mediators.

    Science.gov (United States)

    Lemmens, Lotte H J M; Müller, Viola N L S; Arntz, Arnoud; Huibers, Marcus J H

    2016-12-01

    We present a systematic empirical update and critical evaluation of the current status of research aimed at identifying a variety of psychological mediators in various forms of psychotherapy for depression. We summarize study characteristics and results of 35 relevant studies, and discuss the extent to which these studies meet several important requirements for mechanism research. Our review indicates that in spite of increased attention for the topic, advances in theoretical consensus about necessities for mechanism research, and sophistication of study designs, research in this field is still heterogeneous and unsatisfactory in methodological respect. Probably the biggest challenge in the field is demonstrating the causal relation between change in the mediator and change in depressive symptoms. The field would benefit from a further refinement of research methods to identify processes of therapeutic change. Recommendations for future research are discussed. However, even in the most optimal research designs, explaining psychotherapeutic change remains a challenge. Psychotherapy is a multi-dimensional phenomenon that might work through interplay of multiple mechanisms at several levels. As a result, it might be too complex to be explained in relatively simple causal models of psychological change. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Update on ongoing tank car crashworthiness research : predicted performance and fabrication approach

    Science.gov (United States)

    2008-04-22

    Research is currently underway to develop strategies for maintaining the structural integrity of railroad tank cars carrying hazardous materials during collisions. This research, sponsored by the Federal Railroad Administration (FRA), has focused on ...

  8. NHTSA's behavioral safety research: updated, annotated bibliography, 1985-2013 : traffic tech.

    Science.gov (United States)

    2014-01-01

    Through many name changes, from the Office of Program : Development and Evaluation, the Office of Research and : Evaluation, to the current Office of Behavioral Safety Research, : our focus has remained on improving the safety of drivers, : occupants...

  9. 76 FR 12361 - Request for Information: Update of NIOSH Nanotechnology Strategic Plan for Research and Guidance

    Science.gov (United States)

    2011-03-07

    ... Control and Prevention (CDC) has pioneered research on the toxicological properties and characteristics of nanoparticles. This research has involved characterizing occupationally relevant nanoparticles for predicting... explosion safety, (8) recommendations and guidance, (9) communication and information, and (10) applications...

  10. The impact of marijuana policies on youth: clinical, research, and legal update.

    Science.gov (United States)

    2015-03-01

    This policy statement is an update of the American Academy of Pediatrics policy statement "Legalization of Marijuana: Potential Impact on Youth," published in 2004. Pediatricians have special expertise in the care of children and adolescents and may be called on to advise legislators about the potential impact of changes in the legal status of marijuana on adolescents. Parents also may look to pediatricians for advice as they consider whether to support state-level initiatives that propose to legalize the use of marijuana for medical and nonmedical purposes or to decriminalize the possession of small amounts of marijuana. This policy statement provides the position of the American Academy of Pediatrics on the issue of marijuana legalization. The accompanying technical report reviews what is currently known about the relationships of marijuana use with health and the developing brain and the legal status of marijuana and adolescents' use of marijuana to better understand how change in legal status might influence the degree of marijuana use by adolescents in the future. Copyright © 2015 by the American Academy of Pediatrics.

  11. Research in Progress--Update April 1990. Occasional Paper InTER/14/90.

    Science.gov (United States)

    Boots, Maureen, Comp.

    This document contains abstracts of 29 research projects in progress in Great Britain divided into six sections: (1) the current phase of Information Technology in Education Research (InTER) programs on groupwork with computers, tools for exploratory learning, conceptual change in science, and bubble dialogue as an ethnographic research tool; (2)…

  12. The Society of Thoracic Surgeons General Thoracic Surgery Database: 2017 Update on Research.

    Science.gov (United States)

    Gaissert, Henning A; Fernandez, Felix G; Crabtree, Traves; Burfeind, William R; Allen, Mark S; Block, Mark I; Schipper, Paul H; Jacobs, Jeffrey P; Habib, Robert H; Shahian, David M

    2017-11-01

    The outcomes research efforts based on The Society of Thoracic Surgeons (STS) General Thoracic Surgery Database include two established research programs with dedicated task forces and with data analyses conducted at the STS data analytic center: (1) The STS-sponsored research by the Access and Publications program, and (2) grant and institutionally funded research by the Longitudinal Follow-Up and Linked Registries Task Force. Also, the STS recently introduced the research program enabling investigative teams to apply for access to deidentified patient-level General Thoracic Surgery Database data sets and conduct related analyses at their own institution. Last year's General Thoracic Surgery Database-based research publications and the new Participant User File research program are reviewed. Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  13. Ethical and practical guidelines for reporting genetic research results to study participants: updated guidelines from a National Heart, Lung, and Blood Institute working group.

    Science.gov (United States)

    Fabsitz, Richard R; McGuire, Amy; Sharp, Richard R; Puggal, Mona; Beskow, Laura M; Biesecker, Leslie G; Bookman, Ebony; Burke, Wylie; Burchard, Esteban Gonzalez; Church, George; Clayton, Ellen Wright; Eckfeldt, John H; Fernandez, Conrad V; Fisher, Rebecca; Fullerton, Stephanie M; Gabriel, Stacey; Gachupin, Francine; James, Cynthia; Jarvik, Gail P; Kittles, Rick; Leib, Jennifer R; O'Donnell, Christopher; O'Rourke, P Pearl; Rodriguez, Laura Lyman; Schully, Sheri D; Shuldiner, Alan R; Sze, Rebecca K F; Thakuria, Joseph V; Wolf, Susan M; Burke, Gregory L

    2010-12-01

    In January 2009, the National Heart, Lung, and Blood Institute convened a 28-member multidisciplinary Working Group to update the recommendations of a 2004 National Heart, Lung, and Blood Institute Working Group focused on Guidelines to the Return of Genetic Research Results. Changes in the genetic and societal landscape over the intervening 5 years raise multiple questions and challenges. The group noted the complex issues arising from the fact that technological and bioinformatic progress has made it possible to obtain considerable information on individuals that would not have been possible a decade ago. Although unable to reach consensus on a number of issues, the working group produced 5 recommendations. The working group offers 2 recommendations addressing the criteria necessary to determine when genetic results should and may be returned to study participants, respectively. In addition, it suggests that a time limit be established to limit the duration of obligation of investigators to return genetic research results. The group recommends the creation of a central body, or bodies, to provide guidance on when genetic research results are associated with sufficient risk and have established clinical utility to justify their return to study participants. The final recommendation urges investigators to engage the broader community when dealing with identifiable communities to advise them on the return of aggregate and individual research results. Creation of an entity charged to provide guidance to institutional review boards, investigators, research institutions, and research sponsors would provide rigorous review of available data, promote standardization of study policies regarding return of genetic research results, and enable investigators and study participants to clarify and share expectations for the handling of this increasingly valuable information with appropriate respect for the rights and needs of participants.

  14. Brain Chemistry and Behaviour: An Update on Neuroscience Research and Its Implications for Understanding Drug Addiction

    Science.gov (United States)

    Robinson, Emma S. J.

    2011-01-01

    Psychiatric disorders such as drug addiction represent one of the biggest challenges to society. This article reviews clinical and basic science research to illustrate how developments in research methodology have enabled neuroscientists to understand more about the brain mechanisms involved in addiction biology. Treating addiction represents a…

  15. Multiple sclerosis in children: an update on clinical diagnosis, therapeutic strategies, and research

    OpenAIRE

    Waldman, Amy; Ghezzi, Angelo; Bar-Or, Amit; Mikaeloff, Yann; Tardieu, Marc; Banwell, Brenda

    2014-01-01

    The clinical features, diagnostic challenges, neuroimaging appearance, therapeutic options, and pathobiological research progress in childhood—and adolescent—onset multiple sclerosis have been informed by many new insights in the past 7 years. National programmes in several countries, collaborative research efforts, and an established international paediatric multiple sclerosis study group have contributed to revised clinical diagnostic definitions, identified clinical features of multiple sc...

  16. ACL Research Retreat VI : An update on ACL injury risk and prevention

    NARCIS (Netherlands)

    R.J. Schmitz; M. Collins; D.A. Padua; Anne Benjaminse; A.M. Chaudhari; S.J. Schultz

    2012-01-01

    It has been well recognized that multiple factors, whether individually or in combination, contribute to noncontact anterior cruciate ligament (ACL) injury. The ongoing mission of the ACL Research Retreat is to bring clinicians and researchers together to present and discuss the most recent advances

  17. Update on radon-mitigation research in schools. Rept. for 1988-Aug 91

    International Nuclear Information System (INIS)

    Leovic, K.W.; Craig, A.B.; Harris, D.B.

    1991-01-01

    The paper is an overview of research by EPA's Air and Energy Engineering Research Laboratory (AEERL) on radon mitigation in 47 schools since 1988. The structural and heating, ventilating, and air-conditioning (HVAC) system characteristics of the research schools are presented, along with the mitigation techniques implemented in the schools. Research discussed includes recent and on-going projects in Colorado, Maine, Maryland, Ohio, South Dakota, Tennessee, and Virginia. Initial research focussed on the application of active subslab depressurization (ASD) to school buildings, and recent research has emphasized the ability and limitations of using HVAC systems to reduce radon levels in schools. A goal of future projects is to compare the effectiveness of the two techniques in the same building. Slab-on-grade is the most prevalent substructure in AEERL's research schools and, depending on pressure field extension, ASD systems have been recommended for radon control in many of them. In schools where they have been installed, ASD systems have performed well and are currently being evaluated for long-term performance. The distribution of HVAC system types in these schools is about a third central air handling systems, a third unit ventilators, and a third that do not supply conditioned outdoor air (i.e., fan coil units or radiant heat)

  18. An updated MILES stellar library and stellar population models (Research Note)

    NARCIS (Netherlands)

    Falcon-Barroso, J.; Sanchez-Blazquez, P.; Vazdekis, A.; Ricciardelli, E.; Cardiel, N.; Cenarro, A. J.; Gorgas, J.; Peletier, R. F.

    Aims: We present a number of improvements to the MILES library and stellar population models. We correct some small errors in the radial velocities of the stars, measure the spectral resolution of the library and models more accurately, and give a better absolute flux calibration of the models.

  19. A Good Foundation for Number Learning for Five-Year-Olds? An Evaluation of the English Early Learning "Numbers" Goal in the Light of Research

    Science.gov (United States)

    Gifford, Sue

    2014-01-01

    This article sets out to evaluate the English Early Years Foundation Stage Goal for Numbers, in relation to research evidence. The Goal, which sets out to provide "a good foundation in mathematics", has greater breadth of content and higher levels of difficulty than previous versions. Research suggests that the additional expectations…

  20. Health data research in New Zealand: updating the ethical governance framework.

    Science.gov (United States)

    Ballantyne, Angela; Style, Rochelle

    2017-10-27

    Demand for health data for secondary research is increasing, both in New Zealand and worldwide. The New Zealand government has established a large research database, the Integrated Data Infrastructure (IDI), which facilitates research, and an independent ministerial advisory group, the Data Futures Partnership (DFP), to engage with citizens, the private sector and non-government organisations (NGOs) to facilitate trusted data use and strengthen the data ecosystem in New Zealand. We commend these steps but argue that key strategies for effective health-data governance remain absent in New Zealand. In particular, we argue in favour of the establishment of: (1) a specialist Health and Disability Ethics Committee (HDEC) to review applications for secondary-use data research; (2) a public registry of approved secondary-use research projects (similar to a clinical trials registry); and (3) detailed guidelines for the review and approval of secondary-use data research. We present an ethical framework based on the values of public interest, trust and transparency to justify these innovations.

  1. The use of Theory in Family Therapy Research: Content Analysis and Update.

    Science.gov (United States)

    Chen, Ruoxi; Hughes, Alexandria C; Austin, Jason P

    2017-07-01

    In this study, we evaluated 275 empirical studies from Journal of Marital and Family Therapy and Family Process from 2010 to 2015 on their use of theory, and compared our findings to those of a similar previous analysis (Hawley & Geske, 2000). Overall, theory seems to have become much better incorporated in empirical family therapy research, with only 16.4% of the articles not using theory in either their introductory or discussion sections. Theory appeared better incorporated in the introductory sections than in the discussion sections. Systems theory remained the most commonly used conceptual framework, followed by attachment theory. We discuss areas for improving theory incorporation in family therapy research, and offer suggestions for both family therapy researchers and educators. © 2017 American Association for Marriage and Family Therapy.

  2. The European society of gynaecological oncology: update on objectives and educational and research activities.

    Science.gov (United States)

    Brantnerova, Renata; Manchanda, Ranjit; Colombo, Nicoletta

    2012-01-01

    The European Society of Gynaecological Oncology (ESGO) is the principal European society contributing to the study, prevention, and treatment of gynecologic cancers. Founded in 1983, ESGO has more than 1,300 members in more than 40 European countries and worldwide who benefit from ESGO's innovative education and research initiatives and networking opportunities. ESGO objectives have been recently identified through a strategic planning process and include education, care, research, collaboration, awareness, and sustainability. As a leading gynecologic oncology society, ESGO holds biennial meetings where experts meet to discuss latest advances in gynecologic treatment and care. The 17(th) International Meeting of ESGO (ESGO 17) proved to be a resounding success, with 2,700 delegates and speakers who gathered from around the world in the cultured city of Milan, Italy. The structure of the congress included keynote lectures, debates, state-of-the art sessions, and focused sunrise sessions, together with oral and poster presentations and satellite symposia sponsored by pharmaceutical companies. For the first time, during ESGO 17 the Society organized a seminar for European patient groups with an interest in gynecologic cancers with the aim of facilitating different patientrelated activities across Europe. Moreover, The European Network of Young Gynaecologic Oncologists (ENYGO), the European Network of Gynaecologic Oncology Trial Groups (ENGOT), and the European Network of Translational Research in Gynaecological Oncology (ENTRIGO) had their own section during ESGO 17. ESGO also holds numerous workshops throughout the calendar year and provides clinical and research grants, online educational materials, webcasts, and numerous networking opportunities.

  3. Updating AP Potential™ Expectancy Tables Involving PSAT/NMSQT® Writing. Research Notes. RN-35

    Science.gov (United States)

    Ewing, Maureen; Camara, Wayne J.; Millsap, Roger E.; Milewski, Glenn B.

    2007-01-01

    AP Potential™ is a data-driven tool offered by the College Board that uses scores from the PSAT/NMSQT® to identify students who have the potential to succeed in Advanced Placement Program® (AP®) courses (College Board, 2007). Research showing a moderate-to-strong correlation between PSAT/NMSQT scores and AP Exam scores serves as the basis for this…

  4. A Free-Response Method of Computer Assisted Personality Assessment: A Research Update.

    Science.gov (United States)

    1987-07-08

    primacy tween "irrelevancies" and "intermedi- or recency effects would prove interes- ates." ting. For research purposes, it is help- Unfortunately, such a...fact is seen to fall midway on recency effect also is possible, where a given dimension, then its score is later-mentioned self-descriptors weigh

  5. Head and Spinal Cord Trauma Involving Youth Recreational Activities. Research Update.

    Science.gov (United States)

    McAleese, Willis J.; Scantling, Ed

    1996-01-01

    Summarizes what current research on head and spinal cord injuries sustained during participation in recreation has to offer practitioners in terms of awareness and possible preventive strategies. It noted that by addressing injury prevention through the health-belief model paradigm, recreation practitioners move a step beyond simply providing…

  6. Global foot-and-mouth disease research update and gap analysis: 2 - epidemiology, wildlife and economics

    Science.gov (United States)

    In 2014, the Global Foot-and-mouth disease Research ings in the fields of (i) epidemiology, (ii) wildlife and (iii) Alliance (GFRA) conducted a gap analysis of foot-and- economics. Although the three sections, epidemiology, wildlife and economics are presented as separate entities, the fields are ...

  7. HIGHLIGHTS OF THE RUSSIAN HEALTH STUDIES PROGRAM AND UPDATED RESEARCH FINDINGS.

    Science.gov (United States)

    Fountos, Barrett N

    2017-04-01

    Recognized for conducting cutting-edge science in the field of radiation health effects research, the Department of Energy's (DOE) Russian Health Studies Program has continued to generate excitement and enthusiasm throughout its 23-year mission to assess worker and public health risks from radiation exposure resulting from nuclear weapons production activities in the former Soviet Union. The three goals of the Program are to: (1) clarify the relationship between health effects and chronic, low-to-medium dose radiation exposure; (2) estimate the cancer risks from exposure to gamma, neutron, and alpha radiation; and (3) provide information to the national and international organizations that determine radiation protection standards and practices. Research sponsored by DOE's Russian Health Studies Program is conducted under the authority of the Joint Coordinating Committee for Radiation Effects Research (JCCRER), a bi-national committee representing Federal agencies in the United States and the Russian Federation. Signed in 1994, the JCCRER Agreement established the legal basis for the collaborative research between USA and Russian scientists to determine the risks associated with working at or living near Russian former nuclear weapons production sites. The products of the Program are peer-reviewed publications on cancer risk estimates from worker and community exposure to ionizing radiation following the production of nuclear weapons in Russia. The scientific return on investment has been substantial. Through 31 December 2015, JCCRER researchers have published 299 peer-reviewed publications. To date, the research has focused on the Mayak Production Association (Mayak) in Ozersk, Russia, which is the site of the first Soviet nuclear weapons production facility, and people in surrounding communities along the Techa River. There are five current projects in the Russian Health Studies Program: two radiation epidemiology studies; two historical dose reconstruction

  8. Highlights of the Russian health studies program and updated research findings

    International Nuclear Information System (INIS)

    Fountos, Barrett N.

    2017-01-01

    Recognized for conducting cutting-edge science in the field of radiation health effects research, the Department of Energy's (DOE) Russian Health Studies Program has continued to generate excitement and enthusiasm throughout its 23-year mission to assess worker and public health risks from radiation exposure resulting from nuclear weapons production activities in the former Soviet Union. The three goals of the Program are to: (1) clarify the relationship between health effects and chronic, low-to-medium dose radiation exposure; (2) estimate the cancer risks from exposure to gamma, neutron, and alpha radiation; and (3) provide information to the national and international organizations that determine radiation protection standards and practices. Research sponsored by DOE's Russian Health Studies Program is conducted under the authority of the Joint Coordinating Committee for Radiation Effects Research (JCCRER), a bi-national committee representing Federal agencies in the United States and the Russian Federation. Signed in 1994, the JCCRER Agreement established the legal basis for the collaborative research between USA and Russian scientists to determine the risks associated with working at or living near Russian former nuclear weapons production sites. The products of the Program are peer-reviewed publications on cancer risk estimates from worker and community exposure to ionizing radiation following the production of nuclear weapons in Russia. The scientific return on investment has been substantial. Through 31 December 2015, JCCRER researchers have published 299 peer-reviewed publications. To date, the research has focused on the Mayak Production Association (Mayak) in Ozersk, Russia, which is the site of the first Soviet nuclear weapons production facility, and people in surrounding communities along the Techa River. There are five current projects in the Russian Health Studies Program: two radiation epidemiology studies; two historical dose

  9. The value of TOP2A gene copy number variation as a biomarker in breast cancer: Update of DBCG trial 89D

    DEFF Research Database (Denmark)

    Nielsen, K.V.; Ejlertsen, B.; Moller, S.

    2008-01-01

    BACKGROUND: Previous analyses of TOP2A and HER2 in the Danish Breast Cancer Coopererative Group (DBCG) trial 89D suggested that TOP2A amplifications and possible also deletions are predictive markers for the effect of adjuvant epirubicin in patients with primary breast cancer. We present an updated...... and extended statistical analysis, requested for IVD-labeling of TOP2A testing. MATERIAL AND METHODS: In the DBCG trial 89D 980 Danish patients were randomly assigned to nine cycles of intravenous CMF (cyclophosphamide, methotrexate, and fluorouracil) or CEF (cyclophosphamide, epirubicin, and fluorouracil......, favoring CEF among patients with TOP2A aberrations was found for RFS (p=0.02 for interaction) but not for OS (p=0.14 for interaction). CONCLUSION: In conclusion, this updated analysis of TOP2A aberrations in DBCG trial 89D suggests a differential benefit of adjuvant chemotherapy in patients with primary...

  10. Substance Use in Lesbian, Gay, and Bisexual Populations: An Update on Empirical Research and Implications for Treatment

    Science.gov (United States)

    Green, Kelly E.; Feinstein, Brian A.

    2011-01-01

    Historically, substance use problems were thought to be more prevalent in lesbian, gay, and bisexual (LGB) populations, and correcting skewed perceptions about substance abuse among LGB individuals is critically important. This review provides an update on empirical evidence on LGB substance use patterns and treatment outcome, with specific focus on clinical implications of findings. Compared to earlier studies, the recent research included in this review has used more sophisticated methodologies, more representative samples, and also has investigated multiple dimensions of sexual orientation in relation to substance use patterns. Findings from recent research suggest that lesbians and bisexual women are at greater risk for alcohol and drug use disorders and related problems, and that gay and bisexual men are at greater risk for illicit drug use and related problems. Several sociocultural factors have emerged as correlates of substance use patterns in LGB populations (e.g., affiliation with gay culture, HIV-status), and several demographic characteristics (e.g., female, older age) do not appear to be as robust of protective factors against substance abuse for LGB individuals compared to heterosexual populations. Bisexual identity and/or behavior in particular seem to be related to increased risk for substance abuse. In terms of treatment outcome, limitations of extant research prevent conclusions about the relative impact of LGB-specific interventions, and further research that includes women and uses more equivalent comparison interventions is needed. Clinical implications of research findings are discussed for case identification, selection of treatment goals (e.g., moderation versus abstinence), targets for intervention, and specific treatment modalities. PMID:22061339

  11. malERA: An updated research agenda for malaria elimination and eradication.

    Directory of Open Access Journals (Sweden)

    Regina N Rabinovich

    2017-11-01

    Full Text Available Achieving a malaria-free world presents exciting scientific challenges as well as overwhelming health, equity, and economic benefits. WHO and countries are setting ambitious goals for reducing the burden and eliminating malaria through the "Global Technical Strategy" and 21 countries are aiming to eliminate malaria by 2020. The commitment to achieve these targets should be celebrated. However, the need for innovation to achieve these goals, sustain elimination, and free the world of malaria is greater than ever. Over 180 experts across multiple disciplines are engaged in the Malaria Eradication Research Agenda (malERA Refresh process to address problems that need to be solved. The result is a research and development agenda to accelerate malaria elimination and, in the longer term, transform the malaria community's ability to eradicate it globally.

  12. canSAR: an updated cancer research and drug discovery knowledgebase.

    Science.gov (United States)

    Tym, Joseph E; Mitsopoulos, Costas; Coker, Elizabeth A; Razaz, Parisa; Schierz, Amanda C; Antolin, Albert A; Al-Lazikani, Bissan

    2016-01-04

    canSAR (http://cansar.icr.ac.uk) is a publicly available, multidisciplinary, cancer-focused knowledgebase developed to support cancer translational research and drug discovery. canSAR integrates genomic, protein, pharmacological, drug and chemical data with structural biology, protein networks and druggability data. canSAR is widely used to rapidly access information and help interpret experimental data in a translational and drug discovery context. Here we describe major enhancements to canSAR including new data, improved search and browsing capabilities, new disease and cancer cell line summaries and new and enhanced batch analysis tools. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  13. Research ethics in the era of personalized medicine: updating science's contract with society.

    Science.gov (United States)

    Meslin, Eric M; Cho, Mildred K

    2010-01-01

    With the completed sequence of the human genome has come the prospect of substantially improving the quality of life for millions through personalized medicine approaches. Still, any advances in this direction require research involving human subjects. For decades science and ethics have enjoyed an allegiance reflected in a common set of ethical principles and procedures guiding the conduct of research with human subjects. Some of these principles emphasize avoiding harm over maximizing benefit. In this paper we revisit the priority given to these ethical principles - particularly the principles that support a cautious approach to science - and propose a reframing of the 'social contract' between science and society that emphasizes reciprocity and meeting public needs.

  14. malERA: An updated research agenda for malaria elimination and eradication.

    Science.gov (United States)

    Rabinovich, Regina N; Drakeley, Chris; Djimde, Abdoulaye A; Hall, B Fenton; Hay, Simon I; Hemingway, Janet; Kaslow, David C; Noor, Abdisalan; Okumu, Fredros; Steketee, Richard; Tanner, Marcel; Wells, Timothy N C; Whittaker, Maxine A; Winzeler, Elizabeth A; Wirth, Dyann F; Whitfield, Kate; Alonso, Pedro L

    2017-11-01

    Achieving a malaria-free world presents exciting scientific challenges as well as overwhelming health, equity, and economic benefits. WHO and countries are setting ambitious goals for reducing the burden and eliminating malaria through the "Global Technical Strategy" and 21 countries are aiming to eliminate malaria by 2020. The commitment to achieve these targets should be celebrated. However, the need for innovation to achieve these goals, sustain elimination, and free the world of malaria is greater than ever. Over 180 experts across multiple disciplines are engaged in the Malaria Eradication Research Agenda (malERA) Refresh process to address problems that need to be solved. The result is a research and development agenda to accelerate malaria elimination and, in the longer term, transform the malaria community's ability to eradicate it globally.

  15. What's new in the literature: an update of new research since the original WHS diabetic foot ulcer guidelines in 2006.

    Science.gov (United States)

    Braun, Liza; Kim, Paul J; Margolis, David; Peters, Edgar J; Lavery, Lawrence A

    2014-01-01

    The objective of the paper was to update the diabetic foot ulcer guidelines that were previously published in 2006. We performed a key word search using MEDLINE and Cochrane reviews for publication between January 2006 and January 2012. Articles that fit the inclusion criteria were reviewed and the previous guidelines were updated. © 2014 by the Wound Healing Society.

  16. Update on research and future directions of the OMERACT MRI inflammatory arthritis group

    DEFF Research Database (Denmark)

    Conaghan, Philip G; McQueen, Fiona M; Bird, Paul

    2011-01-01

    of this score will require more PsA imaging datasets. As well, due to improved image resolution since the development of the original rheumatoid arthritis MRI scoring system (RAMRIS), the Task Force has worked on semiquantitative assessment of joint space narrowing, and developed a reliable method...... as a potential RAMRIS addendum, although responsiveness will need to be evaluated. One of the strengths of MRI is the ability to detect subclinical synovitis, so the group worked on obtaining low disease activity/clinical remission datasets from a number of international centers and presented cross......The OMERACT Magnetic Resonance Imaging (MRI) Task Force has developed and evolved the psoriatic arthritis MRI score (PsAMRIS) over the last few years, and at OMERACT 10, presented longitudinal evaluation by multiple readers, using PsA datasets obtained from extremity MRI magnets. Further evaluation...

  17. Update of X- and γ-ray decay data standards for detector calibration and other applications. Summary report of the 1. research co-ordination meeting

    International Nuclear Information System (INIS)

    Herman, M.; Nichols, A.

    1999-07-01

    The discussions and conclusions of the First Research Co-ordination Meeting to Update X- and γ-ray Decay Data Standards for Detector Calibration are described in this summary report. The agreed list of radionuclides to be evaluated is given, along with the evaluation procedures and assignment of tasks among participants of the CRP. 14 presentations given at the meeting were indexed separately

  18. Recent Advances in Sarcopenia Research in Asia: 2016 Update From the Asian Working Group for Sarcopenia.

    Science.gov (United States)

    Chen, Liang-Kung; Lee, Wei-Ju; Peng, Li-Ning; Liu, Li-Kuo; Arai, Hidenori; Akishita, Masahiro

    2016-08-01

    Sarcopenia was recently classified a geriatric syndrome and is a major challenge to healthy aging. Affected patients tend to have worse clinical outcomes and higher mortality than those without sarcopenia. Although there is general agreement on the principal diagnostic characteristics, initial thresholds for muscle mass, strength, and physical performance were based on data from populations of predominantly Europid ancestry and may not apply worldwide. The Asian Working Group for Sarcopenia (AWGS) issued regional consensus guidelines in 2014, and many more research studies from Asia have since been published; this review summarizes recent progress. The prevalence of sarcopenia estimated by the AWGS criteria ranges between 4.1% and 11.5% of the general older population; however, prevalence rates were higher in Asian studies that used European Working Group on Sarcopenia in Older People cut-offs. Risk factors include age, sex, heart disease, hyperlipidemia, daily alcohol consumption, and low protein or vitamin intake; physical activity is protective. Adjusting skeletal muscle mass by weight rather than height is better in showing the effect of older age in sarcopenia and identifying sarcopenic obesity; however, some Asian studies found no significant skeletal muscle loss, and muscle strength might be a better indicator. Although AWGS 2014 diagnostic cut-offs were generally well accepted, some may require further revision in light of conflicting evidence from some studies. The importance of sarcopenia in diverse therapeutic areas is increasingly evident, with strong research interest in sarcopenic obesity and the setting of malignancy. Pharmacologic interventions have been unsatisfactory, and the core management strategies remain physical exercise and nutritional supplementation; however, further research is required to determine the most beneficial approaches. Copyright © 2016 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc

  19. The Large Synoptic Survey Telescope: A summary update on the scientific potential for pulsating star research

    Science.gov (United States)

    Graham, Melissa L.

    2017-09-01

    The Large Synoptic Survey Telescope (LSST) will provide hundreds of deep images of the southern sky over its 10 year duration, enabling variability studies for an unprecedentedly large and unbiased population of objects. In this proceeding paper I will cover the aspects of the LSST's survey and data products that are most relevant to the study of stellar pulsations (Sect. 1), and provide a directory of pertinent materials for further information. I will also summarize the anticipated variable star sample sizes from the LSST, and highlight recent research from several members of the scientific community which evaluates the scientific potential of the LSST's data products with respect to pulsating stars (Sect. 2).

  20. Research Update: Materials design of implantable nanogenerators for biomechanical energy harvesting

    Science.gov (United States)

    Li, Jun; Wang, Xudong

    2017-07-01

    Implantable nanogenerators are rapidly advanced recently as a promising concept for harvesting biomechanical energy in vivo. This review article presents an overview of the most current progress of implantable piezoelectric nanogenerator (PENG) and triboelectric nanogenerator (TENG) with a focus on materials selection, engineering, and assembly. The evolution of the PENG materials is discussed from ZnO nanostructures, to high-performance ferroelectric perovskites, to flexible piezoelectric polymer mesostructures. Discussion of TENGs is focused on the materials and surface features of friction layers, encapsulation materials, and device integrations. Challenges faced by this promising technology and possible future research directions are also discussed.

  1. Seed Biology Updates - Highlights and New Discoveries in Seed Dormancy and Germination Research.

    Science.gov (United States)

    Nonogaki, Hiroyuki

    2017-01-01

    An understanding of the biology of seeds has been greatly advanced in recent years. The progresses, particularly in the field of seed dormancy and germination research, have been made at a remarkable speed. Some of the possible epigenetic mechanisms, including an involvement of non-coding RNA, which were predicted for DELAY OF GERMINATION1 just a few years ago, have now been demonstrated with strong molecular and genetic evidence. Imprinting, or parent-of-origin-specific gene silencing/expression, which was characterized particularly for developing seeds, was also found in imbibed seeds and suggested for dormancy mechanisms. Hormone biology in seeds, which is the most advanced and almost a traditional area of seed research, also presents a new dimension. Upstream regulators of hormone metabolism and hormone transporters, such as abscisic acid and gibberellin influx/efflux carriers, have been identified. Characterization of the novel posttranslational modification pathways, including the N-end rule and S -nitrosylation pathways, which play a critical role in turnover of the major hormone signal transduction proteins, also expanded our knowledge about the complexity of hormone signaling in seeds. These progresses made at the molecular level are significant steps toward a better understanding of how seeds translate soil and other environmental signals into their internal hormone biology and make an important decision to stay dormant or commence with germination.

  2. An Update to Space Biomedical Research: Tissue Engineering in Microgravity Bioreactors

    Directory of Open Access Journals (Sweden)

    Abolfazl Barzegari

    2012-03-01

    Full Text Available Introduction: The severe need for constructing replacement tissues in organ transplantation has necessitated the development of tissue engineering approaches and bioreactors that can bring these approaches to reality. The inherent limitations of conventional bioreactors in generating realistic tissue constructs led to the devise of the microgravity tissue engineering that uses Rotating Wall Vessel (RWV bioreactors initially developed by NASA. Methods: In this review article, we intend to highlight some major advances and accomplishments in the rapidly-growing field of tissue engineering that could not be achieved without using microgravity. Results: Research is now focused on assembly of 3 dimensional (3D tissue fragments from various cell types in human body such as chondrocytes, osteoblasts, embryonic and mesenchymal stem cells, hepatocytes and pancreas islet cells. Hepatocytes cultured under microgravity are now being used in extracorporeal bioartificial liver devices. Tissue constructs can be used not only in organ replacement therapy, but also in pharmaco-toxicology and food safety assessment. 3D models of various cancers may be used in studying cancer development and biology or in high-throughput screening of anticancer drug candidates. Finally, 3D heterogeneous assemblies from cancer/immune cells provide models for immunotherapy of cancer. Conclusion: Tissue engineering in (simulated microgravity has been one of the stunning impacts of space research on biomedical sciences and their applications on earth.

  3. Multiple sclerosis in children: an update on clinical diagnosis, therapeutic strategies, and research.

    Science.gov (United States)

    Waldman, Amy; Ghezzi, Angelo; Bar-Or, Amit; Mikaeloff, Yann; Tardieu, Marc; Banwell, Brenda

    2014-09-01

    The clinical features, diagnostic challenges, neuroimaging appearance, therapeutic options, and pathobiological research progress in childhood-and adolescent-onset multiple sclerosis have been informed by many new insights in the past 7 years. National programmes in several countries, collaborative research efforts, and an established international paediatric multiple sclerosis study group have contributed to revised clinical diagnostic definitions, identified clinical features of multiple sclerosis that differ by age of onset, and made recommendations regarding the treatment of paediatric multiple sclerosis. The relative risks conveyed by genetic and environmental factors to paediatric multiple sclerosis have been the subject of several large cohort studies. MRI features have been characterised in terms of qualitative descriptions of lesion distribution and applicability of MRI aspects to multiple sclerosis diagnostic criteria, and quantitative studies have assessed total lesion burden and the effect of the disease on global and regional brain volume. Humoral-based and cell-based assays have identified antibodies against myelin, potassium-channel proteins, and T-cell profiles that support an adult-like T-cell repertoire and cellular reactivity against myelin in paediatric patients with multiple sclerosis. Finally, the safety and efficacy of standard first-line therapies in paediatric multiple sclerosis populations are now appreciated in more detail, and consensus views on the future conduct and feasibility of phase 3 trials for new drugs have been proposed. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. Nuclear power and the public: an update of collected survey research on nuclear power

    International Nuclear Information System (INIS)

    Rankin, W.L.; Melber, B.D.; Overcast, T.D.; Nealey, S.M.

    1981-12-01

    The purpose of this research was to collect, analyze, and summarize all of the nuclear power-related surveys conducted in the United States through June 1981, that we could obtain. The surveys collected were national, statewide, and areawide in scope. Slightly over 100 surveys were collected for an earlier, similar effort carried out in 1977. About 130 new surveys were added to the earlier survey data. Thus, about 230 surveys were screened for inclusion in this report. Because of space limitations, national surveys were used most frequently in this report, followed distantly by state surveys. In drawing our conclusions about public beliefs and attitudes toward nuclear power, we placed most of our confidence in survey questions that were used by national polling firms at several points in time. A summary of the research findings is presented, beginning with general attitudes toward nuclear power, followed by a summary of beliefs and attitudes about nuclear power issues, and ended by a summary of beliefs and attitudes regarding more general energy issues

  5. Multiple sclerosis in children: an update on clinical diagnosis, therapeutic strategies, and research

    Science.gov (United States)

    Waldman, Amy; Ghezzi, Angelo; Bar-Or, Amit; Mikaeloff, Yann; Tardieu, Marc; Banwell, Brenda

    2015-01-01

    The clinical features, diagnostic challenges, neuroimaging appearance, therapeutic options, and pathobiological research progress in childhood—and adolescent—onset multiple sclerosis have been informed by many new insights in the past 7 years. National programmes in several countries, collaborative research efforts, and an established international paediatric multiple sclerosis study group have contributed to revised clinical diagnostic definitions, identified clinical features of multiple sclerosis that differ by age of onset, and made recommendations regarding the treatment of paediatric multiple sclerosis. The relative risks conveyed by genetic and environmental factors to paediatric multiple sclerosis have been the subject of several large cohort studies. MRI features have been characterised in terms of qualitative descriptions of lesion distribution and applicability of MRI aspects to multiple sclerosis diagnostic criteria, and quantitative studies have assessed total lesion burden and the effect of the disease on global and regional brain volume. Humoral-based and cell-based assays have identified antibodies against myelin, potassium-channel proteins, and T-cell profiles that support an adult-like T-cell repertoire and cellular reactivity against myelin in paediatric patients with multiple sclerosis. Finally, the safety and efficacy of standard first-line therapies in paediatric multiple sclerosis populations are now appreciated in more detail, and consensus views on the future conduct and feasibility of phase 3 trials for new drugs have been proposed. PMID:25142460

  6. Nuclear power and the public: an update of collected survey research on nuclear power

    Energy Technology Data Exchange (ETDEWEB)

    Rankin, W.L.; Melber, B.D.; Overcast, T.D.; Nealey, S.M.

    1981-12-01

    The purpose of this research was to collect, analyze, and summarize all of the nuclear power-related surveys conducted in the United States through June 1981, that we could obtain. The surveys collected were national, statewide, and areawide in scope. Slightly over 100 surveys were collected for an earlier, similar effort carried out in 1977. About 130 new surveys were added to the earlier survey data. Thus, about 230 surveys were screened for inclusion in this report. Because of space limitations, national surveys were used most frequently in this report, followed distantly by state surveys. In drawing our conclusions about public beliefs and attitudes toward nuclear power, we placed most of our confidence in survey questions that were used by national polling firms at several points in time. A summary of the research findings is presented, beginning with general attitudes toward nuclear power, followed by a summary of beliefs and attitudes about nuclear power issues, and ended by a summary of beliefs and attitudes regarding more general energy issues.

  7. Research on animal cloning technologies and their implications in medical ethics: an update.

    Science.gov (United States)

    Revel, M

    2000-01-01

    Reproduction by cloning has been achieved by transfer into enucleated oocytes of nuclei from embryonic cells and more recently from cells of adult animals. The efficiency at which embryos produced by such nuclear transfers will develop into healthy newborns is very low but has allowed to produce some cloned bovines, bovines and mice. Since the first report of sheep cloning from an adult cell in 1997, the potential applications of reproductive cloning in human medicine have been envisaged amidst a flurry of moral debates. Although the technology is still far from being ready for any human use, it has been condemned from the outset. It has also led to irrational fantasies and fears mainly based on the misconception that genetic identity means identical twin personalities. Scientific research is ongoing on refining the cloning technology for applications in the production of genetically homogeneous farm animals with useful nutritional or therapeutic genetic traits. A new area of research is non-reproductive therapeutic cloning for the purpose of producing autologous embryonic cells and tissues for transplantation.

  8. Research Update: Mechanical properties of metal-organic frameworks – Influence of structure and chemical bonding

    Directory of Open Access Journals (Sweden)

    Wei Li

    2014-12-01

    Full Text Available Metal-organic frameworks (MOFs, a young family of functional materials, have been attracting considerable attention from the chemistry, materials science, and physics communities. In the light of their potential applications in industry and technology, the fundamental mechanical properties of MOFs, which are of critical importance for manufacturing, processing, and performance, need to be addressed and understood. It has been widely accepted that the framework topology, which describes the overall connectivity pattern of the MOF building units, is of vital importance for the mechanical properties. However, recent advances in the area of MOF mechanics reveal that chemistry plays a major role as well. From the viewpoint of materials science, a deep understanding of the influence of chemical effects on MOF mechanics is not only highly desirable for the development of novel functional materials with targeted mechanical response, but also for a better understanding of important properties such as structural flexibility and framework breathing. The present work discusses the intrinsic connection between chemical effects and the mechanical behavior of MOFs through a number of prototypical examples.

  9. Update on Extended Operation of Stirling Convertors in Thermal Vacuum at NASA Glenn Research Center

    Science.gov (United States)

    Oriti, Salvatore M.

    2006-01-01

    The U.S. Department of Energy (DOE), Lockheed Martin Space Systems (LMSS), Infinia Corporation, and NASA Glenn Research Center (GRC) have been developing a Stirling Radioisotope Generator (SRG) for use as a power system on space science missions. This generator would make use of Stirling cycle energy conversion to achieve higher efficiency than currently used alternatives. A test has been initiated at GRC to demonstrate functionality of Stirling conversion in a thermal vacuum environment over an extended period of time. The test article resembles the configuration of the SRG, but was designed without the requirement of low mass. Throughout the 8700 cumulative hours of operation, modifications to the supporting hardware were required to attain the desired operating conditions. These modifications, the status of testing, and the data recorded will be discussed in this paper.

  10. Malaria Vaccine Adjuvants: Latest Update and Challenges in Preclinical and Clinical Research

    Directory of Open Access Journals (Sweden)

    Elena Mata

    2013-01-01

    Full Text Available There is no malaria vaccine currently available, and the most advanced candidate has recently reported a modest 30% efficacy against clinical malaria. Although many efforts have been dedicated to achieve this goal, the research was mainly directed to identify antigenic targets. Nevertheless, the latest progresses on understanding how immune system works and the data recovered from vaccination studies have conferred to the vaccine formulation its deserved relevance. Additionally to the antigen nature, the manner in which it is presented (delivery adjuvants as well as the immunostimulatory effect of the formulation components (immunostimulants modulates the immune response elicited. Protective immunity against malaria requires the induction of humoral, antibody-dependent cellular inhibition (ADCI and effector and memory cell responses. This review summarizes the status of adjuvants that have been or are being employed in the malaria vaccine development, focusing on the pharmaceutical and immunological aspects, as well as on their immunization outcomings at clinical and preclinical stages.

  11. Malaria vaccine adjuvants: latest update and challenges in preclinical and clinical research.

    Science.gov (United States)

    Mata, Elena; Salvador, Aiala; Igartua, Manoli; Hernández, Rosa María; Pedraz, José Luis

    2013-01-01

    There is no malaria vaccine currently available, and the most advanced candidate has recently reported a modest 30% efficacy against clinical malaria. Although many efforts have been dedicated to achieve this goal, the research was mainly directed to identify antigenic targets. Nevertheless, the latest progresses on understanding how immune system works and the data recovered from vaccination studies have conferred to the vaccine formulation its deserved relevance. Additionally to the antigen nature, the manner in which it is presented (delivery adjuvants) as well as the immunostimulatory effect of the formulation components (immunostimulants) modulates the immune response elicited. Protective immunity against malaria requires the induction of humoral, antibody-dependent cellular inhibition (ADCI) and effector and memory cell responses. This review summarizes the status of adjuvants that have been or are being employed in the malaria vaccine development, focusing on the pharmaceutical and immunological aspects, as well as on their immunization outcomings at clinical and preclinical stages.

  12. The Large Synoptic Survey Telescope: A summary update on the scientific potential for pulsating star research

    Directory of Open Access Journals (Sweden)

    Graham Melissa L.

    2017-01-01

    Full Text Available The Large Synoptic Survey Telescope (LSST will provide hundreds of deep images of the southern sky over its 10 year duration, enabling variability studies for an unprecedentedly large and unbiased population of objects. In this proceeding paper I will cover the aspects of the LSST’s survey and data products that are most relevant to the study of stellar pulsations (Sect. 1, and provide a directory of pertinent materials for further information. I will also summarize the anticipated variable star sample sizes from the LSST, and highlight recent research from several members of the scientific community which evaluates the scientific potential of the LSST’s data products with respect to pulsating stars (Sect. 2.

  13. Ophthalmic applications of lipid-based drug nanocarriers: an update of research and patenting activity.

    Science.gov (United States)

    Pignatello, Rosario; Carbone, Claudia; Puglia, Carmelo; Offerta, Alessia; Bonina, Francesco P; Puglisi, Giovanni

    2015-01-01

    Ophthalmic diseases collect great attention by researchers and pharmaceutical technologists, since they can dramatically worsen the quality of life. Because of the limited duration of action on the eye surface, and anatomical/physiological barriers to drug penetration from it into the inner eye structures, conventional ocular formulations are generally unable to perform at their best. Nanotechnology approaches can represent a solution to improve the therapeutic efficiency, compliance and safety of ocular drugs. In this respect, lipid-based nanocarriers are among the most interesting systems. Their composition and production methods make them highly biocompatible and safe formulations. This review illustrates the developments achieved in ocular drug delivery using lipid-based nanocarriers, with a critical revision of recent scientific articles and filed patents.

  14. A comprehensive review on food waste anaerobic digestion: Research updates and tendencies.

    Science.gov (United States)

    Ren, Yuanyuan; Yu, Miao; Wu, Chuanfu; Wang, Qunhui; Gao, Ming; Huang, Qiqi; Liu, Yu

    2018-01-01

    Anaerobic digestion has been practically applied in agricultural and industrial waste treatment and recognized as an economical-effective way for food waste disposal. This paper presented an overview on the researches about anaerobic digestion of food waste. Technologies (e.g., pretreatment, co-digestion, inhibition and mitigation, anaerobic digestion systems, etc.) were introduced and evaluated on the basis of bibliometric analysis. Results indicated that ethanol and aerobic prefermentation were novel approaches to enhance substrates hydrolysis and methane yield. With the promotion of resource recovery, more attention should be paid to biorefinery technologies which can produce more useful products toward zero emissions. Furthermore, a technological route for food waste conversion based on anaerobic digestion was proposed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Update on Advances in Research on Idiosyncratic Drug-Induced Liver Injury.

    Science.gov (United States)

    Kim, Seung Hyun; Naisbitt, Dean J

    2016-01-01

    Drug-induced liver injury (DILI) is a major concern for public health, as well as for drug development in the pharmaceutical industry, since it can cause liver failure and lead to drug withdrawal from the market and black box warnings. Thus, it is important to identify biomarkers for early prediction to increase our understanding of mechanisms underlying DILI that will ultimately aid in the exploration of novel therapeutic strategies to prevent or manage DILI. DILI can be subdivided into 'intrinsic' and 'idiosyncratic' categories, although the validity of this classification remains controversial. Idiosyncratic DILI occurs in a minority of susceptible individuals with a prolonged latency, while intrinsic DILI results from drug-induced direct hepatotoxicity over the course of a few days. The rare occurrence of idiosyncratic DILI requires multicenter collaborative investigations and phenotype standardization. Recent progress in research on idiosyncratic DILI is based on key developments in 3 areas: (1) newly developed high-throughput genotyping across the whole genome allowing for the identification of genetic susceptibility markers, (2) new mechanistic concepts on the pathogenesis of DILI revealing a key role of drug-responsive T lymphocytes in the immunological response, and (3) broad multidisciplinary approaches using different platform "-omics" technologies that have identified novel biomarkers for the prediction of DILI. An association of a specific human leukocyte antigen (HLA) allele with DILI has been reported for several drugs. HLA-restricted T-cell immune responses have also been investigated using lymphocytes and T-cell clones isolated from patients. A microRNA, miR-122, has been discovered as a promising biomarker for the early prediction of DILI. In this review, we summarize recent advances in research on idiosyncratic DILI with an understanding of the key role of adaptive immune systems.

  16. Pharmacotherapy for opioid dependence in jails and prisons: research review update and future directions

    Directory of Open Access Journals (Sweden)

    Sharma A

    2016-04-01

    Full Text Available Anjalee Sharma,1 Kevin E O'Grady,1,2 Sharon M Kelly,1 Jan Gryczynski,1 Shannon Gwin Mitchell,1 Robert P Schwartz1 1Friends Research Institute, Baltimore, 2Department of Psychology, University of Maryland, College Park, MD, USA Purpose: The World Health Organization recommends the initiation of opioid agonists prior to release from incarceration to prevent relapse or overdose. Many countries in the world employ these strategies. This paper considers the evidence to support these recommendations and the factors that have slowed their adoption in the US. Methods: We reviewed randomized controlled trials (RCTs and longitudinal/observational studies that examine participant outcomes associated with the initiation or continuation of opioid agonists (methadone, buprenorphine or antagonists (naltrexone during incarceration. Papers were identified through a literature search of PubMed with an examination of their references and were included if they reported outcomes for methadone, buprenorphine, or naltrexone continued during incarceration or initiated prior to release in a correctional institution. Results: Fourteen studies were identified, including eight RCTs and six observational studies. One RCT found that patients treated with methadone who were continued on versus tapered off methadone during brief incarceration were more likely to return to treatment upon release. A second RCT found that the group starting methadone treatment in prison versus a waiting list was less likely to report using heroin and sharing syringes during incarceration. A third RCT found no differences in postrelease heroin use or reincarceration between individuals initiating treatment with methadone versus those initiating treatment with buprenorphine during relatively brief incarcerations. Findings from four additional RCTs indicate that starting opioid agonist treatment during incarceration versus after release was associated with higher rates of entry into community

  17. The South/Southeast Asia Research Initiative (SARI) Update and Meeting Objectives

    Science.gov (United States)

    Vadrevu, Krishna Prasad

    2017-01-01

    Land Use/Cover Change (LU/CC) is one of the most important types of environmental change in South and Southeast Asian countries. Several studies suggest that LU/CC in these countries is in large part driven by population growth and economic development. In the region, changes that are most common include urban expansion, agricultural land loss, land abandonment, deforestation, logging, reforestation, etc. To address the research needs and priorities in the region, a regional initiative entitled South Southeast Asia Regional Initiative (SARI) has been developed involving US and regional scientists. The initiative is funded by NASA Land Cover, Land Use Change program. The goal of SARI is to integrate state-of-the-art remote sensing, natural sciences, engineering and social sciences to enrich LU/CC science in South Southeast Asian countries. In the presentation, LU/CC change research in SARI countries will be highlighted including the drivers of change. For example, in South Asia, forest cover has been increasing in countries like India, Nepal and Bhutan due to sustainable afforestation measures; whereas, large-scale deforestation in Southeast Asian countries is still continuing, due to oil palm plantation expansion driven by the international market demand in Malaysia and Indonesia. With respect to urbanization, South and Southeast Asian countries contain 23 megacities, each with more than 10 million people. Rapid urbanization is driving agricultural land loss and agricultural intensification has been increasing due to less availability of land for growing food crops such as in India, Vietnam, and Thailand. The drivers of LUCC vary widely in the region and include such factors as land tenure, local economic development, government policies, inappropriate land management, land speculation, improved road networks, etc. In addition, variability in the weather, climate, and socioeconomic factors also drive LU/CC resulting in disruptions of biogeochemical cycles

  18. Updates on chemical and biological research on botanical ingredients in dietary supplements.

    Science.gov (United States)

    Pawar, Rahul S; Tamta, Hemlata; Ma, Jun; Krynitsky, Alexander J; Grundel, Erich; Wamer, Wayne G; Rader, Jeanne I

    2013-05-01

    Increased use of dietary supplements is a phenomenon observed worldwide. In the USA, more than 40% of the population recently reported using complementary and alternative medicines, including botanical dietary supplements. Perceptions that such dietary supplements are natural and safe, may prevent disease, may replace prescription medicines, or may make up for a poor diet, play important roles in their increased use. Toxicity of botanical dietary supplements may result from the presence of naturally occurring toxic constituents or from contamination or adulteration with pharmaceutical agents, heavy metals, mycotoxins, pesticides, or bacteria, misidentification of a plant species in a product, formation of electrophilic metabolites, organ-specific reactions, or botanical-drug interactions. The topics discussed in this review illustrate several issues in recent research on botanical ingredients in dietary supplements. These include (1) whether 1,3-dimethylamylamine is a natural constituent of rose geranium (Pelargonium graveolens), (2) how analysis of the components of dietary supplements containing bitter melon (Momordica charantia) is essential to understanding their potential biological effects, and (3) how evolving methods for in vitro studies on botanical ingredients can contribute to safety evaluations. The virtual explosion in the use of botanical ingredients in hundreds of products presents a considerable challenge to the analytical community, and the need for appropriate methods cannot be overstated. We review recent developments and use of newer and increasingly sensitive methods that can contribute to increasing the safety and quality of botanical ingredients in dietary supplements.

  19. Research Update: Electrical monitoring of cysts using organic electrochemical transistors a

    Science.gov (United States)

    Huerta, M.; Rivnay, J.; Ramuz, M.; Hama, A.; Owens, R. M.

    2015-03-01

    Organotypic three-dimensional (3D) cell culture models have the potential to act as surrogate tissues in vitro, both for basic research and for drug discovery/toxicology. 3D cultures maintain not only 3D architecture but also cell-cell and cell extracellular matrix interactions, particularly when grown in cysts or spheroids. Characterization of cell cultures grown in 3D formats, however, provides a significant challenge for cell biologists due to the incompatibility of these structures with commonly found optical or electronic monitoring systems. Electronic impedance spectroscopy is a cell culture monitoring technique with great potential; however, it has not been possible to integrate 3D cultures with commercially available systems to date. Cyst-like 3D cultures are particularly challenging due to their small size and difficulty in manipulation. Herein, we demonstrate isolation of cyst-like 3D cultures by capillarity and subsequent integration with the organic electrochemical transistor for monitoring the integrity of these structures. We show not only that this versatile device can be adapted to the cyst format for measuring resistance and, therefore, the quality of the cysts, but also can be used for quantitative monitoring of the effect of toxic compounds on cells in a 3D format. The ability to quantitatively predict effects of drugs on 3D cultures in vitro has large future potential for the fields of drug discovery and toxicology.

  20. Pharmacotherapy for opioid dependence in jails and prisons: research review update and future directions.

    Science.gov (United States)

    Sharma, Anjalee; O'Grady, Kevin E; Kelly, Sharon M; Gryczynski, Jan; Mitchell, Shannon Gwin; Schwartz, Robert P

    2016-01-01

    and relatively widespread in Europe are discussed. Recommendations for future research are outlined.

  1. Dietary interventions in children with autism spectrum disorders - an updated review of the research evidence.

    Science.gov (United States)

    Marti, Luis F

    2014-01-01

    Autism Spectrum Disorders (ASD) is a group of life-long neurodevelopmental disorders, with onset before 3 years of age. They are characterized by qualitative impairmentin social interactions, absent or impaired language and communication skills, and present with a wide range of stereotyped, repetitive behaviors. Function and outcome are affected not only by core deficits but by associated behaviors such as hyperactivity, aggression, anxiety, and depression. Increasing evidence indicates that autism is a complex, multifactorial disorder involving the brain and the body, a result of genetic vulnerabilities interacting with environmental factors. Although genetics plays a role, the fact, that the incidence of autism in identical twins is not 100% points to external or environmental factors as contributors. No etiology - based treatment has yet been developed. During the last two decades many educational, psychosocial and pharmacological interventions had been utilized and claimed to be effective and even "curative". The word treatment should be used with caution, and should stand for interventions that are aimed to help people with ASD to adjust more effectively to their environment. Many studies have indicated that behavioral therapy and medication may be at least partially helpful in the treatment of children with ASD particularly on the symptoms of aggression, hyperactivity and attention. In the light of an approved and well established treatment for ASD, over the past two decades research on the effect of diet and nutrition on autism has been increasing. Particular attention has focused on the role of food additives, refined sugar, food allergies, and fatty acid metabolism. However, the results are conflicting and not conclusive. We present here anupdated review summarizing the potentials and limits of the most frequent nutritional and dietary interventions in the treatment of Autism Spectrum Disorders.

  2. Neuropathic pain: an updated grading system for research and clinical practice

    Science.gov (United States)

    Finnerup, Nanna B.; Haroutounian, Simon; Kamerman, Peter; Baron, Ralf; Bennett, David L.H.; Bouhassira, Didier; Cruccu, Giorgio; Freeman, Roy; Hansson, Per; Nurmikko, Turo; Raja, Srinivasa N.; Rice, Andrew S.C.; Serra, Jordi; Smith, Blair H.; Treede, Rolf-Detlef; Jensen, Troels S.

    2016-01-01

    Abstract The redefinition of neuropathic pain as “pain arising as a direct consequence of a lesion or disease affecting the somatosensory system,” which was suggested by the International Association for the Study of Pain (IASP) Special Interest Group on Neuropathic Pain (NeuPSIG) in 2008, has been widely accepted. In contrast, the proposed grading system of possible, probable, and definite neuropathic pain from 2008 has been used to a lesser extent. Here, we report a citation analysis of the original NeuPSIG grading paper of 2008, followed by an analysis of its use by an expert panel and recommendations for an improved grading system. As of February, 2015, 608 eligible articles in Scopus cited the paper, 414 of which cited the neuropathic pain definition. Of 220 clinical studies citing the paper, 56 had used the grading system. The percentage using the grading system increased from 5% in 2009 to 30% in 2014. Obstacles to a wider use of the grading system were identified, including (1) questions about the relative significance of confirmatory tests, (2) the role of screening tools, and (3) uncertainties about what is considered a neuroanatomically plausible pain distribution. Here, we present a revised grading system with an adjusted order, better reflecting clinical practice, improvements in the specifications, and a word of caution that even the “definite” level of neuropathic pain does not always indicate causality. In addition, we add a table illustrating the area of pain and sensory abnormalities in common neuropathic pain conditions and propose areas for further research. PMID:27115670

  3. Net Zero Water Update

    Science.gov (United States)

    2011-05-12

    Update 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7...Opened to Collect Supplemental Data from Candidate Installations 15 Mar 11 Supplemental Data received from Army Commands 16-31 Mar 11 DOE...hierarchy (reduction, re-purpose, recycling & composting , energy recovery, and disposal) • Complied with Net Zero definitions • Demonstrated

  4. Determination of the minimum number of fuel elements of the RP-10 research reactor

    International Nuclear Information System (INIS)

    Languasco, J.

    1989-01-01

    The peruvian research reactor RP-10 is composed of a compound nucleus of boxes containing fuel plates which are cooled with light water in order to remove heat produced by fission of uranium atoms. However from a certainty viewpoint, it exists certain restrictions to design the cooling system. The most admissible caloric flux of 90.3 watts/cm 2 is deflux of 90.3 watts/cm 2 is determined on the basis of these thermic restrictions when cooling speed is 409 cm/sec permitting at least 24 fuel elements(boxes) within the nucleus. On the basis of restrictions of load loss in the nucleus, it would be permitted at least 18 fuel elements, but this quantity breaks thermic restrictions for this reason, 24 boxes in the nucleus will be the minimum number of elements

  5. Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee.

    Science.gov (United States)

    Rossini, P M; Burke, D; Chen, R; Cohen, L G; Daskalakis, Z; Di Iorio, R; Di Lazzaro, V; Ferreri, F; Fitzgerald, P B; George, M S; Hallett, M; Lefaucheur, J P; Langguth, B; Matsumoto, H; Miniussi, C; Nitsche, M A; Pascual-Leone, A; Paulus, W; Rossi, S; Rothwell, J C; Siebner, H R; Ugawa, Y; Walsh, V; Ziemann, U

    2015-06-01

    These guidelines provide an up-date of previous IFCN report on "Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application" (Rossini et al., 1994). A new Committee, composed of international experts, some of whom were in the panel of the 1994 "Report", was selected to produce a current state-of-the-art review of non-invasive stimulation both for clinical application and research in neuroscience. Since 1994, the international scientific community has seen a rapid increase in non-invasive brain stimulation in studying cognition, brain-behavior relationship and pathophysiology of various neurologic and psychiatric disorders. New paradigms of stimulation and new techniques have been developed. Furthermore, a large number of studies and clinical trials have demonstrated potential therapeutic applications of non-invasive brain stimulation, especially for TMS. Recent guidelines can be found in the literature covering specific aspects of non-invasive brain stimulation, such as safety (Rossi et al., 2009), methodology (Groppa et al., 2012) and therapeutic applications (Lefaucheur et al., 2014). This up-dated review covers theoretical, physiological and practical aspects of non-invasive stimulation of brain, spinal cord, nerve roots and peripheral nerves in the light of more updated knowledge, and include some recent extensions and developments. Copyright © 2015 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  6. Bibliography of work on the heterogeneous photocatalytic removal of hazardous compounds from water and air, Update Number 2 to October 1996

    Energy Technology Data Exchange (ETDEWEB)

    Blake, D.M.

    1997-01-01

    The Solar Industrial Program has developed processes that destroy hazardous substances in or remove them from water and air. The processes of interest in this report are based on the application of heterogeneous photocatalysts, principally titanium dioxide or modifications thereof, but work on other heterogeneous catalysts is included in this compilation. This report continues bibliographies that were published in May, 1994, and October, 1995. The previous reports included 663 and 574 citations, respectively. This update contains an additional 518 references. These were published during the period from June 1995 to October 1996, or are references from prior years that were not included in the previous reports. The work generally focuses on removing hazardous contaminants from air or water to meet environmental or health regulations. This report also references work on properties of semiconductor photocatalysts and applications of photocatalytic chemistry in organic synthesis. This report follows the same organization as the previous publications. The first part provides citations for work done in a few broad categories that are generic to the process. Three tables provide references to work on specific substances. The first table lists organic compounds that are included in various lists of hazardous substances identified by the US Environmental Protection Agency (EPA). The second table lists compounds not included in those categories, but which have been treated in a photocatalytic process. The third table covers inorganic compounds that are on EPA lists of hazardous materials or that have been treated by a photocatalytic process. A short update on companies that are active in providing products or services based on photocatalytic processes is provided.

  7. MEK Inhibitors Research Update

    Science.gov (United States)

    Drugs that block the MEK protein have shown promise in several cancers. Trametinib has had encouraging results in patients with advanced melanoma, and selumetinib has been tested in patients with advanced thyroid and ovarian cancers.

  8. Cookstove Research Update

    Science.gov (United States)

    This webinar includes the following topics: (1) Introduction and field activities, John Mitchell, (2) STAR (Science To Achieve Results) grants, Terry Keating, (3) LCA (life cycle assessment) report, (4) Mutagenicity study, David DeMarini, (5) Health effects study, Jan Dye, (6) IS...

  9. Research of causes of low IPO number in the Czech Republic

    Directory of Open Access Journals (Sweden)

    Tomáš Meluzín

    2008-01-01

    Full Text Available Funding development of the company through the “Initial Public Offering” has a high representation globally, the Czech Republic unlike, and belongs to traditional methods of raising funds necessary for development of business in the developed capital markets. In the United States of America, Japan and in the Western Europe countries the method of company funding through IPO has been ap­p­lying for several decades already. The first public stock offerings began to be applied in these markets in higher volumes from the beginning of the 60th of the last century. From that period importance of IPO goes up globally and the initial public stock offerings begin to be applied more and more even in the Central and Eastern European countries. Under the conditions of the Czech capital market this way funding of development of the company, connected with its entering into the capital market, is not very usual. The Strategy of Sustainable Development of the Czech Republic considers this situation the weakness of the Czech economy, and its resolving has to be paid a due care. The present paper introduces the results of an analysis identifying the causes of the low numbers of IPOs in the Czech Republic. These causes were analyzed in a comprehensive way covering the period of time from the beginnings of the modern-day capital market in the Czech Republic until the present times. In order to reach the objective, the secondary research of the literature sources, focused on the issue in question and the primary research in the Czech companies was carried out.

  10. Update of X- and γ-ray decay data standards for detector calibration and other applications. Summary report of the second research co-ordination meeting

    International Nuclear Information System (INIS)

    Herman, M.; Nichols, A.L.

    2000-09-01

    The Second Research Co-ordination Meeting to Update X- and γ-ray Decay Data Standards for Detector Calibration was held at PTB Braunschweig from 10 to 12 May 2000. A primary aim of this meeting was to review progress in the evaluation and recommendation of data under the auspices of the CRP. All CRP activities were reviewed, and actions agreed for the remaining 18 months of the programme. Separate indexing was provided for 13 contributions to the meeting

  11. Atmospheric Renewable Energy Research, Volume 4: Atmospheric Renewable Energy Field Study Number 2 (ARE2)

    Science.gov (United States)

    2017-10-30

    ARL-TR-8198 ● Oct 2017 US Army Research Laboratory Atmospheric Renewable Energy Research, Volume 4: Atmospheric Renewable Energy ...originator. ARL-TR-8198 ● Oct 2017 US Army Research Laboratory Atmospheric Renewable Energy Research, Volume 4: Atmospheric Renewable... Energy Field Study #2 (ARE2) by Gail Vaucher and Sean D’Arcy Computational and Information Sciences Directorate, ARL Jenna Forrester Advanced

  12. Current Practice in Research Ethics: Global Trends and New Opportunities for African Universities. Research and Innovation Policy Series. Number 1

    Science.gov (United States)

    Roberts, Liam

    2007-01-01

    Research Ethics has emerged as one of the most well-developed policy areas within the sphere of Research and Innovation Management. As such, for African institutions looking to strengthen their policy frameworks, develop increased collaborations, and increase research outputs, a thorough understanding of global trends in Ethics will be vital.…

  13. Mass Media in Society: The Need of Research. Reports and Papers on Mass Communication, Number 59.

    Science.gov (United States)

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    More and better research should be undertaken, nationally and internationally, on the effect of mass media upon society. Prior to such research, there needs to be an awareness of the realities of society today and of broadcasting structure. There should also be an understanding of the research that has already been done and of the gaps in that…

  14. Exploratory graph analysis: A new approach for estimating the number of dimensions in psychological research.

    Science.gov (United States)

    Golino, Hudson F; Epskamp, Sacha

    2017-01-01

    The estimation of the correct number of dimensions is a long-standing problem in psychometrics. Several methods have been proposed, such as parallel analysis (PA), Kaiser-Guttman's eigenvalue-greater-than-one rule, multiple average partial procedure (MAP), the maximum-likelihood approaches that use fit indexes as BIC and EBIC and the less used and studied approach called very simple structure (VSS). In the present paper a new approach to estimate the number of dimensions will be introduced and compared via simulation to the traditional techniques pointed above. The approach proposed in the current paper is called exploratory graph analysis (EGA), since it is based on the graphical lasso with the regularization parameter specified using EBIC. The number of dimensions is verified using the walktrap, a random walk algorithm used to identify communities in networks. In total, 32,000 data sets were simulated to fit known factor structures, with the data sets varying across different criteria: number of factors (2 and 4), number of items (5 and 10), sample size (100, 500, 1000 and 5000) and correlation between factors (orthogonal, .20, .50 and .70), resulting in 64 different conditions. For each condition, 500 data sets were simulated using lavaan. The result shows that the EGA performs comparable to parallel analysis, EBIC, eBIC and to Kaiser-Guttman rule in a number of situations, especially when the number of factors was two. However, EGA was the only technique able to correctly estimate the number of dimensions in the four-factor structure when the correlation between factors were .7, showing an accuracy of 100% for a sample size of 5,000 observations. Finally, the EGA was used to estimate the number of factors in a real dataset, in order to compare its performance with the other six techniques tested in the simulation study.

  15. Defense Acquisition Research Journal. Volume 20, Number 1, Issue 65, April 2013

    Science.gov (United States)

    2013-04-01

    Mary C. Redshaw Deputy Executive Editor ISSN 2156-8391 (print) ISSN 2156-8405 (online) The Defense Acquisition Research Journal , formerly the Defense...Fort Belvoir, VA, and at additional U.S. Postal facilities. Postmaster, send address changes to: Editor, Defense Acquisition Research Journal , DAU...Robert Wirthlin Air Force Institute of Technology Dr. Roy Wood Defense Acquisition University The Defense Acquisition Research Journal (ARJ) is a

  16. About the necessity to update the Radiological safety and protection regulations of the National Institute of Nuclear Research (ININ)

    International Nuclear Information System (INIS)

    Alvarez R, J.T.

    1997-01-01

    It is argued the necessity to update the Radiological safety and Protection regulations (Review 3) of ININ, with the purpose that it implements the ICRU operative magnitudes system. Such a system used with radiological protection purposes. The objective of this system is to do an estimation of the effective equivalent dose H E and/or the Effective dose E, proposed in the ICRP 26 and ICRU 60 dose limits systems respectively. (Author)

  17. Choosing important health outcomes for comparative effectiveness research: An updated systematic review and involvement of low and middle income countries

    Science.gov (United States)

    Davis, Katherine; Gorst, Sarah L.; Harman, Nicola; Smith, Valerie; Gargon, Elizabeth; Altman, Douglas G.; Blazeby, Jane M.; Clarke, Mike; Tunis, Sean; Williamson, Paula R.

    2018-01-01

    Background Core outcome sets (COS) comprise a minimum set of outcomes that should be measured and reported in all trials for a specific health condition. The COMET (Core Outcome Measures in Effectiveness Trials) Initiative maintains an up to date, publicly accessible online database of published and ongoing COS. An annual systematic review update is an important part of this process. Methods This review employed the same, multifaceted approach that was used in the original review and the previous two updates. This approach has identified studies that sought to determine which outcomes/domains to measure in clinical trials of a specific condition. This update includes an analysis of the inclusion of participants from low and middle income countries (LMICs) as identified by the OECD, in these COS. Results Eighteen publications, relating to 15 new studies describing the development of 15 COS, were eligible for inclusion in the review. Results show an increase in the use of mixed methods, including Delphi surveys. Clinical experts remain the most common stakeholder group involved. Overall, only 16% of the 259 COS studies published up to the end of 2016 have included participants from LMICs. Conclusion This review highlights opportunities for greater public participation in COS development and the involvement of stakeholders from a wider range of geographical settings, in particular LMICs. PMID:29438429

  18. Report on the inaugural meeting of the international consortium on hallucination research : a clinical and research update and 16 consensus-set goals for future research

    NARCIS (Netherlands)

    Waters, F.; Aleman, A.; Fernyhough, C.; Allen, P.

    This article presents a report on the first meeting of the International Consortium on Hallucination Research, which took place on September 13-14, 2011 at the Institute of Psychiatry, London. The first day of the meeting served to reflect on the current state of knowledge regarding auditory

  19. Childhood Obesity and Nutrition Issues in the United States: An Update on School-based Policies and Practices. Education Policy Brief, Volume 10, Number 1, Spring 2012

    Science.gov (United States)

    Spradlin, Terry; Gard, Greta; Huang, Vivian; Kopp, Beth; Malik, Alanna

    2012-01-01

    This Education Policy Brief examines the latest research and statistics regarding childhood obesity. In addition to providing an overview of current trends and effects of childhood obesity, this brief considers the reasons for the increase in obesity rates among children, as well as the latest federal and state initiatives created to combat…

  20. Levels of Achievement: A Review of the Assessment of Practice. Researching Professional Education. Research Reports Series Number 5.

    Science.gov (United States)

    Gerrish, Kate; McManus, Mike; Ashworth, Peter

    Assessment of practice at diploma, degree, and postgraduate levels in nursing and midwifery education in Britain was the focus of a research study. Key issues from a critical review of literature on the assessment of theory and practice at different academic levels were as follows: lack of clarity in defining "levels"; inconsistencies in…

  1. Impact of GDP, spending on R&D, number of universities and scientific journals on research publications among Asian countries.

    Science.gov (United States)

    Meo, Sultan Ayoub; Al Masri, Abeer A; Usmani, Adnan Mahmood; Memon, Almas Naeem; Zaidi, Syed Ziauddin

    2013-01-01

    This study aimed to compare the impact of Gross Domestic Product (GDP) per capita, spending on Research and Development (R&D), number of universities, and Indexed Scientific Journals on total number of research documents (papers), citations per document and Hirsch index (H-index) in various science and social science subjects among Asian countries. In this study, 40 Asian countries were included. The information regarding Asian countries, their GDP per capita, spending on R&D, total number of universities and indexed scientific journals were collected. We recorded the bibliometric indicators, including total number of research documents, citations per document and H-index in various science and social sciences subjects during the period 1996-2011. The main sources for information were World Bank, SCI-mago/Scopus and Web of Science; Thomson Reuters. The mean per capita GDP for all the Asian countries is 14448.31±2854.40 US$, yearly per capita spending on R&D 0.64±0.16 US$, number of universities 72.37±18.32 and mean number of ISI indexed journal per country is 17.97±7.35. The mean of research documents published in various science and social science subjects among all the Asian countries during the period 1996-2011 is 158086.92±69204.09; citations per document 8.67±0.48; and H-index 122.8±19.21. Spending on R&D, number of universities and indexed journals have a positive correlation with number of published documents, citations per document and H-index in various science and social science subjects. However, there was no association between the per capita GDP and research outcomes. The Asian countries who spend more on R&D have a large number of universities and scientific indexed journals produced more in research outcomes including total number of research publication, citations per documents and H-index in various science and social science subjects.

  2. Number of Bovine Animals in Provinces Incoming Working Field GAP International Agricultural Research and Training Center

    Directory of Open Access Journals (Sweden)

    Yavuz Han

    2014-05-01

    Full Text Available In this review, the share in total and the presence of cattle in provinces of GAPUTAEM has been referred. According to official data of 2012 of TUIK, when number of cattle was 11.972.923 heads in 1991, in 2012 years increased 13.914.912 heads. According to year of 1991, number of cattle increased 16%. In our country, the number of Anatolian Water Buffalo declined from 366.150 heads to 107.435 heads during 1991-2012 and this reduction is 70.6%. 15.977.838 tons milk was obtained from dairy cattle of 5.431.400 heads and average milk yield was 2.942 kg/head. 46.989 tons milk was produced from 46.959 heads of Anatolian Water Buffaloes and average milk yield was 1.006 kg/head. However, there were totally cattle of 1.173.008 heads in study field of Institute. 1.098.895 tons milk was produced from cattle of 451.039 heads. Totally, there were 15.478 heads Anatolian Water Buffaloes in 11 provinces. 6.384 tons milk was produced from 6.738 heads Anatolian Water Buffaloes in 2012. Across the country, despite cattle (domestic decreased, cattle (cross-bred and cattle (culture had increased. The possibility of breeding of native cattle should be investigated. Also, growers and technical staffs should be trained that affected by entering of culture breeds.

  3. Vitex agnus castus essential oil and menopausal balance: a research update [Complementary Therapies in Nursing and Midwifery 8 (2003) 148-154].

    Science.gov (United States)

    Chopin Lucks, Barbara

    2003-08-01

    The first trial of two essential oils (derived separately from leaf and fruit) of Vitex agnus castus for menopausal balance was conducted in the summer of 2000 by the author. Surveys completed by the 23 participants in that trial indicated strong symptomatic relief of common menopausal symptoms.(2) This research update details the result of the second round of trials, which were conducted in the summer of 2002 with 52 additional subjects under the supervision of 12 diverse health practitioners. The second trial appears to support the finding of the first trial, as well as identifying some important contraindications to use of the essential oil.

  4. Report on the consultants' meeting on preparation of the proposal for a coordinated research project to update X- and γ-ray decay data standards for detector calibration

    International Nuclear Information System (INIS)

    Nichols, A.; Herman, M.

    1998-05-01

    The IAEA Nuclear Data Section has been charged by the International Nuclear Data Committee to consider the establishment of a Coordinated Research Project (CRP) to update the IAEA database of X-ray and γ-ray Standards for Detector Calibration. This CRP should re-define the radionuclides most suited for detector calibration, extending applications to safeguards, materials analysis, environmental monitoring, and medical use. This document is a report on the Consultants' Meeting held at IAEA, Vienna, between 24-25 November 1997 to assess the current needs, re-define the most suitable radionuclides, and advise the IAEA Nuclear Data Section on the need and form of such a CRP

  5. School Climate Research Summary: August 2012. School Climate Brief, Number 3

    Science.gov (United States)

    Thapa, Amrit; Cohen, Jonathan; Higgins-D'Alessandro, Ann; Guffey, Shawn

    2012-01-01

    Over the past three decades, researchers and educators have increasingly recognized the importance of K-12 school climate. This summary report builds on previous school climate reviews and details how school climate is associated with and/or promotes safety, healthy relationships, engaged learning and teaching and school improvement efforts. In…

  6. Scenarios as Research Tools for Investigating Social Issues. Studies in Educational Administration Number 45.

    Science.gov (United States)

    Small, Marlene B.; Briggs, Dora K.

    This paper describes an experiment in using the "scenario," a concept parallel to that of the case study, as a research tool for obtaining information about possible sex discrimination in personnel decisions by high school principals in South Australia. A review of the literature indicated that in spite of legislation aimed at…

  7. Framing Internships from an Employers' Perspective: Length, Number, and Relevancy. CERI Research Brief 6-2013

    Science.gov (United States)

    Gardner, Phil

    2013-01-01

    Over the past decade internships have become an essential talent management strategy for organizations big and small. The Collegiate Employment Research Institute (CERI) has tracked the role of internships, finding that internships have eclipsed on-­campus interviewing in bringing organizations to college campuses…

  8. Program Solicitation Number 86.1, Small Business Innovation Research Program.

    Science.gov (United States)

    1986-01-31

    field care after traumatic injury when evacuation is delayed. The overall aim of this research and development is to-provide treatment under adverse...allowed deployment times ranging from hundreds of seconds for exo-atmospheric deployments down to seconds for endo-atmospheric deployments ( Starburst

  9. Battelle Research Outlook, Volume 2 Number 3. Cleaning Up the Atmosphere.

    Science.gov (United States)

    Westerman, Arthur B., Ed.

    "Outlook" publications focus on areas of science and technology in which research can be valuable to industry, government, and society as a whole. This issue deals with the problems of air pullution and air quality control. The first of six essays,". . . This Most Excellent Canopy, the Air," prognosticates the surge in atmospheric pollution and…

  10. Update of European bioethics

    DEFF Research Database (Denmark)

    Rendtorff, Jacob Dahl

    2015-01-01

    This paper presents an update of the research on European bioethics undertaken by the author together with Professor Peter Kemp since the 1990s, on Basic ethical principles in European bioethics and biolaw. In this European approach to basic ethical principles in bioethics and biolaw......, the principles of autonomy, dignity, integrity and vulnerability are proposed as the most important ethical principles for respect for the human person in biomedical and biotechnological development. This approach to bioethics and biolaw is presented here in a short updated version that integrates the earlier...... research in a presentation of the present understanding of the basic ethical principles in bioethics and biolaw....

  11. Sorghum to Ethanol Research Initiative: Cooperative Research and Development Final Report, CRADA Number CRD-08-291

    Energy Technology Data Exchange (ETDEWEB)

    Wolfrum, E.

    2011-10-01

    The goal of this project was to investigate the feasibility of using sorghum to produce ethanol. The work performed included a detailed examination of the agronomics and composition of a large number of sorghum varieties, laboratory experiments to convert sorghum to ethanol, and economic and life-cycle analyses of the sorghum-to-ethanol process. This work showed that sorghum has a very wide range of composition, which depended on the specific sorghum cultivar as well as the growing conditions. The results of laboratory- and pilot-scale experiments indicated that a typical high-biomass sorghum variety performed very similarly to corn stover during the multi-step process required to convert biomass feedstocks to ethanol; yields of ethanol for sorghum were very similar to the corn stover used as a control in these experiments. Based on multi-year agronomic data and theoretical ethanol production, sorghum can achieve more than 1,300 gallons of ethanol per acre given the correct genetics and environment. In summary, sorghum may be a compelling dedicated bioenergy crop that could help provide a portion of the feedstocks required to produce renewable domestic transportation fuels.

  12. Contracts for field projects and supporting research on enhanced oil recovery. Progress review number 83, quarter ending June 30, 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-08-01

    Summaries of 41 research projects on enhanced recovery are presented under the following sections: (1) chemical flooding; (2) gas displacement; (3) thermal recovery; (4) geoscience technology; (5) resource assessment technology; and (6) reservoir classes. Each presentation gives the title of the project, contract number, research facility, contract date, expected completion data, amount of the award, principal investigator, and DOE program manager, and describes the objectives of the project and a summary of the technical progress.

  13. Breast Cancer and Estrogen-Alone Update

    Science.gov (United States)

    ... Current Issue Past Issues Research News From NIH Breast Cancer and Estrogen-Alone Update Past Issues / Summer 2006 ... hormone therapy does not increase the risk of breast cancer in postmenopausal women, according to an updated analysis ...

  14. The UK Burden of Injury Study – a protocol. [National Research Register number: M0044160889

    Directory of Open Access Journals (Sweden)

    Sleney Judith

    2007-11-01

    Full Text Available Abstract Background Globally and nationally large numbers of people are injured each year, yet there is little information on the impact of these injuries on people's lives, on society and on health and social care services. Measurement of the burden of injuries is needed at a global, national and regional level to be able to inform injured people of the likely duration of impairment; to guide policy makers in investing in preventative measures; to facilitate the evaluation and cost effectiveness of interventions and to contribute to international efforts to more accurately assess the global burden of injuries. Methods/Design A prospective, longitudinal multi-centre study of 1333 injured individuals, atttending Emergency Departments or admitted to hospital in four UK areas: Swansea, Surrey, Bristol and Nottingham. Specified quotas of patients with defined injuries covering the whole spectrum will be recruited. Participants (or a proxy will complete a baseline questionnaire regarding their injury and pre-injury quality of life. Follow up occurs at 1, 4, and 12 months post injury or until return to normal function within 12 months, with measures of health service utilisation, impairment, disability, and health related quality of life. National estimates of the burden of injuries will be calculated by extrapolation from the sample population to national and regional computerised hospital in-patient, emergency department and mortality data. Discussion This study will provide more detailed data on the national burden of injuries than has previously been available in any country and will contribute to international collaborative efforts to more accurately assess the global burden of injuries. The results will be used to advise policy makers on prioritisation of preventive measures, support the evaluation of interventions, and provide guidance on the likely impact and degree of impairment and disability following specific injuries.

  15. Getting the numbers right: statistical mischief and racial profiling in heart failure research.

    Science.gov (United States)

    Kahn, Jonathan

    2003-01-01

    The claim that blacks die from heart failure at a rate twice that of whites is informing efforts to develop and market the drug BiDil, which is currently undergoing clinical trials to be approved by the FDA as the first drug ever specified to treat African Americans--and only African Americans--for heart failure. The drug and its companion statistic have since come to play prominent roles in debates about so-called "racial profiling" in medicine and the legitimacy of using social categories of race in biomedical research. Nonetheless, this statistic is wrong. The most current data available place the black:white mortality ratio for heart failure at approximately 1.1:1. The article tells the story of attempts to get to the source of the supposed 2:1 mortality ratio and explores some of the implications of the acceptance of these erroneous data, both for the allocation of resources to combat disease and for our broader understanding of the nature and meaning of race.

  16. Literacy Update. Volume 18, Number 4

    Science.gov (United States)

    Steinberg, Jon, Ed.

    2009-01-01

    This newsletter, published five times a year, features articles on issues of concern to adult, family, and youth literacy practitioners, as well as recommended resources, announcements, and teaching strategies. This issue includes: (1) Career Pathways for High School Dropouts: A National Survey (Jon Steinberg); (2) Work (Elyse Barbell); (3) Peer…

  17. Literacy Update. Volume 19, Number 2

    Science.gov (United States)

    Gallagher, Jan, Ed.

    2010-01-01

    This newsletter, published five times a year, features articles on issues of concern to adult, family, and youth literacy practitioners, as well as recommended resources, announcements, and teaching strategies. This issue includes: (1) LAC [Literacy Assistance Center] Hits the International Stage (Elyse Barbell); (2) RAENing [Regional Adult…

  18. CIHR Canadian HIV Trials Network Coinfection and Concurrent Diseases Core Research Group: 2016 Updated Canadian HIV/Hepatitis C Adult Guidelines for Management and Treatment

    Science.gov (United States)

    Hull, Mark; Wong, Alex; Tseng, Alice; Giguère, Pierre; Barrett, Lisa; Haider, Shariq; Conway, Brian; Klein, Marina; Cooper, Curtis

    2016-01-01

    Background. Hepatitis C virus (HCV) coinfection occurs in 20–30% of Canadians living with HIV and is responsible for a heavy burden of morbidity and mortality. Purpose. To update national standards for management of HCV-HIV coinfected adults in the Canadian context with evolving evidence for and accessibility of effective and tolerable DAA therapies. The document addresses patient workup and treatment preparation, antiviral recommendations overall and in specific populations, and drug-drug interactions. Methods. A standing working group with HIV-HCV expertise was convened by The Canadian Institute of Health Research HIV Trials Network to review recently published HCV antiviral data and update Canadian HIV-HCV Coinfection Guidelines. Results. The gap in sustained virologic response between HCV monoinfection and HIV-HCV coinfection has been eliminated with newer HCV antiviral regimens. All coinfected individuals should be assessed for interferon-free, Direct Acting Antiviral HCV therapy. Regimens vary in content, duration, and success based largely on genotype. Reimbursement restrictions forcing the use of pegylated interferon is not acceptable if optimal patient care is to be provided. Discussion. Recommendations may not supersede individual clinical judgement. Treatment advances published since December 2015 are not considered in this document. PMID:27471521

  19. Methodological update in Medicina Intensiva.

    Science.gov (United States)

    García Garmendia, J L

    2018-04-01

    Research in the critically ill is complex by the heterogeneity of patients, the difficulties to achieve representative sample sizes and the number of variables simultaneously involved. However, the quantity and quality of records is high as well as the relevance of the variables used, such as survival. The methodological tools have evolved to offering new perspectives and analysis models that allow extracting relevant information from the data that accompanies the critically ill patient. The need for training in methodology and interpretation of results is an important challenge for the intensivists who wish to be updated on the research developments and clinical advances in Intensive Medicine. Copyright © 2017 Elsevier España, S.L.U. y SEMNIM. All rights reserved.

  20. Memory Updating and Mental Arithmetic.

    Science.gov (United States)

    Han, Cheng-Ching; Yang, Tsung-Han; Lin, Chia-Yuan; Yen, Nai-Shing

    2016-01-01

    Is domain-general memory updating ability predictive of calculation skills or are such skills better predicted by the capacity for updating specifically numerical information? Here, we used multidigit mental multiplication (MMM) as a measure for calculating skill as this operation requires the accurate maintenance and updating of information in addition to skills needed for arithmetic more generally. In Experiment 1, we found that only individual differences with regard to a task updating numerical information following addition (MUcalc) could predict the performance of MMM, perhaps owing to common elements between the task and MMM. In Experiment 2, new updating tasks were designed to clarify this: a spatial updating task with no numbers, a numerical task with no calculation, and a word task. The results showed that both MUcalc and the spatial task were able to predict the performance of MMM but only with the more difficult problems, while other updating tasks did not predict performance. It is concluded that relevant processes involved in updating the contents of working memory support mental arithmetic in adults.

  1. Memory updating and mental arithmetic

    Directory of Open Access Journals (Sweden)

    Cheng-Ching eHan

    2016-02-01

    Full Text Available Is domain-general memory updating ability predictive of calculation skills or are such skills better predicted by the capacity for updating specifically numerical information? Here, we used multidigit mental multiplication (MMM as a measure for calculating skill as this operation requires the accurate maintenance and updating of information in addition to skills needed for arithmetic more generally. In Experiment 1, we found that only individual differences with regard to a task updating numerical information following addition (MUcalc could predict the performance of MMM, perhaps owing to common elements between the task and MMM. In Experiment 2, new updating tasks were designed to clarify this: a spatial updating task with no numbers, a numerical task with no calculation, and a word task. The results showed that both MUcalc and the spatial task were able to predict the performance of MMM but only with the more difficult problems, while other updating tasks did not predict performance. It is concluded that relevant processes involved in updating the contents of working memory support mental arithmetic in adults.

  2. An Update on the Status of RR Lyrae Research - Report of the RRL2015 Meeting (October, Hungary) (Abstract)

    Science.gov (United States)

    Kolenberg, K.

    2016-06-01

    (Abstract only) In October 2015 we organized the first international meeting focused on RR Lyrae research, with the goal to discuss recent developments and future RR Lyrae plans. The Scientific rationale is the following:

  3. Non-Stationary Single-Channel Queuing System Features Research in Context of Number of Served Queries

    Directory of Open Access Journals (Sweden)

    Porshnev Sergey

    2017-01-01

    Full Text Available This work devoted to researching of mathematical model of non-stationary queuing system (NQS. Arrival rate in studied NQS λ(t is similar to rate which observed in practice in a real access control system of objects of mass events. Dependence of number of serviced requests from time was calculated. It is proven that the ratio value of served requests at the beginning of event to all served requests described by a deterministic function, depending on the average service rate μ¯$\\bar \\mu $ and the maximum value of the arrival rate function λ(t.

  4. Number names and number understanding

    DEFF Research Database (Denmark)

    Ejersbo, Lisser Rye; Misfeldt, Morten

    2014-01-01

    through using mathematical names for the numbers such as one-ten-one for 11 and five-ten-six for 56. The project combines the renaming of numbers with supporting the teaching with the new number names. Our hypothesis is that Danish children have more difficulties learning and working with numbers, because...... the Danish number names are more complicated than in other languages. Keywords: A research project in grade 0 and 1th in a Danish school, Base-10 system, two-digit number names, semiotic, cognitive perspectives....

  5. Impact of mesh points number on the accuracy of deterministic calculations of control rods worth for Tehran research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Boustani, Ehsan [Nuclear Science and Technology Research Institute (NSTRI), Tehran (Iran, Islamic Republic of); Amirkabir University of Technology, Tehran (Iran, Islamic Republic of). Energy Engineering and Physics Dept.; Khakshournia, Samad [Amirkabir University of Technology, Tehran (Iran, Islamic Republic of). Energy Engineering and Physics Dept.

    2016-12-15

    In this paper two different computational approaches, a deterministic and a stochastic one, were used for calculation of the control rods worth of the Tehran research reactor. For the deterministic approach the MTRPC package composed of the WIMS code and diffusion code CITVAP was used, while for the stochastic one the Monte Carlo code MCNPX was applied. On comparing our results obtained by the Monte Carlo approach and those previously reported in the Safety Analysis Report (SAR) of Tehran research reactor produced by the deterministic approach large discrepancies were seen. To uncover the root cause of these discrepancies, some efforts were made and finally was discerned that the number of spatial mesh points in the deterministic approach was the critical cause of these discrepancies. Therefore, the mesh optimization was performed for different regions of the core such that the results of deterministic approach based on the optimized mesh points have a good agreement with those obtained by the Monte Carlo approach.

  6. "Not Just for the Money?" How Financial Incentives Affect the Number of Publications at Danish Research Institutions

    DEFF Research Database (Denmark)

    Andersen, Lotte Bøgh; Pallesen, Thomas

    2008-01-01

    . We investigate how the introduction of financial incentives to publish affects the number of publications at 162 Danish research institutions (17 government research institutions and subunits of 10 universities) when the perception of the incentives is taken into account. The results show......Do public employees work "for the money?" Do financial incentives determine their work effort? The literature gives conflicting answers, but Frey (1997) offers a possible explanation: If financial incentives are perceived as supportive, they can "crowd in" intrinsic motivation and increase the work...... effort. But if financial incentives are perceived as controlling, the intrinsic motivation is "crowded out," and the work effort decreases with increasing financial incentives to work. However, the empirical evidence concerning Frey's proposition is limited, and our article aims to fill part of this gap...

  7. Review of Current Literature and Research on Gas Supersaturation and Gas Bubble Trauma: Special Publication Number 1, 1986.

    Energy Technology Data Exchange (ETDEWEB)

    Colt, John; Bouck, Gerald R.; Fidler, Larry

    1986-12-01

    This report presents recently published information and on-going research on the various areas of gas supersaturation. Growing interest in the effects of chronic gas supersaturation on aquatic animals has been due primarily to heavy mortality of salmonid species under hatchery conditions. Extensive examination of affected animals has failed to consistently identify pathogenic organisms. Water quality sampling has shown that chronic levels of gas supersaturation are commonly present during a significant period of the year. Small marine fish larvae are significantly more sensitive to gas supersaturation than salmonids. Present water quality criteria for gas supersaturation are not adequate for the protection of either salmonids under chronic exposure or marine fish larvae, especially in aquaria or hatcheries. To increase communication between interested parties in the field of gas supersaturation research and control, addresses and telephone numbers of all people responding to the questionnaire are included. 102 refs.

  8. Impact of mesh points number on the accuracy of deterministic calculations of control rods worth for Tehran research reactor

    International Nuclear Information System (INIS)

    Boustani, Ehsan; Amirkabir University of Technology, Tehran; Khakshournia, Samad

    2016-01-01

    In this paper two different computational approaches, a deterministic and a stochastic one, were used for calculation of the control rods worth of the Tehran research reactor. For the deterministic approach the MTRPC package composed of the WIMS code and diffusion code CITVAP was used, while for the stochastic one the Monte Carlo code MCNPX was applied. On comparing our results obtained by the Monte Carlo approach and those previously reported in the Safety Analysis Report (SAR) of Tehran research reactor produced by the deterministic approach large discrepancies were seen. To uncover the root cause of these discrepancies, some efforts were made and finally was discerned that the number of spatial mesh points in the deterministic approach was the critical cause of these discrepancies. Therefore, the mesh optimization was performed for different regions of the core such that the results of deterministic approach based on the optimized mesh points have a good agreement with those obtained by the Monte Carlo approach.

  9. Updated standardized endpoint definitions for transcatheter aortic valve implantation: The Valve Academic Research Consortium-2 consensus document

    NARCIS (Netherlands)

    A.P. Kappetein (Arie Pieter); S.J. Head (Stuart); P. Généreux (Philippe); N. Piazza (Nicolo); N.M. van Mieghem (Nicolas); E.H. Blackstone (Eugene); T.G. Brott (Thomas); D.J. Cohen (David J.); D.E. Cutlip (Donald); G.A. van Es (Gerrit Anne); R.T. Hahn (Rebecca); A.J. Kirtane (Ajay); M. Krucoff (Mitchell); S. Kodali (Susheel); M.J. Mack (Michael); R. Mehran (Roxana); J. Rodés-Cabau (Josep); P. Vranckx (Pascal); J.G. Webb (John); S.W. Windecker (Stephan); P.W.J.C. Serruys (Patrick); M.B. Leon (Martin)

    2012-01-01

    textabstractObjectives: The aim of the current Valvular Academic Research Consortium (VARC)-2 initiative was to revisit the selection and definitions of transcatheter aortic valve implantation (TAVI)- clinical endpoints to make them more suitable to the present and future needs of clinical trials.

  10. The Joint Space Operations Center Mission System and the Advanced Research, Collaboration, and Application Development Environment Status Update 2016

    Science.gov (United States)

    Murray-Krezan, Jeremy; Howard, Samantha; Sabol, Chris; Kim, Richard; Echeverry, Juan

    2016-05-01

    The Joint Space Operations Center (JSpOC) Mission System (JMS) is a service-oriented architecture (SOA) infrastructure with increased process automation and improved tools to enhance Space Situational Awareness (SSA) performed at the US-led JSpOC. The Advanced Research, Collaboration, and Application Development Environment (ARCADE) is a test-bed maintained and operated by the Air Force to (1) serve as a centralized test-bed for all research and development activities related to JMS applications, including algorithm development, data source exposure, service orchestration, and software services, and provide developers reciprocal access to relevant tools and data to accelerate technology development, (2) allow the JMS program to communicate user capability priorities and requirements to developers, (3) provide the JMS program with access to state-of-the-art research, development, and computing capabilities, and (4) support JMS Program Office-led market research efforts by identifying outstanding performers that are available to shepherd into the formal transition process. In this paper we will share with the international remote sensing community some of the recent JMS and ARCADE developments that may contribute to greater SSA at the JSpOC in the future, and share technical areas still in great need.

  11. Number needed to benefit from information (NNBI): proposal from a mixed methods research study with practicing family physicians.

    Science.gov (United States)

    Pluye, Pierre; Grad, Roland M; Johnson-Lafleur, Janique; Granikov, Vera; Shulha, Michael; Marlow, Bernard; Ricarte, Ivan Luiz Marques

    2013-01-01

    We wanted to describe family physicians' use of information from an electronic knowledge resource for answering clinical questions, and their perception of subsequent patient health outcomes; and to estimate the number needed to benefit from information (NNBI), defined as the number of patients for whom clinical information was retrieved for 1 to benefit. We undertook a mixed methods research study, combining quantitative longitudinal and qualitative research studies. Participants were 41 family physicians from primary care clinics across Canada. Physicians were given access to 1 electronic knowledge resource on handheld computer in 2008-2009. For the outcome assessment, participants rated their searches using a validated method. Rated searches were examined during interviews guided by log reports that included ratings. Cases were defined as clearly described searches where clinical information was used for a specific patient. For each case, interviewees described information-related patient health outcomes. For the mixed methods data analysis, quantitative and qualitative data were merged into clinical vignettes (each vignette describing a case). We then estimated the NNBI. In 715 of 1,193 searches for information conducted during an average of 86 days, the search objective was directly linked to a patient. Of those searches, 188 were considered to be cases. In 53 cases, participants associated the use of information with at least 1 patient health benefit. This finding suggested an NNBI of 14 (715/53). The NNBI may be used in further experimental research to compare electronic knowledge resources. A low NNBI can encourage clinicians to search for information more frequently. If all searches had benefits, the NNBI would be 1. In addition to patient benefits, learning and knowledge reinforcement outcomes are frequently reported.

  12. Muscles, Ligaments and Tendons Journal - Basic principles and recommendations in clinical and field Science Research: 2016 Update.

    Science.gov (United States)

    Padulo, Johnny; Oliva, Francesco; Frizziero, Antonio; Maffulli, Nicola

    2016-01-01

    The proper design and implementation of a study as well as a balanced and well-supported evaluation and interpretation of its main findings are of crucial importance when reporting and disseminating research. Also accountability, funding acknowledgement and adequately declaring any conflict of interest play a major role in science. Since the Muscles, Ligaments and Tendons Journal (MLTJ) is committed to the highest scientific and ethical standards, we encourage all Authors to take into account and to comply, as much as possible, to the contents and issues discussed in this official editorial. This could be useful for improving the quality of the manuscripts, as well as to stimulate interest and debate and to promote constructive change, reflecting upon uses and misuses within our disciplines belonging to the field of "Clinical and Sport - Science Research".

  13. Update: Health Status of Iranian Victims of Chemical Weapons / Ongoing Research Projects Addressing CW Health Effects in Iran

    International Nuclear Information System (INIS)

    Khateri, S.

    2007-01-01

    Use of chemical weapons against Iran during the 1980s was a horrifying epic in the annals of modern warfare, inflicting enormous suffering during the conflict that continues to the present day in the form of latent illness among survivors. Surviving victims suffer from a diverse range of chronic illnesses placing an enormous strain on the nation's medical infrastructure. To define the scope of this problem, the National Organization for Veteran's Affairs (Janbazan) established a subsidiary research department called Janbazan Medical and Engineering Research Center (JMERC). Beginning in 2000 JMERC has conducted epidemiological, clinical and basic scientific studies to characterize disease among chemical attack survivors and develop new therapeutic strategies. The primary JMERC mission has been to identify where resources may be allocated so as to most effectively treat patients with the greatest need - requiring a comprehensive picture of the major medical problems among this population. Accordingly, JMERC's initial task was to define the nature and distribution of serious chronic illness among CW survivors. Therefore epidemiological studies in CW-exposed Iranian populations are currently underway. Ultimately these studies will allow management of illness among CW-exposed populations that is both compassionate and cost-effective. A summary of the above mentioned research projects will be reported in this article. (author)

  14. Astrophysics Update 2

    CERN Document Server

    Mason, John W

    2006-01-01

    "Astrophysics Updates" is intended to serve the information needs of professional astronomers and postgraduate students about areas of astronomy, astrophysics and cosmology that are rich and active research spheres. Observational methods and the latest results of astronomical research are presented as well as their theoretical foundations and interrelations. The contributed commissioned articles are written by leading exponents in a format that will appeal to professional astronomers and astrophysicists who are interested in topics outside their own specific areas of research. This collection of timely reviews may also attract the interest of advanced amateur astronomers seeking scientifically rigorous coverage.

  15. Effectiveness of nutritional interventions on the functioning of children with ADHD and/or ASD. An updated review of research evidence.

    Science.gov (United States)

    Martí, Luis F

    2010-01-01

    Attention deficit - hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood and comprises a range of behavioral problems, including inattention, impulsivity and hyperactivity. ADHD has been investigated extensively during the last 30 years. At this point most researchers agree that ADHD is a problem of complex etiology that needs to be investigated as a function of complex interactions. Autism Spectrum Disorders (ASD) is a chronic disorder, with onset before three years of age. It is one of the fastest growing developmental disabilities in the United States and Puerto Rico. It presents with a wide range of stereotyped, repetitive behaviors, social and language impairment. Function and outcome is affected not only by core deficits but by associated behaviors such as hyperactivity, aggression, anxiety, and depression. Many studies have indicated that behavioral therapy and medication may be at least partially helpful in the treatment of children with ADHD or with ASD. Research on the effect of diet and nutrition on ADHD and autism has been increasing in the past two decades, particularly on the symptoms of hyperactivity and attention. Particular attention has focused on the role of food additives, refined sugar, food allergies, and fatty acid metabolism. It is imperative that data supporting new treatments should be scrutinized for scientific study design, clinical safety, and scientific validity, before embarking on them as modes of therapy. This updated review presents the evidence regarding the usefulness and limitations of the most frequent nutritional and dietary interventions in the treatment of ADHD and/or ASD.

  16. Closed-Cycle Hydrogen-Oxygen Regenerative Fuel Cell at the NASA Glenn Research Center-An Update

    Science.gov (United States)

    Bents, David J.; Chang, Bei-Jiann; Johnson, Donald W.; Garcia, Christopher P.

    2008-01-01

    The closed cycle hydrogen-oxygen proton exchange membrane (PEM) regenerative fuel cell (RFC) at the NASA Glenn Research Center has demonstrated multiple back-to-back contiguous cycles at rated power and round-trip efficiencies up to 52 percent. It is the first fully closed cycle RFC ever demonstrated. (The entire system is sealed; nothing enters or escapes the system other than electrical power and heat.) During fiscal year fiscal year (FY) FY06 to FY07, the system s numerous modifications and internal improvements focused on reducing parasitic power, heat loss, and noise signature; increasing its functionality as an unattended automated energy storage device; and in-service reliability.

  17. Muscles, Ligaments and Tendons Journal – Basic principles and recommendations in clinical and field Science Research: 2016 Update

    Science.gov (United States)

    Padulo, Johnny; Oliva, Francesco; Frizziero, Antonio; Maffulli, Nicola

    2016-01-01

    Summary The proper design and implementation of a study as well as a balanced and well-supported evaluation and interpretation of its main findings are of crucial importance when reporting and disseminating research. Also accountability, funding acknowledgement and adequately declaring any conflict of interest play a major role in science. Since the Muscles, Ligaments and Tendons Journal (MLTJ) is committed to the highest scientific and ethical standards, we encourage all Authors to take into account and to comply, as much as possible, to the contents and issues discussed in this official editorial. This could be useful for improving the quality of the manuscripts, as well as to stimulate interest and debate and to promote constructive change, reflecting upon uses and misuses within our disciplines belonging to the field of “Clinical and Sport - Science Research”. PMID:27331026

  18. A New Revision of the Solar Irradiance Climate Data Record Incorporates Recent Research into Proxies of Sunspot Darkening and the Sunspot Number Record

    Science.gov (United States)

    Coddington, O.; Lean, J.; Pilewskie, P.; Baranyi, T.; Snow, M. A.; Kopp, G.; Richard, E. C.; Lindholm, C.

    2017-12-01

    An operational climate data record (CDR) of total and spectral solar irradiance became available in November 2015 as part of the National Oceanographic and Atmospheric Administration's National Centers for Environmental Information Climate Data Record Program. The data record, which is updated quarterly, is available from 1610 to the present as yearly-average values and from 1882 to the present as monthly- and daily-averages, with associated time and wavelength-dependent uncertainties. It was developed jointly by the University of Colorado at Boulder's Laboratory for Atmospheric and Space Physics and the Naval Research Laboratory, and, together with the source code and supporting documentation, is available at https://www.ncdc.noaa.gov/cdr/. In the Solar Irradiance CDR, total solar irradiance (TSI) and solar spectral irradiance (SSI) are estimated from models that determine the changes from quiet Sun conditions arising from bright faculae and dark sunspots on the solar disk. The models are constructed using linear regression of proxies of solar sunspot and facular features with the approximately decade-long irradiance observations from the SOlar Radiation and Climate Experiment. A new revision of this data record was recently released in an ongoing effort to reduce solar irradiance uncertainties in two ways. First, the sunspot darkening proxy was revised using a new cross calibration of the current sunspot region observations made by the Solar Observing Optical Network with the historical records of the Royal Greenwich Observatory. This implementation affects modeled irradiances from 1882 - 1978. Second, the impact of a revised record of sunspot number by the Sunspot Index and Long-term Solar Observations center on modeled irradiances was assessed. This implementation provides two different reconstructions of historical, yearly-averaged irradiances from 1610-1881. Additionally, we show new, preliminary results that demonstrate improvements in modeled TSI by using

  19. Review: A neglected Flavivirus: an update on Zika virus in 2016 and the future direction of research.

    Science.gov (United States)

    Bharucha, Tehmina; Breuer, Judith

    2016-06-01

    The 2015-16 global emergence of Zika virus infection (ZIKV) and its link with Guillain-Barré Syndrome and microcephaly, at the tail-end of the Ebola epidemic, has provoked unease throughout the international community. The World Health Organisation declared ZIKV a public health emergency on 1st February 2016, but until the 31st March 2016 maintained that there was insufficient evidence that ZIKV was independently responsible for any serious complications. Our current understanding of this arthropod-borne flavivirus is still at an early stage. The first reported human infections were 60 years ago, and until the first outbreak in Micronesia in 2007, there were only 14 documented cases. Nonetheless, there are parallels that we can draw from our understanding of other related arbo-flaviviruses, such as dengue, Japanese encephalitis and West Nile viruses. This article provides a focussed review of the literature on ZIKV to date, with perspectives on the direction of future research. © 2016 British Neuropathological Society.

  20. [Update of the work of the ethics research in evaluating genetic research and its role as an external ethics committee biobank].

    Science.gov (United States)

    Alfonso Farnós, Iciar; Hernández Gil, Arantza; Rodríguez Velasco, María

    2013-01-01

    Research on human genome and its applications open great perspectives to improve human beings' health. However, these advances must never endanger the respect of dignity, freedom and rights of the participants in medical research, assuring prohibition of any way of discrimination because of genetic features. The Independent Research Boards (IRB), responsible for safeguarding rights, safety and well-being of the subjects taking part in the biomedical research, assess independently submitted genetic studies, clinical trials whose primary objective is obtaining genetic information and genetic sub-studies of clinical trials with drugs. Biobanks, as safeguarding means to preserve biological samples in suitable quality conditions, must be assigned to two external committees, a scientific one and an ethics one. External ethics committees of biobanks have to make the ethical assessment of the submissions of samples transfers and associated data, in order to carry out research projects. On the other hand, they have to advise biobanks on the compliance of ethical and legal principles, which, in many committees, has turned into the performance of informed consent forms which are in accordance with current laws.

  1. Public Interest Energy Research (PIER) Program. Final Project Report. California Energy Balance Update and Decomposition Analysis for the Industry and Building Sectors

    Energy Technology Data Exchange (ETDEWEB)

    de la Rue du Can, Stephane [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Hasanbeigi, Ali [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Sathaye, Jayant [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2010-12-01

    This report on the California Energy Balance version 2 (CALEB v2) database documents the latest update and improvements to CALEB version 1 (CALEB v1) and provides a complete picture of how energy is supplied and consumed in the State of California. The CALEB research team at Lawrence Berkeley National Laboratory (LBNL) performed the research and analysis described in this report. CALEB manages highly disaggregated data on energy supply, transformation, and end-use consumption for about 40 different energy commodities, from 1990 to 2008. This report describes in detail California's energy use from supply through end-use consumption as well as the data sources used. The report also analyzes trends in energy demand for the "Manufacturing" and "Building" sectors. Decomposition analysis of energy consumption combined with measures of the activity driving that consumption quantifies the effects of factors that shape energy consumption trends. The study finds that a decrease in energy intensity has had a very significant impact on reducing energy demand over the past 20 years. The largest impact can be observed in the industry sector where energy demand would have had increased by 358 trillion British thermal units (TBtu) if subsectoral energy intensities had remained at 1997 levels. Instead, energy demand actually decreased by 70 TBtu. In the "Building" sector, combined results from the "Service" and "Residential" subsectors suggest that energy demand would have increased by 264 TBtu (121 TBtu in the "Services" sector and 143 TBtu in the "Residential" sector) during the same period, 1997 to 2008. However, energy demand increased at a lesser rate, by only 162 TBtu (92 TBtu in the "Services" sector and 70 TBtu in the "Residential" sector). These energy intensity reductions can be indicative of energyefficiency improvements during the past 10 years. The research presented in this report provides a basis for developing an energy-efficiency performance index to measure

  2. Number names and number understanding

    DEFF Research Database (Denmark)

    Ejersbo, Lisser Rye; Misfeldt, Morten

    2014-01-01

    This paper concerns the results from the first year of a three-year research project involving the relationship between Danish number names and their corresponding digits in the canonical base 10 system. The project aims to develop a system to help the students’ understanding of the base 10 system...... the Danish number names are more complicated than in other languages. Keywords: A research project in grade 0 and 1th in a Danish school, Base-10 system, two-digit number names, semiotic, cognitive perspectives....

  3. Updated global soil map for the Weather Research and Forecasting model and soil moisture initialization for the Noah land surface model

    Science.gov (United States)

    DY, C. Y.; Fung, J. C. H.

    2016-08-01

    A meteorological model requires accurate initial conditions and boundary conditions to obtain realistic numerical weather predictions. The land surface controls the surface heat and moisture exchanges, which can be determined by the physical properties of the soil and soil state variables, subsequently exerting an effect on the boundary layer meteorology. The initial and boundary conditions of soil moisture are currently obtained via National Centers for Environmental Prediction FNL (Final) Operational Global Analysis data, which are collected operationally in 1° by 1° resolutions every 6 h. Another input to the model is the soil map generated by the Food and Agriculture Organization of the United Nations - United Nations Educational, Scientific and Cultural Organization (FAO-UNESCO) soil database, which combines several soil surveys from around the world. Both soil moisture from the FNL analysis data and the default soil map lack accuracy and feature coarse resolutions, particularly for certain areas of China. In this study, we update the global soil map with data from Beijing Normal University in 1 km by 1 km grids and propose an alternative method of soil moisture initialization. Simulations of the Weather Research and Forecasting model show that spinning-up the soil moisture improves near-surface temperature and relative humidity prediction using different types of soil moisture initialization. Explanations of that improvement and improvement of the planetary boundary layer height in performing process analysis are provided.

  4. An update on research priorities in hydrocephalus: overview of the third National Institutes of Health-sponsored symposium "Opportunities for Hydrocephalus Research: Pathways to Better Outcomes".

    Science.gov (United States)

    McAllister, James P; Williams, Michael A; Walker, Marion L; Kestle, John R W; Relkin, Norman R; Anderson, Amy M; Gross, Paul H; Browd, Samuel R

    2015-12-01

    Building on previous National Institutes of Health-sponsored symposia on hydrocephalus research, "Opportunities for Hydrocephalus Research: Pathways to Better Outcomes" was held in Seattle, Washington, July 9-11, 2012. Plenary sessions were organized into four major themes, each with two subtopics: Causes of Hydrocephalus (Genetics and Pathophysiological Modifications); Diagnosis of Hydrocephalus (Biomarkers and Neuroimaging); Treatment of Hydrocephalus (Bioengineering Advances and Surgical Treatments); and Outcome in Hydrocephalus (Neuropsychological and Neurological). International experts gave plenary talks, and extensive group discussions were held for each of the major themes. The conference emphasized patient-centered care and translational research, with the main objective to arrive at a consensus on priorities in hydrocephalus that have the potential to impact patient care in the next 5 years. The current state of hydrocephalus research and treatment was presented, and the following priorities for research were recommended for each theme. 1) Causes of Hydrocephalus-CSF absorption, production, and related drug therapies; pathogenesis of human hydrocephalus; improved animal and in vitro models of hydrocephalus; developmental and macromolecular transport mechanisms; biomechanical changes in hydrocephalus; and age-dependent mechanisms in the development of hydrocephalus. 2) Diagnosis of Hydrocephalus-implementation of a standardized set of protocols and a shared repository of technical information; prospective studies of multimodal techniques including MRI and CSF biomarkers to test potential pharmacological treatments; and quantitative and cost-effective CSF assessment techniques. 3) Treatment of Hydrocephalus-improved bioengineering efforts to reduce proximal catheter and overall shunt failure; external or implantable diagnostics and support for the biological infrastructure research that informs these efforts; and evidence-based surgical standardization with

  5. An increasing number of qualitative research papers in oncology and palliative care: does it mean a thorough development of the methodology of research?

    Directory of Open Access Journals (Sweden)

    Brunelli Cinzia

    2004-01-01

    Full Text Available Abstract Background In the second half of the nineties, a scientific debate about the usefulness of qualitative research in medicine began in the main medical journals as well as the amount of "qualitative" papers published on peer reviewed journals has noticeably increased during these last years. Nevertheless the label of qualitative methodology has been assigned to an heterogeneous collection of studies. Some of them show a complete awareness of the specificity of this kind of research, while others are still largely influenced by the quantitative paradigm prevailing in the medical field. The concern with the rigour and credibility of qualitative methods has lead to the development of a number of checklist for assessing qualitative research. The purposes of this review were to describe the quality of the development of qualitative research in the medical field, focusing on oncology and palliative care, and to discuss the applicability of a descriptive checklist. Methods A review was conducted on Medline and PsycINFO databases. On the basis of their abstract, papers found have been classified considering: publication year, kind of journal, paper type, data gathering method, sample size and declared methodological approach. A sub sample of the previous papers was than selected and their methodological characteristics were evaluated based on a descriptive checklist. Results 351 abstracts and 26 full papers were analysed. An increase over time in the number of qualitative studies is evident. While most of the papers before 1999 were published on nursing journals (43%, afterwards also medical journals were largely represented. Psychological journals increased from 7% to 12%. The 22% of studies used a sample size lower than 15 and the 15% did not specify the sample size in the abstract. The methodological approach was also often not specified and the percentage increased in the second time period (from 73% to 80%. Grounded theory was the most

  6. Models and applications for measuring the impact of health research: update of a systematic review for the Health Technology Assessment programme.

    Science.gov (United States)

    Raftery, James; Hanney, Steve; Greenhalgh, Trish; Glover, Matthew; Blatch-Jones, Amanda

    2016-10-01

    This report reviews approaches and tools for measuring the impact of research programmes, building on, and extending, a 2007 review. (1) To identify the range of theoretical models and empirical approaches for measuring the impact of health research programmes; (2) to develop a taxonomy of models and approaches; (3) to summarise the evidence on the application and use of these models; and (4) to evaluate the different options for the Health Technology Assessment (HTA) programme. We searched databases including Ovid MEDLINE, EMBASE, Cumulative Index to Nursing and Allied Health Literature and The Cochrane Library from January 2005 to August 2014. This narrative systematic literature review comprised an update, extension and analysis/discussion. We systematically searched eight databases, supplemented by personal knowledge, in August 2014 through to March 2015. The literature on impact assessment has much expanded. The Payback Framework, with adaptations, remains the most widely used approach. It draws on different philosophical traditions, enhancing an underlying logic model with an interpretative case study element and attention to context. Besides the logic model, other ideal type approaches included constructionist, realist, critical and performative. Most models in practice drew pragmatically on elements of several ideal types. Monetisation of impact, an increasingly popular approach, shows a high return from research but relies heavily on assumptions about the extent to which health gains depend on research. Despite usually requiring systematic reviews before funding trials, the HTA programme does not routinely examine the impact of those trials on subsequent systematic reviews. The York/Patient-Centered Outcomes Research Institute and the Grading of Recommendations Assessment, Development and Evaluation toolkits provide ways of assessing such impact, but need to be evaluated. The literature, as reviewed here, provides very few instances of a randomised trial

  7. Twenty-fifth water reactor safety information meeting: Proceedings. Volume 1: Plenary sessions; Pressure vessel research; BWR strainer blockage and other generic safety issues; Environmentally assisted degradation of LWR components; Update on severe accident code improvements and applications

    International Nuclear Information System (INIS)

    Monteleone, S.

    1998-03-01

    This three-volume report contains papers presented at the conference. The papers are printed in the order of their presentation in each session and describe progress and results of programs in nuclear safety research conducted in this country and abroad. Foreign participation in the meeting included papers presented by researchers from France, Japan, Norway, and Russia. The titles of the papers and the names of the authors have been updated and may differ from those that appeared in the final program of the meeting. This volume contains the following information: (1) plenary sessions; (2) pressure vessel research; (3) BWR strainer blockage and other generic safety issues; (4) environmentally assisted degradation of LWR components; and (5) update on severe accident code improvements and applications. Selected papers have been indexed separately for inclusion in the Energy Science and Technology Database

  8. Email-Based Informed Consent: Innovative Method for Reaching Large Numbers of Subjects for Data Mining Research

    Science.gov (United States)

    Lee, Lesley R.; Mason, Sara S.; Babiak-Vazquez, Adriana; Ray, Stacie L.; Van Baalen, Mary

    2015-01-01

    Since the 2010 NASA authorization to make the Life Sciences Data Archive (LSDA) and Lifetime Surveillance of Astronaut Health (LSAH) data archives more accessible by the research and operational communities, demand for data has greatly increased. Correspondingly, both the number and scope of requests have increased, from 142 requests fulfilled in 2011 to 224 in 2014, and with some datasets comprising up to 1 million data points. To meet the demand, the LSAH and LSDA Repositories project was launched, which allows active and retired astronauts to authorize full, partial, or no access to their data for research without individual, study-specific informed consent. A one-on-one personal informed consent briefing is required to fully communicate the implications of the several tiers of consent. Due to the need for personal contact to conduct Repositories consent meetings, the rate of consenting has not kept up with demand for individualized, possibly attributable data. As a result, other methods had to be implemented to allow the release of large datasets, such as release of only de-identified data. However the compilation of large, de-identified data sets places a significant resource burden on LSAH and LSDA and may result in diminished scientific usefulness of the dataset. As a result, LSAH and LSDA worked with the JSC Institutional Review Board Chair, Astronaut Office physicians, and NASA Office of General Counsel personnel to develop a "Remote Consenting" process for retrospective data mining studies. This is particularly useful since the majority of the astronaut cohort is retired from the agency and living outside the Houston area. Originally planned as a method to send informed consent briefing slides and consent forms only by mail, Remote Consenting has evolved into a means to accept crewmember decisions on individual studies via their method of choice: email or paper copy by mail. To date, 100 emails have been sent to request participation in eight HRP

  9. A pessimistic view of optimistic belief updating.

    Science.gov (United States)

    Shah, Punit; Harris, Adam J L; Bird, Geoffrey; Catmur, Caroline; Hahn, Ulrike

    2016-11-01

    Received academic wisdom holds that human judgment is characterized by unrealistic optimism, the tendency to underestimate the likelihood of negative events and overestimate the likelihood of positive events. With recent questions being raised over the degree to which the majority of this research genuinely demonstrates optimism, attention to possible mechanisms generating such a bias becomes ever more important. New studies have now claimed that unrealistic optimism emerges as a result of biased belief updating with distinctive neural correlates in the brain. On a behavioral level, these studies suggest that, for negative events, desirable information is incorporated into personal risk estimates to a greater degree than undesirable information (resulting in a more optimistic outlook). However, using task analyses, simulations, and experiments we demonstrate that this pattern of results is a statistical artifact. In contrast with previous work, we examined participants' use of new information with reference to the normative, Bayesian standard. Simulations reveal the fundamental difficulties that would need to be overcome by any robust test of optimistic updating. No such test presently exists, so that the best one can presently do is perform analyses with a number of techniques, all of which have important weaknesses. Applying these analyses to five experiments shows no evidence of optimistic updating. These results clarify the difficulties involved in studying human 'bias' and cast additional doubt over the status of optimism as a fundamental characteristic of healthy cognition. Copyright © 2016 The Author(s). Published by Elsevier Inc. All rights reserved.

  10. Leveraging Random Number Generation for Mastery of Learning in Teaching Quantitative Research Courses via an E-Learning Method

    Science.gov (United States)

    Boonsathorn, Wasita; Charoen, Danuvasin; Dryver, Arthur L.

    2014-01-01

    E-Learning brings access to a powerful but often overlooked teaching tool: random number generation. Using random number generation, a practically infinite number of quantitative problem-solution sets can be created. In addition, within the e-learning context, in the spirit of the mastery of learning, it is possible to assign online quantitative…

  11. Transit research update : March 2009.

    Science.gov (United States)

    SPECIAL............................................................................................................................3 : HUD and DOT Announce Interagency Partnership to Promote Sustainable Communities.......................................

  12. Design Research on Mathematics Education: Investigating the Progress of Indonesian Fifth Grade Students' Learning on Multiplication of Fractions with Natural Numbers

    Science.gov (United States)

    Shanty, Nenden Octavarulia; Hartono, Yusuf; Putri, Ratu Ilma Indra; de Haan, Dede

    2011-01-01

    This study aimed at investigating the progress of students' learning on multiplication fractions with natural numbers through the five activity levels based on Realistic Mathematics Education (RME) approach proposed by Streefland. Design research was chosen to achieve this research goal. In design research, the Hypothetical Learning Trajectory…

  13. Compendium of Experimental Cetane Numbers

    Energy Technology Data Exchange (ETDEWEB)

    Yanowitz, Janet [Ecoengineering, Sharonville, OH (United States); Ratcliff, Matthew A. [National Renewable Energy Lab. (NREL), Golden, CO (United States); McCormick, Robert L. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Taylor, J. D. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Murphy, M. J. [Battelle, Columbus, OH (United States)

    2017-02-22

    This report is an updated version of the 2014 Compendium of Experimental Cetane Number Data and presents a compilation of measured cetane numbers for pure chemical compounds. It includes all available single-compound cetane number data found in the scientific literature up until December 2016 as well as a number of previously unpublished values, most measured over the past decade at the National Renewable Energy Laboratory. This version of the compendium contains cetane values for 496 pure compounds, including 204 hydrocarbons and 292 oxygenates. 176 individual measurements are new to this version of the compendium, all of them collected using ASTM Method D6890, which utilizes an Ignition Quality Tester (IQT) a type of constant-volume combustion chamber. For many compounds, numerous measurements are included, often collected by different researchers using different methods. The text of this document is unchanged from the 2014 version, except for the numbers of compounds in Section 3.1, the Appendices, Table 1. Primary Cetane Number Data Sources and Table 2. Number of Measurements Included in Compendium. Cetane number is a relative ranking of a fuel's autoignition characteristics for use in compression ignition engines. It is based on the amount of time between fuel injection and ignition, also known as ignition delay. The cetane number is typically measured either in a single-cylinder engine or a constant-volume combustion chamber. Values in the previous compendium derived from octane numbers have been removed and replaced with a brief analysis of the correlation between cetane numbers and octane numbers. The discussion on the accuracy and precision of the most commonly used methods for measuring cetane number has been expanded, and the data have been annotated extensively to provide additional information that will help the reader judge the relative reliability of individual results.

  14. Communication Sciences Laboratory Quarterly Progress Report, Volume 9, Number 3: Research Programs of Some of the Newer Members of CSL.

    Science.gov (United States)

    Feinstein, Stephen H.; And Others

    The research reported in these papers covers a variety of communication problems. The first paper covers research on sound navigation by the blind and involves echo perception research and relevant aspects of underwater sound localization. The second paper describes a research program in acoustic phonetics and concerns such related issues as…

  15. WIMS Library updating

    International Nuclear Information System (INIS)

    Ravnik, M.; Trkov, A.; Holubar, A.

    1992-01-01

    At the end of 1990 the WIMS Library Update Project (WLUP) has been initiated at the International Atomic Energy Agency. The project was organized as an international research project, coordinated at the J. Stefan Institute. Up to now, 22 laboratories from 19 countries joined the project. Phase 1 of the project, which included WIMS input optimization for five experimental benchmark lattices, has been completed. The work presented in this paper describes also the results of Phase 2 of the Project, in which the cross sections based on ENDF/B-IV evaluated nuclear data library have been processed. (author) [sl

  16. Updated science systems on USCGC Healy

    Science.gov (United States)

    Chayes, D. N.; Roberts, S. D.; Arko, R. A.; Hiller, S. M.

    2008-12-01

    The USCG cutter Healy is the U.S. Arctic research icebreaker. Prior to the 2008 season, a number of upgrades and improvements were made to the science systems. These included the addition of two Bell BGM-3 marine gravity meters. The vessel's existing meterological sensors were enhanced with two RM Young model 85004 heated ultrasonic anemometers; a Paroscientific, Inc. model "MET-3A" air temperature, humidity and barometric pressure subsystem; and an RM Young model 50202 heated rain gauge. The flow through sea water system was updated with new flow meters, a SeaBird SBE45 thermosalinograph, long and a short wave radiation sensors, a Seapoint fluorometer. A Milltech Marine Smart Radio model SR161 Automatic Identification System (AIS) receiver and an updated interface to real-time winch and wire performance have been added. Our onboard real-time GIS has been updated to include real-time plotting of other ship tracks from our AIS receiver and the ability for users to save and share planned tracks. For the HLY0806 leg, we implemented a SWAP ship-to ship wireless connection for our two-ship operations with the Canadian icebreaker Louis S. St. Laurent similar to the one we implemented for our two-ship program with the Swedish icebreaker Oden in 2005. We updated our routine delivery of underway data to investigators, as well as a copy for archiving to the NSF-supported Marine Geoscience Data System (MGDS), using portable "boomerang" drives. An end-user workstation was added to accommodate increasing demand for onboard processing. Technical support for science on the Healy is supported by the U.S. National Science Foundation.

  17. Fulbright update

    Science.gov (United States)

    Opportunities to teach or perform postdoctoral research in the earth and atmospheric sciences under the Senior Scholar Fulbright awards program for 1984-1985 (Eos, March 1, 1983, p. 81) are available in 14 countries, according to the Council for International Exchange of Scholars.The countries and the specialization opportunities are Algeria, any specialization; Australia, mineral processing research; India, any specialization in geology or geophysics; Israel, environmental studies; Korea, any specialization; Lebanon, geophysics, geotectonics, and structural geology; Morocco, research methods in science education; Pakistan, geology, marine biology, and mineralogy; Poland, mining technology; Sudan, geology and remote sensing; Thailand, planning and environmental change; USSR, any specialization; Yugoslavia, any research specialization; and Zimbabwe, exploration geophysics and solid earth geophysics.

  18. Design Research on Mathematics Education: Investigating The Progress of Indonesian Fifth Grade Students’ Learning on Multiplication of Fractions With Natural Numbers

    Directory of Open Access Journals (Sweden)

    Nenden Octavarulia Shanty

    2011-07-01

    Full Text Available This study aimed at investigating the progress of students’ learning on multiplication fractions with natural numbers through the five activity levels based on Realistic Mathematics Education (RME approach proposed by Streefland. Design research was chosen to achieve this research goal. In design research, the Hypothetical Learning Trajectory (HLT plays important role as a design and research instrument. This HLT tested to thirty-seven students of grade five primary school (i.e.SDN 179 Palembang. The result of the classroom practices showed that measurement (length activity could stimulate students’ to produce fractions as the first level in learning multiplication of fractions with natural numbers. Furthermore, strategies and tools used by the students in partitioning gradually be developed into a more formal mathematics in which number line be used as the model of measuring situation and the model for more formal reasoning. The number line then could bring the students to the last activity level, namely on the way to rules for multiplying fractions with natural numbers. Based on this findings, it is suggested that Streefland’s five activity levels can be used as a guideline in learning multiplication of fractions with natural numbers in which the learning process become a more progressive learning.Keywords: multiplication fractions with natural numbers, measurement (length activity, design research, Hypothetical Learning Trajectory, model of, model for. DOI: http://dx.doi.org/10.22342/jme.2.2.749.147-162

  19. Late presentation for HIV care across Europe: update from the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) study, 2010 to 2013

    NARCIS (Netherlands)

    Mocroft, Amanda; Lundgren, Jens; Antinori, Andrea; Monforte, Antonella d'Arminio; Brännström, Johanna; Bonnet, Fabrice; Brockmeyer, Norbert; Casabona, Jordi; Castagna, Antonella; Costagliola, Dominique; de Wit, Stéphane; Fätkenheuer, Gerd; Furrer, Hansjakob; Jadand, Corinne; Johnson, Anne; Lazanas, Mario; Leport, Catherine; Moreno, Santiago; Mussini, Christina; Obel, Niels; Post, Frank; Reiss, Peter; Sabin, Caroline; Skaletz-Rorowski, Adriane; Suarez-Loano, Ignacio; Torti, Carlo; Warszawski, Josiane; Wittkop, Linda; Zangerle, Robert; Chene, Genevieve; Raben, Dorthe; Kirk, Ole; Touloumi, Giota; Meyer, Laurence; Dabis, François; Krause, Murielle Mary; Ghosn, Jade; Wit, Ferdinand; Prins, Maria; Bucher, Heiner; Gibb, Diana; del Amo, Julia; Thorne, Claire; Stephan, Christoph; Pérez-Hoyos, Santiago; Hamouda, Osamah; Bartmeyer, Barbara; Chkhartishvili, Nikoloz; Noguera-Julian, Antoni; D'Arminio Monforte, Antonella; Prieto, Luis; Conejo, Pablo Rojo; Soriano-Arandes, Antoni; Battegay, Manuel; Kouyos, Roger; Mussini, Cristina; Tookey, Pat; Miró, Jose M.; Konopnick, Deborah; Goetghebuer, Tessa; Sönnerborg, Anders; Teira, Ramon; Garrido, Myriam; Haerry, David; Chêne, Geneviève; Judd, Ali; Barger, Diana; Schwimmer, Christine; Termote, Monique; Campbell, Maria; Frederiksen, Casper M.; Friis-Moller, Nina; Kjaer, Jesper; Brandt, Rikke Salbøl; Berenguer, Juan; Bohlius, Julia; Bouteloup, Vincent; Cozzi-Lepri, Alessandro; Davies, Mary-Anne; Dorrucci, Maria; Dunn, David; Egger, Matthias; Guiguet, Marguerite; Grabar, Sophie; Lambotte, Olivier; Leroy, Valériane; Lodi, Sara; Matheron, Sophie; Monge, Susana; Nakagawa, Fumiyo; Paredes, Roger; Phillips, Andrew; Puoti, Massimo; Schomaker, Michael; Smit, Colette; Sterne, Jonathan; Thiebaut, Rodolphe; van der Valk, Marc; Wyss, Natasha

    2015-01-01

    Late presentation (LP) for HIV care across Europe remains a significant issue. We provide a cross-European update from 34 countries on the prevalence and risk factors of LP for 2010-2013. People aged >= 16 presenting for HIV care (earliest of HIV-diagnosis, first clinic visit or cohort enrolment)

  20. Class Evolution Tree: A Graphical Tool to Support Decisions on the Number of Classes in Exploratory Categorical Latent Variable Modeling for Rehabilitation Research

    Science.gov (United States)

    Kriston, Levente; Melchior, Hanne; Hergert, Anika; Bergelt, Corinna; Watzke, Birgit; Schulz, Holger; von Wolff, Alessa

    2011-01-01

    The aim of our study was to develop a graphical tool that can be used in addition to standard statistical criteria to support decisions on the number of classes in explorative categorical latent variable modeling for rehabilitation research. Data from two rehabilitation research projects were used. In the first study, a latent profile analysis was…

  1. Energy research information system (eris) projects report. volume 4, number 1. Report for December 1978-June 1979

    International Nuclear Information System (INIS)

    Boyd, C.A.; Jelinek, J.

    1979-06-01

    The goal of the Energy Research Information System (ERIS) is to provide an inventory of the energy related programs and research activities from 1974 to the present in the States of Montana, Nebraska, North Dakota, South Dakota and Wyoming. Areas of research covered include: coal, petroleum, oil shales, fission fuels, synthetic fuels, hydro-energy, renewable energy, resources, energy policy, reclamation, socioeconomic impacts, environmental impacts and land use. Each project description lists title, investigator(s), research institution, sponsor, funding, time frame, location, a descriptive abstract of the research and the titles of reports and/or publications generated by the research. All projects are indexed by location, personal names, organizations and subject keywords

  2. DUBNA: Update

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    Full text: At the annual session of the Plenipotentiaries Committee of the Joint Institute for Nuclear Research (JINR), Dubna, near Moscow in March, Institute Director Vladimir G. Kadyshevsky reported on important recent achievements. The Nuklotron superconducting accelerator has now been completed and is in operation. (A report will feature in a forthcoming edition of the CERN Courier.) The FOBOS multiple event spectrometer mounted in the heavy ion beam of the U-400M cyclotron is designed to record the products of nuclear reactions in the high mass and charge region with high efficiency. New experiments are envisaged. At the IBR research reactor a cryogenic moderator has been put into operation. Physics goals include generation of an impulse flux of cold neutrons. The neutron Fourier high resolution diffractometer was commissioned for polycrystal studies. Meanwhile an imaginative scheme to establish an International University using JINR research facilities and highly qualified personnel is being implemented. New appointments include Alexei Sissakian and Tzvetan Vylov as Vice-Directors, Nikolai Russakovitch as Chief Scientific Secretary, Vladislav Sarentzev as Chief Engineer and Alexandre Lebedev as Administrative Director. Western physicists elected members of JINR Scientific council include Ugo Amaldi and Lucien Montanet from CERN, Claude Detraz (IN2P3, Paris), Friedrich Dydak (Munich), Guido Piragino (Italy), George Trilling (Berkeley), Herwig Schopper (Germany) and Norbert Kroo (Hungary). Earlier this year saw the 80th birthday of Venedikt Dzhelepov, Honorary Director of JINR's Laboratory of Nuclear Problems

  3. Small Schools: The Numbers Tell a Story. A Review of the Research and Current Experiences. The Small Schools Workshop.

    Science.gov (United States)

    Klonsky, Michael

    A compelling body of research shows that when students are part of smaller and more intimate learning communities, they are more successful. The latest research demonstrates that small schools, particularly schools of choice, have a measurably positive impact on inner-city students, especially those from minority and low-income families. The…

  4. Combining the power of stories and the power of numbers: mixed methods research and mixed studies reviews.

    Science.gov (United States)

    Pluye, Pierre; Hong, Quan Nha

    2014-01-01

    This article provides an overview of mixed methods research and mixed studies reviews. These two approaches are used to combine the strengths of quantitative and qualitative methods and to compensate for their respective limitations. This article is structured in three main parts. First, the epistemological background for mixed methods will be presented. Afterward, we present the main types of mixed methods research designs and techniques as well as guidance for planning, conducting, and appraising mixed methods research. In the last part, we describe the main types of mixed studies reviews and provide a tool kit and examples. Future research needs to offer guidance for assessing mixed methods research and reporting mixed studies reviews, among other challenges.

  5. Assessing the Workforce Development Needs of Healthcare Employers in Southeastern Wisconsin. Research Brief. Volume 98, Number 3

    Science.gov (United States)

    Million, Laura

    2010-01-01

    Despite near-record unemployment rates in the region, southeast Wisconsin's healthcare sector faces a distinctive challenge: finding sufficient numbers of qualified and trained workers to fill current and future job openings. A May 2009 University of Wisconsin-Milwaukee analysis found that one out of every four full-time job openings and one out…

  6. Updating systematic reviews: an international survey.

    Directory of Open Access Journals (Sweden)

    Chantelle Garritty

    a formal written policy for updating SRs. This research marks the first baseline data available on updating from an organizational perspective.

  7. Late presentation for HIV care across Europe: update from the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) study, 2010 to 2013

    OpenAIRE

    Hamouda, Osamah; Gunsenheimer-Bartmeyer, Barbara

    2015-01-01

    Late presentation (LP) for HIV care across Europe remains a significant issue. We provide a cross-European update from 34 countries on the prevalence and risk factors of LP for 2010–2013. People aged ≥ 16 presenting for HIV care (earliest of HIV-diagnosis, first clinic visit or cohort enrolment) after 1 January 2010 with available CD4 count within six months of presentation were included. LP was defined as presentation with a CD4 count 

  8. Update in urethral stents.

    Science.gov (United States)

    Bahouth, Z; Meyer, G; Yildiz, G; Nativ, O; Moskovitz, B

    2016-10-01

    Urethral stents were first introduced in 1988, and since then, they have undergone significant improvements. However, they did not gain a wide popularity and their use is limited to a small number of centers around the world. Urethral stents can be used in the entire urethra and for various and diverse indications. In the anterior urethra, it can be used to treat urethral strictures. In the prostatic urethra, they can be used for the treatment of prostatic obstruction, including benign, malignant and iatrogenic prostatic obstruction. Moreover, although not widely used, it can be also applied for the treatment of posterior urethral stricture and bladder neck contracture, usually resulting in urinary incontinence and the need for subsequent procedures. Our main experience are with Allium urethral stents, and as such, we provide the latest updates in urethral stents with special emphasis on the various types of Allium urethral stents: bulbar, prostatic and bladder neck stents.

  9. Research of the method of pseudo-random number generation based on asynchronous cellular automata with several active cells

    Directory of Open Access Journals (Sweden)

    Bilan Stepan

    2017-01-01

    Full Text Available To date, there are many tasks that are aimed at studying the dynamic changes in physical processes. These tasks do not give advance known result. The solution of such problems is based on the construction of a dynamic model of the object. Successful structural and functional implementation of the object model can give a positive result in time. This approach uses the task of constructing artificial biological objects. To solve such problems, pseudo-random number generators are used, which also find wide application for information protection tasks. Such generators should have good statistical properties and give a long repetition period of the generated pseudo-random bit sequence. This work is aimed at improving these characteristics. The paper considers the method of forming pseudo-random sequences of numbers on the basis of aperiodic cellular automata with two active cells. A pseudo-random number generator is proposed that generates three bit sequences. The first two bit sequences are formed by the corresponding two active cells in the cellular automaton. The third bit sequence is the result of executing the XOR function over the bits of the first two sequences and it has better characteristics compared to them. The use of cellular automata with two active cells allowed to improve the statistical properties of the formed bit sequence, as well as its repetition period. This is proved by using graphical tests for generators built based on cellular automata using the neighborhoods of von Neumann and Moore. The tests showed high efficiency of the generator based on an asynchronous cellular automaton with the neighborhood of Moore. The proposed pseudo-random number generators have good statistical properties, which makes it possible to use them in information security systems, as well as for simulation tasks of various dynamic processes.

  10. Hispanic update.

    Science.gov (United States)

    Haub, C

    1987-11-01

    The Hispanic population of the US grew from 14.6 million at the time of the 1980 Census to 18.8 million by March 1987 -- a 30% growth -- according to the Current Population Survey (CPS). This rate of growth was 5 times that of the non-Hispanic population. These new estimates incorporate an allowance for estimated illegal immigration since 1980, which adds 141,000 persons to the Hispanic population each year. Yet, this increase is offset by an annual emigration estimate of 31,000, which now is being used. The net effect is to add 110,000 more Hispanics each year, a figure which accounts for 18% of US population growth since 1980. The CPS showed that about 1/4 of Hispanic families were below the 1986 poverty level and that overall their median income was about 1/3 less than the income of non-Hispanic families -- $19,995 in contrast to $30,231. There was no income increase for the Hispanic population since 1981. Both Cubans and Puerto Ricans have shown a decrease since 1985 in the CPS estimates. The Census Bureau will be conducting research to determine the possible causes of the decrease.

  11. Impact of GDP, spending on R&D, number of universities and scientific journals on research publications in pharmacological sciences in Middle East.

    Science.gov (United States)

    Meo, S A; Usmani, A M; Vohra, M S; Bukhari, I A

    2013-10-01

    Research in pharmacological science is vital to support the health needs of human beings. Measuring the research output provides information that forms the basis of strategic decisions. This study aimed to investigate the impact of Gross Domestic Product (GDP), spending on Research and Development (R&D), number of universities and scientific journals on research documents (papers), citable documents, citations per document and H-index in pharmacological science among Middle East countries. All the 16 Middle East countries were included in the study. The information regarding GDP, spending on R&D, total number of universities and indexed scientific journals were collected. We recorded the total number of research documents, citable documents, citations per document and H-index in pharmacological science during the period 1996-2011. The main sources for information were World Bank, Web of Science, Journal Citation Reports (Thomson Reuters) and SCI-mago/Scopus. The mean per capita GDP of all the Middle East countries is 18125.49±5386.28 US$, spending on R&D 0.63±0.28% of GDP in US$, number of universities 36.56±11.33 and mean ISI indexed journal are 8.25±3.93. The number of research documents published in pharmacological science among the Middle East countries during the period 1996-2011 is 1344.44±499.34; citable documents 1286.37±476.34; citations per document 7.62± 0.84; and H-index is 30.68±6.32. There was a positive correlation between spending on R&D and citations per documents (r = 0.56, p = 0.02), H-Index (r = 0.56, p = 0.02); number of universities and research documents (r = 0.72, p = 0.002), citable documents (r = 0.72, p = 0.001); ISI indexed journals and research documents (r = 0.88, p = 0.0001), citable documents (r = 0.88, p = 0.0001), H-Index (r = 0.67, p = 0.004). However, there was no correlation between the GDP per capita and research outcome in pharmacological science. There is a positive association between spending on R&D, number of

  12. Update on the Methodological Quality of Research Published in The American Journal of Sports Medicine: Comparing 2011-2013 to 10 and 20 Years Prior.

    Science.gov (United States)

    Brophy, Robert H; Kluck, Dylan; Marx, Robert G

    2016-05-01

    In recent years, the number of articles in The American Journal of Sports Medicine (AJSM) has risen dramatically, with an increasing emphasis on evidence-based medicine in orthopaedics and sports medicine. Despite the increase in the number of articles published in AJSM over the past decade, the methodological quality of articles in 2011-2013 has improved relative to those in 2001-2003 and 1991-1993. Meta-analysis. All articles published in AJSM during 2011-2013 were reviewed and classified by study design. For each article, the use of pertinent methodologies, such as prospective data collection, randomization, control groups, and blinding, was recorded. The frequency of each article type and the use of evidence-based techniques were compared relative to 1991-1993 and 2001-2003 by use of Pearson χ(2) testing. The number of research articles published in AJSM more than doubled from 402 in 1991-1993 and 423 in 2001-2003 to 953 in 2011-2013. Case reports decreased from 15.2% to 10.6% to 2.1% of articles published over the study period (P < .001). Cadaveric/human studies and meta-analysis/literature review studies increased from 5.7% to 7.1% to 12.4% (P < .001) and from 0.2% to 0.9% to 2.3% (P = .01), respectively. Randomized, prospective clinical trials increased from 2.7% to 5.9% to 7.4% (P = .007). Fewer studies used retrospective compared with prospective data collection (P < .001). More studies tested an explicit hypothesis (P < .001) and used controls (P < .001), randomization (P < .001), and blinding of those assessing outcomes (P < .001). Multi-investigator trials increased (P < .001), as did the proportion of articles citing a funding source (P < .001). Despite a dramatic increase in the number of published articles, the research published in AJSM shifted toward more prospective, randomized, controlled, and blinded designs during 2011-2013 compared with 2001-2003 and 1991-1993, demonstrating a continued improvement in methodological quality. © 2015 The

  13. Hispanic Teen Pregnancy and Birth Rates: Looking Behind the Numbers. Child Trends Research Brief. Publication #2005-01

    Science.gov (United States)

    Ryan, Suzanne; Franzetta, Kerry; Manlove, Jennifer

    2005-01-01

    This research brief focuses on the birth, pregnancy, contraceptive, and relationship behaviors of Hispanic teens because they represent an important risk group. Teen pregnancy and birth rates for U.S. teens have declined dramatically in recent years. Yet for Hispanic teens, reductions in teen pregnancy and childbearing have lagged behind that of…

  14. 77 FR 28588 - Proposed Priorities-American Overseas Research Centers Program; CFDA Number 84.274A

    Science.gov (United States)

    2012-05-15

    .... scholars conducting overseas research that is vital to understanding the history, culture, economy... offering foreign language courses to enhance career training or preparation for transfer to four-year... obligations of recipients thereof; or (4) Raise novel legal or policy issues arising out of legal mandates...

  15. Vocal Production of Young Children with Disabilities during Child-Robot Interactions. Social Robots Research Reports, Number 5

    Science.gov (United States)

    Dunst, Carl J.; Hamby, Deborah W.; Trivette, Carol M.; Prior, Jeremy; Derryberry, Graham

    2013-01-01

    The effects of a socially interactive robot on the vocalization production of five children with disabilities (4 with autism, 1 with a sensory processing disorder) were the focus of the intervention study described in this research report. The interventions with each child were conducted over 4 or 5 days in the children's homes and involved…

  16. Invitation to number theory

    CERN Document Server

    Ore, Oystein

    2017-01-01

    Number theory is the branch of mathematics concerned with the counting numbers, 1, 2, 3, … and their multiples and factors. Of particular importance are odd and even numbers, squares and cubes, and prime numbers. But in spite of their simplicity, you will meet a multitude of topics in this book: magic squares, cryptarithms, finding the day of the week for a given date, constructing regular polygons, pythagorean triples, and many more. In this revised edition, John Watkins and Robin Wilson have updated the text to bring it in line with contemporary developments. They have added new material on Fermat's Last Theorem, the role of computers in number theory, and the use of number theory in cryptography, and have made numerous minor changes in the presentation and layout of the text and the exercises.

  17. Research on beam characteristics in a large-Fresnel-number unstable-waveguide hybrid resonator with parabolic mirrors.

    Science.gov (United States)

    Wang, Wei; Qin, Yingxiong; Xiao, Yu; Zhong, Lijing; Wu, Chao; Wang, Zhen; Wan, Wen; Tang, Xiahui

    2016-07-20

    Large-Fresnel-number unstable-waveguide hybrid resonators employing spherical resonator mirrors suffer from spherical aberration, which adversely affects beam quality and alignment sensitivity. In this paper, we present experimental and numerical wave-optics simulations of the beam characteristics of a negative-branch hybrid resonator having parabolic mirrors with a large equivalent Fresnel number in the unstable direction. These results are compared with a resonator using spherical mirrors. Using parabolic mirrors, the output beam has a smaller beam spot size and higher power density at the focal plane. We found that the power extraction efficiency is 3.5% higher when compared with a resonator using spherical mirrors as the cavity length was varied between -1 and 1 mm from the ideal confocal resonator. In addition, the power extraction efficiency is 5.6% higher for mirror tilt angles varied between -6 and 6 mrad. Furthermore, the output propagating field is similar to a converging wave for a spherical mirror resonator and the output beam direction deviates 3.5 mrad from the optical axis. The simulation results are in good agreement with the experimental results.

  18. Number Sense on the Number Line

    Science.gov (United States)

    Woods, Dawn Marie; Ketterlin Geller, Leanne; Basaraba, Deni

    2018-01-01

    A strong foundation in early number concepts is critical for students' future success in mathematics. Research suggests that visual representations, like a number line, support students' development of number sense by helping them create a mental representation of the order and magnitude of numbers. In addition, explicitly sequencing instruction…

  19. Contracts for field projects and supporting research on enhanced oil recovery. Progress review number 86, quarter ending March 31, 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-05-01

    Summaries are presented for 37 enhanced oil recovery contracts being supported by the Department of Energy. The projects are grouped into gas displacement methods, thermal recovery methods, geoscience technology, reservoir characterization, and field demonstrations in high-priority reservoir classes. Each summary includes the objectives of the project and a summary of the technical progress, as well as information on contract dates, size of award, principal investigator, and company or facility doing the research.

  20. Research on the superimposed frame number of terahertz digital holograms in double-exposed phase retrieval algorithm

    Science.gov (United States)

    Hu, Jia-qi; Li, Qi; Chen, Guang-hao

    2015-10-01

    Phase retrieval algorithm is gradually applied to the terahertz in-line digital holography, as its effectiveness in the removal of the zero-order diffraction light and twin image. Based on the experiments, the reconstruction results of the double-exposed phase retrieval algorithm are obtained which demonstrate that the method can improve the quality of reconstructed images, compared to the angular spectrum method. Furthermore, the influence of the superimposed frame number of the holograms in double-exposed phase retrieval algorithm is discussed. The result shows that the recording time can be reduced by reasonably decreasing the frames of the holograms and it contributes to real-time imaging and the algorithm practicality is also further improved.

  1. Updates in ophthalmic pathology.

    Science.gov (United States)

    Mendoza, Pia R; Grossniklaus, Hans E

    2017-05-01

    Ophthalmic pathology has a long history and rich heritage in the field of ophthalmology. This review article highlights updates in ophthalmic pathology that have developed significantly through the years because of the efforts of committed individuals and the confluence of technology such as molecular biology and digital pathology. This is an exciting period in the history of ocular pathology, with cutting-edge techniques paving the way for new developments in diagnostics, therapeutics, and research. Collaborations between ocular oncologists and pathologists allow for improved and comprehensive patient care. Ophthalmic pathology continues to be a relevant specialty that is important in the understanding and clinical management of ocular disease, education of eye care providers, and overall advancement of the field.

  2. Updates in ophthalmic pathology

    Directory of Open Access Journals (Sweden)

    Pia R Mendoza

    2017-01-01

    Full Text Available Ophthalmic pathology has a long history and rich heritage in the field of ophthalmology. This review article highlights updates in ophthalmic pathology that have developed significantly through the years because of the efforts of committed individuals and the confluence of technology such as molecular biology and digital pathology. This is an exciting period in the history of ocular pathology, with cutting-edge techniques paving the way for new developments in diagnostics, therapeutics, and research. Collaborations between ocular oncologists and pathologists allow for improved and comprehensive patient care. Ophthalmic pathology continues to be a relevant specialty that is important in the understanding and clinical management of ocular disease, education of eye care providers, and overall advancement of the field.

  3. Cohort Profile Update

    DEFF Research Database (Denmark)

    Omland, Lars Haukali; Ahlström, Magnus Glindvad; Obel, Niels

    2014-01-01

    of Causes of Death, the Danish National Prescription Registry, the Attainment Register and the Integrated Database for Labour Market Research to get information on vital status, migration, cancer, hospital contacts, causes of death, dispensed prescriptions, education and employment. Using this design, rates......The DHCS is a cohort of all HIV-infected individuals seen in one of the eight Danish HIV centres after 31 December 1994. Here we update the 2009 cohort profile emphasizing the development of the cohort. Every 12-24 months, DHCS is linked with the Danish Civil Registration System (CRS) in order...... to extract an age- and sex-matched comparison cohort from the general population, as well as cohorts of family members of the HIV-infected patients and of the comparison cohort. The combined cohort is linked with CRS, the Danish Cancer Registry, the Danish National Hospital Registry, the Danish Registry...

  4. Design Research on Mathematics Education: Investigating The Progress of Indonesian Fifth Grade Students’ Learning on Multiplication of Fractions With Natural Numbers

    Directory of Open Access Journals (Sweden)

    Nenden Octavarulia Shanty

    2011-07-01

    Full Text Available This study aimed at investigating the progress of students’ learning onmultiplication fractions with natural numbers through the five activitylevels based on Realistic Mathematics Education (RME approachproposed by Streefland. Design research was chosen to achieve thisresearch goal. In design research, the Hypothetical Learning Trajectory(HLT plays important role as a design and research instrument. ThisHLT tested to thirty-seven students of grade five primary school (i.e.SDN 179 Palembang.The result of the classroom practices showed that measurement (lengthactivity could stimulate students’ to produce fractions as the first levelin learning multiplication of fractions with natural numbers.Furthermore, strategies and tools used by the students in partitioninggradually be developed into a more formal mathematics in whichnumber line be used as the model of measuring situation and the modelfor more formal reasoning. The number line then could bring thestudents to the last activity level, namely on the way to rules formultiplying fractions with natural numbers. Based on this findings, it is suggested that Streefland’s five activity levels can be used as aguideline in learning multiplication of fractions with natural numbers in which the learning process become a more progressive learning.

  5. Reducing the number of laboratory animals used in tissue engineering research by restricting the variety of animal models. Articular cartilage tissue engineering as a case study

    NARCIS (Netherlands)

    Vries, R.B.M. de; Buma, P.; Leenaars, M.; Ritskes-Hoitinga, M.; Gordijn, B.

    2012-01-01

    The use of laboratory animals in tissue engineering research is an important underexposed ethical issue. Several ethical questions may be raised about this use of animals. This article focuses on the possibilities of reducing the number of animals used. Given that there is considerable debate about

  6. Biodiesel Performance with Modern Engines. Cooperative Research and Development Final Report, CRADA Number CRD-05-153

    Energy Technology Data Exchange (ETDEWEB)

    McCormick, Robert [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-01-29

    NREL and the National Biodiesel Board (NBB) will work cooperatively to assess the effects of biodiesel blends on the performance of modern diesel engines and emissions control systems meeting increasingly strict emissions standards. This work will include research to understand the impact of biodiesel blends on the operation and durability of particle filters and NOx control sorbents/catalysts, to quantify the effect on emission control systems performance, and to understand effects on engine component durability. Work to assess the impact of biodiesel blends on real world fleet operations will be performed. Also, research to develop appropriate ASTM standards for biodiesel quality and stability will be conducted. The cooperative project will involve engine testing and fleet evaluation studies at NREL using biodiesel from a variety of sources. In addition, NREL will work with NBB to set up an Industrial Steering Committee to design the scope for the various projects and to provide technical oversight to these projects. NREL and NBB will cooperatively communicate the study results to as broad an audience as possible.

  7. Design and development for updating national 1:50,000 topographic databases in China

    Directory of Open Access Journals (Sweden)

    CHEN Jun

    2010-02-01

    Full Text Available 1.1 Objective Map databases are irreplaceable national treasure of immense importance. Their currency referring to its consistency with respect to the real world plays a critical role in its value and applications. The continuous updating of map databases at 1:50,000 scales is a massive and difficult task for larger countries of the size of more than several million’s kilometer squares. This paper presents the research and technological development to support the national map updating at 1:50,000 scales in China, including the development of updating models and methods, production tools and systems for large-scale and rapid updating, as well as the design and implementation of the continuous updating workflow. 1.2 Methodology The updating of map databases is different than its original creation, and a number of new problems should be solved, such as change detection using latest multi-source data, incremental object revision and relation amendment. The methodology of this paper consists of the following three parts: 1 Examine the four key aspects of map database updating and develop basic updating models/methods, such as currentness-oriented integration of multi-resource data, completeness-based incremental change detection in the context of existing datasets, consistency-aware processing of updated data sets, and user-friendly propagation and services of updates. 2 Design and develop specific software tools and packages to support the large-scale updating production with high resolution imagery and large-scale data generalization, such as map generalization, GIS-supported change interpretation from imagery, DEM interpolation, image matching-based orthophoto generation, data control at different levels. 3 Design a national 1:50,000 databases updating strategy and its production workflow, including a full coverage updating pattern characterized by all element topographic data modeling, change detection in all related areas, and whole process

  8. Impact of GDP, spending on R&D, the number of universities and scientific journals on research publications in environmental sciences in the Middle East

    Directory of Open Access Journals (Sweden)

    Sultan Ayoub Meo

    2013-10-01

    Full Text Available Objectives: This study aimed to assess the impact of the Gross Domestic Product (GDP, spending on Research and Development (R&D, the number of universities and scientific journals on the published research documents, citable documents, citations per document and H-index in environmental sciences in the Middle East countries. Materials and Methods: All the 16 Middle East countries were included in the study. Information regarding the GDP, spending on R&D, the total number of universities and indexed journals was collected. Total number of research documents (papers, citable documents, citations per document and H-index in environmental sciences during the period 1996-2011 was recorded. The study used the World Bank, SCI-mago/Scopus, Web of Science, Journal Citation Reports (Thomson Reuters as the main sources of information. Results: The mean GDP per capita of all the Middle East countries amounted to 18 125.49±5386.28 US$, spending on R&D was 0.63±0.28 US$, the number of universities equaled 36.56±11.33 and mean ISI indexed journals amounted to 8.25±3.93. The mean number of research documents published in environmental sciences in the Middle East countries during the period 1996-2011 was 2202.12±883.98; citable documents: 2156.87±865.09; citations per document: 8.74±0.73; and the H-index: 35.37±6.17. There was a positive correlation between the money spent on R&D and citations per documents (r = 0.6, p = 0.01, H-Index (r = 0.6, p = 0.01; the number of universities and a total of research documents (r = 0.65, p = 0.006, citable documents (r = 0.65, p = 0.006, H-Index (r = 0.50, p = 0.04, as well as ISI indexed journals and total research documents (r = 0.94, p = 0.0001, citable documents (r = 0.94, p = 0.0001, H-Index (r = 0.73, p = 0.001. Conclusions: The Middle East countries which spend more on R&D and which have a large number of universities and ISI indexed journals are likely to produce more significant volume of research papers in

  9. Impact of GDP, spending on R&D, the number of universities and scientific journals on research publications in environmental sciences in the Middle East.

    Science.gov (United States)

    Meo, Sultan Ayoub; Al Masri, Abeer A; Usmani, Adnan Mahmood; Halepoto, Dost Muhammad

    2013-10-01

    This study aimed to assess the impact of the Gross Domestic Product (GDP), spending on Research and Development (R&D), the number of universities and scientific journals on the published research documents, citable documents, citations per document and H-index in environmental sciences in the Middle East countries. All the 16 Middle East countries were included in the study. Information regarding the GDP, spending on R&D, the total number of universities and indexed journals was collected. Total number of research documents (papers), citable documents, citations per document and H-index in environmental sciences during the period 1996-2011 was recorded. The study used the World Bank, SCI-mago/Scopus, Web of Science, Journal Citation Reports (Thomson Reuters) as the main sources of information. The mean GDP per capita of all the Middle East countries amounted to 18 125.49±5386.28 US$, spending on R&D was 0.63±0.28 US$, the number of universities equaled 36.56±11.33 and mean ISI indexed journals amounted to 8.25±3.93. The mean number of research documents published in environmental sciences in the Middle East countries during the period 1996-2011 was 2202.12±883.98; citable documents: 2156.87±865.09; citations per document: 8.74±0.73; and the H-index: 35.37±6.17. There was a positive correlation between the money spent on R&D and citations per documents (r = 0.6, p = 0.01), H-Index (r = 0.6, p = 0.01); the number of universities and a total of research documents (r = 0.65, p = 0.006), citable documents (r = 0.65, p = 0.006), H-Index (r = 0.50, p = 0.04), as well as ISI indexed journals and total research documents (r = 0.94, p = 0.0001), citable documents (r = 0.94, p = 0.0001), H-Index (r = 0.73, p = 0.001). The Middle East countries which spend more on R&D and which have a large number of universities and ISI indexed journals are likely to produce more significant volume of research papers in the field of environmental science.

  10. Breaking New Ground: An Exploratory Study of the Role and Education of the Advanced Neonatal Nurse Practitioner. Researching Professional Education. Research Reports Series Number 4.

    Science.gov (United States)

    Redshaw, M. E.; Harris, A.

    A British research study documented and defined the level of functioning of advanced neonatal nurse practitioners (ANNPs) in comparison with qualified nurses and junior pediatric medical staff working in the same neonatal units. Subjects were ANNPs, ANNP students, and clinician mentors in 10 units. Data were collected through interviews,…

  11. Scale Up of Malonic Acid Fermentation Process: Cooperative Research and Development Final Report, CRADA Number CRD-16-612

    Energy Technology Data Exchange (ETDEWEB)

    Schell, Daniel J [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2018-04-16

    The goal of this work is to use the large fermentation vessels in the National Renewable Energy Laboratory's (NREL) Integrated Biorefinery Research Facility (IBRF) to scale-up Lygos' biological-based process for producing malonic acid and to generate performance data. Initially, work at the 1 L scale validated successful transfer of Lygos' fermentation protocols to NREL using a glucose substrate. Outside of the scope of the CRADA with NREL, Lygos tested their process on lignocellulosic sugars produced by NREL at Lawrence Berkeley National Laboratory's (LBNL) Advanced Biofuels Process Development Unit (ABPDU). NREL produced these cellulosic sugar solutions from corn stover using a separate cellulose/hemicellulose process configuration. Finally, NREL performed fermentations using glucose in large fermentors (1,500- and 9,000-L vessels) to intermediate product and to demonstrate successful performance of Lygos' technology at larger scales.

  12. High Penetration Photovoltaic Power Electronics and Energy Management Technology Research, Development and Demonstration: Cooperative Research and Development Final Report, CRADA Number CRD-13-517

    Energy Technology Data Exchange (ETDEWEB)

    Hudgins, Andrew P. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2018-01-25

    Advanced Energy Industries, Inc., will partner with DOE's National Renewable Energy Laboratory (NREL) to conduct research and development to demonstrate technologies that will increase the penetration of photovoltaic (PV) technologies for commercial and utility applications. Standard PV power control systems use simple control techniques that only provide real power to the grid. A focus of this partnership is to demonstrate how state of the art control and power electronic technologies can be combined to create a utility interactive control platform.

  13. ADAS Update and Maintainability

    Science.gov (United States)

    Watson, Leela R.

    2010-01-01

    Since 2000, both the National Weather Service Melbourne (NWS MLB) and the Spaceflight Meteorology Group (SMG) have used a local data integration system (LOIS) as part of their forecast and warning operations. The original LOIS was developed by the Applied Meteorology Unit (AMU) in 1998 (Manobianco and Case 1998) and has undergone subsequent improvements. Each has benefited from three-dimensional (3-D) analyses that are delivered to forecasters every 15 minutes across the peninsula of Florida. The intent is to generate products that enhance short-range weather forecasts issued in support of NWS MLB and SMG operational requirements within East Central Florida. The current LDIS uses the Advanced Regional Prediction System (ARPS) Data Analysis System (AD AS) package as its core, which integrates a wide variety of national, regional, and local observational data sets. It assimilates all available real-time data within its domain and is run at a finer spatial and temporal resolution than current national or regional-scale analysis packages. As such, it provides local forecasters with a more comprehensive understanding of evolving fine-scale weather features. Over the years, the LDIS has become problematic to maintain since it depends on AMU-developed shell scripts that were written for an earlier version of the ADAS software. The goals of this task were to update the NWS MLB/SMG LDIS with the latest version of ADAS, incorporate new sources of observational data, and upgrade and modify the AMU-developed shell scripts written to govern the system. In addition, the previously developed ADAS graphical user interface (GUI) was updated. Operationally, these upgrades will result in more accurate depictions of the current local environment to help with short-range weather forecasting applications, while also offering an improved initialization for local versions of the Weather Research and Forecasting (WRF) model used by both groups.

  14. Oil sands development update

    International Nuclear Information System (INIS)

    1999-01-01

    A detailed review and update of oil sands development in Alberta are provided covering every aspect of the production and economic aspects of the industry. It is pointed out that at present oil sands account for 28 per cent of Canadian crude oil production, expected to reach 50 per cent by 2005. Based on recent announcements, a total of 26 billion dollars worth of projects are in progress or planned; 20 billion dollars worth of this development is in the Athabasca area, the remainder in Cold Lake and other areas. The current update envisages up to 1,800,000 barrels per day by 2008, creating 47,000 new jobs and total government revenues through direct and indirect taxes of 118 billion dollars. Provinces other than Alberta also benefit from these development, since 60 per cent of all employment and income created by oil sands production is in other parts of Canada. Up to 60 per cent of the expansion is for goods and services and of this, 50 to 55 per cent will be purchased from Canadian sources. The remaining 40 per cent of the new investment is for engineering and construction of which 95 per cent is Canadian content. Aboriginal workforce by common consent of existing operators matches regional representation (about 13 per cent), and new developers are expected to match these standards. Planned or ongoing development in environmental protection through improved technologies and optimization, energy efficiency and improved tailings management, and active support of flexibility mechanisms such as emission credits trading, joint implementation and carbon sinks are very high on the industry's agenda. The importance of offsets are discussed extensively along with key considerations for international negotiations, as well as further research of other options such as sequestration, environmentally benign disposal of waste, and enhanced voluntary action

  15. Cooperative Research and Development Agreement Final Report for Cooperative Research and Development Agreement Number ORNL93-0237 Adhesive Bonding Technologies for Automotive Structural Composites; TOPICAL

    International Nuclear Information System (INIS)

    Boeman, R.G.

    2001-01-01

    In 1993, the Oak Ridge National Laboratory (ORNL) entered into a Cooperative Research and Development Agreement (CRADA) with the Automotive Composites Consortium (ACC) to conduct research and development that would overcome technological hurdles to the adhesive bonding of current and future automotive materials. This effort is part of a larger Department of Energy (DOE) program to promote the use of lighter weight materials in automotive structures for the purpose of increasing fuel efficiency and reducing environmental pollutant emissions. In accomplishing this mission, the bonding of similar and dissimilar materials was identified as being of primary importance to the automotive industry since this enabling technology would give designers the freedom to choose from an expanded menu of low mass materials for component weight reduction. The research undertaken under this CRADA addresses the following areas of importance: bulk material characterization, structural fracture mechanics, modeling/characterization, process control and nondestructive evaluation (PC/NDE), manufacturing demonstration, and advanced processing. For the bulk material characterization task, the individual material properties of the adherends and adhesives were characterized. This included generating a database of mechanical and physical properties, after identifying and developing standard test methods to obtain properties. The structural fracture mechanics task concentrated on test development to characterize the fracture toughness of adhesively bonded joints subjected to Mode I, Mode II and mixed-mode conditions. Standard test procedures for quantifying an adhesive/adherend system's resistance to crack growth were developed for use by industry. In the modeling/characterization task, fracture mechanics-based design guidelines and predictive methodologies have been developed which will facilitate iteration on design concepts for bonded joints while alleviating the need for extensive testing

  16. Cannabis and Psychopathology : Update 2004

    OpenAIRE

    Grover, Sandeep; Basu, Debasish

    2004-01-01

    The study of cannabis use and psychopathology remains an interesting area from both academic and pragmatic perspectives. This article provides an update on the progress made in this area over the past decade or so. Psychopathology and psychiatric syndromes associated with cannabis use that have received research attention in recent years include cannabis withdrawal, cannabis and psychotic disorders (especially schizophrenia), depression, anxiety, and cognitive impairment. Status of a specific...

  17. Profile updating for information systems

    International Nuclear Information System (INIS)

    Abrantes, J.F.

    1983-02-01

    Profiles updating methods were analysed. A method suitable to the characteristics of the system used in the research (SDI/CIN/CNEN) that uses as the selection criterio the threshold and weights criterion, was determined. Relevance weighting theory was described and experiments to verify precision were carried out. The improvements obtained were good nevertheless more significant tests are required to attain more reliable results. (Author) [pt

  18. An Update on Memory Reconsolidation Updating.

    Science.gov (United States)

    Lee, Jonathan L C; Nader, Karim; Schiller, Daniela

    2017-07-01

    The reactivation of a stored memory in the brain can make the memory transiently labile. During the time it takes for the memory to restabilize (reconsolidate) the memory can either be reduced by an amnesic agent or enhanced by memory enhancers. The change in memory expression is related to changes in the brain correlates of long-term memory. Many have suggested that such retrieval-induced plasticity is ideally placed to enable memories to be updated with new information. This hypothesis has been tested experimentally, with a translational perspective, by attempts to update maladaptive memories to reduce their problematic impact. We review here progress on reconsolidation updating studies, highlighting their translational exploitation and addressing recent challenges to the reconsolidation field. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Research

    African Journals Online (AJOL)

    The study followed a qualitative research design using semi-structured interviews with full-time SA- or foreign-qualified specialists at. Kimberley Hospital ... average number of weekly hours spent on undergraduate student training ... The best place to learn is at the bedside; a student should see the patient, read up and ...

  20. Research

    African Journals Online (AJOL)

    abp

    2014-08-29

    Aug 29, 2014 ... Page number not for citation purposes ... Pan African Medical Journal – ISSN: 1937- 8688 (www.panafrican-med-journal.com). Published in partnership with the African Field Epidemiology Network (AFENET). (www.afenet.net). Research .... and education, hence a higher risk of morbidity and mortality and a.

  1. Research

    African Journals Online (AJOL)

    Workshop on {topic}; research project; clinical practical experience. Outputs. Tangible products/by-products of activities (but not whether students learned anything). Certificates of completion; records of actions by participants (i.e. log books); number of students at clinical site. Intermediate outcomes Learning connected to ...

  2. Research

    African Journals Online (AJOL)

    YouTube, TED and other podcast websites. Other researchers have also documented their procedures. Corl et al.[5] describe the basic process of producing a podcast, and Jham et al.[6] list a number of universities actively doing podcasts. Besides the lecture podcasts, we have also captured numerous clinical.

  3. Seasonal variation of atmospheric particle number concentrations, new particle formation and atmospheric oxidation capacity at the high Arctic site Villum Research Station, Station Nord

    DEFF Research Database (Denmark)

    Nguyen, Q. T.; Glasius, Marianne; Sørensen, Lise L.

    2016-01-01

    This work presents an analysis of the physical properties of sub-micrometer aerosol particles measured at the high Arctic site Villum Research Station, Station Nord (VRS), northeast Greenland, between July 2010 and February 2013. The study focuses on particle number concentrations, particle numbe...... mass origin. A map of event occurrence probability was computed, indicating that southerly air masses from over the Greenland Sea were more likely linked to those events. © Author(s) 2016....

  4. Academic career intentions in the life sciences: Can research self-efficacy beliefs explain low numbers of aspiring physician and female scientists?

    Science.gov (United States)

    Epstein, Nurith; Fischer, Martin R

    2017-01-01

    A lack of physician scientists as well as a high female dropout rate from academic medicine and basic life sciences is a concern in many countries. The current study analyzes academic career intentions within a sample of recent doctoral graduates from medicine and basic life sciences (N = 1109), focusing on research self-efficacy beliefs as explanatory variable of gender and disciplinary differences. To ensure that differences in research self-efficacy could not be attributed solely to objective scientific performance, we controlled for number of publications and dissertation grade. The results of multivariate analyses pointed to a strong and significant association between research self-efficacy and academic career intentions (ß = 0.49, pacademic career intentions of medical doctoral graduates were no longer significant when controlling for research self-efficacy. Within the field of medicine, female doctoral graduates expressed lower research self-efficacy beliefs and academic career intentions. When controlling for research self-efficacy, the correlation between gender and academic career intention was no longer significant. In contrast, no gender differences were found within the basic life sciences with respect to neither academic career intentions nor research self-efficacy.

  5. Special number issued in commemoration of 10th anniversary of NEDO's industrial technology research and development department; NEDO sangyo gijutsu kenkyu kaihatsu bumon 10 shunenshi

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-01

    This special number is issued in commemoration of 10th anniversary of NEDO's industrial technology research and development department, to look back its R and D activity results and help the future projects. This department was established in 1988, based on the Law of Establishment of the Industrial Technology Research and Development System, and started its activities as the central institute for positively promoting the R and D of the industrial technologies, centered by the basic and advanced areas, while in closely cooperation with oversea institutes. During this period, the department has been pursuing various projects, including large-scale industrial technology R and D projects transferred from the Agency of Industrial Science and Technology; R and D projects for technologies for the industrial bases of the next generation and medical/welfare equipment technologies; projects for assistance to international cooperative research teams; projects for establishing facilities as research bases necessary for promoting R and D of advanced industrial technologies; and, more recently, projects for establishing measures to cope with global environmental problems. NEDO has been playing a role of managing and controlling various large-size R and D projects, both in name and reality, taking over the projects which had been promoted by the Agency of Industrial Science and Technology. This special number outlines the R and D projects NEDO has pursued in the past 10 years. (NEDO)

  6. Nuclear technology review 2005 update

    International Nuclear Information System (INIS)

    2005-08-01

    The year 2004 marked the 50th anniversary of civilian nuclear power generation. While the current outlook for nuclear energy remains mixed, there is clearly a sense of rising expectations. Both the OECD International Energy Agency and the IAEA adjusted their medium-term projections for nuclear power upwards. The IAEA now projects 423 - 592 GW(e) of nuclear power installed worldwide in 2030, compared to 366 GW(e) at the end of 2004. This is driven by nuclear power's performance record, by growing energy needs around the world coupled with rising oil and natural gas prices, by new environmental constraints including entry-into-force of the Kyoto Protocol, by concerns about energy supply security in a number of countries, and by ambitious expansion plans in several key countries. National research on advanced reactor designs continues on all reactor categories - water cooled, gas cooled, liquid metal cooled, and hybrid systems. Five members of the US-initiated Generation IV International Forum (GIF) signed a framework agreement on international collaboration in research and development on Generation IV nuclear energy systems in February 2005. The IAEA's International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) grew to 23 members. It completed a series of case studies testing its assessment methodology and the final report on the updated INPRO methodology was published in December. The realization of the International Thermonuclear Experimental Reactor, ITER, came closer with the announcement on 28 June 2005 by the ITER parties. The aim of ITER is to demonstrate the scientific and technological feasibility of fusion energy by constructing a functional fusion power plant. Nuclear technology developments are rapid and cover many fields of application. Not all can be covered in this update review, but certain key areas and trends are covered where these are seen to be of significant interest to IAEA Member States, and which are of relevance to and have

  7. Analytic number theory

    CERN Document Server

    Matsumoto, Kohji

    2002-01-01

    The book includes several survey articles on prime numbers, divisor problems, and Diophantine equations, as well as research papers on various aspects of analytic number theory such as additive problems, Diophantine approximations and the theory of zeta and L-function Audience Researchers and graduate students interested in recent development of number theory

  8. Studying the potential impact of automated document classification on scheduling a systematic review update

    Science.gov (United States)

    2012-01-01

    Background Systematic Reviews (SRs) are an essential part of evidence-based medicine, providing support for clinical practice and policy on a wide range of medical topics. However, producing SRs is resource-intensive, and progress in the research they review leads to SRs becoming outdated, requiring updates. Although the question of how and when to update SRs has been studied, the best method for determining when to update is still unclear, necessitating further research. Methods In this work we study the potential impact of a machine learning-based automated system for providing alerts when new publications become available within an SR topic. Some of these new publications are especially important, as they report findings that are more likely to initiate a review update. To this end, we have designed a classification algorithm to identify articles that are likely to be included in an SR update, along with an annotation scheme designed to identify the most important publications in a topic area. Using an SR database containing over 70,000 articles, we annotated articles from 9 topics that had received an update during the study period. The algorithm was then evaluated in terms of the overall correct and incorrect alert rate for publications meeting the topic inclusion criteria, as well as in terms of its ability to identify important, update-motivating publications in a topic area. Results Our initial approach, based on our previous work in topic-specific SR publication classification, identifies over 70% of the most important new publications, while maintaining a low overall alert rate. Conclusions We performed an initial analysis of the opportunities and challenges in aiding the SR update planning process with an informatics-based machine learning approach. Alerts could be a useful tool in the planning, scheduling, and allocation of resources for SR updates, providing an improvement in timeliness and coverage for the large number of medical topics needing SRs

  9. Dali server update.

    Science.gov (United States)

    Holm, Liisa; Laakso, Laura M

    2016-07-08

    The Dali server (http://ekhidna2.biocenter.helsinki.fi/dali) is a network service for comparing protein structures in 3D. In favourable cases, comparing 3D structures may reveal biologically interesting similarities that are not detectable by comparing sequences. The Dali server has been running in various places for over 20 years and is used routinely by crystallographers on newly solved structures. The latest update of the server provides enhanced analytics for the study of sequence and structure conservation. The server performs three types of structure comparisons: (i) Protein Data Bank (PDB) search compares one query structure against those in the PDB and returns a list of similar structures; (ii) pairwise comparison compares one query structure against a list of structures specified by the user; and (iii) all against all structure comparison returns a structural similarity matrix, a dendrogram and a multidimensional scaling projection of a set of structures specified by the user. Structural superimpositions are visualized using the Java-free WebGL viewer PV. The structural alignment view is enhanced by sequence similarity searches against Uniprot. The combined structure-sequence alignment information is compressed to a stack of aligned sequence logos. In the stack, each structure is structurally aligned to the query protein and represented by a sequence logo. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  10. Sagan numbers

    OpenAIRE

    Mendonça, J. Ricardo G.

    2012-01-01

    We define a new class of numbers based on the first occurrence of certain patterns of zeros and ones in the expansion of irracional numbers in a given basis and call them Sagan numbers, since they were first mentioned, in a special case, by the North-american astronomer Carl E. Sagan in his science-fiction novel "Contact." Sagan numbers hold connections with a wealth of mathematical ideas. We describe some properties of the newly defined numbers and indicate directions for further amusement.

  11. Fibonacci numbers

    CERN Document Server

    Vorob'ev, Nikolai Nikolaevich

    2011-01-01

    Fibonacci numbers date back to an 800-year-old problem concerning the number of offspring born in a single year to a pair of rabbits. This book offers the solution and explores the occurrence of Fibonacci numbers in number theory, continued fractions, and geometry. A discussion of the ""golden section"" rectangle, in which the lengths of the sides can be expressed as a ration of two successive Fibonacci numbers, draws upon attempts by ancient and medieval thinkers to base aesthetic and philosophical principles on the beauty of these figures. Recreational readers as well as students and teacher

  12. Alternative energies. Updates on progress

    International Nuclear Information System (INIS)

    Ferreira, German

    2013-01-01

    Presents fundamental and applied research of alternative energies. Address key pillars in the alternative energy field, such as: biomass energy, hydrogen energy, solar energy, wind energy, hydroelectric power, geothermal energy and their environmental implications, with the most updated progress. Includes the life cycle assessment and thermoeconomic analysis as tools for evaluating and optimising environmental and cost subjects. This book presents nine chapters based on fundamental and applied research of alternative energies. At the present time, the challenge is that technology has to come up with solutions that can provide environmentally friendly energy supply options that are able to cover the current world energy demand. Experts around the world are working on these issues for providing new solutions that will break the existing technological barriers. This book aims to address key pillars in the alternative energy field, such as: biomass energy, hydrogen energy, solar energy, wind energy, hydroelectric power, geothermal energy and their environmental implications, with the most updated progress for each pillar. It also includes the life cycle assessment (LCA) and thermoeconomic analysis (TA) as tools for evaluating and optimising environmental and cost subjects. Chapters are organized into fundamental research, applied research and future trends; and written for engineers, academic researches and scientists.

  13. Alternative energies. Updates on progress

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, German (ed.) [CIRCE - Centre of Research for Energy Resources and Consumption, Zaragoza (Spain)

    2013-07-01

    Presents fundamental and applied research of alternative energies. Address key pillars in the alternative energy field, such as: biomass energy, hydrogen energy, solar energy, wind energy, hydroelectric power, geothermal energy and their environmental implications, with the most updated progress. Includes the life cycle assessment and thermoeconomic analysis as tools for evaluating and optimising environmental and cost subjects. This book presents nine chapters based on fundamental and applied research of alternative energies. At the present time, the challenge is that technology has to come up with solutions that can provide environmentally friendly energy supply options that are able to cover the current world energy demand. Experts around the world are working on these issues for providing new solutions that will break the existing technological barriers. This book aims to address key pillars in the alternative energy field, such as: biomass energy, hydrogen energy, solar energy, wind energy, hydroelectric power, geothermal energy and their environmental implications, with the most updated progress for each pillar. It also includes the life cycle assessment (LCA) and thermoeconomic analysis (TA) as tools for evaluating and optimising environmental and cost subjects. Chapters are organized into fundamental research, applied research and future trends; and written for engineers, academic researches and scientists.

  14. Late presentation for HIV care across Europe: update from the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) study, 2010 to 2013.

    Science.gov (United States)

    Mocroft, Amanda; Lundgren, Jens; Antinori, Andrea; Monforte, Antonella d'Arminio; Brännström, Johanna; Bonnet, Fabrice; Brockmeyer, Norbert; Casabona, Jordi; Castagna, Antonella; Costagliola, Dominique; De Wit, Stéphane; Fätkenheuer, Gerd; Furrer, Hansjakob; Jadand, Corinne; Johnson, Anne; Lazanas, Mario; Leport, Catherine; Moreno, Santiago; Mussini, Christina; Obel, Niels; Post, Frank; Reiss, Peter; Sabin, Caroline; Skaletz-Rorowski, Adriane; Suarez-Loano, Ignacio; Torti, Carlo; Warszawski, Josiane; Wittkop, Linda; Zangerle, Robert; Chene, Genevieve; Raben, Dorthe; Kirk, Ole

    2015-01-01

    Late presentation (LP) for HIV care across Europe remains a significant issue. We provide a cross-European update from 34 countries on the prevalence and risk factors of LP for 2010-2013. People aged ≥ 16 presenting for HIV care (earliest of HIV-diagnosis, first clinic visit or cohort enrollment) after 1 January 2010 with available CD4 count within six months of presentation were included. LP was defined as presentation with a CD4 count defining event (at any CD4), in the six months following HIV diagnosis. Logistic regression investigated changes in LP over time. A total of 30,454 people were included. The median CD4 count at presentation was 368/mm(3) (interquartile range (IQR) 193-555/mm(3)), with no change over time (p = 0.70). In 2010, 4,775/10,766 (47.5%) were LP whereas in 2013, 1,642/3,375 (48.7%) were LP (p = 0.63). LP was most common in central Europe (4,791/9,625, 49.8%), followed by northern (5,704/11,692; 48.8%), southern (3,550/7,760; 45.8%) and eastern Europe (541/1,377; 38.3%; p < 0.0001). There was a significant increase in LP in male and female people who inject drugs (PWID) (adjusted odds ratio (aOR)/year later 1.16; 95% confidence interval (CI): 1.02-1.32), and a significant decline in LP in northern Europe (aOR/year later 0.89; 95% CI: 0.85-0.94). Further improvements in effective HIV testing strategies, with a focus on vulnerable groups, are required across the European continent.

  15. Screening and Brief Interventions: Research Update. Prevention Update

    Science.gov (United States)

    Higher Education Center for Alcohol, Drug Abuse, and Violence Prevention, 2012

    2012-01-01

    Developed in 1993 at the University of Washington, Brief Alcohol Screening and Intervention for College Students (BASICS) is a preventive intervention program to reduce drinking and enhance awareness about alcohol-related issues. BASICS targets college students who are considered at risk because of heavy drinking behaviors. The brief intervention…

  16. Red Hill Updates

    Science.gov (United States)

    This and other periodic updates are intended to keep the public informed on major progress being made to protect public health and the environment at the Red Hill Underground Fuel Storage Facility in Hawaii.

  17. Invasive Species Science Update (No. 6)

    Science.gov (United States)

    Paula Fornwalt

    2013-01-01

    The sixth issue of the Rocky Mountain Research Station's (RMRS) Invasive Species Science Update is now complete. Published approximately once per year, this newsletter keeps managers and other users up-to-date with recently completed and ongoing research by RMRS scientists, and covers breaking news related to invasive species issues. The newsletter is produced by...

  18. Eulerian numbers

    CERN Document Server

    Petersen, T Kyle

    2015-01-01

    This text presents the Eulerian numbers in the context of modern enumerative, algebraic, and geometric combinatorics. The book first studies Eulerian numbers from a purely combinatorial point of view, then embarks on a tour of how these numbers arise in the study of hyperplane arrangements, polytopes, and simplicial complexes. Some topics include a thorough discussion of gamma-nonnegativity and real-rootedness for Eulerian polynomials, as well as the weak order and the shard intersection order of the symmetric group. The book also includes a parallel story of Catalan combinatorics, wherein the Eulerian numbers are replaced with Narayana numbers. Again there is a progression from combinatorics to geometry, including discussion of the associahedron and the lattice of noncrossing partitions. The final chapters discuss how both the Eulerian and Narayana numbers have analogues in any finite Coxeter group, with many of the same enumerative and geometric properties. There are four supplemental chapters throughout, ...

  19. Email Reminders Increase the Frequency That Pet Owners Update Their Microchip Information

    Directory of Open Access Journals (Sweden)

    Katie Goodwin

    2018-01-01

    Full Text Available Stray animals with incorrect microchip details are less likely to be reclaimed, and unclaimed strays are at increased risk of euthanasia. A retrospective cohort study was performed using 394,747 cats and 904,909 dogs registered with Australia’s largest microchip database to describe animal characteristics, determine whether annual email reminders increased the frequency that owners updated their information, and to compare frequencies of microchip information updates according to pet and owner characteristics. More than twice as many dogs (70% than cats (30% were registered on the database; the most numerous pure-breeds were Ragdoll cats and Staffordshire Bull Terrier dogs, and the number of registered animals per capita varied by Australian state or territory. Owners were more likely (p < 0.001 to update their details soon after they were sent a reminder email, compared to immediately before that email, and there were significant (p < 0.001 differences in the frequency of owner updates by state or territory of residence, animal species, animal age, and socioeconomic index of the owner’s postcode. This research demonstrates that email reminders increase the probability of owners updating their details on the microchip database, and this could reduce the percentages of stray animals that are unclaimed and subsequently euthanized.

  20. Email Reminders Increase the Frequency That Pet Owners Update Their Microchip Information

    Science.gov (United States)

    Goodwin, Katie; Rand, Jacquie; Morton, John; Uthappa, Varun; Walduck, Rick

    2018-01-01

    Simple Summary Many stray animals presented to shelters in several first world nations have incorrect contact details associated with their microchip and, consequently, cannot be reunited with their owners. This study investigated whether sending email reminders increased the frequency that pet owners updated their contact details on an Australian microchip database, and characterized the cat and dog population on this database. Email reminders were found to be effective at increasing the frequency that pet owners updated their contact details; frequency of updates also varied according to species, pet age, state or territory and socioeconomic differences. The information gained from this study can be used to increase owner compliance in keeping pet microchip contact details up to date, and therefore increase reclaim percentages of stray animals. Abstract Stray animals with incorrect microchip details are less likely to be reclaimed, and unclaimed strays are at increased risk of euthanasia. A retrospective cohort study was performed using 394,747 cats and 904,909 dogs registered with Australia’s largest microchip database to describe animal characteristics, determine whether annual email reminders increased the frequency that owners updated their information, and to compare frequencies of microchip information updates according to pet and owner characteristics. More than twice as many dogs (70%) than cats (30%) were registered on the database; the most numerous pure-breeds were Ragdoll cats and Staffordshire Bull Terrier dogs, and the number of registered animals per capita varied by Australian state or territory. Owners were more likely (p owner updates by state or territory of residence, animal species, animal age, and socioeconomic index of the owner’s postcode. This research demonstrates that email reminders increase the probability of owners updating their details on the microchip database, and this could reduce the percentages of stray animals that are

  1. A systematic review of management strategies for children's mental health care in the emergency department: update on evidence and recommendations for clinical practice and research.

    Science.gov (United States)

    Newton, Amanda S; Hartling, Lisa; Soleimani, Amir; Kirkland, Scott; Dyson, Michele P; Cappelli, Mario

    2017-06-01

    Children with mental health crises require access to specialised resources and services which are not yet standard in general and paediatric EDs. In 2010, we published a systematic review that provided some evidence to support the use of specialised care models to reduce hospitalisation, return ED visits and length of ED stay. We perform a systematic review to update the evidence base and inform current policy statements. Twelve databases and the grey literature were searched up to January 2015. Seven studies were included in the review (four newly identified studies). These studies compared ED-based strategies designed to assess, treat and/or therapeutically support or manage a mental health presentation. The methodological quality of six studies was assessed using the Cochrane Effective Practice and Organization of Care Risk of Bias tool (one interrupted time series study) and a modified Newcastle-Ottawa Scale (three retrospective cohort and two before-after studies). The Grading of Recommendations Assessment, Development and Evaluation (GRADE) system was applied to rate overall evidence quality (high, moderate, low or very low) for individual outcomes from these six studies. An additional study evaluated the psychometric properties of a clinical instrument and was assessed using criteria developed by the Society of Pediatric Psychology Assessment Task Force (well-established, approaching well-established or promising assessment). There is low to very low overall evidence quality that: (1) use of screening laboratory tests to medically clear mental health patients increases length of ED stay and costs, but does not increase the risk of clinical management or disposition change if not conducted; and (2) specialised models of ED care reduce lengths of ED stay, security man-hours and restraint orders. One mental health assessment tool of promising quality, the home, education, activities and peers, drugs and alcohol, suicidality, emotions and behaviour, discharge

  2. Transfinite Numbers

    Indian Academy of Sciences (India)

    Transfinite Numbers. What is Infinity? S M Srivastava. In a series of revolutionary articles written during the last quarter of the nineteenth century, the great Ger- man mathematician Georg Cantor removed the age-old mistrust of infinity and created an exceptionally beau- tiful and useful theory of transfinite numbers. This is.

  3. Advances and Directions for the Intelligent Systems for Geosciences Research Community: Updates and Opportunities from the NSF EarthCube IS-GEO RCN

    Science.gov (United States)

    Pierce, S. A.

    2017-12-01

    The Earthcube Intelligent Systems for Geosciences Research Collaboration Network (IS-GEO RCN) represents an emerging community of interdisciplinary researchers aiming to create fundamental new capabilities for understanding Earth systems. Collaborative efforts across IS-GEO fields of study offer opportunities to accelerate scientific discovery and understanding. The IS-GEO community has an active membership of approximately 65 researchers and includes researchers from across the US, international members, and an early career committee. Current working groups are open to new participants and are focused on four thematic areas with regular coordination meetings and upcoming sessions at professional conferences. (1) The Sensor-based data Collection and Integration Working group looks at techniques for analyzing and integrating of information from heterogeneous sources, with a possible application for early warning systems. (2) The Geoscience Case Studies Working group is creating benchmark data sets to enable new collaborations between geoscientists and data scientists. (3) The Geo-Simulations Working group is evaluating the state of the art in practices for parametrizations, scales, and model integration. (4) The Education Working group is gathering, organizing and collecting all the materials from the different IS-GEO courses. Innovative IS-GEO applications will help researchers overcome common challenges while will redefining the frontiers of discovery across fields and disciplines. (Visit IS-GEO.org for more information or to sign up for any of the working groups.)

  4. Los Alamos Climatology 2016 Update

    Energy Technology Data Exchange (ETDEWEB)

    Bruggeman, David Alan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-02-10

    The Los Alamos National Laboratory (LANL or the Laboratory) operates a meteorology monitoring network to support LANL emergency response, engineering designs, environmental compliance, environmental assessments, safety evaluations, weather forecasting, environmental monitoring, research programs, and environmental restoration. Weather data has been collected in Los Alamos since 1910. Bowen (1990) provided climate statistics (temperature and precipitation) for the 1961– 1990 averaging period, and included other analyses (e.g., wind and relative humidity) based on the available station locations and time periods. This report provides an update to the 1990 publication Los Alamos Climatology (Bowen 1990).

  5. Number theory

    CERN Document Server

    Andrews, George E

    1994-01-01

    Although mathematics majors are usually conversant with number theory by the time they have completed a course in abstract algebra, other undergraduates, especially those in education and the liberal arts, often need a more basic introduction to the topic.In this book the author solves the problem of maintaining the interest of students at both levels by offering a combinatorial approach to elementary number theory. In studying number theory from such a perspective, mathematics majors are spared repetition and provided with new insights, while other students benefit from the consequent simpl

  6. How do we update faces? Effects of gaze direction and facial expressions on working memory updating

    Directory of Open Access Journals (Sweden)

    Caterina eArtuso

    2012-09-01

    Full Text Available The aim of the study was to investigate how the biological binding between different facial dimensions, and their social and communicative relevance, may impact updating processes in working memory (WM. We focused on WM updating because it plays a key role in ongoing processing. Gaze direction and facial expression are crucial and changeable components of face processing. Direct gaze enhances the processing of approach-oriented facial emotional expressions (e.g. joy, while averted gaze enhances the processing of avoidance-oriented facial emotional expressions (e.g. fear. Thus, the way in which these two facial dimensions are combined communicates to the observer important behavioral and social information. Updating of these two facial dimensions and their bindings has not been investigated before, despite the fact that they provide a piece of social information essential for building and maintaining an internal ongoing representation of our social environment. In Experiment 1 we created a task in which the binding between gaze direction and facial expression was manipulated: high binding conditions (e.g. joy-direct gaze were compared to low binding conditions (e.g. joy-averted gaze. Participants had to study and update continuously a number of faces, displaying different bindings between the two dimensions. In Experiment 2 we tested whether updating was affected by the social and communicative value of the facial dimension binding; to this end, we manipulated bindings between eye and hair color, two less communicative facial dimensions. Two new results emerged. First, faster response times were found in updating combinations of facial dimensions highly bound together. Second, our data showed that the ease of the ongoing updating processing varied depending on the communicative meaning of the binding that had to be updated. The results are discussed with reference to the role of WM updating in social cognition and appraisal processes.

  7. How do we update faces? Effects of gaze direction and facial expressions on working memory updating.

    Science.gov (United States)

    Artuso, Caterina; Palladino, Paola; Ricciardelli, Paola

    2012-01-01

    The aim of the study was to investigate how the biological binding between different facial dimensions, and their social and communicative relevance, may impact updating processes in working memory (WM). We focused on WM updating because it plays a key role in ongoing processing. Gaze direction and facial expression are crucial and changeable components of face processing. Direct gaze enhances the processing of approach-oriented facial emotional expressions (e.g., joy), while averted gaze enhances the processing of avoidance-oriented facial emotional expressions (e.g., fear). Thus, the way in which these two facial dimensions are combined communicates to the observer important behavioral and social information. Updating of these two facial dimensions and their bindings has not been investigated before, despite the fact that they provide a piece of social information essential for building and maintaining an internal ongoing representation of our social environment. In Experiment 1 we created a task in which the binding between gaze direction and facial expression was manipulated: high binding conditions (e.g., joy-direct gaze) were compared to low binding conditions (e.g., joy-averted gaze). Participants had to study and update continuously a number of faces, displaying different bindings between the two dimensions. In Experiment 2 we tested whether updating was affected by the social and communicative value of the facial dimension binding; to this end, we manipulated bindings between eye and hair color, two less communicative facial dimensions. Two new results emerged. First, faster response times were found in updating combinations of facial dimensions highly bound together. Second, our data showed that the ease of the ongoing updating processing varied depending on the communicative meaning of the binding that had to be updated. The results are discussed with reference to the role of WM updating in social cognition and appraisal processes.

  8. The European Organization for Research and Treatment of Cancer approach to developing questionnaire modules: an update and overview. EORTC Quality of Life Study Group

    NARCIS (Netherlands)

    Sprangers, M. A.; Cull, A.; Groenvold, M.; Bjordal, K.; Blazeby, J.; Aaronson, N. K.

    1998-01-01

    The European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Study Group has adopted a modular approach to quality of life (QoL) assessment in cancer clinical trials. The core instrument (the EORTC QLQ-C30) covers a range of QoL issues relevant to a broad spectrum of

  9. News at Biochemia Medica: research integrity corner, updated guidelines to authors, revised author statement form and adopted ICMJE Conflict-of-Interest Form.

    Science.gov (United States)

    Simundic, Ana-Maria

    2013-01-01

    From the issue 23(1) we have implemented several major changes in the editorial policies and procedures. We hope that those changes will raise awareness of our potential authors and reviewers for research and publication integrity issues as well as to improve the quality of our submissions and published articles. Among those changes is the launch of a special journal section called Research Integrity Corner. In this section we aim to publish educational articles dealing with different research and publication misconduct issues. Moreover, we have done a comprehensive revision of our Instructions to authors. Whereas our former Instructions to authors have mostly been concerned with recommendations for manuscript preparation and submission, the revised document additionally describes the editorial procedure for all submitted articles and provides exact journal policies towards research integrity, authorship, copyright and conflict of interest. By putting these Guidelines into action, we hope that our main ethical policies and requirements are now visible and available to all our potential authors. We have also revised the former Authorship and copyright form which is now called the Author statement form. This form now contains statements on the authorship, originality of work, research ethics, patient privacy and confidentiality, and copyright transfer. Finally, Journal has adopted the ICMJE Form for Disclosure of Potential Conflicts of Interest. From this issue, for each submitted article, authors are requested to fill out the "ICMJE Form for Disclosure of Potential Conflicts of Interest" as well as the Author statement form and upload those forms during the online manuscript submission process. We honestly believe that our authors and readers will appreciate such endeavors. In this Editorial article we briefly explain the background and the nature of those recent major editorial changes.

  10. Nice numbers

    CERN Document Server

    Barnes, John

    2016-01-01

    In this intriguing book, John Barnes takes us on a journey through aspects of numbers much as he took us on a geometrical journey in Gems of Geometry. Similarly originating from a series of lectures for adult students at Reading and Oxford University, this book touches a variety of amusing and fascinating topics regarding numbers and their uses both ancient and modern. The author intrigues and challenges his audience with both fundamental number topics such as prime numbers and cryptography, and themes of daily needs and pleasures such as counting one's assets, keeping track of time, and enjoying music. Puzzles and exercises at the end of each lecture offer additional inspiration, and numerous illustrations accompany the reader. Furthermore, a number of appendices provides in-depth insights into diverse topics such as Pascal’s triangle, the Rubik cube, Mersenne’s curious keyboards, and many others. A theme running through is the thought of what is our favourite number. Written in an engaging and witty sty...

  11. Early Limits on the Verbal Updating of an Object's Location

    Science.gov (United States)

    Ganea, Patricia A.; Harris, Paul L.

    2013-01-01

    Recent research has shown that by 30 months of age, children can successfully update their representation of an absent object's location on the basis of new verbal information, whereas 23-month-olds often return to the object's prior location. The current results show that this updating failure persisted even when (a) toddlers received visual and…

  12. Updating action domain descriptions.

    Science.gov (United States)

    Eiter, Thomas; Erdem, Esra; Fink, Michael; Senko, Ján

    2010-10-01

    Incorporating new information into a knowledge base is an important problem which has been widely investigated. In this paper, we study this problem in a formal framework for reasoning about actions and change. In this framework, action domains are described in an action language whose semantics is based on the notion of causality. Unlike the formalisms considered in the related work, this language allows straightforward representation of non-deterministic effects and indirect effects of (possibly concurrent) actions, as well as state constraints; therefore, the updates can be more general than elementary statements. The expressivity of this formalism allows us to study the update of an action domain description with a more general approach compared to related work. First of all, we consider the update of an action description with respect to further criteria, for instance, by ensuring that the updated description entails some observations, assertions, or general domain properties that constitute further constraints that are not expressible in an action description in general. Moreover, our framework allows us to discriminate amongst alternative updates of action domain descriptions and to single out a most preferable one, based on a given preference relation possibly dependent on the specified criteria. We study semantic and computational aspects of the update problem, and establish basic properties of updates as well as a decomposition theorem that gives rise to a divide and conquer approach to updating action descriptions under certain conditions. Furthermore, we study the computational complexity of decision problems around computing solutions, both for the generic setting and for two particular preference relations, viz. set-inclusion and weight-based preference. While deciding the existence of solutions and recognizing solutions are PSPACE-complete problems in general, the problems fall back into the polynomial hierarchy under restrictions on the additional

  13. BI-RADS update.

    Science.gov (United States)

    Mercado, Cecilia L

    2014-05-01

    The updated American College of Radiology (ACR) Breast Imaging Reporting and Data System (BI-RADS) has been newly released. This article summarizes the changes and updates that have been made to BI-RADS. The goal of the revised edition continues to be the same: to improve clarification in image interpretation, maintain reporting standardization, and simplify the monitoring of outcomes. The new BI-RADS also introduces new terminology to provide a more universal lexicon across all 3 imaging modalities. Copyright © 2014 Elsevier Inc. All rights reserved.

  14. 2014 Update of the Canadian Rheumatology Association/spondyloarthritis research consortium of Canada treatment recommendations for the management of spondyloarthritis. Part I: principles of the management of spondyloarthritis in Canada.

    Science.gov (United States)

    Rohekar, Sherry; Chan, Jon; Tse, Shirley M L; Haroon, Nigil; Chandran, Vinod; Bessette, Louis; Mosher, Dianne; Flanagan, Cathy; Keen, Kevin J; Adams, Karen; Mallinson, Michael; Thorne, Carter; Rahman, Proton; Gladman, Dafna D; Inman, Robert D

    2015-04-01

    The Canadian Rheumatology Association (CRA) and the Spondyloarthritis Research Consortium of Canada (SPARCC) have collaborated to update the recommendations for the management of spondyloarthritis (SpA). A working group was assembled and consisted of the SPARCC executive committee, rheumatologist leaders from SPARCC collaborating sites, Canadian rheumatologists from across the country with an interest in SpA (both academic and community), a rheumatology trainee with an interest in SpA, an epidemiologist/health services researcher, a member of the CRA executive, a member of the CRA therapeutics committee, and a patient representative from the Canadian Spondylitis Association. An extensive review was conducted of literature published from 2007 to 2014 involving the management of SpA. The working group created draft recommendations using multiple rounds of Web-based surveys and an in-person conference. A survey was sent to the membership of the CRA to obtain an extended review that was used to finalize the recommendations. Guidelines for the management of SpA were created. Part I focuses on the principles of management of SpA in Canada and includes 6 general management principles, 5 ethical considerations, target groups for treatment recommendations, 2 wait time recommendations, and recommendations for disease monitoring. Also included are 6 modifications for application to juvenile SpA. These recommendations were developed based on current literature and applied to a Canadian healthcare context. It is hoped that the implementation of these recommendations will promote best practices in the treatment of SpA.

  15. Funny Numbers

    Directory of Open Access Journals (Sweden)

    Theodore M. Porter

    2012-12-01

    Full Text Available The struggle over cure rate measures in nineteenth-century asylums provides an exemplary instance of how, when used for official assessments of institutions, these numbers become sites of contestation. The evasion of goals and corruption of measures tends to make these numbers “funny” in the sense of becoming dis-honest, while the mismatch between boring, technical appearances and cunning backstage manipulations supplies dark humor. The dangers are evident in recent efforts to decentralize the functions of governments and corporations using incen-tives based on quantified targets.

  16. Important update of CERN Mail Services

    CERN Document Server

    IT Department

    2009-01-01

    The CERN Mail Services are evolving. In the course of June and July 2009, all CERN mailboxes will be updated with a new infrastructure for hosting mailboxes, running Exchange 2007. This update is taking place in order to provide the capacity upgrade for the constantly growing volume of CERN mailboxes. It is also the opportunity to provide a number of improvements to CERN mailboxes: new and improved Outlook Web Access (the web interface used to access your mailbox from a web browser, also known as "webmail"), new features in the Out-of-Office auto-reply assistant, easier spam management... The update will preserve the mailbox configuration and no specific action is required by users. During the next weeks, each mailbox will be individually notified of the upcoming update the day before it takes place. We invite all users to carefully read this notification as it will contain the latest information for this update. The mailbox will be unavailable for a short time during the ni...

  17. Fundamental number theory with applications

    CERN Document Server

    Mollin, Richard A

    2008-01-01

    An update of the most accessible introductory number theory text available, Fundamental Number Theory with Applications, Second Edition presents a mathematically rigorous yet easy-to-follow treatment of the fundamentals and applications of the subject. The substantial amount of reorganizing makes this edition clearer and more elementary in its coverage. New to the Second Edition           Removal of all advanced material to be even more accessible in scope           New fundamental material, including partition theory, generating functions, and combinatorial number theory           Expa

  18. Transportation and Aging: An Updated Research Agenda to Advance Safe Mobility among Older Adults Transitioning From Driving to Non-driving.

    Science.gov (United States)

    Dickerson, Anne E; Molnar, Lisa J; Bédard, Michel; Eby, David W; Berg-Weger, Marla; Choi, Moon; Grigg, Jenai; Horowitz, Amy; Meuser, Thomas; Myers, Anita; O'Connor, Melissa; Silverstein, Nina M

    2017-07-29

    Engagement in civic, social, and community life plays an important role in health, well-being, and quality of life, and requires individuals to be mobile in their environment. In this article, we review what is currently known about 2 areas relevant to safe mobility for older drivers and identify future research in these areas. Using a framework for transportation and safe mobility, 2 key areas were selected for review: the process of transitioning to non-driving and the maintenance of mobility after driving has ceased. This article serves as a companion to another article that used the same approach to explore safe mobility issues for older adults who are still driving. We found that although there has been progress in supporting transitioning process to non-driving and improving mobility options for older adults following driving cessation, many knowledge gaps still exist. We identified several research topics that would benefit from continued scientific inquiry. In addition, several themes emerged from the review, including the need for: multidisciplinary, community-wide solutions; large-scale, longitudinal studies; improved education and training for older adults and the variety of stakeholders involved in older adult transportation; and the need for programs and interventions that are flexible and responsive to individual needs and situational differences. © The Author 2017. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  19. Number Guessing

    Science.gov (United States)

    Sezin, Fatin

    2009-01-01

    It is instructive and interesting to find hidden numbers by using different positional numeration systems. Most of the present guessing techniques use the binary system expressed as less-than, greater-than or present-absent type information. This article describes how, by employing four cards having integers 1-64 written in different colours, one…

  20. Transfinite Numbers

    Indian Academy of Sciences (India)

    this is a characteristic difference between finite and infinite sets and created an immensely useful branch of mathematics based on this idea which had a great impact on the whole of mathe- matics. For example, the question of what is a number (finite or infinite) is almost a philosophical one. However Cantor's work turned it ...

  1. Transfinite Numbers

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 3. Transfinite Numbers - What is Infinity? S M Srivastava. General Article Volume 2 Issue 3 March 1997 pp 58-68. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/002/03/0058-0068 ...

  2. Liver Transplantation Update: 2014.

    Science.gov (United States)

    Dogan, Serkan; Gurakar, Ahmet

    2015-01-01

    The first liver transplantation (LT) was performed by Thomas E Starzl five decades ago, and yet it remains the only therapeutic option offering gold standard treatment for end-stage liver disease (ESLD) and acute liver failure (ALF) and certain early-stage liver tumors. Post-liver transplantation survival has also dramatically improved over the last few decades despite increasing donor and recipient age and more frequent use of marginal organs to overcome the organ shortage. Currently, the overall 1 year survival following LT in the United States is reported as 85 to 90%, while the 10 years survival rate is ~50% (http://www.unos.org). The improvements are mainly due to progress in surgical techniques, postoperative intensive care, and the advent of new immunosuppressive agents. There are a number of factors that influence the outcomes prior to transplantation. Since 2002, the model for end-stage liver disease (MELD) score has been considered a predicting variable. It has been used to prioritize patients on the transplant waiting list and is currently the standard method used to assess severity in all etiologies of cirrhosis. Hepatocellular carcinoma (HCC) is the most common standard MELD exception because the MELD does not necessarily reflect the medical urgency of patients with HCC. The criteria for candidates with HCC for receiving LT have evolved over the past decade. Now, patients with HCC who do not meet the traditional Milan (MC) or UCSF criteria for LT often undergo downstaging therapy I an effort to shrink the tumor size. The shortage of donor organs is a universal problem. In some countries, the development of a deceased organ donation program has been prevented due to socioeconomic, cultural, legal and other factors. Due to the shortage of cadaveric donors, several innovative techniques have been developed to expand the organ donor pool, such as split liver grafts, marginal- or extended-criteria donors, live donor liver transplantation (LDLT), and the use

  3. Internet Journal of Medical Update - EJOURNAL

    African Journals Online (AJOL)

    Internet Journal of Medical Update (IJMU) is an international e-journal which provides a multidisciplinary forum for the exchange of current ideas in form of review articles, original research work, interesting case reports, etc. among medical professionals. Editorial policy: The Editor receives manuscripts with the ...

  4. Invasive Species Science Update (No. 1)

    Science.gov (United States)

    Mee-Sook Kim; Jack Butler

    2008-01-01

    This electronic newsletter (Invasive Species Science Update) is published by the Rocky Mountain Research Station (RMRS) Cross-Program, Interdisciplinary Project team on Invasive Species. This newsletter will be published 3 times per year and is intended to enhance communication among RMRS scientists, wildland managers, other partners, stakeholders, and customers about...

  5. Invasive Species Science Update (No. 7)

    Science.gov (United States)

    Dean Pearson; Yvette Ortega; Jack Butler

    2014-01-01

    Invasive Species Science Updates are designed to keep managers and other users up-to-date with recently completed and ongoing research by RMRS scientists, as well as highlight breaking news related to invasive species issues. The newsletter is produced by the RMRS Invasive Species Working Group (ISWG), which is a core group of scientists who volunteer to coordinate...

  6. Invasive Species Science Update (No. 5)

    Science.gov (United States)

    Dean Pearson; Yvette Ortega

    2011-01-01

    Welcome to the fifth issue of the Rocky Mountain Research Station's (RMRS) Invasive Species Science Update. The newsletter is produced by the RMRS Invasive Species Working Group (ISWG), which is a core group of scientists who volunteer to coordinate outreach of RMRS invasive species science to managers and the public. After publishing the past four newsletters, we...

  7. Invasive Species Science Update (No. 8)

    Science.gov (United States)

    Dean Pearson; Yvette Ortega; Jack Butler

    2015-01-01

    Invasive Species Science Updates are designed to keep managers and other users up-to-date with recently completed and ongoing research by RMRS scientists, as well as highlight breaking news related to invasive species issues. The newsletter is produced by the RMRS Invasive Species Working Group (ISWG), which is a core group of scientists who volunteer to coordinate...

  8. [WWW.2CHEAT.COM] Update

    Science.gov (United States)

    Rooks, Clay D.

    2006-01-01

    This paper is an updated presentation on the subject of cheating and plagiarism via the World Wide Web. In a few hours searching the Internet, the author found even more "cheat" sites than in 1998 that offered not only all types of term and research papers, but college admission letters, reviews, case studies, even dissertations as well. Most now…

  9. An update to the Surface Ocean CO

    NARCIS (Netherlands)

    Bakker, D.C.E.; de Baar, H.J.W.; van heuven, S.

    2014-01-01

    The Surface Ocean CO2 Atlas (SOCAT), an activity of the international marine carbon research community, provides access to synthesis and gridded fCO2 (fugacity of carbon dioxide) products for the surface oceans. Version 2 of SOCAT is an update of the previous release (version

  10. Supreme Court Update

    Science.gov (United States)

    Taylor, Kelley R.

    2009-01-01

    "Chief Justice Flubs Oath." "Justice Ginsburg Has Cancer Surgery." At the start of this year, those were the news headlines about the U.S. Supreme Court. But January 2009 also brought news about key education cases--one resolved and two others on the docket--of which school administrators should take particular note. The Supreme Court updates on…

  11. Update: Biological Nitrogen Fixation.

    Science.gov (United States)

    Wiseman, Alan; And Others

    1985-01-01

    Updates knowledge on nitrogen fixation, indicating that investigation of free-living nitrogen-fixing organisms is proving useful in understanding bacterial partners and is expected to lead to development of more effective symbioses. Specific areas considered include biochemistry/genetics, synthesis control, proteins and enzymes, symbiotic systems,…

  12. Liver transplantation : an update

    NARCIS (Netherlands)

    Verdonk, R. C.; Van den Berg, A. P.; Slooff, M. J. H.; Porte, R. J.; Haagsma, E. B.

    2007-01-01

    Liver transplantation has been an accepted treatment for end-stage liver disease since the 1980s. Currently it is a highly successful treatment for this indication. The aim of this review is to give a general update on recent developments in the field of liver transplantation. In the last decades

  13. Phaeochromocytoma – an update

    African Journals Online (AJOL)

    but has been advocated as the test of choice in many studies. The management of a phaeochromocytoma is mainly surgical and requires careful patient preparation to avoid catecholamine-induced complications during surgery. This review provides an update on phaeochromocytomas. Genetics. 68. J e. MDS a. November ...

  14. Updating protocols prodigy.

    Science.gov (United States)

    Ambrose, Kate

    2005-04-01

    If you are updating protocols, why not try the Prodigy website, at www.prodigy.nhs.uk ? It is a source of clinical knowledge on a range oftopics that is based on best evidence and organised to support clinical decision making.

  15. Update of telephone exchange

    CERN Multimedia

    2006-01-01

    As part of the upgrade of telephone services, the CERN switching centre will be updated on Monday 3 July between 8.00 p.m. and 3.00 a.m. Telephone services may be disrupted and possibly even interrupted during this operation.We apologise in advance for any inconvenience this may cause. CERN TELECOM Service

  16. Update of telephone exchange

    CERN Multimedia

    2006-01-01

    As part of the upgrade of telephone services, the CERN switching centre will be updated on between Monday 23 October 8.00 p.m. and Tuesday 24 October 2.00 a.m. Telephone services may be disrupted and possibly even interrupted during this operation. We apologise in advance for any inconvenience this may cause. CERN TELECOM Service

  17. Update of telephone exchange

    CERN Multimedia

    2006-01-01

    As part of the upgrade of telephone services, the CERN switching centre will be updated on Monday 3 July between 8.00 p.m. and 3.00 a.m. Telephone services may be disrupted and possibly even interrupted during this operation. We apologise in advance for any inconvenience this may cause. CERN TELECOM Service

  18. Update of telephone exchange

    CERN Multimedia

    2006-01-01

    As part of the upgrade of telephone services, the CERN switching centre will be updated on Wednesday 14 June between 8.00 p.m. and midnight. Telephone services may be disrupted and possibly even interrupted during this operation. We apologise in advance for any inconvenience this may cause. CERN TELECOM Service

  19. The economic importance of acaricides in the control of phytophagous mites and an update on recent acaricide mode of action research.

    Science.gov (United States)

    Van Leeuwen, Thomas; Tirry, Luc; Yamamoto, Atsushi; Nauen, Ralf; Dermauw, Wannes

    2015-06-01

    Acaricides are one of the cornerstones of an efficient control program for phytophagous mites. An analysis of the global acaricide market reveals that spider mites such as Tetranychus urticae, Panonychus citri and Panonychus ulmi are by far the most economically important species, representing more than 80% of the market. Other relevant mite groups are false spider mites (mainly Brevipalpus), rust and gall mites and tarsonemid mites. Acaricides are most frequently used in vegetables and fruits (74% of the market), including grape vines and citrus. However, their use is increasing in major crops where spider mites are becoming more important, such as soybean, cotton and corn. As revealed by a detailed case study of the Japanese market, major shifts in acaricide use are partially driven by resistance development and the commercial availability of compounds with novel mode of action. The importance of the latter cannot be underestimated, although some compounds are successfully used for more than 30 years. A review of recent developments in mode of action research is presented, as such knowledge is important for devising resistance management programs. This includes spirocyclic keto-enols as inhibitors of acetyl-CoA carboxylase, the carbazate bifenazate as a mitochondrial complex III inhibitor, a novel class of complex II inhibitors, and the mite growth inhibitors hexythiazox, clofentezine and etoxazole that interact with chitin synthase I. Copyright © 2014 Elsevier Inc. All rights reserved.

  20. An industry update: the latest news in therapeutic delivery.

    Science.gov (United States)

    Harris, Elaine

    2017-11-01

    The present industry update covers the period 1-31 July 2017. Information was sourced primarily from company press releases, regulatory and patent agencies, scientific literature and various news websites. There was positive approval news this month for GlaxoSmithKline for its new self-injecting treatment for systemic lupus erythematosus but less positive news for Ocular Therapeutix, a new drug application for its treatment for postoperative ocular pain, DEXTENZA™ was rejected for a second time. Endo Pharmaceuticals agreed to withdraw its opioid formulation Opana ® Er due to abuse concerns. Collaborations for novel therapeutic delivery research were announced this month by Takeda and BioSurfaces, Catelent and Rutgers University, Lilly and Purdue University and Titan Pharmaceuticals with Walter Reed and the Southwest Research Institute. A number of companies announced significant financing deals to allow for the clinical development of products with enhanced delivery options including Sebacia and Diasome.

  1. 78 FR 68849 - Draft Current Intelligence Bulletin “Update of NIOSH Carcinogen Classification and Target Risk...

    Science.gov (United States)

    2013-11-15

    ..., benzene, and others. Further, the existing NIOSH carcinogen policy does not allow for classification on...; Docket Number NIOSH 240-A] Draft Current Intelligence Bulletin ``Update of NIOSH Carcinogen... document for public comment entitled ``Current Intelligence Bulletin: Update of NIOSH Carcinogen...

  2. 78 FR 9743 - Advisory Committee for Environmental Research and Education; Notice of Meeting

    Science.gov (United States)

    2013-02-11

    ... NATIONAL SCIENCE FOUNDATION Advisory Committee for Environmental Research and Education; Notice of... concerning support for environmental research and education. Agenda March 13, 2013 Update on NSF environmental research and education activities Update on national and international collaborations Update on...

  3. Pilot Scale Integrated Biorefinery for Producing Ethanol from Hybrid Algae: Cooperative Research and Development Final Report, CRADA Number CRD-10-389

    Energy Technology Data Exchange (ETDEWEB)

    Pienkos, P. T.

    2013-11-01

    This collaboration between Algenol Biofuels Inc. and NREL will provide valuable information regarding Direct to Ethanol technology. Specifically, the cooperative R&D will analyze the use of flue gas from industrial sources in the Direct to Ethanol process, which may demonstrate the potential to significantly reduce greenhouse gas emissions while simultaneously producing a valuable product, i.e., ethanol. Additionally, Algenol Biofuels Inc. and NREL will develop both a techno-economic model with full material and energy balances and an updated life-cycle analysis to identify greenhouse gas emissions relative to gasoline, each of which will provide a better understanding of the Direct to Ethanol process and further demonstrate that it is a breakthrough technology with varied and significant benefits.

  4. 21 CFR 807.30 - Updating device listing information.

    Science.gov (United States)

    2010-04-01

    ... identification number, the classification name and number, the proprietary name, and the common or usual name of... operator name or number, e.g., whenever one company's device line is purchased by another owner or operator... since the previously submitted list. Also, updating is not required if changes occur in proprietary...

  5. High Reynolds Number Turbulence

    National Research Council Canada - National Science Library

    Smits, Alexander J

    2007-01-01

    The objectives of the grant were to provide a systematic study to fill the gap between existing research on low Reynolds number turbulent flows to the kinds of turbulent flows encountered on full-scale vehicles...

  6. Sequence History Update Tool

    Science.gov (United States)

    Khanampompan, Teerapat; Gladden, Roy; Fisher, Forest; DelGuercio, Chris

    2008-01-01

    The Sequence History Update Tool performs Web-based sequence statistics archiving for Mars Reconnaissance Orbiter (MRO). Using a single UNIX command, the software takes advantage of sequencing conventions to automatically extract the needed statistics from multiple files. This information is then used to populate a PHP database, which is then seamlessly formatted into a dynamic Web page. This tool replaces a previous tedious and error-prone process of manually editing HTML code to construct a Web-based table. Because the tool manages all of the statistics gathering and file delivery to and from multiple data sources spread across multiple servers, there is also a considerable time and effort savings. With the use of The Sequence History Update Tool what previously took minutes is now done in less than 30 seconds, and now provides a more accurate archival record of the sequence commanding for MRO.

  7. Ontario Hydro's DSP update

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    Ontario Hydro's Demand/Supply Plan (DSP), the 25 year plan which was submitted in December 1989, is currently being reviewed by the Environmental Assessment Board (EAB). Since 1989 there have been several changes which have led Ontario Hydro to update the original Demand/Supply Plan. This information sheet gives a quick overview of what has changed and how Ontario Hydro is adapting to that change

  8. Strategies for Successful Aging: A Research Update

    Science.gov (United States)

    Depp, Colin A.; Harmell, Alexandrea L.; Jeste, Dilip

    2014-01-01

    Population aging is an enormous public health issue and there is clear need for strategies to maximize opportunities for successful aging. Many psychiatric illnesses are increasingly thought to be associated with accelerated aging, therefore emerging data on individual and policy level interventions that alter typical aging trajectories are relevant to mental health practitioners. Although the determinants and definition of successful aging remain controversial, increasing data indicate that psychiatric illnesses directly impact biological aging trajectories and diminish lifestyle, psychological and socio-environmental factors that seem reduce risk of morbidity and mortality. Many interventions designed to enhance the normal course of aging may be adjunctive approaches to management of psychiatric illnesses. We highlight recent data on interventions seeking to promote healthy aging, such as cognitive remediation, physical activity, nutrition, and complementary and alternative treatments for older people with and without psychiatric illnesses. PMID:25135776

  9. Avian Disease & Oncology Lab (ADOL) Research Update

    Science.gov (United States)

    Employing Genomics, Epigenetics, and Immunogenetics to Control Diseases Induced by Avian Tumor Viruses - Gene expression is a major factor accounting for phenotypic variation. Taking advantage of allele-specific expression (ASE) screens, we found the use of genetic markers was superior to traditiona...

  10. Research Update: Luminescence in lead halide perovskites

    Directory of Open Access Journals (Sweden)

    Ajay Ram Srimath Kandada

    2016-09-01

    Full Text Available Efficiency and dynamics of radiative recombination of carriers are crucial figures of merit for optoelectronic materials. Following the recent success of lead halide perovskites in efficient photovoltaic and light emitting technologies, here we review some of the noted literature on the luminescence of this emerging class of materials. After outlining the theoretical formalism that is currently used to explain the carrier recombination dynamics, we review a few significant works which use photoluminescence as a tool to understand and optimize the operation of perovskite based optoelectronic devices.

  11. Research Update: Luminescence in lead halide perovskites

    Science.gov (United States)

    Srimath Kandada, Ajay Ram; Petrozza, Annamaria

    2016-09-01

    Efficiency and dynamics of radiative recombination of carriers are crucial figures of merit for optoelectronic materials. Following the recent success of lead halide perovskites in efficient photovoltaic and light emitting technologies, here we review some of the noted literature on the luminescence of this emerging class of materials. After outlining the theoretical formalism that is currently used to explain the carrier recombination dynamics, we review a few significant works which use photoluminescence as a tool to understand and optimize the operation of perovskite based optoelectronic devices.

  12. Update on abusive head trauma.

    Science.gov (United States)

    Shaahinfar, Ashkon; Whitelaw, Kevin D; Mansour, Karim M

    2015-06-01

    This article provides an update on abusive head trauma (AHT), focusing on new developments most salient to the emergency medicine clinician, including epidemiology, clinical recognition, diagnostic work-up, management of neurologic injury, and public health implications. The recent literature has focused on honing the clinician's ability to recognize AHT and its immediate sequelae, to more accurately distinguish between abusive and accidental head injuries by patterns of neuroimaging and retinal hemorrhages, and to appreciate the long-term impacts. Specifically, both a clinical prediction rule and biomarker show promise, and new research advocates for the early identification of subclinical seizures as well as cervical spine injuries. The emergency medicine provider must be able to recognize and manage children who may have AHT and to appreciate when the diagnostic findings warrant consultation with a child protection team. These authors summarize the recent and notable advances in our understanding of AHT.

  13. Perancangan Sistem Otomatis Update Pada Aplikasi Desktop Abios

    Directory of Open Access Journals (Sweden)

    Karto Iskandar

    2010-12-01

    Full Text Available Unlike web applications easier to update the latest version, desktop applications more difficult and must involve the user in doing so. It is caused by a desktop application is an application that is installed in the computer user. The purpose of this research is to design an automatic system updates on a desktop application, an example case: Application Binus International Operational Support (ABIOS. This research used literature study and system design. In desktop applications, often there is update the latest applications that are not known to the user who sometimes fatal and disrupt business operations. Generally, developer will inform the changes version to user that they can update the application. In an update of applications, should be done by the system automatically, not manually by users. Once in a while, the user background is not from computer base. After doing the research, it can be concluded that the system automatically updates the application has benefits to users in obtaining information regarding the latest version, and can assist in automatically update the latest application is based on computerization. For further development of this system is expected to operate on multi platforms and or mobile applications. 

  14. Updated Colors for Cool Stars in the SDSS

    OpenAIRE

    West, Andrew A.; Walkowicz, Lucianne M.; Hawley, Suzanne L.

    2005-01-01

    We present updated colors for M and L dwarfs based on photometry from the third data release of the Sloan Digital Sky Survey (SDSS). These data are improved in quality and number from earlier results. We also provide updated equations for determining photometric parallaxes from SDSS colors of late-type stars. Walkowicz, Hawley & West (2004) have recently presented new techniques for studying the magnetic activity of low-mass stars and their method relies on an accurate determination of SDSS c...

  15. Experimental research on the contrast production of the chemical elements with the atomic numbers 1-83 in a computer-totalbody-tomogram

    International Nuclear Information System (INIS)

    Kirschner, H.; Burmester, U.; Stringaris, K.

    1979-01-01

    The contrast production for the chemical elements with the atomic numbers Z=1-83 were determined by computer-tomography. With the formula relation of the Δ-number and the atomic number can one compute the contrast production of any chosen chemical compound. Iodine-free and inorganic iodine-containing contrast media are examined for their contrast production and compared with presently used organic iodine-containing contrast media. The contrast enhancement of organic contrast media in tissue are discussed. (orig.) [de

  16. 2016 update of the PRIDE database and its related tools.

    Science.gov (United States)

    Vizcaíno, Juan Antonio; Csordas, Attila; del-Toro, Noemi; Dianes, José A; Griss, Johannes; Lavidas, Ilias; Mayer, Gerhard; Perez-Riverol, Yasset; Reisinger, Florian; Ternent, Tobias; Xu, Qing-Wei; Wang, Rui; Hermjakob, Henning

    2016-01-04

    The PRoteomics IDEntifications (PRIDE) database is one of the world-leading data repositories of mass spectrometry (MS)-based proteomics data. Since the beginning of 2014, PRIDE Archive (http://www.ebi.ac.uk/pride/archive/) is the new PRIDE archival system, replacing the original PRIDE database. Here we summarize the developments in PRIDE resources and related tools since the previous update manuscript in the Database Issue in 2013. PRIDE Archive constitutes a complete redevelopment of the original PRIDE, comprising a new storage backend, data submission system and web interface, among other components. PRIDE Archive supports the most-widely used PSI (Proteomics Standards Initiative) data standard formats (mzML and mzIdentML) and implements the data requirements and guidelines of the ProteomeXchange Consortium. The wide adoption of ProteomeXchange within the community has triggered an unprecedented increase in the number of submitted data sets (around 150 data sets per month). We outline some statistics on the current PRIDE Archive data contents. We also report on the status of the PRIDE related stand-alone tools: PRIDE Inspector, PRIDE Converter 2 and the ProteomeXchange submission tool. Finally, we will give a brief update on the resources under development 'PRIDE Cluster' and 'PRIDE Proteomes', which provide a complementary view and quality-scored information of the peptide and protein identification data available in PRIDE Archive. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  17. Web Browser Security Update Effectiveness

    Science.gov (United States)

    Duebendorfer, Thomas; Frei, Stefan

    We analyze the effectiveness of different Web browser update mechanisms on various operating systems; from Google Chrome's silent update mechanism to Opera's update requiring a full re-installation. We use anonymized logs from Google's world wide distributed Web servers. An analysis of the logged HTTP user-agent strings that Web browsers report when requesting any Web page is used to measure the daily browser version shares in active use. To the best of our knowledge, this is the first global scale measurement of Web browser update effectiveness comparing four different Web browser update strategies including Google Chrome. Our measurements prove that silent updates and little dependency on the underlying operating system are most effective to get users of Web browsers to surf the Web with the latest browser version.

  18. An update on magnesium homeostasis mechanisms in plants.

    Science.gov (United States)

    Hermans, Christian; Conn, Simon J; Chen, Jiugeng; Xiao, Qiying; Verbruggen, Nathalie

    2013-09-01

    Worldwide, nearly two-thirds of the population do not consume the recommended amount of magnesium (Mg) in their diet. Furthermore, low Mg status (hypomagnesaemia) is known to contribute to a number of human chronic disease conditions. Because the principal dietary Mg source is of plant origin, agronomic and genetic biofortification strategies are aimed at improving nutritional Mg content in food crops to overcome this mineral deficiency in humans. This update incorporates the contributions of annotated permeases involved in Mg uptake, storage and recycling with a schematic model of Mg movement at the organ and cellular levels in the model species Arabidopsis thaliana. Furthermore, approaches using mutagenesis or natural ionomic variation to identify loci involved in Mg homeostasis in roots, leaves and seeds will be summarised. A brief overview will be presented on how Arabidopsis research can help to develop strategies for biofortification of crops.

  19. Radiotherapy: An Update

    Directory of Open Access Journals (Sweden)

    Vikrant Kasat

    2010-01-01

    Full Text Available Radiotherapy is the art of using ionizing radiation to destroy malignant cells while minimizing damage to normal tissue. Radiotherapy has become a standard treatment option for a wide range of malignancies. Several new imaging techniques, both anatomical and functional are currently being evaluated as well as practiced for treatment planning of cancer. These recent developments have allowed radiation oncologists to escalate the dose of radiation delivered to tumors while minimizing the dose delivered to surrounding normal tissue. In this update, we attempt to pen down important aspects of radiotherapy.

  20. Hypokalemia: a clinical update

    Directory of Open Access Journals (Sweden)

    Efstratios Kardalas

    2018-04-01

    Full Text Available Hypokalemia is a common electrolyte disturbance, especially in hospitalized patients. It can have various causes, including endocrine ones. Sometimes, hypokalemia requires urgent medical attention. The aim of this review is to present updated information regarding: (1 the definition and prevalence of hypokalemia, (2 the physiology of potassium homeostasis, (3 the various causes leading to hypokalemia, (4 the diagnostic steps for the assessment of hypokalemia and (5 the appropriate treatment of hypokalemia depending on the cause. Practical algorithms for the optimal diagnostic, treatment and follow-up strategy are presented, while an individualized approach is emphasized.

  1. Context updates are hierarchical

    Directory of Open Access Journals (Sweden)

    Anton Karl Ingason

    2016-10-01

    Full Text Available This squib studies the order in which elements are added to the shared context of interlocutors in a conversation. It focuses on context updates within one hierarchical structure and argues that structurally higher elements are entered into the context before lower elements, even if the structurally higher elements are pronounced after the lower elements. The crucial data are drawn from a comparison of relative clauses in two head-initial languages, English and Icelandic, and two head-final languages, Korean and Japanese. The findings have consequences for any theory of a dynamic semantics.

  2. ASDSO updates bibliography, creates support database

    International Nuclear Information System (INIS)

    Spragens, L.

    1993-01-01

    The Association of State Dam Safety Officials has updated its Bibliography of Dam Safety Practices, originally published in 1990 with assistance from the US Committee on Large Dams. The new document lists publications addressing dam safety issues and includes 20 subject headings. The Federal Emergency Management Agency underwrote the update, which includes information about journal articles on dam safety, conference presentations, and new books and manuals. The publication also contains information about obtaining copies of the documents. The bibliography features a new section on use of geosynthetics in dam safety, compiled by Greg Hammer, of ASDSO's Technical Committee. Dam break analysis, emergency action planning, instrumentation, inspections, overtopping of dams, rehabilitation of dams, risk analysis, and seismic behavior are also included. In conjunction with the release of the updated bibliography, ASDSO is creating a computer database for its members that contains information from the bibliography. ASDSO also is in the process of adding information to the database about current research in dam safety. When the database becomes available later this year, members will be able to search for information on research in a specific subject area. Users also will be able to search for research groups, individuals, and universities to obtain an overview of who is conducting research in dam safety. Additionally, the database will allow the user to search for subject matter experts when looking for conference speakers and writers with specific specialties

  3. Journal of research of the national institute of standards and technology, January-February 1993. Volume 98, Number 1. Special issue

    International Nuclear Information System (INIS)

    1993-01-01

    Contents: The NIST Cold Neutron Research Facility; Outline of Neutron Scattering Formalism; Small Angle Neutron Scattering at the National Institute of Standards and Technology; Neutron Reflectivity and Grazing Angle Diffraction; The Triple Axis and SPINS Spectrometers; Neutron Time-of-Flight Spectroscopy; Ultra-High Resolution Inelastic Neutron Scattering; Neutron Depth Profiling: Overview and Description of NIST Facilities; Prompt-Gamma Activation Analysis; Facilities for Fundamental Neutron Physics Research at the NIST Cold Neutron Research Facility

  4. The Center for Astronomy Education (CAE) and Our NSF Funded CCLI Phase III Collaboration of Astronomy Teaching Scholars (CATS) Program: Updates to Our New Community-Based Model for Astronomy Education Research

    Science.gov (United States)

    Brissenden, Gina; Impey, C.; Prather, E. E.; Lee, K. M.; CATS

    2010-01-01

    The Center for Astronomy Education (CAE) has been devoted to improving teaching & learning in Astro 101 by creating research-validated curriculum & assessment instruments for use in Astro 101 & by providing Astro 101 instructors professional development opportunities to increase their pedagogical content knowledge & instructional skills at implementing these curricula & assessment materials. To create sustainability and further expand this work, CAE, in collaboration with other national leaders in astronomy education & research, developed the Collaboration of Astronomy Teaching Scholars (CATS) Program. The primary goals of CATS are to: 1) increase the number of Astro 101 instructors conducting fundamental research in astronomy education 2) increase the amount of research-validated curriculum & assessment instruments available for use in Astro 101 3) increase the number of people prepared to develop & conduct their own CAE Teaching Excellence Workshops In our second year we have concluded a national study assessing the contribution students’ personal characteristics make to student learning gains and the effectiveness of interactive learning strategies. We have results from our classroom research validation study on the use of the "ClassAction” electronic learning system. We have begun creation of an assessment instrument designed specifically for Astro 101 to evaluate the effectiveness of our instruction in improving students’ attitudes & beliefs about science, and which is being informed by several of our studies and community input. We have also begun field-testing of our Solar System Concept Inventory. Additionally research into students’ beliefs and reasoning difficulties on topics in Cosmology is underway. We acknowledge the NSF for funding under Award No. 0715517, a CCLI Phase III Grant for the Collaboration of Astronomy Teaching Scholars (CATS) Program.

  5. Researches on Nutritional Behaviour in Romanian Black and White Primiparous Cows. Interruptions Number and their Duration in the Ration Consumption Time

    Directory of Open Access Journals (Sweden)

    Silvia Erina

    2012-10-01

    Full Text Available The study was carried out on 9 Romanian Black and White primiparous cows. The aim of this study was todetermine some aspect of nutritional behaviour of the cows. During the experiments, the following behaviour aspectswere determined: interruption number and their duration in the feed consumption time. Results showed that theadministration order of forages had an influence on the interruptions number, which was 0.74 less for hay in fibroussucculentorder (O1. For silage, the interruption number was 0.42 higher in fibrous-succulent order (O1. Betweenportion 1 (P1 and portion 3 (P3, the significant difference (p<0.05 was for interruptions duration, duringconsumption silage, in favour portion P1. Distinct significant differences (p<0.01 was observed for the interruptionnumber during consumption silage (0.95 sec. higher in P1 than in P3, for interruption duration (5.96 sec. higher inP1 than in P3. Between P2 and P3, significant difference (p<0.05 was observed for interruptions number duringconsumption silage and for average interruptions duration during consumption beet in favour to portion P2.Regarding the number of feedings per portion, always the differences were higher in the second feeding F1 than inthe first feeding F2.

  6. Preconditioner Updates Applied to CFD Model Problems

    Czech Academy of Sciences Publication Activity Database

    Birken, P.; Duintjer Tebbens, Jurjen; Meister, A.; Tůma, Miroslav

    2008-01-01

    Roč. 58, č. 11 (2008), s. 1628-1641 ISSN 0168-9274 R&D Projects: GA AV ČR 1ET400300415; GA AV ČR KJB100300703 Institutional research plan: CEZ:AV0Z10300504 Keywords : finite volume methods * update preconditioning * Krylov subspace methods * Euler equations * conservation laws Subject RIV: BA - General Mathematics Impact factor: 0.952, year: 2008

  7. Research Areas: Liver Disease

    Science.gov (United States)

    ... to their families, health professionals, and the public. Research Updates and News NIH study sheds light on ... findings to health professionals and the public. Support Research NIDDK invests in basic, clinical and translational research ...

  8. Effect of asynchronous updating on the stability of cellular automata

    International Nuclear Information System (INIS)

    Baetens, J.M.; Van der Weeën, P.; De Baets, B.

    2012-01-01

    Highlights: ► An upper bound on the Lyapunov exponent of asynchronously updated CA is established. ► The employed update method has repercussions on the stability of CAs. ► A decision on the employed update method should be taken with care. ► Substantial discrepancies arise between synchronously and asynchronously updated CA. ► Discrepancies between different asynchronous update schemes are less pronounced. - Abstract: Although cellular automata (CAs) were conceptualized as utter discrete mathematical models in which the states of all their spatial entities are updated simultaneously at every consecutive time step, i.e. synchronously, various CA-based models that rely on so-called asynchronous update methods have been constructed in order to overcome the limitations that are tied up with the classical way of evolving CAs. So far, only a few researchers have addressed the consequences of this way of updating on the evolved spatio-temporal patterns, and the reachable stationary states. In this paper, we exploit Lyapunov exponents to determine to what extent the stability of the rules within a family of totalistic CAs is affected by the underlying update method. For that purpose, we derive an upper bound on the maximum Lyapunov exponent of asynchronously iterated CAs, and show its validity, after which we present a comparative study between the Lyapunov exponents obtained for five different update methods, namely one synchronous method and four well-established asynchronous methods. It is found that the stability of CAs is seriously affected if one of the latter methods is employed, whereas the discrepancies arising between the different asynchronous methods are far less pronounced and, finally, we discuss the repercussions of our findings on the development of CA-based models.

  9. Conversion of Indigenous Agricultural Waste Feedstocks to Fuel Ethanol. Cooperative Research and Development Final Report, CRADA Number CRD-13-504

    Energy Technology Data Exchange (ETDEWEB)

    Elander, Richard [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-03-27

    This Cooperative Research and Development Agreement (CRADA) is between the National Renewable Energy Laboratory (NREL), a world leader in biomass conversion research and Ecopetrol American Inc., Ecopetrol S.A.'s U.S. subsidiary. The research and development efforts described in the Joint Work Statement (JWS) will take advantage of the strengths of both parties. NREL will use its Integrated Biorefinery Facility and vast experience in the conversion of lignocellulosic feedstocks to fuel ethanol to develop processes for the conversion of Ecopetrol's feedstocks. Ecopetrol will establish the infrastructure in Columbia to commercialize the conversion process.

  10. 2016 Gainesville Number Theory Conference

    CERN Document Server

    Garvan, Frank

    2017-01-01

    Gathered from the 2016 Gainesville Number Theory Conference honoring Krishna Alladi on his 60th birthday, these proceedings present recent research in number theory. Extensive and detailed, this volume features 40 articles by leading researchers on topics in analytic number theory, probabilistic number theory, irrationality and transcendence, Diophantine analysis, partitions, basic hypergeometric series, and modular forms. Readers will also find detailed discussions of several aspects of the path-breaking work of Srinivasa Ramanujan and its influence on current research. Many of the papers were motivated by Alladi's own research on partitions and q-series as well as his earlier work in number theory.  Alladi is well known for his contributions in number theory and mathematics. His research interests include combinatorics, discrete mathematics, sieve methods, probabilistic and analytic number theory, Diophantine approximations, partitions and q-series identities. Graduate students and researchers will find th...

  11. Valuing and Managing Diversity in Business and Industry: Literature Review and Models. Training and Development Research Center Project Number Fifty-Nine.

    Science.gov (United States)

    Johnson, Sandra J.

    An increasingly diverse work force is a definite trend in the United States, and a number of companies have linked valuing and managing diversity to increased productivity. Equal employment opportunity and affirmative action are pointed to as foundational to the development of formal programs for valuing or managing diversity in the workplace. The…

  12. Parents' Judgments of the Acceptability and Importance of Socially Interactive Robots for Intervening with Young Children with Disabilities. Social Robots Research Reports, Number 1

    Science.gov (United States)

    Dunst, Carl J.; Trivette, Carol M.; Prior, Jeremy; Hamby, Deborah W.; Embler, Davon

    2013-01-01

    A number of different types of socially interactive robots are being used as part of interventions with young children with disabilities to promote their joint attention and language skills. Parents' judgments of two dimensions (acceptance and importance) of the social validity of four different social robots were the focus of the study described…

  13. Mathematics Performance and Cognition (MPAC) Interview: Measuring First- and Second-Grade Student Achievement in Number, Operations, and Equality in Spring 2015. Research Report No. 2016-02

    Science.gov (United States)

    Schoen, Robert C.; LaVenia, Mark; Champagne, Zachary M.; Farina, Kristy; Tazaz, Amanda M.

    2017-01-01

    The following report describes an assessment instrument called the Mathematics Performance and Cognition (MPAC) interview. The MPAC interview was designed to measure two outcomes of interest. It was designed to measure first and second graders' mathematics achievement in number, operations, and equality, and it was also designed to gather…

  14. Research

    African Journals Online (AJOL)

    abp

    2017-11-30

    Nov 30, 2017 ... lowest number was in 2015. The number of vaccinated dogs has declined since 2012. Veterinary officers claimed that several attempts to organize mass vaccination campaigns often received low patronage as it is not mandatory for animal owners to have them vaccinated (Figure 3). Of the 9 health facilities ...

  15. Research

    African Journals Online (AJOL)

    abp

    2015-12-11

    Dec 11, 2015 ... table of random numbers, for each 2 participants, a number was randomly selected to choose the appropriate sequence. The random allocated sequence was generated by the principal investigator; the enrollment and assignation of participants were done by the investigation team (principal investigator ...

  16. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-11-18

    Nov 18, 2015 ... randomized into three treatment arms using random numbers obtained from random number table to be treated with a single dose (400mg) of different brands (Albenz-400 (India, Manufactured by Sterling Lab), Ovis (South Korea, Manufactured by DAE HWA. PHARM.CO.,LTD) and Wormin A 200 (Ethiopia, ...

  17. Intuitive numbers guide decisions

    Directory of Open Access Journals (Sweden)

    Ellen Peters

    2008-12-01

    Full Text Available Measuring reaction times to number comparisons is thought to reveal a processing stage in elementary numerical cognition linked to internal, imprecise representations of number magnitudes. These intuitive representations of the mental number line have been demonstrated across species and human development but have been little explored in decision making. This paper develops and tests hypotheses about the influence of such evolutionarily ancient, intuitive numbers on human decisions. We demonstrate that individuals with more precise mental-number-line representations are higher in numeracy (number skills consistent with previous research with children. Individuals with more precise representations (compared to those with less precise representations also were more likely to choose larger, later amounts over smaller, immediate amounts, particularly with a larger proportional difference between the two monetary outcomes. In addition, they were more likely to choose an option with a larger proportional but smaller absolute difference compared to those with less precise representations. These results are consistent with intuitive number representations underlying: a perceived differences between numbers, b the extent to which proportional differences are weighed in decisions, and, ultimately, c the valuation of decision options. Human decision processes involving numbers important to health and financial matters may be rooted in elementary, biological processes shared with other species.

  18. Non-Parametric Bayesian Updating within the Assessment of Reliability for Offshore Wind Turbine Support Structures

    DEFF Research Database (Denmark)

    Ramirez, José Rangel; Sørensen, John Dalsgaard

    2011-01-01

    This work illustrates the updating and incorporation of information in the assessment of fatigue reliability for offshore wind turbine. The new information, coming from external and condition monitoring can be used to direct updating of the stochastic variables through a non-parametric Bayesian...... updating approach and be integrated in the reliability analysis by a third-order polynomial chaos expansion approximation. Although Classical Bayesian updating approaches are often used because of its parametric formulation, non-parametric approaches are better alternatives for multi-parametric updating...... with a non-conjugating formulation. The results in this paper show the influence on the time dependent updated reliability when non-parametric and classical Bayesian approaches are used. Further, the influence on the reliability of the number of updated parameters is illustrated....

  19. Research

    African Journals Online (AJOL)

    abp

    2015-09-09

    Sep 9, 2015 ... Orthopaedics and Traumatology, Faculty of Medicine, Adiyaman University, 02040 Adiyaman, Turkey,3Department of Orthopedics and. Traumatology, Umraniye Research and Education Hospital, 34899 Istanbul, Turkey, 4Department of Orthopedics and Traumatology, Umraniye. Research and Education ...

  20. Research

    African Journals Online (AJOL)

    The research methodology module was reviewed as part of the overall revision of the undergraduate physiotherapy curriculum of ... Structuring the research methodology module using an EBP teaching framework prepares students to formulate a research question, effectively ... manage, and organise bibliographic citations.

  1. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-05-13

    May 13, 2015 ... Systems (SEEDS)-INDEPTH Network Accra, Ghana, 3KEMRI/Wellcome Trust Research Programme, The Centre of Geographical Medicine Research-. Coast, Kilifi, Kenya, 4Population Health Sciences/Research Support Unit, Faculty of Health Sciences, Aga Khan University- East Africa, Nairobi,. Kenya ...

  2. Research

    African Journals Online (AJOL)

    research process, as part of which students must find and appraise evidence from research.[5] This highlights that teaching research methodology is inclined towards equipping students ... Students believed that evidence-based practice was vital, yet their understanding of the concept was restricted when compared with the.

  3. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-03-02

    Mar 2, 2015 ... this program provided short-term and long-term research training to. US infectious disease fellows who would work on collaborative research projects with Kenyan trainees. Since the program began in. 1988, there have been 56 US trainees, and 13 of these continue to collaborate with Kenyan researchers.

  4. Geothermal Greenhouse Development Update

    Energy Technology Data Exchange (ETDEWEB)

    Lienau, Paul J.

    1997-01-01

    Greenhouse heating is one of the popular applications of low-to moderated-temperature geothermal resources. Using geothermal energy is both an economical and efficient way to heat greenhouses. Greenhouse heating systems can be designed to utilize low-temperature (>50oC or 122oF) resources, which makes the greenhouse an attractive application. These resources are widespread throughout the western states providing a significant potential for expansion of the geothermal greenhouse industry. This article summarizes the development of geothermal heated greenhouses, which mainly began about the mid-1970's. Based on a survey (Lienau, 1988) conducted in 1988 and updated in 1997, there are 37 operators of commercial greenhouses. Table 1 is a listing of known commercial geothermal greenhouses, we estimate that there may be an additional 25% on which data is not available.

  5. [Update Chagas disease].

    Science.gov (United States)

    Molina, Israel; Salvador, Fernando; Sánchez-Montalvá, Adrián

    2016-02-01

    The constant migration flows have favored the presence of people with Chagas disease in regions traditionally regarded as non-endemic, such as North America, Europe, Asia and Oceania. This has forced both health authorities and professionals to be updated in order to respond to such a demand for assistance. Recent years have led to significant progress in the field of diagnosis and treatment of Chagas disease, one of the most neglected tropical diseases. Recent clinical trials are providing new evidence that makes the management of these patients, a constant challenge for the professionals involved. Innovative diagnostic tools and therapeutic regimens, allow us to face the future of Chagas disease with optimism. Copyright © 2016 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  6. Y2K UPDATE

    CERN Multimedia

    Sverre JARP

    1999-01-01

    Concerning Y2K preparation, please note the following:Everybody, who has a NICE installation on his/her PC, needs to log in to NICE at least once before Xmas to get the Y2K update installed. This applies especially to dual boot systems.The test schedule on Y2Kplus.cern.ch will be prolonged. The last restart took place on 10 November and two more will take place on 24 November and 8 December, respectively. The Oracle users responsible for the maintenance of Oracle Forms applications which include PL/SQL blocks where date fields are handled with the default format are requested to contact oracle.support@cern.ch at their earliest convenience.Sverre Jarp (CERN Y2K co-ordinator, phone: 74944)

  7. Amblyopia update: new treatments.

    Science.gov (United States)

    Vagge, Aldo; Nelson, Leonard B

    2016-09-01

    This review article is an update on the current treatments for amblyopia. In particular, the authors focus on the concepts of brain plasticity and their implications for novel treatment strategies for both children and adults affected by amblyopia. A variety of strategies has been developed to treat amblyopia in children and adults. New evidence on the pathogenesis of amblyopia has been obtained both in animal models and in clinical trials. Mainly, these studies have challenged the classical concept that amblyopia becomes untreatable after the 'end' of the sensitive or critical period of visual development, because of a lack of sufficient plasticity in the adult brain. New treatments for amblyopia in children and adults are desirable and should be encouraged. However, further studies should be completed before such therapies are widely accepted into clinical practice.

  8. Update on equine allergies.

    Science.gov (United States)

    Fadok, Valerie A

    2013-12-01

    Horses develop many skin and respiratory disorders that have been attributed to allergy. These disorders include pruritic skin diseases, recurrent urticaria, allergic rhinoconjunctivitis, and reactive airway disease. Allergen-specific IgE has been detected in these horses, and allergen-specific immunotherapy is used to ameliorate clinical signs. The best understood atopic disease in horses is insect hypersensitivity, but the goal of effective treatment with allergen-specific immunotherapy remains elusive. In this review, updates in pathogenesis of allergic states and a brief mention of the new data on what is known in humans and dogs and how that relates to equine allergic disorders are discussed. Copyright © 2013 Elsevier Inc. All rights reserved.

  9. AOS clearwater project update

    Energy Technology Data Exchange (ETDEWEB)

    Palmgren, Claes [Alberta Oilsands Inc (Canada)

    2011-07-01

    The Athabasca oil sands, located in northeastern Alberta, are one of the largest deposits of bitumen in the world. In this presentation Alberta Oilsands Inc. provides an update of their two phase Clearwater project which aims at using an SLP-SAGD system to recover Athabasca bitumen. The Clearwater project site is located nearby the Fort McMurray regional airport. The idea behind the project is to utilize a low pressure SAGD system in combination with a co-injected solvent in order to extract the bitumen. The injected solvent mixes with the bitumen, decreasing its viscosity and improving its ability to flow. This type of system requires only 1000 kPa of operating pressure which leads to a lower steam to oil ratio. By the end of phase one, the Clearwater project aims at bringing in 4,500 barrels of oil per day (BOPD) and 15,000 to 25,000 BOPD by the end of phase two.

  10. 75 FR 21979 - NRC Region II Address and Main Telephone Number Changes

    Science.gov (United States)

    2010-04-27

    ... Region II Address and Main Telephone Number Changes AGENCY: Nuclear Regulatory Commission. ACTION: Final... address for its Region II office and to update the main telephone number. The Region II office move and... update the NRC Region II office street address and office main telephone number. The physical location of...

  11. Update on an Interstellar Asteroid

    Science.gov (United States)

    Kohler, Susanna

    2018-01-01

    Whats the news coming from the research world on the interstellar asteroid visitor, asteroid 1I/Oumuamua? Read on for an update from a few of the latest studies.What is Oumuamua?In lateOctober2017, the discovery of minor planet 1I/Oumuamua was announced. This body which researchers first labeled asa comet and later revised to an asteroid had just zipped around the Sun and was already in the process of speeding away whenwe trained our telescopes on it. Its trajectory, however, marked it as being a visitor from outside our solar system: the first knownvisitorof its kind.Since Oumuamuasdiscovery, scientists have been gathering as many observations of this bodyas possible before it vanishes into the distance. Simultaneously, theorists have leapt at the opportunity to explain its presence and the implications its passage has on our understanding of our surroundings. Here we present just a few of the latest studies that have been published on this first detected interstellar asteroid including several timelystudies published in our new journal, Research Notes of the AAS.The galactic velocity of Oumuamua does not coincide with any of the nearest stars to us. [Mamajek 2018]Where Did Oumuamua Come From?Are we sure Oumuamua didnt originate in our solar system andget scattered into a weird orbit? Jason Wright (The Pennsylvania State University) demonstrates via a series of calculations that no known solar system body could have scattered Oumuamua onto its current orbit nor could any stillunknown object bound to our solar system.Eric Mamajek (Caltech and University of Rochester) showsthat thekinematics of Oumuamua areconsistent with what we might expect of interstellar field objects, though he argues that its kinematics suggest its unlikely to have originated from many of the neareststellar systems.What AreOumuamuas Properties?Oumuamuas light curve. [Bannister et al. 2017]A team of University of Maryland scientists led by Matthew Knight captured a light curve of Oumuamua using

  12. Experiences and wisdom behind the numbers: qualitative analysis of the National Action Alliance for Suicide Prevention's Research Prioritization Task Force stakeholder survey.

    Science.gov (United States)

    Booth, Chelsea L

    2014-09-01

    The Research Prioritization Task Force of the National Action Alliance for Suicide Prevention conducted a stakeholder survey including 716 respondents from 49 U.S. states and 18 foreign countries. To conduct a qualitative analysis on responses from individuals representing four main stakeholder groups: attempt and loss survivors, researchers, providers, and policy/administrators. This article focuses on a qualitative analysis of the early-round, open-ended responses collected in a modified online Delphi process, and, as an illustration of the research method, focuses on analysis of respondents' views of the role of life and emotional skills in suicide prevention. Content analysis was performed using both inductive and deductive code and category development and systematic qualitative methods. After the inductive coding was completed, the same data set was re-coded using the 12 Aspirational Goals (AGs) identified by the Delphi process. Codes and thematic categories produced from the inductive coding process were, in some cases, very similar or identical to the 12 AGs (i.e., those dealing with risk and protective factors, provider training, preventing reattempts, and stigma). Other codes highlighted areas that were not identified as important in the Delphi process (e.g., cultural/social factors of suicide, substance use). Qualitative and mixed-methods research are essential to the future of suicide prevention work. By design, qualitative research is explorative and appropriate for complex, culturally embedded social issues such as suicide. Such research can be used to generate hypotheses for testing and, as in this analysis, illuminate areas that would be missed in an approach that imposed predetermined categories on data. Published by Elsevier Inc.

  13. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-09-01

    0.006) were significantly associated with obesity. Conclusion: .... average monthly salary, number of years of experience, physical activity levels, blood ..... V.Epidemiological and nutritional transition in Mexico: rapid increase of ...

  14. Extraglottic airway devices: technology update

    Directory of Open Access Journals (Sweden)

    Sharma B

    2017-08-01

    Full Text Available Bimla Sharma, Chand Sahai, Jayashree Sood Department of Anaesthesiology, Pain and Perioperative Medicine, Sir Ganga Ram Hospital, New Delhi, India Abstract: Extraglottic airway devices (EADs have revolutionized the field of airway management. The invention of the laryngeal mask airway was a game changer, and since then, there have been several innovations to improve the EADs in design, functionality, safety and construction material. These have ranged from changes in the shape of the mask, number of cuffs and material used, like rubber, polyvinylchloride and latex. Phthalates, which were added to the construction material in order to increase device flexibility, were later omitted when this chemical was found to have serious adverse reproductive outcomes. The various designs brought out by numerous companies manufacturing EADs resulted in the addition of several devices to the airway market. These airway devices were put to use, many of them with inadequate or no evidence base regarding their efficacy and safety. To reduce the possibility of compromising the safety of the patient, the Difficult Airway Society (DAS formed the Airway Device Evaluation Project Team (ADEPT to strengthen the evidence base for airway equipment and vet the new extraglottic devices. A preuse careful analysis of the design and structure may help in better understanding of the functionality of a particular device. In the meantime, the search for the ideal EAD continues. Keywords: extraglottic airway devices, laryngeal mask airway, other extraglottic airway devices, safety, technology update

  15. Updating of the bovine neosporosis

    Directory of Open Access Journals (Sweden)

    Alexander Martínez Contreras

    2012-06-01

    Full Text Available In the fields of Medicine and bovine production, there is a wide variety of diseases affecting reproduction, in relation to the number of live births, the interval between births and open days, among others. Some of these diseases produce abortions and embryonic death, which explain the alteration of reproductive parameters. Many of these diseases have an infectious origin, such as parasites, bacteria, viruses and fungi, which are transmitted among animals. Besides, some of them have zoonotic features that generate problems to human health. Among these agents, the Neospora caninum, protozoan stands out. Its life cycle is fulfilled in several species of animals like the dog and the coyote. These two act as its definitive hosts and the cattle as its intermediary host. The Neospora caninum causes in the infected animals, reproductive disorders, clinical manifestations and decreased production which affects productivity of small, medium and large producers. Because of this, diagnostic techniques that allow understanding the epidemiological behavior of this disease have been developed. However in spite of being a major agent in the bovine reproductive health, few studies have been undertaken to determine the prevalence of this agent around the world. Therefore, the objective of this review was to collect updated information on the behavior of this parasite, targeting its epidemiology, its symptoms, its impact on production and the methods of its control and prevention.

  16. Facilities for Study and Research in the Offices of the United States Government at Washington. Bulletin, 1909, No. 1. Whole Number 398

    Science.gov (United States)

    Hadley, Arthur Twining

    1909-01-01

    This bulletin contains a report prepared by President Hadley of Yale University on the facilities for advanced study and research in the offices of the National Government at Washington. Especial interest attaches to this publication. It sets forth, in compact form, information which has frequently been sought by institutions and individuals…

  17. Revitalization of Japanese Business and Industry: Implications for Training and Organization Development. Training and Development Research Center Project Number Twenty-Eight.

    Science.gov (United States)

    Lindberg, Karen J.

    A research study, based on a survey of the literature, sought to: (1) analyze recent economic, technological, and sociological trends in Japan; (2) analyze how those trends have or have not had an impact on Japan's historical and currently famous approach to the management of its human resources; and (3) based on findings, present arguments for or…

  18. Effects of a Socially Interactive Robot on the Conversational Turns between Parents and Their Young Children with Autism. Social Robots Research Reports, Number 6

    Science.gov (United States)

    Dunst, Carl J.; Hamby, Deborah W.; Trivette, Carol M.; Prior, Jeremy; Derryberry, Graham

    2013-01-01

    The effects of a socially interactive robot on the conversational turns between four young children with autism and their mothers were investigated as part of the intervention study described in this research report. The interventions with each child were conducted over 4 or 5 days in the children's homes where a practitioner facilitated…

  19. Infrastructure, Components and System Level Testing and Analysis of Electric Vehicles: Cooperative Research and Development Final Report, CRADA Number CRD-09-353

    Energy Technology Data Exchange (ETDEWEB)

    Neubauer, J.

    2013-05-01

    Battery technology is critical for the development of innovative electric vehicle networks, which can enhance transportation sustainability and reduce dependence on petroleum. This cooperative research proposed by Better Place and NREL will focus on predicting the life-cycle economics of batteries, characterizing battery technologies under various operating and usage conditions, and designing optimal usage profiles for battery recharging and use.

  20. Key Findings and Recommendations from the Coös Youth Study: Research from the First Half of the Study. Regional Issue Brief Number 41

    Science.gov (United States)

    Staunton, Michael S.; Jaffee, Eleanor M.

    2014-01-01

    In this brief, authors Michael Staunton and Eleanor Jaffee review the key findings and recommendations from research conducted in the first half of the Coös Youth Study, which began in 2008 and is planned to continue through 2018. The study explores young people's decisions about their educational and job opportunities in rural northern New…

  1. The National Shipbuilding Research Program 1985 Ship Production Symposium. Volume 1, Paper Number 20: Marine Industry Standards of the U.S. and the World

    Science.gov (United States)

    1985-09-01

    de Janeiro shipyard of EMAQ- Engenhario E Maquinas S.A.; research for tune chairman of the National Science Board’s Committee on Maritime...this expedite preparation of a Brazilian standard but it assured acceptance by the classification societies. -539- FIGURE 5 - ENGENHARIA E MAQUINAS S.A

  2. Academic Ambitions and Library Development: The American Bureau of Industrial Research and the State Historical Society of Wisconsin, 1904-18. Occasional Paper Number 159.

    Science.gov (United States)

    Colson, John Calvin

    Intended to contribute to a better understanding of research library development in the United States, this report describes the history of the development of the library of the State Historical Society of Wisconsin from 1904 to 1918. It is based on records of the relationships between three principals--John R. Commons and Richard T. Ely (members…

  3. Archives of Environmental Health, Volume 18 Number 4. Ninth AMA Air Pollution Medical Research Conference, Denver, July 22-24, 1968.

    Science.gov (United States)

    Barton, Frank

    Papers read before the Ninth American Medical Association (AMA) Air Pollution Medical Research Conference, Denver, Colorado, July 22-24, 1968, are presented in this document. Topics deal with the relationship and effects of atmospheric pollution to respiratory diseases, epidemiology, human physiological reactions, urban morbidity, health of school…

  4. Factoring Fermat Numbers

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 1. Factoring Fermat Numbers. C E Veni Madhavan. Research News Volume 1 Issue 1 January 1996 pp 108-108. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/001/01/0108-0108. Author Affiliations.

  5. Fermion Number Fractionization

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 13; Issue 8. Fermion Number Fractionization. Kumar Rao Narendra Sahu Prasanta K ... Author Affiliations. Kumar Rao1 Narendra Sahu1 Prasanta K Panigrahi1. Theoretical Physics Division, Physical Research Laboratory, Ahmedabad 380 009, India ...

  6. Factoring Fermat Numbers

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 1. Factoring Fermat Numbers. C E Veni Madhavan. Research News Volume 1 Issue 1 January 1996 pp 108-108. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/001/01/0108-0108 ...

  7. An update survey of academic radiologists' clinical productivity.

    Science.gov (United States)

    Lu, Ying; Zhao, Shoujun; Chu, Philip W; Arenson, Ronald L

    2008-07-01

    The total number of procedures and their relative value units (RVUs) were used to measure the productivity of radiologists. Besides variations in productivity due to differences in the percentage of clinical effort, baseline productivity also varies among clinical subspecialty sections. The authors' previous research used the full-time equivalent (FTE) as the unit to adjust for differences in the percentage of clinical effort and a set of adjustment factors (or calibration constants) to modify the default work RVUs according to types of procedures. These adjustments led to comparable average productivity measurements across subspecialty sections. Since 2003, radiology practice has continued to change, including the introduction of positron emission tomography/computed tomography into clinical practice, suggesting a need to update the understanding of clinical productivity and refine the authors' adjustment procedure. In this study, the authors analyzed the most recent survey of academic departments and derived updated adjustment factors for differences in workload among subspecialty sections. The results can be used to determine faculty staffing requirements and evaluate radiologists' performance. A survey performed by the Society of Chairmen of Academic Radiology Departments collected data in 2006 for 1,134 radiologists in 24 departments, including 10 departments that also reported productivity in an earlier 2003 survey. These data included the numbers of procedures (represented by Current Procedural Terminology [CPT] codes) performed by radiologists, percentage clinical effort, subspecialty sections, and the number of clinical days. The numbers of CPT codes were converted into total work RVUs per FTE faculty member. By grouping the CPT codes into 6 prespecified examination categories, adjustment factors were created to adjust the RVUs for CPT categories to ensure that the median total adjusted work RVUs from different subspecialty sections were comparable

  8. Update in clinical allergy and immunology.

    Science.gov (United States)

    von Gunten, S; Marsland, B J; von Garnier, C; Simon, D

    2012-12-01

    In the recent years, a tremendous body of studies has addressed a broad variety of distinct topics in clinical allergy and immunology. In this update, we discuss selected recent data that provide clinically and pathogenetically relevant insights or identify potential novel targets and strategies for therapy. The role of the microbiome in shaping allergic immune responses and molecular, as well as cellular mechanisms of disease, is discussed separately and in the context of atopic dermatitis, as an allergic model disease. Besides summarizing novel evidence, this update highlights current areas of uncertainties and debates that, as we hope, shall stimulate scientific discussions and research activities in the field. © 2012 John Wiley & Sons A/S.

  9. Update to the Fissile Materials Disposition program SST/SGT transportation estimation

    International Nuclear Information System (INIS)

    John Didlake

    1999-01-01

    This report is an update to ''Fissile Materials Disposition Program SST/SGT Transportation Estimation,'' SAND98-8244, June 1998. The Department of Energy Office of Fissile Materials Disposition requested this update as a basis for providing the public with an updated estimation of the number of transportation loads, load miles, and costs associated with the preferred alternative in the Surplus Plutonium Disposition Final Environmental Impact Statement (EIS)

  10. Thread-Level Parallel Indexing of Update Intensive Moving-Object Workloads

    DEFF Research Database (Denmark)

    Sidlauskas, Darius; Ross, Kenneth A.; Jensen, Christian Søndergaard

    2011-01-01

    Modern processors consist of multiple cores that each support parallel processing by multiple physical threads, and they offer ample main-memory storage. This paper studies the use of such processors for the processing of update-intensive moving-object workloads that contain very frequent updates...... linearly with the number of hardware threads, and that it significantly outperforms the previous state-of-the-art approach in terms of update throughput and query freshness....

  11. Update of CERN exchange network

    CERN Multimedia

    2003-01-01

    An update of the CERN exchange network will be done next April. Disturbances or even interruptions of telephony services may occur from 4th to 24th April during evenings from 18:30 to 00:00 but will not exceed more than 4 consecutive hours (see tentative planning below). CERN divisions are invited to avoid any change requests (set-ups, move or removals) of telephones and fax machines from 4th to 25th April. Everything will be done to minimize potential inconveniences which may occur during this update. There will be no loss of telephone functionalities. CERN GSM portable phones won't be affected by this change. Should you need more details, please send us your questions by email to Standard.Telephone@cern.ch. DateChange typeAffected areas April 11 Update of switch in LHC 4 LHC 4 Point April 14 Update of switch in LHC 5 LHC 5 Point April 15 Update of switches in LHC 3 and LHC 2 Points LHC 3 and LHC 2 April 22 Update of switch N4 Meyrin Ouest April 23 Update of switch  N6 Prévessin Site Ap...

  12. Drawing a random number

    DEFF Research Database (Denmark)

    Wanscher, Jørgen Bundgaard; Sørensen, Majken Vildrik

    2006-01-01

    Random numbers are used for a great variety of applications in almost any field of computer and economic sciences today. Examples ranges from stock market forecasting in economics, through stochastic traffic modelling in operations research to photon and ray tracing in graphics. The construction...... of a model or a solution method requires certain characteristics of the random numbers used. This is usually a distribution classification, which the sequence of random numbers must fulfill; of these some are very hard to fulfill and others are next to impossible. Today mathematics allows us to transform...... highly uniform multidimensional draws, which are highly relevant for todays traffic models. This paper shows among others combined shuffling and scrambling seems needless, that scrambling gives the lowest correlation and that there are detectable differences between random numbers, dependent...

  13. Research

    African Journals Online (AJOL)

    abp

    2015-01-19

    Jan 19, 2015 ... in Cameroon. This study aimed at examining the sexual risk behaviours of high school female learners in Mbonge subdivision of rural Cameroon. ... Despite a wealth of research on youth, little research has been done on the sexual ..... Behavior, and Mental Health: a study of University Students in. Uganda.

  14. researchers

    African Journals Online (AJOL)

    African Sociological Review, 7, (2), 2003, pp.149-161. RESEARCH REPORTS. Revisiting “insiders' and 'outsiders' as social researchers. Marlize Rabe .... use of knowledgeable fieldworkers is then examined by focussing on the work ... A study by Russell (1995:p.95–97) on the long-term effects of incestuous abuse.

  15. Research

    African Journals Online (AJOL)

    2014-05-06

    May 6, 2014 ... facilitate and support articulation between the ECT mid-level worker qualification and the professional B EMC degree. Methods. The researchers used an exploratory, sequential mixed-method design, which is characterised by a qualitative phase of research followed by a quantitative phase. This design is ...

  16. Research

    African Journals Online (AJOL)

    In-depth telephonic interviews were voice recorded and transcribed. Through an inductive ... Two research assistants conducted the research to ..... Assistant Nutritionist. 1.25. M. 30.5. Single. BSc Food Science and Technology. Dietitian. 6. M. 25.6. Single. BSc Human Nutrition and Dietetics. Dietitian. 1. M. 29.6. Single.

  17. NASA/DOD Aerospace Knowledge Diffusion Research Project. Report number 21: US aerospace industry librarians and technical information specialists as information intermediaries: Results of the phase 2 survey

    Science.gov (United States)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.

    1994-01-01

    The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DoD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis U.S. aerospace industry librarians and technical information specialists as information intermediaries.

  18. An industry update: the latest developments in therapeutic delivery.

    Science.gov (United States)

    Steinbach, Oliver C

    2018-02-01

    The present industry update covers the period 1 October-31 October 2017, with information sourced from company press releases, regulatory and patent agencies as well as scientific literature. While the corporate news in October was traditionally dominated by the announcement of the third quarter results, with most of them showing market and revenue growth but also an increasing number of initial public offerings after years of slower financial development, we also saw trends continuing toward an increasing number of convergences of drugs with nanotechnology, devices and 21st century information technology. Whether it is using E Ink's 'Smart Patch', AstraZeneca's autoinjector, Elektrofi's Elektroject suspensions or NanOlogy's NanoPac, there is an ever increasing number of combinations dof devices, drugs and applications reaching, more and more the clinic and the market. Controlled release is another feature increasingly addressed by many of the above innovations. For example, the drug-loaded x-ray imageable microscopic beads that have been developed by researchers at UCL Cancer Institute (London, UK) take this one step further in order to pursue local, controlled and in situ validated local delivery.

  19. About the necessity to update the Radiological safety and protection regulations of the National Institute of Nuclear Research (ININ); Sobre la necesidad de actualizar el reglamento de proteccion y seguridad radiologica del ININ

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez R, J.T. [Instituto Nacional de Investigaciones Nucleares, Salazar (Mexico). Dept. de Metrologia

    1997-07-01

    It is argued the necessity to update the Radiological safety and Protection regulations (Review 3) of ININ, with the purpose that it implements the ICRU operative magnitudes system. Such a system used with radiological protection purposes. The objective of this system is to do an estimation of the effective equivalent dose H{sub E} and/or the Effective dose E, proposed in the ICRP 26 and ICRU 60 dose limits systems respectively. (Author)

  20. Updating the Psoriatic Arthritis (PsA) Core Domain Set

    DEFF Research Database (Denmark)

    Orbai, Ana-Maria; de Wit, Maarten; Mease, Philip J

    2017-01-01

    OBJECTIVE: To include the patient perspective in accordance with the Outcome Measures in Rheumatology (OMERACT) Filter 2.0 in the updated Psoriatic Arthritis (PsA) Core Domain Set for randomized controlled trials (RCT) and longitudinal observational studies (LOS). METHODS: At OMERACT 2016, research...... conducted to update the PsA Core Domain Set was presented and discussed in breakout groups. The updated PsA Core Domain Set was voted on and endorsed by OMERACT participants. RESULTS: We conducted a systematic literature review of domains measured in PsA RCT and LOS, and identified 24 domains. We conducted...... and breakout groups at OMERACT 2016 in which findings were presented and discussed. The updated PsA Core Domain Set endorsed with 90% agreement by OMERACT 2016 participants included musculoskeletal disease activity, skin disease activity, fatigue, pain, patient's global assessment, physical function, health...

  1. Multiplicative updates for the LASSO

    DEFF Research Database (Denmark)

    Mørup, Morten; Clemmensen, Line Katrine Harder

    2007-01-01

    .e. least squares minimization with $L_1$-norm regularization, since the multiplicative updates (MU) can efficiently exploit the structure of the problem traditionally solved using quadratic programming (QP). We derive an algorithm based on MU for the LASSO and compare the performance to Matlabs standard QP......Multiplicative updates have proven useful for non-negativity constrained optimization. Presently, we demonstrate how multiplicative updates also can be used for unconstrained optimization. This is for instance useful when estimating the least absolute shrinkage and selection operator (LASSO), i...

  2. Updating optical pseudoinverse associative memories.

    Science.gov (United States)

    Telfer, B; Casasent, D

    1989-07-01

    Selected algorithms for adding to and deleting from optical pseudoinverse associative memories are presented and compared. New realizations of pseudoinverse updating methods using vector inner product matrix bordering and reduced-dimensionality Karhunen-Loeve approximations (which have been used for updating optical filters) are described in the context of associative memories. Greville's theorem is reviewed and compared with the Widrow-Hoff algorithm. Kohonen's gradient projection method is expressed in a different form suitable for optical implementation. The data matrix memory is also discussed for comparison purposes. Memory size, speed and ease of updating, and key vector requirements are the comparison criteria used.

  3. A Supply and Demand Update of the Molybdenum-99 Market

    International Nuclear Information System (INIS)

    2012-08-01

    Medical diagnostic imaging techniques using technetium-99m account for roughly 80% of all nuclear medicine procedures, representing over 30 million examinations worldwide every year. Disruptions in the supply chain of these medical isotopes - which have half-lives of 66 hours for molybdenum-99 ( 99 Mo) and 6 hours for its daughter isotope, technetium-99m (' 99m Tc), and thus must be produced continually - can lead to cancellations or delays in important medical testing services. Unfortunately, supply reliability has declined over the past decade due to unexpected or extended shutdowns at the few ageing 99 Mo-producing research reactor and processing facilities. These shutdowns have created global supply shortages. In 2011, the OECD Nuclear Energy Agency (NEA), along with its High-level Group on the Security of Supply of Medical Radioisotopes (HLG-MR), released a report that presents the reasons behind the lack of infrastructure that led to global supply shortages and a policy approach to encourage long-term medical isotope supply security. In that report, The Supply of Medical Radioisotopes: The Path to Reliability, the NEA also provides potential futures of supply and demand out to 2030. Since the release of The Path there have been a number of changes in the market and therefore this document provides an update on the 2011 supply and demand situation. This update is based on information provided to the NEA by members of the HLG-MR and other key stakeholders. This presentation of supply and demand future scenarios for the 99 Mo market revises previous NEA future scenarios based on new data and target conversion commitments from the supply chain. The update, unfortunately, does not present a more optimistic future scenario than previous presentations - the concern around the uneconomic situation of the supply chain continues to dominate the potential for new projects. This results in the potential for long-term shortages within the decade. However, there are a

  4. Optical Materials, Adhesive and Encapsulant, III-V, and Optical Characterization Evaluation: Cooperative Research and Development Final Report, CRADA Number CRD-07-216

    Energy Technology Data Exchange (ETDEWEB)

    Kempe, M.

    2012-11-01

    SolFocus is currently developing solar technology for utility scale application using Winston collector based concentrating photovoltaics (CPV). Part of that technology development includes small mirror dishes and front surface reflectors, and bonding the separate parts to the assembly. Mirror panels must meet rigid optical specifications in terms of radius of curvature, slope errors and specularity. The reflective surfaces must demonstrate long term durability and maintain high reflectivity. Some bonded surfaces must maintain adhesion and transparency under high concentrations and high temperatures. Others will experience moderate temperatures and do not require transparency. NREL researchers have developed methods and tools that address these related areas.

  5. Research

    African Journals Online (AJOL)

    abp

    2015-07-14

    Jul 14, 2015 ... All incoming sputum smears were stained for. ZN examination under routine conditions. Slides were read using the available conventional bright-field microscope (1000x). After reading, all slides were kept in slide boxes, which were labeled to specify the study phase, study site, box number, and slide ID.

  6. Research

    African Journals Online (AJOL)

    ebutamanya

    2016-04-22

    Apr 22, 2016 ... The other common specific skin lesions were lichen planus/lichenoid dermatitis 27(12.9% of 209 cases), verruca vulgaris 25 (12% of 209 cases). Conclusion: The number of histologically diagnosed non-neoplastic skin lesions is relatively small. There is a very wide spectrum of non-neoplastic skin lesions ...

  7. Research

    African Journals Online (AJOL)

    abp

    2013-05-13

    value ≤ 0.05) with male gender, region of origin, number of life time sexual partners and serum albumin below 3.5 mg/dl after univariate and multivariate analysis. Conclusion: Alcohol misuse and alcoholic liver disease is ...

  8. Research

    African Journals Online (AJOL)

    2014-05-24

    May 24, 2014 ... conducting semi-structured interviews to elicit student perspectives,[8] a survey design to reach larger numbers of interns .... scholarship with regard to teaching, learning and assessment. This has resulted in changes to ..... 32. Record clinical data systematically. 33. Be sensitive to the needs of nursing staff.

  9. Research

    African Journals Online (AJOL)

    abp

    2017-11-03

    Nov 3, 2017 ... Furosemide, lisinopril and amlodipine were the most frequently prescribed drugs and had the greatest likelihood for nephrotoxicity. The number of medications and hypertension (as co-morbidity) were significant and independent predictors of DDIs among the patients. About 70% of the drug combinations ...

  10. Research

    African Journals Online (AJOL)

    cqq1a

    2010-08-29

    Aug 29, 2010 ... Page number not for citation purposes. 1. Pattern of ... characterize the spectrum of the effects of SLE with regards to disease activity and its impact on the quality of life (QoL), a case control study ... Conclusion: Physicians should focus on QoL and how to improve it; health education regarding the negative.

  11. Research

    African Journals Online (AJOL)

    personal motivation influence what they learn, as well as how they apply and continuously practise acquired knowledge and skills. ... The number in brackets next to the quotes given below refers to the respondent and 'T' indicates that the quote was translated from the original. Afrikaans. Demographic profile of interviewees.

  12. Research

    African Journals Online (AJOL)

    abp

    2017-09-21

    Sep 21, 2017 ... of optic nerve insult [11,12]. On the contrary, a transient intraocular pressure elevation role in causing optic neuropathy is doubtful. We excluded patients with vulnerable discs from our study such as glaucoma and previous ipsilateral ischemic optic neuropathy (Table. 1). A total number of 28 patients were ...

  13. ADVISORY ON UPDATED METHODOLOGY FOR ...

    Science.gov (United States)

    The National Academy of Sciences (NAS) published the Biological Effects of Ionizing Radiation (BEIR) committee's report (BEIR VII) on risks from ionizing radiation exposures in 2006. The Committee analyzed the most recent epidemiology from the important exposed cohorts and factored in changes resulting from the updated analysis of dosimetry for the Japanese atomic bomb survivors. To the extent practical, the Committee also considered relevant radiobiological data, including that from the Department of Energy's low dose effects research program. Based on the review of this information, the Committee proposed a set of models for estimating risks from low-dose ionizing radiation. ORIA then prepared a white paper revising the Agency's methodology for estimating cancer risks from exposure to ionizing radiation in light of this report and other relevant information. This is the first product to be developed as a result of the BEIR VII report. We requested that the SAB conduct an advisory during the development of this methodology. The second product to be prepared will be a revised version of the document,

  14. Tetraplegia Management Update.

    Science.gov (United States)

    Fridén, Jan; Gohritz, Andreas

    2015-12-01

    Tetraplegia is a profound impairment of mobility manifesting as a paralysis of all 4 extremities owing to cervical spinal cord injury. The purpose of this article is to provide an update and analyze current management, treatment options, and outcomes of surgical reconstruction of arm and hand function. Surgical restoration of elbow and wrist extension or handgrip has tremendous potential to improve autonomy, mobility, and critical abilities, for example, eating, personal care, and self-catheterization and productive work in at least 70% of tetraplegic patients. Tendon and nerve transfers, tenodeses, and joint stabilizations reliably enable improved arm and hand usability, reduce muscle imbalance and pain in spasticity, and prevent joint contractures. One-stage combined procedures have proven considerable advantages over traditional multistage approaches. Immediate activation of transferred muscles reduces the risk of adhesions, facilitates relearning, avoids adverse effects of immobilization, and enhances functional recovery. Transfer of axillary, musculocutaneous, and radial nerve fascicles from above the spinal cord injury are effective and promising options to enhance motor outcome and sensory protection, especially in groups with limited resources. Improved communication between medical disciplines, therapists, patients, and their relatives should help that more individuals can benefit from these advances and could empower many thousands tetraplegic individuals "to take life into their own hands" and live more independently. Copyright © 2015 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

  15. Scabies: A clinical update.

    Science.gov (United States)

    Hardy, Myra; Engelman, Daniel; Steer, Andrew

    2017-01-01

    Scabies is a common, yet neglected, skin disease. Scabies occurs across Australia, but most frequently in socioeconomically disadvantaged populations in tropical regions, including in remote Aboriginal and Torres Strait Islander communities. In temperate settings, the disease clusters in institutional care facilities. The objective of this article is to provide updates on the clinical diagnosis and treatment approaches for scabies in Australia. Clinical examination remains the mainstay of diagnosis, although dermatoscopy is a useful adjunct. Scabies presents with severe itch and a papular rash, with a predilection for the hands, feet and genitalia. The distribution may be more widespread in infants and older people. Secondary bacterial infection is also common in patients with scabies. Crusted scabies is a rare but highly infectious variant. Topical permethrin is highly effective for individual treatment, but less practical for treatment of asymptomatic contacts and control of outbreaks. Oral ivermectin is a safe and effective alternative, and is now listed on the Pharmaceutical Benefits Scheme as a third-line treatment.

  16. Updates on obesity pharmacotherapy.

    Science.gov (United States)

    Velazquez, Amanda; Apovian, Caroline M

    2018-01-01

    Obesity is a chronic, relapsing disease that necessitates a multidisciplinary approach to management. Behavioral changes are the foundation to management, but adjunctive therapy is often warranted, including pharmacologic therapies and/or bariatric surgery. Until recently, treatment options included only short-term therapy (≤12 weeks), and paths beyond that schedule were challenging, as knowledge of the biology of obesity was lacking. With increased recognition of obesity as a chronic, complex medical disease, newer agents have been approved as long-term therapy, and the cornerstone of treatment is chronic behavior and lifestyle change. In the last decade, the Food and Drug Administration (FDA) has approved several new weight loss medications for the chronic management of obesity. In this review paper, we provide the latest updates on obesity pharmacotherapy. The main areas we will cover include (1) pharmacological management of obesity, (2) a review of FDA-approved weight loss medications, (3) comanagement of obesity and its metabolic sequelae (type 2 diabetes mellitus, hypertension, and dyslipidemia), and (4) obesity-centric prescribing for mental illness, neurological disorders, and contraceptive planning. © 2018 New York Academy of Sciences.

  17. Peritoneal dialysis update 1994.

    Directory of Open Access Journals (Sweden)

    Nolph K

    1994-07-01

    Full Text Available Each year there are over 400 papers published in the field of peritoneal dialysis. In this review I have touched on only a few highlights of some of the more active areas of investigation and development. The advances in controlling peritonitis rates with the Y-set have been dramatic and have resulted in peritonitis rates in many centers less than one episode per 24 patient months. Technique survivals have also improved with lower peritonitis rates. The enormous literature on new approaches to treatment and new understandings of host defenses are beyond the scope of this review. There are also many advances in peritoneal access. We now have many new types of catheters under investigation such as the Swan-Neck Missouri catheter and the Moncrief-Popovich catheter, with complete burial of the catheter until eventual externalization for CAPD training. There have been major advances in understanding the normal healing of exit sites and the early diagnosis and treatment of exit-site infections. All the extensive literature on catheter development in the management of exit sites will be reviewed elsewhere. I have focused primarily on an update of worldwide demographics, some of the new findings in peritoneal transport, the use of low-calcium solutions, experiences with EPO, new thinking about adequacy and nutrition, and finally, on recent comparisons of CAPD and hemodialysis.

  18. Research

    African Journals Online (AJOL)

    abp

    Research Team in Maternal and Child Health and Nutrition, Mohammed V. University, Rabat, Morocco. Key words: Breast cancer, risk factor, case-control study. Received: 04/01/2016 - Accepted: 17/03/2016 - Published: 06/05/2016. Abstract.

  19. Research

    Science.gov (United States)

    Mathematics Teaching, 1973

    1973-01-01

    Implications for teachers from Piagetian-oriented piagetian-oriented research on problem solving reported in an article by Eleanor Duckworth are presented. Edward de Bono's Children Solve Problems,'' a collection of examples, is also discussed. (MS)

  20. Research

    African Journals Online (AJOL)

    their academic performance, capabilities and functionings. At a tertiary educational level ... Research indicates that academic stressors, living circumstances, working conditions and where students undertake leisure activities affect academic performance .... Insufficient sleep, mild exhaustion, poor eating habits and little ...

  1. Research

    International Nuclear Information System (INIS)

    1999-01-01

    Subjects covered in this section are: (1) PCAST panel promotes energy research cooperation; (2) Letter issued by ANS urges funding balance in FFTF restart consideration and (3) FESAC panel releases report on priorities and balance

  2. Coxarthrosis - an update; Koxarthrose - ein Update

    Energy Technology Data Exchange (ETDEWEB)

    Imhof, H.; Noebauer-Huhmann, I.; Trattnig, S. [Medizinische Universitaet Wien, Klinik fuer Radiodiagnostik, Wien (Austria)

    2009-05-15

    Degenerative osteoarthritis of the hip joint (coxarthrosis) is the most common disease of the hip joint in adults. The diagnosis is based on a combination of radiographic findings and characteristic clinical symptoms. The lack of a radiographic consensus definition has seemingly resulted in a variation of the published incidences and prevalence of degenerative osteoarthritis of the hip joint. The chronological sequence of degeneration includes the following basic symptoms on conventional radiographs and CT: joint space narrowing, development of osteophytes, subchondral demineralisation/sclerosis and cyst formation, as well as loose bodies, joint malalignment and deformity. MR imaging allows additional visualization of early symptoms and/or activity signs such as cartilage edema, cartilage tears and defects, subchondral bone marrow edema, synovial edema and thickening, joint effusion and muscle atrophy. The scientific dispute concerns the significance of (minimal) joint malalignment (e.g. impingement, dysplasia etc.) and forms of malpositioning which as possible prearthrosis have a high probability of leading to degenerative osteoarthritis. Moreover, without any question, the preservation of joint containment and gender differences are important additional basic diagnostic principles, which have gained great interest in recent years. In research different MR procedures such as Na and H spectroscopy, T2*-mapping etc. with ultrahigh field MR allow cartilage metabolism and its changes in early degenerative osteoarthritis (''biochemical imaging'') to be studied. There is no doubt that even in a few years new profound knowledge is to be expected in this field. (orig.) [German] Die Hueftgelenkarthrose ist im Erwachsenenalter die haeufigste Erkrankung des Hueftgelenks. Die fehlende Konsensusdefinition dieser Erkrankung fuehrt zu einer scheinbar breiten Varianz bzgl. Inzidenz und Praevalenz. Die Diagnose wird aufgrund des radiologischen Befundes und der

  3. A research update for the Stuttgart National Aquaculture Research Center

    Science.gov (United States)

    Aquaculture (fish farming) has played an ever-increasing role in providing people with fish, shrimp, and shellfish. Aquaculture is currently the fastest growing sector of global food production and in 2016 totaled 90 million tons valued at $180 billion. The production of food-fish from aquaculture...

  4. Differential elliptic flow of identified hadrons and constituent quark number scaling at the GSI Facility for Antiproton and Ion Research (FAIR)

    International Nuclear Information System (INIS)

    Bhaduri, Partha Pratim; Chattopadhyay, Subhasis

    2010-01-01

    Differential elliptic flow v 2 (p T ) for identified hadrons is investigated in the FAIR energy regime, employing a hadronic-string transport model (UrQMD) as well as a partonic transport model (AMPT). It is observed that both models show a mass ordering of v 2 at low p T and a switch-over resulting in a baryon-meson crossing at intermediate p T . AMPT generates higher v 2 values compared to UrQMD. In addition, constituent quark number scaling behavior of elliptic flow is addressed. Scaling behavior in terms of the transverse momentum p T is found to be absent for both the partonic and the hadronic model. However, UrQMD and AMPT with a string melting scenario do exhibit an NCQ scaling of v 2 to varying degrees, with respect to the transverse kinetic energy KE T . But the default AMPT, where partonic scatterings are not included, does not show any considerable scaling behavior. A variable α is defined to quantify the degree of KE T scaling. We found that UrQMD gives better scaling than AMPT at FAIR.

  5. NRC review of Electric Power Research Institute's advanced light water reactor utility requirements document. Passive plant designs, chapters 2-13, project number 669

    International Nuclear Information System (INIS)

    1994-08-01

    The Electric Power Research Institute (EPRI) is preparing a compendium of technical requirements, referred to as the open-quotes Advanced Light Water Reactor [ALWR] Utility Requirements Documentclose quotes, that is acceptable to the design of an ALWR power plant. When completed, this document is intended to be a comprehensive statement of utility requirements for the design, construction, and performance of an ALWR power plant for the 1990s and beyond. The Requirements Document consists of three volumes. Volume I, open-quotes ALWR Policy and Summary of Top-Tier Requirementsclose quotes, is a management-level synopsis of the Requirements Document, including the design objectives and philosophy, the overall physical configuration and features of a future nuclear plant design, and the steps necessary to take the proposed ALWR design criteria beyond the conceptual design state to a completed, functioning power plant. Volume II consists of 13 chapters and contains utility design requirements for an evolutionary nuclear power plant [approximately 1350 megawatts-electric (MWe)]. Volume III contains utility design requirements for nuclear plants for which passive features will be used in their designs (approximately 600 MWe). In April 1992, the staff of the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, issued Volume 1 and Volume 2 (Parts 1 and 2) of its safety evaluation report (SER) to document the results of its review of Volumes 1 and 2 of the Requirements Document. Volume 1, open-quotes NRC Review of Electric Power Research Institute's Advanced Light Water Reactor Utility Requirements Document - Program Summaryclose quotes, provided a discussion of the overall purpose and scope of the Requirements Document, the background of the staff's review, the review approach used by the staff, and a summary of the policy and technical issues raised by the staff during its review

  6. NRC review of Electric Power Research Institute`s advanced light water reactor utility requirements document. Passive plant designs, chapter 1, project number 669

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-01

    The Electric Power Research Institute (EPRI) is preparing a compendium of technical requirements, referred to as the {open_quotes}Advanced Light Water Reactor [ALWR] Utility Requirements Document{close_quotes}, that is acceptable to the design of an ALWR power plant. When completed, this document is intended to be a comprehensive statement of utility requirements for the design, construction, and performance of an ALWR power plant for the 1990s and beyond. The Requirements Document consists of three volumes. Volume 1, {open_quotes}ALWR Policy and Summary of Top-Tier Requirements{close_quotes}, is a management-level synopsis of the Requirements Document, including the design objectives and philosophy, the overall physical configuration and features of a future nuclear plant design, and the steps necessary to take the proposed ALWR design criteria beyond the conceptual design state to a completed, functioning power plant. Volume II consists of 13 chapters and contains utility design requirements for an evolutionary nuclear power plant [approximately 1350 megawatts-electric (MWe)]. Volume III contains utility design requirements for nuclear plants for which passive features will be used in their designs (approximately 600 MWe). In April 1992, the staff of the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, issued Volume 1 and Volume 2 (Parts 1 and 2) of its safety evaluation report (SER) to document the results of its review of Volumes 1 and 2 of the Requirements Document. Volume 1, {open_quotes}NRC Review of Electric Power Research Institute`s Advanced Light Water Reactor Utility Requirements Document - Program Summary{close_quotes}, provided a discussion of the overall purpose and scope of the Requirements Document, the background of the staff`s review, the review approach used by the staff, and a summary of the policy and technical issues raised by the staff during its review.

  7. NRC review of Electric Power Research Institute`s advanced light water reactor utility requirements document. Passive plant designs, chapters 2-13, project number 669

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-01

    The Electric Power Research Institute (EPRI) is preparing a compendium of technical requirements, referred to as the {open_quotes}Advanced Light Water Reactor [ALWR] Utility Requirements Document{close_quotes}, that is acceptable to the design of an ALWR power plant. When completed, this document is intended to be a comprehensive statement of utility requirements for the design, construction, and performance of an ALWR power plant for the 1990s and beyond. The Requirements Document consists of three volumes. Volume I, {open_quotes}ALWR Policy and Summary of Top-Tier Requirements{close_quotes}, is a management-level synopsis of the Requirements Document, including the design objectives and philosophy, the overall physical configuration and features of a future nuclear plant design, and the steps necessary to take the proposed ALWR design criteria beyond the conceptual design state to a completed, functioning power plant. Volume II consists of 13 chapters and contains utility design requirements for an evolutionary nuclear power plant [approximately 1350 megawatts-electric (MWe)]. Volume III contains utility design requirements for nuclear plants for which passive features will be used in their designs (approximately 600 MWe). In April 1992, the staff of the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, issued Volume 1 and Volume 2 (Parts 1 and 2) of its safety evaluation report (SER) to document the results of its review of Volumes 1 and 2 of the Requirements Document. Volume 1, {open_quotes}NRC Review of Electric Power Research Institute`s Advanced Light Water Reactor Utility Requirements Document - Program Summary{close_quotes}, provided a discussion of the overall purpose and scope of the Requirements Document, the background of the staff`s review, the review approach used by the staff, and a summary of the policy and technical issues raised by the staff during its review.

  8. NRC review of Electric Power Research Institute's advanced light water reactor utility requirements document. Passive plant designs, chapter 1, project number 669

    International Nuclear Information System (INIS)

    1994-08-01

    The Electric Power Research Institute (EPRI) is preparing a compendium of technical requirements, referred to as the open-quotes Advanced Light Water Reactor [ALWR] Utility Requirements Documentclose quotes, that is acceptable to the design of an ALWR power plant. When completed, this document is intended to be a comprehensive statement of utility requirements for the design, construction, and performance of an ALWR power plant for the 1990s and beyond. The Requirements Document consists of three volumes. Volume 1, open-quotes ALWR Policy and Summary of Top-Tier Requirementsclose quotes, is a management-level synopsis of the Requirements Document, including the design objectives and philosophy, the overall physical configuration and features of a future nuclear plant design, and the steps necessary to take the proposed ALWR design criteria beyond the conceptual design state to a completed, functioning power plant. Volume II consists of 13 chapters and contains utility design requirements for an evolutionary nuclear power plant [approximately 1350 megawatts-electric (MWe)]. Volume III contains utility design requirements for nuclear plants for which passive features will be used in their designs (approximately 600 MWe). In April 1992, the staff of the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, issued Volume 1 and Volume 2 (Parts 1 and 2) of its safety evaluation report (SER) to document the results of its review of Volumes 1 and 2 of the Requirements Document. Volume 1, open-quotes NRC Review of Electric Power Research Institute's Advanced Light Water Reactor Utility Requirements Document - Program Summaryclose quotes, provided a discussion of the overall purpose and scope of the Requirements Document, the background of the staff's review, the review approach used by the staff, and a summary of the policy and technical issues raised by the staff during its review

  9. Genomics and Health Impact Update

    Science.gov (United States)

    ... Alzheimer’s Disease Autism Breast Cancer Cardiomyopathy Colorectal Cancer Diabetes Familial Hypercholesterolemia Heart Disease Hepatitis HIV/AIDS Influenza Listeriosis Lynch Syndrome Malaria Osteoporosis Sudden Death Tuberculosis Zika Virus Updates on Specific Topics Big Data ...

  10. Argonne Wakefield Accelerator Update '92

    International Nuclear Information System (INIS)

    Rosing, M.; Balka, L.; Chojnacki, E.; Gai, W.; Ho, C.; Konecny, R.; Power, J.; Schoessow, P.; Simpson, J.

    1992-01-01

    The Argonne Wakefield Accelerator (AWA) is an experiment designed to test various ideas related to wakefield technology. Construction is now underway for a 100 nC electron beam in December of 1992. This report updates this progress

  11. Autoimmune pancreatitis. An update; Autoimmunpankreatitis. Ein Update

    Energy Technology Data Exchange (ETDEWEB)

    Helmberger, T. [Klinikum Bogenhausen, Staedt. Klinikum, Institut fuer Diagnostische und Interventionelle Radiologie, Neuroradiologie und Nuklearmedizin, Muenchen (Germany)

    2016-04-15

    Autoimmune pancreatitis (AIP) is a rare disease, the pathophysiological understanding of which has been greatly improved over the last years. The most common form, type 1 AIP belongs to the IgG4-related diseases and must be distinguished from type 2 AIP, which is a much rarer entity associated with chronic inflammatory bowel disease. Clinically, there is an overlap with pancreatic cancer. Imaging and further criteria, such as serological and histological parameters are utilized for a differentiation between both entities in order to select the appropriate therapy and to avoid the small but ultimately unnecessary number of pancreatectomies. The diagnostics of AIP are complex, whereby the consensus criteria of the International Association of Pancreatology have become accepted as the parameters for discrimination. These encompass five cardinal criteria and one therapeutic criterion. By applying these criteria AIP can be diagnosed with a sensitivity of 84.9 %, a specificity of 100 % and an accuracy of 93.8 %. The diagnosis of AIP is accomplished by applying several parameters of which two relate to imaging. As for the routine diagnostics of the pancreas these are ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI). Important for the differential diagnosis is the exclusion of signs of local and remote tumor spread for which CT and MRI are established. The essential diagnostic parameter of histology necessitates sufficient sample material, which cannot usually be acquired by a fine needle biopsy. CT or MRI are the reference standard methods for identification of the optimal puncture site and imaging-assisted (TruCut) biopsy. In patients presenting with unspecific upper abdominal pain, painless jaundice combined with the suspicion of a pancreatic malignancy in imaging but a mismatch of secondary signs of malignancy, AIP should also be considered as a differential diagnosis. As the diagnosis of AIP only partially relies on imaging radiologists also

  12. Efficient Synthesis of Network Updates

    Science.gov (United States)

    2015-06-17

    Pavol Černý CU Boulder pavol.cerny@colorado.edu Nate Foster Cornell University jnfoster@cs.cornell.edu Abstract Software-defined networking ( SDN ...is revolutionizing the net- working industry, but current SDN programming platforms do not provide automated mechanisms for updating global...configurations on the fly. Implementing updates by hand is challenging for SDN programmers because networks are distributed systems with hun- dreds or thousands

  13. Communication technology update and fundamentals

    CERN Document Server

    Grant, August E

    2010-01-01

    New communication technologies are being introduced at an astonishing rate. Making sense of these technologies is increasingly difficult. Communication Technology Update and Fundamentals is the single best source for the latest developments, trends, and issues in communication technology. Featuring the fundamental framework along with the history and background of communication technologies, Communication Technology Update and Fundamentals, 12th edition helps you stay ahead of these ever-changing and emerging technologies.As always, every chapter ha

  14. Communication technology update and fundamentals

    CERN Document Server

    Grant, August E

    2008-01-01

    New communication technologies are being introduced at an astonishing rate. Making sense of these technologies is increasingly difficult. Communication Technology Update is the single best source for the latest developments, trends, and issues in communication technology. Now in its 11th edition, Communication Technology Update has become an indispensable information resource for business, government, and academia. As always, every chapter has been completely rewritten to reflect the latest developments and market statistics, and now covers mobile computing, dig

  15. Decentralized Consistent Updates in SDN

    KAUST Repository

    Nguyen, Thanh Dang

    2017-04-10

    We present ez-Segway, a decentralized mechanism to consistently and quickly update the network state while preventing forwarding anomalies (loops and blackholes) and avoiding link congestion. In our design, the centralized SDN controller only pre-computes information needed by the switches during the update execution. This information is distributed to the switches, which use partial knowledge and direct message passing to efficiently realize the update. This separation of concerns has the key benefit of improving update performance as the communication and computation bottlenecks at the controller are removed. Our evaluations via network emulations and large-scale simulations demonstrate the efficiency of ez-Segway, which compared to a centralized approach, improves network update times by up to 45% and 57% at the median and the 99th percentile, respectively. A deployment of a system prototype in a real OpenFlow switch and an implementation in P4 demonstrate the feasibility and low overhead of implementing simple network update functionality within switches.

  16. Plug and Play Solar Power: Simplifying the Integration of Solar Energy in Hybrid Applications; Cooperative Research and Development Final Report, CRADA Number CRD-13-523

    Energy Technology Data Exchange (ETDEWEB)

    Lundstrom, Blake R. [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-07-05

    The Commonwealth Scientific and Industrial Research Organisation (CSIRO) is Australia's national science agency. CSIRO received funding from the Australian Solar Institute (ASI) for the United States-Australia Solar Energy Collaboration (USASEC) project 1-USO032 Plug and Play Solar Power: Simplifying the Integration of Solar Energy in Hybrid Applications (Broader Project). The Australian Solar Institute (ASI) operated from August 2009 to December 2012 before being merged into the Australian Renewable Energy Agency (ARENA). The Broader Project sought to simplify the integration, accelerate the deployment, and lower the cost of solar energy in hybrid distributed generation applications by creating plug and play solar technology. CSIRO worked with the National Renewable Energy Laboratory (NREL) as set out in a Joint Work Statement to review communications protocols relevant to plug-and-play technology and perform prototype testing in its Energy System Integration Facility (ESIF). For the avoidance of doubt, this CRADA did not cover the whole of the Broader Project and only related to the work described in the Joint Work Statement, which was carried out by NREL.

  17. Nova Scotia electricity update

    International Nuclear Information System (INIS)

    Crandlemire, A.L.

    2004-01-01

    This paper provides an update of electricity issues concerning Nova Scotia such as supply, capacity, emission commitments, as well as co-generation and the Electricity Marketplace Governance Committee (EMGC). The goals of the strategy were reliability combined with competitive prices and greater environmental responsibility. The scope of these objectives included new capacity, transmission, renewables and co-generation. Other objectives included encouraging wholesale market competition; meeting reciprocity requirements; and a 50 MW renewable energy target. Recommendations of the EMGC included wholesale market competition; a broader market scope with a cost benefit analysis; Open Access Transmission Tariff (OATT); a scheduling and information system; network integration and a point to point service; and a separation of transmission and generation business units. Other recommendations included an open competitive process for new generation; a consideration of emissions and overall efficiency; a Renewable Energy Portfolio Standard (RPS) to start in 2006; the separation of RPS tags from electricity; and net metering of renewables. These recommendations were accepted in 2003, followed by the new Electricity Act in 2004, which made OATT mandatory, established RPS and opened to the wholesale market. Capacity at present was considered to be tight, with preparations for the new regulations under way. Reductions in air pollution were reported at 25 per cent, with renewable energy projects such as 2 windmills currently under way, as well as various other projects. Opportunities for provincial Atlantic cooperation were identified as being management of reserve requirements; trading of lowest cost electricity; new generation on a regional scale; stronger transmission ties; a system operator; a regional approach to RPS; regional management of air emissions; and regional opportunities for Carbon dioxide reductions. tabs., figs

  18. NB market update

    International Nuclear Information System (INIS)

    Marshall, W. K.

    2004-01-01

    The 2004 New Brunswick proclamation introduced several changes to the industry. This paper presents an update of the current New Brunswick electricity market from the perspective of the recently created New Brunswick System Operator (NBSO). A comparison was made between the modified industry and the previous industry structure. Significant changes included: corporate restructuring and market implementation; the formation of the independent system operator; and an increase in Public Utilities Board regulatory authority. The main objectives of the NBSO were reviewed, including its intention to reliably plan and operate the integrated power system as well as facilitating and operating the electricity market. Details of directors and officers were provided along with a list of legislated functions which included entering agreements with transmitters; provision and procurement of ancillary services; maintenance of integrated system; coordination of external activities; participation with standards authorities; planning and development of transmission; and the facilitation of a competitive market. An outline of the NBSO, Transco and Public Utilities Board relationships were presented. Details of the market advisory committee were outlined, with information concerning contracts, operations and services agreements. Transmission and ancillary services were also discussed, as well as issues concerning interruptible load agreements. A chart of the New Brunswick electricity market structure was presented, along with a market overview including details of capacity, ancillary services and suppliers. Market rules and amendments were presented, as well as market participation guides. Details of generation resource adequacy requirements and the imposition of penalties were outlined. Scheduling and dispatch issues were overviewed, as well as settlement processes, inputs and their sources, including settlements for variances. Future development possibilities included an expansion of

  19. Herpes Labialis: An Update.

    Science.gov (United States)

    Leung, Alexander K C; Barankin, Benjamin

    2017-01-01

    Herpes labialis is characterized by recurrent vesicular eruptions primarily on the lips and perioral skin. The condition is contagious, can cause significant discomfort/pain, and can have an adverse effect on the quality of life. To update the evaluation and treatment of herpes labialis. A PubMed search was completed in Clinical Queries using the key term "herpes labialis". Patents were searched using the key term "herpes labialis" from www.freepatentsonline.com. The diagnosis of herpes labialis is mainly clinical based on classic grouped lesions (papules, vesicles, ulcers) on the lip. Antiviral therapy shortens the duration of pain and discomfort, hastens healing, and reduces viral shedding. Thus, episodic treatment is warranted, especially if the patient desires treatment for cosmetic purposes or for relief of pain. Such treatment needs to be initiated promptly, ideally in the prodromal stage and no later than 48 hours from the onset of lesions to achieve optimal results. Chronic suppressive therapy with oral antiviral agents should be considered for patients with severe or frequent (six or more episodes per year) recurrences. Recent patents related to the management of herpes labialis are also discussed. For episodic treatment, oral antiviral agents, such as acyclovir (Zovirax), valacyclovir (Valtrex) and famciclovir (Famvir), are superior to topical antiviral therapy. Valacyclovir and famciclovir have greater oral bioavailability and are better absorbed than acyclovir, require less frequent dosing, but are more expensive and are not approved for children. Topical antiviral agents such as 5% acyclovir cream/ointment (Zovirax) ± hydrocortisone (Xerese), 1% penciclovir (Denavir) cream, and 50 mg Buccal Adhesive Tablet (ABT-50 mg) can also be used for episodic treatment of herpes labialis. These topical agents are not effective in the prevention of recurrent herpes labialis. For chronic daily suppressive therapy, oral antivirals are the treatment of choice

  20. Updating a systematic review – what difference did it make? Case study of nicotine replacement therapy

    Directory of Open Access Journals (Sweden)

    Lancaster Tim

    2001-11-01

    Full Text Available Abstract Aims To examine the effect of updating a systematic review of nicotine replacement therapy on its contents and conclusions. Methods We examined the effects of regular updating of a systematic review of nicotine replacement therapy for smoking cessation. We considered two outcomes. First, we assessed the effect of adding new data to meta-analyses, comparing results in 2000 with the results in 1994. Second, we assessed qualitatively the ways inwhich the nature of the questions addressed by the review had changed between the two dates. For the first outcome, we compared the number of trials, the pooled estimate of effect using the odds ratio, and the results of pre-specified subgroup analyses, for nicotine gum and patch separately. Using a test for interaction, we assessed whether differences between estimates were statistically significant. Results There were ten new trials of nicotine gum between 1994 and 2000, and the meta-analytic effect changed little. For the nicotine patch the number of trials increased from 9 to 30, and the meta-analytic effect fell from 2.07 (95% CI 1.64 – 2.62 to 1.73 (95% CI 1.56 – 1.93. Apparent differences in relative effect in sub-groups found in 1994 were not found in 2000. The updated systematic review addressed a number of questions not identified in the original version. Conclusions Updating the meta-analyses lead to a more precise estimate of the likely effect of the nicotine patch, but the clinical message was unchanged. Further placebo controlled NRT trials are not likely to add to the evidence base. It is questionable whether updating the meta-analyses to include them is worthwhile. The content of the systematic review has, however, changed, with the addition of data addressing questions not considered in the original review. There is a tension between the principle of identifying the important questions prior to conducting a review, and keeping the review up to date as primary research identifies

  1. Research

    African Journals Online (AJOL)

    ebutamanya

    2016-03-24

    Mar 24, 2016 ... national non-governmental organization (NGO) ”Arc en Ciel„. This. NGO, which is familiar with research activities, identified the MSM community leaders in the .... whom there is an emotional attachment) in both homosexual and heterosexual populations [14, 19]. Like other reports from. Cameroon [19] and ...

  2. Research

    African Journals Online (AJOL)

    raoul

    2012-01-11

    Jan 11, 2012 ... 1MPH Programme, Department of Community Medicine, University of Zimbabwe, Zimbabwe, 2Department of Epidemiology and Disease Control,. Ministry ... Pan African Medical Journal. 2012; 11: ..... Mufuta Tshimanga: Had oversight of all the stages of the research and critically reviewed the final draft for.

  3. Research

    African Journals Online (AJOL)

    raoul

    2011-08-25

    Aug 25, 2011 ... euthanasia were also queried. Data was analyzed using Epidata, SPSS 16.0 and Microsoft Excel. Results: Thirty-eight (97.4%) of thirty-nine institutions reported using animals for education and/or research. Thirty (76.9%) institutions reported using analgesics or anesthetics on a regular basis. Thirteen ...

  4. Research

    African Journals Online (AJOL)

    abp

    2016-02-01

    Feb 1, 2016 ... University Hospital, DK-5000 Odense, Denmark, 3Center for Global Health, Institute of Clinical Research, University of Southern Denmark, DK-5000. Odense .... BHP is a Danish-Guinean Demographic Surveillance Site with a study-area .... variables such as age groups, previous military duty, history of.

  5. Research

    African Journals Online (AJOL)

    Research. May 2016, Vol. 8, No. 1 AJHPE 37. Students who enrol in occupational therapy (OT) at the. University of Kwa Zulu-Natal (UKZN), Durban, South Africa ... The latter may include becoming familiar with the disintegrating social systems in primary .... They also lacked the skills needed to adapt sessions and failed to ...

  6. Research

    African Journals Online (AJOL)

    raoul

    2011-12-14

    Dec 14, 2011 ... skills through hands-on application of epidemiology to real public health issues. For the most part, residents carry out research projects in priority areas of the districts they are attached, often under direct supervision of the local or provincial health leaders [2]. In Africa, these programs formed a networking ...

  7. Research

    African Journals Online (AJOL)

    abp

    2014-03-21

    Mar 21, 2014 ... Published in partnership with the African Field Epidemiology Network (AFENET). (www.afenet.net). Research ... were intervention strategies for primary health care delivery at the district and community levels ..... to be a gap between policy formation and implementation as only immunization services are.

  8. Research

    African Journals Online (AJOL)

    abp

    2013-03-05

    Mar 5, 2013 ... food market) [10]. There are few studies that provide data on NCDs from Africa and these are mainly from South Africa [11]. In the same vein, research efforts in The .... males, in view of the relationships between obesity, physical inactivity and .... pronged intervention strategies-epidemiological surveillance,.

  9. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-11-23

    Nov 23, 2015 ... 1Amref Health Africa, P.O Box 2773 Dar es Salaam, Tanzania, 2Kilimanjaro Reproductive Health Program, Moshi, Tanzania, 3Population Services. International, Nairobi .... testing, HIV testing history and HIV test results. ..... due to differences in the research designs, nature of population and sample size ...

  10. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-06-22

    Jun 22, 2015 ... collaboration with Makerere University, School of Public Health. We acknowledge The Family Health Research and Development Centre. (FHRDC) Uganda. Supported by Bill & Melinda Gates Institute for. Population & Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, ...

  11. Research

    African Journals Online (AJOL)

    abp

    2016-04-14

    Apr 14, 2016 ... Methods. Study design: A mixed method cross-sectional design using both quantitative and qualitative research methods as described by. Hanson et al [33] was employed. Settings: The study was based on data from the midterm evaluation that was conducted between August-December 2012 involving ...

  12. Research

    African Journals Online (AJOL)

    the importance of the learning setting (curriculum context), a capability approach to learning (the process), and the production of expert generalists. (the outcome) .... including communication, learning transfer, teamwork, self-confidence, and reciprocal and effective practice.[6-8] Research also shows that PAL provides a.

  13. Research

    African Journals Online (AJOL)

    raoul

    2011-11-14

    Nov 14, 2011 ... Data were collected between February and March 2010 using a questionnaire, designed by the researcher. It comprised two sections; the ..... Bazant ES, Koenig MA, Fotso J-C, Mills S. Women's Use of Private and Government Health Facilities for Childbirth in Nairobi's Informal. Settlements. Stud Fam Plann ...

  14. Research

    African Journals Online (AJOL)

    Research. This article provides a detailed description of the development of an evaluation matrix that represents the organising structure for evaluating the impact of the interdisciplinary health-promotion course on multiple stakeholders. The evaluation was designed to answer the questions relating to the perceptions and ...

  15. Research

    African Journals Online (AJOL)

    2017-03-18

    Mar 18, 2017 ... promote CPD by working in partnership with employers, academic institutions ... SORK, employers and institutions of higher education all have a responsibility towards the culture of lifelong learning. As the ... further approved by the Higher Degrees and Research Ethics Committees of the University of ...

  16. Research

    African Journals Online (AJOL)

    tions as their reality.[14]. Research context. At Stellenbosch University (SU), Cape Town,. SA, final-year physiotherapy students each spend. 6 weeks at a community site learning to integrate and apply the principles of PHC and community- based rehabilitation. Approximately 5 - 10 clients are seen in their homes per week.

  17. Research

    African Journals Online (AJOL)

    the classroom.[9] Cognitive learning is achieved when students can make connections among and interpret different aspects of a subject to apply what they have learned in other fields of ... the effect of the field trips on the students' perceptions. ... researcher in higher education teaching and learning facilitated the data-.

  18. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-12-02

    Dec 2, 2015 ... It is an important aspect of quality of life which is often neglected by people in this age group, attending physicians and the society as a whole. The study was aimed at determining ... or a trained research assistant for those who could neither read nor write. Consenting individuals above this age who have ...

  19. Research

    African Journals Online (AJOL)

    abp

    2014-01-31

    Jan 31, 2014 ... by Hazarika in a population-based study in India. The researcher noted that patients' preference to the private health facilities was due mainly to their dissatisfaction with the services in the public health facilities [11]. Furthermore, the quality of the services in the private health facilities could also be a major ...

  20. Research

    African Journals Online (AJOL)

    abp

    2017-11-30

    Nov 30, 2017 ... Authors' contributions. All the authors have read and agreed to the final manuscript. Acknowledgments. The author was supported by a postdoctoral fellowship awarded by the South African National Research Foundation (NRF). The content of this manuscript does not necessarily represent the official views.