WorldWideScience

Sample records for research tools included

  1. A micromanipulation cell including a tool changer

    Science.gov (United States)

    Clévy, Cédric; Hubert, Arnaud; Agnus, Joël; Chaillet, Nicolas

    2005-10-01

    This paper deals with the design, fabrication and characterization of a tool changer for micromanipulation cells. This tool changer is part of a manipulation cell including a three linear axes robot and a piezoelectric microgripper. All these parts are designed to perform micromanipulation tasks in confined spaces such as a microfactory or in the chamber of a scanning electron microscope (SEM). The tool changer principle is to fix a pair of tools (i.e. the gripper tips) either on the tips of the microgripper actuator (piezoceramic bulk) or on a tool magazine. The temperature control of a thermal glue enables one to fix or release this pair of tools. Liquefaction and solidification are generated by surface mounted device (SMD) resistances fixed on the surface of the actuator or magazine. Based on this principle, the tool changer can be adapted to other kinds of micromanipulation cells. Hundreds of automatic tool exchanges were performed with a maximum positioning error between two consecutive tool exchanges of 3.2 µm, 2.3 µm and 2.8 µm on the X, Y and Z axes respectively (Z refers to the vertical axis). Finally, temperature measurements achieved under atmospheric pressure and in a vacuum environment and pressure measurements confirm the possibility of using this device in the air as well as in a SEM.

  2. Research tools | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Through training materials and guides, we aim to build skills and knowledge to enhance the quality of development research. We also offer free access to our database of funded research projects, known as IDRIS+, and our digital library. Our research tools include. Guide to research databases at IDRC: How to access and ...

  3. INTELLECTUAL PROPERTY RIGHTS ISSUES FOR RESEARCH TOOLS IN BIOTECHNOLOGY RESEARCH

    Directory of Open Access Journals (Sweden)

    Rekha Chaturvedi

    2015-09-01

    Full Text Available The research tools refer to the resources researchers need to use in experimental work. In Biotechnology, these can include cell lines, monoclonal antibodies, reagents, animal models, growth factors, combinatorial chemistry libraries, drug and drug targets, clones and cloning tools (such as PCR, method, laboratory equipment and machines, database and computer software. Research tools therefore serve as basis for upstream research to improve the present product or process. There are several challenges in the way of using patented research tools. IP issues with regard to research tools are important and may sometime pose hindrance for researchers. Hence in the case of patented research tools, IPR issues can compose a major hurdle for technology development. In majority instances research tools are permitted through MTAs for academic research and for imparting education. TRIPS provides a provision for exception to patent rights for experimental use of patented technology in scientific research and several countries including India have included this provision in their patent legislation. For commercially important work, licensing of research tools can be based on royalty or one time lump sum payment. Some patent owners of important high-end research tools for development of platform technology create problems in licensing which can impede research. Usually cost of a commercially available research tool is built up in its price.

  4. A tool for standardized collector performance calculations including PVT

    DEFF Research Database (Denmark)

    Perers, Bengt; Kovacs, Peter; Olsson, Marcus

    2012-01-01

    A tool for standardized calculation of solar collector performance has been developed in cooperation between SP Technical Research Institute of Sweden, DTU Denmark and SERC Dalarna University. The tool is designed to calculate the annual performance of solar collectors at representative locations...

  5. "Research Tools": Tools for supporting research and publications

    OpenAIRE

    Ebrahim, Nader Ale

    2014-01-01

    Research Tools” can be defined as vehicles that broadly facilitate research and related activities. “Research Tools” enable researchers to collect, organize, analyze, visualize and publicized research outputs. Dr. Nader has collected over 700 tools that enable students to follow the correct path in research and to ultimately produce high-quality research outputs with more accuracy and efficiency. It is assembled as an interactive Web-based mind map, titled “Research Tools”, which is updated ...

  6. A tool for standardized collector performance calculations including PVT

    DEFF Research Database (Denmark)

    Perers, Bengt; Kovacs, Peter; Olsson, Marcus

    2012-01-01

    A tool for standardized calculation of solar collector performance has been developed in cooperation between SP Technical Research Institute of Sweden, DTU Denmark and SERC Dalarna University. The tool is designed to calculate the annual performance of solar collectors at representative locations...... can be tested and modeled as a thermal collector, when the PV electric part is active with an MPP tracker in operation. The thermal collector parameters from this operation mode are used for the PVT calculations....

  7. Community Assessment Tool for Public Health Emergencies Including Pandemic Influenza

    Energy Technology Data Exchange (ETDEWEB)

    ORAU' s Oak Ridge Institute for Science Education (HCTT-CHE)

    2011-04-14

    The Community Assessment Tool (CAT) for Public Health Emergencies Including Pandemic Influenza (hereafter referred to as the CAT) was developed as a result of feedback received from several communities. These communities participated in workshops focused on influenza pandemic planning and response. The 2008 through 2011 workshops were sponsored by the Centers for Disease Control and Prevention (CDC). Feedback during those workshops indicated the need for a tool that a community can use to assess its readiness for a disaster - readiness from a total healthcare perspective, not just hospitals, but the whole healthcare system. The CAT intends to do just that - help strengthen existing preparedness plans by allowing the healthcare system and other agencies to work together during an influenza pandemic. It helps reveal each core agency partners (sectors) capabilities and resources, and highlights cases of the same vendors being used for resource supplies (e.g., personal protective equipment [PPE] and oxygen) by the partners (e.g., public health departments, clinics, or hospitals). The CAT also addresses gaps in the community's capabilities or potential shortages in resources. This tool has been reviewed by a variety of key subject matter experts from federal, state, and local agencies and organizations. It also has been piloted with various communities that consist of different population sizes, to include large urban to small rural communities.

  8. Community Assessment Tool for Public Health Emergencies Including Pandemic Influenza

    Energy Technology Data Exchange (ETDEWEB)

    HCTT-CHE

    2011-04-14

    The Community Assessment Tool (CAT) for Public Health Emergencies Including Pandemic Influenza (hereafter referred to as the CAT) was developed as a result of feedback received from several communities. These communities participated in workshops focused on influenza pandemic planning and response. The 2008 through 2011 workshops were sponsored by the Centers for Disease Control and Prevention (CDC). Feedback during those workshops indicated the need for a tool that a community can use to assess its readiness for a disaster—readiness from a total healthcare perspective, not just hospitals, but the whole healthcare system. The CAT intends to do just that—help strengthen existing preparedness plans by allowing the healthcare system and other agencies to work together during an influenza pandemic. It helps reveal each core agency partners' (sectors) capabilities and resources, and highlights cases of the same vendors being used for resource supplies (e.g., personal protective equipment [PPE] and oxygen) by the partners (e.g., public health departments, clinics, or hospitals). The CAT also addresses gaps in the community's capabilities or potential shortages in resources. While the purpose of the CAT is to further prepare the community for an influenza pandemic, its framework is an extension of the traditional all-hazards approach to planning and preparedness. As such, the information gathered by the tool is useful in preparation for most widespread public health emergencies. This tool is primarily intended for use by those involved in healthcare emergency preparedness (e.g., community planners, community disaster preparedness coordinators, 9-1-1 directors, hospital emergency preparedness coordinators). It is divided into sections based on the core agency partners, which may be involved in the community's influenza pandemic influenza response.

  9. Tools for voltage stability analysis, including a probabilistic approach

    Energy Technology Data Exchange (ETDEWEB)

    Vieira Filho, X.; Martins, N.; Bianco, A.; Pinto, H.J.C.P. [Centro de Pesquisas de Energia Eletrica (CEPEL), Rio de Janeiro, RJ (Brazil); Pereira, M.V.F. [Power System Research (PSR), Inc., Rio de Janeiro, RJ (Brazil); Gomes, P.; Santos, M.G. dos [ELETROBRAS, Rio de Janeiro, RJ (Brazil)

    1994-12-31

    This paper reviews some voltage stability analysis tools that are being used or envisioned for expansion and operational planning studies in the Brazilian system, as well as, their applications. The paper also shows that deterministic tools can be linked together in a probabilistic framework, so as to provide complementary help to the analyst in choosing the most adequate operation strategies, or the best planning solutions for a given system. (author) 43 refs., 8 figs., 8 tabs.

  10. TOOLS TO INCLUDE BLIND STUDENTS IN SCHOOL BUILDING PERFORMANCE ASSESSMENTS

    Directory of Open Access Journals (Sweden)

    Tania Pietzschke Abate

    2016-05-01

    Full Text Available This article discusses the design of data collection instruments that include the opinions of blind students, in accordance with the principles of Universal Design (UD. The aim of this study is to understand the importance of adapting data collection instruments for the inclusion of disabled persons in field research in Architecture and Design, among other fields. The data collection instruments developed were a play interview with a tactile map and a 3D survey with the use of tactile models. These instruments sought to assess the school environment experienced by blind students. The study involved students from the early years of a school for the blind who had not yet mastered the Braille system. The participation of these students was evaluated. A multidisciplinary team consisting of architects, designers, educators, and psychologists lent support to the study. The results showed that the data collection instruments adapted to blind students were successful in making the group of authors examine questions regarding UD. An analysis of the participatory phase showed that the limitations resulting from blindness determine the specificities in the adaptation and implementation process of the instruments in schools. Practical recommendations for future studies related to instruments in the UD thematic are presented. This approach is in line with the global trend of including disabled persons in society based on these users’ opinions concerning what was designed by architects and designers.

  11. Gradually including potential users: A tool to counter design exclusions.

    Science.gov (United States)

    Zitkus, Emilene; Langdon, Patrick; Clarkson, P John

    2018-01-01

    The paper describes an iterative development process used to understand the suitability of different inclusive design evaluation tools applied into design practices. At the end of this process, a tool named Inclusive Design Advisor was developed, combining data related to design features of small appliances with ergonomic task demands, anthropometric data and exclusion data. When auditing a new design the tool examines the exclusion that each design feature can cause, followed by objective recommendations directly related to its features. Interactively, it allows designers or clients to balance design changes with the exclusion caused. It presents the type of information that enables designers and clients to discuss user needs and make more inclusive design decisions. Copyright © 2017. Published by Elsevier Ltd.

  12. Software tool for portal dosimetry research.

    Science.gov (United States)

    Vial, P; Hunt, P; Greer, P B; Oliver, L; Baldock, C

    2008-09-01

    This paper describes a software tool developed for research into the use of an electronic portal imaging device (EPID) to verify dose for intensity modulated radiation therapy (IMRT) beams. A portal dose image prediction (PDIP) model that predicts the EPID response to IMRT beams has been implemented into a commercially available treatment planning system (TPS). The software tool described in this work was developed to modify the TPS PDIP model by incorporating correction factors into the predicted EPID image to account for the difference in EPID response to open beam radiation and multileaf collimator (MLC) transmitted radiation. The processes performed by the software tool include; i) read the MLC file and the PDIP from the TPS, ii) calculate the fraction of beam-on time that each point in the IMRT beam is shielded by MLC leaves, iii) interpolate correction factors from look-up tables, iv) create a corrected PDIP image from the product of the original PDIP and the correction factors and write the corrected image to file, v) display, analyse, and export various image datasets. The software tool was developed using the Microsoft Visual Studio.NET framework with the C# compiler. The operation of the software tool was validated. This software provided useful tools for EPID dosimetry research, and it is being utilised and further developed in ongoing EPID dosimetry and IMRT dosimetry projects.

  13. Including Everyone in Research: The Burton Street Research Group

    Science.gov (United States)

    Abell, Simon; Ashmore, Jackie; Wilson, Dorothy; Beart, Suzie; Brownley, Peter; Butcher, Adam; Clarke, Zara; Combes, Helen; Francis, Errol; Hayes, Stefan; Hemmingham, Ian; Hicks, Kerry; Ibraham, Amina; Kenyon, Elinor; Lee, Darren; McClimens, Alex; Collins, Michelle; Newton, John; Wilson, Dorothy

    2007-01-01

    In our paper we talk about what it is like to be a group of people with and without learning disabilities researching together. We describe the process of starting and maintaining the research group and reflect on the obstacles that we have come across, and the rewards such research has brought us. Lastly we put forward some ideas about the role…

  14. Mutated genes as research tool

    International Nuclear Information System (INIS)

    1981-01-01

    Green plants are the ultimate source of all resources required for man's life, his food, his clothes, and almost all his energy requirements. Primitive prehistoric man could live from the abundance of nature surrounding him. Man today, dominating nature in terms of numbers and exploiting its limited resources, cannot exist without employing his intelligence to direct natural evolution. Plant sciences, therefore, are not a matter of curiosity but an essential requirement. From such considerations, the IAEA and FAO jointly organized a symposium to assess the value of mutation research for various kinds of plant science, which directly or indirectly might contribute to sustaining and improving crop production. The benefit through developing better cultivars that plant breeders can derive from using the additional genetic resources resulting from mutation induction has been assessed before at other FAO/IAEA meetings (Rome 1964, Pullman 1969, Ban 1974, Ibadan 1978) and is also monitored in the Mutation Breeding Newsletter, published by IAEA twice a year. Several hundred plant cultivars which carry economically important characters because their genes have been altered by ionizing radiation or other mutagens, are grown by farmers and horticulturists in many parts of the world. But the benefit derived from such mutant varieties is without any doubt surpassed by the contribution which mutation research has made towards the advancement of genetics. For this reason, a major part of the papers and discussions at the symposium dealt with the role induced-mutation research played in providing insight into gene action and gene interaction, the organization of genes in plant chromosomes in view of homology and homoeology, the evolutionary role of gene duplication and polyploidy, the relevance of gene blocks, the possibilities for chromosome engineering, the functioning of cytroplasmic inheritance and the genetic dynamics of populations. In discussing the evolutionary role of

  15. Straightforward statistics understanding the tools of research

    CERN Document Server

    Geher, Glenn

    2014-01-01

    Straightforward Statistics: Understanding the Tools of Research is a clear and direct introduction to statistics for the social, behavioral, and life sciences. Based on the author's extensive experience teaching undergraduate statistics, this book provides a narrative presentation of the core principles that provide the foundation for modern-day statistics. With step-by-step guidance on the nuts and bolts of computing these statistics, the book includes detailed tutorials how to use state-of-the-art software, SPSS, to compute the basic statistics employed in modern academic and applied researc

  16. Blogging as a Research Tool

    Science.gov (United States)

    Sweetser, Douglas

    2011-11-01

    I work on variations of the Maxwell Lagrange density using quaternions and hypercomplex products of covariant 4-derivatives and 4-potentials. The hope is to unify gravity with the symmetries found in the standard model. It is difficult for someone outside academia to get constructive criticism. I have chosen to blog once a week at Science20.com since March, 2011. Over thirty blogs have been generated, most getting more than a thousand views (high mark is 5k for ``Why Quantum Mechanics is Wierd''). The tools used for web and video blogging will be reviewed. A discussion of my efforts to represent electroweak symmetry with quaternions convinced me I was in error. Instead, my hope is to exploit the observation that U(1) is formally a subgroup of SU(2). A battle over gauge symmetry may be reviewed.

  17. Drawing as a user experience research tool

    DEFF Research Database (Denmark)

    Fleury, Alexandre

    2011-01-01

    This paper discusses the use of participant-generated drawings as a user experience research method. In spite of the lack of background literature on how drawings can generate useful insights on HCI issues, drawings have been successfully used in other research fields. After briefly introducing...... research tool....

  18. A Monte Carlo tool for evaluating VMAT and DIMRT treatment deliveries including planar detectors

    International Nuclear Information System (INIS)

    Asuni, G; Van Beek, T A; Venkataraman, S; McCurdy, B M C; Popescu, I A

    2013-01-01

    The aim of this work is to describe and validate a new general research tool that performs Monte Carlo (MC) simulations for volumetric modulated arc therapy (VMAT) and dynamic intensity modulated radiation therapy (DIMRT), simultaneously tracking dose deposition in both the patient CT geometry and an arbitrary planar detector system. The tool is generalized to handle either entrance or exit detectors and provides the simulated dose for the individual control-points of the time-dependent VMAT and DIMRT deliveries. The MC simulation tool was developed with the EGSnrc radiation transport. For the individual control point simulation, we rotate the patient/phantom volume only (i.e. independent of the gantry and planar detector geometries) using the gantry angle in the treatment planning system (TPS) DICOM RP file such that each control point has its own unique phantom file. After MC simulation, we obtained the total dose to the phantom by summing dose contributions for all control points. Scored dose to the sensitive layer of the planar detector is available for each control point. To validate the tool, three clinical treatment plans were used including VMAT plans for a prostate case and a head-and-neck case, and a DIMRT plan for a head-and-neck case. An electronic portal imaging device operated in ‘movie’ mode was used with the VMAT plans delivered to cylindrical and anthropomorphic phantoms to validate the code using an exit detector. The DIMRT plan was delivered to a novel transmission detector, to validate the code using an entrance detector. The total MC 3D absolute doses in patient/phantom were compared with the TPS doses, while 2D MC doses were compared with planar detector doses for all individual control points, using the gamma evaluation test with 3%/3 mm criteria. The MC 3D absolute doses demonstrated excellent agreement with the TPS doses for all the tested plans, with about 95% of voxels having γ 90% of percentage pixels with γ <1. We found that over

  19. Interviewing Objects: Including Educational Technologies as Qualitative Research Participants

    Science.gov (United States)

    Adams, Catherine A.; Thompson, Terrie Lynn

    2011-01-01

    This article argues the importance of including significant technologies-in-use as key qualitative research participants when studying today's digitally enhanced learning environments. We gather a set of eight heuristics to assist qualitative researchers in "interviewing" technologies-in-use (or other relevant objects), drawing on concrete…

  20. Enabling Research Tools for Sustained Climate Assessment

    Science.gov (United States)

    Leidner, Allison K.; Bosilovich, Michael G.; Jasinski, Michael F.; Nemani, Ramakrishna R.; Waliser, Duane Edward; Lee, Tsengdar J.

    2016-01-01

    The U.S. Global Change Research Program Sustained Assessment process benefits from long-term investments in Earth science research that enable the scientific community to conduct assessment-relevant science. To this end, NASA initiated several research programs over the past five years to support the Earth observation community in developing indicators, datasets, research products, and tools to support ongoing and future National Climate Assessments. These activities complement NASA's ongoing Earth science research programs. One aspect of the assessment portfolio funds four "enabling tools" projects at NASA research centers. Each tool leverages existing capacity within the center, but has developed tailored applications and products for National Climate Assessments. The four projects build on the capabilities of a global atmospheric reanalysis (MERRA-2), a continental U.S. land surface reanalysis (NCA-LDAS), the NASA Earth Exchange (NEX), and a Regional Climate Model Evaluation System (RCMES). Here, we provide a brief overview of each enabling tool, highlighting the ways in which it has advanced assessment science to date. We also discuss how the assessment community can access and utilize these tools for National Climate Assessments and other sustained assessment activities.

  1. Researches regarding cutting tool condition monitoring

    Directory of Open Access Journals (Sweden)

    Inţă Marinela

    2017-01-01

    Full Text Available The paper main purpose is monitoring of tool wear in metal cutting using neural networks due to their ability of learning and adapting their self, based on experiments. Monitoring the cutting process is difficult to perform on-line because of the complexity of tool wear process, which is the most important parameter that defines the tool state at a certain moment. Most of the researches appraise the tool wear by indirect factors such as forces, consumed power, vibrations or the surface quality. In this case, it is important to combine many factors for increasing the accuracy of tool wear prediction and establish the admissible size of wear. For this, paper both the theoretical data obtained from FEM analyze and experimental ones are used and compared in order to appreciate the reliability of the results.

  2. Bioinformatics Tools for Extracellular Vesicles Research.

    Science.gov (United States)

    Keerthikumar, Shivakumar; Gangoda, Lahiru; Gho, Yong Song; Mathivanan, Suresh

    2017-01-01

    Extracellular vesicles (EVs) are a class of membranous vesicles that are released by multiple cell types into the extracellular environment. This unique class of extracellular organelles which play pivotal role in intercellular communication are conserved across prokaryotes and eukaryotes. Depending upon the cell origin and the functional state, the molecular cargo including proteins, lipids, and RNA within the EVs are modulated. Owing to this, EVs are considered as a subrepertoire of the host cell and are rich reservoirs of disease biomarkers. In addition, the availability of EVs in multiple bodily fluids including blood has created significant interest in biomarker and signaling research. With the advancement in high-throughput techniques, multiple EV studies have embarked on profiling the molecular cargo. To benefit the scientific community, existing free Web-based resources including ExoCarta, EVpedia, and Vesiclepedia catalog multiple datasets. These resources aid in elucidating molecular mechanism and pathophysiology underlying different disease conditions from which EVs are isolated. Here, the existing bioinformatics tools to perform integrated analysis to identify key functional components in the EV datasets are discussed.

  3. Telerehabilitation: Policy Issues and Research Tools

    Directory of Open Access Journals (Sweden)

    Katherine D. Seelman

    2009-09-01

    Full Text Available The importance of public policy as a complementary framework for telehealth, telemedicine, and by association telerehabilitation, has been recognized by a number of experts. The purpose of this paper is to review literature on telerehabilitation (TR policy and research methodology issues in order to report on the current state of the science and make recommendations about future research needs. An extensive literature search was implemented using search terms grouped into main topics of telerehabilitation, policy, population of users, and policy specific issues such as cost and reimbursement. The availability of rigorous and valid evidence-based cost studies emerged as a major challenge to the field. Existing cost studies provided evidence that telehomecare may be a promising application area for TR. Cost studies also indicated that telepsychiatry is a promising telepractice area. The literature did not reference the International Classification on Functioning, Disability and Health (ICF. Rigorous and comprehensive TR assessment and evaluation tools for outcome studies are tantamount to generating confidence among providers, payers, clinicians and end users. In order to evaluate consumer satisfaction and participation, assessment criteria must include medical, functional and quality of life items such as assistive technology and environmental factors. Keywords: Telerehabilitation, Telehomecare, Telepsychiatry, Telepractice

  4. Applied regression analysis a research tool

    CERN Document Server

    Pantula, Sastry; Dickey, David

    1998-01-01

    Least squares estimation, when used appropriately, is a powerful research tool. A deeper understanding of the regression concepts is essential for achieving optimal benefits from a least squares analysis. This book builds on the fundamentals of statistical methods and provides appropriate concepts that will allow a scientist to use least squares as an effective research tool. Applied Regression Analysis is aimed at the scientist who wishes to gain a working knowledge of regression analysis. The basic purpose of this book is to develop an understanding of least squares and related statistical methods without becoming excessively mathematical. It is the outgrowth of more than 30 years of consulting experience with scientists and many years of teaching an applied regression course to graduate students. Applied Regression Analysis serves as an excellent text for a service course on regression for non-statisticians and as a reference for researchers. It also provides a bridge between a two-semester introduction to...

  5. The Pometum Apple Key - an internet tool for genebank data including cultivar identification

    DEFF Research Database (Denmark)

    Toldam-Andersen, Torben; Korsgaard, Maren; Nordling, Jonas

    2011-01-01

    of apples from 22 countries is maintained. Most are historic local cultivars from Denmark and the neighboring countries. We experience large public interest in information about the collection. To communicate the information collected over the years we initiated a visually simplified internet platform...... and communicating the information to breeders, researchers and especially the public the challenge appears to be almost impossible. If one visits a range of genebank homepages around the world it is very difficult to extract the information even for specialists. At The Pometum a collection of around 800 cultivars....... A dual aim was; firstly to present the diversity of apples in terms of appearance and qualities and also allow the inclusion of unique historical and cultural information including photos, pomological drawings and paintings. Secondly, the aim was to develop a tool for identification of cultivars and easy...

  6. Ecomapping: an innovative research tool for nurses.

    Science.gov (United States)

    Ray, Robin A; Street, Annette F

    2005-06-01

    This paper explores the use of ecomaps as a research tool for capturing data, using the example of the dynamic nature of social networks from which informal carers of people living with motor neurone disease draw their support. The need for social support in relation to health maintenance and disease management has been identified in the literature but little has been published about ways to investigate support networks. Existing discussion in the literature about the use of ecomaps as a clinical tool in social work creates a valuable framework for data collection which can be readily adapted by nurse researchers. We used ecomaps as part of a repertoire of research tools to gather data about the social networks of carers of people living with motor neurone disease. Primary carers participated in three interviews and collaborated in ecomap construction over a period of 10 months during 2003. Analytical correlations were made between ecomaps and interview data. Ecomaps provided a visual means of facilitating discussions around the structure and strength of networks. Being able to represent the social networks visually through ecomapping enabled people to identify each member of the network, examine the strength of each relationship and ascertain the sources of nurture and tension over time. Limitations to this type of data collection arise when participants try to quantify relationships that have been visually produced. Ecomapping is a valuable research tool because it provides visual representation of supportive care networks, capturing strategic data through symbols expressing relationships that may be inadequately portrayed in words. The ecomap incorporates the use of consistent symbols that standardize recipient responses, enabling data comparisons to be made.

  7. Repeatability of food frequency assessment tools in relation to the number of items and response categories included.

    Science.gov (United States)

    Bountziouka, Vassiliki; Bathrellou, Eirini; Zazpe, Itziar; Ezquer, Leyre; Martínez-González, Miguel-Angel; Panagiotakos, Demosthenes B

    2012-12-01

    Accuracy of measurement is a cornerstone of research in order to make robust conclusions about the research hypothesis. To examine whether the number of items (questions) and the number of consumption responses (the coding used to measure the frequency of consumption) included in nutritional assessment tools influence their repeatability. During 2009, 400 participants (250 from Greece, mean age 37 +/- 13 years, 34% males, and 150 from Spain, mean age 39 +/- 17 years, 41% males) completed a diet index with 11 items and binary (yes/ no) responses, a diet index with 11 items and 6-scale responses, and 36-item and 76-item food frequency questionnaires (FFQs) with 6-scale responses. The participants completed these tools twice, with 15 days between the two administrations of the tools. The Spearman-Brown coefficient (r(sb)), Kendall's tau coefficients, and the Bland-Altman method were applied to answer the research hypothesis. The highest repeatability coefficient was observed for the diet index with 11 items and binary (yes/no) responses (r(sb) = 0.948, p tools (p > .23), whereas these three tools had significantly higher repeatability coefficients than the 76-item FFQ (p = .002). Subgroup analyses by sex, education, smoking, and clinical status confirmed these results. Repeatability was found for all food frequency assessment tools used, irrespective of the number of items or the number of responses included.

  8. FOSS Tools for Research Data Management

    Science.gov (United States)

    Stender, Vivien; Jankowski, Cedric; Hammitzsch, Martin; Wächter, Joachim

    2017-04-01

    Established initiatives and organizations, e.g. the Initiative for Scientific Cyberinfrastructures (NSF, 2007) or the European Strategy Forum on Research Infrastructures (ESFRI, 2008), promote and foster the development of sustainable research infrastructures. These infrastructures aim the provision of services supporting scientists to search, visualize and access data, to collaborate and exchange information, as well as to publish data and other results. In this regard, Research Data Management (RDM) gains importance and thus requires the support by appropriate tools integrated in these infrastructures. Different projects provide arbitrary solutions to manage research data. However, within two projects - SUMARIO for land and water management and TERENO for environmental monitoring - solutions to manage research data have been developed based on Free and Open Source Software (FOSS) components. The resulting framework provides essential components for harvesting, storing and documenting research data, as well as for discovering, visualizing and downloading these data on the basis of standardized services stimulated considerably by enhanced data management approaches of Spatial Data Infrastructures (SDI). In order to fully exploit the potentials of these developments for enhancing data management in Geosciences the publication of software components, e.g. via GitHub, is not sufficient. We will use our experience to move these solutions into the cloud e.g. as PaaS or SaaS offerings. Our contribution will present data management solutions for the Geosciences developed in two projects. A sort of construction kit with FOSS components build the backbone for the assembly and implementation of projects specific platforms. Furthermore, an approach is presented to stimulate the reuse of FOSS RDM solutions with cloud concepts. In further projects specific RDM platforms can be set-up much faster, customized to the individual needs and tools can be added during the run-time.

  9. Repeatability of food frequency assessment tools in relation to the number of items and response categories included

    OpenAIRE

    Bountziouka, V. (Vassiliki); Bathrellou, E. (Eirini); Zazpe, I. (Itziar); Ezquer, L. (Leyre); Martinez-Gonzalez, M.A. (Miguel Ángel); Panagiotakos, D.B. (Demosthenes B.)

    2012-01-01

    Background: Accuracy of a measurement is a cornerstone in research in order to make robust conclusions about the research hypothesis. Objective: To examine whether the number of items (questions) and the number of responses of consumption included in nutritional assessment tools influence their repeatability. Methods: During 2009, 400 participants (250 from Greece, 37±13 yrs, 34% males and 150 participants from Spain, 39±17 yrs, 41% males) completed a diet index with 11-items a...

  10. Spec Tool; an online education and research resource

    Directory of Open Access Journals (Sweden)

    S. Maman

    2016-06-01

    Full Text Available Education and public outreach (EPO activities related to remote sensing, space, planetary and geo-physics sciences have been developed widely in the Earth and Planetary Image Facility (EPIF at Ben-Gurion University of the Negev, Israel. These programs aim to motivate the learning of geo-scientific and technologic disciplines. For over the past decade, the facility hosts research and outreach activities for researchers, local community, school pupils, students and educators. As software and data are neither available nor affordable, the EPIF Spec tool was created as a web-based resource to assist in initial spectral analysis as a need for researchers and students. The tool is used both in the academic courses and in the outreach education programs and enables a better understanding of the theoretical data of spectroscopy and Imaging Spectroscopy in a 'hands-on' activity. This tool is available online and provides spectra visualization tools and basic analysis algorithms including Spectral plotting, Spectral angle mapping and Linear Unmixing. The tool enables to visualize spectral signatures from the USGS spectral library and additional spectra collected in the EPIF such as of dunes in southern Israel and from Turkmenistan. For researchers and educators, the tool allows loading collected samples locally for further analysis.

  11. ARCHER – e-Research Tools for Research Data Management

    Directory of Open Access Journals (Sweden)

    Steve Androulakis

    2009-06-01

    Full Text Available Normal 0 With new scientific instruments growing exponentially in their capability to generate research data, new infrastructure needs to be developed and deployed to allow researchers to effectively and securely manage their research data from collection, publication, and eventual dissemination to research communities.  In particular, researchers need to be able to easily acquire data from instruments, store and manage potentially large quantities of data, easily process the data, share research resources and work spaces with colleagues both inside and outside of their institution, search and discover across their accessible collections, and easily publish datasets and related research artefacts.  The ARCHER Project has developed production-ready generic e-Research infrastructure including: a Research Repository; Scientific Dataset Managers (both a web and desktop application; Distributed Integrated Multi-Sensor and Instrument Middleware; and a Collaborative Workspace Environment.  Institutions can selectively deploy these components to greatly assist their researchers in managing their research data.

  12. Why include phenomenological analysis in a Research Methods course?

    Science.gov (United States)

    Delgado, Ana R

    2013-01-01

    Guidelines for Spanish university curricula include the descriptor Quantitative and Qualitative Methods, but the latter are still poorly represented. To inform the argument for phenomenological methods, the last 20-year interval of ISI databases has been content-analyzed with the following codes: discourse analysis, grounded theory, narrative analysis, phenomenological analysis and confirmatory factor analysis, that is, four qualitative methods and a prototypical quantitative one. In absolute terms, the most frequent qualitative method is grounded theory, followed by discourse analysis, phenomenological analysis and narrative analysis. However, taking into account content categories, only phenomenological analysis shows a clear psychological profile, similar to confirmatory factor analysis. We recommend starting qualitative training with a method that does not require either big groups, or big funding, and that has a procedural core that is simple, relatively well-delimited and "secularizable," a variety of thematic analysis. Historical reasons and the clear psychological profile evidenced by our results enhance our argument to foster the inclusion of phenomenological analysis in research method courses in psychology.

  13. Basic Research Tools for Earthworm Ecology

    Directory of Open Access Journals (Sweden)

    Kevin R. Butt

    2010-01-01

    Full Text Available Earthworms are responsible for soil development, recycling organic matter and form a vital component within many food webs. For these and other reasons earthworms are worthy of investigation. Many technologically-enhanced approaches have been used within earthworm-focused research. These have their place, may be a development of existing practices or bring techniques from other fields. Nevertheless, let us not overlook the fact that much can still be learned through utilisation of more basic approaches which have been used for some time. New does not always equate to better. Information on community composition within an area and specific population densities can be learned using simple collection techniques, and burrowing behaviour can be determined from pits, resin-insertion or simple mesocosms. Life history studies can be achieved through maintenance of relatively simple cultures. Behavioural observations can be undertaken by direct observation or with low cost webcam usage. Applied aspects of earthworm research can also be achieved through use of simple techniques to enhance population development and even population dynamics can be directly addressed with use of relatively inexpensive, effective marking techniques. This paper seeks to demonstrate that good quality research in this sphere can result from appropriate application of relatively simple research tools.

  14. Basic Research Tools for Earthworm Ecology

    International Nuclear Information System (INIS)

    Butt, K.R.; Grigoropoulou, N.

    2010-01-01

    Earthworms are responsible for soil development, recycling organic matter and form a vital component within many food webs. For these and other reasons earthworms are worthy of investigation. Many technologically-enhanced approaches have been used within earthworm-focused research. These have their place, may be a development of existing practices or bring techniques from other fields. Nevertheless, let us not overlook the fact that much can still be learned through utilisation of more basic approaches which have been used for some time. New does not always equate to better. Information on community composition within an area and specific population densities can be learned using simple collection techniques, and burrowing behaviour can be determined from pits, resin-insertion or simple mesocosms. Life history studies can be achieved through maintenance of relatively simple cultures. Behavioural observations can be undertaken by direct observation or with low cost we became usage. Applied aspects of earthworm research can also be achieved through use of simple techniques to enhance population development and even population dynamics can be directly addressed with use of relatively inexpensive, effective marking techniques. This paper seeks to demonstrate that good quality research in this sphere can result from appropriate application of relatively simple research tools.

  15. The CATS Service: An Astrophysical Research Tool

    Directory of Open Access Journals (Sweden)

    O V Verkhodanov

    2009-03-01

    Full Text Available We describe the current status of CATS (astrophysical CATalogs Support system, a publicly accessible tool maintained at Special Astrophysical Observatory of the Russian Academy of Sciences (SAO RAS (http://cats.sao.ru allowing one to search hundreds of catalogs of astronomical objects discovered all along the electromagnetic spectrum. Our emphasis is mainly on catalogs of radio continuum sources observed from 10 MHz to 245 GHz, and secondly on catalogs of objects such as radio and active stars, X-ray binaries, planetary nebulae, HII regions, supernova remnants, pulsars, nearby and radio galaxies, AGN and quasars. CATS also includes the catalogs from the largest extragalactic surveys with non-radio waves. In 2008 CATS comprised a total of about 109 records from over 400 catalogs in the radio, IR, optical and X-ray windows, including most source catalogs deriving from observations with the Russian radio telescope RATAN-600. CATS offers several search tools through different ways of access, e.g. via Web-interface and e-mail. Since its creation in 1997 CATS has managed about 105requests. Currently CATS is used by external users about 1500 times per day and since its opening to the public in 1997 has received about 4000 requests for its selection and matching tasks.

  16. Methodological challenges when doing research that includes ethnic minorities

    DEFF Research Database (Denmark)

    Morville, Anne-Le; Erlandsson, Lena-Karin

    2016-01-01

    Background: There are challenging methodological issues in obtaining valid and reliable results on which to base occupational therapy interventions for ethnic minorities. The aim of this scoping review is to describe the methodological problems within occupational therapy research, when ethnic...... research and interventions, development of methods for the entire research process is needed. It is a costly and time-consuming process, but the results will be valid and reliable, and therefore more applicable in clinical practice...

  17. Scalable Combinatorial Tools for Health Disparities Research

    Directory of Open Access Journals (Sweden)

    Michael A. Langston

    2014-10-01

    Full Text Available Despite staggering investments made in unraveling the human genome, current estimates suggest that as much as 90% of the variance in cancer and chronic diseases can be attributed to factors outside an individual’s genetic endowment, particularly to environmental exposures experienced across his or her life course. New analytical approaches are clearly required as investigators turn to complicated systems theory and ecological, place-based and life-history perspectives in order to understand more clearly the relationships between social determinants, environmental exposures and health disparities. While traditional data analysis techniques remain foundational to health disparities research, they are easily overwhelmed by the ever-increasing size and heterogeneity of available data needed to illuminate latent gene x environment interactions. This has prompted the adaptation and application of scalable combinatorial methods, many from genome science research, to the study of population health. Most of these powerful tools are algorithmically sophisticated, highly automated and mathematically abstract. Their utility motivates the main theme of this paper, which is to describe real applications of innovative transdisciplinary models and analyses in an effort to help move the research community closer toward identifying the causal mechanisms and associated environmental contexts underlying health disparities. The public health exposome is used as a contemporary focus for addressing the complex nature of this subject.

  18. Meson facility. Powerful new research tool

    International Nuclear Information System (INIS)

    Lobashev, V.M.; Tavkhelidze, A.N.

    A meson facility is being built at the Institute of Nuclear Research, USSR Academy of Sciences, in Troitsk, where the Scientific Center, USSR Academy of Sciences is located. The facility will include a linear accelerator for protons and negative hydrogen ions with 600 MeV energy and 0.5-1 mA beam current. Some fundamental studies that can be studied at a meson facility are described in the areas of elementary particles, neutron physics, solid state physics, and applied research. The characteristics of the linear accelerator are given and the meson facility's experimental complex is described

  19. Canine cancer patients are included in translational research

    DEFF Research Database (Denmark)

    Børresen, Betina; Clausen, Malene Martini; Hansen, Anders Elias

    2014-01-01

    Cancer bearing dogs represent a unique clinical cancer model with a direct potential for accelerating translation into human patients. A research collaboration between the veterinary and human medical facilities at Copenhagen University and Rigshospitalet has taken offset in this. Canine cancer...

  20. Including People with Intellectual Disabilities in Qualitative Research

    Science.gov (United States)

    Hall, Sarah A.

    2013-01-01

    The voice of people with intellectual disabilities (ID) is needed in the literature to best understand their unique experiences and perspectives. Researchers face challenges in conducting interviews with people with ID who are limited in conceptual and verbal language skills. It can also be difficult to obtain participants with ID because of…

  1. Integrating information technologies as tools for surgical research.

    Science.gov (United States)

    Schell, Scott R

    2005-10-01

    Surgical research is dependent upon information technologies. Selection of the computer, operating system, and software tool that best support the surgical investigator's needs requires careful planning before research commences. This manuscript presents a brief tutorial on how surgical investigators can best select these information technologies, with comparisons and recommendations between existing systems, software, and solutions. Privacy concerns, based upon HIPAA and other regulations, now require careful proactive attention to avoid legal penalties, civil litigation, and financial loss. Security issues are included as part of the discussions related to selection and application of information technology. This material was derived from a segment of the Association for Academic Surgery's Fundamentals of Surgical Research course.

  2. VAO Tools Enhance CANDELS Research Productivity

    Science.gov (United States)

    Greene, Gretchen; Donley, J.; Rodney, S.; LAZIO, J.; Koekemoer, A. M.; Busko, I.; Hanisch, R. J.; VAO Team; CANDELS Team

    2013-01-01

    The formation of galaxies and their co-evolution with black holes through cosmic time are prominent areas in current extragalactic astronomy. New methods in science research are building upon collaborations between scientists and archive data centers which span large volumes of multi-wavelength and heterogeneous data. A successful example of this form of teamwork is demonstrated by the CANDELS (Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey) and the Virtual Astronomical Observatory (VAO) collaboration. The CANDELS project archive data provider services are registered and discoverable in the VAO through an innovative web based Data Discovery Tool, providing a drill down capability and cross-referencing with other co-spatially located astronomical catalogs, images and spectra. The CANDELS team is working together with the VAO to define new methods for analyzing Spectral Energy Distributions of galaxies containing active galactic nuclei, and helping to evolve advanced catalog matching methods for exploring images of variable depths, wavelengths and resolution. Through the publication of VOEvents, the CANDELS project is publishing data streams for newly discovered supernovae that are bright enough to be followed from the ground.

  3. Evaluating Research Impact: The Development of a Research for Impact Tool.

    Science.gov (United States)

    Tsey, Komla; Lawson, Kenny; Kinchin, Irina; Bainbridge, Roxanne; McCalman, Janya; Watkin, Felecia; Cadet-James, Yvonne; Rossetto, Allison

    2016-01-01

    context of Aboriginal and Torres Strait Islander research but the basic idea that the way to assess research impact is to start upfront with the information needs of decisions makers is equally applicable to research in other settings, both applied (horizontal) and basic (vertical) research. The tool will be further tested and evaluated with researchers over the next 2 years (2016/17). The decision by the Australian Government to include 'industry engagement' and 'impact' as additions to the Excellence in Research for Australia (ERA) quality measures from 2018 makes the Research for Impact Tool a timely development. The wider challenge is to engage with major Australian research funding agencies to ensure consistent alignment and approaches across research users, communities, and funders in evaluating impact.

  4. GSI research and development programme 1992 (including programme budget)

    International Nuclear Information System (INIS)

    1992-01-01

    The main points on UNILAC will be preparatory experiments on the synthesis of the element 110 and the study of e + e 1 - pair generation for heavy ion impacts on the Coulomb barrier. Experiments on beam fragmentation, to generate and apply radioactive beams and for producing mesons and antiprotons below the threshold will be to the fore at SIS. The central detector of the 4 π detector for exclusive particle production studies will also be set to work. Up to now, the electron cooling and storage experiments have shown, in the main, how heavy ion beams such as 20 Ne, 40 Ar, 86 Kr, 136 Xe and 209 Bi are stored and can be cooled with electron beams to the highest phase space densities (Δ p/p ≅ 10 -6 , ε ≅ 0.3 π mm x mrad). The cooling experiments will be continued, particularly in order to research the conditions for beam condensation. In a series of experiments, electron-ion and laser-ion interaction processes such as radiation capture, dielectric recombination and laser-induced transitions are examined. Spectroscopy experiments on hydrogen- and helium-like heavy atoms to examined QED effects are being started. (orig.) [de

  5. Some tooling for manufacturing research reactor fuel plates

    International Nuclear Information System (INIS)

    Knight, R.W.

    1999-01-01

    This paper will discuss some of the tooling necessary to manufacture aluminum-based research reactor fuel plates. Most of this tooling is intended for use in a high-production facility. Some of the tools shown have manufactured more than 150,000 pieces. The only maintenance has been sharpening. With careful design, tools can be made to accommodate the manufacture of several different fuel elements, thus, reducing tooling costs and maintaining tools that the operators are trained to use. An important feature is to design the tools using materials with good lasting quality. Good tools can increase return on investment. (author)

  6. Some Tooling for Manufacturing Research Reactor Fuel Plates

    International Nuclear Information System (INIS)

    Knight, R.W.

    1999-01-01

    This paper will discuss some of the tooling necessary to manufacture aluminum-based research reactor fuel plates. Most of this tooling is intended for use in a high-production facility. Some of the tools shown have manufactured more than 150,000 pieces. The only maintenance has been sharpening. With careful design, tools can be made to accommodate the manufacture of several different fuel elements, thus, reducing tooling costs and maintaining tools that the operators are trained to use. An important feature is to design the tools using materials with good lasting quality. Good tools can increase return on investment

  7. HEPS Inventory Tool: An Inventory Tool Including Quality Assessment of School Interventions on Healthy Eating and Physical Activity

    Science.gov (United States)

    Dadaczynski, Kevin; Paulus, Peter; de Vries, Nanne; de Ruiter, Silvia; Buijs, Goof

    2010-01-01

    The HEPS Inventory Tool aims to support stakeholders working in school health promotion to promote high quality interventions on healthy eating and physical activity. As a tool it provides a step-by-step approach on how to develop a national or regional inventory of existing school based interventions on healthy eating and physical activity. It…

  8. Forum Theater’s potential as a Research Tool

    Directory of Open Access Journals (Sweden)

    Andrea Calsamiglia Madurga

    2016-03-01

    Full Text Available We present a theoretical and epistemological reflection on Forum Theater’s potential as a Research Tool. Our presence on social action and research has led us to a double reflection on qualitative research’s limitations on the affect studies and the Forum Theater’s potential as a research tool to tackle research about affects. After some specific experiences in action research (qualitative research on romantic love and gender violence, and the creation process of the Forum Theater “Is it a joke?”, we explore Forum Theatre’s possibilities as a research tool in the feminist epistemology framework.

  9. Market research companies and new product development tools

    NARCIS (Netherlands)

    Nijssen, Edwin J.; Frambach, Ruud T.

    1998-01-01

    This research investigates (1) the share of new product development (NPD) research services in market research (MR) companies' turnover, (2) MR companies' awareness and use of NPD tools and the modifications made to these NPD tools, and (3) MR company managers' perceptions of the influence of client

  10. Market research companies and new product development tools

    NARCIS (Netherlands)

    Nijssen, E.J.; Frambach, R.T.

    1998-01-01

    This research investigates (1) the share of new product development (NPD) research services in market research (MR) companies’ turnover, (2) MR companies’ awareness and use of NPD tools and the modifications made to these NPD tools, and (3) MR company managers’ perceptions of the influence of client

  11. Simulation tool for optical design of PET detector modules including scintillator material and sensor array

    Energy Technology Data Exchange (ETDEWEB)

    Jatekos, B.; Erdei, G.; Lorincz, E. [Budapest Univ. of Technology and Economics, Dept. of Atomic Physics, Budafoki ut 8, H-1111 Budapest (Hungary)

    2011-07-01

    The appearance of single photon avalanche diodes (SPADs) in the field of PET detector modules made it necessary to apply more complex optical design methods to refine the performance of such assemblies. We developed a combined simulation tool that is capable to model complex detector structures including scintillation material, light guide, light collection optics and sensor, correctly taking into account the statistical behavior of emission of scintillation light and its absorbance in SPADs. As a validation we compared simulation results obtained by our software and another optical design program. Calculations were performed for a simple PET detector arrangement used for testing purposes. According to the results, deviation of center of gravity coordinates between the two simulations is 0.0195 mm, the average ratio of total counts 1.0052. We investigated the error resulting from finite sampling in wavelength space and we found that 20 nm pitch is sufficient for the simulation in case of the given spectral dependencies. (authors)

  12. ARM Climate Research Facility: Outreach Tools and Strategies

    Science.gov (United States)

    Roeder, L.; Jundt, R.

    2009-12-01

    Sponsored by the Department of Energy, the ARM Climate Research Facility is a global scientific user facility for the study of climate change. To publicize progress and achievements and to reach new users, the ACRF uses a variety of Web 2.0 tools and strategies that build off of the program’s comprehensive and well established News Center (www.arm.gov/news). These strategies include: an RSS subscription service for specific news categories; an email “newsletter” distribution to the user community that compiles the latest News Center updates into a short summary with links; and a Facebook page that pulls information from the News Center and links to relevant information in other online venues, including those of our collaborators. The ACRF also interacts with users through field campaign blogs, like Discovery Channel’s EarthLive, to share research experiences from the field. Increasingly, field campaign Wikis are established to help ACRF researchers collaborate during the planning and implementation phases of their field studies and include easy to use logs and image libraries to help record the campaigns. This vital reference information is used in developing outreach material that is shared in highlights, news, and Facebook. Other Web 2.0 tools that ACRF uses include Google Maps to help users visualize facility locations and aircraft flight patterns. Easy-to-use comment boxes are also available on many of the data-related web pages on www.arm.gov to encourage feedback. To provide additional opportunities for increased interaction with the public and user community, future Web 2.0 plans under consideration for ACRF include: evaluating field campaigns for Twitter and microblogging opportunities, adding public discussion forums to research highlight web pages, moving existing photos into albums on FlickR or Facebook, and building online video archives through YouTube.

  13. Genephony: a knowledge management tool for genome-wide research

    Directory of Open Access Journals (Sweden)

    Riva Alberto

    2009-09-01

    Full Text Available Abstract Background One of the consequences of the rapid and widespread adoption of high-throughput experimental technologies is an exponential increase of the amount of data produced by genome-wide experiments. Researchers increasingly need to handle very large volumes of heterogeneous data, including both the data generated by their own experiments and the data retrieved from publicly available repositories of genomic knowledge. Integration, exploration, manipulation and interpretation of data and information therefore need to become as automated as possible, since their scale and breadth are, in general, beyond the limits of what individual researchers and the basic data management tools in normal use can handle. This paper describes Genephony, a tool we are developing to address these challenges. Results We describe how Genephony can be used to manage large datesets of genomic information, integrating them with existing knowledge repositories. We illustrate its functionalities with an example of a complex annotation task, in which a set of SNPs coming from a genotyping experiment is annotated with genes known to be associated to a phenotype of interest. We show how, thanks to the modular architecture of Genephony and its user-friendly interface, this task can be performed in a few simple steps. Conclusion Genephony is an online tool for the manipulation of large datasets of genomic information. It can be used as a browser for genomic data, as a high-throughput annotation tool, and as a knowledge discovery tool. It is designed to be easy to use, flexible and extensible. Its knowledge management engine provides fine-grained control over individual data elements, as well as efficient operations on large datasets.

  14. Primer on consumer marketing research : procedures, methods, and tools

    Science.gov (United States)

    1994-03-01

    The Volpe Center developed a marketing research primer which provides a guide to the approach, procedures, and research tools used by private industry in predicting consumer response. The final two chapters of the primer focus on the challenges of do...

  15. Data Integration Tool: From Permafrost Data Translation Research Tool to A Robust Research Application

    Science.gov (United States)

    Wilcox, H.; Schaefer, K. M.; Jafarov, E. E.; Strawhacker, C.; Pulsifer, P. L.; Thurmes, N.

    2016-12-01

    The United States National Science Foundation funded PermaData project led by the National Snow and Ice Data Center (NSIDC) with a team from the Global Terrestrial Network for Permafrost (GTN-P) aimed to improve permafrost data access and discovery. We developed a Data Integration Tool (DIT) to significantly speed up the time of manual processing needed to translate inconsistent, scattered historical permafrost data into files ready to ingest directly into the GTN-P. We leverage this data to support science research and policy decisions. DIT is a workflow manager that divides data preparation and analysis into a series of steps or operations called widgets. Each widget does a specific operation, such as read, multiply by a constant, sort, plot, and write data. DIT allows the user to select and order the widgets as desired to meet their specific needs. Originally it was written to capture a scientist's personal, iterative, data manipulation and quality control process of visually and programmatically iterating through inconsistent input data, examining it to find problems, adding operations to address the problems, and rerunning until the data could be translated into the GTN-P standard format. Iterative development of this tool led to a Fortran/Python hybrid then, with consideration of users, licensing, version control, packaging, and workflow, to a publically available, robust, usable application. Transitioning to Python allowed the use of open source frameworks for the workflow core and integration with a javascript graphical workflow interface. DIT is targeted to automatically handle 90% of the data processing for field scientists, modelers, and non-discipline scientists. It is available as an open source tool in GitHub packaged for a subset of Mac, Windows, and UNIX systems as a desktop application with a graphical workflow manager. DIT was used to completely translate one dataset (133 sites) that was successfully added to GTN-P, nearly translate three datasets

  16. A tool to include gamma analysis software into a quality assurance program.

    Science.gov (United States)

    Agnew, Christina E; McGarry, Conor K

    2016-03-01

    To provide a tool to enable gamma analysis software algorithms to be included in a quality assurance (QA) program. Four image sets were created comprising two geometric images to independently test the distance to agreement (DTA) and dose difference (DD) elements of the gamma algorithm, a clinical step and shoot IMRT field and a clinical VMAT arc. The images were analysed using global and local gamma analysis with 2 in-house and 8 commercially available software encompassing 15 software versions. The effect of image resolution on gamma pass rates was also investigated. All but one software accurately calculated the gamma passing rate for the geometric images. Variation in global gamma passing rates of 1% at 3%/3mm and over 2% at 1%/1mm was measured between software and software versions with analysis of appropriately sampled images. This study provides a suite of test images and the gamma pass rates achieved for a selection of commercially available software. This image suite will enable validation of gamma analysis software within a QA program and provide a frame of reference by which to compare results reported in the literature from various manufacturers and software versions. Copyright © 2015. Published by Elsevier Ireland Ltd.

  17. Drawing as a user experience research tool

    DEFF Research Database (Denmark)

    Fleury, Alexandre

    2011-01-01

    This paper discusses the use of participant-generated drawings as a user experience research method. In spite of the lack of background literature on how drawings can generate useful insights on HCI issues, drawings have been successfully used in other research fields. After briefly introducing...... such previous work, two case studies are presented, in which drawings helped investigate the relationship between media technology users and two specific devices, namely television and mobile phones. The experiment generated useful data and opened for further consideration of the method as an appropriate HCI...

  18. LITERATURE REVIEWING WITH RESEARCH TOOLS, Part 1: Systematic Review

    OpenAIRE

    Ebrahim, Nader Ale

    2017-01-01

    Research Tools” enable researchers to collect, organize, analyze, visualize and publicized research outputs. Dr. Nader has collected over 700 tools that enable students to follow the correct path in research and to ultimately produce high-quality research outputs with more accuracy and efficiency. It is assembled as an interactive Web-based mind map, titled “Research Tools”, which is updated periodically. “Research Tools” consists of a hierarchical set of nodes. It has four main nodes: (1)...

  19. LITERATURE REVIEWING WITH RESEARCH TOOLS, Part 3: Writing Literature Review

    OpenAIRE

    Ebrahim, Nader Ale

    2017-01-01

    Research Tools” enable researchers to collect, organize, analyze, visualize and publicized research outputs. Dr. Nader has collected over 700 tools that enable students to follow the correct path in research and to ultimately produce high-quality research outputs with more accuracy and efficiency. It is assembled as an interactive Web-based mind map, titled “Research Tools”, which is updated periodically. “Research Tools” consists of a hierarchical set of nodes. It has four main nodes: (1)...

  20. Equity Audit: A Teacher Leadership Tool for Nurturing Teacher Research

    Science.gov (United States)

    View, Jenice L.; DeMulder, Elizabeth; Stribling, Stacia; Dodman, Stephanie; Ra, Sophia; Hall, Beth; Swalwell, Katy

    2016-01-01

    This is a three-part essay featuring six teacher educators and one classroom teacher researcher. Part one describes faculty efforts to build curriculum for teacher research, scaffold the research process, and analyze outcomes. Part two shares one teacher researcher's experience using an equity audit tool in several contexts: her teaching practice,…

  1. Simulation tools for robotics research and assessment

    Science.gov (United States)

    Fields, MaryAnne; Brewer, Ralph; Edge, Harris L.; Pusey, Jason L.; Weller, Ed; Patel, Dilip G.; DiBerardino, Charles A.

    2016-05-01

    The Robotics Collaborative Technology Alliance (RCTA) program focuses on four overlapping technology areas: Perception, Intelligence, Human-Robot Interaction (HRI), and Dexterous Manipulation and Unique Mobility (DMUM). In addition, the RCTA program has a requirement to assess progress of this research in standalone as well as integrated form. Since the research is evolving and the robotic platforms with unique mobility and dexterous manipulation are in the early development stage and very expensive, an alternate approach is needed for efficient assessment. Simulation of robotic systems, platforms, sensors, and algorithms, is an attractive alternative to expensive field-based testing. Simulation can provide insight during development and debugging unavailable by many other means. This paper explores the maturity of robotic simulation systems for applications to real-world problems in robotic systems research. Open source (such as Gazebo and Moby), commercial (Simulink, Actin, LMS), government (ANVEL/VANE), and the RCTA-developed RIVET simulation environments are examined with respect to their application in the robotic research domains of Perception, Intelligence, HRI, and DMUM. Tradeoffs for applications to representative problems from each domain are presented, along with known deficiencies and disadvantages. In particular, no single robotic simulation environment adequately covers the needs of the robotic researcher in all of the domains. Simulation for DMUM poses unique constraints on the development of physics-based computational models of the robot, the environment and objects within the environment, and the interactions between them. Most current robot simulations focus on quasi-static systems, but dynamic robotic motion places an increased emphasis on the accuracy of the computational models. In order to understand the interaction of dynamic multi-body systems, such as limbed robots, with the environment, it may be necessary to build component

  2. Including values in evidence-based policy making for breast screening: An empirically grounded tool to assist expert decision makers.

    Science.gov (United States)

    Parker, Lisa

    2017-07-01

    Values are an important part of evidence-based decision making for health policy: they guide the type of evidence that is collected, how it is interpreted, and how important the conclusions are considered to be. Experts in breast screening (including clinicians, researchers, consumer advocates and senior administrators) hold differing values in relation to what is important in breast screening policy and practice, and committees may find it difficult to incorporate the complexity and variety of values into policy decisions. The decision making tool provided here is intended to assist with this process. The tool is modified from more general frameworks that are intended to assist with ethical decision making in public health, and informed by data drawn from previous empirical studies on values amongst Australian breast screening experts. It provides a structured format for breast screening committees to consider and discuss the values of themselves and others, suggests relevant topics for further inquiry and highlights areas of need for future research into the values of the public. It enables committees to publicly explain and justify their decisions with reference to values, improving transparency and accountability. It is intended to act alongside practices that seek to accommodate the values of individual women in the informed decision making process for personal decision making about participation in breast screening. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Induced mutations - a tool in plant research

    International Nuclear Information System (INIS)

    1981-01-01

    These proceedings include 34 papers and 18 brief descriptions of poster presentations in the following areas as they are affected by induced mutations: advancement of genetics, plant evolution, plant physiology, plant parasites, plant symbioses, in vitro culture, gene ecology and plant breeding. Only a relatively small number of papers are of direct nuclear interest essentially in view of the mutations being induced by ionizing radiations. The papers of nuclear interest have been entered as separate and individual items of input

  4. Validation of a new assessment tool for qualitative research articles

    DEFF Research Database (Denmark)

    Schou, Lone; Høstrup, Helle; Lyngsø, Elin

    2012-01-01

    are not aware of an assessment tool that is validated and applicable, not only for researchers but also for clinicians with different levels of training and experience in reading research articles. Method.  In three phases from 2007 to 2009 we delevoped and tested such an assessment tool called VAKS, which...... is the Danish acronym for Appraisal of Qualitative Studies. Phase 1 was to develop the tool based on a literature review and on consultation with qualitative researchers. Phase 2 was an inter-rater reliability test in which 40 health professionals participated. Phase 3 was an inter-rater reliability test among......-rater agreement was acceptable, but disagreement was seen for some items. Conclusion.  We have developed an assessment tool for appraisal of qualitative research studies. Nurses with a range of formal education and experience in reading research articles are able to appraise, relatively consistently, articles...

  5. Creative Activism: a pedagogical and research tool

    Directory of Open Access Journals (Sweden)

    Ruth Morrow

    2012-11-01

    research projects and partnerships. UK Universities talk extensively about applied research but have few actual strategies by which to generate it. Fourdaysontheoutside offers some potential ways forward.

  6. Joint Road Forward: a new set of tools for including excluded perspectives on transport infrastructure

    NARCIS (Netherlands)

    Krishna, H.; Palavalli, B; Frank, A.F.C.; Meijer, S; Subrahmanian, E

    2016-01-01

    Planning of transportation infrastructure is built upon an established set of planning methods to estimate the need for and specifications of roads, amongst others. The abstraction from the real world as needed for applying clear planning tools has grown to considerably differ from the complex urban

  7. The Value of Open Source Software Tools in Qualitative Research

    Science.gov (United States)

    Greenberg, Gary

    2011-01-01

    In an era of global networks, researchers using qualitative methods must consider the impact of any software they use on the sharing of data and findings. In this essay, I identify researchers' main areas of concern regarding the use of qualitative software packages for research. I then examine how open source software tools, wherein the publisher…

  8. Research Tools and Materials | NCI Technology Transfer Center | TTC

    Science.gov (United States)

    Research Tools can be found in TTC's Available Technologies and in scientific publications. They are freely available to non-profits and universities through a Material Transfer Agreement (or other appropriate mechanism), and available via licensing to companies.

  9. Survey design research: a tool for answering nursing research questions.

    Science.gov (United States)

    Siedlecki, Sandra L; Butler, Robert S; Burchill, Christian N

    2015-01-01

    The clinical nurse specialist is in a unique position to identify and study clinical problems in need of answers, but lack of time and resources may discourage nurses from conducting research. However, some research methods can be used by the clinical nurse specialist that are not time-intensive or cost prohibitive. The purpose of this article is to explain the utility of survey methodology for answering a number of nursing research questions. The article covers survey content, reliability and validity issues, sample size considerations, and methods of survey delivery.

  10. Aligning Web-Based Tools to the Research Process Cycle: A Resource for Collaborative Research Projects

    Science.gov (United States)

    Price, Geoffrey P.; Wright, Vivian H.

    2012-01-01

    Using John Creswell's Research Process Cycle as a framework, this article describes various web-based collaborative technologies useful for enhancing the organization and efficiency of educational research. Visualization tools (Cacoo) assist researchers in identifying a research problem. Resource storage tools (Delicious, Mendeley, EasyBib)…

  11. Development of a data capture tool for researching tech entrepreneurship

    DEFF Research Database (Denmark)

    Andersen, Jakob Axel Bejbro; Howard, Thomas J.; McAloone, Tim C.

    2014-01-01

    Startups play a crucial role in exploiting the commercial advantages created by new, advanced technologies. Surprisingly, the processes by which the entrepreneur commercialises these technologies are largely undescribed - partly due to the absence of appropriate process data capture tools....... This paper elucidates the requirements for such tools by drawing on knowledge of the entrepreneurial phenomenon and by building on the existing research tools used in design research. On this basis, the development of a capture method for tech startup processes is described and its potential discussed....

  12. The use of web2 tools in action research

    DEFF Research Database (Denmark)

    Kolbæk, Raymond; Steensgaard, Randi; Angel, Sanne

    2017-01-01

    . Furthermore we try to evidence-based the concept of "Sample handlings" and examines whether this concept can be used as a flexible methodological tool for developing workflow that promotes patient participation in their own rehabilitation. We use a action research design to identify actual problems, develop...... and the researchers themselves have felt strange and confused about the use of online tools. For example, some of the participants did not want to use Facebook as a communication medium, as several did not have a Facebook account, while others would not want to mix work and leisure together. The web2 tools used...

  13. Serious Games are a Serious Tool for Team Research

    Directory of Open Access Journals (Sweden)

    Michael D. Coovert

    2017-03-01

    Full Text Available Serious games are an attractive tool for education and training, but their utility is even broader. We argue serious games provide a unique opportunity for research as well, particularly in areas where multiple players (groups or teams are involved. In our paper we provide background in several substantive areas. First, we outline major constructs and challenges found in team research. Secondly, we discuss serious games, providing an overview and description of their role in education, training, and research. Thirdly, we describe necessary characteristics for game engines utilized in team research, followed by a discussion of the value added by utilizing serious games. Our goal in this paper is to argue serious games are an effective tool with demonstrated reliability and validity and should be part of a research program for those engaged in team research. Both team researchers and those involved in serious game development can benefit from a mutual partnership which is research focused.

  14. SAGE Research Methods Datasets: A Data Analysis Educational Tool.

    Science.gov (United States)

    Vardell, Emily

    2016-01-01

    SAGE Research Methods Datasets (SRMD) is an educational tool designed to offer users the opportunity to obtain hands-on experience with data analysis. Users can search for and browse authentic datasets by method, discipline, and data type. Each of the datasets are supplemented with educational material on the research method and clear guidelines for how to approach data analysis.

  15. Thermoluminescence as a Research Tool to Investigate Luminescence Mechanisms

    NARCIS (Netherlands)

    Bos, A.J.J.

    2017-01-01

    Thermally stimulated luminescence (TSL) is known as a technique used in radiation dosimetry and dating. However, since the luminescence is very sensitive to the defects in a solid, it can also be used in material research. In this review, it is shown how TSL can be used as a research tool to

  16. The WWW Cabinet of Curiosities: A Serendipitous Research Tool

    Science.gov (United States)

    Arnold, Josie

    2012-01-01

    This paper proposes that the WWW is able to be fruitfully understood as a research tool when we utilise the metaphor of the cabinet of curiosities, the wunderkammer. It unpeels some of the research attributes of the metaphor as it reveals the multiplicity of connectivity on the web that provides serendipitous interactions between unexpected…

  17. University Knowledge Management Tool for Academic Research Activity Evaluation

    Directory of Open Access Journals (Sweden)

    Mihaela OPREA

    2011-01-01

    Full Text Available The implementation of an efficient university knowledge management system involves the de-velopment of several software tools that assist the decision making process for the three main activities of a university: teaching, research, and management. Artificial intelligence provides a variety of techniques that can be used by such tools: machine learning, data mining, text mining, knowledge based systems, expert systems, case-based reasoning, decision support systems, intelligent agents etc. In this paper it is proposed a generic structure of a university knowledge management system, and it is presented an expert system, ACDI_UPG, developed for academic research activity evaluation, that can be used as a decision support tool by the university knowledge management system for planning future research activities according to the main objectives of the university and of the national / international academic research funding organizations.

  18. Researching and deploying an APEX security scanning tool

    CERN Document Server

    Vali, Silvia

    2016-01-01

    Most of the APEX applications have not been developed considering security in mind or were developed many years ago, as well as the old version of APEX used exposes those type of applications to a variety of potential security risks. CERN develops and uses many APEX applications, but none of the currently used tools provides a sufficient way of vulnerability scanning for such applications. The current version of APEX used in CERN is 4.2.6 whilst the latest version is 5.1. This report provides the reader with the overview on APEX and the APEX-SERT vulnerability scanning tool as well as the summary of testing the APEX-SERT tool on existing APEX applications used in CERN and the samples, created during this project. The goal of this project was to research on existing tools for vulnerability scanning of APEX applications and to deploy the tool to be used APEX developers.

  19. The "Metaphorical Collage" as a Research Tool in the Field of Education

    Science.gov (United States)

    Russo-Zimet, Gila

    2016-01-01

    The aim of this paper is to propose a research tool in the field of education--the "metaphorical collage." This tool facilitates the understanding of concepts and processes in education through the analysis of metaphors in collage works that include pictorial images and verbal images. We believe the "metaphorical collage" to be…

  20. Saliva as a potential tool for diagnosis of dry mouth including Sjögren's syndrome.

    Science.gov (United States)

    Ohyama, K; Moriyama, M; Hayashida, J-N; Tanaka, A; Maehara, T; Ieda, S; Furukawa, S; Ohta, M; Imabayashi, Y; Nakamura, S

    2015-03-01

    Recently, the use of saliva as a diagnostic tool has gained considerable attention because it is non-invasive and easy to perform repeatedly. In this study, we focused on soluble molecules in saliva to establish a new diagnostic method for xerostomia. Saliva was obtained from 90 patients with Sjögren's syndrome (SS), 22 patients with xerostomia associated with neurogenic/neuropsychiatric disorders and drugs (XND), 30 patients with radiation-induced xerostomia (RX), and 36 healthy controls. Concentrations of helper T (Th) cytokines in saliva were measured by flow cytometric analysis. Concentrations of secretory IgA (SIgA) and chromogranin A (CgA) were measured by ELISA. Unstimulated and stimulated whole saliva from patients with SS, XND, and RX was significantly reduced compared with controls. Th1 and Th2 cytokines from SS patients were significantly higher than controls. Furthermore, Th2 cytokines were closely associated with strong lymphocytic accumulation in salivary glands from SS patients, while Th1 and Th17 cytokines were negatively associated. SIgA levels were not significantly different between all patient groups and controls. CgA levels from XND patients were significantly higher than controls. The measurement of cytokines, CgA, and SIgA in saliva is suggested to be useful for the diagnosis of xerostomia and also to reveal disease status. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. Participant-centric initiatives: Tools to facilitate engagement in research

    Directory of Open Access Journals (Sweden)

    Nicholas Anderson

    2012-12-01

    Full Text Available Clinical genomic research faces increasing challenges in establishing participant privacy and consent processes that facilitate meaningful choice and communication capacity for longitudinal and secondary research uses. There are an evolving range of participant-centric initiatives that combine web-based informatics tools with new models of engagement and research collaboration. These emerging initiatives may become valuable approaches to support large-scale and longitudinal research studies. We highlight and discuss four types of emerging initiatives for engaging and sustaining participation in research.

  2. Integrative Biological Chemistry Program Includes the Use of Informatics Tools, GIS and SAS Software Applications

    Science.gov (United States)

    D'Souza, Malcolm J.; Kashmar, Richard J.; Hurst, Kent; Fiedler, Frank; Gross, Catherine E.; Deol, Jasbir K.; Wilson, Alora

    2015-01-01

    Wesley College is a private, primarily undergraduate minority-serving institution located in the historic district of Dover, Delaware (DE). The College recently revised its baccalaureate biological chemistry program requirements to include a one-semester Physical Chemistry for the Life Sciences course and project-based experiential learning…

  3. A PART OF RESEARCH METHODOLOGY COURSE: Introduction to the Research Tools

    OpenAIRE

    Ebrahim, Nader Ale

    2016-01-01

    Research Tools” can be defined as vehicles that broadly facilitate research and related activities. “Research Tools” enable researchers to collect, organize, analyze, visualize and publicized research  outputs. Dr. Nader has collected over 800 tools that enable students to follow the correct path in research and to ultimately produce high-quality research outputs with more accuracy and efficiency. It is assembled as an interactive Web-based mind map, titled “Research Tools”, which is updated...

  4. Software Tools | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    The CPTAC program develops new approaches to elucidate aspects of the molecular complexity of cancer made from large-scale proteogenomic datasets, and advance them toward precision medicine.  Part of the CPTAC mission is to make data and tools available and accessible to the greater research community to accelerate the discovery process.

  5. How novice, skilled and advanced clinical researchers include variables in a case report form for clinical research: a qualitative study.

    Science.gov (United States)

    Chu, Hongling; Zeng, Lin; Fetters, Micheal D; Li, Nan; Tao, Liyuan; Shi, Yanyan; Zhang, Hua; Wang, Xiaoxiao; Li, Fengwei; Zhao, Yiming

    2017-09-18

    Despite varying degrees in research training, most academic clinicians are expected to conduct clinical research. The objective of this research was to understand how clinical researchers of different skill levels include variables in a case report form for their clinical research. The setting for this research was a major academic institution in Beijing, China. The target population was clinical researchers with three levels of experience, namely, limited clinical research experience, clinicians with rich clinical research experience and clinical research experts. Using a qualitative approach, we conducted 13 individual interviews (face to face) and one group interview (n=4) with clinical researchers from June to September 2016. Based on maximum variation sampling to identify researchers with three levels of research experience: eight clinicians with limited clinical research experience, five clinicians with rich clinical research experience and four clinical research experts. These 17 researchers had diverse hospital-based medical specialties and or specialisation in clinical research. Our analysis yields a typology of three processes developing a case report form that varies according to research experience level. Novice clinician researchers often have an incomplete protocol or none at all, and conduct data collection and publication based on a general framework. Experienced clinician researchers include variables in the case report form based on previous experience with attention to including domains or items at risk for omission and by eliminating unnecessary variables. Expert researchers consider comprehensively in advance data collection and implementation needs and plan accordingly. These results illustrate increasing levels of sophistication in research planning that increase sophistication in selection for variables in the case report form. These findings suggest that novice and intermediate-level researchers could benefit by emulating the comprehensive

  6. 75 FR 11914 - Chrysler, LLC, Mount Elliott Tool and Die, Including On-Site Leased Workers From Modern...

    Science.gov (United States)

    2010-03-12

    ... Elliott Tool and Die, Including On-Site Leased Workers From Modern Professional Services, TAC Automotive... Certification Regarding Eligibility To Apply for Worker Adjustment Assistance and Alternative Trade Adjustment Assistance In accordance with Section 223 of the Trade Act of 1974 (19 U.S.C. 2273), and Section 246 of the...

  7. Development of a 'ready-to-use' tool that includes preventability, for the assessment of adverse drug events in oncology.

    Science.gov (United States)

    Hébert, Guillaume; Netzer, Florence; Kouakou, Sylvain Landry; Lemare, François; Minvielle, Etienne

    2018-02-14

    Background Adverse drug events (ADEs) occur frequently in oncology and justify continuous assessment and monitoring. There are several methods for detecting them, but the trigger tool method seems the most appropriate. Although a generic tool exists, its use for ADEs in oncology has not been convincing. The development of a focused version is therefore necessary. Objective To provide an oncology-focused trigger tool that evaluates the prevalence, harm, and preventability in a standardised method for pragmatic use in ADE surveillance. Setting Hospitals with cancer care in France. Method The tool has been constructed in two steps: (1) constitution of an oncology-centred list of ADEs; 30 pharmacists/practitioners in cancer care from nine hospitals selected a list of ADEs using a method of agreement adapted from the RAND/UCLA Appropriateness Method; and (2) construction of three standardised dimensions for the characterisation of each ADE (including causality, severity, and preventability). Main outcome measure The main outcome measure was validation of the tool, including preventability criteria. Results The tool is composed of a final list of 15 ADEs. For each ADE, a 'reviewer form' has been designed and validated by the panel. It comprises (1) the trigger(s), (2) flowcharts to guide the reviewer, (3) criteria for grading harm, and (4) a standardised assessment of preventability with 6-14 closed sentences for each ADE in terms of therapeutic management and/or prevention of side-effects. Conclusion A complete 'ready-to-use' tool for ADE monitoring in oncology has been developed that allows the assessment of three standardised dimensions.

  8. Bioinformatics resources for cancer research with an emphasis on gene function and structure prediction tools

    Directory of Open Access Journals (Sweden)

    Daisuke Kihara

    2006-01-01

    Full Text Available The immensely popular fields of cancer research and bioinformatics overlap in many different areas, e.g. large data repositories that allow for users to analyze data from many experiments (data handling, databases, pattern mining, microarray data analysis, and interpretation of proteomics data. There are many newly available resources in these areas that may be unfamiliar to most cancer researchers wanting to incorporate bioinformatics tools and analyses into their work, and also to bioinformaticians looking for real data to develop and test algorithms. This review reveals the interdependence of cancer research and bioinformatics, and highlight the most appropriate and useful resources available to cancer researchers. These include not only public databases, but general and specific bioinformatics tools which can be useful to the cancer researcher. The primary foci are function and structure prediction tools of protein genes. The result is a useful reference to cancer researchers and bioinformaticians studying cancer alike.

  9. The importance of moral sensitivity when including persons with dementia in qualitative research.

    Science.gov (United States)

    Heggestad, Anne Kari T; Nortvedt, Per; Slettebø, Åshild

    2013-02-01

    The aim of this article is to show the importance of moral sensitivity when including persons with dementia in research. The article presents and discusses ethical challenges encountered when a total of 15 persons with dementia from two nursing homes and seven proxies were included in a qualitative study. The examples show that the ethical challenges may be unpredictable. As researchers, you participate with the informants in their daily life and in the interviews, and it is not possible to plan all that may happen during the research. A procedural proposal to an ethical committee at the beginning of a research project based on traditional research ethical principles may serve as a guideline, but it cannot solve all the ethical problems one faces during the research process. Our main argument in this article is, therefore, that moral sensitivity is required in addition to the traditional research ethical principles throughout the whole process of observing and interviewing the respondents.

  10. Clinical Nursing Research: A Tool for Professional Development ...

    African Journals Online (AJOL)

    These and many more require the best available evidence, which could be acquired through CNR. However to achieve the benefits of CNR for professional development, Challenges including low quality research by new and inexperienced researchers; non-availability of research findings to nurses in the practice sectors; ...

  11. A global call for action to include gender in research impact assessment.

    Science.gov (United States)

    Ovseiko, Pavel V; Greenhalgh, Trisha; Adam, Paula; Grant, Jonathan; Hinrichs-Krapels, Saba; Graham, Kathryn E; Valentine, Pamela A; Sued, Omar; Boukhris, Omar F; Al Olaqi, Nada M; Al Rahbi, Idrees S; Dowd, Anne-Maree; Bice, Sara; Heiden, Tamika L; Fischer, Michael D; Dopson, Sue; Norton, Robyn; Pollitt, Alexandra; Wooding, Steven; Balling, Gert V; Jakobsen, Ulla; Kuhlmann, Ellen; Klinge, Ineke; Pololi, Linda H; Jagsi, Reshma; Smith, Helen Lawton; Etzkowitz, Henry; Nielsen, Mathias W; Carrion, Carme; Solans-Domènech, Maite; Vizcaino, Esther; Naing, Lin; Cheok, Quentin H N; Eckelmann, Baerbel; Simuyemba, Moses C; Msiska, Temwa; Declich, Giovanna; Edmunds, Laurel D; Kiparoglou, Vasiliki; Buchan, Alison M J; Williamson, Catherine; Lord, Graham M; Channon, Keith M; Surender, Rebecca; Buchan, Alastair M

    2016-07-19

    Global investment in biomedical research has grown significantly over the last decades, reaching approximately a quarter of a trillion US dollars in 2010. However, not all of this investment is distributed evenly by gender. It follows, arguably, that scarce research resources may not be optimally invested (by either not supporting the best science or by failing to investigate topics that benefit women and men equitably). Women across the world tend to be significantly underrepresented in research both as researchers and research participants, receive less research funding, and appear less frequently than men as authors on research publications. There is also some evidence that women are relatively disadvantaged as the beneficiaries of research, in terms of its health, societal and economic impacts. Historical gender biases may have created a path dependency that means that the research system and the impacts of research are biased towards male researchers and male beneficiaries, making it inherently difficult (though not impossible) to eliminate gender bias. In this commentary, we - a group of scholars and practitioners from Africa, America, Asia and Europe - argue that gender-sensitive research impact assessment could become a force for good in moving science policy and practice towards gender equity. Research impact assessment is the multidisciplinary field of scientific inquiry that examines the research process to maximise scientific, societal and economic returns on investment in research. It encompasses many theoretical and methodological approaches that can be used to investigate gender bias and recommend actions for change to maximise research impact. We offer a set of recommendations to research funders, research institutions and research evaluators who conduct impact assessment on how to include and strengthen analysis of gender equity in research impact assessment and issue a global call for action.

  12. Script Towards Research 2.0: The Influence of Digital and Online Tools in Academic Research

    Directory of Open Access Journals (Sweden)

    Gabriela Grosseck

    2016-07-01

    Full Text Available The new Internet technologies have infiltrated in a stunning way the academic environment, both at individual and at institutional level. Therefore, more and more teachers have started educational blogs, librarians are active on Twitter, other educational actors curate web content, students post on Instagram or Flickr, and university departments have Facebook pages and/or YouTube accounts etc. Today, the use of web technology has become “a legitimate activity in many areas of higher education” (Waycott, 2010 and a considerable shift to digital academic research has gradually occurred. Teachers are encouraging students to take up digital tools for research and writing, thus revealing new ways of using information and communication technologies for academic purposes and not just for socializing. The main objective of this paper is to investigate the effects of integrating diverse digital, Web 2.0 tools and resources and OERs/MOOCs in research and in the construction of students’ academic texts. We aim to stress the increasing influence of digital and online tools in academic research and writing. Teachers, specialists, and students alike are affected by this process. In order to show how, we explore the following issues: What is Research 2.0? Which digital/online tools have we used to assist our students? What are the challenges for academic research using digital / web 2.0 tools? And how do digital tools shape academic research?

  13. [Research progress of whole embryo culture tool and its application].

    Science.gov (United States)

    Han, Jiayin; Liang, Aihua

    2010-03-01

    Whole embryo culture (WEC) is an experimental tool, which is made use of embryos in vitro to replace whole animals to investigate the growth and development of early organs, the embryo toxicity of chemical materials and the mechanism of the occurrence of embryo toxicity. Compared with experiment with whole animals, WEC could reduce the number of experimental animals, shorten experimental time, decrease experimental expenses, eliminate disturbing factors and control dosage more exactly. So it is generally received that WEC tool is a good experimental method to match the principles of replacement, reduction, refinement and responsibility. This article is a review of the WEC tool of rat and mouse, including the development of this tool, announcements, and the application in the development of organs, the embryo toxicity of environmental pollution and heavy metal, safety evaluation of medicine and the embryo toxicity of traditional Chinese medicine and its mechanism. There is also a discussion of the application of this tool in the investigation of the embryo toxicity of traditional Chinese medicine.

  14. Environmental equity research: review with focus on outdoor air pollution research methods and analytic tools.

    Science.gov (United States)

    Miao, Qun; Chen, Dongmei; Buzzelli, Michael; Aronson, Kristan J

    2015-01-01

    The objective of this study was to review environmental equity research on outdoor air pollution and, specifically, methods and tools used in research, published in English, with the aim of recommending the best methods and analytic tools. English language publications from 2000 to 2012 were identified in Google Scholar, Ovid MEDLINE, and PubMed. Research methodologies and results were reviewed and potential deficiencies and knowledge gaps identified. The publications show that exposure to outdoor air pollution differs by social factors, but findings are inconsistent in Canada. In terms of study designs, most were small and ecological and therefore prone to the ecological fallacy. Newer tools such as geographic information systems, modeling, and biomarkers offer improved precision in exposure measurement. Higher-quality research using large, individual-based samples and more precise analytic tools are needed to provide better evidence for policy-making to reduce environmental inequities.

  15. Conducting Accessible Research: Including People With Disabilities in Public Health, Epidemiological, and Outcomes Studies.

    Science.gov (United States)

    Rios, Dianne; Magasi, Susan; Novak, Catherine; Harniss, Mark

    2016-12-01

    People with disabilities are largely absent from mainstream health research. Exclusion of people with disabilities may be explicit, attributable to poorly justified exclusion criteria, or implicit, attributable to inaccessible study documents, interventions, or research measures. Meanwhile, people with disabilities experience poorer health, greater incidence of chronic conditions, and higher health care expenditure than people without disabilities. We outline our approach to "accessible research design"-research accessible to and inclusive of people with disabilities. We describe a model that includes 3 tiers: universal design, accommodations, and modifications. Through our work on several large-scale research studies, we provide pragmatic examples of accessible research design. Making efforts to include people with disabilities in public health, epidemiological, and outcomes studies will enhance the interpretability of findings for a significant patient population.

  16. Using Photovoice to Include People with Profound and Multiple Learning Disabilities in Inclusive Research

    Science.gov (United States)

    Cluley, Victoria

    2017-01-01

    Background: It is now expected that projects addressing the lives of people with learning disabilities include people with learning disabilities in the research process. In the past, such research often excluded people with learning disabilities, favouring the opinions of family members, carers and professionals. The inclusion of the voices of…

  17. The Research Tools of the Virtual Astronomical Observatory

    Science.gov (United States)

    Hanisch, Robert J.; Berriman, G. B.; Lazio, T. J.; Project, VAO

    2013-01-01

    Astronomy is being transformed by the vast quantities of data, models, and simulations that are becoming available to astronomers at an ever-accelerating rate. The U.S. Virtual Astronomical Observatory (VAO) has been funded to provide an operational facility that is intended to be a resource for discovery and access of data, and to provide science services that use these data. Over the course of the past year, the VAO has been developing and releasing for community use five science tools: 1) "Iris", for dynamically building and analyzing spectral energy distributions, 2) a web-based data discovery tool that allows astronomers to identify and retrieve catalog, image, and spectral data on sources of interest, 3) a scalable cross-comparison service that allows astronomers to conduct pair-wise positional matches between very large catalogs stored remotely as well as between remote and local catalogs, 4) time series tools that allow astronomers to compute periodograms of the public data held at the NASA Star and Exoplanet Database (NStED) and the Harvard Time Series Center, and 5) A VO-aware release of the Image Reduction and Analysis Facility (IRAF) that provides transparent access to VO-available data collections and is SAMP-enabled, so that IRAF users can easily use tools such as Aladin and Topcat in conjuction with IRAF tasks. Additional VAO services will be built to make it easy for researchers to provide access to their data in VO-compliant ways, to build VO-enabled custom applications in Python, and to respond generally to the growing size and complexity of astronomy data. Acknowledgements: The Virtual Astronomical Observatory (VAO) is managed by the VAO, LLC, a non-profit company established as a partnership of the Associated Universities, Inc. and the Association of Universities for Research in Astronomy, Inc. The VAO is sponsored by the National Science Foundation and the National Aeronautics and Space Administration.

  18. Accounting Research as a didactic tool for a accounting teaching

    Directory of Open Access Journals (Sweden)

    Valeria Gisela Perez

    2016-06-01

    Full Text Available This paper develops a reflection about the importance of the research of accounting subjects in the professional accountants training, this importance is an attribute of research to increase the wealth of discipline under investigation, this can be converted into a skill and/or competence wich accountants are required to demonstrate in their professional practice.Furthermore, accounting is recognized by the authors as a science in constant development, being able to be investigated. This change in knowledge is an element that motivates professionals to be constantly updated, becoming this aspect (constant updating the skill and competence that research can bring to professional training in university classrooms.The reflection is based on the study of documents developed by prestigious authors in accounting theory, teaching and research.Therefore, this paper concludes that research is a useful tool for the professional accounting training, and rewards the important skills and competencies for professional practice; it can be conceived as well as a strategy for technical and educational activities that allows students to recreate knowledge, allowing future updates that will require their professional practice.Key words: Accounting research, university teaching, accounting education. 

  19. Electric gun: a new tool for ultrahigh-pressure research

    International Nuclear Information System (INIS)

    Weingart, R.C.; Chau, H.H.; Goosman, D.R.; Hofer, W.W.; Honodel, C.A.; Lee, R.S.; Steinberg, D.J.; Stroud, J.R.

    1979-01-01

    We have developed a new tool for ultrahigh-pressure research at LLL. This system, which we call the electric gun, has already achieved thin flyer plate velocities in excess of 20 km/s and pressures of the order of 2 TPa in tantalum. We believe that the electric gun is competitive with laser- and nuclear-driven methods of producing shocks in the 1-to-5 TPa range because of its precision and ease and economy of operation. Its development is recommended for shock initiation studies, dry runs for Site 300 hydroshots, and as a shock wave generator for surface studies

  20. Research in space science and technology. [including X-ray astronomy and interplanetary plasma physics

    Science.gov (United States)

    Beckley, L. E.

    1977-01-01

    Progress in various space flight research programs is reported. Emphasis is placed on X-ray astronomy and interplanetary plasma physics. Topics covered include: infrared astronomy, long base line interferometry, geological spectroscopy, space life science experiments, atmospheric physics, and space based materials and structures research. Analysis of galactic and extra-galactic X-ray data from the Small Astronomy Satellite (SAS-3) and HEAO-A and interplanetary plasma data for Mariner 10, Explorers 47 and 50, and Solrad is discussed.

  1. Evaluating research impact: the development of a ‘RESEARCH for IMPACT’ TOOL

    Directory of Open Access Journals (Sweden)

    Komla Tsey

    2016-08-01

    Full Text Available Introduction: This paper describes the development of a ‘Research for Impact’ Tool against a background of concerns about the over-researching of Aboriginal and Torres Strait Islander people’s issues without demonstrable benefits.Material and Methods: A combination of literature reviews, workshops with researchers and reflections by project team members and partners using participatory snowball techniques.Results: Assessing research impact is difficult, akin to so-called ‘wicked problem’, but not impossible. Heuristic and collaborative approach to research that takes in the expectations of research users, those being researched and the funders of research offers a pragmatic solution to evaluating research impact. The proposed ‘Research for Impact’ Tool is based on the understanding that the value of research is to create evidence and/or products to support smarter decisions so as to improve the human condition.Research is of limited value unless the evidence produced is used to inform smarter decisions. A practical way of approaching research impact is therefore to start with the decisions confronting decision makers whether they are government policymakers, professional practitioners or households and the extent to which the research supports smarter decisions and the knock-on consequences of such smart decisions. Embedded at each step in the impact planning, monitoring and evaluation process is the need for Indigenous leadership and participation, capacity enhancement and collaborative partnerships and participatory learning by doing approaches across partners.Discussion: The tool is designed in the context of Indigenous research but the basic idea that the way to assess research impact is to start upfront by defining the users’ of research and their information needs, the decisions confronting them and the extent to which research informs smarter decisions is equally applicable to research in other settings, both applied and

  2. Operations other than war: Requirements for analysis tools research report

    Energy Technology Data Exchange (ETDEWEB)

    Hartley, D.S. III

    1996-12-01

    This report documents the research effort to determine the requirements for new or improved analysis tools to support decisions at the strategic and operational levels for military Operations Other than War (OOTW). The work was performed for the Commander in Chief, U.S. Pacific Command (USCINCPAC). The data collection was based on workshops attended by experts in OOTWs: analysis personnel from each of the Combatant Commands, the Services, the Office of the Secretary of Defense (OSD), the Joint Staff, and other knowledgeable personnel. Further data were gathered from other workshops and conferences and from the literature. The results of this research begin with the creation of a taxonomy of OOTWs: categories of operations, attributes of operations, and tasks requiring analytical support. The tasks are connected to the Joint Staff`s Universal Joint Task List (UJTL). Historical OOTWs are analyzed to produce frequency distributions by category and responsible CINC. The analysis products are synthesized into a list of requirements for analytical tools and definitions of the requirements. The report concludes with a timeline or roadmap for satisfying the requirements.

  3. Including adults with intellectual disabilities who lack capacity to consent in research.

    Science.gov (United States)

    Calveley, Julie

    2012-07-01

    The Mental Capacity Act 2005 has stipulated that in England and Wales the ethical implications of carrying out research with people who are unable to consent must be considered alongside the ethical implications of excluding them from research altogether. This paper describes the methods that were used to enable people with severe and profound intellectual disabilities, who lacked capacity, to participate in a study that examined their experience of receiving intimate care. The safeguards that were put in place to protect the rights and well-being of participants are described, and it is argued that the approaches used in this study met the requirements set out in the Mental Capacity Act 2005. Although this paper is based on research involving people with intellectual disabilities, it has implications for research involving other groups who may also lack capacity to consent, including people with mental health problems, head injuries and dementia.

  4. Twitter as a Tool for Health Research: A Systematic Review.

    Science.gov (United States)

    Sinnenberg, Lauren; Buttenheim, Alison M; Padrez, Kevin; Mancheno, Christina; Ungar, Lyle; Merchant, Raina M

    2017-01-01

    Researchers have used traditional databases to study public health for decades. Less is known about the use of social media data sources, such as Twitter, for this purpose. To systematically review the use of Twitter in health research, define a taxonomy to describe Twitter use, and characterize the current state of Twitter in health research. We performed a literature search in PubMed, Embase, Web of Science, Google Scholar, and CINAHL through September 2015. We searched for peer-reviewed original research studies that primarily used Twitter for health research. Two authors independently screened studies and abstracted data related to the approach to analysis of Twitter data, methodology used to study Twitter, and current state of Twitter research by evaluating time of publication, research topic, discussion of ethical concerns, and study funding source. Of 1110 unique health-related articles mentioning Twitter, 137 met eligibility criteria. The primary approaches for using Twitter in health research that constitute a new taxonomy were content analysis (56%; n = 77), surveillance (26%; n = 36), engagement (14%; n = 19), recruitment (7%; n = 9), intervention (7%; n = 9), and network analysis (4%; n = 5). These studies collectively analyzed more than 5 billion tweets primarily by using the Twitter application program interface. Of 38 potential data features describing tweets and Twitter users, 23 were reported in fewer than 4% of the articles. The Twitter-based studies in this review focused on a small subset of data elements including content analysis, geotags, and language. Most studies were published recently (33% in 2015). Public health (23%; n = 31) and infectious disease (20%; n = 28) were the research fields most commonly represented in the included studies. Approximately one third of the studies mentioned ethical board approval in their articles. Primary funding sources included federal (63%), university (13%), and foundation

  5. 'Including health in systems responsible for urban planning': a realist policy analysis research programme.

    Science.gov (United States)

    Harris, Patrick; Friel, Sharon; Wilson, Andrew

    2015-07-23

    Realist methods are increasingly being used to investigate complex public health problems. Despite the extensive evidence base clarifying the built environment as a determinant of health, there is limited knowledge about how and why land-use planning systems take on health concerns. Further, the body of research related to the wider determinants of health suffers from not using political science knowledge to understand how to influence health policy development and systems. This 4-year funded programme of research investigates how the land-use planning system in New South Wales, Australia, incorporates health and health equity at multiple levels. The programme uses multiple qualitative methods to develop up to 15 case studies of different activities of the New South Wales land-use planning system. Comparison cases from other jurisdictions will be included where possible and useful. Data collection includes publicly available documentation and purposively sampled stakeholder interviews and focus groups of up to 100 participants across the cases. The units of analysis in each case are institutional structures (rules and mandates constraining and enabling actors), actors (the stakeholders, organisations and networks involved, including health-focused agencies), and ideas (policy content, information, and framing). Data analysis will focus on and develop propositions concerning the mechanisms and conditions within and across each case leading to inclusion or non-inclusion of health. Data will be refined using additional political science and sociological theory. Qualitative comparative analysis will compare cases to develop policy-relevant propositions about the necessary and sufficient conditions needed to include health issues. Ethics has been approved by Sydney University Human Research Ethics Committee (2014/802 and 2015/178). Given the nature of this research we will incorporate stakeholders, often as collaborators, throughout. We outline our research translation

  6. Global Health Education for Medical Students: When Learning Objectives Include Research.

    Science.gov (United States)

    Bales, Alison M; Oddo, Anthony R; Dennis, David J; Siska, Robert C; VanderWal, Echo; VanderWal, Harry; Dlamini, Nompumelelo; Markert, Ronald J; McCarthy, Mary C

    2017-10-05

    The Luke Commission, a provider of comprehensive mobile health outreach in rural Swaziland, focuses on human immunodeficiency virus testing and prevention, including the performance of over 100 circumcisions weekly. Educational objectives for medical student global health electives are essential. Learning research methodology while engaging in clinical activities reinforces curriculum goals. Medical care databases can produce clinically significant findings affecting international health policy. Engaging in academic research exponentially increased the educational value of student experiences during an international medical elective. Staff of the Luke Commission, a nongovernmental organization, collected and deidentified information from 1500 Swazi male patients undergoing circumcision from January through June of 2014. Medical students designed studies and analyzed these data to produce research projects on adverse event rates, pain perception, and penile malformations. Institutional review board approval was obtained from the home institution and accompanying senior surgical faculty provided mentorship. First-year medical students enrolled in an international medical elective to explore resource availability, cultural awareness, health care provision, and developing world endemic diseases. While in country, students learned research methodology, collected data, and engaged in research projects. Following the trip, students presented posters at over 10 regional and national meetings. All 4 articles are accepted or under consideration for publication by major journals. During international medical electives the combination of clinical experiences and access to databases from health aid organizations provides the foundation for productive medical student research. All participants benefit from the relationships formed by aid organizations, medical students, and patient populations. Global health research has many complexities, but through careful planning and

  7. Effective Tooling for Linked Data Publishing in Scientific Research

    Energy Technology Data Exchange (ETDEWEB)

    Purohit, Sumit; Smith, William P.; Chappell, Alan R.; West, Patrick; Lee, Benno; Stephan, Eric G.; Fox, Peter

    2016-02-05

    Challenges that make it difficult to find, share, and combine published data, such as data heterogeneity and resource discovery, have led to increased adoption of semantic data standards and data publishing technologies. To make data more accessible, interconnected and discoverable, some domains are being encouraged to publish their data as Linked Data. Consequently, this trend greatly increases the amount of data that semantic web tools are required to process, store, and interconnect. In attempting to process and manipulate large data sets, tools–ranging from simple text editors to modern triplestores– eventually breakdown upon reaching undefined thresholds. This paper offers a systematic approach that data publishers can use to categorize suitable tools to meet their data publishing needs. We present a real-world use case, the Resource Discovery for Extreme Scale Collaboration (RDESC), which features a scientific dataset(maximum size of 1.4 billion triples) used to evaluate a toolbox for data publishing in climate research. This paper also introduces a semantic data publishing software suite developed for the RDESC project.

  8. Development of a research ethics knowledge and analytical skills assessment tool.

    Science.gov (United States)

    Taylor, Holly A; Kass, Nancy E; Ali, Joseph; Sisson, Stephen; Bertram, Amanda; Bhan, Anant

    2012-04-01

    The goal of this project was to develop and validate a new tool to evaluate learners' knowledge and skills related to research ethics. A core set of 50 questions from existing computer-based online teaching modules were identified, refined and supplemented to create a set of 74 multiple-choice, true/false and short answer questions. The questions were pilot-tested and item discrimination was calculated for each question. Poorly performing items were eliminated or refined. Two comparable assessment tools were created. These assessment tools were administered as a pre-test and post-test to a cohort of 58 Indian junior health research investigators before and after exposure to a new course on research ethics. Half of the investigators were exposed to the course online, the other half in person. Item discrimination was calculated for each question and Cronbach's α for each assessment tool. A final version of the assessment tool that incorporated the best questions from the pre-/post-test phase was used to assess retention of research ethics knowledge and skills 3 months after course delivery. The final version of the REKASA includes 41 items and had a Cronbach's α of 0.837. The results illustrate, in one sample of learners, the successful, systematic development and use of a knowledge and skills assessment tool in research ethics capable of not only measuring basic knowledge in research ethics and oversight but also assessing learners' ability to apply ethics knowledge to the analytical task of reasoning through research ethics cases, without reliance on essay or discussion-based examination. These promising preliminary findings should be confirmed with additional groups of learners.

  9. Computer planning tools applied to a cable logging research study

    Science.gov (United States)

    Chris B. LeDoux; Penn A. Peters

    1985-01-01

    Contemporary harvest planning software was used in planning the layout of cable logging units for a production study of the Clearwater Yarder in upstate New York. Planning software, including payload analysis and digital terrain models, allowed researchers to identify layout and yarding problems before the experiment. Analysis of proposed ground profiles pinpointed the...

  10. Thermoluminescence as a Research Tool to Investigate Luminescence Mechanisms.

    Science.gov (United States)

    Bos, Adrie J J

    2017-11-26

    Thermally stimulated luminescence (TSL) is known as a technique used in radiation dosimetry and dating. However, since the luminescence is very sensitive to the defects in a solid, it can also be used in material research. In this review, it is shown how TSL can be used as a research tool to investigate luminescent characteristics and underlying luminescent mechanisms. First, some basic characteristics and a theoretical background of the phenomenon are given. Next, methods and difficulties in extracting trapping parameters are addressed. Then, the instrumentation needed to measure the luminescence, both as a function of temperature and wavelength, is described. Finally, a series of very diverse examples is given to illustrate how TSL has been used in the determination of energy levels of defects, in the research of persistent luminescence phosphors, and in phenomena like band gap engineering, tunnelling, photosynthesis, and thermal quenching. It is concluded that in the field of luminescence spectroscopy, thermally stimulated luminescence has proven to be an experimental technique with unique properties to study defects in solids.

  11. Thermoluminescence as a Research Tool to Investigate Luminescence Mechanisms

    Science.gov (United States)

    2017-01-01

    Thermally stimulated luminescence (TSL) is known as a technique used in radiation dosimetry and dating. However, since the luminescence is very sensitive to the defects in a solid, it can also be used in material research. In this review, it is shown how TSL can be used as a research tool to investigate luminescent characteristics and underlying luminescent mechanisms. First, some basic characteristics and a theoretical background of the phenomenon are given. Next, methods and difficulties in extracting trapping parameters are addressed. Then, the instrumentation needed to measure the luminescence, both as a function of temperature and wavelength, is described. Finally, a series of very diverse examples is given to illustrate how TSL has been used in the determination of energy levels of defects, in the research of persistent luminescence phosphors, and in phenomena like band gap engineering, tunnelling, photosynthesis, and thermal quenching. It is concluded that in the field of luminescence spectroscopy, thermally stimulated luminescence has proven to be an experimental technique with unique properties to study defects in solids. PMID:29186873

  12. Thermoluminescence as a Research Tool to Investigate Luminescence Mechanisms

    Directory of Open Access Journals (Sweden)

    Adrie J. J. Bos

    2017-11-01

    Full Text Available Thermally stimulated luminescence (TSL is known as a technique used in radiation dosimetry and dating. However, since the luminescence is very sensitive to the defects in a solid, it can also be used in material research. In this review, it is shown how TSL can be used as a research tool to investigate luminescent characteristics and underlying luminescent mechanisms. First, some basic characteristics and a theoretical background of the phenomenon are given. Next, methods and difficulties in extracting trapping parameters are addressed. Then, the instrumentation needed to measure the luminescence, both as a function of temperature and wavelength, is described. Finally, a series of very diverse examples is given to illustrate how TSL has been used in the determination of energy levels of defects, in the research of persistent luminescence phosphors, and in phenomena like band gap engineering, tunnelling, photosynthesis, and thermal quenching. It is concluded that in the field of luminescence spectroscopy, thermally stimulated luminescence has proven to be an experimental technique with unique properties to study defects in solids.

  13. Development of dosimetry tools for proton therapy research

    International Nuclear Information System (INIS)

    Kim, Jong-Won; Kim, Dogyun

    2010-01-01

    Dosimetry tools for proton therapy research have been developed to measure the properties of a therapeutic proton beam. A CCD camera-scintillation screen system, which can verify the 2D dose distribution of a scanning beam and can be used for proton radiography, was developed. Also developed were a large area parallel-plate ionization chamber and a multi-layer Faraday cup to monitor the beam current and to measure the beam energy, respectively. To investigate the feasibility of locating the distal dose falloff in real time during patient treatment, a prompt gamma measuring system composed of multi-layer shielding structures was then devised. The system worked well for a pristine proton beam. However, correlation between the distal dose falloff and the prompt gamma distribution was blurred by neutron background for a therapy beam formed by scattering method. We have also worked on the design of a Compton camera to image the 2D distribution of prompt gamma rays.

  14. Including mixed methods research in systematic reviews: examples from qualitative syntheses in TB and malaria control.

    Science.gov (United States)

    Atkins, Salla; Launiala, Annika; Kagaha, Alexander; Smith, Helen

    2012-04-30

    Health policy makers now have access to a greater number and variety of systematic reviews to inform different stages in the policy making process, including reviews of qualitative research. The inclusion of mixed methods studies in systematic reviews is increasing, but these studies pose particular challenges to methods of review. This article examines the quality of the reporting of mixed methods and qualitative-only studies. We used two completed systematic reviews to generate a sample of qualitative studies and mixed method studies in order to make an assessment of how the quality of reporting and rigor of qualitative-only studies compares with that of mixed-methods studies. Overall, the reporting of qualitative studies in our sample was consistently better when compared with the reporting of mixed methods studies. We found that mixed methods studies are less likely to provide a description of the research conduct or qualitative data analysis procedures and less likely to be judged credible or provide rich data and thick description compared with standalone qualitative studies. Our time-related analysis shows that for both types of study, papers published since 2003 are more likely to report on the study context, describe analysis procedures, and be judged credible and provide rich data. However, the reporting of other aspects of research conduct (i.e. descriptions of the research question, the sampling strategy, and data collection methods) in mixed methods studies does not appear to have improved over time. Mixed methods research makes an important contribution to health research in general, and could make a more substantial contribution to systematic reviews. Through our careful analysis of the quality of reporting of mixed methods and qualitative-only research, we have identified areas that deserve more attention in the conduct and reporting of mixed methods research.

  15. Including mixed methods research in systematic reviews: Examples from qualitative syntheses in TB and malaria control

    Science.gov (United States)

    2012-01-01

    Background Health policy makers now have access to a greater number and variety of systematic reviews to inform different stages in the policy making process, including reviews of qualitative research. The inclusion of mixed methods studies in systematic reviews is increasing, but these studies pose particular challenges to methods of review. This article examines the quality of the reporting of mixed methods and qualitative-only studies. Methods We used two completed systematic reviews to generate a sample of qualitative studies and mixed method studies in order to make an assessment of how the quality of reporting and rigor of qualitative-only studies compares with that of mixed-methods studies. Results Overall, the reporting of qualitative studies in our sample was consistently better when compared with the reporting of mixed methods studies. We found that mixed methods studies are less likely to provide a description of the research conduct or qualitative data analysis procedures and less likely to be judged credible or provide rich data and thick description compared with standalone qualitative studies. Our time-related analysis shows that for both types of study, papers published since 2003 are more likely to report on the study context, describe analysis procedures, and be judged credible and provide rich data. However, the reporting of other aspects of research conduct (i.e. descriptions of the research question, the sampling strategy, and data collection methods) in mixed methods studies does not appear to have improved over time. Conclusions Mixed methods research makes an important contribution to health research in general, and could make a more substantial contribution to systematic reviews. Through our careful analysis of the quality of reporting of mixed methods and qualitative-only research, we have identified areas that deserve more attention in the conduct and reporting of mixed methods research. PMID:22545681

  16. Information Technology Research Services: Powerful Tools to Keep Up with a Rapidly Moving Field

    Science.gov (United States)

    Hunter, Paul

    2010-01-01

    Marty firms offer Information Technology Research reports, analyst calls, conferences, seminars, tools, leadership development, etc. These entities include Gartner, Forrester Research, IDC, The Burton Group, Society for Information Management, 1nfoTech Research, The Corporate Executive Board, and so on. This talk will cover how a number of such services are being used at the Goddard Space Flight Center to improve our IT management practices, workforce skills, approach to innovation, and service delivery. These tools and services are used across the workforce, from the executive leadership to the IT worker. The presentation will cover the types of services each vendor provides and their primary engagement model. The use of these services at other NASA Centers and Headquarters will be included. In addition, I will explain how two of these services are available now to the entire NASA IT workforce through enterprise-wide subscriptions.

  17. Self-Report Dietary Assessment Tools Used in Canadian Research: A Scoping Review.

    Science.gov (United States)

    Kirkpatrick, Sharon I; Vanderlee, Lana; Raffoul, Amanda; Stapleton, Jackie; Csizmadi, Ilona; Boucher, Beatrice A; Massarelli, Isabelle; Rondeau, Isabelle; Robson, Paula J

    2017-03-01

    Choosing the most appropriate dietary assessment tool for a study can be a challenge. Through a scoping review, we characterized self-report tools used to assess diet in Canada to identify patterns in tool use and to inform strategies to strengthen nutrition research. The research databases Medline, PubMed, PsycINFO, and CINAHL were used to identify Canadian studies published from 2009 to 2014 that included a self-report assessment of dietary intake. The search elicited 2358 records that were screened to identify those that reported on self-report dietary intake among nonclinical, non-Aboriginal adult populations. A pool of 189 articles (reflecting 92 studies) was examined in-depth to assess the dietary assessment tools used. Food-frequency questionnaires (FFQs) and screeners were used in 64% of studies, whereas food records and 24-h recalls were used in 18% and 14% of studies, respectively. Three studies (3%) used a single question to assess diet, and for 3 studies the tool used was not clear. A variety of distinct FFQs and screeners, including those developed and/or adapted for use in Canada and those developed elsewhere, were used. Some tools were reported to have been evaluated previously in terms of validity or reliability, but details of psychometric testing were often lacking. Energy and fat were the most commonly studied, reported by 42% and 39% of studies, respectively. For ∼20% of studies, dietary data were used to assess dietary quality or patterns, whereas close to half assessed ≤5 dietary components. A variety of dietary assessment tools are used in Canadian research. Strategies to improve the application of current evidence on best practices in dietary assessment have the potential to support a stronger and more cohesive literature on diet and health. Such strategies could benefit from national and global collaboration. © 2017 American Society for Nutrition.

  18. The GATO gene annotation tool for research laboratories

    Directory of Open Access Journals (Sweden)

    A. Fujita

    2005-11-01

    Full Text Available Large-scale genome projects have generated a rapidly increasing number of DNA sequences. Therefore, development of computational methods to rapidly analyze these sequences is essential for progress in genomic research. Here we present an automatic annotation system for preliminary analysis of DNA sequences. The gene annotation tool (GATO is a Bioinformatics pipeline designed to facilitate routine functional annotation and easy access to annotated genes. It was designed in view of the frequent need of genomic researchers to access data pertaining to a common set of genes. In the GATO system, annotation is generated by querying some of the Web-accessible resources and the information is stored in a local database, which keeps a record of all previous annotation results. GATO may be accessed from everywhere through the internet or may be run locally if a large number of sequences are going to be annotated. It is implemented in PHP and Perl and may be run on any suitable Web server. Usually, installation and application of annotation systems require experience and are time consuming, but GATO is simple and practical, allowing anyone with basic skills in informatics to access it without any special training. GATO can be downloaded at [http://mariwork.iq.usp.br/gato/]. Minimum computer free space required is 2 MB.

  19. The GATO gene annotation tool for research laboratories.

    Science.gov (United States)

    Fujita, A; Massirer, K B; Durham, A M; Ferreira, C E; Sogayar, M C

    2005-11-01

    Large-scale genome projects have generated a rapidly increasing number of DNA sequences. Therefore, development of computational methods to rapidly analyze these sequences is essential for progress in genomic research. Here we present an automatic annotation system for preliminary analysis of DNA sequences. The gene annotation tool (GATO) is a Bioinformatics pipeline designed to facilitate routine functional annotation and easy access to annotated genes. It was designed in view of the frequent need of genomic researchers to access data pertaining to a common set of genes. In the GATO system, annotation is generated by querying some of the Web-accessible resources and the information is stored in a local database, which keeps a record of all previous annotation results. GATO may be accessed from everywhere through the internet or may be run locally if a large number of sequences are going to be annotated. It is implemented in PHP and Perl and may be run on any suitable Web server. Usually, installation and application of annotation systems require experience and are time consuming, but GATO is simple and practical, allowing anyone with basic skills in informatics to access it without any special training. GATO can be downloaded at [http://mariwork.iq.usp.br/gato/]. Minimum computer free space required is 2 MB.

  20. `INCLUDING' Partnerships to Build Authentic Research Into K-12 Science Education

    Science.gov (United States)

    Turrin, M.; Lev, E.; Newton, R.; Xu, C.

    2017-12-01

    Opportunities for authentic research experiences have been shown effective for recruiting and retaining students in STEM fields. Meaningful research experiences entail significant time in project design, modeling ethical practice, providing training, instruction, and ongoing guidance. We propose that in order to be sustainable, a new instructional paradigm is needed, one that shifts from being top-weighted in instruction to a distributed weight model. This model relies on partnerships where everyone has buy-in and reaps rewards, establishing broadened networks for support, and adjusting the mentoring model. We use our successful Secondary School Field Research Program as a model for this new paradigm. For over a decade this program has provided authentic geoscience field research for an expanding group of predominantly inner city high school youth from communities underrepresented in the sciences. The program has shifted the balance with returning participants now serving as undergraduate mentors for the high school student `researchers', providing much of the ongoing training, instruction, guidance and feedback needed. But in order to be sustainable and impactful we need to broaden our base. A recent NSF-INCLUDES pilot project has allowed us to expand this model, linking schools, informal education non-profits, other academic institutions, community partners and private funding agencies into geographically organized `clusters'. Starting with a tiered mentoring model with scientists as consultants, teachers as team members, undergraduates as team leaders and high school students as researchers, each cluster will customize its program to reflect the needs and strengths of the team. To be successful each organization must identify how the program fits their organizational goals, the resources they can contribute and what they need back. Widening the partnership base spreads institutional commitments for research scientists, research locations and lab space

  1. e-research: Changes and challenges in the use of digital tools in primary care research

    DEFF Research Database (Denmark)

    Bruun Larsen, Lars; Skonnord, Trygve; Gjelstad, Svein

    Objectives This workshop aims to present examples of digital tools and technology that can improve the quality of clinical research. The presenters and participants will discuss both possibilities and pitfalls. Background Electronic surveys and other digital tools can ease data collection...... challenges within the field. To secure a high response rate, you need to follow up manually or use another application. There are also practical and ethical problems, and the data security for sensitive data have to be followed carefully. Session content Oral presentations about some technological...

  2. Research and technology management in the electricity industry methods, tools and case studies

    CERN Document Server

    Daim, Tugrul; Kim, Jisun

    2013-01-01

    Technologies such as renewable energy alternatives including wind, solar and biomass, storage technologies and electric engines are creating a different landscape for the  electricity industry. Using sources and ideas from technologies such as renewable energy alternatives, Research and Technology Management in the Electricity Industry explores a different landscape for this industry and applies it to the electric industry supported by real industry cases. Divided into three sections, Research and Technology Management in the Electricity Industry introduces a range of  methods and tools includ

  3. 76 FR 13665 - Cambridge Tool & Die, Including On-Site Leased Workers From Action Total Staffing, Cambridge, OH...

    Science.gov (United States)

    2011-03-14

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,605] Cambridge Tool & Die... Eligibility To Apply for Worker Adjustment Assistance In accordance with Section 223 of the Trade Act of 1974... of Cambridge Tool & Die, Cambridge, Ohio. The workers are engaged in the production of plastic...

  4. Development of a journal recommendation tool based upon co-citation analysis of journals cited in Wageningen UR research articles

    NARCIS (Netherlands)

    Veller, van M.G.P.; Gerritsma, W.

    2015-01-01

    Wageningen UR Library has developed a tool based upon co-citation analysis to recommend alternative journals to researchers for a journal they look up in the tool. The journal recommendations can be tuned in such a way to include citation preferences for each of the five science groups that comprise

  5. Rethinking the Role of Information Technology-Based Research Tools in Students' Development of Scientific Literacy

    Science.gov (United States)

    van Eijck, Michiel; Roth, Wolff-Michael

    2007-06-01

    Given the central place IT-based research tools take in scientific research, the marginal role such tools currently play in science curricula is dissatisfying from the perspective of making students scientifically literate. To appropriately frame the role of IT-based research tools in science curricula, we propose a framework that is developed to understand the use of tools in human activity, namely cultural-historical activity theory (CHAT). Accordingly, IT-based research tools constitute central moments of scientific research activity and neither can be seen apart from its objectives, nor can it be considered apart from the cultural-historical determined forms of activity (praxis) in which human subjects participate. Based on empirical data involving students participating in research activity, we point out how an appropriate account of IT-based research tools involves subjects' use of tools with respect to the objectives of research activity and the contribution to the praxis of research. We propose to reconceptualize the role of IT-based research tools as contributing to scientific literacy if students apply these tools with respect to the objectives of the research activity and contribute to praxis of research by evaluating and modifying the application of these tools. We conclude this paper by sketching the educational implications of this reconceptualized role of IT-based research tools.

  6. IT Tools for Teachers and Scientists, Created by Undergraduate Researchers

    Science.gov (United States)

    Millar, A. Z.; Perry, S.

    2007-12-01

    Interns in the Southern California Earthquake Center/Undergraduate Studies in Earthquake Information Technology (SCEC/UseIT) program conduct computer science research for the benefit of earthquake scientists and have created products in growing use within the SCEC education and research communities. SCEC/UseIT comprises some twenty undergraduates who combine their varied talents and academic backgrounds to achieve a Grand Challenge that is formulated around needs of SCEC scientists and educators and that reflects the value SCEC places on the integration of computer science and the geosciences. In meeting the challenge, students learn to work on multidisciplinary teams and to tackle complex problems with no guaranteed solutions. Meantime, their efforts bring fresh perspectives and insight to the professionals with whom they collaborate, and consistently produces innovative, useful tools for research and education. The 2007 Grand Challenge was to design and prototype serious games to communicate important earthquake science concepts. Interns broke themselves into four game teams, the Educational Game, the Training Game, the Mitigation Game and the Decision-Making Game, and created four diverse games with topics from elementary plate tectonics to earthquake risk mitigation, with intended players ranging from elementary students to city planners. The games were designed to be versatile, to accommodate variation in the knowledge base of the player; and extensible, to accommodate future additions. The games are played on a web browser or from within SCEC-VDO (Virtual Display of Objects). SCEC-VDO, also engineered by UseIT interns, is a 4D, interactive, visualization software that enables integration and exploration of datasets and models such as faults, earthquake hypocenters and ruptures, digital elevation models, satellite imagery, global isochrons, and earthquake prediction schemes. SCEC-VDO enables the user to create animated movies during a session, and is now part

  7. Microplasmas for chemical analysis: analytical tools or research toys?

    International Nuclear Information System (INIS)

    Karanassios, Vassili

    2004-01-01

    An overview of the activities of the research groups that have been involved in fabrication, development and characterization of microplasmas for chemical analysis over the last few years is presented. Microplasmas covered include: miniature inductively coupled plasmas (ICPs); capacitively coupled plasmas (CCPs); microwave-induced plasmas (MIPs); a dielectric barrier discharge (DBD); microhollow cathode discharge (MCHD) or microstructure electrode (MSE) discharges, other microglow discharges (such as those formed between 'liquid' electrodes); microplasmas formed in micrometer-diameter capillary tubes for gas chromatography (GC) or high-performance liquid chromatography (HPLC) applications, and a stabilized capacitive plasma (SCP) for GC applications. Sample introduction into microplasmas, in particular, into a microplasma device (MPD), battery operation of a MPD and of a mini- in-torch vaporization (ITV) microsample introduction system for MPDs, and questions of microplasma portability for use on site (e.g., in the field) are also briefly addressed using examples of current research. To emphasize the significance of sample introduction into microplasmas, some previously unpublished results from the author's laboratory have also been included. And an overall assessment of the state-of-the-art of analytical microplasma research is provided

  8. Facebook: an effective tool for participant retention in longitudinal research.

    Science.gov (United States)

    Mychasiuk, R; Benzies, K

    2012-09-01

    Facebook is currently one of the world's most visited websites, and home to millions of users who access their accounts on a regular basis. Owing to the website's ease of accessibility and free service, demographic characteristics of users span all domains. As such, Facebook may be a valuable tool for locating and communicating with participants in longitudinal research studies. This article outlines the benefit gained in a longitudinal follow-up study, of an intervention programme for at-risk families, through the use of Facebook as a search engine. Using Facebook as a resource, we were able to locate 19 participants that were otherwise 'lost' to follow-up, decreasing attrition in our study by 16%. Additionally, analysis indicated that hard-to-reach participants located with Facebook differed significantly on measures of receptive language and self-esteem when compared to their easier-to-locate counterparts. These results suggest that Facebook is an effective means of improving participant retention in a longitudinal intervention study and may help improve study validity by reaching participants that contribute differing results. © 2011 Blackwell Publishing Ltd.

  9. Research tools application for female fashion underwear comfort assesment

    Directory of Open Access Journals (Sweden)

    Andreia Salvan Pagnan

    2016-06-01

    Full Text Available Within the women's clothing of the universe's underwear were long an insignificant plan with regard to the development of new textile materials, shapes and colors. The panties that had been known as breeches or long underwear only became a necessity around the twentieth century with the vaporous dresses Christian Dior in the 50 Technological advances in the textile industry brought spandex created by the American laboratory DuPont's better known as the lycra. The elasticity of the fabric gave comfort to women's lingerie, passing this attribute to be considered as a quality factor in lingeries. To understand the desires of the users a qualitative research was conducted with women 18-45 years collecting opinions on the perceived comfort of already existing models compared to a new one be launched. Through the Quality Function Deployment Tool (QFD, or Quality Function Deployment, the data obtained from users of the answers given an interpretation which is to prioritize targets for the development of a based product on analyzes of desired characteristics which are converted into attributes technicians.

  10. CRISPR/Cas9: A tool for immunological research.

    Science.gov (United States)

    Hochheiser, Katharina; Kueh, Andrew J; Gebhardt, Thomas; Herold, Marco J

    2018-02-07

    The CRISPR/Cas9-system was originally identified as part of the adaptive immune system in bacteria and has since been adapted for the genetic manipulation of eukaryotic cells. The technique is of particular value for biomedical sciences, as it enables the genetic manipulation of cell lines and primary cells as well as whole organisms with unprecedented ease and efficiency. Furthermore, the CRISPR/Cas9-technology has the potential for future therapeutic applications in the clinic. Here, we discuss the use of CRISPR/Cas9 for the genetic modification of haematopoietic cells and the generation of mouse models for immunological research. Additionally, we explain how the technique can be applied as a screening-tool to identify genes involved in different immunological processes. Moreover, we will talk about recent extensions of using the CRISPR/Cas9 technology, such as a transcriptional activator or repressor. Finally, we discuss the first clinical trials that use CRISPR/Cas9 and discuss potential future applications. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Tissue Microarray: A rapidly evolving diagnostic and research tool

    Science.gov (United States)

    Jawhar, Nazar M.T.

    2009-01-01

    Tissue microarray is a recent innovation in the field of pathology. A microarray contains many small representative tissue samples from hundreds of different cases assembled on a single histologic slide, and therefore allows high throughput analysis of multiple specimens at the same time. Tissue microarrays are paraffin blocks produced by extracting cylindrical tissue cores from different paraffin donor blocks and re-embedding these into a single recipient (microarray) block at defined array coordinates. Using this technique, up to 1000 or more tissue samples can be arrayed into a single paraffin block. It can permit simultaneous analysis of molecular targets at the DNA, mRNA, and protein levels under identical, standardized conditions on a single glass slide, and also provide maximal preservation and use of limited and irreplaceable archival tissue samples. This versatile technique, in which data analysis is automated facilitates retrospective and prospective human tissue studies. It is a practical and effective tool for high-throughput molecular analysis of tissues that is helping to identify new diagnostic and prognostic markers and targets in human cancers, and has a range of potential applications in basic research, prognostic oncology and drug discovery. This article summarizes the technical aspects of tissue microarray construction and sectioning, advantages, application, and limitations. PMID:19318744

  12. Fish as research tools: alternatives to in vivo experiments.

    Science.gov (United States)

    Schaeck, Marlien; Van den Broeck, Wim; Hermans, Katleen; Decostere, Annemie

    2013-07-01

    The use of fish in scientific research is increasing worldwide, due to both the rapid expansion of the fish farming industry and growing awareness of questions concerning the humane use of mammalian models in basic research and chemical testing. As fish are lower on the evolutionary scale than mammals, they are considered to be less sentient. Fish models are providing researchers, and those concerned with animal welfare, with opportunities for adhering to the Three Rs principles of refinement, reduction and replacement. However, it should be kept in mind that fish should also be covered by the principles of the Three Rs. Indeed, various studies have shown that fish are capable of nociception, and of experiencing pain in a manner analogous to that in mammals. Thus, emphasis needs to be placed on the development of alternatives that replace, as much as possible, the use of all living vertebrate animals, including fish. This review gives the first comprehensive and critical overview of the existing alternatives for live fish experimental studies. The alternative methods described range from cell and tissue cultures, organ and perfusion models, and embryonic models, to in silico computer and mathematical models. This article aspires to guide scientists in the adoption of the correct alternative methods in their research, and, whenever possible, to reduce the use of live fish. 2013 FRAME.

  13. Simple Tools to Facilitate Project Management of a Nursing Research Project.

    Science.gov (United States)

    Aycock, Dawn M; Clark, Patricia C; Thomas-Seaton, LaTeshia; Lee, Shih-Yu; Moloney, Margaret

    2016-07-01

    Highly organized project management facilitates rigorous study implementation. Research involves gathering large amounts of information that can be overwhelming when organizational strategies are not used. We describe a variety of project management and organizational tools used in different studies that may be particularly useful for novice researchers. The studies were a multisite study of caregivers of stroke survivors, an Internet-based diary study of women with migraines, and a pilot study testing a sleep intervention in mothers of low-birth-weight infants. Project management tools were used to facilitate enrollment, data collection, and access to results. The tools included protocol and eligibility checklists, event calendars, screening and enrollment logs, instrument scoring tables, and data summary sheets. These tools created efficiency, promoted a positive image, minimized errors, and provided researchers with a sense of control. For the studies described, there were no protocol violations, there were minimal missing data, and the integrity of data collection was maintained. © The Author(s) 2016.

  14. NASA System-Level Design, Analysis and Simulation Tools Research on NextGen

    Science.gov (United States)

    Bardina, Jorge

    2011-01-01

    A review of the research accomplished in 2009 in the System-Level Design, Analysis and Simulation Tools (SLDAST) of the NASA's Airspace Systems Program is presented. This research thrust focuses on the integrated system-level assessment of component level innovations, concepts and technologies of the Next Generation Air Traffic System (NextGen) under research in the ASP program to enable the development of revolutionary improvements and modernization of the National Airspace System. The review includes the accomplishments on baseline research and the advancements on design studies and system-level assessment, including the cluster analysis as an annualization standard of the air traffic in the U.S. National Airspace, and the ACES-Air MIDAS integration for human-in-the-loop analyzes within the NAS air traffic simulation.

  15. Chemical countermeasures: Dispersants overview of dispersant use (including application) and research issues

    International Nuclear Information System (INIS)

    Butler, J.N.

    1992-01-01

    I will attempt in twenty minutes to summarize the state of research on oil spill dispersants as I perceive it. The expertise I bring to this task includes 20 years of experience with the fate and effects of petroleum in the marine environment, including participation in the 1973 and 1981 NRC studies and three years as chairman of the NRC committee on oil spill dispersants. I More recently I served on a committee of the International Maritime Organization which reviewed the open-quotes Impact of oil and related chemicals and wastes on the marine environment.close quotes That report will be published this year. However, my statements in this paper are not made as a representative of either NRC or IMO. They are my own interpretation of scientific literature cited in the above reviews. Dispersants are chemical formulations, which include surface active agents, designed to decrease the interfacial tension between oil and water. Because the first attempts to disperse oil on a large scale, at the Torrey Canyon spill of 1967, used highly toxic degreasing agents, dispersants have an undeserved reputation for toxicity. In fact, for twenty years dispersant formulations have been developed with an emphasis on reducing their toxicity to marine life. The dispersal of oil in water has been documented in the laboratory by dozens of papers (see references in NRC 1989, pp 70-79), and in the field by dozens of studies (NRC 1989, pp 165- 193). The toxicity of commercial dispersant formulations (NRC 1989, pp 81-123) and dispersed oil (NRC 1989, pp 123-147) has been tested on a wide variety of marine organisms ranging from algae to salmonid fishes. The NRC review has been updated by the IMO/GESAMP (1992) study, but the conclusions remain unchanged

  16. An action research approach to facilitating the adoption of a foot health assessment tool in India.

    Science.gov (United States)

    Harrison-Blount, Michael; Cullen, Michelle; Nester, Christopher J; Williams, Anita E

    2015-01-01

    India has a diabetes population that is growing and alongside this, the incidence of limb threatening foot problems is increasing. Foot health care provision does not yet meet this demand. In one locality in India, clinicians had an unstructured approach to foot health assessments resulting in poor adoption of evidence based guidelines from the West and a persistence of serious foot complications. There was the perception that existing assessment tools did not take into account the local cultural, organizational and professional needs and there was a lack of ownership of any potential solution to the problem. Therefore, the aim of this work was to facilitate the ownership and development of a foot health assessment tool for use in the Indian context. In order to achieve this an action research approach was chosen. Participants were facilitated through the action and implementation phases of the action research cycle by the researchers. The action phase included generating a list of potential items for inclusion in the tool from a review of the literature to provide an evidence based foundation for the foot health assessment tool. A modified Delphi method was used to further refine the contents of the tool. Members of the Delphi Panel (n = 8) were experts in their field of medicine and experts in delivering health care within services in India. The outcome of the study was the adoption of a locally developed foot health assessment tool (Salford Indian Foot Health Assessment Tool, SIFT). It contains thirteen sections, which reflect the risk factors identified for assessing foot health agreed by the participants to fit the Indian context. The SIFT is supported with evidence based guidelines from the West and a training program was delivered by the researchers in order to support its implementation into clinical practice. An action research approach has facilitated the development and implementation of a locally created and owned foot health assessment tool. This

  17. Modelling as an indispensible research tool in the information society.

    Science.gov (United States)

    Bouma, Johan

    2016-04-01

    realize the described paradigm shift, that will provide meaning to abstract and often misused terms like inter- and trandisciplinarity, fundamental changes are needed in the way the research process is organized, including its evaluation..

  18. A new research tool for hybrid Bayesian networks using script language

    Science.gov (United States)

    Sun, Wei; Park, Cheol Young; Carvalho, Rommel

    2011-06-01

    While continuous variables become more and more inevitable in Bayesian networks for modeling real-life applications in complex systems, there are not much software tools to support it. Popular commercial Bayesian network tools such as Hugin, and Netica etc., are either expensive or have to discretize continuous variables. In addition, some free programs existing in the literature, commonly known as BNT, GeNie/SMILE, etc, have their own advantages and disadvantages respectively. In this paper, we introduce a newly developed Java tool for model construction and inference for hybrid Bayesian networks. Via the representation power of the script language, this tool can build the hybrid model automatically based on a well defined string that follows the specific grammars. Furthermore, it implements several inference algorithms capable to accommodate hybrid Bayesian networks, including Junction Tree algorithm (JT) for conditional linear Gaussian model (CLG), and Direct Message Passing (DMP) for general hybrid Bayesian networks with CLG structure. We believe this tool will be useful for researchers in the field.

  19. New evaluation tool now available to assess research quality | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    25 avr. 2016 ... IDRC supports Strategic Evaluation on Research Excellence, a three-phase project that aims to define and articulate what research excellence means in a ... Read our position paper: Research Quality Plus (RQ+) A Holistic Approach to Evaluating Research (Available in English, French and Spanish).

  20. Korea's Contribution to Radiological Research Included in Science Citation Index Expanded, 1986-2010

    International Nuclear Information System (INIS)

    Ku, You Jin; Yoon, Dae Young; Lim, Kyoung Ja; Baek, Sora; Seo, Young Lan; Yun, Eun Joo; Choi, Chul Soon; Bae, Sang Hoon; Lee, Hyun; Ju, Young Su

    2012-01-01

    To evaluate scientific papers published by Korean radiologists in the Science Citation Index Expanded (SCIE) radiology journals, between 1986 and 2010. The Institute for Scientific Information Web of Knowledge-Web of Science (SCIE) database was searched for all articles published by Korean radiologists, in SCIE radiology journals, between 1986 and 2010. We performed the analysis by typing 'Korea' and 'radiol' in the address section and selecting the subject area of 'Radiology, Nuclear Medicine, and Medical Imaging' with the use of the general search function of the software. Analyzed parameters included the total number of publications, document types, journals, and institutions. In addition, we analyzed where Korea ranks, compared to other countries, in terms of the number of published articles. All these data were analyzed according to five time periods: 1986-1990, 1991-1995, 1996-2000, 2001-2005, and 2006-2010. Overall, 4974 papers were published by Korean radiologists, in 99 different SCIE journals, between 1986 and 2010, of which 4237 (85.2%) were article-type papers. Of the total 115395 articles, worldwide, published in radiology journals, Korea's share was 3.7%, with an upward trend over time (p < 0.005). The journal with the highest number of articles was the American Journal of Roentgenology (n 565, 13.3%). The institution which produced the highest number of publications was Seoul National University (n = 932, 22.0%). The number of scientific articles published by Korean radiologists in the SCIE radiology journals has increased significantly between 1986 and 2010. Korea was ranked 4th among countries contributing to radiology research during the last 5 years.

  1. Women and tobacco: a call for including gender in tobacco control research, policy and practice.

    Science.gov (United States)

    Amos, Amanda; Greaves, Lorraine; Nichter, Mimi; Bloch, Michele

    2012-03-01

    Female smoking is predicted to double between 2005 and 2025. There have been numerous calls for action on women's tobacco use over the past two decades. In the present work, evidence about female tobacco use, progress, challenges and ways forward for developing gendered tobacco control is reviewed. Literature on girls, women and tobacco was reviewed to identify trends and determinants of tobacco use and exposure, the application of gender analysis, tobacco marketing, the impact of tobacco control on girls and women and ways to address these issues particularly in low-income and middle-income countries. Global female tobacco use is increasingly complex, involving diverse products and factors including tobacco marketing, globalisation and changes in women's status. In high-income countries female smoking is declining but is increasingly concentrated among disadvantaged women. In low-income and middle-income countries the pattern is more complex; in several regions the gap between girls' and boys' smoking is narrow. Gendered analyses and approaches to tobacco control are uncommon, especially in low-income and middle-income countries. Tobacco control has remained largely gender blind, with little recognition of the importance of understanding the context and challenges of girl's and women's smoking and secondhand smoke exposure. There has been little integration of gender considerations in research, policy and programmes. The present work makes a case for gender and diversity analyses in tobacco control to reflect and identify intersecting factors affecting women's tobacco use. This will help animate the WHO Framework Convention on Tobacco Control's concern for gender specificity and women's leadership, and reduce the impact of tobacco on women.

  2. Endothelial cell cultures as a tool in biomaterial research

    NARCIS (Netherlands)

    Kirkpatrick, CJ; Otto, M; van Kooten, T; Krump, [No Value; Kriegsmann, J; Bittinger, F

    1999-01-01

    Progress in biocompatibility and tissue engineering would today be inconceivable without the aid of in vitro techniques. Endothelial cell cultures represent a valuable tool not just in haemocompatibility testing, but also in the concept of designing hybrid organs. In the past endothelial cells (EC)

  3. Design research in statistics education : on symbolizing and computer tools

    NARCIS (Netherlands)

    Bakker, A.

    2004-01-01

    The present knowledge society requires statistical literacy-the ability to interpret, critically evaluate, and communicate about statistical information and messages (Gal, 2002). However, research shows that students generally do not gain satisfactory statistical understanding. The research

  4. Research reactors: a tool for science and medicine

    International Nuclear Information System (INIS)

    Ordonez, Juan

    2001-01-01

    The types and uses of research reactors are reviewed. After an analysis of the world situation, the demand of new research reactors of about 20 MW is foreseen. The experience and competitiveness of INVAP S.E. as designer and constructor of research reactors is outlined and the general specifications of the reactors designed by INVAP for Egypt and Australia are given

  5. Tools for Monitoring Social Media: A Marketing Research Project

    Science.gov (United States)

    Veeck, Ann; Hoger, Beth

    2014-01-01

    Knowledge of how to effectively monitor social media is an increasingly valued marketing research skill. This study tests an approach for adding social media content to an undergraduate marketing research class team project. The revised project maintains the expected objectives and parameters of a traditional research project, while integrating…

  6. "Mythbusters": A Tool for Teaching Research Methods in Psychology

    Science.gov (United States)

    Burkley, Edward; Burkley, Melissa

    2009-01-01

    "Mythbusters" uses multiple research methods to test interesting topics, offering research methods students an entertaining review of course material. To test the effectiveness of "Mythbusters" clips in a psychology research methods course, we systematically selected and showed 4 clips. Students answered questions about the clips, offered their…

  7. Setting global research priorities for developmental disabilities, including intellectual disabilities and autism.

    Science.gov (United States)

    Tomlinson, M; Yasamy, M T; Emerson, E; Officer, A; Richler, D; Saxena, S

    2014-12-01

    The prevalence of intellectual disabilities (ID) has been estimated at 10.4/1000 worldwide with higher rates among children and adolescents in lower income countries. The objective of this paper is to address research priorities for development disabilities, notably ID and autism, at the global level and to propose the more rational use of scarce funds in addressing this under-investigated area. An expert group was identified and invited to systematically list and score research questions. They applied the priority setting methodology of the Child Health and Nutrition Research Initiative (CHNRI) to generate research questions and to evaluate them using a set of five criteria: answerability, feasibility, applicability and impact, support within the context and equity. The results of this process clearly indicated that the important priorities for future research related to the need for effective and efficient approaches to early intervention, empowerment of families supporting a person with developmental disability and to address preventable causes of poor health in people with ID and autism. For the public health and other systems to become more effective in delivering appropriate support to persons with developmental disabilities, greater (and more targeted) investment in research is required to produce evidence of what works consistent with international human rights standards. © 2014 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  8. Research Game: an innovative educational tool for teachers and students

    Directory of Open Access Journals (Sweden)

    Franca Sangiorgio

    2014-12-01

    Full Text Available This contribution describes ‘Research Game’, a game produced in a Lifelong Learning Programme-Comenius Project (The European Scientific Research Game which aims at motivating secondary school students through the experience of the excitement of scientific research. The project proposes practical and didactic works which combine theoretical activities with ICT in order to introduce students to the scientific research. Students collaborated internationally across Europe, to build hypotheses, carry out research, test the validity of their hypothesis and finalize a theory based on their findings. On the project platform (www.researchgame.eu/platform teachers and students registered, created a team, interacted on a forum space, played and learned science in a new innovative way. Here, the students shared their research findings with other groups of all Europe; finally competed online playing a serious game and showing to be able to apply the scientific method.

  9. A Computer Vision Tool For Use in Horticultural Research

    OpenAIRE

    Thoreson, Marcus Alexander

    2017-01-01

    With growing concerns about global food supply and environmental impacts of modern agriculture, we are seeing an increased demand for more horticultural research. While research into plant genetics has seen an increased throughput from recent technological advancements, plant phenotypic research throughput has lagged behind. Improvements in open-source image processing software and image capture hardware have created an opportunity for the development of more competitively-priced, faster data...

  10. What Can We Learn from Bioactivity Data? Chemoinformatics Tools and Applications in Chemical Biology Research.

    Science.gov (United States)

    Humbeck, Lina; Koch, Oliver

    2017-01-20

    The ever increasing bioactivity data that are produced nowadays allow exhaustive data mining and knowledge discovery approaches that change chemical biology research. A wealth of chemoinformatics tools, web services, and applications therefore exists that supports a careful evaluation and analysis of experimental data to draw conclusions that can influence the further development of chemical probes and potential lead structures. This review focuses on open-source approaches that can be handled by scientists who are not familiar with computational methods having no expert knowledge in chemoinformatics and modeling. Our aim is to present an easily manageable toolbox for support of every day laboratory work. This includes, among other things, the available bioactivity and related molecule databases as well as tools to handle and analyze in-house data.

  11. Flood Risk Research and Warning Tools at the European Scale

    NARCIS (Netherlands)

    Roo, A.P.J. de; Thielen, J.; Feyen, L.; Burek, P.; Salamon, P.

    2012-01-01

    The floods in the rivers Meuse and Rhine in 1993 and 1995 made the European Commission realize that also at Commission level further research on floods – especially in transboundary river catchments - was necessary. This led to the start of a dedicated research project on floods at the European

  12. Systems Engineering-Based Tool for Identifying Critical Research Systems

    Science.gov (United States)

    Abbott, Rodman P.; Stracener, Jerrell

    2016-01-01

    This study investigates the relationship between the designated research project system independent variables of Labor, Travel, Equipment, and Contract total annual costs and the dependent variables of both the associated matching research project total annual academic publication output and thesis/dissertation number output. The Mahalanobis…

  13. Process models as tools in forestry research and management

    Science.gov (United States)

    Kurt Johnsen; Lisa Samuelson; Robert Teskey; Steve McNulty; Tom Fox

    2001-01-01

    Forest process models are mathematical representations of biological systems that incorporate our understanding of physiological and ecological mechanisms into predictive algorithms. These models were originally designed and used for research purposes, but are being developed for use in practical forest management. Process models designed for research...

  14. Propositional Analysis: A Tool for Library and Information Science Research.

    Science.gov (United States)

    Allen, Bryce

    1989-01-01

    Reviews the use of propositional analysis in library and information science research. Evidence that different analysts produce similar judgments about texts and use the method consistently over time is presented, and it is concluded that propositional analysis is a reliable and valid research method. An example of an analysis is appended. (32…

  15. Critical Practical Analogy: A Research Tool for Reflecting and Making

    Directory of Open Access Journals (Sweden)

    Dino Alfier

    2011-01-01

    Full Text Available What contribution can visual art practice bring to interdisciplinary research? And how to give an account of practice-led research that acknowledges the need for interdisciplinary intelligibility? I consider these two questions by reflecting on the methodology--which I call "critical practical analogy" (CPA--that I have developed while investigating the metaethical implications of French philosopher Simone Weil's notion of attention, during my practice-led PhD. In order to address the first question, I consider as a case study a research art project that employs CPA, and I explain how CPA proved instrumental in overcoming the impasse that I reached by purely theoretical investigation of Weil's discourse on attention and how it opened a distinctly artistic way forward in my research. In order to address the second question, I consider a problem posed by the interdisciplinary nature of my research (covering art and philosophy. I show how, through the application of CPA to the case study, I articulated an exegesis of my research that was intelligible across these two heterogeneous fields of investigation. In conclusion, I give some reasons for my hope that CPA may possess some heuristic and exegetical applicability in practice-led interdisciplinary research beyond my own research.

  16. Somatic Sensitivity and Reflexivity as Validity Tools in Qualitative Research

    Science.gov (United States)

    Green, Jill

    2015-01-01

    Validity is a key concept in qualitative educational research. Yet, it is often not addressed in methodological writing about dance. This essay explores validity in a postmodern world of diverse approaches to scholarship, by looking at the changing face of validity in educational qualitative research and at how new understandings of the concept…

  17. A New Tool for Identifying Research Standards and Evaluating Research Performance

    Science.gov (United States)

    Bacon, Donald R.; Paul, Pallab; Stewart, Kim A.; Mukhopadhyay, Kausiki

    2012-01-01

    Much has been written about the evaluation of faculty research productivity in promotion and tenure decisions, including many articles that seek to determine the rank of various marketing journals. Yet how faculty evaluators combine journal quality, quantity, and author contribution to form judgments of a scholar's performance is unclear. A…

  18. The virtual supermarket: an innovative research tool to study consumer food purchasing behaviour.

    Science.gov (United States)

    Waterlander, Wilma E; Scarpa, Michael; Lentz, Daisy; Steenhuis, Ingrid H M

    2011-07-25

    and is freely available for academic use. The unique features of the tool include the fact that it enables researchers to easily modify research conditions and in this way study different types of interventions in a retail environment without a complex implementation process. Finally, it also maintains researcher independence and avoids conflicts of interest that may arise from industry collaboration.

  19. The virtual supermarket: An innovative research tool to study consumer food purchasing behaviour

    Directory of Open Access Journals (Sweden)

    Steenhuis Ingrid HM

    2011-07-01

    purchasing behaviour. The application can be obtained via an URL and is freely available for academic use. The unique features of the tool include the fact that it enables researchers to easily modify research conditions and in this way study different types of interventions in a retail environment without a complex implementation process. Finally, it also maintains researcher independence and avoids conflicts of interest that may arise from industry collaboration.

  20. Satellite telemetry: A new tool for wildlife research and management

    Science.gov (United States)

    Fancy, Steven G.; Pank, Larry F.; Douglas, David C.; Curby, Catherine H.; Garner, Gerald W.; Amstrup, Steven C.; Regelin, Wayne L.

    1998-01-01

    operation, the UHF (ultra-high frequency) signal failed on three of 32 caribou transmitters and 10 of 36 polar bear transmitters.A geographic information system (GIS) incorporating other databases (e.g., land cover, elevation, slope, aspect, hydrology, ice distribution) was used to analyze and display detailed locational and behavioral data collected via satellite. Examples of GIS applications to research projects using satellite telemetry and examples of detailed movement patterns of caribou and polar bears are presented. This report includes documentation for computer software packages for processing Argos data and presents developments, as of March 1987, in transmitter design, data retrieval using a local user terminal, computer software, and sensor development and calibration.

  1. Lowering the Barrier to Reproducible Research by Publishing Provenance from Common Analytical Tools

    Science.gov (United States)

    Jones, M. B.; Slaughter, P.; Walker, L.; Jones, C. S.; Missier, P.; Ludäscher, B.; Cao, Y.; McPhillips, T.; Schildhauer, M.

    2015-12-01

    Scientific provenance describes the authenticity, origin, and processing history of research products and promotes scientific transparency by detailing the steps in computational workflows that produce derived products. These products include papers, findings, input data, software products to perform computations, and derived data and visualizations. The geosciences community values this type of information, and, at least theoretically, strives to base conclusions on computationally replicable findings. In practice, capturing detailed provenance is laborious and thus has been a low priority; beyond a lab notebook describing methods and results, few researchers capture and preserve detailed records of scientific provenance. We have built tools for capturing and publishing provenance that integrate into analytical environments that are in widespread use by geoscientists (R and Matlab). These tools lower the barrier to provenance generation by automating capture of critical information as researchers prepare data for analysis, develop, test, and execute models, and create visualizations. The 'recordr' library in R and the `matlab-dataone` library in Matlab provide shared functions to capture provenance with minimal changes to normal working procedures. Researchers can capture both scripted and interactive sessions, tag and manage these executions as they iterate over analyses, and then prune and publish provenance metadata and derived products to the DataONE federation of archival repositories. Provenance traces conform to the ProvONE model extension of W3C PROV, enabling interoperability across tools and languages. The capture system supports fine-grained versioning of science products and provenance traces. By assigning global identifiers such as DOIs, reseachers can cite the computational processes used to reach findings. And, finally, DataONE has built a web portal to search, browse, and clearly display provenance relationships between input data, the software

  2. Extending the XNAT archive tool for image and analysis management in ophthalmology research

    Science.gov (United States)

    Wahle, Andreas; Lee, Kyungmoo; Harding, Adam T.; Garvin, Mona K.; Niemeijer, Meindert; Sonka, Milan; Abràmoff, Michael D.

    2013-03-01

    In ophthalmology, various modalities and tests are utilized to obtain vital information on the eye's structure and function. For example, optical coherence tomography (OCT) is utilized to diagnose, screen, and aid treatment of eye diseases like macular degeneration or glaucoma. Such data are complemented by photographic retinal fundus images and functional tests on the visual field. DICOM isn't widely used yet, though, and frequently images are encoded in proprietary formats. The eXtensible Neuroimaging Archive Tool (XNAT) is an open-source NIH-funded framework for research PACS and is in use at the University of Iowa for neurological research applications. Its use for ophthalmology was hence desirable but posed new challenges due to data types thus far not considered and the lack of standardized formats. We developed custom tools for data types not natively recognized by XNAT itself using XNAT's low-level REST API. Vendor-provided tools can be included as necessary to convert proprietary data sets into valid DICOM. Clients can access the data in a standardized format while still retaining the original format if needed by specific analysis tools. With respective project-specific permissions, results like segmentations or quantitative evaluations can be stored as additional resources to previously uploaded datasets. Applications can use our abstract-level Python or C/C++ API to communicate with the XNAT instance. This paper describes concepts and details of the designed upload script templates, which can be customized to the needs of specific projects, and the novel client-side communication API which allows integration into new or existing research applications.

  3. The Use of Bibliometric Data as Tools for University Research Policy.

    Science.gov (United States)

    Moed, H. F.; And Others

    1985-01-01

    A University of Leiden study on the potential use of quantitative, literature-based indicators as tools for monitoring research productivity and establishing research policy, based on the bibliographic productivity of two major faculties, is reported and discussed. (MSE)

  4. The SPARK Tool to prioritise questions for systematic reviews in health policy and systems research: development and initial validation.

    Science.gov (United States)

    Akl, Elie A; Fadlallah, Racha; Ghandour, Lilian; Kdouh, Ola; Langlois, Etienne; Lavis, John N; Schünemann, Holger; El-Jardali, Fadi

    2017-09-04

    Groups or institutions funding or conducting systematic reviews in health policy and systems research (HPSR) should prioritise topics according to the needs of policymakers and stakeholders. The aim of this study was to develop and validate a tool to prioritise questions for systematic reviews in HPSR. We developed the tool following a four-step approach consisting of (1) the definition of the purpose and scope of tool, (2) item generation and reduction, (3) testing for content and face validity, (4) and pilot testing of the tool. The research team involved international experts in HPSR, systematic review methodology and tool development, led by the Center for Systematic Reviews on Health Policy and Systems Research (SPARK). We followed an inclusive approach in determining the final selection of items to allow customisation to the user's needs. The purpose of the SPARK tool was to prioritise questions in HPSR in order to address them in systematic reviews. In the item generation and reduction phase, an extensive literature search yielded 40 relevant articles, which were reviewed by the research team to create a preliminary list of 19 candidate items for inclusion in the tool. As part of testing for content and face validity, input from international experts led to the refining, changing, merging and addition of new items, and to organisation of the tool into two modules. Following pilot testing, we finalised the tool, with 22 items organised in two modules - the first module including 13 items to be rated by policymakers and stakeholders, and the second including 9 items to be rated by systematic review teams. Users can customise the tool to their needs, by omitting items that may not be applicable to their settings. We also developed a user manual that provides guidance on how to use the SPARK tool, along with signaling questions. We have developed and conducted initial validation of the SPARK tool to prioritise questions for systematic reviews in HPSR, along with

  5. Integrating Contemplative Tools into Biomedical Science Education and Research Training Programs

    Directory of Open Access Journals (Sweden)

    Rodney R. Dietert

    2014-01-01

    Full Text Available Academic preparation of science researchers and/or human or veterinary medicine clinicians through the science, technology, engineering, and mathematics (STEM curriculum has usually focused on the students (1 acquiring increased disciplinary expertise, (2 learning needed methodologies and protocols, and (3 expanding their capacity for intense, persistent focus. Such educational training is effective until roadblocks or problems arise via this highly-learned approach. Then, the health science trainee may have few tools available for effective problem solving. Training to achieve flexibility, adaptability, and broadened perspectives using contemplative practices has been rare among biomedical education programs. To address this gap, a Cornell University-based program involving formal biomedical science coursework, and health science workshops has been developed to offer science students, researchers and health professionals a broader array of personal, contemplation-based, problem-solving tools. This STEM educational initiative includes first-person exercises designed to broaden perceptional awareness, decrease emotional drama, and mobilize whole-body strategies for creative problem solving. Self-calibration and journaling are used for students to evaluate the personal utility of each exercise. The educational goals are to increase student self-awareness and self-regulation and to provide trainees with value-added tools for career-long problem solving. Basic elements of this educational initiative are discussed using the framework of the Tree of Contemplative Practices.

  6. Applying Web-Based Tools for Research, Engineering, and Operations

    Science.gov (United States)

    Ivancic, William D.

    2011-01-01

    Personnel in the NASA Glenn Research Center Network and Architectures branch have performed a variety of research related to space-based sensor webs, network centric operations, security and delay tolerant networking (DTN). Quality documentation and communications, real-time monitoring and information dissemination are critical in order to perform quality research while maintaining low cost and utilizing multiple remote systems. This has been accomplished using a variety of Internet technologies often operating simultaneously. This paper describes important features of various technologies and provides a number of real-world examples of how combining Internet technologies can enable a virtual team to act efficiently as one unit to perform advanced research in operational systems. Finally, real and potential abuses of power and manipulation of information and information access is addressed.

  7. A Primer On Consumer Marketing Research, Procedures, Methods, And Tools

    Science.gov (United States)

    1994-03-01

    THE FOLLOWING IS ONE OF A SERIES OF PAPERS DEVELOPED OR PRODUCED BY THE ECONOMIC ANALYSIS DIVISION OF THE JOHN A. VOLPE NATIONAL TRANSPORTATION SYSTEMS CENTER AS PART OF ITS RESEARCH PROJECT LOOKING INTO ISSUES SURROUNDING : USER RESPONSE AND MARKET ...

  8. Stable isotopes: essential tools in biological and medical research

    Energy Technology Data Exchange (ETDEWEB)

    Klein, P. D.; Hachey, D. L.; Kreek, M. J.; Schoeller, D. A.

    1977-01-01

    Recent developments in the use of the stable isotopes, /sup 13/C, /sup 15/N, /sup 17/O, and /sup 18/O, as tracers in research studies in the fields of biology, medicine, pharmacology, and agriculture are briefly reviewed. (CH)

  9. Including Media in Field Research and Becoming Part of the Science Media

    Science.gov (United States)

    Pelto, M. S.

    2015-12-01

    There are two primary strategies that I have pursued over the last decade to engage the media, policy makers, and public; after two decades of typical scientific publication methods. An effective method to engage the media with our ongoing 32 year glacier field research program has been to invite media members to join us in the field. From climate videographers to traditional reporters we have had a member of the media with us in nine of the last ten field seasons; two in 2015. The resulting stories have led to several awards for the journalists and an ongoing relationship with our research program. The second part of this science research communication strategy is to have readily available material on specific topics for the media to utilize; this requires social media outreach. The primary outlet media find is the AGU Blog: From a Glacier's Perspective. This blog pubishes two articles a week on a specific glacier's response to climate change. The blog yields on average a media contact on every fourth blog post in 2015. The contacts revolve around specific local glacier information published on the blog. The goal of each blog post is to tell a story about how each glacier is impacted by climate change.

  10. Understanding Research Impact: A Review of Existing and Emerging Tools for Nursing.

    Science.gov (United States)

    Wimmer, Erin N; Rethlefsen, Melissa L; Jarvis, Christy; Shipman, Jean P

    Researchers and educators are required to show the impact they have in their field when they apply for promotion or extramural funding. There are several tools available for nursing faculty to consult as they build a research impact profile. This article highlights both traditional and more novel tools, the impact metrics they calculate, and why the tools are particularly relevant to the field of nursing. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. "Mind Blown"--Including Exercise Science Students as Research Assistants to Reduce Ageist Perceptions

    Science.gov (United States)

    Forlenza, Samuel T.; Bourassa, Dara

    2017-01-01

    The amount of older adults is increasing rapidly and the demands of an aging population will need to be met by professionals in many fields, including exercise science. However, many undergraduate students do not want to work with older adults. Therefore, this qualitative study sought to examine the experiences and perceptions of exercise science…

  12. Australian Disaster Research Directory (Including Some Contributions from New Zealand). Provisional--1983.

    Science.gov (United States)

    1983-06-01

    Adelaide, GPO Box 438, Adelaide, S,:uth Australia 5001 (08) 2285333 Kenneth A Brown BDS, FICD, Senior Lecturer in Forensic Odontology , Department of...which included projects relevant to disaster victim identification, as follows: To develop for Australia internationally compatible odontological methods

  13. Rating of Included Trials on the Efficacy–Effectiveness Spectrum : development of a new tool for systematic reviews

    NARCIS (Netherlands)

    Wieland, L. Susan; Berman, Brian M.; Altman, Douglas G.; Barth, Jürgen; Bouter, Lex M.; D'Adamo, Christopher R.; Linde, Klaus; Moher, David; Mullins, C. Daniel; Treweek, Shaun; Tunis, Sean; van der Windt, Danielle A.; Zwarenstein, Merrick; Witt, Claudia

    2017-01-01

    Background and Objective Randomized trials may be designed to provide evidence more strongly related to efficacy or effectiveness of an intervention. When systematic reviews are used to inform clinical or policy decisions, it is important to know the efficacy–effectiveness nature of the included

  14. The airborne infrared scanner as a geophysical research tool

    Science.gov (United States)

    Friedman, Jules D.

    1970-01-01

    The infrared scanner is proving to be an effective anomaly-mapping tool, albeit one which depicts surface emission directly and heat mass transfer from depths only indirectly and at a threshold level 50 to 100 times the normal conductive heat flow of the earth. Moreover, successive terrain observations are affected by time-dependent variables such as the diurnal and seasonal warming and cooling cycle of a point on the earth's surface. In planning precise air borne surveys of radiant flux from the earth's surface, account must be taken of background noise created by variations in micrometeorological factors and emissivity of surface materials, as well as the diurnal temperature cycle. The effect of the diurnal cycle may be minimized by planning predawn aerial surveys. In fact, the diurnal change is very small for most water bodies and the emissivity factor for water (e) =~ 1 so a minimum background noise is characteristic of scanner records of calm water surfaces.

  15. Limits of Generalizing in Education Research: Why Criteria for Research Generalization Should Include Population Heterogeneity and Uses of Knowledge Claims

    Science.gov (United States)

    Ercikan, Kadriye; Roth, Wolff-Michael

    2014-01-01

    Context: Generalization is a critical concept in all research designed to generate knowledge that applies to all elements of a unit (population) while studying only a subset of these elements (sample). Commonly applied criteria for generalizing focus on experimental design or representativeness of samples of the population of units. The criteria…

  16. Drawing and acting as user experience research tools

    DEFF Research Database (Denmark)

    Fleury, Alexandre

    2012-01-01

    This paper discusses the use of participant-generated drawings and drama workshops as user experience research methods. In spite of the lack of background literature on how drawings can generate useful insights on HCI issues, drawings have been successfully used in other research fields....... On the contrary, drama workshops seem to be increasingly popular in recent participatory design research. After briefly introducing such previous work, three case studies are presented, illustrating the use of drawing and drama workshops when investigating the relationship between media technology users and two...... specific devices, namely televisions and mobile phones. The paper focuses on the methods and discusses their benefits and the challenges associated with their application. In particular, the findings are compared to those collected through a quantitative cross-cultural survey. The experience gathered...

  17. The credibility crisis in research: Can economics tools help?

    Science.gov (United States)

    Gall, Thomas; Ioannidis, John P A; Maniadis, Zacharias

    2017-04-01

    The issue of nonreplicable evidence has attracted considerable attention across biomedical and other sciences. This concern is accompanied by an increasing interest in reforming research incentives and practices. How to optimally perform these reforms is a scientific problem in itself, and economics has several scientific methods that can help evaluate research reforms. Here, we review these methods and show their potential. Prominent among them are mathematical modeling and laboratory experiments that constitute affordable ways to approximate the effects of policies with wide-ranging implications.

  18. South Baltic representative coastal field surveys, including monitoring at the Coastal Research Station in Lubiatowo, Poland

    Science.gov (United States)

    Ostrowski, Rafał; Schönhofer, Jan; Szmytkiewicz, Piotr

    2016-10-01

    The paper contains a brief description of selected investigations carried out in the south Baltic coastal zone, with the particular focus on the history and recent activities conducted at the Coastal Research Station in Lubiatowo (CRS Lubiatowo), Poland. These activities comprise field investigations of nearshore hydrodynamic, lithodynamic, and morphodynamic processes. The study area is a sandy multi-bar shore with a mild slope, much exposed to the impact of waves approaching from NW-NE sector. The shore has a dissipative character which means that the wave energy is subject to gradual dissipation in the nearshore zone and only a small part of this energy is reflected by the shore. Due to the big wind fetch in N-NNE direction, the location of CRS Lubiatowo is favourable to registration of the maximum values of parameters of hydrodynamic and morphodynamic processes which occur in the Baltic during extreme storms.

  19. Recorded peer video chat as a research and development tool

    DEFF Research Database (Denmark)

    Otrel-Cass, Kathrin; Cowie, Bronwen

    2016-01-01

    When practising teachers take time to exchange their experiences and reflect on their teaching realities as critical friends, they add meaning and depth to educational research. When peer talk is facilitated through video chat platforms, teachers can meet (virtually) face to face even when...

  20. Ready Reference Tools: EBSCO Topic Search and SIRS Researcher.

    Science.gov (United States)

    Goins, Sharon; Dayment, Lu

    1998-01-01

    Discussion of ready reference and current events collections in high school libraries focuses on a comparison of two CD-ROM services, EBSCO Topic Search and the SIRS Researcher. Considers licensing; access; search strategies; viewing articles; currency; printing; added value features; and advantages of CD-ROMs. (LRW)

  1. Using smartphones in survey research: a multifunctional tool

    NARCIS (Netherlands)

    Nathalie Sonck; Henk Fernee

    2013-01-01

    Smartphones and apps offer an innovative means of collecting data from the public. The Netherlands Institute for Social Research | SCP has been engaged in one of the first experiments involving the use of a smartphone app to collect time use data recorded by means of an electronic diary. Is it

  2. New evaluation tool now available to assess research quality | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-04-25

    Apr 25, 2016 ... Report: The value-for-money discourse: risks and opportunities for research for development. The value-for-money discourse is gaining prominence in all areas of society. It also increasingly affects what matters to donors. View moreReport: The value-for-money discourse: risks and opportunities for ...

  3. New research and tools lead to improved earthquake alerting protocols

    Science.gov (United States)

    Wald, David J.

    2009-01-01

    What’s the best way to get alerted about the occurrence and potential impact of an earthquake? The answer to that question has changed dramatically of late, in part due to improvements in earthquake science, and in part by the implementation of new research in the delivery of earthquake information

  4. Microelectrodes as novel research tools for environmental biofilm studies

    International Nuclear Information System (INIS)

    Yu, T.; Lu, R.; Bishop, L.

    2002-01-01

    Biofilm processes are widely utilized in environmental engineering for biodegradation of contaminated waters, gases and soils. It is important to understand the structure and functions of biofilms. Microelectrodes are novel experimental tools for environmental biofilm studies. The authors reviewed the techniques of oxygen, sulfide, redox potential and pH microelectrode. These microelectrodes have tip diameters of 3 to 20 μm, resulting a high spatial resolution. They enable us directly measure the chemical conditions as results of microbial activities in biofilms. The authors also reported the laboratory and field studies of wastewater biofilms using microelectrode techniques. The results of these studies provided experimental evidence on the stratification of microbial processes and the associated redox potential change in wastewater biofilms: (1) The oxygen penetration depth was only a fraction of the biofilm thickness. This observation, first made under laboratory conditions, has been confirmed under field conditions. (2) The biofilms with both aerobic oxidation and sulfate reduction had a clearly stratified structure. This was evidenced by a sharp decrease of redox potential near the interface between the aerobic zone and the sulfate reduction zone within the biofilm. In this type of biofilms, aerobic oxidation took place only in a shallow layer near the biofilm surface and sulfate reduction occurred in the deeper anoxic zone. (3) The redox potential changed with the shift of primary microbial process in biofilms, indicating that it is possible to use redox potential to help illustrate the structure and functions of biofilms. (author)

  5. Developing a Research Tool to Gauge Student Metacognition

    Science.gov (United States)

    McInerny, Alistair; Boudreaux, Andrew; Rishal, Sepideh; Clare, Kelci

    2012-10-01

    Metacognition refers to the family of thought processes and skills used to evaluate and manage learning. A research and curriculum development project underway at Western Washington University uses introductory physics labs as a context to promote students' abilities to learn and apply metacognitive skills. A required ``narrative reflection'' has been incorporated as a weekly end-of-lab assignment. The goal of the narrative reflection is to encourage and support student metacognition while generating written artifacts that can be used by researchers to study metacognition in action. We have developed a Reflective Thinking Rubric (RTR) to analyze scanned narrative reflections. The RTR codes student writing for Metacognitive Elements, identifiable steps or aspects of metacognitive thinking at a variety of levels of sophistication. We hope to use the RTR to monitor the effect of weekly reflection on metacognitive ability and to search for correlations between metacognitive ability and conceptual understanding.

  6. Tools for Reproducibility and Extensibility in Scientific Research

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    Open inquiry through reproducing results is fundamental to the scientific process. Contemporary research relies on software engineering pipelines to collect, process, and analyze data. The open source projects within Project Jupyter facilitate these objectives by bringing software engineering within the context of scientific communication. We will highlight specific projects that are computational building blocks for scientific communication, starting with the Jupyter Notebook. We will also explore applications of projects that build off of the Notebook such as Binder, JupyterHub, and repo2docker. We will discuss how these projects can individually and jointly improve reproducibility in scientific communication. Finally, we will demonstrate applications of Jupyter software that allow researchers to build upon the code of other scientists, both to extend their work and the work of others.    There will be a follow-up demo session in the afternoon, hosted by iML. Details can be foun...

  7. A vibrating quartz fork - a tool for cryogenic helium research

    Czech Academy of Sciences Publication Activity Database

    Blažková, Michaela; Člověčko, M.; Eltsov, V. B.; Gažo, E.; de Graaf, R.; Hosio, J.J.; Krusius, M.; Schmoranzer, D.; Schoepe, W.; Skrbek, Ladislav; Skyba, P.; Solntsev, R.E.; Vinen, W. F.

    2008-01-01

    Roč. 150, - (2008), s. 525-535 ISSN 0022-2291 R&D Projects: GA ČR GA202/05/0218 Grant - others:GAUK(CZ) 7953/2007; Transnational Access Programme(XE) RITA-CT-2003-505313 Institutional research plan: CEZ:AV0Z10100520 Keywords : normal 3He * superfluid 3He * superfluid 4He * turbulence, * cavitation * quartz tuning fork Subject RIV: BK - Fluid Dynamics Impact factor: 1.034, year: 2008

  8. Selected Research Tools in Economics, Labor and Industrial Relations.

    Science.gov (United States)

    Kaye, Ronald J.

    Twenty-two indexing and abstracting services and general reference sources in the areas of labor and industrial relations are listed in this selective bibliography for users of State University of New York at Albany Libraries. Classification numbers are included for each source and most have annotations. Materials are listed under four…

  9. A tool to assess sex-gender when selecting health research projects.

    Science.gov (United States)

    Tomás, Concepción; Yago, Teresa; Eguiluz, Mercedes; Samitier, M A Luisa; Oliveros, Teresa; Palacios, Gemma

    2015-04-01

    To validate the questionnaire "Gender Perspective in Health Research" (GPIHR) to assess the inclusion of gender perspective in research projects. Validation study in two stages. Feasibility was analysed in the first, and reliability, internal consistence and validity in the second. Aragón Institute of Health Science, Aragón, Spain. GPIHR was applied to 118 research projects funded in national and international competitive tenders from 2003 to 2012. Analysis of inter- and intra-observer reliability with Kappa index and internal consistency with Cronbach's alpha. Content validity analysed through literature review and construct validity with an exploratory factor analysis. Validated GPIHR has 10 questions: 3 in the introduction, 1 for objectives, 3 for methodology and 3 for research purpose. Average time of application was 13min Inter-observer reliability (Kappa) varied between 0.35 and 0.94 and intra-observer between 0.40 and 0.94. Theoretical construct is supported in the literature. Factor analysis identifies three levels of GP inclusion: "difference by sex", "gender sensitive" and "feminist research" with an internal consistency of 0.64, 0.87 and 0.81, respectively, which explain 74.78% of variance. GPIHR questionnaire is a valid tool to assess GP and useful for those researchers who would like to include GP in their projects. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

  10. Regional models - Emerging research tools for synoptic meteorologists

    Science.gov (United States)

    Keyser, Daniel; Uccellini, Louis W.

    1987-01-01

    A number of regional-scale numerical weather prediction models are discussed together with their application to the study of the structure and the dynamics of mesoscale phenomena. Consideration is given to investigations of natural phenomena (such as midlatitude cyclones and related baroclinic disturbances; upper-level jet-front systems; surface frontal zones, squall lines, and rain bands; mesoscale convective systems; and severe-storm environments) in which two operational models and four research models are used for regional-model studies. It is shown that these models provide investigators with four-dimensional dynamically consistent data sets to supplement and extend those available from observations.

  11. [Scientific information systems: tools for measures of biomedical research impact].

    Science.gov (United States)

    Navarrete Cortés, José; Banqueri Ozáez, Jesús

    2008-12-01

    The present article provides an analysis and description of the use of scientific information systems as instruments to measure and monitor results and investigative activity in biomedicine. Based on the current situation concerning the use and implementation of these systems, we offer a detailed description of the actors of these systems and propose a functional architecture for this class of software. In addition, the instruments that these types of systems offer for the measurement of the impact of the results of research are described in depth, as these instruments can help in decision making. Finally, a selection of national and international scientific information systems are listed and reviewed.

  12. NASA Global Hawk: A New Tool for Earth Science Research

    Science.gov (United States)

    Hall, Phill

    2009-01-01

    This slide presentation reviews the Global Hawk, a unmanned aerial vehicle (UAV) that NASA plans to use for Earth Sciences research. The Global Hawk is the world's first fully autonomous high-altitude, long-endurance aircraft, and is capable of conducting long duration missions. Plans are being made for the use of the aircraft on missions in the Arctic, Pacific and Western Atlantic Oceans. There are slides showing the Global Hawk Operations Center (GHOC), Flight Control and Air Traffic Control Communications Architecture, and Payload Integration and Accommodations on the Global Hawk. The first science campaign, planned for a study of the Pacific Ocean, is reviewed.

  13. Digital storytelling: an innovative tool for practice, education, and research.

    Science.gov (United States)

    Lal, Shalini; Donnelly, Catherine; Shin, Jennifer

    2015-01-01

    Digital storytelling is a method of using storytelling, group work, and modern technology to facilitate the creation of 2-3 minute multi-media video clips to convey personal or community stories. Digital storytelling is being used within the health care field; however, there has been limited documentation of its application within occupational therapy. This paper introduces digital storytelling and proposes how it can be applied in occupational therapy clinical practice, education, and research. The ethical and methodological challenges in relation to using the method are also discussed.

  14. An Application Tool for Visualizing Research Work on Landslides

    OpenAIRE

    Lepp, Katarina

    2014-01-01

    This report describes the process of organizing the research material of a PhD thesis into a database, and the development of an application in order to access the information. The thesis relates to rainfall-induced landslides in the capital of Honduras: The data are a collection of press-based information related to these landslides over a period of 26 years and stored in several Excel files. The task has been to analyze the data and organize them into a conceptual database model. After proc...

  15. [Introduction to Research Electronic Data Capture (REDCap) and REDCap2SDTM, a Conversion Tool to Facilitate Clinical Research Data Sharing].

    Science.gov (United States)

    Yamamoto, Keiichi

    2017-07-01

    Clinical Data Interchange Standards Consortium (CDISC), Study Data Tabulation Model (SDTM) is used in new drug application studies and for sharing and reuse of accumulated clinical research data. Clinical trial manuscripts submitted to International Committee of Medical Journal Editors member journals are required to contain a statement on data sharing. We introduce here Research Electronic Data Capture (REDCap) and REDCap2SDTM, a tool for converting research data to CDISC SDTM for facilitating data sharing. This tool will help reduce the workload in new drug application studies and allow the effective reuse of clinical research data.

  16. Electrostatic Levitation: A Tool to Support Materials Research in Microgravity

    Science.gov (United States)

    Rogers, Jan; SanSoucie, Mike

    2012-01-01

    Containerless processing represents an important topic for materials research in microgravity. Levitated specimens are free from contact with a container, which permits studies of deeply undercooled melts, and high-temperature, highly reactive materials. Containerless processing provides data for studies of thermophysical properties, phase equilibria, metastable state formation, microstructure formation, undercooling, and nucleation. The European Space Agency (ESA) and the German Aerospace Center (DLR) jointly developed an electromagnetic levitator facility (MSL-EML) for containerless materials processing in space. The electrostatic levitator (ESL) facility at the Marshall Space Flight Center provides support for the development of containerless processing studies for the ISS. Apparatus and techniques have been developed to use the ESL to provide data for phase diagram determination, creep resistance, emissivity, specific heat, density/thermal expansion, viscosity, surface tension and triggered nucleation of melts. The capabilities and results from selected ESL-based characterization studies performed at NASA's Marshall Space Flight Center will be presented.

  17. FACTORIAL CORRESPONDENCES ANALYSIS – A TOOL IN TOURISM MOTIVATION RESEARCH

    Directory of Open Access Journals (Sweden)

    Ion Danut I. JUGANARU

    2016-05-01

    Full Text Available This study aims at analyzing the distribution of tourist flows in 2014, from 25 European countries, on three main categories of trip purposes, and assumes that there are differences or similarities between the tourists’ countries of residence and their trip purposes. "Purpose'' is a multidimensional concept used in marketing research, most often for understanding consumer behavior, and for identifying market segments or customer target groups, reunited in terms of similar characteristics. Being aware that the decision of choice/ purchase is based on purposes, their knowledge proves useful in designing strategies to increase the satisfaction level provided to the customer. The statistical method used in this paper is the factorial correspondences analysis. In our opinion, the identification, by this method, of the existence of differences or similarities between the tourists’ countries of residence and their trip purposes can represent a useful step in studying the tourism market and the choice/ reformulation of strategies.

  18. Composite poplars: a novel tool for ectomycorrhizal research.

    Science.gov (United States)

    Neb, Dimitri; Das, Arpita; Hintelmann, Annette; Nehls, Uwe

    2017-12-01

    Composite poplars were used for ectomycorrhiza formation. Structurally normal mycorrhizas of transgenic roots revealed better fungal sugar support. Targeting fluorescent proteins to peroxisomes allowed easy in planta visualization of successful transformation. A bottle neck in ectomycorrhizal research is the time demand for generation of transgenic plants. An alternative strategy for such root-centered research might be the formation of the so-called composite plants, where transgenic roots are formed by non-transgenic shoots. We have developed an Agrobacterium rhizogenes-mediated root transformation protocol using axenic Populus tremula × tremuloides and P. tremula × alba cuttings. When comparing four different bacterial strains, A. rhizogenes K599 turned out to be the most suitable for poplar transformation. Transgenic roots revealed only minor hairy root phenotype when plants were grown on agar plates with synthetic growth medium in the absence of a sugar source. When using different ectomycorrhizal fungi, formation of ectomycorrhizas by transgenic roots of composite poplars was not affected and mycorrhizas were anatomically indistinguishable from mycorrhizas of non-transgenic roots. Elevated trehalose content and marker gene expression, however, pointed towards somewhat better fungal carbon nutrition in ectomycorrhizas of transgenic compared to non-transgenic roots. Cell wall autofluorescence of poplar fine roots is an issue that can limit the use of fluorescent proteins as visual markers for in planta analysis, especially after ectomycorrhiza formation. By targeting marker proteins to peroxisomes, sensitive fluorescence detection, easily distinguishable from cell wall autofluorescence, was obtained for both poplar fine roots and ectomycorrhizas.

  19. Consensus Coding as a Tool in Visual Appearance Research

    Directory of Open Access Journals (Sweden)

    D R Simmons

    2011-04-01

    Full Text Available A common problem in visual appearance research is how to quantitatively characterise the visual appearance of a region of an image which is categorised by human observers in the same way. An example of this is scarring in medical images (Ayoub et al, 2010, The Cleft-Palate Craniofacial Journal, in press. We have argued that “scarriness” is itself a visual appearance descriptor which summarises the distinctive combination of colour, texture and shape information which allows us to distinguish scarred from non-scarred tissue (Simmons et al, ECVP 2009. Other potential descriptors for other image classes would be “metallic”, “natural”, or “liquid”. Having developed an automatic algorithm to locate scars in medical images, we then tested “ground truth” by asking untrained observers to draw around the region of scarring. The shape and size of the scar on the image was defined by building a contour plot of the agreement between observers' outlines and thresholding at the point above which 50% of the observers agreed: a consensus coding scheme. Based on the variability in the amount of overlap between the scar as defined by the algorithm, and the consensus scar of the observers, we have concluded that the algorithm does not completely capture the putative appearance descriptor “scarriness”. A simultaneous analysis of qualitative descriptions of the scarring by the observers revealed that other image features than those encoded by the algorithm (colour and texture might be important, such as scar boundary shape. This approach to visual appearance research in medical imaging has potential applications in other application areas, such as botany, geology and archaeology.

  20. A validated set of tool pictures with matched objects and non-objects for laterality research.

    Science.gov (United States)

    Verma, Ark; Brysbaert, Marc

    2015-01-01

    Neuropsychological and neuroimaging research has established that knowledge related to tool use and tool recognition is lateralized to the left cerebral hemisphere. Recently, behavioural studies with the visual half-field technique have confirmed the lateralization. A limitation of this research was that different sets of stimuli had to be used for the comparison of tools to other objects and objects to non-objects. Therefore, we developed a new set of stimuli containing matched triplets of tools, other objects and non-objects. With the new stimulus set, we successfully replicated the findings of no visual field advantage for objects in an object recognition task combined with a significant right visual field advantage for tools in a tool recognition task. The set of stimuli is available as supplemental data to this article.

  1. An informatics supported web-based data annotation and query tool to expedite translational research for head and neck malignancies

    International Nuclear Information System (INIS)

    Amin, Waqas; Kang, Hyunseok P; Egloff, Ann Marie; Singh, Harpreet; Trent, Kerry; Ridge-Hetrick, Jennifer; Seethala, Raja R; Grandis, Jennifer; Parwani, Anil V

    2009-01-01

    The Specialized Program of Research Excellence (SPORE) in Head and Neck Cancer neoplasm virtual biorepository is a bioinformatics-supported system to incorporate data from various clinical, pathological, and molecular systems into a single architecture based on a set of common data elements (CDEs) that provides semantic and syntactic interoperability of data sets. The various components of this annotation tool include the Development of Common Data Elements (CDEs) that are derived from College of American Pathologists (CAP) Checklist and North American Association of Central Cancer Registries (NAACR) standards. The Data Entry Tool is a portable and flexible Oracle-based data entry device, which is an easily mastered web-based tool. The Data Query Tool helps investigators and researchers to search de-identified information within the warehouse/resource through a 'point and click' interface, thus enabling only the selected data elements to be essentially copied into a data mart using a multi dimensional model from the warehouse's relational structure. The SPORE Head and Neck Neoplasm Database contains multimodal datasets that are accessible to investigators via an easy to use query tool. The database currently holds 6553 cases and 10607 tumor accessions. Among these, there are 965 metastatic, 4227 primary, 1369 recurrent, and 483 new primary cases. The data disclosure is strictly regulated by user's authorization. The SPORE Head and Neck Neoplasm Virtual Biorepository is a robust translational biomedical informatics tool that can facilitate basic science, clinical, and translational research. The Data Query Tool acts as a central source providing a mechanism for researchers to efficiently find clinically annotated datasets and biospecimens that are relevant to their research areas. The tool protects patient privacy by revealing only de-identified data in accordance with regulations and approvals of the IRB and scientific review committee

  2. Research on Key Technologies of Unit-Based CNC Machine Tool Assembly Design

    OpenAIRE

    Zhongqi Sheng; Lei Zhang; Hualong Xie; Changchun Liu

    2014-01-01

    Assembly is the part that produces the maximum workload and consumed time during product design and manufacturing process. CNC machine tool is the key basic equipment in manufacturing industry and research on assembly design technologies of CNC machine tool has theoretical significance and practical value. This study established a simplified ASRG for CNC machine tool. The connection between parts, semantic information of transmission, and geometric constraint information were quantified to as...

  3. Low-rank coal research annual report, July 1, 1989--June 30, 1990 including quarterly report, April--June 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-11-01

    Research programs in the following areas are presented: control technology and coal preparation; advance research and technology development; combustion; liquefaction; and gasification. Sixteen projects are included. Selected items have been processed separately for inclusion in the Energy Science and Technology Database.

  4. DEVELOPMENT OF AN ENVIRONMENTAL RATING TOOL FOR BUILDINGS THROUGH A NEW KIND OF DIALOGUE BETWEEN STAKEHOLDERS AND RESEARCHERS

    Directory of Open Access Journals (Sweden)

    Mauritz Glaumann

    2009-03-01

    Full Text Available Buildings need to be more environmentally benign since the building sector is responsible for about 40% of all of energy and material use in Sweden. For this reason a unique cooperation between companies, municipalities and the Government called “Building- Living and Property Management for the future”, in short “The Building Living Dialogue” has going on since 2003. The project focuses on: a healthy indoor environment, b efficient use of energy, and c efficient resource management. In accordance with the dialogue targets, two research projects were initiated aiming at developing an Environmental rating tool taking into accounts both building sector requirements and expectations and national and international research findings. This paper describes the first phase in the development work where stakeholders and researchers cooperate. It includes results from inventories and based on this experience discusses procedures for developing assessment tools and what the desirable features of a broadly accepted building rating tool could be.

  5. Advancing Research in Second Language Writing through Computational Tools and Machine Learning Techniques: A Research Agenda

    Science.gov (United States)

    Crossley, Scott A.

    2013-01-01

    This paper provides an agenda for replication studies focusing on second language (L2) writing and the use of natural language processing (NLP) tools and machine learning algorithms. Specifically, it introduces a range of the available NLP tools and machine learning algorithms and demonstrates how these could be used to replicate seminal studies…

  6. Positioning Mentoring as a Coach Development Tool: Recommendations for Future Practice and Research

    Science.gov (United States)

    McQuade, Sarah; Davis, Louise; Nash, Christine

    2015-01-01

    Current thinking in coach education advocates mentoring as a development tool to connect theory and practice. However, little empirical evidence exists to evaluate the effectiveness of mentoring as a coach development tool. Business, education, and nursing precede the coaching industry in their mentoring practice, and research findings offered in…

  7. 'Screening audit' as a quality assurance tool in good clinical practice compliant research environments.

    Science.gov (United States)

    Park, Sinyoung; Nam, Chung Mo; Park, Sejung; Noh, Yang Hee; Ahn, Cho Rong; Yu, Wan Sun; Kim, Bo Kyung; Kim, Seung Min; Kim, Jin Seok; Rha, Sun Young

    2018-04-25

    With the growing amount of clinical research, regulations and research ethics are becoming more stringent. This trend introduces a need for quality assurance measures for ensuring adherence to research ethics and human research protection beyond Institutional Review Board approval. Audits, one of the most effective tools for assessing quality assurance, are measures used to evaluate Good Clinical Practice (GCP) and protocol compliance in clinical research. However, they are laborious, time consuming, and require expertise. Therefore, we developed a simple auditing process (a screening audit) and evaluated its feasibility and effectiveness. The screening audit was developed using a routine audit checklist based on the Severance Hospital's Human Research Protection Program policies and procedures. The measure includes 20 questions, and results are summarized in five categories of audit findings. We analyzed 462 studies that were reviewed by the Severance Hospital Human Research Protection Center between 2013 and 2017. We retrospectively analyzed research characteristics, reply rate, audit findings, associated factors and post-screening audit compliance, etc. RESULTS: Investigator reply rates gradually increased, except for the first year (73% → 26% → 53% → 49% → 55%). The studies were graded as "critical," "major," "minor," and "not a finding" (11.9, 39.0, 42.9, and 6.3%, respectively), based on findings and number of deficiencies. The auditors' decisions showed fair agreement with weighted kappa values of 0.316, 0.339, and 0.373. Low-risk level studies, single center studies, and non-phase clinical research showed more prevalent frequencies of being "major" or "critical" (p = 0.002, < 0.0001, < 0.0001, respectively). Inappropriateness of documents, failure to obtain informed consent, inappropriateness of informed consent process, and failure to protect participants' personal information were associated with higher audit grade (p

  8. Conceptualising the Use of Facebook in Ethnographic Research: As Tool, as Data and as Context

    Science.gov (United States)

    Baker, Sally

    2013-01-01

    This article proposes a three-part conceptualisation of the use of Facebook in ethnographic research: as a tool, as data and as context. Longitudinal research with young adults at a time of significant change provides many challenges for the ethnographic researcher, such as maintaining channels of communication and high rates of participant…

  9. Searching for New Directions: Developing MA Action Research Project as a Tool for Teaching

    Science.gov (United States)

    Lee, Young Ah; Wang, Ye

    2012-01-01

    Action research has been recognized as a useful professional development tool for teaching, but for inservice teachers, conducting action research can be challenging. Their learning about action research can be influenced by social situations--whether in an MA (Master of Arts) program or other professional development. The purpose of this…

  10. An Evaluation of the Middle East Research Training Initiative Tool in Assessing Effective Functioning of Research Ethics Committees.

    Science.gov (United States)

    Jaoko, Walter; Bukusi, Elizabeth; Davis, Arlene M

    2016-10-01

    The effective functioning of a research ethics committee (REC) can be evaluated using self-assessment tools. The Middle East Research Ethics Training Initiative (MERETI) tool can be used by one member, typically the Chair, to score an REC. The consistency of these scores across several members of an REC has never been evaluated. This study examined whether results would be consistent irrespective of who conducts the assessment. One REC's effective functioning was assessed by several members ( n = 13). The Chair's scores were compared with scores of other members in relation to their duration of REC membership, research ethics training, gender, and employer's institutional affiliation to the REC. The Chair's overall score was higher than the other members' scores by 11%. No significant differences in scores were obtained in relation to duration of REC membership ( p = .72), interval since last research ethics training ( p = .94), and gender ( p = .27). The MERETI tool is thus consistent irrespective of who performs the assessment.

  11. MoDOT pavement preservation research program volume IV, pavement evaluation tools-data collection methods.

    Science.gov (United States)

    2015-10-01

    The overarching goal of the MoDOT Pavement Preservation Research Program, Task 3: Pavement Evaluation Tools Data : Collection Methods was to identify and evaluate methods to rapidly obtain network-level and project-level information relevant to :...

  12. Facebook as a recruitment tool for adolescent health research: a systematic review.

    Science.gov (United States)

    Amon, Krestina L; Campbell, Andrew J; Hawke, Catherine; Steinbeck, Katharine

    2014-01-01

    Researchers are increasingly using social media to recruit participants to surveys and clinical studies. However, the evidence of the efficacy and validity of adolescent recruitment through Facebook is yet to be established. To conduct a systematic review of the literature on the use of Facebook to recruit adolescents for health research. Nine electronic databases and reference lists were searched for articles published between 2004 and 2013. Studies were included in the review if: 1) participants were aged ≥ 10 to ≤ 18 years, 2) studies addressed a physical or mental health issue, 3) Facebook was identified as a recruitment tool, 4) recruitment details using Facebook were outlined in the methods section and considered in the discussion, or information was obtained by contacting the authors, 5) results revealed how many participants were recruited using Facebook, and 6) studies addressed how adolescent consent and/or parental consent was obtained. Titles, abstracts, and keywords were scanned and duplicates removed by 2 reviewers. Full text was evaluated for inclusion criteria, and 2 reviewers independently extracted data. The search resulted in 587 publications, of which 25 full-text papers were analyzed. Six studies met all the criteria for inclusion in the review. Three recruitment methods using Facebook was identified: 1) paid Facebook advertising, 2) use of the Facebook search tool, and 3) creation and use of a Facebook Page. Eligible studies described the use of paid Facebook advertising and Facebook as a search tool as methods to successfully recruit adolescent participants. Online and verbal consent was obtained from participants recruited from Facebook. Copyright © 2014 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

  13. Integrating research tools to support the management of social-ecological systems under climate change

    Directory of Open Access Journals (Sweden)

    Brian W. Miller

    2014-09-01

    Full Text Available Developing resource management strategies in the face of climate change is complicated by the considerable uncertainty associated with projections of climate and its impacts and by the complex interactions between social and ecological variables. The broad, interconnected nature of this challenge has resulted in calls for analytical frameworks that integrate research tools and can support natural resource management decision making in the face of uncertainty and complex interactions. We respond to this call by first reviewing three methods that have proven useful for climate change research, but whose application and development have been largely isolated: species distribution modeling, scenario planning, and simulation modeling. Species distribution models provide data-driven estimates of the future distributions of species of interest, but they face several limitations and their output alone is not sufficient to guide complex decisions for how best to manage resources given social and economic considerations along with dynamic and uncertain future conditions. Researchers and managers are increasingly exploring potential futures of social-ecological systems through scenario planning, but this process often lacks quantitative response modeling and validation procedures. Simulation models are well placed to provide added rigor to scenario planning because of their ability to reproduce complex system dynamics, but the scenarios and management options explored in simulations are often not developed by stakeholders, and there is not a clear consensus on how to include climate model outputs. We see these strengths and weaknesses as complementarities and offer an analytical framework for integrating these three tools. We then describe the ways in which this framework can help shift climate change research from useful to usable.

  14. Visualising the past: potential applications of Geospatial tools to paleoclimate research

    Science.gov (United States)

    Cook, A.; Turney, C. S.

    2012-12-01

    Recent advances in geospatial data acquisition, analysis and web-based data sharing offer new possibilities for understanding and visualising past modes of change. The availability, accessibility and cost-effectiveness of data is better than ever. Researchers can access remotely sensed data including terrain models; use secondary data from large consolidated repositories; make more accurate field measurements and combine data from disparate sources to form a single asset. An increase in the quantity and consistency of data is coupled with subtle yet significant improvements to the way in which geospatial systems manage data interoperability, topological and textual integrity, resulting in more stable analytical and modelling environments. Essentially, researchers now have greater control and more confidence in analytical tools and outputs. Web-based data sharing is growing rapidly, enabling researchers to publish and consume data directly into their spatial systems through OGC-compliant Web Map Services (WMS), Web Feature Services (WFS) and Web Coverage Services (WCS). This has been implemented at institutional, organisational and project scale around the globe. Some institutions have gone one step further and established Spatial Data Infrastructures (SDI) based on Federated Data Structures where the participating data owners retain control over who has access to what. It is important that advances in knowledge are transferred to audiences outside the scientific community in a way that is interesting and meaningful. The visualisation of paleodata through multi-media offers significant opportunities to highlight the parallels and distinctions between past climate dynamics and the challenges of today and tomorrow. Here we present an assessment of key innovations that demonstrate how Geospatial tools can be applied to palaeo-research and used to communicate the results to a diverse array of audiences in the digital age.

  15. Integrating research tools to support the management of social-ecological systems under climate change

    Science.gov (United States)

    Miller, Brian W.; Morisette, Jeffrey T.

    2014-01-01

    Developing resource management strategies in the face of climate change is complicated by the considerable uncertainty associated with projections of climate and its impacts and by the complex interactions between social and ecological variables. The broad, interconnected nature of this challenge has resulted in calls for analytical frameworks that integrate research tools and can support natural resource management decision making in the face of uncertainty and complex interactions. We respond to this call by first reviewing three methods that have proven useful for climate change research, but whose application and development have been largely isolated: species distribution modeling, scenario planning, and simulation modeling. Species distribution models provide data-driven estimates of the future distributions of species of interest, but they face several limitations and their output alone is not sufficient to guide complex decisions for how best to manage resources given social and economic considerations along with dynamic and uncertain future conditions. Researchers and managers are increasingly exploring potential futures of social-ecological systems through scenario planning, but this process often lacks quantitative response modeling and validation procedures. Simulation models are well placed to provide added rigor to scenario planning because of their ability to reproduce complex system dynamics, but the scenarios and management options explored in simulations are often not developed by stakeholders, and there is not a clear consensus on how to include climate model outputs. We see these strengths and weaknesses as complementarities and offer an analytical framework for integrating these three tools. We then describe the ways in which this framework can help shift climate change research from useful to usable.

  16. Impact of design research on industrial practice tools, technology, and training

    CERN Document Server

    Lindemann, Udo

    2016-01-01

    Showcasing exemplars of how various aspects of design research were successfully transitioned into and influenced, design practice, this book features chapters written by eminent international researchers and practitioners from industry on the Impact of Design Research on Industrial Practice. Chapters written by internationally acclaimed researchers of design analyse the findings (guidelines, methods and tools), technologies/products and educational approaches that have been transferred as tools, technologies and people to transform industrial practice of engineering design, whilst the chapters that are written by industrial practitioners describe their experience of how various tools, technologies and training impacted design practice. The main benefit of this book, for educators, researchers and practitioners in (engineering) design, will be access to a comprehensive coverage of case studies of successful transfer of outcomes of design research into practice; as well as guidelines and platforms for successf...

  17. iPat: Intelligent Prediction and Association Tool for Genomic Research.

    Science.gov (United States)

    Chen, Chunpeng James; Zhang, Zhiwu

    2018-01-11

    The ultimate goal of genomic research is to effectively predict phenotypes from genotypes so that medical management can improve human health and molecular breeding can increase agricultural production. Genomic prediction or selection (GS) plays a complementary role to genome-wide association studies (GWAS), which is the primary method to identify genes underlying phenotypes. Unfortunately, most computing tools cannot perform data analyses for both GWAS and GS. Furthermore, the majority of these tools are executed through a command-line interface (CLI), which requires programming skills. Non-programmers struggle to use them efficiently because of the steep learning curves and zero tolerance for data formats and mistakes when inputting keywords and parameters. To address these problems, this study developed a software package, named the Intelligent Prediction and Association Tool (iPat), with a user-friendly graphical user interface (GUI). With iPat, GWAS or GS can be performed using a pointing device to simply drag and/or click on graphical elements to specify input data files, choose input parameters, and select analytical models. Models available to users include those implemented in third party CLI packages such as GAPIT, PLINK, FarmCPU, BLINK, rrBLUP, and BGLR. Users can choose any data format and conduct analyses with any of these packages. File conversions are automatically conducted for specified input data and selected packages. A GWAS-assisted genomic prediction method was implemented to perform genomic prediction using any GWAS method such as FarmCPU. iPat was written in Java for adaptation to multiple operating systems including Windows, Mac, and Linux. The iPat executable file, user manual, tutorials, and example datasets are freely available at http://zzlab.net/iPat. Zhiwu.Zhang@WSU.edu. Supplementary data are available at Bioinformatics online. © The Author (2018). Published by Oxford University Press. All rights reserved. For Permissions, please

  18. A prospective observational study of machine translation software to overcome the challenge of including ethnic diversity in healthcare research.

    Science.gov (United States)

    Taylor, Rachel M; Crichton, Nicola; Moult, Beki; Gibson, Faith

    2015-04-01

    This study investigates whether machine translation could help with the challenge of enabling the inclusion of ethnic diversity in healthcare research. A two phase, prospective observational study. Two machine translators, Google Translate and Babylon 9, were tested. Translation of the Strengths and Difficulties Questionnaire (SDQ) from 24 languages into English and translation of an English information sheet into Spanish and Chinese were quality scored. Quality was assessed using the Translation Assessment Quality Tool. Only six of the 48 translations of the SDQ were rated as acceptable, all from Google Translate. The mean number of acceptably translated sentences was higher ( P  = 0·001) for Google Translate 17·1 (sd 7·2) than for Babylon 9 11 (sd 7·9). Translation by Google Translate was better for Spanish and Chinese, although no score was in the acceptable range. Machine translation is not currently sufficiently accurate without editing to provide translation of materials for use in healthcare research.

  19. miRQuest: integration of tools on a Web server for microRNA research.

    Science.gov (United States)

    Aguiar, R R; Ambrosio, L A; Sepúlveda-Hermosilla, G; Maracaja-Coutinho, V; Paschoal, A R

    2016-03-28

    This report describes the miRQuest - a novel middleware available in a Web server that allows the end user to do the miRNA research in a user-friendly way. It is known that there are many prediction tools for microRNA (miRNA) identification that use different programming languages and methods to realize this task. It is difficult to understand each tool and apply it to diverse datasets and organisms available for miRNA analysis. miRQuest can easily be used by biologists and researchers with limited experience with bioinformatics. We built it using the middleware architecture on a Web platform for miRNA research that performs two main functions: i) integration of different miRNA prediction tools for miRNA identification in a user-friendly environment; and ii) comparison of these prediction tools. In both cases, the user provides sequences (in FASTA format) as an input set for the analysis and comparisons. All the tools were selected on the basis of a survey of the literature on the available tools for miRNA prediction. As results, three different cases of use of the tools are also described, where one is the miRNA identification analysis in 30 different species. Finally, miRQuest seems to be a novel and useful tool; and it is freely available for both benchmarking and miRNA identification at http://mirquest.integrativebioinformatics.me/.

  20. What’s Ketso? A Tool for Researchers, Educators, and Practitioners

    Directory of Open Access Journals (Sweden)

    James S. Bates

    2016-06-01

    Full Text Available Researchers, educators, and practitioners utilize a range of tools and techniques to obtain data, input, feedback, and information from research participants, program learners, and stakeholders. Ketso is both an array of information gathering techniques and a toolkit (see www.ketso.com. It “can be used in any situation when people come together to share information, learn from each other, make decisions and plan actions” (Tippett & How, 2011, p. 4. The word ketso means “action” in the Sesotho language, spoken in the African nation of Lesotho where the concept for this instrument was conceived. Ketso techniques fall into the participatory action research family of social science research methods (Tippett, Handley, & Ravetz, 2007. Ohio State University Extension professionals have used the Ketso toolkit and its techniques in numerous settings, including for professional development, conducting community needs/interests assessments, brainstorming, and data collection. As a toolkit, Ketso uses tactile and colorful leaves, branches, and icons to organize and display participants’ contributions on felt mats. As an array of techniques, Ketso is effective in engaging audiences because it is inclusive and provides each participant a platform for their perspective to be shared.

  1. Including People with Dementia in Research: An Analysis of Australian Ethical and Legal Rules and Recommendations for Reform.

    Science.gov (United States)

    Ries, Nola M; Thompson, Katie A; Lowe, Michael

    2017-09-01

    Research is crucial to advancing knowledge about dementia, yet the burden of the disease currently outpaces research activity. Research often excludes people with dementia and other cognitive impairments because researchers and ethics committees are concerned about issues related to capacity, consent, and substitute decision-making. In Australia, participation in research by people with cognitive impairment is governed by a national ethics statement and a patchwork of state and territorial laws that have widely varying rules. We contend that this legislative variation precludes a consistent approach to research governance and participation and hinders research that seeks to include people with impaired capacity. In this paper, we present key ethical principles, provide a comprehensive review of applicable legal rules in Australian states and territories, and highlight significant differences and ambiguities. Our analysis includes recommendations for reform to improve clarity and consistency in the law and reduce barriers that may exclude persons with dementia from participating in ethically approved research. Our recommendations seek to advance the national decision-making principles recommended by the Australian Law Reform Commission, which emphasize the rights of all adults to make their own decisions and for those with impaired capacity to have access to appropriate supports to help them make decisions that affect their lives.

  2. Tracer-tracer relations as a tool for research on polar ozone loss

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, Rolf

    2010-07-01

    The report includes the following chapters: (1) Introduction: ozone in the atmosphere, anthropogenic influence on the ozone layer, polar stratospheric ozone loss; (2) Tracer-tracer relations in the stratosphere: tracer-tracer relations as a tool in atmospheric research; impact of cosmic-ray-induced heterogeneous chemistry on polar ozone; (3) quantifying polar ozone loss from ozone-tracer relations: principles of tracer-tracer correlation techniques; reference ozone-tracer relations in the early polar vortex; impact of mixing on ozone-tracer relations in the polar vortex; impact of mesospheric intrusions on ozone-tracer relations in the stratospheric polar vortex calculation of chemical ozone loss in the arctic in March 2003 based on ILAS-II measurements; (4) epilogue.

  3. URSSA, the Undergraduate Research Student Self-Assessment: A Tool for Assessing Student Outcomes of Undergraduate Research

    Science.gov (United States)

    Laursen, S. L.; Hunter, A.; Weston, T.; Thiry, H.

    2009-12-01

    Evidence-based thinking is essential both to science and to the development of effective educational programs. Thus assessment of student learning—gathering evidence about the nature and depth of students’ learning gains, and about how they arise—is a centerpiece of any effective undergraduate research (UR) program. Assessment data can be used to monitor progress, to diagnose problems, to strengthen program designs, and to report both good outcomes and strategies to improve them to institutional and financial stakeholders in UR programs. While the positive impact of UR on students’ educational, personal and professional development has long been a matter of faith, only recently have researchers and evaluators developed an empirical basis by which to identify and explain these outcomes. Based on this growing body of evidence, URSSA, the Undergraduate Research Student Self-Assessment, is a survey tool that departments and programs can use to assess student outcomes of UR. URSSA focuses on what students learn from their UR experience, rather than whether they liked it. Both multiple-choice and open-ended items focus on students’ gains from UR, including: (1) skills such as lab work and communication; (2) conceptual knowledge and linkages among ideas in their field and with other fields; (3) deepened understanding of the intellectual and practical work of science; (4) growth in confidence and adoption of the identity of scientist; (5) preparation for a career or graduate school in science; and (6) greater clarity in understanding what career or educational path they might wish to pursue. Other items probe students’ participation in important activities that have been shown to lead to these gains; and a set of optional items can be included to probe specific program features that may supplement UR (e.g. field trips, career seminars, housing arrangements). The poster will describe URSSA's content, development, validation, and use. For more information about

  4. Research integrity: catalyst and outcome of innovative research practices and tools

    OpenAIRE

    Kramer, Bianca; Bosman, Jeroen

    2017-01-01

    Presentation at WRCI2017 - session "Publishing and research ethics as wicked problems" In a world of changing research practices, three goals for science and scholarship can be identified: making research more open, efficient and ‘good’. The latter category involves research integrity, fair credit, transparency and reproducibility, and is potentially the most transformative for the way research currently is conducted. Open sharing in all phases of the research cycle is necessary, but not suff...

  5. Are EM's communication tools effective? Evaluation research of two EM publications

    International Nuclear Information System (INIS)

    Wight, Evelyn; Gardner, Gene; Harvey, Tony

    1992-01-01

    As a reflection of its growing culture of openness, and in response to the public's need for accurate information about its activities, the U.S. Department of Energy (DOE) Office of the Assistant Secretary for Environmental Restoration and Waste Management (EM) has increased the amount of information available to the public through communication tools such as brochures, fact sheets, and a travelling exhibit with an interactive computer display. Our involvement with this effort has been to design, develop, and critique booklets, brochures, fact sheets and other communication tools for EM. This paper presents an evaluation of the effectiveness of two communication tools we developed: the EM Booklet and the EM Fact Sheets. We measured effectiveness using non-parametric testing. This paper describes DOE's culture change, EM's communication tools and their context within DOE'S new open culture, our research, test methods and results, the significance of our research, and our plans for future research. (author)

  6. Studies and analyses of the management of scientific research and development, including implementation and application at NASA centers

    Science.gov (United States)

    Rubenstein, A. H.

    1975-01-01

    Summary results obtained through the Program of Research on the Management of Research and Development (POMRAD) were presented. The nature of the overall program and the specific projects undertaken were described. Statistical data is also given concerning the papers, publications, people, and major program areas associated with the program. The actual list of papers, names of doctoral and masters theses, and other details of the program are included as appendices.

  7. The Prospect of Neutron Scattering in the 21st Century: a Powerful Tool for Materials Research

    OpenAIRE

    Kartini, E

    2007-01-01

    Over the last 60 years research reactors (RRs) have played an important role in technological and socio-economical development of mankind, such as radioisotope production for medicine, industry, research and education. Neutron scattering has been widely used for research and development in materials science. The prospect of neutron scattering as a powerful tool for materials research is increasing in the 21st century. This can be seen from the investment of several new neutron sources all ove...

  8. Capacity-to-Consent in Psychiatric Research: Development and Preliminary Testing of a Screening Tool

    Science.gov (United States)

    Zayas, Luis H.; Cabassa, Leopoldo J.; Perez, M. Carmela

    2005-01-01

    Objective: Assuring research participants' capacity to provide informed consent has become increasingly important in health and mental health research, and each study faces unique capacity-assessment challenges, possibly requiring its own screening tool. This article describes the development and preliminary testing of a capacity-to-consent tool…

  9. Ethical Review as a Tool for Enhancing Postgraduate Supervision and Research Outcomes in the Creative Arts

    Science.gov (United States)

    Romano, Angela

    2016-01-01

    This article outlines the potential for Research Higher Degree (RHD) supervisors at universities and similar institutions to use ethical review as a constructive, dynamic tool in guiding RHD students in the timely completion of effective, innovative research projects. Ethical review involves a bureaucratized process for checking that researchers…

  10. New Tools for New Literacies Research: An Exploration of Usability Testing Software

    Science.gov (United States)

    Asselin, Marlene; Moayeri, Maryam

    2010-01-01

    Competency in the new literacies of the Internet is essential for participating in contemporary society. Researchers studying these new literacies are recognizing the limitations of traditional methodological tools and adapting new technologies and new media for use in research. This paper reports our exploration of usability testing software to…

  11. Action Research on a WebQuest as an Instructional Tool for Writing Abstracts of Research Articles

    Directory of Open Access Journals (Sweden)

    Krismiyati Latuperissa

    2012-08-01

    Full Text Available The massive growth of and access to information technology (IT has enabled the integration of technology into classrooms. One such integration is the use of WebQuests as an instructional tool in teaching targeted learning activities such as writing abstracts of research articles in English for English as a Foreign Language (EFL learners. In the academic world, writing an abstract of a research paper or final project in English can be challenging for EFL students. This article presents an action research project on the process and outcomes of using a WebQuest designed to help 20 Indonesian university IT students write a research article’s abstract in English. Findings reveal that despite positive feedback, changes need to be made to make the WebQuest a more effective instructional tool for the purpose it was designed.

  12. Including limitations in news coverage of cancer research: effects of news hedging on fatalism, medical skepticism, patient trust, and backlash.

    Science.gov (United States)

    Jensen, Jakob D; Carcioppolo, Nick; King, Andy J; Bernat, Jennifer K; Davis, LaShara; Yale, Robert; Smith, Jessica

    2011-05-01

    Past research has demonstrated that news coverage of cancer research, and scientific research generally, rarely contains discourse-based hedging, including caveats, limitations, and uncertainties. In a multiple message experiment (k = 4 news stories, N = 1082), the authors examined whether hedging shaped the perceptions of news consumers. The results revealed that participants were significantly less fatalistic about cancer (p = .039) and marginally less prone to nutritional backlash (p = .056) after exposure to hedged articles. Participants exposed to articles mentioning a second researcher (unaffiliated with the present study) exhibited greater trust in medical professions (p = .001). The findings provide additional support for the inclusion of discourse-based hedging in cancer news coverage and suggest that news consumers will use scientific uncertainty in illness representations.

  13. The Research-Teaching Nexus: Using a Construction Teaching Event as a Research Tool

    Science.gov (United States)

    Casanovas-Rubio, Maria del Mar; Ahearn, Alison; Ramos, Gonzalo; Popo-Ola, Sunday

    2016-01-01

    In principle, the research-teaching nexus should be seen as a two-way link, showing not only ways in which research supports teaching but also ways in which teaching supports research. In reality, the discussion has been limited almost entirely to the first of these practices. This paper presents a case study in which some student field-trip…

  14. Scientific Mobility and International Research Networks: Trends and Policy Tools for Promoting Research Excellence and Capacity Building

    Science.gov (United States)

    Jacob, Merle; Meek, V. Lynn

    2013-01-01

    One of the ways in which globalization is manifesting itself in higher education and research is through the increasing importance and emphasis on scientific mobility. This article seeks to provide an overview and analysis of current trends and policy tools for promoting mobility. The article argues that the mobility of scientific labour is an…

  15. Soil and Water Assessment Tool: Historical Development, Applications, and Future Research Directions, The

    OpenAIRE

    Philip W. Gassman; Manuel R. Reyes; Colleen H. Green; Jeffrey G. Arnold

    2007-01-01

    The Soil and Water Assessment Tool (SWAT) model is a continuation of nearly 30 years of modeling efforts conducted by the U.S. Department of Agriculture (USDA), Agricultural Research Service. SWAT has gained international acceptance as a robust interdisciplinary watershed modeling tool, as evidenced by international SWAT conferences, hundreds of SWAT-related papers presented at numerous scientific meetings, and dozens of articles published in peer-reviewed journals. The model has also been ad...

  16. Experimental research on the durability cutting tools for cutting-off steel profiles

    Directory of Open Access Journals (Sweden)

    Cristea Alexandru

    2017-01-01

    Full Text Available The production lines used for manufacturing U-shaped profiles are very complex and they must have high productivity. One of the most important stages of the fabrication process is the cutting-off. This paper presents the experimental research and analysis of the durability of the cutting tools used for cutting-off U-shaped metal steel profiles. The results of this work can be used to predict the durability of the cutting tools.

  17. Interactive Data Visualization for HIV Cohorts: Leveraging Data Exchange Standards to Share and Reuse Research Tools.

    Directory of Open Access Journals (Sweden)

    Meridith Blevins

    Full Text Available To develop and disseminate tools for interactive visualization of HIV cohort data.If a picture is worth a thousand words, then an interactive video, composed of a long string of pictures, can produce an even richer presentation of HIV population dynamics. We developed an HIV cohort data visualization tool using open-source software (R statistical language. The tool requires that the data structure conform to the HIV Cohort Data Exchange Protocol (HICDEP, and our implementation utilized Caribbean, Central and South America network (CCASAnet data.This tool currently presents patient-level data in three classes of plots: (1 Longitudinal plots showing changes in measurements viewed alongside event probability curves allowing for simultaneous inspection of outcomes by relevant patient classes. (2 Bubble plots showing changes in indicators over time allowing for observation of group level dynamics. (3 Heat maps of levels of indicators changing over time allowing for observation of spatial-temporal dynamics. Examples of each class of plot are given using CCASAnet data investigating trends in CD4 count and AIDS at antiretroviral therapy (ART initiation, CD4 trajectories after ART initiation, and mortality.We invite researchers interested in this data visualization effort to use these tools and to suggest new classes of data visualization. We aim to contribute additional shareable tools in the spirit of open scientific collaboration and hope that these tools further the participation in open data standards like HICDEP by the HIV research community.

  18. A Tool for Measuring NASA's Aeronautics Research Progress Toward Planned Strategic Community Outcomes

    Science.gov (United States)

    Tahmasebi, Farhad; Pearce, Robert

    2016-01-01

    Description of a tool for portfolio analysis of NASA's Aeronautics research progress toward planned community strategic Outcomes is presented. For efficiency and speed, the tool takes advantage of a function developed in Excels Visual Basic for Applications. The strategic planning process for determining the community Outcomes is also briefly discussed. Stakeholder buy-in, partnership performance, progress of supporting Technical Challenges, and enablement forecast are used as the criteria for evaluating progress toward Outcomes. A few illustrative examples of using the tool are also presented.

  19. Direct numerical control of machine tools in a nuclear research center by the CAMAC system

    International Nuclear Information System (INIS)

    Zwoll, K.; Mueller, K.D.; Becks, B.; Erven, W.; Sauer, M.

    1977-01-01

    The production of mechanical parts in research centers can be improved by connecting several numerically controlled machine tools to a central process computer via a data link. The CAMAC Serial Highway with its expandable structure yields an economic and flexible system for this purpose. The CAMAC System also facilitates the development of modular components controlling the machine tools itself. A CAMAC installation controlling three different machine tools connected to a central computer (PDP11) via the CAMAC Serial Highway is described. Besides this application, part of the CAMAC hardware and software can also be used for a great variety of scientific experiments

  20. Breastfeeding and lactation research: exploring a tool to measure infant feeding patterns.

    Science.gov (United States)

    Noel-Weiss, Joy; Taljaard, Monica; Kujawa-Myles, Sonya

    2014-01-01

    Infant feeding categories, often referred to as breastfeeding definitions, form the basis to describe infant feeding patterns; especially, breastfeeding duration and degree of breastfeeding exclusivity. Researchers use a variety of algorithms and no validated tool exists to measure feeding patterns for research purposes. The goal of this research project was to develop and test a tool to measure patterns of infant feeding for breastfeeding and lactation research. We used a literature review, survey methods, and statistical analysis to develop and test this health measurement tool. The work was completed in three phases: 1) development of the tool; 2) assessment of content validity with a panel of experts; and 3) testing for inter-rater reliability by comparing the conclusions of 2 independent research assistants (RAs) and by comparing mothers' feeding diaries with the RAs' findings. For the third phase, an a priori analysis determined we needed to recruit 75 participants. Inclusion criteria were women who had given birth to a single healthy newborn, planned to breastfeed and were able to breastfeed freely, were able to read and write in English or French, were willing and able to maintain a weekly feeding diary for 6 weeks and to answer 6 English telephone questionnaires (twice within 24 hrs x 3 times over 6 months. To measure inter-rater reliability, we used intraclass correlation coefficient. THE FINAL TOOL, THE FEEDCAT TOOL, CONTAINS TWO PARTS: 1) questions asked to determine what and how the baby was fed and 2) a chart to indicate the feeding category for each time point and recall period. We recruited 75 breastfeeding mothers to measure inter-rater reliability. Inter-rater reliability for classification of feeding categories by the two RAs and for agreement between the RAs' findings at 1 month and mothers' diaries at 4 weeks indicated excellent agreement. We produced a feeding categories tool that can be used by researchers to describe the type, amount

  1. RESEARCH GATE SCORE AS AN ASSESSMENT TOOL OF THE STAFF PERFORMANCE IN RESEARCH INSTITUTIONS FROM REPUBLIC OF MOLDOVA

    Directory of Open Access Journals (Sweden)

    Dragoş CIMPOIEŞ

    2014-06-01

    Full Text Available The positioning of research institutions from Republic of Moldova through Research Gate score will be analyzed inthis paper. The aim of Research Gate score ranking is to help researchers and scientists to measure and leveragetheir standing within the scientific community. Research Gate provides the researchers with a metric that iscalculated based on how all of their research is received by their peers, not just the work that have been published.The Research Gate Score focuses on scientists, an ever-growing community of specialists. By opening up the idea ofwhat the research institutions can gain credit for and handing the power to evaluate it, the Research Gate Scoreputs reputation back into the hands of researchers. The Research Gate Score provides scientists and researchinstitutions with an alternate way to measure its reputation and performance. In this context, it is a useful tool forassessing the research activity of Moldovan universities, but also of comparing the research activity of universitiesfrom the Republic of Moldova with those from neighborhood countries.

  2. Understanding and teaching key concepts and tools of evidence-based medicine: perspectives of a clinician-researcher pharmaceutical physician.

    Science.gov (United States)

    Karagianis, Jamie

    2011-12-01

    Clinical practice benefits from research to inform good decision making. Evidence-based medicine (EBM) helps physicians integrate experience and individual expertise with the best evidence. Various philosophical concepts, including "primum non nocere," are balanced to achieve this. The tools of EBM, such as number needed to treat, are easy to calculate and to use. Other valuable tools include number needed to harm, attributable risk, and likelihood of being helped or harmed. It is also important to distinguish between relative risk and absolute risk to avoid drawing the wrong conclusions. With the right teaching techniques to grab attention and encourage active participation, real examples can be used to impart practical skills that the clinician can employ in translating research findings into something that helps the individual patient. Copyright © 2011 Elsevier HS Journals, Inc. All rights reserved.

  3. The Toronto Symptom Assessment System for Wounds: a new clinical and research tool.

    Science.gov (United States)

    Maida, Vincent; Ennis, Marguerite; Kuziemsky, Craig

    2009-10-01

    To formulate a patient-rated assessment tool that facilitates the measurement of pain and polysymptom distress directly related to all classes of wounds. A prospective observational study derived from a sequential case series of patients with advanced illness was carried out to determine the most common symptoms associated with wounds from 9 distinct classes (malignant, pressure ulcers, iatrogenic, traumatic, diabetic foot ulcers, venous ulcers, arterial ulcers, infections/inflammatory lesions, and ostomies). Ten wound-related symptoms were identified and used to create a patient-scored assessment tool. The Toronto Symptom Assessment System for Wounds (TSAS-W) was then developed and used in a pilot trial during which patients completed TSAS-W at baseline and 7 days later. Five hundred thirty-one patients either presented with wounds at baseline or developed them during the 24-month follow-up period. Patients affected by any type of wound were asked to report on the top 3 symptoms directly attributable to their wounds. The pilot trial of TSAS-W involved 103 wounds afflicting 83 sequential patients. The most prevalent wound-related symptoms included pain, exudation, odor, itching, bleeding, aesthetic concern, swelling, and mass and bulk effects from the wound and associated dressings; 78.6% of the TSAS-W assessments were carried out by the patient alone, 14.6% were carried out by the patient assisted by a caregiver, and 6.8% were carried out entirely by a caregiver. The summation of all 10 TSAS-W parameters, the global wound symptom distress score (GWSDS), resulted in a mean for all wounds of 34.47 at baseline and decreased to a mean of 28.40 at 7 days later. Cosmetic or aesthetic concern and/or distress was associated with the highest mean scores of all symptoms. Malignant wounds and wounds involving the perineum and genitalia were associated with the highest GWSDSs. The TSAS-W is a new tool for systematically assessing the degree of pain and polysymptom distress

  4. Rapid development of image analysis research tools: Bridging the gap between researcher and clinician with pyOsiriX.

    Science.gov (United States)

    Blackledge, Matthew D; Collins, David J; Koh, Dow-Mu; Leach, Martin O

    2016-02-01

    We present pyOsiriX, a plugin built for the already popular dicom viewer OsiriX that provides users the ability to extend the functionality of OsiriX through simple Python scripts. This approach allows users to integrate the many cutting-edge scientific/image-processing libraries created for Python into a powerful DICOM visualisation package that is intuitive to use and already familiar to many clinical researchers. Using pyOsiriX we hope to bridge the apparent gap between basic imaging scientists and clinical practice in a research setting and thus accelerate the development of advanced clinical image processing. We provide arguments for the use of Python as a robust scripting language for incorporation into larger software solutions, outline the structure of pyOsiriX and how it may be used to extend the functionality of OsiriX, and we provide three case studies that exemplify its utility. For our first case study we use pyOsiriX to provide a tool for smooth histogram display of voxel values within a user-defined region of interest (ROI) in OsiriX. We used a kernel density estimation (KDE) method available in Python using the scikit-learn library, where the total number of lines of Python code required to generate this tool was 22. Our second example presents a scheme for segmentation of the skeleton from CT datasets. We have demonstrated that good segmentation can be achieved for two example CT studies by using a combination of Python libraries including scikit-learn, scikit-image, SimpleITK and matplotlib. Furthermore, this segmentation method was incorporated into an automatic analysis of quantitative PET-CT in a patient with bone metastases from primary prostate cancer. This enabled repeatable statistical evaluation of PET uptake values for each lesion, before and after treatment, providing estaimes maximum and median standardised uptake values (SUVmax and SUVmed respectively). Following treatment we observed a reduction in lesion volume, SUVmax and SUVmed for

  5. Welfare assessment in porcine biomedical research – Suggestion for an operational tool

    DEFF Research Database (Denmark)

    Søndergaard, Lene Vammen; Dagnæs-Hansen, Frederik; Herskin, Mette S

    2011-01-01

    used for experimental purposes; and (2) the scientific outcome can be dependent upon the welfare state of the animals. In order to be able to quantify and control laboratory pig welfare, a practical tool is needed. The purpose of the present paper is to provide an overview of the current status...... of the extent of welfare assessment in pigs used in biomedical research and to suggest a welfare assessment standard for research facilities based on an exposition of ethological considerations relevant for the welfare of pigs in biomedical research. The tools for porcine welfare assessment presented suggest......In recent years, increasing interest in using the pig (Sus scrofa) for biomedical research has become evident. Today, the pig is considered an advantageous alternative animal model for various human diseases and conditions. However, even though a considerable amount of biomedical research has been...

  6. A Multidisciplinary Delphi Consensus-Based Checklist to Define Clinical Documentation Tools for Both Routine and Research Purposes

    Directory of Open Access Journals (Sweden)

    Cecilia Veraar

    2018-01-01

    Full Text Available Background: To the best of our knowledge, a strategic approach to define the contents of structured clinical documentation tools for both clinical routine patient care and research purposes has not been reported so far, although electronic health record will become more and more structured and detailed in the future. Objective: To achieve an interdisciplinary consensus on a checklist to be considered for the preparation of disease- and situation-specific clinical documentation tools. Methods: A 2-round Delphi consensus-based process was conducted both with 19 physicians of different disciplines and 14 students from Austria, Switzerland, and Germany. Agreement was defined as 80% or more positive votes of the participants. Results: The participants agreed that a working group should be set up for the development of structured disease- or situation-specific documentation tools (97% agreement. The final checklist included 4 recommendations concerning the setup of the working group, 12 content-related recommendations, and 3 general and technical recommendations (mean agreement [standard deviation] = 97.4% [4.0%], ranging from 84.2% to 100.0%. Discussion and Conclusion: In the future, disease- and situation-specific structured documentation tools will provide an important bridge between registries and electronic health records. Clinical documentation tools defined according to this Delphi consensus-based checklist will provide data for registries while serving as high-quality data acquisition tools in routine clinical care.

  7. JADE: a tool for medical researchers to explore adverse drug events using health claims data.

    Science.gov (United States)

    Edlinger, D; Sauter, S K; Rinner, C; Neuhofer, L M; Wolzt, M; Grossmann, W; Endel, G; Gall, W

    2014-01-01

    The objective of our project was to create a tool for physicians to explore health claims data with regard to adverse drug reactions. The Java Adverse Drug Event (JADE) tool should enable the analysis of prescribed drugs in connection with diagnoses from hospital stays. We calculated the number of days drugs were taken by using the defined daily doses and estimated possible interactions between dispensed drugs using the Austria Codex, a database including drug-drug interactions. The JADE tool was implemented using Java, R and a PostgreSQL database. Beside an overview of the study cohort which includes selection of gender and age groups, selected statistical methods like association rule learning, logistic regression model and the number needed to harm have been implemented. The JADE tool can support physicians during their planning of clinical trials by showing the occurrences of adverse drug events with population based information.

  8. A QUALITATIVE RESEARCH REGARDING THE MARKETING COMMUNICATION TOOLS USED IN THE ONLINE ENVIRONMENT

    Directory of Open Access Journals (Sweden)

    POP Nicolae Al.

    2011-07-01

    Full Text Available Starting from the meaning of the communication process in marketing, the authors try to identify its role in assuring the continuity of the management process in what concerns the relationships between all the partners of the company, on the long term. An emphasis is made on the role of online communication and its tools in relationship marketing. In order to validate some of the mentioned ideas the authors have chosen to undertake a qualitative marketing research among the managers of some Romanian tourism companies. The qualitative part of the study had as purpose the identification of the main tools which form the basis of the communication with the beneficiaries of the touristic services, of the way in which the companies use the online communication tools for attracting, keeping and developing the long term relationships with their customers in the virtual environment. The following tools have been analyzed: websites, email marketing campaigns, e-newsletters, online advertising, search engines, sponsored links, blogs, RSS feed, social networks, forums, online discussion groups, portals, infomediaries and instant messaging. The chosen investigation method was the selective survey, the research technique - explorative interrogation and the research instrument - semi structured detailed interview, based on a conversation guide. A very important fact is the classification resulted after the respondents were requested to mention the most efficient tools for attracting customers and for maintaining the relationships with them. Although the notoriety of the online marketing tools is high, there are some tools that are known by definition, but are not used at all or are not used correctly; or are not known by definition, but are used in practice. The authors contributed by validating a performing methodology of qualitative research, a study which will open new ways and means for making the online communication tools used for touristic services in

  9. TU-CD-304-11: Veritas 2.0: A Cloud-Based Tool to Facilitate Research and Innovation

    Energy Technology Data Exchange (ETDEWEB)

    Mishra, P; Patankar, A; Etmektzoglou, A; Svatos, M [Varian Medical Systems, Palo Alto, CA (United States); Lewis, J [Brigham and Women’s Hospital, Boston, MA (United States)

    2015-06-15

    Purpose: We introduce Veritas 2.0, a cloud-based, non-clinical research portal, to facilitate translation of radiotherapy research ideas to new delivery techniques. The ecosystem of research tools includes web apps for a research beam builder for TrueBeam Developer Mode, an image reader for compressed and uncompressed XIM files, and a trajectory log file based QA/beam delivery analyzer. Methods: The research beam builder can generate TrueBeam readable XML file either from scratch or from pre-existing DICOM-RT plans. DICOM-RT plan is first converted to XML format and then researcher can interactively modify or add control points to them. Delivered beam can be verified via reading generated images and analyzing trajectory log files. Image reader can read both uncompressed and HND-compressed XIM images. The trajectory log analyzer lets researchers plot expected vs. actual values and deviations among 30 mechanical axes. The analyzer gives an animated view of MLC patterns for the beam delivery. Veritas 2.0 is freely available and its advantages versus standalone software are i) No software installation or maintenance needed, ii) easy accessibility across all devices iii) seamless upgrades and iv) OS independence. Veritas is written using open-source tools like twitter bootstrap, jQuery, flask, and Python-based modules. Results: In the first experiment, an anonymized 7-beam DICOM-RT IMRT plan was converted to XML beam containing 1400 control points. kV and MV imaging points were inserted into this XML beam. In another experiment, a binary log file was analyzed to compare actual vs expected values and deviations among axes. Conclusions: Veritas 2.0 is a public cloud-based web app that hosts a pool of research tools for facilitating research from conceptualization to verification. It is aimed at providing a platform for facilitating research and collaboration. I am full time employee at Varian Medical systems, Palo Alto.

  10. TU-CD-304-11: Veritas 2.0: A Cloud-Based Tool to Facilitate Research and Innovation

    International Nuclear Information System (INIS)

    Mishra, P; Patankar, A; Etmektzoglou, A; Svatos, M; Lewis, J

    2015-01-01

    Purpose: We introduce Veritas 2.0, a cloud-based, non-clinical research portal, to facilitate translation of radiotherapy research ideas to new delivery techniques. The ecosystem of research tools includes web apps for a research beam builder for TrueBeam Developer Mode, an image reader for compressed and uncompressed XIM files, and a trajectory log file based QA/beam delivery analyzer. Methods: The research beam builder can generate TrueBeam readable XML file either from scratch or from pre-existing DICOM-RT plans. DICOM-RT plan is first converted to XML format and then researcher can interactively modify or add control points to them. Delivered beam can be verified via reading generated images and analyzing trajectory log files. Image reader can read both uncompressed and HND-compressed XIM images. The trajectory log analyzer lets researchers plot expected vs. actual values and deviations among 30 mechanical axes. The analyzer gives an animated view of MLC patterns for the beam delivery. Veritas 2.0 is freely available and its advantages versus standalone software are i) No software installation or maintenance needed, ii) easy accessibility across all devices iii) seamless upgrades and iv) OS independence. Veritas is written using open-source tools like twitter bootstrap, jQuery, flask, and Python-based modules. Results: In the first experiment, an anonymized 7-beam DICOM-RT IMRT plan was converted to XML beam containing 1400 control points. kV and MV imaging points were inserted into this XML beam. In another experiment, a binary log file was analyzed to compare actual vs expected values and deviations among axes. Conclusions: Veritas 2.0 is a public cloud-based web app that hosts a pool of research tools for facilitating research from conceptualization to verification. It is aimed at providing a platform for facilitating research and collaboration. I am full time employee at Varian Medical systems, Palo Alto

  11. A preliminary report on the initiation of a clinical research program in an orthopaedic surgery department: roadmaps and tool kits.

    Science.gov (United States)

    Merwin, Sara L; Fornari, Alice; Lane, Lewis B

    2014-01-01

    A formal research program enhances resident training experience, productivity and hones critical appraisal skills. This initiative sought to investigate if an academic orthopaedic surgery department could implement a clinical research program, with the goal of increasing resident scholarly activity, a requirement of the Resident Review Committee, and achieve a parallel aim of enhancing the research focus of faculty. A multifaceted intervention including a needs assessment, appropriation of dedicated research staffing, development of tracking tools and policies, and a formalized research curriculum, followed by additional research time for residents was planned and implemented. The impact of all of these efforts is measured with specific outcomes, pre and post implementation. The North Shore-LIJ Orthopaedic Surgery Department is a high volume clinical and education program with 17 fulltime core faculty and 18 residents at 2 tertiary hospitals. Residents were the focus of the intervention. The participation of faculty as principal investigators and sponsors was a key component to ensure success. The following outcomes were observed post intervention: increases in institutionally-required research training for faculty/residents, number of IRB protocols submitted, abstracts submitted to national meetings, percentage of time faculty report they spend on research activities, additional hours allocated to the new Department sponsored research curriculum and an additional research rotation for trainees. The official inception of a formalized program (2012) with a structured research process, invigorated faculty and trainees to formulate clinical research inquiries, generate hypotheses, create protocols and design and implement protocols. Structured tools, an experienced clinical research "champion" and commitment from departmental leadership were demonstrated as effective in transforming the focus of a clinical department into one with a nascent clinical research program

  12. SMART II : the spot market agent research tool version 2.0.

    Energy Technology Data Exchange (ETDEWEB)

    North, M. J. N.

    2000-12-14

    Argonne National Laboratory (ANL) has worked closely with Western Area Power Administration (Western) over many years to develop a variety of electric power marketing and transmission system models that are being used for ongoing system planning and operation as well as analytic studies. Western markets and delivers reliable, cost-based electric power from 56 power plants to millions of consumers in 15 states. The Spot Market Agent Research Tool Version 2.0 (SMART II) is an investigative system that partially implements some important components of several existing ANL linear programming models, including some used by Western. SMART II does not implement a complete model of the Western utility system but it does include several salient features of this network for exploratory purposes. SMART II uses a Swarm agent-based framework. SMART II agents model bulk electric power transaction dynamics with recognition for marginal costs as well as transmission and generation constraints. SMART II uses a sparse graph of nodes and links to model the electric power spot market. The nodes represent power generators and consumers with distinct marginal decision curves and varying investment capital as well individual learning parameters. The links represent transmission lines with individual capacities taken from a range of central distribution, outlying distribution and feeder line types. The application of SMART II to electric power systems studies has produced useful results different from those often found using more traditional techniques. Use of the advanced features offered by the Swarm modeling environment simplified the creation of the SMART II model.

  13. Incorporating ethical principles into clinical research protocols: a tool for protocol writers and ethics committees.

    Science.gov (United States)

    Li, Rebecca H; Wacholtz, Mary C; Barnes, Mark; Boggs, Liam; Callery-D'Amico, Susan; Davis, Amy; Digilova, Alla; Forster, David; Heffernan, Kate; Luthin, Maeve; Lynch, Holly Fernandez; McNair, Lindsay; Miller, Jennifer E; Murphy, Jacquelyn; Van Campen, Luann; Wilenzick, Mark; Wolf, Delia; Woolston, Cris; Aldinger, Carmen; Bierer, Barbara E

    2016-04-01

    A novel Protocol Ethics Tool Kit ('Ethics Tool Kit') has been developed by a multi-stakeholder group of the Multi-Regional Clinical Trials Center of Brigham and Women's Hospital and Harvard. The purpose of the Ethics Tool Kit is to facilitate effective recognition, consideration and deliberation of critical ethical issues in clinical trial protocols. The Ethics Tool Kit may be used by investigators and sponsors to develop a dedicated Ethics Section within a protocol to improve the consistency and transparency between clinical trial protocols and research ethics committee reviews. It may also streamline ethics review and may facilitate and expedite the review process by anticipating the concerns of ethics committee reviewers. Specific attention was given to issues arising in multinational settings. With the use of this Tool Kit, researchers have the opportunity to address critical research ethics issues proactively, potentially speeding the time and easing the process to final protocol approval. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  14. Quantitative Risk reduction estimation Tool For Control Systems, Suggested Approach and Research Needs

    Energy Technology Data Exchange (ETDEWEB)

    Miles McQueen; Wayne Boyer; Mark Flynn; Sam Alessi

    2006-03-01

    For the past year we have applied a variety of risk assessment technologies to evaluate the risk to critical infrastructure from cyber attacks on control systems. More recently, we identified the need for a stand alone control system risk reduction estimation tool to provide owners and operators of control systems with a more useable, reliable, and credible method for managing the risks from cyber attack. Risk is defined as the probability of a successful attack times the value of the resulting loss, typically measured in lives and dollars. Qualitative and ad hoc techniques for measuring risk do not provide sufficient support for cost benefit analyses associated with cyber security mitigation actions. To address the need for better quantitative risk reduction models we surveyed previous quantitative risk assessment research; evaluated currently available tools; developed new quantitative techniques [17] [18]; implemented a prototype analysis tool to demonstrate how such a tool might be used; used the prototype to test a variety of underlying risk calculational engines (e.g. attack tree, attack graph); and identified technical and research needs. We concluded that significant gaps still exist and difficult research problems remain for quantitatively assessing the risk to control system components and networks, but that a useable quantitative risk reduction estimation tool is not beyond reach.

  15. Health systems research training as a tool for more effective Hansen's disease control programmes in Brazil.

    Science.gov (United States)

    Ramos, Alberto Novaes; Heukelbach, Jorg; Gomide, Marcia; Hinders, Duane C; Schreuder, Pieter A M

    2006-09-01

    In Brazil, Hansen's disease (HD) is still a public health problem. Although much progress has been made in Hansen's disease control (HDC) at all levels of government over the past 20 years, efforts have been hampered by information gaps related to specific areas of the disease, exacerbated by an absence of appropriate evaluation instruments and routine systematic analysis. Health Systems Research (HSR) aims to collect the necessary data to provide the most relevant information to policy makers and health managers to take more informed decisions. In Brazil, four HSR courses on HDC were organized by two non-governmental organizations (NGOs), Netherlands Leprosy Relief (NLR) and the British Leprosy Relief Association (LEPRA) between 2001 and 2005. Key personnel working in HDC from various states were invited to participate in the courses. The research proposals were developed during an HSR workshop and carried out in the field. The research topics of the projects included the following: the integration of HDC programmes into the primary health care system; the high percentage of the new patients diagnosed and treated at state referral centres; the psychological and social impact of surgical rehabilitation; the efficacy of neurolysis; the quality of the national health information system and the effectiveness of new case detection and health education campaigns. Following the completion of the field work, the data were analysed and a research report written. The results and recommendations were later presented to key stakeholders and policy makers in the states. Practical outcomes of the HSR courses include the drafting of new HDC guidelines; improvement of health information system databases and the revision of epidemiological data. These results have been presented at national and international congresses and published in peer-reviewed jornals. HSR has had a positive impact on the working routines of trainees through the process of learning the research methodology

  16. Quality Assessment of Research Articles in Nuclear Medicine Using STARD and QUADAS-2 Tools

    International Nuclear Information System (INIS)

    Roysri, Krisana; Chotipanich, Chanisa; Laopaiboon, Vallop; Khiewyoo, Jiraporn

    2014-01-01

    Diagnostic nuclear medicine is being increasingly employed in clinical practice with the advent of new technologies and radiopharmaceuticals. The report of the prevalence of a certain disease is important for assessing the quality of that article. Therefore, this study was performed to evaluate the quality of published nuclear medicine articles and determine the frequency of reporting the prevalence of studied diseases. We used Standards for Reporting of Diagnostic Accuracy (STARD) and Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) checklists for evaluating the quality of articles published in five nuclear medicine journals with the highest impact factors in 2012. The articles were retrieved from Scopus database and were selected and assessed independently by two nuclear medicine physicians. Decision concerning equivocal data was made by consensus between the reviewers. The average STARD score was approximately 17 points, and the highest score was 17.19±2.38 obtained by the European Journal of Nuclear Medicine. QUADAS-2 tool showed that all journals had low bias regarding study population. The Journal of Nuclear Medicine had the highest score in terms of index test, reference standard, and time interval. Lack of clarity regarding the index test, reference standard, and time interval was frequently observed in all journals including Clinical Nuclear Medicine, in which 64% of the studies were unclear regarding the index test. Journal of Nuclear Cardiology had the highest number of articles with appropriate reference standard (83.3%), though it had the lowest frequency of reporting disease prevalence (zero reports). All five journals had the same STARD score, while index test, reference standard, and time interval were very unclear according to QUADAS-2 tool. Unfortunately, data were too limited to determine which journal had the lowest risk of bias. In fact, it is the author's responsibility to provide details of research methodology so that the

  17. Quality Assessment of Research Articles in Nuclear Medicine Using STARD and QUADAS-2 Tools.

    Science.gov (United States)

    Roysri, Krisana; Chotipanich, Chanisa; Laopaiboon, Vallop; Khiewyoo, Jiraporn

    2014-01-01

    Diagnostic nuclear medicine is being increasingly employed in clinical practice with the advent of new technologies and radiopharmaceuticals. The report of the prevalence of a certain disease is important for assessing the quality of that article. Therefore, this study was performed to evaluate the quality of published nuclear medicine articles and determine the frequency of reporting the prevalence of studied diseases. We used Standards for Reporting of Diagnostic Accuracy (STARD) and Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) checklists for evaluating the quality of articles published in five nuclear medicine journals with the highest impact factors in 2012. The articles were retrieved from Scopus database and were selected and assessed independently by two nuclear medicine physicians. Decision concerning equivocal data was made by consensus between the reviewers. The average STARD score was approximately 17 points, and the highest score was 17.19±2.38 obtained by the European Journal of Nuclear Medicine. QUADAS-2 tool showed that all journals had low bias regarding study population. The Journal of Nuclear Medicine had the highest score in terms of index test, reference standard, and time interval. Lack of clarity regarding the index test, reference standard, and time interval was frequently observed in all journals including Clinical Nuclear Medicine, in which 64% of the studies were unclear regarding the index test. Journal of Nuclear Cardiology had the highest number of articles with appropriate reference standard (83.3%), though it had the lowest frequency of reporting disease prevalence (zero reports). All five journals had the same STARD score, while index test, reference standard, and time interval were very unclear according to QUADAS-2 tool. Unfortunately, data were too limited to determine which journal had the lowest risk of bias. In fact, it is the author's responsibility to provide details of research methodology so that the reader

  18. Medical Informatics: An Essential Tool for Health Sciences Research in Acute Care

    Directory of Open Access Journals (Sweden)

    Man Li

    2009-10-01

    Full Text Available Medical Informatics has become an important tool in modern health care practice and research. In the present article we outline the challenges and opportunities associated with the implementation of electronic medical records (EMR in complex environments such as intensive care units (ICU. We share our initial experience in the design, maintenance and application of a customized critical care, Microsoft SQL based, research warehouse, ICU DataMart. ICU DataMart integrates clinical and administrative data from heterogeneous sources within the EMR to support research and practice improvement in the ICUs. Examples of intelligent alarms – “sniffers”, administrative reports, decision support and clinical research applications are presented.

  19. Medical informatics: an essential tool for health sciences research in acute care.

    Science.gov (United States)

    Li, Man; Pickering, Brian W; Smith, Vernon D; Hadzikadic, Mirsad; Gajic, Ognjen; Herasevich, Vitaly

    2009-10-01

    Medical Informatics has become an important tool in modern health care practice and research. In the present article we outline the challenges and opportunities associated with the implementation of electronic medical records (EMR) in complex environments such as intensive care units (ICU). We share our initial experience in the design, maintenance and application of a customized critical care, Microsoft SQL based, research warehouse, ICU DataMart. ICU DataMart integrates clinical and administrative data from heterogeneous sources within the EMR to support research and practice improvement in the ICUs. Examples of intelligent alarms -- "sniffers", administrative reports, decision support and clinical research applications are presented.

  20. Web-based management of research groups - using the right tools and an adequate integration strategy

    International Nuclear Information System (INIS)

    Barroso, Antonio Carlos de Oliveira; Menezes, Mario Olimpio de

    2011-01-01

    Nowadays broad interest in a couple of inter linked subject areas can make the configuration of a research group to be much diversified both in terms of its components and of the binding relationships that glues the group together. That is the case of the research group for knowledge management and its applications to nuclear technology - KMANT at IPEN, a living entity born 7 years ago and that has sustainably attracted new collaborators. This paper describes the strategic planning of the group, its charter and credo, the present components of the group and the diversified nature of their relations with the group and with IPEN. Then the technical competencies and currently research lines (or programs) are described as well as the research projects, and the management scheme of the group. In the sequence the web-based management and collaboration tools are described as well our experience with their use. KMANT have experiment with over 20 systems and software in this area, but we will focus on those aimed at: (a) web-based project management (RedMine, ClockinIT, Who does, PhProjekt and Dotproject); (b) teaching platform (Moodle); (c) mapping and knowledge representation tools (Cmap, Freemind and VUE); (d) Simulation tools (Matlab, Vensim and NetLogo); (e) social network analysis tools (ORA, MultiNet and UciNet); (f) statistical analysis and modeling tools (R and SmartPLS). Special emphasis is given to the coupling of the group permanent activities like graduate courses and regular seminars and how newcomers are selected and trained to be able to enroll the group. A global assessment of the role the management strategy and available tool set for the group performance is presented. (author)

  1. Web-based management of research groups - using the right tools and an adequate integration strategy

    Energy Technology Data Exchange (ETDEWEB)

    Barroso, Antonio Carlos de Oliveira; Menezes, Mario Olimpio de, E-mail: barroso@ipen.b, E-mail: mario@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil). Grupo de Pesquisa em Gestao do Conhecimento Aplicada a Area Nuclear

    2011-07-01

    Nowadays broad interest in a couple of inter linked subject areas can make the configuration of a research group to be much diversified both in terms of its components and of the binding relationships that glues the group together. That is the case of the research group for knowledge management and its applications to nuclear technology - KMANT at IPEN, a living entity born 7 years ago and that has sustainably attracted new collaborators. This paper describes the strategic planning of the group, its charter and credo, the present components of the group and the diversified nature of their relations with the group and with IPEN. Then the technical competencies and currently research lines (or programs) are described as well as the research projects, and the management scheme of the group. In the sequence the web-based management and collaboration tools are described as well our experience with their use. KMANT have experiment with over 20 systems and software in this area, but we will focus on those aimed at: (a) web-based project management (RedMine, ClockinIT, Who does, PhProjekt and Dotproject); (b) teaching platform (Moodle); (c) mapping and knowledge representation tools (Cmap, Freemind and VUE); (d) Simulation tools (Matlab, Vensim and NetLogo); (e) social network analysis tools (ORA, MultiNet and UciNet); (f) statistical analysis and modeling tools (R and SmartPLS). Special emphasis is given to the coupling of the group permanent activities like graduate courses and regular seminars and how newcomers are selected and trained to be able to enroll the group. A global assessment of the role the management strategy and available tool set for the group performance is presented. (author)

  2. MEDICAL INFORMATICS: AN ESSENTIAL TOOL FOR HEALTH SCIENCES RESEARCH IN ACUTE CARE

    OpenAIRE

    Li, Man; Pickering, Brian W.; Smith, Vernon D.; Hadzikadic, Mirsad; Gajic, Ognjen; Herasevich, Vitaly

    2009-01-01

    Medical Informatics has become an important tool in modern health care practice and research. In the present article we outline the challenges and opportunities associated with the implementation of electronic medical records (EMR) in complex environments such as intensive care units (ICU). We share our initial experience in the design, maintenance and application of a customized critical care, Microsoft SQL based, research warehouse, ICU DataMart. ICU DataMart integrates clinical and adminis...

  3. Medical Informatics: An Essential Tool for Health Sciences Research in Acute Care

    OpenAIRE

    Man Li; Brian W. Pickering; Vernon D. Smith; Mirsad Hadzikadic; Ognjen Gajic; Vitaly Herasevich

    2009-01-01

    Medical Informatics has become an important tool in modern health care practice and research. In the present article we outline the challenges and opportunities associated with the implementation of electronic medical records (EMR) in complex environments such as intensive care units (ICU). We share our initial experience in the design, maintenance and application of a customized critical care, Microsoft SQL based, research warehouse, ICU DataMart. ICU DataMart integrates clinical and adminis...

  4. FUTISTREFFIT : Participatory Action Research: analysis and evaluation of football as a community youth development tool

    OpenAIRE

    Wesseh, Cucu

    2012-01-01

    Wesseh Cucu. Thesis: Futistreffit – analysis and evaluation. Language: English. Content: 53 pages, 2 appendices. Degree: Bachelor of Social Services. Focus: Community Development. Institution: Diaconia University of Applied Sciences, Järvenpää The aim of this research is to examine football as a positive youth development tool for Learning-Integration. It focuses on community youth work and uses action research as the prime method of analysis and evaluation. The subject of researc...

  5. The new alchemy: Online networking, data sharing and research activity distribution tools for scientists.

    Science.gov (United States)

    Williams, Antony J; Peck, Lou; Ekins, Sean

    2017-01-01

    There is an abundance of free online tools accessible to scientists and others that can be used for online networking, data sharing and measuring research impact. Despite this, few scientists know how these tools can be used or fail to take advantage of using them as an integrated pipeline to raise awareness of their research outputs. In this article, the authors describe their experiences with these tools and how they can make best use of them to make their scientific research generally more accessible, extending its reach beyond their own direct networks, and communicating their ideas to new audiences. These efforts have the potential to drive science by sparking new collaborations and interdisciplinary research projects that may lead to future publications, funding and commercial opportunities. The intent of this article is to: describe some of these freely accessible networking tools and affiliated products; demonstrate from our own experiences how they can be utilized effectively; and, inspire their adoption by new users for the benefit of science.

  6. Making Research Fly in Schools: "Drosophila" as a Powerful Modern Tool for Teaching Biology

    Science.gov (United States)

    Harbottle, Jennifer; Strangward, Patrick; Alnuamaani, Catherine; Lawes, Surita; Patel, Sanjai; Prokop, Andreas

    2016-01-01

    The "droso4schools" project aims to introduce the fruit fly "Drosophila" as a powerful modern teaching tool to convey curriculum-relevant specifications in biology lessons. Flies are easy and cheap to breed and have been at the forefront of biology research for a century, providing unique conceptual understanding of biology and…

  7. Scenarios as Research Tools for Investigating Social Issues. Studies in Educational Administration Number 45.

    Science.gov (United States)

    Small, Marlene B.; Briggs, Dora K.

    This paper describes an experiment in using the "scenario," a concept parallel to that of the case study, as a research tool for obtaining information about possible sex discrimination in personnel decisions by high school principals in South Australia. A review of the literature indicated that in spite of legislation aimed at…

  8. Current research relevant to the improvement of γ-ray spectroscopy as an analytical tool

    International Nuclear Information System (INIS)

    Meyer, R.A.; Tirsell, K.G.; Armantrout, G.A.

    1976-01-01

    Four areas of research that will have significant impact on the further development of γ-ray spectroscopy as an accurate analytical tool are considered. The areas considered are: (1) automation; (2) accurate multigamma ray sources; (3) accuracy of the current and future γ-ray energy scale, and (4) new solid state X and γ-ray detectors

  9. The styrene-maleic acid copolymer: : a versatile tool in membrane research

    NARCIS (Netherlands)

    Dörr, Jonas M; Scheidelaar, Stefan; Koorengevel, Martijn C; Dominguez Pardo, Juan; Schäfer, Marre; van Walree, Cornelis A; Killian, J Antoinette

    A new and promising tool in membrane research is the detergent-free solubilization of membrane proteins by styrene-maleic acid copolymers (SMAs). These amphipathic molecules are able to solubilize lipid bilayers in the form of nanodiscs that are bounded by the polymer. Thus, membrane proteins can be

  10. Handbook of Research on Science Education and University Outreach as a Tool for Regional Development

    Science.gov (United States)

    Narasimharao, B. Pandu, Ed.; Wright, Elizabeth, Ed.; Prasad, Shashidhara, Ed.; Joshi, Meghana, Ed.

    2017-01-01

    Higher education institutions play a vital role in their surrounding communities. Besides providing a space for enhanced learning opportunities, universities can utilize their resources for social and economic interests. The "Handbook of Research on Science Education and University Outreach as a Tool for Regional Development" is a…

  11. Theatre elicitation integrating a participatory research tool in a mixed-method study

    NARCIS (Netherlands)

    Roerig, S.; Evers, S.J.T.M.; Krabbendam, L.

    2015-01-01

    The relation between theatre, or drama, and research is not novel which is illustrated by concepts such as role theory, theatre for development, or distancing in drama therapy. In various scientific fields theatre is used as a communicative and/or educative tool, however in the realm of childhood

  12. Tools to Analyze Morphology and Spatially Mapped Molecular Data | Informatics Technology for Cancer Research (ITCR)

    Science.gov (United States)

    This project is to develop, deploy, and disseminate a suite of open source tools and integrated informatics platform that will facilitate multi-scale, correlative analyses of high resolution whole slide tissue image data, spatially mapped genetics and molecular data for cancer research. This platform will play an essential role in supporting studies of tumor initiation, development, heterogeneity, invasion, and metastasis.

  13. A Portfolio Analysis Tool for Measuring NASAs Aeronautics Research Progress toward Planned Strategic Outcomes

    Science.gov (United States)

    Tahmasebi, Farhad; Pearce, Robert

    2016-01-01

    Description of a tool for portfolio analysis of NASA's Aeronautics research progress toward planned community strategic Outcomes is presented. The strategic planning process for determining the community Outcomes is also briefly described. Stakeholder buy-in, partnership performance, progress of supporting Technical Challenges, and enablement forecast are used as the criteria for evaluating progress toward Outcomes. A few illustrative examples are also presented.

  14. Qualitative and Quantitative Management Tools Used by Financial Officers in Public Research Universities

    Science.gov (United States)

    Trexler, Grant Lewis

    2012-01-01

    This dissertation set out to identify effective qualitative and quantitative management tools used by financial officers (CFOs) in carrying out their management functions of planning, decision making, organizing, staffing, communicating, motivating, leading and controlling at a public research university. In addition, impediments to the use of…

  15. Characterization of a standardized glucagon challenge test as a pharmacodynamic tool in pharmacological research

    NARCIS (Netherlands)

    van Dongen, M. G. J.; Geerts, B. F.; Bhanot, S.; Morgan, E. S.; de Kam, M. L.; Moerland, M.; Romijn, J. A.; Cohen, A. F.; Burggraaf, J.

    2014-01-01

    The aim of this study was to characterize a glucagon challenge test as a tool in diabetes research by assessing the inter- and intra-individual variability, and investigating the activity of the autonomic nervous system (ANS) during the challenge, as this might have an indirect impact on glucose

  16. Building Bridges: The Use of Reflective Oral Diaries as a Qualitative Research Tool

    Science.gov (United States)

    Hewitt, Elizabeth

    2017-01-01

    The article is a reflection on the use of an oral diary as a qualitative research tool, the role that it played during fieldwork and the methodological issues that emerged. It draws on a small-scale empirical study into primary school teachers' use of group discussion, during which oral diaries were used to explore and document teacher reflective…

  17. Augmented reality as a tool for linguistic research: Intercepting and manipulating multimodal interaction

    OpenAIRE

    Pitsch, Karola; Neumann, Alexander; Schnier, Christian; Hermann, Thomas

    2013-01-01

    We suggest that an Augmented Reality (AR) system for coupled interaction partners provides a new tool for linguistic research that allows to manipulate the coparticipants’ real-time perception and action. It encompasses novel facilities for recording heterogeneous sensor-rich data sets to be accessed in parallel with qualitative/manual and quantitative/computational methods.

  18. Western land managers will need all available tools for adapting to climate change, including grazing: a critique of Beschta et al.

    Science.gov (United States)

    Svejcar, Tony; Boyd, Chad; Davies, Kirk; Madsen, Matthew; Bates, Jon; Sheley, Roger; Marlow, Clayton; Bohnert, David; Borman, Mike; Mata-Gonzàlez, Ricardo; Buckhouse, John; Stringham, Tamzen; Perryman, Barry; Swanson, Sherman; Tate, Kenneth; George, Mel; Ruyle, George; Roundy, Bruce; Call, Chris; Jensen, Kevin; Launchbaugh, Karen; Gearhart, Amanda; Vermeire, Lance; Tanaka, John; Derner, Justin; Frasier, Gary; Havstad, Kris

    2014-06-01

    In a previous article, Beschta et al. (Environ Manag 51(2):474-491, 2013) argue that grazing by large ungulates (both native and domestic) should be eliminated or greatly reduced on western public lands to reduce potential climate change impacts. The authors did not present a balanced synthesis of the scientific literature, and their publication is more of an opinion article. Their conclusions do not reflect the complexities associated with herbivore grazing. Because grazing is a complex ecological process, synthesis of the scientific literature can be a challenge. Legacy effects of uncontrolled grazing during the homestead era further complicate analysis of current grazing impacts. Interactions of climate change and grazing will depend on the specific situation. For example, increasing atmospheric CO₂ and temperatures may increase accumulation of fine fuels (primarily grasses) and thus increase wildfire risk. Prescribed grazing by livestock is one of the few management tools available for reducing fine fuel accumulation. While there are certainly points on the landscape where herbivore impacts can be identified, there are also vast grazed areas where impacts are minimal. Broad scale reduction of domestic and wild herbivores to help native plant communities cope with climate change will be unnecessary because over the past 20-50 years land managers have actively sought to bring populations of native and domestic herbivores in balance with the potential of vegetation and soils. To cope with a changing climate, land managers will need access to all available vegetation management tools, including grazing.

  19. Advancing institutional efforts to support research mentorship: a conceptual framework and self-assessment tool.

    Science.gov (United States)

    Keyser, Donna J; Lakoski, Joan M; Lara-Cinisomo, Sandraluz; Schultz, Dana J; Williams, Valerie L; Zellers, Darlene F; Pincus, Harold Alan

    2008-03-01

    The purpose of this article is to assist institutions in advancing their efforts to support research mentorship. The authors begin by describing how institutions can shape the key domains of research mentorship: (1) the criteria for selecting mentors, (2) incentives for motivating faculty to serve effectively as mentors, (3) factors that facilitate the mentor-mentee relationship, (4) factors that strengthen a mentee's ability to conduct research responsibly, and (5) factors that contribute to the professional development of both mentees and mentors. On the basis of a conceptual analysis of these domains as currently documented in the literature, as well as their collective experience examining mentoring programs at a range of academic medicine institutions and departments, the authors provide a framework that leaders of institutions and/or departments can adapt for use as a tool to document and monitor policies for guiding the mentorship process, the programs/activities through which these policies are implemented, and the structures that are responsible for maintaining policies and implementing programs. The authors provide an example of how one hypothetical institution might use the self-assessment tool to track its policies, programs, and structures across the key domains of research mentorship and, on the basis of this information, identify a range of potential actions to strengthen its research mentoring efforts. The authors conclude with a brief discussion of the limitations of the self-assessment tool, the potential drawbacks and benefits of the overall approach, and proposed next steps for research in this area.

  20. Development and implementation of a performance measure tool in an academic pediatric research network.

    Science.gov (United States)

    Stanley, Rachel; Lillis, Kathleen A; Zuspan, Sally Jo; Lichenstein, Richard; Ruddy, Richard M; Gerardi, Michael J; Dean, J Michael

    2010-09-01

    The Pediatric Emergency Care Applied Research Network (PECARN) is a federally funded multi-center research network. To promote high quality research within the network, it is important to establish evaluation tools to measure performance of the research sites. To describe the collaborative development of a site performance measure tool "report card" in an academic pediatric research network. To display report card template information and discuss the successes and challenges of the report cards. DEVELOPMENT AND IMPLEMENTATION OF THE NETWORK PERFORMANCE MEASURE TOOL: The PECARN Quality Assurance Subcommittee and the PECARN data center were responsible for the development and implementation of the report cards. Using a Balanced Scorecard format, four key metrics were identified to align with PECARN's research goals. Performance indicators were defined for each of these metrics. After two years of development, the final report cards have been implemented annually since 2005. Protocol submission time to the Institutional Review Board (IRB) improved between 2005 and 2007. Mean overall report card scores for site report cards increased during this period with less variance between highest and lowest performing sites indicating overall improvement. Report cards have helped PECARN sites and investigators focus on performance improvement and may have contributed to improved operations and efficiencies within the network. Copyright 2010 Elsevier Inc. All rights reserved.

  1. Using Digital Video as a Research Tool: Ethical Issues for Researchers

    Science.gov (United States)

    Schuck, Sandy; Kearney, Matthew

    2006-01-01

    Digital video and accompanying editing software are increasingly becoming more accessible for researchers in terms of ease of use and cost. The rich, visually appealing and seductive nature of video-based data can convey a strong sense of direct experience with the phenomena studied (Pea, 1999). However, the ease of selection and editing of…

  2. Human Rights Education and the Research Process: Action Research as a Tool for Reflection and Change

    Science.gov (United States)

    Tavares, Celma

    2016-01-01

    Human rights education (HRE) aims to achieve a change of mindsets and social attitudes that entails the construction of a culture of respect towards those values it teaches. Although HRE is a recent field of study, its consolidation in Latin America is a fact. During the latest decades several authors have carried out research related to HRE that…

  3. DMPwerkzeug - A tool to support the planning, implementation, and organization of research data management.

    Science.gov (United States)

    Klar, Jochen; Engelhardt, Claudia; Neuroth, Heike; Enke, Harry

    2016-04-01

    Following the call to make the results of publicly funded research openly accessible, more and more funding agencies demand the submission of a data management plan (DMP) as part of the application process. These documents specify, how the data management of the project is organized and what datasets will be published when. Of particular importance for European researchers is the Open Data Research Pilot of Horizon 2020 which requires data management plans for a set of 9 selected research fields from social sciences to nanotechnology. In order to assist the researchers creating these documents, several institutions developed dedicated software tools. The most well-known are DMPonline by the Digital Curation Centre (DCC) and DMPtool by the California Digital Library (CDL) - both extensive and well received web applications. The core functionality of these tools is the assisted editing of the DMP templates provided by the particular funding agency.While this is certainly helpful, especially in an environment with a plethora of different funding agencies like the UK or the USA, these tools are somewhat limited to this particular task and don't utilise the full potential of DMP. Beyond the purpose of fulfilling funder requirements, DMP can be useful for a number of additional tasks. In the initial conception phase of a project, they can be used as a planning tool to determine which date management activities and measures are necessary throughout the research process, to assess which resources are needed, and which institutions (computing centers, libraries, data centers) should be involved. During the project, they can act as a constant reference or guideline for the handling of research data. They also determine where the data will be stored after the project has ended and whether it can be accessed by the public, helping to take into account resulting requirements of the data center or actions necessary to ensure re-usability by others from early on. Ideally, a DMP

  4. Towards a Reflection Repertoire: Using a Thinking Tool to Understand Tensions in an Action Research Project

    Science.gov (United States)

    Aas, Marit

    2014-01-01

    Most action researchers agree that action research consists of cycles of planning, acting, reflecting, and taking further action. However, in action research literature, there is something missing. The nature of reflection in the action research process, including its relationship with the tensions that arise while discussing purposes, processes,…

  5. [Research utilization by health managers: validating a self-assessment tool].

    Science.gov (United States)

    González-Block, Miguel Angel; Mercado, Francisco Javier; Ochoa, Héctor; Rivera, Héctor; Idrovo, Alvaro J

    2008-01-01

    A tool was adapted and evaluated for the self-assessment by health management teams of their capacity to utilize research, distinguishing between its acquisition, analysis, adaptation and application. The tool was translated into Spanish and a manual was created. The manual was submitted for authorization to the Ethics Committee of the National Public Health Institute of Mexico. The kit was sent to 122 units (response rate of 84.4%), covering a wide range of institutions in six contrasting states of Mexico according to the Human Development Index (HDI). The tool was validated internally and externally using statistical methods. Differences were observed in the teams' research utilization capacity within each phase, regardless of their composition by gender, experience or academic level but with differences according to the extent of involvement in patient care and to the states' HDI. The tool was validated both internally and externally for its application under widely varying conditions in Mexico. The tool can be applied in any Spanish speaking country.

  6. Characterizing urban traffic exposures using transportation planning tools: an illustrated methodology for health researchers.

    Science.gov (United States)

    Rioux, Christine L; Gute, David M; Brugge, Doug; Peterson, Scott; Parmenter, Barbara

    2010-03-01

    Exposure to elevated levels of vehicular traffic has been associated with adverse cardiovascular and respiratory health effects in a range of populations, including children, the elderly, and individuals with pre-existing heart conditions, diabetes, obesity, and genetic susceptibilities. As these relationships become clearer, public health officials will need to have access to methods to identify areas of concern in terms of elevated traffic levels and susceptible populations. This paper briefly reviews current approaches for characterizing traffic exposure and then presents a detailed method that can be employed by public health officials and other researchers in performing screening assessments to define areas of potential concern within a particular locale and, with appropriate caveats, in epidemiologic studies examining traffic-related health impacts at the intra-urban scale. The method is based on two exposure parameters extensively used in numerous epidemiologic studies of traffic and health-proximity to high traffic roadways and overall traffic density. The method is demonstrated with publically available information on susceptible populations, traffic volumes, and Traffic Analysis Zones, a transportation planning tool long used by Metropolitan Planning Agencies and planners across the USA but presented here as a new application which can be used to spatially assess possible traffic-related impacts on susceptible populations. Recommendations are provided for the appropriate use of this methodology, along with its limitations.

  7. GERLUMPH DATA RELEASE 1: HIGH-RESOLUTION COSMOLOGICAL MICROLENSING MAGNIFICATION MAPS AND eResearch TOOLS

    Energy Technology Data Exchange (ETDEWEB)

    Vernardos, G.; Fluke, C. J.; Croton, D. [Centre for Astrophysics and Supercomputing, Swinburne University of Technology, P.O. Box 218, Hawthorn, Victoria, 3122 (Australia); Bate, N. F. [Sydney Institute for Astronomy, School of Physics, A28, University of Sydney, NSW, 2006 (Australia)

    2014-03-01

    As synoptic all-sky surveys begin to discover new multiply lensed quasars, the flow of data will enable statistical cosmological microlensing studies of sufficient size to constrain quasar accretion disk and supermassive black hole properties. In preparation for this new era, we are undertaking the GPU-Enabled, High Resolution cosmological MicroLensing parameter survey (GERLUMPH). We present here the GERLUMPH Data Release 1, which consists of 12,342 high resolution cosmological microlensing magnification maps and provides the first uniform coverage of the convergence, shear, and smooth matter fraction parameter space. We use these maps to perform a comprehensive numerical investigation of the mass-sheet degeneracy, finding excellent agreement with its predictions. We study the effect of smooth matter on microlensing induced magnification fluctuations. In particular, in the minima and saddle-point regions, fluctuations are enhanced only along the critical line, while in the maxima region they are always enhanced for high smooth matter fractions (≈0.9). We describe our approach to data management, including the use of an SQL database with a Web interface for data access and online analysis, obviating the need for individuals to download large volumes of data. In combination with existing observational databases and online applications, the GERLUMPH archive represents a fundamental component of a new microlensing eResearch cloud. Our maps and tools are publicly available at http://gerlumph.swin.edu.au/.

  8. CUAHSI Data Services: Tools and Cyberinfrastructure for Water Data Discovery, Research and Collaboration

    Science.gov (United States)

    Seul, M.; Brazil, L.; Castronova, A. M.

    2017-12-01

    CUAHSI Data Services: Tools and Cyberinfrastructure for Water Data Discovery, Research and CollaborationEnabling research surrounding interdisciplinary topics often requires a combination of finding, managing, and analyzing large data sets and models from multiple sources. This challenge has led the National Science Foundation to make strategic investments in developing community data tools and cyberinfrastructure that focus on water data, as it is central need for many of these research topics. CUAHSI (The Consortium of Universities for the Advancement of Hydrologic Science, Inc.) is a non-profit organization funded by the National Science Foundation to aid students, researchers, and educators in using and managing data and models to support research and education in the water sciences. This presentation will focus on open-source CUAHSI-supported tools that enable enhanced data discovery online using advanced searching capabilities and computational analysis run in virtual environments pre-designed for educators and scientists so they can focus their efforts on data analysis rather than IT set-up.

  9. Compartmentalized Microfluidic Platforms: The Unrivaled Breakthrough of In Vitro Tools for Neurobiological Research.

    Science.gov (United States)

    Neto, Estrela; Leitão, Luís; Sousa, Daniela M; Alves, Cecília J; Alencastre, Inês S; Aguiar, Paulo; Lamghari, Meriem

    2016-11-16

    Microfluidic technology has become a valuable tool to the scientific community, allowing researchers to study fine cellular mechanisms with higher variable control compared with conventional systems. It has evolved tremendously, and its applicability and flexibility made its usage grow exponentially and transversely to several research fields. This has been particularly noticeable in neuroscience research, where microfluidic platforms made it possible to address specific questions extending from axonal guidance, synapse formation, or axonal transport to the development of 3D models of the CNS to allow pharmacological testing and drug screening. Furthermore, the continuous upgrade of microfluidic platforms has allowed a deeper study of the communication occurring between different neuronal and glial cells or between neurons and other peripheral tissues, both in physiological and pathological conditions. Importantly, the evolution of microfluidic technology has always been accompanied by the development of new computational tools addressing data acquisition, analysis, and modeling. Copyright © 2016 the authors 0270-6474/16/3611573-12$15.00/0.

  10. A Low Cost, Modular Robotics Tool Carrier For Precision Agriculture Research

    DEFF Research Database (Denmark)

    Nielsen, S H; Jensen, K; Bøgild, A

    18x80 cm footprint track modules each with an integrated 3.5 kW electric motor, gear and motor controller. The track modules are mounted on the side of an exchangeable tool platform which allows an adjustable width and clearing height of the robot. The 48 V lithium power pack lasts 10 hours......Current research within agricultural crop production focus on using autonomous robot technology to optimize the production efficiency, enhance sustainability and minimize tedious, monotonous and wearing tasks. But progress is slow partly because of the lack of flexible and low cost robotic...... platforms suitable for research within precision agriculture. This paper presents Armadillo, a $50k field robotic tool carrier with a modular design which makes the robot configurable and adaptable to a wide range of precision agriculture research projects. Armadillo weighs around 425 kg and consists of two...

  11. Balancing the role of the dental school in teaching, research and patient care; including care for underserved areas.

    Science.gov (United States)

    Holbrook, W P; Brodin, P; Balciuniene, I; Brukiene, V; Bucur, M V; Corbet, E; Dillenberg, J; Djukanovic, D; Ekanayake, K; Eriksen, H; Fisher, J; Goffin, G; Hull, P; Kumchai, T; Lumley, P; Lund, J; Mathur, V; Novaes, A; Puriene, A; Roger-Leroi, V; Saito, I; Turner, S; Mabelya, L

    2008-02-01

    Inequalities within dentistry are common and are reflected in wide differences in the levels of oral health and the standard of care available both within and between countries and communities. Furthermore there are patients, particularly those with special treatment needs, who do not have the same access to dental services as the general public. The dental school should aim to recruit students from varied backgrounds into all areas covered by the oral healthcare team and to train students to treat the full spectrum of patients including those with special needs. It is essential, however, that the dental student achieves a high standard of clinical competence and this cannot be gained by treating only those patients with low expectations for care. Balancing these aspects of clinical education is difficult. Research is an important stimulus to better teaching and better clinical care. It is recognized that dental school staff should be active in research, teaching, clinical work and frequently administration. Maintaining a balance between the commitments to clinical care, teaching and research while also taking account of underserved areas in each of these categories is a difficult challenge but one that has to be met to a high degree in a successful, modern dental school.

  12. PET in tumor imaging: research only or a cost effective clinical tool?

    International Nuclear Information System (INIS)

    Wahl, R.L.

    1997-01-01

    PET imaging has for many years been a versatile tool for non-invasive imaging of neuro-physiology and, indeed, whole body physiology. Quantitative PET imaging of trace amounts of radioactivity is scientifically elegant and can be very complex. This lecture focuses on whether and where this test is clinically useful. Because of the research tradition, PET imaging has been perceived as an 'expensive' test, as it costs more per scan than CT and MRI scans at most institutions. Such a superficial analysis is incorrect, however, as it is increasingly recognized that imaging costs, which in some circumstances will be increased by the use of PET, are only a relatively small component of patient care costs. Thus, PET may raise imaging costs and the number of imaging procedures in some settings, though PET may reduce imaging test numbers in other settings. However, the analysis must focus on the total costs of patient management. Analyses focused on total patient care costs, including cost of hospitalization and cost surgery as well as imaging costs, have shown that PET can substantially reduce total patient care costs in several settings. This is achieved by providing a more accurate diagnosis, and thus having fewer instances of an incorrect diagnosis resulting in subsequent inappropriate surgery or investigations. Several institutions have shown scenarios in which PET for tumor imaging is cost effective. While the specific results of the analyses vary based on disease prevalence and cost input values for each procedure, as well as the projected performance of PET, the similar results showing total care cost savings in the management of several common cancers, strongly supports the rational for the use of PET in cancer management. In addition, promising clinical results are forthcoming in several other illnesses, suggesting PET will have broader utility than these uses, alone. Thus, while PET is an 'expensive' imaging procedure and has considerable utility as a research

  13. Tools for adequacy of research lines of research institutes: the example of IPEN

    International Nuclear Information System (INIS)

    Sacramento, Jose Miguel Noronha

    2011-01-01

    This work aims to assist research institutes, notably the IPEN, in order to improve their assertiveness in the process of defining their research lines. New evolutionary speeds have increased exponentially requiring greater synchronism and multiple and coordinated action from the three fundamental elements in order to assure the development of the contemporary society: Government, Productive Structure and Infrastructure in Science and Technology. This environment increasingly dynamic and mutant imposes greater proximity with the socioeconomic environment when former client-consumer has become the co-creator of knowledge and supplier of energy now contained in a new standard of social relations, called Networked Society. The difference in time for the University, the Productive Structure and Government is function of its main activities: Science, Market and the achievement of Public Opinion, respectively. The equation that will harmonize and find synergies between these three dimensions is the contemporary challenge for those who seek to innovate and advance knowledge in order to improve the standard of living of the society. In this work is shown that research institutes must believe in the words of Robert Plomin and start connecting to the several links in different chains in order to make use of a collective intelligence that continuously expands in speed and quality higher than in any other time in human history. The comparison among the results obtained from the different methodologies of analysis proposed in this work allows finding out strengths and weaknesses, threats and opportunities of the IPEN providing subsidies in order to find better ways to tailor its performance to the new demands. (author)

  14. New Tools for New Research in Psychiatry: A Scalable and Customizable Platform to Empower Data Driven Smartphone Research.

    Science.gov (United States)

    Torous, John; Kiang, Mathew V; Lorme, Jeanette; Onnela, Jukka-Pekka

    2016-05-05

    A longstanding barrier to progress in psychiatry, both in clinical settings and research trials, has been the persistent difficulty of accurately and reliably quantifying disease phenotypes. Mobile phone technology combined with data science has the potential to offer medicine a wealth of additional information on disease phenotypes, but the large majority of existing smartphone apps are not intended for use as biomedical research platforms and, as such, do not generate research-quality data. Our aim is not the creation of yet another app per se but rather the establishment of a platform to collect research-quality smartphone raw sensor and usage pattern data. Our ultimate goal is to develop statistical, mathematical, and computational methodology to enable us and others to extract biomedical and clinical insights from smartphone data. We report on the development and early testing of Beiwe, a research platform featuring a study portal, smartphone app, database, and data modeling and analysis tools designed and developed specifically for transparent, customizable, and reproducible biomedical research use, in particular for the study of psychiatric and neurological disorders. We also outline a proposed study using the platform for patients with schizophrenia. We demonstrate the passive data capabilities of the Beiwe platform and early results of its analytical capabilities. Smartphone sensors and phone usage patterns, when coupled with appropriate statistical learning tools, are able to capture various social and behavioral manifestations of illnesses, in naturalistic settings, as lived and experienced by patients. The ubiquity of smartphones makes this type of moment-by-moment quantification of disease phenotypes highly scalable and, when integrated within a transparent research platform, presents tremendous opportunities for research, discovery, and patient health.

  15. Qualitative study to develop processes and tools for the assessment and tracking of African institutions' capacity for operational health research.

    Science.gov (United States)

    Wallis, Selina; Cole, Donald C; Gaye, Oumar; Mmbaga, Blandina T; Mwapasa, Victor; Tagbor, Harry; Bates, Imelda

    2017-09-05

    Research is key to achieving global development goals. Our objectives were to develop and test an evidence-informed process for assessing health research management and support systems (RMSS) in four African universities and for tracking interventions to address capacity gaps. Four African universities. 83 university staff and students from 11 cadres. A literature-informed 'benchmark' was developed and used to itemise all components of a university's health RMSS. Data on all components were collected during site visits to four African universities using interview guides, document reviews and facilities observation guides. Gaps in RMSS capacity were identified against the benchmark and institutional action plans developed to remedy gaps. Progress against indicators was tracked over 15 months and common challenges and successes identified. Common gaps in operational health research capacity included no accessible research strategy, a lack of research e-tracking capability and inadequate quality checks for proposal submissions and contracts. Feedback indicated that the capacity assessment was comprehensive and generated practical actions, several of which were no-cost. Regular follow-up helped to maintain focus on activities to strengthen health research capacity in the face of challenges. Identification of each institutions' strengths and weaknesses against an evidence-informed benchmark enabled them to identify gaps in in their operational health research systems, to develop prioritised action plans, to justify resource requests to fulfil the plans and to track progress in strengthening RMSS. Use of a standard benchmark, approach and tools enabled comparisons across institutions which has accelerated production of evidence about the science of research capacity strengthening. The tools could be used by institutions seeking to understand their strengths and to address gaps in research capacity. Research capacity gaps that were common to several institutions could be

  16. The Article Idea Chart: A participatory action research tool to aid involvement in dissemination

    Directory of Open Access Journals (Sweden)

    Cheryl Forchuk

    2014-06-01

    Full Text Available Participatory-action research encourages the involvement of all key stakeholders in the research process and is especially well suited to mental health research. Previous literature outlines the importance of engaging stakeholders in the development of research questions and methodologies, but little has been written about ensuring the involvement of all stakeholders (especially non-academic members in dissemination opportunities such as publication development. The Article Idea Chart was developed as a specific methodology for engaging all stakeholders in data analysis and publication development. It has been successfully utilised in a number of studies and is an effective tool for ensuring the dissemination process of participatory-action research results is both inclusive and transparent to all team members, regardless of stakeholder group. Keywords: participatory-action research, mental health, dissemination, community capacity building, publications, authorship

  17. Fotonovela as a Research Tool in Image-Based Participatory Research with Immigrant Children

    Directory of Open Access Journals (Sweden)

    Anna Kirova PhD

    2008-06-01

    Full Text Available In this article the authors explore the effect of word-image relationships on the collection of data and the reporting of research results for a study involving the development of a series of fotonovelas with immigrant children in an inner-city school. The central question explored in this article is Can experiences such as producing visual narratives in the form of fotonovelas stimulate multiple expressions of voice and position and bring awareness of embodied ways of communicating in a culture-rich school context? The processes involved in collaboratively developing the photographic narrative format of the fotonovela combine visual elements and structures and embodied, reflective performance together with written text. As a research method fotonovela does not merely translate verbal into visual representations but constructs a hybrid photo-image-text that opens new spaces for dialogue, resistance, and representation of a new way of knowing that changes the way of seeing and has the potential to change the author's and the reader's self-understanding.

  18. Development of a community sustainability visualization tool through integration of US EPA’s Sustainable and Health Community Research Program tasks

    Science.gov (United States)

    We propose a 2-day session combining multiple components of an ongoing integrative research program in USEPA’s Office of Research and Development into a functional community sustainability visualization and assessment tool. The working group will include project leads for a US H...

  19. Establishing a community-wide DNA barcode library as a new tool for arctic research

    DEFF Research Database (Denmark)

    Wirta, Helena; Várkonyi, Gergely; Rasmussen, Claus

    2016-01-01

    DNA sequences offer powerful tools for describing the members and interactions of natural communities. In this study, we establish the to-date most comprehensive library of DNA barcodes for a terrestrial site, including all known macroscopic animals and vascular plants of an intensively studied a...

  20. Thermal Error Test and Intelligent Modeling Research on the Spindle of High Speed CNC Machine Tools

    Science.gov (United States)

    Luo, Zhonghui; Peng, Bin; Xiao, Qijun; Bai, Lu

    2018-03-01

    Thermal error is the main factor affecting the accuracy of precision machining. Through experiments, this paper studies the thermal error test and intelligent modeling for the spindle of vertical high speed CNC machine tools in respect of current research focuses on thermal error of machine tool. Several testing devices for thermal error are designed, of which 7 temperature sensors are used to measure the temperature of machine tool spindle system and 2 displacement sensors are used to detect the thermal error displacement. A thermal error compensation model, which has a good ability in inversion prediction, is established by applying the principal component analysis technology, optimizing the temperature measuring points, extracting the characteristic values closely associated with the thermal error displacement, and using the artificial neural network technology.

  1. CONFERENCE SUMMARY: Summary and comment on superconducting analogue electronics research, including materials and fabrication, as presented at ISEC 07

    Science.gov (United States)

    Foley, C. P.

    2007-11-01

    The main theme at ISEC 2007 for superconducting materials, fabrication and analogue electronics was the description of incremental developments, including a few new directions that indicate breakthroughs in this area of research. The work on applications focused on their cost-benefit analysis (in order to improve their appeal), the development of simpler systems, making more of the data collected, improving packaging and being responsive to the power handling requirements for commercial systems. All papers presenting this level of research highlighted the importance of obtaining all the necessary details in order to investigate analogue devices and the effectiveness and commercial viability of their systems. This stage of development is important if we are to achieve the transition of superconducting electronics from the laboratory to commercial use. There were some exciting disruptive breakthroughs reported. These were in the areas of nano-SQUIDs, rotating gradiometers, superconducting scanning tunnelling microscopy (Hayashi et al) and the potential of superconducting photonics using optical interfaces with superconducting vortex flow transistors, for example. The materials research in low (LTS), high (HTS) and medium (MTS) critical temperature superconductors was reported. In LTS, nitrides emerged as important materials for use as new tunnel barriers, either insulating or semiconducting. Papers on BaN, NbN, TaN, GaN and Nb-Si superconducting materials were also presented. The MTS material of MgB2 is still under development (Zhao et al). There were also new research groups from South Africa and Turkey attending the conference. The fabrication research presented covered the areas of critical current Ic spread, which is still an issue in reducing the reproducibility of Josephson junctions, a 150 mm process for Nb/Al-AlOx/Nb and methods to improve barrier layers using both new materials and smooth surfaces at thin film interfaces (Du et al). New methods to make sub

  2. A Web-Based Tool for Automatic Data Collection, Curation, and Visualization of Complex Healthcare Survey Studies including Social Network Analysis

    Directory of Open Access Journals (Sweden)

    José Alberto Benítez

    2017-01-01

    Full Text Available There is a great concern nowadays regarding alcohol consumption and drug abuse, especially in young people. Analyzing the social environment where these adolescents are immersed, as well as a series of measures determining the alcohol abuse risk or personal situation and perception using a number of questionnaires like AUDIT, FAS, KIDSCREEN, and others, it is possible to gain insight into the current situation of a given individual regarding his/her consumption behavior. But this analysis, in order to be achieved, requires the use of tools that can ease the process of questionnaire creation, data gathering, curation and representation, and later analysis and visualization to the user. This research presents the design and construction of a web-based platform able to facilitate each of the mentioned processes by integrating the different phases into an intuitive system with a graphical user interface that hides the complexity underlying each of the questionnaires and techniques used and presenting the results in a flexible and visual way, avoiding any manual handling of data during the process. Advantages of this approach are shown and compared to the previous situation where some of the tasks were accomplished by time consuming and error prone manipulations of data.

  3. Automated Tools for Clinical Research Data Quality Control using NCI Common Data Elements.

    Science.gov (United States)

    Hudson, Cody L; Topaloglu, Umit; Bian, Jiang; Hogan, William; Kieber-Emmons, Thomas

    2014-01-01

    Clinical research data generated by a federation of collection mechanisms and systems often produces highly dissimilar data with varying quality. Poor data quality can result in the inefficient use of research data or can even require the repetition of the performed studies, a costly process. This work presents two tools for improving data quality of clinical research data relying on the National Cancer Institute's Common Data Elements as a standard representation of possible questions and data elements to A: automatically suggest CDE annotations for already collected data based on semantic and syntactic analysis utilizing the Unified Medical Language System (UMLS) Terminology Services' Metathesaurus and B: annotate and constrain new clinical research questions though a simple-to-use "CDE Browser." In this work, these tools are built and tested on the open-source LimeSurvey software and research data analyzed and identified to contain various data quality issues captured by the Comprehensive Research Informatics Suite (CRIS) at the University of Arkansas for Medical Sciences.

  4. Social Networking Site Usage Among Childhood Cancer Survivors - A Potential Tool for Research Recruitment?

    Science.gov (United States)

    Seltzer, Erica D.; Stolley, Melinda R.; Mensah, Edward K.; Sharp, Lisa K.

    2014-01-01

    Purpose The recent and rapid growth of social networking site (SNS) use presents a unique public health opportunity to develop effective strategies for the recruitment of hard-to-reach participants for cancer research studies. This survey investigated childhood cancer survivors’ reported use of SNS such as facebook or MySpace and their perceptions of using SNS, for recruitment into survivorship research. Methods Sixty White, Black and Hispanic, adult childhood cancer survivors (range 18 – 48 years of age) that were randomly selected from a larger childhood cancer study, the Chicago Healthy Living Study (CHLS), participated in this pilot survey. Telephone surveys were conducted to understand current SNS activity and attitudes towards using SNS as a cancer research recruitment tool. Results Seventy percent of participants reported SNS usage of which 80% were at least weekly users and 79 % reported positive attitudes towards the use of SNS as a recruitment tool for survivorship research. Conclusions and implications for cancer survivors The results of this pilot study revealed that SNS use was high and regular among the childhood cancer survivors sampled. Most had positive attitudes towards using SNS for recruitment of research. The results of this pilot survey suggest that SNS may offer an alternative approach for recruitment of childhood cancer survivors into research. PMID:24532046

  5. Social networks, web-based tools and diseases: implications for biomedical research.

    Science.gov (United States)

    Costa, Fabricio F

    2013-03-01

    Advances in information technology have improved our ability to gather, collect and analyze information from individuals online. Social networks can be seen as a nonlinear superposition of a multitude of complex connections between people where the nodes represent individuals and the links between them capture a variety of different social interactions. The emergence of different types of social networks has fostered connections between individuals, thus facilitating data exchange in a variety of fields. Therefore, the question posed now is "can these same tools be applied to life sciences in order to improve scientific and medical research?" In this article, I will review how social networks and other web-based tools are changing the way we approach and track diseases in biomedical research. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. CRISPR: a Versatile Tool for Both Forward and Reverse Genetics Research

    Science.gov (United States)

    Gurumurthy, Channabasavaiah B.; Grati, M'hamed; Ohtsuka, Masato; Schilit, Samantha L.P.; Quadros, Rolen M.; Liu, Xue Zhong

    2016-01-01

    Human genetics research employs the two opposing approaches of forward and reverse genetics. While forward genetics identifies and links a mutation to an observed disease etiology, reverse genetics induces mutations in model organisms to study their role in disease. In most cases, causality for mutations identified by forward genetics is confirmed by reverse genetics through the development of genetically engineered animal models and an assessment of whether the model can recapitulate the disease. While many technological advances have helped improve these approaches, some gaps still remain. CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated) system, which has emerged as a revolutionary genetic engineering tool, holds great promise for closing such gaps. By combining the benefits of forward and reverse genetics, it has dramatically expedited human genetics research. We provide a perspective on the power of CRISPR-based forward and reverse genetics tools in human genetics and discuss its applications using some disease examples. PMID:27384229

  7. A low cost, modular robotics tool carrier for precision agriculture research

    DEFF Research Database (Denmark)

    Jensen, Kjeld; Nielsen, Søren Hundevadt; Bøgild, Anders

    platforms suitable for research within precision agriculture. This paper presents Armadillo, a $50k field robotic tool carrier with a modular design which makes the robot configurable and adaptable to a wide range of precision agriculture research projects. Armadillo weighs around 425 kg and consists of two...... 18x80 cm footprint track modules each with an integrated 3.5 kW electric motor, gear and motor controller. The track modules are mounted on the side of an exchangeable tool platform which allows an adjustable width and clearing height of the robot. The 48 V lithium power pack lasts 10 hours...... of operation. Armadillos industrial grade Linux based FroboBox computer runs the FroboMind architecture which is based on the Robot Operating System (ROS) by Willow Garage. FroboMind is a novel generic architecture that has been implemented and successfully tested on different field robots. It has been...

  8. Increasing resource allocation and research into tobacco control activities: a comprehensive approach including primary prevention, treatment and brief intervention.

    Science.gov (United States)

    Richmond, R

    1993-01-01

    The range of tobacco control activities should be viewed as essential parts of a complex multi-component puzzle. Intervention strategies designed to address tobacco control should be comprehensive and include both primary and secondary prevention activities and be multi-faceted and capable of bringing about change at both the individual and broader social and cultural levels. In this paper I argue for a mutually inclusive framework in which the various components contribute in important and different ways. I examine the prevalence of smoking and identify the high risk groups, then I examine the range of available strategies and present the evidence for their success. I discuss the primary prevention approaches such as warning labels, taxes, price increases, workplace bans, education in schools, mass media and self-help materials, as well as brief interventions and treatment strategies which are conducted at the worksite, general practice and specialized cessation clinics. The areas for future research are delineated for increased resource allocation and include: the best ways to disseminate brief interventions to smokers, methods to motivate smokers; training of health professionals to deliver brief interventions; enhancing quitting and access to existing treatment resources among specific disadvantaged minority groups, e.g. migrants, unemployed youth, the effect on smoking prevalence of warning labels on cigarette packets and price rises on cigarettes.

  9. A compilation of Web-based research tools for miRNA analysis.

    Science.gov (United States)

    Shukla, Vaibhav; Varghese, Vinay Koshy; Kabekkodu, Shama Prasada; Mallya, Sandeep; Satyamoorthy, Kapaettu

    2017-09-01

    Since the discovery of microRNAs (miRNAs), a class of noncoding RNAs that regulate the gene expression posttranscriptionally in sequence-specific manner, there has been a release of number of tools useful for both basic and advanced applications. This is because of the significance of miRNAs in many pathophysiological conditions including cancer. Numerous bioinformatics tools that have been developed for miRNA analysis have their utility for detection, expression, function, target prediction and many other related features. This review provides a comprehensive assessment of web-based tools for the miRNA analysis that does not require prior knowledge of any computing languages. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  10. German translation of the Alberta Context Tool and two measures of research use: methods, challenges and lessons learned.

    Science.gov (United States)

    Hoben, Matthias; Mahler, Cornelia; Bär, Marion; Berger, Sarah; Squires, Janet E; Estabrooks, Carole A; Behrens, Johann

    2013-11-16

    Understanding the relationship between organizational context and research utilization is key to reducing the research-practice gap in health care. This is particularly true in the residential long term care (LTC) setting where relatively little work has examined the influence of context on research implementation. Reliable, valid measures and tools are a prerequisite for studying organizational context and research utilization. Few such tools exist in German. We thus translated three such tools (the Alberta Context Tool and two measures of research use) into German for use in German residential LTC. We point out challenges and strategies for their solution unique to German residential LTC, and demonstrate how resolving specific challenges in the translation of the health care aide instrument version streamlined the translation process of versions for registered nurses, allied health providers, practice specialists, and managers. Our translation methods were based on best practices and included two independent forward translations, reconciliation of the forward translations, expert panel discussions, two independent back translations, reconciliation of the back translations, back translation review, and cognitive debriefing. We categorized the challenges in this translation process into seven categories: (1) differing professional education of Canadian and German care providers, (2) risk that German translations would become grammatically complex, (3) wordings at risk of being misunderstood, (4) phrases/idioms non-existent in German, (5) lack of corresponding German words, (6) limited comprehensibility of corresponding German words, and (7) target persons' unfamiliarity with activities detailed in survey items. Examples of each challenge are described with strategies that we used to manage the challenge. Translating an existing instrument is complex and time-consuming, but a rigorous approach is necessary to obtain instrument equivalence. Essential components were

  11. German translation of the Alberta context tool and two measures of research use: methods, challenges and lessons learned

    Science.gov (United States)

    2013-01-01

    Background Understanding the relationship between organizational context and research utilization is key to reducing the research-practice gap in health care. This is particularly true in the residential long term care (LTC) setting where relatively little work has examined the influence of context on research implementation. Reliable, valid measures and tools are a prerequisite for studying organizational context and research utilization. Few such tools exist in German. We thus translated three such tools (the Alberta Context Tool and two measures of research use) into German for use in German residential LTC. We point out challenges and strategies for their solution unique to German residential LTC, and demonstrate how resolving specific challenges in the translation of the health care aide instrument version streamlined the translation process of versions for registered nurses, allied health providers, practice specialists, and managers. Methods Our translation methods were based on best practices and included two independent forward translations, reconciliation of the forward translations, expert panel discussions, two independent back translations, reconciliation of the back translations, back translation review, and cognitive debriefing. Results We categorized the challenges in this translation process into seven categories: (1) differing professional education of Canadian and German care providers, (2) risk that German translations would become grammatically complex, (3) wordings at risk of being misunderstood, (4) phrases/idioms non-existent in German, (5) lack of corresponding German words, (6) limited comprehensibility of corresponding German words, and (7) target persons’ unfamiliarity with activities detailed in survey items. Examples of each challenge are described with strategies that we used to manage the challenge. Conclusion Translating an existing instrument is complex and time-consuming, but a rigorous approach is necessary to obtain instrument

  12. DataUp: A tool to help researchers describe and share tabular data.

    Science.gov (United States)

    Strasser, Carly; Kunze, John; Abrams, Stephen; Cruse, Patricia

    2014-01-01

    Scientific datasets have immeasurable value, but they lose their value over time without proper documentation, long-term storage, and easy discovery and access. Across disciplines as diverse as astronomy, demography, archeology, and ecology, large numbers of small heterogeneous datasets (i.e., the long tail of data) are especially at risk unless they are properly documented, saved, and shared. One unifying factor for many of these at-risk datasets is that they reside in spreadsheets. In response to this need, the California Digital Library (CDL) partnered with Microsoft Research Connections and the Gordon and Betty Moore Foundation to create the DataUp data management tool for Microsoft Excel. Many researchers creating these small, heterogeneous datasets use Excel at some point in their data collection and analysis workflow, so we were interested in developing a data management tool that fits easily into those work flows and minimizes the learning curve for researchers. The DataUp project began in August 2011. We first formally assessed the needs of researchers by conducting surveys and interviews of our target research groups: earth, environmental, and ecological scientists. We found that, on average, researchers had very poor data management practices, were not aware of data centers or metadata standards, and did not understand the benefits of data management or sharing. Based on our survey results, we composed a list of desirable components and requirements and solicited feedback from the community to prioritize potential features of the DataUp tool. These requirements were then relayed to the software developers, and DataUp was successfully launched in October 2012.

  13. Report of the 2. research co-ordination meeting of the co-ordinated research programme on the development of computer-based troubleshooting tools and instruments

    International Nuclear Information System (INIS)

    1998-11-01

    The Research coordination meeting reviewed current results on the Development of Computer-Based Troubleshooting Tools and Instruments. Presentations at the meeting were made by the participants, and the project summary reports include: PC based software for troubleshooting microprocessor-based instruments; technical data base software; design and construction of a random pulser for maintenance and quality control of a nuclear counting system; microprocessor-based power conditioner; in-circuit emulator for microprocessor-based nuclear instruments; PC-based analog signal generator for simulated detector signals and arbitrary test waveforms for testing of nuclear instruments; expert system for nuclear instrument troubleshooting; development and application of versatile computer-based measurement and diagnostic tools; and development of a programmable signal generator for troubleshooting of nuclear instrumentation

  14. Cost-effective evolution of research prototypes into end-user tools: The MACH case study

    DEFF Research Database (Denmark)

    Störrle, Harald

    2017-01-01

    Much of Software Engineering research needs to provide an implementation as proof-of-concept. Often such implementations are created as exploratory prototypes without polished user interfaces, making it difficult to (1) run user studies to validate the tool's contribution, (2) validate the author...... command line interpreter rather than (costly) graphical user interface, we achieved the core goal of quickly deploying research results to a broader audience while keeping the required effort to an absolute minimum. We analyze MACH as a case study of how requirements and constraints in an academic...

  15. Tools for Citizen-Science Recruitment and Student Engagement in Your Research and in Your Classroom.

    Science.gov (United States)

    Council, Sarah E; Horvath, Julie E

    2016-03-01

    The field of citizen science is exploding and offers not only a great way to engage the general public in science literacy through primary research, but also an avenue for teaching professionals to engage their students in meaningful community research experiences. Though this field is expanding, there are many hurdles for researchers and participants, as well as challenges for teaching professionals who want to engage their students. Here we highlight one of our projects that engaged many citizens in Raleigh, NC, and across the world, and we use this as a case study to highlight ways to engage citizens in all kinds of research. Through the use of numerous tools to engage the public, we gathered citizen scientists to study skin microbes and their associated odors, and we offer valuable ideas for teachers to tap into resources for their own students and potential citizen-science projects.

  16. Tools for Citizen-Science Recruitment and Student Engagement in Your Research and in Your Classroom

    Directory of Open Access Journals (Sweden)

    Sarah E. Council

    2016-01-01

    Full Text Available The field of citizen science is exploding and offers not only a great way to engage the general public in science literacy through primary research, but also an avenue for teaching professionals to engage their students in meaningful community research experiences. Though this field is expanding, there are many hurdles for researchers and participants, as well as challenges for teaching professionals who want to engage their students. Here we highlight one of our projects that engaged many citizens in Raleigh, NC, and across the world, and we use this as a case study to highlight ways to engage citizens in all kinds of research. Through the use of numerous tools to engage the public, we gathered citizen scientists to study skin microbes and their associated odors, and we offer valuable ideas for teachers to tap into resources for their own students and potential citizen-science projects.

  17. Ethnobotany as a pharmacological research tool and recent developments in CNS-active natural products from ethnobotanical sources.

    Science.gov (United States)

    McClatchey, Will C; Mahady, Gail B; Bennett, Bradley C; Shiels, Laura; Savo, Valentina

    2009-08-01

    The science of ethnobotany is reviewed in light of its multi-disciplinary contributions to natural product research for the development of pharmaceuticals and pharmacological tools. Some of the issues reviewed involve ethical and cultural perspectives of healthcare and medicinal plants. While these are not usually part of the discussion of pharmacology, cultural concerns potentially provide both challenges and insight for field and laboratory researchers. Plant evolutionary issues are also considered as they relate to development of plant chemistry and accessing this through ethnobotanical methods. The discussion includes presentation of a range of CNS-active medicinal plants that have been recently examined in the field, laboratory and/or clinic. Each of these plants is used to illustrate one or more aspects about the valuable roles of ethnobotany in pharmacological research. We conclude with consideration of mutually beneficial future collaborations between field ethnobotanists and pharmacologists.

  18. Qualitative evaluation of the implementation of the Interdisciplinary Management Tool: a reflective tool to enhance interdisciplinary teamwork using Structured, Facilitated Action Research for Implementation.

    Science.gov (United States)

    Nancarrow, Susan A; Smith, Tony; Ariss, Steven; Enderby, Pamela M

    2015-07-01

    Reflective practice is used increasingly to enhance team functioning and service effectiveness; however, there is little evidence of its use in interdisciplinary teams. This paper presents the qualitative evaluation of the Interdisciplinary Management Tool (IMT), an evidence-based change tool designed to enhance interdisciplinary teamwork through structured team reflection. The IMT incorporates three components: an evidence-based resource guide; a reflective implementation framework based on Structured, Facilitated Action Research for Implementation methodology; and formative and summative evaluation components. The IMT was implemented with intermediate care teams supported by independent facilitators in England. Each intervention lasted 6 months and was evaluated over a 12-month period. Data sources include interviews, a focus group with facilitators, questionnaires completed by team members and documentary feedback from structured team reports. Data were analysed qualitatively using the Framework approach. The IMT was implemented with 10 teams, including 253 staff from more than 10 different disciplines. Team challenges included lack of clear vision; communication issues; limited career progression opportunities; inefficient resource use; need for role clarity and service development. The IMT successfully engaged staff in the change process, and resulted in teams developing creative strategies to address the issues identified. Participants valued dedicated time to focus on the processes of team functioning; however, some were uncomfortable with a focus on teamwork at the expense of delivering direct patient care. The IMT is a relatively low-cost, structured, reflective way to enhance team function. It empowers individuals to understand and value their own, and others' roles and responsibilities within the team; identify barriers to effective teamwork, and develop and implement appropriate solutions to these. To be successful, teams need protected time to take

  19. VoiceThread as a Peer Review and Dissemination Tool for Undergraduate Research

    Science.gov (United States)

    Guertin, L. A.

    2012-12-01

    VoiceThread has been utilized in an undergraduate research methods course for peer review and final research project dissemination. VoiceThread (http://www.voicethread.com) can be considered a social media tool, as it is a web-based technology with the capacity to enable interactive dialogue. VoiceThread is an application that allows a user to place a media collection online containing images, audio, videos, documents, and/or presentations in an interface that facilitates asynchronous communication. Participants in a VoiceThread can be passive viewers of the online content or engaged commenters via text, audio, video, with slide annotations via a doodle tool. The VoiceThread, which runs across browsers and operating systems, can be public or private for viewing and commenting and can be embedded into any website. Although few university students are aware of the VoiceThread platform (only 10% of the students surveyed by Ng (2012)), the 2009 K-12 edition of The Horizon Report (Johnson et al., 2009) lists VoiceThread as a tool to watch because of the opportunities it provides as a collaborative learning environment. In Fall 2011, eleven students enrolled in an undergraduate research methods course at Penn State Brandywine each conducted their own small-scale research project. Upon conclusion of the projects, students were required to create a poster summarizing their work for peer review. To facilitate the peer review process outside of class, each student-created PowerPoint file was placed in a VoiceThread with private access to only the class members and instructor. Each student was assigned to peer review five different student posters (i.e., VoiceThread images) with the audio and doodle tools to comment on formatting, clarity of content, etc. After the peer reviews were complete, the students were allowed to edit their PowerPoint poster files for a new VoiceThread. In the new VoiceThread, students were required to video record themselves describing their research

  20. Web-based communication tools in a European research project: the example of the TRACE project

    Directory of Open Access Journals (Sweden)

    Baeten V.

    2009-01-01

    Full Text Available The multi-disciplinary and international nature of large European projects requires powerful managerial and communicative tools to ensure the transmission of information to the end-users. One such project is TRACE entitled “Tracing Food Commodities in Europe”. One of its objectives is to provide a communication system dedicated to be the central source of information on food authenticity and traceability in Europe. This paper explores the web tools used and communication vehicles offered to scientists involved in the TRACE project to communicate internally as well as to the public. Two main tools have been built: an Intranet and a public website. The TRACE website can be accessed at http://www.trace.eu.org. A particular emphasis was placed on the efficiency, the relevance and the accessibility of the information, the publicity of the website as well as the use of the collaborative utilities. The rationale of web space design as well as integration of proprietary software solutions are presented. Perspectives on the using of web tools in the research projects are discussed.

  1. Research on Key Technologies of Unit-Based CNC Machine Tool Assembly Design

    Directory of Open Access Journals (Sweden)

    Zhongqi Sheng

    2014-01-01

    Full Text Available Assembly is the part that produces the maximum workload and consumed time during product design and manufacturing process. CNC machine tool is the key basic equipment in manufacturing industry and research on assembly design technologies of CNC machine tool has theoretical significance and practical value. This study established a simplified ASRG for CNC machine tool. The connection between parts, semantic information of transmission, and geometric constraint information were quantified to assembly connection strength to depict the assembling difficulty level. The transmissibility based on trust relationship was applied on the assembly connection strength. Assembly unit partition based on assembly connection strength was conducted, and interferential assembly units were identified and revised. The assembly sequence planning and optimization of parts in each assembly unit and between assembly units was conducted using genetic algorithm. With certain type of high speed CNC turning center, as an example, this paper explored into the assembly modeling, assembly unit partition, and assembly sequence planning and optimization and realized the optimized assembly sequence of headstock of CNC machine tool.

  2. Community-based participatory research and user-centered design in a diabetes medication information and decision tool.

    Science.gov (United States)

    Henderson, Vida A; Barr, Kathryn L; An, Lawrence C; Guajardo, Claudia; Newhouse, William; Mase, Rebecca; Heisler, Michele

    2013-01-01

    Together, community-based participatory research (CBPR), user-centered design (UCD), and health information technology (HIT) offer promising approaches to improve health disparities in low-resource settings. This article describes the application of CBPR and UCD principles to the development of iDecide/Decido, an interactive, tailored, web-based diabetes medication education and decision support tool delivered by community health workers (CHWs) to African American and Latino participants with diabetes in Southwest and Eastside Detroit. The decision aid is offered in English or Spanish and is delivered on an iPad in participants' homes. The overlapping principles of CBPR and UCD used to develop iDecide/Decido include a user-focused or community approach, equitable academic and community partnership in all study phases, an iterative development process that relies on input from all stakeholders, and a program experience that is specified, adapted, and implemented with the target community. Collaboration between community members, researchers, and developers is especially evident in the program's design concept, animations, pictographs, issue cards, goal setting, tailoring, and additional CHW tools. The principles of CBPR and UCD can be successfully applied in developing health information tools that are easy to use and understand, interactive, and target health disparities.

  3. Science in the Eyes of Preschool Children: Findings from an Innovative Research Tool

    Science.gov (United States)

    Dubosarsky, Mia D.

    How do young children view science? Do these views reflect cultural stereotypes? When do these views develop? These fundamental questions in the field of science education have rarely been studied with the population of preschool children. One main reason is the lack of an appropriate research instrument that addresses preschool children's developmental competencies. Extensive body of research has pointed at the significance of early childhood experiences in developing positive attitudes and interests toward learning in general and the learning of science in particular. Theoretical and empirical research suggests that stereotypical views of science may be replaced by authentic views following inquiry science experience. However, no preschool science intervention program could be designed without a reliable instrument that provides baseline information about preschool children's current views of science. The current study presents preschool children's views of science as gathered from a pioneering research tool. This tool, in the form of a computer "game," does not require reading, writing, or expressive language skills and is operated by the children. The program engages children in several simple tasks involving picture recognition and yes/no answers in order to reveal their views about science. The study was conducted with 120 preschool children in two phases and found that by the age of 4 years, participants possess an emergent concept of science. Gender and school differences were detected. Findings from this interdisciplinary study will contribute to the fields of early childhood, science education, learning technologies, program evaluation, and early childhood curriculum development.

  4. Isolation of a strong Arabidopsis guard cell promoter and its potential as a research tool

    Directory of Open Access Journals (Sweden)

    Siegel Robert S

    2008-02-01

    Full Text Available Abstract Background A common limitation in guard cell signaling research is that it is difficult to obtain consistent high expression of transgenes of interest in Arabidopsis guard cells using known guard cell promoters or the constitutive 35S cauliflower mosaic virus promoter. An additional drawback of the 35S promoter is that ectopically expressing a gene throughout the organism could cause pleiotropic effects. To improve available methods for targeted gene expression in guard cells, we isolated strong guard cell promoter candidates based on new guard cell-specific microarray analyses of 23,000 genes that are made available together with this report. Results A promoter, pGC1(At1g22690, drove strong and relatively specific reporter gene expression in guard cells including GUS (beta-glucuronidase and yellow cameleon YC3.60 (GFP-based calcium FRET reporter. Reporter gene expression was weaker in immature guard cells. The expression of YC3.60 was sufficiently strong to image intracellular Ca2+ dynamics in guard cells of intact plants and resolved spontaneous calcium transients in guard cells. The GC1 promoter also mediated strong reporter expression in clustered stomata in the stomatal development mutant too-many-mouths (tmm. Furthermore, the same promoter::reporter constructs also drove guard cell specific reporter expression in tobacco, illustrating the potential of this promoter as a method for high level expression in guard cells. A serial deletion of the promoter defined a guard cell expression promoter region. In addition, anti-sense repression using pGC1 was powerful for reducing specific GFP gene expression in guard cells while expression in leaf epidermal cells was not repressed, demonstrating strong cell-type preferential gene repression. Conclusion The pGC1 promoter described here drives strong reporter expression in guard cells of Arabidopsis and tobacco plants. It provides a potent research tool for targeted guard cell expression or

  5. Designing and recruiting to UK autism spectrum disorder research databases: do they include representative children with valid ASD diagnoses?

    Science.gov (United States)

    Warnell, F; George, B; McConachie, H; Johnson, M; Hardy, R; Parr, J R

    2015-09-04

    (1) Describe how the Autism Spectrum Database-UK (ASD-UK) was established; (2) investigate the representativeness of the first 1000 children and families who participated, compared to those who chose not to; (3) investigate the reliability of the parent-reported Autism Spectrum Disorder (ASD) diagnoses, and present evidence about the validity of diagnoses, that is, whether children recruited actually have an ASD; (4) present evidence about the representativeness of the ASD-UK children and families, by comparing their characteristics with the first 1000 children and families from the regional Database of children with ASD living in the North East (Dasl(n)e), and children and families identified from epidemiological studies. Recruitment through a network of 50 UK child health teams and self-referral. Parents/carers with a child with ASD, aged 2-16 years, completed questionnaires about ASD and some gave professionals' reports about their children. 1000 families registered with ASD-UK in 30 months. Children of families who participated, and of the 208 who chose not to, were found to be very similar on: gender ratio, year of birth, ASD diagnosis and social deprivation score. The reliability of parent-reported ASD diagnoses of children was very high when compared with clinical reports (over 96%); no database child without ASD was identified. A comparison of gender, ASD diagnosis, age at diagnosis, school placement, learning disability, and deprivation score of children and families from ASD-UK with 1084 children and families from Dasl(n)e, and families from population studies, showed that ASD-UK families are representative of families of children with ASD overall. ASD-UK includes families providing parent-reported data about their child and family, who appear to be broadly representative of UK children with ASD. Families continue to join the databases and more than 3000 families can now be contacted by researchers about UK autism research. Published by the BMJ

  6. Food 21: a research program looking for measures and tools to increase food chain sustainability.

    Science.gov (United States)

    Andersson, Rune; Algers, Bo; Bergström, Lars; Lundström, Kerstin; Nybrant, Thomas; Sjödén, Per-Olow

    2005-06-01

    Food 21, an interdisciplinary research program encompassing the whole agro-food chain, was conducted in Sweden during 1997-2004. The challenges undertaken were to come up with environmental tools and solutions to existing nonsustainable practices along the entire food chain. This required close collaboration between the scientists and the food chain stakeholders. A set of goals characterizing sustainable food production is presented in this paper. Synthesis and systems analysis were the main tools used to analyze the sustainability of proposed changes. In this introduction we give an overview of the Food 21 concept and highlight some results. For example, we found that organic farming and organic products were not in general superior to conventional products and practices with respect to environmental impact and product quality. We also summarize the management experiences in this article, since we consider them to be rather unique and since they contributed to the overall success of the program.

  7. A multimedia consent tool for research participants in the Gambia: a randomized controlled trial.

    Science.gov (United States)

    Afolabi, Muhammed Olanrewaju; McGrath, Nuala; D'Alessandro, Umberto; Kampmann, Beate; Imoukhuede, Egeruan B; Ravinetto, Raffaella M; Alexander, Neal; Larson, Heidi J; Chandramohan, Daniel; Bojang, Kalifa

    2015-05-01

    To assess the effectiveness of a multimedia informed consent tool for adults participating in a clinical trial in the Gambia. Adults eligible for inclusion in a malaria treatment trial (n = 311) were randomized to receive information needed for informed consent using either a multimedia tool (intervention arm) or a standard procedure (control arm). A computerized, audio questionnaire was used to assess participants' comprehension of informed consent. This was done immediately after consent had been obtained (at day 0) and at subsequent follow-up visits (days 7, 14, 21 and 28). The acceptability and ease of use of the multimedia tool were assessed in focus groups. On day 0, the median comprehension score in the intervention arm was 64% compared with 40% in the control arm (P = 0.042). The difference remained significant at all follow-up visits. Poorer comprehension was independently associated with female sex (odds ratio, OR: 0.29; 95% confidence interval, CI: 0.12-0.70) and residing in Jahaly rather than Basse province (OR: 0.33; 95% CI: 0.13-0.82). There was no significant independent association with educational level. The risk that a participant's comprehension score would drop to half of the initial value was lower in the intervention arm (hazard ratio 0.22, 95% CI: 0.16-0.31). Overall, 70% (42/60) of focus group participants from the intervention arm found the multimedia tool clear and easy to understand. A multimedia informed consent tool significantly improved comprehension and retention of consent information by research participants with low levels of literacy.

  8. The Prospect of Neutron Scattering in The 21st Century : A Powerful Tool For Materials Research

    International Nuclear Information System (INIS)

    E-Kartini

    2007-01-01

    Over the last 60 years research reactors (RRs) have played an important role in technological and socio-economical development of mankind, such as radioisotope production for medicine, industry, research and education. Neutron scattering has been widely used for research and development in materials science. The prospect of neutron scattering as a powerful tool for materials research is increasing in the 21 st century. This can be seen from the investment of several new neutron sources all over the world such as the Spallation Neutron Source (SNS) in USA, the Japan Proton Accelerator Complex (JPARC) in Japan, the new OPAL Reactor in Australia, and some upgrading to the existing sources at ISIS, Rutherford Appleton Laboratory, UK; Institute of Laue Langevin (ILL) in Grenoble, France and Berlin Reactor, Germany. Developing countries with moderate flux research reactor have also been involved in this technique, such as India, Malaysia and Indonesia The Siwabessy Multipurpose Reactor in Serpong, Indonesia that also produces thermal neutron has contributed to the research and development in the Asia Pacific Region. However,the international joint research among those countries plays an important role on optimizing the results. (author)

  9. The Prospect of Neutron Scattering In the 21st Century: A Powerful Tool for Materials Research

    Directory of Open Access Journals (Sweden)

    E. Kartini

    2007-07-01

    Full Text Available Over the last 60 years research reactors (RRs have played an important role in technological and socio-economical development of mankind, such as radioisotope production for medicine, industry, research and education. Neutron scattering has been widely used for research and development in materials science. The prospect of neutron scattering as a powerful tool for materials research is increasing in the 21st century. This can be seen from the investment of several new neutron sources all over the world such as the Spallation Neutron Source (SNS in USA, the Japan Proton Accelerator Complex (JPARC in Japan, the new OPAL Reactor in Australia, and some upgrading to the existing sources at ISIS, Rutherford Appleton Laboratory, UK; Institute of Laue Langevin (ILL in Grenoble, France and Berlin Reactor, Germany. Developing countries with moderate flux research reactor have also been involved in this technique, such as India, Malaysia and Indonesia. The Siwabessy Multipurpose Reactor in Serpong, Indonesia that also produces thermal neutron has contributed to the research and development in the Asia Pacific Region. However, the international joint research among those countries plays an important role on optimizing the results.

  10. Ubuntunet Alliance: A Collaborative Research Platform for Sharing of Technological Tools for Eradication of Brain Drain

    Directory of Open Access Journals (Sweden)

    Jameson Mbale

    2012-12-01

    Full Text Available The UbuntuNet Alliance Alliance is well-placed to facilitate interaction between education and research institutions and the African academic and researcher in the Diaspora so that together they can strengthen research that will exploit new technological tools and increase the industrial base. It is envisaged that the Alliance will become an important vehicle for linkages that will facilitate repatriation of scientific knowledge and skills to Africa and even help reduce and eventually eradicate the brain drain which has taken so many excellent intellectuals to the developed world. As organisational vehicles for inter-institutional collaboration both established and emerging NRENs can play a critical role in reversing these trends and in mitigating what appears to be the negative impact of the brain drain.

  11. Citizen Science as a Tool for Scientific Research and Societal Benefit at NASA

    Science.gov (United States)

    Kaminski, Amy

    2018-01-01

    NASA's strategic goals include advancing knowledge and opportunity in space and improving life on Earth. We support these goals through extensive programs in space and Earth science research accomplished via space-based missions and research funding. NASA's "system" is configured to conduct science using (1) in-house personnel and (2) grants, contracts, and agreements with external entities (academia, industry, international space agencies.

  12. Nucleic acids-based tools for ballast water surveillance, monitoring, and research

    Science.gov (United States)

    Darling, John A.; Frederick, Raymond M.

    2018-03-01

    Understanding the risks of biological invasion posed by ballast water-whether in the context of compliance testing, routine monitoring, or basic research-is fundamentally an exercise in biodiversity assessment, and as such should take advantage of the best tools available for tackling that problem. The past several decades have seen growing application of genetic methods for the study of biodiversity, driven in large part by dramatic technological advances in nucleic acids analysis. Monitoring approaches based on such methods have the potential to increase dramatically sampling throughput for biodiversity assessments, and to improve on the sensitivity, specificity, and taxonomic accuracy of traditional approaches. The application of targeted detection tools (largely focused on PCR but increasingly incorporating novel probe-based methodologies) has led to a paradigm shift in rare species monitoring, and such tools have already been applied for early detection in the context of ballast water surveillance. Rapid improvements in community profiling approaches based on high throughput sequencing (HTS) could similarly impact broader efforts to catalogue biodiversity present in ballast tanks, and could provide novel opportunities to better understand the risks of biotic exchange posed by ballast water transport-and the effectiveness of attempts to mitigate those risks. These various approaches still face considerable challenges to effective implementation, depending on particular management or research needs. Compliance testing, for instance, remains dependent on accurate quantification of viable target organisms; while tools based on RNA detection show promise in this context, the demands of such testing require considerable additional investment in methods development. In general surveillance and research contexts, both targeted and community-based approaches are still limited by various factors: quantification remains a challenge (especially for taxa in larger size

  13. Intercropping with white lupin (Lupinus albus L.); a promising tool for phytoremediation and phytomining research

    Science.gov (United States)

    Wiche, Oliver; Székely, Balazs; Moschner, Christin; Heilmeier, Hermann

    2015-04-01

    In recent studies root-soil interactions of white lupine (Lupinus albus L.) have drawn special attention to researchers due to its particularly high potential to increase bioavailability of phosphorous (P) and trace nutrients in soils. In mixed cultures, white lupine has the ability to mobilize P and trace nutrients in soil in excess of its own need and make this excess available for other intercropped companion species. While improved acquisition of P and improved yield parameters have mostly been documented in cereal-lupine intercrops, compared to sole crops, only a few recent studies have evidenced similar effects for trace elements e.g. Fe, Zn and Mn. In this preliminary study we tried to obtain more information about the mobilization of trace elements due to intercropping under field conditions. We hypothesize, that processes that lead to a better acquisition of trace nutrients might also affect other trace elements what could be useful for phytoremediation and phytomining research. Here we report the results of a semi-field experiment were we investigated the effects of an intercropping of white lupine with oat (Avena sativa L.) on the concentrations of trace metals in shoots of oat. We investigated the effects on 12 trace elements, including 4 elements with relevance for plant nutrition (P, Fe, Mn, Zn) and 8 trace elements, belonging to the group of metalloids, lanthanides and actinides with high relevance in phytoremediation (Cd, Pb Th, U) and phytomining research (Sc, La, Nd, Ge). The experiment was carried out on a semi-field lysimer at the off-site soil recycling and remediation center in Hirschfeld (Saxony, Germany). To test the intercropping-dependent mobilization of trace metals in soil and enhanced uptake of elements by oat, white lupine and oat were cultivated on 20 plots (4 m² each) in monocultures and mixed cultures and two different white lupin /oat-ratios (11% and 33%, respectively) applying various treatments. The geometrical arrangement of

  14. Magnetoencephalography as a Tool in Psychiatric Research: Current Status and Perspective.

    Science.gov (United States)

    Uhlhaas, Peter J; Liddle, Peter; Linden, David E J; Nobre, Anna C; Singh, Krish D; Gross, Joachim

    2017-04-01

    The application of neuroimaging to provide mechanistic insights into circuit dysfunctions in major psychiatric conditions and the development of biomarkers are core challenges in current psychiatric research. We propose that recent technological and analytic advances in magnetoencephalography (MEG), a technique that allows measurement of neuronal events directly and noninvasively with millisecond resolution, provides novel opportunities to address these fundamental questions. Because of its potential in delineating normal and abnormal brain dynamics, we propose that MEG provides a crucial tool to advance our understanding of pathophysiological mechanisms of major neuropsychiatric conditions, such as schizophrenia, autism spectrum disorders, and the dementias. We summarize the mechanisms underlying the generation of MEG signals and the tools available to reconstruct generators and underlying networks using advanced source-reconstruction techniques. We then surveyed recent studies that have used MEG to examine aberrant rhythmic activity in neuropsychiatric disorders. This was followed by links with preclinical research that has highlighted possible neurobiological mechanisms, such as disturbances in excitation/inhibition parameters, that could account for measured changes in neural oscillations. Finally, we discuss challenges as well as novel methodological developments that could pave the way for widespread application of MEG in translational research with the aim of developing biomarkers for early detection and diagnosis.

  15. The DEDUCE Guided Query tool: providing simplified access to clinical data for research and quality improvement.

    Science.gov (United States)

    Horvath, Monica M; Winfield, Stephanie; Evans, Steve; Slopek, Steve; Shang, Howard; Ferranti, Jeffrey

    2011-04-01

    In many healthcare organizations, comparative effectiveness research and quality improvement (QI) investigations are hampered by a lack of access to data created as a byproduct of patient care. Data collection often hinges upon either manual chart review or ad hoc requests to technical experts who support legacy clinical systems. In order to facilitate this needed capacity for data exploration at our institution (Duke University Health System), we have designed and deployed a robust Web application for cohort identification and data extraction--the Duke Enterprise Data Unified Content Explorer (DEDUCE). DEDUCE is envisioned as a simple, web-based environment that allows investigators access to administrative, financial, and clinical information generated during patient care. By using business intelligence tools to create a view into Duke Medicine's enterprise data warehouse, DEDUCE provides a Guided Query functionality using a wizard-like interface that lets users filter through millions of clinical records, explore aggregate reports, and, export extracts. Researchers and QI specialists can obtain detailed patient- and observation-level extracts without needing to understand structured query language or the underlying database model. Developers designing such tools must devote sufficient training and develop application safeguards to ensure that patient-centered clinical researchers understand when observation-level extracts should be used. This may mitigate the risk of data being misunderstood and consequently used in an improper fashion. Copyright © 2010 Elsevier Inc. All rights reserved.

  16. The DEDUCE Guided Query Tool: Providing Simplified Access to Clinical Data for Research and Quality Improvement

    Science.gov (United States)

    Horvath, Monica M.; Winfield, Stephanie; Evans, Steve; Slopek, Steve; Shang, Howard; Ferranti, Jeffrey

    2011-01-01

    In many healthcare organizations, comparative effectiveness research and quality improvement (QI) investigations are hampered by a lack of access to data created as a byproduct of patient care. Data collection often hinges upon either manual chart review or ad hoc requests to technical experts who support legacy clinical systems. In order to facilitate this needed capacity for data exploration at our institution (Duke University Health System), we have designed and deployed a robust Web application for cohort identification and data extraction—the Duke Enterprise Data Unified Content Explorer (DEDUCE). DEDUCE is envisioned as a simple, web-based environment that allows investigators access to administrative, financial, and clinical information generated during patient care. By using business intelligence tools to create a view into Duke Medicine's enterprise data warehouse, DEDUCE provides a guided query functionality using a wizard-like interface that lets users filter through millions of clinical records, explore aggregate reports, and, export extracts. Researchers and QI specialists can obtain detailed patient- and observation-level extracts without needing to understand structured query language or the underlying database model. Developers designing such tools must devote sufficient training and develop application safeguards to ensure that patient-centered clinical researchers understand when observation-level extracts should be used. This may mitigate the risk of data being misunderstood and consequently used in an improper fashion. PMID:21130181

  17. Studying mechanism of radical reactions: From radiation to nitroxides as research tools

    Science.gov (United States)

    Maimon, Eric; Samuni, Uri; Goldstein, Sara

    2018-02-01

    Radicals are part of the chemistry of life, and ionizing radiation chemistry serves as an indispensable research tool for elucidation of the mechanism(s) underlying their reactions. The ever-increasing understanding of their involvement in diverse physiological and pathological processes has expanded the search for compounds that can diminish radical-induced damage. This review surveys the areas of research focusing on radical reactions and particularly with stable cyclic nitroxide radicals, which demonstrate unique antioxidative activities. Unlike common antioxidants that are progressively depleted under oxidative stress and yield secondary radicals, nitroxides are efficient radical scavengers yielding in most cases their respective oxoammonium cations, which are readily reduced back in the tissue to the nitroxide thus continuously being recycled. Nitroxides, which not only protect enzymes, cells, and laboratory animals from diverse kinds of biological injury, but also modify the catalytic activity of heme enzymes, could be utilized in chemical and biological systems serving as a research tool for elucidating mechanisms underlying complex chemical and biochemical processes.

  18. Signs of resistance: multimodality as a tool in higher education research

    DEFF Research Database (Denmark)

    Lueg, Klarissa

    2018-01-01

    internationalization, and in studies focusing on the agent level of higher education organizations. ML is argued to add to the diversity of methods within a social constructivist methodology. The author illustrates how ML is connected and/or different from kindred approaches. Pathways are proposed as to how......The purpose of this paper is to introduce Multimodal Landscaping (ML) as a conceptual framework, and to illustrate how this approach can be applied within the field of higher education research. It is argued that ML is a suitable tool, especially, in studies investigating university...

  19. [The stimulated recall method: a research tool applicable to learning at science museums].

    Science.gov (United States)

    Falcão, Douglas; Gilbert, John

    2005-01-01

    The article reports on preliminary research aimed at developing a methological tool applicable to studies of learning in informal educational settings. The study was conducted at two science museums, using a modified version of the stimulated recall method. Digital photographs replaced the traditional video in the final phase, during which eight interviews were conducted, with satisfactory results. The digital photos efficaciously and efficiently stimulated visitors to narrate their experiences and to convey the meanings they took with them from their interactions with the exhibits.

  20. Frontal affinity chromatography: A unique research tool for biospecific interaction that promotes glycobiology

    Science.gov (United States)

    KASAI, Kenichi

    2014-01-01

    Combination of bioaffinity and chromatography gave birth to affinity chromatography. A further combination with frontal analysis resulted in creation of frontal affinity chromatography (FAC). This new versatile research tool enabled detailed analysis of weak interactions that play essential roles in living systems, especially those between complex saccharides and saccharide-binding proteins. FAC now becomes the best method for the investigation of saccharide-binding proteins (lectins) from viewpoints of sensitivity, accuracy, and efficiency, and is contributing greatly to the development of glycobiology. It opened a door leading to deeper understanding of the significance of saccharide recognition in life. The theory is also concisely described. PMID:25169774

  1. Use and Evaluation of FCM as a Tool for Long Term Socio Ecological Research

    DEFF Research Database (Denmark)

    Wildenberg, Martin; Bachhofer, Michael; Isak, Kirsten Grovermann Qvist

    2014-01-01

    A halt in loss of biodiversity is an important issue in conservation management across Europe. As landscapes tend to be perceived as a combination of natural and social elements, and people’s values and attitudes, research supporting conservation management is dealing with landscapes as socio-eco......-ecological systems. As part of ALTER-Net, we applied FCM to five cases and subsequently evaluated the approach by means of a SWOT framework. This examined the strengths and weaknesses of, and the opportunities and threats to FCM when applied as a tool in conservation management....

  2. Developing a patient and family research advisory panel to include people with significant disease, multimorbidity and advanced age.

    Science.gov (United States)

    Portalupi, Laura B; Lewis, Carmen L; Miller, Carl D; Whiteman-Jones, Kerry L; Sather, Kay A; Nease, Donald E; Matlock, Daniel D

    2017-06-01

    People who have experienced illness due to significant disease, multimorbidity and/or advanced age are high utilizers of the health care system. Yet this population has had little formal opportunity to participate in guiding the health care research agenda, and few mechanisms exist for researchers to engage this population in an efficient way. We describe the process of developing a standing patient and family advisory panel to incorporate this population's voice into research in the USA. The panel was created at the University of Colorado. Preliminary panel development consisted of a needs assessment, information gathering and participant recruitment. We collected feedback from researchers who consulted with the panel and from panel members in order to better understand the experience from the patient and family member perspective. The patient and family research advisory panel consists of eight advisors who have experience with significant disease, multimorbidity and/or advanced age, two physicians and a program manager. The panel meets every other month for 2 hours with the main purpose of advising diverse researchers on health care studies. People with significant disease, multimorbidity and/or advanced age represent a growing demographic in the USA, and their engagement in research is essential as the model of health care delivery moves from volume to value. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  3. An Interactive Visualization Tool for Multi-channel Confocal Microscopy Data in Neurobiology Research

    Science.gov (United States)

    Wan, Yong; Otsuna, Hideo; Chien, Chi-Bin; Hansen, Charles

    2010-01-01

    Confocal microscopy is widely used in neurobiology for studying the three-dimensional structure of the nervous system. Confocal image data are often multi-channel, with each channel resulting from a different fluorescent dye or fluorescent protein; one channel may have dense data, while another has sparse; and there are often structures at several spatial scales: subneuronal domains, neurons, and large groups of neurons (brain regions). Even qualitative analysis can therefore require visualization using techniques and parameters fine-tuned to a particular dataset. Despite the plethora of volume rendering techniques that have been available for many years, the techniques standardly used in neurobiological research are somewhat rudimentary, such as looking at image slices or maximal intensity projections. Thus there is a real demand from neurobiologists, and biologists in general, for a flexible visualization tool that allows interactive visualization of multi-channel confocal data, with rapid fine-tuning of parameters to reveal the three-dimensional relationships of structures of interest. Together with neurobiologists, we have designed such a tool, choosing visualization methods to suit the characteristics of confocal data and a typical biologist’s workflow. We use interactive volume rendering with intuitive settings for multidimensional transfer functions, multiple render modes and multi-views for multi-channel volume data, and embedding of polygon data into volume data for rendering and editing. As an example, we apply this tool to visualize confocal microscopy datasets of the developing zebrafish visual system. PMID:19834225

  4. An interactive visualization tool for multi-channel confocal microscopy data in neurobiology research

    KAUST Repository

    Yong Wan,

    2009-11-01

    Confocal microscopy is widely used in neurobiology for studying the three-dimensional structure of the nervous system. Confocal image data are often multi-channel, with each channel resulting from a different fluorescent dye or fluorescent protein; one channel may have dense data, while another has sparse; and there are often structures at several spatial scales: subneuronal domains, neurons, and large groups of neurons (brain regions). Even qualitative analysis can therefore require visualization using techniques and parameters fine-tuned to a particular dataset. Despite the plethora of volume rendering techniques that have been available for many years, the techniques standardly used in neurobiological research are somewhat rudimentary, such as looking at image slices or maximal intensity projections. Thus there is a real demand from neurobiologists, and biologists in general, for a flexible visualization tool that allows interactive visualization of multi-channel confocal data, with rapid fine-tuning of parameters to reveal the three-dimensional relationships of structures of interest. Together with neurobiologists, we have designed such a tool, choosing visualization methods to suit the characteristics of confocal data and a typical biologist\\'s workflow. We use interactive volume rendering with intuitive settings for multidimensional transfer functions, multiple render modes and multi-views for multi-channel volume data, and embedding of polygon data into volume data for rendering and editing. As an example, we apply this tool to visualize confocal microscopy datasets of the developing zebrafish visual system.

  5. Finding research information on the web: how to make the most of Google and other free search tools.

    Science.gov (United States)

    Blakeman, Karen

    2013-01-01

    The Internet and the World Wide Web has had a major impact on the accessibility of research information. The move towards open access and development of institutional repositories has resulted in increasing amounts of information being made available free of charge. Many of these resources are not included in conventional subscription databases and Google is not always the best way to ensure that one is picking up all relevant material on a topic. This article will look at how Google's search engine works, how to use Google more effectively for identifying research information, alternatives to Google and will review some of the specialist tools that have evolved to cope with the diverse forms of information that now exist in electronic form.

  6. A Clinical Reasoning Tool for Virtual Patients: Design-Based Research Study.

    Science.gov (United States)

    Hege, Inga; Kononowicz, Andrzej A; Adler, Martin

    2017-11-02

    Clinical reasoning is a fundamental process medical students have to learn during and after medical school. Virtual patients (VP) are a technology-enhanced learning method to teach clinical reasoning. However, VP systems do not exploit their full potential concerning the clinical reasoning process; for example, most systems focus on the outcome and less on the process of clinical reasoning. Keeping our concept grounded in a former qualitative study, we aimed to design and implement a tool to enhance VPs with activities and feedback, which specifically foster the acquisition of clinical reasoning skills. We designed the tool by translating elements of a conceptual clinical reasoning learning framework into software requirements. The resulting clinical reasoning tool enables learners to build their patient's illness script as a concept map when they are working on a VP scenario. The student's map is compared with the experts' reasoning at each stage of the VP, which is technically enabled by using Medical Subject Headings, which is a comprehensive controlled vocabulary published by the US National Library of Medicine. The tool is implemented using Web technologies, has an open architecture that enables its integration into various systems through an open application program interface, and is available under a Massachusetts Institute of Technology license. We conducted usability tests following a think-aloud protocol and a pilot field study with maps created by 64 medical students. The results show that learners interact with the tool but create less nodes and connections in the concept map than an expert. Further research and usability tests are required to analyze the reasons. The presented tool is a versatile, systematically developed software component that specifically supports the clinical reasoning skills acquisition. It can be plugged into VP systems or used as stand-alone software in other teaching scenarios. The modular design allows an extension with new

  7. Pipe dream? Envisioning a grassroots Python ecosystem of open, common software tools and data access in support of river and coastal biogeochemical research (Invited)

    Science.gov (United States)

    Mayorga, E.

    2013-12-01

    Practical, problem oriented software developed by scientists and graduate students in domains lacking a strong software development tradition is often balkanized into the scripting environments provided by dominant, typically proprietary tools. In environmental fields, these tools include ArcGIS, Matlab, SAS, Excel and others, and are often constrained to specific operating systems. While this situation is the outcome of rational choices, it limits the dissemination of useful tools and their integration into loosely coupled frameworks that can meet wider needs and be developed organically by groups addressing their own needs. Open-source dynamic languages offer the advantages of an accessible programming syntax, a wealth of pre-existing libraries, multi-platform access, linkage to community libraries developed in lower level languages such as C or FORTRAN, and access to web service infrastructure. Python in particular has seen a large and increasing uptake in scientific communities, as evidenced by the continued growth of the annual SciPy conference. Ecosystems with distinctive physical structures and organization, and mechanistic processes that are well characterized, are both factors that have often led to the grass-roots development of useful code meeting the needs of a range of communities. In aquatic applications, examples include river and watershed analysis tools (River Tools, Taudem, etc), and geochemical modules such as CO2SYS, PHREEQ and LOADEST. I will review the state of affairs and explore the potential offered by a Python tool ecosystem in supporting aquatic biogeochemistry and water quality research. This potential is multi-faceted and broadly involves accessibility to lone grad students, access to a wide community of programmers and problem solvers via online resources such as StackExchange, and opportunities to leverage broader cyberinfrastructure efforts and tools, including those from widely different domains. Collaborative development of such

  8. Twitter Chats as a Research Tool: A Study of Young Adult Financial Decisions

    Directory of Open Access Journals (Sweden)

    Barbara O’Neill

    2018-02-01

    Full Text Available Many researchers collect online survey data because it is cost-effective and less time-consuming than traditional research methods. This paper describes Twitter chats as a research tool vis-à-vis two other online research methods: providing links to electronic surveys to respondents and use of commercially available survey panels through vendors with readily available respondents. Similar to a face-to-face focus group, Twitter chats provide a synchronous environment for participants to answer a structured series of questions and to respond to both the chat facilitator and each other. This paper also reports representative responses from a Twitter chat that explored financial decisions of young adults. The chat was sponsored by a multi-state group of land-grant university researchers, in cooperation with WiseBread, a personal finance website targeted to millennials, to recruit respondents for a more extensive month-long online survey about the financial decisions of young adults. The Twitter chat responses suggest that student loans were the top concern of participants, and debt and housing rounded out the top three concerns. The internet, both websites and social media, was the most frequently cited source of financial information. The article concludes with a discussion of lessons learned from the Twitter chat experience and suggestions for professional practice.

  9. Designing simulator tools for rail research: the case study of a train driving microworld.

    Science.gov (United States)

    Naweed, A; Hockey, G R J; Clarke, S D

    2013-05-01

    The microworld simulator paradigm is well established in the areas of ship-navigation and spaceflight, but has yet to be applied to rail. This paper presents a case study aiming to address this research gap, and describes the development of a train driving microworld as a tool to overcome some common research barriers. A theoretical framework for microworld design is tested and used to explore some key methodological issues and characteristics of train driving, enhancing theory development and providing a useful guideline for the designers of other collision-avoidance systems. A detailed description is given of the ATREIDES (Adaptive Train Research Enhanced Information Display & Environment Simulator) microworld, which simulates the work environment of a train driver in a high-speed passenger train. General indications of the testable driving scenarios that may be simulated are given, and an example of an ATREIDES-based study is presented to illustrate its applied research potential. The article concludes with a review of the design process, considers some strengths and limitations, and explores some future initiatives towards enhancing the systematic study of rail research in the human factors community. Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  10. Employment of Questionnaire as Tool for Effective Business Research Outcome: Problems and Challenges

    Directory of Open Access Journals (Sweden)

    ADENIYI AKINGBADE WAIDI

    2016-06-01

    Full Text Available Questionnaire has to do with questions designed to gather information or data for analysis. Questionnaire has to be adequate, simple, focused and related to the subject which the research is set to achieve and to test the hypotheses and questions that are formulated for the study. But many questionnaires are constructed and administered without following proper guideline which hinders there end result. This paper assesses some of the guides for constructing questionnaire as well as it uses and the extent to which it enhanced manager’s access to reliable data and information. Descriptive method is employed for the study. Findings revealed that poor or badly prepared questionnaire produce questionnaire that does not provide effective results. Managers and researchers that use such questionnaire hardly achieve their organisational and research objectives. The need for good, well prepared and adequate questionnaire is exemplified by its being the primary tool for analytical research. The study recommends that questionnaire be properly prepared for effective research outcome.

  11. Diagnostic tools in PEM fuel cell research: Part II. Physical/chemical methods

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Jinfeng; Zi Yuan, Xiao; Wang, Haijiang; Martin, Jonathan J.; Zhang, Jiujun [Institute for Fuel Cell Innovation, National Research Council (Canada); Blanco, Mauricio [Institute for Fuel Cell Innovation, National Research Council (Canada); Department of Chemical and Biological Engineering, University of British Columbia, Vancouver, BC (Canada)

    2008-03-15

    To meet the power density, reliability and cost requirements that will enable a widespread use of fuel cells, many research activities focus on an understanding of the thermodynamics as well as the fluid mechanical and electrochemical processes within a fuel cell. To date, a wide range of experimental diagnostics is imperative not only to help a fundamental understanding of fuel cell dynamics but also to provide benchmark-quality data for modeling research. This paper reviews various tools for diagnosing polymer electrolyte membrane (PEM) fuel cells and stacks, and attempts to incorporate the most recent technical advances in PEM fuel cell diagnosis. In Part I of the review we covered electrochemical techniques. In Part II, we review various physical/chemical methods and outline the principle, experimental implementation and data processing of each technique. Capabilities and weaknesses of these techniques are also discussed. (author)

  12. Facebook as a research tool for the social sciences: Opportunities, challenges, ethical considerations, and practical guidelines.

    Science.gov (United States)

    Kosinski, Michal; Matz, Sandra C; Gosling, Samuel D; Popov, Vesselin; Stillwell, David

    2015-09-01

    Facebook is rapidly gaining recognition as a powerful research tool for the social sciences. It constitutes a large and diverse pool of participants, who can be selectively recruited for both online and offline studies. Additionally, it facilitates data collection by storing detailed records of its users' demographic profiles, social interactions, and behaviors. With participants' consent, these data can be recorded retrospectively in a convenient, accurate, and inexpensive way. Based on our experience in designing, implementing, and maintaining multiple Facebook-based psychological studies that attracted over 10 million participants, we demonstrate how to recruit participants using Facebook, incentivize them effectively, and maximize their engagement. We also outline the most important opportunities and challenges associated with using Facebook for research, provide several practical guidelines on how to successfully implement studies on Facebook, and finally, discuss ethical considerations. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

  13. [Conflict of interest disclosure as a tool to improve the reliability of research].

    Science.gov (United States)

    Soto Subiabre, Mauricio

    2016-08-01

    Conflicts of interest are situations in which professional judgment concerning a primary interest, tends to be influenced by a secondary interest. These conflicts could compromise the reliability of biomedical research and result in the dissemination of biased results. Therefore, it is essential to protect the integrity of them, because this information could be used in the development of health policy, medical education and clinical decision making. Conflicts of interest disclosure, is a bioethical tool that contributes to transparent these conflicts, but it is used inappropriately and insufficiently. To be useful, it must be based on clear principles, it should help to perform a critical analysis and should be considered in the design of every research project. This review is an analysis of the conflicts of interest disclosure, its scope and limitations and should contribute to develop a greater awareness of its importance.

  14. Handbook of bibliometric indicators quantitative tools for studying and evaluating research

    CERN Document Server

    Todeschini, Roberto

    2016-01-01

    At last, the first systematic guide to the growing jungle of citation indices and other bibliometric indicators. Written with the aim of providing a complete and unbiased overview of all available statistical measures for scientific productivity, the core of this reference is an alphabetical dictionary of indices and other algorithms used to evaluate the importance and impact of researchers and their institutions. In 150 major articles, the authors describe all indices in strictly mathematical terms without passing judgement on their relative merit. From widely used measures, such as the journal impact factor or the h-index, to highly specialized indices, all indicators currently in use in the sciences and humanities are described, and their application explained. The introductory section and the appendix contain a wealth of valuable supporting information on data sources, tools and techniques for bibliometric and scientometric analysis - for individual researchers as well as their funders and publishers.

  15. Rapidly Re-Configurable Flight Simulator Tools for Crew Vehicle Integration Research and Design

    Science.gov (United States)

    Pritchett, Amy R.

    2002-01-01

    While simulation is a valuable research and design tool, the time and difficulty required to create new simulations (or re-use existing simulations) often limits their application. This report describes the design of the software architecture for the Reconfigurable Flight Simulator (RFS), which provides a robust simulation framework that allows the simulator to fulfill multiple research and development goals. The core of the architecture provides the interface standards for simulation components, registers and initializes components, and handles the communication between simulation components. The simulation components are each a pre-compiled library 'plugin' module. This modularity allows independent development and sharing of individual simulation components. Additional interfaces can be provided through the use of Object Data/Method Extensions (OD/ME). RFS provides a programmable run-time environment for real-time access and manipulation, and has networking capabilities using the High Level Architecture (HLA).

  16. The Virtual Museum for Meteorites: an Online Tool for Researchers Educators and Students

    Science.gov (United States)

    Madiedo, J. M.

    2013-09-01

    The Virtual Museum for Meteorites (Figure 1) was created as a tool for students, educators and researchers [1, 2]. One of the aims of this online resource is to promote the interest in meteorites. Thus, the role of meteorites in education and outreach is fundamental, as these are very valuable tools to promote the public's interest in Astronomy and Planetary Sciences. Meteorite exhibitions reveal the fascination of students, educators and even researchers for these extraterrestrial rocks and how these can explain many key questions origin and evolution of our Solar System. However, despite the efforts related to the origin and evolution of our Solar System. However, despite the efforts of private collectors, museums and other institutions to organize meteorite exhibitions, the reach of these is usually limited. The Virtual Museum for Meteorites takes advantage of HTML and related technologies to overcome local boundaries and offer its contents for a global audience. A description of the recent developments performed in the framework of this virtual museum is given in this work.

  17. Communications tools in research projects to support Semi and Non Structured Information

    Directory of Open Access Journals (Sweden)

    Astrid Jaime

    2005-06-01

    Full Text Available Innovation and thus the production of knowledge becomes a factor of competitiveness. In this context quality management could be complemented by knowledge management to aim the improvement of knowledge production by research activities process. To this end, after describing knowledge and informa-tion typologies in engineering activities, a knowledge man-agement system is proposed. The goal is to support: (1 Semi-Structured Information (e.g. reports, etc. thanks to the BASIC-Lab tool functions, which are based on attributing points of view and annotations to documents and document zones, and (2 Non-Structured Information (such as mail, dialogues, etc., thanks to MICA-Graph approach which intends to support ex-change of technical messages that concerns common resolution of research problems within project teams and to capitalise relevant knowledge. For the both approaches, prototype tools have been developed and evaluated, primarily to feed back with manufacturing knowledge in the EADS industrial envi-ronment.

  18. Intention, Principle, Outputs and Aims of the Experimental Pavilion Research of Building Envelopes Including Windows for Wooden Buildings

    Science.gov (United States)

    Štaffenová, Daniela; Rybárik, Ján; Jakubčík, Miroslav

    2017-06-01

    The aim of experimental research in the area of exterior walls and windows suitable for wooden buildings was to build special pavilion laboratories. These laboratories are ideally isolated from the surrounding environment, airtight and controlled by the constant internal climate. The principle of experimental research is measuring and recording of required physical parameters (e.g. temperature or relative humidity). This is done in layers of experimental fragment sections in the direction from exterior to interior, as well as in critical places by stable interior and real exterior climatic conditions. The outputs are evaluations of experimental structures behaviour during the specified time period, possibly during the whole year by stable interior and real exterior boundary conditions. The main aim of this experimental research is processing of long-term measurements of experimental structures and the subsequent analysis. The next part of the research consists of collecting measurements obtained with assistance of the experimental detached weather station, analysis, evaluation for later setting up of reference data set for the research locality, from the point of view of its comparison to the data sets from Slovak Hydrometeorological Institute (SHMU) and to localities with similar climate conditions. Later on, the data sets could lead to recommendations for design of wooden buildings.

  19. A Survey of British Research in Audio-Visual Aids, Supplement No. 2, 1974. (Including Cumulative Index 1945-1974).

    Science.gov (United States)

    Rodwell, Susie, Comp.

    The second supplement to the new (1972) edition of the Survey of Research in Audiovisual Aids carried out in Great Britain covers the year 1974. Ten separate sections cover the areas of projected media, non-projected media, sound media, radio, moving pictures, television, teaching machines and programed learning, computer-assisted instruction,…

  20. Including a Service Learning Educational Research Project in a Biology Course-II: Assessing Community Awareness of Legionnaires' Disease?

    Science.gov (United States)

    Abu-Shakra, Amal

    2012-01-01

    For a university service learning educational research project addressing Legionnaires' disease (LD), a Yes/No questionnaire on community awareness of LD was developed and distributed in an urban community in North Carolina, USA. The 456 questionnaires completed by the participants were sorted into yes and no sets based on responses obtained to…

  1. Hallucinogens and Dissociative Drugs, Including LSD, PCP, Ketamine, Dextromethorphan. National Institute on Drug Abuse Research Report Series.

    Science.gov (United States)

    National Inst. on Drug Abuse (DHHS/PHS), Rockville, MD.

    Research is developing a clearer picture of the dangers of mind-altering drugs. The goal of this report is to present the latest information to providers to help them strengthen their prevention and treatment efforts. A description is presented of dissociative drugs, and consideration is given as to why people take hallucinogens. The physical…

  2. A tool for exploring space-time patterns : an animation user research

    Directory of Open Access Journals (Sweden)

    Ogao Patrick J

    2006-08-01

    Full Text Available Abstract Background Ever since Dr. John Snow (1813–1854 used a case map to identify water well as the source of a cholera outbreak in London in the 1800s, the use of spatio-temporal maps have become vital tools in a wide range of disease mapping and control initiatives. The increasing use of spatio-temporal maps in these life-threatening sectors warrants that they are accurate, and easy to interpret to enable prompt decision making by health experts. Similar spatio-temporal maps are observed in urban growth and census mapping – all critical aspects a of a country's socio-economic development. In this paper, a user test research was carried out to determine the effectiveness of spatio-temporal maps (animation in exploring geospatial structures encompassing disease, urban and census mapping. Results Three types of animation were used, namely; passive, interactive and inference-based animation, with the key differences between them being on the level of interactivity and complementary domain knowledge that each offers to the user. Passive animation maintains the view only status. The user has no control over its contents and dynamic variables. Interactive animation provides users with the basic media player controls, navigation and orientation tools. Inference-based animation incorporates these interactive capabilities together with a complementary automated intelligent view that alerts users to interesting patterns, trends or anomalies that may be inherent in the data sets. The test focussed on the role of animation passive and interactive capabilities in exploring space-time patterns by engaging test-subjects in thinking aloud evaluation protocol. The test subjects were selected from a geoinformatics (map reading, interpretation and analysis abilities background. Every test-subject used each of the three types of animation and their performances for each session assessed. The results show that interactivity in animation is a preferred

  3. Laboratory directed research and development final report: Intelligent tools for on-machine acceptance of precision machined components

    Energy Technology Data Exchange (ETDEWEB)

    Christensen, N.G.; Harwell, L.D.; Hazelton, A.

    1997-02-01

    On-Machine Acceptance (OMA) is an agile manufacturing concept being developed for machine tools at SNL. The concept behind OMA is the integration of product design, fabrication, and qualification processes by using the machining center as a fabrication and inspection tool. This report documents the final results of a Laboratory Directed Research and Development effort to qualify OMA.

  4. Action-Research and Food and Nutrition Security: A School Experience Mediated by Conceptual Graphic Representation Tool

    Science.gov (United States)

    Graebner, Ivete Teresinha; de Souza, Elizabeth Maria Tala; Saito, Carlos Hiroo

    2009-01-01

    This study deals with the development of a graphic representation tool as a way to support educational planning in an elementary school in the rural area of Brasilia (Brazil's capital), aiming at the implementation of an integrated action-research project focusing on hunger and nutrition. The graphic tool made it possible to promote…

  5. Applying the Bundle-Move Connection Approach to the Development of an Online Writing Support Tool for Research Articles

    Science.gov (United States)

    Mizumoto, Atsushi; Hamatani, Sawako; Imao, Yasuhiro

    2017-01-01

    With advances in information and computer technology, genre-based writing pedagogy has developed greatly in recent years. In order to further this growth in technology-enhanced genre writing pedagogy, this study developed a data-driven and theory-based practical support tool for writing research articles. This web-based, innovative tool, powered…

  6. Evaluating the Development of Science Research Skills in Work-Integrated Learning through the Use of Workplace Science Tools

    Science.gov (United States)

    McCurdy, Susan M.; Zegwaard, Karsten E.; Dalgety, Jacinta

    2013-01-01

    Concept understanding, the development of analytical skills and a research mind set are explored through the use of academic tools common in a tertiary science education and relevant work-integrated learning (WIL) experiences. The use and development of the tools; laboratory book, technical report, and literature review are examined by way of…

  7. Evidence & Gap Maps: A tool for promoting evidence informed policy and strategic research agendas.

    Science.gov (United States)

    Snilstveit, Birte; Vojtkova, Martina; Bhavsar, Ami; Stevenson, Jennifer; Gaarder, Marie

    2016-11-01

    A range of organizations are engaged in the production of evidence on the effects of health, social, and economic development programs on human welfare outcomes. However, evidence is often scattered around different databases, web sites, and the gray literature and is often presented in inaccessible formats. Lack of overview of the evidence in a specific field can be a barrier to the use of existing research and prevent efficient use of limited resources for new research. Evidence & Gap Maps (EGMs) aim to address these issues and complement existing synthesis and mapping approaches. EGMs are a new addition to the tools available to support evidence-informed policymaking. To provide an accessible resource for researchers, commissioners, and decision makers, EGMs provide thematic collections of evidence structured around a framework which schematically represents the types of interventions and outcomes of relevance to a particular sector. By mapping the existing evidence using this framework, EGMs provide a visual overview of what we know and do not know about the effects of different programs. They make existing evidence available, and by providing links to user-friendly summaries of relevant studies, EGMs can facilitate the use of existing evidence for decision making. They identify key "gaps" where little or no evidence from impact evaluations and systematic reviews is available and can be a valuable resource to inform a strategic approach to building the evidence base in a particular sector. The article will introduce readers to the concept and methods of EGMs and present a demonstration of the EGM tool using existing examples. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. iSRAP – a one-touch research tool for rapid profiling of small RNA-seq data

    Science.gov (United States)

    Quek, Camelia; Jung, Chol-hee; Bellingham, Shayne A.; Lonie, Andrew; Hill, Andrew F.

    2015-01-01

    Small non-coding RNAs have been significantly recognized as the key modulators in many biological processes, and are emerging as promising biomarkers for several diseases. These RNA species are transcribed in cells and can be packaged in extracellular vesicles, which are small vesicles released from many biotypes, and are involved in intercellular communication. Currently, the advent of next-generation sequencing (NGS) technology for high-throughput profiling has further advanced the biological insights of non-coding RNA on a genome-wide scale and has become the preferred approach for the discovery and quantification of non-coding RNA species. Despite the routine practice of NGS, the processing of large data sets poses difficulty for analysis before conducting downstream experiments. Often, the current analysis tools are designed for specific RNA species, such as microRNA, and are limited in flexibility for modifying parameters for optimization. An analysis tool that allows for maximum control of different software is essential for drawing concrete conclusions for differentially expressed transcripts. Here, we developed a one-touch integrated small RNA analysis pipeline (iSRAP) research tool that is composed of widely used tools for rapid profiling of small RNAs. The performance test of iSRAP using publicly and in-house available data sets shows its ability of comprehensive profiling of small RNAs of various classes, and analysis of differentially expressed small RNAs. iSRAP offers comprehensive analysis of small RNA sequencing data that leverage informed decisions on the downstream analyses of small RNA studies, including extracellular vesicles such as exosomes. PMID:26561006

  9. iSRAP - a one-touch research tool for rapid profiling of small RNA-seq data.

    Science.gov (United States)

    Quek, Camelia; Jung, Chol-Hee; Bellingham, Shayne A; Lonie, Andrew; Hill, Andrew F

    2015-01-01

    Small non-coding RNAs have been significantly recognized as the key modulators in many biological processes, and are emerging as promising biomarkers for several diseases. These RNA species are transcribed in cells and can be packaged in extracellular vesicles, which are small vesicles released from many biotypes, and are involved in intercellular communication. Currently, the advent of next-generation sequencing (NGS) technology for high-throughput profiling has further advanced the biological insights of non-coding RNA on a genome-wide scale and has become the preferred approach for the discovery and quantification of non-coding RNA species. Despite the routine practice of NGS, the processing of large data sets poses difficulty for analysis before conducting downstream experiments. Often, the current analysis tools are designed for specific RNA species, such as microRNA, and are limited in flexibility for modifying parameters for optimization. An analysis tool that allows for maximum control of different software is essential for drawing concrete conclusions for differentially expressed transcripts. Here, we developed a one-touch integrated small RNA analysis pipeline (iSRAP) research tool that is composed of widely used tools for rapid profiling of small RNAs. The performance test of iSRAP using publicly and in-house available data sets shows its ability of comprehensive profiling of small RNAs of various classes, and analysis of differentially expressed small RNAs. iSRAP offers comprehensive analysis of small RNA sequencing data that leverage informed decisions on the downstream analyses of small RNA studies, including extracellular vesicles such as exosomes.

  10. Design of a Web-tool for diagnostic clinical trials handling medical imaging research.

    Science.gov (United States)

    Baltasar Sánchez, Alicia; González-Sistal, Angel

    2011-04-01

    New clinical studies in medicine are based on patients and controls using different imaging diagnostic modalities. Medical information systems are not designed for clinical trials employing clinical imaging. Although commercial software and communication systems focus on storage of image data, they are not suitable for storage and mining of new types of quantitative data. We sought to design a Web-tool to support diagnostic clinical trials involving different experts and hospitals or research centres. The image analysis of this project is based on skeletal X-ray imaging. It involves a computerised image method using quantitative analysis of regions of interest in healthy bone and skeletal metastases. The database is implemented with ASP.NET 3.5 and C# technologies for our Web-based application. For data storage, we chose MySQL v.5.0, one of the most popular open source databases. User logins were necessary, and access to patient data was logged for auditing. For security, all data transmissions were carried over encrypted connections. This Web-tool is available to users scattered at different locations; it allows an efficient organisation and storage of data (case report form) and images and allows each user to know precisely what his task is. The advantages of our Web-tool are as follows: (1) sustainability is guaranteed; (2) network locations for collection of data are secured; (3) all clinical information is stored together with the original images and the results derived from processed images and statistical analysis that enable us to perform retrospective studies; (4) changes are easily incorporated because of the modular architecture; and (5) assessment of trial data collected at different sites is centralised to reduce statistical variance.

  11. Validation of the 4D NCAT simulation tools for use in high-resolution x-ray CT research

    Science.gov (United States)

    Segars, W. P.; Mahesh, Mahadevappa; Beck, T.; Frey, E. C.; Tsui, B. M. W.

    2005-04-01

    We validate the computer-based simulation tools developed in our laboratory for use in high-resolution CT research. The 4D NURBS-based cardiac-torso (NCAT) phantom was developed to provide a realistic and flexible model of the human anatomy and physiology. Unlike current phantoms in CT, the 4D NCAT has the advantage, due to its design, that its organ shapes can be changed to realistically model anatomical variations and patient motion. To efficiently simulate high-resolution CT images, we developed a unique analytic projection algorithm (including scatter and quantum noise) to accurately calculate projections directly from the surface definition of the phantom given parameters defining the CT scanner and geometry. The projection data are reconstructed into CT images using algorithms developed in our laboratory. The 4D NCAT phantom contains a level of detail that is close to impossible to produce in a physical test object. We, therefore, validate our CT simulation tools and methods through a series of direct comparisons with data obtained experimentally using existing, simple physical phantoms at different doses and using different x-ray energy spectra. In each case, the first-order simulations were found to produce comparable results (<12%). We reason that since the simulations produced equivalent results using simple test objects, they should be able to do the same in more anatomically realistic conditions. We conclude that, with the ability to provide realistic simulated CT image data close to that from actual patients, the simulation tools developed in this work will have applications in a broad range of CT imaging research.

  12. Human factors issues and approaches in the spatial layout of a space station control room, including the use of virtual reality as a design analysis tool

    Science.gov (United States)

    Hale, Joseph P., II

    1994-01-01

    Human Factors Engineering support was provided for the 30% design review of the late Space Station Freedom Payload Control Area (PCA). The PCA was to be the payload operations control room, analogous to the Spacelab Payload Operations Control Center (POCC). This effort began with a systematic collection and refinement of the relevant requirements driving the spatial layout of the consoles and PCA. This information was used as input for specialized human factors analytical tools and techniques in the design and design analysis activities. Design concepts and configuration options were developed and reviewed using sketches, 2-D Computer-Aided Design (CAD) drawings, and immersive Virtual Reality (VR) mockups.

  13. Managing misaligned paternity findings in research including sickle cell disease screening in Kenya: 'consulting communities' to inform policy.

    Science.gov (United States)

    Marsh, Vicki; Kombe, Francis; Fitzpatrick, Ray; Molyneux, Sassy; Parker, Michael

    2013-11-01

    The management of misaligned paternity findings raises important controversy worldwide. It has mainly, however, been discussed in the context of high-income countries. Genetic and genomics research, with the potential to show misaligned paternity, are becoming increasingly common in Africa. During a genomics study in Kenya, a dilemma arose over testing and sharing information on paternal sickle cell disease status. This dilemma may be paradigmatic of challenges in sharing misaligned paternity findings in many research and health care settings. Using a deliberative approach to community consultation to inform research practice, we explored residents' views on paternal testing and sharing misaligned paternity information. Between December 2009 and November 2010, 63 residents in Kilifi County were engaged in informed deliberative small group discussions, structured to support normative reflection within the groups, with purposive selection to explore diversity. Analysis was based on a modified framework analysis approach, drawing on relevant social science and bioethics literature. The methods generated in-depth individual and group reflection on morally important issues and uncovered wide diversity in views and values. Fundamental and conflicting values emerged around the importance of family interests and openness, underpinned by disagreement on the moral implications of marital infidelity and withholding truth. Wider consideration of ethical issues emerging in these debates supports locally-held reasoning that paternal sickle cell testing should not be undertaken in this context, in contrast to views that testing should be done with or without the disclosure of misaligned paternity information. The findings highlight the importance of facilitating wider testing of family members of affected children, contingent on the development and implementation of national policies for the management of this inherited disorder. Their richness also illustrates the potential for

  14. Managing misaligned paternity findings in research including sickle cell disease screening in Kenya: ‘Consulting communities’ to inform policy☆

    Science.gov (United States)

    Marsh, Vicki; Kombe, Francis; Fitzpatrick, Ray; Molyneux, Sassy; Parker, Michael

    2013-01-01

    The management of misaligned paternity findings raises important controversy worldwide. It has mainly, however, been discussed in the context of high-income countries. Genetic and genomics research, with the potential to show misaligned paternity, are becoming increasingly common in Africa. During a genomics study in Kenya, a dilemma arose over testing and sharing information on paternal sickle cell disease status. This dilemma may be paradigmatic of challenges in sharing misaligned paternity findings in many research and health care settings. Using a deliberative approach to community consultation to inform research practice, we explored residents' views on paternal testing and sharing misaligned paternity information. Between December 2009 and November 2010, 63 residents in Kilifi County were engaged in informed deliberative small group discussions, structured to support normative reflection within the groups, with purposive selection to explore diversity. Analysis was based on a modified framework analysis approach, drawing on relevant social science and bioethics literature. The methods generated in-depth individual and group reflection on morally important issues and uncovered wide diversity in views and values. Fundamental and conflicting values emerged around the importance of family interests and openness, underpinned by disagreement on the moral implications of marital infidelity and withholding truth. Wider consideration of ethical issues emerging in these debates supports locally-held reasoning that paternal sickle cell testing should not be undertaken in this context, in contrast to views that testing should be done with or without the disclosure of misaligned paternity information. The findings highlight the importance of facilitating wider testing of family members of affected children, contingent on the development and implementation of national policies for the management of this inherited disorder. Their richness also illustrates the potential for

  15. Air Enquirer's multi-sensor boxes as a tool for High School Education and Atmospheric Research

    Science.gov (United States)

    Morguí, Josep-Anton; Font, Anna; Cañas, Lidia; Vázquez-García, Eusebi; Gini, Andrea; Corominas, Ariadna; Àgueda, Alba; Lobo, Agustin; Ferraz, Carlos; Nofuentes, Manel; Ulldemolins, Delmir; Roca, Alex; Kamnang, Armand; Grossi, Claudia; Curcoll, Roger; Batet, Oscar; Borràs, Silvia; Occhipinti, Paola; Rodó, Xavier

    2016-04-01

    An educational tool was designed with the aim of making more comprehensive the research done on Greenhouse Gases (GHGs) in the ClimaDat Spanish network of atmospheric observation stations (www.climadat.es). This tool is called Air Enquirer and it consist of a multi-sensor box. It is envisaged to build more than two hundred boxes to yield them to the Spanish High Schools through the Education department (www.educaixa.com) of the "Obra Social 'La Caixa'", who funds this research. The starting point for the development of the Air Enquirers was the experience at IC3 (www.ic3.cat) in the CarboSchools+ FP7 project (www.carboschools.cat, www.carboschools.eu). The Air Enquirer's multi-sensor box is based in Arduino's architecture and contains sensors for CO2, temperature, relative humidity, pressure, and both infrared and visible luminance. The Air Enquirer is designed for taking continuous measurements. Every Air Enquirer ensemble of measurements is used to convert values to standard units (water content in ppmv, and CO2 in ppmv_dry). These values are referred to a calibration made with Cavity Ring Down Spectrometry (Picarro®) under different temperature, pressure, humidity and CO2 concentrations. Multiple sets of Air Enquirers are intercalibrated for its use in parallel during the experiments. The different experiments proposed to the students will be outdoor (observational) or indoor (experimental, in the lab) focusing on understanding the biogeochemistry of GHGs in the ecosystems (mainly CO2), the exchange (flux) of gases, the organic matter production, respiration and decomposition processes, the influence of the anthropogenic activities on the gases (and particles) exchanges, and their interaction with the structure and composition of the atmosphere (temperature, water content, cooling and warming processes, radiative forcing, vertical gradients and horizontal patterns). In order to ensure Air Enquirers a high-profile research performance the experimental designs

  16. Energy Dispersive X-ray (EDX) microanalysis: A powerful tool in biomedical research and diagnosis.

    Science.gov (United States)

    Scimeca, Manuel; Bischetti, Simone; Lamsira, Harpreet Kaur; Bonfiglio, Rita; Bonanno, Elena

    2018-03-15

    The Energy Dispersive X-ray (EDX) microanalysis is a technique of elemental analysis associated to electron microscopy based on the generation of characteristic Xrays that reveals the presence of elements present in the specimens. The EDX microanalysis is used in different biomedical fields by many researchers and clinicians. Nevertheless, most of the scientific community is not fully aware of its possible applications. The spectrum of EDX microanalysis contains both semi-qualitative and semi-quantitative information. EDX technique is made useful in the study of drugs, such as in the study of drugs delivery in which the EDX is an important tool to detect nanoparticles (generally, used to improve the therapeutic performance of some chemotherapeutic agents). EDX is also used in the study of environmental pollution and in the characterization of mineral bioaccumulated in the tissues. In conclusion, the EDX can be considered as a useful tool in all works that require element determination, endogenous or exogenous, in the tissue, cell or any other sample.

  17. How should we assess knowledge translation in research organizations; designing a knowledge translation self-assessment tool for research institutes (SATORI).

    Science.gov (United States)

    Gholami, Jaleh; Majdzadeh, Reza; Nedjat, Saharnaz; Nedjat, Sima; Maleki, Katayoun; Ashoorkhani, Mahnaz; Yazdizadeh, Bahareh

    2011-02-22

    The knowledge translation self-assessment tool for research institutes (SATORI) was designed to assess the status of knowledge translation in research institutes. The objective was, to identify the weaknesses and strengths of knowledge translation in research centres and faculties associated with Tehran University of Medical Sciences (TUMS). The tool, consisting of 50 statements in four main domains, was used in 20 TUMS-affiliated research centres and departments after its reliability was established. It was completed in a group discussion by the members of the research council, researchers and research users' representatives from each centre and/or department. The mean score obtained in the four domains of 'The question of research', 'Knowledge production', 'Knowledge transfer' and 'Promoting the use of evidence' were 2.26, 2.92, 2 and 1.89 (out of 5) respectively.Nine out of 12 interventional priorities with the lowest quartile score were related to knowledge transfer resources and strategies, whereas eight of them were in the highest quartile and related to 'The question of research' and 'Knowledge production'. The self-assessment tool identifies the gaps in capacity and infrastructure of knowledge translation support within research organizations. Assessment of research institutes using SATORI pointed out that strengthening knowledge translation through provision of financial support for knowledge translation activities, creating supportive and facilitating infrastructures, and facilitating interactions between researchers and target audiences to exchange questions and research findings are among the priorities of research centres and/or departments.

  18. On the Use of EEG or MEG Brain Imaging Tools in Neuromarketing Research

    Directory of Open Access Journals (Sweden)

    Giovanni Vecchiato

    2011-01-01

    Full Text Available Here we present an overview of some published papers of interest for the marketing research employing electroencephalogram (EEG and magnetoencephalogram (MEG methods. The interest for these methodologies relies in their high-temporal resolution as opposed to the investigation of such problem with the functional Magnetic Resonance Imaging (fMRI methodology, also largely used in the marketing research. In addition, EEG and MEG technologies have greatly improved their spatial resolution in the last decades with the introduction of advanced signal processing methodologies. By presenting data gathered through MEG and high resolution EEG we will show which kind of information it is possible to gather with these methodologies while the persons are watching marketing relevant stimuli. Such information will be related to the memorization and pleasantness related to such stimuli. We noted that temporal and frequency patterns of brain signals are able to provide possible descriptors conveying information about the cognitive and emotional processes in subjects observing commercial advertisements. These information could be unobtainable through common tools used in standard marketing research. We also show an example of how an EEG methodology could be used to analyze cultural differences between fruition of video commercials of carbonated beverages in Western and Eastern countries.

  19. On the use of EEG or MEG brain imaging tools in neuromarketing research.

    Science.gov (United States)

    Vecchiato, Giovanni; Astolfi, Laura; De Vico Fallani, Fabrizio; Toppi, Jlenia; Aloise, Fabio; Bez, Francesco; Wei, Daming; Kong, Wanzeng; Dai, Jounging; Cincotti, Febo; Mattia, Donatella; Babiloni, Fabio

    2011-01-01

    Here we present an overview of some published papers of interest for the marketing research employing electroencephalogram (EEG) and magnetoencephalogram (MEG) methods. The interest for these methodologies relies in their high-temporal resolution as opposed to the investigation of such problem with the functional Magnetic Resonance Imaging (fMRI) methodology, also largely used in the marketing research. In addition, EEG and MEG technologies have greatly improved their spatial resolution in the last decades with the introduction of advanced signal processing methodologies. By presenting data gathered through MEG and high resolution EEG we will show which kind of information it is possible to gather with these methodologies while the persons are watching marketing relevant stimuli. Such information will be related to the memorization and pleasantness related to such stimuli. We noted that temporal and frequency patterns of brain signals are able to provide possible descriptors conveying information about the cognitive and emotional processes in subjects observing commercial advertisements. These information could be unobtainable through common tools used in standard marketing research. We also show an example of how an EEG methodology could be used to analyze cultural differences between fruition of video commercials of carbonated beverages in Western and Eastern countries.

  20. Implementing an International Consultation on Earth System Research Priorities Using Web 2.0 Tools

    Science.gov (United States)

    Goldfarb, L.; Yang, A.

    2009-12-01

    Leah Goldfarb, Paul Cutler, Andrew Yang*, Mustapha Mokrane, Jacinta Legg and Deliang Chen The scientific community has been engaged in developing an international strategy on Earth system research. The initial consultation in this “visioning” process focused on gathering suggestions for Earth system research priorities that are interdisciplinary and address the most pressing societal issues. It was implemented this through a website that utilized Web 2.0 capabilities. The website (http://www.icsu-visioning.org/) collected input from 15 July to 1 September 2009. This consultation was the first in which the international scientific community was asked to help shape the future of a research theme. The site attracted over 7000 visitors from 133 countries, more than 1000 of whom registered and took advantage of the site’s functionality to contribute research questions (~300 questions), comment on posts, and/or vote on questions. To facilitate analysis of results, the site captured a small set of voluntary information about each contributor and their contribution. A group of ~50 international experts were invited to analyze the inputs at a “Visioning Earth System Research” meeting held in September 2009. The outcome of this meeting—a prioritized list of research questions to be investigated over the next decade—was then posted on the visioning website for additional comment from the community through an online survey tool. In general, many lessons were learned in the development and implementation of this website, both in terms of the opportunities offered by Web 2.0 capabilities and the application of these capabilities. It is hoped that this process may serve as a model for other scientific communities. The International Council for Science (ICSU) in cooperation with the International Social Science Council (ISSC) is responsible for organizing this Earth system visioning process.

  1. Emerging role of bioinformatics tools and software in evolution of clinical research

    Directory of Open Access Journals (Sweden)

    Supreet Kaur Gill

    2016-01-01

    Full Text Available Clinical research is making toiling efforts for promotion and wellbeing of the health status of the people. There is a rapid increase in number and severity of diseases like cancer, hepatitis, HIV etc, resulting in high morbidity and mortality. Clinical research involves drug discovery and development whereas clinical trials are performed to establish safety and efficacy of drugs. Drug discovery is a long process starting with the target identification, validation and lead optimization. This is followed by the preclinical trials, intensive clinical trials and eventually post marketing vigilance for drug safety. Softwares and the bioinformatics tools play a great role not only in the drug discovery but also in drug development. It involves the use of informatics in the development of new knowledge pertaining to health and disease, data management during clinical trials and to use clinical data for secondary research. In addition, new technology likes molecular docking, molecular dynamics simulation, proteomics and quantitative structure activity relationship in clinical research results in faster and easier drug discovery process. During the preclinical trials, the software is used for randomization to remove bias and to plan study design. In clinical trials software like electronic data capture, Remote data capture and electronic case report form (eCRF is used to store the data. eClinical, Oracle clinical are software used for clinical data management and for statistical analysis of the data. After the drug is marketed the safety of a drug could be monitored by drug safety software like Oracle Argus or ARISg. Therefore, softwares are used from the very early stages of drug designing, to drug development, clinical trials and during pharmacovigilance. This review describes different aspects related to application of computers and bioinformatics in drug designing, discovery and development, formulation designing and clinical research.

  2. T cell uptake for the use of boron neutron capture as an immunologic research tool

    Energy Technology Data Exchange (ETDEWEB)

    Binello, E. E-mail: ebinello@mit.edu; Mitchell, R.N.; Harling, O.K

    2004-11-01

    An immunologic tool based on manipulation of the boron neutron capture reaction was previously proposed in the context of heart transplantation research to examine the temporal relationship between parenchymal rejection (representing immune cell infiltration) and transplantation-associated arteriosclerosis (characterized by progressive vascular occlusion). Critical to the development of this method is the uptake of boron by specific cells of the immune system, namely T cells, without adverse effects on cell function, which may be assessed by the ability of boron-loaded cells to produce IFN{gamma}, a protein with substantial impact on rejection. This work presents the evaluation of two carboranyl thymidine analogs. Advantages of this type of boron compound are reduced risk of leakage and effective dose delivery based on their incorporation into cellular nuclear material. Results indicate that uptake of these boronated nucleosides is high with no adverse effects on cell function, thereby warranting the continued development of this technique that has potentially wide applicability in immunological models.

  3. Consumption value theory and the marketing of public health: an effective formative research tool.

    Science.gov (United States)

    Nelson, Douglas G; Byus, Kent

    2002-01-01

    Contemporary public health requires the support and participation of its constituency. This study assesses the capacity of consumption value theory to identify the basis of this support. A telephone survey design used simple random sampling of adult residents of Cherokee County, Oklahoma. Factor analysis and stepwise discriminant analysis was used to identify and classify personal and societal level support variables. Most residents base societal level support on epistemic values. Direct services clientele base their support on positive emotional values derived from personal contact and attractive programs. Residents are curious about public health and want to know more about the health department. Where marketing the effectiveness of public health programs would yield relatively little support, marketing health promotion activities may attract public opposition. This formative research tool suggests a marketing strategy for public health practitioners.

  4. Public Interest Energy Research (PIER) Program Development of a Computer-based Benchmarking and Analytical Tool. Benchmarking and Energy & Water Savings Tool in Dairy Plants (BEST-Dairy)

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Tengfang [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Flapper, Joris [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Ke, Jing [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Kramer, Klaas [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Sathaye, Jayant [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2012-02-01

    The overall goal of the project is to develop a computer-based benchmarking and energy and water savings tool (BEST-Dairy) for use in the California dairy industry - including four dairy processes - cheese, fluid milk, butter, and milk powder. BEST-Dairy tool developed in this project provides three options for the user to benchmark each of the dairy product included in the tool, with each option differentiated based on specific detail level of process or plant, i.e., 1) plant level; 2) process-group level, and 3) process-step level. For each detail level, the tool accounts for differences in production and other variables affecting energy use in dairy processes. The dairy products include cheese, fluid milk, butter, milk powder, etc. The BEST-Dairy tool can be applied to a wide range of dairy facilities to provide energy and water savings estimates, which are based upon the comparisons with the best available reference cases that were established through reviewing information from international and national samples. We have performed and completed alpha- and beta-testing (field testing) of the BEST-Dairy tool, through which feedback from voluntary users in the U.S. dairy industry was gathered to validate and improve the tool's functionality. BEST-Dairy v1.2 was formally published in May 2011, and has been made available for free downloads from the internet (i.e., http://best-dairy.lbl.gov). A user's manual has been developed and published as the companion documentation for use with the BEST-Dairy tool. In addition, we also carried out technology transfer activities by engaging the dairy industry in the process of tool development and testing, including field testing, technical presentations, and technical assistance throughout the project. To date, users from more than ten countries in addition to those in the U.S. have downloaded the BEST-Dairy from the LBNL website. It is expected that the use of BEST-Dairy tool will advance understanding of energy and

  5. Authentication of animal origin of heparin and low molecular weight heparin including ovine, porcine and bovine species using 1D NMR spectroscopy and chemometric tools.

    Science.gov (United States)

    Monakhova, Yulia B; Diehl, Bernd W K; Fareed, Jawed

    2018-02-05

    High resolution (600MHz) nuclear magnetic resonance (NMR) spectroscopy is used to distinguish heparin and low-molecular weight heparins (LMWHs) produced from porcine, bovine and ovine mucosal tissues as well as their blends. For multivariate analysis several statistical methods such as principal component analysis (PCA), factor discriminant analysis (FDA), partial least squares - discriminant analysis (PLS-DA), linear discriminant analysis (LDA) were utilized for the modeling of NMR data of more than 100 authentic samples. Heparin and LMWH samples from the independent test set (n=15) were 100% correctly classified according to its animal origin. Moreover, by using 1 H NMR coupled with chemometrics and several batches of bovine heparins from two producers were differentiated. Thus, NMR spectroscopy combined with chemometrics is an efficient tool for simultaneous identification of animal origin and process based manufacturing difference in heparin products. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. The Right Tools for the Job: The Challenges of Theory and Method in Geoscience Education Research

    Science.gov (United States)

    Riggs, E. M.

    2011-12-01

    beginners. Thus researchers must embrace the uncontrolled nature of the setting, the qualitative nature of the data collected, and the researcher's role in interpreting geologically appropriate actions as evidence of successful problem solving and investigation. Working to understand the role of diversity and culture in the geosciences also involves a wide array of theory, from affective issues through culturally and linguistically-influenced cognition, through gender, self-efficacy, and many other areas of inquiry. Research in understanding spatial skills draws heavily on techniques from cognition research but also must involve the field-specific knowledge of geoscientists to infuse these techniques with exemplars, a catalog of meaningful actions by students, and an understanding of how to recognize success. These examples illustrate briefly the wide array of tools from other fields that is being brought to bear to advance rigorous geoscience education research. We will illustrate a few of these and the insights we have gained, and the power of theory and method from other fields to enlighten us as we attempt to educate a broader array of earth scientists.

  7. Auxiliary variables in multiple imputation in regression with missing X: a warning against including too many in small sample research

    Directory of Open Access Journals (Sweden)

    Hardt Jochen

    2012-12-01

    Full Text Available Abstract Background Multiple imputation is becoming increasingly popular. Theoretical considerations as well as simulation studies have shown that the inclusion of auxiliary variables is generally of benefit. Methods A simulation study of a linear regression with a response Y and two predictors X1 and X2 was performed on data with n = 50, 100 and 200 using complete cases or multiple imputation with 0, 10, 20, 40 and 80 auxiliary variables. Mechanisms of missingness were either 100% MCAR or 50% MAR + 50% MCAR. Auxiliary variables had low (r=.10 vs. moderate correlations (r=.50 with X’s and Y. Results The inclusion of auxiliary variables can improve a multiple imputation model. However, inclusion of too many variables leads to downward bias of regression coefficients and decreases precision. When the correlations are low, inclusion of auxiliary variables is not useful. Conclusion More research on auxiliary variables in multiple imputation should be performed. A preliminary rule of thumb could be that the ratio of variables to cases with complete data should not go below 1 : 3.

  8. Interpreting User's Choice of Technologies: A Quantitative Research on Choosing the Best Web-Based Communication Tools

    Science.gov (United States)

    Adebiaye, Richmond

    2010-01-01

    The proliferation of web-based communication tools like email clients vis-a-vis Yahoo mail, Gmail, and Hotmail have led to new innovations in web-based communication. Email users benefit greatly from this technology, but lack of security of these tools can put users at risk of loss of privacy, including identity theft, corporate espionage, and…

  9. Machine Assistance in Collection Building: New Tools, Research, Issues, and Reflections

    Directory of Open Access Journals (Sweden)

    Steve Mitchell

    2006-12-01

    Full Text Available Digital tool making offers many challenges, involving much trial and error. Developing machine learning and assistance in automated and semi-automated Internet resource discovery, metadata generation, and rich-text identification provides opportunities for great discovery, innovation, and the potential for transformation of the library community. The areas of computer science involved, as applied to the library applications addressed, are among that discipline’s leading edges. Making applied research practical and applicable, through placement within library/collection-management systems and services, involves equal parts computer scientist, research librarian, and legacy-systems archaeologist. Still, the early harvest is there for us now, with a large harvest pending. Data Fountains and iVia, the projects discussed, demonstrate this. Clearly, then, the present would be a good time for the library community to more proactively and significantly engage with this technology and research, to better plan for its impacts, to more proactively take up the challenges involved in its exploration, and to better and more comprehensively guide effort in this new territory. The alternative to doing this is that others will develop this territory for us, do it not as well, and sell it back to us at a premium. Awareness of this technology and its current capabilities, promises, limitations, and probable major impacts needs to be generalized throughout the library management, metadata, and systems communities. This article charts recent work, promising avenues for new research and development, and issues the library community needs to understand.

  10. Global cities rankings. A research agenda or a neoliberal urban planning tool?

    Directory of Open Access Journals (Sweden)

    Cándida Gago García

    2017-03-01

    Full Text Available This paper contains a theoretical reflection about the methodology and meaning given to the global city rankings. There is a very large academic production about the role that some cities have in global territorial processes, which has been related to the concept of global city. Many recent contributions from the mass media, advertising and consulting services must be considered also in the analysis. All of them have included new indicators in order to show the main role that cultural services have acquired in the urban economy. Also the city rankings are being used as a tool in neoliberal policies. These policies stress the position that cities have in the rankings, which are used in practices of city-branding and to justify the neoliberal decisions that are being taken. In fact, we think that rankings are used inappropriately and that it is necessary a deep and new reflection about them.

  11. Personal Health and Finance Quiz: A Tool for Outreach, Research, and Evaluation

    Directory of Open Access Journals (Sweden)

    Barbara O'Neill

    2015-02-01

    Full Text Available Rutgers Cooperative Extension developed an online self-assessment tool called the Personal Health and Finance Quiz available at http://njaes.rutgers.edu/money/health-finance-quiz/. Believed to be among the first public surveys to simultaneously query users about their health and personal finance practices, the quiz is part of Small Steps to Health and Wealth™ (SSHW, a Cooperative Extension program developed to motivate Americans to take action to improve both their health and personal finances (see http://njaes.rutgers.edu/sshw/. Respondents indicate one of four frequencies for performance of 20 daily activities and receive a Health, Finance, and Total score indicating their frequency of performing activities that health and financial experts recommend. In addition to providing users with personalized feedback, the quiz collects data for research about the health and financial practices of Americans to inform future Extension outreach and can be used as a pre-/post-test to evaluate the impact of SSHW programs. Initial research analyses are planned for 2015.

  12. An Information Literacy Course for Doctoral Students: Information Resources and Tools for Research

    Directory of Open Access Journals (Sweden)

    Ann-Louise Paasio

    2015-12-01

    Full Text Available The purpose of this paper is to showcase the information literacy course for doctoral students called Information Resources and Tools for Research. Turku University Library organises this course in collaboration with the University of Turku Graduate School. The course, which was started in 2012, has been organised four times so far, twice in English and twice in Finnish. The course offers training to all doctoral Programs in all of the seven disciplines present at the University of Turku and doctoral candidates of the University. In our presentation we will describe the structure and contents of the course and share our experiences of the collaboration with the University of Turku Graduate School. In addition, we will describe how the information specialists of the Turku University Library have collaborated during the course. We will also discuss the challenges of the course. Based on the course feedback, it can be stated that in general, participants have found this course very useful for their research in the University of Turku.

  13. Nanostructure of matrices for sulfur constructional composites: methodolody, methods and research tools

    Directory of Open Access Journals (Sweden)

    KOROLEV Evgenij Valerjevich

    2014-12-01

    Full Text Available Complex of operational properties of sulfur-based and sulfur-extended building materials may lead both to economical efficiency of construction and to reduced load on the environment. The feasibility of the sulfur-extended materials is primarily caused by properties, availability and low cost of sulfur. Before the development of building material it is necessary to examine the supramolecular structure of the matrix in detail. Material science of sulfur is still with several «white spots» which have to be filled with sound knowledge and reproducible data. New level of the research in constructional material science can be achieved with help of system analysis. The key prerequisite for successful application of system analysis in material science is the determination of primary interactions which, in turn, define applicable modeling methods. Several investigation methods can be used at the nanoscale level – traditional experimental methods, quantum chemistry modeling, molecular dynamics. The methodology of research depends on objectives and also on acceptable values of time and resource consumption. Requirements for precision and reproducibility, together with demands for new scientific data must also be taken into consideration. In the present work we have presented different strategies of investigation: case for dominance of practice, case for high demands for new scientific data and the case for high demands for precision, reliability and reproducibility. The latest case is the preferable one, and it was used during investigation of the nanostructure of sulfur binder. Three different methods of research were applied: Raman spectroscopy, quantum chemistry simulation and molecular dynamics. It was demonstrated again that broadly available technical sulfur corresponds to orthorhombic allotrope; at the same time, comparative analysis of the Raman spectra reveals that bending of long sulfur chains in technical sulfur takes place in less

  14. Ethical dimensions of psychiatric research: a constructive, criterion-based approach to protocol preparation. The Research Protocol Ethics Assessment Tool (RePEAT).

    Science.gov (United States)

    Roberts, L W

    1999-10-15

    Preparing experimental protocols that are ethically sound, possess scientific merit, and meet institutional and national standards for human subject protections is a key responsibility of psychiatric investigators. This task has become increasingly complex due to developments in biomedical science, bioethics, and society at large. Practical and constructive approaches to help investigators in their efforts to create protocols that are ethically acceptable have nevertheless received little attention. To better address this gap, the Research Protocol Ethics Assessment Tool (RePEAT) was developed as an educational instrument to help assure that ethically important elements, including scientific design features, are explicitly addressed by investigators in their work with protocols involving human participants. The RePEAT is a brief evaluative checklist that reflects rigorous ethical standards, particularly with respect to criteria for studies that may involve individuals with compromised decisional abilities. For this reason, it may be especially beneficial as a self-assessment tool for investigators and protocol reviewers in psychiatry. To stimulate education and dialogue, this report presents the RePEAT and outlines its content, format, use, and limitations.

  15. Photomat: A Mobile Tool for Aiding in Student Construction of Research Questions and Data Analysis

    Science.gov (United States)

    Shelley, Tia Renee; Dasgupta, Chandan; Silva, Alexandra; Lyons, Leilah; Moher, Tom

    2015-01-01

    This paper presents a new mobile software tool, PhotoMAT (Photo Management and Analysis Tool), and students' experiences with this tool within a scaffolded curricular unit--Neighborhood Safari. PhotoMAT was designed to support learners' investigations of backyard animal behavior and works with image sets obtained using fixed-position field cameras…

  16. Hydrothermal Microflow Technology as a Research Tool for Origin-of-Life Studies in Extreme Earth Environments.

    Science.gov (United States)

    Kawamura, Kunio

    2017-10-02

    Although studies about the origin of life are a frontier in science and a number of effective approaches have been developed, drawbacks still exist. Examples include: (1) simulation of chemical evolution experiments (which were demonstrated for the first time by Stanley Miller); (2) approaches tracing back the most primitive life-like systems (on the basis of investigations of present organisms); and (3) constructive approaches for making life-like systems (on the basis of molecular biology), such as in vitro construction of the RNA world. Naturally, simulation experiments of chemical evolution under plausible ancient Earth environments have been recognized as a potentially fruitful approach. Nevertheless, simulation experiments seem not to be sufficient for identifying the scenario from molecules to life. This is because primitive Earth environments are still not clearly defined and a number of possibilities should be taken into account. In addition, such environments frequently comprise extreme conditions when compared to the environments of present organisms. Therefore, we need to realize the importance of accurate and convenient experimental approaches that use practical research tools, which are resistant to high temperature and pressure, to facilitate chemical evolution studies. This review summarizes improvements made in such experimental approaches over the last two decades, focusing primarily on our hydrothermal microflow reactor technology. Microflow reactor systems are a powerful tool for performing simulation experiments in diverse simulated hydrothermal Earth conditions in order to measure the kinetics of formation and degradation and the interactions of biopolymers.

  17. Innovative Near Real-Time Data Dissemination Tools Developed by the Space Weather Research Center

    Science.gov (United States)

    Mullinix, R.; Maddox, M. M.; Berrios, D.; Kuznetsova, M.; Pulkkinen, A.; Rastaetter, L.; Zheng, Y.

    2012-12-01

    Space weather affects virtually all of NASA's endeavors, from robotic missions to human exploration. Knowledge and prediction of space weather conditions are therefore essential to NASA operations. The diverse nature of currently available space environment measurements and modeling products compels the need for a single access point to such information. The Integrated Space Weather Analysis (iSWA) System provides this single point access along with the capability to collect and catalog a vast range of sources including both observational and model data. NASA Goddard Space Weather Research Center heavily utilizes the iSWA System daily for research, space weather model validation, and forecasting for NASA missions. iSWA provides the capabilities to view and analyze near real-time space weather data from any where in the world. This presentation will describe the technology behind the iSWA system and describe how to use the system for space weather research, forecasting, training, education, and sharing.

  18. Star wars: space-age laser weapons show potential as drilling tools in new U.S. research program

    Energy Technology Data Exchange (ETDEWEB)

    Harvie, W.

    1998-08-03

    Research into the use of lasers, developed under the U.S. star wars strategic defence program, for drilling oil and gas wells is being reported. Although still in the conceptual stage, laboratory research suggests that if penetration rates achieved in the laboratory could be duplicated under field conditions, drilling speeds could be increased 100-fold. The trick appears to be making the laser broad enough in diameter to allow the insertion of testing, stimulation and other tools into the bore. The chemical oxygen-iodine laser (COIL), invented in 1977 to track and destroy missiles, which also works with fibre optic tubing, appears to be well suited for power projection over long distances, such as oil-well drilling. Another variety of laser, the mid-infrared advanced chemical laser (MIRACL), first developed in 1980 as a shipboard defence system, also has the demonstrated power to burn through solid materials such as `soft rock`. At least two other laser types, the electric discharge coaxial laser I, and the laser device demonstration have been tested extensively, and are considered to have suitable operating characteristics. A modest two-year research program is currently underway at the Colorado School of Mines. Many U.S. firms, including some drilling companies, have expressed interest in providing funding to continue the project. The final bill might be as high as $ 50 to 100 million before a field version becomes available.

  19. 76 FR 47216 - Expediting Research Tools to NIH Licensees Through the Use of Pay.gov for Rapid Processing of...

    Science.gov (United States)

    2011-08-04

    ... licensed from the NIH and FDA intramural research programs. The value of such time savings to corporate R&D... bank-to-bank transfer system at Pay.gov has shortened the processing time for research tool and other... me about 5 minutes after reading the email/letter to process payment. Great service!'' and ``I just...

  20. Assessment of the structural and functional impact of in-frame mutations of the DMD gene, using the tools included in the eDystrophin online database.

    Science.gov (United States)

    Nicolas, Aurélie; Lucchetti-Miganeh, Céline; Yaou, Rabah Ben; Kaplan, Jean-Claude; Chelly, Jamel; Leturcq, France; Barloy-Hubler, Frédérique; Le Rumeur, Elisabeth

    2012-07-09

    Dystrophin is a large essential protein of skeletal and heart muscle. It is a filamentous scaffolding protein with numerous binding domains. Mutations in the DMD gene, which encodes dystrophin, mostly result in the deletion of one or several exons and cause Duchenne (DMD) and Becker (BMD) muscular dystrophies. The most common DMD mutations are frameshift mutations resulting in an absence of dystrophin from tissues. In-frame DMD mutations are less frequent and result in a protein with partial wild-type dystrophin function. The aim of this study was to highlight structural and functional modifications of dystrophin caused by in-frame mutations. We developed a dedicated database for dystrophin, the eDystrophin database. It contains 209 different non frame-shifting mutations found in 945 patients from a French cohort and previous studies. Bioinformatics tools provide models of the three-dimensional structure of the protein at deletion sites, making it possible to determine whether the mutated protein retains the typical filamentous structure of dystrophin. An analysis of the structure of mutated dystrophin molecules showed that hybrid repeats were reconstituted at the deletion site in some cases. These hybrid repeats harbored the typical triple coiled-coil structure of native repeats, which may be correlated with better function in muscle cells. This new database focuses on the dystrophin protein and its modification due to in-frame deletions in BMD patients. The observation of hybrid repeat reconstitution in some cases provides insight into phenotype-genotype correlations in dystrophin diseases and possible strategies for gene therapy. The eDystrophin database is freely available: http://edystrophin.genouest.org/.

  1. Moroccan TRIGA nuclear reactor, an important tool for the development of research, education and training

    International Nuclear Information System (INIS)

    Caoui, A.

    2011-01-01

    Full text: The construction of the Nuclear Research Center of Maamora (NRCM) will enable to the National Center for Nuclear Energy, Sciences and Techniques (CNESTEN) to fulfill its missions for promotion of nuclear techniques in socioeconomic fields, act as technical support for the authorities, and contribute to the introduction of nuclear power for electricity generation considered in the new energy strategy as alternative option for the period 2020-2030. The CNESTEN has commisioned its nuclear research reactor Triga Mark II of 2000 KW on 2007 for wich the operating authorization was delivered on 2009. This research reactor is the keystone structure of the NRCM, its existing and planed utilization include: production of radioisotopes for medical use, neutron activation analysis, non-destructive examination techniques, neutron scattering, reactor physics research and training. In term of human ressources development, CNESTEN is more focusing on education and training for wich an international training Center is under development. The TRIGA research reactor will be an important component of this center. In order to promote the utilization of the reserch reactor in socio-economical sectors at national level, CNESTEN organizea meetings, schools and conferences around each of the reactor applications, and offers the opportunity to researchers, students, socio-economic operators to know more about reactor utilization within scientific visits, courses and training programs. At the international level, CNESTEN strengthens its international partenership. The regional and international cooperation with IAEA, AFRA and bilateral parteners (USA, France), constitutes the platform for capacity building in different areas of CNESTEN RIGA research reactor utilization

  2. A web-based tool to engage stakeholders in informing research planning for future decisions on emerging materials

    International Nuclear Information System (INIS)

    Powers, Christina M.; Grieger, Khara D.; Hendren, Christine Ogilvie; Meacham, Connie A.; Gurevich, Gerald; Lassiter, Meredith Gooding; Money, Eric S.; Lloyd, Jennifer M.; Beaulieu, Stephen M.

    2014-01-01

    Prioritizing and assessing risks associated with chemicals, industrial materials, or emerging technologies is a complex problem that benefits from the involvement of multiple stakeholder groups. For example, in the case of engineered nanomaterials (ENMs), scientific uncertainties exist that hamper environmental, health, and safety (EHS) assessments. Therefore, alternative approaches to standard EHS assessment methods have gained increased attention. The objective of this paper is to describe the application of a web-based, interactive decision support tool developed by the U.S. Environmental Protection Agency (U.S. EPA) in a pilot study on ENMs. The piloted tool implements U.S. EPA's comprehensive environmental assessment (CEA) approach to prioritize research gaps. When pursued, such research priorities can result in data that subsequently improve the scientific robustness of risk assessments and inform future risk management decisions. Pilot results suggest that the tool was useful in facilitating multi-stakeholder prioritization of research gaps. Results also provide potential improvements for subsequent applications. The outcomes of future CEAWeb applications with larger stakeholder groups may inform the development of funding opportunities for emerging materials across the scientific community (e.g., National Science Foundation Science to Achieve Results [STAR] grants, National Institutes of Health Requests for Proposals). - Highlights: • A web-based, interactive decision support tool was piloted for emerging materials. • The tool (CEAWeb) was based on an established approach to prioritize research gaps. • CEAWeb facilitates multi-stakeholder prioritization of research gaps. • We provide recommendations for future versions and applications of CEAWeb

  3. Research standardization tools: pregnancy measures in the PhenX Toolkit.

    Science.gov (United States)

    Malinowski, Ann Kinga; Ananth, Cande V; Catalano, Patrick; Hines, Erin P; Kirby, Russell S; Klebanoff, Mark A; Mulvihill, John J; Simhan, Hyagriv; Hamilton, Carol M; Hendershot, Tabitha P; Phillips, Michael J; Kilpatrick, Lisa A; Maiese, Deborah R; Ramos, Erin M; Wright, Rosalind J; Dolan, Siobhan M

    2017-09-01

    Only through concerted and well-executed research endeavors can we gain the requisite knowledge to advance pregnancy care and have a positive impact on maternal and newborn health. Yet the heterogeneity inherent in individual studies limits our ability to compare and synthesize study results, thus impeding the capacity to draw meaningful conclusions that can be trusted to inform clinical care. The PhenX Toolkit (http://www.phenxtoolkit.org), supported since 2007 by the National Institutes of Health, is a web-based catalog of standardized protocols for measuring phenotypes and exposures relevant for clinical research. In 2016, a working group of pregnancy experts recommended 15 measures for the PhenX Toolkit that are highly relevant to pregnancy research. The working group followed the established PhenX consensus process to recommend protocols that are broadly validated, well established, nonproprietary, and have a relatively low burden for investigators and participants. The working group considered input from the pregnancy experts and the broader research community and included measures addressing the mode of conception, gestational age, fetal growth assessment, prenatal care, the mode of delivery, gestational diabetes, behavioral and mental health, and environmental exposure biomarkers. These pregnancy measures complement the existing measures for other established domains in the PhenX Toolkit, including reproductive health, anthropometrics, demographic characteristics, and alcohol, tobacco, and other substances. The preceding domains influence a woman's health during pregnancy. For each measure, the PhenX Toolkit includes data dictionaries and data collection worksheets that facilitate incorporation of the protocol into new or existing studies. The measures within the pregnancy domain offer a valuable resource to investigators and clinicians and are well poised to facilitate collaborative pregnancy research with the goal to improve patient care. To achieve this

  4. Assessing the impact of user-centered research on a clinical trial eHealth tool via counterbalanced research design.

    Science.gov (United States)

    Atkinson, Nancy L; Massett, Holly A; Mylks, Christy; McCormack, Lauren A; Kish-Doto, Julia; Hesse, Bradford W; Wang, Min Qi

    2011-01-01

    Informatics applications have the potential to improve participation in clinical trials, but their design must be based on user-centered research. This research used a fully counterbalanced experimental design to investigate the effect of changes made to the original version of a website, http://BreastCancerTrials.org/, and confirm that the revised version addressed and reinforced patients' needs and expectations. Participants included women who had received a breast cancer diagnosis within the last 5 years (N=77). They were randomized into two groups: one group used and reviewed the original version first followed by the redesigned version, and the other group used and reviewed them in reverse order. The study used both quantitative and qualitative measures. During use, participants' click paths and general reactions were observed. After use, participants were asked to answer survey items and open-ended questions to indicate their reactions and which version they preferred and met their needs and expectations better. Overall, the revised version of the site was preferred and perceived to be clearer, easier to navigate, more trustworthy and credible, and more private and safe overall. However, users who viewed the original version last had similar attitudes toward both versions. By applying research findings to the redesign of a website for clinical trial searching, it was possible to re-engineer the interface to better support patients' decisions to participate in clinical trials. The mechanisms of action in this case appeared to revolve around creating an environment that supported a sense of personal control and decisional autonomy.

  5. Electric Field Encephalography as a tool for functional brain research: a modeling study.

    Directory of Open Access Journals (Sweden)

    Yury Petrov

    Full Text Available We introduce the notion of Electric Field Encephalography (EFEG based on measuring electric fields of the brain and demonstrate, using computer modeling, that given the appropriate electric field sensors this technique may have significant advantages over the current EEG technique. Unlike EEG, EFEG can be used to measure brain activity in a contactless and reference-free manner at significant distances from the head surface. Principal component analysis using simulated cortical sources demonstrated that electric field sensors positioned 3 cm away from the scalp and characterized by the same signal-to-noise ratio as EEG sensors provided the same number of uncorrelated signals as scalp EEG. When positioned on the scalp, EFEG sensors provided 2-3 times more uncorrelated signals. This significant increase in the number of uncorrelated signals can be used for more accurate assessment of brain states for non-invasive brain-computer interfaces and neurofeedback applications. It also may lead to major improvements in source localization precision. Source localization simulations for the spherical and Boundary Element Method (BEM head models demonstrated that the localization errors are reduced two-fold when using electric fields instead of electric potentials. We have identified several techniques that could be adapted for the measurement of the electric field vector required for EFEG and anticipate that this study will stimulate new experimental approaches to utilize this new tool for functional brain research.

  6. Unraveling the web of viroinformatics: computational tools and databases in virus research.

    Science.gov (United States)

    Sharma, Deepak; Priyadarshini, Pragya; Vrati, Sudhanshu

    2015-02-01

    The beginning of the second century of research in the field of virology (the first virus was discovered in 1898) was marked by its amalgamation with bioinformatics, resulting in the birth of a new domain--viroinformatics. The availability of more than 100 Web servers and databases embracing all or specific viruses (for example, dengue virus, influenza virus, hepatitis virus, human immunodeficiency virus [HIV], hemorrhagic fever virus [HFV], human papillomavirus [HPV], West Nile virus, etc.) as well as distinct applications (comparative/diversity analysis, viral recombination, small interfering RNA [siRNA]/short hairpin RNA [shRNA]/microRNA [miRNA] studies, RNA folding, protein-protein interaction, structural analysis, and phylotyping and genotyping) will definitely aid the development of effective drugs and vaccines. However, information about their access and utility is not available at any single source or on any single platform. Therefore, a compendium of various computational tools and resources dedicated specifically to virology is presented in this article. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  7. The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories.

    Science.gov (United States)

    Weber, Griffin M; Murphy, Shawn N; McMurry, Andrew J; Macfadden, Douglas; Nigrin, Daniel J; Churchill, Susanne; Kohane, Isaac S

    2009-01-01

    The authors developed a prototype Shared Health Research Information Network (SHRINE) to identify the technical, regulatory, and political challenges of creating a federated query tool for clinical data repositories. Separate Institutional Review Boards (IRBs) at Harvard's three largest affiliated health centers approved use of their data, and the Harvard Medical School IRB approved building a Query Aggregator Interface that can simultaneously send queries to each hospital and display aggregate counts of the number of matching patients. Our experience creating three local repositories using the open source Informatics for Integrating Biology and the Bedside (i2b2) platform can be used as a road map for other institutions. The authors are actively working with the IRBs and regulatory groups to develop procedures that will ultimately allow investigators to obtain identified patient data and biomaterials through SHRINE. This will guide us in creating a future technical architecture that is scalable to a national level, compliant with ethical guidelines, and protective of the interests of the participating hospitals.

  8. Neutron tomography of particulate filters: a non-destructive investigation tool for applied and industrial research

    Science.gov (United States)

    Toops, Todd J.; Bilheux, Hassina Z.; Voisin, Sophie; Gregor, Jens; Walker, Lakeisha; Strzelec, Andrea; Finney, Charles E. A.; Pihl, Josh A.

    2013-11-01

    This research describes the development and implementation of high-fidelity neutron imaging and the associated analysis of the images. This advanced capability allows the non-destructive, non-invasive imaging of particulate filters (PFs) and how the deposition of particulate and catalytic washcoat occurs within the filter. The majority of the efforts described here were performed at the High Flux Isotope Reactor (HFIR) CG-1D neutron imaging beamline at Oak Ridge National Laboratory; the current spatial resolution is approximately 50 μm. The sample holder is equipped with a high-precision rotation stage that allows 3D imaging (i.e., computed tomography) of the sample when combined with computerized reconstruction tools. What enables the neutron-based image is the ability of some elements to absorb or scatter neutrons where other elements allow the neutron to pass through them with negligible interaction. Of particular interest in this study is the scattering of neutrons by hydrogen-containing molecules, such as hydrocarbons (HCs) and/or water, which are adsorbed to the surface of soot, ash and catalytic washcoat. Even so, the interactions with this adsorbed water/HC is low and computational techniques were required to enhance the contrast, primarily a modified simultaneous iterative reconstruction technique (SIRT). This effort describes the following systems: particulate randomly distributed in a PF, ash deposition in PFs, a catalyzed washcoat layer in a PF, and three particulate loadings in a SiC PF.

  9. Hyperacusis Questionnaire as a Tool for Measuring Hypersensitivity to Sound in a Tinnitus Research Population

    Directory of Open Access Journals (Sweden)

    Kathryn Fackrell

    2015-01-01

    Full Text Available Hypersensitivity to external sounds is often comorbid with tinnitus and may be significant for adherence to certain types of tinnitus management. Therefore, a clear measure of sensitivity to sound is important. The aim of this study was to evaluate the validity and reliability of the Hyperacusis Questionnaire (HQ for use as a measurement tool using data from a sample of 264 adults who took part in tinnitus research. We evaluated the HQ factor structure, internal consistency, convergent and discriminant validity, and floor and ceiling effects. Internal consistency was high (Cronbach’s alpha = 0.88 and moderate correlations were observed between the HQ, uncomfortable loudness levels, and other health questionnaires. Confirmatory factor analysis revealed that the original HQ three-factor solution and a one-factor solution were both a poor fit to the data. Four problematic items were removed and exploratory factor analysis identified a two-factor (attentional and social solution. The original three-factor structure of the HQ was not confirmed. All fourteen items do not accurately assess hypersensitivity to sound in a tinnitus population. We propose a 10-item (2-factor version of the HQ, which will need to be confirmed using a new tinnitus and perhaps nontinnitus population.

  10. Hyperacusis Questionnaire as a Tool for Measuring Hypersensitivity to Sound in a Tinnitus Research Population.

    Science.gov (United States)

    Fackrell, Kathryn; Fearnley, Constance; Hoare, Derek J; Sereda, Magdalena

    2015-01-01

    Hypersensitivity to external sounds is often comorbid with tinnitus and may be significant for adherence to certain types of tinnitus management. Therefore, a clear measure of sensitivity to sound is important. The aim of this study was to evaluate the validity and reliability of the Hyperacusis Questionnaire (HQ) for use as a measurement tool using data from a sample of 264 adults who took part in tinnitus research. We evaluated the HQ factor structure, internal consistency, convergent and discriminant validity, and floor and ceiling effects. Internal consistency was high (Cronbach's alpha = 0.88) and moderate correlations were observed between the HQ, uncomfortable loudness levels, and other health questionnaires. Confirmatory factor analysis revealed that the original HQ three-factor solution and a one-factor solution were both a poor fit to the data. Four problematic items were removed and exploratory factor analysis identified a two-factor (attentional and social) solution. The original three-factor structure of the HQ was not confirmed. All fourteen items do not accurately assess hypersensitivity to sound in a tinnitus population. We propose a 10-item (2-factor) version of the HQ, which will need to be confirmed using a new tinnitus and perhaps nontinnitus population.

  11. Electron Tomography: A Three-Dimensional Analytic Tool for Hard and Soft Materials Research.

    Science.gov (United States)

    Ercius, Peter; Alaidi, Osama; Rames, Matthew J; Ren, Gang

    2015-10-14

    Three-dimensional (3D) structural analysis is essential to understand the relationship between the structure and function of an object. Many analytical techniques, such as X-ray diffraction, neutron spectroscopy, and electron microscopy imaging, are used to provide structural information. Transmission electron microscopy (TEM), one of the most popular analytic tools, has been widely used for structural analysis in both physical and biological sciences for many decades, in which 3D objects are projected into two-dimensional (2D) images. In many cases, 2D-projection images are insufficient to understand the relationship between the 3D structure and the function of nanoscale objects. Electron tomography (ET) is a technique that retrieves 3D structural information from a tilt series of 2D projections, and is gradually becoming a mature technology with sub-nanometer resolution. Distinct methods to overcome sample-based limitations have been separately developed in both physical and biological science, although they share some basic concepts of ET. This review discusses the common basis for 3D characterization, and specifies difficulties and solutions regarding both hard and soft materials research. It is hoped that novel solutions based on current state-of-the-art techniques for advanced applications in hybrid matter systems can be motivated. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. DART: Tools and Support for Ensemble Data Assimilation Research, Operations, and Education

    Science.gov (United States)

    Anderson, J. L.; Raeder, K.; Hoar, T. J.; Collins, N.; Kershaw, H.; Romine, G. S.; Liu, H.; Mizzi, A. P.; Lei, L.; Chatterjee, A.; Karspeck, A. R.; Pedatella, N. M.

    2013-12-01

    presented. The poster includes instructions on how to get started using DART for research or educational applications.

  13. A tool for integrating genetic and mass spectrometry-based peptide data: Proteogenomics Viewer: PV: A genome browser-like tool, which includes MS data visualization and peptide identification parameters.

    Science.gov (United States)

    Kroll, José Eduardo; da Silva, Vandeclécio Lira; de Souza, Sandro José; de Souza, Gustavo Antonio

    2017-07-01

    In this manuscript we describe Proteogenomics Viewer, a web-based tool that collects MS peptide identification, indexes to genomic sequence and structure, assigns exon usage, reports the identified protein isoforms with genomic alignments and, most importantly, allows the inspection of MS2 information for proper peptide identification. It also provides all performed indexing to facilitate global analysis of the data. The relevance of such tool is that there has been an increase in the number of proteogenomic efforts to improve the annotation of both genomics and proteomics data, culminating with the release of the two human proteome drafts. It is now clear that mass spectrometry-based peptide identification of uncharacterized sequences, such as those resulting from unpredicted exon joints or non-coding regions, is still prone to a higher than expected false discovery rate. Therefore, proper visualization of the raw data and the corresponding genome alignments are fundamental for further data validation and interpretation. Also see the video abstract here: http://youtu.be/5NzyRvuk4Ac. © 2017 WILEY Periodicals, Inc.

  14. The use of content marketing strategy tools in the Polish research institutes

    Directory of Open Access Journals (Sweden)

    Świeczak Witold

    2016-12-01

    Full Text Available In the article were described issues associated with the use by scientific institutions content marketing strategy tools. This article shows the extent to which tools of modern marketing are used in the Internet communication by scientific institutions. Currently content marketing concept is accepted not only as a fashionable trend of modern marketing but above all, it is treated as an important tool to improve enough Internet message, to effectively interest to the users. A optimal selection and use content marketing tools it provides opportunities for enhancing efficiency in the reception (acceptance of the generated message.

  15. Single particle ICP-MS as a tool for determining the stability of silver nanoparticles in aquatic matrixes under various environmental conditions, including treatment by ozonation.

    Science.gov (United States)

    Telgmann, Lena; Nguyen, Michael Thanh Khoa; Shen, Li; Yargeau, Viviane; Hintelmann, Holger; Metcalfe, Chris D

    2016-07-01

    Silver nanoparticles (AgNPs) are used in a large number of consumer products due to their antimicrobial and antifungal properties, and these materials may be discharged into municipal wastewater. Wastewater treatment, including advanced oxidation processes (AOPs), may modify the forms of silver in wastewater before they are discharged into surface waters. In addition, little is known about the changes in AgNPs that occur in natural waters under different environmental conditions. In this project, we utilized single particle ICP-MS (spICP-MS) and dynamic light scattering (DLS) analytical techniques to evaluate changes in the number and size of AgNPs in laboratory experiments with milliQ water under different environmental conditions, as well as during ozonation. Changes in the number and size of AgNPs determined by spICP-MS were evidence of altered stability of the nanoparticles. Increased rates of dissolution occurred under extremes of pH. Lower temperature decreased the rate of dissolution of AgNP relative to the dissolution in treatments at room temperature. The addition of chloride resulted in the loss of AgNPs from suspension due to agglomeration and precipitation. Ozonation led to a rapid decline in the number and size of AgNPs, as indicated by both spICP-MS and DLS analysis. An increase in the concentration of dissolved silver in the ozone treatments was evidence that changes in particle size were a result of oxidative dissolution of AgNPs to silver ion. Graphical abstract Single particle ICP-MS is used to evaluate dissolution of silver nanoparticles under different environmental conditions, including water treatment by ozonation.

  16. ERTS-A data as a teaching and research tool in the Department of Geology

    Science.gov (United States)

    Grybeck, D. (Principal Investigator)

    1974-01-01

    The author has identified the following significant results. The project was an attempt to integrate ERTS-1 data into teaching introductory, specialized, and graduate courses in the Department of Geology, University of Alaska. This data was to be utilized principally through a specially selected, high quality collection of black and white, and color 9.5 mosaics of the State of Alaska. In completing these tasks, the data accumulated has proved highly useful in a variety of ways including: (1) discussions of the uses and availability of ERTS imagery; (2) as a medium for talking about and showing various areas of Alaska; (3) in discussing geology in general; and (4) as an aid in doing research and as possible research topics themselves. Use of ERTS-1 imagery in geology proved highly successful and its use is now an integral part of many courses.

  17. Scholarship 2.0: analyzing scholars’ use of Web 2.0 tools in research and teaching activity

    Directory of Open Access Journals (Sweden)

    Licia Calvi

    2013-11-01

    Full Text Available Over the past 15 years the Web has transformed the ways in which we search for information and use it. In more recent years, we have seen the emergence of a new array of innovative tools that collectively go under the name of ‘Web 2.0’, in which the information user is also increasingly an information producer (i.e., prosumer, by sharing or creating content.The success of Web 2.0 tools for personal use is only partially replicated in the professional sphere and, particularly, in the academic environment in relation with research and teaching.To date, very few studies have explored the level of adoption of Web 2.0 among academic researchers in their research and teaching activity. It is not known in what way how and how much Web 2.0 is currently used within research communities, and we are not aware of the drivers and the drawbacks of the use of Web 2.0 tools in academia, where the majority of people is focused either on research or on teaching activities.To analyse these issues, i.e. the combined adoption of Web 2.0 tools in teaching and research, the authors carried out a survey among teaching and researching staff of the University of Breda in The Netherlands. This country was chosen mainly because it is on the cutting edge as far as innovation is concerned. An important driver in choosing the Breda University’s academic community was the fact that one of the two authors of this survey works as senior researcher at this university.The purpose of our survey was to explore the level of adoption of Web 2.0 tools among the academic communities. We were interested in investigating how they were using these tools in the creation of scientific knowledge both in their research and teaching activity. We were also interested in analysing differences in the level of adoption of Web 2.0 tools with regard to researchers’ position, age, gender, and research field.Finally, in our study we explored the issue of peer reviewing in the Web 2.0 setting

  18. Using the open Web as an information resource and scholarly Web search engines as retrieval tools for academic and research purposes

    OpenAIRE

    Filistea Naude; Chris Rensleigh; Adeline S.A. du Toit

    2010-01-01

    This study provided insight into the significance of the open Web as an information resource and Web search engines as research tools amongst academics. The academic staff establishment of the University of South Africa (Unisa) was invited to participate in a questionnaire survey and included 1188 staff members from five colleges. This study culminated in a PhD dissertation in 2008. One hundred and eighty seven respondents participated in the survey which gave a response rate of 15.7%. The re...

  19. Using a web-based survey tool to undertake a Delphi study: application for nurse education research.

    Science.gov (United States)

    Gill, Fenella J; Leslie, Gavin D; Grech, Carol; Latour, Jos M

    2013-11-01

    The Internet is increasingly being used as a data collection medium to access research participants. This paper reports on the experience and value of using web-survey software to conduct an eDelphi study to develop Australian critical care course graduate practice standards. The eDelphi technique used involved the iterative process of administering three rounds of surveys to a national expert panel. The survey was developed online using SurveyMonkey. Panel members responded to statements using one rating scale for round one and two scales for rounds two and three. Text boxes for panel comments were provided. For each round, the SurveyMonkey's email tool was used to distribute an individualized email invitation containing the survey web link. The distribution of panel responses, individual responses and a summary of comments were emailed to panel members. Stacked bar charts representing the distribution of responses were generated using the SurveyMonkey software. Panel response rates remained greater than 85% over all rounds. An online survey provided numerous advantages over traditional survey approaches including high quality data collection, ease and speed of survey administration, direct communication with the panel and rapid collation of feedback allowing data collection to be undertaken in 12 weeks. Only minor challenges were experienced using the technology. Ethical issues, specific to using the Internet to conduct research and external hosting of web-based software, lacked formal guidance. High response rates and an increased level of data quality were achieved in this study using web-survey software and the process was efficient and user-friendly. However, when considering online survey software, it is important to match the research design with the computer capabilities of participants and recognize that ethical review guidelines and processes have not yet kept pace with online research practices. Copyright © 2013 Elsevier Ltd. All rights reserved.

  20. Low-rank coal research. Final technical report, April 1, 1988--June 30, 1989, including quarterly report, April--June 1989

    Energy Technology Data Exchange (ETDEWEB)

    1989-12-31

    This work is a compilation of reports on ongoing research at the University of North Dakota. Topics include: Control Technology and Coal Preparation Research (SO{sub x}/NO{sub x} control, waste management), Advanced Research and Technology Development (turbine combustion phenomena, combustion inorganic transformation, coal/char reactivity, liquefaction reactivity of low-rank coals, gasification ash and slag characterization, fine particulate emissions), Combustion Research (fluidized bed combustion, beneficiation of low-rank coals, combustion characterization of low-rank coal fuels, diesel utilization of low-rank coals), Liquefaction Research (low-rank coal direct liquefaction), and Gasification Research (hydrogen production from low-rank coals, advanced wastewater treatment, mild gasification, color and residual COD removal from Synfuel wastewaters, Great Plains Gasification Plant, gasifier optimization).

  1. Non-powered hand tool improvement research for prevention of work-related problems: a review.

    Science.gov (United States)

    Jain, Rahul; Sain, Manoj Kumar; Meena, Makkhan Lal; Dangayach, Govind Sharan; Bhardwaj, Awadhesh Kumar

    2017-03-28

    In lower-middle-income countries, most of the work is performed manually using non-ergonomic hand tools which results in work-related health problems. Using hand tools designed in line with ergonomic principles may play an important role in reducing work-related health concerns significantly. Scientific databases (PubMed, EBSCOhost) and e-publishers were searched for articles from 1985 to 2015 using the following keywords: 'hand tool', 'ergonomics', 'usability' and 'design'. After applying selection criteria to 614 articles, 58 articles related to the physical design of hand tools were selected. Seventeen articles were related to hand tool improvement in the manufacturing sector. Musculoskeletal disorders were found to be the most frequently occurring work-related health problems. Most of the articles focused on product and qualitative variables for improvement in hand tools, while few articles considered human and task variables. Literature shows that hand tool improvement studies have been given less importance in low-income and lower-middle-income countries. However, some work of significance is reported in the agriculture sectors of these countries. Hence, it is concluded that ergonomic intervention in hand tools is much needed for those industries which employ traditional methods of working.

  2. A decision-making tool for incorporating sustainability measures into pavement design : research project capsule.

    Science.gov (United States)

    2016-10-01

    The objective of the proposed study is to conceive and develop a decision-making tool : for evaluating sustainability of pavement designs based on a cradle-to-grave analysis. : This tool will utilize EPDs to enhance the reliability of the assessment ...

  3. RD and D-Programme 2004. Programme for research, development and demonstration of methods for the management and disposal of nuclear waste, including social science research

    International Nuclear Information System (INIS)

    2004-09-01

    SKB (the Swedish Nuclear Fuel and Waste Management Co), which is owned by the companies that operate the Swedish nuclear power plants, has been assigned the task of managing and disposing of the spent nuclear fuel from the reactors. The Nuclear Activities Act requires a programme of comprehensive research and development and other measures that are needed to manage and dispose of nuclear waste in a safe manner and to decommission and dismantle the nuclear power plants. SKB is now presenting RD and D-Programme 2004 in fulfilment of this requirement. The programme describes SKB's plans for the period 2005-2010. The period of immediate concern is 2005-2007. The level of detail for the three subsequent years is naturally lower.The programme provides a basis for designing systems for safe management and disposal of the radioactive waste from the nuclear power plants. SKB's plan is to implement deep disposal of the spent fuel in accordance with the KBS-3 method. In the RD and D-Programme we describe our activities and planning for this line of action and the work that is being conducted on alternative methods. Review of the programme can contribute valuable outside viewpoints. The regulatory authorities and the Government can clarify how they look upon different parts of the programme and stipulate guidelines for the future. Municipalities and other stakeholders can, after studying the programme, offer their viewpoints to SKB, the regulatory authorities or the Government.The goal for the period up to the end of 2008 is to be able to submit permit applications for the encapsulation plant and the deep repository. This RD and D-Programme therefore differs from the preceding ones in that it concentrates on questions relating to technology development for these facilities. The programmes for safety assessment and research on the long-term processes that take place in the deep repository are then linked together with the programmes for technology development. Another new

  4. RD and D-Programme 2004. Programme for research, development and demonstration of methods for the management and disposal of nuclear waste, including social science research

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-09-01

    SKB (the Swedish Nuclear Fuel and Waste Management Co), which is owned by the companies that operate the Swedish nuclear power plants, has been assigned the task of managing and disposing of the spent nuclear fuel from the reactors. The Nuclear Activities Act requires a programme of comprehensive research and development and other measures that are needed to manage and dispose of nuclear waste in a safe manner and to decommission and dismantle the nuclear power plants. SKB is now presenting RD and D-Programme 2004 in fulfilment of this requirement. The programme describes SKB's plans for the period 2005-2010. The period of immediate concern is 2005-2007. The level of detail for the three subsequent years is naturally lower.The programme provides a basis for designing systems for safe management and disposal of the radioactive waste from the nuclear power plants. SKB's plan is to implement deep disposal of the spent fuel in accordance with the KBS-3 method. In the RD and D-Programme we describe our activities and planning for this line of action and the work that is being conducted on alternative methods. Review of the programme can contribute valuable outside viewpoints. The regulatory authorities and the Government can clarify how they look upon different parts of the programme and stipulate guidelines for the future. Municipalities and other stakeholders can, after studying the programme, offer their viewpoints to SKB, the regulatory authorities or the Government.The goal for the period up to the end of 2008 is to be able to submit permit applications for the encapsulation plant and the deep repository. This RD and D-Programme therefore differs from the preceding ones in that it concentrates on questions relating to technology development for these facilities. The programmes for safety assessment and research on the long-term processes that take place in the deep repository are then linked together with the programmes for technology development. Another

  5. Computational challenges and human factors influencing the design and use of clinical research participant eligibility pre-screening tools

    Science.gov (United States)

    2012-01-01

    Background Clinical trials are the primary mechanism for advancing clinical care and evidenced-based practice, yet challenges with the recruitment of participants for such trials are widely recognized as a major barrier to these types of studies. Data warehouses (DW) store large amounts of heterogenous clinical data that can be used to enhance recruitment practices, but multiple challenges exist when using a data warehouse for such activities, due to the manner of collection, management, integration, analysis, and dissemination of the data. A critical step in leveraging the DW for recruitment purposes is being able to match trial eligibility criteria to discrete and semi-structured data types in the data warehouse, though trial eligibility criteria tend to be written without concern for their computability. We present the multi-modal evaluation of a web-based tool that can be used for pre-screening patients for clinical trial eligibility and assess the ability of this tool to be practically used for clinical research pre-screening and recruitment. Methods The study used a validation study, usability testing, and a heuristic evaluation to evaluate and characterize the operational characteristics of the software as well as human factors affecting its use. Results Clinical trials from the Division of Cardiology and the Department of Family Medicine were used for this multi-modal evaluation, which included a validation study, usability study, and a heuristic evaluation. From the results of the validation study, the software demonstrated a positive predictive value (PPV) of 54.12% and 0.7%, respectively, and a negative predictive value (NPV) of 73.3% and 87.5%, respectively, for two types of clinical trials. Heuristic principles concerning error prevention and documentation were characterized as the major usability issues during the heuristic evaluation. Conclusions This software is intended to provide an initial list of eligible patients to a clinical study

  6. Computational challenges and human factors influencing the design and use of clinical research participant eligibility pre-screening tools

    Directory of Open Access Journals (Sweden)

    Pressler Taylor R

    2012-05-01

    Full Text Available Abstract Background Clinical trials are the primary mechanism for advancing clinical care and evidenced-based practice, yet challenges with the recruitment of participants for such trials are widely recognized as a major barrier to these types of studies. Data warehouses (DW store large amounts of heterogenous clinical data that can be used to enhance recruitment practices, but multiple challenges exist when using a data warehouse for such activities, due to the manner of collection, management, integration, analysis, and dissemination of the data. A critical step in leveraging the DW for recruitment purposes is being able to match trial eligibility criteria to discrete and semi-structured data types in the data warehouse, though trial eligibility criteria tend to be written without concern for their computability. We present the multi-modal evaluation of a web-based tool that can be used for pre-screening patients for clinical trial eligibility and assess the ability of this tool to be practically used for clinical research pre-screening and recruitment. Methods The study used a validation study, usability testing, and a heuristic evaluation to evaluate and characterize the operational characteristics of the software as well as human factors affecting its use. Results Clinical trials from the Division of Cardiology and the Department of Family Medicine were used for this multi-modal evaluation, which included a validation study, usability study, and a heuristic evaluation. From the results of the validation study, the software demonstrated a positive predictive value (PPV of 54.12% and 0.7%, respectively, and a negative predictive value (NPV of 73.3% and 87.5%, respectively, for two types of clinical trials. Heuristic principles concerning error prevention and documentation were characterized as the major usability issues during the heuristic evaluation. Conclusions This software is intended to provide an initial list of eligible patients to a

  7. Research tools to investigate movements, migrations, and life history of sturgeons (Acipenseridae, with an emphasis on marine-oriented populations.

    Directory of Open Access Journals (Sweden)

    Troy C Nelson

    Full Text Available Worldwide, sturgeons (Acipenseridae are among the most endangered fishes due to habitat degradation, overfishing, and inherent life history characteristics (long life span, late maturation, and infrequent spawning. As most sturgeons are anadromous, a considerable portion of their life history occurs in estuarine and marine environments where they may encounter unique threats (e.g., interception in non-target fisheries. Of the 16 marine-oriented species, 12 are designated as Critically Endangered by the IUCN, and these include species commercially harvested. We review important research tools and techniques (tagging, electronic tagging, genetics, microchemistry, observatory and discuss the comparative utility of these techniques to investigate movements, migrations, and life-history characteristics of sturgeons. Examples are provided regarding what the applications have revealed regarding movement and migration and how this information can be used for conservation and management. Through studies that include Gulf (Acipenser oxyrinchus desotoi and Green Sturgeon (A. medirostris, we illustrate what is known about well-studied species and then explore lesser-studied species. A more complete picture of migration is available for North American sturgeon species, while European and Asian species, which are among the most endangered sturgeons, are less understood. We put forth recommendations that encourage the support of stewardship initiatives to build awareness and provide key information for population assessment and monitoring.

  8. Research Tools to Investigate Movements, Migrations, and Life History of Sturgeons (Acipenseridae), with an Emphasis on Marine-Oriented Populations

    Science.gov (United States)

    Nelson, Troy C.; Doukakis, Phaedra; Lindley, Steven T.; Schreier, Andrea D.; Hightower, Joseph E.; Hildebrand, Larry R.; Whitlock, Rebecca E.; Webb, Molly A. H.

    2013-01-01

    Worldwide, sturgeons (Acipenseridae) are among the most endangered fishes due to habitat degradation, overfishing, and inherent life history characteristics (long life span, late maturation, and infrequent spawning). As most sturgeons are anadromous, a considerable portion of their life history occurs in estuarine and marine environments where they may encounter unique threats (e.g., interception in non-target fisheries). Of the 16 marine-oriented species, 12 are designated as Critically Endangered by the IUCN, and these include species commercially harvested. We review important research tools and techniques (tagging, electronic tagging, genetics, microchemistry, observatory) and discuss the comparative utility of these techniques to investigate movements, migrations, and life-history characteristics of sturgeons. Examples are provided regarding what the applications have revealed regarding movement and migration and how this information can be used for conservation and management. Through studies that include Gulf (Acipenser oxyrinchus desotoi) and Green Sturgeon (A. medirostris), we illustrate what is known about well-studied species and then explore lesser-studied species. A more complete picture of migration is available for North American sturgeon species, while European and Asian species, which are among the most endangered sturgeons, are less understood. We put forth recommendations that encourage the support of stewardship initiatives to build awareness and provide key information for population assessment and monitoring. PMID:23990959

  9. Environmental assessment as a planning tool for the decommissioning of a nuclear research facility in Canada

    International Nuclear Information System (INIS)

    Klukas, M.H.; Grondin, D.J.; Helbrecht, R.A.

    2002-01-01

    Whiteshell Laboratories, a nuclear research facility operated by Atomic Energy of Canada Ltd. (AECL), have provided research facilities for the Canadian Nuclear Industry since the early 1960's. In 1997, AECL made a business decision to discontinue research programs and operations at the laboratories. Shortly thereafter the decision was made in agreement with the Federal Government of Canada to decommission the laboratories. In compliance with its own policy and to meet the requirements of the Canadian Legislation, AECL assessed the potential environmental effects of the project. The Environmental Assessment included studies to evaluate he feasibility of leaving two major project components in place; low-level radioactive waste in trenches located at the Whiteshell Laboratories site and river sediments contaminated from operational effluent releases. For both project components, it was determined that managing the wastes in the existing location was environmentally sound. An extensive follow-up program, comprising of additional monitoring and analysis to verify these findings will be implemented. As a result of these assessments and the assessments for other project components it was concluded that the project was not likely to cause significant adverse effects. The assessment decision was accepted by the Minister of the Environment in 2002 April. (author)

  10. Archive eggs: a research and management tool for avian conservation breeding

    Science.gov (United States)

    Smith, Des H.V.; Moehrenschlager, Axel; Christensen, Nancy; Knapik, Dwight; Gibson, Keith; Converse, Sarah J.

    2012-01-01

    Worldwide, approximately 168 bird species are captive-bred for reintroduction into the wild. Programs tend to be initiated for species with a high level of endangerment. Depressed hatching success can be a problem for such programs and has been linked to artificial incubation. The need for artificial incubation is driven by the practice of multiclutching to increase egg production or by uncertainty over the incubation abilities of captive birds. There has been little attempt to determine how artificial incubation differs from bird-contact incubation. We describe a novel archive (data-logger) egg and use it to compare temperature, humidity, and egg-turning in 5 whooping crane (Grus americana) nests, 4 sandhill crane (G. canadensis) nests, and 3 models of artificial incubator; each of which are used to incubate eggs in whooping crane captive-breeding programs. Mean incubation temperature was 31.7° C for whooping cranes and 32.83° C for sandhill cranes. This is well below that of the artificial incubators (which were set based on a protocol of 37.6° C). Humidity in crane nests varied considerably, but median humidity in all 3 artificial incubators was substantially different from that in the crane nests. Two artificial incubators failed to turn the eggs in a way that mimicked crane egg-turning. Archive eggs are an effective tool for guiding the management of avian conservation breeding programs, and can be custom-made for other species. They also have potential to be applied to research on wild populations.

  11. High resolution X-ray emission spectroscopy: An advanced tool for actinide research

    Science.gov (United States)

    Vitova, T.; Brendebach, B.; Dardenne, K.; Denecke, M. A.; Lebid, A.; Löble, M.; Rothe, J.; Batuk, O. N.; Hormes, J.; Liu, D.; Breher, F.; Geckeis, H.

    2010-03-01

    High resolution X-ray emission spectroscopy (HRXES) is becoming increasingly important for our understanding of electronic and coordination structures. The combination of such information with development of quantum theoretical tools will advance our capability for predicting reactivity and physical behavior especially of 5f elements. HRXES can be used to remove lifetime broadening by registering the partial fluorescence yield emitted by the sample (i.e., recording a windowed signal from the energy dispersed fluorescence emission while varying incident photon energy), thereby yielding highly resolved X-ray absorption fine structure (XAFS) spectra. Such spectra often display resonant features not observed in conventional XAFS. The spectrometer set-up can also be used for a wide range of other experiments, for example, resonant inelastic X-ray scattering (RIXS), where bulk electron configuration information in solids, liquids and gases is obtained. Valence-selective XAFS studies, where the local structure of a selected element's valence state present in a mixture of valence states can be obtained, as well as site-selective XAFS studies, where the coordination structure of a metal bound to selected elements can be differentiated from that of all the other ligating atoms. A HRXES spectrometer has been constructed and is presently being commissioned for use at the INE-Beamline for actinide research at the synchrotron source ANKA at FZK. We present the spectrometer's compact, modular design, optimized for attaining a wide range of energies, and first test measurement results. Examples from HRXES studies of lanthanides, actinides counter parts, are also shown.

  12. Evolution of poor reporting and inadequate methods over time in 20 920 randomised controlled trials included in Cochrane reviews: research on research study.

    Science.gov (United States)

    Dechartres, Agnes; Trinquart, Ludovic; Atal, Ignacio; Moher, David; Dickersin, Kay; Boutron, Isabelle; Perrodeau, Elodie; Altman, Douglas G; Ravaud, Philippe

    2017-06-08

    Objective  To examine how poor reporting and inadequate methods for key methodological features in randomised controlled trials (RCTs) have changed over the past three decades. Design  Mapping of trials included in Cochrane reviews. Data sources  Data from RCTs included in all Cochrane reviews published between March 2011 and September 2014 reporting an evaluation of the Cochrane risk of bias items: sequence generation, allocation concealment, blinding, and incomplete outcome data. Data extraction  For each RCT, we extracted consensus on risk of bias made by the review authors and identified the primary reference to extract publication year and journal. We matched journal names with Journal Citation Reports to get 2014 impact factors. Main outcomes measures  We considered the proportions of trials rated by review authors at unclear and high risk of bias as surrogates for poor reporting and inadequate methods, respectively. Results  We analysed 20 920 RCTs (from 2001 reviews) published in 3136 journals. The proportion of trials with unclear risk of bias was 48.7% for sequence generation and 57.5% for allocation concealment; the proportion of those with high risk of bias was 4.0% and 7.2%, respectively. For blinding and incomplete outcome data, 30.6% and 24.7% of trials were at unclear risk and 33.1% and 17.1% were at high risk, respectively. Higher journal impact factor was associated with a lower proportion of trials at unclear or high risk of bias. The proportion of trials at unclear risk of bias decreased over time, especially for sequence generation, which fell from 69.1% in 1986-1990 to 31.2% in 2011-14 and for allocation concealment (70.1% to 44.6%). After excluding trials at unclear risk of bias, use of inadequate methods also decreased over time: from 14.8% to 4.6% for sequence generation and from 32.7% to 11.6% for allocation concealment. Conclusions  Poor reporting and inadequate methods have decreased over time, especially for sequence generation

  13. Tools for Virtual Collaboration Designed for High Resolution Hydrologic Research with Continental-Scale Data Support

    Science.gov (United States)

    Duffy, Christopher; Leonard, Lorne; Shi, Yuning; Bhatt, Gopal; Hanson, Paul; Gil, Yolanda; Yu, Xuan

    2015-04-01

    Using a series of recent examples and papers we explore some progress and potential for virtual (cyber-) collaboration inspired by access to high resolution, harmonized public-sector data at continental scales [1]. The first example describes 7 meso-scale catchments in Pennsylvania, USA where the watershed is forced by climate reanalysis and IPCC future climate scenarios (Intergovernmental Panel on Climate Change). We show how existing public-sector data and community models are currently able to resolve fine-scale eco-hydrologic processes regarding wetland response to climate change [2]. The results reveal that regional climate change is only part of the story, with large variations in flood and drought response associated with differences in terrain, physiography, landuse and/or hydrogeology. The importance of community-driven virtual testbeds are demonstrated in the context of Critical Zone Observatories, where earth scientists from around the world are organizing hydro-geophysical data and model results to explore new processes that couple hydrologic models with land-atmosphere interaction, biogeochemical weathering, carbon-nitrogen cycle, landscape evolution and ecosystem services [3][4]. Critical Zone cyber-research demonstrates how data-driven model development requires a flexible computational structure where process modules are relatively easy to incorporate and where new data structures can be implemented [5]. From the perspective of "Big-Data" the paper points out that extrapolating results from virtual observatories to catchments at continental scales, will require centralized or cloud-based cyberinfrastructure as a necessary condition for effectively sharing petabytes of data and model results [6]. Finally we outline how innovative cyber-science is supporting earth-science learning, sharing and exploration through the use of on-line tools where hydrologists and limnologists are sharing data and models for simulating the coupled impacts of catchment

  14. Research of a smart cutting tool based on MEMS strain gauge

    Science.gov (United States)

    Zhao, Y.; Zhao, Y. L.; Shao, YW; Hu, T. J.; Zhang, Q.; Ge, X. H.

    2018-03-01

    Cutting force is an important factor that affects machining accuracy, cutting vibration and tool wear. Machining condition monitoring by cutting force measurement is a key technology for intelligent manufacture. Current cutting force sensors exist problems of large volume, complex structure and poor compatibility in practical application, for these problems, a smart cutting tool is proposed in this paper for cutting force measurement. Commercial MEMS (Micro-Electro-Mechanical System) strain gauges with high sensitivity and small size are adopted as transducing element of the smart tool, and a structure optimized cutting tool is fabricated for MEMS strain gauge bonding. Static calibration results show that the developed smart cutting tool is able to measure cutting forces in both X and Y directions, and the cross-interference error is within 3%. Its general accuracy is 3.35% and 3.27% in X and Y directions, and sensitivity is 0.1 mV/N, which is very suitable for measuring small cutting forces in high speed and precision machining. The smart cutting tool is portable and reliable for practical application in CNC machine tool.

  15. Latest Community Coordinated Modeling Center (CCMC) services and innovative tools supporting the space weather research and operational communities.

    Science.gov (United States)

    Mendoza, A. M. M.; Rastaetter, L.; Kuznetsova, M. M.; Mays, M. L.; Chulaki, A.; Shim, J. S.; MacNeice, P. J.; Taktakishvili, A.; Collado-Vega, Y. M.; Weigand, C.; Zheng, Y.; Mullinix, R.; Patel, K.; Pembroke, A. D.; Pulkkinen, A. A.; Boblitt, J. M.; Bakshi, S. S.; Tsui, T.

    2017-12-01

    The Community Coordinated Modeling Center (CCMC), with the fundamental goal of aiding the transition of modern space science models into space weather forecasting while supporting space science research, has been serving as an integral hub for over 15 years, providing invaluable resources to both space weather scientific and operational communities. CCMC has developed and provided innovative web-based point of access tools varying from: Runs-On-Request System - providing unprecedented global access to the largest collection of state-of-the-art solar and space physics models, Integrated Space Weather Analysis (iSWA) - a powerful dissemination system for space weather information, Advanced Online Visualization and Analysis tools for more accurate interpretation of model results, Standard Data formats for Simulation Data downloads, and Mobile apps to view space weather data anywhere to the scientific community. In addition to supporting research and performing model evaluations, CCMC also supports space science education by hosting summer students through local universities. In this poster, we will showcase CCMC's latest innovative tools and services, and CCMC's tools that revolutionized the way we do research and improve our operational space weather capabilities. CCMC's free tools and resources are all publicly available online (http://ccmc.gsfc.nasa.gov).

  16. Research Electronic Data Capture (REDCap®) used as an audit tool with a built-in database.

    Science.gov (United States)

    Kragelund, Signe H; Kjærsgaard, Mona; Jensen-Fangel, Søren; Leth, Rita A; Ank, Nina

    2018-04-09

    The aim of this study was to develop an audit tool with a built-in database using Research Electronic Data Capture (REDCap®) as part of an antimicrobial stewardship program at a regional hospital in the Central Denmark Region, and to analyse the need, if any, to involve more than one expert in the evaluation of cases of antimicrobial treatment, and the level of agreement among the experts. Patients treated with systemic antimicrobials in the period from 1 September 2015 to 31 August 2016 were included, in total 722 cases. Data were collected retrospectively and entered manually. The audit was based on seven flow charts regarding: 1) initiation of antimicrobial treatment 2) infection 3) prescription and administration of antimicrobials 4) discontinuation of antimicrobials 5) reassessment within 48 hours after the first prescription of antimicrobials 6) microbiological sampling in the period between suspicion of infection and the first administration of antimicrobials 7) microbiological results. The audit was based on automatic calculations drawing on the entered data and on expert assessments. Initially, two experts completed the audit, and in the cases in which they disagreed, a third expert was consulted. In 31.9% of the cases, the two experts agreed on all elements of the audit. In 66.2%, the two experts reached agreement by discussing the cases. Finally, 1.9% of the cases were completed in cooperation with a third expert. The experts assessed 3,406 flow charts of which they agreed on 75.8%. We succeeded in creating an audit tool with a built-in database that facilitates independent expert evaluation using REDCap. We found a large inter-observer difference that needs to be considered when constructing a project based on expert judgements. Our two experts agreed on most of the flow charts after discussion, whereas the third expert's intervention did not have any influence on the overall assessment. Copyright © 2018. Published by Elsevier Inc.

  17. Report: Follow-Up Review - EPA Updated Information for Indoor Mold Research Tools

    Science.gov (United States)

    Report #16-P-0308, September 8, 2016. Corrective actions taken by the EPA should help ensure that the public has correct information about EPA approved technology and tools for evaluating indoor mold.

  18. The Danish Ventral Hernia Database – a valuable tool for quality assessment and research

    Directory of Open Access Journals (Sweden)

    Helgstrand F

    2016-10-01

    Full Text Available Frederik Helgstrand,1 Lars Nannestad Jorgensen2 1Department of Surgery, Køge Hospital, University of Copenhagen, Køge, Denmark; 2Digestive Disease Center, Bispebjerg Hospital, University of Copenhagen, Copenhagen NV, Denmark Aim: The Danish Ventral Hernia Database (DVHD provides national surveillance of current surgical practice and clinical postoperative outcomes. The intention is to reduce postoperative morbidity and hernia recurrence, evaluate new treatment strategies, and facilitate nationwide implementation of evidence-based treatment strategies. This paper describes the design and purpose of DVHD. Study population: Adult (≥18 years patients with a Danish Civil Registration Number and undergoing surgery under elective or emergency conditions for ventral hernia in a Danish surgical department from 2007 and beyond. A total of 80% of all ventral hernia repairs performed in Denmark were reported to the DVHD. Main variables: Demographic data (age, sex, and center, detailed hernia description (eg, type, size, surgical priority, and technical aspects (open/laparoscopic and mesh related factors related to the surgical repair are recorded. Data registration is mandatory. Data may be merged with other Danish health registries and information from patient questionnaires or clinical examinations. Descriptive data: More than 37,000 operations have been registered. Data have demonstrated high agreement with patient files. The data allow technical proposals for surgical improvement with special emphasis on reduced incidences of postoperative complications, hernia recurrence, and chronic pain. Conclusion: DVHD is a prospective and mandatory registration system for Danish surgeons. It has collected a high number of operations and is an excellent tool for observing changes over time, including adjustment of several confounders. This national database registry has impacted on clinical practice in Denmark and led to a high number of scientific publications

  19. The new alchemy: Online networking, data sharing and research activity distribution tools for scientists [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Antony J. Williams

    2017-08-01

    Full Text Available There is an abundance of free online tools accessible to scientists and others that can be used for online networking, data sharing and measuring research impact. Despite this, few scientists know how these tools can be used or fail to take advantage of using them as an integrated pipeline to raise awareness of their research outputs. In this article, the authors describe their experiences with these tools and how they can make best use of them to make their scientific research generally more accessible, extending its reach beyond their own direct networks, and communicating their ideas to new audiences. These efforts have the potential to drive science by sparking new collaborations and interdisciplinary research projects that may lead to future publications, funding and commercial opportunities. The intent of this article is to: describe some of these freely accessible networking tools and affiliated products; demonstrate from our own experiences how they can be utilized effectively; and, inspire their adoption by new users for the benefit of science.

  20. Correction Notice: Tools for Citizen-Science Recruitment and Student Engagement in Your Research and in Your Classroom

    Directory of Open Access Journals (Sweden)

    JMBE Production Editor

    2016-05-01

    Full Text Available Correction for Sarah E. Council and Julie E. Horvath, “Tools for Citizen-Science Recruitment and Student Engagement in Your Research and in Your Classroom,” which appeared in the Journal of Microbiology & Biology Education, volume 17, number 1, March 2016, pages 38–40.

  1. Understanding How Students Study: The Genealogy and Conceptual Basis of a Widely Used Pedagogical Research Tool, Biggs' Study Process Questionnaire

    Science.gov (United States)

    Lake, Warren; Boyd, William; Boyd, Wendy

    2017-01-01

    The Study Process Questionnaire (SPQ) continues to be applied in a wide range of pedagogical situations. However, the question remains as to how well a researcher understands the conceptual basis behind the tool they choose. This essay provides a compact and comprehensive view of the conceptual basis for the development of the original SPQ, and…

  2. Google vs. the Library: Student Preferences and Perceptions when Doing Research Using Google and a Federated Search Tool

    Science.gov (United States)

    Georgas, Helen

    2013-01-01

    Federated searching was once touted as the library world's answer to Google, but ten years since federated searching technology's inception, how does it actually compare? This study focuses on undergraduate student preferences and perceptions when doing research using both Google and a federated search tool. Students were asked about their…

  3. Molecular images as a tool in research. From radiopharmacy to radiopharmacology

    International Nuclear Information System (INIS)

    Zubillaga, M.

    2008-01-01

    Full text: The rapidly emerging biomedical research discipline of Molecular Imaging (MI) enables the visualization, characterization and quantification of biologic process taking place at the cellular and sub-cellular levels within the intact living organism. The overall goal of MI is to interrogate biologic process in the cell of a living subject to report on and reveal their molecular abnormalities that form the basis of disease. This is in contrast to classical diagnostic imaging where documented findings are the result of the end effects of these molecular alterations, usually in the form of macroscopic and well-established gross pathology. MI includes the field of Nuclear Medicine (SPECT and PET) and other strategies that do not depend on radioactivity to produce imaging signals (optical, bioluminescence and Magnetic Resonance). The emergence of MI strategies has made possible the achievement of several important biomedical research goals that open the door to advancement of study in molecular medicine. These various accomplishments include: (1) development of non invasive 'in vivo' imaging methods to reflect gene expression and more complex events such as protein-protein interactions; (2) ability to monitor multiple molecular events near simultaneously; (3) capacity to follow cell trafficking and cell targeting; (4) optimization of drug and gene therapy; (5) capability of imaging drug effects at a molecular and cellular level; (6) assessment of disease progression at a molecular pathologic level; (7) advancement of the possibility of achieving all the above mentioned goals rapidly, reproducibly and quantitatively, in support of monitoring a time-dependent manner the experimental, developmental, environmental and therapeutic influences on gene products in a single living subject. Although many laboratory based proof-of-principle and validation studies have been conducted using MI approaches, a great deal more experimental research will be necessary to

  4. CERN Open Data Portal - Improving usability and user experience of CMS Open Data research tools.

    CERN Document Server

    Hirvonsalo, Harri

    2015-01-01

    This report summarizes the work I have done during my assignment as participant of CERN Summer Students 2015 programme. Main goal of my Summer Student project was to lower the bar for people to start utilizing open data that CMS experiment has released in November 2014 to CERN Open Data Portal (http://opendata.cern.ch). Project included various working packages and tasks, such as: -Determine the obstacles that potential users of CMS research oriented open data who don’t have previous knowledge about internal workflow of analysis tasks at CMS experiment would run into. -Produce more introductory material and tutorials for conducting basic physics analyses with CMSSW to CERN Open Data Portal. -Study the feasibility of podio-framework (https://github.com/hegner/podio) for CMS Open Data users. The project work was done under the supervision of Kati Lassila-Perini whom I thank greatly for her help, patience and support.

  5. Teaching Spatial Thinking in Undergraduate Geology Courses Using Tools and Strategies from Cognitive Science Research

    Science.gov (United States)

    Ormand, C. J.; Shipley, T. F.; Dutrow, B. L.; Goodwin, L. B.; Hickson, T. A.; Tikoff, B.; Atit, K.; Gagnier, K. M.; Resnick, I.

    2015-12-01

    Spatial visualization is an essential skill in the STEM disciplines, including the geological sciences. Undergraduate students, including geoscience majors in upper-level courses, bring a wide range of spatial skill levels to the classroom. Students with weak spatial skills may struggle to understand fundamental concepts and to solve geological problems with a spatial component. However, spatial thinking skills are malleable. Using strategies that have emerged from cognitive science research, we developed a set of curricular materials that improve undergraduate geology majors' abilities to reason about 3D concepts and to solve spatially complex geological problems. Cognitive science research on spatial thinking demonstrates that predictive sketching, making visual comparisons, gesturing, and the use of analogy can be used to develop students' spatial thinking skills. We conducted a three-year study of the efficacy of these strategies in strengthening the spatial skills of students in core geology courses at three universities. Our methodology is a quasi-experimental quantitative design, utilizing pre- and post-tests of spatial thinking skills, assessments of spatial problem-solving skills, and a control group comprised of students not exposed to our new curricular materials. Students taught using the new curricular materials show improvement in spatial thinking skills. Further analysis of our data, to be completed prior to AGU, will answer additional questions about the relationship between spatial skills and academic performance, spatial skills and gender, spatial skills and confidence, and the impact of our curricular materials on students who are struggling academically. Teaching spatial thinking in the context of discipline-based exercises has the potential to transform undergraduate education in the geological sciences by removing one significant barrier to success.

  6. Multiple imputation as a flexible tool for missing data handling in clinical research.

    Science.gov (United States)

    Enders, Craig K

    2017-11-01

    The last 20 years has seen an uptick in research on missing data problems, and most software applications now implement one or more sophisticated missing data handling routines (e.g., multiple imputation or maximum likelihood estimation). Despite their superior statistical properties (e.g., less stringent assumptions, greater accuracy and power), the adoption of these modern analytic approaches is not uniform in psychology and related disciplines. Thus, the primary goal of this manuscript is to describe and illustrate the application of multiple imputation. Although maximum likelihood estimation is perhaps the easiest method to use in practice, psychological data sets often feature complexities that are currently difficult to handle appropriately in the likelihood framework (e.g., mixtures of categorical and continuous variables), but relatively simple to treat with imputation. The paper describes a number of practical issues that clinical researchers are likely to encounter when applying multiple imputation, including mixtures of categorical and continuous variables, item-level missing data in questionnaires, significance testing, interaction effects, and multilevel missing data. Analysis examples illustrate imputation with software packages that are freely available on the internet. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. [High fidelity simulation : a new tool for learning and research in pediatrics].

    Science.gov (United States)

    Bragard, I; Farhat, N; Seghaye, M-C; Schumacher, K

    2016-10-01

    Caring for a sick child represents a high risk activity that requires technical and non-technical skills related to several factors such as the rarity of certain events or the stress of caring for a child. As regard these conditions, medi¬cal simulation provides a learning environment without risk, the control of variables, the reproducibility of situations, and the confrontation with rare events. In this article, we des¬cribe the steps of a simulation session and outline the current knowledge of the use of simulation in paediatrics. A session of simulation includes seven phases following the model of Peter Dieckmann, particularly the scenario and the debriefing that form the heart of the learning experience. Several studies have shown the advantages of simulation for paediatric trai¬ning in terms of changes in attitudes, skills and knowledge. Some studies have demonstrated a beneficial transfer to prac¬tice. In conclusion, simulation provides great potential for training and research in paediatrics. The establishment of a collaborative research program by the whole simulation com¬munity would help ensure that this type of training improves the quality of care.

  8. Including Youth with Intellectual Disabilities in Health Promotion Research: Development and Reliability of a Structured Interview to Assess the Correlates of Physical Activity among Youth

    Science.gov (United States)

    Curtin, Carol; Bandini, Linda G.; Must, Aviva; Phillips, Sarah; Maslin, Melissa C. T.; Lo, Charmaine; Gleason, James M.; Fleming, Richard K.; Stanish, Heidi I.

    2016-01-01

    Background: The input of youth with intellectual disabilities in health promotion and health disparities research is essential for understanding their needs and preferences. Regular physical activity (PA) is vital for health and well-being, but levels are low in youth generally, including those with intellectual disabilities. Understanding the…

  9. Improvement of basic food crops in Africa through plant breeding, including the use of induced mutations. Proceedings of a final research co-ordination meeting

    International Nuclear Information System (INIS)

    1997-07-01

    The Co-ordinated Research Programme (CRP) on Improvement of Basic Food Crops in Africa Through Plant Breeding, Including the Use of Induced Mutations, funded by the Italian Government, was initiated in 1989 in the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture. The primary objective of this CRP was to breed improved varieties of stable food crops of Africa with the main emphasis on the indigenous species and their local cultivars. The fourth and final Research Co-ordination meeting under the CRP was held in Naples, Italy from 30 October - 3 November 1995. This publication includes the reports, conclusions and recommendations made by the participants. We hope that it will be of value to researchers, students and policy makers alike in their endeavour to promote plant breeding and increase food productions in Africa. Refs, figs, tabs

  10. Low-Cost Air Quality Monitoring Tools: From Research to Practice (A Workshop Summary

    Directory of Open Access Journals (Sweden)

    Andrea L. Clements

    2017-10-01

    Full Text Available In May 2017, a two-day workshop was held in Los Angeles (California, U.S.A. to gather practitioners who work with low-cost sensors used to make air quality measurements. The community of practice included individuals from academia, industry, non-profit groups, community-based organizations, and regulatory agencies. The group gathered to share knowledge developed from a variety of pilot projects in hopes of advancing the collective knowledge about how best to use low-cost air quality sensors. Panel discussion topics included: (1 best practices for deployment and calibration of low-cost sensor systems, (2 data standardization efforts and database design, (3 advances in sensor calibration, data management, and data analysis and visualization, and (4 lessons learned from research/community partnerships to encourage purposeful use of sensors and create change/action. Panel discussions summarized knowledge advances and project successes while also highlighting the questions, unresolved issues, and technological limitations that still remain within the low-cost air quality sensor arena.

  11. Pou4f2 knock-in Cre mouse: A multifaceted genetic tool for vision researchers.

    Science.gov (United States)

    Simmons, Aaron B; Bloomsburg, Samuel J; Billingslea, Samuel A; Merrill, Morgan M; Li, Shuai; Thomas, Marshall W; Fuerst, Peter G

    2016-01-01

    superior colliculus. Pou4f2(Cre) provides multiple uses for the vision researcher's genetic toolkit. First, Pou4f2(Cre) is a knock-in allele that can be used to eliminate Pou4f2, resulting in depletion of RGCs. Second, expression of Cre in male germ cells makes this strain an efficient germline activator of recombination, for example, to target LoxP-flanked sequences in the whole mouse. Third, Pou4f2(Cre) efficiently targets RGCs, amacrine cells, bipolar cells, horizontal cells, and a small number of photoreceptors within the retina, as well as the visual centers in the brain. Unlike other Cre recombinase lines that target retinal neurons, no recombination was observed in Müller or other retinal glia. These properties make this Cre recombinase line a useful tool for vision researchers.

  12. A Critical Look at Biomedical Journals’ Policies on Animal Research by Use of a Novel Tool: The EXEMPLAR Scale

    Directory of Open Access Journals (Sweden)

    Ana Raquel Martins

    2015-04-01

    Full Text Available Animal research is not only regulated by legislation but also by self-regulatory mechanisms within the scientific community, which include biomedical journals’ policies on animal use. For editorial policies to meaningfully impact attitudes and practice, they must not only be put into effect by editors and reviewers, but also be set to high standards. We present a novel tool to classify journals’ policies on animal use—the EXEMPLAR scale—as well as an analysis by this scale of 170 journals publishing studies on animal models of three human diseases: Amyotrophic Lateral Sclerosis, Type-1 Diabetes and Tuberculosis. Results show a much greater focus of editorial policies on regulatory compliance than on other domains, suggesting a transfer of journals’ responsibilities to scientists, institutions and regulators. Scores were not found to vary with journals’ impact factor, country of origin or antiquity, but were, however, significantly higher for open access journals, which may be a result of their greater exposure and consequent higher public scrutiny.

  13. Exploring the Types of SMEs Which Could use Blogs as a Marketing Tool: a Proposed Future Research Agenda

    Directory of Open Access Journals (Sweden)

    Adeline Phaik Harn Chua

    2009-08-01

    Full Text Available Blogs appear to be gaining momentum as a marketing tool which can be used by organisations for such strategies and processes as branding, managing reputation, developing customer trust and loyalty, niche marketing, gathering marketing intelligence and promoting their online presence. There has been limited academic research in this area, and most significantly concerning the types of small and medium enterprises (SMEs for which blogs might have potential as a marketing tool. In an attempt to address the knowledge gap, this paper presents a future research agenda (in the form of research questions which can guide the eBusiness research community in conducting much needed studies in this area. This paper is particularly novel in that it aims to demonstrate how the heterogeneity of SMEs and their specific business uses of eBusiness technology such as blogs can form the central plank of a future research agenda. This is important because the existing eBusiness literature tends to treat eBusiness collectively rather than focusing on the specific business uses of different eBusiness technologies, and to treat SMEs as a homogeneous group. The paper concludes with a discussion of how this research agenda can form the basis of studies which use a range of different research methods, and how this "big picture" agenda approach might help the eBusiness research community build theory which better explains SME adoption and use of eBusiness.

  14. EXAMINING THE ROLE AND RESEARCH CHALLENGES OF SOCIAL MEDIA AS A TOOL FOR NONPROLIFERATION AND ARMS CONTROL TREATY VERIFICATION

    Energy Technology Data Exchange (ETDEWEB)

    Henry, Michael J.; Cramer, Nicholas O.; Benz, Jacob M.; Gastelum, Zoe N.; Kreyling, Sean J.; West, Curtis L.

    2014-05-13

    Traditional arms control treaty verification activities typically involve a combination of technical measurements via physical and chemical sensors, state declarations, political agreements, and on-site inspections involving international subject matter experts. However, the ubiquity of the internet, and the electronic sharing of data that it enables, has made available a wealth of open source information with the potential to benefit verification efforts. Open source information is already being used by organizations such as the International Atomic Energy Agency to support the verification of state-declared information, prepare inspectors for in-field activities, and to maintain situational awareness . The recent explosion in social media use has opened new doors to exploring the attitudes, moods, and activities around a given topic. Social media platforms, such as Twitter, Facebook, and YouTube, offer an opportunity for individuals, as well as institutions, to participate in a global conversation at minimal cost. Social media data can also provide a more data-rich environment, with text data being augmented with images, videos, and location data. The research described in this paper investigates the utility of applying social media signatures as potential arms control and nonproliferation treaty verification tools and technologies, as determined through a series of case studies. The treaty relevant events that these case studies touch upon include detection of undeclared facilities or activities, determination of unknown events recorded by the International Monitoring System (IMS), and the global media response to the occurrence of an Indian missile launch. The case studies examine how social media can be used to fill an information gap and provide additional confidence to a verification activity. The case studies represent, either directly or through a proxy, instances where social media information may be available that could potentially augment the evaluation

  15. ClinQC: a tool for quality control and cleaning of Sanger and NGS data in clinical research.

    Science.gov (United States)

    Pandey, Ram Vinay; Pabinger, Stephan; Kriegner, Albert; Weinhäusel, Andreas

    2016-02-02

    Traditional Sanger sequencing has been used as a gold standard method for genetic testing in clinic to perform single gene test, which has been a cumbersome and expensive method to test several genes in heterogeneous disease such as cancer. With the advent of Next Generation Sequencing technologies, which produce data on unprecedented speed in a cost effective manner have overcome the limitation of Sanger sequencing. Therefore, for the efficient and affordable genetic testing, Next Generation Sequencing has been used as a complementary method with Sanger sequencing for disease causing mutation identification and confirmation in clinical research. However, in order to identify the potential disease causing mutations with great sensitivity and specificity it is essential to ensure high quality sequencing data. Therefore, integrated software tools are lacking which can analyze Sanger and NGS data together and eliminate platform specific sequencing errors, low quality reads and support the analysis of several sample/patients data set in a single run. We have developed ClinQC, a flexible and user-friendly pipeline for format conversion, quality control, trimming and filtering of raw sequencing data generated from Sanger sequencing and three NGS sequencing platforms including Illumina, 454 and Ion Torrent. First, ClinQC convert input read files from their native formats to a common FASTQ format and remove adapters, and PCR primers. Next, it split bar-coded samples, filter duplicates, contamination and low quality sequences and generates a QC report. ClinQC output high quality reads in FASTQ format with Sanger quality encoding, which can be directly used in down-stream analysis. It can analyze hundreds of sample/patients data in a single run and generate unified output files for both Sanger and NGS sequencing data. Our tool is expected to be very useful for quality control and format conversion of Sanger and NGS data to facilitate improved downstream analysis and mutation

  16. A systematic review of active transportation research in Africa and the psychometric properties of measurement tools for children and youth.

    Science.gov (United States)

    Larouche, Richard; Oyeyemi, Adewale L; Prista, Antonio; Onywera, Vincent; Akinroye, Kingsley K; Tremblay, Mark S

    2014-10-18

    Previous systematic reviews indicate that active transportation (AT; the use of non-motorized travel modes such as walking, running and cycling) is an important source of daily physical activity (PA). However, no previous systematic review has examined travel behaviours among African children and youth or the psychometric properties of measurement tools used among children and youth worldwide. Studies on AT among African children and youth (aged 5-17 years) were identified through 1) the MEDLINE and Embase databases; 2) manual searches of six African journals that are not indexed in these databases; and 3) the articles included in a previous systematic review on PA among children and youth in Sub-Saharan Africa. Second, literature on the psychometric properties of measurement tools for children and youth was searched using the MEDLINE, Embase, Cochrane Central Register of Controlled Trials, PsycInfo, SportDiscus, and Health and Psychosocial Instruments databases. Study quality was assessed with a modified version of the Downs and Black checklist. Twenty studies reported original data on AT among African children and youth. This evidence suggests that rates of AT to/from school are lower in urban areas and in youth attending higher SES schools. Two population-based studies reported rates of AT ranging between 19.8% and 66.6% in multiple countries. Studies conducted in Africa seldom examined non-school travel and only one reported data on the psychometric properties of their measures of travel behaviours. Nineteen studies conducted predominantly in high-income countries provided psychometric data. Child and parent reports were used in 17 studies, and these measures generally showed substantial to almost perfect test-retest reliability and convergent validity for school trips. Limited information was available regarding non-school trips. Objective measures of travel behaviours have been used much less often, and further validity and reliability assessments are

  17. pClone: Synthetic Biology Tool Makes Promoter Research Accessible to Beginning Biology Students

    Science.gov (United States)

    Campbell, A. Malcolm; Eckdahl, Todd; Cronk, Brian; Andresen, Corinne; Frederick, Paul; Huckuntod, Samantha; Shinneman, Claire; Wacker, Annie; Yuan, Jason

    2014-01-01

    The "Vision and Change" report recommended genuine research experiences for undergraduate biology students. Authentic research improves science education, increases the number of scientifically literate citizens, and encourages students to pursue research. Synthetic biology is well suited for undergraduate research and is a growing area…

  18. Action Research: A Tool for Improving Teacher Quality and Classroom Practice

    Science.gov (United States)

    O'Connor, Katherine A.; Greene, H. Carol; Anderson, Patricia J.

    2006-01-01

    Background: Action research is a meaningful form of research because it is conducted by the teacher in his or her own classroom. Action research requires a teacher to design a study in an area of interest and conduct it in their own classroom. Action research is a requirement for some masters of education programs in the United States. Purpose: To…

  19. An informatics-based tool to assist researchers in initiating research at an academic medical center: Vanderbilt Customized Action Plan.

    Science.gov (United States)

    Pulley, Jill M; Harris, Paul A; Yarbrough, Tonya; Swafford, Jonathan; Edwards, Terri; Bernard, Gordon R

    2010-01-01

    The regulatory review and approval process is a significant part of the workflow associated with initiating clinical and translational research projects. Ambiguity concerning submission requirements and expected times associated with the review process can create additional work for research teams and ultimately delay important scientific projects. In an effort to provide assistance to investigators, we have developed an online interactive interface which elicits basic study characteristics for a single project and subsequently produces a list of required administrative applications needed for approval along with clear instructions concerning expectations from the research team. This system, the Vanderbilt Customized Action Plan (V-CAP), was launched in October 2006 and has been well received by researchers. In this article, the authors present (1) the V-CAP project design, (2) a reference workflow associated with Vanderbilt policies and regulations, (3) the V-CAP metrics of use by Vanderbilt research teams, and (4) a list of recommendations for other academic centers considering a similar systems-based approach for helping researchers efficiently navigate processes related to regulatory approval. The informatics-systems-based approach of the V-CAP is scalable to other academic medical centers and may serve as a useful model to help researchers navigate the complexity of the regulatory approvals process.

  20. Using publicly available internet tools to teach patent research and development

    DEFF Research Database (Denmark)

    Jensen, Søren; Tanev, Stoyan

    2013-01-01

    the university curriculum with appropriately designed courses focusing on patent development strategies. There is therefore a need for the development of such academic courses by using publicly available resources and by focusing on cost efficiency. The focus on the balance between cost and educational....... With the advancement of the internet a number of patent offices are offering online tools that can be utilized in the teaching of the patent system, we will provide a review and analysis of these tools resulting in a suggestion for a patent course syllabus corresponding to an average student workload of 5 ECTS....

  1. Research Results Of Stress-Strain State Of Cutting Tool When Aviation Materials Turning

    Science.gov (United States)

    Serebrennikova, A. G.; Nikolaeva, E. P.; Savilov, A. V.; Timofeev, S. A.; Pyatykh, A. S.

    2018-01-01

    Titanium alloys and stainless steels are hard-to-machine of all the machining types. Cutting edge state of turning tool after machining titanium and high-strength aluminium alloys and corrosion-resistant high-alloy steel has been studied. Cutting forces and chip contact arears with the rake surface of cutter has been measured. The relationship of cutting forces and residual stresses are shown. Cutting forces and residual stresses vs value of cutting tool rake angle relation were obtained. Measurements of residual stresses were performed by x-ray diffraction.

  2. Effective communication tools to engage Torres Strait Islanders in scientific research

    Science.gov (United States)

    Jones, A.; Barnett, B.; Williams, A. J.; Grayson, J.; Busilacchi, S.; Duckworth, A.; Evans-Illidge, E.; Begg, G. A.; Murchie, C. D.

    2008-09-01

    Often, research activities in Torres Strait have not delivered full benefit to Torres Strait Islanders due to a lack of consultation, ineffectual communication of research information and lack of empathy for the needs of Islander communities. As for other stakeholder groups, integration of Islanders into the research process through practical involvement in research may overcome these problems. Three case studies from research projects conducted in Torres Strait are discussed to highlight a variety of communication and engagement activities carried out by non-Indigenous researchers. How these communication and extension activities facilitate collaboration between Torres Strait Islander and non-Indigenous researchers provides insight in the importance of these activities to the relative success of research projects. The benefits for Islanders in collaborating with researchers may be: improved understanding of the research and how it contributes to natural resource management; a sense of control in future management decisions; a greater likelihood of successful self-regulatory management systems; enhanced skills; and increased employment opportunities. The potential benefits for researchers are enhanced support for research projects resulting in increased access to data and logistic support that may ultimately impact the successful completion of projects. Such an approach will require researchers to take time to develop relationships with Torres Strait Islanders, effectively involve Islanders in research on an equitable basis and be flexible. This will ultimately require funding organisations to recognise the importance of such activities in research proposals and provide support through sufficient funding to enable these activities to be carried out.

  3. Consortium on Methods Evaluating Tobacco: Research Tools to Inform FDA Regulation of Snus.

    Science.gov (United States)

    Berman, Micah L; Bickel, Warren K; Harris, Andrew C; LeSage, Mark G; O'Connor, Richard J; Stepanov, Irina; Shields, Peter G; Hatsukami, Dorothy K

    2017-10-04

    The U.S. Food and Drug Administration (FDA) has purview over tobacco products. To set policy, the FDA must rely on sound science, yet most existing tobacco research methods have not been designed to specifically inform regulation. The NCI and FDA-funded Consortium on Methods Evaluating Tobacco (COMET) was established to develop and assess valid and reliable methods for tobacco product evaluation. The goal of this paper is to describe these assessment methods using a U.S. manufactured "snus" as the test product. In designing studies that could inform FDA regulation, COMET has taken a multidisciplinary approach that includes experimental animal models and a range of human studies that examine tobacco product appeal, addictiveness, and toxicity. This paper integrates COMET's findings over the last 4 years. Consistency in results was observed across the various studies, lending validity to our methods. Studies showed low abuse liability for snus and low levels of consumer demand. Toxicity was less than cigarettes on some biomarkers but higher than medicinal nicotine. Using our study methods and the convergence of results, the snus that we tested as a potential modified risk tobacco product is likely to neither result in substantial public health harm nor benefit. This review describes methods that were used to assess the appeal, abuse liability, and toxicity of snus. These methods included animal, behavioral economics, and consumer perception studies, and clinical trials. Across these varied methods, study results showed low abuse-liability and appeal of the snus product we tested. In several studies, demand for snus was lower than for less toxic nicotine gum. The consistency and convergence of results across a range of multi-disciplinary studies lends validity to our methods and suggests that promotion of snus as a modified risk tobacco products is unlikely to produce substantial public health benefit or harm. © The Author 2017. Published by Oxford University Press

  4. How Are Gender Equality and Human Rights Interventions Included in Sexual and Reproductive Health Programmes and Policies: A Systematic Review of Existing Research Foci and Gaps.

    Science.gov (United States)

    Hartmann, Miriam; Khosla, Rajat; Krishnan, Suneeta; George, Asha; Gruskin, Sofia; Amin, Avni

    2016-01-01

    The importance of promoting gender equality and human rights in sexual and reproductive health (SRH) programmes and policies has been affirmed in numerous international and regional agreements, most recently the 2030 Agenda for Sustainable Development. Given the critical role of research to determine what works, we aimed to identify research gaps as part of a broader priority setting exercise on integrating gender equality and human rights approaches in SRH programmes and policies. A systematic literature review of reviews was conducted to examine the question: what do we know about how research in the context of SRH programmes and policies has addressed gender equality and human rights and what are the current gaps in research. We searched three databases for reviews that addressed the research question, were published between 1994-2014, and met methodological standards for systematic reviews, qualitative meta-syntheses and other reviews of relevance to the research question. Additional grey literature was identified based on expert input. Articles were appraised by the primary author and examined by an expert panel. An abstraction and thematic analysis process was used to synthesize findings. Of the 3,073 abstracts identified, 56 articles were reviewed in full and 23 were included along with 10 from the grey literature. The majority focused on interventions addressing gender inequalities; very few reviews explicitly included human rights based interventions. Across both topics, weak study designs and use of intermediate outcome measures limited evidence quality. Further, there was limited evidence on interventions that addressed marginalized groups. Better quality studies, longer-term indicators, and measurement of unintended consequences are needed to better understand the impact of these types of interventions on SRH outcomes. Further efforts are needed to cover research on gender equality and human rights issues as they pertain to a broader set of SRH topics

  5. Recommendations for collaborative paediatric research including biobanking in Europe: a Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) initiative.

    Science.gov (United States)

    Kuemmerle-Deschner, Jasmin B; Hansmann, Sandra; Wulffraat, Nico M; Vastert, Sebastiaan J; Hens, Kristien; Anton, Jordi; Avcin, Tadej; Martini, Alberto; Koné-Paut, Isabelle; Uziel, Yosef; Ravelli, Angelo; Wouters, Carine; Shaw, David; Özen, Seza; Eikelberg, Andreas; Prakken, Berent J; Ruperto, Nicolino; Horneff, Gerd; Constantin, Tamas; Beresford, Michael W; Sikken, Marijn; Foster, Helen E; Haug, Iris; Schuller, Sabrina; Jägle, Christine; Benseler, Susanne M

    2018-03-01

    Innovative research in childhood rheumatic diseases mandates international collaborations. However, researchers struggle with significant regulatory heterogeneity; an enabling European Union (EU)-wide framework is missing. The aims of the study were to systematically review the evidence for best practice and to establish recommendations for collaborative research. The Paediatric Rheumatology European Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) project enabled a scoping review and expert discussion, which then informed the systematic literature review. Published evidence was synthesised; recommendations were drafted. An iterative review process and consultations with Ethics Committees and European experts for ethical and legal aspects of paediatric research refined the recommendations. SHARE experts and patient representatives vetted the proposed recommendations at a consensus meeting using Nominal Group Technique. Agreement of 80% was mandatory for inclusion. The systematic literature review returned 1319 records. A total of 223 full-text publications plus 22 international normative documents were reviewed; 85 publications and 16 normative documents were included. A total of 21 recommendations were established including general principles (1-3), ethics (4-7), paediatric principles (8 and 9), consent to paediatric research (10-14), paediatric databank and biobank (15 and 16), sharing of data and samples (17-19), and commercialisation and third parties (20 and 21). The refined recommendations resulted in an agreement of >80% for all recommendations. The SHARE initiative established the first recommendations for Paediatric Rheumatology collaborative research across borders in Europe. These provide strong support for an urgently needed European framework and evidence-based guidance for its implementation. Such changes will promote research in children with rheumatic diseases. © Article author(s) (or their employer(s) unless otherwise

  6. How Are Gender Equality and Human Rights Interventions Included in Sexual and Reproductive Health Programmes and Policies: A Systematic Review of Existing Research Foci and Gaps.

    Directory of Open Access Journals (Sweden)

    Miriam Hartmann

    Full Text Available The importance of promoting gender equality and human rights in sexual and reproductive health (SRH programmes and policies has been affirmed in numerous international and regional agreements, most recently the 2030 Agenda for Sustainable Development. Given the critical role of research to determine what works, we aimed to identify research gaps as part of a broader priority setting exercise on integrating gender equality and human rights approaches in SRH programmes and policies. A systematic literature review of reviews was conducted to examine the question: what do we know about how research in the context of SRH programmes and policies has addressed gender equality and human rights and what are the current gaps in research. We searched three databases for reviews that addressed the research question, were published between 1994-2014, and met methodological standards for systematic reviews, qualitative meta-syntheses and other reviews of relevance to the research question. Additional grey literature was identified based on expert input. Articles were appraised by the primary author and examined by an expert panel. An abstraction and thematic analysis process was used to synthesize findings. Of the 3,073 abstracts identified, 56 articles were reviewed in full and 23 were included along with 10 from the grey literature. The majority focused on interventions addressing gender inequalities; very few reviews explicitly included human rights based interventions. Across both topics, weak study designs and use of intermediate outcome measures limited evidence quality. Further, there was limited evidence on interventions that addressed marginalized groups. Better quality studies, longer-term indicators, and measurement of unintended consequences are needed to better understand the impact of these types of interventions on SRH outcomes. Further efforts are needed to cover research on gender equality and human rights issues as they pertain to a broader

  7. How Are Gender Equality and Human Rights Interventions Included in Sexual and Reproductive Health Programmes and Policies: A Systematic Review of Existing Research Foci and Gaps

    Science.gov (United States)

    Khosla, Rajat; Krishnan, Suneeta; George, Asha; Gruskin, Sofia; Amin, Avni

    2016-01-01

    The importance of promoting gender equality and human rights in sexual and reproductive health (SRH) programmes and policies has been affirmed in numerous international and regional agreements, most recently the 2030 Agenda for Sustainable Development. Given the critical role of research to determine what works, we aimed to identify research gaps as part of a broader priority setting exercise on integrating gender equality and human rights approaches in SRH programmes and policies. A systematic literature review of reviews was conducted to examine the question: what do we know about how research in the context of SRH programmes and policies has addressed gender equality and human rights and what are the current gaps in research. We searched three databases for reviews that addressed the research question, were published between 1994–2014, and met methodological standards for systematic reviews, qualitative meta-syntheses and other reviews of relevance to the research question. Additional grey literature was identified based on expert input. Articles were appraised by the primary author and examined by an expert panel. An abstraction and thematic analysis process was used to synthesize findings. Of the 3,073 abstracts identified, 56 articles were reviewed in full and 23 were included along with 10 from the grey literature. The majority focused on interventions addressing gender inequalities; very few reviews explicitly included human rights based interventions. Across both topics, weak study designs and use of intermediate outcome measures limited evidence quality. Further, there was limited evidence on interventions that addressed marginalized groups. Better quality studies, longer-term indicators, and measurement of unintended consequences are needed to better understand the impact of these types of interventions on SRH outcomes. Further efforts are needed to cover research on gender equality and human rights issues as they pertain to a broader set of SRH topics

  8. How hard can it be to include research evidence and evaluation in local health policy implementation? Results from a mixed methods study

    Directory of Open Access Journals (Sweden)

    Evans Bridie Angela

    2013-02-01

    Full Text Available Abstract Background Although an evidence-based approach is the ideal model for planning and delivering healthcare, barriers exist to using research evidence to implement and evaluate service change. This paper aims to inform policy implementation and evaluation by understanding the role of research evidence at the local level through implementation of a national chronic conditions management policy. Methods We conducted a national email survey of health service commissioners at the most devolved level of decision-making in Wales (Local Health Boards – LHBs followed by in-depth interviews with representatives of LHBs, purposively selecting five to reflect geographic and economic characteristics. Survey data were analysed descriptively; we used thematic analysis for interview data. Results All LHBs (n = 22 completed questionnaires. All reported they routinely assessed the research literature before implementing interventions, but free-text answers revealed wide variation in approach. Most commonly reported information sources included personal contacts, needs assessments, information or research databases. No consistent approach to evaluation was reported. Frequently reported challenges were: insufficient staff capacity (17/22; limited skills, cost, limited time, competing priorities (16/22; availability and quality of routine data (15/22. Respondents reported they would value central guidance on evaluation. Five interviews were held with managers from the five LHBs contacted. Service delivery decisions were informed by Welsh Government initiatives and priorities, budgets, perceived good practice, personal knowledge, and local needs, but did not include formal research evidence, they reported. Decision making was a collaborative process including clinical staff, patient representatives, and partner organization managers with varying levels of research experience. Robust evaluation data were required, but they were constrained by a lack of skills

  9. Profile Building, Research Sharing and Data Proliferation using Social Media Tools for Scientists (RTI presentation)

    Science.gov (United States)

    Many of us nowadays invest significant amounts of time in sharing our activities and opinions with friends and family via social networking tools such as Facebook, Twitter or other related websites. However, despite the availability of many platforms for scientists to connect and...

  10. The policy-relevancy of impact assessment tools: Evaluating nine years of European research funding

    NARCIS (Netherlands)

    Podhora, A.; Helming, K.; Adenauer, L.; Heckelei, T.; Kautto, P.; Reidsma, P.; Rennings, K.; Turnpenny, J.; Jansen, J.M.L.

    2013-01-01

    Since 2002, the European Commission has employed the instrument of ex-ante impact assessments (IA) to help focus its policy-making process on implementing sustainable development. Scientific tools should play an essential role of providing the evidence base to assess the impacts of alternative

  11. Characteristics and evolution of the ecosystem of software tools supporting research in molecular biology.

    Science.gov (United States)

    Pazos, Florencio; Chagoyen, Monica

    2018-01-16

    Daily work in molecular biology presently depends on a large number of computational tools. An in-depth, large-scale study of that 'ecosystem' of Web tools, its characteristics, interconnectivity, patterns of usage/citation, temporal evolution and rate of decay is crucial for understanding the forces that shape it and for informing initiatives aimed at its funding, long-term maintenance and improvement. In particular, the long-term maintenance of these tools is compromised because of their specific development model. Hundreds of published studies become irreproducible de facto, as the software tools used to conduct them become unavailable. In this study, we present a large-scale survey of >5400 publications describing Web servers within the two main bibliographic resources for disseminating new software developments in molecular biology. For all these servers, we studied their citation patterns, the subjects they address, their citation networks and the temporal evolution of these factors. We also analysed how these factors affect the availability of these servers (whether they are alive). Our results show that this ecosystem of tools is highly interconnected and adapts to the 'trendy' subjects in every moment. The servers present characteristic temporal patterns of citation/usage, and there is a worrying rate of server 'death', which is influenced by factors such as the server popularity and the institutions that hosts it. These results can inform initiatives aimed at the long-term maintenance of these resources. © The Author(s) 2018. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  12. А New Homo Economicus – is the Future Human Image: Methodological Research Tools

    Directory of Open Access Journals (Sweden)

    Oksana Petinova

    2014-07-01

    Full Text Available In this article the author focuses on the consideration of the features of the modeling method in the context of the methodology of the new economic man study. Attention is focused on the fact that the formation of the current global economic system is philosophical problematization of economic knowledge which contains search for new forms and methods of research and presentation not only in academic discourse, but also socially meaningful contexts. The author concludes that the subject area of the total review of the traditional model of economic man and designing new models in the framework of theoretical and empirical contexts involves interrelated economic, ideologi-cal, socio-cultural, psychological, spiritual, political, ethical segments that require philosophical comprehension. The economic motivation of human behavior in the system of market relations associated with existential axiological selection problems of care about the future of modern life with the problems of identifying opportunities, social values and ideals, a change for the better socio -economic life. We are talking about multifactor model that includes a wide range of features and integrated indicators of viability, but successfully replacing uncertain characteristics of a real object is completely defined by ideal projections. The viability of the model depends on its represen-tative capacity, combined with other models, completeness penetration of socially significant pro-gram of activities that define the norms of social and economic interaction between people, social and cultural continuity degree.

  13. NPASS: natural product activity and species source database for natural product research, discovery and tool development.

    Science.gov (United States)

    Zeng, Xian; Zhang, Peng; He, Weidong; Qin, Chu; Chen, Shangying; Tao, Lin; Wang, Yali; Tan, Ying; Gao, Dan; Wang, Bohua; Chen, Zhe; Chen, Weiping; Jiang, Yu Yang; Chen, Yu Zong

    2018-01-04

    There has been renewed interests in the exploration of natural products (NPs) for drug discovery, and continuous investigations of the therapeutic claims and mechanisms of traditional and herbal medicines. In-silico methods have been employed for facilitating these studies. These studies and the optimization of in-silico algorithms for NP applications can be facilitated by the quantitative activity and species source data of the NPs. A number of databases collectively provide the structural and other information of ∼470 000 NPs, including qualitative activity information for many NPs, but only ∼4000 NPs are with the experimental activity values. There is a need for the activity and species source data of more NPs. We therefore developed a new database, NPASS (Natural Product Activity and Species Source) to complement other databases by providing the experimental activity values and species sources of 35 032 NPs from 25 041 species targeting 5863 targets (2946 proteins, 1352 microbial species and 1227 cell-lines). NPASS contains 446 552 quantitative activity records (e.g. IC50, Ki, EC50, GI50 or MIC mainly in units of nM) of 222 092 NP-target pairs and 288 002 NP-species pairs. NPASS, http://bidd2.nus.edu.sg/NPASS/, is freely accessible with its contents searchable by keywords, physicochemical property range, structural similarity, species and target search facilities. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  14. Students' Framing of a Reading Annotation Tool in the Context of Research-Based Teaching

    Science.gov (United States)

    Dahl, Jan Erik

    2016-01-01

    In the studied master's course, students participated both as research objects in a digital annotation experiment and as critical investigators of this technology in their semester projects. The students' role paralleled the researcher's role, opening an opportunity for researcher-student co-learning within what is often referred to as…

  15. The development of a ranking tool for refereed journals in which nursing and midwifery researchers publish their work.

    Science.gov (United States)

    Crookes, Patrick A; Reis, Samantha L; Jones, Sandra C

    2010-07-01

    Publication in quality journals has long been a yardstick for measuring academic performance, although there is a divergence of opinions as to how to define and measure "journal quality". For some time the primary tools for assessing journal quality have been the ISI Journal Citation Reports and the Journal Impact Factors (JIFs), although it has been argued that these are less appropriate for practical disciplines such as nursing midwifery. In order to accurately reflect the nature of nursing and midwifery as a discipline, given the inherent flaws of using just one indicator of journal quality to assess performance overall, this project was designed to develop a tool which combined both objective and subjective methods to produce a ranking system which is specifically relevant to the disciplines of nursing and midwifery. This project succeeded in developing the Journal Evaluation Tool (JET), through extensive consultations with experts in the fields of nursing and midwifery. This tool may overcome some problems associated with the sole use of the journal impact factor, and may be utilised as an alternative measure of journal quality. The new tool was tested using a sample of 52 responding journals; and has now been disseminated to nursing and midwifery bodies in Australia and New Zealand, along with instructions for its use and recommendations for future research. Copyright 2009 Elsevier Ltd. All rights reserved.

  16. A Tropical Marine Microbial Natural Products Geobibliography as an Example of Desktop Exploration of Current Research Using Web Visualisation Tools

    Directory of Open Access Journals (Sweden)

    Elizabeth A. Evans-Illidge

    2008-10-01

    Full Text Available Microbial marine biodiscovery is a recent scientific endeavour developing at a time when information and other technologies are also undergoing great technical strides. Global visualisation of datasets is now becoming available to the world through powerful and readily available software such as Worldwind ™, ArcGIS Explorer ™ and Google Earth ™. Overlaying custom information upon these tools is within the hands of every scientist and more and more scientific organisations are making data available that can also be integrated into these global visualisation tools. The integrated global view that these tools enable provides a powerful desktop exploration tool. Here we demonstrate the value of this approach to marine microbial biodiscovery by developing a geobibliography that incorporates citations on tropical and near-tropical marine microbial natural products research with Google Earth ™ and additional ancillary global data sets. The tools and software used are all readily available and the reader is able to use and install the material described in this article.

  17. A GUI-based intuitive tool for analyzing formats and extracting contents of binary data in fusion research

    International Nuclear Information System (INIS)

    Naito, O.

    2015-01-01

    Highlights: • A GUI-based intuitive tool for data format analysis is presented. • Data can be viewed in any data types specified by the user in real time. • Analyzed formats are saved and reused as templates for other data of the same forms. • Users can easily extract contents in any forms by writing a simple script file. • The tool would be useful for exchanging data in collaborative fusion researches. - Abstract: An intuitive tool with graphical user interface (GUI) for analyzing formats and extracting contents of binary data in fusion research is presented. Users can examine structures of binary data at arbitrary addresses by selecting their type from a list of radio buttons in the data inspection window and checking their representations instantly on the computer screen. The result of analysis is saved in a file which contains the information such as name, data type, start address, and array size of the data. If the array size of some data depends on others that appear prior to the former and if the users specify their relation in the inspection window, the resultant file can also be used as a format template for the same series of data. By writing a simple script, the users can extract the contents of data either to a text or binary file in the format of their preference. As a real-life example, the tool is applied to the MHD equilibrium data at JT-60U, where poloidal flux data are extracted and converted to a format suitable for contour plotting in other data visualization program. The tool would be useful in collaborative fusion researches for exchanging relatively small-size data, which don’t fit in well with the standard routine processes

  18. Imaging Spectrograph as a Tool to Enhance the Undergraduate Student Research Experience

    Science.gov (United States)

    Williams, B.; Nielsen, K.; Johnson, S.

    2015-12-01

    Undergraduate students often engage in research activities that are part of a larger project outlined by research faculty, while it is less common for students to explore and define their own research project. The later has been shown to have tremendous impact on the learning outcome of the students and provide a stronger sense of pride and ownership of the research project. It is unrealistic to expect starting undergraduate students to define transformative research projects. However, with the proper training and guidance student-driven transformative research is possible for upper division students. We have instituted a student research paradigm with focus on the development of student research skills in coordination with their course progress. We present here a specific student project that engage students in aeronomy research activities and provide them with a solid base to establish their own research projects for senior year. The core of the project is an imaging spectrograph, which is constructed, tested, and calibrated by the students. The instrument provides unique opportunities student research projects across subject such as optics, quantum mechanics, and how these subjects are applied in the geosciences of aeronomy and space physics.

  19. Tools for Integrating Data Access from the IRIS DMC into Research Workflows

    Science.gov (United States)

    Reyes, C. G.; Suleiman, Y. Y.; Trabant, C.; Karstens, R.; Weertman, B. R.

    2012-12-01

    Web service interfaces at the IRIS Data Management Center (DMC) provide access to a vast archive of seismological and related geophysical data. These interfaces are designed to easily incorporate data access into data processing workflows. Examples of data that may be accessed include: time series data, related metadata, and earthquake information. The DMC has developed command line scripts, MATLAB® interfaces and a Java library to support a wide variety of data access needs. Users of these interfaces do not need to concern themselves with web service details, networking, or even (in most cases) data conversion. Fetch scripts allow access to the DMC archive and are a comfortable fit for command line users. These scripts are written in Perl and are well suited for automation and integration into existing workflows on most operating systems. For metdata and event information, the Fetch scripts even parse the returned data into simple text summaries. The IRIS Java Web Services Library (IRIS-WS Library) allows Java developers the ability to create programs that access the DMC archives seamlessly. By returning the data and information as native Java objects the Library insulates the developer from data formats, network programming and web service details. The MATLAB interfaces leverage this library to allow users access to the DMC archive directly from within MATLAB (r2009b or newer), returning data into variables for immediate use. Data users and research groups are developing other toolkits that use the DMC's web services. Notably, the ObsPy framework developed at LMU Munich is a Python Toolbox that allows seamless access to data and information via the DMC services. Another example is the MATLAB-based GISMO and Waveform Suite developments that can now access data via web services. In summary, there now exist a host of ways that researchers can bring IRIS DMC data directly into their workflows. MATLAB users can use irisFetch.m, command line users can use the various

  20. Using publicly available internet tools to teach patent research and development

    DEFF Research Database (Denmark)

    Jensen, Søren; Tanev, Stoyan

    2013-01-01

    the university curriculum with appropriately designed courses focusing on patent development strategies. There is therefore a need for the development of such academic courses by using publicly available resources and by focusing on cost efficiency. The focus on the balance between cost and educational...... in more education on the patent system [1]. In this paper we will examine the current literature addressing the subject of teaching patent development to engineering students and entrepreneurs. The review will primarily focus on literature that supports the teaching of patents to engineering students....... With the advancement of the internet a number of patent offices are offering online tools that can be utilized in the teaching of the patent system, we will provide a review and analysis of these tools resulting in a suggestion for a patent course syllabus corresponding to an average student workload of 5 ECTS....

  1. Twitter as a Potential Disaster Risk Reduction Tool. Part I: Introduction, Terminology, Research and Operational Applications.

    Science.gov (United States)

    Cooper, Guy Paul; Yeager, Violet; Burkle, Frederick M; Subbarao, Italo

    2015-06-29

    Twitter, a popular communications platform, is identified as contributing to improved mortality and morbidity outcomes resulting from the 2013 Hattiesburg, Mississippi EF-4 Tornado. This study describes the methodology by which Twitter was investigated as a potential disaster risk reduction and management tool at the community level and the process by which the at-risk population was identified from the broader Twitter user population. By understanding how various factors contribute to the superspreading of messages, one can better optimize Twitter as an essential communications and risk reduction tool. This study introduces Parts II, III and IV which further define the technological and scientific knowledge base necessary for developing future competency base curriculum and content for Twitter assisted disaster management education and training at the community level.

  2. Graphical surface-vegetation-atmosphere transfer (SVAT) model as a pedagogical and research tool

    OpenAIRE

    Gillies, Robert R.; Carlson, Toby N.; Ripley, David A.J.

    1998-01-01

    This paper considers, by example, the use of a Surface-Atmosphere-Vegetation-Transfer (SVAT), Atmospheric Boundary Layer (ABL) model designed as a pedagogical tool. The goal of the computer software and the approach is to improve the efficiency and effectiveness of communicating often complex and mathematical based disciplines (e.g., micrometeorology, land surface processes) to the non-specialist interested in studying problems involving interactions between vegetation and the atmosphere and,...

  3. Citation Index: an indispensable information retrieval tool for research and evaluation

    OpenAIRE

    Kademani, B. S.; Vijai Kumar, *

    2002-01-01

    This paper highlights the information explosion, the need for bibliographic control, the need for information retrieval tools. Explains the emergence of Citation Index, concept of citation indexing, reasons for citing, its structure (print and electronic versions of Science citation Index and Social Science Citation Index ), and application of citation index. It also discusses the search effectiveness, factors taken into consideration for coverage of journals in citation indexes, Journal Cita...

  4. Calculated Parameters of Thyroid Homeostasis: Emerging Tools for Differential Diagnosis and Clinical Research.

    Science.gov (United States)

    Dietrich, Johannes W; Landgrafe-Mende, Gabi; Wiora, Evelin; Chatzitomaris, Apostolos; Klein, Harald H; Midgley, John E M; Hoermann, Rudolf

    2016-01-01

    Although technical problems of thyroid testing have largely been resolved by modern assay technology, biological variation remains a challenge. This applies to subclinical thyroid disease, non-thyroidal illness syndrome, and those 10% of hypothyroid patients, who report impaired quality of life, despite normal thyrotropin (TSH) concentrations under levothyroxine (L-T4) replacement. Among multiple explanations for this condition, inadequate treatment dosage and monotherapy with L-T4 in subjects with impaired deiodination have received major attention. Translation to clinical practice is difficult, however, since univariate reference ranges for TSH and thyroid hormones fail to deliver robust decision algorithms for therapeutic interventions in patients with more subtle thyroid dysfunctions. Advances in mathematical and simulative modeling of pituitary-thyroid feedback control have improved our understanding of physiological mechanisms governing the homeostatic behavior. From multiple cybernetic models developed since 1956, four examples have also been translated to applications in medical decision-making and clinical trials. Structure parameters representing fundamental properties of the processing structure include the calculated secretory capacity of the thyroid gland (SPINA-GT), sum activity of peripheral deiodinases (SPINA-GD) and Jostel's TSH index for assessment of thyrotropic pituitary function, supplemented by a recently published algorithm for reconstructing the personal set point of thyroid homeostasis. In addition, a family of integrated models (University of California-Los Angeles platform) provides advanced methods for bioequivalence studies. This perspective article delivers an overview of current clinical research on the basis of mathematical thyroid models. In addition to a summary of large clinical trials, it provides previously unpublished results of validation studies based on simulation and clinical samples.

  5. Depicting community perspectives: repeat photography and participatory research as tools for assessing environmental services in Sagarmatha National Park, Nepal

    OpenAIRE

    Rodney Garrard; Thomas Kohler; Urs Wiesmann; Martin F. Price; Alton C. Byers; Ang Rita Sherp

    2015-01-01

    Efforts have been made to provide a scientific basis for using environmental services as a conceptual tool to enhance conservation and improve livelihoods in protected mountain areas (MtPAS). Little attention has been paid to participatory research or locals’ concerns as environmental service (ES) users and providers. Such perspectives can illuminate the complex interplay between mountain ecosystems, environmental services and the determinants of human well-being. Repeat photography, long use...

  6. Fish as research tools: alternatives to in vivo experiments

    OpenAIRE

    Schaeck, M.; Van den Broeck, W.; Hermans, K.; Decostere, A.

    2013-01-01

    The use of fish in scientific research is increasing worldwide, due to both the rapid expansion of the fish farming industry and growing awareness of questions concerning the humane use of mammalian models in basic research and chemical testing. As fish are lower on the evolutionary scale than mammals, they are considered to be less sentient. Fish models are providing researchers, and those concerned with animal welfare, with opportunities for adhering to the Three Rs principles of refinement...

  7. Premier Tools of Energy Research Also Probe Secrets of Viral Disease

    Science.gov (United States)

    Chui, Glennda

    2011-03-28

    Advanced light sources peer into matter at the atomic and molecular scales, with applications ranging from physics, chemistry, materials science, and advanced energy research, to biology and medicine.

  8. A new tool for converting food frequency questionnaire data into nutrient and food group values: FETA research methods and availability.

    Science.gov (United States)

    Mulligan, Angela A; Luben, Robert N; Bhaniani, Amit; Parry-Smith, David J; O'Connor, Laura; Khawaja, Anthony P; Forouhi, Nita G; Khaw, Kay-Tee

    2014-03-27

    To describe the research methods for the development of a new open source, cross-platform tool which processes data from the European Prospective Investigation into Cancer and Nutrition Norfolk Food Frequency Questionnaire (EPIC-Norfolk FFQ). A further aim was to compare nutrient and food group values derived from the current tool (FETA, FFQ EPIC Tool for Analysis) with the previously validated but less accessible tool, CAFÉ (Compositional Analyses from Frequency Estimates). The effect of text matching on intake data was also investigated. Cross-sectional analysis of a prospective cohort study-EPIC-Norfolk. East England population (city of Norwich and its surrounding small towns and rural areas). Complete FFQ data from 11 250 men and 13 602 women (mean age 59 years; range 40-79 years). Nutrient and food group intakes derived from FETA and CAFÉ analyses of EPIC-Norfolk FFQ data. Nutrient outputs from FETA and CAFÉ were similar; mean (SD) energy intake from FETA was 9222 kJ (2633) in men, 8113 kJ (2296) in women, compared with CAFÉ intakes of 9175 kJ (2630) in men, 8091 kJ (2298) in women. The majority of differences resulted in one or less quintile change (98.7%). Only mean daily fruit and vegetable food group intakes were higher in women than in men (278 vs 212 and 284 vs 255 g, respectively). Quintile changes were evident for all nutrients, with the exception of alcohol, when text matching was not executed; however, only the cereals food group was affected. FETA produces similar nutrient and food group values to the previously validated CAFÉ but has the advantages of being open source, cross-platform and complete with a data-entry form directly compatible with the software. The tool will facilitate research using the EPIC-Norfolk FFQ, and can be customised for different study populations.

  9. Application of the enterprise management tools Lean Six Sigma and PMBOK in developing a program of research management.

    Science.gov (United States)

    Hors, Cora; Goldberg, Anna Carla; Almeida, Ederson Haroldo Pereira de; Babio Júnior, Fernando Galan; Rizzo, Luiz Vicente

    2012-01-01

    Introduce a program for the management of scientific research in a General Hospital employing the business management tools Lean Six Sigma and PMBOK for project management in this area. The Lean Six Sigma methodology was used to improve the management of the institution's scientific research through a specific tool (DMAIC) for identification, implementation and posterior analysis based on PMBOK practices of the solutions found. We present our solutions for the management of institutional research projects at the Sociedade Beneficente Israelita Brasileira Albert Einstein. The solutions were classified into four headings: people, processes, systems and organizational culture. A preliminary analysis of these solutions showed them to be completely or partially compliant to the processes described in the PMBOK Guide. In this post facto study, we verified that the solutions drawn from a project using Lean Six Sigma methodology and based on PMBOK enabled the improvement of our processes dealing with the management of scientific research carried out in the institution and constitutes a model to contribute to the search of innovative science management solutions by other institutions dealing with scientific research in Brazil.

  10. Research on Error Modelling and Identification of 3 Axis NC Machine Tools Based on Cross Grid Encoder Measurement

    International Nuclear Information System (INIS)

    Du, Z C; Lv, C F; Hong, M S

    2006-01-01

    A new error modelling and identification method based on the cross grid encoder is proposed in this paper. Generally, there are 21 error components in the geometric error of the 3 axis NC machine tools. However according our theoretical analysis, the squareness error among different guide ways affects not only the translation error component, but also the rotational ones. Therefore, a revised synthetic error model is developed. And the mapping relationship between the error component and radial motion error of round workpiece manufactured on the NC machine tools are deduced. This mapping relationship shows that the radial error of circular motion is the comprehensive function result of all the error components of link, worktable, sliding table and main spindle block. Aiming to overcome the solution singularity shortcoming of traditional error component identification method, a new multi-step identification method of error component by using the Cross Grid Encoder measurement technology is proposed based on the kinematic error model of NC machine tool. Firstly, the 12 translational error components of the NC machine tool are measured and identified by using the least square method (LSM) when the NC machine tools go linear motion in the three orthogonal planes: XOY plane, XOZ plane and YOZ plane. Secondly, the circular error tracks are measured when the NC machine tools go circular motion in the same above orthogonal planes by using the cross grid encoder Heidenhain KGM 182. Therefore 9 rotational errors can be identified by using LSM. Finally the experimental validation of the above modelling theory and identification method is carried out in the 3 axis CNC vertical machining centre Cincinnati 750 Arrow. The entire 21 error components have been successfully measured out by the above method. Research shows the multi-step modelling and identification method is very suitable for 'on machine measurement'

  11. Narrative health research: Exploring big and small stories as analytical tools

    NARCIS (Netherlands)

    Sools, Anna Maria

    2013-01-01

    In qualitative health research many researchers use a narrative approach to study lay health concepts and experiences. In this article, I explore the theoretical linkages between the concepts narrative and health, which are used in a variety of ways. The article builds on previous work that

  12. OPERATIONS-RESEARCH AS A TOOL FOR ANALYSIS OF FOOD SECURITY PROBLEMS

    NARCIS (Netherlands)

    SCHWEIGMAN, C; BAKKER, EJ; SNIJDERS, TAB

    1990-01-01

    In the first part of the paper the role of operations research in analyzing daily life problems of farmers in developing countries is discussed. Experiences on village studies in Tanzania are reported which formed part of the training in operations research of students of the University of Dar es

  13. Qualitative Network Analysis Tools for the Configurative Articulation of Cultural Value and Impact from Research

    Science.gov (United States)

    Oancea, Alis; Florez Petour, Teresa; Atkinson, Jeanette

    2017-01-01

    This article introduces a methodological approach for articulating and communicating the impact and value of research: qualitative network analysis using collaborative configuration tracing and visualization. The approach was proposed initially in Oancea ("Interpretations and Practices of Research Impact across the Range of Disciplines…

  14. Action Research: A Tool for Promoting Faculty Development and Continuous Improvement in Leadership Preparation

    Science.gov (United States)

    Carver, Cynthia L.; Klein, C. Suzanne

    2013-01-01

    This paper introduces the use of action research to examine the content and outcomes of university-based leadership preparation programs. Using examples drawn from an ongoing action research project with candidates in a master's level principal preparation program, we demonstrate how the collection and analysis of candidate's written reflections,…

  15. Microcomputers versus Mainframe Computers: Selecting the Appropriate Computing Tool in Institutional Research.

    Science.gov (United States)

    Mannering, Linda W.; McKinney, Richard L.

    The paper sets the stage for the effective and efficient use of computers in institutional research. The microcomputer and the mainframe computer are contrasted for those researchers who have a choice of where to process data. General computer use, specific microcomputer and mainframe computing guidelines, and an application utilizing both…

  16. Using Twitter for Demographic and Social Science Research: Tools for Data Collection and Processing

    Science.gov (United States)

    McCormick, Tyler H.; Lee, Hedwig; Cesare, Nina; Shojaie, Ali; Spiro, Emma S.

    2017-01-01

    Despite recent and growing interest in using Twitter to examine human behavior and attitudes, there is still significant room for growth regarding the ability to leverage Twitter data for social science research. In particular, gleaning demographic information about Twitter users--a key component of much social science research--remains a…

  17. A Microsoft Excel interface for rhyolite-MELTS: a tool for research and teaching of magma properties and evolution

    Science.gov (United States)

    Gualda, G. A.; Ghiorso, M. S.

    2013-12-01

    The thermodynamic modeling software MELTS (and its derivatives) is a powerful and much utilized tool for investigating crystallization and melting in natural magmatic systems. Rhyolite-MELTS (Gualda et al. 2012, J. Petrol. 53:875-890) is a recent recalibration of MELTS aimed at better capturing the evolution of magmas present in the upper crust (up to ~400 MPa pressure). Currently, most users of rhyolite-MELTS rely on a graphical user interface (GUI), which can be run on UNIX/LINUX and Mac OS X computers. While the interface is powerful and flexible, it can be somewhat cumbersome for the novice and the output is in the form of text files that need to be processed offline. This situation is probably the main reason why MELTS - despite great potential - has not been used more frequently for teaching purposes. We are currently developing an alternative GUI for rhyolite-MELTS using web services consumed by a VBA backend in Microsoft Excel©. The goal is to create a much more interactive tool, that is easy to use that can be made available to a widespread audience, and that will be useful for both research and teaching. The interface is contained within a macro-enabled workbook, which includes editable cells where the user can insert the model input information. Interface buttons initiate computations that are executed on a central server at OFM Research in Seattle (WA). Results of simple calculations are shown immediately within the interface itself. For instance, a user can very rapidly determine the temperature at which a magma of a given composition is completely molten (i.e. find the liquidus); or determine which phases are present, in what abundances, their compositions, and their physical properties (e.g. density, viscosity) at any given combination of temperature, pressure and oxygen fugacity. We expect that using the interface in this mode will greatly facilitate building intuition about magmas and their properties. It is also possible to combine a sequence of

  18. Design of a mobile aerosol research laboratory and data processing tools for effective stationary and mobile field measurements

    Directory of Open Access Journals (Sweden)

    F. Drewnick

    2012-06-01

    Full Text Available A compact mobile aerosol research laboratory (MoLa for stationary and mobile measurements of aerosol and trace gas characteristics was developed at the Max Planck Institute for Chemistry (MPIC in Mainz, Germany. Major efforts were made to design an aerosol inlet system which is optimized and characterised for both, stationary and mobile measurements using a particle loss modelling approach. The instrumentation on board allows the determination of a multitude of physical and chemical aerosol parameters, for example particle number and mass concentration (PM1/2.5/10, particle size distributions in the diameter range 6 nm up to 32 μm, and chemical composition of the sub-micron aerosol. Furthermore, trace gas concentrations of O3, SO2, CO, CO2, NO, NO2 and water vapour as well as meteorological parameters like temperature, relative humidity, pressure, wind, solar radiation and precipitation are measured together with various housekeeping parameters. All instruments collect data with high time resolution in the second to minute-range. The measurement platform, as well as data acquisition and handling tools, are optimized for efficient application to various measurement settings. The mobile laboratory is designed to be used for mobile investigation of anthropogenically influenced environments. Possible applications include pollutant mapping, chasing of mobile sources or Lagrangian-type measurements in emission plumes, but also stationary measurements with possible frequent position changes and a well-characterised instrument setup. In addition to the design and features of the mobile laboratory, its inlet system and instrumentation as well as examples of applications of this platform are presented. Challenges associated with such measurements and approaches to extract the desired information from the mobile datasets are discussed.

  19. Using the open Web as an information resource and scholarly Web search engines as retrieval tools for academic and research purposes

    Directory of Open Access Journals (Sweden)

    Filistea Naude

    2010-12-01

    Full Text Available This study provided insight into the significance of the open Web as an information resource and Web search engines as research tools amongst academics. The academic staff establishment of the University of South Africa (Unisa was invited to participate in a questionnaire survey and included 1188 staff members from five colleges. This study culminated in a PhD dissertation in 2008. One hundred and eighty seven respondents participated in the survey which gave a response rate of 15.7%. The results of this study show that academics have indeed accepted the open Web as a useful information resource and Web search engines as retrieval tools when seeking information for academic and research work. The majority of respondents used the open Web and Web search engines on a daily or weekly basis to source academic and research information. The main obstacles presented by using the open Web and Web search engines included lack of time to search and browse the Web, information overload, poor network speed and the slow downloading speed of webpages.

  20. Using the open Web as an information resource and scholarly Web search engines as retrieval tools for academic and research purposes

    Directory of Open Access Journals (Sweden)

    Filistea Naude

    2010-08-01

    Full Text Available This study provided insight into the significance of the open Web as an information resource and Web search engines as research tools amongst academics. The academic staff establishment of the University of South Africa (Unisa was invited to participate in a questionnaire survey and included 1188 staff members from five colleges. This study culminated in a PhD dissertation in 2008. One hundred and eighty seven respondents participated in the survey which gave a response rate of 15.7%. The results of this study show that academics have indeed accepted the open Web as a useful information resource and Web search engines as retrieval tools when seeking information for academic and research work. The majority of respondents used the open Web and Web search engines on a daily or weekly basis to source academic and research information. The main obstacles presented by using the open Web and Web search engines included lack of time to search and browse the Web, information overload, poor network speed and the slow downloading speed of webpages.