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  1. Risk of labor dystocia increases with maternal age irrespective of parity: a population-based register study.

    Science.gov (United States)

    Waldenström, Ulla; Ekéus, Cecilia

    2017-09-01

    Advanced maternal age is associated with labor dystocia (LD) in nulliparous women. This study investigates the age-related risk of LD in first, second and third births. All live singleton cephalic births at term (≥ 37 gestational weeks) recorded in the Swedish Medical Birth Register from 1999 to 2011, except elective cesarean sections and fourth births and more, in total 998 675 pregnancies, were included in the study. LD was defined by International Classification of Diseases, version 10 codes (O620, O621, O622, O629, O630, O631 and O639). In each parity group risks of LD at age 25-29 years, 30-34 years, 35-39 years and ≥ 40 years compared with age < 25 years were investigated by logistic regression analyses. Analyses were adjusted for year of delivery, education, country/region of birth, smoking in early pregnancy, maternal height, body mass index, week of gestation, fetal presentation and infant birthweight. Rates of LD were 22.5%, 6.1% and 4% in first, second and third births, respectively. Adjusted odd ratios (OR) for LD increased progressively from the youngest to the oldest age group, irrespective of parity. At age 35-39 years the adjusted OR (95% CI) was approximately doubled compared with age 25 and younger: 2.13 (2.06-2.20) in first birth; 2.05 (1.91-2.19) in second births; and 1.81 (1.49-2.21) in third births. Maternal age is an independent risk factor for LD in first, second and third births. Although age-related risks by parity are relatively similar, more nulliparous than parous women will be exposed to LD due to the higher rate. © 2017 Nordic Federation of Societies of Obstetrics and Gynecology.

  2. Alcohol use disorders increase the risk of completed suicide - Irrespective of other psychiatric disorders. A longitudinal cohort study

    DEFF Research Database (Denmark)

    Flensborg-Madsen, Trine; Knop, Joachim; Mortensen, Erik Lykke

    2009-01-01

    suicide, AUD, Psychotic disorders, Anxiety disorders, Mood disorders, Personality disorders, Drug abuse, and Other psychiatric disorders. Individuals registered with AUD were at significantly increased risk of committing suicide, with a crude hazard ratio (HR) of 7.98 [Confidence interval (CI): 5......Knowledge of the epidemiology of suicide is a necessary prerequisite for developing prevention programs. The aim of this study was to analyze the risk of completed suicide among individuals with alcohol use disorders (AUD), and to assess the role of other psychiatric disorders in this association.......27-12.07] compared to individuals without AUD. Adjusting for all psychiatric disorders the risk fell to 3.23 (CI: 1.96-5.33). In the stratified sub-sample of individuals without psychiatric disorders, the risk of completed suicide was 9.69 (CI: 4.88-19.25) among individuals with AUD. The results indicate...

  3. Primary early correction of tetralogy of Fallot irrespective of age.

    Science.gov (United States)

    Kantorova, Andrea; Zbieranek, Kai; Sauer, Henning; Lilje, Christian; Haun, Christoph; Hraska, Viktor

    2008-04-01

    The policy of early repair of patients with tetralogy of Fallot, irrespective of age, as opposed to initial palliation with a shunt, remains controversial. The aim of our study was to analyze the midterm outcome of primary early correction of tetralogy of Fallot. Between 1996 and 2005, a total of 61 consecutive patients less than 6 months of age underwent primary correction of tetralogy of Fallot in two institutions. The median age at surgery was 3.3 months, and 27 patients (44%) were younger than 3 months of age, including 12 (20%) newborns. We analyzed the patients in 2 groups: those younger than 3 months of age, and those aged between 3 and 6 months. There was one early (1.6%), and one late death. Actuarial survival was 98.4%, 96.7%, 96.7% at 1, 5, and 10 years respectively, with a median follow up of 4.5 years. There was no difference in survival, bypass time, lengths of ventilation, and hospital stay between the groups. A transjunctional patch was placed significantly more often in the patients younger than 3 months (p = 0.039), with no adverse effect on survival and morbidity during the follow-up. Freedom from reoperation was 98.2%, 92.2%, and 83% at 1, 5, and 10 years respectively, with no difference between the groups. Elective primary repair of tetralogy of Fallot in asymptomatic patients is delayed beyond 3 months of age. In symptomatic patients, primary repair of tetralogy of Fallot is performed irrespective of age, weight and preoperative state. This approach is safe, and provides an excellent midterm outcome with acceptable morbidity and rates of reintervention. The long-term benefits of this approach must be established by careful follow-up, with particular emphasis on arrhythmias, right ventricular function, and exercise performance.

  4. Current Research Studies

    Science.gov (United States)

    ... Success Home > Explore Research > Current Research Studies Current Research Studies Email Print + Share The Crohn’s & Colitis Foundation ... conducted online. Learn more about IBD Partners. Clinical Research Alliance The Clinical Research Alliance is a network ...

  5. Case Study Research Methodology

    Directory of Open Access Journals (Sweden)

    Mark Widdowson

    2011-01-01

    Full Text Available Commenting on the lack of case studies published in modern psychotherapy publications, the author reviews the strengths of case study methodology and responds to common criticisms, before providing a summary of types of case studies including clinical, experimental and naturalistic. Suggestions are included for developing systematic case studies and brief descriptions are given of a range of research resources relating to outcome and process measures. Examples of a pragmatic case study design and a hermeneutic single-case efficacy design are given and the paper concludes with some ethical considerations and an exhortation to the TA community to engage more widely in case study research.

  6. Accelerator research studies

    International Nuclear Information System (INIS)

    1990-01-01

    This progress report for the Accelerator Research Studies program at the University of Maryland covers the second year (June 1, 1989 to May 31, 1990) of the current three-year contract period from June 1, 1988 to May 31, 1991, funded by the Department of Energy under Contract No. AC05-85ER40216. The research program is divided into three separate tasks, as follows: the study of Transport and Longitudinal Compression of Intense, High-Brightness Beams; the study of Collective Ion Acceleration by Intense Electron Beams and Pulse-Powered Plasma Focus; the study of Microwave Sources and Parameter Scaling for High-Frequency Linacs. This report consists of three sections in which the progress for each task is documented separately. An introduction and synopsis is presented at the beginning of the progress report for each task

  7. Objectivist case study research

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Fachner, Jörg

    2016-01-01

    be achieved through the use of objectivist case study research. The strength of the case study design is that it allows for uncovering or suggesting causal relationships in real-life settings through an intensive and rich collection of data. According to Hilliard (1993), the opposite applies for extensive......In order to comprehend the impact of music therapy or music therapy processes, a researcher might look for an approach where the topic under investigation can be understood within a broader context. This calls for a rich inclusion of data and consequently a limited number of participants and may...... designs, in which a small amount of data is gathered on a large number of subjects. With the richness of data, the intensive design is ―the primary pragmatic reason for engaging in single-case or small N research‖ (p. 374) and for working from an idiographic rather than a nomothetic perspective....

  8. Case Study Research Methodology in Nursing Research.

    Science.gov (United States)

    Cope, Diane G

    2015-11-01

    Through data collection methods using a holistic approach that focuses on variables in a natural setting, qualitative research methods seek to understand participants' perceptions and interpretations. Common qualitative research methods include ethnography, phenomenology, grounded theory, and historic research. Another type of methodology that has a similar qualitative approach is case study research, which seeks to understand a phenomenon or case from multiple perspectives within a given real-world context.

  9. Accelerator research studies

    International Nuclear Information System (INIS)

    1993-01-01

    The Accelerator Research Studies program at the University of Maryland, sponsored by the Department of Energy under grant number DE-FG05-91ER40642, is currently in the second year of a three-year funding cycle. The program consists of the following three tasks: TASK A, ''Study of Transport and Longitudinal Compression of Intense, High-Brightness Beams,'' (P.I., M. Reiser); TASK B, ''Study of Collective Ion Acceleration by Intense Electron Beams and Pseudospark Produced High Brightness Electron Beams,'' (Co-P.I.'s, W.W. Destler, M. Reiser, M.J. Rhee, and C.D. Striffler); TASK C, ''Study of a Gyroklystron High-Power Microwave Source for Linear Colliders,'' (Co-P.I.'s, V.L. Granatstein, W. Lawson, M. Reiser, and C.D. Striffler). In this report we document the progress that has been made during the past year for each of the three tasks

  10. Accelerator research studies

    International Nuclear Information System (INIS)

    1992-01-01

    The Accelerator Research Studies program at the University of Maryland, sponsored by the Department of Energy under grant number DE-FG05-91ER40642, is currently in the first year of a three-year funding cycle. The program consists of the following three tasks: TASK A, Study of Transport and Longitudinal Compression of Intense, High-Brightness Beams, TASK B, Study of Collective Ion Acceleration by Intense Electron Beams and Pseudospark Produced High Brightness Electron Beams; TASK C, Study of a Gyroklystron High-power Microwave Source for Linear Colliders. In this report we document the progress that has been made during the past year for each of the three tasks

  11. Human Adult Stem Cells Maintain a Constant Phenotype Profile Irrespective of Their Origin, Basal Media, and Long Term Cultures

    Directory of Open Access Journals (Sweden)

    Indumathi Somasundaram

    2015-01-01

    Full Text Available The study aims to identify the phenotypic marker expressions of different human adult stem cells derived from, namely, bone marrow, subcutaneous fat, and omentum fat, cultured in different media, namely, DMEM-Low Glucose, Alpha-MEM, DMEM-F12 and DMEM-KO and under long term culture conditions (>P20. We characterized immunophenotype by using various hematopoietic, mesenchymal, endothelial markers, and cell adhesion molecules in the long term cultures (Passages-P1, P3, P5, P9, P12, P15, and P20. Interestingly, data revealed similar marker expression profiles irrespective of source, basal media, and extensive culturing. This demonstrates that all adult stem cell sources mentioned in this study share similar phenotypic marker and all media seem appropriate for culturing these sources. However, a disparity was observed in the markers such as CD49d, CD54, CD117, CD29, and CD106, thereby warranting further research on these markers. Besides the aforesaid objective, it is understood from the study that immunophenotyping acts as a valuable tool to identify inherent property of each cell, thereby leading to a valuable cell based therapy.

  12. Australian research reactor studies

    International Nuclear Information System (INIS)

    McCulloch, D.B.

    1978-01-01

    The Australian AEC has two research reactors at the Lucas Heights Research Establishment, a 10 HW DIDO class materials testing reactor, HIFAR, and a smaller 100kW reactor MOATA, which was recently upgraded from 10kW power level. Because of the HIFAR being some 20 years old, major renewal and repair programmes are necessary to keep it operational. To enable meeting projected increases in demand for radioisotopes, plans for a new reactor to replace the HIFAR have been made and the design criteria are described in the paper. (author)

  13. Neural network and SVM classifiers accurately predict lipid binding proteins, irrespective of sequence homology.

    Science.gov (United States)

    Bakhtiarizadeh, Mohammad Reza; Moradi-Shahrbabak, Mohammad; Ebrahimi, Mansour; Ebrahimie, Esmaeil

    2014-09-07

    Due to the central roles of lipid binding proteins (LBPs) in many biological processes, sequence based identification of LBPs is of great interest. The major challenge is that LBPs are diverse in sequence, structure, and function which results in low accuracy of sequence homology based methods. Therefore, there is a need for developing alternative functional prediction methods irrespective of sequence similarity. To identify LBPs from non-LBPs, the performances of support vector machine (SVM) and neural network were compared in this study. Comprehensive protein features and various techniques were employed to create datasets. Five-fold cross-validation (CV) and independent evaluation (IE) tests were used to assess the validity of the two methods. The results indicated that SVM outperforms neural network. SVM achieved 89.28% (CV) and 89.55% (IE) overall accuracy in identification of LBPs from non-LBPs and 92.06% (CV) and 92.90% (IE) (in average) for classification of different LBPs classes. Increasing the number and the range of extracted protein features as well as optimization of the SVM parameters significantly increased the efficiency of LBPs class prediction in comparison to the only previous report in this field. Altogether, the results showed that the SVM algorithm can be run on broad, computationally calculated protein features and offers a promising tool in detection of LBPs classes. The proposed approach has the potential to integrate and improve the common sequence alignment based methods. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. Oxidized LDL Is Strictly Limited to Hyperthyroidism Irrespective of Fat Feeding in Female Sprague Dawley Rats

    Directory of Open Access Journals (Sweden)

    Sieglinde Zelzer

    2015-05-01

    Full Text Available Metabolic dysfunctions might play a crucial role in the pathophysiology of thyroid dysfunctions. This study aimed to investigate the impact of a controlled diet (normal versus high fat feeding on hypothyroid and hyperthyroid Sprague Dawley rats. Female Sprague Dawley rats (n = 66 were grouped into normal diet (n = 30 and high-fat diet (n = 36 groups and subdivided into controls, hypothyroid and hyperthyroid groups, induced through propylthiouracil or triiodothyronine (T3 treatment, respectively. After 12 weeks of treatment metabolic parameters, such as oxidized LDL (oxLDL, malondialdehyde (MDA, 4-hydroxynonenal (HNE, the lipid profile, body weight and food intake parameters were analyzed. Successfully induced thyroid dysfunctions were shown by T3 levels, both under normal and high fat diet. Thyroid dysfunctions were accompanied by changes in calorie intake and body weight as well as in the lipid profile. In detail, hypothyroid rats showed significantly decreased oxLDL levels, whereas hyperthyroid rats showed significantly increased oxLDL levels. These effects were seen under high fat diet and were less pronounced with normal feeding. Taken together, we showed for the first time in female SD rats that only hyper-, but not hypothyroidism, is associated with high atherogenic oxidized LDL irrespective of normal or high-fat diet in Sprague Dawley rats.

  15. Oxidized LDL Is Strictly Limited to Hyperthyroidism Irrespective of Fat Feeding in Female Sprague Dawley Rats.

    Science.gov (United States)

    Zelzer, Sieglinde; Mangge, Harald; Pailer, Sabine; Ainoedhofer, Herwig; Kieslinger, Petra; Stojakovic, Tatjana; Scharnagl, Hubert; Prüller, Florian; Weghuber, Daniel; Datz, Christian; Haybaeck, Johannes; Obermayer-Pietsch, Barbara; Trummer, Christian; Gostner, Johanna; Gruber, Hans-Jürgen

    2015-05-21

    Metabolic dysfunctions might play a crucial role in the pathophysiology of thyroid dysfunctions. This study aimed to investigate the impact of a controlled diet (normal versus high fat feeding) on hypothyroid and hyperthyroid Sprague Dawley rats. Female Sprague Dawley rats (n = 66) were grouped into normal diet (n = 30) and high-fat diet (n = 36) groups and subdivided into controls, hypothyroid and hyperthyroid groups, induced through propylthiouracil or triiodothyronine (T3) treatment, respectively. After 12 weeks of treatment metabolic parameters, such as oxidized LDL (oxLDL), malondialdehyde (MDA), 4-hydroxynonenal (HNE), the lipid profile, body weight and food intake parameters were analyzed. Successfully induced thyroid dysfunctions were shown by T3 levels, both under normal and high fat diet. Thyroid dysfunctions were accompanied by changes in calorie intake and body weight as well as in the lipid profile. In detail, hypothyroid rats showed significantly decreased oxLDL levels, whereas hyperthyroid rats showed significantly increased oxLDL levels. These effects were seen under high fat diet and were less pronounced with normal feeding. Taken together, we showed for the first time in female SD rats that only hyper-, but not hypothyroidism, is associated with high atherogenic oxidized LDL irrespective of normal or high-fat diet in Sprague Dawley rats.

  16. Applied Research Study

    Science.gov (United States)

    Leach, Ronald J.

    1997-01-01

    The purpose of this project was to study the feasibility of reusing major components of a software system that had been used to control the operations of a spacecraft launched in the 1980s. The study was done in the context of a ground data processing system that was to be rehosted from a large mainframe to an inexpensive workstation. The study concluded that a systematic approach using inexpensive tools could aid in the reengineering process by identifying a set of certified reusable components. The study also developed procedures for determining duplicate versions of software, which were created because of inadequate naming conventions. Such procedures reduced reengineering costs by approximately 19.4 percent.

  17. Unwanted road to anaemia in transthyretin familial amyloid polyneuropathy may continue irrespective of tafamidis treatment.

    Science.gov (United States)

    Ikeda, Tokunori; Masuda, Teruaki; Ueda, Mitsuharu; Yamashita, Taro; Misumi, Yohei; Shinriki, Satoru; Ando, Yukio

    2018-01-01

    Background This retrospective longitudinal study was performed to determine whether tafamidis treatment leads to improvements in commonly used blood data for transthyretin familial amyloid polyneuropathy (TTR-FAP). Methods Commonly used blood data (complete blood count [including a haemogram], total protein, albumin, blood urea nitrogen, creatinine, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, lactate dehydrogenase, γ-glutamyl transpeptidase, total bilirubin [T-Bil], creatine kinase, choline esterase, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, estimated glomerular filtration rate [eGFR], serum amyloid A protein, TTR, haemoglobin A1c, free triiodothyronine [FT3] and free thyroxine [FT4]) were investigated in 33 TTR-FAP patients. These values included longitudinal data at three time points: six months before or after tafamidis treatment and one year after tafamidis treatment. Longitudinal changes in each blood item were examined using a linear mixed model, adjusting for age at starting tafamidis, sex, TTR-FAP stage and value before tafamidis treatment. Results Our results show elevated TTR concentrations after tafamidis treatment. In contrast, haemoglobin, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, mean platelet volume, platelet distribution width, T-Bil, eGFR, FT3 and FT4, gradually decreased through a reference range. There were no characteristic observations in any other items. TTR binds to thyroid hormone; therefore, FT3 and FT4 decreased in inverse proportion to increased TTR concentrations. Conclusion Unfortunately, progression to anaemia may occur regardless of tafamidis treatment. Because anaemia is sometimes present in TTR-FAP, attention should be paid to longitudinal changes in commonly used blood data, irrespective of tafamidis treatment.

  18. Olanzapine is effective for refractory chemotherapy-induced nausea and vomiting irrespective of chemotherapy emetogenicity.

    Science.gov (United States)

    Vig, Sierra; Seibert, Laurel; Green, Myke R

    2014-01-01

    The role of olanzapine added to a dopamine antagonist and benzodiazepine for the treatment of refractory chemotherapy-induced nausea and vomiting (CINV) is incompletely characterized in all levels of chemotherapy emetogenicity. This retrospective study evaluated the efficacy of the addition of olanzapine in adults experiencing refractory CINV stratified by chemotherapy emetogenicity. Thirty-three adults who experienced CINV refractory to guideline-recommended prophylaxis and breakthrough antiemetics (dopamine antagonists and benzodiazepines) and received at least one dose of olanzapine 5-10 mg per os were evaluated. Failure was defined as >5 emesis events in 24 h or more than 10 cumulative doses of rescue antiemetics following first olanzapine dose per treatment cycle. Post hoc analyses investigated variables impacting olanzapine efficacy. The addition of olanzapine demonstrated an overall success rate of 70 %. This success rate did not differ between chemotherapy regimens of high versus low-to-moderate emetogenicity (p = 0.79), prophylaxis with serotonin antagonist plus corticosteroid and aprepitant versus serotonin antagonist alone (p = 0.77), or age over 50 versus ≤50 years (p > 0.99). A trend toward greater benefit was seen in women (p = 0.08). The addition of olanzapine to a dopamine antagonist and benzodiazepine demonstrated high efficacy rates for refractory CINV irrespective of chemotherapy emetogenicity. The high success rates among all groups suggests that incomplete resolution of CINV with prophylactic serotonin antagonists and breakthrough dopamine antagonists plus benzodiazepine may benefit from the addition of olanzapine regardless of gender, degree of chemotherapy emetogenicity, number of prophylactic antiemetics, or age. The trend toward greater control of emesis in women merits further investigation.

  19. Relational Research and Organisation Studies

    DEFF Research Database (Denmark)

    Madsen, Charlotte Øland; Larsen, Mette Vinther; Hansen, Lone Hersted

    , analyzing organizational dialoguing, and polyphonic future-forming ways of writing up research.  Relational Research and Organisation Studies does not only present and discuss guidelines for practice at a onto-epistemological level but also presents and discusses concrete cases of research projects building...... on relational constructionist ideas. Furthermore, excerpts of data are presented and analyzed in order to explain the co-constructed processes of the inquiries more in detail. Relational Research and Organisation Studies invites the reader into the process of planning and carrying out relational constructionist......This volume lays out a variety of ways of engaging in research projects focused on exploring the everyday relational practices of organizing and leading is presented. The main focus is through elaborate examples from the author’s own research to further the understanding of how it is possible...

  20. International Research and Studies Program

    Science.gov (United States)

    Office of Postsecondary Education, US Department of Education, 2012

    2012-01-01

    The International Research and Studies Program supports surveys, studies, and instructional materials development to improve and strengthen instruction in modern foreign languages, area studies, and other international fields. The purpose of the program is to improve and strengthen instruction in modern foreign languages, area studies and other…

  1. Reliability studies in research reactors

    International Nuclear Information System (INIS)

    Albuquerque, Tob Rodrigues de

    2013-01-01

    Fault trees and event trees are widely used in industry to model and to evaluate the reliability of safety systems. Detailed analyzes in nuclear installations require the combination of these two techniques. This study uses the methods of FT (Fault Tree) and ET (Event Tree) to accomplish the PSA (Probabilistic Safety Assessment) in research reactors. According to IAEA (lnternational Atomic Energy Agency), the PSA is divided into Level 1, Level 2 and Level 3. At the Level 1, conceptually, the security systems perform to prevent the occurrence of accidents, At the Level 2, once accidents happened, this Level seeks to minimize consequences, known as stage management of accident, and at Level 3 accident impacts are determined. This study focuses on analyzing the Level 1, and searching through the acquisition of knowledge, the consolidation of methodologies for future reliability studies. The Greek Research Reactor, GRR-1, is a case example. The LOCA (Loss of Coolant Accident) was chosen as the initiating event and from it, using ET, possible accidental sequences were developed, which could lead damage to the core. Moreover, for each of affected systems, probabilities of each event top of FT were developed and evaluated in possible accidental sequences. Also, the estimates of importance measures for basic events are presented in this work. The studies of this research were conducted using a commercial computational tool SAPHIRE. Additionally, achieved results thus were considered satisfactory for the performance or the failure of analyzed systems. (author)

  2. Limited OXPHOS capacity in white adipocytes is a hallmark of obesity in laboratory mice irrespective of the glucose tolerance status

    Directory of Open Access Journals (Sweden)

    Theresa Schöttl

    2015-09-01

    Conclusion: Reduced mitochondrial respiratory capacity in white adipocytes is a hallmark of murine obesity irrespective of the glucose tolerance status. Impaired respiratory capacity in white adipocytes solely is not sufficient for the development of systemic glucose intolerance.

  3. Accelerator research studies. Progress report

    International Nuclear Information System (INIS)

    1984-06-01

    Progress is reported in both experimental studies as well as theoretical understanding of the beam transport problem. Major highlights are: (a) the completion of the first channel section with 12 periods and two matching solenoids, (b) measurements of beam transmission and emittance in this 12-lens channel, (c) extensive analytical and numerical studies of the beam transport problem in collaboration with GSI (W. Germany), (d) detailed measurements and calculations of beam propagation through one lens with spherical aberration and space charge, and (e) completion of the emittance grids at the Rutherford-Appleton Laboratory. Our main objectives in Task B of our research program are: (a) study of collective acceleration of positive ions from a localized plasma source by an intense relativistic electron beam (IREB), (b) external control of the IREB beam front by a slow-wave structure to achieve higher ion energies - the Beam Front Accelerator (BFA) concept, (c) study of ion and electron acceleration and other applications of a plasma focus device, and (d) theoretical studies in support of (a) and (b). Our research in these areas has been oriented towards obtaining an improved understanding of the physical processes at work in these experiments and, subsequently, achieving improved performance for specific potential applications

  4. Consumers’ versatile buying behavior irrespective to high and low involvement products

    OpenAIRE

    Hasan, Syed Akif; Subhani, Muhammad Imtiaz; Osman, Ms. Amber

    2012-01-01

    The consumers of today are impulse and cautious buyers at the same time. This study basically comprehends the concept of non-linearity towards the consumer purchase behavior for either high or low involvement of products. The research was interesting to note the consumption patterns of different product classes. The peculiarity of this study found the same non-linearity wavelengths between the high and low involvement products’ that was shaped by the consumers buying intention and actions. AD...

  5. Communicating Qualitative Research Study Designs to Research Ethics Review Boards

    Science.gov (United States)

    Ells, Carolyn

    2011-01-01

    Researchers using qualitative methodologies appear to be particularly prone to having their study designs called into question by research ethics or funding agency review committees. In this paper, the author considers the issue of communicating qualitative research study designs in the context of institutional research ethics review and offers…

  6. Positron studies in catalysis research

    International Nuclear Information System (INIS)

    1994-01-01

    During the past eight months, the authors have made progress in several areas relevant to the eventual use of positron techniques in catalysis research. They have come closer to the completion of their positron microscope, and at the same time have performed several studies in their non-microscopic positron spectrometer which should ultimately be applicable to catalysis. The current status of the efforts in each of these areas is summarized in the following sections: Construction of the positron microscope (optical element construction, data collection software, and electronic sub-assemblies); Doppler broadening spectroscopy of metal silicide; Positron lifetime spectroscopy of glassy polymers; and Positron lifetime measurements of pore-sizes in zeolites

  7. A Timoshenko Piezoelectric Beam Finite Element with Consistent Performance Irrespective of Geometric and Material Configurations

    Directory of Open Access Journals (Sweden)

    Litesh N. Sulbhewar

    Full Text Available Abstract The conventional Timoshenko piezoelectric beam finite elements based on First-order Shear Deformation Theory (FSDT do not maintain the accuracy and convergence consistently over the applicable range of material and geometric properties. In these elements, the inaccuracy arises due to the induced potential effects in the transverse direction and inefficiency arises due to the use of independently assumed linear polynomial interpolation of the field variables in the longitudinal direction. In this work, a novel FSDT-based piezoelectric beam finite element is proposed which is devoid of these deficiencies. A variational formulation with consistent through-thickness potential is developed. The governing equilibrium equations are used to derive the coupled field relations. These relations are used to develop a polynomial interpolation scheme which properly accommodates the bending-extension, bending-shear and induced potential couplings to produce accurate results in an efficient manner. It is noteworthy that this consistently accurate and efficient beam finite element uses the same nodal variables as of conventional FSDT formulations available in the literature. Comparison of numerical results proves the consistent accuracy and efficiency of the proposed formulation irrespective of geometric and material configurations, unlike the conventional formulations.

  8. Earlier saccades to task-relevant targets irrespective of relative gain between peripheral and foveal information.

    Science.gov (United States)

    Wolf, Christian; Schütz, Alexander C

    2017-06-01

    Saccades bring objects of interest onto the fovea for high-acuity processing. Saccades to rewarded targets show shorter latencies that correlate negatively with expected motivational value. Shorter latencies are also observed when the saccade target is relevant for a perceptual discrimination task. Here we tested whether saccade preparation is equally influenced by informational value as it is by motivational value. We defined informational value as the probability that information is task-relevant times the ratio between postsaccadic foveal and presaccadic peripheral discriminability. Using a gaze-contingent display, we independently manipulated peripheral and foveal discriminability of the saccade target. Latencies of saccades with perceptual task were reduced by 36 ms in general, but they were not modulated by the information saccades provide (Experiments 1 and 2). However, latencies showed a clear negative linear correlation with the probability that the target is task-relevant (Experiment 3). We replicated that the facilitation by a perceptual task is spatially specific and not due to generally heightened arousal (Experiment 4). Finally, the facilitation only emerged when the perceptual task is in the visual but not in the auditory modality (Experiment 5). Taken together, these results suggest that saccade latencies are not equally modulated by informational value as by motivational value. The facilitation by a perceptual task only arises when task-relevant visual information is foveated, irrespective of whether the foveation is useful or not.

  9. MET signalling in primary colon epithelial cells leads to increased transformation irrespective of aberrant Wnt signalling

    Science.gov (United States)

    Boon, E M J; Kovarikova, M; Derksen, P W B; van der Neut, R

    2005-01-01

    It has been shown that in hereditary and most sporadic colon tumours, components of the Wnt pathway are mutated. The Wnt target MET has been implicated in the development of colon cancer. Here, we show that overexpression of wild-type or a constitutively activated form of MET in colon epithelial cells leads to increased transformation irrespective of Wnt signalling. Fetal human colon epithelial cells without aberrant Wnt signalling were transfected with wild-type or mutated MET constructs. Expression of these constructs leads to increased phosphorylation of MET and its downstream targets PKB and MAPK. Upon stimulation with HGF, the expression of E-cadherin is downregulated in wild-type MET-transfected cells, whereas cells expressing mutated MET show low E-cadherin levels independent of stimulation with ligand. This implies a higher migratory propensity of these cells. Furthermore, fetal human colon epithelial cells expressing the mutated form of MET have colony-forming capacity in soft agar, while cells expressing wild-type MET show an intermediate phenotype. Subcutaneous injection of mutated MET-transfected cells in nude mice leads to the formation of tumours within 12 days in all mice injected. At this time point, mock-transfected cells do not form tumours, while wild-type MET-transfected cells form subcutaneous tumours in one out of five mice. We thus show that MET signalling can lead to increased transformation of colon epithelial cells independent of Wnt signalling and in this way could play an essential role in the onset and progression of colorectal cancer. PMID:15785735

  10. Undergraduate research: a case study

    NARCIS (Netherlands)

    Koppelman, Hermannus; van Dijk, Elisabeth M.A.G.; van der Hoeven, Gerrit

    This paper describes a one semester research course for undergraduates of computing programs. Students formulate a research proposal, conduct research and write a full paper. They present the results at a one-day student conference. On the one hand we offer the students a lot of structure and

  11. Extended-release niacin/laropiprant significantly improves lipid levels in type 2 diabetes mellitus irrespective of baseline glycemic control

    Directory of Open Access Journals (Sweden)

    Bays HE

    2015-02-01

    Full Text Available Harold E Bays,1 Eliot A Brinton,2 Joseph Triscari,3 Erluo Chen,3 Darbie Maccubbin,3 Alexandra A MacLean,3 Kendra L Gibson,3 Rae Ann Ruck,3 Amy O Johnson-Levonas,3 Edward A O’Neill,3 Yale B Mitchel3 1Louisville Metabolic & Atherosclerosis Research Center (L-MARC, Louisville, KY, USA; 2Utah Foundation for Biomedical Research, Salt Lake City, UT, USA; 3Merck & Co, Inc., Whitehouse Station, NJ, USA Background: The degree of glycemic control in patients with type 2 diabetes mellitus (T2DM may alter lipid levels and may alter the efficacy of lipid-modifying agents. Objective: Evaluate the lipid-modifying efficacy of extended-release niacin/laropiprant (ERN/LRPT in subgroups of patients with T2DM with better or poorer glycemic control. Methods: Post hoc analysis of clinical trial data from patients with T2DM who were randomized 4:3 to double-blind ERN/LRPT or placebo (n=796, examining the lipid-modifying effects of ERN/LRPT in patients with glycosylated hemoglobin or fasting plasma glucose levels above and below median baseline levels. Results: At Week 12 of treatment, ERN/LRPT significantly improved low-density lipoprotein cholesterol, high-density lipoprotein cholesterol (HDL-C, non-high-density lipoprotein cholesterol, triglycerides, and lipoprotein (a, compared with placebo, with equal efficacy in patients above or below median baseline glycemic control. Compared with placebo, over 36 weeks of treatment more patients treated with ERN/LRPT had worsening of their diabetes and required intensification of antihyperglycemic medication, irrespective of baseline glycemic control. Incidences of other adverse experiences were generally low in all treatment groups. Conclusion: The lipid-modifying effects of ERN/LRPT are independent of the degree of baseline glycemic control in patients with T2DM (NCT00485758. Keywords: lipid-modifying agents, hyperglycemia, LDL, HDL, triglycerides

  12. Event-related brain potential correlates of words' emotional valence irrespective of arousal and type of task.

    Science.gov (United States)

    Espuny, Javier; Jiménez-Ortega, Laura; Casado, Pilar; Fondevila, Sabela; Muñoz, Francisco; Hernández-Gutiérrez, David; Martín-Loeches, Manuel

    2018-03-23

    Many Event-Related brain Potential (ERP) experiments have explored how the two main dimensions of emotion, arousal and valence, affect linguistic processing. However, the heterogeneity of experimental paradigms and materials has led to mixed results. In the present study, we aim to clarify words' emotional valence effects on ERP when arousal is controlled, and determine whether these effects may vary as a function of the type of task performed. For these purposes, we designed an ERP experiment with the valence of words manipulated, and arousal equated across valences. The participants performed two types of task: in one, they had to read aloud each word, written in black on a white background; in the other, they had to name the color of the ink in which each word was written. The results showed the main effects of valence irrespective of task, and no interaction between valence and task. The most marked effects of valence were in response to negative words, which elicited an Early Posterior Negativity (EPN) and a Late Positive Complex (LPC). Our results suggest that, when arousal is controlled, the cognitive information in negative words triggers a 'negativity bias', these being the only words able to elicit emotion-related ERP modulations. Moreover, these modulations are largely unaffected by the types of task explored here. Copyright © 2018 Elsevier B.V. All rights reserved.

  13. LATE-NIGHT SALIVARY CORTISOL IS UNALTERED IN PATIENTS WITH POLYCYSTIC OVARIAN SYNDROME (PCOS), IRRESPECTIVE OF DISEASE PHENOTYPE, AND IN OBESE WOMEN, IRRESPECTIVE OF THE PRESENCE OF PCOS.

    Science.gov (United States)

    Ozkaya, Hande Mefkure; Keskin, Fatma Ela; Tuten, Abdullah; Korkmaz, Ebru; Oktay, Hulya Zeynep; Kadioglu, Pinar

    2017-09-01

    To determine cutoff values of late-night salivary cortisol (LNSC) using an electrochemiluminescent immunoassay and investigate whether the diagnostic performance of the assay is influenced by the presence of obesity or polycystic ovary syndrome (PCOS). A total of 124 subjects comprising 25 patients with Cushing syndrome (CS), 44 with PCOS (22 nonobese and 22 obese), 21 with constitutional obesity (CO), and 34 healthy subjects (HS) were included in the study. Two consecutive LNSC samples were collected from all participants. The median LNSC levels of patients with CS were significantly higher than LNSC levels of HS, patients with CO, and obese and nonobese patients with PCOS, respectively (P.05 for all). The cutoff values and corresponding sensitivity and specificity were similar between the groups. The comparisons of the area under curve of the first LNSC (0.963; 95% confidence interval [CI], 0.910 to 0.989), second LNSC (0.954; 95% CI, 0.898 to 0.984), and the mean of two consecutive LNSC (mLNSC) values (0.962; 95% CI, 0.909 to 0.989) did not differ significantly (P>.05 for all). A cutoff value for mLNSC of 7.45 nmol/L yielded a sensitivity of 100% and specificity of 87.5% in HS. In conclusion, LNSC is a reliable test with high diagnostic accuracy in both HS and patients with PCOS and obesity. ACTH = adrenocorticotropic hormone AUC = area under the curve BMI = body mass index CO = constitutional obesity CS = Cushing syndrome E2 = estradiol ECLIA = electrochemiluminescent immunoassay FPG = fasting plasma glucose FSH = follicle-stimulating hormone HOMA-IR = homeostasis model assessment of insulin resistance HPA = hypothalamo-pituitary-adrenal HS = healthy subjects IQR = interquartile range LH = luteinizing hormone LNSC = late-night salivary cortisol LR = likelihood ratio mLNSC = mean of two consecutive LNSC samples PCOS = polycystic ovarian syndrome ROC = receiver operating characteristic UFC = urinary free cortisol WHR = waist-to-hip ratio.

  14. Perception of research and predictors of research career: a study ...

    African Journals Online (AJOL)

    Introduction: Acquisition of research experience by medical students is associated with good research pathway at the postgraduate level and also in the pursuit of a research career. Also, it assists the physician to make evidence based decisions in clinical practice. Objectives: Aim of study was to determine the perception of ...

  15. Hyperinsulinemia correlates with low levels of plasma B-type natriuretic peptide in Japanese men irrespective of fat distribution

    Directory of Open Access Journals (Sweden)

    Nakatsuji Hideaki

    2012-03-01

    Full Text Available Abstract Background B-type natriuretic peptide (BNP, a member of the natriuretic peptide family, is a cardiac-derived secretory hormone with natriuretic, diuretic, and vasorelaxant activities. Intraabdominal fat accumulation is associated with atherosclerotic cardiovascular diseases and cardiac dysfunction. Circulating BNP levels are relatively low (within the normal limits in obesity and the metabolic syndrome. However, the relationship between plasma BNP levels and visceral fat accumulation in general population has not been reported. The present study analyzed the relationships between plasma BNP levels and various clinical variables, including insulin, visceral and subcutaneous fat area (VFA and SFA, respectively, in normal Japanese men. Methods The study (Victor-J study subjects were consecutive 500 Japanese male workers, who underwent a health checkup and were measured VFA and SFA by computed tomography. Results Age-adjusted simple linear regression analysis showed that log-BNP correlated positively with HDL-cholesterol, and negatively with VFA, log-immunoreactive insulin (IRI, log-triglyceride, and LDL-cholesterol, but not body mass index or SFA. Stepwise multiple regression analysis identified log-IRI and HDL-cholesterol as significant determinants of log-BNP. Subjects with IRI ≥5.5 μIU/mL had lower plasma BNP levels than those with IRI 2, visceral fat accumulation (VFA, cutoff value 100 cm2 and subcutaneous fat accumulation (SFA, cutoff value 128 cm2. Conclusions Our study showed that hyperinsulinemia correlated with low levels of plasma BNP in general men, irrespective of fat distribution. Trial registration UMIN 000004318.

  16. Design science research as research approach in doctoral studies

    CSIR Research Space (South Africa)

    Kotzé, P

    2015-08-01

    Full Text Available Since the use of design science research (DSR) gained momentum as a research approach in information systems (IS), the adoption of a DSR approach in postgraduate studies became more acceptable. This paper reflects on a study to investigate how a...

  17. The Sense of Agency Is More Sensitive to Manipulations of Outcome than Movement-Related Feedback Irrespective of Sensory Modality.

    Directory of Open Access Journals (Sweden)

    Nicole David

    Full Text Available The sense of agency describes the ability to experience oneself as the agent of one's own actions. Previous studies of the sense of agency manipulated the predicted sensory feedback related either to movement execution or to the movement's outcome, for example by delaying the movement of a virtual hand or the onset of a tone that resulted from a button press. Such temporal sensorimotor discrepancies reduce the sense of agency. It remains unclear whether movement-related feedback is processed differently than outcome-related feedback in terms of agency experience, especially if these types of feedback differ with respect to sensory modality. We employed a mixed-reality setup, in which participants tracked their finger movements by means of a virtual hand. They performed a single tap, which elicited a sound. The temporal contingency between the participants' finger movements and (i the movement of the virtual hand or (ii the expected auditory outcome was systematically varied. In a visual control experiment, the tap elicited a visual outcome. For each feedback type and participant, changes in the sense of agency were quantified using a forced-choice paradigm and the Method of Constant Stimuli. Participants were more sensitive to delays of outcome than to delays of movement execution. This effect was very similar for visual or auditory outcome delays. Our results indicate different contributions of movement- versus outcome-related sensory feedback to the sense of agency, irrespective of the modality of the outcome. We propose that this differential sensitivity reflects the behavioral importance of assessing authorship of the outcome of an action.

  18. The persistence of maternal vitamin D deficiency and insufficiency during pregnancy and lactation irrespective of season and supplementation.

    Science.gov (United States)

    Kramer, Caroline K; Ye, Chang; Swaminathan, Balakumar; Hanley, Anthony J; Connelly, Philip W; Sermer, Mathew; Zinman, Bernard; Retnakaran, Ravi

    2016-05-01

    Pregnancy and lactation comprise a critical window spanning all seasons during which maternal vitamin D status potentially may influence the long-term health of the newborn. Women typically receive calcium/vitamin D supplementation through antenatal vitamins, but there has been limited serial evaluation of maternal vitamin D status across this critical window. In this prospective observational cohort study, 467 women in Toronto, Canada, underwent measurement of serum 25-hydroxy vitamin D (25-OH-D) at mean 29·7 ± 2·9 weeks' gestation, 3 months postpartum and 12 months postpartum, enabling serial assessment across 3 seasons. At each assessment, vitamin D status was classified as deficiency (25-OH-Dl), insufficiency (25-OH-D≥50 nmol/l and l) or sufficiency (25-OH-D≥75 nmol/l). The prevalence rates of vitamin D deficiency and insufficiency were 31·5% and 35·1% in pregnancy, 33·4% and 35·3% at 3 months, and 35·6% and 33·8% at 12 months postpartum, respectively. These high rates remained stable over time (P = 0·49) despite declining usage of antenatal calcium/vitamin D supplementation from pregnancy to 3 months to 12 months postpartum (P vitamin D deficiency and insufficiency in pregnancy were independently associated with decrements in average 25-OH-D over time of 49·6 nmol/l and 26·4 nmol/l, respectively (both P vitamin D supplements were independently associated with changes in 25-OH-D in the range of 3-5 nmol/l (both P vitamin D deficiency/insufficiency during pregnancy and lactation, irrespective of season and supplementation, supports the emerging concept that current vitamin D supplementation in antenatal care is likely inadequate. © 2015 John Wiley & Sons Ltd.

  19. Researching the Study Abroad Experience

    Science.gov (United States)

    McLeod, Mark; Wainwright, Philip

    2009-01-01

    The authors propose a paradigm for rigorous scientific assessment of study abroad programs, with the focus being on how study abroad experiences affect psychological constructs as opposed to looking solely at study-abroad-related outcomes. Social learning theory is used as a possible theoretical basis for making testable hypotheses and guiding…

  20. Atypical sensory profiles as core features of adult ADHD, irrespective of autistic symptoms.

    Science.gov (United States)

    Bijlenga, D; Tjon-Ka-Jie, J Y M; Schuijers, F; Kooij, J J S

    2017-06-01

    Abnormal sensory sensitivity is a feature of autism-spectrum disorder (ASD), but is also reported in attention-deficit/hyperactivity disorder (ADHD). In many cases, ADHD and ASD are comorbid. This study investigated the prevalence of sensory hyper- and hyposensitivity among adults with ADHD, controlling for autistic symptoms. One hundred and sixteen adults diagnosed with ADHD completed the Adolescent/Adult Sensory Profile-NL (AASP-NL) and the Autism-spectrum Quotient (AQ) questionnaires. Prevalences of hyper- and hyposensitivity and autism-spectrum symptoms were compared to norm values. Multivariate binary logistic regressions were used to determine the association of autistic symptoms, age, gender, ADHD subtype, self-reported severity of ADHD symptoms, comorbid disorders, and use of medication on the sensory hypo- and hypersensitivity in adults with ADHD. Adults with ADHD had more autistic symptoms, and they had both more hyper- and hyposensitivity compared to norm groups. This was especially apparent in the Activity level and Auditory sensory modalities. Sensory hypo- and hypersensitivity were both related to an increased ADHD score, even showing a dose-response relationship, but not to any autistic symptom or comorbid disorder. As much as 43% of the females with ADHD reported sensory hypo- and/or hypersensitivity, compared to 22% of the men. Sensory hypo- and hypersensitivity may be viewed as key features of adult ADHD, especially in females, regardless of any autistic symptoms. Future research should be directed at the implications of this sensory dysregulation for the understanding of the pathophysiology of (female) ADHD, and on the usefulness of assessment of atypical sensory profiles in the diagnostic procedure of ADHD in adults. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  1. Nursing research. Components of a clinical research study.

    Science.gov (United States)

    Bargagliotti, L A

    1988-09-01

    Nursing research is the systematic collection and analysis of data about clinically important phenomena. While there are norms for conducting research and rules for using certain research procedures, the reader must always filter the research report against his or her nursing knowledge. The most common questions a reader should ask are "Does it make sense? Can I think of any other reasonable explanation for the findings? Do the findings fit what I have observed?" If the answers are reasonable, research findings from carefully conducted studies can provide a basis for making nursing decisions. One of the earliest accounts of nursing research, which indicates the power of making systematic observations, was Florence Nightingale's study. It compared deaths among soldiers in the Crimean War with deaths of soldiers in the barracks of London. Her research demonstrated that soldiers in the barracks had a much higher death rate than did the soldiers at war. On the basis of the study, sanitary conditions in the barracks were changed substantially.

  2. Accelerator research studies. Progress report

    International Nuclear Information System (INIS)

    1983-07-01

    The major goal of this project is to study the effects that lead to emittance growth and limitation of beam current and brightness in periodic focusing systems (including linear accelerators). This problem is of great importance for all accelerator applications requiring high intensity beams with small emittance such as heavy ion fusion, spallation neutron sources and high energy physics. In the latter case, future machines must not only provide higher energies (in the range of 10 to 100 TeV), but also higher luminosities than the existing facilities. This implies considerably higher phase-space density of the particle beam produced by the injector linac, i.e., the detrimental emittance growth and concurrent beam loss observed in existing linacs must be avoided

  3. Qualitative Case Study Research as Empirical Inquiry

    Science.gov (United States)

    Ellinger, Andrea D.; McWhorter, Rochell

    2016-01-01

    This article introduces the concept of qualitative case study research as empirical inquiry. It defines and distinguishes what a case study is, the purposes, intentions, and types of case studies. It then describes how to determine if a qualitative case study is the preferred approach for conducting research. It overviews the essential steps in…

  4. Carotid Artery Intima-Media Thickness Predicts Major Cardiovascular Events During 7-Year Follow-Up in 64-Year-Old Women Irrespective of Other Glucometabolic Factors.

    Science.gov (United States)

    Schmidt, Caroline; Bergström, Göran

    2017-07-01

    Cardiovascular (CV) disease (CVD) is a leading cause of morbidity and mortality worldwide. Most CV events are caused by atherosclerosis. Diabetes and impaired glucose tolerance are associated with greater carotid intima-media thickness (IMT) and increased risk for CVD. The present study examined if common carotid artery IMT (CCAIMT) is predictive of CVD irrespective of glucose tolerance category and glycated hemoglobin (HbA1c) in a sample of 639 women with different glucose tolerance categories. During 7-year follow-up, 30 events in the cardiac and 32 events in the cerebral territory were documented. Unadjusted Cox hazard models showed that CCAIMT, glucose tolerance category, and HbA1c were associated with increased risk. An adjusted and extended model, including CCAIMT, glucose tolerance category, and HbA1c, showed that CCAIMT was still associated with events with an almost unchanged hazard ratio. In conclusion, this study suggests that CCAIMT is predictive of major CV events during 7-year follow-up, irrespective of glucose tolerance category, HbA1c, and other established risk factors in a cohort of 64-year-old women.

  5. Schematic representation of case study research designs.

    Science.gov (United States)

    Rosenberg, John P; Yates, Patsy M

    2007-11-01

    The paper is a report of a study to demonstrate how the use of schematics can provide procedural clarity and promote rigour in the conduct of case study research. Case study research is a methodologically flexible approach to research design that focuses on a particular case - whether an individual, a collective or a phenomenon of interest. It is known as the 'study of the particular' for its thorough investigation of particular, real-life situations and is gaining increased attention in nursing and social research. However, the methodological flexibility it offers can leave the novice researcher uncertain of suitable procedural steps required to ensure methodological rigour. This article provides a real example of a case study research design that utilizes schematic representation drawn from a doctoral study of the integration of health promotion principles and practices into a palliative care organization. The issues discussed are: (1) the definition and application of case study research design; (2) the application of schematics in research; (3) the procedural steps and their contribution to the maintenance of rigour; and (4) the benefits and risks of schematics in case study research. The inclusion of visual representations of design with accompanying explanatory text is recommended in reporting case study research methods.

  6. A Rapid Subcortical Amygdala Route for Faces Irrespective of Spatial Frequency and Emotion.

    Science.gov (United States)

    McFadyen, Jessica; Mermillod, Martial; Mattingley, Jason B; Halász, Veronika; Garrido, Marta I

    2017-04-05

    There is significant controversy over the existence and function of a direct subcortical visual pathway to the amygdala. It is thought that this pathway rapidly transmits low spatial frequency information to the amygdala independently of the cortex, and yet the directionality of this function has never been determined. We used magnetoencephalography to measure neural activity while human participants discriminated the gender of neutral and fearful faces filtered for low or high spatial frequencies. We applied dynamic causal modeling to demonstrate that the most likely underlying neural network consisted of a pulvinar-amygdala connection that was uninfluenced by spatial frequency or emotion, and a cortical-amygdala connection that conveyed high spatial frequencies. Crucially, data-driven neural simulations revealed a clear temporal advantage of the subcortical connection over the cortical connection in influencing amygdala activity. Thus, our findings support the existence of a rapid subcortical pathway that is nonselective in terms of the spatial frequency or emotional content of faces. We propose that that the "coarseness" of the subcortical route may be better reframed as "generalized." SIGNIFICANCE STATEMENT The human amygdala coordinates how we respond to biologically relevant stimuli, such as threat or reward. It has been postulated that the amygdala first receives visual input via a rapid subcortical route that conveys "coarse" information, namely, low spatial frequencies. For the first time, the present paper provides direction-specific evidence from computational modeling that the subcortical route plays a generalized role in visual processing by rapidly transmitting raw, unfiltered information directly to the amygdala. This calls into question a widely held assumption across human and animal research that fear responses are produced faster by low spatial frequencies. Our proposed mechanism suggests organisms quickly generate fear responses to a wide range

  7. Research studies with the International Ultraviolet Explorer

    Science.gov (United States)

    1991-01-01

    The IUE research studies comprises 118 separate research programs involving observations, data analysis, and research conducted of the IUE satellite and the NASA Astrophysics Data Program. Herein are presented 92 programs. For each program there is a title, program ID, name of the investigator, statement of work, summary of results, and list of publications.

  8. Writing case studies in information systems research

    NARCIS (Netherlands)

    van der Blonk, H.C.

    Case study research can be reported in different ways. This paper explores the various ways in which researchers may choose to write down their case studies and then introduces a subsequent typology of writing case studies. The typology is based on a 2 x 2 matrix, resulting in four forms of writing

  9. LED lighting increases the ecological impact of light pollution irrespective of color temperature.

    Science.gov (United States)

    Pawson, S M; Bader, M K-F

    Recognition of the extent and magnitude of night-time light pollution impacts on natural ecosystems is increasing, with pervasive effects observed in both nocturnal and diurnal species. Municipal and industrial lighting is on the cusp of a step change where energy-efficient lighting technology is driving a shift from “yellow” high-pressure sodium vapor lamps (HPS) to new “white” light-emitting diodes (LEDs). We hypothesized that white LEDs would be more attractive and thus have greater ecological impacts than HPS due to the peak UV-green-blue visual sensitivity of nocturnal invertebrates. Our results support this hypothesis; on average LED light traps captured 48% more insects than were captured with light traps fitted with HPS lamps, and this effect was dependent on air temperature (significant light × air temperature interaction). We found no evidence that manipulating the color temperature of white LEDs would minimize the ecological impacts of the adoption of white LED lights. As such, large-scale adoption of energy-efficient white LED lighting for municipal and industrial use may exacerbate ecological impacts and potentially amplify phytosanitary pest infestations. Our findings highlight the urgent need for collaborative research between ecologists and electrical engineers to ensure that future developments in LED technology minimize their potential ecological effects.

  10. Unveiling Research Agendas: a study of the influences on research problem selection among academic researchers

    Energy Technology Data Exchange (ETDEWEB)

    Bianco, M.; Sutz, J.

    2016-07-01

    Research problem selection is central to the dynamics of scientific knowledge production. Research agendas result from the selection of research problems and the formulation of individual and/or collective academic strategies to address them. But, why researchers study what they study? This paper presents incipient research focused on the way different factors influence the construction of academic research agendas. It takes a researcher-oriented approach relying on opinions and perspectives of a wide range of researchers in all fields of knowledge. The empirical work is carried out in Uruguay, a country in the periphery of mainstream science, whose academic community struggles in search of a balance between the requirements of the world community of scholars and the demands from different national stakeholders. The methodology and research results from this study may be relevant to other countries, at different peripheries. Further, understanding the interplay of influences that shape research agendas is an important tool for policy analysis and planning everywhere. (Author)

  11. Investigating educational research. A study on dissertations

    Directory of Open Access Journals (Sweden)

    Paulo Marcelo Marini Teixeira

    2006-08-01

    Full Text Available This paper is a brief historical survey on the emergence of educational research in Brazil, namely the rise and development of Science Education research, with special focus on research developed in Education and Science Education graduate programs. It highlights the relevance of the so-called ‘state-of-the-art” studies as a category of investigation that is fundamental for analytical studies on production in a given field of research, and addresses basic procedures to be carried out in investigations of this nature. Finally, this paper presents some trends in Biology Education research in Brazil as shown in Brazilian dissertations and theses produced between 1972 and 2003.

  12. Equally increased hypercoagulability irrespective of using minimized or conventional ECC systems

    DEFF Research Database (Denmark)

    Steinbrüchel, Ann S; Johansson, Pär I; Rafiq, Sulman

    2012-01-01

    Minimized extracorporeal circulation systems in coronary artery bypass may have less impairing effect on hematological parameters and bleeding compared to conventional systems. The aim of this study was to investigate whether the use of mini systems does result in an increased postoperative...

  13. [Reduced risk of stroke recurrence due to hypotensive medication, irrespective of the initial blood pressure

    NARCIS (Netherlands)

    Lenders, J.W.M.; Thien, Th.

    2002-01-01

    The 'Perindopril protection against recurrent stroke study' (PROGRESS) demonstrated that for patients with a history of stroke or transient ischaemic attack during the previous 5 years, a blood-pressure-lowering regimen based on the combination of a diuretic and an angiotensin-converting enzyme

  14. Age and Menopausal Status Affect Osteoprotegerin and Osteocalcin Levels in Women Differently, Irrespective of Thyroid Function

    Directory of Open Access Journals (Sweden)

    Alexander D. Shinkov

    2014-01-01

    Full Text Available Osteoprotegerin (OPG and osteocalcin (OC are essential bone proteins. Recent studies have demonstrated that they are not secreted solely by bone cells; they play roles in the vascular function and energy metabolism, and they are influenced by multiple factors. The aim of the current study was to investigate the influence of menopause and age on OPG and OC in women with different thyroid-stimulating hormone (TSH levels. Material and Methods We studied 49 women with elevated TSH, 26 with suppressed TSH, and 67 age-matched euthyroid controls. Of them 64 were menstruating and 78 postmenopausal. Body weight, height, waist circumference (WC, body mass index (BMI, serum TSH, free thyroxin (FT4, OPG, and OC were measured. Results Generally, both OPG and OC were higher in the postmenopausal women than in the menstruating subjects (OPG 3.85 ± 1.49 pmol/L vs. 5.84 ± 2.42 pmol/L, P < 0.001; OC 8.84 ± 3.70 ng/dL vs. 12.87 ± 6.45 ng/dL, P < 0.001, and within the two thyroid dysfunction subgroups and the controls (all P < 0.05. OPG correlated with age (postmenopausal rho = 0.57, P < 0.001; premenopausal rho = 0.31, P = 0.015. Among the premenopausal subjects, OPG was higher in those with low TSH than in the controls ( P = 0.048. OC correlated negatively with BMI and WC in the postmenopausal group (Spearman rho = –-0.25, P = 0.03 and rho = –-0.42, P < 0.001 respectively. OC was higher in the postmenopausal subjects with low TSH than in those with elevated TSH ( P = 0.024, and correlated positively with FT4 (rho = 0.40, P = 0.002 and negatively with TSH (rho = -0.29, P = 0.013. CONCLUSIONS In women, OPG and OC depended differently on age and menopause and, to a lesser extent, on the thyroid function and body composition.

  15. International Research Study of Public Procurement

    NARCIS (Netherlands)

    Telgen, Jan; Harland, C.; Callender, G.; Harland, C.; Nassimbeni, G.; Schneller, E.

    2012-01-01

    In this chapter we examine the specific issue of public procurement, its importance to local, regional, national, and international economies as evidenced in a unique international comparative research study – the International Research Study of Public Procurement (IRSPP). First the public

  16. Conceptions of learning research: variations amongst French and Swedish nurses. A phenomenographic study.

    Science.gov (United States)

    Dupin, Cécile Marie; Larsson, Maria; Dariel, Odessa; Debout, Christophe; Rothan-Tondeur, Monique

    2015-01-01

    The development of nursing research capacity and interactions with cultural and structural issues is at various stages throughout Europe. This process appears to be remarkably similar irrespective of the country. Sweden has developed this capacity since the 1990s, whereas France is experiencing a transition. Nevertheless, knowledge about how nurses conceive their learning about nursing research and transitioning toward being researchers is scarce. The aim of this study was to explore French and Swedish RNs' conceptions of research education and educational passage toward research and to describe how learning research contributes to the understanding of their norms and practices. A phenomenographic approach was used to understand and describe the qualitatively different ways in which French and Swedish RNs conceive research and its apprenticeship. A purposive maximum variation sampling of five French and five Swedish Nurse Researchers with PhDs. Individual in-depth interviews conducted in France and Sweden between November 2012 and March 2013 were analysed using phenomenography. The analysis revealed one main category, "Organisational factors to sustain individual apprenticeship". Three descriptive categories have emerged from the data and its variations amongst French and Swedish nurses: (1) entrance into research--modes of commitment; (2) nurses' engagement--the need for dedicated support; and (3) research as the means to resolve nursing situations. This study demonstrates how registered nurses have integrated nursing and researcher roles following different efficient paths. Education in nursing research is part of the strategy needed for the development of nursing research and is supported by the integration of research and practice. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Superinfection occurs in Anaplasma phagocytophilum infected sheep irrespective of infection phase and protection status

    Directory of Open Access Journals (Sweden)

    Bergström Karin

    2009-10-01

    Full Text Available Abstract Background Anaplasma phagocytophilum infection in domestic ruminants is widespread in the coastal areas of southern Norway. The bacteria may persist in mammalian hosts. Several genetic variants of A. phagocytophilum exist. In the present study, we investigate whether superinfection occurs in the acute and persistent phase of the infection. Methods Five-month-old lambs of the Norwegian Dala breed were experimentally infected with two 16S rRNA gene variants of A. phagocytophilum, i.e. A. phagocytophilum variant 1 (GenBank accession number M73220 and variant 2 (GenBank acc. no. AF336220. Eighteen lambs were used, two lambs in each group. Eight groups were experimentally inoculated with either variant 1 or 2 on day 0. Six of these groups were then challenged with the other variant on either days 7, 42 or 84, respectively. One group was left uninfected. The occurrence of A. phagocytophilum in blood samples was determined using semi-nested PCR analysis and gene sequencing. Specific antibodies were measured by an indirect immunofluorescence antibody assay (IFA. Results A. phagocytophilum variant 1 and 2 differed significantly with regards to clinical reaction and cross-immunity in infected lambs. Both variants were found in the blood after challenge. However, variant 1 was detected most frequently. Conclusion The present experiment indicates that superinfection of different genotypes occurs during the acute as well as the persistent phase of an A. phagocytophilum infection, even in lambs protected against the challenged infection.

  18. Summer Undergraduate Research Program: Environmental studies

    Energy Technology Data Exchange (ETDEWEB)

    McMillan, J. [ed.

    1994-12-31

    The purpose of the summer undergraduate internship program for research in environmental studies is to provide an opportunity for well-qualified students to undertake an original research project as an apprentice to an active research scientist in basic environmental research. The students are offered research topics at the Medical University in the scientific areas of pharmacology and toxicology, epidemiology and risk assessment, environmental microbiology, and marine sciences. Students are also afforded the opportunity to work with faculty at the University of Charleston, SC, on projects with an environmental theme. Ten well-qualified students from colleges and universities throughout the eastern United States were accepted into the program.

  19. Research Methods in European Union Studies

    DEFF Research Database (Denmark)

    Lynggaard, Kennet; Manners, Ian; Löfgren, Karl

    Research on the European Union over the past few years has been strongly implicated in the crises that currently grip Europe with a failure to ask the pertinent questions as well as a perceived weakness in the methods and evidence used by researchers providing the basis for these allegations....... This volume moves the study of EU research strategies beyond the dichotomies of the past towards a new agenda for research on Europe through a rich diversity of problem-solving based research. This new agenda acknowledges the weaknesses of the past and moves beyond them towards greater openness and awareness...

  20. Compression stockings significantly improve hemodynamic performance in post-thrombotic syndrome irrespective of class or length.

    Science.gov (United States)

    Lattimer, Christopher R; Azzam, Mustapha; Kalodiki, Evi; Makris, Gregory C; Geroulakos, George

    2013-07-01

    Graduated elastic compression (GEC) stockings have been demonstrated to reduce the morbidity associated with post-thrombotic syndrome. The ideal length or compression strength required to achieve this is speculative and related to physician preference and patient compliance. The aim of this study was to evaluate the hemodynamic performance of four different stockings and determine the patient's preference. Thirty-four consecutive patients (40 legs, 34 male) with post-thrombotic syndrome were tested with four different stockings (Mediven plus open toe, Bayreuth, Germany) of their size in random order: class 1 (18-21 mm Hg) and class II (23-32 mm Hg), below-knee (BK) and above-knee thigh-length (AK). The median age, Venous Clinical Severity Score, Venous Segmental Disease Score, and Villalta scale were 62 years (range, 31-81 years), 8 (range, 1-21), 5 (range, 2-10), and 10 (range, 2-22), respectively. The C of C0-6EsAs,d,pPr,o was C0 = 2, C2 = 1, C3 = 3, C4a = 12, C4b = 7, C5 = 12, C6 = 3. Obstruction and reflux was observed on duplex in 47.5% legs, with deep venous reflux alone in 45%. Air plethysmography was used to measure the venous filling index (VFI), venous volume, and time to fill 90% of the venous volume. Direct pressure measurements were obtained while lying and standing using the PicoPress device (Microlab Elettronica, Nicolò, Italy). The pressure sensor was placed underneath the test stocking 5 cm above and 2 cm posterior to the medial malleolus. At the end of the study session, patients stated their preferred stocking based on comfort. The VFI, venous volume, and time to fill 90% of the venous volume improved significantly with all types of stocking versus no compression. In class I, the VFI (mL/s) improved from a median of 4.9 (range, 1.7-16.3) without compression to 3.7 (range, 0-14) BK (24.5%) and 3.6 (range, 0.6-14.5) AK (26.5%). With class II, the corresponding improvement was to 4.0 (range, 0.3-16.2) BK (18.8%) and 3.7 (range, 0.5-14.2) AK (24

  1. Research Approaches in the Study of Religion

    Directory of Open Access Journals (Sweden)

    Szocik Konrad

    2015-02-01

    Full Text Available Despite development of secular ideas and concepts in the Western world, we can observe increasing interest in the study of religion. However, this popularity of the study of religion and different research approaches has caused that in some sense scholars that were studying religion came to a dead point. Here I show that the most optimal research approach in the study of religion is pluralistic, integral paradigm which connects old traditional methods with naturalistic, cognitive and sometimes experimental approach.

  2. Case Study Research: Foundations and Methodological Orientations

    Directory of Open Access Journals (Sweden)

    Helena Harrison

    2017-01-01

    Full Text Available Over the last forty years, case study research has undergone substantial methodological development. This evolution has resulted in a pragmatic, flexible research approach, capable of providing comprehensive in-depth understanding of a diverse range of issues across a number of disciplines. Change and progress have stemmed from parallel influences of historical transformations in approaches to research and individual researcher's preferences, perspectives, and interpretations of this design. Researchers who have contributed to the development of case study research come from diverse disciplines with different philosophical perspectives, resulting in a variety of definitions and approaches. For the researcher new to using case study, such variety can create a confusing platform for its application. In this article, we explore the evolution of case study research, discuss methodological variations, and summarize key elements with the aim of providing guidance on the available options for researchers wanting to use case study in their work. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1701195

  3. Clinical Research Informatics: Supporting the Research Study Lifecycle.

    Science.gov (United States)

    Johnson, S B

    2017-08-01

    Objectives: The primary goal of this review is to summarize significant developments in the field of Clinical Research Informatics (CRI) over the years 2015-2016. The secondary goal is to contribute to a deeper understanding of CRI as a field, through the development of a strategy for searching and classifying CRI publications. Methods: A search strategy was developed to query the PubMed database, using medical subject headings to both select and exclude articles, and filtering publications by date and other characteristics. A manual review classified publications using stages in the "research study lifecycle", with key stages that include study definition, participant enrollment, data management, data analysis, and results dissemination. Results: The search strategy generated 510 publications. The manual classification identified 125 publications as relevant to CRI, which were classified into seven different stages of the research lifecycle, and one additional class that pertained to multiple stages, referring to general infrastructure or standards. Important cross-cutting themes included new applications of electronic media (Internet, social media, mobile devices), standardization of data and procedures, and increased automation through the use of data mining and big data methods. Conclusions: The review revealed increased interest and support for CRI in large-scale projects across institutions, regionally, nationally, and internationally. A search strategy based on medical subject headings can find many relevant papers, but a large number of non-relevant papers need to be detected using text words which pertain to closely related fields such as computational statistics and clinical informatics. The research lifecycle was useful as a classification scheme by highlighting the relevance to the users of clinical research informatics solutions. Georg Thieme Verlag KG Stuttgart.

  4. Research Strategies in European Union Studies

    DEFF Research Database (Denmark)

    Manners, Ian James; Lynggaard, Kennet; Löfgren, Karl

    2015-01-01

    The contributing chapters of this book all illustrate the richness and diversity of problem-driven research in EU studies. This concluding chapter draws together the insights of this rich diversity in order to move the study of research strategies beyond the dichotomies of the past towards a new...... agenda for research on Europe. The crisis gripping the EU in the 21st century is not just an economic crisis, it is a crisis of belief in the EU. Research on the EU is deeply implicated in this crisis, not least because of the questions it does not ask, but also because of the pereceived weakness...... of demonstrating the methods and evidence used. A new agenda for research on Europe needs to acknowledge these weaknesses of the past and move beyond dichotomies towards greater awareness and openesss of the importance of research strategies, designs and methods....

  5. Can legal research benefit from evaluation studies?

    Directory of Open Access Journals (Sweden)

    Frans L. Leeuw

    2011-01-01

    Full Text Available The article describes what evaluation studies have to offer to legal research. Several cases and types of evaluations are presented, in relation to legal or semi-legal questions. Also, a short overview of the contemporary history of evaluation studies is presented. Finally, it will address the question of how to ensure that in legal research and in legal training attention is paid to theories, designs and methods of evaluation studies.

  6. Solar energy storage researchers information user study

    Energy Technology Data Exchange (ETDEWEB)

    Belew, W.W.; Wood, B.L.; Marle, T.L.; Reinhardt, C.L.

    1981-03-01

    The results of a series of telephone interviews with groups of users of information on solar energy storage are described. In the current study only high-priority groups were examined. Results from 2 groups of researchers are analyzed: DOE-Funded Researchers and Non-DOE-Funded Researchers. The data will be used as input to the determination of information products and services the Solar Energy Research Institute, the Solar Energy Information Data Bank Network, and the entire information outreach community should be preparing and disseminating.

  7. Case Study Methodology and Homelessness Research

    Directory of Open Access Journals (Sweden)

    Jill Pable

    2013-10-01

    Full Text Available This paper describes the potential suitability of case study methodology for inquiry with the homeless population. It references a research study that uses case study research method to build theory. This study's topic is the lived experience of destitute individuals who reside in homeless shelters, and explores the homeless shelter built environment's potential influence on resident satisfaction and recovery. Case study methodology may be appropriate because it explores real-life contextual issues that characterize homelessness and can also accommodate the wide range of homeless person demographics that make this group difficult to study in a generalized fashion. Further, case study method accommodates the need within research in this area to understand individualized treatments as a potential solution for homelessness.

  8. Political Socialization Research and Canadian Studies

    Science.gov (United States)

    Tomkins, George S.

    1977-01-01

    Presents a review of the burgeoning field of Canadian political socialization research as it applies to children and youth, and considers some implications of recent findings for the Canadian studies curriculum. (Editor)

  9. Innovative Interpretive Qualitative Case Study Research Method ...

    African Journals Online (AJOL)

    lc2o

    The combined use of case study and systems theory is rarely discussed in the ... Scott, 2002), the main benefit of doing qualitative research is the patience ..... Teaching ICT to teacher candidates ... English Language Teachers. London: Arnold.

  10. Public education and enforcement research study (PEERS).

    Science.gov (United States)

    2013-08-01

    In 2001, the Federal Railroad Administration (FRA) and the Illinois Commerce Commission (ICC) established the Public Education and Enforcement Research Study (PEERS) to test the effectiveness of various education and enforcement (E&E) techniques to i...

  11. Towards More Case Study Research in Entrepreneurship

    Directory of Open Access Journals (Sweden)

    Tom Duxbury

    2012-03-01

    Full Text Available Entrepreneurship as an emerging discipline has made good strides, but according to some, has fallen short of bringing its theory and literature up to the standards of others in the management sciences. Rich with the descriptive detail needed for insightful theory building in entrepreneurship, scholars have called for more case study research, particularly those incorporating non-retrospective and longitudinal observations. At the same time however, it has become rare to find such research published in A-level journals dedicated to entrepreneurship. A survey presented here of major entrepreneurship journals over the past six years revealed a publication rate of only 3% using the case study method. This presents a major impediment for developing fresh research in this field based upon the study of real cases. The author explores how the case study method has been applied to entrepreneurship research and provides recommendations for improved publication rates.

  12. Oral supplementation of Bifidobacterium longum strain BR-108 alters cecal microbiota by stimulating gut immune system in mice irrespectively of viability.

    Science.gov (United States)

    Makioka, Yuko; Tsukahara, Takamitsu; Ijichi, Tetsuo; Inoue, Ryo

    2018-03-20

    Effect on cecal microbiota and gene expression of various cytokines in ileal Peyer's patches and cecal tissues were compared between viable and heat-killed Bifidobacterium longum strain BR-108 (BR-108) using a mouse model. Irrespectively of viability, oral supplementation of BR-108 altered the cecal microbiota and stimulated gene expression of cytokines such as IL-6 and IL-10 in ileal Peyer's patches and cecal tissue of mice. In addition, BR-108 supplementation significantly affected the relative abundance of bacterial genera and family, Oscillospira, Bacteroides and S24-7. The abundance of these bacterial genera and family strongly correlated with gene expression induced by BR-108. This study demonstrated that the effect of heat-killed BR-108 on the mouse cecal microbiota is similar to that of viable BR-108, most likely due to stimulation of the gut immune system by both heat-killed and viable BR-108 is also similar.

  13. Rigour in qualitative case-study research.

    Science.gov (United States)

    Houghton, Catherine; Casey, Dympna; Shaw, David; Murphy, Kathy

    2013-03-01

    To provide examples of a qualitative multiple case study to illustrate the specific strategies that can be used to ensure the credibility, dependability, confirmability and transferability of a study. There is increasing recognition of the valuable contribution qualitative research can make to nursing knowledge. However, it is important that the research is conducted in a rigorous manner and that this is demonstrated in the final research report. A multiple case study that explored the role of the clinical skills laboratory in preparing students for the real world of practice. Multiple sources of evidence were collected: semi-structured interviews (n=58), non-participant observations at five sites and documentary sources. Strategies to ensure the rigour of this research were prolonged engagement and persistent observation, triangulation, peer debriefing, member checking, audit trail, reflexivity, and thick descriptions. Practical examples of how these strategies can be implemented are provided to guide researchers interested in conducting rigorous case study research. While the flexible nature of qualitative research should be embraced, strategies to ensure rigour must be in place.

  14. Ocean energy researchers information user study

    Energy Technology Data Exchange (ETDEWEB)

    Belew, W.W.; Wood, B.L.; Marle, T.L.; Reinhardt, C.L.

    1981-03-01

    This report describes the results of a series of telephone interviews with groups of users of information on ocean energy systems. These results, part of a larger study on many different solar technologies, identify types of information each group needed and the best ways to get information to each group. The report is 1 of 10 discussing study results. The overall study provides baseline data about information needs in the solar community. Only high-priority groups were examined. Results from 2 groups of researchers are analyzed in this report: DOE-Funded Researchers and Non-DOE-Funded Researchers. The data will be used as input to the determination of information products and services the Solar Energy Research Institute, the Solar Energy Information Data Bank Network, and the entire information outreach community should be preparing and disseminating.

  15. Ipragliflozin Improves Hepatic Steatosis in Obese Mice and Liver Dysfunction in Type 2 Diabetic Patients Irrespective of Body Weight Reduction.

    Directory of Open Access Journals (Sweden)

    Chikara Komiya

    Full Text Available Type 2 diabetes mellitus (T2DM is associated with a high incidence of non-alcoholic fatty liver disease (NAFLD related to obesity and insulin resistance. Currently, medical interventions for NAFLD have focused on diet control and exercise to reduce body weight, and there is a requirement for effective pharmacological therapies. Sodium-glucose cotransporter 2 (SGLT2 inhibitors are oral antidiabetic drugs that promote the urinary excretion of glucose by blocking its reabsorption in renal proximal tubules. SGLT2 inhibitors lower blood glucose independent of insulin action and are expected to reduce body weight because of urinary calorie loss. Here we show that an SGLT2 inhibitor ipragliflozin improves hepatic steatosis in high-fat diet-induced and leptin-deficient (ob/ob obese mice irrespective of body weight reduction. In the obese mice, ipragliflozin-induced hyperphagia occurred to increase energy intake, attenuating body weight reduction with increased epididymal fat mass. There is an inverse correlation between weights of liver and epididymal fat in ipragliflozin-treated obese mice, suggesting that ipragliflozin treatment promotes normotopic fat accumulation in the epididymal fat and prevents ectopic fat accumulation in the liver. Despite increased adiposity, ipragliflozin ameliorates obesity-associated inflammation and insulin resistance in epididymal fat. Clinically, ipragliflozin improves liver dysfunction in patients with T2DM irrespective of body weight reduction. These findings provide new insight into the effects of SGLT2 inhibitors on energy homeostasis and fat accumulation and indicate their potential therapeutic efficacy in T2DM-associated hepatic steatosis.

  16. Poultry studies and anthropological research strategies

    International Nuclear Information System (INIS)

    Whyte, M.

    2002-01-01

    Poultry are not simply birds; they are also a human creation, a social and cultural practice. The human element is the justification for an anthropology of poultry. Such an anthropology combines the objective research strategies familiar to the natural sciences with what is often called 'subjective' or qualitative research. In the study of poultry management, it is important that both research strategies focus on differences and variation. The subjective approach is particularly useful in identifying and understanding how the motivations and strategies of local actors are dependent on the social positions, which they occupy in their specific societies. (author)

  17. Indtroduction To Research Methodologies In Language Studies

    Directory of Open Access Journals (Sweden)

    Muhartoyo Muhartoyo

    2007-05-01

    Full Text Available Penelitian bahasa merupakan bidang yang menarik bagi mahasiswa dan pengajar di Fakultas Sastra. Artikel ini mencoba menggambarkan berbagai metodologi riset dalam bidang bahasa dengan cara yang sederhana. Metodologi riset ini mencakup experimental research, quasi experimental research, etnografi, dan studi kasus. Artikel ini juga membahas konsep metode riset kuantitatif dan kualitatif. Masalah validitas dan keabsahan sebuah laporan riset dibahas secara singkat.

  18. Five Misunderstandings About Case-Study Research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    2006-01-01

    This article examines five common misunderstandings about case-study research: (a) theoretical knowledge is more valuable than practical knowledge; (b) one cannot generalize from a single case, therefore, the single-case study cannot contribute to scientific development; (c) the case study is most...... useful for generating hypotheses, whereas other methods are more suitable for hypotheses testing and theory building; (d) the case study contains a bias toward verification; and (e) it is often difficult to summarize specific case studies. This article explains and corrects these misunderstandings one...

  19. Mapping Translation Technology Research in Translation Studies

    DEFF Research Database (Denmark)

    Schjoldager, Anne; Christensen, Tina Paulsen; Flanagan, Marian

    2017-01-01

    /Schjoldager 2010, 2011; Christensen 2011). Unfortunately, the increasing professional use of translation technology has not been mirrored within translation studies (TS) by a similar increase in research projects on translation technology (Munday 2009: 15; O’Hagan 2013; Doherty 2016: 952). The current thematic...... section aims to improve this situation by presenting new and innovative research papers that reflect on recent technological advances and their impact on the translation profession and translators from a diversity of perspectives and using a variety of methods. In Section 2, we present translation...... technology research as a subdiscipline of TS, and we define and discuss some basic concepts and models of the field that we use in the rest of the paper. Based on a small-scale study of papers published in TS journals between 2006 and 2016, Section 3 attempts to map relevant developments of translation...

  20. American Indian Studies. Library Research Guide.

    Science.gov (United States)

    White, Phillip M.

    This guide to sources for students at San Diego State University doing library research in topics related to American Indian Studies begins by noting that information on North American Indians can be found in a variety of subject disciplines including history, anthropology, education, sociology, health care, law, business, and politics. The…

  1. The Evolution of Family Studies Research.

    Science.gov (United States)

    Emery, Beth C.; Lloyd, Sally A.

    2001-01-01

    This review of methodological, theoretical, and topical trends in family studies research covers changes in definitions of family and in marriage, parent-child relationships, and family social ecology. Issues discussed include marital satisfaction, violence, social construction of gender, family-work relationship, parenting roles, socialization,…

  2. Jupiter Environmental Research & Field Studies Academy.

    Science.gov (United States)

    Huttemeyer, Bob

    1996-01-01

    Describes the development and workings of the Jupiter Environmental Research and Field Studies Academy that focuses on enabling both teachers and students to participate in real-life learning experiences. Discusses qualifications for admittance, curriculum, location, ongoing projects, students, academics, preparation for life, problem solving, and…

  3. Local Skills Case Study. Research Report

    Science.gov (United States)

    Green, Anne; Hogarth, Terence; Thom, Graham; MacLeod, Katie; Warhurst, Chris; Willis, Robert; Mackay, Susan

    2017-01-01

    This study, jointly conducted by the University of Warwick Institute for Employment Research (IER) and SQW Ltd., discusses the UK Government's intention to accelerate the process of ceding more responsibility for delivering a range of services to the local level. The logic is that local actors are better placed to identify local priorities. This…

  4. Study on the decommissioning of research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Doo Hwan; Jun, Kwan Sik; Choi, Yoon Dong; Lee, Tae Yung; Kwon, Sang Woon; Lee, Jong Il [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1995-01-01

    Currently, KAERI operates TRIGA Mark-II and TRIGA Mark-III research reactors as a general purpose research and training facility. As these are, however, situated at Seoul office site of KAERI which is scheduled to be transferred to KEPCO as well as 30 MW HANARO research reactor which is expected to reach the first criticality in 1995 is under construction at head site of KAERI, decommissioning of TRIGA reactors has become an important topic. The objective of this study is to prepare and present TRIGA facility decontamination and decommissioning plan. Estimation of the radioactive inventory in TRIGA research reactor was carried out by the use of computational method. In addition, summarized in particular were the methodologies associated with decontamination, segmenting processes for activated metallic components, disposition of wastes. Particular consideration in this study was focused available technology applicable to decommissioning of TRIGA research reactor. State-of-the-art summaries of the available technology for decommissioning presented here will serve a useful document for preparations for decommissioning in the future. 6 figs, 41 tabs, 30 refs. (Author).

  5. Integrated Food studies education and research:

    DEFF Research Database (Denmark)

    Hansen, Mette Weinreich; Hansen, Stine Rosenlund

    2018-01-01

    The research group Foodscapes Innovation and Networks has addressed integrated food studies issues in re-search and education since 2010. Based on experiences in the group, this paper aims at discussing the chal-lenges, learning outcomes and potentials for pushing an integrated thinking into rese......The research group Foodscapes Innovation and Networks has addressed integrated food studies issues in re-search and education since 2010. Based on experiences in the group, this paper aims at discussing the chal-lenges, learning outcomes and potentials for pushing an integrated thinking...... into research and education. It also addresses the challenges in integration when the methodological approaches and theoretical frameworks chosen are ontologically and epistemologically different. A discussion of the limitations of integration is thus also part of the paper. The conceptual framework...... of ontonorms (Mol, 2013) is suggested as a common point of departure for a further development of integration. This is suggested relevant due to the fact that it forces different traditions to reflect their own value-related basis and discuss implications of this approach in a broader sense. The common values...

  6. A study for the KAERI research tunnel

    Energy Technology Data Exchange (ETDEWEB)

    Kim, J.; Hwang, Y. S.; Park, H. S.; Park, S. K.; Park, B. Y.; Bang, K. S.; Kuh, J. H.; Kang, K. H

    1997-12-01

    Major goal of the R and D on the KAERI Research Tunnel in 1997 are 1) concept development of the KAERI research tunnel and its major units 2) computer simulation of facilities 3) study on thermo-hydro mechanical coupling in the vicinity of a waste repository 4) effect of excavated distrubed zone. In addition supplementary site investigation to understand the distribution of stresses in the site was done along with long term monitoring of the water table. (author). 44 refs., 16 tabs., 36 figs

  7. RNA localization in Xenopus oocytes uses a core group of trans-acting factors irrespective of destination.

    Science.gov (United States)

    Snedden, Donald D; Bertke, Michelle M; Vernon, Dominic; Huber, Paul W

    2013-07-01

    The 3' untranslated region of mRNA encoding PHAX, a phosphoprotein required for nuclear export of U-type snRNAs, contains cis-acting sequence motifs E2 and VM1 that are required for localization of RNAs to the vegetal hemisphere of Xenopus oocytes. However, we have found that PHAX mRNA is transported to the opposite, animal, hemisphere. A set of proteins that cross-link to the localization elements of vegetally localized RNAs are also cross-linked to PHAX and An1 mRNAs, demonstrating that the composition of RNP complexes that form on these localization elements is highly conserved irrespective of the final destination of the RNA. The ability of RNAs to bind this core group of proteins is correlated with localization activity. Staufen1, which binds to Vg1 and VegT mRNAs, is not associated with RNAs localized to the animal hemisphere and may determine, at least in part, the direction of RNA movement in Xenopus oocytes.

  8. PKCepsilon overexpression, irrespective of genetic background, sensitizes skin to UVR-induced development of squamous-cell carcinomas.

    Science.gov (United States)

    Sand, Jordan M; Aziz, Moammir H; Dreckschmidt, Nancy E; Havighurst, Thomas C; Kim, KyungMann; Oberley, Terry D; Verma, Ajit K

    2010-01-01

    Chronic exposure to UVR is the major etiologic factor in the development of human skin cancers including squamous-cell carcinoma (SCC). We have previously shown that protein Kinase C epsilon (PKCepsilon) transgenic mice on FVB/N background, which overexpress PKCepsilon protein approximately eightfold over endogenous levels in epidermis, exhibit about threefold more sensitivity than wild-type littermates to UVR-induced development of SCC. To determine whether it is PKCepsilon and not the mouse genetic background that determines susceptibility to UVR carcinogenesis, we cross-bred PKCepsilon FVB/N transgenic mice with SKH-1 hairless mice to generate PKCepsilon-overexpressing SKH-1 hairless mice. To evaluate the susceptibility of PKCepsilon SKH-1 hairless transgenic mice to UVR carcinogenesis, the mice were exposed to UVR (1-2 KJ m(-2)) three times weekly from a bank of six kodacel-filtered FS40 sunlamps. As compared with the wild-type hairless mice, PKCepsilon overexpression in SKH-1 hairless mice decreased the latency (12 weeks), whereas it increased the incidence (twofold) and multiplicity (fourfold) of SCC. The SKH hairless transgenic mice were observed to be as sensitive as FVB/N transgenic mice to UVR-induced development of SCC and expression of proliferative markers (proliferating cell nuclear antigen, signal transducers and activators of transcription 3, and extracellular signal-regulated kinase 1/2). The results indicate that PKCepsilon level dictates susceptibility, irrespective of genetic background, to UVR carcinogenesis.

  9. Decentralized energy studies: compendium of international studies and research

    Energy Technology Data Exchange (ETDEWEB)

    Wallace, C.

    1980-03-01

    The purpose of the compendium is to provide information about research activities in decentralized energy systems to researchers, government officials, and interested citizens. The compendium lists and briefly describes a number of studies in other industrialized nations that involve decentralized energy systems. A contact person is given for each of the activities listed so that interested readers can obtain more information.

  10. Studying and researching with social media

    CERN Document Server

    Poore, Megan

    2014-01-01

    Wondering what your lecturers are looking for in a blog post? Asking yourself how that's different from writing an essay (or a wiki page)? Unsure if Twitter really can be used to build your online profile as a researcher? If you want -- or need -- to integrate social media tools into your studies and research, this practical book is your one-stop shop. Megan Poore shares the secrets of how to harness the power of social media tools to improve your academic productivity. Inside, you'll find out how to: ...write a good blog post ...contribute to a wiki ...maximise your grades when creating an audio-visual presentation ...find and share the latest research via Twitter ...keep safe online. Featuring handy illustrations and exercises, as well as guidance on broader issues such as copyright, avoiding plagiarism, and cyberbullying, you'll find out all you need to successfully use social media to support your study and research. Megan Poore is Assistant Professor in Teacher Education at the University of Canberra.

  11. Five misunderstandings about Case-study Research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    This article examines five common misunderstandings about case-study research: (1) Theoretical knowledge is more valuable than practical knowledge; (2) One cannot generalize from a single case, therefore the single case study cannot contribute to scientific development; (3) The case study is most...... useful for generating hypotheses, while other methods aremore suitable for hypotheses testing and theory building; (4) The case study contains a bias toward verification; and (5) It is often difficult to summarize specific case studies. The article explains and corrects these misunderstandings one by one...... and concludes with the Kuhnian insight that a scientific discipline without a large number of thoroughly executed case studies is a discipline without systematic production of exemplars, and that a discipline without  exemplars is an ineffective one. Social science may be strengthened by the execution of more...

  12. Five misunderstandings about case study research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    2004-01-01

    This article examines five common misunderstandings about case-study research: (1) Theoretical knowledge is more valuable than practical knowledge; (2) One cannot generalize from a single case, therefore the single case study cannot contribute to scientific development; (3) The case study is most...... useful for generating hypotheses, while other methods aremore suitable for hypotheses testing and theory building; (4) The case study contains a bias toward verification; and (5) It is often difficult to summarize specific case studies. The article explains and corrects these misunderstandings one by one...... and concludes with the Kuhnian insight that a scientific discipline without a large number of thoroughly executed case studies is a discipline without systematic production of exemplars, and that a discipline without exemplars is an ineffective one. Social science may be strengthened by the execution of more...

  13. Prayer Healing: A Case Study Research Protocol.

    Science.gov (United States)

    Kruijthoff, Dirk J; van der Kooi, Cornelis; Glas, Gerrit; Abma, Tineke A

    2017-01-01

    Context • Prayer healing is a common practice in many religious communities around the world. Even in the highly secularized Dutch society, cases of prayer healing are occasionally reported in the media, often generating public attention. There is an ongoing debate regarding whether such miraculous cures do actually occur and how to interpret them. Objective • The aim of the article was to present a research protocol for the investigation of reported cases of remarkable and/or unexplained healing after prayer. Design • The research team developed a method to perform a retrospective, case-based study of prayer healing. Reported prayer healings can be investigated systematically in accordance with a step-by-step methodology. The focus is on understanding the healing by studying it from multiple perspectives, using both medical judgment and patients' narratives collected by qualitative methods Setting • The study occurred at Vrije Universiteit (VU) and VU Medical Center (Amsterdam, Netherlands) as well as the general medical practice of the first author. Participants • Potential participants could be any individuals in the Netherlands or neighboring countries who claim to have been healed through prayer. The reports of healing came from multiple sources, including the research team's medical practices and their direct vicinities, newspaper articles, prayer healers, and medical colleagues. Outcome Measures • Medical data were obtained before and after prayer. Subsequently, a member of a research team and of a medical assessment committee made a standardized judgment that evaluated whether a cure was clinically remarkable or scientifically unexplained. The participants' experiences and insider perspectives were studied, using in-depth interviews in accordance with a qualitative research methodology, to gain insight into the perceptions and explanations of the cures that were offered by participants and by the members of the medical assessment committee. The

  14. Meteorological research studies at Jervis Bay, Australia

    International Nuclear Information System (INIS)

    Clark, G.H.; Bendun, E.O.K.

    1974-07-01

    A climatological study of the winds and temperature from the Jervis Bay region which commenced in October 1970 has shown the presence of a coastal sea breeze and secondary bay breeze circulation system. In an attempt to define the influence of the Murray's Beach site on the local atmospheric dispersion, special smoke plume photography studies were conducted in the lower atmosphere. In June 1972 a meteorological acoustic sounding research programme was initiated at the Jervis Bay settlement. The aims of the research are to calibrate the sounder in terms of surface wind, turbulence and temperature measurements pertinent to a description of the lower atmospheric dispersion potential. Preliminary results on six months' data have shown encouraging correlations between the acoustic sounder patterns and particularly the wind direction turbulence traces. (author)

  15. Accelerator research studies: Progress report, Task B

    International Nuclear Information System (INIS)

    1985-06-01

    The main objectives in Task B of the research program are summarized as follows: (1) studies of the collective acceleration of positive ions from a localized plasma source by an intense relativistic electron beam (IREB), (2) studies of ways in which external control may be achieved over the electron beam front in order to achieve higher ion energies - the Beam Front Accelerator (BFA) concept, and (3) study of electron and ion beam generation in a new kind of compact pulsed accelerator in which energy is stored inductively and switched using a plasma focus opening switch. During the past year, substantial progress was made in each of these areas. Our exploratory research on the collective acceleration of laser-produced ions has confirmed the acceleration of C, Al, and Fe ions to peak energies in excess of 10 MeV/amu. In addition, studies of the relation between collective ion acceleration and electron beam propagation in vacuum have shed new light on the experimental processes that lead to energy transfer from electrons to ions. Meanwhile, extensive progress has been made in our attempts to use analytical theory and numerical simulation to model ion acceleration in these systems. Our resultant improved understanding of the processes that limit the peak ion energy has had a profound impact on our plans for further research in this area. Studies of the Compact Pulsed Accelerator have included both ion and electron beam extraction from the device. Its potential to reduce the volume of pulse power sources by an order of magnitude has already been demonstrated, and plans are currently underway to scale the experiment up to voltages in the 1 MV range

  16. Tire Crumb Research Study Literature Review / Gap ...

    Science.gov (United States)

    In order to more fully understand data gaps in human exposure and toxicity to tire crumb materials, ATSDR, CPSC and EPA undertook a collaborative effort in the form of a scientific literature review and subsequent gaps analysis. The first objective of the Literature Review and Gap Analysis (LRGA) collaboration was to identify the existing body of literature related specifically to human exposure to tire crumb materials through the use of synthetic turf athletic fields and playgrounds. The second objective was to characterize and summarize the relevant data from the scientific literature. The final objective was to review the summary information and identify data gaps to build on the current understanding of the state-of-the-science and inform the development of specific research efforts that would be most impactful in the near-term. Because of the need for additional information, the U.S. Environmental Protection Agency (EPA), the Centers for Disease Control and Prevention/Agency for Toxic Substances and Disease Registry (ATSDR), and the U.S. Consumer Product Safety Commission (CPSC) launched a multi-agency action plan to study key environmental human health questions. The Federal Research Action Plan includes numerous activities, including research studies (U.S. EPA, 2016). A key objective of the Action Plan is to identify key knowledge gaps.

  17. Radiological research in Europe: a bibliometric study

    International Nuclear Information System (INIS)

    Mela, G.S.; Martinoli, C.; Poggi, E.; Derchi, L.E.

    2003-01-01

    . Although not flawless, and often criticized for a variety of reasons, citation analysis is a commonly used technique in this field, is a frequent means to ''weight'' the scientific production of researchers and is one of the criteria used to assign research grants. Our study shows that European radiology is growing and its production is increasing over time, thus indicating strong commitment to research from European radiologists; however, European radiological research has not yet reached leadership in the literature, and mean indexes addressing the level of resources allocated to research are lower in Europe than in the U.S. This latter point has notable exceptions, but indicates inadequacy of funding, at least in some nations, and in Europe as a whole. The development of research programs within the framework of the European Union specifically aimed to radiology could lead to further advancement of our discipline. (orig.)

  18. Program for transfer research and impact studies

    Science.gov (United States)

    Rusnak, J. J.; Freeman, J. E.; Hartley, J. M.; Kottenstette, J. P.; Staskin, E. R.

    1973-01-01

    Research activities conducted under the Program for Transfer Research and Impact Studies (TRIS) during 1972 included: (1) preparation of 10,196 TSP requests for TRIS application analysis; (2) interviews with over 500 individuals concerning the technical, economic, and social impacts of NASA-generated technology; (3) preparation of 38 new technology transfer example files and 101 new transfer cases; and (4) maintenance of a technology transfer library containing more than 2,900 titles. Six different modes of technology utilization are used to illustrate the pervasiveness of the transfer and diffusion of aerospace innovations. These modes also provide a basis for distinguishing the unique characteristics of the NASA Technology Utilization Program. An examination is reported of the ways in which NASA-generated technology is contributing to beneficial social change in five major areas of human concern: health, environment, safety, transportation, and communication.

  19. Mapping Translation Technology Research in Translation Studies

    DEFF Research Database (Denmark)

    Schjoldager, Anne; Christensen, Tina Paulsen; Flanagan, Marian

    2017-01-01

    section aims to improve this situation by presenting new and innovative research papers that reflect on recent technological advances and their impact on the translation profession and translators from a diversity of perspectives and using a variety of methods. In Section 2, we present translation......Due to the growing uptake of translation technology in the language industry and its documented impact on the translation profession, translation students and scholars need in-depth and empirically founded knowledge of the nature and influences of translation technology (e.g. Christensen....../Schjoldager 2010, 2011; Christensen 2011). Unfortunately, the increasing professional use of translation technology has not been mirrored within translation studies (TS) by a similar increase in research projects on translation technology (Munday 2009: 15; O’Hagan 2013; Doherty 2016: 952). The current thematic...

  20. Peer Assisted Study Sessions for Research Trainees

    Science.gov (United States)

    Cusick, Anne; Camer, Danielle; Stamenkovic, Alexander; Zaccagnini, Melissa

    2015-01-01

    Research training should facilitate effective researcher role development. While researcher roles require the performance of specialised knowledge and skill, they also require development of personal research identities within social contexts. Interaction with research peers can provide opportunities for reflective role development. Ad-hoc…

  1. Building theories from case study research: the progressive case study

    NARCIS (Netherlands)

    Steenhuis, H.J.; de Bruijn, E.J.

    2006-01-01

    Meredith (1998) argues for more case and field research studies in the field of operations management. Based on a literature review, we discuss several existing approaches to case studies and their characteristics. These approaches include; the Grounded Theory approach which proposes no prior

  2. In situ stress determination research study

    International Nuclear Information System (INIS)

    Austin, W.G.; Thompson, P.M.

    1994-01-01

    The objectives of this study are to evaluate and implement rock stress determination instruments and techniques developed by Atomic Energy of Canada Limited (AECL) at its Underground Research Laboratory (URL) for use in jointed rock and to continue the development of analytical and interpretation methods for stress determination results including effects of scale, structure and anisotropy. Testing and evaluation of the instruments and methods developed at URL need to be done in a similar rock type prior to underground access at the Yucca Mountain Site Characterization Project

  3. SVM-Prot 2016: A Web-Server for Machine Learning Prediction of Protein Functional Families from Sequence Irrespective of Similarity.

    Science.gov (United States)

    Li, Ying Hong; Xu, Jing Yu; Tao, Lin; Li, Xiao Feng; Li, Shuang; Zeng, Xian; Chen, Shang Ying; Zhang, Peng; Qin, Chu; Zhang, Cheng; Chen, Zhe; Zhu, Feng; Chen, Yu Zong

    2016-01-01

    Knowledge of protein function is important for biological, medical and therapeutic studies, but many proteins are still unknown in function. There is a need for more improved functional prediction methods. Our SVM-Prot web-server employed a machine learning method for predicting protein functional families from protein sequences irrespective of similarity, which complemented those similarity-based and other methods in predicting diverse classes of proteins including the distantly-related proteins and homologous proteins of different functions. Since its publication in 2003, we made major improvements to SVM-Prot with (1) expanded coverage from 54 to 192 functional families, (2) more diverse protein descriptors protein representation, (3) improved predictive performances due to the use of more enriched training datasets and more variety of protein descriptors, (4) newly integrated BLAST analysis option for assessing proteins in the SVM-Prot predicted functional families that were similar in sequence to a query protein, and (5) newly added batch submission option for supporting the classification of multiple proteins. Moreover, 2 more machine learning approaches, K nearest neighbor and probabilistic neural networks, were added for facilitating collective assessment of protein functions by multiple methods. SVM-Prot can be accessed at http://bidd2.nus.edu.sg/cgi-bin/svmprot/svmprot.cgi.

  4. Cellular transport of lutein is greater from uncooked rather than cooked spinach irrespective of whether it is fresh, frozen, or canned.

    Science.gov (United States)

    O'Sullivan, Laurie; Ryan, Lisa; Aherne, S Aisling; O'Brien, Nora M

    2008-08-01

    Lutein, a carotenoid found in significant levels in spinach, has attracted a great deal of attention owing to its reported function as a shield against the photooxidative effects of blue light. Therefore, the rationale of this study was to examine the effects of various processing and cooking methods on lutein bioavailability from spinach (Spinacia oleracea) using an in vitro digestion procedure coupled with the use of a human intestinal Caco-2 cell model. Fresh, frozen, and canned spinach were analyzed uncooked and after boiling or microwave cooking. Lutein content from the uncooked and cooked digested food (digestate) and appropriate micelles was determined. Micellarized lutein from the spinach samples was adjusted to 0.1 micromol/L and added to Caco-2 cells. Cellular uptake and secretion (cellular transport) of lutein were determined. Our results showed that digestate obtained from uncooked canned spinach had greater lutein content (P canned spinach digestate and micelles compared with their uncooked counterparts. Interestingly, there were no differences in the micellarization of lutein between the cooking and processing methods. Cellular transport of lutein was greater from uncooked spinach micelles compared with boiled or microwave-cooked spinach. To conclude, although the lutein content of digesta and micelles may have been modified, its micellarization was not significantly affected by any of the cooking or processing methods tested. In general, cellular transport of lutein was greatest in uncooked spinach irrespective of whether the spinach was fresh, frozen, or canned.

  5. Gram-positive and gram-negative bacteria induce different patterns of cytokine production in human mononuclear cells irrespective of taxonomic relatedness.

    Science.gov (United States)

    Skovbjerg, Susann; Martner, Anna; Hynsjö, Lars; Hessle, Christina; Olsen, Ingar; Dewhirst, Floyd E; Tham, Wilhelm; Wold, Agnes E

    2010-01-01

    Upon bacterial stimulation, tissue macrophages produce a variety of cytokines that orchestrate the immune response that clears the infection. We have shown that Gram-positives induce higher levels of interleukin-12 (IL-12), interferon-gamma (IFN-gamma), and tumor necrosis factor (TNF) from human peripheral blood mononuclear cells (PBMCs) than do Gram-negatives, which instead induce more of IL-6, IL-8, and IL-10. Here, we study whether these patterns follows or crosses taxonomic borders. PBMCs from blood donors were incubated with UV-inactivated bacteria representing 37 species from five phyla. IL-12, TNF, IL-1beta, IL-6, IL-8, and IL-10 were measured in the supernatants after 24 h and IFN-gamma after 5 days. Irrespective of phylogenetic position, Gram-positive bacteria induced much more IL-12 (nine times more on average) and IFN-gamma (seven times), more TNF (three times), and slightly more IL-1beta (1.5 times) than did Gram-negatives, which instead induced more IL-6 (1.5 times), IL-8 (1.9 times), and IL-10 (3.3 times) than did Gram-positives. A notable exception was the Gram-positive Listeria monocytogenes, which induced very little IL-12, IFN-gamma, and TNF. The results confirm the fundamental difference in innate immune responses to Gram-positive and Gram-negative bacteria, which crosses taxonomic borders and probably reflects differences in cell wall structure.

  6. Piperlongumine inhibits the proliferation and survival of B-cell acute lymphoblastic leukemia cell lines irrespective of glucocorticoid resistance

    Energy Technology Data Exchange (ETDEWEB)

    Han, Seong-Su, E-mail: seong-su-han@uiowa.edu [Division of Pediatric Hematology-Oncology, University of Iowa Carver College of Medicine, Iowa City, IA (United States); Han, Sangwoo [Health and Human Physiology, University of Iowa Carver College of Medicine, Iowa City, IA (United States); Kamberos, Natalie L. [Division of Pediatric Hematology-Oncology, University of Iowa Carver College of Medicine, Iowa City, IA (United States)

    2014-09-26

    Highlights: • PL inhibits the proliferation of B-ALL cell lines irrespective of GC-resistance. • PL selectively kills B-ALL cells by increasing ROS, but not normal counterpart. • PL does not sensitize majority of B-ALL cells to DEX. • PL represses the network of constitutively activated TFs and modulates their target genes. • PL may serve as a new therapeutic molecule for GC-resistant B-ALL. - Abstract: Piperlongumine (PL), a pepper plant alkaloid from Piper longum, has anti-inflammatory and anti-cancer properties. PL selectively kills both solid and hematologic cancer cells, but not normal counterparts. Here we evaluated the effect of PL on the proliferation and survival of B-cell acute lymphoblastic leukemia (B-ALL), including glucocorticoid (GC)-resistant B-ALL. Regardless of GC-resistance, PL inhibited the proliferation of all B-ALL cell lines, but not normal B cells, in a dose- and time-dependent manner and induced apoptosis via elevation of ROS. Interestingly, PL did not sensitize most of B-ALL cell lines to dexamethasone (DEX). Only UoC-B1 exhibited a weak synergistic effect between PL and DEX. All B-ALL cell lines tested exhibited constitutive activation of multiple transcription factors (TFs), including AP-1, MYC, NF-κB, SP1, STAT1, STAT3, STAT6 and YY1. Treatment of the B-ALL cells with PL significantly downregulated these TFs and modulated their target genes. While activation of AURKB, BIRC5, E2F1, and MYB mRNA levels were significantly downregulated by PL, but SOX4 and XBP levels were increased by PL. Intriguingly, PL also increased the expression of p21 in B-ALL cells through a p53-independent mechanism. Given that these TFs and their target genes play critical roles in a variety of hematological malignancies, our findings provide a strong preclinical rationale for considering PL as a new therapeutic agent for the treatment of B-cell malignancies, including B-ALL and GC-resistant B-ALL.

  7. Piperlongumine inhibits the proliferation and survival of B-cell acute lymphoblastic leukemia cell lines irrespective of glucocorticoid resistance

    International Nuclear Information System (INIS)

    Han, Seong-Su; Han, Sangwoo; Kamberos, Natalie L.

    2014-01-01

    Highlights: • PL inhibits the proliferation of B-ALL cell lines irrespective of GC-resistance. • PL selectively kills B-ALL cells by increasing ROS, but not normal counterpart. • PL does not sensitize majority of B-ALL cells to DEX. • PL represses the network of constitutively activated TFs and modulates their target genes. • PL may serve as a new therapeutic molecule for GC-resistant B-ALL. - Abstract: Piperlongumine (PL), a pepper plant alkaloid from Piper longum, has anti-inflammatory and anti-cancer properties. PL selectively kills both solid and hematologic cancer cells, but not normal counterparts. Here we evaluated the effect of PL on the proliferation and survival of B-cell acute lymphoblastic leukemia (B-ALL), including glucocorticoid (GC)-resistant B-ALL. Regardless of GC-resistance, PL inhibited the proliferation of all B-ALL cell lines, but not normal B cells, in a dose- and time-dependent manner and induced apoptosis via elevation of ROS. Interestingly, PL did not sensitize most of B-ALL cell lines to dexamethasone (DEX). Only UoC-B1 exhibited a weak synergistic effect between PL and DEX. All B-ALL cell lines tested exhibited constitutive activation of multiple transcription factors (TFs), including AP-1, MYC, NF-κB, SP1, STAT1, STAT3, STAT6 and YY1. Treatment of the B-ALL cells with PL significantly downregulated these TFs and modulated their target genes. While activation of AURKB, BIRC5, E2F1, and MYB mRNA levels were significantly downregulated by PL, but SOX4 and XBP levels were increased by PL. Intriguingly, PL also increased the expression of p21 in B-ALL cells through a p53-independent mechanism. Given that these TFs and their target genes play critical roles in a variety of hematological malignancies, our findings provide a strong preclinical rationale for considering PL as a new therapeutic agent for the treatment of B-cell malignancies, including B-ALL and GC-resistant B-ALL

  8. CSM research: Methods and application studies

    Science.gov (United States)

    Knight, Norman F., Jr.

    1989-01-01

    Computational mechanics is that discipline of applied science and engineering devoted to the study of physical phenomena by means of computational methods based on mathematical modeling and simulation, utilizing digital computers. The discipline combines theoretical and applied mechanics, approximation theory, numerical analysis, and computer science. Computational mechanics has had a major impact on engineering analysis and design. When applied to structural mechanics, the discipline is referred to herein as computational structural mechanics. Complex structures being considered by NASA for the 1990's include composite primary aircraft structures and the space station. These structures will be much more difficult to analyze than today's structures and necessitate a major upgrade in computerized structural analysis technology. NASA has initiated a research activity in structural analysis called Computational Structural Mechanics (CSM). The broad objective of the CSM activity is to develop advanced structural analysis technology that will exploit modern and emerging computers, such as those with vector and/or parallel processing capabilities. Here, the current research directions for the Methods and Application Studies Team of the Langley CSM activity are described.

  9. International Study of Chaplains' Attitudes About Research.

    Science.gov (United States)

    Snowden, Austyn; Fitchett, George; Grossoehme, Daniel H; Handzo, George; Kelly, Ewan; King, Stephen D W; Telfer, Iain; Tan, Heather; Flannelly, Kevin J

    2017-01-01

    An online survey was conducted by twelve professional chaplain organizations to assess chaplains' attitudes about and involvement in research. A total of 2,092 chaplains from 23 countries responded to the survey. Over 80% thought research was definitely important and nearly 70% thought chaplains should definitely be research literate. Just over 40% said they regularly read research articles and almost 60% said they occasionally did. The respondents rated their own research literacy as 6.5 on a 0-10 scale. Significant positive inter-correlations were found among all four measures: importance of (a) research and (b) research literacy; (c) frequency of reading articles; and (d) research literacy rating. Approximately 35% were never involved, 37% had been involved, 17% were currently involved, and 11% expected to be involved in research. The last three groups were significantly more likely to think research and research literacy were important and to read research articles than chaplains who were never involved in research. Given chaplains' interest in research, actions should be undertaken to facilitate further research engagement.

  10. Qualitative research in travel behavior studies

    Energy Technology Data Exchange (ETDEWEB)

    Mars Aicart, M.L.; Ruiz Sanchez, T.; Arroyo Lopez, M.R.

    2016-07-01

    Qualitative methodology is extensively used in a wide range of scientific areas, such as Sociology and Psychology, and it is been used to study individual and household decision making processes. However, in the Transportation Planning and Engineering domain it is still infrequent to find in the travel behavior literature studies using qualitative techniques to explore activity-travel decisions. The aim of this paper is first, to provide an overview of the types of qualitative techniques available and to explore how to correctly implement them. Secondly, to highlight the special characteristics of qualitative methods that make them appropriate to study activity-travel decision processes. Far from been an unempirical or intuitive methodology, using qualitative methods properly implies a strong foundation on theoretical frameworks, a careful design of data collection and a deep data analysis. For such a purpose, a review of the scarce activity-travel behavior literature using qualitative methods, or a combination of qualitative and quantitative approaches, is presented. The use of qualitative techniques can play a role of being a supplementary way of obtaining information related to activity-travel decisions which otherwise it would be extremely difficult to find. This work ends with some conclusions about how qualitative research could help in making progress on activity-travel behavior studies. (Author)

  11. Research Map of Research Priorities in HE Studies in the Kingdom of Saudi Arabia

    Science.gov (United States)

    AlSumih, A. M.

    2016-01-01

    This study presents a research map for the key research priorities of higher education (HE) in the Kingdom of Saudi Arabia. The study diagnoses and analyzes the research reality in HE studies in KSA in terms of strength points and improvement opportunities. It also explores the research map fields of current and prospective research priorities in…

  12. Internal NASA Study: NASAs Protoflight Research Initiative

    Science.gov (United States)

    Coan, Mary R.; Hirshorn, Steven R.; Moreland, Robert

    2015-01-01

    The NASA Protoflight Research Initiative is an internal NASA study conducted within the Office of the Chief Engineer to better understand the use of Protoflight within NASA. Extensive literature reviews and interviews with key NASA members with experience in both robotic and human spaceflight missions has resulted in three main conclusions and two observations. The first conclusion is that NASA's Protoflight method is not considered to be "prescriptive." The current policies and guidance allows each Program/Project to tailor the Protoflight approach to better meet their needs, goals and objectives. Second, Risk Management plays a key role in implementation of the Protoflight approach. Any deviations from full qualification will be based on the level of acceptable risk with guidance found in NPR 8705.4. Finally, over the past decade (2004 - 2014) only 6% of NASA's Protoflight missions and 6% of NASA's Full qualification missions experienced a publicly disclosed mission failure. In other words, the data indicates that the Protoflight approach, in and of it itself, does not increase the mission risk of in-flight failure. The first observation is that it would be beneficial to document the decision making process on the implementation and use of Protoflight. The second observation is that If a Project/Program chooses to use the Protoflight approach with relevant heritage, it is extremely important that the Program/Project Manager ensures that the current project's requirements falls within the heritage design, component, instrument and/or subsystem's requirements for both the planned and operational use, and that the documentation of the relevant heritage is comprehensive, sufficient and the decision well documented. To further benefit/inform this study, a recommendation to perform a deep dive into 30 missions with accessible data on their testing/verification methodology and decision process to research the differences between Protoflight and Full Qualification

  13. Leading with integrity: a qualitative research study.

    Science.gov (United States)

    Storr, Loma

    2004-01-01

    This research paper gives an account of a study into the relationship between leadership and integrity. There is a critical analysis of the current literature for effective, successful and ethical leadership particularly, integrity. The purpose and aim of this paper is to build on the current notions of leadership within the literature, debate contemporary approaches, focussing specifically on practices within the UK National Health Service in the early 21st century. This leads to a discussion of the literature on ethical leadership theory, which includes public service values, ethical relationships and leading with integrity. A small study was undertaken consisting of 18 interviews with leaders and managers within a District General HospitaL Using the Repertory Grid technique and analysis 15 themes emerged from the constructs elicited, which were compared to the literature for leadership and integrity and other studies. As well as finding areas of overlap, a number of additional constructs were elicited which suggested that effective leadership correlates with integrity and the presence of integrity will improve organisational effectiveness. The study identified that perceptions of leadership character and behaviour are used to judge the effectiveness and integrity of a leader. However, the ethical implications and consequences of leaders' scope of power and influence such as policy and strategy are somewhat neglected and lacking in debate. The findings suggest that leaders are not judged according to the ethical nature of decision making, and leading and managing complex change but that the importance of integrity and ethical leadership correlated with higher levels of hierarchical status and that it is assumed by virtue of status and success that leaders lead with integrity. Finally, the findings of this study seem to suggest that nurse leadership capability is developing as a consequence of recent national investment.

  14. High prevalence of abnormalities on CT and MR imaging in children with unilateral sensorineural hearing loss irrespective of age or degree of hearing loss.

    Science.gov (United States)

    van Beeck Calkoen, E A; Sanchez Aliaga, E; Merkus, P; Smit, C F; van de Kamp, J M; Mulder, M F; Goverts, S T; Hensen, E F

    2017-06-01

    Evaluation of causal abnormalities identified on CT and MR imaging in children with unilateral sensorineural hearing loss (USNHL), and the association with age and severity of hearing loss. Retrospective cohort study. Tertiary referral otology/audiology center. 102 children diagnosed with USNHL between 2006 and 2016 were included. They underwent CT and/or MR imaging for the evaluation of the etiology of their hearing loss. Radiologic abnormalities of the inner ear and brain associated with USNHL. Using CT and/or MR imaging, causal abnormalities were identified in 49%, which is higher than previously reported (25-40%). The most frequently affected site was the labyrinth (29%), followed by the cochlear nerve (9%) and brain (7%). No significant difference in the number or type of abnormalities was found for the degree of hearing loss or age categories. Imaging is essential in the etiologic analysis of USNHL because of the high prevalence of causative abnormalities that can be identified with radiology, irrespective of the patients' age or degree of hearing loss. CT and MR imaging are complementary imaging options. The ideal imaging algorithm is controversial. Based on our findings, we conclude that there is limited additional diagnostic value of simultaneous dual modality imaging over sequential diagnostics. We therefore perform a stepwise radiological workup in order to maximize the diagnostic yield while minimizing impact and costs. If the primary imaging modality does not identify a cause for USNHL, performing the alternative imaging modality should be considered. Retrospective cohort study 2b. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Colorectal Surgery Fellowship Improves In-hospital Mortality After Colectomy and Proctectomy Irrespective of Hospital and Surgeon Volume.

    Science.gov (United States)

    Saraidaridis, Julia T; Hashimoto, Daniel A; Chang, David C; Bordeianou, Liliana G; Kunitake, Hiroko

    2018-03-01

    General surgery residents are increasingly pursuing sub-specialty training in colorectal (CR) surgery. However, the majority of operations performed by CR surgeons are also performed by general surgeons. This study aimed to assess in-hospital mortality stratified by CR training status after adjusting for surgeon and hospital volume. The Statewide Planning and Research Cooperative system database was used to identify all patients who underwent colectomy/proctectomy from January 1, 2000, to December 31, 2014, in the state of New York. Operations performed by board-certified CR surgeons were identified. The relationships between CR board certification and in-hospital mortality, in-hospital complications, length of stay, and ostomy were assessed using multivariate regression models. Two hundred seventy thousand six hundred eighty-four patients underwent colectomy/proctectomy over the study period. Seventy-two thousand two hundred seventy-nine (26.7%) of operations were performed by CR surgeons. Without adjusting for hospital and surgeon volume, in-hospital mortality was lower for those undergoing colectomy/proctectomy by a CR surgeon (OR 0.49, CI 0.44-0.54, p = 0.001). After controlling for hospital and surgeon volume, the odds of inpatient mortality after colectomy/proctectomy for those operated on by CR surgeons weakened to 0.76 (CI 0.68-0.86, p = 0.001). Hospital and surgeon volume accounted for 53% of the reduction in in-hospital mortality when CR surgeons performed colectomy/proctectomy. Patients who underwent surgery by a CR surgeon had a shorter inpatient stay (0.8 days, p = 0.001) and a decreased chance of colostomy (OR 0.86, CI 0.78-0.95, p accounting for hospital and surgeon volume.

  16. Dance Education Action Research: A Twin Study

    Science.gov (United States)

    Giguere, Miriam

    2015-01-01

    In this article, the author compares the practices, philosophy, and history of action research, also known as participatory action research, to the purposes and practices of dance education. The comparison yields connections in four categories, enhancing self-reflective teaching and curriculum design, taking responsibility for teaching outcomes,…

  17. Food studies: an introduction to research methods

    National Research Council Canada - National Science Library

    Miller, Jeff; Deutsch, Jonathan

    2009-01-01

    .... Designed for the classroom as well as for the independent scholar, the book details the predominant research methods in the field, provides a series of interactive questions and templates to help...

  18. Intervention Studies in Suicide Prevention Research

    NARCIS (Netherlands)

    Huisman, A.; Pirkis, J; Robinson, J.

    2010-01-01

    Background: Despite the growing strength of the field of suicidology, various commentators have recently noted that insufficient effort is being put into intervention research, and that this is limiting our knowledge of which suicide prevention strategies might be the most effective. Aims: To

  19. Case study of information product for strategy research, planning research, and policy research

    International Nuclear Information System (INIS)

    Yuan Yujun; Zou Lin; Liu Qun; Wang Yongping

    2010-01-01

    Soft science research is significant and can directly support the decision-making and development. The strategy research, planning research, and policy research each play an important role in soft science research. As the National Strategy of Informatization being implemented and advanced, some progress are made and some special information tools are produced in the process of strengthening the development research with information technologies. At first, the article introduced some cases of information products application, such as the domestic and overseas information products for energy strategy research and planning research and policy research, the governmental management information system for planning and investment, examination and approval and permission system for the planning of the land for construction, China agriculture decision support system and so on, and also gave a brief analysis on the theories and methods, main functions and application status. And then, with a analysis on the features of the works of development planning of China National Nuclear Corporation (CNNC) development, this article gave some suggestions on how to strengthen the development of information system for the development planning of the CNNC. (authors)

  20. [Strengthening the methodology of study designs in scientific researches].

    Science.gov (United States)

    Ren, Ze-qin

    2010-06-01

    Many problems in study designs have affected the validity of scientific researches seriously. We must understand the methodology of research, especially clinical epidemiology and biostatistics, and recognize the urgency in selection and implement of right study design. Thereafter we can promote the research capability and improve the overall quality of scientific researches.

  1. Student Voice in High School: An Action Research Study

    Science.gov (United States)

    Termini, Lorraine

    2013-01-01

    This action research study examined the effects of student voice in one high school and the self-reflection of the researcher-administrator involved in the effort. Using three cycles of action research, the researcher-administrator completed a pilot study, implemented a student voice project in one class, and developed a professional development…

  2. Studies of the CNESTEN's Nuclear Research Centre

    International Nuclear Information System (INIS)

    Alami, R.

    1988-11-01

    The different steps of the methodology applied to the site selection of Maamora's Nuclear Research Centre, within a 20 km wide coastal band preliminarily fixed between Kenitra and Casablanca cities, are outlined: delimitation of potential zones, identification of potential sites, selection of preferred sites. A particular attention is given to the criterium of the methodology applied to the preferred sites classifying. 1 map, 2 tabs, 2 refs. (F.M.)

  3. Case Studies Approach in Tourism Destination Branding Research

    OpenAIRE

    Adeyinka-Ojo S.F.; Nair V.; Khoo-Lattimore C.

    2014-01-01

    A review of literature indicates that there are different types of qualitative research methods such as action research, content analysis, ethnography, grounded theory, historical analysis, phenomenology and case study. However, which approach is to be used depends on several factors such as the nature and objectives of the research. The aim of this paper is to focus on the research methodology aspects of applying case study as a research approach and its relevance in tourism destination bran...

  4. Research progress in study of accidental hypothermia

    Directory of Open Access Journals (Sweden)

    Rui YUAN

    2016-04-01

    Full Text Available Accidental hypothermia refers to a state of lowering of core body temperature down to 35 ℃induced by drowning, burial in snow and prolonged exposure to cold environment, etc. Hypothermia may affect the cardiovascular system, respiratory system, digestive system, etc. The triad consisting "hypothermia, acidosis and coagulopathy" is an important factor accelerating the death of patients. Early, timely application of rewarming measures is regarded as the basic principle in treatment of hypothermia. A series of rewarming measures, such as infusion of warm fluids, inspiration of warm air, abdominal infusion of warm fluid, instruction of warm fluid into pleural cavity, intravenous infusion of warm fluid, rewarming through ECMO, etc. have been used recently. Advance in research on the classification of hypothermia, its impact to the body and the treatment methods are reviewed in present paper. DOI: 10.11855/j.issn.0577-7402.2016.04.15

  5. Recruitment to Intellectual Disability Research: A Qualitative Study

    Science.gov (United States)

    Nicholson, L.; Colyer, M.; Cooper, S. -A.

    2013-01-01

    Background: Difficulties in the recruitment of adults with intellectual disability (ID) to research studies are well described but little studied. The aim of this study was to investigate the difficulties in recruiting to a specific research project, in order to inform future recruitment to ID research. Methods: Individual semi-structured…

  6. History Through Biography? A Conceptual Research Study.

    Science.gov (United States)

    Johns, Robert W.

    Social studies classroom teachers can enliven high school history courses and motivate students to learn about history by using dramatic or heroic biographies in teaching history. The biographical approach centers on study of the lives, beliefs, and surroundings of historical actors. This approach differs from the "great man" theory of history in…

  7. Collaborative Research: The Alphabetic Braille and Contracted Braille Study as an Example of Collaborative Research

    Science.gov (United States)

    Wormsley, Diane P.; Emerson, Robert Wall; Erin, Jane

    2011-01-01

    This article examines the Alphabetic Braille Contracted Braille Study in relation to the dimensions of collaborative research: extent, intensity, substance, heterogeneity, velocity, formality, and productivity. It also discusses the dimensions of financing research and researchers' attitudes. The overall consensus is that the study would not have…

  8. Technology teachers as researchers : philosophical and empirical technology education studies in the Swedish TUFF Research School

    NARCIS (Netherlands)

    Skogh, I.B.; Vries, de M.J.

    2013-01-01

    This book presents the scientific output of the TUFF research school in Sweden. In this school, a group of active teachers worked together on a series of educational research studies. All of those studies were related to the teaching about technology and engineering. The research program consisted

  9. Empirical Scientific Research and Legal Studies Research--A Missing Link

    Science.gov (United States)

    Landry, Robert J., III

    2016-01-01

    This article begins with an overview of what is meant by empirical scientific research in the context of legal studies. With that backdrop, the argument is presented that without engaging in normative, theoretical, and doctrinal research in tandem with empirical scientific research, the role of legal studies scholarship in making meaningful…

  10. Cooperative Research Twin Trawl Sweep Comparison Study

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The "Twin-Trawl Sweep Efficiency Study" was intended to compare the sweep efficiency and selectivity of the NEFSC standardized bottom trawl to that of a standardized...

  11. Case Study Observational Research: A Framework for Conducting Case Study Research Where Observation Data Are the Focus.

    Science.gov (United States)

    Morgan, Sonya J; Pullon, Susan R H; Macdonald, Lindsay M; McKinlay, Eileen M; Gray, Ben V

    2017-06-01

    Case study research is a comprehensive method that incorporates multiple sources of data to provide detailed accounts of complex research phenomena in real-life contexts. However, current models of case study research do not particularly distinguish the unique contribution observation data can make. Observation methods have the potential to reach beyond other methods that rely largely or solely on self-report. This article describes the distinctive characteristics of case study observational research, a modified form of Yin's 2014 model of case study research the authors used in a study exploring interprofessional collaboration in primary care. In this approach, observation data are positioned as the central component of the research design. Case study observational research offers a promising approach for researchers in a wide range of health care settings seeking more complete understandings of complex topics, where contextual influences are of primary concern. Future research is needed to refine and evaluate the approach.

  12. Feed process studies: Research-Scale Melter

    Energy Technology Data Exchange (ETDEWEB)

    Whittington, K.F.; Seiler, D.K.; Luey, J.; Vienna, J.D.; Sliger, W.A.

    1996-09-01

    In support of a two-phase approach to privatizing the processing of hazardous and radioactive waste at Hanford, research-scale melter (RSM) experiments were conducted to determine feed processing characteristics of two potential privatization Phase 1 high-level waste glass formulations and to determine if increased Ag, Te, and noble metal amounts would have bad effects. Effects of feed compositions and process conditions were examined for processing rate, cold cap behavior, off-gas, and glass properties. The 2 glass formulations used were: NOM-2 with adjusted waste loading (all components except silica and soda) of 25 wt%, and NOM-3 (max waste loaded glass) with adjusted waste loading of 30 wt%. The 25 wt% figure is the minimum required in the privatization Request for Proposal. RSM operated for 19 days (5 runs). 1010 kg feed was processed, producing 362 kg glass. Parts of runs 2 and 3 were run at 10 to 30 degrees above the nominal temperature 1150 C, with the most significant processing rate increase in run 3. Processing observations led to the choice of NOM-3 for noble metal testing in runs 4 and 5. During noble metal testing, processing rates fell 50% from baseline. Destructive analysis showed that a layer of noble metals and noble metal oxides settled on the floor of the melter, leading to current ``channeling`` which allowed the top section to cool, reducing production rates.

  13. Feed process studies: Research-Scale Melter

    International Nuclear Information System (INIS)

    Whittington, K.F.; Seiler, D.K.; Luey, J.; Vienna, J.D.; Sliger, W.A.

    1996-09-01

    In support of a two-phase approach to privatizing the processing of hazardous and radioactive waste at Hanford, research-scale melter (RSM) experiments were conducted to determine feed processing characteristics of two potential privatization Phase 1 high-level waste glass formulations and to determine if increased Ag, Te, and noble metal amounts would have bad effects. Effects of feed compositions and process conditions were examined for processing rate, cold cap behavior, off-gas, and glass properties. The 2 glass formulations used were: NOM-2 with adjusted waste loading (all components except silica and soda) of 25 wt%, and NOM-3 (max waste loaded glass) with adjusted waste loading of 30 wt%. The 25 wt% figure is the minimum required in the privatization Request for Proposal. RSM operated for 19 days (5 runs). 1010 kg feed was processed, producing 362 kg glass. Parts of runs 2 and 3 were run at 10 to 30 degrees above the nominal temperature 1150 C, with the most significant processing rate increase in run 3. Processing observations led to the choice of NOM-3 for noble metal testing in runs 4 and 5. During noble metal testing, processing rates fell 50% from baseline. Destructive analysis showed that a layer of noble metals and noble metal oxides settled on the floor of the melter, leading to current ''channeling'' which allowed the top section to cool, reducing production rates

  14. Navigating political minefields: partnerships in organizational case study research.

    Science.gov (United States)

    Moll, Sandra

    2012-01-01

    The purpose of this paper is to examine key challenges associated with conducting politically sensitive research within a workplace setting, and to highlight strategic partnerships that can be developed to address these challenges. The author's research on employee mental health issues within a large healthcare facility serves as the foundation for identification and description of "political minefields" that investigators may encounter when conducting organizational case study research. Key methodological principles from the literature on qualitative case study research will frame discussion of how to understand and address political sensitivities in the research process. The benefits of conducting organizational case study research will be outlined, followed by discussion of methodological challenges that can emerge in negotiating entry, collecting data (gatekeepers, researcher reflexivity, participant authenticity and non-maleficence), and communicating research findings. Courage, collaboration and clear communication with stakeholders at all levels of the organization are critical to the success of workplace based case study research.

  15. Transversal Traits in Science Education Research Relevant for Teaching and Research: A Meta-Interpretative Study

    Science.gov (United States)

    Lopes, J. Bernardino; Silva, Antonio Alberto; Cravino, Jose P.; Costa, Nilza; Marques, Luis; Campos, Carlos

    2008-01-01

    This study is a meta-interpretative analysis that focuses on research conducted and published by other researchers. Concepts central to this study include global practical relevance, curriculum design, and formative situation. We analyzed 35 studies selected from 374 published studies in the years 2000 and 2001 in three journals referenced in the…

  16. Oxytocin reduces amygdala activity, increases social interactions, and reduces anxiety-like behavior irrespective of NMDAR antagonism.

    Science.gov (United States)

    Sobota, Rosanna; Mihara, Takuma; Forrest, Alexandra; Featherstone, Robert E; Siegel, Steven J

    2015-08-01

    Standard dopamine therapies for schizophrenia are not efficacious for negative symptoms of the disease, including asociality. This reduced social behavior may be due to glutamatergic dysfunction within the amygdala, leading to increased fear and social anxiety. Several studies have demonstrated the prosocial effects of oxytocin in schizophrenia patients. Therefore, this study evaluates the effect of subchronic oxytocin on EEG activity in amygdala of mice during performance of the three-chamber social choice and open field tests following acute ketamine as a model of glutamatergic dysfunction. Oxytocin did not restore social deficits introduced by ketamine but did significantly increase sociality in comparison to the control group. Ketamine had no effect on time spent in the center during the open field trials, whereas oxytocin increased overall center time across all groups, suggesting a reduction in anxiety. Amygdala activity was consistent across all drug groups during social and nonsocial behavioral trials. However, oxytocin reduced overall amygdala EEG power during the two behavioral tasks. Alternatively, ketamine did not significantly affect EEG power throughout the tasks. Decreased EEG power in the amygdala, as caused by oxytocin, may be related to both reduced anxiety and increased social behaviors. Data suggest that separate prosocial and social anxiety pathways may mediate social preference. (c) 2015 APA, all rights reserved).

  17. Accelerator research studies: Annual progress report

    International Nuclear Information System (INIS)

    1988-01-01

    Our major goal in this experiment is to study the physics of a space-charge dominated beam propagating through a long, periodic transport channel consisting in our case of 38 solenoid lenses two of which are being used to match the beam from the gun into the periodic lattice. In addition, a small separate test stand gives us the capability of studying different electron gun designs including measurements of beam perveance and emittance, beam propagation in drift space and through a single solenoid lens. Most of our transport studies in the periodic channel have been conducted with a 5 keV, 200 mA electron beam from a gun with a 1-inch diameter thermionic cathode. The beam physics phenomena of greatest interest are instabilities due to resonant interaction between the beam and the periodic lattice, non-linear effects due to external forces (e.g., spherical lens aberrations) or due to nonuniform charge distributions, beam off-centering and misalignments which also include the effects of image forces. In principle, all of these effects may lead to emittance growth and beam loss. An important question is whether there exists a ''window'' of 100% transmission and minimal emittance growth in such a long periodic channel. 28 refs

  18. Adult Health Study: provisional research plan

    Energy Technology Data Exchange (ETDEWEB)

    Hollingsworth, J W; Beebe, G W

    1960-12-14

    The study is planned as an intensive search for the late effects of single, whole-body radiation from the Hiroshima and Nagasaki bombs. Although dosimetry information is by no means definitive at this time, preliminary information suggests that the effects of radiation doses up to 600 rads can be effectively studied in the surviving samples. The lower limit is moot, depending on the magnitude of the effect produced and the sensitivity of the study. The upper limit is also somewhat uncertain, as the most closely exposed individuals were more often heavily shielded. The potential radiation effects may be classified as follows: (1) alterations in the incidence of disease; (2) alterations in the natural history of disease, with or without alteration in incidence; (3) development of physiological or biochemical changes, or markers, short of actual disease; (4) nonspecific changes in vigor, acceleration of aging; and (5) occurrence of new diseases. It is proposed to conduct a search sufficiently intensive to detect effects of all five types. It is also a specific objective of this investigation to illuminate the pathogenesis of diseases of increased incidence, or of new diseases, if such be found. Also of interest is the matter of genetic or biochemical factors associated with survival and with the appearance of acute radiation symptoms. Survivors represent a truncated sample and selective host factors may have played a part in both survival and the liklihood of acute radiation symptoms. 17 reference.

  19. Guidelines for Conducting Positivist Case Study Research in Information Systems

    Directory of Open Access Journals (Sweden)

    Graeme Shanks

    2002-11-01

    Full Text Available The case study research approach is widely used in a number of different ways within the information systems community. This paper focuses on positivist, deductive case study research in information systems. It provides clear definitions of important concepts in positivist case study research and illustrates these with an example research study. A critical analysis of the conduct and outcomes of two recently published positivist case studies is reported. One is a multiple case study that validated concepts in a framework for viewpoint development in requirements definition. The other is a single case study that examined the role of social enablers in enterprise resource planning systems implementation. A number of guidelines for successfully undertaking positivist case study research are identified including developing a clear understanding of key concepts and assumptions within the positivist paradigm; providing clear and unambiguous definitions of the units and interactions when using any theory; carefully defining the boundary of the theory used in the case study; using hypotheses rather than propositions in the empirical testing of theory; using fuzzy or probabilistic propositions in recognising that reality can never be perfectly known; selecting case studies carefully, particularly single case studies; and recognising that generalisation from positivist, single case studies is inherently different from generalisation from single experiments. When properly undertaken, positivist, deductive case study research is a valuable research approach for information systems researchers, particularly when used within pluralist research programs that use a number of different research approaches from different paradigms.

  20. A Framework for Studying Organizational Innovation in Research Libraries

    Science.gov (United States)

    Jantz, Ronald C.

    2012-01-01

    The objective of this paper is two-fold: to propose a theoretical framework and model for studying organizational innovation in research libraries and to set forth propositions that can provide directions for future empirical studies of innovation in research libraries. Research libraries can be considered members of a class of organizations…

  1. Dramatic impact of blood transfusion on cancer-specific survival after radical cystectomy irrespective of tumor stage.

    Science.gov (United States)

    Buchner, Alexander; Grimm, Tobias; Schneevoigt, Birte-Swantje; Wittmann, Georg; Kretschmer, Alexander; Jokisch, Friedrich; Grabbert, Markus; Apfelbeck, Maria; Schulz, Gerald; Gratzke, Christian; Stief, Christian G; Karl, Alexander

    2017-04-01

    The aim of the present study was to determine the influence of intraoperative and postoperative blood transfusion on cancer-specific outcome. Follow-up data were collected from 722 patients undergoing radical cystectomy for urothelial carcinoma of the bladder (UCB) between 2004 and 2014. Median follow-up was 26 months (interquartile range 12-61 months). Outcome was analyzed in relation to the amount of intraoperative and postoperative blood transfusion and different tumor stages. The primary endpoint was cancer-specific survival (CSS) after cystectomy. Kaplan-Meier analysis with log-rank test and Cox regression models were used. Intraoperative blood transfusion was given in 36% (263/722) and postoperative blood transfusion in 18% (132/722). In patients with and without intraoperative blood transfusion, 5 year CSS was 48% and 67%, respectively (p blood transfusion, 5 year CSS was 48% and 63%, respectively (p transfused red blood cell (RBC) units [intraoperatively: hazard ratio (HR) = 1.08, 95% confidence interval (CI) 1.01-1.15, p = .023; postoperatively: HR = 1.14, 95% CI 1.07-1.21, p transfusions was also found in favorable subgroups (pT1 tumor, hemoglobin ≥13 mg/dl, p = .004) and in a high-volume surgeon subgroup (n = 244, p Blood transfusions during and after radical cystectomy were independent prognostic factors for CSS in this retrospective study. Therefore, efforts should be made to reduce the necessity of intraoperative and postoperative blood transfusion in cystectomy patients.

  2. Utilization of CT perfusion patient selection for mechanical thrombectomy irrespective of time: a comparison of functional outcomes and complications.

    Science.gov (United States)

    Turk, Aquilla S; Nyberg, Eric MacKenzie; Chaudry, M Imran; Turner, Raymond D; Magarik, Jordan Asher; Nicholas, Joyce S; Holmstedt, Christine A; Chalela, Julio Alejandro; Hays, Angela; Lazaridis, Christos; Chimowitz, Marc I; Turan, Tanya N; Adams, Robert J; Jauch, Edward C

    2013-11-01

    Patient selection for acute ischemic stroke has been largely driven by time-based criteria, although emerging data suggest that image-based criteria may be useful. The purpose of this study was to directly compare outcomes of patients treated within a traditional time window with those treated beyond this benchmark when CT perfusion (CTP) imaging was used as the primary selection tool. A prospectively collected database of all patients with acute ischemic stroke who received intra-arterial therapy at the Medical University of South Carolina was retrospectively analyzed, regardless of time from symptom onset. At presentation, CTP maps were qualitatively assessed. Selected patients underwent intra-arterial therapy. Functional outcome according to the modified Rankin scale (mRS) score at about 90 days was documented. 140 patients were included in the study. The median time from symptom onset to groin access was 7.0 h. Overall, 28 patients (20%) had bleeding complications, but only 10 (7.1%) were symptomatic. The average National Institute of Health Stroke Scale (NIHSS) score for patients treated ≤ 7 h from symptom onset was 17.3 and 30.2% had a mRS score of 0-2 at 90 days. Patients treated >7 h from symptom onset had an average NIHSS score of 15.1 and 45.5% achieved a mRS score of 0-2 at 90 days (p=0.104). Patients in the two groups had similar rates of symptomatic intracerebral hemorrhage (8.5% and 5.8%, respectively; p=0.745). No difference was found in the rates of good functional outcome between patients treated ≤ 7 h and those treated >7 h from symptom onset. These data suggest that imaging-based patient selection is a safe and viable methodology.

  3. Research Design in the study of the European Neighbourhood Policy

    DEFF Research Database (Denmark)

    Exadaktylos, Theofanis; Lynggaard, Kennet

    2017-01-01

    This chapter deals with the pitfalls and pathways of research design aimed at the study of the European Neighbourhood Policy (ENP) and maps out the literature on questions of knowledge ambition, research ontology and epistemology, and choices of approaches to the research object. We include...... a review of traditional research designs in ENP research, through a systematic meta-analysis of a selection of the most-cited articles on the ENP. Inspired by earlier work on awareness of research design in EU studies, ENP research is categorised according to typical choices of research design in the form...... of dichotomous trade-offs. The chapter then discusses how individual contributions to this volume deal with research design challenges of the past and present innovative ways of studying the revised ENP....

  4. 76 FR 40379 - New Proposed Collection; Comment Request; Study Logistic Formative Research Methodology Studies...

    Science.gov (United States)

    2011-07-08

    ...; Comment Request; Study Logistic Formative Research Methodology Studies for the National Children's Study... Collection Title: Study Logistics Formative Research Methodology Studies for the National Children's Study... national longitudinal study of environmental influences (including physical, chemical, biological, and...

  5. 1964 Project Springfield studies. Research Report 2

    International Nuclear Information System (INIS)

    Feteris, P.J.

    1975-10-01

    The analysis of the data for a storm on April 4, 1964, showed that in spite of all efforts to obtain a dynamically and internally consistent three-dimensional analysis of conventional wind, pressure, and temperature data, there remain ambiguities of 50 to 100 miles in the horizontal location of the boundaries of the stratospheric air. Missing wind data and temperature errors, though not disastrous in routine meteorological analysis, can seriously affect the potential vorticity computations for several isentropic surfaces. Trajectory analyses introduce additional errors. Aircraft measurements of fallout beta activity, when carefully planned and made at map time, can improve the precision to 1000 feet in the vertical, and to a few miles in the horizontal. This precision is necessary for conclusive proof of the capture of radioactive particles from the stratosphere by precipitating clouds. However, for large-scale global studies of fallout transport, errors of 50 to 100 miles in the location of air parcels with certain potential. During the 1963 study, it was found that the flow patterns at different levels were seriously affected by coding and plotting errors in the radiosonde data which often escape attention in conventional upper air analyses

  6. Logistics case study based research: Towards higher quality

    DEFF Research Database (Denmark)

    Pedrosa, Alex; Näslund, Dag; Jasmand, Claudia

    2012-01-01

    analysis of 134 case study based articles published in six leading logistics and supply chain management (SCM) journals between 1998 and 2010 is used to assess and evaluate the quality of the case study based research approach as documented in these publications. Findings – This research provides...... to address to ensure high quality of the case study based research approach in published articles. Research limitations/implications – This study is limited to the analysis of published articles in six logistics and SCM journals. Further research should investigate different journals in logistics and other...

  7. PET IMAGING STUDIES IN DRUG ABUSE RESEARCH.

    Energy Technology Data Exchange (ETDEWEB)

    Fowler, J.S.; Volkow, N.D.; Ding, Y.S.; Logan, J.; Wang, G.J.

    2001-01-29

    . This will be followed by highlights of PET studies of the acute effects of the psychostimulant drugs cocaine and methylphenidate (ritalin) and studies of the chronic effects of cocaine and of tobacco smoke on the human brain. This chapter concludes with the description of a study which uses brain imaging coupled with a specific pharmacological challenge to address the age-old question of why some people who experiment with drugs become addicted while others do not.

  8. Accelerator research studies: Progress report, Task C

    International Nuclear Information System (INIS)

    1985-06-01

    The major effort reported is the study of the feasibility of a 300 MW gyroklystron at ∼9 GHz, and substantial progress has been made. A four-cavity gyroklystron design has been shown to be capable of linear gain as high as 66 dB and to be marginally stable against oscillation in any mode. AM and PM sensitivities to fluctuation in system parameters have also been calculated in the regime of linear operation. Initial non-linear design calculations have also been carried out which include the effect of tapering the axial magnetic guide field over the length of a gyroklystron circuit. Although these calculations are preliminary they do indicate potential for significant efficiency enhancement by magnetic field shaping techniques

  9. Amlodipine+benazepril is superior to hydrochlorothiazide+benazepril irrespective of baseline pulse pressure: subanalysis of the ACCOMPLISH trial.

    Science.gov (United States)

    Skoglund, Per H; Svensson, Per; Asp, Joline; Dahlöf, Björn; Kjeldsen, Sverre E; Jamerson, Kenneth A; Weber, Michael A; Jia, Yan; Zappe, Dion H; Östergren, Jan

    2015-02-01

    Pulse pressure (PP) is an independent risk factor for cardiovascular (CV) disease and death but few studies have investigated the effect of antihypertensive treatments in relation to PP levels before treatment. The Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With Systolic Hypertension (ACCOMPLISH) trial showed that the combination of benazepril+amlodipine (B+A) is superior to benazepril+hydrochlorothiazide (B+H) in reducing CV events. We aimed to investigate whether the treatment effects in the ACCOMPLISH trial were dependent on baseline PP. High-risk hypertensive patients (n=11,499) were randomized to double-blinded treatment with single-pill combinations of either B+A or B+H and followed for 36 months. Patients were divided into tertiles according to their baseline PP and events (CV mortality/myocardial infarction or stroke) were compared. Hazard ratios (HRs) for the treatment effect (B+A over B+H) were calculated in a Cox regression model with age, coronary artery disease, and diabetes mellitus as covariates and were compared across the tertiles. The event rate was increased in the high tertile of PP compared with the low tertile (7.2% vs 4.4% P<.01). In the high and medium PP tertiles, HRs were 0.75 (95% confidence interval [CI], 0.60-0.95; P=.018) and 0.74 (CI, 0.56-0.98, P=.034), respectively, in favor of B+A. There was no significant difference between the treatments in the low tertile and no significant differences in treatment effect when comparing the HRs between tertiles of PP. B+A has superior CV protection over B+H in high-risk hypertensive patients independent of baseline PP although the absolute treatment effect is enhanced in the higher tertiles of PP where event rates are higher. © 2014 Wiley Periodicals, Inc.

  10. Whole-brain grey matter density predicts balance stability irrespective of age and protects older adults from falling.

    Science.gov (United States)

    Boisgontier, Matthieu P; Cheval, Boris; van Ruitenbeek, Peter; Levin, Oron; Renaud, Olivier; Chanal, Julien; Swinnen, Stephan P

    2016-03-01

    Functional and structural imaging studies have demonstrated the involvement of the brain in balance control. Nevertheless, how decisive grey matter density and white matter microstructural organisation are in predicting balance stability, and especially when linked to the effects of ageing, remains unclear. Standing balance was tested on a platform moving at different frequencies and amplitudes in 30 young and 30 older adults, with eyes open and with eyes closed. Centre of pressure variance was used as an indicator of balance instability. The mean density of grey matter and mean white matter microstructural organisation were measured using voxel-based morphometry and diffusion tensor imaging, respectively. Mixed-effects models were built to analyse the extent to which age, grey matter density, and white matter microstructural organisation predicted balance instability. Results showed that both grey matter density and age independently predicted balance instability. These predictions were reinforced when the level of difficulty of the conditions increased. Furthermore, grey matter predicted balance instability beyond age and at least as consistently as age across conditions. In other words, for balance stability, the level of whole-brain grey matter density is at least as decisive as being young or old. Finally, brain grey matter appeared to be protective against falls in older adults as age increased the probability of losing balance in older adults with low, but not moderate or high grey matter density. No such results were observed for white matter microstructural organisation, thereby reinforcing the specificity of our grey matter findings. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. Research-practice interactions as reported in recent design research studies: Still promising, still hazy

    NARCIS (Netherlands)

    Ormel, Bart; Pareja Roblin, Natalie; McKenney, Susan; Voogt, Joke; Pieters, Jules

    2012-01-01

    Ormel, B., Pareja Roblin, N., McKenney, S., Voogt, J., & Pieters, J. (2012). Research-practice interactions as reported in recent design research studies: Still promising, still hazy. Educational Technology Research & Development, 60(6), 967-986. doi:10.1007/s11423-012-9261-6

  12. Research Costs Investigated: A Study Into the Budgets of Dutch Publicly Funded Drug-Related Research

    NARCIS (Netherlands)

    T. van Asselt (Thea); B.L.T. Ramaekers (Bram); I. Corro Ramos (Isaac); M.A. Joore (Manuela); M.J. Al (Maiwenn); Lesman-Leegte, I. (Ivonne); M.J. Postma (Maarten); P. Vemer (Pepijn); T.L. Feenstra (Talitha)

    2017-01-01

    textabstractBackground: The costs of performing research are an important input in value of information (VOI) analyses but are difficult to assess. Objective: The aim of this study was to investigate the costs of research, serving two purposes: (1) estimating research costs for use in VOI analyses;

  13. Research Costs Investigated : A Study Into the Budgets of Dutch Publicly Funded Drug-Related Research

    NARCIS (Netherlands)

    van Asselt, Thea; Ramaekers, Bram; Corro Ramos, Isaac; Joore, Manuela; Al, Maiwenn; Lesman-Leegte, Ivonne; Postma, Maarten; Vemer, Pepijn; Feenstra, Talitha

    BACKGROUND: The costs of performing research are an important input in value of information (VOI) analyses but are difficult to assess. OBJECTIVE: The aim of this study was to investigate the costs of research, serving two purposes: (1) estimating research costs for use in VOI analyses; and (2)

  14. Getting started in research: designing and preparing to conduct a research study.

    Science.gov (United States)

    Macfarlane, Matthew D; Kisely, Steve; Loi, Samantha; Macfarlane, Stephen; Merry, Sally; Parker, Stephen; Power, Brian; Siskind, Dan; Smith, Geoff; Looi, Jeffrey C

    2015-02-01

    To discuss common pitfalls and useful tips in designing a quantitative research study, the importance and process of ethical approval, and consideration of funding. Through careful planning, based on formulation of a research question, early career researchers can design and conduct quantitative research projects within the framework of the Scholarly Project or in their own independent projects. © The Royal Australian and New Zealand College of Psychiatrists 2014.

  15. A comparative study of behavioural, physical and mental health status between term-limited and tenure-tracking employees in a population of Japanese male researchers.

    Science.gov (United States)

    Nakao, M; Yano, E

    2006-04-01

    Traditional lifelong employment systems have been changing rapidly in Japan. The aim of this study was to assess the health impacts of term-limited employment systems that have recently been introduced into Japanese academic institutes. Cross-sectional. A total of 514 male researchers (275 term limited and 239 tenure track) were compared in terms of behavioural, physical and mental status at annual health examinations. At these examinations, working hours and health-related lifestyles were examined using a self-completed questionnaire. Clinical structured interviews of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) were used to detect major depression. The term-limited researchers tended to work longer hours (Pbreakfast less regularly (P0.05) between the two groups, fatigue was more prevalent (P=0.027) in the term-limited researchers than in the tenure-track researchers, adjusting for the effects of age. Compared with colleagues working in the same laboratories, the term-limited researchers worked longer hours, irrespective of fatigue, whereas only the fatigued tenure-track researchers worked longer hours. In the total sample, the fatigued researchers tended to belong to laboratories where their colleagues, on average, worked longer hours, compared with the non-fatigued researchers. These results imply that the term-limited researchers suffered more from fatigue, due to longer working hours, than their colleagues, and that organized, rather than personal, interventions with respect to the working environment may be effective in reducing overload in such workplaces.

  16. QUALITATIVE STUDIES IN ACCOUNTING: THE ABDUCTIVE. RESEARCH STRATEGY.

    Directory of Open Access Journals (Sweden)

    Claudia URDARI

    2014-11-01

    Full Text Available This paper addresses to accounting researchers and proposes the use of abductive research strategy to improve the quality of accounting research outcomes. We argue that abductive reasoning has developed as a typical research method in all fields of interpretive studies but is still unrecognized by accounting researchers and practitioners. Therefore, this study aims to raise awareness on the benefits obtained through the implementation of abduction as a research strategy. Starting from Peirce (1903 and Blaikie (1993, we explore two types of abduction designs and discuss the advantages of building accounting research on grounded concepts. While this is a conceptual paper that only describes the bridge abduction reasoning can build between studying the reality and new theory emergence, we do not tackle any ethnographical case studies, social survey, or other exploratory field analyses.

  17. Recruiting for research studies using online public advertisements: examples from research in affective disorders.

    Science.gov (United States)

    Wise, Toby; Arnone, Danilo; Marwood, Lindsey; Zahn, Roland; Lythe, Karen E; Young, Allan H

    2016-01-01

    Successful recruitment is vital for any research study. Difficulties in recruitment are not uncommon and can have important implications. This is particularly relevant to research conducted in affective disorders due to the nature of the conditions and the clinical services that serve these patients. Recently, online public advertisements have become more generally accessible and may provide an effective way to recruit patient populations. However, there is paucity of evidence on their viability as a method of recruiting patients into studies of disease mechanisms in these disorders. Public advertisement methods can be useful when researchers require specific populations, such as those not receiving pharmacological treatment. This work describes our experience in successfully recruiting participants into neuroimaging research studies in affective disorders using online public advertisements. Results suggest that these online public advertisements are an effective method for successfully recruiting participants with affective disorders into research studies, particularly for research focusing on disease mechanisms in specific populations.

  18. Review of research grant allocation to psychosocial studies in diabetes research

    DEFF Research Database (Denmark)

    Jones, A; Vallis, Michael; Cooke, Debbie

    2016-01-01

    AIMS: To estimate and discuss the allocation of diabetes research funds to studies with a psychosocial focus. METHODS: Annual reports and funded-research databases from approximately the last 5 years (if available) were reviewed from the following representative funding organizations, the American...... Diabetes Association, the Canadian Diabetes Association, Diabetes Australia, Diabetes UK, the Dutch Diabetes Research Foundation and the European Foundation for the Study of Diabetes, in order to estimate the overall proportion of studies allocated research funding that had a psychosocial focus. RESULTS......: An estimated mean of 8% of funded studies from our sample were found to have a psychosocial focus. CONCLUSIONS: The proportion of funded studies with a psychosocial focus was small, with an estimated mean ratio of 17:1 observed between funded biomedical and psychosocial studies in diabetes research. While...

  19. Researching Language Teacher Cognition and Practice: International Case Studies

    Science.gov (United States)

    Barnard, Roger, Ed.; Burns, Anne, Ed.

    2012-01-01

    This book presents a novel approach to discussing how to research language teacher cognition and practice. An introductory chapter by the editors and an overview of the research field by Simon Borg precede eight case studies written by new researchers, each of which focuses on one approach to collecting data. These approaches range from…

  20. Teacher research as self-study and collaborative activity

    OpenAIRE

    Gade, Sharada

    2015-01-01

    This article highlights two insightful methods for advancing teacher research: practitioner self-study in relation to a range of texts, with which to examine one’s educational landscape; and classroom interventions conceived as a Vygotskian activity, via teacher-researcher collaboration. Both approaches allow teachers and collaborating researchers to share individual expertise across institutional boundaries and engage in creative local action.

  1. Research Governance and the Role of Evaluation: A Comparative Study

    Science.gov (United States)

    Molas-Gallart, Jordi

    2012-01-01

    Through a comparative study of the United Kingdom and Spain, this article addresses the effect of different research governance structures on the functioning and uses of research evaluation. It distinguishes three main evaluation uses: distributive, improvement, and controlling. Research evaluation in the United Kingdom plays important…

  2. Research Review of the Institute of African Studies

    African Journals Online (AJOL)

    Please note: As of 2013 the Research Review of the Institute of African Studies is now publishing under the title Contemporary Journal of African Studies. You can view the CJAS pages on AJOL here: http://www.ajol.info/index.php/contjas/index. The Research Review of the Institute of African Studies at the University of ...

  3. Teachers' Views about Educational Research: A Qualitative Study

    Science.gov (United States)

    Bas, Gökhan; Kivilcim, Zafer Savas

    2017-01-01

    The purpose of this case study is to examine the views of teachers' about educational research. The present research is designed as a qualitative case study. The group of this study is consisted of teachers (n = 27), working in primary, middle, and high schools in the province of Nigde in Turkey. An extensive literature review was made on…

  4. Assessment of children's capacity to consent for research: a descriptive qualitative study of researchers' practices.

    Science.gov (United States)

    Gibson, Barbara E; Stasiulis, Elaine; Gutfreund, Shawna; McDonald, Maria; Dade, Lauren

    2011-08-01

    In Canadian jurisdictions without specific legislation pertaining to research consent, the onus is placed on researchers to determine whether a child is capable of independently consenting to participate in a research study. Little, however, is known about how child health researchers are approaching consent and capacity assessment in practice. The aim of this study was to explore and describe researchers' current practices. The study used a qualitative descriptive design consisting of 14 face-to-face interviews with child health researchers and research assistants in Southern Ontario. Transcribed interviews were analysed for common themes. Procedures for assessing capacity varied considerably from the use of age cutoffs to in-depth engagement with each child. Three key issues emerged from the accounts: (1) requirements that consent be provided by a single person thwarted researchers' abilities to support family decision-making; (2) little practical distinction was made between assessing if a child was capable, versus determining if study information had been adequately explained by the researcher; and (3) participants' perceived that review boards' requirements may conflict with what they considered ethical consent practices. The results suggest that researchers' consent and capacity knowledge and skills vary considerably. Perceived discrepancies between ethical practice and ethics boards' requirements suggest the need for dialogue, education and possibly ethics board reforms. Furthermore we propose, where appropriate, a 'family decision-making' model that allows parents and their children to consent together, thereby shifting the focus from separate assent and consent procedures to approaches that appropriately engage the child and family.

  5. Mixed methods research design for pragmatic psychoanalytic studies.

    Science.gov (United States)

    Tillman, Jane G; Clemence, A Jill; Stevens, Jennifer L

    2011-10-01

    Calls for more rigorous psychoanalytic studies have increased over the past decade. The field has been divided by those who assert that psychoanalysis is properly a hermeneutic endeavor and those who see it as a science. A comparable debate is found in research methodology, where qualitative and quantitative methods have often been seen as occupying orthogonal positions. Recently, Mixed Methods Research (MMR) has emerged as a viable "third community" of research, pursuing a pragmatic approach to research endeavors through integrating qualitative and quantitative procedures in a single study design. Mixed Methods Research designs and the terminology associated with this emerging approach are explained, after which the methodology is explored as a potential integrative approach to a psychoanalytic human science. Both qualitative and quantitative research methods are reviewed, as well as how they may be used in Mixed Methods Research to study complex human phenomena.

  6. Confidentiality in participatory research: Challenges from one study.

    Science.gov (United States)

    Petrova, Elmira; Dewing, Jan; Camilleri, Michelle

    2016-06-01

    This article presents key ethical challenges that were encountered when conducting a participatory qualitative research project with a very specific, small group of nurses, in this case with practice development nurses in Malta. With the small number of nurses employed in practice development roles in Malta, there are numerous difficulties of maintaining confidentiality. Poorly constructed interventions by the researcher could have resulted in detrimental effects to research participants and the overall trustworthiness of the research. Generally, ethical guidelines for research exist to reinforce validity of research; however, there is not an established consensus on how these strategies can be utilised in some types of qualitative field work. The researcher used an exploratory case study methodology. The sample consisted of 10 participants who were interviewed twice using face-to-face interviews, over a period of 2 months. The study was ethically reviewed by the University Research Ethics Committee and the Faculty Research Ethics Committee, University of Malta. The participants referred to in this article have been given adequate information about the study and their consent has been obtained. Numerous strategies for ensuring confidentiality during recruitment of the participants, during data collection, during transcription and data analysis and during dissemination of research results assisted the researcher in responding to potential and actual ethical issues. This article emphasises the main strategies that can be used to respond to ethical challenges when researching with a small easily identifiable group. The learning discussed here may be relevant to or even transferable to other similar research studies or research contexts. These methods fostered a greater credibility throughout the research process and predisposed the participants to greater trust, and thus, they disclosed their experiences and speak more freely, thus enhancing the quality of the study

  7. Priorities in public relations research: An international Delphi study

    OpenAIRE

    Watson, Tom

    2008-01-01

    A Delphi study on the priorities for public relations research, conducted in 2007 amongst\\ud academics, practitioners and senior executives of professional and industry bodies in five\\ud continents, has ranked the ten most important topics for research and proposed the associated\\ud research questions. This is the first completed Delphi study into public relations research since\\ud Synnott and McKie (1997) which was itself a development of earlier studies of this type by\\ud McElreath (1980, 1...

  8. Disclosure of genetics research results after the death of the patient participant: a qualitative study of the impact on relatives.

    Science.gov (United States)

    Ormondroyd, E; Moynihan, C; Watson, M; Foster, C; Davolls, S; Ardern-Jones, A; Eeles, R

    2007-08-01

    When a gene mutation is identified in a research study following the death of the study participant, it is not clear whether such information should be made available to relatives. We report here an evaluation of the impact on relatives of being informed of study results that detected pathogenic BRCA2 mutations in a male relative, now deceased, who had early onset (under the age of 55) prostate cancer. The breast and ovarian cancer risk was unknown to the living relatives. Qualitative analysis of interviews with thirteen relatives indicated that those who had a higher risk perception, resulting from an awareness of cancer family history or experiential knowledge of cancer in their family, tended to adjust more easily to the results. All participants believed that genetics research results of clinical significance should be fed back to relatives. Those who were fully aware of the BRCA2 results and implications for themselves felt they had benefited from the information, irrespective of whether or not they had elected for genetic testing, because of the consequent availability of surveillance programs. Initial anxiety upon learning about the BRCA2 result was alleviated by genetic counselling. Factors influencing those who have not engaged with the information included scepticism related to the relative who attempted to inform them, young age and fear of cancer. Those who had not sought genetic counselling did not attempt further dissemination, and some were not undergoing regular screening. Implications for informed consent in genetics research programs, and the requirement for genetic counselling when research results are disclosed, are discussed.

  9. Perceptions of physiotherapists towards research: a mixed methods study.

    Science.gov (United States)

    Janssen, J; Hale, L; Mirfin-Veitch, B; Harland, T

    2016-06-01

    To explore the perceptions of physiotherapists towards the use of and participation in research. Concurrent mixed methods research, combining in-depth interviews with three questionnaires (demographics, Edmonton Research Orientation Survey, visual analogue scales for confidence and motivation to participate in research). One physiotherapy department in a rehabilitation hospital, consisting of seven specialised areas. Twenty-five subjects {four men and 21 women, mean age 38 [standard deviation (SD) 11] years} who had been registered as a physiotherapist for a mean period of 15 (SD 10) years participated in this study. They were registered with the New Zealand Board of Physiotherapy, held a current practising certificate, and were working as a physiotherapist or physiotherapy/allied health manager at the hospital. The primary outcome measure was in-depth interviews and the secondary outcome measures were the three questionnaires. Physiotherapists were generally positive towards research, but struggled with the concept of research, the available literature and the time to commit to research. Individual confidence and orientation towards research seemed to influence how these barriers were perceived. This study showed that physiotherapists struggle to implement research in their daily practice and become involved in research. Changing physiotherapists' conceptions of research, making it more accessible and providing dedicated research time could facilitate increased involvement in the physiotherapy profession. Copyright © 2015 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.

  10. Considerations when conducting e-Delphi research: a case study.

    Science.gov (United States)

    Toronto, Coleen

    2017-06-22

    Background E-Delphi is a way to access a geographically dispersed group of experts. It is similar to other Delphi methods but conducted online. E-research methodologies, such as the e-Delphi method, have yet to undergo significant critical discussion. Aim To highlight some of the challenges nurse researchers may wish to consider when using e-Delphi in their research. Discussion This paper provides details about the author's approach to conducting an e-Delphi study in which a group of health literacy nurse experts (n=41) used an online survey platform to identify and prioritise essential health literacy competencies for registered nurses. Conclusion This paper advances methodological discourse about e-Delphi by critically assessing an e-Delphi case study. The online survey platform used in this study was advantageous for the researcher and the experts: the experts could participate at any time and place where the internet was available; the researcher could efficiently access a national group of experts, track responses and analyse data in each round. Implications for practice E-Delphi studies create opportunities for nurse researchers to conduct research nationally and internationally. Before conducting an e-Delphi study, researchers should carefully consider the design and methods for collecting data, to avoid challenges that could potentially compromise the quality of the findings. Researchers are encouraged to publish details about their approaches to e-Delphi studies, to advance the state of the science.

  11. Middle School Responses to Cyberbullying: An Action Research Study

    Science.gov (United States)

    Zidack, Astri Marie

    2013-01-01

    This action research study engaged a small public middle school in the northwest United States in a collaborative process to address cyberbullying issues that often lead to academic and behavior problems in schools (Hinduja, 2010; Olweus, 2010). The specific purpose of this action research study was to address the middle school's cyberbullying…

  12. Updating the School Counseling Research Agenda: A Delphi Study

    Science.gov (United States)

    Villares, Elizabeth; Dimmitt, Carey

    2017-01-01

    The authors updated an earlier Delphi study identifying the research priorities for school counseling (Dimmitt et al., 2005). A 29-member expert panel selected research questions from the prior study, generated new questions, and rank ordered the combined set. The results provide guidance for prioritizing dissertation topics, targeting future…

  13. Collagen gel contraction serves to rapidly distinguish epithelial- and mesenchymal-derived cells irrespective of alpha-smooth muscle actin expression

    DEFF Research Database (Denmark)

    Nielsen, Helga Lind; Gudjonsson, Thorarinn; Villadsen, René

    2004-01-01

    Mesenchymal-like cells in the stroma of breast cancer may arise as a consequence of plasticity within the epithelial compartment, also referred to as epithelial-mesenchymal transition, or by recruitment of genuine mesenchymal cells from the peritumoral stroma. Cells of both the epithelial...... compartment and the stromal compartment express alpha smooth muscle actin (alpha-sm actin) as part of a myoepithelial or a myofibroblastic differentiation program, respectively. Moreover, because both epithelial- and mesenchymal-derived cells are nontumorigenic, other means of discrimination are warranted....... Here, we describe the contraction of hydrated collagen gels as a rapid functional assay for the distinction between epithelial- and mesenchymal-derived stromal-like cells irrespective of the status of alpha-sm actin expression. Three epithelial-derived cell lines and three genuine mesenchymal...

  14. Research designs and making causal inferences from health care studies.

    Science.gov (United States)

    Flannelly, Kevin J; Jankowski, Katherine R B

    2014-01-01

    This article summarizes the major types of research designs used in healthcare research, including experimental, quasi-experimental, and observational studies. Observational studies are divided into survey studies (descriptive and correlational studies), case-studies and analytic studies, the last of which are commonly used in epidemiology: case-control, retrospective cohort, and prospective cohort studies. Similarities and differences among the research designs are described and the relative strength of evidence they provide is discussed. Emphasis is placed on five criteria for drawing causal inferences that are derived from the writings of the philosopher John Stuart Mill, especially his methods or canons. The application of the criteria to experimentation is explained. Particular attention is given to the degree to which different designs meet the five criteria for making causal inferences. Examples of specific studies that have used various designs in chaplaincy research are provided.

  15. A facility for using cluster research to study environmental problems

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-01

    This report begins by describing the general application of cluster based research to environmental chemistry and the development of a Cluster Structure and Dynamics Research Facility (CSDRF). Next, four important areas of cluster research are described in more detail, including how they can impact environmental problems. These are: surface-supported clusters, water and contaminant interactions, time-resolved dynamic studies in clusters, and cluster structures and reactions. These facilities and equipment required for each area of research are then presented. The appendices contain workshop agenda and a listing of the researchers who participated in the workshop discussions that led to this report.

  16. A facility for using cluster research to study environmental problems

    International Nuclear Information System (INIS)

    1991-11-01

    This report begins by describing the general application of cluster based research to environmental chemistry and the development of a Cluster Structure and Dynamics Research Facility (CSDRF). Next, four important areas of cluster research are described in more detail, including how they can impact environmental problems. These are: surface-supported clusters, water and contaminant interactions, time-resolved dynamic studies in clusters, and cluster structures and reactions. These facilities and equipment required for each area of research are then presented. The appendices contain workshop agenda and a listing of the researchers who participated in the workshop discussions that led to this report

  17. Research

    African Journals Online (AJOL)

    abp

    2016-07-12

    Jul 12, 2016 ... multiple risk factors provides support for multiple-behavior interventions as ... consumption) with smoking therefore needs further research. As such this study .... restaurants, in bars, and on a statewide basis. They preferred to.

  18. Research

    African Journals Online (AJOL)

    The mini-clinical-evaluation exercise (mini-CEX) is a way of assessing the clinical ... Ethical approval for this study was obtained from the Medical Health. Research ..... mini-CEX assessment and feedback session, the greater the likelihood of.

  19. Research

    African Journals Online (AJOL)

    abp

    2016-04-14

    Apr 14, 2016 ... Qualitative data, content analysis approach was used. Results: Overall 422 .... Study design: A mixed method cross-sectional design using both quantitative and qualitative research methods as described by. Hanson et al [33] ...

  20. Research

    African Journals Online (AJOL)

    Research. December 2017, Vol. 9, No. 4 AJHPE 171. During curriculum development, teachers ... Ideally, examiners need an educational method to determine ..... A major focus of this study was addressing the human resource gap when.

  1. Design study of underground facility of the Underground Research Laboratory

    International Nuclear Information System (INIS)

    Hibiya, Keisuke; Akiyoshi, Kenji; Ishizuka, Mineo; Anezaki, Susumu

    1998-03-01

    Geoscientific research program to study deep geological environment has been performed by Power Reactor and Nuclear Fuel Development Corporation (PNC). This research is supported by 'Long-Term Program for Research, Development and Utilization of Nuclear Energy'. An Underground Research Laboratory is planned to be constructed at Shoma-sama Hora in the research area belonging to PNC. A wide range of geoscientific research and development activities which have been previously studied at the Tono Area is planned in the laboratory. The Underground Research Laboratory is consisted of Surface Laboratory and Underground Research Facility located from the surface down to depth between several hundreds and 1,000 meters. Based on the results of design study in last year, the design study performed in this year is to investigate the followings in advance of studies for basic design and practical design: concept, design procedure, design flow and total layout. As a study for the concept of the underground facility, items required for the facility are investigated and factors to design the primary form of the underground facility are extracted. Continuously, design methods for the vault and the underground facility are summarized. Furthermore, design procedures of the extracted factors are summarized and total layout is studied considering the results to be obtained from the laboratory. (author)

  2. Qualitative case study methodology in nursing research: an integrative review.

    Science.gov (United States)

    Anthony, Susan; Jack, Susan

    2009-06-01

    This paper is a report of an integrative review conducted to critically analyse the contemporary use of qualitative case study methodology in nursing research. Increasing complexity in health care and increasing use of case study in nursing research support the need for current examination of this methodology. In 2007, a search for case study research (published 2005-2007) indexed in the CINAHL, MEDLINE, EMBASE, PsychINFO, Sociological Abstracts and SCOPUS databases was conducted. A sample of 42 case study research papers met the inclusion criteria. Whittemore and Knafl's integrative review method guided the analysis. Confusion exists about the name, nature and use of case study. This methodology, including terminology and concepts, is often invisible in qualitative study titles and abstracts. Case study is an exclusive methodology and an adjunct to exploring particular aspects of phenomena under investigation in larger or mixed-methods studies. A high quality of case study exists in nursing research. Judicious selection and diligent application of literature review methods promote the development of nursing science. Case study is becoming entrenched in the nursing research lexicon as a well-accepted methodology for studying phenomena in health and social care, and its growing use warrants continued appraisal to promote nursing knowledge development. Attention to all case study elements, process and publication is important in promoting authenticity, methodological quality and visibility.

  3. Assessing the benefits of OHER (Office of Health and Environmental Research) research: Three case studies

    Energy Technology Data Exchange (ETDEWEB)

    Nesse, R.J.; Callaway, J.M.; Englin, J.E.; Klan, M.S.; Nicholls, A.K.; Serot, D.E.

    1987-09-01

    This research was undertaken to estimate the societal benefits and costs of selected past research performed for the Office of Health and Environmental Research (OHER) of the US Department of Energy (DOE). Three case studies of representative OHER and DOE research were performed. One of these, the acid rain case study, includes research conducted elsewhere in DOE. The other two cases were the OHER marine research program and the development of high-purity germanium that is used in radiation detectors. The acid rain case study looked at the research benefits and costs of furnace sorbent injection and duct injection, technologies that might reduce acid deposition precursors. Both appear to show benefits in excess of costs. We examined in detail one of the OHER marine research program's accomplishments - the increase in environmental information used by the Outer Continental Shelf leasing program to manage bidding for off-shore oil drilling. The results of an econometric model show that environmental information of the type supported by OHER is unequivocally linked to government and industry leasing decisions. The germanium case study indicated that the benefits of germanium radiation detectors were significant.

  4. Profiling academic research on discourse studies and second language learning

    Directory of Open Access Journals (Sweden)

    Harold Castañeda

    2012-06-01

    Full Text Available There is little profiling academic research on discourse studies in relation to second language learning from a regional perspective. Thisstudy aims at unveiling what, when, where and who constitute scholarly work in research about these two interrelated fields. A dataset wasconfigured from registers taken from Dialnet and studied using specialized text-mining software. Findings revealed myriad research interests,few prolific years and the lack of networking. It is recommended to trace out our research as an ELT community locally and globally.

  5. Regional and detailed research studies for stone resources in Korea

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-01

    This report consists of 7 articles. 1) Detail drilling research works on granodiorite stock of Cheanan area near Onyang city in Chungnam province. 2) Regional research studies on granites distributed in Kimje - Jeongeup. 3) Regional survey and feasibility study on diorite rock mass in Kohyeng, Cheonnam province. 4) Regional research study on the stone resources of Hamyang area. 5) A study on variation trends of physical properties of 5 kinds of building stone by means of Weather-Ometer experiment. 6) Borehole radar survey at the granodiorite quarry mine, Cheonan, Chungnam province. 7) Radar velocity tomography in anisotropic media. (author). refs., tabs., figs.

  6. Benchmarking study of corporate research management and planning practices

    Science.gov (United States)

    McIrvine, Edward C.

    1992-05-01

    During 1983-84, Xerox Corporation was undergoing a change in corporate style through a process of training and altered behavior known as Leadership Through Quality. One tenet of Leadership Through Quality was benchmarking, a procedure whereby all units of the corporation were asked to compare their operation with the outside world. As a part of the first wave of benchmark studies, Xerox Corporate Research Group studied the processes of research management, technology transfer, and research planning in twelve American and Japanese companies. The approach taken was to separate `research yield' and `research productivity' (as defined by Richard Foster) and to seek information about how these companies sought to achieve high- quality results in these two parameters. The most significant findings include the influence of company culture, two different possible research missions (an innovation resource and an information resource), and the importance of systematic personal interaction between sources and targets of technology transfer.

  7. Critical methodologies: early childhood research studies in Norway

    OpenAIRE

    Rhedding-Jones, Jeanette; Bjelkerud, Agnes Westgaard; Giæver, Katrine; Røkholt, Eline Grelland; Holten, Ingeborg Caroline Sæbøe; Lafton, Tove; Moxnes, Anna Rigmor; Pope, Liv Alice

    2014-01-01

    This is an open access article licensed under a Creative Commons Attribution 4.0 International License and originally published in Reconceptualizing Educational Research Methodology (RERM). You can access the article on publisher's website by following this link: https://journals.hioa.no/index.php/rerm This chapter exemplifies seven projects and their related research methodologies. It does so to consider how to construct critical research studies without replicating someone else’s researc...

  8. THE BASIC PRINCIPLES OF RESEARCH IN NEUROEDUCATION STUDIES

    OpenAIRE

    Ali Nouri

    2016-01-01

    The present paper assembles contributions from the areas of education, psychology, cognitive science, and of course, neuroeducation itself to introduce the basic principles of research in the field of neuroeducation studies. It is particularly important, as such it is a useful way to justify researchers about what neuroeducation as a specific domain do that no other field can do as well or cannot do at all. Based on the literature reviewed, neuroeducational research can be understood as an inte...

  9. Marketing Plan and Marketing Research for KUAS Game Studies

    OpenAIRE

    Tukiainen, Reno

    2012-01-01

    This thesis was commissioned by Tieto^2 Project. The aim of the thesis was to study higher education marketing, including marketing planning and marketing research, from the point of view of marketing Kajaani University of Applied Sciences game study programmes. After the relevant theoretical literature was reviewed, a marketing research was conducted by interviewing current KUAS game students and new applicants who had applied for KUAS game studies in the spring of 2012. Based on the analyse...

  10. Research priorities in medical education: A national study

    Directory of Open Access Journals (Sweden)

    Mina Tootoonchi

    2012-01-01

    Full Text Available Background: One preliminary step to strengthen medical education research would be determining the research prior-ities. The aim of this study was to determine the research priorities of medical education in Iran in 2007-2008. Methods: This descriptive study was carried out in two phases. Phase one was performed in 3 stages and used Delphi technique among academic staffs of Isfahan University of Medical Sciences. The three stages included a brainstorming workshop for 140 faculty members and educational experts resulting in a list of research priorities, then, in the second and third stages 99 and 76 questionnaires were distributed among faculty members. In the second phase, the final ques-tionnaires were mailed to educational research center managers of universities type I, II and III, and were distributed among 311 academic members and educational experts to rate the items on a numerical scale ranging from 1 to 10. Results: The most important research priorities included faculty members′ development methods, faculty members′ motives, satisfaction and welfare, criteria and procedures of faculty members′ promotion, teaching methods and learning techniques, job descriptions and professional skills of graduates, quality management in education, second language, clinical education, science production in medicine, faculty evaluation and information technology. Conclusions: This study shows the medial education research priorities in national level and in different types of medical universities in Iran. It is recommended that faculty members and research administrators consider the needs and requirements of education and plan the researches in education according to these priorities.

  11. Research priorities in medical education: A national study.

    Science.gov (United States)

    Tootoonchi, Mina; Yamani, Nikoo; Changiz, Tahereh; Yousefy, Alireza

    2012-01-01

    One preliminary step to strengthen medical education research would be determining the research priorities. The aim of this study was to determine the research priorities of medical education in Iran in 2007-2008. This descriptive study was carried out in two phases. Phase one was performed in 3 stages and used Delphi technique among academic staffs of Isfahan University of Medical Sciences. The three stages included a brainstorming workshop for 140 faculty members and educational experts resulting in a list of research priorities, then, in the second and third stages 99 and 76 questionnaires were distributed among faculty members. In the second phase, the final questionnaires were mailed to educational research center managers of universities type I, II and III, and were distributed among 311 academic members and educational experts to rate the items on a numerical scale ranging from 1 to 10. The most important research priorities included faculty members' development methods, faculty members' motives, satisfaction and welfare, criteria and procedures of faculty members' promotion, teaching methods and learning techniques, job descriptions and professional skills of graduates, quality management in education, second language, clinical education, science production in medicine, faculty evaluation and information technology. This study shows the medial education research priorities in national level and in different types of medical universities in Iran. It is recommended that faculty members and research administrators consider the needs and requirements of education and plan the researches in education according to these priorities.

  12. Recruiting for research studies using online public advertisements examples from research in affective disorders

    Directory of Open Access Journals (Sweden)

    Wise T

    2016-02-01

    Full Text Available Toby Wise,1 Danilo Arnone,1 Lindsey Marwood,1 Roland Zahn,1–3 Karen E Lythe,2,3 Allan H Young1 1Centre for Affective Disorders, Department of Psychological Medicine, Institute of Psychiatry, King’s College London, London, 2Neuroscience and Aphasia Research Unit, School of Psychological Sciences, 3Manchester Academic Health Science Centre, University of Manchester, Manchester, UK Abstract: Successful recruitment is vital for any research study. Difficulties in recruitment are not uncommon and can have important implications. This is particularly relevant to research conducted in affective disorders due to the nature of the conditions and the clinical services that serve these patients. Recently, online public advertisements have become more generally accessible and may provide an effective way to recruit patient populations. However, there is paucity of evidence on their viability as a method of recruiting patients into studies of disease mechanisms in these disorders. Public advertisement methods can be useful when researchers require specific populations, such as those not receiving pharmacological treatment. This work describes our experience in successfully recruiting participants into neuroimaging research studies in affective disorders using online public advertisements. Results suggest that these online public advertisements are an effective method for successfully recruiting participants with affective disorders into research studies, particularly for research focusing on disease mechanisms in specific populations. Keywords: recruitment, affective disorders, advertising, depression, anxiety, bipolar

  13. Maximising the value of combining qualitative research and randomised controlled trials in health research: the QUAlitative Research in Trials (QUART) study--a mixed methods study.

    Science.gov (United States)

    O'Cathain, Alicia; Thomas, Kate J; Drabble, Sarah J; Rudolph, Anne; Goode, Jackie; Hewison, Jenny

    2014-06-01

    Researchers sometimes undertake qualitative research with randomised controlled trials (RCTs) of health interventions. To systematically explore how qualitative research is being used with trials and identify ways of maximising its value to the trial aim of providing evidence of effectiveness of health interventions. A sequential mixed methods study with four components. (1) Database search of peer-reviewed journals between January 2008 and September 2010 for articles reporting the qualitative research undertaken with specific trials, (2) systematic search of database of registered trials to identify studies combining qualitative research and trials, (3) survey of 200 lead investigators of trials with no apparent qualitative research and (4) semistructured telephone interviews with 18 researchers purposively sampled from the first three methods. Qualitative research was undertaken with at least 12% of trials. A large number of articles reporting qualitative research undertaken with trials (n=296) were published between 2008 and 2010. A total of 28% (82/296) of articles reported qualitative research undertaken at the pre-trial stage and around one-quarter concerned drugs or devices. The articles focused on 22 aspects of the trial within five broad categories. Some focused on more than one aspect of the trial, totalling 356 examples. The qualitative research focused on the intervention being trialled (71%, 254/356), the design and conduct of the trial (15%, 54/356), the outcomes of the trial (1%, 5/356), the measures used in the trial (3%, 10/356), and the health condition in the trial (9%, 33/356). The potential value of the qualitative research to the trial endeavour included improving the external validity of trials and facilitating interpretation of trial findings. This value could be maximised by using qualitative research more at the pre-trial stage and reporting findings with explicit attention to the implications for the trial endeavour. During interviews

  14. Hurricane Sandy: An Educational Bibliography of Key Research Studies

    Science.gov (United States)

    Piotrowski, Chris

    2013-01-01

    There, undoubtedly, will be a flurry of research activity in the "Superstorm" Sandy impact area on a myriad of disaster-related topics, across academic disciplines. The purpose of this study was to review the disaster research related specifically to hurricanes in the educational and social sciences that would best serve as a compendium…

  15. Various aspects of lyoluminescence studies in radiation research

    International Nuclear Information System (INIS)

    Kundu, H.K.

    1992-01-01

    Lyoluminescence is the emission of light during the dissolution of irradiated organic and inorganic solids in suitable solvents. This phenomenon has attracted interdisciplinary research involving radiation physics, radiation chemistry and physical chemistry. This paper presents an overall view of the various aspects of lyoluminescence studies in the field of radiation research. (author). 14 refs

  16. Salinity guidelines for irrigation: Case studies from Water Research ...

    African Journals Online (AJOL)

    Salinity guidelines for irrigation: Case studies from Water Research Commission projects along the Lower Vaal, Riet, Berg and Breede Rivers. ... It is suggested that a more dynamic approach be used for managing salinity under irrigation at farm level, i.e. the use of models. Amongst others, future research should focus on ...

  17. Study Offers Keen Insights into Professional Development Research

    Science.gov (United States)

    Killion, Joellen

    2017-01-01

    Joellen Killion is senior advisor to Learning Forward. In each issue of "The Learning Professional", Killion explores a recent research study to help practitioners understand the impact of particular professional learning practices on student outcomes. In this Issue Mary Kennedy conducts a review and analysis of the research on…

  18. CASE STUDY: Cuba — Farmers and Researchers Reshape Cuba's ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2011-01-05

    Jan 5, 2011 ... But working together with groups of farmers, a team of young plant breeders is turning things around. ... English · Français ... CASE STUDY: Cuba — Farmers and Researchers Reshape Cuba's Agriculture ... One method the researchers used to introduce farmers to new or unknown varieties or lines was the ...

  19. Current research projects on traffic conflicts technique studies.

    NARCIS (Netherlands)

    Hondel, M. van den & and Kraay, J.H.

    1979-01-01

    A review of current research concerning the development, evaluation and use of the traffic conflicts technique is presented. The 32 studies, selected from the IRRD data base, are listed alphabetically by names of countries and under countries by names of research organizations. The IRRD descriptions

  20. Exploring research priorities in landscape architecture: An international Delphi study

    NARCIS (Netherlands)

    Meijering, J.V.; Tobi, H.; Brink, van den A.; Morris, F.A.; Bruns, D.

    2015-01-01

    Many of the world's major challenges require responses that are embedded in landscape planning, design, and management. To date, however, it is unclear which research domains should form the core of a future landscape architecture research agenda. This study explored which domains landscape

  1. CASE STUDY: China — Young researchers battle poverty and ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-12-14

    Dec 14, 2010 ... CASE STUDY: China — Young researchers battle poverty and bureaucracy in rural China ... And the “three pig rule” is just one example of the problems the local people ... Revenues were applied to system maintenance and all financial ... The researchers, of course, were trained in science, fieldwork, and ...

  2. Semiconductor Research Corporation: A Case Study in Cooperative Innovation Partnerships

    Science.gov (United States)

    Logar, Nathaniel; Anadon, Laura Diaz; Narayanamurti, Venkatesh

    2014-01-01

    In the study of innovation institutions, it is important to consider how different institutional models can affect a research organization in conducting or funding successful work. As an industry collaborative, Semiconductor Research Corporation (SRC) provides an example of a privately funded institution that leverages the inputs of several member…

  3. Field Research Studying Whales in an Undergraduate Animal Behavior Laboratory

    Science.gov (United States)

    MacLaren, R. David; Schulte, Dianna; Kennedy, Jen

    2012-01-01

    This work describes a new field research laboratory in an undergraduate animal behavior course involving the study of whale behavior, ecology and conservation in partnership with a non-profit research organization--the Blue Ocean Society for Marine Conservation (BOS). The project involves two weeks of training and five weekend trips on whale watch…

  4. Rethinking Research on Teaching: Lessons Learned from an International Study.

    Science.gov (United States)

    Ryan, Doris W.,Ed.; Anderson, Lorin W.,Ed.

    1984-01-01

    Reviewing their "Classroom Environment Study: Teaching for Learning" and other teaching research literature, project personnel examine the limitations of the process-product paradigm typically used in research on teaching. Topics covered include a conceptual model for teaching; preservice and inservice teacher training; appropriate…

  5. Developing Online Communities for Librarian Researchers: A Case Study

    Science.gov (United States)

    Luo, Lili; Kennedy, Marie; Brancolini, Kristine; Stephens, Michael

    2017-01-01

    This study examines the role of online communities in connecting and supporting librarian researchers, through the analysis of member activities in the online community for academic librarians that attended the 2014 Institute for Research Design in Librarianship (IRDL). The 2014 IRDL cohort members participated in the online community via Twitter…

  6. Case Studies Approach in Tourism Destination Branding Research

    Directory of Open Access Journals (Sweden)

    Adeyinka-Ojo S.F.

    2014-01-01

    Full Text Available A review of literature indicates that there are different types of qualitative research methods such as action research, content analysis, ethnography, grounded theory, historical analysis, phenomenology and case study. However, which approach is to be used depends on several factors such as the nature and objectives of the research. The aim of this paper is to focus on the research methodology aspects of applying case study as a research approach and its relevance in tourism destination branding research specifically on a single case study (SCS context. There are arguments that the SCS is a weak research strategy. Some of the potentials or shortcomings highlighted in the literature include the primitive nature of SCS, flexibility of sample technique, data collection method and data analysis. Others include lack of rigour, reliability, validity, credibility of findings and generalisation. This paper has adopted content analysis of the literature on tourism destination branding. Findings indicate that the quality of SCS can be verified using specific case study tactics for four design tests such as validity (construct, internal and external; and reliability using the case study protocol. Theoretical implication suggests that SCS is an empirical enquiry use to understand complex phenomena and favoured by practitioners.

  7. Research Paper An exploratory study of psychological and ...

    African Journals Online (AJOL)

    Research Paper An exploratory study of psychological and developmental issues facing HIV and AIDS affected adolescents living in a residential care facility. Myrthe Van Vilsteren, Sadiyya Haffejee, Rabia Patel, Brett Bowman ...

  8. Public education and enforcement research study : Macomb, Illinois : analysis

    Science.gov (United States)

    2011-03-01

    The Public Education and Enforcement Research Study (PEERS) was a collaborative effort between the Federal Railroad Administration, the Illinois Commerce Commission, and local communities in the State of Illinois. This project was designed to promote...

  9. Northeast Cooperative Research Study Fleet (SF) Program Biological Sampling Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Northeast Cooperative Research Study Fleet (SF) Program partners with a subset of commercial fishermen to collect high quality, high resolution, haul by haul...

  10. USAF Institute for National Security Studies 1998 Research Results Conference

    National Research Council Canada - National Science Library

    1998-01-01

    The USAF Institute for National Security Studies (INSS), in cooperation with HQ USAF Nuclear and Counterproliferation Directorate, sponsored its 6th annual Research Results Conference on 19 - 20 November 1998...

  11. Mutual research capacity strengthening: a qualitative study of two-way partnerships in public health research

    Directory of Open Access Journals (Sweden)

    Redman-MacLaren Michelle

    2012-12-01

    Full Text Available Abstract Introduction Capacity building has been employed in international health and development sectors to describe the process of ‘experts’ from more resourced countries training people in less resourced countries. Hence the concept has an implicit power imbalance based on ‘expert’ knowledge. In 2011, a health research strengthening workshop was undertaken at Atoifi Adventist Hospital, Solomon Islands to further strengthen research skills of the Hospital and College of Nursing staff and East Kwaio community leaders through partnering in practical research projects. The workshop was based on participatory research frameworks underpinned by decolonising methodologies, which sought to challenge historical power imbalances and inequities. Our research question was, “Is research capacity strengthening a two-way process?” Methods In this qualitative study, five Solomon Islanders and five Australians each responded to four open-ended questions about their experience of the research capacity strengthening workshop and activities: five chose face to face interview, five chose to provide written responses. Written responses and interview transcripts were inductively analysed in NVivo 9. Results Six major themes emerged. These were: Respectful relationships; Increased knowledge and experience with research process; Participation at all stages in the research process; Contribution to public health action; Support and sustain research opportunities; and Managing challenges of capacity strengthening. All researchers identified benefits for themselves, their institution and/or community, regardless of their role or country of origin, indicating that the capacity strengthening had been a two-way process. Conclusions The flexible and responsive process we used to strengthen research capacity was identified as mutually beneficial. Using community-based participatory frameworks underpinned by decolonising methodologies is assisting to redress

  12. Guidelines for Qualitative Research in Organization Studies: Controversy and Possibilities

    Directory of Open Access Journals (Sweden)

    Maria Fernanda Rios Cavalcanti

    2017-09-01

    Full Text Available The aim of the present article is to tackle the controversy of establishing guidelines for qualitative research in Organization and Management Theory (OMT and to present a summary of suggestions on how to conduct good qualitative research given by methodologists on top-tier international publications. In order to do so, the article discusses: general guidelines for qualitative research; how to achieve coherence and transparency in a qualitative empirical study; the meaning and importance of the concept of reflexivity; and, finally how to establish a theoretical contribution and transferability of findings in such context. The work presents a valuable contribution because such guidelines, concepts, and approaches can be adopted by students and researchers when conducting a qualitative research proposal, and by periodic reviewers to evaluate the quality of existing empirical studies.

  13. Studies on engineering technologies in the Mizunami Underground Research Laboratory. FY 2007 (Contract research)

    International Nuclear Information System (INIS)

    Noda, Masaru; Suyama, Yasuhiro; Nobuto, Jun; Ijiri, Yuji; Mikake, Shinichiro; Matsui, Hiroya

    2009-07-01

    The Mizunami Underground Research Laboratory (MIU) of the Japan Atomic Energy Agency is a major site for geoscientific research to advance the scientific and technological basis for geological disposal of high-level radioactive waste in crystalline rock. Studies on relevant engineering technologies in the MIU consist of a) research on design and construction technology for very deep underground applications, and b) research on engineering technology as a basis of geological disposal. In the Second Phase of the MIU project (the construction phase), engineering studies have focused on research into design and construction technologies for deep underground. The main subjects in the study of very deep underground structures consist of the following: 'Demonstration of the design methodology', 'Demonstration of existing and supplementary excavation methods', 'Demonstration of countermeasures during excavation' and 'Demonstration of safe construction'. In the FY 2007 studies, identification and evaluation of the subjects for study of engineering technologies in the construction phase were carried out to optimize future research work. Specific studies included: validation of the existing design methodology based on data obtained during construction; validation of existing and supplementary rock excavation methods for very deep shafts; estimation of rock stability under high differential water pressures, methodology on long-term maintenance of underground excavations and risk management systems for construction of underground structures have been performed. Based on these studies, future research focused on the four subject areas, which are 'Demonstration of the design methodology', 'Demonstration of existing and supplementary excavation methods', 'Demonstration of countermeasures during excavation' and 'Demonstration of safe construction', has been identified. The design methodology in the first phase of the MIU Project (surface-based investigation phase) was verified to

  14. Heterogeneity of Human Research Ethics Committees and Research Governance Offices across Australia: An observational study.

    Science.gov (United States)

    De Smit, Elisabeth; Kearns, Lisa S; Clarke, Linda; Dick, Jonathan; Hill, Catherine L; Hewitt, Alex W

    2016-01-01

    Conducting ethically grounded research is a fundamental facet of all investigations. Nevertheless, the administrative burdens of current ethics review are substantial, and calls have been made for a reduction in research waste. To describe the heterogeneity in administration and documentation required by Human Research Ethics Committees (HRECs) and Research Governance Offices (RGOs) across Australia. In establishing a nationwide study to investigate the molecular aetiology of Giant Cell Arteritis (GCA), for which archived pathological specimens from around Australia are being recruited, we identified variation across separate HREC and RGO requirements. Submission paperwork and correspondence from each collaborating site and its representative office for research were reviewed. This data was interrogated to evaluate differences in current guidelines. Twenty-five pathology departments across seven Australian States collaborated in this study. All states, except Victoria, employed a single ethics review model. There was discrepancy amongst HRECs as to which application process applied to our study: seven requested completion of a "National Ethics Application Form" and three a "Low Negligible Risk" form. Noticeable differences in guidelines included whether electronic submission was sufficient. There was variability in the total number of documents submitted (range five to 22) and panel review turnaround time (range nine to 136 days). We demonstrate the challenges and illustrate the heavy workload involved in receiving widespread ethics and governance approval across Australia. We highlight the need to simplify, homogenise, and nationalise human ethics for non-clinical trial studies. Reducing unnecessary administration will enable investigators to achieve research aims more efficiently.

  15. Radiological safety research for nuclear excavation projects - Interoceanic canal studies

    International Nuclear Information System (INIS)

    Klement, A.W. Jr.

    1969-01-01

    The general radiological problems encountered in nuclear cratering and nuclear excavation projects are discussed. Procedures for assessing radiological problems in such projects are outlined. Included in the discussions are source term, meteorology, fallout prediction and ecological factors. Continuing research requirements as well as pre- and post-excavation studies are important considerations. The procedures followed in the current interoceanic canal feasibility studies provide examples of radiological safety problems, current solutions and needed research. (author)

  16. Radiological safety research for nuclear excavation projects - Interoceanic canal studies

    Energy Technology Data Exchange (ETDEWEB)

    Klement, Jr, A W [U.S. Atomic Energy Commission, Las Vegas, NV (United States)

    1969-07-01

    The general radiological problems encountered in nuclear cratering and nuclear excavation projects are discussed. Procedures for assessing radiological problems in such projects are outlined. Included in the discussions are source term, meteorology, fallout prediction and ecological factors. Continuing research requirements as well as pre- and post-excavation studies are important considerations. The procedures followed in the current interoceanic canal feasibility studies provide examples of radiological safety problems, current solutions and needed research. (author)

  17. Considering dance practices as unique cases in interdisciplinary research studies

    DEFF Research Database (Denmark)

    Ravn, Susanne

    ” (Flyvbjerg, 2011) in the domain of qualitative research. Such designs are of specific relevance for research projects exploring body, movement and sensing in general. Thereafter I present the results of some of my resent studies. These studies are based in a critical constructive interdisciplinary......The aim of this paper is to present interdisciplinary considerations of relevance to strengthen dance research in relation to – and in cooperation with - other academic disciplines. I firstly describe how dance practices can be handled as “extreme cases” and cases with “maximal variations...

  18. Preparation of Social Studies Teachers at Major Research Universities.

    Science.gov (United States)

    Dumas, Wayne

    1993-01-01

    Reports on a study of the preparation of secondary social studies teachers at major state-supported research universities. Finds relatively few institutions have followed the Holmes Group recommendations and many continue to prepare broad field social studies teachers leaving them deficient in some social science fields. (CFR)

  19. Case Study Research in Software Engineering Guidelines and Examples

    CERN Document Server

    Runeson, Per; Rainer, Austen; Regnell, Bjorn

    2012-01-01

    Based on their own experiences of in-depth case studies of software projects in international corporations, in this book the authors present detailed practical guidelines on the preparation, conduct, design and reporting of case studies of software engineering.  This is the first software engineering specific book on the case study research method.

  20. Identification of Ambiguity in the Case Study Research Typology

    DEFF Research Database (Denmark)

    Grünbaum, Niels Nolsøe

    2015-01-01

    . Relevant to varied levels and scales of case study use, the aim of this collection is to provide readers with a comprehensive overview of where we are now with case study research, so that they may better judge their own applications of the case study. From definitions to interdisciplinary methods......The purpose of this four volume collection is to provide an accessible selection of the best writing on case study in the English language internationally. Such a collection is timely and highly relevant to students, researchers and academics in higher education, especially when the case......, this set will address the practical case study by offering a structured selection of some of the best modern and classic writing on the case study in article form, together with a synoptic editorial introduction and overview of the field of research....

  1. Decentralized energy studies: Compendium of international studies and research

    Science.gov (United States)

    Wallace, C.

    1980-03-01

    With efficient use of energy, renewable energy sources can supply the majority, if not the totality, of energy supplies in developed nations at real energy prices that double or triple by 2025 (1975 prices). This appears true even in harsh climates with oil dependent industrial economies. Large increases in end-use energy efficiency are cost effective at present prices. Some reports show that cost effective end-use efficiency improvements can reduce energy consumption (per capita, per unit of amenity, or per unit of output) to as much as 90 percent. This was demonstrated by highly disaggregated analyses of end-uses. Such analyses consistently show larger potential for efficiency improvements than can be detected from conventional analyses of more aggregated data. As energy use demands decline due to end use efficiency improvements, energy supply problems subsequently decrease. Lifestyle changes, influenced by social factors, and rising energy prices can substantially reduce demands for energy. Such changes are already discernible in end-use energy studies. When energy efficient capital stock is in place, many end-users of energy will be able to provide a substantial portion of their own energy needs from renewable energy sources that are directly available to them.

  2. Studies and research concerning BNFP. Nuclear spent fuel transportation studies

    International Nuclear Information System (INIS)

    Anderson, R.T.; Maier, J.B.

    1979-11-01

    Currently, there are a number of institutional problems associated with the shipment of spent fuel assemblies from commercial nuclear power plants: new and conflicting regulations, embargoing of certain routes, imposition of transport safeguards, physical security in-transit, and a lack of definition of when and where the fuel will be moved. This report presents a summary of these types and kinds of problems. It represents the results of evaluations performed relative to fuel receipt at the Barnwell Nuclear Fuel Plant. Case studies were made which address existing reactor sites with near-term spent fuel transportation needs. Shipment by either highway, rail, water, or intermodal water-rail was considered. The report identifies the impact of new regulations and uncertainty caused by indeterminate regulatory policy and lack of action on spent fuel acceptance and storage. This stagnant situation has made it impossible for industry to determine realistic transportation scenarios for business planning and financial risk analysis. A current lack of private investment in nuclear transportation equipment is expected to further prolong the problems associated with nuclear spent fuel and waste disposition. These problems are expected to intensify in the 1980's and in certain cases will make continuing reactor plant operation difficult or impossible

  3. Risk for Researchers Studying Social Deviance or Criminal Behavior

    Directory of Open Access Journals (Sweden)

    Patricia L. Brougham

    2017-10-01

    Full Text Available Abstract: Researchers often encounter dangerous situations while conducting social research. The concept of risk to researchers refers to the possible harm that may occur to researchers while in the field or after leaving a research project. This study explores issues experienced by social scientists engaged in research on social deviance or criminal behavior. The goal of this research was to discover the types of risk experienced by social scientists and any mediating factors affecting the experience of risk. An online survey was conducted to gather data on issues experienced by social scientists. This study found that researchers experienced a variety of risks within the categories of physical/health, emotional, legal, and personal/professional. Each of the survey options for risk were reported by at least one respondent; however, the greatest number of risks reported were of an emotional or personal/professional nature. There were no mediating factors found to be significant in relation to the experience of risk. This was a surprising finding especially for the variable of gender as it is suggested that gender plays a role in the experience of difficulties.

  4. THE BASIC PRINCIPLES OF RESEARCH IN NEUROEDUCATION STUDIES

    Directory of Open Access Journals (Sweden)

    Ali Nouri

    2016-06-01

    Full Text Available The present paper assembles contributions from the areas of education, psychology, cognitive science, and of course, neuroeducation itself to introduce the basic principles of research in the field of neuroeducation studies. It is particularly important, as such it is a useful way to justify researchers about what neuroeducation as a specific domain do that no other field can do as well or cannot do at all. Based on the literature reviewed, neuroeducational research can be understood as an interdisciplinary endeavor to develop an insightful understanding and holistic picture of problems related to learning and education. It thus epistemologically is based on an integrated methodological pluralism paradigm. This requires researchers to understand multiple methods and methodologies and employ as they formulate their own research projects. Researchers have a critical role to play in providing systematic evidence and conclusions that are scientifically valid and reliable and educationally relevant and usable. One significant implication of this argument is the need to strengthen the quality of the research component in graduate programs of the field and train interested researchers in the identification and formulation of relevant research questions.

  5. Regional and detailed research studies for stone resources in Korea

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-01

    This report consists of 6 subjects. 1) A study on the potentiality of building stone development from granite mass within Pocheon area, Kyeonggi Province. 2) The research on the variance of color and glossiness by means of Weather-Ometer. 3) Regional research studies on granites in Gimje-Yeonggwang area. 4) A study on the industrialization of building stones and industrial stone crafts - Study on the causes of stone weathering. 5) Borehole radar survey at the granite quarry mine, Pocheon, Kyounggi province. 6) Borehole radar diffraction tomography. (author). refs., tabs., figs.

  6. Improving the production of applied health research findings: insights from a qualitative study of operational research.

    Science.gov (United States)

    Crowe, Sonya; Turner, Simon; Utley, Martin; Fulop, Naomi J

    2017-09-08

    Knowledge produced through applied health research is often of a form not readily accessible to or actionable by policymakers and practitioners, which hinders its implementation. Our aim was to identify research activities that can support the production of knowledge tailored to inform policy and practice. To do this, we studied an operational research approach to improving the production of applied health research findings. A 2-year qualitative study was conducted of the operational research contribution to a multidisciplinary applied health research project that was successful in rapidly informing national policy. Semi-structured interviews (n = 20) were conducted with all members of the project's research team and advisory group (patient and health professional representatives and academics). These were augmented by participant (> 150 h) and non-participant (> 15 h) observations focusing on the process and experience of attempting to support knowledge production. Data were analysed thematically using QSR NVivo software. Operational research performed a knowledge mediation role shaped by a problem-focused approach and an intent to perform those tasks necessary to producing readily implementable knowledge but outwith the remit of other disciplinary strands of the project. Three characteristics of the role were found to support this: engaging and incorporating different perspectives to improve services by capturing a range of health professional and patient views alongside quantitative and qualitative research evidence; rendering data meaningful by creating and presenting evidence in forms that are accessible to and engage different audiences, enabling them to make sense of it for practical use; and maintaining perceived objectivity and rigour by establishing credibility, perceived neutrality and confidence in the robustness of the research in order to unite diverse professionals in thinking creatively about system-wide service improvement. Our study

  7. Research Costs Investigated: A Study Into the Budgets of Dutch Publicly Funded Drug-Related Research.

    Science.gov (United States)

    van Asselt, Thea; Ramaekers, Bram; Corro Ramos, Isaac; Joore, Manuela; Al, Maiwenn; Lesman-Leegte, Ivonne; Postma, Maarten; Vemer, Pepijn; Feenstra, Talitha

    2018-01-01

    The costs of performing research are an important input in value of information (VOI) analyses but are difficult to assess. The aim of this study was to investigate the costs of research, serving two purposes: (1) estimating research costs for use in VOI analyses; and (2) developing a costing tool to support reviewers of grant proposals in assessing whether the proposed budget is realistic. For granted study proposals from the Netherlands Organization for Health Research and Development (ZonMw), type of study, potential cost drivers, proposed budget, and general characteristics were extracted. Regression analysis was conducted in an attempt to generate a 'predicted budget' for certain combinations of cost drivers, for implementation in the costing tool. Of 133 drug-related research grant proposals, 74 were included for complete data extraction. Because an association between cost drivers and budgets was not confirmed, we could not generate a predicted budget based on regression analysis, but only historic reference budgets given certain study characteristics. The costing tool was designed accordingly, i.e. with given selection criteria the tool returns the range of budgets in comparable studies. This range can be used in VOI analysis to estimate whether the expected net benefit of sampling will be positive to decide upon the net value of future research. The absence of association between study characteristics and budgets may indicate inconsistencies in the budgeting or granting process. Nonetheless, the tool generates useful information on historical budgets, and the option to formally relate VOI to budgets. To our knowledge, this is the first attempt at creating such a tool, which can be complemented with new studies being granted, enlarging the underlying database and keeping estimates up to date.

  8. Research capacity building in midwifery: Case study of an Australian Graduate Midwifery Research Intern Programme.

    Science.gov (United States)

    Hauck, Yvonne L; Lewis, Lucy; Bayes, Sara; Keyes, Louise

    2015-09-01

    Having the research capacity to identify problems, create new knowledge and most importantly translate this knowledge into practice is essential within health care. Midwifery, as well as other health professions in Australia, is challenged in building its research capacity to contribute evidence to inform clinical practice. The aim of this project was to evaluate an innovative Graduate Midwifery Research Intern Programme offered at a tertiary obstetric hospital in Western Australia, to determine what was working well and how the programme could be improved. A case study approach was used to gain feedback from graduate midwives within a Graduate Research Intern (GRI) Programme. In addition outcomes were compiled of all projects the GRI midwives contributed to. Six GRI midwives participated in a survey comprising of four open ended questions to provide feedback about the programme. Findings confirm that the GRI programme increased the graduates understanding of how research works, its capacity to define a problem, generate new knowledge and inform clinical practice. The GRI midwives' feedback suggested the programme opened their thinking to future study and gave them enhanced insight into women's experiences around childbirth. To grow our knowledge as a professional group, midwives must develop and promote programmes to build our pool of research capable midwives. By sharing our programme evaluation we hope to entice other clinical settings to consider the value in replicating such a programme within their context. Copyright © 2015 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.

  9. Open-Source Software in Computational Research: A Case Study

    Directory of Open Access Journals (Sweden)

    Sreekanth Pannala

    2008-04-01

    Full Text Available A case study of open-source (OS development of the computational research software MFIX, used for multiphase computational fluid dynamics simulations, is presented here. The verification and validation steps required for constructing modern computational software and the advantages of OS development in those steps are discussed. The infrastructure used for enabling the OS development of MFIX is described. The impact of OS development on computational research and education in gas-solids flow, as well as the dissemination of information to other areas such as geophysical and volcanology research, is demonstrated. This study shows that the advantages of OS development were realized in the case of MFIX: verification by many users, which enhances software quality; the use of software as a means for accumulating and exchanging information; the facilitation of peer review of the results of computational research.

  10. A Bibliometric Study on Culture Research in International Business

    Directory of Open Access Journals (Sweden)

    Claudia Frias Pinto

    2014-07-01

    Full Text Available National cultures and cultural differences provide a crucial component of the international business (IB research context. We conducted a bibliometric study of articles published in seven leading IB journals over a period of three decades to analyze how national culture has been impacting IB research. Co-citation mappings permit us to identify the ties binding works dealing with culture and cultural issues in IB. We identify two main clusters of research, each comprising two sub-clusters, with Hofstede’s (1980 work delineating much of the conceptual and empirical approach to culture-related studies. One main cluster entails works on the conceptualization of culture and its dimensions and the other cluster focuses on cultural distance. This conceptual framework captures the extant IB research incorporating culture-related concepts and influences.

  11. Research

    African Journals Online (AJOL)

    abp

    2016-02-01

    Feb 1, 2016 ... University Hospital, DK-5000 Odense, Denmark, 3Center for Global Health, Institute of Clinical Research, University of Southern Denmark, DK-5000. Odense .... BHP is a Danish-Guinean Demographic Surveillance Site with a study-area .... variables such as age groups, previous military duty, history of.

  12. Research

    African Journals Online (AJOL)

    abp

    2014-01-31

    Jan 31, 2014 ... by Hazarika in a population-based study in India. The researcher noted that patients' preference to the private health facilities was due mainly to their dissatisfaction with the services in the public health facilities [11]. Furthermore, the quality of the services in the private health facilities could also be a major ...

  13. Value of qualitative research in the study of massage therapy.

    Science.gov (United States)

    Kania, Ania; Porcino, Antony; Vehoef, Marja J

    2008-12-15

    Qualitative inquiry is increasingly used in health research because it is particularly suited to the study of complex topics or issues about which little is known and concerning which quantification cannot easily create or effectively convey understanding. By exploring the lived experience of people providing and receiving massage therapy and the meaning that those people ascribe to those experiences, in-depth understanding of the nature of massage therapy and of how it affects people's lives is possible. Qualitative research may also provide insights into the outcomes, process and context of massage therapy that cannot be fully achieved through quantification alone.The purpose of the present article is to describe qualitative research and to discuss its value to the massage therapy profession. The target audience is massage therapists who want to be able to better understand the research literature, novice massage therapy researchers who are unfamiliar with qualitative research, and teachers of research methods courses in massage therapy training programs who want to include qualitative research methods in their curriculum.

  14. Conceptual Study for development of a low power research reactor

    International Nuclear Information System (INIS)

    Park, C.; Kim, H. S.; Park, J. H.; Chae, H. T.; Lee, B. C.

    2013-01-01

    Even though the nuclear society is again facing with difficult situations after Fukusima accident, some countries still continues to consider nuclear power as one option of national energy sources and to introduce nuclear energy. As a research reactor has been regarded as a step-stone to establish infrastructures for the nuclear power development program, some countries that have plan to introduce the nuclear power energy are considering to construct a research reactor. Particularly, a low power research reactor whose main purpose is basic researches on the nuclear technology and education/training would be of interest to developing countries when taking the economy and level of science and technology into consideration. And many low power research reactors at operation are obsolescent and their numbers are decreasing. Hence, some concepts on a low power research reactor are being studied for the future needs. This paper presents the conceptual study on the basic requirements and the preliminary design features of a low power research reactor

  15. A Scoping Study on the Ethics of Health Systems Research.

    Science.gov (United States)

    Bachani, Abdulgafoor M; Rattani, Abbas; Hyder, Adnan A

    2016-12-01

    Currently, health systems research (HSR) is reviewed by the same ethical standards as clinical research, which has recently been argued in the literature to be an inappropriate standard of evaluation. The issues unique to HSR warrant a different review by research ethics committees (RECs), as it does not impose the same risks to study participants as other types of clinical or public health research. However, there are limited tools and supporting documents that clarify the ethical considerations. Therefore, there is a need for additional reflection around ethical review of HSR and their consideration by RECs. The purpose of this paper is to review, understand, and synthesize the current state of literature and practice to inform these deliberations and the larger discourse on ethics review guidelines for HSR. This paper presents a review of the literature on ethics of HSR in the biomedical, public health, and implementation research to identify ethical considerations specific to HSR; and to identify examples of commonly available guidance and/or tools for the ethical review of HSR studies. Fifteen articles were identified on HSR ethics issues, and forty-two international academic institutions were contacted (of the responses (n=29), no institution had special ethical guidelines for reviewing HSR) about their HSR ethics review guidelines. There appears to be a clear gap in the current health research ethics discourse around health systems research ethics. This review serves as a first step (to better understand the current status) towards a larger dialogue on the topic. © 2016 John Wiley & Sons Ltd.

  16. The Inclusion of African-American Study Participants in Web-Based Research Studies: Viewpoint

    OpenAIRE

    Watson, Bekeela; Robinson, Dana H.Z; Harker, Laura; Arriola, Kimberly R. Jacob

    2016-01-01

    The use of Web-based methods for research recruitment and intervention delivery has greatly increased as Internet usage continues to grow. These Internet-based strategies allow for researchers to quickly reach more people. African-Americans are underrepresented in health research studies. Due to this, African-Americans get less benefit from important research that could address the disproportionate health outcomes they face. Web-based research studies are one promising way to engage more Afri...

  17. Research output in medieval and crusades studies 1981-2011

    DEFF Research Database (Denmark)

    Nielsen, Torben Kjersgaard

    2017-01-01

    This article investigates the numerical research output of crusade studies over the past thirty years. The article compares its findings to the output of medieval studies in general in the same period. It shows in detail how the applied bibliometric statistics are generated and elaborates on some...... of the methodological considerations necessary in carrying out this kind of quantitative research. On the basis of bibliometric statistics generated from the International Medieval Bibliography (IMB) and Bibliographie de Civilisation Médiévale (BCM), the article identifies a numeric decrease in research output both...... in crusade studies in particular and in medieval studies in general. The article proposes further discussion on the “why” and “how” of this somewhat surprising result....

  18. Emerging Methodologies in Pediatric Palliative Care Research: Six Case Studies

    Directory of Open Access Journals (Sweden)

    Katherine E. Nelson

    2018-02-01

    Full Text Available Given the broad focus of pediatric palliative care (PPC on the physical, emotional, and spiritual needs of children with potentially life-limiting illnesses and their families, PPC research requires creative methodological approaches. This manuscript, written by experienced PPC researchers, describes issues encountered in our own areas of research and the novel methods we have identified to target them. Specifically, we discuss potential approaches to: assessing symptoms among nonverbal children, evaluating medical interventions, identifying and treating problems related to polypharmacy, addressing missing data in longitudinal studies, evaluating longer-term efficacy of PPC interventions, and monitoring for inequities in PPC service delivery.

  19. Emerging Methodologies in Pediatric Palliative Care Research: Six Case Studies

    Science.gov (United States)

    Nelson, Katherine E.; Gerhardt, Cynthia A.; Rosenberg, Abby R.; Widger, Kimberley; Faerber, Jennifer A.; Feudtner, Chris

    2018-01-01

    Given the broad focus of pediatric palliative care (PPC) on the physical, emotional, and spiritual needs of children with potentially life-limiting illnesses and their families, PPC research requires creative methodological approaches. This manuscript, written by experienced PPC researchers, describes issues encountered in our own areas of research and the novel methods we have identified to target them. Specifically, we discuss potential approaches to: assessing symptoms among nonverbal children, evaluating medical interventions, identifying and treating problems related to polypharmacy, addressing missing data in longitudinal studies, evaluating longer-term efficacy of PPC interventions, and monitoring for inequities in PPC service delivery. PMID:29495384

  20. French studies and research program in pressurized water reactor safety

    International Nuclear Information System (INIS)

    Duco, J.

    1986-06-01

    The aim of researches developed now in France on water reactor safety is to obtain means and knowledge allowing to control accidental situations, including severe situations beyond design basis accidents. The main studies and researches concerning water reactors and described in this report are the following ones: core cooling accident and prevention of severe accidents, fuel behavior in accidental situation, behavior of the containment building, fission product transfer and releases in case of accident, problems related to equipment aging, and, methodology of risk analysis and ''human factor'' studies. Most of these studies follow an analytic approach of phenomena [fr

  1. Enquiry Learning in Social Studies. ACER Research Series No. 101.

    Science.gov (United States)

    Whitehead, Graham

    Teaching enquiry methods, that is, skills concerned with constructing knowledge from available information and searching for new information, is the subject of this study, which provides a background to the subject as well as a review of research. The study sought to answer the question of whether problem-solving performances of primary school…

  2. Developing Critical Thinking through Socratic Questioning: An Action Research Study

    Science.gov (United States)

    Sahamid, Husniah

    2016-01-01

    An action research study was conducted among 24 Form 4 level Malaysian students, aged 16. The duration of the study was five months and constituted 16 one-hour literature lessons (short stories from the secondary level Malaysian English Language Upper Secondary Level school syllabus). This paper describes my experience as a teacher-as-researcher…

  3. Preparing School Leaders: Action Research on the Leadership Study Group

    Science.gov (United States)

    Kamler, Estelle

    2016-01-01

    This article reports an action research study that examined the Leadership Study Group, one learning activity designed to build knowledge and skills for aspiring school leaders and implemented in a six-credit introductory course for school leader certification. Through analysis of a variety of qualitative data collected over nine semesters, I…

  4. Journaling and Self-Study in an International Research Collective

    Science.gov (United States)

    Makaiau, Amber Strong; Leng, Lu; Fukui, Suguru

    2015-01-01

    Drawing from the theoretical foundations of reflective teaching, culturally responsive education, social constructivism, and self-study, this collaborative self-study investigates the role of an interactive online journal in an international research collective. Each from a different country, the authors came together through a common interest in…

  5. Institutional Repositories in Indian Universities and Research Institutes: A Study

    Science.gov (United States)

    Krishnamurthy, M.; Kemparaju, T. D.

    2011-01-01

    Purpose: The purpose of this paper is to report on a study of the institutional repositories (IRs) in use in Indian universities and research institutes. Design/methodology/approach: Repositories in various institutions in India were accessed and described in a standardised way. Findings: The 20 repositories studied covered collections of diverse…

  6. Researches in agri-food supply chain: A bibliometric study

    Science.gov (United States)

    Hisjam, Muhammad; Sutopo, Wahyudi

    2017-11-01

    Agri-food is very important for human being. Problems in managing agri-food are very complicated. There are many entities involved in managing agri-food with conflict of interest between them makes the problems become more complicated. Using supply chain approaches in agri-food will help solving the problems. The purpose of this paper is to show that the publications in agri-food supply chain research area are still promising and to show the research trend in agri-food supply chain. The study was a bibliometric study by using some queries on the website with the largest database of peer-reviewed literature. The queries were using various categories and refinements. Firstly the study was exploring all publications in this research area in some categories and then divided the duration into 2 intervals. The last query was to know how many publications are review type publications. The results show that the number of the publications with agri-food supply chain topics are still limited, and tend to increase. It means researches in this area are still promising. The results also show the most publications are from which source title, country, and affiliation. The results also show the research trend in this research area. The quantities of review type publications in agri-food supply chain are still few. It shows the need for more review type publications in this area.

  7. Sense and readability: participant information sheets for research studies.

    Science.gov (United States)

    Ennis, Liam; Wykes, Til

    2016-02-01

    Informed consent in research is partly achieved through the use of information sheets. There is a perception however that these information sheets are long and complex. The recommended reading level for patient information is grade 6, or 11-12 years old. To investigate whether the readability of participant information sheets has changed over time, whether particular study characteristics are related to poorer readability and whether readability and other study characteristics are related to successful study recruitment. Method: We obtained 522 information sheets from the UK National Institute for Health Research Clinical Research Network: Mental Health portfolio database and study principal investigators. Readability was assessed with the Flesch reading index and the Grade level test. Information sheets increased in length over the study period. The mean grade level across all information sheets was 9.8, or 15-16 years old. A high level of patient involvement was associated with more recruitment success and studies involving pharmaceutical or device interventions were the least successful. The complexity of information sheets had little bearing on successful recruitment. Information sheets are far more complex than the recommended reading level of grade 6 for patient information. The disparity may be exacerbated by an increasing focus on legal content. Researchers would benefit from clear guidance from ethics committees on writing succinctly and accessibly and how to balance the competing legal issues with the ability of participants to understand what a study entails. © The Royal College of Psychiatrists 2016.

  8. Salutogenic service user involvement in nursing research: a case study.

    Science.gov (United States)

    Mjøsund, Nina Helen; Vinje, Hege Forbech; Eriksson, Monica; Haaland-Øverby, Mette; Jensen, Sven Liang; Kjus, Solveig; Norheim, Irene; Portaasen, Inger-Lill; Espnes, Geir Arild

    2018-05-12

    The aim was to explore the process of involving mental healthcare service users in a mental health promotion research project as research advisors and to articulate features of the collaboration which encouraged and empowered the advisors to make significant contributions to the research process and outcome. There is an increasing interest in evaluating aspects of service user involvement in nursing research. Few descriptions exist of features that enable meaningful service user involvement. We draw on experiences from conducting research which used the methodology interpretative phenomenological analysis to explore how persons with mental disorders perceived mental health. Aside from the participants in the project, five research advisors with service user experience were involved in the entire research process. We applied a case study design to explore the ongoing processes of service user involvement. Documents and texts produced while conducting the project (2012-2016), as well as transcripts from multistage focus group discussions with the research advisors, were analysed. The level of involvement was dynamic and varied throughout the different stages of the research process. Six features: leadership, meeting structure, role clarification, being members of a team, a focus on possibilities and being seen and treated as holistic individuals, were guiding principles for a salutogenic service user involvement. These features strengthened the advisors' perception of themselves as valuable and competent contributors. Significant contributions from research advisors were promoted by facilitating the process of involvement. A supporting structure and atmosphere were consistent with a salutogenic service user involvement. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  9. Heterogeneity of Human Research Ethics Committees and Research Governance Offices across Australia: An observational study

    Directory of Open Access Journals (Sweden)

    Elisabeth De Smit

    2016-02-01

    Full Text Available Background Conducting ethically grounded research is a fundamental facet of all investigations. Nevertheless, the administrative burdens of current ethics review are substantial, and calls have been made for a reduction in research waste. Aims To describe the heterogeneity in administration and documentation required by Human Research Ethics Committees (HRECs and Research Governance Offices (RGOs across Australia. Methods In establishing a nationwide study to investigate the molecular aetiology of Giant Cell Arteritis (GCA, for which archived pathological specimens from around Australia are being recruited, we identified variation across separate HREC and RGO requirements. Submission paperwork and correspondence from each collaborating site and its representative office for research were reviewed. This data was interrogated to evaluate differences in current guidelines. Results Twenty-five pathology departments across seven Australian States collaborated in this study. All states, except Victoria, employed a single ethics review model. There was discrepancy amongst HRECs as to which application process applied to our study: seven requested completion of a “National Ethics Application Form” and three a “Low Negligible Risk” form. Noticeable differences in guidelines included whether electronic submission was sufficient. There was variability in the total number of documents submitted (range five to 22 and panel review turnaround time (range nine to 136 days. Conclusion We demonstrate the challenges and illustrate the heavy workload involved in receiving widespread ethics and governance approval across Australia. We highlight the need to simplify, homogenise, and nationalise human ethics for non-clinical trial studies. Reducing unnecessary administration will enable investigators to achieve research aims more efficiently

  10. What role do study and research activities play in the relation between research and education?

    DEFF Research Database (Denmark)

    Jessen, Britta Eyrich

    2015-01-01

    This paper presents a study organising the teaching of exponential functions in an attempt to re-establish a connection be- tween research and education (or school mathematics) based on the anthropological theory of the didactics (ATD). The teaching aims at students developing new knowledge like...

  11. Practical and Scholarly Implications of Information Behaviour Research: A Pilot Study of Research Literature

    Science.gov (United States)

    Koh, Kyungwon; Rubenstein, Ellen; White, Kelvin

    2015-01-01

    Introduction: This pilot study examined how current information behaviour research addresses the implications and potential impacts of its findings. The goal was to understand what implications and contributions the field has made and how effectively authors communicate implications of their findings. Methods: We conducted a content analysis of 30…

  12. Rethinking a Case Study Method in Educational Research: A Comparative Analysis Method in Qualitative Research

    Science.gov (United States)

    Murakami, Yusuke

    2013-01-01

    There are two types of qualitative research that analyze a small number of cases or a single case: idiographic differentiation and nomothetic/generalization. There are few case studies of generalization. This is because theoretical inclination is weak in the field of education, and the binary framework of quantitative versus qualitative research…

  13. Maximising the impact of qualitative research in feasibility studies for randomised controlled trials: guidance for researchers

    NARCIS (Netherlands)

    O’Cathain, A.; Hoddinott, P.; Lewin, S.; Thomas, K.J.; Young, B.; Adamson, J.; Jansen, J.F.M.; Mills, N.; Moore, G.; Donovan, J.L.

    2015-01-01

    Feasibility studies are increasingly undertaken in preparation for randomised controlled trials in order to explore uncertainties and enable trialists to optimise the intervention or the conduct of the trial. Qualitative research can be used to examine and address key uncertainties prior to a full

  14. Supporting research in area studies a guide for academic libraries

    CERN Document Server

    Pitman, Lesley

    2015-01-01

    Supporting Research in Area Studies: A Guide for Academic Libraries focuses on the study of other countries or regions of the world, crossing traditional disciplinary boundaries in the humanities and social sciences. The book provides a comprehensive guide for academic libraries supporting communities of researchers, exploring the specialist requirements of these researchers in information resources, resource discovery tools, information skills, and the challenges of working with materials in multiple languages. The book makes the case that adapting systems and procedures to meet these needs will help academic libraries be better placed to support their institutions' international agenda. Early chapters cover the academic landscape, its history, area studies, librarianship, and acquisitions. Subsequent chapters discuss collections management, digital products, and the digital humanities, and their role in academic projects, with final sections exploring information skills and the various disciplinary skills t...

  15. Sustainable operations in nuclear research reactors. A bibliographical study

    International Nuclear Information System (INIS)

    Kibrit, Eduardo; Rodrigues de Aquino, Afonso; Marotti de Mello, Adriana; Tromboni de Souza Nascimento, Paulo

    2017-01-01

    Sustainability is gaining prominence in the area of operations management. By means of a bibliographical research, we identified in literature sustainable operations carried out by operating organizations of nuclear research reactors. The methodology applied consisted in gathering material, descriptive analysis, selection of analytical categories and evaluation of the material collected. The collection of material was performed by a search made on academic and nuclear databases, with keywords structured for the subject of the research. The collected material was analysed and analytical categories on the theme sustainable operations were established. The evaluation of the collected material resulted in references accepted for the study, classified according to the pre-established analytical categories. The results were significant. From then on, a theoretical review on the topic under study was structured, based on pre-defined analytical categories. Thus, we were able to identify gaps in the literature and propose new studies on the subject.

  16. Sustainable operations in nuclear research reactors. A bibliographical study

    Energy Technology Data Exchange (ETDEWEB)

    Kibrit, Eduardo; Rodrigues de Aquino, Afonso [Cidade Univ., Sao Paolo (Brazil). Inst. de Pesquisas Energeticas e Nucleares; Marotti de Mello, Adriana [Sao Paolo Univ. (Brazil). Faculdade de Economia; Tromboni de Souza Nascimento, Paulo [Sao Paolo Univ. (Brazil). Faculdade de Economia Administracao e Contabilidade

    2017-10-15

    Sustainability is gaining prominence in the area of operations management. By means of a bibliographical research, we identified in literature sustainable operations carried out by operating organizations of nuclear research reactors. The methodology applied consisted in gathering material, descriptive analysis, selection of analytical categories and evaluation of the material collected. The collection of material was performed by a search made on academic and nuclear databases, with keywords structured for the subject of the research. The collected material was analysed and analytical categories on the theme sustainable operations were established. The evaluation of the collected material resulted in references accepted for the study, classified according to the pre-established analytical categories. The results were significant. From then on, a theoretical review on the topic under study was structured, based on pre-defined analytical categories. Thus, we were able to identify gaps in the literature and propose new studies on the subject.

  17. Measuring research impact in medical research institutes: a qualitative study of the attitudes and opinions of Australian medical research institutes towards research impact assessment frameworks.

    Science.gov (United States)

    Deeming, Simon; Reeves, Penny; Ramanathan, Shanthi; Attia, John; Nilsson, Michael; Searles, Andrew

    2018-03-16

    The question of how to measure, assess and optimise the returns from investment in health and medical research (HMR) is a highly policy-relevant issue. Research Impact Assessment Frameworks (RIAFs) provide a conceptual measurement framework to assess the impact from HMR. The aims of this study were (1) to elicit the views of Medical Research Institutes (MRIs) regarding objectives, definitions, methods, barriers, potential scope and attitudes towards RIAFs, and (2) to investigate whether an assessment framework should represent a retrospective reflection of research impact or a prospective approach integrated into the research process. The wider objective was to inform the development of a draft RIAF for Australia's MRIs. Purposive sampling to derive a heterogeneous sample of Australian MRIs was used alongside semi-structured interviews with senior executives responsible for research translation or senior researchers affected by research impact initiatives. Thematic analysis of the interview transcriptions using the framework approach was then performed. Interviews were conducted with senior representatives from 15 MRIs. Participants understood the need for greater research translation/impact, but varied in their comprehension and implementation of RIAFs. Common concerns included the time lag to the generation of societal impacts from basic or discovery science, and whether impact reflected a narrow commercialisation agenda. Broad support emerged for the use of metrics, case study and economic methods. Support was also provided for the rationale of both standardised and customised metrics. Engendering cultural change in the approach to research translation was acknowledged as both a barrier to greater impact and a critical objective for the assessment process. Participants perceived that the existing research environment incentivised the generation of academic publications and track records, and often conflicted with the generation of wider impacts. The potential to

  18. Study to define NDE research for inspection of stainless steels

    International Nuclear Information System (INIS)

    Reinhart, E.R.

    1978-08-01

    After the boiling water reactor (BWR) stress corrosion cracking incidents on 4- and 10-inch stainless steel piping, the Electric Power Research Institute (EPRI) organized a round-robin ultrasonic examination of piping removed from service (TPS-75-609). Five inspection teams participated in this program, using both a standard procedure and the individual team procedure. The original intent was to section the piping after the program to evaluate the effectiveness of state-of-the-art ultrasonics in finding stress corrosion cracking. The sectioning was delayed, however, to allow research and development (R and D) groups time to perform basic measurements aimed at determining optimum search unit and instrument characteristics for the ultrasonic examination of stainless steel piping and to study the applicability of various advanced inspection methods. This additional effort was funded as part of an EPRI technical planning study (TPS-75-620), A Study to Define NDE Research for Inspection of Stainless Steels. Inspection methods evaluated in this study included (1) processing of manual scan data using a miniature programmable calculator (Aerojet Nuclear); (2) investigation into the performance characteristics of three experimental ultrasonic transducers (Battelle-Columbus Laboratories); (3) analysis of fundamental ultrasonic response data from intergranular stress corrosion cracks in stainless steels (Southwest Research Institute); and (4) a feasibility study of advanced signal processing and pattern recognition for analyzing flaws in stainless steel piping (Ultrasonics International). The results of the studies compiled in the report have indicated the direction for future research and development and have formed the basis for the recently initiated EPRI Research Project 892, Ultrasonic System Optimization

  19. A pilot study of MD (psychiatry) theses-based research.

    Science.gov (United States)

    Srivastava, Shrikant; Agarwal, Vivek; Subramanyam, Alka; Srivastava, Mona; Sathyanarayana Rao, T S; Rao, G Prasad; Khurana, Hitesh; Singh, Archana

    2018-01-01

    Undertaking a research project is mandatory for MD Psychiatry trainees. The present study was undertaken to assess the type of research activity being undertaken as part of MD Psychiatry dissertation, and its contribution to national and international literature. Three medical colleges supplied the data about the topic, names of the supervisor and the candidate, collaboration, funding accrued, and publication details of MD-based research carried out between years 2000 and 2010 inclusive; 95 records were collected for the final analysis. The details of the publications provided were cross-checked on the internet, which would have taken care of missed publications as well. Most studies were single-point assessment clinical studies. Only 2 studies had been funded, 11 had collaboration with other departments within the same institute, and 5 had inter-institute collaborations. Majority of the studies were not published. Only 30 were published as full paper and 9 as abstracts. Of these 30 full publications, only 3 were published in journals having JCI impact factor values (1.4, 1.3, and 1.4, respectively). The main finding of this pilot study was that MD-based research has low contribution to the national and international literature, and those articles which are published are in low impact journals. Suggestions for modifying this state of affairs are discussed.

  20. Delayed age at transfer of adoptees to adoptive parents is associated with increased mortality irrespective of social class of the adoptive parents: a cohort study.

    Science.gov (United States)

    Petersen, Liselotte; Andersen, Per Kragh; Sørensen, Thorkild I A; Mortensen, Erik Lykke

    2018-04-24

    Adverse early life experience and development may have long-term health consequences, but later environmental conditions may perhaps protect against the effects of such early life adversities. The aim was to investigate whether cause-specific and overall mortality rates among adoptees are associated with the age at which they were transferred to the adoptive family and whether the social class of the adoptive family modifies this association. A cohort of 10,592 non-familial adoptions (biologically unrelated adoptee and adoptive parents) of Danish-born children formally granted in 1924-47 and with follow-up of total and cause-specific mortality through ages up to 85 years. The rates of death after the age of 16 from all causes combined, all natural causes, all external causes, and suicide were compared according to the age at which adoptees were transferred to their adoptive family by estimating hazard ratios in Cox regression models. Death rates from all causes were significantly higher in adoptees transferred between age 1 month and 4 years compared to those transferred immediately after birth with the hazard ratio peaking at 1.19 (95% confidence limit: 1.08 to 1.32) for adoptees transferred between 6 and 11 months. This result was primarily driven by a similar pattern for natural causes of death. For death from external causes and for suicide the hazard ratios were increasing with increasing age at transfer, and tests for trend were statistically significant. The social class of the adoptive family did not significantly modify these associations. Transfer to an adoptive family later than at the time of birth may have adverse long-term consequences affecting overall and cause-specific mortality. These effects were not modified by the environment provided by the adoptive family as indicated by the social class of these families.

  1. Research study of conjugate materials; Conjugate material no chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The paper reported an introductory research on possibilities of new glass `conjugate materials.` The report took up the structure and synthetic process of conjugate materials to be researched/developed, classified them according to structural elements on molecular, nanometer and cluster levels, and introduced the structures and functions. Further, as glasses with new functions to be proposed, the paper introduced transparent and high-strength glass used for houses and vehicles, light modulation glass which realizes energy saving and optical data processing, and environmentally functional glass which realizes environmental cleaning or high performance biosensor. An initial survey was also conducted on rights of intellectual property to be taken notice of in Japan and abroad in the present situation. Reports were summed up and introduced of Osaka National Research Institute, Electrotechnical Laboratory, and National Industrial Research Institute of Nagoya which are all carrying out leading studies of conjugate materials. 235 refs., 135 figs., 6 tabs.

  2. Retention of minority participants in clinical research studies.

    Science.gov (United States)

    Keller, Colleen S; Gonzales, Adelita; Fleuriet, K Jill

    2005-04-01

    Recruitment of minority participants for clinical research studies has been the topic of several analytical works. Yet retention of participants, most notably minority and underserved populations, is less reported and understood, even though these populations have elevated health risks. This article describes two related, intervention-based formative research projects in which researchers used treatment theory to address issues of recruitment and retention of minority women participants in an exercise program to reduce obesity. Treatment theory incorporates a model of health promotion that allows investigators to identify and control sources of extraneous variables. The authors' research demonstrates that treatment theory can improve retention of minority women participants by considering critical inputs, mediating processes, and substantive participant characteristics in intervention design.

  3. CRL research reactor diesel generator reliability study 1960 - 1992

    International Nuclear Information System (INIS)

    Winfield, D.J.; McCauley, G.M.

    1994-07-01

    A data base has been provided for the Chalk River Laboratories (CRL) research reactor diesel generator reliability, for use in risk assessment studies of CRL research reactors. Data from 1960 to end of 1992 have been collected, representing 358 diesel generator years of experience. The data is used to provide failure-to-start probabilities and failure-to-run rates. Data is also classified according to subsystem failures, multiple failures and common cause failures. Comparisons with other recent studies of nuclear power plant diesel generator reliability have been made. This revision updates the 1989 September report. (author). 14 refs., 13 tabs., 10 figs

  4. CRNL research reactor diesel generator reliability study 1960-1985

    International Nuclear Information System (INIS)

    Winfield, D.J.

    1989-09-01

    A data base has been provided for the CRNL research reactor diesel generator reliability, for use in risk assessment studies of CRNL research reactors. Data from 1960 to the present have been collected, representing 281 diesel generator years of experience. The data is used to provide failure-to-start probabilities and failure-to-run rates. Data is also classified according to subsystem failures, multiple failures and common cause failures. Comparisons with other recent studies of nuclear power plant diesel generator reliability have been made

  5. The HSP90 inhibitor 17-AAG synergizes with doxorubicin and U0126 in anaplastic large cell lymphoma irrespective of ALK expression.

    Science.gov (United States)

    Georgakis, Georgios V; Li, Yang; Rassidakis, Georgios Z; Medeiros, L Jeffrey; Younes, Anas

    2006-12-01

    Heat shock protein 90 (HSP90) chaperones and maintains the molecular integrity of a variety of signal transduction proteins, including the nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) oncogenic protein, a genetic abnormality that is frequently observed in anaplastic large cell lymphoma (ALCL) cells. Here we demonstrate that HSP90 is overexpressed in primary and cultured ALK-positive and ALK-negative ALCL cells, and we evaluate the potential role of the small molecule inhibitor of HSP90, 17-allylamino-17-demethoxygeldanamycin (17-AAG) in treating ALCL. The antiproliferative effect of 17-AAG-cultured cells was determined by MTS assay. Apoptosis and cell-cycle arrest were determined by Annexin-V/propidium iodide and propidium iodide staining, respectively, and fluorescein-activated cell sorting analysis. Expression of HSP90 was evaluated by immunohistochemistry, and molecular changes were determined by Western blot. Treatment of cultured ALCL cells with 17-AAG induced cell-cycle arrest and apoptosis, irrespective of ALK expression. At the molecular level, 17-AAG induced degradation of ALK and Akt proteins, dephosphorylated extracellular signal-regulated kinase, and degraded the cell-cycle regulatory protein cyclin D1 and its cyclin-dependent kinases, CDK4 and CDK6, but had a differential effect on p27 and p53 proteins. Inhibition of extracellular signal-regulated kinase phosphorylation by the mitogen activated protein kinase inhibitor U0126 induced cell death in all ALCL cell lines, and sublethal concentration 17-AAG showed synergistic antiproliferative effects when combined with U0126 or doxorubicin. Our data demonstrate that targeting HSP90 function by 17-AAG may offer a novel therapeutic strategy for ALCL, either as single-agent activity or by combining 17-AAG with conventional or targeted therapeutic schemes.

  6. A mixed method pilot study: the researchers' experiences.

    Science.gov (United States)

    Secomb, Jacinta M; Smith, Colleen

    2011-08-01

    This paper reports on the outcomes of a small well designed pilot study. Pilot studies often disseminate limited or statistically meaningless results without adding to the body knowledge on the comparative research benefits. The design a pre-test post-test group parallel randomised control trial and inductive content analysis of focus group transcripts was tested specifically to increase outcomes in a proposed larger study. Strategies are now in place to overcome operational barriers and recruitment difficulties. Links between the qualitative and quantitative arms of the proposed larger study have been made; it is anticipated that this will add depth to the final report. More extensive reporting on the outcomes of pilot studies would assist researchers and increase the body of knowledge in this area.

  7. 76 FR 23605 - New Proposed Collection; Comment Request; Study Logistic Formative Research Methodology Studies...

    Science.gov (United States)

    2011-04-27

    ...; Comment Request; Study Logistic Formative Research Methodology Studies for the National Children's Study... maximize the efficiency (measured by scientific robustness, participant and infrastructure burden, and cost... assess the feasibility, acceptability, and cost of the recruitment strategy, study procedures, and...

  8. Implementation of Subjective Cognitive Decline criteria in research studies

    Science.gov (United States)

    Molinuevo, José L; Rabin, Laura A.; Amariglio, Rebecca; Buckley, Rachel; Dubois, Bruno; Ellis, Kathryn A.; Ewers, Michael; Hampel, Harald; Klöppel, Stefan; Rami, Lorena; Reisberg, Barry; Saykin, Andrew J.; Sikkes, Sietske; Smart, Colette M.; Snitz, Beth E.; Sperling, Reisa; van der Flier, Wiesje M.; Wagner, Michael; Jessen, Frank

    2017-01-01

    INTRODUCTION Subjective Cognitive Decline (SCD) manifesting prior to clinical impairment could serve as a target population for early intervention trials in Alzheimer’s disease (AD). A working group, the Subjective Cognitive Decline Initiative (SCD-I), published SCD research criteria in the context of preclinical AD. To successfully apply them, a number of issues regarding assessment and implementation of SCD needed to be addressed. METHODS Members of the SCD-I met to identify and agree upon topics relevant to SCD criteria operationalization in research settings. Initial ideas and recommendations were discussed with other SCD-I working group members and modified accordingly. RESULTS Topics included SCD inclusion and exclusion criteria, together with the informant’s role in defining SCD presence and the impact of demographic factors. DISCUSSION Recommendations for the operationalization of SCD in differing research settings, with the aim of harmonization of SCD measurement across studies are proposed, to enhance comparability and generalizability across studies. PMID:27825022

  9. Research Centre for the Study of the Rogue Waves

    Science.gov (United States)

    Shamin, Roman

    2013-04-01

    In 2012, in Sakhalin (Russia) was established Research Center for the Study of the Rogue Waves. This center unites many known scientists, who study rogue waves. The center is founded by the following scientific organizations: - The Institute of Marine Geology and Geophysics of FEB RAS - The Far Eastern Federal University - Special Research Bureau for Automation of Marine Researches of FEB RAS - The Institute of Applied Physics of RAS - Shirshov Institute of Oceanology of RAS Heads this center Dr. Roman V. Shamin (Russia). Topics projects: - Probability of emergence of rogue waves - Finding of the sites of the Ocean most dangerous from the point of view of rogue waves - Assessment of risk of dangerous impact of rogue waves - and many others... Our Center is open for new participants from all countries. Our Centre have web-site: roguewaves.ru For contacts: center@roguewaves.ru (Dr. Roman Shamin)

  10. Primary prevention research: a preliminary review of program outcome studies.

    Science.gov (United States)

    Schaps, E; Churgin, S; Palley, C S; Takata, B; Cohen, A Y

    1980-07-01

    This article reviews 35 drug abuse prevention program evaluations employing drug-specific outcome measures. Many of these evaluations assessed the effects of "new generation" prevention strategies: affective, peer-oriented, and multidimensional approaches. Only 14 studies evaluated purely informational programs. Evaluations were analyzed to ascertain (1) characteristics of the programs under study, (2) characteristics of the research designs, and (3) patterns among findings. This review provides some evidence that the newer prevention strategies may produce more positive and fewer negative outcomes than did older drug information approaches. Over 70% of the programs using the newer strategies produced some positive effects; only 29% showed negative effects. In contrast, 46% of informational programs showed positive effects; 46% showed negative effects. These findings must be approached with great caution, since the research was frequently scientifically inadequate, and since rigor of research was negatively correlated with intensity and duration of program services.

  11. Participant Action Research in Political, Psychological, and Gender Studies

    Directory of Open Access Journals (Sweden)

    Olga Lucia Obando-Salazar

    2006-09-01

    Full Text Available Qualitative methodology is used in social and intervention research because it facilitates a deeper analysis of causal factors and development of alternative solutions to social problems. Based on the findings of three studies in the field of political and gender psychology, this article focuses on Participant Action Research (PAR as a useful qualitative approach to deal with social phenomena, such as racism, violence against women, and the problem of children and youth who have been dislocated as the result of armed conflict and sheltered by the Colombian government's program for persons relocated to civil society. This article is composed of three parts. The first part offers historical and theoretical background to the Action Research (AR paradigm, its validation criteria and their meaning for the development of the Latin American rendering of Participant Action Research (PAR. The second part synthesizes trends in the AR approach in the United States and Germany, discusses feminist research and compares these to trends in PAR in Latin America. The third part is a description of Participant Action Research as an intervention method, including features, models, goals, and concepts. URN: urn:nbn:de:0114-fqs060438

  12. American Indian Studies. Library Research Guide. 2nd Edition.

    Science.gov (United States)

    White, Phillip M.

    This guide to sources for San Diego (California) State University students doing library research on topics related to American Indian Studies begins by noting that information on North American Indians can be found in a variety of subject disciplines including history, anthropology, education, sociology, health care, law, business, and politics.…

  13. A Study on Research Trend in Nuclear Forensics

    International Nuclear Information System (INIS)

    Kim, Kyungmin; Yim, Hobin; Lee, Seungmin; Hong, Yunjeong; Kim, Jae Kwang

    2014-01-01

    The international community has recognized the serious threat posed by nuclear and other radioactive material out of regulatory control. To address these concerns, the Office of Nuclear Security of the international Atomic Energy Agency (IAEA) is developing, inter alia, guidance for nuclear forensics to assist Member States. According to the IAEA Incident and Trafficking Database (ITDB) of the IAEA to record the illegal trade and trafficking incidents of nuclear material or other radioactive material, incidents of 2331 have been reported in 1993 to 2012. These incidents mean that we are not safe for nuclear material. In order to solve the case generated by the illicit trafficking of nuclear material and the efficient management of nuclear material, the study of nuclear forensics is very important. In this study, we investigated the analytical techniques and the current status of nuclear forensics research. In this study, we investigated the current status of research of nuclear forensics, procedures for analysis and nuclear forensics analysis technique. A result of the study, we have been found that the major institutes and laboratory actively research on analysis technique and nuclear forensics. However, research on nuclear forensics is still in early stage, ROK is necessary preliminary survey of analysis technique and foundation of physical, chemical, and morphology characteristics of nuclear materials

  14. The need for interdisciplinary research in personality studies

    NARCIS (Netherlands)

    Van Oers, K.

    2007-01-01

    The target paper demonstrates the value of evolutionary genetics for personality research. Apart from a summing-up of concepts, the authors validate their theory with evidence from studies on both human- and animal personality. In this commentary, I want to show the need for inter-disciplinary

  15. Kartini Research Reactor prospective studies for neutron scattering application

    International Nuclear Information System (INIS)

    Widarto

    1999-01-01

    The Kartini Research Reactor (KRR) is located in Yogyakarta Nuclear Research Center, Yogyakarta - Indonesia. The reactor is operated for 100 kW thermal power used for research, experiments and training of nuclear technology. There are 4 beam ports and 1 column thermal are available at the reactor. Those beam ports have thermal neutron flux around 10 7 n/cm 2 s each other and used for sub critical assembly, neutron radiography studies and Neutron Activation Analysis (NAA). Design of neutron collimator has been done for piercing radial beam port and the calculation result of collimated neutron flux is around 10 9 n/cm 2 s. This paper describes experiment facilities and parameters of the Kartini research reactor, and further more the prospective studies for neutron scattering application. The purpose of this paper is to optimize in utilization of the beam ports facilities and enhance the manpower specialty. The special characteristic of the beam ports and preliminary studies, pre activities regarding with neutron scattering studies for KKR is presented. (author)

  16. The Value of Mixed Methods Research: A Mixed Methods Study

    Science.gov (United States)

    McKim, Courtney A.

    2017-01-01

    The purpose of this explanatory mixed methods study was to examine the perceived value of mixed methods research for graduate students. The quantitative phase was an experiment examining the effect of a passage's methodology on students' perceived value. Results indicated students scored the mixed methods passage as more valuable than those who…

  17. Concussion Awareness Education: A Design and Development Research Study

    Science.gov (United States)

    Pilbeam, Renee M.

    2016-01-01

    This research study looks at the design and development of an online concussion awareness education module. The Keep Your Head in the Game: Concussion Awareness Training for High School Athletes, or Brainbook, is a stand-alone e-learning module designed to run for fifty minutes and to be highly interactive using short video clips with associated…

  18. Maintenance Research in SOA Towards a Standard Case Study

    NARCIS (Netherlands)

    Espinha, T.; Chen, C.; Zaidman, A.E.; Gross, H.G.

    2012-01-01

    Preprint of paper published in: 16th European Conference on Software Maintenance and Reengineering (CSMR), 27-30 March 2012; doi:10.1109/CSMR.2012.49 Maintenance research in the context of Service Oriented Architecture (SOA) is currently lacking a suitable standard case study that can be used by

  19. Exploring Aging Attitudes through a Puppet Making Research Study

    Science.gov (United States)

    Whiteland, Susan R.

    2016-01-01

    Intergenerational programs often reduce ageism and stereotypical thinking. This author uses a mixed methods case study to investigate how attitudes may change when older adults and children participate in an intergenerational art project. The research question, "Is there a positive correlation in children's attitudes toward older adults and…

  20. Developing Multilingual Pedagogies and Research through Language Study and Reflection

    Science.gov (United States)

    Catalano, Theresa; Shende, Madhur; Suh, Emily K.

    2018-01-01

    Globalisation and increased transnational migration underscore the need for educational responses to multilingualism and multilingual discourses. One way to heighten awareness of multilingual pedagogies (while simultaneously providing data for multilingual research) is the use of reflective language study and journaling by language…

  1. Flipped Classroom Research and Trends from Different Fields of Study

    Science.gov (United States)

    Zainuddin, Zamzami; Halili, Siti Hajar

    2016-01-01

    This paper aims to analyse the trends and contents of flipped classroom research based on 20 articles that report on flipped learning classroom initiatives from 2013-2015. The content analysis was used as a methodology to investigate methodologies, area of studies, technology tools or online platforms, the most frequently used keywords and works…

  2. Researchers study decontamination of chemical, biological warfare agents

    OpenAIRE

    Trulove, Susan

    2007-01-01

    The U.S. Army Research Office has awarded Virginia Tech a $680,000 grant over two years to build an instrument that can be used to study the chemistry of gases that will decompose both chemical and biological warfare agents on surfaces.

  3. Developing critical thinking through Socratic Questioning: An Action Research Study

    Directory of Open Access Journals (Sweden)

    Husniah Sahamid

    2016-07-01

    Full Text Available An action research study was conducted among 24 Form 4 level Malaysian students, aged 16. The duration of the study was five months and constituted 16 one-hour literature lessons (short stories from the secondary level Malaysian English Language Upper Secondary Level school syllabus. This paper describes my experience as a teacher-as-researcher to assist students to respond to teacher questions through Paul’s (1993 model of Socratic Questioning which claims to develop students’ critical thinking. Data was collected through researcher’s field notes, students’ writing tasks and student interviews which were analysed after each cycle of the action research study. Changes and adaptations were consequently made based on the data collected and upon teacher reflection to improve practice. The results of this study indicate that repeated practice of Socratic Questioning had a positive effect on student responses and writing tasks. Some of the factors affecting students’ performance included students’ language proficiency, weak reading ability and students’ anxiety towards the questioning method. These issues had to be addressed and dealt with, before Socratic Questioning could be properly implemented in the classroom. Keywords: Socratic questioning, teacher questioning, critical thinking, action research

  4. Case Studies of Action Research in Various Adult Education Settings.

    Science.gov (United States)

    Kuhne, Gary W.; Weirauch, Drucie; Fetterman, David J.; Mearns, Raiana M.; Kalinosky, Kathy; Cegles, Kathleen A.; Ritchey, Linda

    1997-01-01

    Six case studies illustrate action research in adult education: faculty development in a museum, participation in a church congregation, retention of literacy volunteers in a corrections center, learner participation in a homeless shelter, technology innovation in a university, and infection control in a hospital. (SK)

  5. Research Review of the Institute of African Studies: Contact

    African Journals Online (AJOL)

    Principal Contact. Prof. M.E. Kropp Dakubu Editor-in-Chief University of Ghana. Research Review. Institute of African Studies. P.O.Box LG73 Legon, Ghana. Phone: 211-24-4764006. Fax: 233-21-500512. Email: medakubu@ug.edu.gh. Support Contact. Dr Stephen Acheampong Phone: 211-24-4979233

  6. Paper use in research ethics applications and study conduct.

    Science.gov (United States)

    Chakladar, Abhijoy; Eckstein, Sue; White, Stuart M

    2011-02-01

    Application for Research Ethics Committee (REC) approval and the conduct of medical research is paper intensive. This retrospective study examined all applications to a single REC in the south of England over one year. It estimated the mass of paper used, comparing the proportional paper consumption of different trial types and during different stages of the research process, quantifying the consumption in terms of carbon dioxide emissions. In 2009, 68 trials were submitted to the REC. Total paper consumption for the REC process and study conduct was 176,150 sheets of A4 paper (879 kg), equivalent to an estimated 11.5 million sheets (88 tonnes, 2100 trees) a year for the U.K.; the REC process accounted for 26.4%. REC applications and the conduct of approved trials generate considerable environmental impact through paper consumption contributing to the NHS's carbon footprint. Paper use might be reduced through the implementation of digital technologies and revised research methods, namely changing attitudes in both researchers and ethics committees.

  7. An Undergraduate Research Experience on Studying Variable Stars

    Science.gov (United States)

    Amaral, A.; Percy, J. R.

    2016-06-01

    We describe and evaluate a summer undergraduate research project and experience by one of us (AA), under the supervision of the other (JP). The aim of the project was to sample current approaches to analyzing variable star data, and topics related to the study of Mira variable stars and their astrophysical importance. This project was done through the Summer Undergraduate Research Program (SURP) in astronomy at the University of Toronto. SURP allowed undergraduate students to explore and learn about many topics within astronomy and astrophysics, from instrumentation to cosmology. SURP introduced students to key skills which are essential for students hoping to pursue graduate studies in any scientific field. Variable stars proved to be an excellent topic for a research project. For beginners to independent research, it introduces key concepts in research such as critical thinking and problem solving, while illuminating previously learned topics in stellar physics. The focus of this summer project was to compare observations with structural and evolutionary models, including modelling the random walk behavior exhibited in the (O-C) diagrams of most Mira stars. We found that the random walk could be modelled by using random fluctuations of the period. This explanation agreed well with observations.

  8. Participants' safety versus confidentiality: A case study of HIV research.

    Science.gov (United States)

    Leyva-Moral, Juan Manuel; Feijoo-Cid, Maria

    2017-05-01

    Background When conducting qualitative research, participants usually share lots of personal and private information with the researcher. As researchers, we must preserve participants' identity and confidentiality of the data. Objective To critically analyze an ethical conflict encountered regarding confidentiality when doing qualitative research. Research design Case study. Findings and discussion one of the participants in a study aiming to explain the meaning of living with HIV verbalized his imminent intention to commit suicide because of stigma of other social problems arising from living with HIV. Given the life-threatening situation, the commitment related to not disclosing the participant's identity and/or the content of the interview had to be broken. To avoid or prevent suicide, the therapist in charge of the case was properly informed about the participant's intentions. One important question arises from this case: was it ethically appropriate to break the confidentiality commitment? Conclusion confidentiality could be broken if a life-threatening event is identified during data collection and participants must know that. This has to be clearly stated in the informed consent form.

  9. Research study on antiskid braking systems for the space shuttle

    Science.gov (United States)

    Auselmi, J. A.; Weinberg, L. W.; Yurczyk, R. F.; Nelson, W. G.

    1973-01-01

    A research project to investigate antiskid braking systems for the space shuttle vehicle was conducted. System from the Concorde, Boeing 747, Boeing 737, and Lockheed L-1011 were investigated. The characteristics of the Boeing 737 system which caused it to be selected are described. Other subjects which were investigated are: (1) trade studies of brake control concepts, (2) redundancy requirements trade study, (3) laboratory evaluation of antiskid systems, and (4) space shuttle hardware criteria.

  10. The 100 top-cited tuberculosis research studies.

    Science.gov (United States)

    Chen, L-M; Liu, Y-Q; Shen, J-N; Peng, Y-L; Xiong, T-Y; Tong, X; Du, L; Zhang, Y-G

    2015-06-01

    The examination of top-cited studies is a useful method for identify and monitoring outstanding scientific research. The objective of this study was to identify and analyse the characteristics of the top 100 cited research studies on tuberculosis (TB) based on the Web of Knowledge. Overall, the top 100 cited studies were cited between 366 and 4443 times, and were published between 1995 and 2010, with the largest number of publications in 2003 and in 1995. Four studies were attributed to a single author and 10 to two authors; the number of authors exceeded six in 50 studies. Nine authors had more than one study as the first author and 18 authors had more than one study as the corresponding author. The United States contributed the largest number of studies, followed by the United Kingdom and France. The institutions with the largest number of articles were the Institut National de la Santé et de la Recherche Médicale in France and the University of California in the United States. The studies appeared in 35 journals, with 11 published in Science, followed by PNAS and NEJM. The majority of TB articles have been published in those medical journals with the highest impact factors, and are from the most industrialised countries.

  11. Recent trends in user studies: action research and qualitative methods

    Directory of Open Access Journals (Sweden)

    T.D. Wilson

    1998-01-01

    Full Text Available This paper was commissioned by Professor Gernot Wersig of the Freie Universität, Berlin in 1980, as part of his Project, Methodeninstrumentarium zur Benutzforschung in Information und Dokumentation. It attempted to set out what was, for the time, a novel perspective on appropriate methodologies for the study of human information seeking behaviour, focusing on qualitative methods and action research, arguing that the application of information research depended up its adoption into the managerial processes of organizations, rather than its self-evident relationship to any body of theory.

  12. Research and development studies on human factors: new trends

    International Nuclear Information System (INIS)

    Llory, M.; Larchier-Boulanger, J.

    1988-01-01

    This paper is aimed at describing where the research work on human factors undertaken at EDF stands in relation to this European trend and to define the problematics of cognitive phenomena in relation to all (non cognitive) human phenomena, on the one hand, and to individual aspects as compared to collective and organizational aspects, on the other. Some important trends in the research and development studies will thus be examined one lay one: - analysis of operators' activity; - analysis of the activity cognitive aspects; - problem of the impact of non-cognitive aspects

  13. Study and Research Paths at Upper Secondary Mathematics Education

    DEFF Research Database (Denmark)

    Jessen, Britta Eyrich

    the scope of teaching at this level. With respect to mathematical modelling, links and gaps were identified between scholarly knowledge and knowledge to be taught in secondary school. It is suggested that SRP based teaching can bridge parts of the identified gaps. Finally, it is found that in order for SRP......In didactics of mathematics, researchers have for decades been interested in how to teach students to pose questions and solve problems. Several approaches rely on the idea, that students learn mathematics, when they are engaged in activities similar to research mathematicians. This PhD project...... touch upon these ideas from the perspective offered by the Anthropological Theory of Didactics (ATD ). Within ATD, teaching is proposed to be designed as Study and Research Paths (SRP). This thesis investigates how SRP's support the students' learning of mathematics in a bidisciplinary context involving...

  14. The CRC Contribution to Research Training: Report of a Scoping Study for the Cooperative Research Centres Association

    Science.gov (United States)

    Palmer, Nigel

    2012-01-01

    This report summarises findings from a scoping study conducted for the Cooperative Research Centres Association (CRCA) by the Centre for the Study of Higher Education. The purpose of the scoping study is to inform the research training activities of Cooperative Research Centres (CRCs). While previous studies have focussed on the outcomes supported…

  15. Study of research needs and priorities in radioactive waste management

    International Nuclear Information System (INIS)

    Carson, W.E.; Mitchell, W. III.

    1984-02-01

    This report presents the results of an assessment of long-range research needs in nuclear waste management. The purpose is to aid the Director of Energy Research in determining the health of DOE's research programs. The intent of the project reported here was to identify additional, basic research necessary in the 1980s and 1990s to develop an adequate scientific data base for nuclear waste management activities likely to be important around the turn of the century. The recommendations resulted from an overview of the entire area of nuclear waste management, not from focused examinations of narrow topics within that area. The suggested research may be the subject of future studies or more intense work by DOE. The recommendations presented in this report are not accompanied by designations of responsible program offices within DOE. It is anticipated that the contents of the report will be shared with the program offices involved and that those offices will recognize and respond to recommendations within their purviews

  16. Structuring research methods and data with the research object model: genomics workflows as a case study.

    Science.gov (United States)

    Hettne, Kristina M; Dharuri, Harish; Zhao, Jun; Wolstencroft, Katherine; Belhajjame, Khalid; Soiland-Reyes, Stian; Mina, Eleni; Thompson, Mark; Cruickshank, Don; Verdes-Montenegro, Lourdes; Garrido, Julian; de Roure, David; Corcho, Oscar; Klyne, Graham; van Schouwen, Reinout; 't Hoen, Peter A C; Bechhofer, Sean; Goble, Carole; Roos, Marco

    2014-01-01

    One of the main challenges for biomedical research lies in the computer-assisted integrative study of large and increasingly complex combinations of data in order to understand molecular mechanisms. The preservation of the materials and methods of such computational experiments with clear annotations is essential for understanding an experiment, and this is increasingly recognized in the bioinformatics community. Our assumption is that offering means of digital, structured aggregation and annotation of the objects of an experiment will provide necessary meta-data for a scientist to understand and recreate the results of an experiment. To support this we explored a model for the semantic description of a workflow-centric Research Object (RO), where an RO is defined as a resource that aggregates other resources, e.g., datasets, software, spreadsheets, text, etc. We applied this model to a case study where we analysed human metabolite variation by workflows. We present the application of the workflow-centric RO model for our bioinformatics case study. Three workflows were produced following recently defined Best Practices for workflow design. By modelling the experiment as an RO, we were able to automatically query the experiment and answer questions such as "which particular data was input to a particular workflow to test a particular hypothesis?", and "which particular conclusions were drawn from a particular workflow?". Applying a workflow-centric RO model to aggregate and annotate the resources used in a bioinformatics experiment, allowed us to retrieve the conclusions of the experiment in the context of the driving hypothesis, the executed workflows and their input data. The RO model is an extendable reference model that can be used by other systems as well. The Research Object is available at http://www.myexperiment.org/packs/428 The Wf4Ever Research Object Model is available at http://wf4ever.github.io/ro.

  17. Do feasibility studies contribute to, or avoid, waste in research?

    Science.gov (United States)

    Morgan, Ben; Hejdenberg, Jennie; Hinrichs-Krapels, Saba; Armstrong, David

    2018-01-01

    In the context of avoiding research waste, the conduct of a feasibility study before a clinical trial should reduce the risk that further resources will be committed to a trial that is likely to 'fail'. However, there is little evidence indicating whether feasibility studies add to or reduce waste in research. Feasibility studies funded by the National Institute for Health Research's (NIHR) Research for Patient Benefit (RfPB) programme were examined to determine how many had published their findings, how many had applied for further funding for a full trial and the timeframe in which both of these occurred. A total of 120 feasibility studies which had closed by May 2016 were identified and each Principal Investigator (PI) was sent a questionnaire of which 89 responses were received and deemed suitable for analysis. Based on self reported answers from the PIs a total of 57 feasibility studies were judged as feasible, 20 were judged not feasible and for 12 it was judged as uncertain whether a full trial was feasible. The RfPB programme had spent approximately £19.5m on the 89 feasibility studies of which 16 further studies had been subsequently funded to a total of £16.8m. The 20 feasibility studies which were judged as not feasible potentially saved up to approximately £20m of further research funding which would likely to have not completed successfully. The average RfPB feasibility study took 31 months (range 18 to 48) to complete and cost £219,048 (range £72,031 to £326,830) and the average full trial funded from an RfPB feasibility study took 42 months (range 26 to 55) to complete and cost £1,163,996 (range £321,403 to £2,099,813). The average timeframe of feasibility study and full trial was 72 months (range 56 to 91), however in addition to this time an average of 10 months (range -7 to 29) was taken between the end of the feasibility study and the application for the full trial, and a further average of 18 months (range 13 to 28) between the

  18. Future studies and research in Egypt. Overview, examples, perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Goell, Edgar

    2012-02-15

    During the last decade there have been several distinct activities and efforts with regards to future research in Egypt. Several institutions and capacities have been created. Although these capacities do not always meet high scientific standards, their results and studies offer important and well-grounded elements for future-oriented discussions and political decisions. Not least because of the Egypt revolt which started in January 2011 and the ongoing complex and conflicting societal struggles in Egypt the objective needs as well as the demand for systematic future thinking and future studies will very likely increase further. For that reason this report presents an overview about the context conditions, experiences and forms of future research in Egypt. The major challenges as well as the major issues are described. The main part is the description of the most important institutions, which are conducting future research, their projects and in addition two concrete projects, which try to practice Sustainable Development in different ways. Finally, several (self-)critical assessments and perspectives from selected experts of the future research community in Egypt will be presented.

  19. Study on secondary shutdown systems in Tehran research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Jalali, H.R.; Fadaei, A.H., E-mail: Fadaei_amir@aut.ac.ir; Gharib, M.

    2015-09-15

    Highlights: • A study was undertaken to summarize the techniques for secondary shutdown systems (SSS). • Neutronic calculation performed for proposed systems as SSS. • Dumping the heavy water stored in the reflector vessel is capable to shut down reactor. • Neutronic and transient calculation was done for validating the selected SSS. • All calculation shown that this system has advantages in safety and neutron economy. - Abstract: One important safety aspect of any research reactor is the ability to shut down the reactor. Usually, research reactors, currently in operation, have a single shutdown system based on the simultaneous insertion of the all control rods into the reactor core through gravity. Nevertheless, the International Atomic Energy Agency currently recommends use of two shutdown systems which are fully independent from each other to guarantee secure shutdown when one of them fails. This work presents an investigative study into secondary shutdown systems, which will be an important safety component in the research reactor and will provide another alternative way to shut down the reactor emergently. As part of this project, a study was undertaken to summarize the techniques that are currently used at world-wide research reactors for recognizing available techniques to consider in research reactors. Removal of the reflector, removal of the fuels, change in critical shape of reactor core and insertion of neutron absorber between the core and reflector are selected as possible techniques in mentioned function. In the next step, a comparison is performed for these methods from neutronic aspects. Then, chosen method is studied from the transient behavior point of view. Tehran research reactor which is a 5 MW open-pool reactor selected as a case study and all calculations are carried out for it. It has 5 control rods which serve the purpose of both reactivity control and shutdown of reactor under abnormal condition. Results indicated that heavy

  20. Surface study of fusion research in universities linkage organization

    International Nuclear Information System (INIS)

    Miyahara, Akira.

    1980-04-01

    The surface studies for nuclear fusion research consist of the studies on the surface process and the surface damage. The problems with the surface study are different at different research stages. The plasma-wall interaction in the ignition stage is mainly concerned with heating. The impurity control becomes important in the breakeven stage. In the longer burn experiment, the problems of plasma contamination and ash accumulation are serious, and the blistering is also a problem. From the reactor aspect, the reduction of life of wall due to the irradiation of high fluence must be considered. The surface damage due to plasma disruption is a very big problem. The activities concerning the surface studies in university-linked organizations are the surface characterization for fusion reactor materials by low energy ion scattering spectroscopy, the high power ion irradiation test for CTR first wall, data compilation on plasma-wall interaction, the studies of sputtering process and surface coating, and the study on hydrogen isotope permeation through metals for fusion reactors. Other activities such as the sample characterization at many universities using the SUS 304 samples from the same lot, and the collaboration works on JIPP-T-2 plasma wall experiments are introduced. Concerning the surface study, US-Japan or international collaboration are strongly expected. (Kato, T.)

  1. Comparing Case Study and Ethnography as Qualitative Research Approaches

    OpenAIRE

    Suryani, Anne

    2008-01-01

    Abstract: This article reviews several differences between case study and ethnography in terms of definitions, characteristics, strengths and limitations. It provides current information by comparing these approaches from various social researchers’ perspectives. Although each method has strong points, they both have differences in conducting observation and interview as data collection techniques; choosing the length of time of data gathering and reporting details of a particular reality....

  2. Comparing Case Study and Ethnography as Qualitative Research Approaches

    Directory of Open Access Journals (Sweden)

    Anne Suryani

    2013-12-01

    Full Text Available Abstract: This article reviews several differences between case study and ethnography in terms of definitions, characteristics, strengths and limitations. It provides current information by comparing these approaches from various social researchers’ perspectives. Although each method has strong points, they both have differences in conducting observation and interview as data collection techniques; choosing the length of time of data gathering and reporting details of a particular reality.

  3. Study on chemical reactivity control of liquid sodium. Research program

    International Nuclear Information System (INIS)

    Saito, Jun-ichi; Ara, Kuniaki; Sugiyama, Ken-ichiro; Kitagawa, Hiroshi; Oka, Nobuki; Yoshioka, Naoki

    2007-01-01

    Liquid sodium has the excellent properties as coolant of the fast breeder reactor (FBR). On the other hand, it reacts high with water and oxygen. So an innovative technology to suppress the reactivity is desired. The purpose of this study is to control the chemical reactivity of liquid sodium by dispersing the nanometer-size metallic particles (we call them Nano-particles) into liquid sodium. We focus on the atomic interaction between Nano-particles and sodium atoms. And we try to apply it to suppress the chemical reactivity of liquid sodium. Liquid sodium dispersing Nano-particles is named 'Nano-fluid'. Research programs of this study are the Nano-particles production, the evaluation of reactivity suppression of liquid sodium and the feasibility study to FBR plant. In this paper, the research programs and status are described. The important factors for particle production were understood. In order to evaluate the chemical reactivity of Nano-fluid the research programs were planned. The feasibility of the application of Nano-fluid to the coolant of FBR plant was evaluated preliminarily from the viewpoint of design and operation. (author)

  4. Structural issues affecting mixed methods studies in health research: a qualitative study

    Science.gov (United States)

    2009-01-01

    Background Health researchers undertake studies which combine qualitative and quantitative methods. Little attention has been paid to the structural issues affecting this mixed methods approach. We explored the facilitators and barriers to undertaking mixed methods studies in health research. Methods Face-to-face semi-structured interviews with 20 researchers experienced in mixed methods research in health in the United Kingdom. Results Structural facilitators for undertaking mixed methods studies included a perception that funding bodies promoted this approach, and the multidisciplinary constituency of some university departments. Structural barriers to exploiting the potential of these studies included a lack of education and training in mixed methods research, and a lack of templates for reporting mixed methods articles in peer-reviewed journals. The 'hierarchy of evidence' relating to effectiveness studies in health care research, with the randomised controlled trial as the gold standard, appeared to pervade the health research infrastructure. Thus integration of data and findings from qualitative and quantitative components of mixed methods studies, and dissemination of integrated outputs, tended to occur through serendipity and effort, further highlighting the presence of structural constraints. Researchers are agents who may also support current structures - journal reviewers and editors, and directors of postgraduate training courses - and thus have the ability to improve the structural support for exploiting the potential of mixed methods research. Conclusion The environment for health research in the UK appears to be conducive to mixed methods research but not to exploiting the potential of this approach. Structural change, as well as change in researcher behaviour, will be necessary if researchers are to fully exploit the potential of using mixed methods research. PMID:20003210

  5. Structural issues affecting mixed methods studies in health research: a qualitative study.

    Science.gov (United States)

    O'Cathain, Alicia; Nicholl, Jon; Murphy, Elizabeth

    2009-12-09

    Health researchers undertake studies which combine qualitative and quantitative methods. Little attention has been paid to the structural issues affecting this mixed methods approach. We explored the facilitators and barriers to undertaking mixed methods studies in health research. Face-to-face semi-structured interviews with 20 researchers experienced in mixed methods research in health in the United Kingdom. Structural facilitators for undertaking mixed methods studies included a perception that funding bodies promoted this approach, and the multidisciplinary constituency of some university departments. Structural barriers to exploiting the potential of these studies included a lack of education and training in mixed methods research, and a lack of templates for reporting mixed methods articles in peer-reviewed journals. The 'hierarchy of evidence' relating to effectiveness studies in health care research, with the randomised controlled trial as the gold standard, appeared to pervade the health research infrastructure. Thus integration of data and findings from qualitative and quantitative components of mixed methods studies, and dissemination of integrated outputs, tended to occur through serendipity and effort, further highlighting the presence of structural constraints. Researchers are agents who may also support current structures - journal reviewers and editors, and directors of postgraduate training courses - and thus have the ability to improve the structural support for exploiting the potential of mixed methods research. The environment for health research in the UK appears to be conducive to mixed methods research but not to exploiting the potential of this approach. Structural change, as well as change in researcher behaviour, will be necessary if researchers are to fully exploit the potential of using mixed methods research.

  6. Research on decommissioning of nuclear facilities 2. Study on optimum scenario using the AHP (Joint research)

    International Nuclear Information System (INIS)

    Shibahara, Yuji; Morishita, Yoshitsugu; Ishigami, Tsutomu; Yanagihara, Satoshi; Arita, Yuji

    2013-01-01

    To implement a decommissioning project reasonably, it is necessary and important to calculate project management data beforehand as well as to select an optimum dismantling scenario among various scenarios postulated. Little study on the subject of selecting an optimum scenario has been carried out, and it is one of the most important issues in terms of decision making. In FY 2009, Japan Atomic Energy Agency and University of Fukui launched the joint research of a decision making method which is important to determine a decommissioning plan. The purpose of this research is to formulate a methodology for selecting an optimum dismantling scenario among various scenarios postulated based on calculated results of project management data for FUGEN. Project management data for several dismantling scenarios postulated at FUGEN were evaluated based on actual dismantling work for feedwater heater at FUGEN, and an optimum scenario was discussed using the AHP, one of Multi-Criteria Decision Analysis Methods. This report describes the results of the joint research in FY 2010. (author)

  7. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-03-02

    Mar 2, 2015 ... Joseph Daniels1,&, Ruth Nduati1,2, James Kiarie1,3, Carey Farquhar1,4,5 .... or basic science research career (Socio-Behavioral Research, .... a research environment that supports knowledge sharing to develop research ...

  8. International Conflict Studies as a Research and Teaching Area

    Directory of Open Access Journals (Sweden)

    Alexandra Viktorovna Khudaykulova

    2015-12-01

    Full Text Available The article analyzes international conflict studies as a science and an educational discipline. The analysis of the subject field and professional terminology adopted in this area both in Russian and in English is provided. Formation of international conflict studies as a distinct field of study in the United States and Western Europe is described. The results of analysis of 10 leading foreign schools on international conflict studies are presented. The main factors that were taken into account in identifying the leading centers were the existence of a separate research (educational analysis units of international conflicts, the world's leading scientific journals on conflict resolution, as well as databases for the analysis of international conflicts. The role of professional associations, education consortia and international organizations (UNESCO in the study of international conflicts is described. An analysis of the leading think tanks on defense and national security (as rated by Philadelphia think tank ranking is also provided. Particular attention is given to interdisciplinary research methodology of international conflicts and the structure of educational programs at leading schools in the world in international relations. The author summarizes the recommendations of the Association of Professional Schools of International Affairs (APSIA to create educational programs of this kind.

  9. Financial Conflicts of Interest Checklist 2010 for clinical research studies.

    Science.gov (United States)

    Rochon, Paula A; Hoey, John; Chan, An-Wen; Ferris, Lorraine E; Lexchin, Joel; Kalkar, Sunila R; Sekeres, Melanie; Wu, Wei; Van Laethem, Marleen; Gruneir, Andrea; Maskalyk, James; Streiner, David L; Gold, Jennifer; Taback, Nathan; Moher, David

    2010-01-01

    A conflict of interest is defined as "a set of conditions in which professional judgment concerning a primary interest (such as a patient's welfare or the validity of research) tends to be unduly influenced by a secondary interest (such as financial gain)" [Thompson DF. Understanding financial conflicts of interest. N Engl J Med 1993;329(8):573-576]. Because financial conflict of interest (fCOI) can occur at different stages of a study, and because it can be difficult for investigators to detect their own bias, particularly retrospectively, we sought to provide funders, journal editors and other stakeholders with a standardized tool that initiates detailed reporting of different aspects of fCOI when the study begins and continues that reporting throughout the study process to publication. We developed a checklist using a 3-phase process of pre-meeting item generation, a stakeholder meeting and post-meeting consolidation. External experts (n = 18), research team members (n = 12) and research staff members (n = 4) rated or reviewed items for some or all of the 7 major iterations. The resulting Financial Conflicts of Interest Checklist 2010 consists of 4 sections covering administrative, study, personal financial, and authorship information, which are divided into 6 modules and contain a total of 15 items and their related sub-items; it also includes a glossary of terms. The modules are designed to be completed by all investigators at different points over the course of the study, and updated information can be appended to the checklist when it is submitted to stakeholder groups for review. We invite comments and suggestions for improvement at http://www.openmedicine.ca/fcoichecklist and ask stakeholder groups to endorse the use of the checklist.

  10. Challenges in Doctoral Research Project Management: A Comparative Study

    Directory of Open Access Journals (Sweden)

    Reuven Katz

    2016-03-01

    Full Text Available This paper presents quantitative results of a comparative study evaluating the management skills of doctoral candidates working toward a PhD and additional information related to their lifestyles. We conducted a survey among enrolled doctoral candidates at five universities in Israel and three technological universities in Western Europe. 1013 Israeli candidates and 457 Western European candidates replied to our survey. In our analysis, we compared the answers of Israeli Science and Engineering candidates to those of Social Sciences and Humanities candidates; in addition, we compared the answers of Israeli Science and Engineering students to their Western European peers. Our analysis focused on finding significant patterns by comparing these groups of students. In order to identify such patterns, we analyzed each question using the Pearson chi-square test. The current study’s main finding is that the majority of candidates, regardless of their chosen academic field or the region where they study, have no training or expertise in managing a doctoral research project. Based on these findings, we suggest that all doctoral candidates be taught basic research-project management. We believe that such training will provide them with a powerful tool for better managing their research as they advance towards successful completion of their doctorate.

  11. Uses of Published Research: An Exploratory Case Study

    Directory of Open Access Journals (Sweden)

    Patrick J. Fahy

    Full Text Available Academic publications are too often ignored by other researchers. There are various reasons: Researchers know that conclusions may eventually be proved wrong; publications are sometimes retracted; effects may decline when studied later; researchers occasionally don’t seem to know about papers they have allegedly authored; there are even accusations of fraud (Cohen, 2011. In this exploratory case study, 10 papers were examined to determine the various ways they were used by others, whether there were cases of reported effects declining, and whether, among those who referenced the papers, there were suggestions that anything in the papers ought to be retracted. Findings showed that all the papers had been referenced by others (337 user publications were found, containing a total of 868 references. Other findings include the following: Single references were far more common than multiple references; applications/replications were the least common type of usage (23 occurrences, followed by contrasts/elaborations (34, and quotations (65; unlike reports regarding publications in the sciences, whether the paper was solo- or co-authored did not affect usage; appearance in a non-prestige journal was actually associated with more usage of some kinds; and well over 80% of uses were in heavily scrutinized sources (journal articles or theses/dissertations. The paper concludes with recommendations to writers about how to avoid producing publications that are ignored.

  12. Review of studies of research opportunities in energy conservation

    Energy Technology Data Exchange (ETDEWEB)

    Hane, G.J.; Williams, T.A.; Hauser, S.G.

    1984-04-01

    This study attempted to systematically identify, screen and review many of the 27 remaining major studies across the end-use areas. The method used to identify and review the studies, the scope of this effort, the types of studies reviewed, and the R and D opportunities identified are discussed. The actual report reviews are included. The review format and the kinds of information sought from each report are discussed. The general categories of the material are described; the types of information presented are summarized; and gaps in the literature are discussed. A discussion of R and D needs and comments of the specific needs presented and their temporal and evolutionary characteristics are included. The findings of the review are summarized and the researchers contacted for information are listed.

  13. A Study of How We Study: Methodologies of School Library Research 2007 through July 2015

    Science.gov (United States)

    Morris, Rebecca J.; Cahill, Maria

    2017-01-01

    In this study we investigated the research designs employed to study the interdisciplinary profession of school librarianship during a time period of notable changes across both the Pre-K-12 and school library domains. To conduct this work, we analyzed all 217 articles published in "School Library Research" (SLR) and "School…

  14. Research lessons from implementing a national nursing workforce study.

    Science.gov (United States)

    Brzostek, T; Brzyski, P; Kózka, M; Squires, A; Przewoźniak, L; Cisek, M; Gajda, K; Gabryś, T; Ogarek, M

    2015-09-01

    National nursing workforce studies are important for evidence-based policymaking to improve nursing human resources globally. Survey instrument translation and contextual adaptation along with level of experience of the research team are key factors that will influence study implementation and results in countries new to health workforce studies. This study's aim was to describe the pre-data collection instrument adaptation challenges when designing the first national nursing workforce study in Poland while participating in the Nurse Forecasting: Human Resources Planning in Nursing project. A descriptive analysis of the pre-data collection phase of the study. Instrument adaptation was conducted through a two-phase content validity indexing process and pilot testing from 2009 to September 2010 in preparation for primary study implementation in December 2010. Means of both content validation phases were compared with pilot study results to assess for significant patterns in the data. The initial review demonstrated that the instrument had poor level of cross-cultural relevance and multiple translation issues. After revising the translation and re-evaluating using the same process, instrument scores improved significantly. Pilot study results showed floor and ceiling effects on relevance score correlations in each phase of the study. The cross-cultural adaptation process was developed specifically for this study and is, therefore, new. It may require additional replication to further enhance the method. The approach used by the Polish team helped identify potential problems early in the study. The critical step improved the rigour of the results and improved comparability for between countries analyses, conserving both money and resources. This approach is advised for cross-cultural adaptation of instruments to be used in national nursing workforce studies. Countries seeking to conduct national nursing workforce surveys to improve nursing human resources policies may

  15. Study on applicability of low alkaline cement in Horonobe Underground Research Laboratory project (2) (Contract research)

    International Nuclear Information System (INIS)

    Nakayama, Masashi; Kobayashi, Yasushi; Matsuda, Takeshi; Noda, Masaru; Iriya, Keishiro; Takeda, Nobufumi

    2009-11-01

    In Horonobe Underground Research Center construction of underground facility began in 2005 and a construction practicality test with HFSC (Highly Fly-ash contained Silica-fume Cement) is planned in a part of the gallery. Before the HFSC is used as a tunnel support in the gallery, it is necessary to validate that the HFSC is valid under the actual construction condition. The research results in the FY 2007 are as follows. For evaluating corrosion behavior in the HFSC and the durability of the HFSC, reinforced concrete specimen with HFSC 226 have been exposed to off-shore condition in saline water and splashed zone for 6 years and analyzed the corrosion rate and the amount of chloride intrusion. The durability of the HFSC reinforced concrete was assessed to be more than 50 years until cracking due to corrosion is generated. The pH measurements and the analysis of the chemical composition of solid and liquid phase in the HFSC cocrete-water immersion experiments, which were started in the FY 2002, were carried out. Also for the experiments of cement paste for shotcreting, which were started in the FY 2005, were analyzed. Furthermore, results and findings obtained in earlier studies including this study were summarized, and based on those, method of quality control including test method, frequency, standards etc. was suggested. (author)

  16. Action Researchers' Perspectives about the Distinguishing Characteristics of Action Research: A Delphi and Learning Circles Mixed-Methods Study

    Science.gov (United States)

    Rowell, Lonnie L.; Polush, Elena Yu; Riel, Margaret; Bruewer, Aaron

    2015-01-01

    The purpose of this study was to identify distinguishing characteristics of action research within the Action Research Special Interest Group of the American Educational Research Association. The authors sought to delineate the foundational framework endorsed by this community. The study was conducted during January-April 2012 and employed an…

  17. Yale High Energy Physics Research: Precision Studies of Reactor Antineutrinos

    Energy Technology Data Exchange (ETDEWEB)

    Heeger, Karsten M. [Yale Univ., New Haven, CT (United States)

    2014-09-13

    This report presents experimental research at the intensity frontier of particle physics with particular focus on the study of reactor antineutrinos and the precision measurement of neutrino oscillations. The experimental neutrino physics group of Professor Heeger and Senior Scientist Band at Yale University has had leading responsibilities in the construction and operation of the Daya Bay Reactor Antineutrino Experiment and made critical contributions to the discovery of non-zero$\\theta_{13}$. Heeger and Band led the Daya Bay detector management team and are now overseeing the operations of the antineutrino detectors. Postdoctoral researchers and students in this group have made leading contributions to the Daya Bay analysis including the prediction of the reactor antineutrino flux and spectrum, the analysis of the oscillation signal, and the precision determination of the target mass yielding unprecedented precision in the relative detector uncertainty. Heeger's group is now leading an R\\&D effort towards a short-baseline oscillation experiment, called PROSPECT, at a US research reactor and the development of antineutrino detectors with advanced background discrimination.

  18. Yale High Energy Physics Research: Precision Studies of Reactor Antineutrinos

    International Nuclear Information System (INIS)

    Heeger, Karsten M.

    2014-01-01

    This report presents experimental research at the intensity frontier of particle physics with particular focus on the study of reactor antineutrinos and the precision measurement of neutrino oscillations. The experimental neutrino physics group of Professor Heeger and Senior Scientist Band at Yale University has had leading responsibilities in the construction and operation of the Daya Bay Reactor Antineutrino Experiment and made critical contributions to the discovery of non-zero$\\theta . Heeger and Band led the Daya Bay detector management team and are now overseeing the operations of the antineutrino detectors. Postdoctoral researchers and students in this group have made leading contributions to the Daya Bay analysis including the prediction of the reactor antineutrino flux and spectrum, the analysis of the oscillation signal, and the precision determination of the target mass yielding unprecedented precision in the relative detector uncertainty. Heeger's group is now leading an R\\&D effort towards a short-baseline oscillation experiment, called PROSPECT, at a US research reactor and the development of antineutrino detectors with advanced background discrimination.

  19. Identification of a research protocol to study orthodontic tooth movement

    Directory of Open Access Journals (Sweden)

    Annalisa Dichicco

    2014-06-01

    Full Text Available Aim: The orthodontic movement is associated with a process of tissue remodeling together with the release of several chemical mediators in periodontal tissues. Each mediator is a potential marker of tooth movement and expresses biological processes as: tissue inflammation and bone remodeling. Different amounts of every mediator are present in several tissues and fluids of the oral cavity. Therefore, there are different methods that allow sampling with several degrees of invasiveness. Chemical mediators are also substances of different molecular nature, and multiple kind of analysis methods allow detection. The purpose of this study was to draft the best research protocol for an optimal study on orthodontic movement efficiency. Methods: An analysis of the international literature have been made, to identify the gold standard of each aspect of the protocol: type of mediator, source and method of sampling and analysis method. Results: From the analysis of the international literature was created an original research protocol for the study and the assessment of the orthodontic movement, by using the biomarkers of the tooth movement. Conclusions: The protocol created is based on the choice of the gold standard of every aspect already analyzed in the literature and in existing protocols for the monitoring of orthodontic tooth movement through the markers of tooth movement. Clinical trials re required for the evaluation and validation of the protocol created.

  20. Research

    African Journals Online (AJOL)

    A descriptive qualitative research design was used to determine whether participants ... simulation as a teaching method; a manikin offering effective learning; confidence ..... Tesch R. Qualitative Research: Analysis Types and Software Tools.

  1. Culture Studies in the Field of International Business Research

    DEFF Research Database (Denmark)

    Worm, Verner; Li, Xin; Jakobsen, Michael

    Purpose: The purpose of this paper is to describe the status of culture studies within the field of international business research, and to examine how two main paradigms – essentialism and social constructivism – relate to the discourse in this field. We analyze the main points of the two...... in this paper. Practical implications: We encourage practitioners to learn how to switch, both sequentially and spatially, between the two paradigms of culture (fundamentally incommensurable though they are). This involves taking a “both/or” approach to the two paradigms. Originality/Value: We show...

  2. An alternative approach for socio-hydrology: case study research

    Science.gov (United States)

    Mostert, Erik

    2018-01-01

    Currently the most popular approach in socio hydrology is to develop coupled human-water models. This article proposes an alternative approach, qualitative case study research, involving a systematic review of (1) the human activities affecting the hydrology in the case, (2) the main human actors, and (3) the main factors influencing the actors and their activities. Moreover, this article presents a case study of the Dommel Basin in Belgium and the Netherlands, and compares this with a coupled model of the Kissimmee Basin in Florida. In both basins a pendulum swing from water resources development and control to protection and restoration can be observed. The Dommel case study moreover points to the importance of institutional and financial arrangements, community values, and broader social, economic, and technical developments. These factors are missing from the Kissimmee model. Generally, case studies can result in a more complete understanding of individual cases than coupled models, and if the cases are selected carefully and compared with previous studies, it is possible to generalize on the basis of them. Case studies also offer more levers for management and facilitate interdisciplinary cooperation. Coupled models, on the other hand, can be used to generate possible explanations of past developments and quantitative scenarios for future developments. The article concludes that, given the limited attention they currently get and their potential benefits, case studies deserve more attention in socio-hydrology.

  3. FIRE (facilitating implementation of research evidence: a study protocol

    Directory of Open Access Journals (Sweden)

    Seers Kate

    2012-03-01

    Full Text Available Abstract Background Research evidence underpins best practice, but is not always used in healthcare. The Promoting Action on Research Implementation in Health Services (PARIHS framework suggests that the nature of evidence, the context in which it is used, and whether those trying to use evidence are helped (or facilitated affect the use of evidence. Urinary incontinence has a major effect on quality of life of older people, has a high prevalence, and is a key priority within European health and social care policy. Improving continence care has the potential to improve the quality of life for older people and reduce the costs associated with providing incontinence aids. Objectives This study aims to advance understanding about the contribution facilitation can make to implementing research findings into practice via: extending current knowledge of facilitation as a process for translating research evidence into practice; evaluating the feasibility, effectiveness, and cost-effectiveness of two different models of facilitation in promoting the uptake of research evidence on continence management; assessing the impact of contextual factors on the processes and outcomes of implementation; and implementing a pro-active knowledge transfer and dissemination strategy to diffuse study findings to a wide policy and practice community. Setting and sample Four European countries, each with six long-term nursing care sites (total 24 sites for people aged 60 years and over with documented urinary incontinence Methods and design Pragmatic randomised controlled trial with three arms (standard dissemination and two different programmes of facilitation, with embedded process and economic evaluation. The primary outcome is compliance with the continence recommendations. Secondary outcomes include proportion of residents with incontinence, incidence of incontinence-related dermatitis, urinary tract infections, and quality of life. Outcomes are assessed at baseline

  4. Managing Astronomy Research Data: Case Studies of Big and Small Research Projects

    Science.gov (United States)

    Sands, Ashley E.

    2015-01-01

    Astronomy data management refers to all actions taken upon data over the course of the entire research process. It includes activities involving the collection, organization, analysis, release, storage, archiving, preservation, and curation of research data. Astronomers have cultivated data management tools, infrastructures, and local practices to ensure the use and future reuse of their data. However, new sky surveys will soon amass petabytes of data requiring new data management strategies.The goal of this dissertation, to be completed in 2015, is to identify and understand data management practices and the infrastructure and expertise required to support best practices. This will benefit the astronomy community in efforts toward an integrated scholarly communication framework.This dissertation employs qualitative, social science research methods (including interviews, observations, and document analysis) to conduct case studies of data management practices, covering the entire data lifecycle, amongst three populations: Sloan Digital Sky Survey (SDSS) collaboration team members; Individual and small-group users of SDSS data; and Large Synoptic Survey Telescope (LSST) collaboration team members. I have been observing the collection, release, and archiving of data by the SDSS collaboration, the data practices of individuals and small groups using SDSS data in journal articles, and the LSST collaboration's planning and building of infrastructure to produce data.Preliminary results demonstrate that current data management practices in astronomy are complex, situational, and heterogeneous. Astronomers often have different management repertoires for working on sky surveys and for their own data collections, varying their data practices as they move between projects. The multitude of practices complicates coordinated efforts to maintain data.While astronomy expertise proves critical to managing astronomy data in the short, medium, and long term, the larger astronomy

  5. Research

    African Journals Online (AJOL)

    research process, as part of which students must find and appraise evidence from research.[5] This highlights that teaching research methodology is inclined towards equipping students ... Students believed that evidence-based practice was vital, yet their understanding of the concept was restricted when compared with the.

  6. Patient engagement with research: European population register study.

    Science.gov (United States)

    McKevitt, Christopher; Fudge, Nina; Crichton, Siobhan; Bejot, Yannick; Daubail, Benoît; Di Carlo, Antonio; Fearon, Patricia; Kolominsky-Rabas, Peter; Sheldenkar, Anita; Newbound, Sophie; Wolfe, Charles D A

    2015-12-01

    Lay involvement in implementation of research evidence into practice may include using research findings to guide individual care, as well as involvement in research processes and policy development. Little is known about the conditions required for such involvement. To assess stroke survivors' research awareness, use of research evidence in their own care and readiness to be involved in research processes. Cross sectional survey of stroke survivors participating in population-based stroke registers in six European centres. The response rate was 74% (481/647). Reasons for participation in register research included responding to clinician request (56%) and to 'give something back' (19%); however, 20% were unaware that they were participating in a stroke register. Research awareness was generally low: 57% did not know the purpose of the register they had been recruited to; 73% reported not having received results from the register they took part in; 60% did not know about any research on stroke care. Few participants (7.6%) used research evidence during their consultations with a doctor. The 34% of participants who were interested in being involved in research were younger, more highly educated and already research aware. Across Europe, stroke survivors already participating in research appear ill informed about stroke research. Researchers, healthcare professionals and patient associations need to improve how research results are communicated to patient populations and research participants, and to raise awareness of the relationship between research evidence and increased quality of care. © 2014 John Wiley & Sons Ltd.

  7. [Application and Integration of Qualitative and Quantitative Research Methods in Intervention Studies in Rehabilitation Research].

    Science.gov (United States)

    Wirtz, M A; Strohmer, J

    2016-06-01

    In order to develop and evaluate interventions in rehabilitation research a wide range of empirical research methods may be adopted. Qualitative research methods emphasize the relevance of an open research focus and a natural proximity to research objects. Accordingly, using qualitative methods special benefits may arise if researchers strive to identify and organize unknown information aspects (inductive purpose). Particularly, quantitative research methods require a high degree of standardization and transparency of the research process. Furthermore, a clear definition of efficacy and effectiveness exists (deductive purpose). These paradigmatic approaches are characterized by almost opposite key characteristics, application standards, purposes and quality criteria. Hence, specific aspects have to be regarded if researchers aim to select or combine those approaches in order to ensure an optimal gain in knowledge. © Georg Thieme Verlag KG Stuttgart · New York.

  8. State policy and teen childbearing: a review of research studies.

    Science.gov (United States)

    Beltz, Martha A; Sacks, Vanessa H; Moore, Kristin A; Terzian, Mary

    2015-02-01

    Teen childbearing is affected by many individual, family, and community factors; however, another potential influence is state policy. Rigorous studies of the relationship between state policy and teen birth rates are few in number but represent a body of knowledge that can inform policy and practice. This article reviews research assessing associations between state-level policies and teen birth rates, focusing on five policy areas: access to family planning, education, sex education, public assistance, and access to abortion services. Overall, several studies have found that measures related to access to and use of family planning services and contraceptives are related to lower state-level teen birth rates. These include adolescent enrollment in clinics, minors' access to contraception, conscience laws, family planning expenditures, and Medicaid waivers. Other studies, although largely cross-sectional analyses, have concluded that policies and practices to expand or improve public education are also associated with lower teen birth rates. These include expenditures on education, teacher-to-student ratios, and graduation requirements. However, the evidence regarding the role of public assistance, abortion access, and sex education policies in reducing teen birth rates is mixed and inconclusive. These conclusions must be viewed as tentative because of the limited number of rigorous studies that examine the relationship between state policy and teen birth rates over time. Many specific policies have only been analyzed by a single study, and few findings are based on recent data. As such, more research is needed to strengthen our understanding of the role of state policies in teen birth rates. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  9. Medical researchers unite for study on cancer intervention

    Directory of Open Access Journals (Sweden)

    Editorial Office

    2016-08-01

    the areas of molecular biology, cell biology, and cancer research.Some of the awards received by Dr. Snijders include the prestigious President’s Award for Excellence and the Student Travel Award at the 2014’s XXII International Congress of the International Society for Analytical Cytology in Montpellier, France. He was also the co-recipient of the AACR Team Science Award for the conception, technical implementation, dissemination, and pioneering applications of an array comparative genomic hybridization technique from the American Association of Cancer Research in 2008. Meanwhile, Dr. Mao studied applied mathematics at Southeast University, Nanjing, China, and pursued his masters in biostatistics and cancer epidemiology at Beijing Medical University (now Peking University Health Science Center. In 1988, Dr. Mao received the Outstanding Postgraduate Award from Beijing Medical University and two years later, was awarded an Outstanding Lecturer Award from the same university. He then pursued his PhD in cancer genetics at the Department of Radiation Oncology, University of Glasgow, UK. During this period, Dr. Mao was awarded the Oversea Research Student Awards from the Committee of Vice-Chancellor and Principals of the Universities of the United Kingdom, along with the Glasgow University Travel fellowship.Dr. Snijders and Dr. Mao joined Berkeley Lab in 2008 as resident scientist and genetic staff scientist, respectively, where their work focuses on using the multi-omics approach to identify critical genes as potential therapeutic targets and prognostic biomarkers. “At the same time, we investigate underlying biological mechanisms and functions using different model systems, including genetically engineered mouse models,” they told AMOR.“Mouse models offer many advantages for the study of the genetic basis of complex traits, including radiation-induced cancers, because of our ability to control both the genetic and environmental components of risk. The goal is

  10. PROFESSIONAL CONTENTMENT IN A RESEARCH UNIVERSITY:A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Hamidah Abdul Rahman

    2011-01-01

    Full Text Available There have been many studies conducted to determine variables that affect professional contentment. Some of these studies hav e looked at factors such as organizational involvement and commitment to organi zations. Several of these studies found that a larger percentage of unemploye d and employed personnel expressed dissatisfaction with their work commitmen t. The implications of those studies suggested that unemployed could reflect und erlying adjustment disorders which have an impact on someone’s potential for suc cessful employment. However, for those who are contented with their per formance, in the long run these workers would have a higher gratification. Th ey would give more attention on the quality of their work, more committed to the organization, have a higher retention rates, and would be more productive. Refl ecting on these findings and how severe this issue may render, this study is con ducted to identify the level of professional satisfaction of the academic staffs in a research university in the southern part of Malaysia. This paper will present the findings of the study which aimed to determine the level of satisfaction based on factors such as pay, promotion, supervision, fringe benefit, contingent eward, operating condition, coworkers, nature of work and communication

  11. Research studies performed using the Cairo Fourier Diffractometer Facility

    International Nuclear Information System (INIS)

    Maayouf, R.M.A.; Ridikas, D.

    2009-12-01

    This report represents the results of the research studies performed using the Cairo Fourier Diffractometer Facility (CFDF), within 10 years after it was installed and put into operation at the beginning of 1996. The main components of the CFDF were supplied by the IAEA according to the technical assistance project EGY/1/022 'Upgrading of Research Reactor Utilization'. The present report is the second published INDC report, while the first one, published at the beginning of 1997, was about the performance of the CFDF and its main characteristic parameters. Plenty of measurements were performed since then, yielding several publications both in local and international scientific periodicals and resulting in 8 M.Sc. and Ph.D. degrees from Egyptian Universities. In addition, a new approach for the analysis of the neutron spectra was implemented using the CFDF. Specially designed interface card with proper software program was applied instead of the reverse time of flight (RTOF) and Finnish made analyzer originally attached to the facility. It has been verified that the new approach can successfully replace the RTOF analyzer, significantly decreasing the time of measurement and saving the reactor's operation time. Besides, a special fault diagnostic system program was developed and tested for caring and handling the possible failures of the CFDF. Moreover, measurements were carried out for the diffraction spectra emitted at different points of one of the samples. The latter was scanned across the neutron beam of the CFDF, for studying the stress after welding; used in industrial applications. (author)

  12. A systems medicine research approach for studying alcohol addiction.

    Science.gov (United States)

    Spanagel, Rainer; Durstewitz, Daniel; Hansson, Anita; Heinz, Andreas; Kiefer, Falk; Köhr, Georg; Matthäus, Franziska; Nöthen, Markus M; Noori, Hamid R; Obermayer, Klaus; Rietschel, Marcella; Schloss, Patrick; Scholz, Henrike; Schumann, Gunter; Smolka, Michael; Sommer, Wolfgang; Vengeliene, Valentina; Walter, Henrik; Wurst, Wolfgang; Zimmermann, Uli S; Stringer, Sven; Smits, Yannick; Derks, Eske M

    2013-11-01

    According to the World Health Organization, about 2 billion people drink alcohol. Excessive alcohol consumption can result in alcohol addiction, which is one of the most prevalent neuropsychiatric diseases afflicting our society today. Prevention and intervention of alcohol binging in adolescents and treatment of alcoholism are major unmet challenges affecting our health-care system and society alike. Our newly formed German SysMedAlcoholism consortium is using a new systems medicine approach and intends (1) to define individual neurobehavioral risk profiles in adolescents that are predictive of alcohol use disorders later in life and (2) to identify new pharmacological targets and molecules for the treatment of alcoholism. To achieve these goals, we will use omics-information from epigenomics, genetics transcriptomics, neurodynamics, global neurochemical connectomes and neuroimaging (IMAGEN; Schumann et al. ) to feed mathematical prediction modules provided by two Bernstein Centers for Computational Neurosciences (Berlin and Heidelberg/Mannheim), the results of which will subsequently be functionally validated in independent clinical samples and appropriate animal models. This approach will lead to new early intervention strategies and identify innovative molecules for relapse prevention that will be tested in experimental human studies. This research program will ultimately help in consolidating addiction research clusters in Germany that can effectively conduct large clinical trials, implement early intervention strategies and impact political and healthcare decision makers. © 2013 Society for the Study of Addiction.

  13. Feasibility study for Tehran Research Reactor power upgrading

    Energy Technology Data Exchange (ETDEWEB)

    Farhadi, Kazem [Nuclear Research Center, Atomic Energy Organization of Iran (AEOI), Tehran (Iran, Islamic Republic of)], E-mail: kfarhadi@aeoi.org.ir; Khakshournia, Samad [Nuclear Research Center, Atomic Energy Organization of Iran (AEOI), Tehran (Iran, Islamic Republic of)

    2008-07-15

    The present work is concerned with a power upgrading study of Tehran Research Reactor (TRR). The upgrading study is aimed at investigating the possibility of raising power of the TRR from the current level of 5 MW{sub th} to a higher level without violating the original thermal-hydraulic safety criteria. The existing core, comprising 22 standard fuel elements and five control fuel elements, is used for the analyses. Different reactor thermal powers (5-11 MW) and different core coolant flow rates (500-921 m{sup 3}/h) are considered. It is shown that, for the present core, this goal could be achieved safely by gradually opening the butterfly control valve until the desired coolant flow rate is reached. The TRR power could be upgraded up to around 7.5 MW{sub th} with the total power peaking factor maintained at less than or equal to 3.0.

  14. Application of CFD to a generic hypersonic flight research study

    Science.gov (United States)

    Green, Michael J.; Lawrence, Scott L.; Dilley, Arthur D.; Hawkins, Richard W.; Walker, Mary M.; Oberkampf, William L.

    1993-01-01

    Computational analyses have been performed for the initial assessment of flight research vehicle concepts that satisfy requirements for potential hypersonic experiments. Results were obtained from independent analyses at NASA Ames, NASA Langley, and Sandia National Labs, using sophisticated time-dependent Navier-Stokes and parabolized Navier-Stokes methods. Careful study of a common problem consisting of hypersonic flow past a slightly blunted conical forebody was undertaken to estimate the level of uncertainty in the computed results, and to assess the capabilities of current computational methods for predicting boundary-layer transition onset. Results of this study in terms of surface pressure and heat transfer comparisons, as well as comparisons of boundary-layer edge quantities and flow-field profiles are presented here. Sensitivities to grid and gas model are discussed. Finally, representative results are presented relating to the use of Computational Fluid Dynamics in the vehicle design and the integration/support of potential experiments.

  15. Feasibility study for Tehran Research Reactor power upgrading

    International Nuclear Information System (INIS)

    Farhadi, Kazem; Khakshournia, Samad

    2008-01-01

    The present work is concerned with a power upgrading study of Tehran Research Reactor (TRR). The upgrading study is aimed at investigating the possibility of raising power of the TRR from the current level of 5 MW th to a higher level without violating the original thermal-hydraulic safety criteria. The existing core, comprising 22 standard fuel elements and five control fuel elements, is used for the analyses. Different reactor thermal powers (5-11 MW) and different core coolant flow rates (500-921 m 3 /h) are considered. It is shown that, for the present core, this goal could be achieved safely by gradually opening the butterfly control valve until the desired coolant flow rate is reached. The TRR power could be upgraded up to around 7.5 MW th with the total power peaking factor maintained at less than or equal to 3.0

  16. CD3+/CD8+ T-cell density and tumoral PD-L1 predict survival irrespective of rituximab treatment in Chinese diffuse large B-cell lymphoma patients.

    Science.gov (United States)

    Shi, Yunfei; Deng, Lijuan; Song, Yuqin; Lin, Dongmei; Lai, Yumei; Zhou, LiXin; Yang, Lei; Li, Xianghong

    2018-05-10

    To investigate the prognostic value of tumor-infiltrating T-cell density and programmed cell death ligand-1 (PD-L1) expression in diffuse large B cell lymphoma (DLBCL). One-hundred-twenty-five Chinese DLBCL patients were enrolled in our study and provided samples; 76 of all cases were treated with rituximab (R). Tumor tissues were immunostained and analyzed for CD3+ and CD8+ tumor-infiltrating T-cell density, tumoral PD-L1, and microenvironmental PD-L1 (mPD-L1). The density of CD3 was rated as high in 33.6% cases, while 64.0% of DLBCLs were classified as high CD8 density. Of all cases, 16.8% were PD-L1+. Of the remaining PD-L1-DLBCLs, 29.8% positively expressed mPD-L1. Both CD3 high density and CD8 high density were associated with mPD-L1 positivity (P = 0.001 and P = 0.0001). In multivariate analysis, independently, high CD3 density predicted better OS (P = 0.023), while CD8 high density and PD-L1 positivity were both associated with prolonged PFS (P = 0.013 and P = 0.036, respectively). Even in the subgroup treated with R, univariate analyses indicated that high CD3 density and PD-L1 positivity were associated with better OS (P = 0.041) and PFS (P = 0.033), respectively. The infiltrating densities of CD3+ T-cells, CD8+ T-cells, and PD-L1 expression are predictive of survival in DLBCLs, irrespective of R usage.

  17. A Study on the Spatial Abilities of Prospective Social Studies Teachers: A Mixed Method Research

    Science.gov (United States)

    Yurt, Eyüp; Tünkler, Vural

    2016-01-01

    This study investigated prospective social studies teachers' spatial abilities. It was conducted with 234 prospective teachers attending Social Studies Teaching departments at Education Faculties of two universities in Central and Southern Anatolia. This study, designed according to the explanatory-sequential design, is a mixed research method,…

  18. Chinese TEFL Academics' Perceptions about Research: An Institutional Case Study

    Science.gov (United States)

    Bai, Li; Millwater, Jan

    2011-01-01

    Research capacity building has become a prominent theme in higher education institutions in China, as across the world. However, Chinese TEFL (Teaching English as a Foreign Language) academics' research capacity has been quite limited. In order to build their research capacity, it is necessary to understand their perceptions about research. This…

  19. World Regional Studies as a Research Framework and Academic Discipline

    Directory of Open Access Journals (Sweden)

    Ekaterina V. Koldunova

    2016-01-01

    Full Text Available Dynamic development of international processes at the regional level, various trajectories of regionalization in Europe, Asia, Latin America and other parts of the world created a complex and multidimensional picture of the contemporary international relations. However Social Sciences and IR retained a distinct eurocentrism. This eurocentrism only partly meant that students of IR did not take into account non-European or non-Western realities. Thus, a German Scholar J. Vullers from German Institute of Global and Area Studies analyzing in 2014 three leading International Relations journals (International Organization, World Politics, European Journal of International Relations diagnosed a serious geographic imbalance in the international studies, which meant a very limited number of articles based on the nonWestern empirical data.Even with such geographic imbalance in IR studies more important for preserving eurocentrism there was the absence of non-Western IR theories or IR theories originating from non-Western political context. The collective monograph edited by Barry Buzan and Amitav Acharya focused exactly on this problem. The title of the book was provocatively asking why there is no non-Western IR theory. Thus, the book in question provoked a lively academic debate on the topic. Russia was not covered in this book. Therefore, this very fact gives one some reasons to reflect on how Russian research in the field may face a double challenge of a changing international environment and an inappropriate level of its intellectual assessment. Against this background this article analyzes World Regional Studies, a research framework and discipline, which is rapidly developing in Russia and may to some extent contribute to a more correct understanding of the international processes.

  20. Studies in Teaching 1999 Research Digest. Research Projects Presented at Annual Research Forum (Winston-Salem, North Carolina, December 1999).

    Science.gov (United States)

    McCoy, Leah P., Ed.

    This publication presents a collection of research projects presented at the Annual Research Forum at Wake Forest University: "The Use of Group Work as an Effective Teaching Technique in Lower Level Spanish Classes" (James Blackburn); "What Are the Real Factors behind Student Motivation?" (Matthew Grey Burdick); "Can…

  1. Study on Related Courses to Help Undergraduate Students Write Research Reports: a Curriculum Evaluation

    OpenAIRE

    Winarti, Eny

    2014-01-01

    From the experience of joining the boards in the students’ research report defence, teaching education research methodology, and classroom action research, the researcher indicated that students had challenges related with the logic of research methods and academic research writing.  These findings encouraged the researcher to study the courses that have potential in helping students writing their research reports.  To study the courses, the researcher analysed related documents, such as ...

  2. SCI Longitudinal Aging Study: 40 Years of Research.

    Science.gov (United States)

    Krause, James S; Clark, Jillian M R; Saunders, Lee L

    2015-01-01

    The Spinal Cord Injury (SCI) Longitudinal Aging Study was initiated in 1973 and has conducted 8 assessments over the past 40 years. It was designed to help rehabilitation professionals understand the life situation of people with SCI, but it has developed into the most long-standing study of aging and SCI and has resulted in over 50 publications. Our purpose was to provide a detailed history of the study, response patterns, utilization of measures, and a summary of key findings reported in the literature. Five participant samples have been incorporated over the 40 years, with enrollment in 1973, 1984, 1993 (2 samples), and 2003. A total of 2,208 participants have completed 6,001 assessments, with a particularly large number of assessments among those who are more than 40 years post injury (n = 349). The overall results have indicated changing patterns of outcomes over time as persons with SCI age, with some notable declines in participation and health. There has been a survivor effect whereby persons who are more active, well-adjusted, and healthier live longer. This study has several important features that are required for longitudinal research including (a) consistency of follow-up, (b) consistency of measures over time, (c) addition of new participant samples to counteract attrition, and (d) inclusion of a large number of individuals who have reached aging milestones unparalleled in the literature. Data from this study can inform the literature on the natural course of aging with SCI.

  3. Advance directives in dementia research: The opinions and arguments of clinical researchers − an empirical study

    NARCIS (Netherlands)

    K.R. Jongsma (Karin); S. van de Vathorst (Suzanne)

    2015-01-01

    textabstractIn order to discover an effective treatment for dementia it is necessary to include dementia patients in clinical research trials. Dementia patients face an increased risk to lose the capacity to consent to research participation, and research possibilities with incompetent participants

  4. Estimating study costs for use in VOI, a study of dutch publicly funded drug related research

    NARCIS (Netherlands)

    Van Asselt, A.D.; Ramaekers, B.L.; Corro Ramos, I.; Joore, M.A.; Al, M.J.; Lesman-Leegte, I.; Postma, M.J.; Vemer, P.; Feenstra, T.F.

    2016-01-01

    Objectives: To perform value of information (VOI) analyses, an estimate of research costs is needed. However, reference values for such costs are not available. This study aimed to analyze empirical data on research budgets and, by means of a cost tool, provide an overview of costs of several types

  5. Occupational health research priorities in Malaysia: a Delphi study.

    Science.gov (United States)

    Sadhra, S; Beach, J R; Aw, T C; Sheikh-Ahmed, K

    2001-07-01

    As part of a consultancy project on occupational health, the Delphi method was used to identify research priorities in occupational health in Malaysia. Participation was sought from government ministries, industry, and professional organisations, and university departments with an interest in occupational and public health. Two rounds of questionnaires resulted in a final list of priorities, with noticeable differences between participants depending on whether they worked in industry or were from government organisations. The participation rate of 71% (55 of 78) was obtained for the first questionnaire and 76% (72 of 95) for the second questionnaire. The participants identified occupational health problems for specific groups and industries as the top research priority area (ranked as top priority by 25% of participants). Ministry of Health participants placed emphasis on healthcare workers (52% ranking it as top priority), whereas those from industry identified construction and plantation workers as groups, which should be accorded the highest priority. Evaluation of research and services was given a low priority. The priorities for occupational health determined with the Delphi approach showed differences between Malaysia, a developing country, and findings from similar European studies. This may be expected, as differences exist in stages of economic development, types of industries, occupational activities, and cultural attitudes to occupational health and safety. Chemical poisonings and workplace accidents were accorded a high priority. By contrast with findings from western countries, workplace psychosocial problems and musculoskeletal injuries were deemed less important. There also seemed to be greater emphasis on adopting interventions for identified problems based on experience in other countries rather than the need to evaluate local occupational health provisions.

  6. UAS as a Support for Atmospheric Aerosols Research: Case Study

    Science.gov (United States)

    Chiliński, Michał T.; Markowicz, Krzysztof M.; Kubicki, Marek

    2018-01-01

    Small drones (multi-copters) have the potential to deliver valuable data for atmospheric research. They are especially useful for collecting vertical profiles of optical and microphysical properties of atmospheric aerosols. Miniaturization of sensors, such as aethalometers and particle counters, allows for collecting profiles of black carbon concentration, absorption coefficient, and particle size distribution. Vertical variability of single-scattering properties has a significant impact on radiative transfer and Earth's climate, but the base of global measurements is very limited. This results in high uncertainties of climate/radiation models. Vertical range of modern multi-copters is up to 2000 m, which is usually enough to study aerosols up to the top of planetary boundary layer on middle latitudes. In this study, we present the benefits coming from usage of small drones in atmospheric research. The experiment, described as a case study, was conducted at two stations (Swider and Warsaw) in Poland, from October 2014 to March 2015. For over 6 months, photoacoustic extinctiometers collected data at both stations. This enabled us to compare the stations and to establish ground reference of black carbon concentrations for vertical profiles collected by ceilometer and drone. At Swider station, we used Vaisala CL-31 ceilometer. It delivered vertical profiles of range corrected signal, which were analysed together with profiles acquired by micro-aethalometer AE-51 and Vaisala RS92-SGP radiosonde carried by a hexacopter drone. Near to the surface, black carbon gradient of ≈ 400 (\\upmu g/m^3 )/100 m was detected, which was below the ceilometer minimal altitude of detection. This confirmed the usefulness of drones and potential of their support for remote sensing techniques.

  7. Are Leadership and Management Essential for Good Research? An Interview Study of Genetic Researchers.

    Science.gov (United States)

    Antes, Alison L; Mart, Adelina; DuBois, James M

    2016-12-01

    Principal investigators are responsible for a myriad of leadership and management activities in their work. The practices they use to navigate these responsibilities ultimately influence the quality and integrity of research. However, leadership and management roles in research have received scant empirical examination. Semi-structured interviews with 32 National Institutes of Health (NIH)-funded genetic researchers revealed that they considered leadership and management essential for effective research, but their scientific training inadequately prepared them. We also report management practices that the researchers described using in their labs, as well as their perceptions of a proposed intervention to enhance laboratory leadership. These findings suggest best practices for the research community, future directions for scientific training, and implications for research on leadership and management in science.

  8. Are Leadership and Management Essential for Good Research? An Interview Study of Genetic Researchers

    Science.gov (United States)

    Antes, Alison L.; Mart, Adelina; DuBois, James M.

    2016-01-01

    Principal investigators are responsible for a myriad of leadership and management activities in their work. The practices they employ to navigate these responsibilities ultimately influence the quality and integrity of research. However, leadership and management roles in research have received scant empirical examination. Semi-structured interviews with 32 National Institutes of Health (NIH)-funded genetic researchers revealed that they considered leadership and management essential for effective research, but their scientific training inadequately prepared them. We also report management practices that the researchers described employing in their labs, as well as their perceptions of a proposed intervention to enhance laboratory leadership. These findings suggest best practices for the research community, future directions for scientific training, and implications for research on leadership and management in science. PMID:27646401

  9. The librarian as research informationist: a case study.

    Science.gov (United States)

    Federer, Lisa

    2013-10-01

    How can an embedded research informationist add value to the scientific output of research teams? The University of California-Los Angeles (UCLA) Louise M. Darling Biomedical Library is an academic health sciences library serving the clinical, educational, and research needs of the UCLA community. A grant from the National Library of Medicine funded a librarian to join a UCLA research team as an informationist. The informationist meets regularly with the research team and provides guidance related to data management, preservation, and other information-related issues. Early results suggest that the informationist's involvement has influenced the team's data gathering, storage, and curation methods. The UCLA Library has also changed the librarian's title to research informationist to reflect the new activities that she performs. The research informationist role provides an opportunity for librarians to become effective members of research teams and improve research output.

  10. RESEARCH STUDY ON THE BREEDING AVIFAUNA OF THE BASCOV RESERVOIR

    Directory of Open Access Journals (Sweden)

    Maria Denisa Conete

    2015-12-01

    Full Text Available The author conducted an ornithological study in the Bascov Reservoir area (a square of 2x2 km and observed 102 breeding species; 83 (81% of them are certain breeding species and 19 (19% are probable breeding species. The results of the research were cumulated with those found in the Atlas of the breeding species of Romania. By relating them with the Atlas data, we noted that 83 of the 100 breeding species cited in the Atlas were again recorded during our study. Nineteen new breeding species were identified. Among the species dependent on wetlands, mention should be made of Ixobrychus minutus, Anas platyrhynchos, Fulica atra, Gallinula chloropus, Aythya ferina, etc., with relatively large numbers of individuals. The analysis showed a relatively larger number (66 of euconstant and constant species, which confirmed the wealth of food resources in the area during the nesting period. The specific richness on the Bascov Lake is represented by 119 species, a number that is consistent with the availability of the food resources and nesting places, as well as the somewhat fluctuating presence of predators (stray dogs, and the anthropocentric disturbance (sound and chemical pollution, etc.. The yearly increase in the number of reed clusters, the expansion of the surface of the islets, the emergence of bushes and trees, the ageing of the existing trees have led to a certain yearly increase in the number of breeding individuals in 45 species. But the anthropogenic influence in the area has eventually contributed to a decrease in the number of birds, both as a number of species and as a number of individuals. The study has also shown that in the farmland bird species the number of individuals is in decline. Most of the breeding species - 75 (representing 74% in the area under research are migratory. Eighteen breeding species (17.64% are listed in Annex I of the Birds Directive. The presence of the key breeding species in the area under research must be

  11. Multidisciplinary research in public health: a case study of research on access to green space.

    Science.gov (United States)

    Kessel, A; Green, J; Pinder, R; Wilkinson, P; Grundy, C; Lachowycz, K

    2009-01-01

    perceptions and understandings of what is being accessed and how it should be used. This study has also illustrated the ways in which multiple methods can be integrated in public health research, and the merits of different approaches to undertaking multidisciplinary work of this type.

  12. Research Study on the Migration of Clients on Banking Market

    Directory of Open Access Journals (Sweden)

    Cornelia Tureac

    2013-02-01

    Full Text Available In this paper we present the relevancy and importance of knowing the reasons on clients’migration to competitive banking institutions. The main reason of being the client of several banks isdue to the fierce competition between credit institutions,thusthe banking market has changed. Basedon a case study within the Raiffeisen Bank we researched and presented the reasons fordiscontinuation of banking tiesand the migration of clients to other banks. The used researchmethodology consisted of the application of analysis point of contact by sending a questionnairethrough which there could have been identified 105 migrating clients, out of which 89 were formerclients of Raiffeisen Bank. Since both in the specialized literatureand in practice there is very littleinformation about migration behavior of banking clients-especially in the category of small andmedium enterprises-the present research was not limited to the Raiffeisen Bank clients, but to all 105respondents whodiscontinued totally or partially their connection with the bank. It can be concludedthat the attitude of the bank clients has a considerable influence on the migration behavior. The most“infidel” banking clients are considered in the category of “clients oriented towards the conditions.”

  13. Data management for community research projects: A JGOFS case study

    Science.gov (United States)

    Lowry, Roy K.

    1992-01-01

    Since the mid 1980s, much of the marine science research effort in the United Kingdom has been focused into large scale collaborative projects involving public sector laboratories and university departments, termed Community Research Projects. Two of these, the Biogeochemical Ocean Flux Study (BOFS) and the North Sea Project incorporated large scale data collection to underpin multidisciplinary modeling efforts. The challenge of providing project data sets to support the science was met by a small team within the British Oceanographic Data Centre (BODC) operating as a topical data center. The role of the data center was to both work up the data from the ship's sensors and to combine these data with sample measurements into online databases. The working up of the data was achieved by a unique symbiosis between data center staff and project scientists. The project management, programming and data processing skills of the data center were combined with the oceanographic experience of the project communities to develop a system which has produced quality controlled, calibrated data sets from 49 research cruises in 3.5 years of operation. The data center resources required to achieve this were modest and far outweighed by the time liberated in the scientific community by the removal of the data processing burden. Two online project databases have been assembled containing a very high proportion of the data collected. As these are under the control of BODC their long term availability as part of the UK national data archive is assured. The success of the topical data center model for UK Community Research Project data management has been founded upon the strong working relationships forged between the data center and project scientists. These can only be established by frequent personal contact and hence the relatively small size of the UK has been a critical factor. However, projects covering a larger, even international scale could be successfully supported by a

  14. STUDY OF TRENDS AND PERSPECTIVES OF INDUSTRIAL ENGINEERING RESEARCH

    Directory of Open Access Journals (Sweden)

    H. Dastkhan

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: Industrial engineering is an engineering discipline which, because of its multi-disciplinary nature, has played an important role in the development and optimization of different systems at macro and micro levels. In this paper, the results of a research to study the position and trend of Industrial Engineering research in recent years are described. The data from a sample of 7 114 IE-related articles from international journals during the last 27 years were used for the analysis. The results showed that the development of IE in many countries has a strong correlation with their industrial and economic development. However, IE research topics are spreading in other management and engineering departments and so there is a need to redefine the discipline and its specific areas of interest. According to the prediction made using time series analysis, the most favorite fields of IE research in future will be on subjects related to information technology, intelligent systems, optimization, quality, and supply chain management.

    AFRIKAANSE OPSOMMING: Bedryfsingenieurswese is 'n ingenieursdissipline wat vanweë die multi-dissiplinêre aard daarvan 'n belangrike rol gespeel het in die optimisering van verskillende sisteme op makroen mikrovlak. Hierdie artikel hou die resultate voor van 'n navorsingsprojek wat onderneem is om die posisie en rigting van Bedryfsingenieursnavorsing in onlangse jare te bepaal. Die data van 'n monster van 7 114 Bedryfsingenieursverwante artikels wat verskyn het in internasionale joernale oor die afgelope 27 jaar is gebruik vir die ontleding. Die resultate toon dat die groei van Bedryfsingenieurswese in verskeie lande sterk korreleer met industriële en ekonomiese ontwikkeling. Tog blyk dit dat die navorsingsonderwerpe van Bedryfsingenieurswese sprei na ander bestuurs- en ingenieursdepartemente en dus bestaan daar ‘n nodigheid om die dissipline en die spesifieke belangstellingsvelde te herdefinieer

  15. How Do They Research? An Ethnographic Study of Final Year Undergraduate Research Behavior in an Irish University

    Science.gov (United States)

    Dunne, Siobhán

    2016-01-01

    The objectives of this study were to identify how, when, and where students research; the impact of learning environments on research productivity, and to recommend improved supports to facilitate research. An ethnographic approach that entailed following five students in the final six weeks of their program enabled deep level analysis. The study…

  16. Collaborative research between clinicians and researchers: a multiple case study of implementation

    Directory of Open Access Journals (Sweden)

    Edlund Carrie

    2010-10-01

    Full Text Available Abstract Background Bottom-up, clinician-conceived and directed clinical intervention research, coupled with collaboration from researcher experts, is conceptually endorsed by the participatory research movement. This report presents the findings of an evaluation of a program in the Veterans Health Administration meant to encourage clinician-driven research by providing resources believed to be critical. The evaluation focused on the extent to which funded projects: maintained integrity to their original proposals; were methodologically rigorous; were characterized by collaboration between partners; and resulted in sustained clinical impact. Methods Researchers used quantitative (survey and archival and qualitative (focus group data to evaluate the implementation, evaluation, and sustainability of four clinical demonstration projects at four sites. Fourteen research center mentors and seventeen clinician researchers evaluated the level of collaboration using a six-dimensional model of participatory research. Results Results yielded mixed findings. Qualitative and quantitative data suggested that although the process was collaborative, clinicians' prior research experience was critical to the quality of the projects. Several challenges were common across sites, including subject recruitment, administrative support and logistics, and subsequent dissemination. Only one intervention achieved lasting clinical effect beyond the active project period. Qualitative analyses identified barriers and facilitators and suggested areas to improve sustainability. Conclusions Evaluation results suggest that this participatory research venture was successful in achieving clinician-directed collaboration, but did not produce sustainable interventions due to such implementation problems as lack of resources and administrative support.

  17. Research

    African Journals Online (AJOL)

    2014-05-06

    May 6, 2014 ... facilitate and support articulation between the ECT mid-level worker qualification and the professional B EMC degree. Methods. The researchers used an exploratory, sequential mixed-method design, which is characterised by a qualitative phase of research followed by a quantitative phase. This design is ...

  18. Research

    African Journals Online (AJOL)

    supports medical education and research at institutions in 12 ... (CBE). CapacityPlus, led by IntraHealth International, is the USAID-funded ... acquire public health, clinical, and/or research skills, usually through applied learning in a .... If students were evaluated, indicate the type of student (i.e. medical, dental, nursing, etc.) ...

  19. Research

    African Journals Online (AJOL)

    abp

    2017-01-24

    Jan 24, 2017 ... and the specific rotavirus VP4 (P-types) and VP7 (G-types) determined. Results: The .... Centre for Virus Research (CVR) of the Kenya Medical Research. Institute (KEMRI) ... rotavirus dsRNA was run on 10% polyacrylamide resolving gels using a large format .... What is known about this topic. •. Rotavirus is ...

  20. Growth and development studies Hiroshima and Nagasaki: research plan

    Energy Technology Data Exchange (ETDEWEB)

    Finch, S C; Jablon, S; Hrubec, Zdenek

    1962-03-21

    This report summarizes the research plan for prospective evaluation of growth and development in those exposed to varying amounts of ionizing radiation during childhood or while in utero in Hiroshima or Nagasaki. Some experimental observations are briefly presented to provide background information, and the results of previous studies of growth and development at the Atomic Bomb Casualty Commission (ABCC) are reviewed. Procedures have been described for determining the top of the growth curve for the in utero exposed and the maximum growth and development of those exposed during childhood in comparison to their nonexposed counterparts. Differences in growth and development found between exposed and nonexposed individuals will be analysed in relation to radiation dose, age at time of exposure, sex, and socioeconomic factors. Attempts will be made to determine whether or not abnormalities in visual acuity are increased in those exposed while in utero or during childhood as compared to nonexposed or comparable ages. 23 references, 2 tables.

  1. Method of research and study of uranium deposits

    International Nuclear Information System (INIS)

    Lenoble, A.

    1955-01-01

    In a first part, the author gives a fast retrospective of the evaluations of the uranium deposits in the French Union. The author established a method of prospecting and studying, modifiable at all times following the experiences and the results, permitting to make the general inventory of uranium resources on the territory. The method is based on: 1 - the determination of geological guides in order to mark the most promising deposits, 2 - the definition of a methodology adapted to every steps of the research, 3 - the choice of the material adapted for each of the steps. This method, originally established for the prospecting in crystalline massifs, is adaptable to the prospecting of the sedimentary formations. (M.B.) [fr

  2. Broadband Seismic Studies at the Mallik Gas Hydrate Research Well

    Science.gov (United States)

    Sun, L. F.; Huang, J.; Lyons-Thomas, P.; Qian, W.; Milkereit, B.; Schmitt, D. R.

    2005-12-01

    The JAPEX/JNOC/GSC et al. Mallik 3L-38, 4L-38 and 5L-38 scientific wells were drilled in the MacKenzie Delta, NWT, Canada in early 2002 primarily for carrying out initial tests of the feasibility of producing methane gas from the large gas hydrate deposits there [1]. As part of this study, high resolution seismic profiles, a pseudo-3D single fold seismic volume and broadband (8~180Hz) multi-offset vertical seismic profiles (VSP) were acquired at the Mallik site. Here, we provide details on the acquisition program, present the results of the 2D field profile, and discuss the potential implications of these observations for the structure of the permafrost and gas hydrate zones. These zones have long been problematic in seismic imaging due to the lateral heterogeneities. Conventional seismic data processing usually assume a stratified, weak-contrast elastic earth model. However, in permafrost and gas hydrate zones this approximation often becomes invalid. This leads to seismic wave scattering caused by multi-scale perturbation of elastic properties. A 3D viscoelastic finite difference modeling algorithm was employed to simulate wave propagation in a medium with strong contrast. Parameters in this modeling analysis are based on the borehole geophysical log data. In addition, an uncorrelated Vibroseis VSP data set was studied to investigate frequency-dependent absorption and velocity dispersion. Our results indicate that scattering and velocity dispersion are important for a better understanding of attenuation mechanisms in heterogeneous permafrost and gas hydrate zones. [1] Dallimore, S.R., Collett, T.S., Uchida, T., and Weber, M., 2005, Overview of the science program for the Mallik 2002 Gas Hydrate Production Research Well Program; in Scientific Results from Mallik 2002 Gas Hydrate production Research Well Program, MacKenzie Delta, Northwest Territories, Canada, (ed.) S.R. Dallimore and T.S. Collett; Geological Survey of Canada, Bulletin 585, in press.

  3. survey research in practical theology and congregational studies

    African Journals Online (AJOL)

    such as the social, political and economic environment that influence society also affect the ... correlation research is part of a quantitative research methodology and could contribute to ... Another type is qualitative survey that focuses on the ...

  4. Case studies of market research for three transportation communication products

    Science.gov (United States)

    1994-03-01

    This report completes a two-part project in support of the Volpe Center program, Public Acceptance and Markets for Various IVHS Services. The first report, A Primer on Marketing Research, provides an overview of the research approaches an...

  5. Inclination towards research and the pursuit of a research career among medical students: an international cohort study.

    Science.gov (United States)

    Ha, Tam Cam; Ng, Sheryl; Chen, Cynthia; Yong, Sook Kwin; Koh, Gerald C H; Tan, Say Beng; Malhotra, Rahul; Altermatt, Fernando; Seim, Arnfinn; Biderman, Aya; Woolley, Torres; Østbye, Truls

    2018-05-02

    Involvement of clinicians in biomedical research is imperative for the future of healthcare. Several factors influence clinicians' inclination towards research: the medical school experience, exposure to research article reading and writing, and knowledge of research. This cohort study follows up medical students at time of graduation to explore changes in their inclination towards research and pursuing a research career compared to their inclination at time of entry into medical school. Students from medical schools in six different countries were enrolled in their first year of school and followed-up upon graduation in their final year. Students answered the same self-administered questionnaire at both time points. Changes in inclination towards research and pursuing a research career were assessed. Factors correlated with these changes were analysed. Of the 777 medical students who responded to the study questionnaire at entry into medical school, 332 (42.7%) completed the follow-up survey. Among these 332 students, there was no significant increase in inclination towards research or pursuing a research career over the course of their medical schooling. Students from a United States based school, in contrast to those from schools other countries, were more likely to report having research role models to guide them (51.5% vs. 0%-26.4%) and to have published in a peer-reviewed journal (75.7% vs. 8.9%-45%). Absence of a role model was significantly associated with a decrease in inclination towards research, while an increased desire to learn more about statistics was significantly associated with an increase in inclination towards pursuing a research career. Most medical students did not experience changes in their inclination towards research or pursuing a research career over the course of their medical schooling. Factors that increased their inclination to undertaking research or pursuing a research career were availability of a good role model, and a good

  6. Standards for Reporting Mathematics Professional Development in Research Studies

    Science.gov (United States)

    Sztajn, Paola

    2011-01-01

    This Research Commentary addresses the need for standards for describing mathematics professional development in mathematics education research reports. Considering that mathematics professional development is an emerging research field, it is timely to set expectations for what constitutes high-quality reporting in this field. (Contains 2 tables.)

  7. Blurring the Line between Researcher and Researched in Interview Studies: A Feminist Practice?

    Science.gov (United States)

    Yost, Megan R.; Chmielewski, Jennifer F.

    2013-01-01

    This commentary is intended to serve as a companion to the authors' original research article ("Psychosocial Influences on Bisexual Women's Body Image Negotiating Gender and Sexuality," "Psychology of Women Quarterly," v37 n2 p224-241 Jun 2013) and to contribute to the conversation on feminist research methods. In it,…

  8. Research

    African Journals Online (AJOL)

    abp

    2017-10-25

    Oct 25, 2017 ... stigma and superstition are known to lead to frequent presentation .... The limited documented research on challenges to help-seeking behaviour for cancer ..... to touch your breast [16] that breast self-examination may cause.

  9. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-10-02

    Oct 2, 2015 ... thought to prevent infection, but recent research has proven otherwise. In addition ... One patient had ophthalmalgia and was exposed to. Kaiy for one year and ... migraine, ear infections, tuberculosis, bone fractures, epilepsy,.

  10. Research

    International Nuclear Information System (INIS)

    1999-01-01

    Subjects covered in this section are: (1) PCAST panel promotes energy research cooperation; (2) Letter issued by ANS urges funding balance in FFTF restart consideration and (3) FESAC panel releases report on priorities and balance

  11. Integrated Risk Research. Case of Study: Motozintla, Chiapas, Mexico

    Science.gov (United States)

    Novelo-Casanova, D. A.; Jaimes, M.

    2015-12-01

    This integrated risk research include the analysis of all components of individual constituents of risk such hazard identification, hazard exposure, and vulnerability. We determined risk to natural hazards in the community of Motozintla located in southern Mexico in the state of Chiapas (15.37ºN, 92.25ºW. Due to its geographical and geological location, this community is continuously exposed mainly to earthquakes, landslides and floods. We developed integrated studies and analysis of seismic zonation, landslides and flood susceptibility using standard methodologies. Vulnerability was quantified from data collected from local families interviews considering five social variables: characteristics of housing construction, availability of basic public services, family economic conditions, existing community plans for disaster preparedness, and risk perception. Local families surveyed were randomly selected considering a sample statistically significant. Our results were spatially represented using a Geographical Information System (GIS). Structural vulnerability curves were generated for typical housing constructions. Our integrated risk analysis demonstrates that the community of Motozintla has a high level of structural and socio-economical risk to floods and earthquakes. More than half of the population does not know any existing Civil Protection Plan and perceive that they are in high risk to landslides and floods. Although the community is located in a high seismic risk zone, most of the local people believe that cannot be impacted by a large earthquake. These natural and social conditions indicate that the community of Motozintla has a very high level of risk to natural hazards. This research will support local decision makers in developing an integrated comprehensive natural hazards mitigation and prevention program.

  12. Exploring interprofessional, interagency multimorbidity care: case study based observational research

    Science.gov (United States)

    McKinlay, Eileen M.; Morgan, Sonya J.; Gray, Ben V.; Macdonald, Lindsay M.; Pullon, Susan R.H.

    2017-01-01

    Background The increase in multimorbidity or co-occurring chronic illnesses is a leading healthcare concern. Patients with multimorbidity require ongoing care from many different professionals and agencies, and often report a lack of integrated care. Objective To explore the daily help-seeking behaviours of patients with multimorbidity, including which health professionals they seek help from, how professionals work together, and perceptions and characteristics of effective interprofessional, interagency multimorbidity care. Design Using a case study observational research design, multiple data sources were assembled for four patients with multimorbidity, identified by two general practitioners in New Zealand. In this paper, two case studies are presented, including the recorded instances of contact and communication between patients and professionals, and between professionals. Professional interactions were categorized as consultation, coordination, or collaboration. Results The two case studies illustrated two female patients with likely similar educational levels, but with different profiles of multimorbidity, social circumstances, and personal capabilities, involving various professionals and agencies. Engagement between professionals showed varying levels of interaction and a lack of clarity about leadership or care coordination. The majority of interactions were one-to-one consultations and rarely involved coordination and collaboration. Patients were rarely included in communications between professionals. Conclusion Cases constructed from multiple data sources illustrate the complexity of day-to-day, interprofessional, interagency multimorbidity care. While consultation is the most frequent mode of professional interaction, targeted coordinated and collaborative interactions (including the patient) are highly effective activities. Greater attention should be given to developing and facilitating these interactions and determining who should lead them. PMID

  13. Personality traits are associated with research misbehavior in Dutch scientists : A cross-sectional study

    NARCIS (Netherlands)

    Tijdink, Joeri; Bouter, Lex; Veldkamp, C.L.S.; van de Ven, Peter; Wicherts, J.M.; Smulders, Yvo; Dorta-González, Pablo

    2016-01-01

    Background Personality influences decision making and ethical considerations. Its influence on the occurrence of research misbehavior has never been studied. This study aims to determine the association between personality traits and self-reported questionable research practices and research

  14. Study on Lexical Cohesion in English and Persian Research Articles (A Comparative Study)

    Science.gov (United States)

    Mirzapour, Fatemeh; Ahmadi, Maryam

    2011-01-01

    The present study aims to analyze comparatively English and Persian research articles (Linguistics, Literature, and Library and Information disciplines) in terms of number and degree of utilization of sub-types of lexical cohesion in order to appreciate textualization processes in the two languages concerned. The study analyzes 60 research…

  15. Researchers studying alternative to bladder removal for bladder cancer patients | Center for Cancer Research

    Science.gov (United States)

    A new phase I clinical trial conducted by researchers at the Center for Cancer Research (CCR) is evaluating the safety and tolerability, or the degree to which any side effects can be tolerated by patients, of a two-drug combination as a potential alternative to bladder removal for bladder cancer patients. The trial targets patients with non-muscle invasive bladder cancer (NMIBC) whose cancers have stopped responding to traditional therapies. Read more...

  16. Why, and how, mixed methods research is undertaken in health services research in England: a mixed methods study

    Science.gov (United States)

    O'Cathain, Alicia; Murphy, Elizabeth; Nicholl, Jon

    2007-01-01

    Background Recently, there has been a surge of international interest in combining qualitative and quantitative methods in a single study – often called mixed methods research. It is timely to consider why and how mixed methods research is used in health services research (HSR). Methods Documentary analysis of proposals and reports of 75 mixed methods studies funded by a research commissioner of HSR in England between 1994 and 2004. Face-to-face semi-structured interviews with 20 researchers sampled from these studies. Results 18% (119/647) of HSR studies were classified as mixed methods research. In the documentation, comprehensiveness was the main driver for using mixed methods research, with researchers wanting to address a wider range of questions than quantitative methods alone would allow. Interviewees elaborated on this, identifying the need for qualitative research to engage with the complexity of health, health care interventions, and the environment in which studies took place. Motivations for adopting a mixed methods approach were not always based on the intrinsic value of mixed methods research for addressing the research question; they could be strategic, for example, to obtain funding. Mixed methods research was used in the context of evaluation, including randomised and non-randomised designs; survey and fieldwork exploratory studies; and instrument development. Studies drew on a limited number of methods – particularly surveys and individual interviews – but used methods in a wide range of roles. Conclusion Mixed methods research is common in HSR in the UK. Its use is driven by pragmatism rather than principle, motivated by the perceived deficit of quantitative methods alone to address the complexity of research in health care, as well as other more strategic gains. Methods are combined in a range of contexts, yet the emerging methodological contributions from HSR to the field of mixed methods research are currently limited to the single

  17. Radiation protection research and studies after the Chernobyl accident

    International Nuclear Information System (INIS)

    Madelmont, C.; Coulon, R.; Legrand, B.; Manesse, D.; Rzepka, J.P.

    1989-04-01

    The effects on the environment of the Chernobyl Power Plant accident, which happened in the reactors unit 4, are analyzed. The aim of the study is to show the main fields of research and development to be considered, in order to improve the knowledge on public or local radiation protection. The following aspects of the problem are discussed: the long range atmospheric transfer, the environment monitoring, the problems related to the food chain transfers, the environment recovery and the estimation of the sanitary effects. The Chernobyl disaster confirms: the priority of special plans of action to protect the surrounding population; that the special plans of action must be followed by after-disaster actions, which take into account methods for the environment recovery; that the conventional systematic approach can not be satisfactorily applied to manage such a critical situation, and a new one must be developed. Moreover, the identification of the most exposed (population) groups, far from the nearby affected area, are to be considered [fr

  18. Studies on fuel failure detection in Rikkyo Research Reactor

    International Nuclear Information System (INIS)

    Matsuura, T.; Hayashi, S.H.; Harasawa, S.; Tomura, K.

    1992-01-01

    Studies on fuel failure detection have been made since 1986 in Rikkyo Research Reactor. One of the methods is the monitoring of the trace concentration of fission products appearing in the air on the surface of the water tank of the reactor. The interested radionuclides here are 89 Rb and 138 Cs, which are the daughter nuclides of the FP rare gas nuclides, 89 Kr and 138 Xe, respectively and have the half lives of 15.2 min and 32.2 min respectively. They are detected on a filter paper attached on a conventional dust sampler, by sucking the air of the surface of the water for 15 ∼ 30 min during reactor operation (100 kW). In this presentation are reported the results of an attempt to increase the sensitivity of detecting these nuclides by introducing nitrogen gas bubbles into the water. The bubbling of the gas increased the sensitivity as much as several times compared with the case without bubbling. These measurements are giving us the 'background' concentration, the order of which is almost unchanged for these several years, --in 10 -6 Bq/cm 3 . The origin of these nuclides is considered to be not from the fuel but from the uranium contained as an impurity in the reactor material in the core. (author)

  19. In silico studies in drug research against neurodegenerative diseases.

    Science.gov (United States)

    Makhouri, Farahnaz Rezaei; Ghasemi, Jahan B

    2017-08-22

    Neurodegenerative diseases such as Alzheimer's disease (AD), progressive neurodegenerative forms of Huntington's disease, Parkinson's disease (PD), amyotrophic lateral sclerosis, spinal cerebellar ataxias, and spinal and bulbar muscular atrophy are described by slow and selective dysfunction and degeneration of neurons and axons in the central nervous system (CNS). Computer-aided or in silico design methods have matured into powerful tools for reducing the number of ligands that should be screened in experimental assays. In the present review, the authors provide a basic background about neurodegenerative diseases and in silico techniques in the drug research. Furthermore, they review the various in silico studies reported against various targets in neurodegenerative diseases, including homology modeling, molecular docking, virtual high-throughput screening, quantitative structure activity relationship (QSAR), hologram quantitative structure activity relationship (HQSAR), 3D pharmacophore mapping, proteochemometrics modeling (PCM), fingerprints, fragment-based drug discovery, Monte Carlo simulation, molecular dynamic (MD) simulation, quantum-mechanical methods for drug design, support vector machines, and machine learning approaches. Neurodegenerative diseases have a multifactorial pathoetiological origin, so scientists have become persuaded that a multi-target therapeutic strategy aimed at the simultaneous targeting of multiple proteins (and therefore etiologies) involved in the development of a disease is recommended in future. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  20. Radiation exposure of fertile women in medical research studies

    International Nuclear Information System (INIS)

    Vetter, R.J.

    1988-01-01

    Fertile women may be exposed to ionizing radiation as human subjects in medical research studies. If the woman is pregnant, such exposures may result in risk to an embryo/fetus. Fertile women may be screened for pregnancy before exposure to ionizing radiation by interview, general examination, or pregnancy test. Use of the sensitive serum pregnancy test has become common because it offers concrete evidence that the woman is not pregnant (more specifically, that an embryo is not implanted). Evidence suggests that risk to the embryo from radiation exposure before organogenesis is extremely low or nonexistent. Further, demonstrated effects on organogenesis are rare or inconclusive at fetal doses below 50 mSv (5 rem). Therefore, there may be some level of radiation exposure below which risk to the fetus may be considered essentially zero, and a serum pregnancy test is unnecessary. This paper reviews the fetal risks and suggests that consideration be given to establishing a limit to the fetus of 0.5 mSv (50 mrem), below which pregnancy screening need not include the use of a serum pregnancy test

  1. Studies and researches in the underground laboratory at Pasquasia mine

    International Nuclear Information System (INIS)

    Tassoni, E.; Cautilli, F.; Polizzano, C.; Zarlenga, F.

    1989-01-01

    The reliability of the geological disposal of radioactive wastes has to be verified both by laboratory and on site researches, under both surface and underground conditions. The tests carried out under high lithostatic stress can allow extrapolations to be made having absolute value at the depths planned for the construction of the repository. An underground laboratory was excavated at the Pasquasia mine (Enna-Sicilia). On the selected area a detailed geological survey (1:5000 scale) was carried out; for the purpose of studying the effects induced by the advancement of the excavation's face into the clayey mass and over the cross section of the transversal tunnel, several geotechnical measurement stations were installed. Structural observations were made on both the fronts and the walls of the tunnel for the purpose of characterizing the mechanical behaviour of the clayey mass. The 37 cubic blocks and the 72 samples collected during the excavation were analyzed from different point of view (sedimentological, mineralogical, geotechnical, etc.). After the excavation of the tunnel and the installation of the geotechnical stations, the measurements were carried out up to March 1987. At this date the work programme was unfortunately stopped by local authorities, unfoundly suspecting Pasquasia mine would be used as waste repository

  2. Fate of clinical research studies after ethical approval--follow-up of study protocols until publication.

    Directory of Open Access Journals (Sweden)

    Anette Blümle

    Full Text Available Many clinical studies are ultimately not fully published in peer-reviewed journals. Underreporting of clinical research is wasteful and can result in biased estimates of treatment effect or harm, leading to recommendations that are inappropriate or even dangerous.We assembled a cohort of clinical studies approved 2000-2002 by the Research Ethics Committee of the University of Freiburg, Germany. Published full articles were searched in electronic databases and investigators contacted. Data on study characteristics were extracted from protocols and corresponding publications. We characterized the cohort, quantified its publication outcome and compared protocols and publications for selected aspects.Of 917 approved studies, 807 were started and 110 were not, either locally or as a whole. Of the started studies, 576 (71% were completed according to protocol, 128 (16% discontinued and 42 (5% are still ongoing; for 61 (8% there was no information about their course. We identified 782 full publications corresponding to 419 of the 807 initiated studies; the publication proportion was 52% (95% CI: 0.48-0.55. Study design was not significantly associated with subsequent publication. Multicentre status, international collaboration, large sample size and commercial or non-commercial funding were positively associated with subsequent publication. Commercial funding was mentioned in 203 (48% protocols and in 205 (49% of the publications. In most published studies (339; 81% this information corresponded between protocol and publication. Most studies were published in English (367; 88%; some in German (25; 6% or both languages (27; 6%. The local investigators were listed as (co-authors in the publications corresponding to 259 (62% studies.Half of the clinical research conducted at a large German university medical centre remains unpublished; future research is built on an incomplete database. Research resources are likely wasted as neither health care

  3. Balancing research interests and patient interests: a qualitative study into the intertwinement of care and research in paediatric oncology.

    Science.gov (United States)

    Dekking, Sara A S; van der Graaf, Rieke; Kars, Marijke C; Beishuizen, Auke; de Vries, Martine C; van Delden, Johannes J M

    2015-05-01

    Traditionally, in ethical guidelines and in research ethics literature, care and research are clearly separated based on their different objectives. In contrast, in paediatric oncology, research and care are closely combined. Currently, it is unknown how relevant actors in paediatric oncology perceive this combination of research and care. We conducted a qualitative study into the experiences of those involved in Dutch paediatric oncology with the intertwinement of research and care and the dual role of paediatric oncologists as researchers and treating physicians. A qualitative study approach, using two focus groups and 19 semi-structured, in-depth interviews with paediatric oncologists, research coordinators, parents of children with cancer, and adolescents with cancer. Four themes characterize how actors experience the intertwinement of research and care in paediatric oncology. First, research is considered of major importance, and paediatric oncology professionals convey this message to patients and their parents. Second, there is ambiguity about categorization of studies into cancer therapy as either research or treatment. Third, role conflicts appear within the work of the paediatric oncologists. Finally, the various benefits of combining treatment with research are emphasized. Research is regarded as a fundamental and indispensable characteristic of paediatric oncology practice. Paediatric oncology professionals, parents, and patients have a very positive outlook on combining research and care, but they may not be sufficiently critical with respect to potential conflicts. Increased reflection on how to optimally combine research and care could serve as an important protection of the interests of children with cancer and their parents. © 2015 Wiley Periodicals, Inc.

  4. International Students on an American Campus: An Undergraduate Research Study.

    Science.gov (United States)

    Matthews, Judith; Quattrocki, Carolyn

    1981-01-01

    Describes a seminar in which undergraduate students in home economics were provided with research training and the opportunity to work together on a research project which included housing, clothing, nutrition, consumer services, child development, and family relations. Students also explored difficulties international students encounter in…

  5. Globalisation, the Research Imagination and Deparochialising the Study of Education

    Science.gov (United States)

    Lingard, Bob

    2006-01-01

    This paper works in dialogue with Arjun Appadurai's paper, "Grassroots globalization and the research imagination" in an attempt to outline some necessary changes in researching education in the multiple contexts of globalisation. The paper provides two narratives as part of this project, which Appadurai calls the…

  6. Credible Phenomenological Research: A Mixed-Methods Study

    Science.gov (United States)

    Flynn, Stephen V.; Korcuska, James S.

    2018-01-01

    The authors conducted a 3-phase investigation into the credible standards for phenomenological research practices identified in the literature and endorsed by a sample of counselor education qualitative research experts. Utilizing a mixed-methods approach, the findings offer evidence that professional counseling has a distinctive format in which…

  7. The Undergraduate as Researcher: Selected Studies in Mass Communication.

    Science.gov (United States)

    Felsenthal, Norman A.

    Reporting on a group of class projects undertaken by a series of his college-level "Broadcasting and Society" courses, the author concludes that there is great value in encouraging undergraduates to do their own original research. Among the topics researched by the students are the effect of television on nuns, television news viewing habits of…

  8. Critical-Cultural Studies in Research and Instruction.

    Science.gov (United States)

    Switzer, Les; McNamara, John; Ryan, Michael

    1999-01-01

    Outlines two paradigms in critical-cultural analysis that seek to identify and explain the meaning of phenomena that make a culture, focusing on their relevance to research and teaching in journalism and mass communication. Identifies key issues and implications for mass communication research and teaching. Suggests ways educators can apply…

  9. Can informetrics shape biomedical research? A case study of the ...

    African Journals Online (AJOL)

    Biomedical research is burgeoning as new dangerous diseases and healing methods emerge. Informetrics defined as methods or a research field that uses mathematical and statistical techniques and/or models to examine patterns that show up not only in publications but also in many aspects of life, as long as the patterns ...

  10. Practice as Research: A Fine Art Contextual Study

    Science.gov (United States)

    Adams, Suze

    2014-01-01

    This paper examines the dynamic interplay between practice and theory in practice-led research in the visual arts. Building on recent debate around the issue and following appropriately rigorous models, the importance of locating a suitable methodology to adequately reflect the integrated process of research practice in written as well as visual…

  11. CASE STUDY: Lebanon — Researchers find new ways to resolve ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-12-13

    Dec 13, 2010 ... Communication is the key to conflict resolution A research team in ... as a model for a new applied research unit at the American University of Beirut. ... The LUN, for example, created a forum for discussing problems and ...

  12. Student Approaches to Learning and Studying. Research Monograph.

    Science.gov (United States)

    Biggs, John B.

    A common thread in contemporary research in student learning refers to the ways in which students go about learning. A theory of learning is presented that accentuates the interaction between the person and the situation. Research evidence implies a form of meta-cognition called meta-learning, the awareness of students of their own learning…

  13. Legitimating Clinical Research in the Study of Organizational Culture.

    Science.gov (United States)

    Schein, Edgar H.

    1993-01-01

    Argues that traditional research model used in industrial-organizational psychology is not useful in understanding deeper dynamics of organizations, especially those phenomena labeled as "cultural." Contends that use of data obtained during clinical and consulting work should be legitimated as valid research data. Spells out clinical model and…

  14. Study of mass consciousnessand its dynamics in sociologic research

    Directory of Open Access Journals (Sweden)

    S. V. Khobta

    2017-01-01

    Full Text Available The article is dedicated to analysis of the approaches used to study mass consciousness and the methods of their dynamics research. The two following approaches are reviewed: aggregative and group. The author shows that the study of the dynamics of mass consciousness in the modern day science is performed via computer modeling applying agent-oriented models and mass surveys of public opinion. Special attention is given to the concept of mass consciousness according to B. Grushin, where the mass consciousness is analyzed as a complex phenomenon according to its structure and the formation process. It is further analyzed what this particular concept is able to provide for the mass consciousness studies in the times of crises, similar to the situation of the military conflict at the East. It is then proven that the dialectic approach should be used as the basis for the mass consciousness studies adjusted for the interaction dynamics between the individual and collective, spontaneous and the institutionalized inside the collective consciousness. The mass consciousness is a complex structural formation, both heterogeneous and syncretical. Inside this structure one must distinguish between the layers that differ in depth and mobility and pay attention to its various conditions. The layers represent different worldviews, where, depending on the situation, scientific, religious or mystical images of the world can be actualized along with their ideological, moral and aesthetic precepts. These can cross, merge or coexist without contradicting each other and get actualized to a different extent. Besides the aforementioned the mass consciousness serves as a carrier of different kinds of deep, hard to change formations, such as «historical/collective memory», memlexes as well as superficial, most actualized forms, such as mems. It has «public/formal», socially accepted, and «private/real» levels that manifest themselves, in particular, in the forms of

  15. Research

    African Journals Online (AJOL)

    abp

    2017-05-18

    May 18, 2017 ... available to populations of developing countries [2-5]. In 2013, in. Western and Central Europe and ..... initiation among the infected persons in the community. Addressing stigma and educating ... Lifespan/Tufts/Brown Center for AIDS Research (P30AI042853). Tables. Table 1: Baseline characteristics of ...

  16. Research

    African Journals Online (AJOL)

    abp

    15 févr. 2016 ... présentent un Indice de Masse Corporel (IMC) normal, les autres femmes sont soit ..... In The health belief model and personal health behavior, edited by MH ... Evaluation of the Osteoporosis Health Belief Scale. Research in.

  17. Research

    African Journals Online (AJOL)

    2017-03-14

    Mar 14, 2017 ... R Ebrahim,1 MSc (Dent); H Julie,2 MPH, MCur, PhD. 1 Extended ... and research is applied to develop and sustain society.[5]. Methods .... service they want, not the service we want to give whether they want it or. Co math. G.

  18. Research

    African Journals Online (AJOL)

    abp

    2017-11-24

    Nov 24, 2017 ... Page number not for citation purposes. 1. Prevalence and determinants of common mental ..... illnesses were smoke cigarette in the last 3 months that make prevalence of tobacco use 38.2%. ..... Okasha A, Karam E.Mental health services and research in the. Arab world. Acta Psychiatrica Scandinavica.

  19. Research

    African Journals Online (AJOL)

    abp

    2014-04-21

    Apr 21, 2014 ... Prospective assessment of the risk of obstructive sleep apnea in ... Faculty of Clinical Sciences, College of Medicine, University of .... University Teaching Hospital Health Research Ethics Committee ... BANG, Berlin questionnaire and the American Society of .... The epidemiology of adult obstructive sleep.

  20. Research

    African Journals Online (AJOL)

    abp

    2015-06-24

    Jun 24, 2015 ... related immunosuppression, previous history of TB, and pause in treatment [6]. In Brazil, researchers .... treatment, use of traditional medicines or herbs, history of TB drug side effects and treatment delay). ..... therapy for pulmonary tuberculosis in Lima Ciudad, Peru. International journal of tuberculosis and ...

  1. Research

    African Journals Online (AJOL)

    Research. May 2016, Vol. 8, No. 1 AJHPE 37. Students who enrol in occupational therapy (OT) at the. University of Kwa Zulu-Natal (UKZN), Durban, South Africa ... The latter may include becoming familiar with the disintegrating social systems in primary .... They also lacked the skills needed to adapt sessions and failed to ...

  2. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-06-22

    Jun 22, 2015 ... collaboration with Makerere University, School of Public Health. We acknowledge The Family Health Research and Development Centre. (FHRDC) Uganda. Supported by Bill & Melinda Gates Institute for. Population & Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, ...

  3. Research

    African Journals Online (AJOL)

    However, a focus on competence alone is inadequate to produce graduates who are capable of adapting to the changing needs of health systems. While knowledge and technical ... shared their responses to guided questions. There were three sessions; after each session the researcher aggregated participant responses ...

  4. Research

    African Journals Online (AJOL)

    2018-03-20

    Mar 20, 2018 ... student health professionals in various institutions, both in South Africa. (SA) and internationally. ... field include dentists, dental therapists and oral hygienists in training, .... The College of Health Sciences at UKZN has four schools: clinical ..... Journal of Emerging Trends in Educational Research and Policy ...

  5. Research

    African Journals Online (AJOL)

    abp

    2017-09-14

    Sep 14, 2017 ... Abstract. Introduction: Medical and dental students are a high-risk group for hepatitis B virus (HBV) infection which is an ... The Pan African Medical Journal - ISSN 1937-8688. ... Research ... in the College of Health Sciences and clinical students (years four to .... Hepatology International.2017 Jan; 11(1):.

  6. Research

    African Journals Online (AJOL)

    abp

    2015-01-19

    Jan 19, 2015 ... One research assistant was available to assist the learners and to answer questions while they completed the questionnaires during a classroom period. ..... PubMed | Google Scholar. 4. Hall PA, Holmqvist M, Sherry SB. Risky adolescent sexual behaviour: A psychological perspective for primary care.

  7. Current Research at the Endeavour Ridge 2000 Integrated Studies Site

    Science.gov (United States)

    Butterfield, D. A.; Kelley, D. S.; Ridge 2000 Community, R.

    2004-12-01

    Integrated geophysical, geological, chemical, and biological studies are being conducted on the Endeavour segment with primary support from NSF, the W.M. Keck Foundation, and NSERC (Canada). The research includes a seismic network, physical and chemical sensors, high-precision mapping and time-series sampling. Several research expeditions have taken place at the Endeavour ISS in the past year. In June 2003, an NSF-sponsored cruise with R.V. al T.G.Thompson/ROV al Jason2 installed microbial incubators in drill-holes in the sides of active sulfide chimneys and sampled rocks, fluids, and microbes in the Mothra and Main Endeavour Field (MEF). In July 2003, with al Thompson/Jason2, an NSF-LEXEN project at Baby Bare on Endeavour east flank conducted sampling through seafloor-penetrating probes, plus time-series sampling of fluids, microbes, and rocks at the MEF. In September 2003, with al Thompson/ROV al ROPOS, the Keck Proto-Neptune project installed a seismic network consisting of 1 broadband and 7 short-period seismometers, installation of chemical/physical sensors and time-series samplers for chemistry and microbiology in the MEF and Clam Bed sites, collection of rocks, fluids, animals, and microbes. In May/June 2004, an NSF-sponsored al Atlantis/Alvin cruise recovered sulfide incubators installed in 2003, redeployed a sulfide incubator, mapped MEF and Mothra vent fields with high-resolution Imagenix sonar, sampled fluids from MEF, Mothra, and Clam Bed, recovered year-long time-series fluid and microbial samplers from MEF and Clam Bed, recovered and installed hot vent temperature-resistivity monitors, cleaned up the MEF and deployed new markers at major sulfide structures. In August 2004, there were two MBARI/Keck-sponsored cruises with R.V. al Western Flyer/ROV al Tiburon. The first cruise completed the seismic network with addition of two more broadband seismometers and serviced all 7 short-period seismometers. al Tiburon then performed microbial and chemical

  8. The Ethical Problems of Reserach : An empirical study of ethics in research practice

    OpenAIRE

    Colnerud, Gunnel

    2013-01-01

    Most accounts of the ethical problems facing researchers across a broad spectrum of research fields come from ethicists, ethics committees and specialists committed to the study of ethics in human research. In contrast, this study reports on the ethical questions that researchers, themselves, report facing in their everyday practice. Fifty-five Swedish researchers contributed 109 examples of ethical dilemmas, conflicts and problems in research. They were all researchers at the post-doctoral l...

  9. Crowdsourcing Disease Biomarker Discovery Research: The IP4IC Study.

    Science.gov (United States)

    Chancellor, Michael B; Bartolone, Sarah N; Veerecke, Andrew; Lamb, Laura E

    2018-05-01

    Biomarker discovery is limited by readily assessable, cost efficient human samples available in large numbers that represent the entire heterogeneity of the disease. We developed a novel, active participation crowdsourcing method to determine BP-RS (Bladder Permeability Defect Risk Score). It is based on noninvasive urinary cytokines to discriminate patients with interstitial cystitis/bladder pain syndrome who had Hunner lesions from controls and patients with interstitial cystitis/bladder pain syndrome but without Hunner lesions. We performed a national crowdsourcing study in cooperation with the Interstitial Cystitis Association. Patients answered demographic, symptom severity and urinary frequency questionnaires on a HIPAA (Health Insurance Portability and Accountability Act) compliant website. Urine samples were collected at home, stabilized with a preservative and sent to Beaumont Hospital for analysis. The expression of 3 urinary cytokines was used in a machine learning algorithm to develop BP-RS. The IP4IC study collected a total of 448 urine samples, representing 153 patients (147 females and 6 males) with interstitial cystitis/bladder pain syndrome, of whom 54 (50 females and 4 males) had Hunner lesions. A total of 159 female and 136 male controls also participated, who were age matched. A defined BP-RS was calculated to predict interstitial cystitis/bladder pain syndrome with Hunner lesions or a bladder permeability defect etiology with 89% validity. In this novel participation crowdsourcing study we obtained a large number of urine samples from 46 states, which were collected at home, shipped and stored at room temperature. Using a machine learning algorithm we developed BP-RS to quantify the risk of interstitial cystitis/bladder pain syndrome with Hunner lesions, which is indicative of a bladder permeability defect etiology. To our knowledge BP-RS is the first validated urine biomarker assay for interstitial cystitis/bladder pain syndrome and one of the

  10. Simulation Use in Paramedic Education Research (SUPER): A Descriptive Study.

    Science.gov (United States)

    McKenna, Kim D; Carhart, Elliot; Bercher, Daniel; Spain, Andrew; Todaro, John; Freel, Joann

    2015-01-01

    The purpose of this research was to characterize the use of simulation in initial paramedic education programs in order assist stakeholders' efforts to target educational initiatives and resources. This group sought to provide a snapshot of what simulation resources programs have or have access to and how they are used; faculty perceptions about simulation; whether program characteristics, resources, or faculty training influence simulation use; and if simulation resources are uniform for patients of all ages. This was a cross-sectional census survey of paramedic programs that were accredited or had a Letter of Review from the Committee on Accreditation of Educational Programs for the EMS Professions at the time of the study. The data were analyzed using descriptive statistics and chi-square analyses. Of the 638 surveys sent, 389 valid responses (61%) were analyzed. Paramedic programs reported they have or have access to a wide range of simulation resources (task trainers [100%], simple manikins [100%], intermediate manikins [99%], advanced/fully programmable manikins [91%], live simulated patients [83%], computer-based [71%], and virtual reality [19%]); however, they do not consistently use them, particularly advanced (71%), live simulated patients (66%), computer-based (games, scenarios) (31%), and virtual reality (4%). Simulation equipment (of any type) reportedly sits idle and unused in (31%) of programs. Lack of training was cited as the most common reason. Personnel support specific to simulation was available in 44% of programs. Programs reported using simulation to replace skills more frequently than to replace field or clinical hours. Simulation goals included assessment, critical thinking, and problem-solving most frequently, and patient and crew safety least often. Programs using advanced manikins report manufacturers as their primary means of training (87%) and that 19% of faculty had no training specific to those manikins. Many (78%) respondents felt

  11. A Bibliometric Study of Community Pharmacy-Based Research ...

    African Journals Online (AJOL)

    HP

    Research Activity in Middle Eastern Arab Countries: 2003 -. 2012. Waleed M ... International cooperation was highest with Malaysia (9.7 %) followed by ... Arab countries. Keywords: Community pharmacy, Middle East, Bibliometric review.

  12. CASE STUDY: Uzbekistan — Competition research improves services

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-12-22

    Dec 22, 2010 ... Small Grants Competition for Distribution Sector Research ... restrictive business practices in international money transfer services and find ways to .... through its own methodology on analyzing the financial services market [.

  13. Investigating Research Streams of Conjoint Analysis: A Bibliometric Study

    Directory of Open Access Journals (Sweden)

    Thorsten Teichert

    2010-05-01

    Full Text Available Conjoint analysis (CA is one of the most important methods for preference elicitation. In this paper we investigate the intellectual structure within the conjoint analytical research community. Analyses based on single papers provide a method-based overview of streams of conjoint research. By using novel bibliometric techniques in this field we complement findings of existing reviews. We use co-citation and factor analysis of the most cited articles in SSCI to identify the most important articles and research streams. Seven research streams are revealed which are visualized by means of multidimensional scaling. Tables and graphics reveal the disciplinary affiliations of contributors to CA, the special structure within the classes as well as links between them.

  14. Depression Research - The STAR*D Study - Relief in Hours?

    Science.gov (United States)

    Skip Navigation Bar Home Current Issue Past Issues Depression Research Past Issues / Summer 2007 Table of Contents ... multiple treatment options, two-thirds of those with depression can become symptom-free. Dr. A. John Rush ( ...

  15. Enacting the 'mobile' in tourism studies - Unraveling research practices

    DEFF Research Database (Denmark)

    Jensen, Martin Trandberg

    This chapter showcases how mobile methods are more than calibrated techniques awaiting application by tourism researchers, but productive in the enactment of the mobile (Law and Urry, 2004). Drawing upon recent findings deriving from a PhD course on mobility and mobile methods it reveals the conc......This chapter showcases how mobile methods are more than calibrated techniques awaiting application by tourism researchers, but productive in the enactment of the mobile (Law and Urry, 2004). Drawing upon recent findings deriving from a PhD course on mobility and mobile methods it reveals......, the engagements with methods are acknowledged to be always political and contextual, reminding us to avoid essentialist discussions regarding research methods. Finally, the chapter draws on recent fieldwork to extend developments in mobilities-oriented tourism research, by employing auto-ethnography to call...

  16. Researchers' preferences and attitudes on ethical aspects of genomics research: a comparative study between the USA and Spain.

    Science.gov (United States)

    Ruiz-Canela, M; Valle-Mansilla, J I; Sulmasy, D P

    2009-04-01

    The use of human samples in genomic research has increased ethical debate about informed consent (IC) requirements and the information that subjects should receive regarding the results of the research. However, there are no quantitative data regarding researchers' attitudes about these issues. We present the results of a survey of 104 US and 100 Spanish researchers who had published genomic epidemiology studies in 61 journals during 2006. Researchers preferred a broader IC than the IC they had actually obtained in their published papers. US authors were more likely than their Spanish colleagues to support obtaining a broad IC, covering either any future research project or any projects related to a group of diseases (67.6% vs 43%; adjusted OR = 4.84, 95% CI, 2.32 to 10.12). A slight majority of researchers (55.8%) supported informing participants about individual genomic results only if the reliability and clinical validity of the information had been established. Men were more likely than women to believe that patients should be informed of research results even if these conditions were not met (adjusted OR = 2.89, 95% CI = 1.46 to 5.72). This study provides evidence of a wide range of views among scientists regarding some controversial ethical issues related to genomic research, suggesting the need for more study, debate and education. In the interim, journals might consider including the investigators' policies regarding these ethical issues in the papers they publish in the field of genomic epidemiology.

  17. Exploring Reticence in Research Methods: The Experience of Studying Psychological Research Methods in Higher Education

    Science.gov (United States)

    Kingsley, Barbara E.; Robertson, Julia M.

    2017-01-01

    As a fundamental element of any psychology degree, the teaching and learning of research methods is repeatedly brought into sharp focus, and it is often regarded as a real challenge by undergraduate students. The reasons for this are complex, but frequently attributed to an aversion of maths. To gain a more detailed understanding of students'…

  18. A SHARED study-the benefits and costs of setting up a health research study involving lay co-researchers and how we overcame the challenges.

    Science.gov (United States)

    Mockford, Carole; Murray, Matt; Seers, Kate; Oyebode, Jan; Grant, Richard; Boex, Sue; Staniszewska, Sophie; Diment, Yvonne; Leach, Jim; Sharma, Uma; Clarke, Rosemary; Suleman, Rashida

    2016-01-01

    In the United Kingdom (UK), official bodies such as the Department of Health and research funders such as the National Institute for Health Research support and encourage lay involvement in all stages of research studies. The SHARED study has had substantial patient and public involvement (PPI) from developing the idea to dissemination. The aim of the study has been to develop recommendations led by service users for health and social care professionals to use at hospital discharge and in care planning for people living with memory loss and their carers. This article is about how the study started and the benefits, costs and challenges we encountered as the lead and lay co-researchers. Once we were successful with the grant application, we had to recruit and train the lay co-researchers and obtain various approvals before we could start the project. We had various support from funders, the Research Ethics Committee, lay members of Alzheimer's Society and from the lay co-researchers. However, we encountered some challenges with paying the lay co-researchers and with getting the approval for the co-researchers to interview staff on NHS premises. The challenges were overcome eventually but some aspects of the study changed because of this. We suggest that some changes could be made to the research system which would lead to greater inclusion of the lay co-researchers in research studies and would make the process more straightforward for the research team. Background Involving patients and the public in all stages of research has been the focus of the SHARED study. Patient and public involvement (PPI) is an important strategic priority for the Department of Health and funders such as the National Institute for Health Research. The aim of this paper is to describe the benefits, challenges and costs involved in setting up the research study with lay members as part of the research team. The study focused on developing service user-led recommendations for people with

  19. Missing Data Approaches in eHealth Research: Simulation Study and a Tutorial for Nonmathematically Inclined Researchers

    NARCIS (Netherlands)

    Blankers, Matthijs; Koeter, Maarten W. J.; Schippers, Gerard M.

    2010-01-01

    Background: Missing data is a common nuisance in eHealth research: it is hard to prevent and may invalidate research findings. Objective: In this paper several statistical approaches to data "missingness" are discussed and tested in a simulation study. Basic approaches (complete case analysis, mean

  20. Studies in Teaching. 1995 Research Digest. Papers Presented at the Annual Research Forum (Winston-Salem, North Carolina, December 1995).

    Science.gov (United States)

    McCoy, Leah P., Ed.

    This is a collection of papers reporting student research projects at the Annual Research Forum, Department of Education, Wake Forest University (North Carolina). They include: "Student Interest in Studying World History in Relation to Current Events" (Conan Arthur); "Perceptions of High School Student Athletes and Athletics"…

  1. Research

    African Journals Online (AJOL)

    abp

    2017-10-24

    Oct 24, 2017 ... Health Insurance Programme (TISHIP) in Nigeria: a case study of ... University Medical Centre staff responses showed a satisfactory scheme implementation. ... benefits. Previous studies revealed that students barely visit.

  2. Research

    African Journals Online (AJOL)

    abp

    2013-02-05

    Feb 5, 2013 ... experimental study (a pre and post-test interventional, one group), aimed at assessing the impact of health education on .... The study was quasi experimental using the ... using simple random sampling using a toss of coin.

  3. Research

    African Journals Online (AJOL)

    abp

    2017-12-05

    Dec 5, 2017 ... Methods: In this study, we used a qualitative multiple case study design ... For example, immunization should be taken when the child gets sick and a .... unimmunized children across the different regions had the opinion.

  4. Research

    African Journals Online (AJOL)

    raoul

    2012-04-16

    Apr 16, 2012 ... We chose to include male students in our study because previous studies have shown widespread lack of knowledge of the disease .... masculinity. ... The last few years have seen widespread use of internet social media.

  5. Research

    African Journals Online (AJOL)

    abp

    2016-05-13

    May 13, 2016 ... Results: The result of the study show that 21.6% thin, 4.8% were over weighted and 1.1% was obese, 32% were ... Studies from Asia [12-17] and few studies from African countries ..... Internet Journal of Nutrition and Wellness.

  6. Building Collaborative Research Opportunities into Study Abroad Programs: A Case Study from Panama

    Science.gov (United States)

    Solís, Patricia; Price, Marie; Adames de Newbill, María

    2015-01-01

    As universities increase their international study opportunities, enormous potential exists to create geography field courses that provide undergraduates and graduate students with primary research experience and intercultural collaboration. This paper draws from our experience leading a two-week collaborative field course in Panama. We outline…

  7. A Quantitative Study of the Internationalization of the Academics and Research Productivity: Case Study of China

    Science.gov (United States)

    Xian, Wu

    2015-01-01

    With the significant rise in China's economic strength, more students and scholars have returned to China recently. But there is limited literature examining academics with foreign degrees and their research productivity. Using the data of the Changing Academic Profession in Asia (APA) survey, which was exercised in 2012, this study expands the…

  8. Africanity and research: A case study in rural South Africa

    Directory of Open Access Journals (Sweden)

    Christina Landman

    2017-10-01

    Full Text Available In the first part of this article, Africanity as a concept within research methodology is exploredin the dialogical spaces between the binaries of racial identity and group identity, indigenousand traditional values, post-colonialism and post-racialism, blackness and African, as well aseliminativist and conservationalist. In the second part, the research carried out in twotownships in the eMakhazeni Local Municipality in Mpumalanga, South Africa’s most easternprovince, is described in terms of parameters and process. The townships involved areSakhelwe in Dullstroom-Emnotweni and Emthonjeni in Machadodorp-eNktokozweni. Theresearch focuses on interviews with young people between the ages of 18 and 24 on thepotential of faith-based organisations to assist them in moving from the ’margins‘ of society topositions of social cohesion. The third and main part of the article, is dedicated to lessonslearnt and experience acquired when research is carried out in a rural area from an Africanityperspective. This entails, inter alia (1 to be sensitive towards power relations in research; (2respecting indigenous values within group identities; (3 not predefining the youth, usingindigenous (and not European definitions of ‘agency’ and ‘marginalisation’; (4 to engage inobservation rather than interpretation; and (5 to decolonise the research process whenregarding interpretation as an act of colonisation.

  9. What Value Can Qualitative Research Add to Quantitative Research Design? An Example From an Adolescent Idiopathic Scoliosis Trial Feasibility Study.

    Science.gov (United States)

    Toye, Francine; Williamson, Esther; Williams, Mark A; Fairbank, Jeremy; Lamb, Sarah E

    2016-08-09

    Using an example of qualitative research embedded in a non-surgical feasibility trial, we explore the benefits of including qualitative research in trial design and reflect on epistemological challenges. We interviewed 18 trial participants and used methods of Interpretive Phenomenological Analysis. Our findings demonstrate that qualitative research can make a valuable contribution by allowing trial stakeholders to see things from alternative perspectives. Specifically, it can help to make specific recommendations for improved trial design, generate questions which contextualize findings, and also explore disease experience beyond the trial. To make the most out of qualitative research embedded in quantitative design it would be useful to (a) agree specific qualitative study aims that underpin research design, (b) understand the impact of differences in epistemological truth claims, (c) provide clear thematic interpretations for trial researchers to utilize, and (d) include qualitative findings that explore experience beyond the trial setting within the impact plan. © The Author(s) 2016.

  10. Association of learning styles with research self-efficacy: study of short-term research training program for medical students.

    Science.gov (United States)

    Dumbauld, Jill; Black, Michelle; Depp, Colin A; Daly, Rebecca; Curran, Maureen A; Winegarden, Babbi; Jeste, Dilip V

    2014-12-01

    With a growing need for developing future physician scientists, identifying characteristics of medical students who are likely to benefit from research training programs is important. This study assessed if specific learning styles of medical students, participating in federally funded short-term research training programs, were associated with research self-efficacy, a potential predictor of research career success. Seventy-five first-year medical students from 28 medical schools, selected to participate in two competitive NIH-supported summer programs for research training in aging, completed rating scales to evaluate learning styles at baseline, and research self-efficacy before and after training. We examined associations of individual learning styles (visual-verbal, sequential-global, sensing-intuitive, and active-reflective) with students' gender, ranking of medical school, and research self-efficacy. Research self-efficacy improved significantly following the training programs. Students with a verbal learning style reported significantly greater research self-efficacy at baseline, while visual, sequential, and intuitive learners demonstrated significantly greater increases in research self-efficacy from baseline to posttraining. No significant relationships were found between learning styles and students' gender or ranking of their medical school. Assessments of learning styles may provide useful information to guide future training endeavors aimed at developing the next generation of physician-scientists. © 2014 Wiley Periodicals, Inc.

  11. User study: information needs of contracting companies of market research

    Directory of Open Access Journals (Sweden)

    Frederico Cesar Mafra Pereira

    2018-01-01

    Full Text Available This paper has as main objective to understand why companies use market research as a source of information for their business, with a comparison between what they want to apply for a research and the effective use of the information received. The main methodological approach was based on the 'Model for identifying needs, seeking and use of information' (MAFRA PEREIRA, 2010, and from this approach has drawn up a script for conducting interviews with clients of research institute located in Belo Horizonte (MG. The results showed the applicability of the model, identifying information needs, gaps of information and the effective use of information in their respective organizational contexts; besides the methodological procedures for conducting and analyzing the results.

  12. Studies in Teaching: 2015 Research Digest. Action Research Projects Presented at Annual Research Forum (Winston-Salem, North Carolina, June 25, 2015)

    Science.gov (United States)

    McCoy, Leah P., Ed.

    2015-01-01

    This document presents the proceedings of the 20th Annual Research Forum held June 25, 2015, at Wake Forest University in Winston-Salem, North Carolina. Included are the following 21 action research papers: (1) History Lives! The Use of Simulations in a High School Social Studies Classroom (Lydia Adkins); (2) Using Francophone Music in the High…

  13. Automatic control study of the icing research tunnel refrigeration system

    Science.gov (United States)

    Kieffer, Arthur W.; Soeder, Ronald H.

    1991-01-01

    The Icing Research Tunnel (IRT) at the NASA Lewis Research Center is a subsonic, closed-return atmospheric tunnel. The tunnel includes a heat exchanger and a refrigeration plant to achieve the desired air temperature and a spray system to generate the type of icing conditions that would be encountered by aircraft. At the present time, the tunnel air temperature is controlled by manual adjustment of freon refrigerant flow control valves. An upgrade of this facility calls for these control valves to be adjusted by an automatic controller. The digital computer simulation of the IRT refrigeration plant and the automatic controller that was used in the simulation are discussed.

  14. Motivational factors for participation in biomedical research: evidence from a qualitative study of biomedical research participation in Blantyre District, Malawi.

    Science.gov (United States)

    Mfutso-Bengo, Joseph; Manda-Taylor, Lucinda; Masiye, Francis

    2015-02-01

    Obtaining effective informed consent from research participants is a prerequisite to the conduct of an ethically sound research. Yet it is believed that obtaining quality informed consent is generally difficult in settings with low socioeconomic status. This is so because of the alleged undue inducements and therapeutic misconception among participants. However, there is a dearth of data on factors that motivate research participants to take part in research. Hence, this study was aimed at filling this gap in the Malawian context. We conducted 18 focus group discussions with community members in urban and rural communities of Blantyre in Malawi. Most participants reported that they accepted the invitation to participate in research because of better quality treatment during study also known as ancillary care, monetary and material incentives given to participants, and thorough medical diagnosis. © The Author(s) 2014.

  15. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-10-14

    Oct 14, 2015 ... Abstract. Introduction: Studies have shown high initial mortality in Antiretroviral Therapy (ART) programs from resource-limited settings. However, there is dearth of evidence on treatment outcomes and associated determinant factors in public hospitals. Therefore, the objective of this study is to assess.

  16. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-08-20

    Aug 20, 2015 ... Ethiopia Demographic Health survey (EDHS) and 2012 country report the ... Ethiopia and Haiti revealed that the prevalence of treatment failure ... Study population. The study population was all HIV infected patients with age ≥15yrs who started first line ART in St. Luke and Tulu Bolo Hospitals since.

  17. Research

    African Journals Online (AJOL)

    retention in a newly established medical school in Tanzania. Previous studies found that small salaries, limited career options, heavy teaching loads, growing enrolment and the absence of equipment and support staff were the main barriers to retain faculty staff.[11] These factors have been confirmed by the study at CUHAS ...

  18. Research

    African Journals Online (AJOL)

    ebutamanya

    2016-04-22

    Apr 22, 2016 ... Abstract. Introduction: The aim of this study was to investigate the relationship between HbA1c and carotid intima-media thickness (cIMT) which is noninvasive marker of atherosclerosis in type 2 diabetic patients. Methods: 81 type 2 diabetic patients were enrolled in this study. Demographic, clinical and ...

  19. Research

    African Journals Online (AJOL)

    abp

    2017-09-29

    Sep 29, 2017 ... admitted to a tertiary level hospital: a retrospective cohort study. Marwa Osman1 .... outside the study period and patients with end stage renal disease ... specially designed and pre-tested questionnaire. .... Susantitaphong et al. the world incidence of AKI among hospitalized ..... Uncertain classification.

  20. Research

    African Journals Online (AJOL)

    abp

    Abstract. Introduction: The aim of the study is to compare efficacy of IvIg versus PE in treatment of mechanically ventilation adults with GBS in intensive care unit. Methods: It is a prospective, non randomized study, realized in a medical ICU from 2006 to 2010. We included all patients with GBS who required mechanical ...

  1. Research

    African Journals Online (AJOL)

    [2,3] The definition of a rural-origin student. (ROS) has come under some debate, but for the purpose of this study ... The language of teaching and learning for students not studying in their mother tongue has been seen to pose problems ... trend towards e-learning. Students not previously exposed to this level of technology ...

  2. Research

    African Journals Online (AJOL)

    raoul

    13 févr. 2012 ... la violence conjugale envers les femmes dans la capitale malgache. ELVICA a interrogé ..... Jess F. Risk factors for injury to women from domestic violence against women. N Engl J Med. ... Studies in Family Planning. 2001; 32(1) ... practices: findings of a South African cross-sectional study. Soc Sci Med.

  3. Research

    African Journals Online (AJOL)

    ebutamanya

    2016-03-09

    Mar 9, 2016 ... inadequately control asthma could help in strategies to improve asthma control. This study ... terms of pathophysiology and management of asthma, studies show that this ... increases the use of health care services [12, 13], and therefore ..... 25. de Vries MP, van den Bemt L, Lince S, Muris JW, Thoonen BP,.

  4. Research

    African Journals Online (AJOL)

    abp

    2017-11-22

    Nov 22, 2017 ... gradually into the baby's diet, first to complement breast feeding and progressively to replace it and get the child used to adult diet. This study aimed to assess ... suboptimal. It was also evident from this study that complementary and weaning practices were influenced by maternal and house-hold factors. It.

  5. Research

    African Journals Online (AJOL)

    abp

    2016-07-12

    Jul 12, 2016 ... preterm birth, low birth weight and /or preterm low birth weight and periodontitis. Of the selected studies, 9 implied an association between periodontal disease and increased risk of preterm birth, low birth weight and /or preterm low birth weight outcome (ORs ranging from 2.04 to. 4.19) and only one study ...

  6. Recent studies of laser science in paintings conservation and research.

    Science.gov (United States)

    Pouli, Paraskevi; Selimis, Alexandros; Georgiou, Savas; Fotakis, Costas

    2010-06-15

    The removal of aged and deteriorated molecular overlayers from the surface of paintings is a delicate and critical intervention in Cultural Heritage (CH) conservation. This irreversible action gets particularly complicated given the multitude of materials that may be present within a painted work of art (often in ultrathin layers or traces), as well as the exceptional sensitivity of the original surfaces to environmental conditions such as heat, light, and so on. Lasers hold an important role among the available cleaning methodologies, as they enable high control and accuracy, material selectivity, and immediate feedback. Still, prior to their implementation, it is imperative to optimize the cleaning parameters, so to ensure that any potential implications to the remaining materials are minimal and well understood. Toward this aim, research at IESL-FORTH is focused on both refining and continuously updating the laser-cleaning protocols (by introducing novel laser technologies into the field, i.e., ultrashort laser pulses), as well as on investigating and studying the nature and extent of laser-induced physicochemical alterations to the involved materials. In this Account, extended work for the understanding of ultraviolet (UV) laser ablation of polymers is presented. Emphasis is placed on the use of model systems (polymers doped with chromophores of known photochemistry) to examine the in-depth laser-induced modifications at the processed surfaces and thus to illustrate the dependence of their nature and extent on laser parameters and material properties. Furthermore, studies for the potential use of femtosecond UV pulses to overcome certain limitations involved with the nanosecond ablation of molecular overlayers from CH surfaces are highlighted. In particular, it is demonstrated that in the femtosecond regime any chemical modifications are, qualitatively and quantitatively, highly defined, limited and nearly independent of the material properties, such as the

  7. Feasibility studies on future phycological research in polar regions

    Czech Academy of Sciences Publication Activity Database

    Elster, Josef; Svoboda, J.; Ohtani, S.; Kanda, H.

    2002-01-01

    Roč. 15, - (2002), s. 114-122 ISSN 0914-5613 R&D Projects: GA AV ČR IAA6005002; GA ČR GA206/93/1177 Institutional research plan: CEZ:AV0Z6005908; CEZ:MSM 123100004 Keywords : Cyanobacteria * algae * primary succession * primary production Subject RIV: EA - Cell Biology

  8. ADVANCED COMPOSITES TECHNOLOGY CASE STUDY AT NASA LANGLEY RESEARCH CENTER

    Science.gov (United States)

    This report summarizes work conducted at the National Aeronautics and Space Administration's Langley Research Center (NASA-LaRC) in Hampton, VA, under the U.S. Environmental Protection Agency’s (EPA) Waste Reduction Evaluations at Federal Sites (WREAFS) Program. Support for...

  9. Research Article Genome-wide association study for economic traits ...

    Indian Academy of Sciences (India)

    Aiqiang Lin

    kept in 4 °C. The PCR products were run on an 8% polyacrylamide gel electrophoresis. Fragments. 103 ..... research reveals a conserved role of phosphorylation of the N terminus of BORA for Plk1. 229 ..... J. Food Compos Anal. 33, 1-5. 359.

  10. Literature study of source term research for PWRs

    Energy Technology Data Exchange (ETDEWEB)

    Sponton, L.L.; NiIsson, Lars

    2001-04-01

    A literature survey has been carried out in support of ongoing source term calculations with the MELCOR code of some severe accident scenarios for the Swedish Ringhals 2 pressurised water reactor (PWR). The research in the field of severe accidents in power reactors and the source term for subsequent release of radioisotopes was intensified after the Harrisburg accident and has produced a large amount of reports and papers. This survey was therefore limited to research concerning PWR type of reactors and with emphasis on papers related to MELCOR code development. A background is given, relating to some historic documents, and then more recent research after 1990 is reviewed. Of special interest is the ongoing PMbus-programme which is creating new and important results of benefit to the code development and validation of, among others, the MELCOR code. It is concluded that source term calculations involve simulation of many interacting complex physical phenomena, which result in large uncertainties The research has, however, over the years led to considerable improvements Thus has the uncertainty in source term predictions been reduced one to two orders of magnitude from the simpler codes in the early 1980-s to the more realistic codes of today, like MELCOR.

  11. A Bibliometric Study of Community Pharmacy-Based Research ...

    African Journals Online (AJOL)

    2003-01-01

    Purpose: To analyze community pharmacy based research in Arab countries. Methods: Comprehensive review of the literature indexed by Scopus was conducted. Data from Jan 01, 2003 till December 31, 2013 was searched for documents with specific words pertaining to “community pharmacy” in any one of the 13 Middle ...

  12. TEACHING SIMULATION: AN ACTION RESEARCH STUDY ON MRP CONTENT

    Directory of Open Access Journals (Sweden)

    Cristiano Henrique Antonelli da Veiga

    2014-06-01

    the presentation of the scientific content and the second, mediated experiences. The  development of the proposal was investigated using action research methodology through an exercise prepared by the teacher of the subject. Upon completion of the didactic activity, it was found that students improved their understanding of the concepts and logic of calculation and operationalization in mrp I.

  13. Research Review of the Institute of African Studies: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  14. Reporting research methods of empirical studies | Korb | Journal of ...

    African Journals Online (AJOL)

    Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL · News. OTHER RESOURCES.

  15. Summary of Military Manpower Market Research Studies: A Technical Report

    Science.gov (United States)

    1991-09-01

    significant implications for recruiting and advertising managers on programs offered, marketing and advertising strategies, advertising messages, and the...operation was adopted. Over the past 10 years, military recruiting has become a leader in marketing and advertising ’ research. Although the aii-ection

  16. Dalit entrepreneurship research study: Insight on 25% of the Indian ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    It will survey 12,000 Dalit entrepreneurs in 14 states, collecting data from individual ... IDRC invests in research and knowledge to empower women in India ... to address climate change-related challenges in India, including heat stress, water ...

  17. Educational Choice Regarding Technical Education: Research with Case Study

    Science.gov (United States)

    Kacerauskas, Tomas; Šaparauskas, Jonas

    2017-01-01

    In first part, the models, theories, mechanisms and presumptions, as well as the ideas of educational choice discourse have been scrutinized. In the second part, the survey on educational choice at Vilnius Gediminas Technical University, Lithuania has been presented. The methodology used in this research is a survey of respondents and survey…

  18. Research Review of the Institute of African Studies: Submissions

    African Journals Online (AJOL)

    They should be accompanied by a brief biographical note giving the author's name in the form it shouldappear in print, current academic or professional position and field of research interest. Please see theinside back cover of this issue for detailed ... for publication in another journal or book. Plagiarism must be avoided.

  19. Literature study of source term research for PWRs

    International Nuclear Information System (INIS)

    Sponton, L.L.; NiIsson, Lars

    2001-04-01

    A literature survey has been carried out in support of ongoing source term calculations with the MELCOR code of some severe accident scenarios for the Swedish Ringhals 2 pressurised water reactor (PWR). The research in the field of severe accidents in power reactors and the source term for subsequent release of radioisotopes was intensified after the Harrisburg accident and has produced a large amount of reports and papers. This survey was therefore limited to research concerning PWR type of reactors and with emphasis on papers related to MELCOR code development. A background is given, relating to some historic documents, and then more recent research after 1990 is reviewed. Of special interest is the ongoing PMbus-programme which is creating new and important results of benefit to the code development and validation of, among others, the MELCOR code. It is concluded that source term calculations involve simulation of many interacting complex physical phenomena, which result in large uncertainties The research has, however, over the years led to considerable improvements Thus has the uncertainty in source term predictions been reduced one to two orders of magnitude from the simpler codes in the early 1980-s to the more realistic codes of today, like MELCOR

  20. Mentoring: A Review of Early Career Researcher Studies

    Science.gov (United States)

    Boeren, Ellen; Lokhtina-Antoniou, Irina; Sakurai, Yusuke; Herman, Chaya; McAlpine, Lynn

    2015-01-01

    This paper reviews 23 journal articles on "mentoring" in the context of Early Career Researchers, defined as those in academia with less than 10 years of experience from the start of their PhD. Achieving a better understanding of mentoring is important since within the higher education context new dynamics have created expectations…

  1. Doing Research Together: A Study on the Views of Advisors with Intellectual Disabilities and Non-Disabled Researchers Collaborating in Research.

    Science.gov (United States)

    Puyalto, Carol; Pallisera, Maria; Fullana, Judit; Vilà, Montserrat

    2016-03-01

    Despite an increase in inclusive studies in recent years, research on the views of the people with and without disabilities who have participated in these studies is scarce. The aim of this study was to explore the perceptions and views of advisors with intellectual disabilities and non-disabled researchers who collaborated together on a joint project to study transition to adulthood. Two questionnaires were devised, one for advisors and one for researchers; two focus groups were held with people with intellectual disabilities, three focus groups with researchers, and one focus group with all participants together. Thematic analysis was used for the data analysis. The advisors valued this experience as an opportunity to learn new skills, freely express themselves on matters that affect them, and engage in a socially valued activity. The researchers considered that the participation of people with intellectual disabilities contributed to improving the quality of the research. The study provides a better understanding of inclusive research processes by taking into account participants' views. © 2015 John Wiley & Sons Ltd.

  2. Randomly auditing research labs could be an affordable way to improve research quality: A simulation study.

    Science.gov (United States)

    Barnett, Adrian G; Zardo, Pauline; Graves, Nicholas

    2018-01-01

    The "publish or perish" incentive drives many researchers to increase the quantity of their papers at the cost of quality. Lowering quality increases the number of false positive errors which is a key cause of the reproducibility crisis. We adapted a previously published simulation of the research world where labs that produce many papers are more likely to have "child" labs that inherit their characteristics. This selection creates a competitive spiral that favours quantity over quality. To try to halt the competitive spiral we added random audits that could detect and remove labs with a high proportion of false positives, and also improved the behaviour of "child" and "parent" labs who increased their effort and so lowered their probability of making a false positive error. Without auditing, only 0.2% of simulations did not experience the competitive spiral, defined by a convergence to the highest possible false positive probability. Auditing 1.35% of papers avoided the competitive spiral in 71% of simulations, and auditing 1.94% of papers in 95% of simulations. Audits worked best when they were only applied to established labs with 50 or more papers compared with labs with 25 or more papers. Adding a ±20% random error to the number of false positives to simulate peer reviewer error did not reduce the audits' efficacy. The main benefit of the audits was via the increase in effort in "child" and "parent" labs. Audits improved the literature by reducing the number of false positives from 30.2 per 100 papers to 12.3 per 100 papers. Auditing 1.94% of papers would cost an estimated $15.9 million per year if applied to papers produced by National Institutes of Health funding. Our simulation greatly simplifies the research world and there are many unanswered questions about if and how audits would work that can only be addressed by a trial of an audit.

  3. Case study: An ethics case study of HIV prevention research on Facebook: the Just/Us study.

    Science.gov (United States)

    Bull, Sheana S; Breslin, Lindsey T; Wright, Erin E; Black, Sandra R; Levine, Deborah; Santelli, John S

    2011-01-01

    To consider issues related to research with youth on social networking sites online. Description of the data collection process from 1,588 participants in a randomized controlled trial testing the efficacy of HIV prevention education delivered on Facebook. Using respondent-driven sampling, staff-recruited participants are encouraged to recruit up to three friends to enroll in the study. Researchers should (a) consider whether an online social networking site is an appropriate place to implement a research study; (b) offer opportunities to review informed consent documents at multiple times and in multiple locations throughout the study; and (c) collect data outside the social networking site and store it behind secure firewalls to ensure it will not be accessible to any person on the social networking site. Online social networks are growing in popularity. Conducting research on social media sites requires deliberate attention to consent, confidentiality, and security.

  4. Research

    African Journals Online (AJOL)

    cqq1a

    2010-08-29

    Aug 29, 2010 ... by SLE Disease Activity Index (SLEDAI), and quality of life was measured by ... support to SLE patients beside rapid meticulous control of disease activity. ..... Table 2: Clinical and laboratory findings in studied SLE population.

  5. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-06-30

    Jun 30, 2015 ... &Corresponding author: Musa Thomas Samdi, National Ear Care Center Kaduna Nigeria, ... Ear pain as only presenting symptom was the major complain found in this study accounting for 68(51.1%). .... Authors' contributions.

  6. Research

    African Journals Online (AJOL)

    abp

    2013-08-08

    Aug 8, 2013 ... Preconception genetic screening and counselling should be the main focus of .... important variable that influences the acceptability, practice and success of ... attention. Study done among health care workers and medical.

  7. Research

    African Journals Online (AJOL)

    abp

    2017-11-06

    Nov 6, 2017 ... Odumegwu Ojukwu University Teaching Hospital, Awka, Nigeria. &Corresponding .... Overall, in this study, anemia was defined as Hb ≤ 12.0g/dl. Desirable ... nutritional or other factors that might account for this difference. In.

  8. Research

    African Journals Online (AJOL)

    abp

    2017-10-06

    Oct 6, 2017 ... the importance of early reporting to the hospital for early diagnosis and treatment. There is also ... multivariable logistic regression analysis. Results. From this study ..... weight loss: business Briefing. US Oncology Review.

  9. Research

    African Journals Online (AJOL)

    abp

    2015-03-06

    Mar 6, 2015 ... Introduction: Several studies in Sub- Saharan Africa have documented high and ... Methods: A Descriptive cross sectional survey was employed and three hundred twenty ... In addition, unwanted pregnancy among female.

  10. Research

    African Journals Online (AJOL)

    ebutamanya

    2016-04-22

    Apr 22, 2016 ... Papulosquamous disorders, Infectious disorders, Connective tissue diseases, Bullous disorders, ... surgical pathology specimen received within the study period. The modal age ... enable appropriate management. ... basic clinical data including age, gender were noted. ... Confidentiality of the identity of the.

  11. Research

    African Journals Online (AJOL)

    ebutamanya

    2016-03-03

    Mar 3, 2016 ... The profile of patients with obstructive uropathy in Cameroon: case of the Douala. General ... Symptoms at presentation: asthenia (57%), anorexia. (55%), loin .... This study on the clinical profile and outcome of patients with.

  12. Research

    African Journals Online (AJOL)

    raoul

    2011-03-11

    Mar 11, 2011 ... The prevalence and pattern of HPV-16 immunostaining in uterine cervical carcinomas .... irregular vaginal bleeding or post coital bleeding. .... Dr MR and Dr AB equally contributed to the study, both are pathologists. Dr. AB ...

  13. Research

    African Journals Online (AJOL)

    abp

    2013-07-23

    Jul 23, 2013 ... 1Department of Family Medicine, Faculty of Medicine, Suez Canal University, Egypt. &Corresponding ... Results: Hundred family physicians were included in the study. They were previously ..... organization. There was a ...

  14. Research

    African Journals Online (AJOL)

    abp

    2014-01-31

    Jan 31, 2014 ... Hypercholesterolemia correlated significantly with age and sex. Conclusion: Our study showed a ... work is properly cited. Pan African Medical .... to sex. References. 1. Facing the facts: the impact of chronic disease in Africa.

  15. Research

    African Journals Online (AJOL)

    Method. A mixed-method study design was used that collected qualitative data through a review of curriculum documents ... quantitative data from 109 final-year students. .... A mixed methods approach was used in this descriptive, analytical.

  16. Research

    African Journals Online (AJOL)

    abp

    2015-01-16

    Jan 16, 2015 ... expressed in Prostatic adenocarcinoma and squamous cell carcinoma of the prostate while Ck8 and Ki67 ... Ki67 antigen is a useful proliferation marker [13]. ... This study therefore examined the individual expression and the.

  17. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-08-27

    Aug 27, 2015 ... Exclusive breastfeeding and HIV/AIDS: a crossectional survey of mothers attending prevention of ... Methods: A hospital-based cross-sectional study was conducted among 600 HIV-positive using a ... Despite the benefits.

  18. Research

    African Journals Online (AJOL)

    abp

    2017-10-04

    Oct 4, 2017 ... Key words: Exclusive breastfeeding, infant diarrhoea, immunization status, infant care, ... This study was designed to determine the prevalence and identify determinants of ..... diarrhoea among infants will benefit greatly from.

  19. Research

    African Journals Online (AJOL)

    abp

    2013-10-29

    Oct 29, 2013 ... in the tropical and sub-tropical regions around the world [1]. ... infections worldwide, with 50-100 million dengue fever (DF) infections and ..... Another study in Brazil also demonstrated that participants with antibodies to.

  20. Research

    African Journals Online (AJOL)

    abp

    2016-03-25

    Mar 25, 2016 ... Key words: Health insurance, antenatal care, insurance uptake ... Information generated from this study if utilized will bring a better understanding ..... the questions were prone to recall bias. ... cleared picture of the situation.

  1. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-01-20

    Jan 20, 2015 ... infection in a cross-sectional study of 79 consecutive patients with chronic antral ... during upper gastrointestinal endoscopy for pathology and fixed in formol 10% .... bleeding, with active bleeding during endoscopy, those on.

  2. Research

    African Journals Online (AJOL)

    abp

    2013-10-28

    Saharan Africa, including Burkina Faso. However, few published data are available on the prevalence of syphilis in the population. This study had two main objectives: to determine the seroprevalence of syphilis in a cohort of ...

  3. Research

    African Journals Online (AJOL)

    abp

    2016-07-14

    Jul 14, 2016 ... 9.44), government employment by occupation (AOR=2.23, 95%CI: ... Conclusion: Male involvement in PMTCT programme was low in the study area. ..... Gondar woreda health offices for their assistance and permission to.

  4. Research

    African Journals Online (AJOL)

    career planning, work-life balance, personal problems, and study skills with ... It was important to investigate the students' perceptions of the appraisal process, as an .... as I have no family members in the medical profession to discuss future.

  5. Research

    African Journals Online (AJOL)

    abp

    2017-09-12

    Sep 12, 2017 ... from porin or penicillin-binding protein modifications [5]. The aim of ... Methods. Bacterial isolates: This study analyzed 27 unduplicated .... including PFGE of chromosomal DNA restriction fragments have been used to ...

  6. Research

    African Journals Online (AJOL)

    abp

    2015-11-24

    Nov 24, 2015 ... AGR was the dependable variable and included two diabetic categories; diabetes and ..... (232/334) had never consumed alcohol in their life time. Over half .... diagnosing type 2 diabetes mellitus: a community-based study.

  7. Research

    African Journals Online (AJOL)

    abp

    2014-03-19

    Mar 19, 2014 ... management among teaching hospital staff in south east Nigeria: an intervention study ... Published in partnership with the African Field Epidemiology Network ... and specifically the infection prevention and control team in the.

  8. Visceral fat dominant distribution in male type 2 diabetic patients is closely related to hepatic insulin resistance, irrespective of body type

    Directory of Open Access Journals (Sweden)

    Miyazaki Yoshinori

    2009-08-01

    Full Text Available Abstract Background All previous studies that investigated the association between abdominal fat distribution and insulin resistance evaluated subcutaneous and visceral fat area and/or volume, but these values were not related to the body type of each subject. In the present study we have examined the association between abdominal fat distribution and peripheral (muscle/hepatic sensitivity to insulin using the visceral to abdominal subcutaneous fat area ratio (VF/SF ratio in male patients with type 2 diabetes mellitus. This ratio defines the predominancy of visceral or subcutaneous abdominal adiposity, independent of the body type of each individual. Methods Thirty-six type 2 diabetic male patients underwent a euglycemic insulin clamp (insulin infusion rate = 40 mU/m2·min with 3-3H-glucose to measure insulin-mediated total body (primarily reflects muscle glucose disposal (TGD and suppression of endogenous (primarily reflects liver glucose production (EGP in response to a physiologic increase in plasma insulin concentration. Abdominal subcutaneous (SF and intraabdominal visceral fat (VF areas were quantitated with magnetic resonance imaging (MRI at the level of L4–5. Results TGD and TGD divided by steady state plasma insulin concentration during the insulin clamp (TGD/SSPI correlated inversely with body mass index (BMI, total fat mass (FM measured by 3H2O, SF and VF areas, while VF/SF ratio displayed no significant relationship with TGD or TGD/SSPI. In contrast, EGP and the product of EGP and SSPI during the insulin clamp (an index hepatic insulin resistance correlated positively with VF/SF ratio, but not with BMI, FM, VF or SF. Conclusion We conclude that, independent of the individual's body type, visceral fat dominant accumulation as opposed to subcutaneous fat accumulation is associated with hepatic insulin resistance, whereas peripheral (muscle insulin resistance is more closely related to general obesity (i.e. higher BMI and total FM

  9. Study on the Export Strategies for Research Reactors

    International Nuclear Information System (INIS)

    Oh, S. K.; Lee, Y. J.; Ham, T. K.; Hong, S. T.; Kim, J. H.

    2008-12-01

    Key strategic considerations taken into account should be based on understanding in the forecasts of demand and supply balance as well as the missions of research reactor for customers. For timely arrival at the competition, it may be advantageous to categorize the potential customers into 3 groups, the developed, the developing and the underdeveloped countries in respect of nuclear technology, and to be ready for the group-wise reference designs of the key reactor systems. Customizing the design to specific owner's requirements can advance from one of these reference designs when competition starts. To mobilize this approach effectively, it is useful to establish an integral project and technology management system earlier. This system will function as an important success factor for international research reactor business, because it makes easy to accommodate customer requirements and to achieve the design-to-cost.

  10. Charged particle beam propagation studies at the Naval Research Laboratory

    International Nuclear Information System (INIS)

    Meger, R.A.; Hubbard, R.F.; Antoniades, J.A.; Fernsler, R.F.; Lampe, M.; Murphy, D.P.; Myers, M.C.; Pechacek, R.E.; Peyser, T.A.; Santos, J.; Slinker, S.P.

    1993-01-01

    The Plasma Physics Division of the Naval Research Laboratory has been performing research into the propagation of high current electron beams for 20 years. Recent efforts have focused on the stabilization of the resistive hose instability. Experiments have utilized the SuperIBEX e-beam generator (5-MeV, 100-kA, 40-ns pulse) and a 2-m diameter, 5-m long propagation chamber. Full density air propagation experiments have successfully demonstrated techniques to control the hose instability allowing stable 5-m transport of 1-2 cm radius, 10-20 kA total current beams. Analytic theory and particle simulations have been used to both guide and interpret the experimental results. This paper will provide background on the program and summarize the achievements of the NRL propagation program up to this point. Further details can be found in other papers presented in this conference

  11. Industry-identified combustion research needs: Special study

    Energy Technology Data Exchange (ETDEWEB)

    Keller, J.G.; Soelberg, N.R.; Kessinger, G.F.

    1995-11-01

    This report discusses the development and demonstration of innovative combustion technologies that improve energy conservation and environmental practices in the US industrial sector. The report includes recommendations by industry on R&D needed to resolve current combustion-related problems. Both fundamental and applied R&D needs are presented. The report assesses combustion needs and suggests research ideas for seven major industries, which consume about 78% of all energy used by industry. Included are the glass, pulp and paper, refinery, steel, metal casting, chemicals, and aluminum industries. Information has been collected from manufacturers, industrial operators, trade organizations, and various funding organizations and has been supplemented with expertise at the Idaho National Engineering Laboratory to develop a list of suggested research and development needed for each of the seven industries.

  12. New Research Methods Developed for Studying Diabetic Foot Ulceration

    Science.gov (United States)

    1998-01-01

    Dr. Brian Davis, one of the Cleveland Clinic Foundation's researchers, has been investigating the risk factors related to diabetic foot ulceration, a problem that accounts for 20 percent of all hospital admissions for diabetic patients. He had developed a sensor pad to measure the friction and pressure forces under a person's foot when walking. As part of NASA Lewis Research Center's Space Act Agreement with the Cleveland Clinic Foundation, Dr. Davis requested Lewis' assistance in visualizing the data from the sensor pad. As a result, Lewis' Interactive Data Display System (IDDS) was installed at the Cleveland Clinic. This computer graphics program is normally used to visualize the flow of air through aircraft turbine engines, producing color two- and three-dimensional images.

  13. Study on the Export Strategies for Research Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Oh, S. K.; Lee, Y. J.; Ham, T. K.; Hong, S. T.; Kim, J. H. [Ajou University, Suwon (Korea, Republic of)

    2008-12-15

    Key strategic considerations taken into account should be based on understanding in the forecasts of demand and supply balance as well as the missions of research reactor for customers. For timely arrival at the competition, it may be advantageous to categorize the potential customers into 3 groups, the developed, the developing and the underdeveloped countries in respect of nuclear technology, and to be ready for the group-wise reference designs of the key reactor systems. Customizing the design to specific owner's requirements can advance from one of these reference designs when competition starts. To mobilize this approach effectively, it is useful to establish an integral project and technology management system earlier. This system will function as an important success factor for international research reactor business, because it makes easy to accommodate customer requirements and to achieve the design-to-cost.

  14. A Case Study of Teaching Marketing Research Using Client-Sponsored Projects: Method, Challenges, and Benefits

    Science.gov (United States)

    Bove, Liliana L.; Davies, W. Martin

    2009-01-01

    This case study outlines the use of client-sponsored research projects in a quantitative postgraduate marketing research subject conducted in a 12-week semester in a research-intensive Australian university. The case study attempts to address the dearth of recent literature on client-sponsored research projects in the discipline of marketing.…

  15. From research to policy: The White Cap Wilderness Fire Study

    Science.gov (United States)

    Diane Smith

    2014-01-01

    On August 18, 1972, an aerial patrol reported a snag burning deep in the Selway-Bitterroot Wilderness in Idaho. Bob Mutch, then a young research forester, traveled to the site the following day for an on-the-ground assessment. It was, Mutch later recalled, a little "nothing fire" that posed no threat. And he was right. Growing to only 24 feet by 24...

  16. Occupational health research priorities in Malaysia: a Delphi study

    OpenAIRE

    Sadhra, S; Beach, J; Aw, T; Sheikh-Ahmed, K

    2001-01-01

    OBJECTIVES—As part of a consultancy project on occupational health, the Delphi method was used to identify research priorities in occupational health in Malaysia.
METHODS—Participation was sought from government ministries, industry, and professional organisations, and university departments with an interest in occupational and public health. Two rounds of questionnaires resulted in a final list of priorities, with noticeable differences between participants depending on whether they worked i...

  17. Audiological and surgical evidence for the presence of a third window effect for the conductive hearing loss in DFNX2 deafness irrespective of types of mutations.

    Science.gov (United States)

    Choi, Byung Yoon; An, Yong-Hwi; Park, Joo Hyun; Jang, Jeong Hun; Chung, Hyun Chung; Kim, Ah-Reum; Lee, Jun Ho; Kim, Chong-Sun; Oh, Seung Ha; Chang, Sun O

    2013-11-01

    The objective of this study was to clarify the cause of the air-bone gap in incomplete partition (IP) type III cases according to the POU3F4 gene (DFNX2) mutation type. A retrospective analysis of patient medical records was done in a tertiary referral medical center. Five IP type III patients proved to be carrying a mutation in or affecting POU3F4. The hearing and the middle ear status at either exploratory tympanotomy or cochlear implantation from these DFNX2 cases was reviewed. Four of five unrelated IP type III patients harbored a point mutation of POU3F4 and the fifth patient carried a large genomic deletion upstream to POU3F4. Two of the four DFNX2 patients carrying a point mutation had moderate to severe mixed hearing loss with a substantial amount of air-bone gap. These patients underwent exploratory tympanotomy to identify the cause of their hearing loss. The other three patients, including one carrying a large deletion, had profound hearing loss at presentation and received a cochlear implant. In the exploratory tympanotomy group with a substantial amount of air-bone gap and a point mutation (n = 2), one patient had a perfect ossicular chain with normal mobility, a positive ipsilateral stapedial reflex, and a positive round window reflex. In the cochlear implantation group (n = 3), we found a stapes with normal mobility and a positive round window reflex in one patient who harbored a large genomic deletion upstream to POU3F4. We concluded that the probable presence of the third window effect is not limited to the particular type of POU3F4 mutation.

  18. Solar Energy Evolution and Diffusion Studies Webinars | Solar Research |

    Science.gov (United States)

    NREL Studies Webinars Solar Energy Evolution and Diffusion Studies Webinars These webinars . Department of Energy's Solar Energy Evolution and Diffusion Studies (SEEDS) program. SEEDS 2017-2019 Study Residential Solar July 20, 2017 Presenters: Kiran Lakkaraju, Sandia National Laboratories Yevgeniy Vorobeychik

  19. Research on the phenomenon of graphitization. Crystallographic study - Study of bromine sorption

    International Nuclear Information System (INIS)

    Maire, Jacques

    1967-01-01

    This research thesis reports the study of the mechanism of graphitization of carbon by using X-ray diffraction analysis and the physical and chemical study of lamellar reactions between carbon and bromine. The author first presents generalities and results of preliminary studies (meaning of graphitization, presentation of the various carbon groups and classes), and then reports the study of the graphitization of compact carbons (soft carbons). More precisely, he reports the crystallographic study of partially graphitized carbons: methods and principles, experimental results and their analysis, discussion of the graphitization mechanism. In the next part, the author reports the study of bromine sorption on carbons: experimental method, isotherms of a natural graphite and of a graphitized carbon, structure of carbon-bromine complexes, isotherms of graphitizable carbons and of all other carbons, distribution of bromine layers in partially graphitized carbons, bromine sorption and Fermi level

  20. LPS-Induced Low-Grade Inflammation Increases Hypothalamic JNK Expression and Causes Central Insulin Resistance Irrespective of Body Weight Changes.

    Science.gov (United States)

    Rorato, Rodrigo; Borges, Beatriz de Carvalho; Uchoa, Ernane Torres; Antunes-Rodrigues, José; Elias, Carol Fuzeti; Elias, Lucila Leico Kagohara

    2017-07-04

    Metabolic endotoxemia contributes to low-grade inflammation in obesity, which causes insulin resistance due to the activation of intracellular proinflammatory pathways, such as the c-Jun N-terminal Kinase (JNK) cascade in the hypothalamus and other tissues. However, it remains unclear whether the proinflammatory process precedes insulin resistance or it appears because of the development of obesity. Hypothalamic low-grade inflammation was induced by prolonged lipopolysaccharide (LPS) exposure to investigate if central insulin resistance is induced by an inflammatory stimulus regardless of obesity. Male Wistar rats were treated with single (1 LPS) or repeated injections (6 LPS) of LPS (100 μg/kg, IP) to evaluate the phosphorylation of the insulin receptor substrate-1 (IRS1), Protein kinase B (AKT), and JNK in the hypothalamus. Single LPS increased the expression of pIRS1, pAKT, and pJNK, whereas the repeated LPS treatment failed to recruit pIRS1 and pAKT. The 6 LPS treated rats showed increased total JNK and pJNK. The 6 LPS rats became unresponsive to the hypophagic effect induced by central insulin administration (12 μM/5 μL, ICV). Prolonged exposure to LPS (24 h) impaired the insulin-induced AKT phosphorylation and the translocation of the transcription factor forkhead box protein O1 (FoxO1) from the nucleus to the cytoplasm of the cultured hypothalamic GT1-7 cells. Central administration of the JNK inhibitor (20 μM/5 μL, ICV) restored the ability of insulin to phosphorylate IRS1 and AKT in 6 LPS rats. The present data suggest that an increased JNK activity in the hypothalamus underlies the development of insulin resistance during prolonged exposure to endotoxins. Our study reveals that weight gain is not mandatory for the development of hypothalamic insulin resistance and the blockade of proinflammatory pathways could be useful for restoring the insulin signaling during prolonged low-grade inflammation as seen in obesity.