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Sample records for research platform sarrp

  1. MOSFET assessment of radiation dose delivered to mice using the Small Animal Radiation Research Platform (SARRP).

    Science.gov (United States)

    Ngwa, Wilfred; Korideck, Houari; Chin, Lee M; Makrigiorgos, G Mike; Berbeco, Ross I

    2011-12-01

    The Small Animal Radiation Research Platform (SARRP) is a novel isocentric irradiation system that enables state-of-the-art image-guided radiotherapy research to be performed with animal models. This paper reports the results obtained from investigations assessing the radiation dose delivered by the SARRP to different anatomical target volumes in mice. Surgically implanted metal oxide semiconductor field effect transistors (MOSFET) dosimeters were employed for the dose assessment. The results reveal differences between the calculated and measured dose of -3.5 to 0.5%, -5.2 to -0.7%, -3.9 to 0.5%, -5.9 to 2.5%, -5.5 to 0.5%, and -4.3 to 0% for the left kidney, liver, pancreas, prostate, left lung, and brain, respectively. Overall, the findings show less than 6% difference between the delivered and calculated dose, without tissue heterogeneity corrections. These results provide a useful assessment of the need for tissue heterogeneity corrections in SARRP dose calculations for clinically relevant tumor model sites.

  2. A high resolution small animal radiation research platform (SARRP) with x-ray tomographic guidance capabilities

    Science.gov (United States)

    Wong, John; Armour, Elwood; Kazanzides, Peter; Iordachita, Iulian; Tryggestad, Erik; Deng, Hua; Matinfar, Mohammad; Kennedy, Christopher; Liu, Zejian; Chan, Timothy; Gray, Owen; Verhaegen, Frank; McNutt, Todd; Ford, Eric; DeWeese, Theodore L.

    2008-01-01

    Purpose To demonstrate the CT imaging, conformal irradiation and treatment planning capabilities of a small animal radiation research platform (SARRP). Methods The SARRP employs a dual-focal spot, constant voltage x-ray source mounted on a gantry with a source-to-isocenter distance of 35 cm. Gantry rotation is limited to 120° from vertical. Eighty to 100 kVp x-rays from the smaller 0.4 mm focal spot are used for imaging. Both 0.4 mm and 3.0 mm focal spots operate at 225 kVp for irradiation. Robotic translate/rotate stages are used to position the animal. Cone-beam (CB) CT imaging is achieved by rotating the horizontal animal between the stationary x-ray source and a flat-panel detector. Radiation beams range from 0.5 mm in diameter to (60 × 60) mm2. Dosimetry is measured with radio-chromic films. Monte Carlo dose calculations are employed for treatment planning. The combination of gantry and robotic stage motions facilitate conformal irradiation. Results The SARRP spans 3 ft × 4 ft × 6 ft (WxLxH). Depending on filtration, the isocenter dose outputs at 1 cm depth in water range from 22 to 375 cGy/min from the smallest to the largest radiation fields. The 20% to 80% dose fall-off spans 0.16 mm. CBCT with (0.6 × 0.6 × 0.6) mm3 voxel resolution is acquired with less than 1 cGy. Treatment planning is performed at sub-mm resolution. Conclusions The capability of the SARRP to deliver highly focal beams to multiple animal model systems provides new research opportunities that more realistically bridge laboratory research and clinical translation. PMID:18640502

  3. WE-EF-BRA-01: A Dual-Use Optical Tomography System for Small Animal Radiation Research Platform (SARRP)

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    Wang, K; Bin, Z; Wong, J [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Hospital, Baltimore, MD (United States); He, X; Iordachita, I [Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD (United States)

    2015-06-15

    Purpose: We develop a novel dual-use configuration for a tri-modality, CBCT/bioluminescence tomography(BLT)/fluorescence tomography(FT), imaging system with the SARRP that can function as a standalone system for longitudinal imaging research and on-board the SARRP to guide irradiation. BLT provides radiation guidance for soft tissue target, while FT offers functional information allowing mechanistic investigations. Methods: The optical assembly includes CCD camera, lens, filter wheel, 3-way mirrors, scanning fiber system and light-tight enclosure. The rotating mirror system directs the optical signal from the animal surface to the camera at multiple projection over 180 degree. The fiber-laser system serves as the external light source for the FT application. Multiple filters are used for multispectral imaging to enhance localization accuracy using BLT. SARRP CBCT provides anatomical information and geometric mesh for BLT/FT reconstruction. To facilitate dual use, the 3-way mirror system is cantilevered in front of the camera. The entire optical assembly is driven by a 1D linear stage to dock onto an independent mouse support bed for standalone application. After completion of on-board optical imaging, the system is retracted from the SARRP to allow irradiation of the mouse. Results: A tissue-simulating phantom and a mouse model with a luminescence light source are used to demonstrate the function of the dual-use optical system. Feasibility data have been obtained based on a manual-docking prototype. The center of mass of light source determined in living mouse with on-board BLT is within 1±0.2mm of that with CBCT. The performance of the motorized system is expected to be the same and will be presented. Conclusion: We anticipate the motorized dual use system provide significant efficiency gain over our manual docking and off-line system. By also supporting off-line longitudinal studies independent of the SARRP, the dual-use system is a highly efficient and cost

  4. TH-C-17A-12: Integrated CBCT and Optical Tomography System On-Board a Small Animal Radiation Research Platform (SARRP)

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    Wang, K; Zhang, B; Eslami, S; Iordachita, I; Wong, J [Johns Hopkins University, Baltimore, MD (United States); Patterson, M [Hamilton Regional Cancer Ctr., Hamilton, ON (Canada)

    2014-06-15

    Purpose: We present a newly developed on-board optical tomography system for SARRP. Innovative features include the compact design and fast acquisition optical method to perform 3D soft tissue radiation guidance. Because of the on-board feature and the combination of the CBCT, diffusive optical tomography (DOT), bioluminescence and fluorescence tomography (BLT and FT), this integrated system is expected to provide more accurate soft tissue guidance than an off-line system as well as highly sensitive functional imaging in preclinical research. Methods: Images are acquired in the order of CBCT, DOT and then BLT/FT, where the SARRP CBCT and DOT are used to provide the anatomical and optical properties information to enhance the subsequent BLT/FT optical reconstruction. The SARRP stage is redesigned to include 9 imbedded optical fibers in contact with the animal's skin. These fibers, connected to a white light lamp or laser, serve as the light sources for the DOT or FT, respectively. A CCD camera with f/1.4 lens and multi-spectral filter set is used as the optical detector and is mounted on a portable cart ready to dock into the SARRP. No radiation is delivered during optical image acquisition. A 3-way mirror system capable of 180 degree rotation around the animal reflects the optical signal to the camera at multiple projection angles. A special black-painted dome covers the stage and provides the light shielding. Results: Spontaneous metastatic bioluminescent liver and lung tumor models will be used to validate the 3D BLT reconstruction. To demonstrate the capability of our FT system, GastroSense750 fluorescence agent will be used to imaging the mouse stomach and intestinal region in 3D. Conclusion: We expect that this integrated CBCT and optical tomography on-board a SARRP will present new research opportunities for pre-clinical radiation research. Supported by NCI RO1-CA 158100.

  5. TH-C-17A-12: Integrated CBCT and Optical Tomography System On-Board a Small Animal Radiation Research Platform (SARRP)

    International Nuclear Information System (INIS)

    Wang, K; Zhang, B; Eslami, S; Iordachita, I; Wong, J; Patterson, M

    2014-01-01

    Purpose: We present a newly developed on-board optical tomography system for SARRP. Innovative features include the compact design and fast acquisition optical method to perform 3D soft tissue radiation guidance. Because of the on-board feature and the combination of the CBCT, diffusive optical tomography (DOT), bioluminescence and fluorescence tomography (BLT and FT), this integrated system is expected to provide more accurate soft tissue guidance than an off-line system as well as highly sensitive functional imaging in preclinical research. Methods: Images are acquired in the order of CBCT, DOT and then BLT/FT, where the SARRP CBCT and DOT are used to provide the anatomical and optical properties information to enhance the subsequent BLT/FT optical reconstruction. The SARRP stage is redesigned to include 9 imbedded optical fibers in contact with the animal's skin. These fibers, connected to a white light lamp or laser, serve as the light sources for the DOT or FT, respectively. A CCD camera with f/1.4 lens and multi-spectral filter set is used as the optical detector and is mounted on a portable cart ready to dock into the SARRP. No radiation is delivered during optical image acquisition. A 3-way mirror system capable of 180 degree rotation around the animal reflects the optical signal to the camera at multiple projection angles. A special black-painted dome covers the stage and provides the light shielding. Results: Spontaneous metastatic bioluminescent liver and lung tumor models will be used to validate the 3D BLT reconstruction. To demonstrate the capability of our FT system, GastroSense750 fluorescence agent will be used to imaging the mouse stomach and intestinal region in 3D. Conclusion: We expect that this integrated CBCT and optical tomography on-board a SARRP will present new research opportunities for pre-clinical radiation research. Supported by NCI RO1-CA 158100

  6. MRI-Only Based Radiotherapy Treatment Planning for the Rat Brain on a Small Animal Radiation Research Platform (SARRP.

    Directory of Open Access Journals (Sweden)

    Shandra Gutierrez

    Full Text Available Computed tomography (CT is the standard imaging modality in radiation therapy treatment planning (RTP. However, magnetic resonance (MR imaging provides superior soft tissue contrast, increasing the precision of target volume selection. We present MR-only based RTP for a rat brain on a small animal radiation research platform (SARRP using probabilistic voxel classification with multiple MR sequences. Six rat heads were imaged, each with one CT and five MR sequences. The MR sequences were: T1-weighted, T2-weighted, zero-echo time (ZTE, and two ultra-short echo time sequences with 20 μs (UTE1 and 2 ms (UTE2 echo times. CT data were manually segmented into air, soft tissue, and bone to obtain the RTP reference. Bias field corrected MR images were automatically segmented into the same tissue classes using a fuzzy c-means segmentation algorithm with multiple images as input. Similarities between segmented CT and automatic segmented MR (ASMR images were evaluated using Dice coefficient. Three ASMR images with high similarity index were used for further RTP. Three beam arrangements were investigated. Dose distributions were compared by analysing dose volume histograms. The highest Dice coefficients were obtained for the ZTE-UTE2 combination and for the T1-UTE1-T2 combination when ZTE was unavailable. Both combinations, along with UTE1-UTE2, often used to generate ASMR images, were used for further RTP. Using 1 beam, MR based RTP underestimated the dose to be delivered to the target (range: 1.4%-7.6%. When more complex beam configurations were used, the calculated dose using the ZTE-UTE2 combination was the most accurate, with 0.7% deviation from CT, compared to 0.8% for T1-UTE1-T2 and 1.7% for UTE1-UTE2. The presented MR-only based workflow for RTP on a SARRP enables both accurate organ delineation and dose calculations using multiple MR sequences. This method can be useful in longitudinal studies where CT's cumulative radiation dose might contribute

  7. MRI-Only Based Radiotherapy Treatment Planning for the Rat Brain on a Small Animal Radiation Research Platform (SARRP).

    Science.gov (United States)

    Gutierrez, Shandra; Descamps, Benedicte; Vanhove, Christian

    2015-01-01

    Computed tomography (CT) is the standard imaging modality in radiation therapy treatment planning (RTP). However, magnetic resonance (MR) imaging provides superior soft tissue contrast, increasing the precision of target volume selection. We present MR-only based RTP for a rat brain on a small animal radiation research platform (SARRP) using probabilistic voxel classification with multiple MR sequences. Six rat heads were imaged, each with one CT and five MR sequences. The MR sequences were: T1-weighted, T2-weighted, zero-echo time (ZTE), and two ultra-short echo time sequences with 20 μs (UTE1) and 2 ms (UTE2) echo times. CT data were manually segmented into air, soft tissue, and bone to obtain the RTP reference. Bias field corrected MR images were automatically segmented into the same tissue classes using a fuzzy c-means segmentation algorithm with multiple images as input. Similarities between segmented CT and automatic segmented MR (ASMR) images were evaluated using Dice coefficient. Three ASMR images with high similarity index were used for further RTP. Three beam arrangements were investigated. Dose distributions were compared by analysing dose volume histograms. The highest Dice coefficients were obtained for the ZTE-UTE2 combination and for the T1-UTE1-T2 combination when ZTE was unavailable. Both combinations, along with UTE1-UTE2, often used to generate ASMR images, were used for further RTP. Using 1 beam, MR based RTP underestimated the dose to be delivered to the target (range: 1.4%-7.6%). When more complex beam configurations were used, the calculated dose using the ZTE-UTE2 combination was the most accurate, with 0.7% deviation from CT, compared to 0.8% for T1-UTE1-T2 and 1.7% for UTE1-UTE2. The presented MR-only based workflow for RTP on a SARRP enables both accurate organ delineation and dose calculations using multiple MR sequences. This method can be useful in longitudinal studies where CT's cumulative radiation dose might contribute to the total

  8. Development and implementation of EPID-based quality assurance tests for the small animal radiation research platform (SARRP).

    Science.gov (United States)

    Anvari, Akbar; Poirier, Yannick; Sawant, Amit

    2018-04-28

    Although small animal image-guided radiotherapy (SA-IGRT) systems are used increasingly in preclinical research, tools for performing routine quality assurance (QA) have not been optimized and are not readily available. Robust, efficient, and reliable QA tools are needed to ensure the accuracy and reproducibility of SA-IGRT systems. Several investigators have reported custom-made phantoms and protocols for SA-IGRT systems QA. These are typically time and resource intensive and are therefore not well suited to the preclinical radiotherapy environment, in which physics support is limited and routine QA is performed by technical staff. We investigated the use of the inbuilt electronic portal imaging device (EPID) to develop and validate routine QA tests and procedures. In this work, we focus on the Xstrahl Small Animal Radiation Research Platform (SARRP) EPID. However, the methodology and tests developed here are applicable to any SA-IGRT system that incorporates an EPID. We performed a comprehensive characterization of the dosimetric properties of the camera-based EPID at kilovoltage energies over a 11-month period, including detector warm-up time, radiation dose history effect, stability and short- and long-term reproducibility, gantry angle dependency, output factor, and linearity of the EPID response. We developed a test to measure the constancy of beam quality in terms of half-value layer and tube peak potential using the EPID. We verified the SARRP daily output and beam profile constancy using the imager. We investigated the use of the imager to monitor beam-targeting accuracy at various gantry and couch angles. The EPID response was stable and reproducible, exhibiting maximum variations of ≤0.3% and ≤1.9% for short and long terms, respectively. The detector showed no dependence on response at different gantry angles, with a maximum variation ≤0.5%. We found close agreement in output factor measurement between the portal imager and reference dosimeters

  9. SU-E-T-89: Comprehensive Quality Assurance Phantom for the Small Animal Radiation Research Platform

    International Nuclear Information System (INIS)

    Jermoumi, M; Ngwa, W; Korideck, H; Zygmanski, P; Berbeco, R; Makrigiorgos, G; Cormack, R

    2014-01-01

    Purpose: Use of Small Animal Radiation Research Platform (SARRP) systems for conducting state-of-the-art image guided radiotherapy (IGRT) research on small animals has become more common over the past years. The purpose of this work is to develop and test the suitability and performance of a comprehensive quality assurance (QA) phantom for the SARRP. Methods: A QA phantom was developed for carrying out daily, monthly and annual QA tasks including imaging, dosimetry and treatment planning system (TPS) performance evaluation of the SARRP. The QA phantom consists of nine (60×60×5 mm3) KV-energy tissue equivalent solid water slabs that can be employed for annual dosimetry QA with film. Three of the top slabs are replaceable with ones incorporating Mosfets or OSLDs arranged in a quincunx pattern, or a slab drilled to accommodate an ion chamber insert. These top slabs are designed to facilitate routine daily and monthly QA tasks such as output constancy, isocenter congruency test, treatment planning system (TPS) QA, etc. One slab is designed with inserts for image QA. A prototype of the phantom was applied to test the performance of the imaging, planning and treatment delivery systems. Results: Output constancy test results showed daily variations within 3%. For isocenter congruency test, the phantom could be used to detect 0.3 mm deviations of the CBCT isocenter from the radiation isocenter. Using the Mosfet in phantom as target, the difference between TPS calculations and measurements was within 5%. Image-quality parameters could also be assessed in terms of geometric accuracy, CT number accuracy, linearity, noise and image uniformity, etc. Conclusion: The developed phantom can be employed as a simple tool for comprehensive performance evaluation of the SARRP. The study provides a reference for development of a comprehensive quality assurance program for the SARRP, with proposed tolerances and frequency of required tests

  10. SU-E-T-89: Comprehensive Quality Assurance Phantom for the Small Animal Radiation Research Platform

    Energy Technology Data Exchange (ETDEWEB)

    Jermoumi, M; Ngwa, W [University of Massachusetts Lowell, MA (United States); Dana-Farber Cancer Institute, Brigham and Women' s Hospital, Harvard Medical School, Boston, MA (United States); Korideck, H; Zygmanski, P; Berbeco, R; Makrigiorgos, G; Cormack, R [Dana-Farber Cancer Institute, Brigham and Women' s Hospital, Harvard Medical School, Boston, MA (United States)

    2014-06-01

    Purpose: Use of Small Animal Radiation Research Platform (SARRP) systems for conducting state-of-the-art image guided radiotherapy (IGRT) research on small animals has become more common over the past years. The purpose of this work is to develop and test the suitability and performance of a comprehensive quality assurance (QA) phantom for the SARRP. Methods: A QA phantom was developed for carrying out daily, monthly and annual QA tasks including imaging, dosimetry and treatment planning system (TPS) performance evaluation of the SARRP. The QA phantom consists of nine (60×60×5 mm3) KV-energy tissue equivalent solid water slabs that can be employed for annual dosimetry QA with film. Three of the top slabs are replaceable with ones incorporating Mosfets or OSLDs arranged in a quincunx pattern, or a slab drilled to accommodate an ion chamber insert. These top slabs are designed to facilitate routine daily and monthly QA tasks such as output constancy, isocenter congruency test, treatment planning system (TPS) QA, etc. One slab is designed with inserts for image QA. A prototype of the phantom was applied to test the performance of the imaging, planning and treatment delivery systems. Results: Output constancy test results showed daily variations within 3%. For isocenter congruency test, the phantom could be used to detect 0.3 mm deviations of the CBCT isocenter from the radiation isocenter. Using the Mosfet in phantom as target, the difference between TPS calculations and measurements was within 5%. Image-quality parameters could also be assessed in terms of geometric accuracy, CT number accuracy, linearity, noise and image uniformity, etc. Conclusion: The developed phantom can be employed as a simple tool for comprehensive performance evaluation of the SARRP. The study provides a reference for development of a comprehensive quality assurance program for the SARRP, with proposed tolerances and frequency of required tests.

  11. A comprehensive system for dosimetric commissioning and Monte Carlo validation for the small animal radiation research platform.

    Science.gov (United States)

    Tryggestad, E; Armour, M; Iordachita, I; Verhaegen, F; Wong, J W

    2009-09-07

    Our group has constructed the small animal radiation research platform (SARRP) for delivering focal, kilo-voltage radiation to targets in small animals under robotic control using cone-beam CT guidance. The present work was undertaken to support the SARRP's treatment planning capabilities. We have devised a comprehensive system for characterizing the radiation dosimetry in water for the SARRP and have developed a Monte Carlo dose engine with the intent of reproducing these measured results. We find that the SARRP provides sufficient therapeutic dose rates ranging from 102 to 228 cGy min(-1) at 1 cm depth for the available set of high-precision beams ranging from 0.5 to 5 mm in size. In terms of depth-dose, the mean of the absolute percentage differences between the Monte Carlo calculations and measurement is 3.4% over the full range of sampled depths spanning 0.5-7.2 cm for the 3 and 5 mm beams. The measured and computed profiles for these beams agree well overall; of note, good agreement is observed in the profile tails. Especially for the smallest 0.5 and 1 mm beams, including a more realistic description of the effective x-ray source into the Monte Carlo model may be important.

  12. A comprehensive system for dosimetric commissioning and Monte Carlo validation for the small animal radiation research platform

    Energy Technology Data Exchange (ETDEWEB)

    Tryggestad, E; Armour, M; Wong, J W [Deptartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, MD (United States); Iordachita, I [Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD (United States); Verhaegen, F [Department of Radiation Oncology (MAASTRO Physics), GROW School, Maastricht University Medical Center, Maastricht (Netherlands)

    2009-09-07

    Our group has constructed the small animal radiation research platform (SARRP) for delivering focal, kilo-voltage radiation to targets in small animals under robotic control using cone-beam CT guidance. The present work was undertaken to support the SARRP's treatment planning capabilities. We have devised a comprehensive system for characterizing the radiation dosimetry in water for the SARRP and have developed a Monte Carlo dose engine with the intent of reproducing these measured results. We find that the SARRP provides sufficient therapeutic dose rates ranging from 102 to 228 cGy min{sup -1} at 1 cm depth for the available set of high-precision beams ranging from 0.5 to 5 mm in size. In terms of depth-dose, the mean of the absolute percentage differences between the Monte Carlo calculations and measurement is 3.4% over the full range of sampled depths spanning 0.5-7.2 cm for the 3 and 5 mm beams. The measured and computed profiles for these beams agree well overall; of note, good agreement is observed in the profile tails. Especially for the smallest 0.5 and 1 mm beams, including a more realistic description of the effective x-ray source into the Monte Carlo model may be important.

  13. Image-guided small animal radiation research platform: calibration of treatment beam alignment

    International Nuclear Information System (INIS)

    Matinfar, Mohammad; Iordachita, Iulian; Kazanzides, Peter; Ford, Eric; Wong, John

    2009-01-01

    Small animal research allows detailed study of biological processes, disease progression and response to therapy with the potential to provide a natural bridge to the clinical environment. The small animal radiation research platform (SARRP) is a portable system for precision irradiation with beam sizes down to approximately 0.5 mm and optimally planned radiation with on-board cone-beam CT (CBCT) guidance. This paper focuses on the geometric calibration of the system for high-precision irradiation. A novel technique for the calibration of the treatment beam is presented, which employs an x-ray camera whose precise positioning need not be known. Using the camera system we acquired a digitally reconstructed 3D 'star shot' for gantry calibration and then developed a technique to align each beam to a common isocenter with the robotic animal positioning stages. The calibration incorporates localization by cone-beam CT guidance. Uncorrected offsets of the beams with respect to the calibration origin ranged from 0.4 mm to 5.2 mm. With corrections, these alignment errors can be reduced to the sub-millimeter range. The calibration technique was used to deliver a stereotactic-like arc treatment to a phantom constructed with EBT Gafchromic films. All beams were shown to intersect at a common isocenter with a measured beam (FWHM) of approximately 1.07 mm using the 0.5 mm collimated beam. The desired positioning accuracy of the SARRP is 0.25 mm and the results indicate an accuracy of 0.2 mm. To fully realize the radiation localization capabilities of the SARRP, precise geometric calibration is required, as with any such system. The x-ray camera-based technique presented here provides a straightforward and semi-automatic method for system calibration.

  14. The small-animal radiation research platform (SARRP): dosimetry of a focused lens system

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    Deng Hua [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Kennedy, Christopher W [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Armour, Elwood [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Tryggestad, Erik [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Ford, Eric [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); McNutt, Todd [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Jiang Licai [OSMIC Inc., 1900 Taylor Rd., Auburn Hills, MI (United States); Wong, John [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States)

    2007-05-21

    A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min{sup -1} at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of {+-}5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD.

  15. The small-animal radiation research platform (SARRP): dosimetry of a focused lens system.

    Science.gov (United States)

    Deng, Hua; Kennedy, Christopher W; Armour, Elwood; Tryggestad, Erik; Ford, Eric; McNutt, Todd; Jiang, Licai; Wong, John

    2007-05-21

    A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min(-1) at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of +/-5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD.

  16. The small-animal radiation research platform (SARRP): dosimetry of a focused lens system

    International Nuclear Information System (INIS)

    Deng Hua; Kennedy, Christopher W; Armour, Elwood; Tryggestad, Erik; Ford, Eric; McNutt, Todd; Jiang Licai; Wong, John

    2007-01-01

    A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min -1 at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of ±5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD

  17. Bioluminescence Tomography–Guided Radiation Therapy for Preclinical Research

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    Zhang, Bin [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland (United States); Wang, Ken Kang-Hsin, E-mail: kwang27@jhmi.edu [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland (United States); Yu, Jingjing [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland (United States); School of Physics and Information Technology, Shaanxi Normal University, Shaanxi (China); Eslami, Sohrab; Iordachita, Iulian [Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, Maryland (United States); Reyes, Juvenal; Malek, Reem [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland (United States); Tran, Phuoc T. [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland (United States); Department of Oncology and Urology, Brady Urological Institute, Johns Hopkins University, Baltimore, Maryland (United States); Patterson, Michael S. [Department of Medical Physics and Applied Radiation Sciences, McMaster University, Hamilton, Ontario (Canada); Wong, John W. [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland (United States)

    2016-04-01

    Purpose: In preclinical radiation research, it is challenging to localize soft tissue targets based on cone beam computed tomography (CBCT) guidance. As a more effective method to localize soft tissue targets, we developed an online bioluminescence tomography (BLT) system for small-animal radiation research platform (SARRP). We demonstrated BLT-guided radiation therapy and validated targeting accuracy based on a newly developed reconstruction algorithm. Methods and Materials: The BLT system was designed to dock with the SARRP for image acquisition and to be detached before radiation delivery. A 3-mirror system was devised to reflect the bioluminescence emitted from the subject to a stationary charge-coupled device (CCD) camera. Multispectral BLT and the incomplete variables truncated conjugate gradient method with a permissible region shrinking strategy were used as the optimization scheme to reconstruct bioluminescent source distributions. To validate BLT targeting accuracy, a small cylindrical light source with high CBCT contrast was placed in a phantom and also in the abdomen of a mouse carcass. The center of mass (CoM) of the source was recovered from BLT and used to guide radiation delivery. The accuracy of the BLT-guided targeting was validated with films and compared with the CBCT-guided delivery. In vivo experiments were conducted to demonstrate BLT localization capability for various source geometries. Results: Online BLT was able to recover the CoM of the embedded light source with an average accuracy of 1 mm compared to that with CBCT localization. Differences between BLT- and CBCT-guided irradiation shown on the films were consistent with the source localization revealed in the BLT and CBCT images. In vivo results demonstrated that our BLT system could potentially be applied for multiple targets and tumors. Conclusions: The online BLT/CBCT/SARRP system provides an effective solution for soft tissue targeting, particularly for small, nonpalpable, or

  18. Bioluminescence Tomography–Guided Radiation Therapy for Preclinical Research

    International Nuclear Information System (INIS)

    Zhang, Bin; Wang, Ken Kang-Hsin; Yu, Jingjing; Eslami, Sohrab; Iordachita, Iulian; Reyes, Juvenal; Malek, Reem; Tran, Phuoc T.; Patterson, Michael S.; Wong, John W.

    2016-01-01

    Purpose: In preclinical radiation research, it is challenging to localize soft tissue targets based on cone beam computed tomography (CBCT) guidance. As a more effective method to localize soft tissue targets, we developed an online bioluminescence tomography (BLT) system for small-animal radiation research platform (SARRP). We demonstrated BLT-guided radiation therapy and validated targeting accuracy based on a newly developed reconstruction algorithm. Methods and Materials: The BLT system was designed to dock with the SARRP for image acquisition and to be detached before radiation delivery. A 3-mirror system was devised to reflect the bioluminescence emitted from the subject to a stationary charge-coupled device (CCD) camera. Multispectral BLT and the incomplete variables truncated conjugate gradient method with a permissible region shrinking strategy were used as the optimization scheme to reconstruct bioluminescent source distributions. To validate BLT targeting accuracy, a small cylindrical light source with high CBCT contrast was placed in a phantom and also in the abdomen of a mouse carcass. The center of mass (CoM) of the source was recovered from BLT and used to guide radiation delivery. The accuracy of the BLT-guided targeting was validated with films and compared with the CBCT-guided delivery. In vivo experiments were conducted to demonstrate BLT localization capability for various source geometries. Results: Online BLT was able to recover the CoM of the embedded light source with an average accuracy of 1 mm compared to that with CBCT localization. Differences between BLT- and CBCT-guided irradiation shown on the films were consistent with the source localization revealed in the BLT and CBCT images. In vivo results demonstrated that our BLT system could potentially be applied for multiple targets and tumors. Conclusions: The online BLT/CBCT/SARRP system provides an effective solution for soft tissue targeting, particularly for small, nonpalpable, or

  19. The COMET Sleep Research Platform.

    Science.gov (United States)

    Nichols, Deborah A; DeSalvo, Steven; Miller, Richard A; Jónsson, Darrell; Griffin, Kara S; Hyde, Pamela R; Walsh, James K; Kushida, Clete A

    2014-01-01

    The Comparative Outcomes Management with Electronic Data Technology (COMET) platform is extensible and designed for facilitating multicenter electronic clinical research. Our research goals were the following: (1) to conduct a comparative effectiveness trial (CET) for two obstructive sleep apnea treatments-positive airway pressure versus oral appliance therapy; and (2) to establish a new electronic network infrastructure that would support this study and other clinical research studies. The COMET platform was created to satisfy the needs of CET with a focus on creating a platform that provides comprehensive toolsets, multisite collaboration, and end-to-end data management. The platform also provides medical researchers the ability to visualize and interpret data using business intelligence (BI) tools. COMET is a research platform that is scalable and extensible, and which, in a future version, can accommodate big data sets and enable efficient and effective research across multiple studies and medical specialties. The COMET platform components were designed for an eventual move to a cloud computing infrastructure that enhances sustainability, overall cost effectiveness, and return on investment.

  20. Stereotactic Body Radiation Therapy Delivery in a Genetically Engineered Mouse Model of Lung Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Du, Shisuo; Lockamy, Virginia [Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania (United States); Zhou, Lin [Department of Thoracic Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan (China); Xue, Christine; LeBlanc, Justin [Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania (United States); Glenn, Shonna [Xstrahl, Inc, Suwanee, Georgia (United States); Shukla, Gaurav; Yu, Yan; Dicker, Adam P.; Leeper, Dennis B. [Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania (United States); Lu, You [Department of Thoracic Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan (China); Lu, Bo, E-mail: bo.lu@jefferson.edu [Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania (United States)

    2016-11-01

    Purpose: To implement clinical stereotactic body radiation therapy (SBRT) using a small animal radiation research platform (SARRP) in a genetically engineered mouse model of lung cancer. Methods and Materials: A murine model of multinodular Kras-driven spontaneous lung tumors was used for this study. High-resolution cone beam computed tomography (CBCT) imaging was used to identify and target peripheral tumor nodules, whereas off-target lung nodules in the contralateral lung were used as a nonirradiated control. CBCT imaging helps localize tumors, facilitate high-precision irradiation, and monitor tumor growth. SBRT planning, prescription dose, and dose limits to normal tissue followed the guidelines set by RTOG protocols. Pathologic changes in the irradiated tumors were investigated using immunohistochemistry. Results: The image guided radiation delivery using the SARRP system effectively localized and treated lung cancer with precision in a genetically engineered mouse model of lung cancer. Immunohistochemical data confirmed the precise delivery of SBRT to the targeted lung nodules. The 60 Gy delivered in 3 weekly fractions markedly reduced the proliferation index, Ki-67, and increased apoptosis per staining for cleaved caspase-3 in irradiated lung nodules. Conclusions: It is feasible to use the SARRP platform to perform dosimetric planning and delivery of SBRT in mice with lung cancer. This allows for preclinical studies that provide a rationale for clinical trials involving SBRT, especially when combined with immunotherapeutics.

  1. Small animal radiotherapy research platforms

    Energy Technology Data Exchange (ETDEWEB)

    Verhaegen, Frank; Granton, Patrick [Department of Radiation Oncology (MAASTRO), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht 6201 BN (Netherlands); Tryggestad, Erik, E-mail: frank.verhaegen@maastro.nl [Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21231 (United States)

    2011-06-21

    Advances in conformal radiation therapy and advancements in pre-clinical radiotherapy research have recently stimulated the development of precise micro-irradiators for small animals such as mice and rats. These devices are often kilovolt x-ray radiation sources combined with high-resolution CT imaging equipment for image guidance, as the latter allows precise and accurate beam positioning. This is similar to modern human radiotherapy practice. These devices are considered a major step forward compared to the current standard of animal experimentation in cancer radiobiology research. The availability of this novel equipment enables a wide variety of pre-clinical experiments on the synergy of radiation with other therapies, complex radiation schemes, sub-target boost studies, hypofractionated radiotherapy, contrast-enhanced radiotherapy and studies of relative biological effectiveness, to name just a few examples. In this review we discuss the required irradiation and imaging capabilities of small animal radiation research platforms. We describe the need for improved small animal radiotherapy research and highlight pioneering efforts, some of which led recently to commercially available prototypes. From this, it will be clear that much further development is still needed, on both the irradiation side and imaging side. We discuss at length the need for improved treatment planning tools for small animal platforms, and the current lack of a standard therein. Finally, we mention some recent experimental work using the early animal radiation research platforms, and the potential they offer for advancing radiobiology research. (topical review)

  2. Small animal radiotherapy research platforms

    Science.gov (United States)

    Verhaegen, Frank; Granton, Patrick; Tryggestad, Erik

    2011-06-01

    Advances in conformal radiation therapy and advancements in pre-clinical radiotherapy research have recently stimulated the development of precise micro-irradiators for small animals such as mice and rats. These devices are often kilovolt x-ray radiation sources combined with high-resolution CT imaging equipment for image guidance, as the latter allows precise and accurate beam positioning. This is similar to modern human radiotherapy practice. These devices are considered a major step forward compared to the current standard of animal experimentation in cancer radiobiology research. The availability of this novel equipment enables a wide variety of pre-clinical experiments on the synergy of radiation with other therapies, complex radiation schemes, sub-target boost studies, hypofractionated radiotherapy, contrast-enhanced radiotherapy and studies of relative biological effectiveness, to name just a few examples. In this review we discuss the required irradiation and imaging capabilities of small animal radiation research platforms. We describe the need for improved small animal radiotherapy research and highlight pioneering efforts, some of which led recently to commercially available prototypes. From this, it will be clear that much further development is still needed, on both the irradiation side and imaging side. We discuss at length the need for improved treatment planning tools for small animal platforms, and the current lack of a standard therein. Finally, we mention some recent experimental work using the early animal radiation research platforms, and the potential they offer for advancing radiobiology research.

  3. Small animal radiotherapy research platforms

    International Nuclear Information System (INIS)

    Verhaegen, Frank; Granton, Patrick; Tryggestad, Erik

    2011-01-01

    Advances in conformal radiation therapy and advancements in pre-clinical radiotherapy research have recently stimulated the development of precise micro-irradiators for small animals such as mice and rats. These devices are often kilovolt x-ray radiation sources combined with high-resolution CT imaging equipment for image guidance, as the latter allows precise and accurate beam positioning. This is similar to modern human radiotherapy practice. These devices are considered a major step forward compared to the current standard of animal experimentation in cancer radiobiology research. The availability of this novel equipment enables a wide variety of pre-clinical experiments on the synergy of radiation with other therapies, complex radiation schemes, sub-target boost studies, hypofractionated radiotherapy, contrast-enhanced radiotherapy and studies of relative biological effectiveness, to name just a few examples. In this review we discuss the required irradiation and imaging capabilities of small animal radiation research platforms. We describe the need for improved small animal radiotherapy research and highlight pioneering efforts, some of which led recently to commercially available prototypes. From this, it will be clear that much further development is still needed, on both the irradiation side and imaging side. We discuss at length the need for improved treatment planning tools for small animal platforms, and the current lack of a standard therein. Finally, we mention some recent experimental work using the early animal radiation research platforms, and the potential they offer for advancing radiobiology research. (topical review)

  4. Development of a novel preclinical pancreatic cancer research model: bioluminescence image-guided focal irradiation and tumor monitoring of orthotopic xenografts.

    Science.gov (United States)

    Tuli, Richard; Surmak, Andrew; Reyes, Juvenal; Hacker-Prietz, Amy; Armour, Michael; Leubner, Ashley; Blackford, Amanda; Tryggestad, Erik; Jaffee, Elizabeth M; Wong, John; Deweese, Theodore L; Herman, Joseph M

    2012-04-01

    We report on a novel preclinical pancreatic cancer research model that uses bioluminescence imaging (BLI)-guided irradiation of orthotopic xenograft tumors, sparing of surrounding normal tissues, and quantitative, noninvasive longitudinal assessment of treatment response. Luciferase-expressing MiaPaCa-2 pancreatic carcinoma cells were orthotopically injected in nude mice. BLI was compared to pathologic tumor volume, and photon emission was assessed over time. BLI was correlated to positron emission tomography (PET)/computed tomography (CT) to estimate tumor dimensions. BLI and cone-beam CT (CBCT) were used to compare tumor centroid location and estimate setup error. BLI and CBCT fusion was performed to guide irradiation of tumors using the small animal radiation research platform (SARRP). DNA damage was assessed by γ-H2Ax staining. BLI was used to longitudinally monitor treatment response. Bioluminescence predicted tumor volume (R = 0.8984) and increased linearly as a function of time up to a 10-fold increase in tumor burden. BLI correlated with PET/CT and necropsy specimen in size (P < .05). Two-dimensional BLI centroid accuracy was 3.5 mm relative to CBCT. BLI-guided irradiated pancreatic tumors stained positively for γ-H2Ax, whereas surrounding normal tissues were spared. Longitudinal assessment of irradiated tumors with BLI revealed significant tumor growth delay of 20 days relative to controls. We have successfully applied the SARRP to a bioluminescent, orthotopic preclinical pancreas cancer model to noninvasively: 1) allow the identification of tumor burden before therapy, 2) facilitate image-guided focal radiation therapy, and 3) allow normalization of tumor burden and longitudinal assessment of treatment response.

  5. Researching intimacy through social media: A cross-platform approach

    OpenAIRE

    Miguel, C

    2016-01-01

    This paper aims to contribute to the understanding of how to study the way people build intimacy and manage privacy through social media interaction. It explores the research design and methodology of a research project based on a multi-sited case study composed of three different social media platforms: Badoo, CouchSurfing, and Facebook. This cross-platform approach is useful to observe how intimacy is often negotiated across different platforms. The research project focuses on the cities of...

  6. Researching intimacy through social media: A cross-platform approach

    Directory of Open Access Journals (Sweden)

    Cristina Miguel

    2016-06-01

    Full Text Available This paper aims to contribute to the understanding of how to study the way people build intimacy and manage privacy through social media interaction. It explores the research design and methodology of a research project based on a multi-sited case study composed of three different social media platforms: Badoo, CouchSurfing, and Facebook. This cross-platform approach is useful to observe how intimacy is often negotiated across different platforms. The research project focuses on the cities of Leeds (UK and Barcelona (Spain. In particular, this article discusses the methods used to recruit participants and collect data for that study - namely, participant observation, semi-structured interviews, and user profiles analysis. This cross-platform approach and multi-method research design is helpful to investigate the nature of intimacy practices facilitated by social media at several levels: online/offline, across different platforms, among different types of relationships, within both new and existing relationships, and in different locations

  7. Reconcile: A Coreference Resolution Research Platform

    Energy Technology Data Exchange (ETDEWEB)

    Stoyanov, V; Cardie, C; Gilbert, N; Riloff, E; Buttler, D; Hysom, D

    2009-10-29

    Despite the availability of standard data sets and metrics, approaches to the problem of noun phrase coreference resolution are hard to compare empirically due to the different evaluation setting stemming, in part, from the lack of comprehensive coreference resolution research platforms. In this tech report we present Reconcile, a coreference resolution research platform that aims to facilitate the implementation of new approaches to coreference resolution as well as the comparison of existing approaches. We discuss Reconcile's architecture and give results of running Reconcile on six data sets using four evaluation metrics, showing that Reconcile's performance is comparable to state-of-the-art systems in coreference resolution.

  8. SU-C-303-04: Evaluation of On- and Off-Line Bioluminescence Tomography System for Focal Irradiation Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, B; Wang, K; Reyes, J; Tran, P; Wong, J [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, MD (United States); Iordachita, I [Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD (United States)

    2015-06-15

    Purpose: We have developed offline and on-board bioluminescence tomography(BLT) systems for the small animal radiation research platform(SARRP) for radiation guidance of soft tissue targets. We investigated the effectiveness of offline BLT guidance. Methods: CBCT is equipped on both the offline BLT system and SARRP that are 10 ft. apart. To evaluate the setup error during animal transport between the two systems, we implanted a luminescence source in the abdomen of anesthetized mice. Five mice were studied. After CBCT was acquired on both systems, source centers and correlation coefficients were calculated. CBCT was also used to generate object mesh for BLT reconstruction. To assess target localization, we compared the localization of the luminescence source based on (1)on-board SARRP BLT and CBCT, (2)offline BLT and CBCT, and (3)offline BLT and SARRP CBCT. The 3rd comparison examines if an offline BLT system can be used to guide radiation when there is minimal target contrast in CBCT. Results: Our CBCT results show the offset of the light source center can be maintained within 0.2 mm during animal transport. The center of mass(CoM) of the light source reconstructed by the offline BLT has an offset of 1.0 ± 0.4 mm from the ‘true’ CoM as derived from the SARRP CBCT. The results compare well with the offset of 1.0 ± 0.2 mm using on-line BLT. Conclusion: With CBCT information provided by the SARRP and effective animal immobilization during transport, these findings support the use of offline BLT in close vicinity for accurate soft tissue target localization for irradiation. However, the disadvantage of the off-line system is reduced efficiency as care is required to maintain stable animal transport. We envisage a dual use system where the on-board arrangement allows convenient access to CBCT and avoids disturbance of animal setup. The off-line capability would support standalone longitudinal imaging studies. The work is supported by NIH R01CA158100 and Xstrahl

  9. Development of a Novel Preclinical Pancreatic Cancer Research Model: Bioluminescence Image-Guided Focal Irradiation and Tumor Monitoring of Orthotopic Xenografts1

    Science.gov (United States)

    Tuli, Richard; Surmak, Andrew; Reyes, Juvenal; Hacker-Prietz, Amy; Armour, Michael; Leubner, Ashley; Blackford, Amanda; Tryggestad, Erik; Jaffee, Elizabeth M; Wong, John; DeWeese, Theodore L; Herman, Joseph M

    2012-01-01

    PURPOSE: We report on a novel preclinical pancreatic cancer research model that uses bioluminescence imaging (BLI)-guided irradiation of orthotopic xenograft tumors, sparing of surrounding normal tissues, and quantitative, noninvasive longitudinal assessment of treatment response. MATERIALS AND METHODS: Luciferase-expressing MiaPaCa-2 pancreatic carcinoma cells were orthotopically injected in nude mice. BLI was compared to pathologic tumor volume, and photon emission was assessed over time. BLI was correlated to positron emission tomography (PET)/computed tomography (CT) to estimate tumor dimensions. BLI and cone-beam CT (CBCT) were used to compare tumor centroid location and estimate setup error. BLI and CBCT fusion was performed to guide irradiation of tumors using the small animal radiation research platform (SARRP). DNA damage was assessed by γ-H2Ax staining. BLI was used to longitudinally monitor treatment response. RESULTS: Bioluminescence predicted tumor volume (R = 0.8984) and increased linearly as a function of time up to a 10-fold increase in tumor burden. BLI correlated with PET/CT and necropsy specimen in size (P < .05). Two-dimensional BLI centroid accuracy was 3.5 mm relative to CBCT. BLI-guided irradiated pancreatic tumors stained positively for γ-H2Ax, whereas surrounding normal tissues were spared. Longitudinal assessment of irradiated tumors with BLI revealed significant tumor growth delay of 20 days relative to controls. CONCLUSIONS: We have successfully applied the SARRP to a bioluminescent, orthotopic preclinical pancreas cancer model to noninvasively: 1) allow the identification of tumor burden before therapy, 2) facilitate image-guided focal radiation therapy, and 3) allow normalization of tumor burden and longitudinal assessment of treatment response. PMID:22496923

  10. Research of Snow-Melt Process on a Heated Platform

    Directory of Open Access Journals (Sweden)

    Vasilyev Gregory P.

    2016-01-01

    Full Text Available The article has shown the results of experimental researches of the snow-melt on a heated platform-near building heat-pump snow-melt platform. The near-building (yard heat pump platforms for snow melt with the area up to 10-15 m2 are a basis of the new ideology of organization of the street cleaning of Moscow from snow in the winter period which supposes the creation in the megalopolis of the «distributed snow-melt system» (DSMS using non-traditional energy sources. The results of natural experimental researches are presented for the estimation of efficiency of application in the climatic conditions of Moscow of heat pumps in the snow-melt systems. The researches were conducted on a model sample of the near-building heat-pump platform which uses the low-potential thermal energy of atmospheric air. The conducted researches have confirmed experimentally in the natural conditions the possibility and efficiency of using of atmospheric air as a source of low-potential thermal energy for evaporation of the snow-melt heat pump systems in the climatic conditions of Moscow. The results of laboratory researches of snow-melt process on a heated horizontal platform are presented. The researches have revealed a considerable dependence of efficiency of the snow-melt process on its piling mode (form-building and the organization of the process of its piling mode (form-building and the organization of the process of its (snow mass heat exchange with the surface of the heated platform. In the process of researches the effect of formation of an «ice dome» under the melting snow mass called by the fact that in case of the thickness of snow loaded on the platform more than 10 cm the water formed from the melting snow while the contact with the heating surface don’t spread on it, but soaks into the snow, wets it due to capillary effect and freezes. The formation of «ice dome» leads to a sharp increase of snow-melt period and decreases the operating

  11. Creating a platform for collaborative genomic research

    Directory of Open Access Journals (Sweden)

    Mark Smithson

    2017-04-01

    The developed genomics informatics platform provides a step-change in this type of genetic research, accelerating reproducible collaborative research across multiple disparate organisations and data sources, of varying type and complexity.

  12. ServiceNow as a platform – practical research

    OpenAIRE

    Nechyporenko, Tamara

    2015-01-01

    In this thesis I am going to cover the main aspects of ServiceNow platform, what is it, and related areas to ServiceNow technologies such as cloud service technologies and ITIL framework, how it is used in ServiceNow. All the definitions and descriptions will be in details and a reader can get the important terms and definitions. The main scope of the thesis is practical research and creation of portal based on that research. The portal will be implemented using ServiceNow platform, Servic...

  13. BioXmark for high-precision radiotherapy in an orthotopic pancreatic tumor mouse model. Experiences with a liquid fiducial marker

    Energy Technology Data Exchange (ETDEWEB)

    Dobiasch, S. [Technical University of Munich (TUM), Klinikum rechts der Isar, Department of Radiation Oncology, Munich (Germany); Deutsches Konsortium fuer Translationale Krebsforschung (DKTK), Munich (Germany); Kampfer, S. [Technical University of Munich (TUM), Klinikum rechts der Isar, Department of Radiation Oncology, Munich (Germany); Technical University of Munich (TUM), Physics Department, Garching (Germany); Burkhardt, R.; Wilkens, J.J. [Technical University of Munich (TUM), Klinikum rechts der Isar, Department of Radiation Oncology, Munich (Germany); Helmholtz Zentrum Muenchen, Institute of Innovative Radiotherapy (iRT), Department of Radiation Sciences (DRS), Neuherberg (Germany); Technical University of Munich (TUM), Physics Department, Garching (Germany); Schilling, D.; Schmid, T.E. [Technical University of Munich (TUM), Klinikum rechts der Isar, Department of Radiation Oncology, Munich (Germany); Helmholtz Zentrum Muenchen, Institute of Innovative Radiotherapy (iRT), Department of Radiation Sciences (DRS), Neuherberg (Germany); Combs, S.E. [Technical University of Munich (TUM), Klinikum rechts der Isar, Department of Radiation Oncology, Munich (Germany); Helmholtz Zentrum Muenchen, Institute of Innovative Radiotherapy (iRT), Department of Radiation Sciences (DRS), Neuherberg (Germany); Deutsches Konsortium fuer Translationale Krebsforschung (DKTK), Munich (Germany)

    2017-12-15

    High-precision radiotherapy (RT) requires precise positioning, particularly with high single doses. Fiducial markers in combination with onboard imaging are excellent tools to support this. The purpose of this study is to establish a pancreatic cancer mouse model for high-precision image-guided RT (IGRT) using the liquid fiducial marker BioXmark (Nanovi, Kongens Lyngby, Denmark). In an animal-based cancer model, different volumes of BioXmark (10-50 μl), application forms, and imaging modalities - cone-beam computer tomography (CBCT) incorporated in either the Small Animal Radiation Research Platform (SARRP) or the small-animal micro-CT Scanner (SkyScan; Bruker, Brussels, Belgium) - as well as subsequent RT with the SARRP system were analyzed to derive recommendations for BioXmark. Even small volumes (10 μl) of BioXmark could be detected by CBCT (SARRP and Skyscan). Larger volumes (50 μl) led to hardening artefacts. The position of BioXmark was monitored at least weekly by CBCT and was stable over 4 months. BioXmark was shown to be well tolerated; no changes in physical condition or toxic side effects were observed in comparison to control mice. BioXmark enabled an exact fusion with the original treatment plan with less hardening artefacts, and minimized the application of contrast agent for fractionated RT. An orthotopic pancreatic tumor mouse model was established for high-precision IGRT using a fiducial marker. BioXmark was successfully tested and provides the perfect basis for improved imaging in high-precision RT. BioXmark enables a unique application method and optimal targeted precision in fractionated RT. Therefore, preclinical trials evaluating novel fractionation regimens and/or combination treatment with high-end RT can be performed. (orig.) [German] Die Hochpraezisionsstrahlentherapie (RT) erfordert insbesondere bei hohen Einzeldosen eine exakte Lagerung. Marker in Kombination mit integrierten Bildgebungsverfahren koennen dies optimal gewaehrleisten

  14. Nuclear platform research and development - 2008-09 highlights

    International Nuclear Information System (INIS)

    Sadhankar, R.R.

    2009-08-01

    The Nuclear Platform R and D Program has lead responsibility for the maintenance and further development of the CANDU intellectual property covering the safety, licensing and design basis for nuclear facilities. The Nuclear Platform R and D Program is part of the Research and Technology Operation (RTO) unit of AECL and is managed through the Research and Development division, which has responsibility for maintaining and enhancing the knowledge and technology base. The RTO is also responsible for managing AECL's nuclear facilities and infrastructure (including laboratories and R and D facilities), the nuclear waste management program and other legacy liabilities (e.g., decommissioning) to demonstrate and grow shareholder value. The Nuclear Platform also provides the technology base from which new products and services can be developed to meet customer needs (including ACR and commercial products and services). (author)

  15. Development of a Modular Research Platform to Create Medical Observational Studies for Mobile Devices.

    Science.gov (United States)

    Zens, Martin; Grotejohann, Birgit; Tassoni, Adrian; Duttenhoefer, Fabian; Südkamp, Norbert P; Niemeyer, Philipp

    2017-05-23

    Observational studies have proven to be a valuable resource in medical research, especially when performed on a large scale. Recently, mobile device-based observational studies have been discovered by an increasing number of researchers as a promising new source of information. However, the development and deployment of app-based studies is not trivial and requires profound programming skills. The aim of this project was to develop a modular online research platform that allows researchers to create medical studies for mobile devices without extensive programming skills. The platform approach for a modular research platform consists of three major components. A Web-based platform forms the researchers' main workplace. This platform communicates via a shared database with a platform independent mobile app. Furthermore, a separate Web-based login platform for physicians and other health care professionals is outlined and completes the concept. A prototype of the research platform has been developed and is currently in beta testing. Simple questionnaire studies can be created within minutes and published for testing purposes. Screenshots of an example study are provided, and the general working principle is displayed. In this project, we have created a basis for a novel research platform. The necessity and implications of a modular approach were displayed and an outline for future development given. International researchers are invited and encouraged to participate in this ongoing project. ©Martin Zens, Birgit Grotejohann, Adrian Tassoni, Fabian Duttenhoefer, Norbert P Südkamp, Philipp Niemeyer. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 23.05.2017.

  16. eTRIKS platform: Conception and operation of a highly scalable cloud-based platform for translational research and applications development.

    Science.gov (United States)

    Bussery, Justin; Denis, Leslie-Alexandre; Guillon, Benjamin; Liu, Pengfeï; Marchetti, Gino; Rahal, Ghita

    2018-04-01

    We describe the genesis, design and evolution of a computing platform designed and built to improve the success rate of biomedical translational research. The eTRIKS project platform was developed with the aim of building a platform that can securely host heterogeneous types of data and provide an optimal environment to run tranSMART analytical applications. Many types of data can now be hosted, including multi-OMICS data, preclinical laboratory data and clinical information, including longitudinal data sets. During the last two years, the platform has matured into a robust translational research knowledge management system that is able to host other data mining applications and support the development of new analytical tools. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. Multi-donor Research Platform on Social Protection, Financial ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Multi-donor Research Platform on Social Protection, Financial Inclusion and ... There have been some experiments linking a financial inclusion component to CCT programs, ... Universidad de Chile. Institution Country. Chile. Institution Website.

  18. Multi-donor Research Platform on Social Protection, Financial ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Multi-donor Research Platform on Social Protection, Financial Inclusion and ICTs ... been some experiments linking a financial inclusion component to CCT programs, ... Institution. Universidad de Chile. Pays d' institution. Chile. Site internet.

  19. New Tools for New Research in Psychiatry: A Scalable and Customizable Platform to Empower Data Driven Smartphone Research.

    Science.gov (United States)

    Torous, John; Kiang, Mathew V; Lorme, Jeanette; Onnela, Jukka-Pekka

    2016-05-05

    A longstanding barrier to progress in psychiatry, both in clinical settings and research trials, has been the persistent difficulty of accurately and reliably quantifying disease phenotypes. Mobile phone technology combined with data science has the potential to offer medicine a wealth of additional information on disease phenotypes, but the large majority of existing smartphone apps are not intended for use as biomedical research platforms and, as such, do not generate research-quality data. Our aim is not the creation of yet another app per se but rather the establishment of a platform to collect research-quality smartphone raw sensor and usage pattern data. Our ultimate goal is to develop statistical, mathematical, and computational methodology to enable us and others to extract biomedical and clinical insights from smartphone data. We report on the development and early testing of Beiwe, a research platform featuring a study portal, smartphone app, database, and data modeling and analysis tools designed and developed specifically for transparent, customizable, and reproducible biomedical research use, in particular for the study of psychiatric and neurological disorders. We also outline a proposed study using the platform for patients with schizophrenia. We demonstrate the passive data capabilities of the Beiwe platform and early results of its analytical capabilities. Smartphone sensors and phone usage patterns, when coupled with appropriate statistical learning tools, are able to capture various social and behavioral manifestations of illnesses, in naturalistic settings, as lived and experienced by patients. The ubiquity of smartphones makes this type of moment-by-moment quantification of disease phenotypes highly scalable and, when integrated within a transparent research platform, presents tremendous opportunities for research, discovery, and patient health.

  20. Action-research platforms in water and agriculture: Lessons from three programmes in Africa

    CSIR Research Space (South Africa)

    Tucker, J

    2013-05-01

    Full Text Available Stakeholder platforms are popular among agricultural innovation projects. However, there has been limited critical or comparative research on these platforms, exploring what outcomes can be expected and what makes platforms effective or sustainable...

  1. Raven-II: an open platform for surgical robotics research.

    Science.gov (United States)

    Hannaford, Blake; Rosen, Jacob; Friedman, Diana W; King, Hawkeye; Roan, Phillip; Cheng, Lei; Glozman, Daniel; Ma, Ji; Kosari, Sina Nia; White, Lee

    2013-04-01

    The Raven-II is a platform for collaborative research on advances in surgical robotics. Seven universities have begun research using this platform. The Raven-II system has two 3-DOF spherical positioning mechanisms capable of attaching interchangeable four DOF instruments. The Raven-II software is based on open standards such as Linux and ROS to maximally facilitate software development. The mechanism is robust enough for repeated experiments and animal surgery experiments, but is not engineered to sufficient safety standards for human use. Mechanisms in place for interaction among the user community and dissemination of results include an electronic forum, an online software SVN repository, and meetings and workshops at major robotics conferences.

  2. Health Information Research Platform (HIReP)--an architecture pattern.

    Science.gov (United States)

    Schreiweis, Björn; Schneider, Gerd; Eichner, Theresia; Bergh, Björn; Heinze, Oliver

    2014-01-01

    Secondary use or single source is still far from routine in healthcare, although lots of data are available either structured or unstructured. As data are stored in multiple systems, using them for biomedical research is difficult. Clinical data warehouses already help overcoming this issue, but currently they are only used for certain parts of biomedical research. A comprehensive research platform based on a generic architecture pattern could increase the benefits of existing data warehouses for both patient care and research by meeting two objectives: serving as a so called single point-of-truth and acting as a mediator between them strengthening interaction and close collaboration. Another effect is to reduce boundaries for the implementation of data warehouses. Taking further settings into account the architecture of a clinical data warehouse supporting patient care and biomedical research needs to be integrated with biomaterial banks and other sources. This work provides a solution conceptualizing a comprehensive architecture pattern of a Health Information Research Platform (HIReP) derived from use cases of the patient care and biomedical research domain. It serves as single IT infrastructure providing solutions for any type of use case.

  3. Semantic Web-Based Services for Supporting Voluntary Collaboration among Researchers Using an Information Dissemination Platform

    Directory of Open Access Journals (Sweden)

    Hanmin Jung

    2007-05-01

    Full Text Available Information dissemination platforms for supporting voluntary collaboration among researchers should assure that controllable and verified information is being disseminated. However, previous related studies on this field narrowed their research scopes into information type and information specification. This paper focuses on the verification and the tracing of information using an information dissemination platform and other Semantic Web-based services. Services on our platform include information dissemination services to support reliable information exchange among researchers and knowledge service to provide unrevealed information. The latter is also divided into the two: knowledgization using ontology and inference using a Semantic Web-based inference engine. This paper discusses how this platform supports instant knowledge addition and inference. We demonstrate our approach by constructing an ontology for national R&D reference information using 37,656 RDF triples from about 2,300 KISTI (Korea Institute of Science and Technology Information outcomes. Three knowledge services including 'Communities of Practice', 'Researcher Tracing,' and 'Research Map' were implemented on our platform using a Jena framework. Our study shows that information dissemination platforms will make a meaningful contribution to the possibility of realizing a practical Semantic Web-based information dissemination platform.

  4. European research platform IPANEMA at the SOLEIL synchrotron for ancient and historical materials

    International Nuclear Information System (INIS)

    Bertrand, L.; Languille, M.A.; Cohen, S.X.; Robinet, L.; Josse, W.; Gervais, C.; Leroy, S.; Bernard, D.; Le Pennec, E.; Doucet, J.; Schoder, S.

    2011-01-01

    IPANEMA, a research platform devoted to ancient and historical materials (archaeology, cultural heritage, palaeontology and past environments), is currently being set up at the synchrotron facility SOLEIL (Saint-Aubin, France; SOLEIL opened to users in January 2008). The new platform is open to French, European and international users. The activities of the platform are centred on two main fields: increased support to synchrotron projects on ancient materials and methodological research. The IPANEMA team currently occupies temporary premises at SOLEIL, but the platform comprises construction of a new building that will comply with conservation and environmental standards and of a hard X-ray imaging beamline today in its conceptual design phase, named PUMA. Since 2008, the team has supported synchrotron works at SOLEIL and at European synchrotron facilities on a range of topics including pigment degradation in paintings, composition of musical instrument varnishes, and provenancing of medieval archaeological ferrous artefacts. Once the platform is fully operational, user support will primarily take place within medium-term research projects for 'hosted' scientists, PhDs and post-docs. IPANEMA methodological research is focused on advanced two-dimensional/ three-dimensional imaging and spectroscopy and statistical image analysis, both optimized for ancient materials. (authors)

  5. A cloud computing based platform for sleep behavior and chronic diseases collaborative research.

    Science.gov (United States)

    Kuo, Mu-Hsing; Borycki, Elizabeth; Kushniruk, Andre; Huang, Yueh-Min; Hung, Shu-Hui

    2014-01-01

    The objective of this study is to propose a Cloud Computing based platform for sleep behavior and chronic disease collaborative research. The platform consists of two main components: (1) a sensing bed sheet with textile sensors to automatically record patient's sleep behaviors and vital signs, and (2) a service-oriented cloud computing architecture (SOCCA) that provides a data repository and allows for sharing and analysis of collected data. Also, we describe our systematic approach to implementing the SOCCA. We believe that the new cloud-based platform can provide nurse and other health professional researchers located in differing geographic locations with a cost effective, flexible, secure and privacy-preserved research environment.

  6. EPOS Thematic Core Service ANTHROPOGENIC HAZARDS (TCS AH) - development of e-research platform

    Science.gov (United States)

    Orlecka-Sikora, Beata

    2017-04-01

    TCS AH is based on IS-EPOS Platform. The Platform facilitates research on anthropogenic hazards and is available online, free of charge https://tcs.ah-epos.eu/. The Platform is a final product of the IS-EPOS project, founded by the national programme - POIG - which was implemented in 2013-2015 (POIG.02.03.00-14-090/13-00). The platform is a result of a joint work of scientific community and industrial partners. Currently, the development of TCS AH is carried under EPOS IP project (H2020-INFRADEV-1-2015-1, INFRADEV-3-2015). Platform is an open virtual access point for researchers and Ph. D. students interested in anthropogenic seismicity and related hazards. This environment is designed to ensure a researcher the maximum possible liberty for experimentation by providing a virtual laboratory, in which the researcher can design own processing streams and process the data integrated on the platform. TCS AH integrates: data and specific high-level services. Data gathered in the so-called "episodes", comprehensively describing a geophysical process, induced or triggered by human technological activity, which, under certain circumstances can become hazardous for people, infrastructure and the environment. 7 sets of seismic, geological and technological data were made available on the Platform. The data come from Poland, Germany, UK and Vietnam, and refer to underground mining, reservoir impoundment, shale gas exploitation and geothermal energy production. The next at least 19 new episodes related to conventional hydrocarbon extraction, reservoir treatment, underground mining and geothermal energy production are being integrated within the framework of EPOS IP project. The heterogeneous multi-disciplinary data (seismic, displacement, geomechanical data, production data etc.) are transformed to unified structures to form integrated and validated datasets. To deal with this various data the problem-oriented services were designed and implemented. The particular attention

  7. SimNEC : research platform for studying human functioning in NCW

    NARCIS (Netherlands)

    Veen, H.A.H.C. van; Graaf, B. de; Essens, P.

    2006-01-01

    SimNEC is TNOÆs grand scheme for experimentally studying human factors issues related to NEC/NCW. The research platform SimNEC consists of multidisciplinary expert teams, long-term research programmes, and a local network of state-of-the-art simulator modules. SimNEC does not focus on technology,

  8. NASA's Platform for Cross-Disciplinary Microchannel Research

    Science.gov (United States)

    Son, Sang Young; Spearing, Scott; Allen, Jeffrey; Monaco, Lisa A.

    2003-01-01

    A team from the Structural Biology group located at the NASA Marshall Space Flight Center in Huntsville, Alabama is developing a platform suitable for cross-disciplinary microchannel research. The original objective of this engineering development effort was to deliver a multi-user flight-certified facility for iterative investigations of protein crystal growth; that is, Iterative Biological Crystallization (IBC). However, the unique capabilities of this facility are not limited to the low-gravity structural biology research community. Microchannel-based research in a number of other areas may be greatly accelerated through use of this facility. In particular, the potential for gas-liquid flow investigations and cellular biological research utilizing the exceptional pressure control and simplified coupling to macroscale diagnostics inherent in the IBC facility will be discussed. In conclusion, the opportunities for research-specific modifications to the microchannel configuration, control, and diagnostics will be discussed.

  9. West African Platform for HIV Intervention Research (WAPHIR ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    West African Platform for HIV Intervention Research (WAPHIR) : plateforme de recherche interventionnelle en matière de VIH en Afrique de l'Ouest. Grâce à cette subvention, on appuiera l'établissement d'un partenariat dirigé par des Africains de l'Ouest, en collaboration avec des partenaires canadiens et européens, afin ...

  10. [Platforms are needed for innovative basic research in ophthalmology].

    Science.gov (United States)

    Wang, Yi-qiang

    2012-07-01

    Basic research poses the cornerstone of technical innovation in all lines including medical sciences. Currently, there are shortages of professional scientists as well as technical supporting teams and facilities in the field of basic research of ophthalmology and visual science in China. Evaluation system and personnel policies are not supportive for innovative but high-risk-of-failure research projects. Discussion of reasons and possible solutions are given here to address these problems, aiming at promoting buildup of platforms hosting novel and important basic research in eye science in this country.

  11. Design of e-Science platform for biomedical imaging research cross multiple academic institutions and hospitals

    Science.gov (United States)

    Zhang, Jianguo; Zhang, Kai; Yang, Yuanyuan; Ling, Tonghui; Wang, Tusheng; Wang, Mingqing; Hu, Haibo; Xu, Xuemin

    2012-02-01

    More and more image informatics researchers and engineers are considering to re-construct imaging and informatics infrastructure or to build new framework to enable multiple disciplines of medical researchers, clinical physicians and biomedical engineers working together in a secured, efficient, and transparent cooperative environment. In this presentation, we show an outline and our preliminary design work of building an e-Science platform for biomedical imaging and informatics research and application in Shanghai. We will present our consideration and strategy on designing this platform, and preliminary results. We also will discuss some challenges and solutions in building this platform.

  12. e-Science platform for translational biomedical imaging research: running, statistics, and analysis

    Science.gov (United States)

    Wang, Tusheng; Yang, Yuanyuan; Zhang, Kai; Wang, Mingqing; Zhao, Jun; Xu, Lisa; Zhang, Jianguo

    2015-03-01

    In order to enable multiple disciplines of medical researchers, clinical physicians and biomedical engineers working together in a secured, efficient, and transparent cooperative environment, we had designed an e-Science platform for biomedical imaging research and application cross multiple academic institutions and hospitals in Shanghai and presented this work in SPIE Medical Imaging conference held in San Diego in 2012. In past the two-years, we implemented a biomedical image chain including communication, storage, cooperation and computing based on this e-Science platform. In this presentation, we presented the operating status of this system in supporting biomedical imaging research, analyzed and discussed results of this system in supporting multi-disciplines collaboration cross-multiple institutions.

  13. BioXmark for high-precision radiotherapy in an orthotopic pancreatic tumor mouse model. Experiences with a liquid fiducial marker

    International Nuclear Information System (INIS)

    Dobiasch, S.; Kampfer, S.; Burkhardt, R.; Wilkens, J.J.; Schilling, D.; Schmid, T.E.; Combs, S.E.

    2017-01-01

    High-precision radiotherapy (RT) requires precise positioning, particularly with high single doses. Fiducial markers in combination with onboard imaging are excellent tools to support this. The purpose of this study is to establish a pancreatic cancer mouse model for high-precision image-guided RT (IGRT) using the liquid fiducial marker BioXmark (Nanovi, Kongens Lyngby, Denmark). In an animal-based cancer model, different volumes of BioXmark (10-50 μl), application forms, and imaging modalities - cone-beam computer tomography (CBCT) incorporated in either the Small Animal Radiation Research Platform (SARRP) or the small-animal micro-CT Scanner (SkyScan; Bruker, Brussels, Belgium) - as well as subsequent RT with the SARRP system were analyzed to derive recommendations for BioXmark. Even small volumes (10 μl) of BioXmark could be detected by CBCT (SARRP and Skyscan). Larger volumes (50 μl) led to hardening artefacts. The position of BioXmark was monitored at least weekly by CBCT and was stable over 4 months. BioXmark was shown to be well tolerated; no changes in physical condition or toxic side effects were observed in comparison to control mice. BioXmark enabled an exact fusion with the original treatment plan with less hardening artefacts, and minimized the application of contrast agent for fractionated RT. An orthotopic pancreatic tumor mouse model was established for high-precision IGRT using a fiducial marker. BioXmark was successfully tested and provides the perfect basis for improved imaging in high-precision RT. BioXmark enables a unique application method and optimal targeted precision in fractionated RT. Therefore, preclinical trials evaluating novel fractionation regimens and/or combination treatment with high-end RT can be performed. (orig.) [de

  14. Towards A Research Agenda on Digital Platform Disruption

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    Digital platforms are disruptive IT artifacts, because they facilitate the quick release of innovative platform derivatives from third parties. This study endeavors to unravel the disruptive potential, caused by distinct designs and configurations of digital platforms on market environments. We...... postulate that the disruptive potential of digital platforms is determined by the degree of alignment among the business, technology and platform profiles. Furthermore, we argue that the design and configuration of the aforementioned three elements dictates the extent to which open innovation is permitted....... To shed light on the disruptive potential of digital platforms, we opted for digital payment platforms as our unit of analysis. Through interviews with experts and payment providers, we seek to gain an in-depth appreciation of how contemporary digital payment platforms are designed and configured...

  15. The Doktabörse – an innovative online platform for research projects at the medical faculty of the LMU Munich

    Directory of Open Access Journals (Sweden)

    Nicolai, Leo

    2017-08-01

    Full Text Available Introduction: One of the most important extracurricular aspects of medical studies in Germany is a research thesis completed by most students. This research project often times conveys relevant competencies for the physician’s role as scientist. Nevertheless, the choice of the right project remains a challenge. Reasons for this are among others, missing structures for a comprehensive overview of research groups and their respective projects.Description of the project: We developed the online platform as an online marketplace for doctoral research projects. The platform enables authorized researchers to create working groups and upload, deactivate and change research projects within their institute. For interested students, a front end with integrated search function displays these projects in a structured and well-arranged way. In parallel, the provides for a comprehensive overview of research at the medical faculty. We evaluated Researchers‘ and students‘ use of the platform. Results: 96,6% of students participating in the evaluation (n=400 were in favor of a centralized research platform at the medical faculty. The platform grew at a steady pace and included 120 research groups in June 2016. The students appreciated the structure and design of the Two thirds of all uploaded projects matched successfully with doctoral students via the platform and over 94% of researchers stated that they did not need technical assistance with uploading projects and handling the platform. Discussion: The represents an innovative and well accepted platform for doctoral research projects. The platform is perceived positively by researchers and students alike. However, students criticized limited extent and timeliness of offered projects.In addition, the platform serves as databank of research at the medical faculty of the LMU Munich. The future potential of this platform is to provide for an integrated management solution of doctoral thesis projects

  16. Issues in offshore platform research - Part 1: Semi-submersibles

    Science.gov (United States)

    Sharma, R.; Kim, Tae-Wan; Sha, O. P.; Misra, S. C.

    2010-09-01

    Availability of economic and efficient energy resources is crucial to a nation's development. Because of their low cost and advancement in drilling and exploration technologies, oil and gas based energy systems are the most widely used energy source throughout the world. The inexpensive oil and gas based energy systems are used for everything, i.e., from transportation of goods and people to the harvesting of crops for food. As the energy demand continues to rise, there is strong need for inexpensive energy solutions. An offshore platform is a large structure that is used to house workers and machinery needed to drill wells in the ocean bed, extract oil and/or natural gas, process the produced fluids, and ship or pipe them to shore. Depending on the circumstances, the offshore platform can be fixed (to the ocean floor) or can consist of an artificial island or can float. Semi-submersibles are used for various purposes in offshore and marine engineering, e.g. crane vessels, drilling vessels, tourist vessels, production platforms and accommodation facilities, etc. The challenges of deepwater drilling have further motivated the researchers to design optimum choices for semi-submersibles for a chosen operating depth. In our series of eight papers, we discuss the design and production aspects of all the types of offshore platforms. In the present part I, we present an introduction and critical analysis of semi-submersibles.

  17. The Research of China's Civil Aviation Passenger Multi-Channel Service Technology Platform

    Science.gov (United States)

    Zhibing, Xue; Xinming, Wang

    IATA is promoting Simplifying the Business. The traditional passenger services and business process, such as ticketing, airport counters, had a great influence. The airlines have the passenger service and convenience as the next product development requirements. With civil aviation industry and their company's products construction, the authors propose a solution of passenger multi-channel service product platform. The solution is to streamline the business as the breakthrough point, around the convenience of passengers travel services to travelers as the center, using the current mainstream and the latest IT technology to establish passenger service product platform. The solution will promote DCS e-ticketing business development and service channel diversity. In this paper, the research results have been applied in the product platform construction of the authors' company. The practice shows that through traditional business with the latest IT technologies, traditional passenger services into the emerging service model, passenger service product platform has strong advantages and characteristics. Based on the platform, various types of service products is growing rapidly.

  18. Systematic calibration of an integrated x-ray and optical tomography system for preclinical radiation research

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Yidong, E-mail: yidongyang@med.miami.edu [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231 and Department of Radiation Oncology, University of Miami School of Medicine, Miami, Florida 33136 (United States); Wang, Ken Kang-Hsin; Wong, John W. [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231 (United States); Eslami, Sohrab; Iordachita, Iulian I. [Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, Maryland 21218 (United States); Patterson, Michael S. [Juravinski Cancer Centre and Department of Medical Physics and Applied Radiation Sciences, McMaster University, Hamilton, Ontario L8S4K1 (Canada)

    2015-04-15

    Purpose: The cone beam computed tomography (CBCT) guided small animal radiation research platform (SARRP) has been developed for focal tumor irradiation, allowing laboratory researchers to test basic biological hypotheses that can modify radiotherapy outcomes in ways that were not feasible previously. CBCT provides excellent bone to soft tissue contrast, but is incapable of differentiating tumors from surrounding soft tissue. Bioluminescence tomography (BLT), in contrast, allows direct visualization of even subpalpable tumors and quantitative evaluation of tumor response. Integration of BLT with CBCT offers complementary image information, with CBCT delineating anatomic structures and BLT differentiating luminescent tumors. This study is to develop a systematic method to calibrate an integrated CBCT and BLT imaging system which can be adopted onboard the SARRP to guide focal tumor irradiation. Methods: The integrated imaging system consists of CBCT, diffuse optical tomography (DOT), and BLT. The anatomy acquired from CBCT and optical properties acquired from DOT serve as a priori information for the subsequent BLT reconstruction. Phantoms were designed and procedures were developed to calibrate the CBCT, DOT/BLT, and the entire integrated system. Geometrical calibration was performed to calibrate the CBCT system. Flat field correction was performed to correct the nonuniform response of the optical imaging system. Absolute emittance calibration was performed to convert the camera readout to the emittance at the phantom or animal surface, which enabled the direct reconstruction of the bioluminescence source strength. Phantom and mouse imaging were performed to validate the calibration. Results: All calibration procedures were successfully performed. Both CBCT of a thin wire and a euthanized mouse revealed no spatial artifact, validating the accuracy of the CBCT calibration. The absolute emittance calibration was validated with a 650 nm laser source, resulting in a 3

  19. Systematic calibration of an integrated x-ray and optical tomography system for preclinical radiation research

    International Nuclear Information System (INIS)

    Yang, Yidong; Wang, Ken Kang-Hsin; Wong, John W.; Eslami, Sohrab; Iordachita, Iulian I.; Patterson, Michael S.

    2015-01-01

    Purpose: The cone beam computed tomography (CBCT) guided small animal radiation research platform (SARRP) has been developed for focal tumor irradiation, allowing laboratory researchers to test basic biological hypotheses that can modify radiotherapy outcomes in ways that were not feasible previously. CBCT provides excellent bone to soft tissue contrast, but is incapable of differentiating tumors from surrounding soft tissue. Bioluminescence tomography (BLT), in contrast, allows direct visualization of even subpalpable tumors and quantitative evaluation of tumor response. Integration of BLT with CBCT offers complementary image information, with CBCT delineating anatomic structures and BLT differentiating luminescent tumors. This study is to develop a systematic method to calibrate an integrated CBCT and BLT imaging system which can be adopted onboard the SARRP to guide focal tumor irradiation. Methods: The integrated imaging system consists of CBCT, diffuse optical tomography (DOT), and BLT. The anatomy acquired from CBCT and optical properties acquired from DOT serve as a priori information for the subsequent BLT reconstruction. Phantoms were designed and procedures were developed to calibrate the CBCT, DOT/BLT, and the entire integrated system. Geometrical calibration was performed to calibrate the CBCT system. Flat field correction was performed to correct the nonuniform response of the optical imaging system. Absolute emittance calibration was performed to convert the camera readout to the emittance at the phantom or animal surface, which enabled the direct reconstruction of the bioluminescence source strength. Phantom and mouse imaging were performed to validate the calibration. Results: All calibration procedures were successfully performed. Both CBCT of a thin wire and a euthanized mouse revealed no spatial artifact, validating the accuracy of the CBCT calibration. The absolute emittance calibration was validated with a 650 nm laser source, resulting in a 3

  20. Issues in offshore platform research - Part 1: Semi-submersibles

    Directory of Open Access Journals (Sweden)

    R. Sharma

    2010-09-01

    Full Text Available Availability of economic and efficient energy resources is crucial to a nation's development. Because of their low cost and advancement in drilling and exploration technologies, oil and gas based energy systems are the most widely used energy source throughout the world. The inexpensive oil and gas based energy systems are used for everything, i.e., from transportation of goods and people to the harvesting of crops for food. As the energy demand continues to rise, there is strong need for inexpensive energy solutions. An offshore platform is a large structure that is used to house workers and machinery needed to drill wells in the ocean bed, extract oil and/or natural gas, process the produced fluids, and ship or pipe them to shore. Depending on the circumstances, the offshore platform can be fixed (to the ocean floor or can consist of an artificial island or can float. Semi-submersibles are used for various purposes in offshore and marine engineering, e.g. crane vessels, drilling vessels, tourist vessels, production platforms and accommodation facilities, etc. The challenges of deepwater drilling have further motivated the researchers to design optimum choices for semi-submersibles for a chosen operating depth. In our series of eight papers, we discuss the design and production aspects of all the types of offshore platforms. In the present part I, we present an introduction and critical analysis of semi-submersibles.

  1. Research and application of mobile teaching platform

    Science.gov (United States)

    Yang, Ping; Xue, Hongjiao

    2017-08-01

    The application of mobile technology in university digital campus is ripe. This article mainly introduced the necessity of teaching platform based on mobile Internet in the teaching of higher vocational education, and the key to the construction of the feasibility of mobile learning platform, which is a feasible and effective teaching model under the new situation, worthy of promotion. The design and application of teaching platform based on mobile Internet is the change of educational ideas and working methods, and is the new starting point of Higher Vocational education.

  2. RMS: a platform for managing cross-disciplinary and multi-institutional research project collaboration.

    Science.gov (United States)

    Luo, Jake; Apperson-Hansen, Carolyn; Pelfrey, Clara M; Zhang, Guo-Qiang

    2014-11-30

    Cross-institutional cross-disciplinary collaboration has become a trend as researchers move toward building more productive and innovative teams for scientific research. Research collaboration is significantly changing the organizational structure and strategies used in the clinical and translational science domain. However, due to the obstacles of diverse administrative structures, differences in area of expertise, and communication barriers, establishing and managing a cross-institutional research project is still a challenging task. We address these challenges by creating an integrated informatics platform to reduce the barriers to biomedical research collaboration. The Request Management System (RMS) is an informatics infrastructure designed to transform a patchwork of expertise and resources into an integrated support network. The RMS facilitates investigators' initiation of new collaborative projects and supports the management of the collaboration process. In RMS, experts and their knowledge areas are categorized and managed structurally to provide consistent service. A role-based collaborative workflow is tightly integrated with domain experts and services to streamline and monitor the life-cycle of a research project. The RMS has so far tracked over 1,500 investigators with over 4,800 tasks. The research network based on the data collected in RMS illustrated that the investigators' collaborative projects increased close to 3 times from 2009 to 2012. Our experience with RMS indicates that the platform reduces barriers for cross-institutional collaboration of biomedical research projects. Building a new generation of infrastructure to enhance cross-disciplinary and multi-institutional collaboration has become an important yet challenging task. In this paper, we share the experience of developing and utilizing a collaborative project management system. The results of this study demonstrate that a web-based integrated informatics platform can facilitate and

  3. A method for establishing a long duration, stratospheric platform for astronomical research

    Science.gov (United States)

    Fesen, Robert; Brown, Yorke

    2015-10-01

    During certain times of the year at middle and low latitudes, winds in the upper stratosphere move in nearly the opposite direction than the wind in the lower stratosphere. Here we present a method for maintaining a high-altitude balloon platform in near station-keeping mode that utilizes this stratospheric wind shear. The proposed method places a balloon-borne science platform high in the stratosphere connected by a lightweight, high-strength tether to a tug vehicle located in the lower or middle stratosphere. Using aerodynamic control surfaces, wind-induced aerodynamic forces on the tug can be manipulated to counter the wind drag acting on the higher altitude science vehicle, thus controlling the upper vehicle's geographic location. We describe the general framework of this station-keeping method, some important properties required for the upper stratospheric science payload and lower tug platforms, and compare this station-keeping approach with the capabilities of a high altitude airship and conventional tethered aerostat approaches. We conclude by discussing the advantages of such a platform for a variety of missions with emphasis on astrophysical research.

  4. A Binaural CI Research Platform for Oticon Medical SP/XP Implants Enabling ITD/ILD and Variable Rate Processing

    Science.gov (United States)

    Adiloğlu, K.; Herzke, T.

    2015-01-01

    We present the first portable, binaural, real-time research platform compatible with Oticon Medical SP and XP generation cochlear implants. The platform consists of (a) a pair of behind-the-ear devices, each containing front and rear calibrated microphones, (b) a four-channel USB analog-to-digital converter, (c) real-time PC-based sound processing software called the Master Hearing Aid, and (d) USB-connected hardware and output coils capable of driving two implants simultaneously. The platform is capable of processing signals from the four microphones simultaneously and producing synchronized binaural cochlear implant outputs that drive two (bilaterally implanted) SP or XP implants. Both audio signal preprocessing algorithms (such as binaural beamforming) and novel binaural stimulation strategies (within the implant limitations) can be programmed by researchers. When the whole research platform is combined with Oticon Medical SP implants, interaural electrode timing can be controlled on individual electrodes to within ±1 µs and interaural electrode energy differences can be controlled to within ±2%. Hence, this new platform is particularly well suited to performing experiments related to interaural time differences in combination with interaural level differences in real-time. The platform also supports instantaneously variable stimulation rates and thereby enables investigations such as the effect of changing the stimulation rate on pitch perception. Because the processing can be changed on the fly, researchers can use this platform to study perceptual changes resulting from different processing strategies acutely. PMID:26721923

  5. A Binaural CI Research Platform for Oticon Medical SP/XP Implants Enabling ITD/ILD and Variable Rate Processing.

    Science.gov (United States)

    Backus, B; Adiloğlu, K; Herzke, T

    2015-12-30

    We present the first portable, binaural, real-time research platform compatible with Oticon Medical SP and XP generation cochlear implants. The platform consists of (a) a pair of behind-the-ear devices, each containing front and rear calibrated microphones, (b) a four-channel USB analog-to-digital converter, (c) real-time PC-based sound processing software called the Master Hearing Aid, and (d) USB-connected hardware and output coils capable of driving two implants simultaneously. The platform is capable of processing signals from the four microphones simultaneously and producing synchronized binaural cochlear implant outputs that drive two (bilaterally implanted) SP or XP implants. Both audio signal preprocessing algorithms (such as binaural beamforming) and novel binaural stimulation strategies (within the implant limitations) can be programmed by researchers. When the whole research platform is combined with Oticon Medical SP implants, interaural electrode timing can be controlled on individual electrodes to within ±1 µs and interaural electrode energy differences can be controlled to within ±2%. Hence, this new platform is particularly well suited to performing experiments related to interaural time differences in combination with interaural level differences in real-time. The platform also supports instantaneously variable stimulation rates and thereby enables investigations such as the effect of changing the stimulation rate on pitch perception. Because the processing can be changed on the fly, researchers can use this platform to study perceptual changes resulting from different processing strategies acutely. © The Author(s) 2015.

  6. Platform Performance and Challenges - using Platforms in Lego Company

    DEFF Research Database (Denmark)

    Munk, Lone; Mortensen, Niels Henrik

    2009-01-01

    needs focus on the incentive of using the platform. This problem lacks attention in literature, as well as industry, where assessment criteria do not cover this aspect. Therefore, we recommend including user incentive in platform assessment criteria to these challenges. Concrete solution elements...... ensuring user incentive in platforms is an object for future research...

  7. PARAMO: a PARAllel predictive MOdeling platform for healthcare analytic research using electronic health records.

    Science.gov (United States)

    Ng, Kenney; Ghoting, Amol; Steinhubl, Steven R; Stewart, Walter F; Malin, Bradley; Sun, Jimeng

    2014-04-01

    Healthcare analytics research increasingly involves the construction of predictive models for disease targets across varying patient cohorts using electronic health records (EHRs). To facilitate this process, it is critical to support a pipeline of tasks: (1) cohort construction, (2) feature construction, (3) cross-validation, (4) feature selection, and (5) classification. To develop an appropriate model, it is necessary to compare and refine models derived from a diversity of cohorts, patient-specific features, and statistical frameworks. The goal of this work is to develop and evaluate a predictive modeling platform that can be used to simplify and expedite this process for health data. To support this goal, we developed a PARAllel predictive MOdeling (PARAMO) platform which (1) constructs a dependency graph of tasks from specifications of predictive modeling pipelines, (2) schedules the tasks in a topological ordering of the graph, and (3) executes those tasks in parallel. We implemented this platform using Map-Reduce to enable independent tasks to run in parallel in a cluster computing environment. Different task scheduling preferences are also supported. We assess the performance of PARAMO on various workloads using three datasets derived from the EHR systems in place at Geisinger Health System and Vanderbilt University Medical Center and an anonymous longitudinal claims database. We demonstrate significant gains in computational efficiency against a standard approach. In particular, PARAMO can build 800 different models on a 300,000 patient data set in 3h in parallel compared to 9days if running sequentially. This work demonstrates that an efficient parallel predictive modeling platform can be developed for EHR data. This platform can facilitate large-scale modeling endeavors and speed-up the research workflow and reuse of health information. This platform is only a first step and provides the foundation for our ultimate goal of building analytic pipelines

  8. Platform Constellations

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2016-01-01

    This research paper presents an initial attempt to introduce and explain the emergence of new phenomenon, which we refer to as platform constellations. Functioning as highly modular systems, the platform constellations are collections of highly connected platforms which co-exist in parallel and a......’ acquisition and users’ engagement rates as well as unlock new sources of value creation and diversify revenue streams....

  9. The RUDY study platform – a novel approach to patient driven research in rare musculoskeletal diseases

    Directory of Open Access Journals (Sweden)

    M. K. Javaid

    2016-11-01

    Full Text Available Abstract Background Research into rare diseases is becoming more common, with recognition of the significant diagnostic and therapeutic care gaps. Registries are considered a key research methodology to address rare diseases. This report describes the structure of the Rare UK Diseases Study (RUDY platform that aims to improve research processes and address many of the challenges of carrying out rare musculoskeletal disease research. RUDY is an internet-based platform with online registration, initial verbal consent, online capture of patient reported outcome measures and events within a dynamic consent framework. The database structure, security and governance framework are described. Results There have been 380 participants recruited into RUDY with completed questionnaire rates in excess of 50 %. There has been one withdrawal and two participants have amended their consent options. Conclusions The strengths of RUDY include low burden for the clinical team, low research administration costs with high participant recruitment and ease of data collection and access. This platform has the potential to be used as the model for other rare diseases globally.

  10. Research and development of common DAQ platform

    International Nuclear Information System (INIS)

    Higuchi, T.; Igarashi, Y.; Nakao, M.; Suzuki, S.Y.; Tanaka, M.; Nagasaka, Y.; Varner, G.

    2003-01-01

    The upgrade of the KEKB accelerator toward L=10 35 cm -2 s -1 requires an upgrade of the Belle data acquisition system. To match the market trend, we develop a DAQ platform based on the PCI bus that enables fastest DAQ with longer lifetime of the system. The platform is a VME-9U motherboard comprising of four slots for signal digitization modules and three PMC slots to house CPU for data compression. The platform is equipped with event FIFOs for data buffering to minimize the dead-time. A trigger module residing on VME-6U size rear board is connected to the 9U board via PCI-PCI bridge to make an interrupt for the CPU upon the level-1 trigger. (author)

  11. New Tools for New Research in Psychiatry: A Scalable and Customizable Platform to Empower Data Driven Smartphone Research

    OpenAIRE

    Torous, John; Kiang, Mathew V; Lorme, Jeanette; Onnela, Jukka-Pekka

    2016-01-01

    Background A longstanding barrier to progress in psychiatry, both in clinical settings and research trials, has been the persistent difficulty of accurately and reliably quantifying disease phenotypes. Mobile phone technology combined with data science has the potential to offer medicine a wealth of additional information on disease phenotypes, but the large majority of existing smartphone apps are not intended for use as biomedical research platforms and, as such, do not generate research-qu...

  12. Dynamic simulation platform to verify the performance of the reactor regulating system for a research reactor

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-07-01

    Digital instrumentation and controls system technique is being introduced in new constructed research reactor or life extension of older research reactor. Digital systems are easy to change and optimize but the validated process for them is required. Also, to reduce project risk or cost, we have to make it sure that configuration and control functions is right before the commissioning phase on research reactor. For this purpose, simulators have been widely used in developing control systems in automotive and aerospace industries. In these literatures, however, very few of these can be found regarding test on the control system of research reactor with simulator. Therefore, this paper proposes a simulation platform to verify the performance of RRS (Reactor Regulating System) for research reactor. This simulation platform consists of the reactor simulation model and the interface module. This simulation platform is applied to I and C upgrade project of TRIGA reactor, and many problems of RRS configuration were found and solved. And it proved that the dynamic performance testing based on simulator enables significant time saving and improves economics and quality for RRS in the system test phase. (authors)

  13. Product Platform Performance

    DEFF Research Database (Denmark)

    Munk, Lone

    The aim of this research is to improve understanding of platform-based product development by studying platform performance in relation to internal effects in companies. Platform-based product development makes it possible to deliver product variety and at the same time reduce the needed resources...... engaging in platform-based product development. Similarly platform assessment criteria lack empirical verification regarding relevance and sufficiency. The thesis focuses on • the process of identifying and estimating internal effects, • verification of performance of product platforms, (i...... experienced representatives from the different life systems phase systems of the platform products. The effects are estimated and modeled within different scenarios, taking into account financial and real option aspects. The model illustrates and supports estimation and quantification of internal platform...

  14. GIFT-Cloud: A data sharing and collaboration platform for medical imaging research.

    Science.gov (United States)

    Doel, Tom; Shakir, Dzhoshkun I; Pratt, Rosalind; Aertsen, Michael; Moggridge, James; Bellon, Erwin; David, Anna L; Deprest, Jan; Vercauteren, Tom; Ourselin, Sébastien

    2017-02-01

    Clinical imaging data are essential for developing research software for computer-aided diagnosis, treatment planning and image-guided surgery, yet existing systems are poorly suited for data sharing between healthcare and academia: research systems rarely provide an integrated approach for data exchange with clinicians; hospital systems are focused towards clinical patient care with limited access for external researchers; and safe haven environments are not well suited to algorithm development. We have established GIFT-Cloud, a data and medical image sharing platform, to meet the needs of GIFT-Surg, an international research collaboration that is developing novel imaging methods for fetal surgery. GIFT-Cloud also has general applicability to other areas of imaging research. GIFT-Cloud builds upon well-established cross-platform technologies. The Server provides secure anonymised data storage, direct web-based data access and a REST API for integrating external software. The Uploader provides automated on-site anonymisation, encryption and data upload. Gateways provide a seamless process for uploading medical data from clinical systems to the research server. GIFT-Cloud has been implemented in a multi-centre study for fetal medicine research. We present a case study of placental segmentation for pre-operative surgical planning, showing how GIFT-Cloud underpins the research and integrates with the clinical workflow. GIFT-Cloud simplifies the transfer of imaging data from clinical to research institutions, facilitating the development and validation of medical research software and the sharing of results back to the clinical partners. GIFT-Cloud supports collaboration between multiple healthcare and research institutions while satisfying the demands of patient confidentiality, data security and data ownership. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  15. The Design:Lab as platform in participatory design research

    DEFF Research Database (Denmark)

    Binder, Thomas; Brandt, Eva

    2008-01-01

    The notion of laboratory or simply 'lab' has become popular in recent years in areas outside science and technology development. Learning Labs, Innovation Labs, Usability Labs, Media and Communication Labs and even Art Labs designate institutions or fora dedicated to change and experimentation...... as others have frequently used other metaphors like workshop, studio or atelier in design research. In this article we will argue that the laboratory metaphor is particularly suitable and useful for the design:lab, and we will give examples of how we have worked with the design:lab as a platform...

  16. Sharing Health Big Data for Research - A Design by Use Cases: The INSHARE Platform Approach.

    Science.gov (United States)

    Bouzillé, Guillaume; Westerlynck, Richard; Defossez, Gautier; Bouslimi, Dalel; Bayat, Sahar; Riou, Christine; Busnel, Yann; Le Guillou, Clara; Cauvin, Jean-Michel; Jacquelinet, Christian; Pladys, Patrick; Oger, Emmanuel; Stindel, Eric; Ingrand, Pierre; Coatrieux, Gouenou; Cuggia, Marc

    2017-01-01

    Sharing and exploiting Health Big Data (HBD) allow tackling challenges: data protection/governance taking into account legal, ethical, and deontological aspects enables trust, transparent and win-win relationship between researchers, citizens, and data providers. Lack of interoperability: compartmentalized and syntactically/semantica heterogeneous data. INSHARE project using experimental proof of concept explores how recent technologies overcome such issues. Using 6 data providers, platform is designed via 3 steps to: (1) analyze use cases, needs, and requirements; (2) define data sharing governance, secure access to platform; and (3) define platform specifications. Three use cases - from 5 studies and 11 data sources - were analyzed for platform design. Governance derived from SCANNER model was adapted to data sharing. Platform architecture integrates: data repository and hosting, semantic integration services, data processing, aggregate computing, data quality and integrity monitoring, Id linking, multisource query builder, visualization and data export services, data governance, study management service and security including data watermarking.

  17. Standardized analysis and sharing of genome-phenome data for neuromuscular and rare disease research through the RD-Connect platform

    OpenAIRE

    Thompson, Rachel; Beltran, Sergi; Papakonstantinou, Anastasios; Cañada, Andrés; Fernández, Jose Maria; Thompson, Mark; Kaliyaperumal, Rajaram; Lair, Séverine; Sernadela, Pedro; Girdea, Marta; Brudno, Michael; Blavier, André; Lochmüller, Hanns; Roos, Andreas; Straub, Volker

    2016-01-01

    Abstract: RD-Connect (rd-connect.eu) is an EU-funded project building an integrated platform to narrow the gaps in rare disease research, where patient populations, clinical expertise and research communities are small in number and highly fragmented. Guided by the needs of rare disease researchers and with neuromuscular and neurodegenerative researchers as its original collaborators, the RD-Connect platform securely integrates multiple types of omics data (genomics, proteomics and transcript...

  18. Thermal-hydraulic uncertainties affecting severe accident progression

    International Nuclear Information System (INIS)

    Haskin, F.E.; Behr, V.L.

    1984-01-01

    To provide the proper technical bases for decisions regarding severe accidents, the US Nuclear Regulatory Commission (NRC) is sponsoring the following activities: (a) a variety of severe accident research programs, combined under the Severe Accident Research Plan; (b) nationwide task forces on containment loading, containment response, and fission product source terms; (c) a review by the American Physical Society of state-of-the-art methods for calculating radiological source terms; and (d) technical exchange meetings with the Industry Degraded Core (IDCOR) program. One of the means for integrating this developing array of technical information is the Severe Accident Risk Reduction Program (SARRP). One of the current SARRP objectives is to utilize insights gained from the activities listed above to characterize the relative likelihoods of competing containment failure modes for core-melt accidents

  19. Development of a Web-Based Visualization Platform for Climate Research Using Google Earth

    Science.gov (United States)

    Sun, Xiaojuan; Shen, Suhung; Leptoukh, Gregory G.; Wang, Panxing; Di, Liping; Lu, Mingyue

    2011-01-01

    Recently, it has become easier to access climate data from satellites, ground measurements, and models from various data centers, However, searching. accessing, and prc(essing heterogeneous data from different sources are very tim -consuming tasks. There is lack of a comprehensive visual platform to acquire distributed and heterogeneous scientific data and to render processed images from a single accessing point for climate studies. This paper. documents the design and implementation of a Web-based visual, interoperable, and scalable platform that is able to access climatological fields from models, satellites, and ground stations from a number of data sources using Google Earth (GE) as a common graphical interface. The development is based on the TCP/IP protocol and various data sharing open sources, such as OPeNDAP, GDS, Web Processing Service (WPS), and Web Mapping Service (WMS). The visualization capability of integrating various measurements into cE extends dramatically the awareness and visibility of scientific results. Using embedded geographic information in the GE, the designed system improves our understanding of the relationships of different elements in a four dimensional domain. The system enables easy and convenient synergistic research on a virtual platform for professionals and the general public, gr$tly advancing global data sharing and scientific research collaboration.

  20. Application Platform for Intelligent Mobility – research facility for intelligent mobility services

    OpenAIRE

    Schnieder, Lars

    2012-01-01

    Traffic can be seen as a multi-dimensional field of research. Traffic can be best described as a socio-technical system which brings about new challenges for the design of future transportation systems. With its Application Platform for Intelligent Mobility (AIM), the German Aerospace Center (DLR), together with the state of Lower Saxony, the city of Braunschweig and other partners, is creating a unique way of linking up research, development and applications for intelligent transportation an...

  1. Central Vehicle Dynamics Control of the Robotic Research Platform ROboMObil

    OpenAIRE

    Bünte, Tilman; Ho, Lok Man; Satzger, Clemens; Brembeck, Jonathan

    2014-01-01

    The ROboMObil is DLR’s space-robotics driven by-wire electro-mobile research platform for mechatronic actuators, vehicle dynamics control, human machine interfaces, and autonomous driving (DLR = German Aerospace Center). Due to its four highly integrated identical Wheel Robots it exhibits an extraordinary manoeuvrability even allowing for driving sideward or rotating on the spot. Topics related to vehicle dynamics control are addressed in this article.

  2. Mobile platform security

    CERN Document Server

    Asokan, N; Dmitrienko, Alexandra

    2013-01-01

    Recently, mobile security has garnered considerable interest in both the research community and industry due to the popularity of smartphones. The current smartphone platforms are open systems that allow application development, also for malicious parties. To protect the mobile device, its user, and other mobile ecosystem stakeholders such as network operators, application execution is controlled by a platform security architecture. This book explores how such mobile platform security architectures work. We present a generic model for mobile platform security architectures: the model illustrat

  3. Development of the Research Platform of Small Autonomous Blimp Robot

    Science.gov (United States)

    Takaya, Toshihiko; Kawamura, Hidenori; Yamamoto, Masahito; Ohuchi, Azuma

    A blimp robot is attractive as an small flight robot and can float in the air by buoyancy and realize safe to the crash small flight with low energy and can movement for a long time compared with other flight robots with low energy and can movement for a long time compared with other flight robots. However, control of an airplane robot is difficult for the nonlinear characteristic exposed to inertia by the air flow in response to influence. Therefore, the applied research which carried out the maximum use of such in recent years a blimp robot's feature is prosperous. In this paper, we realized development of blimp robot for research which can be used general-purpose by carrying out clue division of the blimp robot body at a unit, and constituting and building for research of blimp robot, and application development. On the other hand, by developing a general-purpose blimp robot research platform, improvement in the research efficiency of many researchers can be attained, and further, research start of blimp robot becomes easy and contributes to development of research. We performed the experiments for the above-mentioned proof. 1. Checked basic keeping position performance and that various orbital operation was possible. And the unit exchange ease of software unit was checked by the experiment which exchanges the control layer of software for learning control from PID control, and carries out comparison of operation. 2. In order to check the exchange ease of hardware unit, the sensor was exchanged for the microphon from the camera, and control of operation was checked. 3. For the unit addition ease, the microphon which carries out sound detection with the picture detection with a camera was added, and control of operation was verified. 4. The unit exchange was carried out for the check of a function addition and the topological map generation experiment by addition of an ultrasonic sensor was conducted. Developed blimp robot for research mounted the exchange ease

  4. Cross-platform learning: on the nature of children's learning from multiple media platforms.

    Science.gov (United States)

    Fisch, Shalom M

    2013-01-01

    It is increasingly common for an educational media project to span several media platforms (e.g., TV, Web, hands-on materials), assuming that the benefits of learning from multiple media extend beyond those gained from one medium alone. Yet research typically has investigated learning from a single medium in isolation. This paper reviews several recent studies to explore cross-platform learning (i.e., learning from combined use of multiple media platforms) and how such learning compares to learning from one medium. The paper discusses unique benefits of cross-platform learning, a theoretical mechanism to explain how these benefits might arise, and questions for future research in this emerging field. Copyright © 2013 Wiley Periodicals, Inc., A Wiley Company.

  5. Launching a virtual decision lab: development and field-testing of a web-based patient decision support research platform.

    Science.gov (United States)

    Hoffman, Aubri S; Llewellyn-Thomas, Hilary A; Tosteson, Anna N A; O'Connor, Annette M; Volk, Robert J; Tomek, Ivan M; Andrews, Steven B; Bartels, Stephen J

    2014-12-12

    Over 100 trials show that patient decision aids effectively improve patients' information comprehension and values-based decision making. However, gaps remain in our understanding of several fundamental and applied questions, particularly related to the design of interactive, personalized decision aids. This paper describes an interdisciplinary development process for, and early field testing of, a web-based patient decision support research platform, or virtual decision lab, to address these questions. An interdisciplinary stakeholder panel designed the web-based research platform with three components: a) an introduction to shared decision making, b) a web-based patient decision aid, and c) interactive data collection items. Iterative focus groups provided feedback on paper drafts and online prototypes. A field test assessed a) feasibility for using the research platform, in terms of recruitment, usage, and acceptability; and b) feasibility of using the web-based decision aid component, compared to performance of a videobooklet decision aid in clinical care. This interdisciplinary, theory-based, patient-centered design approach produced a prototype for field-testing in six months. Participants (n = 126) reported that: the decision aid component was easy to use (98%), information was clear (90%), the length was appropriate (100%), it was appropriately detailed (90%), and it held their interest (97%). They spent a mean of 36 minutes using the decision aid and 100% preferred using their home/library computer. Participants scored a mean of 75% correct on the Decision Quality, Knowledge Subscale, and 74 out of 100 on the Preparation for Decision Making Scale. Completing the web-based decision aid reduced mean Decisional Conflict scores from 31.1 to 19.5 (p development of a web-based patient decision support research platform that was feasible for use in research studies in terms of recruitment, acceptability, and usage. Within this platform, the web

  6. Use of Web 2.0 Social Media Platforms to Promote Community-Engaged Research Dialogs: A Preliminary Program Evaluation

    Science.gov (United States)

    Valdez Soto, Miguel; Bishop, Shawn G; Aase, Lee A; Timimi, Farris K; Montori, Victor M; Patten, Christi A

    2016-01-01

    Background Community-engaged research is defined by the Institute of Medicine as the process of working collaboratively with groups of people affiliated by geographic proximity, special interests, or similar situations with respect to issues affecting their well-being. Traditional face-to-face community-engaged research is limited by geographic location, limited in resources, and/or uses one-way communications. Web 2.0 technologies including social media are novel communication channels for community-engaged research because these tools can reach a broader audience while promoting bidirectional dialogs. Objective This paper reports on a preliminary program evaluation of the use of social media platforms for promoting engagement of researchers and community representatives in dialogs about community-engaged research. Methods For this pilot program evaluation, the Clinical and Translational Science Office for Community Engagement in Research partnered with the Social Media Network at our institution to create a WordPress blog and Twitter account. Both social media platforms were facilitated by a social media manager. We used descriptive analytics for measuring engagement with WordPress and Twitter over an 18-month implementation period during 2014-2016. For the blog, we examined type of user (researcher, community representative, other) and used content analysis to generate the major themes from blog postings. For use of Twitter, we examined selected demographics and impressions among followers. Results There were 76 blog postings observed from researchers (48/76, 64%), community representatives (23/76, 32%) and funders (5/76, 8%). The predominant themes of the blog content were research awareness and dissemination of community-engaged research (35/76, 46%) and best practices (23/76, 30%). For Twitter, we obtained 411 followers at the end of the 18-month evaluation period, with an increase of 42% (from 280 to 411) over the final 6 months. Followers reported varied

  7. Use of Web 2.0 Social Media Platforms to Promote Community-Engaged Research Dialogs: A Preliminary Program Evaluation.

    Science.gov (United States)

    Valdez Soto, Miguel; Balls-Berry, Joyce E; Bishop, Shawn G; Aase, Lee A; Timimi, Farris K; Montori, Victor M; Patten, Christi A

    2016-09-09

    Community-engaged research is defined by the Institute of Medicine as the process of working collaboratively with groups of people affiliated by geographic proximity, special interests, or similar situations with respect to issues affecting their well-being. Traditional face-to-face community-engaged research is limited by geographic location, limited in resources, and/or uses one-way communications. Web 2.0 technologies including social media are novel communication channels for community-engaged research because these tools can reach a broader audience while promoting bidirectional dialogs. This paper reports on a preliminary program evaluation of the use of social media platforms for promoting engagement of researchers and community representatives in dialogs about community-engaged research. For this pilot program evaluation, the Clinical and Translational Science Office for Community Engagement in Research partnered with the Social Media Network at our institution to create a WordPress blog and Twitter account. Both social media platforms were facilitated by a social media manager. We used descriptive analytics for measuring engagement with WordPress and Twitter over an 18-month implementation period during 2014-2016. For the blog, we examined type of user (researcher, community representative, other) and used content analysis to generate the major themes from blog postings. For use of Twitter, we examined selected demographics and impressions among followers. There were 76 blog postings observed from researchers (48/76, 64%), community representatives (23/76, 32%) and funders (5/76, 8%). The predominant themes of the blog content were research awareness and dissemination of community-engaged research (35/76, 46%) and best practices (23/76, 30%). For Twitter, we obtained 411 followers at the end of the 18-month evaluation period, with an increase of 42% (from 280 to 411) over the final 6 months. Followers reported varied geographic location (321/411, 78

  8. EURESCOM Services Platform

    NARCIS (Netherlands)

    Nieuwenhuis, Lambertus Johannes Maria; van Halteren, Aart

    1999-01-01

    This paper presents the results of the EURESCOM Project 715. In February 1999, a large team of researchers from six European public network operators completed a two year period of cooperative experiments on a TINA-based environment, called the EURESCOM Services Platform (ESP). This platform

  9. MyGeoHub: A Collaborative Geospatial Research and Education Platform

    Science.gov (United States)

    Kalyanam, R.; Zhao, L.; Biehl, L. L.; Song, C. X.; Merwade, V.; Villoria, N.

    2017-12-01

    Scientific research is increasingly collaborative and globally distributed; research groups now rely on web-based scientific tools and data management systems to simplify their day-to-day collaborative workflows. However, such tools often lack seamless interfaces, requiring researchers to contend with manual data transfers, annotation and sharing. MyGeoHub is a web platform that supports out-of-the-box, seamless workflows involving data ingestion, metadata extraction, analysis, sharing and publication. MyGeoHub is built on the HUBzero cyberinfrastructure platform and adds general-purpose software building blocks (GABBs), for geospatial data management, visualization and analysis. A data management building block iData, processes geospatial files, extracting metadata for keyword and map-based search while enabling quick previews. iData is pervasive, allowing access through a web interface, scientific tools on MyGeoHub or even mobile field devices via a data service API. GABBs includes a Python map library as well as map widgets that in a few lines of code, generate complete geospatial visualization web interfaces for scientific tools. GABBs also includes powerful tools that can be used with no programming effort. The GeoBuilder tool provides an intuitive wizard for importing multi-variable, geo-located time series data (typical of sensor readings, GPS trackers) to build visualizations supporting data filtering and plotting. MyGeoHub has been used in tutorials at scientific conferences and educational activities for K-12 students. MyGeoHub is also constantly evolving; the recent addition of Jupyter and R Shiny notebook environments enable reproducible, richly interactive geospatial analyses and applications ranging from simple pre-processing to published tools. MyGeoHub is not a monolithic geospatial science gateway, instead it supports diverse needs ranging from just a feature-rich data management system, to complex scientific tools and workflows.

  10. The ASSISTments Ecosystem: Building a Platform That Brings Scientists and Teachers Together for Minimally Invasive Research on Human Learning and Teaching

    Science.gov (United States)

    Heffernan, Neil T.; Heffernan, Cristina Lindquist

    2014-01-01

    The ASSISTments project is an ecosystem of a few hundred teachers, a platform, and researchers working together. Development professionals help train teachers and get teachers to participate in studies. The platform and these teachers help researchers (sometimes explicitly and sometimes implicitly) simply by using content the teacher selects. The…

  11. Designing an Africa-EU research and innovation collaboration platform on climate change

    DEFF Research Database (Denmark)

    Tostensen, Arne; Monteverde Haakonsen, Jan; Hughes, Mike

    Climate change is arguably the most significant of a set of interconnected global challenges threatening water resources and food security. In particular, the relationship between water resources, food systems and climate change is tightly coupled, and improved food security under climate change...... this process more effective by developing a proposition for a platform to strengthen Africa-EU research and innovation collaboration on climate change....

  12. DSF: A Common Platform for Distributed Systems Research and Development

    Science.gov (United States)

    Tang, Chunqiang

    This paper presents Distributed Systems Foundation (DSF), a common platform for distributed systems research and development. It can run a distributed algorithm written in Java under multiple execution modes—simulation, massive multi-tenancy, and real deployment. DSF provides a set of novel features to facilitate testing and debugging, including chaotic timing test and time travel debugging with mutable replay. Unlike existing research prototypes that offer advanced debugging features by hacking programming tools, DSF is written entirely in Java, without modifications to any external tools such as JVM, Java runtime library, compiler, linker, system library, OS, or hypervisor. This simplicity stems from our goal of making DSF not only a research prototype but more importantly a production tool. Experiments show that DSF is efficient and easy to use. DSF's massive multi-tenancy mode can run 4,000 OS-level threads in a single JVM to concurrently execute (as opposed to simulate) 1,000 DHT nodes in real-time.

  13. WiseEye: Next Generation Expandable and Programmable Camera Trap Platform for Wildlife Research.

    Directory of Open Access Journals (Sweden)

    Sajid Nazir

    Full Text Available The widespread availability of relatively cheap, reliable and easy to use digital camera traps has led to their extensive use for wildlife research, monitoring and public outreach. Users of these units are, however, often frustrated by the limited options for controlling camera functions, the generation of large numbers of images, and the lack of flexibility to suit different research environments and questions. We describe the development of a user-customisable open source camera trap platform named 'WiseEye', designed to provide flexible camera trap technology for wildlife researchers. The novel platform is based on a Raspberry Pi single-board computer and compatible peripherals that allow the user to control its functions and performance. We introduce the concept of confirmatory sensing, in which the Passive Infrared triggering is confirmed through other modalities (i.e. radar, pixel change to reduce the occurrence of false positives images. This concept, together with user-definable metadata, aided identification of spurious images and greatly reduced post-collection processing time. When tested against a commercial camera trap, WiseEye was found to reduce the incidence of false positive images and false negatives across a range of test conditions. WiseEye represents a step-change in camera trap functionality, greatly increasing the value of this technology for wildlife research and conservation management.

  14. Dynamic Gaming Platform (DGP)

    Science.gov (United States)

    2009-04-01

    GAMING PLATFORM (DGP) Lockheed Martin Corporation...YYYY) APR 09 2. REPORT TYPE Final 3. DATES COVERED (From - To) Jul 07 – Mar 09 4. TITLE AND SUBTITLE DYNAMIC GAMING PLATFORM (DGP) 5a...CMU Carnegie Mellon University DGP Dynamic Gaming Platform GA Genetic Algorithm IARPA Intelligence Advanced Research Projects Activity LM ATL Lockheed Martin Advanced Technology Laboratories PAINT ProActive INTelligence

  15. Direct2Experts: a pilot national network to demonstrate interoperability among research-networking platforms

    OpenAIRE

    Weber, Griffin M; Barnett, William; Conlon, Mike; Eichmann, David; Kibbe, Warren; Falk-Krzesinski, Holly; Halaas, Michael; Johnson, Layne; Meeks, Eric; Mitchell, Donald; Schleyer, Titus; Stallings, Sarah; Warden, Michael; Kahlon, Maninder

    2011-01-01

    Research-networking tools use data-mining and social networking to enable expertise discovery, matchmaking and collaboration, which are important facets of team science and translational research. Several commercial and academic platforms have been built, and many institutions have deployed these products to help their investigators find local collaborators. Recent studies, though, have shown the growing importance of multiuniversity teams in science. Unfortunately, the lack of a standard dat...

  16. Using online, crowdsourcing platforms for data collection in personality disorder research: The example of Amazon's Mechanical Turk.

    Science.gov (United States)

    Miller, Joshua D; Crowe, Michael; Weiss, Brandon; Maples-Keller, Jessica L; Lynam, Donald R

    2017-01-01

    The use of crowdsourcing platforms such as Amazon's Mechanical Turk (MTurk) for data collection in the behavioral sciences has increased substantially in the past several years due in large part to (a) the ability to recruit large samples, (b) the inexpensiveness of data collection, (c) the speed of data collection, and (d) evidence that the data collected are, for the most part, of equal or better quality to that collected in undergraduate research pools. In this review, we first evaluate the strengths and potential limitations of this approach to data collection. Second, we examine how MTurk has been used to date in personality disorder (PD) research and compare the characteristics of such research to PD research conducted in other settings. Third, we compare PD trait data from the Section III trait model of the DSM-5 collected via MTurk to data collected using undergraduate and clinical samples with regard to internal consistency, mean-level differences, and factor structure. Overall, we conclude that platforms such as MTurk have much to offer PD researchers, especially for certain kinds of research (e.g., where large samples are required and there is a need for iterative sampling). Whether MTurk itself remains the predominant model of such platforms is unclear, however, and will largely depend on decisions related to cost effectiveness and the development of alternatives that offer even greater flexibility. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  17. qPortal: A platform for data-driven biomedical research.

    Science.gov (United States)

    Mohr, Christopher; Friedrich, Andreas; Wojnar, David; Kenar, Erhan; Polatkan, Aydin Can; Codrea, Marius Cosmin; Czemmel, Stefan; Kohlbacher, Oliver; Nahnsen, Sven

    2018-01-01

    Modern biomedical research aims at drawing biological conclusions from large, highly complex biological datasets. It has become common practice to make extensive use of high-throughput technologies that produce big amounts of heterogeneous data. In addition to the ever-improving accuracy, methods are getting faster and cheaper, resulting in a steadily increasing need for scalable data management and easily accessible means of analysis. We present qPortal, a platform providing users with an intuitive way to manage and analyze quantitative biological data. The backend leverages a variety of concepts and technologies, such as relational databases, data stores, data models and means of data transfer, as well as front-end solutions to give users access to data management and easy-to-use analysis options. Users are empowered to conduct their experiments from the experimental design to the visualization of their results through the platform. Here, we illustrate the feature-rich portal by simulating a biomedical study based on publically available data. We demonstrate the software's strength in supporting the entire project life cycle. The software supports the project design and registration, empowers users to do all-digital project management and finally provides means to perform analysis. We compare our approach to Galaxy, one of the most widely used scientific workflow and analysis platforms in computational biology. Application of both systems to a small case study shows the differences between a data-driven approach (qPortal) and a workflow-driven approach (Galaxy). qPortal, a one-stop-shop solution for biomedical projects offers up-to-date analysis pipelines, quality control workflows, and visualization tools. Through intensive user interactions, appropriate data models have been developed. These models build the foundation of our biological data management system and provide possibilities to annotate data, query metadata for statistics and future re-analysis on

  18. A platform for quality management in research institutes (part II

    Directory of Open Access Journals (Sweden)

    Klembalska Agnieszka

    2016-09-01

    Full Text Available In the recent years there has been a particularly strong pressure on changing old structures and management models in research institutes. Contemporary research institutes are scientific units which are commercial in character – almost 80% of funds come from companies and contractual research activity and services. They are the basic sector of science aiming at cooperation with the economy, applied and innovative research. In order to maintain the current and start new cooperation it is necessary to pay particular attention to maintaining, improving and exposing high level of quality of conducted activity. Taking into consideration the necessity of carrying out ever more complex research projects, conducting activity requiring fast reaction to change, risk analysis, which is assessed every year by the Ministry of Science and Higher Education – it seems that it is necessary to apply tools supporting the assessment of quality. In the proposed three-aspect perspective the following scopes of activity are emphasized: implemented quality management systems, area of scientific information and the sphere of cooperation with the client. This article constitutes the continuation of the subjects discussed in the first part – an extension of issues associated with the scope of responsibilities of particular Sections of the proposed Quality Management Platform in research institutes.

  19. A survey of informatics platforms that enable distributed comparative effectiveness research using multi-institutional heterogeneous clinical data

    Science.gov (United States)

    Sittig, Dean F.; Hazlehurst, Brian L.; Brown, Jeffrey; Murphy, Shawn; Rosenman, Marc; Tarczy-Hornoch, Peter; Wilcox, Adam B.

    2012-01-01

    Comparative Effectiveness Research (CER) has the potential to transform the current healthcare delivery system by identifying the most effective medical and surgical treatments, diagnostic tests, disease prevention methods and ways to deliver care for specific clinical conditions. To be successful, such research requires the identification, capture, aggregation, integration, and analysis of disparate data sources held by different institutions with diverse representations of the relevant clinical events. In an effort to address these diverse demands, there have been multiple new designs and implementations of informatics platforms that provide access to electronic clinical data and the governance infrastructure required for inter-institutional CER. The goal of this manuscript is to help investigators understand why these informatics platforms are required and to compare and contrast six, large-scale, recently funded, CER-focused informatics platform development efforts. We utilized an 8-dimension, socio-technical model of health information technology use to help guide our work. We identified six generic steps that are necessary in any distributed, multi-institutional CER project: data identification, extraction, modeling, aggregation, analysis, and dissemination. We expect that over the next several years these projects will provide answers to many important, and heretofore unanswerable, clinical research questions. PMID:22692259

  20. A survey of informatics platforms that enable distributed comparative effectiveness research using multi-institutional heterogenous clinical data.

    Science.gov (United States)

    Sittig, Dean F; Hazlehurst, Brian L; Brown, Jeffrey; Murphy, Shawn; Rosenman, Marc; Tarczy-Hornoch, Peter; Wilcox, Adam B

    2012-07-01

    Comparative effectiveness research (CER) has the potential to transform the current health care delivery system by identifying the most effective medical and surgical treatments, diagnostic tests, disease prevention methods, and ways to deliver care for specific clinical conditions. To be successful, such research requires the identification, capture, aggregation, integration, and analysis of disparate data sources held by different institutions with diverse representations of the relevant clinical events. In an effort to address these diverse demands, there have been multiple new designs and implementations of informatics platforms that provide access to electronic clinical data and the governance infrastructure required for interinstitutional CER. The goal of this manuscript is to help investigators understand why these informatics platforms are required and to compare and contrast 6 large-scale, recently funded, CER-focused informatics platform development efforts. We utilized an 8-dimension, sociotechnical model of health information technology to help guide our work. We identified 6 generic steps that are necessary in any distributed, multi-institutional CER project: data identification, extraction, modeling, aggregation, analysis, and dissemination. We expect that over the next several years these projects will provide answers to many important, and heretofore unanswerable, clinical research questions.

  1. ISS External Payload Platform - a new opportunity for research in the space environment

    Science.gov (United States)

    Steimle, Christian; Pape, Uwe

    The International Space Station (ISS) is a widely accepted platform for research activities in low Earth orbit. To a wide extent these activities are conducted in the pressurised laboratories of the station and less in the outside environment. Suitable locations outside the ISS are rare, existing facilities fully booked for the coming years. To overcome this limitation, an external payload platform accessible for small size payloads on a commercial basis will be launched to the ISS and installed on the Japanese Experiment Module External Facility (JEM-EF) in the third quarter of 2014 and will be ready to be used by the scientific community on a fully commercial basis. The new External Payload Platform (EPP) and its opportunities and constraints assessed regarding future research activities on-board the ISS. The small size platform is realised in a cooperation between the companies NanoRacks, Astrium North America in the United States, and Airbus Defence and Space in Germany. The hardware allows the fully robotic installation and operation of payloads. In the nominal mission scenario payload items are installed not later than one year after the signature of the contract, stay in operation for 15 weeks, and can be returned to the scientist thereafter. Payload items are transported among the pressurised cargo usually delivered to the station with various supply vehicles. Due to the high frequency of flights and the flexibility of the vehicle manifests the risk of a delay in the payload readiness can be mitigated by delaying to the next flight opportunity which on average is available not more than two months later. The mission is extra-ordinarily fast and of low cost in comparison to traditional research conducted on-board the ISS and can fit into short-term funding cycles available on national and multi-national levels. The size of the payload items is limited by handling constraints on-board the ISS. Therefore, the standard experiment payload size is a multiple of a

  2. NEON's Mobile Deployment Platform: A Resource for Community Research

    Science.gov (United States)

    Sanclements, M.

    2015-12-01

    Here we provide an update on construction and validation of the NEON Mobile Deployment Platforms (MDPs) as well as a description of the infrastructure and sensors available to researchers in the future. The MDPs will provide the means to observe stochastic or spatially important events, gradients, or quantities that cannot be reliably observed using fixed location sampling (e.g. fires and floods). Due to the transient temporal and spatial nature of such events, the MDPs will be designed to accommodate rapid deployment for time periods up to ~ 1 year. Broadly, the MDPs will be comprised of infrastructure and instrumentation capable of functioning individually or in conjunction with one another to support observations of ecological change, as well as education, training and outreach.

  3. SenStick: Comprehensive Sensing Platform with an Ultra Tiny All-In-One Sensor Board for IoT Research

    Directory of Open Access Journals (Sweden)

    Yugo Nakamura

    2017-01-01

    Full Text Available We propose a comprehensive sensing platform called SenStick, which is composed of hardware (ultra tiny all-in-one sensor board, software (iOS, Android, and PC, and 3D case data. The platform aims to allow all the researchers to start IoT research, such as activity recognition and context estimation, easily and efficiently. The most important contribution is the hardware that we have designed. Various sensors often used for research are embedded in an ultra tiny board with the size of 50 mm (W × 10 mm (H × 5 mm (D and weight around 3 g including a battery. Concretely, the following sensors are embedded on this board: acceleration, gyro, magnetic, light, UV, temperature, humidity, and pressure. In addition, this board has BLE (Bluetooth low energy connectivity and capability of a rechargeable battery. By using 110 mAh battery, it can run more than 15 hours. The most different point from other similar boards is that our board has a large flash memory for logging all the data without a smartphone. By using SenStick, all the users can collect various data easily and focus on IoT data analytics. In this paper, we introduce SenStick platform and some case studies. Through the user study, we confirmed the usefulness of our proposed platform.

  4. Construction of the Chinese Veteran Clinical Research (CVCR) platform for the assessment of non-communicable diseases.

    Science.gov (United States)

    Tan, Jiping; Li, Nan; Gao, Jing; Guo, Yuhe; Hu, Wei; Yang, Jinsheng; Yu, Baocheng; Yu, Jianmin; Du, Wei; Zhang, Wenjun; Cui, Lianqi; Wang, Qingsong; Xia, Xiangnan; Li, Jianjun; Zhou, Peiyi; Zhang, Baohe; Liu, Zhiying; Zhang, Shaogang; Sun, Lanying; Liu, Nan; Deng, Ruixiang; Dai, Wenguang; Yi, Fang; Chen, Wenjun; Zhang, Yongqing; Xue, Shenwu; Cui, Bo; Zhao, Yiming; Wang, Luning

    2014-01-01

    Based on the excellent medical care and management system for Chinese veterans, as well as the detailed medical documentation available, we aim to construct a Chinese Veteran Clinical Research (CVCR) platform on non-communicable diseases (NCDs) and carry out studies of the primary disabling NCDs. The Geriatric Neurology Department of Chinese People's Liberation Army General Hospital and veterans' hospitals serve as the leading and participating units in the platform construction. The fundamental constituents of the platform are veteran communities. Stratified typical cluster sampling is adopted to recruit veteran communities. A cross-sectional study of mental, neurological, and substance use (MNS) disorders are performed in two stages using screening scale such as the Mini-Mental State Examination and Montreal cognitive assessment, followed by systematic neuropsychological assessments to make clinical diagnoses, evaluated disease awareness and care situation. A total of 9 676 among 277 veteran communities from 18 cities are recruited into this platform, yielding a response rate of 83.86%. 8 812 subjects complete the MNS subproject screening and total response rate is 91.70%. The average participant age is (82.01±4.61) years, 69.47% of veterans are 80 years or older. Most participants are male (94.01%), 83.36% of subjects have at least a junior high school degree. The overall health status of veterans is good and stable. The most common NCD are cardiovascular disorders (86.44%), urinary and genital diseases (73.14%), eye and ear problems (66.25%), endocrine (56.56%) and neuro-psychiatric disturbances (50.78%). We first construct a veterans' comprehensive clinical research platform for the study of NCDs that is primarily composed of highly educated Chinese males of advanced age and utilize this platform to complete a cross-sectional national investigation of MNS disorders among veterans. The good and stable health condition of the veterans could facilitate the long

  5. Storylines as an alternative method to communicate river research via a knowledge platform

    Science.gov (United States)

    Cortes Arevalo, Juliette; Verbrugge, Laura N. H.; den Haan, Robert Jan; Baart, Fedor; Hulscher, Suzanne J. M. H.; van der Voort, Mascha C.

    2017-04-01

    Sustainable river management relies on diverse and multi-faceted knowledge from fundamental and applied research. Communicating the context, added value and potential use of river research to actors working in multiple disciplines or organizations is challenging. RiverCare is a research programme studying the mid-term effects of innovative river interventions in the Netherlands. Effective communication between researchers and potential users of scientific information, such as water professionals, requires an interactive, two-way communication approach. As part of the communication strategy, we are designing a knowledge platform to provide access to, explain and gather feedback about the potential use of results from water professionals. The knowledge platform is a combination of online services including: a content management system in which storylines are the main component; a data repository to the underlying research data and; hyperlinks to existing online sites that present our results via short news articles. Storylines engage water professionals via experiences or stories of river management actors to explain research outputs instead of or in addition to more technical means such as scientific papers and reports. The use of storylines enables us to explain research outcomes in a way that is captivating and easily understood by a multi-disciplinary audience. To explore its usefulness as communication approach, we developed a storyline example for research about stakeholder perceptions of a re-landscaping intervention in the Waal river in the Netherlands. The storyline's layout consisted of a menu outline and three tabs: (1) storyline's content; (2) contact details; and (3) links to available resources or related publications. The storyline's content was divided in four sections including subsections to navigate. Each section had a heading statement or question to engage users: "Imagine this!"; "What matters? Places matter to people"; "Surveying people

  6. NEON's Mobile Deployment Platform: A Resource for Community Research

    Science.gov (United States)

    Sanclements, M.

    2017-12-01

    Here we provide an update on construction of the five NEON Mobile Deployment Platforms (MDPs) as well as a description of the infrastructure and sensors available to researchers in the near future. Additionally, we include information (i.e. timelines and procedures) on requesting MDPs for PI led projects. The MDPs will provide the means to observe stochastic or spatially important events, gradients, or quantities that cannot be reliably observed using fixed location sampling (e.g. fires and floods). Due to the transient temporal and spatial nature of such events, the MDPs are designed to accommodate rapid deployment for time periods up to 1 year. Broadly, the MDPs are comprised of infrastructure and instrumentation capable of functioning individually or in conjunction with one another to support observations of ecological change, as well as education, training and outreach. More specifically, the MDPs include the capability to make tower based measures of ecosystem exchange, radiation, and precipitation in conjunction with baseline soils data such as CO2 flux, and soil temperature and moisture. An aquatics module is also available with the MDP to facilitate research integrating terrestrial and aquatic processes. Ultimately, the NEON MDPs provide a tool for linking PI led research to the continental scale data sets collected by NEON.

  7. Mobile Phone Cognitive Bias Modification Research Platform for Substance Use Disorders: Protocol for a Feasibility Study.

    Science.gov (United States)

    Zhang, Melvyn; Ying, JiangBo; Song, Guo; Fung, Daniel Ss; Smith, Helen

    2018-06-12

    Cognitive biases refer to automatic attentional and interpretational tendencies, which could be retained by cognitive bias modification interventions. Cristea et al and Jones et al have published reviews (in 2016 and 2017 respectively) on the effectiveness of such interventions. The advancement of technologies such as electronic health (eHealth) and mobile health (mHealth) has led to them being harnessed for the delivery of cognitive bias modification. To date, at least eight studies have demonstrated the feasibility of mobile technologies for the delivery of cognitive bias modification. Most of the studies are limited to a description of the conventional cognitive bias modification methodology that has been adopted. None of the studies shared the developmental process for the methodology involved, such that future studies could adopt it in the cost-effective replication of such interventions. It is important to have a common platform that could facilitate the design and customization of cognitive bias modification interventions for a variety of psychiatric and addictive disorders. It is the aim of the current research protocol to describe the design of a research platform that allows for customization of cognitive bias modification interventions for addictive disorders. A multidisciplinary team of 2 addiction psychiatrists, a psychologist with expertise in cognitive bias modification, and a computer engineer, were involved in the development of the intervention. The proposed platform would comprise of a mobile phone version of the cognitive bias task which is controlled by a server that could customize the algorithm for the tasks and collate the reaction-time data in realtime. The server would also allow the researcher to program the specific set of images that will be present in the task. The mobile phone app would synchronize with the backend server in real-time. An open-sourced cross-platform gaming software from React Native was used in the current development

  8. The Data Platform for Climate Research and Action: Introducing Climate Watch

    Science.gov (United States)

    Hennig, R. J.; Ge, M.; Friedrich, J.; Lebling, K.; Carlock, G.; Arcipowska, A.; Mangan, E.; Biru, H.; Tankou, A.; Chaudhury, M.

    2017-12-01

    The Paris Agreement, adopted through Decision 1/CP.21, brings all nations together to take on ambitious efforts to combat climate change. Open access to climate data supporting climate research, advancing knowledge, and informing decision making is key to encourage and strengthen efforts of stakeholders at all levels to address and respond to effects of climate change. Climate Watch is a robust online data platform developed in response to the urgent needs of knowledge and tools to empower climate research and action, including those of researchers, policy makers, the private sector, civil society, and all other non-state actors. Building on the rapid growing technology of open data and information sharing, Climate Watch is equipped with extensive amount of climate data, informative visualizations, concise yet efficient user interface, and connection to resources users need to gather insightful information on national and global progress towards delivering on the objective of the Convention and the Paris Agreement. Climate Watch brings together hundreds of quantitative and qualitative indicators for easy explore, visualize, compare, download at global, national, and sectoral levels: Greenhouse gas (GHG) emissions for more than 190 countries over the1850-2014 time period, covering all seven Kyoto Gases following IPCC source/sink categories; Structured information on over 150 NDCs facilitating the clarity, understanding and transparency of countries' contributions to address climate change; Over 6500 identified linkages between climate actions in NDCs across the 169 targets of the sustainable development goals (SDG); Over 200 indicators describing low carbon pathways from models and scenarios by integrated assessment models (IAMs) and national sources; and Data on vulnerability and risk, policies, finance, and many more. Climate Watch platform is developed as part of the broader efforts within the World Resources Institute, the NDC Partnership, and in collaboration

  9. VASIR: An Open-Source Research Platform for Advanced Iris Recognition Technologies.

    Science.gov (United States)

    Lee, Yooyoung; Micheals, Ross J; Filliben, James J; Phillips, P Jonathon

    2013-01-01

    The performance of iris recognition systems is frequently affected by input image quality, which in turn is vulnerable to less-than-optimal conditions due to illuminations, environments, and subject characteristics (e.g., distance, movement, face/body visibility, blinking, etc.). VASIR (Video-based Automatic System for Iris Recognition) is a state-of-the-art NIST-developed iris recognition software platform designed to systematically address these vulnerabilities. We developed VASIR as a research tool that will not only provide a reference (to assess the relative performance of alternative algorithms) for the biometrics community, but will also advance (via this new emerging iris recognition paradigm) NIST's measurement mission. VASIR is designed to accommodate both ideal (e.g., classical still images) and less-than-ideal images (e.g., face-visible videos). VASIR has three primary modules: 1) Image Acquisition 2) Video Processing, and 3) Iris Recognition. Each module consists of several sub-components that have been optimized by use of rigorous orthogonal experiment design and analysis techniques. We evaluated VASIR performance using the MBGC (Multiple Biometric Grand Challenge) NIR (Near-Infrared) face-visible video dataset and the ICE (Iris Challenge Evaluation) 2005 still-based dataset. The results showed that even though VASIR was primarily developed and optimized for the less-constrained video case, it still achieved high verification rates for the traditional still-image case. For this reason, VASIR may be used as an effective baseline for the biometrics community to evaluate their algorithm performance, and thus serves as a valuable research platform.

  10. Global and Local Path Planning Study in a ROS-Based Research Platform for Autonomous Vehicles

    Directory of Open Access Journals (Sweden)

    Pablo Marin-Plaza

    2018-01-01

    Full Text Available The aim of this work is to integrate and analyze the performance of a path planning method based on Time Elastic Bands (TEB in real research platform based on Ackermann model. Moreover, it will be proved that all modules related to the navigation can coexist and work together to achieve the goal point without any collision. The study is done by analyzing the trajectory generated from global and local planners. The software prototyping tool is Robot Operating System (ROS from Open Source Robotics Foundation and the research platform is the iCab (Intelligent Campus Automobile from University Carlos III. This work has been validated from a test inside the campus where the iCab has performed the navigation between the starting point and the goal point without any collision. During the experiment, we proved the low sensitivity of the TEB method to variations of the vehicle model configuration and constraints.

  11. Platforms.

    Science.gov (United States)

    Josko, Deborah

    2014-01-01

    The advent of DNA sequencing technologies and the various applications that can be performed will have a dramatic effect on medicine and healthcare in the near future. There are several DNA sequencing platforms available on the market for research and clinical use. Based on the medical laboratory scientist or researcher's needs and taking into consideration laboratory space and budget, one can chose which platform will be beneficial to their institution and their patient population. Although some of the instrument costs seem high, diagnosing a patient quickly and accurately will save hospitals money with fewer hospital stays and targeted treatment based on an individual's genetic make-up. By determining the type of disease an individual has, based on the mutations present or having the ability to prescribe the appropriate antimicrobials based on the knowledge of the organism's resistance patterns, the clinician will be better able to treat and diagnose a patient which ultimately will improve patient outcomes and prognosis.

  12. Flexible experimental FPGA based platform

    DEFF Research Database (Denmark)

    Andersen, Karsten Holm; Nymand, Morten

    2016-01-01

    This paper presents an experimental flexible Field Programmable Gate Array (FPGA) based platform for testing and verifying digital controlled dc-dc converters. The platform supports different types of control strategies, dc-dc converter topologies and switching frequencies. The controller platform...... interface supporting configuration and reading of setup parameters, controller status and the acquisition memory in a simple way. The FPGA based platform, provides an easy way within education or research to use different digital control strategies and different converter topologies controlled by an FPGA...

  13. {cross-disciplinary} Data CyberInfrastructure: A Different Approach to Developing Collaborative Earth and Environmental Science Research Platforms

    Science.gov (United States)

    Lenhardt, W. C.; Krishnamurthy, A.; Blanton, B.; Conway, M.; Coposky, J.; Castillo, C.; Idaszak, R.

    2017-12-01

    An integrated science cyberinfrastructure platform is fast becoming a norm in science, particularly where access to distributed resources, access to compute, data management tools, and collaboration tools are accessible to the end-user scientist without the need to spin up these services on their own. There platforms have various types of labels ranging from data commons to science-as-a-service. They tend to share common features, as outlined above. What tends to distinguish these platforms, however, is their affinity for particular domains, NanoHub - nanomaterials, iPlant - plant biology, Hydroshare - hydrology, and so on. The challenge still remains how to enable these platforms to be more easily adopted for use by other domains. This paper will provide an overview of RENCI's approach to creating a science platform that can be more easily adopted by new communities while also endeavoring to accelerate their research. At RENCI, we started with Hydroshare, but have now worked to generalize the methodology for application to other domains. This new effort is called xDCi, or {cross-disciplinary} Data CyberInfrastructure. We have adopted a broader approach to the challenge of domain adoption and includes two key elements in addition to the technology component. The first of these is how development is operationalized. RENCI implements a DevOps model of continuous development and deployment. This greatly increases the speed by which a new platform can come online and be refined to meet domain needs. DevOps also allows for migration over time, i.e. sustainability. The second element is a concierge model. In addition to the technical elements, and the more responsive development process, RENCI also supports domain adoption of the platform by providing a concierge service— dedicated expertise- in the following areas, Information Technology, Sustainable Software, Data Science, and Sustainability. The success of the RENCI methodology is illustrated by the adoption of the

  14. Disentangling Competition Among Platform Driven Strategic Groups

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric

    2015-01-01

    In platform-driven markets, competitive advantage is derived from superior platform design and configurations. For this reason, platform owners strive to create unique and inimitable platform configurals to maintain and extend their competitiveness within network economies. To disentangle firm...... competition within platform-driven markets, we opted for the UK mobile payment market as our empirical setting. By embracing the theoretical lens of strategic groups and digital platforms, this study supplements prior research by deriving a taxonomy of platform-driven strategic groups that is grounded...

  15. Research on vehicles and cargos matching model based on virtual logistics platform

    Science.gov (United States)

    Zhuang, Yufeng; Lu, Jiang; Su, Zhiyuan

    2018-04-01

    Highway less than truckload (LTL) transportation vehicles and cargos matching problem is a joint optimization problem of typical vehicle routing and loading, which is also a hot issue of operational research. This article based on the demand of virtual logistics platform, for the problem of the highway LTL transportation, the matching model of the idle vehicle and the transportation order is set up and the corresponding genetic algorithm is designed. Then the algorithm is implemented by Java. The simulation results show that the solution is satisfactory.

  16. The scheme and research of TV series multidimensional comprehensive evaluation on cross-platform

    Science.gov (United States)

    Chai, Jianping; Bai, Xuesong; Zhou, Hongjun; Yin, Fulian

    2016-10-01

    As for shortcomings of the comprehensive evaluation system on traditional TV programs such as single data source, ignorance of new media as well as the high time cost and difficulty of making surveys, a new evaluation of TV series is proposed in this paper, which has a perspective in cross-platform multidimensional evaluation after broadcasting. This scheme considers the data directly collected from cable television and the Internet as research objects. It's based on TOPSIS principle, after preprocessing and calculation of the data, they become primary indicators that reflect different profiles of the viewing of TV series. Then after the process of reasonable empowerment and summation by the six methods(PCA, AHP, etc.), the primary indicators form the composite indices on different channels or websites. The scheme avoids the inefficiency and difficulty of survey and marking; At the same time, it not only reflects different dimensions of viewing, but also combines TV media and new media, completing the multidimensional comprehensive evaluation of TV series on cross-platform.

  17. Application research of cloud computing in emergency system platform of nuclear accidents

    International Nuclear Information System (INIS)

    Zhang Yan; Yue Huiguo; Lin Quanyi; Yue Feng

    2013-01-01

    This paper described the key technology of the concept of cloud computing, service type and implementation methods. Combined with the upgrade demand of nuclear accident emergency system platform, the paper also proposed the application design of private cloud computing platform, analyzed safety of cloud platform and the characteristics of cloud disaster recovery. (authors)

  18. Research and Development of Target Recognition and Location Crawling Platform based on Binocular Vision

    Science.gov (United States)

    Xu, Weidong; Lei, Zhu; Yuan, Zhang; Gao, Zhenqing

    2018-03-01

    The application of visual recognition technology in industrial robot crawling and placing operation is one of the key tasks in the field of robot research. In order to improve the efficiency and intelligence of the material sorting in the production line, especially to realize the sorting of the scattered items, the robot target recognition and positioning crawling platform based on binocular vision is researched and developed. The images were collected by binocular camera, and the images were pretreated. Harris operator was used to identify the corners of the images. The Canny operator was used to identify the images. Hough-chain code recognition was used to identify the images. The target image in the image, obtain the coordinates of each vertex of the image, calculate the spatial position and posture of the target item, and determine the information needed to capture the movement and transmit it to the robot control crawling operation. Finally, In this paper, we use this method to experiment the wrapping problem in the express sorting process The experimental results show that the platform can effectively solve the problem of sorting of loose parts, so as to achieve the purpose of efficient and intelligent sorting.

  19. A new platform for RFID research in Vietnam

    International Nuclear Information System (INIS)

    Tran, Ai Nhan; Nguyen, Son Dat; Thai Pham, Duc Hoang; Nguyen, Thuat Tran; Dang, Chien Mau; Fribourg-Blanc, Eric

    2010-01-01

    Radio-Frequency IDentification (RFID) is a technology that has been emerging for less than a decade as the primary choice to exchange information between objects and their environment. Most of the challenges arise due to the passive nature of the tags placed on objects. The absence of a local power source implies that power management is critical for efficient work of the data exchange link. This paper presents the platform under development at the Laboratory for Nanotechnology to study these challenges. The primary goal of the platform is to implement the complete chain from design and simulation of tags to antenna measurements and field tests of tags through fabrication of real tags on flexible substrates. This structure allows for fundamental and practical studies of new concepts in sensing and wireless networks based on passive tags. A description of the actual achievements is also included

  20. A systematic review of social networking sites: innovative platforms for health research targeting adolescents and young adults.

    Science.gov (United States)

    Park, Bu Kyung; Calamaro, Christina

    2013-09-01

    To review the evidence to determine if social networking sites (SNS) are effective tools for health research in the adolescent and young adult populations. Systematic review of published research articles focused on use of SNS for youth health research. Seventeen articles were selected that met the following criteria: used SNS at any stage of study, participants between 13 and 25 years of age, English language, and both international and national studies. Reviewers categorized selected studies based on the way SNS were used. Utilization of SNS for effectively implementing research with adolescents and young adults include (a) recruitment, (b) intervention, and (c) measurement. Four findings about advantages of using SNS apparent in this review are (a) ease of access to youth, (b) cost effectiveness in recruitment, (c) ease of intervention, and (d) reliable screening venue of mental status and high-risk behaviors. Although this literature review showed relatively minimal research to date on the use of SNS for research targeting adolescents and young adults, the impact of using SNS for health research is of considerable importance for researchers as well as participants. With careful focus, SNS can become a valuable platform to access, recruit, and deliver health interventions in a cost-effective manner to youth populations as well as hard-to-reach minority or underserved populations. The evidence demonstrates the usefulness of SNS as innovative platforms for health promotion among adolescents and young adults. © 2013 Sigma Theta Tau International.

  1. Adaptations of Personal Health Record Platform for Medical Research on Chronic Diseases

    Directory of Open Access Journals (Sweden)

    A. Krukowski

    2015-05-01

    Full Text Available The article reports on experiences in e-Health platforms and services for supporting medical research into the causes and relationships among physiological parameters and health problems concerning different chronic diseases. The Personal Health Record (PHR is a way of standardizing electronic management of medical information between patients and their physicians, including medical bodies collaborating in providing integrated medical care services. We describe roles and aims behind electronic health records, follow with applicable legal and standardizations frameworks and relevant European activities, leading to the presentation of common commercial and open-source implementations of such systems, concluding with the indication of specific adaptations enabling a use of stored personal health data for scientific research into causes and evaluation of chronic illnesses. We describe ethical and privacy concerns that are relevant to using and exchanging electronic health information.

  2. Research on University Network Teaching Platform (Blackboard in Teaching Management

    Directory of Open Access Journals (Sweden)

    Gou Zhao Xia

    2016-01-01

    Full Text Available With rapid development of online education; teaching platform based on the network, as a new instructional mode has become a hot topic in online teaching. In this paper, the he teaching situation and existing problems on online was analyzed by comparing the difference between network teaching platform and traditional classroom teaching. Then the strategies of network teaching management and the case, which is focusing on the characteristics of Blackboard with the application of network teaching management was presents.

  3. Moving Virtual Research Environments from high maintenance Stovepipes to Multi-purpose Sustainable Service-oriented Science Platforms

    Science.gov (United States)

    Klump, Jens; Fraser, Ryan; Wyborn, Lesley; Friedrich, Carsten; Squire, Geoffrey; Barker, Michelle; Moloney, Glenn

    2017-04-01

    The researcher of today is likely to be part of a team distributed over multiple sites that will access data from an external repository and then process the data on a public or private cloud or even on a large centralised supercomputer. They are increasingly likely to use a mixture of their own code, third party software and libraries, or even access global community codes. These components will be connected into a Virtual Research Environments (VREs) that will enable members of the research team who are not co-located to actively work together at various scales to share data, models, tools, software, workflows, best practices, infrastructures, etc. Many VRE's are built in isolation: designed to meet a specific research program with components tightly coupled and not capable of being repurposed for other use cases - they are becoming 'stovepipes'. The limited number of users of some VREs also means that the cost of maintenance per researcher can be unacceptably high. The alternative is to develop service-oriented Science Platforms that enable multiple communities to develop specialised solutions for specific research programs. The platforms can offer access to data, software tools and processing infrastructures (cloud, supercomputers) through globally distributed, interconnected modules. In Australia, the Virtual Geophysics Laboratory (VGL) was initially built to enable a specific set of researchers in government agencies access to specific data sets and a limited number of tools, that is now rapidly evolving into a multi-purpose Earth science platform with access to an increased variety of data, a broader range of tools, users from more sectors and a diversity of computational infrastructures. The expansion has been relatively easy, because of the architecture whereby data, tools and compute resources are loosely coupled via interfaces that are built on international standards and accessed as services wherever possible. In recent years, investments in

  4. Identification of platform levels

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik

    2005-01-01

    reduction, ability to launch a wider product portfolio without increasing resources and reduction of complexity within the whole company. To support the multiple product development process, platform based product development has in many companies such as Philips, VW, Ford etc. proven to be a very effective...... product development in one step and therefore the objective of this paper is to identify levels of platform based product development. The structure of this paper is as follows. First the applied terminology for platforms will be briefly explained and then characteristics between single and multi product...... development will be examined. Based on the identification of the above characteristics five platform levels are described. The research presented in this paper is a result of MSc, Ph.D projects at the Technical University of Denmark and consultancy projects within the organisation of Institute of Product...

  5. Advancing Translational Space Research Through Biospecimen Sharing: Amplified Impact of Studies Utilizing Analogue Space Platforms

    Science.gov (United States)

    Staten, B.; Moyer, E.; Vizir, V.; Gompf, H.; Hoban-Higgins, T.; Lewis, L.; Ronca, A.; Fuller, C. A.

    2016-01-01

    Biospecimen Sharing Programs (BSPs) have been organized by NASA Ames Research Center since the 1960s with the goal of maximizing utilization and scientific return from rare, complex and costly spaceflight experiments. BSPs involve acquiring otherwise unused biological specimens from primary space research experiments for distribution to secondary experiments. Here we describe a collaboration leveraging Ames expertise in biospecimen sharing to magnify the scientific impact of research informing astronaut health funded by the NASA Human Research Program (HRP) Human Health Countermeasures (HHC) Element. The concept expands biospecimen sharing to one-off ground-based studies utilizing analogue space platforms (e.g., Hindlimb Unloading (HLU), Artificial Gravity) for rodent experiments, thereby significantly broadening the range of research opportunities with translational relevance for protecting human health in space and on Earth.

  6. Launching platforms for user-generated content

    OpenAIRE

    Batista, Guilherme Luís Caroço

    2015-01-01

    Field lab: Entrepreneurial and innovative ventures This paper intends to discuss and absorb the Best Practices employed by successful User- Generated Content (UGC)1 platforms and constitute a guide on how to launch a platform without having a cyclical lack of content and users. Research shows that companies have resorted to integration with mature UGC platforms, and providing content by themselves, in an initial state. I conclude that integration possibilities should be explore...

  7. Research on acceleration method of reactor physics based on FPGA platforms

    International Nuclear Information System (INIS)

    Li, C.; Yu, G.; Wang, K.

    2013-01-01

    The physical designs of the new concept reactors which have complex structure, various materials and neutronic energy spectrum, have greatly improved the requirements to the calculation methods and the corresponding computing hardware. Along with the widely used parallel algorithm, heterogeneous platforms architecture has been introduced into numerical computations in reactor physics. Because of the natural parallel characteristics, the CPU-FPGA architecture is often used to accelerate numerical computation. This paper studies the application and features of this kind of heterogeneous platforms used in numerical calculation of reactor physics through practical examples. After the designed neutron diffusion module based on CPU-FPGA architecture achieves a 11.2 speed up factor, it is proved to be feasible to apply this kind of heterogeneous platform into reactor physics. (authors)

  8. The European Photovoltaic Technology Platform

    International Nuclear Information System (INIS)

    Nowak, S.; Aulich, H.; Bal, J.L.; Dimmler, B.; Garnier, A.; Jongerden, G.; Luther, J.; Luque, A.; Milner, A.; Nelson, D.; Pataki, I.; Pearsall, N.; Perezagua, E.; Pietruszko, S.; Rehak, J.; Schellekens, E.; Shanker, A.; Silvestrini, G.; Sinke, W.; Willemsen, H.

    2006-05-01

    The European Photovoltaic Technology Platform is one of the European Technology Platforms, a new instrument proposed by the European Commission. European Technology Platforms (ETPs) are a mechanism to bring together all interested stakeholders to develop a long-term vision to address a specific challenge, create a coherent, dynamic strategy to achieve that vision and steer the implementation of an action plan to deliver agreed programmes of activities and optimise the benefits for all parties. The European Photovoltaic Technology Platform has recently been established to define, support and accompany the implementation of a coherent and comprehensive strategic plan for photovoltaics. The platform will mobilise all stakeholders sharing a long-term European vision for PV, helping to ensure that Europe maintains and improves its industrial position. The platform will realise a European Strategic Research Agenda for PV for the next decade(s). Guided by a Steering Committee of 20 high level decision-makers representing all relevant European PV Stakeholders, the European PV Technology Platform comprises 4 Working Groups dealing with the subjects policy and instruments; market deployment; science, technology and applications as well as developing countries and is supported by a secretariat

  9. AURORA BOREALIS: a polar-dedicated European Research Platform

    Science.gov (United States)

    Wolff-Boenisch, Bonnie; Egerton, Paul; Thiede, Joern; Roberto, Azzolini; Lembke-Jene, Lester

    2010-05-01

    Polar research and in particular the properties of northern and southern high latitude oceans are currently a subject of intense scientific debate and investigations, because they are subject to rapid and dramatic climatic variations. Polar regions react more rapidly and intensively to global change than other regions of the earth. A shrinking of the Arctic sea-ice cover, potentially leading to an opening of sea passages to the north of North America and Eurasia, on the long to a "blue" Arctic Ocean would additionally have a strong impact on transport, commerce and tourism bearing potential risk for humans and complex ecosystems in the future. In spite of their critical role processes and feedbacks, especially in winter but not exclusively, are virtually unknown: The Arctic Ocean for example, it is the only basin of the world's oceans that has essentially not been sampled by the drill ships of the Deep-Sea Drilling Project (DSDP) or the Ocean Drilling Program (ODP) and its long-term environmental history and tectonic structure is therefore poorly known. Exceptions are the ODP Leg 151 and the more recent very successful ACEX-expedition of the Integrated Ocean Drilling Program (IODP) in 2004. To help to address the most pressing questions regarding climate change and related processes, a Pan-European initiative in the field of Earth system science has been put in place: AURORA BOREALIS is the largest environmental research infrastructure on the ESFRI roadmap of the European Community. AURORA BOREALIS is a very powerful research icebreaker, which will enable year-round operations in the Arctic and the Antarctic as well as in the adjacent ocean basins. Equipped with its drilling rig, the vessel is also capable to explore the presently completely unknown Arctic deep-sea floor. Last but not least, the ship is a floating observatory and mobile monitoring platform that permits to measure on a long-term basis comprehensive time series in all research fields relevant to

  10. An FPGA Scalable Software Defined Radio Platform Design for Educational and Research Purposes

    Directory of Open Access Journals (Sweden)

    Marcos Hervás

    2016-06-01

    Full Text Available In a digital modem design, the integration of the Analog to Digital Converters (ADC and Digital to Analog Converters (DAC with the core processor is usually a major issue for the designer. In this paper an FPGA scalable Software Defined Radio platform based on a Spartan-6 as a control unit is presented, developed for both educational and research purposes, which can fit the different application requirements in terms of analog front-end performance, processing unit and cost. The resolution and sampling frequency of the analog front-end are its main adjustable parameters. The processing core requirements involve the FPGA and the communication ports. A multidisciplinary working group was required to design a high performance system for both analog front-end and digital processing core in terms of signal integrity and electromagnetic compatibility. The platform has 5 different peripheral ports ranging from 16 kbps to 2.5 Gbps. The communication ports allow our students to develop a high range of applications for both on-site and online courses applying teaching methodology based on learning by doing using a real system to help them to reach other transversal skills.

  11. PROBA-V Mission Exploitation Platform

    Directory of Open Access Journals (Sweden)

    Erwin Goor

    2016-07-01

    Full Text Available As an extension of the PROBA-Vegetation (PROBA-V user segment, the European Space Agency (ESA, de Vlaamse Instelling voor Technologisch Onderzoek (VITO, and partners TRASYS and Spacebel developed an operational Mission Exploitation Platform (MEP to drastically improve the exploitation of the PROBA-V Earth Observation (EO data archive, the archive from the historical SPOT-VEGETATION mission, and derived products by researchers, service providers, and thematic users. The analysis of the time series of data (petabyte range is addressed, as well as the large scale on-demand processing of the complete archive, including near real-time data. The platform consists of a private cloud environment, a Hadoop-based processing environment and a data manager. Several applications are released to the users, e.g., a full resolution viewing service, a time series viewer, pre-defined on-demand processing chains, and virtual machines with powerful tools and access to the data. After an initial release in January 2016 a research platform was deployed gradually, allowing users to design, debug, and test applications on the platform. From the PROBA-V MEP, access to, e.g., Sentinel-2 and Sentinel-3 data will be addressed as well.

  12. Disentangling Competition Among Platform Driven Strategic Groups

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    2018-01-01

    for the mobile payment market in the United Kingdom as our empirical setting. By conceptualizing digital platforms as layered modular architectures and embracing the theoretical lens of strategic groups, this study supplements prior research by deriving a taxonomy of platform profiles that is grounded...... delivery architecture. The preceding attributes of value creation architecture and value delivery architecture aided us in identifying six profiles associated with mobile payment platforms, which in turn led us to advance three competitive strategies that could be pursued by digital platforms in network...

  13. Development of a Modular Robotic Platform

    Directory of Open Access Journals (Sweden)

    Claudiu Ioan Cirebea

    2014-12-01

    Full Text Available In this paper a modular robotic platform is presented, for students and researchers laboratory work based on the Matlab-Simulink and dSpace real time control platform. The goal of this combination is to stimulate and to experiment with real time hardware and software in courses where mobile robotics is adopted as a motivating platform to introduce mechatronics competencies. Its many possibilities for modifications and extensions make experiments very easy. We used, for example, an omnidirectional mobile robot configuration with three Swedish wheels, whose kinematic model was simulated using Simulink. For real-time control, of the robot, the developed model has been implemented using DSpace platform DS1103.

  14. The Creative Platform

    DEFF Research Database (Denmark)

    Byrge, Christian; Hansen, Søren

    whether you consider thirdgrade teaching, human-resource development, or radical new thinking in product development in a company. The Creative Platform was developed at Aalborg University through a series of research-and-development activities in collaboration with educational institutions and private...

  15. Development of a Historical Hydrological online research and application platform for Switzerland - Historical Hydrological Atlas of Switzerland (HHAS)

    Science.gov (United States)

    Wetter, Oliver

    2017-04-01

    It is planned to develop and maintain a historical hydrological online platform for Switzerland, which shall be specially designed for the needs of research and federal, cantonal or private institutions being interested in hydrological risk assessment and protection measures. The aim is on the one hand to facilitate the access to raw data which generally is needed for further historical hydrological reconstruction and quantification, so that future research will be achieved in significantly shorter time. On the other hand, new historical hydrological research results shall be continuously included in order to establish this platform as a useful tool for the assessment of hydrological risk by including the long term experience of reconstructed pre-instrumental hydrological extreme events like floods and droughts. Meteorological parameters that may trigger extreme hydrological events, like monthly or seasonally resolved reconstructions of temperature and precipitation shall be made accessible in this platform as well. The ultimate goal will be to homogenise the reconstructed hydrological extreme events which usually appeared in the pre anthropogenic influence period under different climatological as well as different hydrological regimes and topographical conditions with the present day state. Long term changes of reconstructed small- to extreme flood seasonality, based on municipal accounting records, will be included in the platform as well. This helps - in combination with the before mentioned meteorological parameters - to provide an increased understanding of the major changes in the generally complex overall system that finally causes hydrological extreme events. The goal of my presentation at the Historical Climatology session is to give an overview about the applied historical climatological and historical hydrological methodologies that are applied on the historical raw data (evidence) to reconstruct pre instrumental hydrological events and meteorological

  16. Research progress of anti-icing/deicing technologies for polar ships and offshore platforms

    Directory of Open Access Journals (Sweden)

    XIE Qiang

    2017-01-01

    Full Text Available The polar regions present adverse circumstances of high humidity and strong air-sea exchange. As such, the surfaces of ships and platforms (oil exploiting and drilling platforms serving in polar regions can easily be frozen by ice accretion, which not only affects the operation of the equipment but also threatens safety. This paper summarizes the status of the anti-icing/deicing technologies of both China and abroad for polar ships and offshore platforms, and introduces the various effects of ice accretion on polar ships and offshore platforms, and the resulting safety impacts. It then reviews existing anti-icing/deicing technologies and methods of both China and abroad, including such active deicing methods as electric heating, infrared heating and ultrasonic guided wave deicing, as well as such passive deicing methods as super hydrophobic coating, sacrificial coating, aqueous lubricating layer coating and low cross-link density (with interfacial slippage coating, summarizes their applicability to polar ships and offshore platforms, and finally discusses their advantages/disadvantages.

  17. How scientific visions matter: insights from three long-term socio-ecological research (LTSER) platforms under construction in Europe

    NARCIS (Netherlands)

    Mauz, I.; Peltola, T.; Granjou, C.; Bommel, van S.; Buijs, A.E.

    2012-01-01

    Long-Term Socio-Ecological Research (LTSER) has been introduced to change the current approach to ecology and turn it into a big science. LTSER Platforms are currently being created across Europe. They are expected to enhance ecology's capacity to produce useful knowledge for facing global

  18. Contrasting platform thinking and product modularization

    DEFF Research Database (Denmark)

    Boer, Henrike Engele Elisabeth; Persson, Magnus

    2015-01-01

    Product modularization and platform thinking are both practices that seek to alleviate the negative impact of product customization and variety on internal operations by relying on economies of substitution. Through the use of a standardized pool of components and interfaces, these practices aim...... to create a broad spectrum of product choices. At first sight, product modularization and platform thinking are very similar. The difference between these practices can, however, be found in the manner in which they employ standardization. Where product modularization focuses on creating standardized...... variants. There is a general lack of research addressing the contingency factors that dictate the appropriateness of the use of product modularization and platform thinking in different contexts. To our knowledge, no large-scale empirical research has been reported in which the two concepts, contextual...

  19. Do mature innovation platforms make a difference in agricultural research for development? a meta-analysis of case studies

    NARCIS (Netherlands)

    Schut, Marc; Cadilhon, Jean-Joseph; Misiko, Michael; Dror, Iddo

    2018-01-01

    Innovation Platforms (IPs) have become a popular vehicle in agricultural research for development (AR4D). The IP promise is that integrating scientific and local knowledge results in innovations that can have impact at scale. Many studies have uncovered how IPs work in various countries, value

  20. tranSMART: An Open Source and Community-Driven Informatics and Data Sharing Platform for Clinical and Translational Research.

    Science.gov (United States)

    Athey, Brian D; Braxenthaler, Michael; Haas, Magali; Guo, Yike

    2013-01-01

    tranSMART is an emerging global open source public private partnership community developing a comprehensive informatics-based analysis and data-sharing cloud platform for clinical and translational research. The tranSMART consortium includes pharmaceutical and other companies, not-for-profits, academic entities, patient advocacy groups, and government stakeholders. The tranSMART value proposition relies on the concept that the global community of users, developers, and stakeholders are the best source of innovation for applications and for useful data. Continued development and use of the tranSMART platform will create a means to enable "pre-competitive" data sharing broadly, saving money and, potentially accelerating research translation to cures. Significant transformative effects of tranSMART includes 1) allowing for all its user community to benefit from experts globally, 2) capturing the best of innovation in analytic tools, 3) a growing 'big data' resource, 4) convergent standards, and 5) new informatics-enabled translational science in the pharma, academic, and not-for-profit sectors.

  1. Design and Research of Service Platform for Protection and Dissemination of Cultural Heritage Resources of The Silk Road in the Territory of China

    Science.gov (United States)

    Zhang, L.; Zhang, W.; Zeng, S. J.; Na, W.; Yang, H.; Huang, J.; Tan, X. D.; Sun, Z. J.

    2015-08-01

    The Silk Road, a major traffic route across the Eurasia continent, has been a convergence for the exchange, communication and dissemination of various cultures such as nations, materials, religions and arts for more than two thousand years. And the cultural heritage along the long and complicate route has been also attractive. In recent years, the Silk Road - the Road Network along the Chang'an-Tianshan Mountain has been listed in the Directory of World Cultural Heritage. The rare and rich cultural resources along the Silk Road, especially those in the territory of China, have attracted attentions of the world. This article describes the research ideas, methods, processes and results of the planning design on the internet-based dissemination services platform system for cultural heritage resources. First of all, it has defined the targeting for dissemination services and the research methods applied for the Silk Road heritage resources, based on scientific and objective spatial measurement and research on history and geography, to carry on the excavation of values of cultural resource for the target users. Then, with the front-end art exhibit by means of innovative IT, time and space maps of cultural heritage resources, interactive graphics display, panoramic three-dimensional virtual tour, and the Silk Road topics as the main features, a comprehensive and multi-angle cultural resources dissemination services platform is built. The research core of the platform is a demand-oriented system design on the basis of cultural resources and features as the fundamental, the value of contemporary manifestation as the foundation, and cultural dissemination and service as a starting point. This platform has achieved, temporal context generalization, interest profiles extension, online and offline adaptation, and other prominent innovations. On the basis of routes heritage resource protection and dissemination services with complex relationship between time and space, and the

  2. Demand forecasting and information platform in tourism

    Directory of Open Access Journals (Sweden)

    Li Yue

    2017-05-01

    Full Text Available Information asymmetry and the bullwhip effect have been serious problems in the tourism supply chain. Based on platform theory, this paper established a mathematical model to explore the inner mechanism of a platform’s influence on stakeholders’ ability to forecast demand in tourism. Results showed that the variance of stakeholders’ demand predictions with a platform was smaller than the variance without a platform, which meant that a platform would improve predictions of demand for stakeholders. The higher information-processing ability of the platform also had other effects on demand forecasting. Research on the inner logic of the platform’s influence on stakeholders has important theoretical and realistic value. This area is worthy of further study.

  3. Collaborative and cognitive network platforms : Vision and research challenges

    NARCIS (Netherlands)

    Onur, E.; Durmus, Y.; Hawas, M.G.; Heemstra de Groot, S.M.; Niemegeers, I.G.M.M.

    2011-01-01

    In this paper, we present a visionary concept referred to as Collaborative and Cognitive Network Platforms (CCNPs) as a future-proof solution for creating a dependable, self-organizing and self-managing communication substrate for effective ICT solutions to societal problems. CCNP creates a

  4. E-Sourcing platforms as reasonable marketing tools for suppliers

    OpenAIRE

    Göbl, Martin; Greiter, Thomas

    2014-01-01

    Research questions: E-sourcing platforms offer purchasing organisations often easy access to a high number of relevant suppliers, their goods and services and the accord-ing prices. For the suppliers, e-sourcing platforms are a good and easy pos-sibility to present their products and services to the relevant buyers and to get in contact with potential customers. Subject of this research will be the question, whether e-sourcing platforms are also a reasonable marketing tool for suppliers in or...

  5. The National Cohort of Dairy Farms--a data collection platform for mastitis research in Canada.

    Science.gov (United States)

    Reyher, K K; Dufour, S; Barkema, H W; Des Côteaux, L; Devries, T J; Dohoo, I R; Keefe, G P; Roy, J-P; Scholl, D T

    2011-03-01

    Costs and feasibility of extensive sample collection and processing are major obstacles to mastitis epidemiology research. Studies are often consequentially limited, and fundamental mastitis researchers rarely have the opportunity to conduct their work in epidemiologically valid populations. To mitigate these limitations, the Canadian Bovine Mastitis Research Network has optimized research funds by creating a data collection platform to provide epidemiologically meaningful data for several simultaneous research endeavors. This platform consists of a National Cohort of Dairy Farms (NCDF), Mastitis Laboratory Network, and Mastitis Pathogen Culture Collection. This paper describes the implementation and operation of the NCDF, explains its sampling protocols and data collection, and documents characteristics, strengths and limitations of these data for current and potential users. The NCDF comprises 91 commercial dairy farms in 6 provinces sampled over a 2-yr period. Primarily Holstein-Friesian herds participating in Dairy Herd Improvement milk recording were selected in order to achieve a uniform distribution among 3 strata of bulk tank somatic cell counts and to reflect regional proportions of freestall housing systems. Standardized protocols were implemented for repeated milk samplings on clinical mastitis cases, fresh and randomly selected lactating cows, and cows at dry-off and after calving. Just fewer than 133,000 milk samples were collected. Demographic and production data were recorded at individual cow and farm levels. Health management data are documented and extensive questionnaire data detailing farm management and cleanliness information are also captured. The Laboratory Network represents coordinated regional mastitis bacteriology laboratories using standardized procedures. The Culture Collection archives isolates recovered from intramammary infections of cows in the NCDF and contains over 16,500 isolates, all epidemiologically cross-referenced between

  6. MO-E-18C-05: Global Health Catalyst: A Novel Platform for Enhancing Access to Medical Physics Education and Research Excellence (AMPERE)

    International Nuclear Information System (INIS)

    Ngwa, W; Moreau, M; Asana, L

    2014-01-01

    Purpose: To develop a platform for catalyzing collaborative global Cancer Care Education and Research (CaRE), with a prime focus on enhancing Access to Medical Physics Education and Research Excellence (AMPERE) Methods: An analysis of over 50 global health collaborations between partners in the U.S. and low and middle income countries (LMIC) in Africa was carried out to assess the models of collaborations in Education and Research and relative success. A survey was carried out with questions including: the nature of the collaboration, how it was initiated, impact of culture and other factors, and recommendations for catalyzing/enhancing such collaborations. An online platform called Global Health Catalyst was developed for enhancing AMPERE. Results: The analysis yielded three main models for global health collaborations with survey providing key recommendations on how to enhance such collaborations. Based on this, the platform was developed, and customized to allow Medical Physicists and other Radiation oncology (RadOnc) professionals interested in participating in Global health to readily do so e.g. teach an online course module, participate in training Medical Physicists or other RadOnc health professionals in LMIC, co-mentor students, residents or postdocs, etc. The growing list of features on the platform also include: a feature to enable people to easily find each other, form teams, operate more effectively as partners from different disciplines, institutions, nations and cultural backgrounds, share tools and technologies, obtain seed funding to develop curricula and/or embark upon new areas of investigation, and participate in humanitarian outreach: remote treatment planning assistance, and participation in virtual Chart Rounds, etc. Conclusion: The developed Global Health Catalyst platform could enable any Medical Physicist or RadoOnc professional interested in global health to readily participate in the Education/training of next generation Rad

  7. MO-E-18C-05: Global Health Catalyst: A Novel Platform for Enhancing Access to Medical Physics Education and Research Excellence (AMPERE)

    Energy Technology Data Exchange (ETDEWEB)

    Ngwa, W [Harvard Medical School, Boston, MA (United States); University of Massachusetts, Lowell, Massachusetts (United States); Moreau, M [University of Massachusetts, Lowell, Massachusetts (United States); Asana, L [African Renaissance Ambassador Corp, Orlando, FL (United States)

    2014-06-15

    Purpose: To develop a platform for catalyzing collaborative global Cancer Care Education and Research (CaRE), with a prime focus on enhancing Access to Medical Physics Education and Research Excellence (AMPERE) Methods: An analysis of over 50 global health collaborations between partners in the U.S. and low and middle income countries (LMIC) in Africa was carried out to assess the models of collaborations in Education and Research and relative success. A survey was carried out with questions including: the nature of the collaboration, how it was initiated, impact of culture and other factors, and recommendations for catalyzing/enhancing such collaborations. An online platform called Global Health Catalyst was developed for enhancing AMPERE. Results: The analysis yielded three main models for global health collaborations with survey providing key recommendations on how to enhance such collaborations. Based on this, the platform was developed, and customized to allow Medical Physicists and other Radiation oncology (RadOnc) professionals interested in participating in Global health to readily do so e.g. teach an online course module, participate in training Medical Physicists or other RadOnc health professionals in LMIC, co-mentor students, residents or postdocs, etc. The growing list of features on the platform also include: a feature to enable people to easily find each other, form teams, operate more effectively as partners from different disciplines, institutions, nations and cultural backgrounds, share tools and technologies, obtain seed funding to develop curricula and/or embark upon new areas of investigation, and participate in humanitarian outreach: remote treatment planning assistance, and participation in virtual Chart Rounds, etc. Conclusion: The developed Global Health Catalyst platform could enable any Medical Physicist or RadoOnc professional interested in global health to readily participate in the Education/training of next generation Rad

  8. Unraveling Platform Strategies: A Review from an Organizational Ambidexterity Perspective

    Directory of Open Access Journals (Sweden)

    Xing Wan

    2017-05-01

    Full Text Available Platform strategies, which highlight the interdependence in and evolution of business ecosystems, are increasingly relevant for sustainable business models in the digital era. So far, platform research has existed as a fragmented body of insights from different fields, but an integrated theoretical perspective can lead to a more coherent understanding of the research overall. Organizational ambidexterity emphasizes the balance between exploration and exploitation, which is particularly conducive to understanding the sustainability of a firm. Using an organizational ambidexterity perspective, the authors analyze five platform strategies: pricing, openness, integration, differentiation, and envelopment. This paper provides a systematic review of the theoretical and empirical studies in leading management, economics, and information systems journals from 2000 to 2016. The findings show that platform strategies can help platform owners achieve ambidexterity by domain, temporal, and organizational separation. Finally, this paper proposes an agenda for future research.

  9. CyberTORCS: An Intelligent Vehicles Simulation Platform for Cooperative Driving

    Directory of Open Access Journals (Sweden)

    Ming Yang

    2011-05-01

    Full Text Available Simulation platforms play an important role in helping intelligent vehicle research, especially for the research of cooperative driving due to the high cost and risk of the real experiments. In order to ease and bring more convenience for cooperative driving tests, we introduce an intelligent vehicle simulation platform, called CyberTORCS, for the research in cooperative driving. Details of the simulator modules including vehicle body control, vehicle visualization modeling and track visualization modeling are presented. Two simulation examples are given to validate the feasibility and effectiveness of the proposed simulation platform.

  10. Space Science Cloud: a Virtual Space Science Research Platform Based on Cloud Model

    Science.gov (United States)

    Hu, Xiaoyan; Tong, Jizhou; Zou, Ziming

    Through independent and co-operational science missions, Strategic Pioneer Program (SPP) on Space Science, the new initiative of space science program in China which was approved by CAS and implemented by National Space Science Center (NSSC), dedicates to seek new discoveries and new breakthroughs in space science, thus deepen the understanding of universe and planet earth. In the framework of this program, in order to support the operations of space science missions and satisfy the demand of related research activities for e-Science, NSSC is developing a virtual space science research platform based on cloud model, namely the Space Science Cloud (SSC). In order to support mission demonstration, SSC integrates interactive satellite orbit design tool, satellite structure and payloads layout design tool, payload observation coverage analysis tool, etc., to help scientists analyze and verify space science mission designs. Another important function of SSC is supporting the mission operations, which runs through the space satellite data pipelines. Mission operators can acquire and process observation data, then distribute the data products to other systems or issue the data and archives with the services of SSC. In addition, SSC provides useful data, tools and models for space researchers. Several databases in the field of space science are integrated and an efficient retrieve system is developing. Common tools for data visualization, deep processing (e.g., smoothing and filtering tools), analysis (e.g., FFT analysis tool and minimum variance analysis tool) and mining (e.g., proton event correlation analysis tool) are also integrated to help the researchers to better utilize the data. The space weather models on SSC include magnetic storm forecast model, multi-station middle and upper atmospheric climate model, solar energetic particle propagation model and so on. All the services above-mentioned are based on the e-Science infrastructures of CAS e.g. cloud storage and

  11. Evaluation of Variable Refrigerant Flow Systems Performance on Oak Ridge National Laboratory s Flexible Research Platform: Part 3 Simulation Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Im, Piljae [ORNL; Cho, Heejin [Mississippi State University (MSU); Kim, Dongsu [Mississippi State University (MSU); Cox, Sam [Mississippi State University (MSU)

    2016-08-01

    This report provides second-year project simulation results for the multi-year project titled “Evaluation of Variable Refrigeration Flow (VRF) system on Oak Ridge National Laboratory (ORNL)’s Flexible Research Platform (FRP).”

  12. Design and research on the platform of network manufacture product electronic trading

    Science.gov (United States)

    Zhou, Zude; Liu, Quan; Jiang, Xuemei

    2003-09-01

    With the rapid globalization of market and business, E-trading affects every manufacture enterprise. However, the security of network manufacturing products of transmission on Internet is very important. In this paper we discussed the protocol of fair exchange and platform for network manufacture products E-trading based on fair exchange protocol and digital watermarking techniques. The platform realized reliable and copyright protection.

  13. Experimental platforms for behavioral experiments on social-ecological systems

    Directory of Open Access Journals (Sweden)

    Marco A. Janssen

    2014-12-01

    Full Text Available Recently, there has been an increased interest in using behavioral experiments to study hypotheses on the governance of social-ecological systems. A diversity of software tools are used to implement such experiments. We evaluated various publicly available platforms that could be used in research and education on the governance of social-ecological systems. The aims of the various platforms are distinct, and this is noticeable in the differences in their user-friendliness and their adaptability to novel research questions. The more easily accessible platforms are useful for prototyping experiments and for educational purposes to illustrate theoretical concepts. To advance novel research aims, more elaborate programming experience is required to either implement an experiment from scratch or adjust existing experimental software. There is no ideal platform best suited for all possible use cases, but we have provided a menu of options and their associated trade-offs.

  14. Design for game based learning platforms

    DEFF Research Database (Denmark)

    Sørensen, Birgitte Holm; Meyer, Bente

    2010-01-01

    This paper focuses on the challenges related to the design of game based learning platforms for formal learning contexts that are inspired by the pupil's leisure time related use of web 2.0. The paper is based on the project Serious Games on a Global Market Place (2007-2011) founded by the Danish...... of web 2.0 and integrates theories of learning, didactics, games, play, communication, multimodality and different pedagogical approaches. In relation to the introduced model the teacher role is discussed.......This paper focuses on the challenges related to the design of game based learning platforms for formal learning contexts that are inspired by the pupil's leisure time related use of web 2.0. The paper is based on the project Serious Games on a Global Market Place (2007-2011) founded by the Danish...... Council for Strategic Research, in which an online game-based platform for English as a foreign language in primary school is studied. The paper presents a model for designing for game based learning platforms. This design is based on cultural and ethnographic based research on children's leisure time use...

  15. Radionuclide release calculations for selected severe accident scenarios. PWR, ice condenser design

    Energy Technology Data Exchange (ETDEWEB)

    Denning, R S; Gieseke, J A; Cybulskis, P; Lee, K W; Jordan, H; Curtis, L A; Kelly, R F; Kogan, V; Schumacher, P M

    1986-07-01

    This report presents results of analyses of the environmental releases of fission products (source terms) for severe accident scenarios in a pressurized water reactor with an ice-condenser containment. The analyses were performed to support the Severe Accident Risk Reduction/Risk Rebaselining Program (SARRP) which is being undertaken for the U.S. Nuclear Regulatory Commission by Sandia National Laboratories. In the SARRP program, risk estimates are being generated for a number of reference plant designs. The Sequoyah Plant has been used in this study as an example of a PWR ice-condenser plant. (author)

  16. Radionuclide release calculations for selected severe accident scenarios. Volume 3. PWR, subatmospheric containment design

    International Nuclear Information System (INIS)

    Denning, R.S.; Gieseke, J.A.; Cybulskis, P.; Lee, K.W.; Jordan, H.; Curtis, L.A.; Kelly, R.F.; Kogan, V.; Schumacher, P.M.

    1986-07-01

    This report presents results of analyses of the enviromental releases of fission products (source terms) for severe accident scenarios in a pressurized water reactor with a subatmospheric containment design. The analyses were performed to support the Severe Accident Risk Reduction/Risk Rebaselining Program (SARRP) which is being undertaken for the US Nuclear Regulatory Commission by Sandia National Laboratories. In the SARRP program, risk estimates are being generated for a number of reference plant designs. the Surry plant has been used in this study as the reference plant for a subatmospheric design

  17. Innovative and applied research on big data platforms of smart heritage

    Science.gov (United States)

    Qiu, J.; Li, J.; Sun, H.

    2015-08-01

    Big data has huge commercial value and potential. Under the background of big data, a heritage site is faced with a number of questions and challenges such as, how to accelerate industrial innovation, benign competition and the creation of new business value. Based on the analysis of service data from the national archaeological site and park, Yuan Ming Yuan, this paper investigates the common problems of site management operations such as, inappropriate cultural interpretation, insufficient consumer demand and so on. In order to solve these operational problems, a new service system called the "one platform - three systems" was put forward. This system includes the smart heritage platform and three management systems: the smart heritage management system, the 3-O (Online-Offline-Onsite) service system and the digital explanation system. Combined with the 3-O marketing operation, the platform can realize bidirectional interaction between heritage site management units and tourists, which can also benefit visitors to the heritage site by explaining the culture and history of the heritage site, bring about more demand for cultural information and expand the social and economic benefits.

  18. Design of a Maglev Vibration Test Platform for the Research of Maglev Vehicle-girder Coupled Vibration Problem

    Directory of Open Access Journals (Sweden)

    Zhou Danfeng

    2017-01-01

    Full Text Available The maglev vehicle-girder coupled vibration problem has been encountered in many maglev test or commercial lines, which significantly degrade the performance of the maglev train. In previous research on the principle of the coupled vibration problem, it has been discovered that the fundamental model of the maglev girder can be simplified as a series of mass-spring resonators of different but related resonance frequencies, and that the stability of the vehicle-girder coupled system can be investigated by separately examining the stability of each mass-spring resonator – electromagnet coupled system. Based on this conclusion, a maglev test platform, which includes a single electromagnetic suspension control system, is built for experimental study of the coupled vibration problem. The guideway of the test platform is supported by a number of springs so as to change its flexibility. The mass of the guideway can also be changed by adjusting extra weights attached to it. By changing the flexibility and mass of the guideway, the rules of the maglev vehicle-girder coupled vibration problem are to be examined through experiments, and related theory on the vehicle-girder self-excited vibration proposed in previous research is also testified.

  19. Strategies Used by Professors through Virtual Educational Platforms in Face-to-Face Classes: A View from the Chamilo Platform

    Science.gov (United States)

    Valencia, Heriberto Gonzalez; Villota Enriquez, Jackeline Amparo; Agredo, Patricia Medina

    2017-01-01

    This study consisted in characterizing the strategies used by professors; implemented through virtual educational platforms. The context of this research were the classrooms of the Santiago de Cali University and the virtual space of the Chamilo virtual platform, where two professors from the Faculty of Education of the same university…

  20. SU-E-T-157: CARMEN: A MatLab-Based Research Platform for Monte Carlo Treatment Planning (MCTP) and Customized System for Planning Evaluation

    International Nuclear Information System (INIS)

    Baeza, J.A.; Ureba, A.; Jimenez-Ortega, E.; Barbeiro, A.R.; Plaza, A. Leal; Lagares, J.I.

    2015-01-01

    Purpose: Although there exist several radiotherapy research platforms, such as: CERR, the most widely used and referenced; SlicerRT, which allows treatment plan comparison from various sources; and MMCTP, a full MCTP system; it is still needed a full MCTP toolset that provides users complete control of calculation grids, interpolation methods and filters in order to “fairly” compare results from different TPSs, supporting verification with experimental measurements. Methods: This work presents CARMEN, a MatLab-based platform including multicore and GPGPU accelerated functions for loading RT data; designing treatment plans; and evaluating dose matrices and experimental data.CARMEN supports anatomic and functional imaging in DICOM format, as well as RTSTRUCT, RTPLAN and RTDOSE. Besides, it contains numerous tools to accomplish the MCTP process, managing egs4phant and phase space files.CARMEN planning mode assist in designing IMRT, VMAT and MERT treatments via both inverse and direct optimization. The evaluation mode contains a comprehensive toolset (e.g. 2D/3D gamma evaluation, difference matrices, profiles, DVH, etc.) to compare datasets from commercial TPS, MC simulations (i.e. 3ddose) and radiochromic film in a user-controlled manner. Results: CARMEN has been validated against commercial RTPs and well-established evaluation tools, showing coherent behavior of its multiple algorithms. Furthermore, CARMEN platform has been used to generate competitive complex treatment that has been published in comparative studies. Conclusion: A new research oriented MCTP platform with a customized validation toolset has been presented. Despite of being coded with a high-level programming language, CARMEN is agile due to the use of parallel algorithms. The wide-spread use of MatLab provides straightforward access to CARMEN’s algorithms to most researchers. Similarly, our platform can benefit from the MatLab community scientific developments as filters, registration algorithms

  1. SU-E-T-157: CARMEN: A MatLab-Based Research Platform for Monte Carlo Treatment Planning (MCTP) and Customized System for Planning Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Baeza, J.A.; Ureba, A.; Jimenez-Ortega, E.; Barbeiro, A.R.; Plaza, A. Leal [Universidad de Sevilla, Departamento de Fisiologia Medica y Biofisica, Seville (Spain); Lagares, J.I. [Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas (CIEMAT), Madrid (Spain)

    2015-06-15

    Purpose: Although there exist several radiotherapy research platforms, such as: CERR, the most widely used and referenced; SlicerRT, which allows treatment plan comparison from various sources; and MMCTP, a full MCTP system; it is still needed a full MCTP toolset that provides users complete control of calculation grids, interpolation methods and filters in order to “fairly” compare results from different TPSs, supporting verification with experimental measurements. Methods: This work presents CARMEN, a MatLab-based platform including multicore and GPGPU accelerated functions for loading RT data; designing treatment plans; and evaluating dose matrices and experimental data.CARMEN supports anatomic and functional imaging in DICOM format, as well as RTSTRUCT, RTPLAN and RTDOSE. Besides, it contains numerous tools to accomplish the MCTP process, managing egs4phant and phase space files.CARMEN planning mode assist in designing IMRT, VMAT and MERT treatments via both inverse and direct optimization. The evaluation mode contains a comprehensive toolset (e.g. 2D/3D gamma evaluation, difference matrices, profiles, DVH, etc.) to compare datasets from commercial TPS, MC simulations (i.e. 3ddose) and radiochromic film in a user-controlled manner. Results: CARMEN has been validated against commercial RTPs and well-established evaluation tools, showing coherent behavior of its multiple algorithms. Furthermore, CARMEN platform has been used to generate competitive complex treatment that has been published in comparative studies. Conclusion: A new research oriented MCTP platform with a customized validation toolset has been presented. Despite of being coded with a high-level programming language, CARMEN is agile due to the use of parallel algorithms. The wide-spread use of MatLab provides straightforward access to CARMEN’s algorithms to most researchers. Similarly, our platform can benefit from the MatLab community scientific developments as filters, registration algorithms

  2. CILogon: An Integrated Identity and Access Management Platform for Science

    Science.gov (United States)

    Basney, J.

    2016-12-01

    When scientists work together, they use web sites and other software to share their ideas and data. To ensure the integrity of their work, these systems require the scientists to log in and verify that they are part of the team working on a particular science problem. Too often, the identity and access verification process is a stumbling block for the scientists. Scientific research projects are forced to invest time and effort into developing and supporting Identity and Access Management (IAM) services, distracting them from the core goals of their research collaboration. CILogon provides an IAM platform that enables scientists to work together to meet their IAM needs more effectively so they can allocate more time and effort to their core mission of scientific research. The CILogon platform enables federated identity management and collaborative organization management. Federated identity management enables researchers to use their home organization identities to access cyberinfrastructure, rather than requiring yet another username and password to log on. Collaborative organization management enables research projects to define user groups for authorization to collaboration platforms (e.g., wikis, mailing lists, and domain applications). CILogon's IAM platform serves the unique needs of research collaborations, namely the need to dynamically form collaboration groups across organizations and countries, sharing access to data, instruments, compute clusters, and other resources to enable scientific discovery. CILogon provides a software-as-a-service platform to ease integration with cyberinfrastructure, while making all software components publicly available under open source licenses to enable re-use. Figure 1 illustrates the components and interfaces of this platform. CILogon has been operational since 2010 and has been used by over 7,000 researchers from more than 170 identity providers to access cyberinfrastructure including Globus, LIGO, Open Science Grid

  3. Software platform virtualization in chemistry research and university teaching.

    Science.gov (United States)

    Kind, Tobias; Leamy, Tim; Leary, Julie A; Fiehn, Oliver

    2009-11-16

    Modern chemistry laboratories operate with a wide range of software applications under different operating systems, such as Windows, LINUX or Mac OS X. Instead of installing software on different computers it is possible to install those applications on a single computer using Virtual Machine software. Software platform virtualization allows a single guest operating system to execute multiple other operating systems on the same computer. We apply and discuss the use of virtual machines in chemistry research and teaching laboratories. Virtual machines are commonly used for cheminformatics software development and testing. Benchmarking multiple chemistry software packages we have confirmed that the computational speed penalty for using virtual machines is low and around 5% to 10%. Software virtualization in a teaching environment allows faster deployment and easy use of commercial and open source software in hands-on computer teaching labs. Software virtualization in chemistry, mass spectrometry and cheminformatics is needed for software testing and development of software for different operating systems. In order to obtain maximum performance the virtualization software should be multi-core enabled and allow the use of multiprocessor configurations in the virtual machine environment. Server consolidation, by running multiple tasks and operating systems on a single physical machine, can lead to lower maintenance and hardware costs especially in small research labs. The use of virtual machines can prevent software virus infections and security breaches when used as a sandbox system for internet access and software testing. Complex software setups can be created with virtual machines and are easily deployed later to multiple computers for hands-on teaching classes. We discuss the popularity of bioinformatics compared to cheminformatics as well as the missing cheminformatics education at universities worldwide.

  4. Technical Research on the Electric Power Big Data Platform of Smart Grid

    OpenAIRE

    Ruiguang MA; Haiyan Wang; Quanming Zhang; Yuan Liang

    2017-01-01

    Through elaborating on the associated relationship among electric power big data, cloud computing and smart grid, this paper put forward general framework of electric power big data platform based on the smart grid. The general framework of the platform is divided into five layers, namely data source layer, data integration and storage layer, data processing and scheduling layer, data analysis layer and application layer. This paper makes in-depth exploration and studies the integrated manage...

  5. An Experimental Platform for Autonomous Bus Development

    Directory of Open Access Journals (Sweden)

    Héctor Montes

    2017-11-01

    Full Text Available Nowadays, with highly developed instrumentation, sensing and actuation technologies, it is possible to foresee an important advance in the field of autonomous and/or semi-autonomous transportation systems. Intelligent Transport Systems (ITS have been subjected to very active research for many years, and Bus Rapid Transit (BRT is one area of major interest. Among the most promising transport infrastructures, the articulated bus is an interesting, low cost, high occupancy capacity and friendly option. In this paper, an experimental platform for research on the automatic control of an articulated bus is presented. The aim of the platform is to allow full experimentation in real conditions for testing technological developments and control algorithms. The experimental platform consists of a mobile component (a commercial articulated bus fully instrumented and a ground test area composed of asphalt roads inside the Consejo Superior de Investigaciones Científicas (CSIC premises. This paper focuses also on the development of a human machine interface to ease progress in control system evaluation. Some experimental results are presented in order to show the potential of the proposed platform.

  6. An overview on development and application of an experimental platform for quantitative cardiac imaging research in rabbit models of myocardial infarction.

    Science.gov (United States)

    Feng, Yuanbo; Bogaert, Jan; Oyen, Raymond; Ni, Yicheng

    2014-10-01

    To exploit the advantages of using rabbits for cardiac imaging research and to tackle the technical obstacles, efforts have been made under the framework of a doctoral research program. In this overview article, by cross-referencing the current literature, we summarize how we have developed a preclinical cardiac research platform based on modified models of reperfused myocardial infarction (MI) in rabbits; how the in vivo manifestations of cardiac imaging could be closely matched with those ex vivo macro- and microscopic findings; how these imaging outcomes could be quantitatively analyzed, validated and demonstrated; and how we could apply this cardiac imaging platform to provide possible solutions to certain lingering diagnostic and therapeutic problems in experimental cardiology. In particular, tissue components in acute cardiac ischemia have been stratified and characterized, post-infarct lipomatous metaplasia (LM) as a common but hardly illuminated clinical pathology has been identified in rabbit models, and a necrosis avid tracer as well as an anti-ischemic drug have been successfully assessed for their potential utilities in clinical cardiology. These outcomes may interest the researchers in the related fields and help strengthen translational research in cardiovascular diseases.

  7. Central American and Caribbean Citizen Security Platform | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Collaborative research platform This initiative will establish a real and virtual space known as the Central American and Caribbean Security Platform. It will bring together the region's scholars, practitioners, attorneys, journalists, and other stakeholders into regular, constructive dialogue with specialists dedicated to finding ...

  8. Research of MOOC Platform Based “Internet +”

    OpenAIRE

    Wang Guang Xing; Chen Yan

    2016-01-01

    This paper is devoted to examining the construction of MOOC platform based “Internet +”. It firstly introduced the “Internet+” model, the “Internet + education” influence and the significance of education. Then, it analyzed the existing problems in the development of the current MOOC, and put forward the model of “Internet + MOOC” through the method of software engineering. It explored the advantage of “Internet + MOOC” mode and promoting the function to the education teaching. This paper put...

  9. Microneedle Platforms for Cell Analysis

    KAUST Repository

    Kavaldzhiev, Mincho

    2017-11-01

    -dependent delivery rate has been found. The electromagnetic delivery concept is particularly promising for future in-vivo applications. Finally, the micro-needle platforms developed in this work will provide researchers with new capabilities that will help them to further advance the field of mechanobiology, drug delivery treatments, stem cells research and more. The proposed platforms are capable of applying various stimuli, analyzing cell responses in real time, drug delivery, and they also have the potential to add additional functionalities in the future.

  10. Systems Biology-Based Platforms to Accelerate Research of Emerging Infectious Diseases.

    Science.gov (United States)

    Oh, Soo Jin; Choi, Young Ki; Shin, Ok Sarah

    2018-03-01

    Emerging infectious diseases (EIDs) pose a major threat to public health and security. Given the dynamic nature and significant impact of EIDs, the most effective way to prevent and protect against them is to develop vaccines in advance. Systems biology approaches provide an integrative way to understand the complex immune response to pathogens. They can lead to a greater understanding of EID pathogenesis and facilitate the evaluation of newly developed vaccine-induced immunity in a timely manner. In recent years, advances in high throughput technologies have enabled researchers to successfully apply systems biology methods to analyze immune responses to a variety of pathogens and vaccines. Despite recent advances, computational and biological challenges impede wider application of systems biology approaches. This review highlights recent advances in the fields of systems immunology and vaccinology, and presents ways that systems biology-based platforms can be applied to accelerate a deeper understanding of the molecular mechanisms of immunity against EIDs. © Copyright: Yonsei University College of Medicine 2018.

  11. Technology review: prototyping platforms for monitoring ambient conditions.

    Science.gov (United States)

    Afolaranmi, Samuel Olaiya; Ramis Ferrer, Borja; Martinez Lastra, Jose Luis

    2018-05-08

    The monitoring of ambient conditions in indoor spaces is very essential owing to the amount of time spent indoors. Specifically, the monitoring of air quality is significant because contaminated air affects the health, comfort and productivity of occupants. This research work presents a technology review of prototyping platforms for monitoring ambient conditions in indoor spaces. It involves the research on sensors (for CO 2 , air quality and ambient conditions), IoT platforms, and novel and commercial prototyping platforms. The ultimate objective of this review is to enable the easy identification, selection and utilisation of the technologies best suited for monitoring ambient conditions in indoor spaces. Following the review, it is recommended to use metal oxide sensors, optical sensors and electrochemical sensors for IAQ monitoring (including NDIR sensors for CO 2 monitoring), Raspberry Pi for data processing, ZigBee and Wi-Fi for data communication, and ThingSpeak IoT platform for data storage, analysis and visualisation.

  12. Stratospheric Platforms for Monitoring Purposes

    International Nuclear Information System (INIS)

    Konigorski, D.; Gratzel, U.; Obersteiner, M.; Schneidereit, M.

    2010-01-01

    Stratospheric platforms are emerging systems based on challenging technology. Goal is to create a platform, payload, and mission design which is able to complement satellite services on a local scale. Applications are close to traditional satellite business in telecommunication, navigation, science, and earth observation and include for example mobile telecommunications, navigation augmentation, atmospheric research, or border control. Stratospheric platforms could potentially support monitoring activities related to safeguards, e.g. by imagery of surfaces, operational conditions of nuclear facilities, and search for undeclared nuclear activities. Stratospheric platforms are intended to be flown in an altitude band between 16 and 30 km, above 16-20 km to take advantage of usually lower winds facilitating station keeping, below 30 km to limit the challenges to achieve a reasonable payload at acceptable platform sizes. Stratospheric platforms could substitute satellites which are expensive and lack upgrade capabilities for new equipment. Furthermore they have practically an unlimited time over an area of interest. It is intended to keep the platforms operational and maintenance free on a 24/7 basis with an average deployment time of 3 years. Geostationary satellites lack resolution. Potential customers like Armed Forces, National Agencies and commercial customers have indicated interest in the use of stratospheric platforms. Governmental entities are looking for cheaper alternatives to communications and surveillance satellites and stratospheric platforms could offer the following potential advantages: Lower operational cost than satellite or UAV (Unmanned Aerial Vehicles) constellation (fleet required); Faster deployment than satellite constellation; Repositioning capability and ability to loiter as required; Persistent long-term real-time services over a fairly large regional spot; Surge capability: Able to extend capability (either monitoring or communications

  13. SmartR: an open-source platform for interactive visual analytics for translational research data.

    Science.gov (United States)

    Herzinger, Sascha; Gu, Wei; Satagopam, Venkata; Eifes, Serge; Rege, Kavita; Barbosa-Silva, Adriano; Schneider, Reinhard

    2017-07-15

    In translational research, efficient knowledge exchange between the different fields of expertise is crucial. An open platform that is capable of storing a multitude of data types such as clinical, pre-clinical or OMICS data combined with strong visual analytical capabilities will significantly accelerate the scientific progress by making data more accessible and hypothesis generation easier. The open data warehouse tranSMART is capable of storing a variety of data types and has a growing user community including both academic institutions and pharmaceutical companies. tranSMART, however, currently lacks interactive and dynamic visual analytics and does not permit any post-processing interaction or exploration. For this reason, we developed SmartR , a plugin for tranSMART, that equips the platform not only with several dynamic visual analytical workflows, but also provides its own framework for the addition of new custom workflows. Modern web technologies such as D3.js or AngularJS were used to build a set of standard visualizations that were heavily improved with dynamic elements. The source code is licensed under the Apache 2.0 License and is freely available on GitHub: https://github.com/transmart/SmartR . reinhard.schneider@uni.lu. Supplementary data are available at Bioinformatics online. © The Author(s) 2017. Published by Oxford University Press.

  14. An Investigation of Digital Payment Platform Designs

    DEFF Research Database (Denmark)

    Kazan, Erol; Damsgaard, Jan

    2014-01-01

    This paper focuses on the triumph march of mobile phones that currently are annexing music players, navigation devices, and cameras as separate physical objects. The next target is set on payment. Through synthesizing available literature, we construct a framework for studying digital payment...... platforms that combines platform, technology and business design aspects. The framework is applied to conduct a comparative case study of digital payment platforms. Four types of market actors are considered: banks, mobile network operators, merchants, and startups, which are incumbents and disrupters....... By hosting third-party services, payment instruments are evolving from single-purpose to multi-functional ones. Our research extends existing payment literature from the MSP perspective to emphasize certain digital payment platform components, which impact strategies and complementary products....

  15. Fresh water generators onboard a floating platform

    International Nuclear Information System (INIS)

    Tewari, P.K.; Verma, R.K.; Misra, B.M.; Sadhulkan, H.K.

    1997-01-01

    A dependable supply of fresh water is essential for any ocean going vessel. The operating and maintenance personnel on offshore platforms and marine structures also require a constant and regular supply of fresh water to meet their essential daily needs. A seawater thermal desalination unit onboard delivers good quality fresh water from seawater. The desalination units developed by Bhabha Atomic Research Centre (BARC) suitable for ocean going vessels and offshore platforms have been discussed. Design considerations of such units with reference to floating platforms and corrosive environments have been presented. The feasibility of coupling a low temperature vacuum evaporation (LTVE) desalination plant suitable for an onboard floating platform to a PHWR nuclear power plant has also been discussed. (author). 1 ref., 3 figs, 2 tabs

  16. WindS@UP: The e-Science Platform for WindScanner.eu

    Science.gov (United States)

    Gomes, Filipe; Correia Lopes, João; Laginha Palma, José; Frölén Ribeiro, Luís

    2014-06-01

    The WindScanner e-Science platform architecture and the underlying premises are discussed. It is a collaborative platform that will provide a repository for experimental data and metadata. Additional data processing capabilities will be incorporated thus enabling in-situ data processing. Every resource in the platform is identified by a Uniform Resource Identifier (URI), enabling an unequivocally identification of the field(s) campaign(s) data sets and metadata associated with the data set or experience. This feature will allow the validation of field experiment results and conclusions as all managed resources will be linked. A centralised node (Hub) will aggregate the contributions of 6 to 8 local nodes from EC countries and will manage the access of 3 types of users: data-curator, data provider and researcher. This architecture was designed to ensure consistent and efficient research data access and preservation, and exploitation of new research opportunities provided by having this "Collaborative Data Infrastructure". The prototype platform-WindS@UP-enables the usage of the platform by humans via a Web interface or by machines using an internal API (Application Programming Interface). Future work will improve the vocabulary ("application profile") used to describe the resources managed by the platform.

  17. “Modular Biospheres” New testbed platforms for public environmental education and research

    Science.gov (United States)

    Nelson, M.; Dempster, W. F.; Allen, J. P.

    This paper will review the potential of a relatively new type of testbed platform for environmental education and research because of the unique advantages resulting from their material closure and separation from the outside environment. These facilities which we term "modular biospheres", have emerged from research centered on space life support research but offer a wider range of application. Examples of this type of facility include the Bios-3 facility in Russia, the Japanese CEEF (Closed Ecological Experiment Facility), the NASA Kennedy Space Center Breadboard facility, the Biosphere 2 Test Module and the Laboratory Biosphere. Modular biosphere facilities offer unique research and public real-time science education opportunities. Ecosystem behavior can be studied since initial state conditions can be precisely specified and tracked over different ranges of time. With material closure (apart from very small air exchange rate which can be determined), biogeochemical cycles between soil and soil microorganisms, water, plants, and atmosphere can be studied in detail. Such studies offer a major advance from studies conducted with phytotrons which because of their small size, limit the number of organisms to a very small number, and which crucially do not have a high degree of atmospheric, water and overall material closure. Modular biospheres take advantage of the unique properties of closure, as representing a distinct system "metabolism" and therefore are essentially a "mini-world". Though relatively large in comparison with most phytotrons and ecological microcosms, which are now standard research and educational tools, modular biospheres are small enough that they can be economically reconfigured to reflect a changing research agenda. Some design elements include lighting via electric lights and/or sunlight, hydroponic or soil substrate for plants, opaque or glazed structures, and variable volume chambers or other methods to handle atmospheric pressure

  18. Payment Platform

    DEFF Research Database (Denmark)

    Hjelholt, Morten; Damsgaard, Jan

    2012-01-01

    thoroughly and substitute current payment standards in the decades to come. This paper portrays how digital payment platforms evolve in socio-technical niches and how various technological platforms aim for institutional attention in their attempt to challenge earlier platforms and standards. The paper...... applies a co-evolutionary multilevel perspective to model the interplay and processes between technology and society wherein digital payment platforms potentially will substitute other payment platforms just like the credit card negated the check. On this basis this paper formulate a multilevel conceptual...

  19. Health Care Transformation Through Collaboration on Open-Source Informatics Projects: Integrating a Medical Applications Platform, Research Data Repository, and Patient Summarization

    Science.gov (United States)

    McCoy, Allison B; Wright, Adam; Wattanasin, Nich; Sittig, Dean F; Murphy, Shawn N

    2013-01-01

    Background The Strategic Health IT Advanced Research Projects (SHARP) program seeks to conquer well-understood challenges in medical informatics through breakthrough research. Two SHARP centers have found alignment in their methodological needs: (1) members of the National Center for Cognitive Informatics and Decision-making (NCCD) have developed knowledge bases to support problem-oriented summarizations of patient data, and (2) Substitutable Medical Apps, Reusable Technologies (SMART), which is a platform for reusable medical apps that can run on participating platforms connected to various electronic health records (EHR). Combining the work of these two centers will ensure wide dissemination of new methods for synthesized views of patient data. Informatics for Integrating Biology and the Bedside (i2b2) is an NIH-funded clinical research data repository platform in use at over 100 sites worldwide. By also working with a co-occurring initiative to SMART-enabling i2b2, we can confidently write one app that can be used extremely broadly. Objective Our goal was to facilitate development of intuitive, problem-oriented views of the patient record using NCCD knowledge bases that would run in any EHR. To do this, we developed a collaboration between the two SHARPs and an NIH center, i2b2. Methods First, we implemented collaborative tools to connect researchers at three institutions. Next, we developed a patient summarization app using the SMART platform and a previously validated NCCD problem-medication linkage knowledge base derived from the National Drug File-Reference Terminology (NDF-RT). Finally, to SMART-enable i2b2, we implemented two new Web service “cells” that expose the SMART application programming interface (API), and we made changes to the Web interface of i2b2 to host a “carousel” of SMART apps. Results We deployed our SMART-based, NDF-RT-derived patient summarization app in this SMART-i2b2 container. It displays a problem-oriented view of

  20. Health care transformation through collaboration on open-source informatics projects: integrating a medical applications platform, research data repository, and patient summarization.

    Science.gov (United States)

    Klann, Jeffrey G; McCoy, Allison B; Wright, Adam; Wattanasin, Nich; Sittig, Dean F; Murphy, Shawn N

    2013-05-30

    The Strategic Health IT Advanced Research Projects (SHARP) program seeks to conquer well-understood challenges in medical informatics through breakthrough research. Two SHARP centers have found alignment in their methodological needs: (1) members of the National Center for Cognitive Informatics and Decision-making (NCCD) have developed knowledge bases to support problem-oriented summarizations of patient data, and (2) Substitutable Medical Apps, Reusable Technologies (SMART), which is a platform for reusable medical apps that can run on participating platforms connected to various electronic health records (EHR). Combining the work of these two centers will ensure wide dissemination of new methods for synthesized views of patient data. Informatics for Integrating Biology and the Bedside (i2b2) is an NIH-funded clinical research data repository platform in use at over 100 sites worldwide. By also working with a co-occurring initiative to SMART-enabling i2b2, we can confidently write one app that can be used extremely broadly. Our goal was to facilitate development of intuitive, problem-oriented views of the patient record using NCCD knowledge bases that would run in any EHR. To do this, we developed a collaboration between the two SHARPs and an NIH center, i2b2. First, we implemented collaborative tools to connect researchers at three institutions. Next, we developed a patient summarization app using the SMART platform and a previously validated NCCD problem-medication linkage knowledge base derived from the National Drug File-Reference Terminology (NDF-RT). Finally, to SMART-enable i2b2, we implemented two new Web service "cells" that expose the SMART application programming interface (API), and we made changes to the Web interface of i2b2 to host a "carousel" of SMART apps. We deployed our SMART-based, NDF-RT-derived patient summarization app in this SMART-i2b2 container. It displays a problem-oriented view of medications and presents a line-graph display of

  1. Impact of product platforms on lean production systems : evidence from industrial machinery manufacturing

    NARCIS (Netherlands)

    Alblas, A.A.; Wortmann, J.C.

    2012-01-01

    The present study describes the effects of product platform changes on lean production systems. Current research into product platforms focuses mostly on the development stage. However, although the initial development of platforms is an important issue, product platforms often evolve during later

  2. NEON's Mobile Deployment Platform: A research tool for integrating ecological processes across scales

    Science.gov (United States)

    Sanclements, M.

    2016-12-01

    Here we provide an update on construction of the five NEON Mobile Deployment Platforms (MDPs) as well as a description of the infrastructure and sensors available to researchers in the near future. Additionally, we include information (i.e. timelines and procedures) on requesting MDPs for PI led projects. The MDPs will provide the means to observe stochastic or spatially important events, gradients, or quantities that cannot be reliably observed using fixed location sampling (e.g. fires and floods). Due to the transient temporal and spatial nature of such events, the MDPs are designed to accommodate rapid deployment for time periods up to 1 year. Broadly, the MDPs are comprised of infrastructure and instrumentation capable of functioning individually or in conjunction with one another to support observations of ecological change, as well as education, training and outreach. More specifically, the MDPs include the capability to make tower based measures of ecosystem exchange, radiation, and precipitation in conjunction with baseline soils data such as CO2 flux, and soil temperature and moisture. An aquatics module is also available with the MDP to facilitate research integrating terrestrial and aquatic processes. Ultimately, the NEON MDPs provides a tool for linking PI led research to the continental scale data sets collected by NEON.

  3. Intelligent tools for building a scientific information platform from research to implementation

    CERN Document Server

    Skonieczny, Łukasz; Rybiński, Henryk; Kryszkiewicz, Marzena; Niezgódka, Marek

    2014-01-01

    This book is a selection of results obtained within three years of research performed under SYNAT—a nation-wide scientific project aiming at creating an infrastructure for scientific content storage and sharing for academia, education and open knowledge society in Poland. The book is intended to be the last of the series related to the SYNAT project. The previous books, titled “Intelligent Tools for Building a Scientific Information Platform” and “Intelligent Tools for Building a Scientific Information Platform: Advanced Architectures and Solutions”, were published as volumes 390 and 467 in Springer's Studies in Computational Intelligence. Its contents is based on the SYNAT 2013 Workshop held in Warsaw. The papers included in this volume present an overview and insight into information retrieval, repository systems, text processing, ontology-based systems, text mining, multimedia data processing and advanced software engineering, addressing the problems of implementing intelligent tools for building...

  4. YARP: Yet Another Robot Platform

    Directory of Open Access Journals (Sweden)

    Lorenzo Natale

    2008-11-01

    Full Text Available We describe YARP, Yet Another Robot Platform, an open-source project that encapsulates lessons from our experience in building humanoid robots. The goal of YARP is to minimize the effort devoted to infrastructure-level software development by facilitating code reuse, modularity and so maximize research-level development and collaboration. Humanoid robotics is a "bleeding edge" field of research, with constant flux in sensors, actuators, and processors. Code reuse and maintenance is therefore a significant challenge. We describe the main problems we faced and the solutions we adopted. In short, the main features of YARP include support for inter-process communication, image processing as well as a class hierarchy to ease code reuse across different hardware platforms. YARP is currently used and tested on Windows, Linux and QNX6 which are common operating systems used in robotics.

  5. Service platforms management strategy: case study of an interior design firm

    Directory of Open Access Journals (Sweden)

    Leonel Del Rey de Melo Filho

    2015-03-01

    Full Text Available Platform management is a strategic tool for firms of various sizes, although it demands studies in the service sector. The aim of this paper is to investigate a use of platform management, designed to reach flexibility and operational dynamics in service projects. The studied platform is evaluated as a strategic resource in a particular case. The contributions of the service platform were explored from Resource-Based View (RBV and Service Marketing (SM perspectives, to study their effects on firms’ performance. The research strategy used was an exploratory case study in an interior design firm. The data collection techniques included a participant observation, document analysis and a focus group with firm managers. The research demonstrated that platform management is a strategic resource that assists with the planning of internal capabilities, market positioning, and provides better customer service.

  6. Research on Hydrodynamic Interference Suppression of Bottom-Mounted Monitoring Platform with Fairing Structure

    Science.gov (United States)

    Wang, Zhen; Zheng, Yi; Mao, Yu-feng; Wang, Ya-zhou; Yu, Yan-ting; Liu, Hong-ning

    2018-03-01

    In the disturbance of unsteady flow field under the sea, the monitoring accuracy and precision of the bottom-mounted acoustic monitoring platform will decrease. In order to reduce the hydrodynamic interference, the platform wrapped with fairing structure and separated from the retrieval unit is described. The suppression effect evaluation based on the correlation theory of sound pressure and particle velocity for spherical wave in infinite homogeneous medium is proposed and the difference value between them is used to evaluate the hydrodynamic restraining performance of the bottom-mounted platform under far field condition. Through the sea test, it is indicated that the platform with sparse layers fairing structure (there are two layers for the fairing, in which the inside layer is 6-layers sparse metal net, and the outside layer is 1-layer polyester cloth, and then it takes sparse layers for short) has no attenuation in the sound pressure response to the sound source signal, but obvious suppression in the velocity response to the hydrodynamic noise. The effective frequency of the fairing structure is decreased below 10 Hz, and the noise magnitude is reduced by 10 dB. With the comparison of different fairing structures, it is concluded that the tighter fairing structure can enhance the performance of sound transmission and flow restraining.

  7. CER Hub: An informatics platform for conducting comparative effectiveness research using multi-institutional, heterogeneous, electronic clinical data.

    Science.gov (United States)

    Hazlehurst, Brian L; Kurtz, Stephen E; Masica, Andrew; Stevens, Victor J; McBurnie, Mary Ann; Puro, Jon E; Vijayadeva, Vinutha; Au, David H; Brannon, Elissa D; Sittig, Dean F

    2015-10-01

    Comparative effectiveness research (CER) requires the capture and analysis of data from disparate sources, often from a variety of institutions with diverse electronic health record (EHR) implementations. In this paper we describe the CER Hub, a web-based informatics platform for developing and conducting research studies that combine comprehensive electronic clinical data from multiple health care organizations. The CER Hub platform implements a data processing pipeline that employs informatics standards for data representation and web-based tools for developing study-specific data processing applications, providing standardized access to the patient-centric electronic health record (EHR) across organizations. The CER Hub is being used to conduct two CER studies utilizing data from six geographically distributed and demographically diverse health systems. These foundational studies address the effectiveness of medications for controlling asthma and the effectiveness of smoking cessation services delivered in primary care. The CER Hub includes four key capabilities: the ability to process and analyze both free-text and coded clinical data in the EHR; a data processing environment supported by distributed data and study governance processes; a clinical data-interchange format for facilitating standardized extraction of clinical data from EHRs; and a library of shareable clinical data processing applications. CER requires coordinated and scalable methods for extracting, aggregating, and analyzing complex, multi-institutional clinical data. By offering a range of informatics tools integrated into a framework for conducting studies using EHR data, the CER Hub provides a solution to the challenges of multi-institutional research using electronic medical record data. Copyright © 2015. Published by Elsevier Ireland Ltd.

  8. WindS@UP: The e-Science Platform for WindScanner.eu

    International Nuclear Information System (INIS)

    Gomes, Filipe; Palma, José Laginha; Lopes, João Correia; Ribeiro, Luís Frölén

    2014-01-01

    The WindScanner e-Science platform architecture and the underlying premises are discussed. It is a collaborative platform that will provide a repository for experimental data and metadata. Additional data processing capabilities will be incorporated thus enabling in-situ data processing. Every resource in the platform is identified by a Uniform Resource Identifier (URI), enabling an unequivocally identification of the field(s) campaign(s) data sets and metadata associated with the data set or experience. This feature will allow the validation of field experiment results and conclusions as all managed resources will be linked. A centralised node (Hub) will aggregate the contributions of 6 to 8 local nodes from EC countries and will manage the access of 3 types of users: data-curator, data provider and researcher. This architecture was designed to ensure consistent and efficient research data access and preservation, and exploitation of new research opportunities provided by having this C ollaborative Data Infrastructure . The prototype platform-WindS@UP-enables the usage of the platform by humans via a Web interface or by machines using an internal API (Application Programming Interface). Future work will improve the vocabulary ( a pplication profile ) used to describe the resources managed by the platform

  9. Biochem-Env, a platform of environmental biochemistry for research in ecology and ecotoxicology

    OpenAIRE

    Grondin, Virginie; Nelieu, Sylvie; Crouzet, Olivier; Hedde, Mickaël; Mougin, Christian

    2016-01-01

    The consortium AnaEE-France (http://www.anaee-s.fr) aims at understanding and predicting the biodiversity and ecosystems dynamics in a context of global change. It will allow improving the understanding of biotic processes/environment interactions, mobilizing experimental and modelling platforms devoted to the biology of continental ecosystems, both terrestrial and aquatic. In this context, the objectives of the platform Biochem-Env (http://www.biochemenv.fr) are to provide skills and innovat...

  10. SU-F-T-59: The Effect of Radiotherapy Dose On Immunoadjuvants

    International Nuclear Information System (INIS)

    Moreau, M; Yasmin-Karim, S; Hao, Y; Ngwa, W

    2016-01-01

    Purpose: Combining radiotherapy with immunotherapy is a promising approach to enhance treatment outcomes for cancer patients. This in-vitro study investigated which radiotherapy doses could adversely affect the function of anti-CD40 mAb, which is one of the key immunoadjuvants under investigations for priming such combination therapy. Methods: Human monocyte derived THP-1 cells were treated with 100ng/mL of PMA in chamber slides to differentiate into macrophage. The THP-1 differentiated macrophages were treated with 2uL/ml of the anti-CD40 mAb and incubated at 37°C and 5% CO2 for 24 hours. Anti-CD40 mAb treated cells were then irradiated at different doses of x-rays: (0, 2, 4, 6, 8, and 12) Gy using the Small Animal Radiotherapy Research Platform (SARRP). After radiation, the cells were left at 4°C for 2 hours followed by immunofluorescence assay. A Nikon inverted live-cell imaging system with fluorescence microscope was used to image the cells mounted on a slide fixed with Dapi. For comparison, an ELISA assay was performed with the antibody added to 3mL of PBS in multiple 10mm dishes. The 10mm dishes were irradiated at different x-ray dose: (0, 2, 4, 6, 8. 10, 12, and 15) Gy using the SARRP. Results: The anti-CD40 mAb activating the macrophages starts to lose their viability due to radiation dose between 8Gy to 12Gy as indicated by the immunofluorescence assay. The ELISA assay, also indicated that such high doses could lead to loss of the mAb’s viability. Conclusion: This work suggests that high doses like those employed during Stereotactic Ablative Radiotherapy may affect the viability of immunoadjuvants such as anti-CD 40. This study avails in-vivo experiments combining radiotherapy with anti-cd40 to get synergistic outcomes, including in the treatment of metastatic disease.

  11. SU-F-T-59: The Effect of Radiotherapy Dose On Immunoadjuvants

    Energy Technology Data Exchange (ETDEWEB)

    Moreau, M [Dana Farber Cancer Institute, Boston, MA (United States); Yasmin-Karim, S [Dana-Farber Cancer Institute, Boston, Massachusetts (United States); Hao, Y [University of Massachusetts Lowell, Lowell, MA (United States); Ngwa, W [Harvard Medical School, Boston, MA (United States)

    2016-06-15

    Purpose: Combining radiotherapy with immunotherapy is a promising approach to enhance treatment outcomes for cancer patients. This in-vitro study investigated which radiotherapy doses could adversely affect the function of anti-CD40 mAb, which is one of the key immunoadjuvants under investigations for priming such combination therapy. Methods: Human monocyte derived THP-1 cells were treated with 100ng/mL of PMA in chamber slides to differentiate into macrophage. The THP-1 differentiated macrophages were treated with 2uL/ml of the anti-CD40 mAb and incubated at 37°C and 5% CO2 for 24 hours. Anti-CD40 mAb treated cells were then irradiated at different doses of x-rays: (0, 2, 4, 6, 8, and 12) Gy using the Small Animal Radiotherapy Research Platform (SARRP). After radiation, the cells were left at 4°C for 2 hours followed by immunofluorescence assay. A Nikon inverted live-cell imaging system with fluorescence microscope was used to image the cells mounted on a slide fixed with Dapi. For comparison, an ELISA assay was performed with the antibody added to 3mL of PBS in multiple 10mm dishes. The 10mm dishes were irradiated at different x-ray dose: (0, 2, 4, 6, 8. 10, 12, and 15) Gy using the SARRP. Results: The anti-CD40 mAb activating the macrophages starts to lose their viability due to radiation dose between 8Gy to 12Gy as indicated by the immunofluorescence assay. The ELISA assay, also indicated that such high doses could lead to loss of the mAb’s viability. Conclusion: This work suggests that high doses like those employed during Stereotactic Ablative Radiotherapy may affect the viability of immunoadjuvants such as anti-CD 40. This study avails in-vivo experiments combining radiotherapy with anti-cd40 to get synergistic outcomes, including in the treatment of metastatic disease.

  12. Model Infrastruktur dan Manajemen Platform Server Berbasis Cloud Computing

    Directory of Open Access Journals (Sweden)

    Mulki Indana Zulfa

    2017-11-01

    Full Text Available Cloud computing is a new technology that is still very rapidly growing. This technology makes the Internet as the main media for the management of data and applications remotely. Cloud computing allows users to run an application without having to think about infrastructure and its platforms. Other technical aspects such as memory, storage, backup and restore, can be done very easily. This research is intended to modeling the infrastructure and management of computer platform in computer network of Faculty of Engineering, University of Jenderal Soedirman. The first stage in this research is literature study, by finding out the implementation model in previous research. Then the result will be combined with a new approach to existing resources and try to implement directly on the existing server network. The results showed that the implementation of cloud computing technology is able to replace the existing platform network.

  13. Influence of the crude oil type to platforming effects

    International Nuclear Information System (INIS)

    Kafedzhiski, Branko; Crvenkova, Suzana; Zikovski, Toni

    1999-01-01

    Platforming is one of the most subtleties processing in refinery industry and it is permanent source for research and finding out the higher optimum degree. Optimum of the last effects of platforming directly depends on many parameters. One of the more important parameters is the type of the crude. The purpose of this work is presenting positive and negative effect to the platforming parameters caused by different types of crude in OCTA Crude Oil Refinery - Skopje (Macedonia). (Author)

  14. Study on concept of web-based reactor piping design data platform

    International Nuclear Information System (INIS)

    Wang Yu; Zhou Yu; Dong Jianling; Meng Yang

    2005-01-01

    For solving the piping design problems such as design data deficiency, designer communication inconvenience and design project inconsistence, Reactor Piping Design Database Platform, which is the main part of the Integrated Nuclear Project Research Platform, is proposed by analyzing the nuclear piping designs in detail. The functions and system structures of the platform are described in the paper for the sake of the realization of the Reactor Piping Design Database Platform. The platform is constituted by web-based management interface, AutoPlant selected as CAD software, and relation database management system (DBMS). (authors)

  15. Platform thinking for services: the case of human resources

    NARCIS (Netherlands)

    Hofman, Erwin; Meijerink, Jeroen Gerard

    2015-01-01

    This paper tests the utility of platform thinking, a design principle that has so far been applied to product development yet under-researched in service settings, for improving the value of services. A key principle of platform thinking is to balance the reuse of service components with the

  16. Cost (non)-recovery by platform technology facilities in the Bio21 Cluster.

    Science.gov (United States)

    Gibbs, Gerard; Clark, Stella; Quinn, Julieanne; Gleeson, Mary Joy

    2010-04-01

    Platform technologies (PT) are techniques or tools that enable a range of scientific investigations and are critical to today's advanced technology research environment. Once installed, they require specialized staff for their operations, who in turn, provide expertise to researchers in designing appropriate experiments. Through this pipeline, research outputs are raised to the benefit of the researcher and the host institution. Platform facilities provide access to instrumentation and expertise for a wide range of users beyond the host institution, including other academic and industry users. To maximize the return on these substantial public investments, this wider access needs to be supported. The question of support and the mechanisms through which this occurs need to be established based on a greater understanding of how PT facilities operate. This investigation was aimed at understanding if and how platform facilities across the Bio21 Cluster meet operating costs. Our investigation found: 74% of platforms surveyed do not recover 100% of direct operating costs and are heavily subsidized by their home institution, which has a vested interest in maintaining the technology platform; platform managers play a major role in establishing the costs and pricing of the facility, normally in a collaborative process with a management committee or institutional accountant; and most facilities have a three-tier pricing structure recognizing internal academic, external academic, and commercial clients.

  17. The Platformization of the Web: Making Web Data Platform Ready

    NARCIS (Netherlands)

    Helmond, A.

    2015-01-01

    In this article, I inquire into Facebook’s development as a platform by situating it within the transformation of social network sites into social media platforms. I explore this shift with a historical perspective on, what I refer to as, platformization, or the rise of the platform as the dominant

  18. CERN Neutrino Platform Hardware

    CERN Document Server

    Nelson, Kevin

    2017-01-01

    My summer research was broadly in CERN's neutrino platform hardware efforts. This project had two main components: detector assembly and data analysis work for ICARUS. Specifically, I worked on assembly for the ProtoDUNE project and monitored the safety of ICARUS as it was transported to Fermilab by analyzing the accelerometer data from its move.

  19. Towards A Framework of Digital Payment Platform Design

    DEFF Research Database (Denmark)

    Kazan, Erol; Damsgaard, Jan

    This paper focuses on the triumph march of mobile phones that currently are annexing music players, navigation devices, and cameras as separate physical objects. The next target is set on payment. Through synthesizing available literature, we construct a framework for studying digital payment...... platforms that combines platform, technology and business design aspects. The framework is applied to conduct a comparative case study of digital payment platforms. Four types of market actors are considered: banks, mobile network operators, merchants, and startups, which are incumbents and disrupters....... By hosting third-party services, payment instruments are evolving from single-purpose to multi-functional ones. Our research extends existing payment literature from the MSP perspective to emphasize certain digital payment platform components, which impact strategies and complementary products....

  20. The research of a gyro-stabilized platform and POS application technology in airborne remote sensing

    Science.gov (United States)

    Xu, Jiang; Du, Qi

    2009-07-01

    The distortion of the collected images usually takes place since the attitude changes along with the flying aerocraft on airborne remote sensing. In order to get original images without distortion, it is necessary to use professional gyro-stabilized platform. In addition to this, another solution of correcting the original image distortion is to utilize later geometric rectification using position & orientation system ( POS ) data. The third way is to utilize medium-accuracy stabilized platform to control the distortion at a tolerant range, and then make use of the data obtained by high-solution posture measure system to correct the low-quality remote sensing images. The third way which takes advantage of both techniques is better than using only one of the two other ways. This paper introduces several kinds of structural forms of gyro-stabilized platforms, and POS acquiring instruments respectively. Then, the essay will make some analysis of their advantages and disadvantages, key technologies and the application experiment of the third method. After the analysis, the thesis discusses the design of the gyro-stabilized platform. The thesis provides crucial information not only for the application technology of gyro-stabilized platform and POS but also for future development.

  1. Temperature profile from NOAA Ship RESEARCHER and other platforms as part of the ARP (Global Atmospheric Research Program) Atlantic Tropical Experiment from 1974-08-28 to 1974-09-20 (NODC Accession 7800314)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using BT and XBT from NOAA Ship RESEARCHER and other platforms in the TOGA area - Atlantic from 28 August 1974 to 20...

  2. Updating the Micro-Tom TILLING platform.

    Science.gov (United States)

    Okabe, Yoshihiro; Ariizumi, Tohru; Ezura, Hiroshi

    2013-03-01

    The dwarf tomato variety Micro-Tom is regarded as a model system for functional genomics studies in tomato. Various tomato genomic tools in the genetic background of Micro-Tom have been established, such as mutant collections, genome information and a metabolomic database. Recent advances in tomato genome sequencing have brought about a significant need for reverse genetics tools that are accessible to the larger community, because a great number of gene sequences have become available from public databases. To meet the requests from the tomato research community, we have developed the Micro-Tom Targeting-Induced Local Lesions IN Genomes (TILLING) platform, which is comprised of more than 5000 EMS-mutagenized lines. The platform serves as a reverse genetics tool for efficiently identifying mutant alleles in parallel with the development of Micro-Tom mutant collections. The combination of Micro-Tom mutant libraries and the TILLING approach enables researchers to accelerate the isolation of desirable mutants for unraveling gene function or breeding. To upgrade the genomic tool of Micro-Tom, the development of a new mutagenized population is underway. In this paper, the current status of the Micro-Tom TILLING platform and its future prospects are described.

  3. MycoCAP - Mycobacterium Comparative Analysis Platform.

    Science.gov (United States)

    Choo, Siew Woh; Ang, Mia Yang; Dutta, Avirup; Tan, Shi Yang; Siow, Cheuk Chuen; Heydari, Hamed; Mutha, Naresh V R; Wee, Wei Yee; Wong, Guat Jah

    2015-12-15

    Mycobacterium spp. are renowned for being the causative agent of diseases like leprosy, Buruli ulcer and tuberculosis in human beings. With more and more mycobacterial genomes being sequenced, any knowledge generated from comparative genomic analysis would provide better insights into the biology, evolution, phylogeny and pathogenicity of this genus, thus helping in better management of diseases caused by Mycobacterium spp.With this motivation, we constructed MycoCAP, a new comparative analysis platform dedicated to the important genus Mycobacterium. This platform currently provides information of 2108 genome sequences of at least 55 Mycobacterium spp. A number of intuitive web-based tools have been integrated in MycoCAP particularly for comparative analysis including the PGC tool for comparison between two genomes, PathoProT for comparing the virulence genes among the Mycobacterium strains and the SuperClassification tool for the phylogenic classification of the Mycobacterium strains and a specialized classification system for strains of Mycobacterium abscessus. We hope the broad range of functions and easy-to-use tools provided in MycoCAP makes it an invaluable analysis platform to speed up the research discovery on mycobacteria for researchers. Database URL: http://mycobacterium.um.edu.my.

  4. Upgrade of The Cyber R and D Platform

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Chang Seong; Lee, Kyung Jong; Yang, Tae Chun; Kim, Tae Sung; Hong, Hyun Joo [Kyungsung Univ., Seoul (Korea, Republic of)

    2007-02-15

    Recently, it is necessary to demonstrate the program and experience the safety of radiation disposal by themselves. The objective of this research is to develop a cyber-based performance assessment program for the radiation disposal which is fit for Korean environment. This research covers the following four areas: - Development of Java-based MDPSA pre-processor - Linking MDPSA code to pre and post-processor. - Linking MDPSA code to Cyber R and D platform - Modification of the Cyber R and D platform. The results of this research can be used as a PR database for the central and local government. Using the web-based system, any person or interest group can plug in the system and experience the safety and clarity of the atomic energy and radiation disposal. Also, within the KAERI, research-related knowledge can be stored as a structured format. This enables the sharing, reusability, transparency, reliability and transferability of research results, and promotes the efficiency of research efforts within and outside of research team.

  5. Upgrade of The Cyber R and D Platform

    International Nuclear Information System (INIS)

    Ko, Chang Seong; Lee, Kyung Jong; Yang, Tae Chun; Kim, Tae Sung; Hong, Hyun Joo

    2007-02-01

    Recently, it is necessary to demonstrate the program and experience the safety of radiation disposal by themselves. The objective of this research is to develop a cyber-based performance assessment program for the radiation disposal which is fit for Korean environment. This research covers the following four areas: - Development of Java-based MDPSA pre-processor - Linking MDPSA code to pre and post-processor. - Linking MDPSA code to Cyber R and D platform - Modification of the Cyber R and D platform. The results of this research can be used as a PR database for the central and local government. Using the web-based system, any person or interest group can plug in the system and experience the safety and clarity of the atomic energy and radiation disposal. Also, within the KAERI, research-related knowledge can be stored as a structured format. This enables the sharing, reusability, transparency, reliability and transferability of research results, and promotes the efficiency of research efforts within and outside of research team

  6. Platform for systems medicine research and diagnostic applications in psychotic disorders-The METSY project

    DEFF Research Database (Denmark)

    Frank, Elisabeth; Maier, Dieter; Pajula, Juha

    2018-01-01

    with detailed metabolic characterisation and multi-variate network analysis is essential in order to identify how lipid dysregulation may contribute to psychotic disorders. A decision support system, integrating clinical, neuropsychological and neuroimaging data, was also developed in order to aid clinical......Psychotic disorders are associated with metabolic abnormalities including alterations in glucose and lipid metabolism. A major challenge in the treatment of psychosis is to identify patients with vulnerable metabolic profiles who may be at risk of developing cardiometabolic co...... these endocannabinoid abnormalities relate to metabolic changes in psychosis. Here we review recent research in the field of metabolic co-morbidities in psychotic disorders as well as the methods to study them and potential links to the endocannabinoid system. We also describe the bioinformatics platforms developed...

  7. Cross-Platform Learning: On the Nature of Children's Learning from Multiple Media Platforms

    Science.gov (United States)

    Fisch, Shalom M.

    2013-01-01

    It is increasingly common for an educational media project to span several media platforms (e.g., TV, Web, hands-on materials), assuming that the benefits of learning from multiple media extend beyond those gained from one medium alone. Yet research typically has investigated learning from a single medium in isolation. This paper reviews several…

  8. Virtual interconnection platform initiative scoping study

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yong [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Kou, Gefei [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Pan, Zuohong [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Liu, Yilu [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); King Jr., Thomas J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-01-01

    Due to security and liability concerns, the research community has limited access to realistic large-scale power grid models to test and validate new operation and control methodologies. It is also difficult for industry to evaluate the relative value of competing new tools without a common platform for comparison. This report proposes to develop a large-scale virtual power grid model that retains basic features and represents future trends of major U.S. electric interconnections. This model will include realistic power flow and dynamics information as well as a relevant geospatial distribution of assets. This model will be made widely available to the research community for various power system stability and control studies and can be used as a common platform for comparing the efficacies of various new technologies.

  9. University technology platform of anticipatory learning

    Directory of Open Access Journals (Sweden)

    Leonid Davidovich Gitelman

    2016-03-01

    Full Text Available The innovative development sets large-scale and challenging tasks, which need to be addressed in the lack-of-knowledge conditions and require the coordination and integration of numerous expert structures, which are scattered around the world and have different status and competencies. One of the mechanisms of integrating the partners’ intellectual and financial resources is provided by the technology platforms. The article discusses the nature and functions of technology platforms and analyzes the experience of their application in different countries with a special emphasis on universities. The article gives an overview of the various interpretations of technology platform concepts. It also describes the development and implementation of the technological platform at the Ural Federal University (research and education centre ‘ENGEC’, which was targeted at organizing anticipatory learning in the sphere of energy engineering and high-tech industries; its mechanism and role in improving different university activities and processes are shown. This platform is based on the original methodology ‘Integrated System of Consulting, Training, and Transformation’ (ISCT, which includes authentic methods and technologies, which are used in the educational process. A significant advantage of this methodology is that it can be applied in university education as well as in corporate training integrated with innovative activities.

  10. Power in the loop real time simulation platform for renewable energy generation

    Science.gov (United States)

    Li, Yang; Shi, Wenhui; Zhang, Xing; He, Guoqing

    2018-02-01

    Nowadays, a large scale of renewable energy sources has been connecting to power system and the real time simulation platform is widely used to carry out research on integration control algorithm, power system stability etc. Compared to traditional pure digital simulation and hardware in the loop simulation, power in the loop simulation has higher accuracy and degree of reliability. In this paper, a power in the loop analog digital hybrid simulation platform has been built and it can be used not only for the single generation unit connecting to grid, but also for multiple new energy generation units connecting to grid. A wind generator inertia control experiment was carried out on the platform. The structure of the inertia control platform was researched and the results verify that the platform is up to need for renewable power in the loop real time simulation.

  11. Topology-oblivious optimization of MPI broadcast algorithms on extreme-scale platforms

    KAUST Repository

    Hasanov, Khalid

    2015-11-01

    © 2015 Elsevier B.V. All rights reserved. Significant research has been conducted in collective communication operations, in particular in MPI broadcast, on distributed memory platforms. Most of the research efforts aim to optimize the collective operations for particular architectures by taking into account either their topology or platform parameters. In this work we propose a simple but general approach to optimization of the legacy MPI broadcast algorithms, which are widely used in MPICH and Open MPI. The proposed optimization technique is designed to address the challenge of extreme scale of future HPC platforms. It is based on hierarchical transformation of the traditionally flat logical arrangement of communicating processors. Theoretical analysis and experimental results on IBM BlueGene/P and a cluster of the Grid\\'5000 platform are presented.

  12. The Melbourne East Monash General Practice Database (MAGNET: Using data from computerised medical records to create a platform for primary care and health services research

    Directory of Open Access Journals (Sweden)

    Danielle Mazza

    2016-07-01

    Full Text Available The Melbourne East MonAsh GeNeral PracticE DaTabase (MAGNET research platform was launched in 2013 to provide a unique data source for primary care and health services research in Australia.  MAGNET contains information from the computerised records of 50 participating general practices and includes data from the computerised medical records of more than 1,100,000 patients.  The data extracted is patient-level episodic information and includes a variety of fields related to patient demographics and historical clinical information, along with the characteristics of the participating general practices.  While there are limitations to the data that is currently available, the MAGNET research platform continues to investigate other avenues for improving the breadth and quality of data, with the aim of providing a more comprehensive picture of primary care in Australia

  13. The Melbourne East Monash General Practice Database (MAGNET): Using data from computerised medical records to create a platform for primary care and health services research.

    Science.gov (United States)

    Mazza, Danielle; Pearce, Christopher; Turner, Lyle Robert; De Leon-Santiago, Maria; McLeod, Adam; Ferriggi, Jason; Shearer, Marianne

    2016-07-04

    The Melbourne East MonAsh GeNeral PracticE DaTabase (MAGNET) research platform was launched in 2013 to provide a unique data source for primary care and health services research in Australia.  MAGNET contains information from the computerised records of 50 participating general practices and includes data from the computerised medical records of more than 1,100,000 patients.  The data extracted is patient-level episodic information and includes a variety of fields related to patient demographics and historical clinical information, along with the characteristics of the participating general practices.  While there are limitations to the data that is currently available, the MAGNET research platform continues to investigate other avenues for improving the breadth and quality of data, with the aim of providing a more comprehensive picture of primary care in Australia.

  14. Comparison of gene coverage of mouse oligonucleotide microarray platforms

    Directory of Open Access Journals (Sweden)

    Medrano Juan F

    2006-03-01

    Full Text Available Abstract Background The increasing use of DNA microarrays for genetical genomics studies generates a need for platforms with complete coverage of the genome. We have compared the effective gene coverage in the mouse genome of different commercial and noncommercial oligonucleotide microarray platforms by performing an in-house gene annotation of probes. We only used information about probes that is available from vendors and followed a process that any researcher may take to find the gene targeted by a given probe. In order to make consistent comparisons between platforms, probes in each microarray were annotated with an Entrez Gene id and the chromosomal position for each gene was obtained from the UCSC Genome Browser Database. Gene coverage was estimated as the percentage of Entrez Genes with a unique position in the UCSC Genome database that is tested by a given microarray platform. Results A MySQL relational database was created to store the mapping information for 25,416 mouse genes and for the probes in five microarray platforms (gene coverage level in parenthesis: Affymetrix430 2.0 (75.6%, ABI Genome Survey (81.24%, Agilent (79.33%, Codelink (78.09%, Sentrix (90.47%; and four array-ready oligosets: Sigma (47.95%, Operon v.3 (69.89%, Operon v.4 (84.03%, and MEEBO (84.03%. The differences in coverage between platforms were highly conserved across chromosomes. Differences in the number of redundant and unspecific probes were also found among arrays. The database can be queried to compare specific genomic regions using a web interface. The software used to create, update and query the database is freely available as a toolbox named ArrayGene. Conclusion The software developed here allows researchers to create updated custom databases by using public or proprietary information on genes for any organisms. ArrayGene allows easy comparisons of gene coverage between microarray platforms for any region of the genome. The comparison presented here

  15. Creating a Knowledge Translation Platform: nine lessons from the Zambia Forum for Health Research

    Directory of Open Access Journals (Sweden)

    Kasonde Joseph M

    2012-10-01

    Full Text Available Abstract The concept of the Knowledge Translation Platform (KTP provides cohesion and leadership for national–level knowledge translation efforts. In this review, we discuss nine key lessons documenting the experience of the Zambia Forum for Health Research, primarily to inform and exchange experience with the growing community of African KTPs. Lessons from ZAMFOHR’s organizational development include the necessity of selecting a multi-stakeholder and -sectoral Board of Directors; performing comprehensive situation analyses to understand not only the prevailing research-and-policy dynamics but a precise operational niche; and selecting a leader that bridges the worlds of research and policy. Programmatic lessons include focusing on building the capacity of both policy-makers and researchers; building a database of local evidence and national-level actors involved in research and policy; and catalyzing work in particular issue areas by identifying leaders from the research community, creating policy-maker demand for research evidence, and fostering the next generation by mentoring both up-and-coming researchers and policy–makers. Ultimately, ZAMFOHR’s experience shows that an African KTP must pay significant attention to its organizational details. A KTP must also invest in the skill base of the wider community and, more importantly, of its own staff. Given the very real deficit of research-support skills in most low-income countries – in synthesis, in communications, in brokering, in training – a KTP must spend significant time and resources in building these types of in-house expertise. And lastly, the role of networking cannot be underestimated. As a fully-networked KTP, ZAMFOHR has benefited from the innovations of other KTPs, from funding opportunities and partnerships, and from invaluable technical support from both African and northern colleagues.

  16. Robot-assisted surgery: an emerging platform for human neuroscience research

    Directory of Open Access Journals (Sweden)

    Anthony Michael Jarc

    2015-06-01

    Full Text Available Classic studies in human sensorimotor control use simplified tasks to uncover fundamental control strategies employed by the nervous system. Such simple tasks are critical for isolating specific features of motor, sensory, or cognitive processes, and for inferring causality between these features and observed behavioral changes. However, it remains unclear how these theories translate to complex sensorimotor tasks or to natural behaviors. Part of the difficulty in performing such experiments has been the lack of appropriate tools for measuring complex motor skills in real-world contexts. Robot-assisted surgery (RAS provides an opportunity to overcome these challenges by enabling unobtrusive measurements of user behavior. In addition, a continuum of tasks with varying complexity – from simple tasks such as those in classic studies to highly complex tasks such as a surgical procedure – can be studied using RAS platforms. Finally, RAS includes a diverse participant population of inexperienced users all the way to expert surgeons. In this perspective, we illustrate how the characteristics of RAS systems make them compelling platforms to extend many theories in human neuroscience, as well as, to develop new theories altogether.

  17. "Where On Mars?": An Open Planetary Mapping Platform for Researchers, Educators, and the General Public

    Science.gov (United States)

    Manaud, Nicolas; Carter, John; Boix, Oriol

    2016-10-01

    The "Where On Mars?" project is essentially the evolution of an existing outreach product developed in collaboration between ESA and CartoDB; an interactive map visualisation of the ESA's ExoMars Rover candidate landing sites (whereonmars.co). Planetary imagery data and maps are increasingly produced by the scientific community, and shared typically as images, in scientific publications, presentations or public outreach websites. However, this media lacks of interactivity and contextual information available for further exploration, making it difficult for any audience to relate one location-based information to another. We believe that interactive web maps are a powerful way of telling stories, engaging with and educating people who, over the last decade, have become familiar with tools such as Google Maps. A few planetary web maps exist but they are either too complex for non-experts, or are closed-systems that do not allows anyone to publish and share content. The long-term vision for the project is to provide researchers, communicators, educators and a worldwide public with an open planetary mapping and social platform enabling them to create, share, communicate and consume research-based content. We aim for this platform to become the reference website everyone will go to learn about Mars and other planets in our Solar System; just like people head to Google Maps to find their bearings or any location-based information. The driver is clearly to create for people an emotional connection with Mars. The short-term objectives for the project are (1) to produce and curate an open repository of basemaps, geospatial data sets, map visualisations, and story maps; (2) to develop a beautifully crafted and engaging interactive map of Mars. Based on user-generated content, the underlying framework should (3) make it easy to create and share additional interactive maps telling specific stories.

  18. Collaborative Development Planning Model of Supporting Product in Platform Innovation Ecosystem

    Directory of Open Access Journals (Sweden)

    Wei Zhang

    2014-01-01

    Full Text Available In order to improve the market value of the product, the platform enterprise often participates in the development process of supporting product of emerging industry’s platform innovation ecosystem. This paper puts forward a revenue sharing contract between the platform company and the supporting company by creating a collaborative development model of the supporting product in the ecosystem, and this paper studies the platform enterprise investment resource property's (complementary or substitution impact on the supporting enterprise R&D efforts and the revenue sharing factor and analyzes collaborative development mechanism of supporting product of emerging industry platform innovation ecosystem. The research indicates that when platform enterprise and supporting enterprise's resources are complementary, the supporting enterprise R&D effort level and revenue sharing coefficient increase as the platform company’s investment increases. When platform enterprise and supporting enterprise's resources are substitutive, the supporting enterprise’s R&D effort level and revenue sharing coefficient decrease as the platform company’s investment increases.

  19. CROPPER: a metagene creator resource for cross-platform and cross-species compendium studies.

    Science.gov (United States)

    Paananen, Jussi; Storvik, Markus; Wong, Garry

    2006-09-22

    Current genomic research methods provide researchers with enormous amounts of data. Combining data from different high-throughput research technologies commonly available in biological databases can lead to novel findings and increase research efficiency. However, combining data from different heterogeneous sources is often a very arduous task. These sources can be different microarray technology platforms, genomic databases, or experiments performed on various species. Our aim was to develop a software program that could facilitate the combining of data from heterogeneous sources, and thus allow researchers to perform genomic cross-platform/cross-species studies and to use existing experimental data for compendium studies. We have developed a web-based software resource, called CROPPER that uses the latest genomic information concerning different data identifiers and orthologous genes from the Ensembl database. CROPPER can be used to combine genomic data from different heterogeneous sources, allowing researchers to perform cross-platform/cross-species compendium studies without the need for complex computational tools or the requirement of setting up one's own in-house database. We also present an example of a simple cross-platform/cross-species compendium study based on publicly available Parkinson's disease data derived from different sources. CROPPER is a user-friendly and freely available web-based software resource that can be successfully used for cross-species/cross-platform compendium studies.

  20. DATABASE REPLICATION IN HETEROGENOUS PLATFORM

    OpenAIRE

    Hendro Nindito; Evaristus Didik Madyatmadja; Albert Verasius Dian Sano

    2014-01-01

    The application of diverse database technologies in enterprises today is increasingly a common practice. To provide high availability and survavibality of real-time information, a database replication technology that has capability to replicate databases under heterogenous platforms is required. The purpose of this research is to find the technology with such capability. In this research, the data source is stored in MSSQL database server running on Windows. The data will be replicated to MyS...

  1. Cross-Platform Technologies

    Directory of Open Access Journals (Sweden)

    Maria Cristina ENACHE

    2017-04-01

    Full Text Available Cross-platform - a concept becoming increasingly used in recent years especially in the development of mobile apps, but this consistently over time and in the development of conventional desktop applications. The notion of cross-platform software (multi-platform or platform-independent refers to a software application that can run on more than one operating system or computing architecture. Thus, a cross-platform application can operate independent of software or hardware platform on which it is execute. As a generic definition presents a wide range of meanings for purposes of this paper we individualize this definition as follows: we will reduce the horizon of meaning and we use functionally following definition: a cross-platform application is a software application that can run on more than one operating system (desktop or mobile identical or in a similar way.

  2. Application of a Smartphone Metabolomics Platform to the Authentication of Schisandra sinensis.

    Science.gov (United States)

    Kwon, Hyuk Nam; Phan, Hong-Duc; Xu, Wen Jun; Ko, Yoon-Joo; Park, Sunghyouk

    2016-05-01

    Herbal medicines have been used for a long time all around the world. Since the quality of herbal preparations depends on the source of herbal materials, there has been a strong need to develop methods to correctly identify the origin of materials. To develop a smartphone metabolomics platform as a simpler and low-cost alternative for the identification of herbal material source. Schisandra sinensis extracts from Korea and China were prepared. The visible spectra of all samples were measured by a smartphone spectrometer platform. This platform included all the necessary measures built-in for the metabolomics research: data acquisition, processing, chemometric analysis and visualisation of the results. The result of the smartphone metabolomics platform was compared to that of NMR-based metabolomics, suggesting the feasibility of smartphone platform in metabolomics research. The smartphone metabolomics platform gave similar results to the NMR method, showing good separation between Korean and Chinese materials and correct predictability for all test samples. With its accuracy and advantages of affordability, user-friendliness, and portability, the smartphone metabolomics platform could be applied to the authentication of other medicinal plants. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  3. Data sharing platforms for de-identified data from human clinical trials.

    Science.gov (United States)

    Huser, Vojtech; Shmueli-Blumberg, Dikla

    2018-04-01

    Data sharing of de-identified individual participant data is being adopted by an increasing number of sponsors of human clinical trials. In addition to standardizing data syntax for shared trial data, semantic integration of various data elements is the focus of several initiatives that define research common data elements. This perspective article, in the first part, compares several data sharing platforms for de-identified clinical research data in terms of their size, policies and supported features. In the second part, we use a case study approach to describe in greater detail one data sharing platform (Data Share from National Institute of Drug Abuse). We present data on the past use of the platform, data formats offered, data de-identification approaches and its use of research common data elements. We conclude with a summary of current and expected future trends that facilitate secondary research use of data from completed human clinical trials.

  4. General Data Acquisition Platform for Wireless Sensor Network Based on CC2538

    Directory of Open Access Journals (Sweden)

    Yang Zhi-Jun

    2017-01-01

    Full Text Available Wireless sensor networks are the hotspots of current research and have very wide application prospects. Its front end is a sensor that can sense and check the external world. This paper takes temperature and humidity as the research object, and builds a wireless sensor network data acquisition platform by combining the Internet of things and the WeChat public platform. The platform uses DHT11 temperature and humidity sensors and CC2538 sensor nodes to obtain the relevant data, through the server and database for data access. The combination with WeChat public platform not only allows us to view the temperature and humidity in the WeChat public, but also allows us to understand the environmental changes of the relevant detection area more conveniently and quickly. The effectiveness of the platform is also demonstrated by the collection of temperature and humidity data.

  5. Balancing platform control and external contribution in third-party development: the boundary resources model

    DEFF Research Database (Denmark)

    Ghazawneh, Ahmad; Henfridsson, Ola

    2013-01-01

    Prior research documents the significance of using platform boundary resources (e.g. application programming interfaces) for cultivating platform ecosystems through third-party development. However, there are few, if any, theoretical accounts of this relationship. To this end, this paper proposes......-party development: self-resourcing, regulation-based securing, diversity resourcing and sovereignty securing. Our research extends and complements existing platform literature and contributes new knowledge about an alternative form of system development...

  6. Influence of the type of crude oil to platforming effects

    International Nuclear Information System (INIS)

    Kafedzhiski, Branko; Crvenkova, Suzana; Zikovski, Toni

    1999-01-01

    Platforming in one of the most subtleties processing in refinery industry and it is permanent source for research and finding out the higher optimum degree. Optimum of the last effects of platforming directly depends on many parameters. One of more important parameters is the type of crude. The purpose of this work is presenting positive and negative effect to the platforming parameters caused by different types of crude in OCTA-Crude Oil Refinery -Skopje, Macedonia. (Original)

  7. CLOUD BASED WEB 3D GIS TAIWAN PLATFORM

    Directory of Open Access Journals (Sweden)

    W.-F. Tsai

    2012-09-01

    Full Text Available This article presents the status of the web 3D GIS platform, which has been developed in the National Applied Research Laboratories. The purpose is to develop a global earth observation 3D GIS platform for applications to disaster monitoring and assessment in Taiwan. For quick response to preliminary and detailed assessment after a natural disaster occurs, the web 3D GIS platform is useful to access, transfer, integrate, display and analyze the multi-scale huge data following the international OGC standard. The framework of cloud service for data warehousing management and efficiency enhancement using VMWare is illustrated in this article.

  8. Reconfigurable, Intelligently-Adaptive, Communication System, an SDR Platform

    Science.gov (United States)

    Roche, Rigoberto J.; Shalkhauser, Mary Jo; Hickey, Joseph P.; Briones, Janette C.

    2016-01-01

    The Space Telecommunications Radio System (STRS) provides a common, consistent framework to abstract the application software from the radio platform hardware. STRS aims to reduce the cost and risk of using complex, configurable and reprogrammable radio systems across NASA missions. The NASA Glenn Research Center (GRC) team made a software defined radio (SDR) platform STRS compliant by adding an STRS operating environment and a field programmable gate array (FPGA) wrapper, capable of implementing each of the platforms interfaces, as well as a test waveform to exercise those interfaces. This effort serves to provide a framework toward waveform development onto an STRS compliant platform to support future space communication systems for advanced exploration missions. The use of validated STRS compliant applications provides tested code with extensive documentation to potentially reduce risk, cost and e ort in development of space-deployable SDRs. This paper discusses the advantages of STRS, the integration of STRS onto a Reconfigurable, Intelligently-Adaptive, Communication System (RIACS) SDR platform, and the test waveform and wrapper development e orts. The paper emphasizes the infusion of the STRS Architecture onto the RIACS platform for potential use in next generation flight system SDRs for advanced exploration missions.

  9. Design of verification platform for wireless vision sensor networks

    Science.gov (United States)

    Ye, Juanjuan; Shang, Fei; Yu, Chuang

    2017-08-01

    At present, the majority of research for wireless vision sensor networks (WVSNs) still remains in the software simulation stage, and the verification platforms of WVSNs that available for use are very few. This situation seriously restricts the transformation from theory research of WVSNs to practical application. Therefore, it is necessary to study the construction of verification platform of WVSNs. This paper combines wireless transceiver module, visual information acquisition module and power acquisition module, designs a high-performance wireless vision sensor node whose core is ARM11 microprocessor and selects AODV as the routing protocol to set up a verification platform called AdvanWorks for WVSNs. Experiments show that the AdvanWorks can successfully achieve functions of image acquisition, coding, wireless transmission, and obtain the effective distance parameters between nodes, which lays a good foundation for the follow-up application of WVSNs.

  10. Continuous Platform Development

    DEFF Research Database (Denmark)

    Nielsen, Ole Fiil

    low risks and investments but also with relatively fuzzy results. When looking for new platform projects, it is important to make sure that the company and market is ready for the introduction of platforms, and to make sure that people from marketing and sales, product development, and downstream......, but continuous product family evolution challenges this strategy. The concept of continuous platform development is based on the fact that platform development should not be a one-time experience but rather an ongoing process of developing new platforms and updating existing ones, so that product family...

  11. Research on website construction based on website group platform of Chengdu sport institution

    Science.gov (United States)

    Hu, Zunyu

    2018-04-01

    This paper describes the necessity of website construction based on the website group of Chengdu sport institute, and discusses the technical features of the website group, Based on the website group platform architecture, the key technologies such as Web Service, AJAX, RSS and other key technologies are used to realize the construction of the website. Based on the website group platform architecture of the site, it effectively solves the information isolated island between the sites, and realizes the information sharing and resource integration. It is also more convenient that site and other sites have composed of site group integrated operation and maintenance.

  12. Colloidal nanophotonics: the emerging technology platform.

    Science.gov (United States)

    Gaponenko, Sergey; Demir, Hilmi Volkan; Seassal, Christian; Woggon, Ulrike

    2016-01-25

    Dating back to decades or even centuries ago, colloidal nanophotonics during the last ten years rapidly extends towards light emitting devices, lasers, sensors and photonic circuitry to manifest itself as an emerging technology platform rather than an entirely academic research field.

  13. KYPO – A Platform for Cyber Defence Exercises

    OpenAIRE

    Čeleda Pavel; Čegan Jakub; Vykopal Jan; Tovarňák Daniel

    2015-01-01

    Correct and timely responses to cyber attacks are crucial for the effective implementation of cyber defence strategies and policies. The number of threats and ingenuity of attackers is ever growing, as is the need for more advanced detection tools, techniques and skilled cyber security professionals. KYPO – Cyber Exercise & Research Platform is focused on modelling and simulating complex computer systems and networks in a virtualized and separated environment. The platform enables realist...

  14. Geospatial Data Management Platform for Urban Groundwater

    Science.gov (United States)

    Gaitanaru, D.; Priceputu, A.; Gogu, C. R.

    2012-04-01

    Due to the large amount of civil work projects and research studies, large quantities of geo-data are produced for the urban environments. These data are usually redundant as well as they are spread in different institutions or private companies. Time consuming operations like data processing and information harmonisation represents the main reason to systematically avoid the re-use of data. The urban groundwater data shows the same complex situation. The underground structures (subway lines, deep foundations, underground parkings, and others), the urban facility networks (sewer systems, water supply networks, heating conduits, etc), the drainage systems, the surface water works and many others modify continuously. As consequence, their influence on groundwater changes systematically. However, these activities provide a large quantity of data, aquifers modelling and then behaviour prediction can be done using monitored quantitative and qualitative parameters. Due to the rapid evolution of technology in the past few years, transferring large amounts of information through internet has now become a feasible solution for sharing geoscience data. Furthermore, standard platform-independent means to do this have been developed (specific mark-up languages like: GML, GeoSciML, WaterML, GWML, CityML). They allow easily large geospatial databases updating and sharing through internet, even between different companies or between research centres that do not necessarily use the same database structures. For Bucharest City (Romania) an integrated platform for groundwater geospatial data management is developed under the framework of a national research project - "Sedimentary media modeling platform for groundwater management in urban areas" (SIMPA) financed by the National Authority for Scientific Research of Romania. The platform architecture is based on three components: a geospatial database, a desktop application (a complex set of hydrogeological and geological analysis

  15. Determination of current loads of floating platform for special purposes

    Science.gov (United States)

    Ma, Guang-ying; Yao, Yun-long; Zhao, Chen-yao

    2017-08-01

    This article studied a new floating offshore platform for special purposes, which was assembled by standard floating modules. The environmental load calculation of the platform is an important part of the research of the ocean platform, which has always been paid attention to by engineers. In addition to wave loads, the wind loads and current loads are also important environmental factors that affect the dynamic response of the offshore platform. The current loads on the bottom structure should not be ignored. By Fluent software, the hydrostatic conditions and external current loads of the platform were calculated in this paper. The coefficient which is independent of the current velocity, namely, current force coefficient, can be fitted through current loads, which can be used for the consequent hydrodynamic and mooring analyses.

  16. The Epilepsy Phenome/Genome Project (EPGP) informatics platform.

    Science.gov (United States)

    Nesbitt, Gerry; McKenna, Kevin; Mays, Vickie; Carpenter, Alan; Miller, Kevin; Williams, Michael

    2013-04-01

    The Epilepsy Phenome/Genome Project (EPGP) is a large-scale, multi-institutional, collaborative network of 27 epilepsy centers throughout the U.S., Australia, and Argentina, with the objective of collecting detailed phenotypic and genetic data on a large number of epilepsy participants. The goals of EPGP are (1) to perform detailed phenotyping on 3750 participants with specific forms of non-acquired epilepsy and 1500 parents without epilepsy, (2) to obtain DNA samples on these individuals, and (3) to ultimately genotype the samples in order to discover novel genes that cause epilepsy. To carry out the project, a reliable and robust informatics platform was needed for standardized electronic data collection and storage, data quality review, and phenotypic analysis involving cases from multiple sites. EPGP developed its own suite of web-based informatics applications for participant tracking, electronic data collection (using electronic case report forms/surveys), data management, phenotypic data review and validation, specimen tracking, electroencephalograph and neuroimaging storage, and issue tracking. We implemented procedures to train and support end-users at each clinical site. Thus far, 3780 study participants have been enrolled and 20,957 web-based study activities have been completed using this informatics platform. Over 95% of respondents to an end-user satisfaction survey felt that the informatics platform was successful almost always or most of the time. The EPGP informatics platform has successfully and effectively allowed study management and efficient and reliable collection of phenotypic data. Our novel informatics platform met the requirements of a large, multicenter research project. The platform has had a high level of end-user acceptance by principal investigators and study coordinators, and can serve as a model for new tools to support future large scale, collaborative research projects collecting extensive phenotypic data. Copyright © 2012

  17. A platform for real-time online health analytics during spaceflight

    Science.gov (United States)

    McGregor, Carolyn

    Monitoring the health and wellbeing of astronauts during spaceflight is an important aspect of any manned mission. To date the monitoring has been based on a sequential set of discontinuous samplings of physiological data to support initial studies on aspects such as weightlessness, and its impact on the cardiovascular system and to perform proactive monitoring for health status. The research performed and the real-time monitoring has been hampered by the lack of a platform to enable a more continuous approach to real-time monitoring. While any spaceflight is monitored heavily by Mission Control, an important requirement within the context of any spaceflight setting and in particular where there are extended periods with a lack of communication with Mission Control, is the ability for the mission to operate in an autonomous manner. This paper presents a platform to enable real-time astronaut monitoring for prognostics and health management within space medicine using online health analytics. The platform is based on extending previous online health analytics research known as the Artemis and Artemis Cloud platforms which have demonstrated their relevance for multi-patient, multi-diagnosis and multi-stream temporal analysis in real-time for clinical management and research within Neonatal Intensive Care. Artemis and Artemis Cloud source data from a range of medical devices capable of transmission of the signal via wired or wireless connectivity and hence are well suited to process real-time data acquired from astronauts. A key benefit of this platform is its ability to monitor their health and wellbeing onboard the mission as well as enabling the astronaut's physiological data, and other clinical data, to be sent to the platform components at Mission Control at each stage when that communication is available. As a result, researchers at Mission Control would be able to simulate, deploy and tailor predictive analytics and diagnostics during the same spaceflight for

  18. Design and Development of Fire Gridding Platform Based on Internet of Things

    Directory of Open Access Journals (Sweden)

    Wei San-Xi

    2016-01-01

    Full Text Available This article describes the construction background about fire gridding platform, reviews the research and progress in fire Internet of Things and fire gridding. The platform includes perception / execution layer, field control layer, network layer, center platform layer and application layer, which provide a good bonding about site control and remote monitoring. This article supplies a detail design for the main functions of application and task flow of fire hazard investigation. At the same time, a digital management platform was developed.

  19. Scoping review and evaluation of SMS/text messaging platforms for mHealth projects or clinical interventions.

    Science.gov (United States)

    Iribarren, Sarah J; Brown, William; Giguere, Rebecca; Stone, Patricia; Schnall, Rebecca; Staggers, Nancy; Carballo-Diéguez, Alex

    2017-05-01

    Mobile technology supporting text messaging interventions (TMIs) continues to evolve, presenting challenges for researchers and healthcare professionals who need to choose software solutions to best meet their program needs. The objective of this review was to systematically identify and compare text messaging platforms and to summarize their advantages and disadvantages as described in peer-reviewed literature. A scoping review was conducted using four steps: 1) identify currently available platforms through online searches and in mHealth repositories; 2) expand evaluation criteria of an mHealth mobile messaging toolkit and integrate prior user experiences as researchers; 3) evaluate each platform's functions and features based on the expanded criteria and a vendor survey; and 4) assess the documentation of platform use in the peer-review literature. Platforms meeting inclusion criteria were assessed independently by three reviewers and discussed until consensus was reached. The PRISMA guidelines were followed to report findings. Of the 1041 potentially relevant search results, 27 platforms met inclusion criteria. Most were excluded because they were not platforms (e.g., guides, toolkits, reports, or SMS gateways). Of the 27 platforms, only 12 were identified in existing mHealth repositories, 10 from Google searches, while five were found in both. The expanded evaluation criteria included 22 items. Results indicate no uniform presentation of platform features and functions, often making these difficult to discern. Fourteen of the platforms were reported as open source, 10 focused on health care and 16 were tailored to meet needs of low resource settings (not mutually exclusive). Fifteen platforms had do-it-yourself setup (programming not required) while the remainder required coding/programming skills or setups could be built to specification by the vendor. Frequently described features included data security and access to the platform via cloud-based systems. Pay

  20. Yeast surface display platform for rapid discovery of conformationally selective nanobodies

    DEFF Research Database (Denmark)

    McMahon, Conor; Baier, Alexander S.; Pascolutti, Roberta

    2018-01-01

    this problem, we report a fully in vitro platform for nanobody discovery based on yeast surface display. We provide a blueprint for identifying nanobodies, demonstrate the utility of the library by crystallizing a nanobody with its antigen, and most importantly, we utilize the platform to discover...... conformationally selective nanobodies to two distinct human GPCRs. To facilitate broad deployment of this platform, the library and associated protocols are freely available for nonprofit research....

  1. High-Level Topology-Oblivious Optimization of MPI Broadcast Algorithms on Extreme-Scale Platforms

    KAUST Repository

    Hasanov, Khalid

    2014-01-01

    There has been a significant research in collective communication operations, in particular in MPI broadcast, on distributed memory platforms. Most of the research works are done to optimize the collective operations for particular architectures by taking into account either their topology or platform parameters. In this work we propose a very simple and at the same time general approach to optimize legacy MPI broadcast algorithms, which are widely used in MPICH and OpenMPI. Theoretical analysis and experimental results on IBM BlueGene/P and a cluster of Grid’5000 platform are presented.

  2. The smartphone as a platform for wearable cameras in health research.

    Science.gov (United States)

    Gurrin, Cathal; Qiu, Zhengwei; Hughes, Mark; Caprani, Niamh; Doherty, Aiden R; Hodges, Steve E; Smeaton, Alan F

    2013-03-01

    The Microsoft SenseCam, a small camera that is worn on the chest via a lanyard, increasingly is being deployed in health research. However, the SenseCam and other wearable cameras are not yet in widespread use because of a variety of factors. It is proposed that the ubiquitous smartphones can provide a more accessible alternative to SenseCam and similar devices. To perform an initial evaluation of the potential of smartphones to become an alternative to a wearable camera such as the SenseCam. In 2012, adults were supplied with a smartphone, which they wore on a lanyard, that ran life-logging software. Participants wore the smartphone for up to 1 day and the resulting life-log data were both manually annotated and automatically analyzed for the presence of visual concepts. The results were compared to prior work using the SenseCam. In total, 166,000 smartphone photos were gathered from 47 individuals, along with associated sensor readings. The average time spent wearing the device across all users was 5 hours 39 minutes (SD=4 hours 11 minutes). A subset of 36,698 photos was selected for manual annotation by five researchers. Software analysis of these photos supports the automatic identification of activities to a similar level of accuracy as for SenseCam images in a previous study. Many aspects of the functionality of a SenseCam largely can be replicated, and in some cases enhanced, by the ubiquitous smartphone platform. This makes smartphones good candidates for a new generation of wearable sensing devices in health research, because of their widespread use across many populations. It is envisioned that smartphones will provide a compelling alternative to the dedicated SenseCam hardware for a number of users and application areas. This will be achieved by integrating new types of sensor data, leveraging the smartphone's real-time connectivity and rich user interface, and providing support for a range of relatively sophisticated applications. Copyright © 2013

  3. Advances in product family and product platform design methods & applications

    CERN Document Server

    Jiao, Jianxin; Siddique, Zahed; Hölttä-Otto, Katja

    2014-01-01

    Advances in Product Family and Product Platform Design: Methods & Applications highlights recent advances that have been made to support product family and product platform design and successful applications in industry. This book provides not only motivation for product family and product platform design—the “why” and “when” of platforming—but also methods and tools to support the design and development of families of products based on shared platforms—the “what”, “how”, and “where” of platforming. It begins with an overview of recent product family design research to introduce readers to the breadth of the topic and progresses to more detailed topics and design theory to help designers, engineers, and project managers plan, architect, and implement platform-based product development strategies in their companies. This book also: Presents state-of-the-art methods and tools for product family and product platform design Adopts an integrated, systems view on product family and pro...

  4. Modal shapes optimization and feasibility analysis of NFAL platform

    Directory of Open Access Journals (Sweden)

    Bin WEI

    2017-08-01

    Full Text Available In order to avoid friction and scratching between the conveyor and the precision components when conveying object, an compact non-contact acoustic levitation prototype is designed, and the feasibility is theoretically and experimentally verified. The symmetry model is established through kinetic analysis with ANSYS. The modal and the coupled field computation at the central point of the transfer platform are simulated. The simulation results show that pure flexural or mixed flexural wave shapes appear with different wave numbers on the platform. Sweep frequency test is conducted on the compact platform prototype. The levitation experimental results confirm the feasibility of the ultrasound transfer process, the levitation frequency range and the mode of vibration. The theoretical and experimental results show that the optimal design of the modal and the carrying capacity of the driving platform is necessary according to different conditions. The research results provide a reference for the design of the mode and bandwidth of the ultrasonic levitation platform.

  5. Implementation and validation of a model of the MPI Stewart platform

    NARCIS (Netherlands)

    Nieuwenhuizen, F.M.; Van Paasen, M.M.; Mulder, M.; Bülthoff, H.H.

    2010-01-01

    A simulated model of the MPI Stewart platform can be used to identify the influence of motion system characteristics on human control behaviour in active closed-loop control experiments on the SIMONA Research Simulator. In this paper, a previously identified model of the MPI Stewart platform was

  6. Cloud Based Earth Observation Data Exploitation Platforms

    Science.gov (United States)

    Romeo, A.; Pinto, S.; Loekken, S.; Marin, A.

    2017-12-01

    and the Amazon Web Services cloud. This work will present an overview of the TEPs and the multi-cloud EO data processing platform, and discuss their main achievements and their impacts in the context of distributed Research Infrastructures such as EPOS and EOSC.

  7. Open-Source 3-D Platform for Low-Cost Scientific Instrument Ecosystem.

    Science.gov (United States)

    Zhang, C; Wijnen, B; Pearce, J M

    2016-08-01

    The combination of open-source software and hardware provides technically feasible methods to create low-cost, highly customized scientific research equipment. Open-source 3-D printers have proven useful for fabricating scientific tools. Here the capabilities of an open-source 3-D printer are expanded to become a highly flexible scientific platform. An automated low-cost 3-D motion control platform is presented that has the capacity to perform scientific applications, including (1) 3-D printing of scientific hardware; (2) laboratory auto-stirring, measuring, and probing; (3) automated fluid handling; and (4) shaking and mixing. The open-source 3-D platform not only facilities routine research while radically reducing the cost, but also inspires the creation of a diverse array of custom instruments that can be shared and replicated digitally throughout the world to drive down the cost of research and education further. © 2016 Society for Laboratory Automation and Screening.

  8. Keyword extraction, ranking, and organization for the neuroinformatics platform.

    Science.gov (United States)

    Usui, S; Palmes, P; Nagata, K; Taniguchi, T; Ueda, N

    2007-04-01

    Brain-related researches encompass many fields of studies and usually involve worldwide collaborations. Recognizing the value of these international collaborations for efficient use of resources and improving the quality of brain research, the International Neuroinformatics Coordinating Facility (INCF) started to coordinate the effort of establishing neuroinformatics (NI) centers and portal sites among the different participating countries. These NI centers and portal sites will serve as the conduit for the interchange of information and brain-related resources among different countries. In Japan, several NI platforms under the support of NIJC (NI Japan Center) are being developed with one platform called, Visiome, already operating and publicly accessible at "http://www.platform.visiome.org". Each of these platforms requires their own set of keywords that represent important terms covering their respective fields of study. One important function of this predefined keyword list is to help contributors classify the contents of their contributions and group related resources. It is vital, therefore, that this predefined list should be properly chosen to cover the necessary areas. Currently, the process of identifying these appropriate keywords relies on the availability of human experts which does not scale well considering that different areas are rapidly evolving. This problem prompted us to develop a tool to automatically filter the most likely terms preferred by human experts. We tested the effectiveness of the proposed approach using the abstracts of the Vision Research Journal (VR) and Investigative Ophthalmology and Visual Science Journal (IOVS) as source files.

  9. The novel cloud application technology with virtual platform

    Directory of Open Access Journals (Sweden)

    Chen Ying-Chuan

    2018-01-01

    Full Text Available Virtualization technology of cloud application service is the major research issue in recent years. Our virtual platform can obtain a lot of advantages base on virtualization technology with suitable virtual machine solution that all system resources can deployed quickly and managed competently, and it has some features including the high capacity for reliability, elasticity and customization. In our virtual platform, there are many different application services are provided for cloud service style. For system computing resources, we need to share all of system and software resources using the virtualization technology is presented in related sections, and we proposed virtual and remote application technology to implement innovative, convenient and powerful cloud application service base on virtual platform. For users of our platform, they can easy to use any software and tools on demand with pay per use mode anytime, and they do not have specialized knowledge and ability of install and maintenance.

  10. Web Platform for Sharing Modeling Software in the Field of Nonlinear Optics

    Directory of Open Access Journals (Sweden)

    Dubenskaya Julia

    2018-01-01

    Full Text Available We describe the prototype of a Web platform intended for sharing software programs for computer modeling in the rapidly developing field of the nonlinear optics phenomena. The suggested platform is built on the top of the HUBZero open-source middleware. In addition to the basic HUBZero installation we added to our platform the capability to run Docker containers via an external application server and to send calculation programs to those containers for execution. The presented web platform provides a wide range of features and might be of benefit to nonlinear optics researchers.

  11. Web Platform for Sharing Modeling Software in the Field of Nonlinear Optics

    Science.gov (United States)

    Dubenskaya, Julia; Kryukov, Alexander; Demichev, Andrey

    2018-02-01

    We describe the prototype of a Web platform intended for sharing software programs for computer modeling in the rapidly developing field of the nonlinear optics phenomena. The suggested platform is built on the top of the HUBZero open-source middleware. In addition to the basic HUBZero installation we added to our platform the capability to run Docker containers via an external application server and to send calculation programs to those containers for execution. The presented web platform provides a wide range of features and might be of benefit to nonlinear optics researchers.

  12. Users and Programmers Guide for HPC Platforms in CIEMAT

    International Nuclear Information System (INIS)

    Munoz Roldan, A.

    2003-01-01

    This Technical Report presents a description of the High Performance Computing platforms available to researchers in CIEMAT and dedicated mainly to scientific computing. It targets to users and programmers and tries to help in the processes of developing new code and porting code across platforms. A brief review is also presented about historical evolution in the field of HPC, ie, the programming paradigms and underlying architectures. (Author) 32 refs

  13. Platform-based production development

    DEFF Research Database (Denmark)

    Bossen, Jacob; Brunoe, Thomas Ditlev; Nielsen, Kjeld

    2015-01-01

    Platforms as a means for applying modular thinking in product development is relatively well studied, but platforms in the production system has until now not been given much attention. With the emerging concept of platform-based co-development the importance of production platforms is though...

  14. Industry Platforms and New Industrial Policy in Russia

    Directory of Open Access Journals (Sweden)

    Svetlana V. Orekhova

    2017-12-01

    Full Text Available The article aims at clarifying Russian industrial policy as a result of business models changing and market reconstruction. The research bass on the hypothesis that the choice of the industrial policy administrative measures depends on the object of management. It is important to link government regulation of markets with corporate strategies. We reveal that modern economic systems based on using of electronic technologies, big data, and innovative activity. Technological platforms as the single organizational and economic mechanisms affect economic systems very much. We study the content and main characteristics of a business model, is called the "technological platform". We also identify the main required changes in industrial policy. We analyze the matching between scientific and technological scenarios of the Russian economic development and the technological platform. There are two areas of the new industrial policy. They are: a multi-sectoral approach to regulating and improving the quality of the national institutional environment. The industrial and cluster management approaches are inefficient in modern conditions. There is a need for each platform of its technological development scenario. We also clarify the role of the state in the functioning of technological platforms.

  15. Omnidirectional holonomic platforms

    International Nuclear Information System (INIS)

    Pin, F.G.; Killough, S.M.

    1994-01-01

    This paper presents the concepts for a new family of wheeled platforms which feature full omnidirectionality with simultaneous and independently controlled rotational and translational motion capabilities. The authors first present the orthogonal-wheels concept and the two major wheel assemblies on which these platforms are based. They then describe how a combination of these assemblies with appropriate control can be used to generate an omnidirectional capability for mobile robot platforms. The design and control of two prototype platforms are then presented and their respective characteristics with respect to rotational and translational motion control are discussed

  16. Platform decommissioning costs

    International Nuclear Information System (INIS)

    Rodger, David

    1998-01-01

    There are over 6500 platforms worldwide contributing to the offshore oil and gas production industry. In the North Sea there are around 500 platforms in place. There are many factors to be considered in planning for platform decommissioning and the evaluation of options for removal and disposal. The environmental impact, technical feasibility, safety and cost factors all have to be considered. This presentation considers what information is available about the overall decommissioning costs for the North Sea and the costs of different removal and disposal options for individual platforms. 2 figs., 1 tab

  17. Globus Nexus: A Platform-as-a-Service Provider of Research Identity, Profile, and Group Management.

    Science.gov (United States)

    Chard, Kyle; Lidman, Mattias; McCollam, Brendan; Bryan, Josh; Ananthakrishnan, Rachana; Tuecke, Steven; Foster, Ian

    2016-03-01

    Globus Nexus is a professionally hosted Platform-as-a-Service that provides identity, profile and group management functionality for the research community. Many collaborative e-Science applications need to manage large numbers of user identities, profiles, and groups. However, developing and maintaining such capabilities is often challenging given the complexity of modern security protocols and requirements for scalable, robust, and highly available implementations. By outsourcing this functionality to Globus Nexus, developers can leverage best-practice implementations without incurring development and operations overhead. Users benefit from enhanced capabilities such as identity federation, flexible profile management, and user-oriented group management. In this paper we present Globus Nexus, describe its capabilities and architecture, summarize how several e-Science applications leverage these capabilities, and present results that characterize its scalability, reliability, and availability.

  18. Globus Nexus: A Platform-as-a-Service provider of research identity, profile, and group management

    Energy Technology Data Exchange (ETDEWEB)

    Chard, Kyle; Lidman, Mattias; McCollam, Brendan; Bryan, Josh; Ananthakrishnan, Rachana; Tuecke, Steven; Foster, Ian

    2016-03-01

    Globus Nexus is a professionally hosted Platform-as-a-Service that provides identity, profile and group management functionality for the research community. Many collaborative e-Science applications need to manage large numbers of user identities, profiles, and groups. However, developing and maintaining such capabilities is often challenging given the complexity of modern security protocols and requirements for scalable, robust, and highly available implementations. By outsourcing this functionality to Globus Nexus, developers can leverage best-practice implementations without incurring development and operations overhead. Users benefit from enhanced capabilities such as identity federation, flexible profile management, and user-oriented group management. In this paper we present Globus Nexus, describe its capabilities and architecture, summarize how several e-Science applications leverage these capabilities, and present results that characterize its scalability, reliability, and availability.

  19. From Idea to Market: A Review of the Spanish Technology Platforms

    Energy Technology Data Exchange (ETDEWEB)

    Castaño Marín, M.L.

    2016-07-01

    The European Commission and Member States have launched ifferent measures within the European Research Area in order to improve the well-being of the citizens and the competitiveness of Europe. The Spanish Technology Platforms have proven to be a successful instrument of public-private cooperation and play a role in key areas of innovation for economic development. Following the steps of the European Technology Platform, Spain supported the creation of an important network of National Technology Platforms. The Spanish Technology Platforms have adapted efficiently to the changes of the R&D&I system and nowadays they are a key instrument to build an economic model based on knowledge.

  20. NERIS: European platform on preparedness for nuclear and radiological emergency response and recovery

    International Nuclear Information System (INIS)

    Duranova, T.; Bohunova, J.; Schneider, T.; Biduener, S.; Badelay, J.; Gallego, E.; Gering, F.; Hrdeman, F.; Dubreuil, G.; Murith, Ch.; Oughton, D.; Raskob, W.

    2014-01-01

    The NERIS platform was established in June 2010 to encourage European, national, regional and local authorities, technical support organisation, operators, professional organisations, research institutes, universities, and non-governmental organisations to cooperate and to facilitate access expertise and technology in maintaining competence in the field of nuclear emergency management and recovery for the benefit of European countries and citizens. 49 organisations are members of the NERIS Platform from 24 countries and 20 members are supporting organisations. The NERIS Association has been registered in August 2012 as a legal European Association under the French Law. It is operated by a management board of 10 members and the NERIS R and D Committee elaborates its strategic orientation. The NERIS Platform is linked to research projects, managed by KIT: - NERIS TP 'Towards a self sustaining European Technology Platform on Preparedness for Nuclear and Radiological Emergency Response and Recovery'. - PREPARE project on innovative integrative tools and platforms to be prepared for radiological emergencies and post-accident response in Europe. To set up a common reflection, cooperation have been established with European and international organisations: HERCA, ALLIANCE, CRPPH, ICRP and AIEA. To share issues on lessons learnt from the Fukushima accident, cooperation have been initiated with IGES (Institute for Global Environment Strategies) and with the Fukushima University. The NERIS Platform is also involved in the steering committee of the EC Project OPERRA, aiming at structuring the research in the field of radiation protection at the Horizon 2020. This paper will present the key components of the NERIS Platform and its objectives. (authors)

  1. Product Platform Replacements

    DEFF Research Database (Denmark)

    Sköld, Martin; Karlsson, Christer

    2012-01-01

    . To shed light on this unexplored and growing managerial concern, the purpose of this explorative study is to identify operational challenges to management when product platforms are replaced. Design/methodology/approach – The study uses a longitudinal field-study approach. Two companies, Gamma and Omega...... replacement was chosen in each company. Findings – The study shows that platform replacements primarily challenge managers' existing knowledge about platform architectures. A distinction can be made between “width” and “height” in platform replacements, and it is crucial that managers observe this in order...... to challenge their existing knowledge about platform architectures. Issues on technologies, architectures, components and processes as well as on segments, applications and functions are identified. Practical implications – Practical implications are summarized and discussed in relation to a framework...

  2. Smart Makerspace: A Web Platform Implementation

    Directory of Open Access Journals (Sweden)

    Gabriel Licks

    2018-02-01

    Full Text Available Makerspaces are creative and learning environments, home to activities such as fabrication processes and Do-It-Yourself (DIY tasks. However, containing equipment that are not commonly seen or handled, these spaces can look rather challenging to novice users. This paper is based on the Smart Makerspace research from Autodesk, which uses a smart workbench for an immersive instructional space for DIY tasks. Having its functionalities in mind and trying to overcome some of its limitations, we approach the concept building an immersive instructional space as a web platform. The platform, introduced to users in a makerspace, had a feedback that reflects its potential between novice and intermediate users, for creating facilitators and encouraging these users.

  3. Opening access to African scholarly content: Stellenbosch University's AOARI platforms

    Directory of Open Access Journals (Sweden)

    Dr Reggie Raju

    2013-03-01

    Full Text Available Africa is viewed as a consumer of the world's knowledge production. A significant factor influencing this status is the low research output, with the main contributor to this status being minimum access to scholarly content to support research. Stellenbosch University, a leading research institution on the African continent, is committed to contributing to changing this status quo through the distribution of its own research output utilizing open sources. Given the challenges that have plagued Africa in developing processes for the distribution of their research, Stellenbosch University has developed the African Open Access Repository Initiative (AOARI which uses open source software for two platforms that support the ‘green’ and ‘gold’ route to sharing scholarly literature: Ubuntu is used as the operating system, DSpace is used for its repository and Open Journal Systems for its publication platform. It is anticipated that AOARI will be the bridge that facilitates the sharing of research output and nurtures a culture of research production in Africa.

  4. A Comparative Analysis of MOOC (Massive Open Online Course Platforms

    Directory of Open Access Journals (Sweden)

    Maria CONACHE

    2016-01-01

    Full Text Available The MOOC platforms have known a considerable development in recent years due to the enlargement of online space and the shifting between traditional to virtual activities. These plat-forms made it possible for people almost everywhere to take online academic courses offered by top universities via open access to web and with unlimited participation. Thus, it came naturally to us to address the question what makes them so successful? The purpose of this paper is to report comparatively MOOC platforms in terms of features, based on the user’s implication and demands. First, we chose four relevant lifelong learning platforms and then we structured three main categories for the platforms' qualification, depending on which we built our theory regarding the comparison between them. Our analysis consists of three sets of criteria: business model, course design and popularity among online users. Starting from this perspective, we built a range of representative factors for which we highlighted the major aspects for each plat-form in our comparative research

  5. Using and Designing Platforms for In Vivo Education Experiments

    OpenAIRE

    Williams, Joseph Jay; Ostrow, Korinn; Xiong, Xiaolu; Glassman, Elena; Kim, Juho; Maldonado, Samuel G.; Li, Na; Reich, Justin; Hefferman, Neil

    2015-01-01

    In contrast to typical laboratory experiments, the everyday use of online educational resources by large populations and the prevalence of software infrastructure for A/B testing leads us to consider how platforms can embed in vivo experiments that do not merely support research, but ensure practical improvements to their educational components. Examples are presented of randomized experimental comparisons conducted by subsets of the authors in three widely used online educational platforms K...

  6. High resolution data from everyday life: coproducing a technically robust and engaging sensing platform

    Directory of Open Access Journals (Sweden)

    Matthew Machin

    2017-04-01

    We found it was feasible to integrate requirements from both researchers and patients when developing a sensing platform for dementia research. By seeking feedback from both user groups, we were better able to attend to device linkage requirements, platform functionality and acceptability, integrating these within development and procurement processes. Furthermore, we identified aspects of research setup and design that could support sustained engagement from participants, thereby improving data completeness and quality.

  7. Learning Management Platform for CyberCIEGE

    Science.gov (United States)

    2011-12-01

    CLE is a platform that allows academic and research collaboration and it is built on open pedagogy and open standard [16]. In those situations...C. Irvine, “Active learning with the CyberCIEGE video game,” in Proceedings of the 4th Conference on Cyber Security Experimentation and Test, 2011

  8. Developing an Open Source, Reusable Platform for Distributed Collaborative Information Management in the Early Detection Research Network

    Science.gov (United States)

    Hart, Andrew F.; Verma, Rishi; Mattmann, Chris A.; Crichton, Daniel J.; Kelly, Sean; Kincaid, Heather; Hughes, Steven; Ramirez, Paul; Goodale, Cameron; Anton, Kristen; hide

    2012-01-01

    For the past decade, the NASA Jet Propulsion Laboratory, in collaboration with Dartmouth University has served as the center for informatics for the Early Detection Research Network (EDRN). The EDRN is a multi-institution research effort funded by the U.S. National Cancer Institute (NCI) and tasked with identifying and validating biomarkers for the early detection of cancer. As the distributed network has grown, increasingly formal processes have been developed for the acquisition, curation, storage, and dissemination of heterogeneous research information assets, and an informatics infrastructure has emerged. In this paper we discuss the evolution of EDRN informatics, its success as a mechanism for distributed information integration, and the potential sustainability and reuse benefits of emerging efforts to make the platform components themselves open source. We describe our experience transitioning a large closed-source software system to a community driven, open source project at the Apache Software Foundation, and point to lessons learned that will guide our present efforts to promote the reuse of the EDRN informatics infrastructure by a broader community.

  9. Application of GNSS Methods for Monitoring Offshore Platform Deformation

    Science.gov (United States)

    Myint, Khin Cho; Nasir Matori, Abd; Gohari, Adel

    2018-03-01

    Global Navigation Satellite System (GNSS) has become a powerful tool for high-precision deformation monitoring application. Monitoring of deformation and subsidence of offshore platform due to factors such as shallow gas phenomena. GNSS is the technical interoperability and compatibility between various satellite navigation systems such as modernized GPS, Galileo, reconstructed GLONASS to be used by civilian users. It has been known that excessive deformation affects platform structurally, causing loss of production and affects the efficiency of the machinery on board the platform. GNSS have been proven to be one of the most precise positioning methods where by users can get accuracy to the nearest centimeter of a given position from carrier phase measurement processing of GPS signals. This research is aimed at using GNSS technique, which is one of the most standard methods to monitor the deformation of offshore platforms. Therefore, station modeling, which accounts for the spatial correlated errors, and hence speeds up the ambiguity resolution process is employed. It was found that GNSS combines the high accuracy of the results monitoring the offshore platforms deformation with the possibility of survey.

  10. SciLite: a platform for displaying text-mined annotations as a means to link research articles with biological data

    Science.gov (United States)

    Talo, Francesco; Ide-Smith, Michele; Gobeill, Julien; Carter, Jacob; Batista-Navarro, Riza; Ananiadou, Sophia; Ruch, Patrick; McEntyre, Johanna

    2017-01-01

    The tremendous growth in biological data has resulted in an increase in the number of research papers being published. This presents a great challenge for scientists in searching and assimilating facts described in those papers. Particularly, biological databases depend on curators to add highly precise and useful information that are usually extracted by reading research articles. Therefore, there is an urgent need to find ways to improve linking literature to the underlying data, thereby minimising the effort in browsing content and identifying key biological concepts.   As part of the development of Europe PMC, we have developed a new platform, SciLite, which integrates text-mined annotations from different sources and overlays those outputs on research articles. The aim is to aid researchers and curators using Europe PMC in finding key concepts more easily and provide links to related resources or tools, bridging the gap between literature and biological data. PMID:28948232

  11. Product Platform Modeling

    DEFF Research Database (Denmark)

    Pedersen, Rasmus

    for customisation of products. In many companies these changes in the business environment have created a controversy between the need for a wide variety of products offered to the marketplace and a desire to reduce variation within the company in order to increase efficiency. Many companies use the concept...... other. These groups can be varied and combined to form different product variants without increasing the internal variety in the company. Based on the Theory of Domains, the concept of encapsulation in the organ domain is introduced, and organs are formulated as platform elements. Included......This PhD thesis has the title Product Platform Modelling. The thesis is about product platforms and visual product platform modelling. Product platforms have gained an increasing attention in industry and academia in the past decade. The reasons are many, yet the increasing globalisation...

  12. An open-access platform for camera-trapping data

    Directory of Open Access Journals (Sweden)

    Mario César Lavariega

    2018-02-01

    Full Text Available In southern Mexico, local communities have been playing important roles in the design and collection of wildlife data through camera-trapping in community-based monitoring of biodiversity projects. However, the methods used to store the data have limited their use in matters of decision-making and research. Thus, we present the Platform for Community-based Monitoring of Biodiversity (PCMB, a repository, which allows storage, visualization, and downloading of photographs captured by community-based monitoring of biodiversity projects in protected areas of southern Mexico. The platform was developed using agile software development with extensive interaction between computer scientists and biologists. System development included gathering data, design, built, database and attributes creation, and quality control. The PCMB currently contains 28,180 images of 6478 animals (69.4% mammals and 30.3% birds. Of the 32 species of mammals recorded in 18 PA since 2012, approximately a quarter of all photographs were of white-tailed deer (Odocoileus virginianus. Platforms permitting access to camera-trapping data are a valuable step in opening access to data of biodiversity; the PCMB is a practical new tool for wildlife management and research with data generated through local participation. Thus, this work encourages research on the data generated through the community-based monitoring of biodiversity projects in protected areas, to provide an important information infrastructure for effective management and conservation of wildlife.

  13. Using Social Media as a Managerial Platform for an Educational Development Project : Cofimvaba

    CSIR Research Space (South Africa)

    Van der Vyver, AG

    2015-12-01

    Full Text Available of the project use Whatsapp, a popular social media platform to engage in managerial communication. The researchers found that this unconventional platform proved to be an excellent anchor for managerial communication on the project....

  14. The design and implementation of a network simulation platform

    CSIR Research Space (South Africa)

    Von Solms, S

    2013-11-01

    Full Text Available these events and their effects can enable researchers to identify these threats and find ways to counter them. In this paper we present the design of a network simulation platform which can enable researchers to study dynamic behaviour of networks, network...

  15. SeqHound: biological sequence and structure database as a platform for bioinformatics research

    Directory of Open Access Journals (Sweden)

    Dumontier Michel

    2002-10-01

    Full Text Available Abstract Background SeqHound has been developed as an integrated biological sequence, taxonomy, annotation and 3-D structure database system. It provides a high-performance server platform for bioinformatics research in a locally-hosted environment. Results SeqHound is based on the National Center for Biotechnology Information data model and programming tools. It offers daily updated contents of all Entrez sequence databases in addition to 3-D structural data and information about sequence redundancies, sequence neighbours, taxonomy, complete genomes, functional annotation including Gene Ontology terms and literature links to PubMed. SeqHound is accessible via a web server through a Perl, C or C++ remote API or an optimized local API. It provides functionality necessary to retrieve specialized subsets of sequences, structures and structural domains. Sequences may be retrieved in FASTA, GenBank, ASN.1 and XML formats. Structures are available in ASN.1, XML and PDB formats. Emphasis has been placed on complete genomes, taxonomy, domain and functional annotation as well as 3-D structural functionality in the API, while fielded text indexing functionality remains under development. SeqHound also offers a streamlined WWW interface for simple web-user queries. Conclusions The system has proven useful in several published bioinformatics projects such as the BIND database and offers a cost-effective infrastructure for research. SeqHound will continue to develop and be provided as a service of the Blueprint Initiative at the Samuel Lunenfeld Research Institute. The source code and examples are available under the terms of the GNU public license at the Sourceforge site http://sourceforge.net/projects/slritools/ in the SLRI Toolkit.

  16. Introducing Platform Interactions Model for Studying Multi-Sided Platforms

    DEFF Research Database (Denmark)

    Staykova, Kalina; Damsgaard, Jan

    2018-01-01

    Multi-Sided Platforms (MSPs) function as socio-technical entities that facilitate direct interactions between various affiliated to them constituencies through developing and managing IT architecture. In this paper, we aim to explain the nature of the platform interactions as key characteristic o...

  17. Energy modelling platforms for policy and strategy support

    International Nuclear Information System (INIS)

    Dyner, I.

    2000-01-01

    The energy field has been dominated by 'hard' modelling approaches by researchers from engineering and economics discipline. The recent trend towards a more liberalised environment moves away from central planning to market-based resource allocation, leading to the creation and use of strategic tools, with much 'softer' specifications, in the 'system-thinking' tradition. This paper presents the use of system dynamics in a generalised way, to provide a platform for integrated energy analysis. Issues of modularity and policy evolution are important in the design of the modelling platform to facilitate its use, and reuse. Hence the concepts of a platform, rather than a model, has to be implemented in a coherent way if it is to provide sustained value for ongoing support to both government policy and corporate strategy. (author)

  18. Business analysis for a sustainable, multi-stakeholder ecosystem for leveraging the Electronic Health Records for Clinical Research (EHR4CR) platform in Europe.

    Science.gov (United States)

    Dupont, Danielle; Beresniak, Ariel; Sundgren, Mats; Schmidt, Andreas; Ainsworth, John; Coorevits, Pascal; Kalra, Dipak; Dewispelaere, Marc; De Moor, Georges

    2017-01-01

    The Electronic Health Records for Clinical Research (EHR4CR) technological platform has been developed to enable the trustworthy reuse of hospital electronic health records data for clinical research. The EHR4CR platform can enhance and speed up clinical research scenarios: protocol feasibility assessment, patient identification for recruitment in clinical trials, and clinical data exchange, including for reporting serious adverse events. Our objective was to seed a multi-stakeholder ecosystem to enable the scalable exploitation of the EHR4CR platform in Europe, and to assess its economic sustainability. Market analyses were conducted by a multidisciplinary task force to define an EHR4CR emerging ecosystem and multi-stakeholder value chain. This involved mapping stakeholder groups and defining their unmet needs, incentives, potential barriers for adopting innovative solutions, roles and interdependencies. A comprehensive business model, value propositions, and sustainability strategies were developed accordingly. Using simulation modelling (including Monte Carlo simulations) and a 5-year horizon, the potential financial outcomes of the business model were forecasted from the perspective of an EHR4CR service provider. A business ecosystem was defined to leverage the EHR4CR multi-stakeholder value chain. Value propositions were developed describing the expected benefits of EHR4CR solutions for all stakeholders. From an EHR4CR service provider's viewpoint, the business model simulation estimated that a profitability ratio of up to 1.8 could be achieved at year 1, with potential for growth in subsequent years depending on projected market uptake. By enhancing and speeding up existing processes, EHR4CR solutions promise to transform the clinical research landscape. The ecosystem defined provides the organisational framework for optimising the value and benefits for all stakeholders involved, in a sustainable manner. Our study suggests that the exploitation of EHR4CR

  19. Design & Evaluation of an Accessible Hybrid Violin Platform

    DEFF Research Database (Denmark)

    Overholt, Daniel; Gelineck, Steven

    2014-01-01

    We introduce and describe the initial evaluation of a new accessible (easily replicable) augmented violin prototype. Our research is focused on the user experience when playing such hybrid physical- digital instruments, and exploration of novel interactive performance techniques. The goal of wider...... platform accessibility for players and other researchers is approached via a simple ‘do-it-yourself’ design described herein. All hardware and software elements are open- source, and the build process requires minimal electronics skills. Cost has also been kept to a minimum where possible. Our initial...... that incorporates orientation/gesture sensors as well, with the resulting sound amplified and rendered via small speakers mounted directly to the instrument. The platform combines all necessary elements for digitally-mediated interactive performance; the need for a traditional computer only arises when developing...

  20. Artistic and Engineering Design of Platform-Based Production Systems: A Study of Swedish Architectural Practice

    Directory of Open Access Journals (Sweden)

    Gustav Jansson

    2018-02-01

    Full Text Available Research on platform-based production systems for house-building has focused on production and manufacturing issues. The aim of this research is to explore how the architectural design process contributes to the industrialised house-building industry from the perspective of creative design work. It also aims to describe how constraints affect architectural design work in the engineer-to-order context, when using platform-based production systems. Architects with experience in using platform-based building systems with different degrees of constraints were interviewed regarding creative aspects of the design work. The interviews, together with documents relating to platform constraints, were then analysed from the perspective of artistic and engineering design theories. The results show the benefits and issues of using platform constraints, both with prefabrication of volumetric modules, as well as prefabricated slab and wall elements. The study highlights a major research gap by describing how architectural work, from both the creative artistic and engineering design perspectives, is affected by constraints in the building platform: (1 the architectural design work goes through a series of divergent and convergent processes where the divergent processes are explorative and the convergent processes are solution-oriented; and (2, there is a trade-off between creativity and efficiency in the design work. Open parameters for layout design are key to architectural creativity, while predefinition supports efficiency. The results also provide an understanding of the potential for creativity in artistic and engineering work tasks through different phases in design, and how they are related to constraints in the platform. The main limitation of the research is the number of interviewed architects who had different background experiences of working with different types of platform constraints. More studies are needed to confirm the observations and to

  1. Energy Consumption Management of Virtual Cloud Computing Platform

    Science.gov (United States)

    Li, Lin

    2017-11-01

    For energy consumption management research on virtual cloud computing platforms, energy consumption management of virtual computers and cloud computing platform should be understood deeper. Only in this way can problems faced by energy consumption management be solved. In solving problems, the key to solutions points to data centers with high energy consumption, so people are in great need to use a new scientific technique. Virtualization technology and cloud computing have become powerful tools in people’s real life, work and production because they have strong strength and many advantages. Virtualization technology and cloud computing now is in a rapid developing trend. It has very high resource utilization rate. In this way, the presence of virtualization and cloud computing technologies is very necessary in the constantly developing information age. This paper has summarized, explained and further analyzed energy consumption management questions of the virtual cloud computing platform. It eventually gives people a clearer understanding of energy consumption management of virtual cloud computing platform and brings more help to various aspects of people’s live, work and son on.

  2. Fiscal 1999 achievement report on interuniversity coordination type research and development of industrial technology. Research and development of highly functional material designing platform; 1999 nendo kokino zairyo sekkei platform no kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    For the purpose of enabling prediction of structures and properties of polymeric materials by computer-assisted experiments, studies were conducted for putting new simulation technologies to practical application. Simulation technologies underwent research and development with working groups respectively dealing with the coarse-graining molecular dynamic method, dynamic mean field method, dispersed structure simulation, study of verification, and platform. The Faculty of Engineering, Yamagata University, succeeded in the development of a device enabling direct observation of crystallization under shear flow, which was for the construction of a material property database. The Graduate School of Frontier Sciences, University of Tokyo, developed a device for measuring dielectric relaxation under shear flow, by which findings were obtained concerning ion fluctuation and diffusion in a micellar system. The Institute of Industrial Science, University of Tokyo, studied pattern formation dynamics which involved viscoelastic phase separation in a polymeric solution whose composition was near critical. (NEDO)

  3. Design and Research on Platform to Enhance College Students’ Art Appreciation Capability Based on Modern Information Technology

    Directory of Open Access Journals (Sweden)

    Shen Xifei

    2015-01-01

    Full Text Available Nowadays, with the rapid development of modern information technology, the college students could not preferably choose and learn to enhance their own art appreciation capability. Therefore, the colleges and universities have a more urgent desire to organize, develop and provide a good platform to enhance the college students’ art appreciation capability based on modern information technology. This paper describes how to enhance the art appreciation capability in detail, and designs and analyzes the platform to enhance college students’ art appreciation capability based on modern information technology---the “Music Corner” and the “Dance Corner”, indicating that the exchange platform built with modern information technology can promotes the college students’ art appreciation capability. Finally, through the analysis of statistical results of the questionnaire, college students are fonder of art appreciation after the establishment of platform, more inclined to the comprehensive learning of art, more brave to express their own sense of art, and fonder of artistic creation.

  4. The Common Data Acquisition Platform in the Helmholtz Association

    International Nuclear Information System (INIS)

    Kaever, P.; Balzer, M.; Kopmann, A.; Zimmer, M.; Rongen, H.

    2017-01-01

    Various centres of the German Helmholtz Association (HGF) started in 2012 to develop a modular data acquisition (DAQ) platform, covering the entire range from detector readout to data transfer into parallel computing environments. This platform integrates generic hardware components like the multi-purpose HGF-Advanced Mezzanine Card or a smart scientific camera framework, adding user value with Linux drivers and board support packages. Technically the scope comprises the DAQ-chain from FPGA-modules to computing servers, notably frontend-electronics-interfaces, microcontrollers and GPUs with their software plus high-performance data transmission links. The core idea is a generic and component-based approach, enabling the implementation of specific experiment requirements with low effort. This so called DTS-platform will support standards like MTCA.4 in hard- and software to ensure compatibility with commercial components. Its capability to deploy on other crate standards or FPGA-boards with PCI express or Ethernet interfaces remains an essential feature. Competences of the participating centres are coordinated in order to provide a solid technological basis for both research topics in the Helmholtz Programme ''Matter and Technology'': ''Detector Technology and Systems'' and ''Accelerator Research and Development''. The DTS-platform aims at reducing costs and development time and will ensure access to latest technologies for the collaboration. Due to its flexible approach, it has the potential to be applied in other scientific programs.

  5. The Common Data Acquisition Platform in the Helmholtz Association

    Science.gov (United States)

    Kaever, P.; Balzer, M.; Kopmann, A.; Zimmer, M.; Rongen, H.

    2017-04-01

    Various centres of the German Helmholtz Association (HGF) started in 2012 to develop a modular data acquisition (DAQ) platform, covering the entire range from detector readout to data transfer into parallel computing environments. This platform integrates generic hardware components like the multi-purpose HGF-Advanced Mezzanine Card or a smart scientific camera framework, adding user value with Linux drivers and board support packages. Technically the scope comprises the DAQ-chain from FPGA-modules to computing servers, notably frontend-electronics-interfaces, microcontrollers and GPUs with their software plus high-performance data transmission links. The core idea is a generic and component-based approach, enabling the implementation of specific experiment requirements with low effort. This so called DTS-platform will support standards like MTCA.4 in hard- and software to ensure compatibility with commercial components. Its capability to deploy on other crate standards or FPGA-boards with PCI express or Ethernet interfaces remains an essential feature. Competences of the participating centres are coordinated in order to provide a solid technological basis for both research topics in the Helmholtz Programme ``Matter and Technology'': ``Detector Technology and Systems'' and ``Accelerator Research and Development''. The DTS-platform aims at reducing costs and development time and will ensure access to latest technologies for the collaboration. Due to its flexible approach, it has the potential to be applied in other scientific programs.

  6. GATECloud.net: a platform for large-scale, open-source text processing on the cloud.

    Science.gov (United States)

    Tablan, Valentin; Roberts, Ian; Cunningham, Hamish; Bontcheva, Kalina

    2013-01-28

    Cloud computing is increasingly being regarded as a key enabler of the 'democratization of science', because on-demand, highly scalable cloud computing facilities enable researchers anywhere to carry out data-intensive experiments. In the context of natural language processing (NLP), algorithms tend to be complex, which makes their parallelization and deployment on cloud platforms a non-trivial task. This study presents a new, unique, cloud-based platform for large-scale NLP research--GATECloud. net. It enables researchers to carry out data-intensive NLP experiments by harnessing the vast, on-demand compute power of the Amazon cloud. Important infrastructural issues are dealt with by the platform, completely transparently for the researcher: load balancing, efficient data upload and storage, deployment on the virtual machines, security and fault tolerance. We also include a cost-benefit analysis and usage evaluation.

  7. A Research on the Model of Network Lending Platform in China

    OpenAIRE

    Li, Ying; Kobayashi, Mamoru

    2017-01-01

    In 1974, Professor Yunus has built microfinance institutions to alleviate poverty in Bangladesh, soon the microcredit model has gradually expanded around the world. In recent years, with the continuous innovation and development of the Internet and Mobile Internet, a variety of online platforms are growing rapidly and widely, As the economic and the continuous progresses on network technology have developed rapidly, Internet technology has quickly melt into the financial industry, Internet ne...

  8. NERIS: The European platform on preparedness for nuclear and radiological emergency response and recovery

    International Nuclear Information System (INIS)

    Duranova, T.; Bohunova, J.; Schneider, T.; Biduener, S.; Badelay, J.; Gallego, E.; Gering, F.; Hrdeman, F.; Dubreuil, G.; Murith, Ch.; Oughton, D.; Raskob, W.

    2014-01-01

    The NERIS platform was established in June 2010 to encourage European, national, regional and local authorities, technical support organisation, operators, professional organisations, research institutes, universities, and non-governmental organisations to cooperate and to facilitate access expertise and technology in maintaining competence in the field of nuclear emergency management and recovery for the benefit of European countries and citizens. 49 organisations are members of the NERIS Platform from 24 countries and 20 members are supporting organisations. The NERIS Association has been registered in August 2012 as a legal European Association under the French Law. It is operated by a management board of 10 members and the NERIS R and D Committee elaborates its strategic orientation. The NERIS Platform is linked to research projects, managed by KIT: - NERIS TP 'Towards a self sustaining European Technology Platform on Preparedness for Nuclear and Radiological Emergency Response and Recovery'. - PREPARE project on innovative integrative tools and platforms to be prepared for radiological emergencies and post-accident response in Europe. To set up a common reflection, cooperations have been established with European and international organisations: HERCA, ALLIANCE, CRPPH, ICRP and AIEA. To share issues on lessons learnt from the Fukushima accident, cooperation have been initiated with IGES (Institute for Global Environment Strategies) and with the Fukushima University. The NERIS Platform is also involved in the steering committee of the EC Project OPERRA, aiming at structuring the research in the field of radiation protection at the Horizon 2020. This paper will present the key components of the NERIS Platform and its objectives. (authors)

  9. Open-WiSe: A Solar Powered Wireless Sensor Network Platform

    Science.gov (United States)

    González, Apolinar; Aquino, Raúl; Mata, Walter; Ochoa, Alberto; Saldaña, Pedro; Edwards, Arthur

    2012-01-01

    Because battery-powered nodes are required in wireless sensor networks and energy consumption represents an important design consideration, alternate energy sources are needed to provide more effective and optimal function. The main goal of this work is to present an energy harvesting wireless sensor network platform, the Open Wireless Sensor node (WiSe). The design and implementation of the solar powered wireless platform is described including the hardware architecture, firmware, and a POSIX Real-Time Kernel. A sleep and wake up strategy was implemented to prolong the lifetime of the wireless sensor network. This platform was developed as a tool for researchers investigating Wireless sensor network or system integrators. PMID:22969396

  10. Open-WiSe: a solar powered wireless sensor network platform.

    Science.gov (United States)

    González, Apolinar; Aquino, Raúl; Mata, Walter; Ochoa, Alberto; Saldaña, Pedro; Edwards, Arthur

    2012-01-01

    Because battery-powered nodes are required in wireless sensor networks and energy consumption represents an important design consideration, alternate energy sources are needed to provide more effective and optimal function. The main goal of this work is to present an energy harvesting wireless sensor network platform, the Open Wireless Sensor node (WiSe). The design and implementation of the solar powered wireless platform is described including the hardware architecture, firmware, and a POSIX Real-Time Kernel. A sleep and wake up strategy was implemented to prolong the lifetime of the wireless sensor network. This platform was developed as a tool for researchers investigating Wireless sensor network or system integrators.

  11. A Platform for Scalable Satellite and Geospatial Data Analysis

    Science.gov (United States)

    Beneke, C. M.; Skillman, S.; Warren, M. S.; Kelton, T.; Brumby, S. P.; Chartrand, R.; Mathis, M.

    2017-12-01

    At Descartes Labs, we use the commercial cloud to run global-scale machine learning applications over satellite imagery. We have processed over 5 Petabytes of public and commercial satellite imagery, including the full Landsat and Sentinel archives. By combining open-source tools with a FUSE-based filesystem for cloud storage, we have enabled a scalable compute platform that has demonstrated reading over 200 GB/s of satellite imagery into cloud compute nodes. In one application, we generated global 15m Landsat-8, 20m Sentinel-1, and 10m Sentinel-2 composites from 15 trillion pixels, using over 10,000 CPUs. We recently created a public open-source Python client library that can be used to query and access preprocessed public satellite imagery from within our platform, and made this platform available to researchers for non-commercial projects. In this session, we will describe how you can use the Descartes Labs Platform for rapid prototyping and scaling of geospatial analyses and demonstrate examples in land cover classification.

  12. The Prodiguer Messaging Platform

    Science.gov (United States)

    Denvil, S.; Greenslade, M. A.; Carenton, N.; Levavasseur, G.; Raciazek, J.

    2015-12-01

    CONVERGENCE is a French multi-partner national project designed to gather HPC and informatics expertise to innovate in the context of running French global climate models with differing grids and at differing resolutions. Efficient and reliable execution of these models and the management and dissemination of model output are some of the complexities that CONVERGENCE aims to resolve.At any one moment in time, researchers affiliated with the Institut Pierre Simon Laplace (IPSL) climate modeling group, are running hundreds of global climate simulations. These simulations execute upon a heterogeneous set of French High Performance Computing (HPC) environments. The IPSL's simulation execution runtime libIGCM (library for IPSL Global Climate Modeling group) has recently been enhanced so as to support hitherto impossible realtime use cases such as simulation monitoring, data publication, metrics collection, simulation control, visualizations … etc. At the core of this enhancement is Prodiguer: an AMQP (Advanced Message Queue Protocol) based event driven asynchronous distributed messaging platform. libIGCM now dispatches copious amounts of information, in the form of messages, to the platform for remote processing by Prodiguer software agents at IPSL servers in Paris. Such processing takes several forms: Persisting message content to database(s); Launching rollback jobs upon simulation failure; Notifying downstream applications; Automation of visualization pipelines; We will describe and/or demonstrate the platform's: Technical implementation; Inherent ease of scalability; Inherent adaptiveness in respect to supervising simulations; Web portal receiving simulation notifications in realtime.

  13. SONEP: A Software-Defined Optical Network Emulation Platform

    DEFF Research Database (Denmark)

    Azodolmolky, Siamak; Petersen, Martin Nordal; Fagertun, Anna Manolova

    2014-01-01

    Network emulation has been one of the tools of choice for conducting experiments on commodity hardware. In the absence of an easy to use optical network test-bed, researchers can significantly benefit from the availability of a flexible/programmable optical network emulation platform. Exploiting...... the lightweight system virtualization, which is recently supported in modern operating systems, in this work we present the architecture of a Software-Defined Network (SDN) emulation platform for transport optical networks and investigate its usage in a use-case scenario. To the best of our knowledge......, this is for the first time that an SDN-based emulation platform is proposed for modeling and performance evaluation of optical networks. Coupled with recent trend of extension of SDN towards transport (optical) networks, the presented tool can facilitate the evaluation of innovative idea before actual implementations...

  14. A DVE Time Management Simulation and Verification Platform Based on Causality Consistency Middleware

    Science.gov (United States)

    Zhou, Hangjun; Zhang, Wei; Peng, Yuxing; Li, Sikun

    During the course of designing a time management algorithm for DVEs, the researchers always become inefficiency for the distraction from the realization of the trivial and fundamental details of simulation and verification. Therefore, a platform having realized theses details is desirable. However, this has not been achieved in any published work to our knowledge. In this paper, we are the first to design and realize a DVE time management simulation and verification platform providing exactly the same interfaces as those defined by the HLA Interface Specification. Moreover, our platform is based on a new designed causality consistency middleware and might offer the comparison of three kinds of time management services: CO, RO and TSO. The experimental results show that the implementation of the platform only costs small overhead, and that the efficient performance of it is highly effective for the researchers to merely focus on the improvement of designing algorithms.

  15. ADMS Evaluation Platform

    Energy Technology Data Exchange (ETDEWEB)

    2018-01-23

    Deploying an ADMS or looking to optimize its value? NREL offers a low-cost, low-risk evaluation platform for assessing ADMS performance. The National Renewable Energy Laboratory (NREL) has developed a vendor-neutral advanced distribution management system (ADMS) evaluation platform and is expanding its capabilities. The platform uses actual grid-scale hardware, large-scale distribution system models, and advanced visualization to simulate realworld conditions for the most accurate ADMS evaluation and experimentation.

  16. A comparative study of cognitive radio platforms

    CSIR Research Space (South Africa)

    Masonta, MT

    2012-10-01

    Full Text Available -life deployments of CR systems, the research community is now focusing on the development of CR platforms. With different software defined radio (SDR) packages and hardware available, it is confusing to decide which one to build or use. The objective of this paper...

  17. Development and application of knowledge-based subject group integration platforms:A case study of Shanghai Institute of Ceramics,CAS

    Institute of Scientific and Technical Information of China (English)

    Yu; LIU; Jian; FU; Huijun; ZHENG; Hao; CHEN; Zhiping; YANG

    2014-01-01

    Purpose:According to the different requirements of research group users,we established the knowledge-based subject group integration platforms of Shanghai Institute of Ceramics,the Chinese Academy of Sciences(abbreviated as SIC CAS hereinafter),which were designed and constructed to better meet the needs of CAS research groups for their development,collaboration and communication.Design/methodology/approach:We first identified the requirements of users via preliminary investigation,and then chose CASI1 P,iLibrary and XKE technology,respectively as the building tools compatible with the major demands of users.These steps helped us complete the layout design of SIC CAS integration platforms,as well as its knowledge organization and integration.Findings:According to the need of users,we applied three types of platform construction technologies to five SIC integration platforms,and formulated standard norms for the further construction process,which could provide useful reference for a sustainable development for the extensive construction in CAS institutes.Research limitations:In order to make the SIC integration platforms more intelligent and have more functions,we need to enlarge the scale of the Platforms and upgrade the building tools for the platform construction.Practical implications:The nature of SIC sub-project integration platforms is to construct a content-sensitive environment which can embed knowledge services and knowledge applications seamlessly into scientific activities,so the Platform is expected to be a useful tool to help researchers better understand the recent development of the research field and form collaborations with their peers.Originality/value:SIC integration platforms are the only pilot construction that used 3different platform technologies in the first batch of knowledge-based subject group integration platforms of the Chinese Academy of Sciences.The construction is user-centered throughout the whole process,namely,from the technology

  18. Towards an Open Software Platform for Field Robots in Precision Agriculture

    Directory of Open Access Journals (Sweden)

    Kjeld Jensen

    2014-06-01

    Full Text Available Robotics in precision agriculture has the potential to improve competitiveness and increase sustainability compared to current crop production methods and has become an increasingly active area of research. Tractor guidance systems for supervised navigation and implement control have reached the market, and prototypes of field robots performing precision agriculture tasks without human intervention also exist. But research in advanced cognitive perception and behaviour that is required to enable a more efficient, reliable and safe autonomy becomes increasingly demanding due to the growing software complexity. A lack of collaboration between research groups contributes to the problem. Scientific publications describe methods and results from the work, but little field robot software is released and documented for others to use. We hypothesize that a common open software platform tailored to field robots in precision agriculture will significantly decrease development time and resources required to perform experiments due to efficient reuse of existing work across projects and robot platforms. In this work we present the FroboMind software platform and evaluate the performance when applied to precision agriculture tasks.

  19. Quality of SME Business Transfers Matching Platforms: Research Outcomes of 12 European Countries

    NARCIS (Netherlands)

    Oriol Alba; Edwin Weesie; Marie Depelssemaker; Lex van Teeffelen; Nicolas Pirotte

    2016-01-01

    From the preface : The European Commission supports Member States by providing them with recommendations, guidelines, information and good practices. For years, the European Commission has stimulated Member States to develop matching platforms to efficiently support sellers and buyers of SMEs in

  20. Intelligent Tools for Building a Scientific Information Platform

    CERN Document Server

    Skonieczny, Lukasz; Rybiński, Henryk; Niezgodka, Marek

    2012-01-01

    This book is a selection of results obtained within one year of research performed under SYNAT - a nation-wide scientific project aiming to create an infrastructure for scientific content storage and sharing for academia, education and open knowledge society in Poland. The selection refers to the research in artificial intelligence, knowledge discovery and data mining, information retrieval and natural language processing, addressing the problems of implementing intelligent tools for building a scientific information platform. The idea of this book is based on the very successful SYNAT Project Conference and the SYNAT Workshop accompanying the 19th International Symposium on Methodologies for Intelligent Systems (ISMIS 2011). The papers included in this book present an overview and insight into such topics as architecture of scientific information platforms, semantic clustering, ontology-based systems, as well as, multimedia data processing.

  1. IMPROVEMENT OF THE SUPPORTING STRUCTURE OF PLATFORM CAR FOR HIGHER EFFICIENCY OF CONTAINER TRANSPORTATIONS

    Directory of Open Access Journals (Sweden)

    A. O. Lovska

    2017-02-01

    Full Text Available Purpose. The article is aimed to improve supporting structures of the platform car to increase the efficiency of container transportations. Methodology. In order to achieve the objective, the strength investigations of the universal platform car of the model 13-401 were conducted, strength reserves of the supporting elements were defined, and more optimal profiles of basic longitudinal beams of the frame in terms of the minimum material capacity were proposed. Decision correctness was confirmed by the strength calculation of the platform car supporting structure at basic loading operational modes and fatigue taking into account the research database of 107 cycles. It has been proposed to equip a platform car with swing fitting stops for fastening containers on the frame, which allows transportation of 20ft and 40ft containers. In order to improve container transportation efficiency along international transport corridors running through Ukraine, a platform car of articulated type has been designed on the base of the improved platform car structure. The mathematical simulation of dynamic loads of the platform car with containers (two 1CC containers at operational loading modes has been carried out, the maximum accelerations influencing the support structure have been defined, and their multiple values have been considered in computer simulation of the strength of the platform car of articulated type. Findings. The support structure of the platform car of articulated type on the basis of the standard platform car has been developed. Refined values of dynamic loads influencing supporting structure the platform car of articulated type with containers at operational loading modes have been obtained; the maximum equivalent stresses in the platform car support structure have been defined. Originality and practical value. A mathematical model of displacements for a platform car of articulated type with containers at operational loading modes of

  2. The need for a European data platform for hydrological observatories

    Science.gov (United States)

    Blöschl, Günter; Bogena, Heye; Jensen, Karsten; Zacharias, Steffen; Kunstmann, Harald; Heinrich, Ingo; Kunkel, Ralf; Vereecken, Harry

    2017-04-01

    Experimental research in hydrology is amazingly fragmented and disperse. Typically, individual research groups establish and operate their own hydrological test sites and observatories with dedicated funding and specific research questions in mind. Once funding ceases, provisions for archiving and exchanging the data also soon run out and often data are lost or are no longer accessible to the research community. This has not only resulted in missed opportunities for exploring and mining hydrological data but also in a general difficulty in synthesizing research findings from different locations around the world. Many reasons for this fragmentation can be put forward, including the site-specific nature of hydrological processes, the particular types of research funding and the professional education in diverse departments. However, opportunities exist for making hydrological data more accessible and valuable to the research community, for example for designing cross-catchment experiments that build on a common data base and for the development and validation of hydrological models. A number of abundantly instrumented hydrological observatories, including the TERENO catchments in Germany, the HOBE catchment in Denmark and the HOAL catchment in Austria, have, in a first step, started to join forces to serve as a community-driven nucleus for a European data platform of hydrological observatories. The common data platform aims at making data of existing hydrological observatories accessible and available to the research community, thereby providing new opportunities for the design of cross-catchment experiments and model validation efforts. Tangible instruments for implementing this platform include a common data portal, for which the TEODOOR portal (http://www.tereno.net/) is currently used. Intangible instruments include a strong motivational basis. As with any community initiative, it is important to align expectations and to provide incentives to all involved. It is

  3. Research on sudden environmental pollution public service platform construction based on WebGIS

    Science.gov (United States)

    Bi, T. P.; Gao, D. Y.; Zhong, X. Y.

    2016-08-01

    In order to actualize the social sharing and service of the emergency-response information for sudden pollution accidents, the public can share the risk source information service, dangerous goods control technology service and so on, The SQL Server and ArcSDE software are used to establish a spatial database to restore all kinds of information including risk sources, hazardous chemicals and handling methods in case of accidents. Combined with Chinese atmospheric environmental assessment standards, the SCREEN3 atmospheric dispersion model and one-dimensional liquid diffusion model are established to realize the query of related information and the display of the diffusion effect under B/S structure. Based on the WebGIS technology, C#.Net language is used to develop the sudden environmental pollution public service platform. As a result, the public service platform can make risk assessments and provide the best emergency processing services.

  4. NCI's Transdisciplinary High Performance Scientific Data Platform

    Science.gov (United States)

    Evans, Ben; Antony, Joseph; Bastrakova, Irina; Car, Nicholas; Cox, Simon; Druken, Kelsey; Evans, Bradley; Fraser, Ryan; Ip, Alex; Kemp, Carina; King, Edward; Minchin, Stuart; Larraondo, Pablo; Pugh, Tim; Richards, Clare; Santana, Fabiana; Smillie, Jon; Trenham, Claire; Wang, Jingbo; Wyborn, Lesley

    2016-04-01

    The Australian National Computational Infrastructure (NCI) manages Earth Systems data collections sourced from several domains and organisations onto a single High Performance Data (HPD) Node to further Australia's national priority research and innovation agenda. The NCI HPD Node has rapidly established its value, currently managing over 10 PBytes of datasets from collections that span a wide range of disciplines including climate, weather, environment, geoscience, geophysics, water resources and social sciences. Importantly, in order to facilitate broad user uptake, maximise reuse and enable transdisciplinary access through software and standardised interfaces, the datasets, associated information systems and processes have been incorporated into the design and operation of a unified platform that NCI has called, the National Environmental Research Data Interoperability Platform (NERDIP). The key goal of the NERDIP is to regularise data access so that it is easily discoverable, interoperable for different domains and enabled for high performance methods. It adopts and implements international standards and data conventions, and promotes scientific integrity within a high performance computing and data analysis environment. NCI has established a rich and flexible computing environment to access to this data, through the NCI supercomputer; a private cloud that supports both domain focused virtual laboratories and in-common interactive analysis interfaces; as well as remotely through scalable data services. Data collections of this importance must be managed with careful consideration of both their current use and the needs of the end-communities, as well as its future potential use, such as transitioning to more advanced software and improved methods. It is therefore critical that the data platform is both well-managed and trusted for stable production use (including transparency and reproducibility), agile enough to incorporate new technological advances and

  5. Comparison of two lecture delivery platforms in a hybrid distance education program.

    Science.gov (United States)

    Ried, L Douglas; Byers, Katherine

    2009-08-28

    To compare students' preferences for and academic performance using 2 different distance education course content delivery platforms. A randomized, crossover research design was used to compare traditional video with a 4-panel platform among learners on multiple campuses within 1 college of pharmacy.(1) The outcomes were students' preferences for delivery platform and examination scores. Rasch analysis was used to assess unidimensionality and the difficulty of examination items. Hierarchical logistic and multiple regression models were used to assess students' preferences and academic performance. The logistic model predicting preference for the 4-panel or traditional platform was not significant, but African-Americans and Hispanics were more likely to prefer the 4-panel platform than Caucasian and Asian students. The delivery platform did not impact students' academic performance. Students who did well on the semester's previous 2 examinations scored higher on the questions related to schizophrenia. Students with higher Pharmacy College Admission Test (PCAT) scores performed better on the bipolar questions than students who preferred the traditional video platform. The additional faculty time, effort, and cost invested in presenting the class material in a 4-panel platform, and the students' extra time and effort spent viewing the 4-panel platform did not produce a comparable benefit in student preference and performance.

  6. The implementation of Moodle platform through lecturer’s perspectives at English department

    Directory of Open Access Journals (Sweden)

    Tazkiyatunnafs Elhawwa

    2017-09-01

    Full Text Available Information and Communication Technology is now becoming an essential part of everyday life of most people in the world. This paper analysed the main functionalities and tools available in the Moodle platform and their use through lecturer’s perspectives at English Department of IAIN Palangka Raya. This  study belongs to descriptive qualitative research. In the present study, teachers are expected to implement the Moodle platform of Information, Communication and Technology (ICT in EFL classes, and make the Moodle platform of ICT becoming a complement to conventional teaching in EFL classrooms, especially when developing listening, reading and writing skills in English. The results showed that the Moodle platform contains some of the main tools of the standard Moodle platform like assignments, chats, forums, news and quiz/survey. The most the students purposes of the use of the Moodle platform were ‘download materials’, ‘news’ and ‘deliver assignments’, and the most used information materials are ‘texts’ and ‘slides’.

  7. [Establishment pharmacological research platform for "Concurrent treatment of the brain and heart" and its application on dissecting mechanism of Danhong injection].

    Science.gov (United States)

    Zhao, Xiao-Ping; Yu, Yun-Ru; Li, Xue; Shao, Qing; Wang, Yi-Min; Zhao, Tao; Zhao, Chao; Zhao, Bu-Chang; Wang, Yue-Fei; Wang, Yi

    2017-12-01

    The Concurrent treatment of the brain and heart (CTBH) theory is proposed based on traditional Chinese medical theory and clinical practice. In this study, a framework for the pharmacological research platform was established to investigate the principles of concurrent treatment of the brain and heart. The platform for CTBH includes several key techniques for network modeling, discovery of active substances, dissecting mechanism of action and investigation of pharmacokinetic property of TCM. Taking network modeling of CTBH as an example, using database search, literature mining, network construction and module analysis, the that network modules closely associated with the pathological progress of cardiovascular and cerebrovascular diseases were identified, while further functional enrichment analysis of these modules indicated that the key biological processes included oxidative stress, metabolism and inflammation. GSK3B, NOTCH1, CDK4 were identified as key nodes in these network modules. The above-mentioned platform was applied to construct component-biomolecules network of Danhong injection for the identification of common targets and pathways. Among them, GSK3B had the highest correlation with the composition of Danhong injection in the network, and the biological function of whose cluster was related to cell oxidative stress. Based upon results of network analysis, validation experiments suggested that Danhong injection significantly improved the survival rate of oxidative injured myocardial cells and nerve cells, and the protective effect was related to the increase of phosphorylated GSK3β protein expression. Moreover, extracts of Salviae Miltiorrhizae Radix et Rhizoma and Carthami Flos exerted the synergisticcytoprotective effect. The results indicated that the mechanism of treatment of cardiovascular and cerebrovascular diseases of Danhong injection could be studied through network modeling and other methods. In summary, the proposed pharmacological

  8. Data Platforms and Cities

    DEFF Research Database (Denmark)

    Blok, Anders; Courmont, Antoine; Hoyng, Rolien

    2017-01-01

    This section offers a series of joint reflections on (open) data platform from a variety of cases, from cycling, traffic and mapping to activism, environment and data brokering. Data platforms play a key role in contemporary urban governance. Linked to open data initiatives, such platforms are of...

  9. Interdisciplinary Analysis of Drought Communication Through Social Media Platforms and Risk Communication

    Science.gov (United States)

    Wygant, M.

    2015-12-01

    As droughts continue to impact businesses and communities throughout the United States, there needs to be a greater emphasis on drought communication through interdisciplinary approaches, risk communication, and digital platforms. The purpose of this research is to provide an overview of the current literature on communicating drought and suggests areas for further improvement. Specifically, this research focuses on communicating drought through social media platforms such as Facebook, Twitter, and Instagram. It also focuses on the conglomeration of theoretical frameworks within the realm of risk communication, to provide a strong foundation towards future drought communication. This research proposal provides a critical step to advocate for paradigmatic shifts within natural hazard communication.

  10. Mobile Platforms and Development Environments

    CERN Document Server

    Helal, Sumi; Li, Wengdong

    2012-01-01

    Mobile platform development has lately become a technological war zone with extremely dynamic and fluid movement, especially in the smart phone and tablet market space. This Synthesis lecture is a guide to the latest developments of the key mobile platforms that are shaping the mobile platform industry. The book covers the three currently dominant native platforms -- iOS, Android and Windows Phone -- along with the device-agnostic HTML5 mobile web platform. The lecture also covers location-based services (LBS) which can be considered as a platform in its own right. The lecture utilizes a sampl

  11. Development of a platform recommending 3D and spectral digitisation strategies

    Directory of Open Access Journals (Sweden)

    Stefanie Wefers

    2016-11-01

    The aim of the COSCHKR platform is to support cultural heritage experts finding the best suitable recording strategy for their often unique physical cultural heritage object and research question. The platform will support them and will make them aware of the relevant parameters and limitations of the recording strategy with respect to the characteristics of the cultural heritage object, external influences, application, recording devices, and data.

  12. ITS Platform North Denmark

    DEFF Research Database (Denmark)

    Lahrmann, Harry; Agerholm, Niels; Juhl, Jens

    2012-01-01

    This paper presents the project entitled “ITS Platform North Denmark” which is used as a test platform for Intelligent Transportation System (ITS) solutions. The platform consists of a newly developed GNSS/GPRS On Board Unit (OBU) to be installed in 500 cars, a backend server and a specially...

  13. Platform development supportedby gaming

    DEFF Research Database (Denmark)

    Mikkola, Juliana Hsuan; Hansen, Poul H. Kyvsgård

    2007-01-01

    The challenge of implementing industrial platforms in practice can be described as a configuration problem caused by high number of variables, which often have contradictory influences on the total performance of the firm. Consequently, the specific platform decisions become extremely complex......, possibly increasing the strategic risks for the firm. This paper reports preliminary findings on platform management process at LEGO, a Danish toy company.  Specifically, we report the process of applying games combined with simulations and workshops in the platform development. We also propose a framework...

  14. Open-WiSe: A Solar Powered Wireless Sensor Network Platform

    Directory of Open Access Journals (Sweden)

    Arthur Edwards

    2012-06-01

    Full Text Available Because battery-powered nodes are required in wireless sensor networks and energy consumption represents an important design consideration, alternate energy sources are needed to provide more effective and optimal function. The main goal of this work is to present an energy harvesting wireless sensor network platform, the Open Wireless Sensor node (WiSe. The design and implementation of the solar powered wireless platform is described including the hardware architecture, firmware, and a POSIX Real-Time Kernel. A sleep and wake up strategy was implemented to prolong the lifetime of the wireless sensor network. This platform was developed as a tool for researchers investigating Wireless sensor network or system integrators.

  15. Alternative Future Fleet Platform Architecture Study

    Science.gov (United States)

    2016-10-27

    accelerate fielding and the research and development required to develop next-generation capabilities. Adopting this more robust counter- surveillance...produced using steel vessel rules, which reduces resiliency but thus reduces costs. • Common Hull Auxiliary Multi-mission Platform (CHAMP): This...the ship would replace aging mission specific designs with a common hull to stabilize the industrial base, reduce life cycle costs and leverage

  16. How platforms are transforming customer information\\ud management

    OpenAIRE

    Stone, Merlin; Aravopoulou, Eleni; Girardi, Gherardo; Weinzierl, Luisa; Laughlin, Paul; Stott, Ryan; Todeva, Emanuela

    2017-01-01

    Purpose\\ud The purpose of this paper is to explain the development of ecosystems and platforms to manage customer information, and to identify the management, research and teaching implications of this evolution.\\ud \\ud Design/methodology/approach\\ud This article is based on research and industrial experience of two of the co-authors in customer relationshipmanagement, further developed with other co-authors in the field of business models, the research and teaching experience of the universi...

  17. Research on systematization and advancement of shipbuilding production management for flexible and agile response for high value offshore platform

    Directory of Open Access Journals (Sweden)

    Young-Joo Song

    2011-09-01

    In this paper, I'm going to define a standard shipbuilding production management system by investigating the environment of domestic major shipbuilding companies. Also, I'm going to propose a unified ship production management and system for the operation of unified management through detail analysis of the activities and the data flow of ship production management. And, the system functions for the strategic approach of ship production management are investigated through the business administration tools such as performance pyramid, VDT and BSC. Lastly, the research of applying strategic KPI to the digital shipyard as virtual execution platform is conducted.

  18. Hydrodynamic analysis of floating platform for special purposes under complex water environment

    Science.gov (United States)

    Ma, Guang-ying; Yao, Yun-long

    2018-03-01

    This article studied a new floating offshore platform for special purposes, which was assembled by standard floating modules. By using ANSYS AQWA software, the hydrodynamic model of the platform was established. The time history responses of the platform motions and the cable tension forces were calculate under complex water environments, such as wind, wave, current and mooring. The results showed that the tension of the four cables are far less than the breaking tension of the cable, so that the cable will not break. This study can be referenced by the relevant researchers and engineers.

  19. Should biomedical research be like Airbnb?

    Science.gov (United States)

    Bonazzi, Vivien R; Bourne, Philip E

    2017-04-01

    The thesis presented here is that biomedical research is based on the trusted exchange of services. That exchange would be conducted more efficiently if the trusted software platforms to exchange those services, if they exist, were more integrated. While simpler and narrower in scope than the services governing biomedical research, comparison to existing internet-based platforms, like Airbnb, can be informative. We illustrate how the analogy to internet-based platforms works and does not work and introduce The Commons, under active development at the National Institutes of Health (NIH) and elsewhere, as an example of the move towards platforms for research.

  20. Autonomous Landing on Moving Platforms

    KAUST Repository

    Mendoza Chavez, Gilberto

    2016-08-01

    This thesis investigates autonomous landing of a micro air vehicle (MAV) on a nonstationary ground platform. Unmanned aerial vehicles (UAVs) and micro air vehicles (MAVs) are becoming every day more ubiquitous. Nonetheless, many applications still require specialized human pilots or supervisors. Current research is focusing on augmenting the scope of tasks that these vehicles are able to accomplish autonomously. Precise autonomous landing on moving platforms is essential for self-deployment and recovery of MAVs, but it remains a challenging task for both autonomous and piloted vehicles. Model Predictive Control (MPC) is a widely used and effective scheme to control constrained systems. One of its variants, output-feedback tube-based MPC, ensures robust stability for systems with bounded disturbances under system state reconstruction. This thesis proposes a MAV control strategy based on this variant of MPC to perform rapid and precise autonomous landing on moving targets whose nominal (uncommitted) trajectory and velocity are slowly varying. The proposed approach is demonstrated on an experimental setup.

  1. AZTLAN platform: Mexican platform for analysis and design of nuclear reactors

    International Nuclear Information System (INIS)

    Gomez T, A. M.; Puente E, F.; Del Valle G, E.; Francois L, J. L.; Martin del Campo M, C.; Espinosa P, G.

    2014-10-01

    The Aztlan platform Project is a national initiative led by the Instituto Nacional de Investigaciones Nucleares (ININ) which brings together the main public houses of higher studies in Mexico, such as: Instituto Politecnico Nacional, Universidad Nacional Autonoma de Mexico and Universidad Autonoma Metropolitana in an effort to take a significant step toward the calculation autonomy and analysis that seeks to place Mexico in the medium term in a competitive international level on software issues for analysis of nuclear reactors. This project aims to modernize, improve and integrate the neutron, thermal-hydraulic and thermo-mechanical codes, developed in Mexican institutions, within an integrated platform, developed and maintained by Mexican experts to benefit from the same institutions. This project is financed by the mixed fund SENER-CONACYT of Energy Sustain ability, and aims to strengthen substantially to research institutions, such as educational institutions contributing to the formation of highly qualified human resources in the area of analysis and design of nuclear reactors. As innovative part the project includes the creation of a user group, made up of members of the project institutions as well as the Comision Nacional de Seguridad Nuclear y Salvaguardias, Central Nucleoelectrica de Laguna Verde (CNLV), Secretaria de Energia (Mexico) and Karlsruhe Institute of Technology (Germany) among others. This user group will be responsible for using the software and provide feedback to the development equipment in order that progress meets the needs of the regulator and industry; in this case the CNLV. Finally, in order to bridge the gap between similar developments globally, they will make use of the latest super computing technology to speed up calculation times. This work intends to present to national nuclear community the project, so a description of the proposed methodology is given, as well as the goals and objectives to be pursued for the development of the

  2. The transformation of Teacher Work through digital learning platforms

    DEFF Research Database (Denmark)

    Christiansen, René Boyer; Andreasen, Lars Birch

    four transformation tendencies in the educational system regarding teacher work and discuss these in relation to a recent research project which aims at looking at the organizational and didactical implications for teachers working with digital platforms in the Danish primary school.......This paper examines a new mandatory initiative in the Danish primary school regarding digital learning platforms for students, teachers and parents and regards this as a part of a global process that leads to a transformation of teacher work and thus everyday life for teachers in schools. We list...

  3. An Analysis of Business Models in Public Service Platforms

    DEFF Research Database (Denmark)

    Ranerup, Agneta; Zinner Henriksen, Helle; Hedman, Jonas

    2016-01-01

    Public Service Platforms (PSPs) are a new type of technology platform. They are based in the philosophy of New Public Management (NPM) and support public services for citizens in quasi-markets. This article increases our understanding of the business models behind these PSPs in terms of their Value......” that includes dialogues, user evaluations, long-term perspectives on choice, promotion of the ideal of choice, and self-promotion by public agencies. The article contributes to research with its empirical example of the digitalization of NPM and the underlying business logic of PSPs....

  4. The European Platforms on Radiation Protection: a Coordinated Effort to Ensure the Sustainability of the RTD in this Field

    Energy Technology Data Exchange (ETDEWEB)

    Real, A.; Santos, J.; López, M.A.; Montero, M.; Navarro, T.

    2016-07-01

    In the last decade, four platforms on radiation protection issues have been created in Europe: ALLIANCE (radioecology), EURADOS (dosimetry), MELODI (effects of low dose) and NERIS (emergency preparedness and management). The work done in close collaboration within the platforms is contributing to the sustainability of the RTD activities in radiation protection. The platforms have developed Strategic Research Agendas, defining long-term research priorities in their respective disciplines. The ultimate goal is to develop a joint Strategic Research Agenda for radiation protection in Europe.

  5. The European Platforms on Radiation Protection: a Coordinated Effort to Ensure the Sustainability of the RTD in this Field

    International Nuclear Information System (INIS)

    Real, A.; Santos, J.; López, M.A.; Montero, M.; Navarro, T.

    2016-01-01

    In the last decade, four platforms on radiation protection issues have been created in Europe: ALLIANCE (radioecology), EURADOS (dosimetry), MELODI (effects of low dose) and NERIS (emergency preparedness and management). The work done in close collaboration within the platforms is contributing to the sustainability of the RTD activities in radiation protection. The platforms have developed Strategic Research Agendas, defining long-term research priorities in their respective disciplines. The ultimate goal is to develop a joint Strategic Research Agenda for radiation protection in Europe

  6. Addressing service delivery in rural areas through deployment of information and communication technology platforms

    CSIR Research Space (South Africa)

    Foko, Thato E

    2017-05-01

    Full Text Available deployment of ICT Platforms in the rural areas. The contribution of ICT Platform adds to the important notion of access which enhances service delivery. This is seen through the Technology Acceptance Models used in this paper. The main research methodology...

  7. Can Nuclear Installations and Research Centres Adopt Cloud Computing Platform-

    International Nuclear Information System (INIS)

    Pichan, A.; Lazarescu, M.; Soh, S.T.

    2015-01-01

    Cloud Computing is arguably one of the recent and highly significant advances in information technology today. It produces transformative changes in the history of computing and presents many promising technological and economic opportunities. The pay-per-use model, the computing power, abundance of storage, skilled resources, fault tolerance and the economy of scale it offers, provides significant advantages to enterprises to adopt cloud platform for their business needs. However, customers especially those dealing with national security, high end scientific research institutions, critical national infrastructure service providers (like power, water) remain very much reluctant to move their business system to the cloud. One of the main concerns is the question of information security in the cloud and the threat of the unknown. Cloud Service Providers (CSP) indirectly encourages this perception by not letting their customers see what is behind their virtual curtain. Jurisdiction (information assets being stored elsewhere), data duplication, multi-tenancy, virtualisation and decentralized nature of data processing are the default characteristics of cloud computing. Therefore traditional approach of enforcing and implementing security controls remains a big challenge and largely depends upon the service provider. The other biggest challenge and open issue is the ability to perform digital forensic investigations in the cloud in case of security breaches. Traditional approaches to evidence collection and recovery are no longer practical as they rely on unrestricted access to the relevant systems and user data, something that is not available in the cloud model. This continues to fuel high insecurity for the cloud customers. In this paper we analyze the cyber security and digital forensics challenges, issues and opportunities for nuclear facilities to adopt cloud computing. We also discuss the due diligence process and applicable industry best practices which shall be

  8. Envri Cluster - a Community-Driven Platform of European Environmental Researcher Infrastructures for Providing Common E-Solutions for Earth Science

    Science.gov (United States)

    Asmi, A.; Sorvari, S.; Kutsch, W. L.; Laj, P.

    2017-12-01

    European long-term environmental research infrastructures (often referred as ESFRI RIs) are the core facilities for providing services for scientists in their quest for understanding and predicting the complex Earth system and its functioning that requires long-term efforts to identify environmental changes (trends, thresholds and resilience, interactions and feedbacks). Many of the research infrastructures originally have been developed to respond to the needs of their specific research communities, however, it is clear that strong collaboration among research infrastructures is needed to serve the trans-boundary research requires exploring scientific questions at the intersection of different scientific fields, conducting joint research projects and developing concepts, devices, and methods that can be used to integrate knowledge. European Environmental research infrastructures have already been successfully worked together for many years and have established a cluster - ENVRI cluster - for their collaborative work. ENVRI cluster act as a collaborative platform where the RIs can jointly agree on the common solutions for their operations, draft strategies and policies and share best practices and knowledge. Supporting project for the ENVRI cluster, ENVRIplus project, brings together 21 European research infrastructures and infrastructure networks to work on joint technical solutions, data interoperability, access management, training, strategies and dissemination efforts. ENVRI cluster act as one stop shop for multidisciplinary RI users, other collaborative initiatives, projects and programmes and coordinates and implement jointly agreed RI strategies.

  9. Mathematical analysis of the impact mechanism of information platform on agro-product supply chain and agro-product competitiveness

    Directory of Open Access Journals (Sweden)

    Jiang Qi-Jie

    2017-04-01

    Full Text Available How to optimize agro-product supply chain to promote its operating efficiency so as to enhance the competitiveness of regional agricultural products has posed a problem to academic circles, business circles and governments of various levels. One way to solve this problem is to introduce an information platform into the supply chain, which this essay focuses on. Firstly, a review of existing research findings concerning the agro-product competitiveness, agro-product supply chain (ASC and information platform was given. Secondly, we constructed a mathematical model to analyze the impact of information platform on the bullwhip effect in ASC. Thirdly, another mathematical model was constructed to help compare and analyze the impact of information platform on information acquisition of members in ASC. The research results show that the implantation of information platform can mitigate the bullwhip effect in ASC, and members can determine order amount or production more close to the actual market demand. And also the information platform can reduce the time for members in ASC to get information from other members. Besides, information platform can help ASC to alleviate information asymmetry among upstream and downstream members. Furthermore, researches about the operating mechanism and pattern, technical feature and running structure of the information platform, along with their impacts on agro-product supply chain and the competitiveness of agricultural products need to be advanced.

  10. Mathematical analysis of the impact mechanism of information platform on agro-product supply chain and agro-product competitiveness

    Science.gov (United States)

    Jiang, Qi-Jie; Jin, Mao-Zhu; Ren, Pei-Yu

    2017-04-01

    How to optimize agro-product supply chain to promote its operating efficiency so as to enhance the competitiveness of regional agricultural products has posed a problem to academic circles, business circles and governments of various levels. One way to solve this problem is to introduce an information platform into the supply chain, which this essay focuses on. Firstly, a review of existing research findings concerning the agro-product competitiveness, agro-product supply chain (ASC) and information platform was given. Secondly, we constructed a mathematical model to analyze the impact of information platform on the bullwhip effect in ASC. Thirdly, another mathematical model was constructed to help compare and analyze the impact of information platform on information acquisition of members in ASC. The research results show that the implantation of information platform can mitigate the bullwhip effect in ASC, and members can determine order amount or production more close to the actual market demand. And also the information platform can reduce the time for members in ASC to get information from other members. Besides, information platform can help ASC to alleviate information asymmetry among upstream and downstream members. Furthermore, researches about the operating mechanism and pattern, technical feature and running structure of the information platform, along with their impacts on agro-product supply chain and the competitiveness of agricultural products need to be advanced.

  11. Open innovation in health care: analysis of an open health platform.

    Science.gov (United States)

    Bullinger, Angelika C; Rass, Matthias; Adamczyk, Sabrina; Moeslein, Kathrin M; Sohn, Stefan

    2012-05-01

    Today, integration of the public in research and development in health care is seen as essential for the advancement of innovation. This is a paradigmatic shift away from the traditional assumption that solely health care professionals are able to devise, develop, and disseminate novel concepts and solutions in health care. The present study builds on research in the field of open innovation to investigate the adoption of an open health platform by patients, care givers, physicians, family members, and the interested public. Results suggest that open innovation practices in health care lead to interesting innovation outcomes and are well accepted by participants. During the first three months, 803 participants of the open health platform submitted challenges and solutions and intensively communicated by exchanging 1454 personal messages and 366 comments. Analysis of communication content shows that empathic support and exchange of information are important elements of communication on the platform. The study presents first evidence for the suitability of open innovation practices to integrate the general public in health care research in order to foster both innovation outcomes and empathic support. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  12. A Multimodal Deep Log-Based User Experience (UX) Platform for UX Evaluation.

    Science.gov (United States)

    Hussain, Jamil; Khan, Wajahat Ali; Hur, Taeho; Bilal, Hafiz Syed Muhammad; Bang, Jaehun; Hassan, Anees Ul; Afzal, Muhammad; Lee, Sungyoung

    2018-05-18

    The user experience (UX) is an emerging field in user research and design, and the development of UX evaluation methods presents a challenge for both researchers and practitioners. Different UX evaluation methods have been developed to extract accurate UX data. Among UX evaluation methods, the mixed-method approach of triangulation has gained importance. It provides more accurate and precise information about the user while interacting with the product. However, this approach requires skilled UX researchers and developers to integrate multiple devices, synchronize them, analyze the data, and ultimately produce an informed decision. In this paper, a method and system for measuring the overall UX over time using a triangulation method are proposed. The proposed platform incorporates observational and physiological measurements in addition to traditional ones. The platform reduces the subjective bias and validates the user's perceptions, which are measured by different sensors through objectification of the subjective nature of the user in the UX assessment. The platform additionally offers plug-and-play support for different devices and powerful analytics for obtaining insight on the UX in terms of multiple participants.

  13. Platform Expansion Design as Strategic Choice

    DEFF Research Database (Denmark)

    Staykova, Kalina S.; Damsgaard, Jan

    2016-01-01

    In this paper, we address how the strategic choice of platform expansion design impacts the subse-quent platform strategy. We identify two distinct approaches to platform expansion – platform bun-dling and platform constellations, which currently co-exist. The purpose of this paper is to outline...

  14. A Typology of Multi-sided Platforms

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2015-01-01

    In this paper we address how the composition of a platform impacts the platform’s business model. By platform’s business model we mean platform features, platform architecture and platform governance. To this end, we construct the Platform Business Model Framework. We apply the framework to three...

  15. A Versatile Microarray Platform for Capturing Rare Cells

    Science.gov (United States)

    Brinkmann, Falko; Hirtz, Michael; Haller, Anna; Gorges, Tobias M.; Vellekoop, Michael J.; Riethdorf, Sabine; Müller, Volkmar; Pantel, Klaus; Fuchs, Harald

    2015-10-01

    Analyses of rare events occurring at extremely low frequencies in body fluids are still challenging. We established a versatile microarray-based platform able to capture single target cells from large background populations. As use case we chose the challenging application of detecting circulating tumor cells (CTCs) - about one cell in a billion normal blood cells. After incubation with an antibody cocktail, targeted cells are extracted on a microarray in a microfluidic chip. The accessibility of our platform allows for subsequent recovery of targets for further analysis. The microarray facilitates exclusion of false positive capture events by co-localization allowing for detection without fluorescent labelling. Analyzing blood samples from cancer patients with our platform reached and partly outreached gold standard performance, demonstrating feasibility for clinical application. Clinical researchers free choice of antibody cocktail without need for altered chip manufacturing or incubation protocol, allows virtual arbitrary targeting of capture species and therefore wide spread applications in biomedical sciences.

  16. Creating artificial reefs from decommissioned platforms in the North Sea: review of knowledge and proposed programme of research

    Energy Technology Data Exchange (ETDEWEB)

    Aabel, J.P.; Cripps, S.J.; Jensen, A.C.; Picken, G.

    1997-12-31

    This report relates to the case for research and development work on North Sea artificial reefs. There are potentially many benefits that can be derived from platform reefs, for example as an aid to increased fishing yield for commercial fishermen, a means of enhancing fish stocks and protecting habitat for physical damage. In addition there may be a reduction in decommissioning costs for the oil industry and in negative environmental impacts inherent with land-based decommissioning techniques. Negative impacts could be loss of fishing area and changes in the ecosystem. The report will be focused towards practically applicable results that will aid the decision making process. 129 refs., 13 figs., 18 tabs.

  17. Creating artificial reefs from decommissioned platforms in the North Sea: review of knowledge and proposed programme of research

    Energy Technology Data Exchange (ETDEWEB)

    Aabel, J P; Cripps, S J; Jensen, A C; Picken, G

    1998-12-31

    This report relates to the case for research and development work on North Sea artificial reefs. There are potentially many benefits that can be derived from platform reefs, for example as an aid to increased fishing yield for commercial fishermen, a means of enhancing fish stocks and protecting habitat for physical damage. In addition there may be a reduction in decommissioning costs for the oil industry and in negative environmental impacts inherent with land-based decommissioning techniques. Negative impacts could be loss of fishing area and changes in the ecosystem. The report will be focused towards practically applicable results that will aid the decision making process. 129 refs., 13 figs., 18 tabs.

  18. Perfect discipline platform and Promote interactive development

    Directory of Open Access Journals (Sweden)

    Xiang-ming ZENG

    2014-11-01

    Full Text Available Through the questionnaire survey of Marxism’s course construction and Ideological and Political Theory Course in 45 universities, the paper tries to discuss how to enhance the effectiveness of ideological and political theory course by platform of Marxism’s course construction. Research shows that it can enhance the effectiveness of Ideological and Political Theory Course as long as we make full use of platform construction of Marxism’s course, fully display the Marxism’s spirit with the times and the latest achievements in Ideological and political theory course, and Strengthen academic ideological and Political Theory Education. We believe that it can better cultivate socialist builders to achieve the Chinese dream by playing the educational function of Ideological and Political Theory Course.

  19. Development of integrated platform for computational material design

    Energy Technology Data Exchange (ETDEWEB)

    Kiyoshi, Matsubara; Kumi, Itai; Nobutaka, Nishikawa; Akifumi, Kato [Center for Computational Science and Engineering, Fuji Research Institute Corporation (Japan); Hideaki, Koike [Advance Soft Corporation (Japan)

    2003-07-01

    The goal of our project is to design and develop a problem-solving environment (PSE) that will help computational scientists and engineers develop large complicated application software and simulate complex phenomena by using networking and parallel computing. The integrated platform, which is designed for PSE in the Japanese national project of Frontier Simulation Software for Industrial Science, is defined by supporting the entire range of problem solving activity from program formulation and data setup to numerical simulation, data management, and visualization. A special feature of our integrated platform is based on a new architecture called TASK FLOW. It integrates the computational resources such as hardware and software on the network and supports complex and large-scale simulation. This concept is applied to computational material design and the project 'comprehensive research for modeling, analysis, control, and design of large-scale complex system considering properties of human being'. Moreover this system will provide the best solution for developing large and complicated software and simulating complex and large-scaled phenomena in computational science and engineering. A prototype has already been developed and the validation and verification of an integrated platform will be scheduled by using the prototype in 2003. In the validation and verification, fluid-structure coupling analysis system for designing an industrial machine will be developed on the integrated platform. As other examples of validation and verification, integrated platform for quantum chemistry and bio-mechanical system are planned.

  20. Development of integrated platform for computational material design

    International Nuclear Information System (INIS)

    Kiyoshi, Matsubara; Kumi, Itai; Nobutaka, Nishikawa; Akifumi, Kato; Hideaki, Koike

    2003-01-01

    The goal of our project is to design and develop a problem-solving environment (PSE) that will help computational scientists and engineers develop large complicated application software and simulate complex phenomena by using networking and parallel computing. The integrated platform, which is designed for PSE in the Japanese national project of Frontier Simulation Software for Industrial Science, is defined by supporting the entire range of problem solving activity from program formulation and data setup to numerical simulation, data management, and visualization. A special feature of our integrated platform is based on a new architecture called TASK FLOW. It integrates the computational resources such as hardware and software on the network and supports complex and large-scale simulation. This concept is applied to computational material design and the project 'comprehensive research for modeling, analysis, control, and design of large-scale complex system considering properties of human being'. Moreover this system will provide the best solution for developing large and complicated software and simulating complex and large-scaled phenomena in computational science and engineering. A prototype has already been developed and the validation and verification of an integrated platform will be scheduled by using the prototype in 2003. In the validation and verification, fluid-structure coupling analysis system for designing an industrial machine will be developed on the integrated platform. As other examples of validation and verification, integrated platform for quantum chemistry and bio-mechanical system are planned

  1. 3D shape measurement system developed on mobile platform

    Science.gov (United States)

    Wu, Zhoujie; Chang, Meng; Shi, Bowen; Zhang, Qican

    2017-02-01

    Three-dimensional (3-D) shape measurement technology based on structured light has become one hot research field inspired by the increasing requirements. Many methods have been implemented and applied in the industry applications, but most of their equipments are large and complex, cannot be portable. Meanwhile, the popularity of the smart mobile terminals, such as smart phones, provides a platform for the miniaturization and portability of this technology. The measurement system based on phase-shift algorithm and Gray-code pattern under the Android platform on a mobile phone is mainly studied and developed, and it has been encapsulated into a mobile phone application in order to reconstruct 3-D shape data in the employed smart phone easily and quickly. The experimental results of two measured object are given in this paper and demonstrate the application we developed in the mobile platform is effective.

  2. Should biomedical research be like Airbnb?

    Directory of Open Access Journals (Sweden)

    Vivien R Bonazzi

    2017-04-01

    Full Text Available The thesis presented here is that biomedical research is based on the trusted exchange of services. That exchange would be conducted more efficiently if the trusted software platforms to exchange those services, if they exist, were more integrated. While simpler and narrower in scope than the services governing biomedical research, comparison to existing internet-based platforms, like Airbnb, can be informative. We illustrate how the analogy to internet-based platforms works and does not work and introduce The Commons, under active development at the National Institutes of Health (NIH and elsewhere, as an example of the move towards platforms for research.

  3. Zooplankton data collected from zooplankton net casts from RESEARCHER I and other platforms in TOGA Area of Pacific Ocean; 16 March 1968 to 02 July 1970 (NODC Accession 9500141)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Zooplankton species identities and other data were collected using zooplankton casts in the TOGA Area of Pacific Ocean from RESEARCHER I and other platforms. Data...

  4. Towards a Disruptive Digital Platform Model

    DEFF Research Database (Denmark)

    Kazan, Erol

    that digital platforms leverage on three strategic design elements (i.e., business, architecture, and technology design) to create supportive conditions for facilitating disruption. To shed light on disruptive digital platforms, I opted for payment platforms as my empirical context and unit of analysis......Digital platforms are layered modular information technology architectures that support disruption. Digital platforms are particularly disruptive, as they facilitate the quick release of digital innovations that may replace established innovations. Yet, despite their support for disruption, we have...... not fully understood how such digital platforms can be strategically designed and configured to facilitate disruption. To that end, this thesis endeavors to unravel disruptive digital platforms from the supply perspective that are grounded on strategic digital platform design elements. I suggest...

  5. Toward an E-Government Semantic Platform

    Science.gov (United States)

    Sbodio, Marco Luca; Moulin, Claude; Benamou, Norbert; Barthès, Jean-Paul

    This chapter describes the major aspects of an e-government platform in which semantics underpins more traditional technologies in order to enable new capabilities and to overcome technical and cultural challenges. The design and development of such an e-government Semantic Platform has been conducted with the financial support of the European Commission through the Terregov research project: "Impact of e-government on Territorial Government Services" (Terregov 2008). The goal of this platform is to let local government and government agencies offer online access to their services in an interoperable way, and to allow them to participate in orchestrated processes involving services provided by multiple agencies. Implementing a business process through an electronic procedure is indeed a core goal in any networked organization. However, the field of e-government brings specific constraints to the operations allowed in procedures, especially concerning the flow of private citizens' data: because of legal reasons in most countries, such data are allowed to circulate only from agency to agency directly. In order to promote transparency and responsibility in e-government while respecting the specific constraints on data flows, Terregov supports the creation of centrally controlled orchestrated processes; while the cross agencies data flows are centrally managed, data flow directly across agencies.

  6. Groundwater Assessment Platform

    OpenAIRE

    Podgorski, Joel; Berg, Michael

    2018-01-01

    The Groundwater Assessment Platform is a free, interactive online GIS platform for the mapping, sharing and statistical modeling of groundwater quality data. The modeling allows users to take advantage of publicly available global datasets of various environmental parameters to produce prediction maps of their contaminant of interest.

  7. Preparing for a Product Platform

    DEFF Research Database (Denmark)

    Fiil-Nielsen, Ole; Munk, Lone; Mortensen, Niels Henrik

    2005-01-01

    on commonalities and similarities in the product family, and variance should be based on customer demands. To relate these terms and to improve the basis on which decisions are made, we need a way of visualizing the hierarchy of the product family as well as the commonality and variance. This visualization method...... of the platform or ensuring that the platform can meet future demands will be very useful in the preparation process of a platform synthesis as well as in the updating or reengineering of an existing product development platform.......Experience in the industry as well as recent related scientific publications show the benefits of product development platforms. Companies use platforms to develop not a single but multiple products (i.e. a product family) simultaneously. When these product development projects are coordinated...

  8. Coastal Thematic Exploitation Platform (C-TEP): An innovative and collaborative platform to facilitate Big Data coastal research

    Science.gov (United States)

    Tuohy, Eimear; Clerc, Sebastien; Politi, Eirini; Mangin, Antoine; Datcu, Mihai; Vignudelli, Stefano; Illuzzi, Diomede; Craciunescu, Vasile; Aspetsberger, Michael

    2017-04-01

    The Coastal Thematic Exploitation Platform (C-TEP) is an on-going European Space Agency (ESA) funded project to develop a web service dedicated to the observation of the coastal environment and to support coastal management and monitoring. For over 20 years ESA satellites have provided a wealth of environmental data. The availability of an ever increasing volume of environmental data from satellite remote sensing provides a unique opportunity for exploratory science and the development of coastal applications. However, the diversity and complexity of EO data available, the need for efficient data access, information extraction, data management and high spec processing tools pose major challenges to achieving its full potential in terms of Big Data exploitation. C-TEP will provide a new means to handle the technical challenges of the observation of coastal areas and contribute to improved understanding and decision-making with respect to coastal resources and environments. C-TEP will unlock coastal knowledge and innovation as a collaborative, virtual work environment providing access to a comprehensive database of coastal Earth Observation (EO) data, in-situ data, model data and the tools and processors necessary to fully exploit these vast and heterogeneous datasets. The cloud processing capabilities provided, allow users to perform heavy processing tasks through a user-friendly Graphical User Interface (GUI). A connection to the PEPS (Plateforme pour l'Exploitation des Produits Sentinel) archive will provide data from Sentinel missions 1, 2 and 3. Automatic comparison tools will be provided to exploit the in-situ datasets in synergy with EO data. In addition, users may develop, test and share their own advanced algorithms for the extraction of coastal information. Algorithm validation will be facilitated by the capabilities to compute statistics over long time-series. Finally, C-TEP subscription services will allow users to perform automatic monitoring of some key

  9. Simulation research about China Experimental Fast Reactor steam turboset based on Flowmaster platform

    International Nuclear Information System (INIS)

    Yan Hao; Tian Zhaofei

    2014-01-01

    In the third loop of China Experimental Fast Reactor (CEFR), steam turboset take an important role in converting heat energy into electric energy. However, turbo sets have not been operated on the condition of more than 40%P_0 (P_0 is full power) since they were installed. Thus it is necessary to make an analogue simulation. Based on the real models of turbo sets in CEFR, simulation models were created with the help of Flowmaster platform. By using such simulation models, a steady state result in full power circumstance was got, which is in accordance with design parameters. Meanwhile, a transient state simulation with operating condition ranging from full power to 40%P_0 was accomplished and a result which verifies part of performance and running conditions of turbo sets was got. The result of analogue simulation shows that based on Flowmaster platform, the running condition of simulation models can comply with design requirement, and offer reference values to the actual running. Such simulation models can also offer reference values to other simulation models in the third loop of CEFR. (authors)

  10. The Logic of Digital Platform Disruption

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    Digital platforms are disruptive IT artifacts, because they facilitate the quick release of innovative platform derivatives from third parties (e.g., apps). This study endeavours to unravel the disruptive potential, caused by distinct designs and configurations of digital platforms on market...... environments. We postulate that the disruptive potential of digital platforms is determined by the degree of alignment among the business, technology and platform profiles. Furthermore, we argue that the design and configuration of the aforementioned three elements dictates the extent to which open innovation...... is permitted. To shed light on the disruptive potential of digital platforms, we opted for payment platforms as our unit of analysis. Through interviews with experts and payment providers, we seek to gain an in-depth appreciation of how contemporary digital payment platforms are designed and configured...

  11. Ocean Data Interoperability Platform (ODIP): using regional data systems for global ocean research

    Science.gov (United States)

    Schaap, D.; Thijsse, P.; Glaves, H.

    2017-12-01

    Ocean acidification, loss of coral reefs, sustainable exploitation of the marine environment are just a few of the challenges researchers around the world are currently attempting to understand and address. However, studies of these ecosystem level challenges are impossible unless researchers can discover and re-use the large volumes of interoperable multidisciplinary data that are currently only accessible through regional and global data systems that serve discreet, and often discipline specific, user communities. The plethora of marine data systems currently in existence are also using different standards, technologies and best practices making re-use of the data problematic for those engaged in interdisciplinary marine research. The Ocean Data Interoperability Platform (ODIP) is responding to this growing demand for discoverable, accessible and reusable data by establishing the foundations for a common global framework for marine data management. But creation of such an infrastructure is a major undertaking, and one that needs to be achieved in part by establishing different levels of interoperability across existing regional and global marine e-infrastructures. Workshops organised by ODIP II facilitate dialogue between selected regional and global marine data systems in an effort to identify potential solutions that integrate these marine e-infrastructures. The outcomes of these discussions have formed the basis for a number of prototype development tasks that aim to demonstrate effective sharing of data across multiple data systems, and allow users to access data from more than one system through a single access point. The ODIP II project is currently developing four prototype solutions that are establishing interoperability between selected regional marine data management infrastructures in Europe, the USA, Canada and Australia, and with the global POGO, IODE Ocean Data Portal (ODP) and GEOSS systems. The potential impact of implementing these solutions for

  12. E-recruiting Platforms: Features that Influence the Efficiency of Online Recruitment Systems

    Directory of Open Access Journals (Sweden)

    Ondina ROSOIU

    2016-01-01

    Full Text Available Twenty active e-recruitment platform users took part in this study for discovering the most asked for features in a web based hiring process. The respondents were chosen based on their history on such recruitment platforms. With the help of our Internet users we narrowed down the number of platforms, to research for outstanding features and tool efficiency, to five most impressive ones (e-jobs, hipo, bestjobs, LinkedIn, Freelancer. The results were as useful as we expected when we proposed an investigation related to the future of web recruiting platforms. They underlined in a specific manner that most of such web platform users need to have a professional and fully functional environment where they can list their accomplishments and experience and receive direct feedback from employers or employees. The study also shows in detail how much and why do users like to have certain functionalities when they are searching for a new job.

  13. Globus Platform-as-a-Service for Collaborative Science Applications.

    Science.gov (United States)

    Ananthakrishnan, Rachana; Chard, Kyle; Foster, Ian; Tuecke, Steven

    2015-02-01

    Globus, developed as Software-as-a-Service (SaaS) for research data management, also provides APIs that constitute a flexible and powerful Platform-as-a-Service (PaaS) to which developers can outsource data management activities such as transfer and sharing, as well as identity, profile and group management. By providing these frequently important but always challenging capabilities as a service, accessible over the network, Globus PaaS streamlines web application development and makes it easy for individuals, teams, and institutions to create collaborative applications such as science gateways for science communities. We introduce the capabilities of this platform and review representative applications.

  14. OpenML : An R package to connect to the machine learning platform OpenML

    NARCIS (Netherlands)

    Casalicchio, G.; Bossek, J.; Lang, M.; Kirchhoff, D.; Kerschke, P.; Hofner, B.; Seibold, H.; Vanschoren, J.; Bischl, B.

    2017-01-01

    OpenML is an online machine learning platform where researchers can easily share data, machine learning tasks and experiments as well as organize them online to work and collaborate more efficiently. In this paper, we present an R package to interface with the OpenML platform and illustrate its

  15. Transactional Network Platform: Applications

    Energy Technology Data Exchange (ETDEWEB)

    Katipamula, Srinivas; Lutes, Robert G.; Ngo, Hung; Underhill, Ronald M.

    2013-10-31

    In FY13, Pacific Northwest National Laboratory (PNNL) with funding from the Department of Energy’s (DOE’s) Building Technologies Office (BTO) designed, prototyped and tested a transactional network platform to support energy, operational and financial transactions between any networked entities (equipment, organizations, buildings, grid, etc.). Initially, in FY13, the concept demonstrated transactions between packaged rooftop air conditioners and heat pump units (RTUs) and the electric grid using applications or "agents" that reside on the platform, on the equipment, on a local building controller or in the Cloud. The transactional network project is a multi-lab effort with Oakridge National Laboratory (ORNL) and Lawrence Berkeley National Laboratory (LBNL) also contributing to the effort. PNNL coordinated the project and also was responsible for the development of the transactional network (TN) platform and three different applications associated with RTUs. This document describes two applications or "agents" in details, and also summarizes the platform. The TN platform details are described in another companion document.

  16. Wireless Sensor Networks--A Hands-On Modular Experiments Platform for Enhanced Pedagogical Learning

    Science.gov (United States)

    Taslidere, E.; Cohen, F. S.; Reisman, F. K.

    2011-01-01

    This paper presents the use of wireless sensor networks (WSNs) in educational research as a platform for enhanced pedagogical learning. The aim here with the use of a WSN platform was to go beyond the implementation stage to the real-life application stage, i.e., linking the implementation to real-life applications, where abstract theory and…

  17. Vertical Relationships within Platform Marketplaces

    Directory of Open Access Journals (Sweden)

    Mark J. Tremblay

    2016-07-01

    Full Text Available In two-sided markets a platform allows consumers and sellers to interact by creating sub-markets within the platform marketplace. For example, Amazon has sub-markets for all of the different product categories available on its site, and smartphones have sub-markets for different types of applications (gaming apps, weather apps, map apps, ridesharing apps, etc.. The network benefits between consumers and sellers depend on the mode of competition within the sub-markets: more competition between sellers lowers product prices, increases the surplus consumers receive from a sub-market, and makes platform membership more desirable for consumers. However, more competition also lowers profits for a seller which makes platform membership less desirable for a seller and reduces seller entry and the number of sub-markets available on the platform marketplace. This dynamic between seller competition within a sub-market and agents’ network benefits leads to platform pricing strategies, participation decisions by consumers and sellers, and welfare results that depend on the mode of competition. Thus, the sub-market structure is important when investigating platform marketplaces.

  18. Fishpathogens.eu/noda: a free and handy online platform for Betanodavirus targeted research and data sharing.

    Science.gov (United States)

    Mikkelsen, S S; Panzarin, V; Jonstrup, S P; Bigarré, L; Baud, M; Gray, T; Agapow, P-M; Olesen, N J

    2015-08-01

    Viral nervous necrosis (VNN) is a severe neuropathological disease affecting a broad variety of finfish species worldwide. The causative agents of VNN are small viruses with a bi-segmented RNA genome known as betanodaviruses. At least four species with distinct but yet insufficiently characterized epidemiological features are recognized. The spread of VNN to an increasing number of host species, its wide geographic extent and its economical and ecological impacts justify the importance of collating as much molecular data as possible for tracing the origin of viral isolates and highlight the need for a freely accessible tool for epidemiological and molecular data sharing and consultation. For this purpose, we established a web-based specific database using the www.fishpathogens.eu platform, with the aim of collecting molecular and epidemiological information on VNN viruses, with relevance to their control, management and research studies. © 2015 John Wiley & Sons Ltd.

  19. The vacuum platform

    Science.gov (United States)

    McNab, A.

    2017-10-01

    This paper describes GridPP’s Vacuum Platform for managing virtual machines (VMs), which has been used to run production workloads for WLCG and other HEP experiments. The platform provides a uniform interface between VMs and the sites they run at, whether the site is organised as an Infrastructure-as-a-Service cloud system such as OpenStack, or an Infrastructure-as-a-Client system such as Vac. The paper describes our experience in using this platform, in developing and operating VM lifecycle managers Vac and Vcycle, and in interacting with VMs provided by LHCb, ATLAS, ALICE, CMS, and the GridPP DIRAC service to run production workloads.

  20. Bioelectronic platforms for optimal bio-anode of bio-electrochemical systems: From nano- to macro scopes.

    Science.gov (United States)

    Kim, Bongkyu; An, Junyeong; Fapyane, Deby; Chang, In Seop

    2015-11-01

    The current trend of bio-electrochemical systems is to improve strategies related to their applicability and potential for scaling-up. To date, literature has suggested strategies, but the proposal of correlations between each research field remains insufficient. This review paper provides a correlation based on platform techniques, referred to as bio-electronics platforms (BEPs). These BEPs consist of three platforms divided by scope scale: nano-, micro-, and macro-BEPs. In the nano-BEP, several types of electron transfer mechanisms used by electrochemically active bacteria are discussed. In the micro-BEP, factors affecting the formation of conductive biofilms and transport of electrons in the conductive biofilm are investigated. In the macro-BEP, electrodes and separators in bio-anode are debated in terms of real applications, and a scale-up strategy is discussed. Overall, the challenges of each BEP are highlighted, and potential solutions are suggested. In addition, future research directions are provided and research ideas proposed to develop research interest. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. The hackable city : Citymaking in a platform society

    NARCIS (Netherlands)

    de Waal, Martijn; de Lange, Michiel; Bouw, Matthijs

    2017-01-01

    Can computer hacking have positive parallels in the shaping of the built environment? The Hackable City research project was set up with this question in mind, to investigate the potential of digital platforms to open up the citymaking process. Its cofounders Martijn de Waal, Michiel de Lange and

  2. Tectonic resemblance of the Indian Platform, Pakistan with the Moesian Platform, Romania and strategy for exploration of hydrocarbons

    International Nuclear Information System (INIS)

    Memon, A.D.

    1994-01-01

    There is a remarkable tectonic resemblance between the indian Platform (Pakistan) and the Moesian Platform (Romania). As viewed in global tectonic perspective Moeslan and Indian Plates have played important role in Alpine Himalayan Orogeny; Moesian and Indian Platforms are extension of these respective plates. Characteristics features of both the platforms are block faulting which has effected not only the general tectonic framework but has also played important role in oil accumulation. Main producing rocks in the Moesian platform are Jurassic sandstones and cretaceous limestones while in the indian platform cretaceous sandstones are important reservoirs. The average geothermal gradient in the indian platform is 2.45 C/100m with the higher gradients in the central gas producing region. Geothermal gradients in the Moesian platform have an average value of 3 C/100m with higher gradients in the northern in the northern part. Some of the producing structures in both the platforms are remarkably similar, traps associated with normal faults are very important. Extensive exploration carried in the Moesian Platform makes it very important oil producing region of Romania. After the discovery of oil lower Sindh, serious exploration is being carried in the Indian platform. The paper deals with the similarities between these two important platforms. In the light of the studies of the Moesian platform, strategies or exploration of oil and gas in the Indian Platform are suggested. (author)

  3. Utilizing platforms in industrialized construction

    DEFF Research Database (Denmark)

    Bonev, Martin; Wörösch, Michael; Hvam, Lars

    2015-01-01

    platform strategies, this researchhighlights key aspects of adapting platform-based developed theory to industrialised construction.Building projects use different layers of product, process and logistics platforms to form the right cost– value ratio for the target market application, while modelling...

  4. Kajian Teknologi High Altitude Platform (HAP [Study of High Altitude Platform (HAP Technology

    Directory of Open Access Journals (Sweden)

    Amry Daulat Gultom

    2016-07-01

    Full Text Available High Altitude Platform (HAP merupakan solusi alternatif untuk mengatasi keterbatasan infrastruktur terestrial maupun satelit. HAP merupakan pesawat ataupun balon udara yang ditempatkan pada ketinggian 20-50 km di atas permukaan bumi. Kelebihan yang utama dari HAP adalah kemudahan dalam penempatan, fleksibilitas, biaya operasionalnya rendah, delay  propagasi rendah, sudut elevasi lebar, cakupan yang luas. Penelitian ini dilakukan untuk mengetahui potensi HAP untuk komunikasi pita lebar dan perkembangannya di Indonesia. Analisis dilakukan secara deskriptif dengan mengolah data literatur yang didapat. Hasil penelitian menunjukkan bahwa di Indonesia terdapat potensi teknologi HAP untuk komunikasi pita lebar dengan lebar pita 2x300 MHz di band 27,9-28,2 GHz dan 31-31,3 GHz. Namun, belum ada peraturan yang mengatur alokasi frekuensi untuk HAP secara khusus di Indonesia.*****High Altitude Platform (HAP has been developed as an alternative solution in order to overcome limitation of terrestrial and satellite communication system. HAP is an aircraft or balloon situated on 20-50 km above the earth. Main advantages of HAP are flexibility in deployment, low propagation delay, wide elevation angle and broad coverage. The research is conducted to gather HAP potential for broadband communication and its development in Indonesia. Analysis is conducted by descriptive analysis from literature study gather. The research result shows that in Indonesia, there is potential of HAP technology for broadband communication with 2x300 MHz bandwidth within 27,9-28,2 GHz and 31-31,3 GHz. Yet, there are no specific regulations managing frequency allocation for HAP in Indonesia.

  5. Temperature profile data from XBT casts in a World-wide distribution from NOAA Ship RESEARCHER and other platforms from 1982-05-24 to 1996-03-21 (NODC Accession 9600116)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using XBT casts in a World-wide distribution from NOAA Ship RESEARCHER and other platforms from 24 May 1982 to 21 March 1996....

  6. Astrobee: A New Platform for Free-Flying Robotics on the International Space Station

    Science.gov (United States)

    Smith, Trey; Barlow, Jonathan; Bualat, Maria; Fong, Terrence; Provencher, Christopher; Sanchez, Hugo; Smith, Ernest

    2016-01-01

    The Astrobees are next-generation free-flying robots that will operate in the interior of the International Space Station (ISS). Their primary purpose is to provide a flexible platform for research on zero-g freeflying robotics, with the ability to carry a wide variety of future research payloads and guest science software. They will also serve utility functions: as free-flying cameras to record video of astronaut activities, and as mobile sensor platforms to conduct surveys of the ISS. The Astrobee system includes two robots, a docking station, and a ground data system (GDS). It is developed by the Human Exploration Telerobotics 2 (HET-2) Project, which began in Oct. 2014, and will deliver the Astrobees for launch to ISS in 2017. This paper covers selected aspects of the Astrobee design, focusing on capabilities relevant to potential users of the platform.

  7. Node Primitives: an open end-user programming platform for social robots

    OpenAIRE

    Coronado, Enrique; Mastrogiovanni, Fulvio; Venture, Gentiane

    2017-01-01

    With the expected adoption of robots able to seamlessly and intuitively interact with people in real-world scenarios, the need arises to provide non-technically-skilled users with easy-to-understand paradigms for customising robot behaviors. In this paper, we present an interaction design robot programming platform for enabling multidisciplinary social robot research and applications. This platform is referred to Node Primitives (NEP) and consists of two main parts. On the one hand, a ZeroMQ ...

  8. Designing algorithm visualization on mobile platform: The proposed guidelines

    Science.gov (United States)

    Supli, A. A.; Shiratuddin, N.

    2017-09-01

    This paper entails an ongoing study about the design guidelines of algorithm visualization (AV) on mobile platform, helping students learning data structures and algorithm (DSA) subject effectively. Our previous review indicated that design guidelines of AV on mobile platform are still few. Mostly, previous guidelines of AV are developed for AV on desktop and website platform. In fact, mobile learning has been proved to enhance engagement in learning circumstances, and thus effect student's performance. In addition, the researchers highly recommend including UI design and Interactivity in designing effective AV system. However, the discussions of these two aspects in previous AV design guidelines are not comprehensive. The UI design in this paper describes the arrangement of AV features in mobile environment, whereas interactivity is about the active learning strategy features based on learning experiences (how to engage learners). Thus, this study main objective is to propose design guidelines of AV on mobile platform (AVOMP) that entails comprehensively UI design and interactivity aspects. These guidelines are developed through content analysis and comparative analysis from various related studies. These guidelines are useful for AV designers to help them constructing AVOMP for various topics on DSA.

  9. E-recruiting Platforms: Features that Influence the Efficiency of Online Recruitment Systems

    OpenAIRE

    Ondina ROSOIU; Cristian POPESCU

    2016-01-01

    Twenty active e-recruitment platform users took part in this study for discovering the most asked for features in a web based hiring process. The respondents were chosen based on their history on such recruitment platforms. With the help of our Internet users we narrowed down the number of platforms, to research for outstanding features and tool efficiency, to five most impressive ones (e-jobs, hipo, bestjobs, LinkedIn, Freelancer). The results were as useful as we expected when we proposed a...

  10. Designing Polymeric Microfluidic Platforms for Biomedical Applications

    DEFF Research Database (Denmark)

    Vedarethinam, Indumathi

    Micro- and Nanotechnology have the potential to offer a smart solution for diagnostics and academia research with rapid, low cost, robust analysis systems to facilitate biological analyses. New, high throughput microfluidic platforms have the potential to surpass in performance the conventional...... analyses systems in use today. The overall goal of this PhD project is to address two different areas using microfluidics : i) Chromosome analysis by metaphase FISH such a platform, if successful, can immediately substitute the routine, labor-intensive, glass slide-based FISH analyses in Clinical...... Cytogenetics laboratories. During the course of this project, initially the suitability of the polymeric chip substrate was tested and a microfluidic device was developed for performing interphase FISH analysis. With this device, the key factors involved in chromosome spreading crucial to FISH analysis were...

  11. Miniaturized Spacecraft Platform for Command, Data Handling and Electronics, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Microelectronics Research Development Corporation (Micro RDC) proposes to develop a platform of low mass/volume/power, reliable miniaturized electronic modules that...

  12. Adoption of Mobile Payment Platforms

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2016-01-01

    Numerous mobile payment solutions, which rely on new disruptive technologies, have been launched on the payment market in recent years. But despite the growing number of mobile payment apps, very few solutions have turned to be successful as the majority of them fail to gain a critical mass...... of users. In this paper, we investigate successful platform adoption strategies by using the Reach and Range Framework for Multi-Sided Platforms as a strategic tool to which mobile payment providers can adhere in order to tackle some of the main challenges they face throughout the evolution...... of their platforms. The analysis indicates that successful mobile payment solutions tend to be launched as one-sided platforms and then gradually be expanded into being two-sided. Our study showcases that the success of mobile payment platforms lies with the ability of the platform to balance the reach (number...

  13. The Dynamics of Digital Platform Innovation

    DEFF Research Database (Denmark)

    Eaton, Ben

    2016-01-01

    Curated platforms provide an architectural basis for third parties to develop platform complements and for platform owners to control their implementation as a form of open innovation. The refusal to implement complements as innovations can cause tension between platform owners and developers. Th...

  14. PEEX Modelling Platform for Seamless Environmental Prediction

    Science.gov (United States)

    Baklanov, Alexander; Mahura, Alexander; Arnold, Stephen; Makkonen, Risto; Petäjä, Tuukka; Kerminen, Veli-Matti; Lappalainen, Hanna K.; Ezau, Igor; Nuterman, Roman; Zhang, Wen; Penenko, Alexey; Gordov, Evgeny; Zilitinkevich, Sergej; Kulmala, Markku

    2017-04-01

    The Pan-Eurasian EXperiment (PEEX) is a multidisciplinary, multi-scale research programme stared in 2012 and aimed at resolving the major uncertainties in Earth System Science and global sustainability issues concerning the Arctic and boreal Northern Eurasian regions and in China. Such challenges include climate change, air quality, biodiversity loss, chemicalization, food supply, and the use of natural resources by mining, industry, energy production and transport. The research infrastructure introduces the current state of the art modeling platform and observation systems in the Pan-Eurasian region and presents the future baselines for the coherent and coordinated research infrastructures in the PEEX domain. The PEEX modeling Platform is characterized by a complex seamless integrated Earth System Modeling (ESM) approach, in combination with specific models of different processes and elements of the system, acting on different temporal and spatial scales. The ensemble approach is taken to the integration of modeling results from different models, participants and countries. PEEX utilizes the full potential of a hierarchy of models: scenario analysis, inverse modeling, and modeling based on measurement needs and processes. The models are validated and constrained by available in-situ and remote sensing data of various spatial and temporal scales using data assimilation and top-down modeling. The analyses of the anticipated large volumes of data produced by available models and sensors will be supported by a dedicated virtual research environment developed for these purposes.

  15. Resilience of innovation platforms within armed conflicts: the case of ...

    African Journals Online (AJOL)

    . The Sub-Saharan Africa Challenge Program moved into the Province in 2008 and established four innovation platforms (IPs) under Integrated Agricultural Research for Development concepts, in Masisi and Rutshuru districts. The objective of ...

  16. Comparison of Online Survey Recruitment Platforms for Hard-to-Reach Pregnant Smoking Populations: Feasibility Study.

    Science.gov (United States)

    Ibarra, Jose Luis; Agas, Jessica Marie; Lee, Melissa; Pan, Julia Lily; Buttenheim, Alison Meredith

    2018-04-16

    Recruiting hard-to-reach populations for health research is challenging. Web-based platforms offer one way to recruit specific samples for research purposes, but little is known about the feasibility of online recruitment and the representativeness and comparability of samples recruited through different Web-based platforms. The objectives of this study were to determine the feasibility of recruiting a hard-to-reach population (pregnant smokers) using 4 different Web-based platforms and to compare participants recruited through each platform. A screener and survey were distributed online through Qualtrics Panel, Soapbox Sample, Reddit, and Amazon Mechanical Turk (mTurk). Descriptive statistics were used to summarize results of each recruitment platform, including eligibility yield, quality yield, income, race, age, and gestational age. Of the 3847 participants screened for eligibility across all 4 Web-based platforms, 535 were eligible and 308 completed the survey. Amazon mTurk yielded the fewest completed responses (n=9), 100% (9/9) of which passed several quality metrics verifying pregnancy and smoking status. Qualtrics Panel yielded 14 completed responses, 86% (12/14) of which passed the quality screening. Soapbox Sample produced 107 completed surveys, 67% (72/107) of which were found to be quality responses. Advertising through Reddit produced the highest completion rate (n=178), but only 29.2% (52/178) of those surveys passed the quality metrics. We found significant differences in eligibility yield, quality yield, age, number of previous pregnancies, age of smoking initiation, current smokers, race, education, and income (Precruited pregnant smokers, results varied in quality, cost, and percentage of complete responses. Moving forward, investigators should pay careful attention to the percentage yield and cost of online recruitment platforms to maximize internal and external validity. ©Jose Luis Ibarra, Jessica Marie Agas, Melissa Lee, Julia Lily Pan, Alison

  17. Modality comparison for small animal radiotherapy: A simulation study

    Energy Technology Data Exchange (ETDEWEB)

    Bazalova, Magdalena, E-mail: bazalova@stanford.edu; Nelson, Geoff; Noll, John M.; Graves, Edward E. [Department of Radiation Oncology, Molecular Imaging Program at Stanford, Stanford University, Stanford, California 94305 (United States)

    2014-01-15

    Purpose: Small animal radiation therapy has advanced significantly in recent years. Whereas in the past dose was delivered using a single beam and a lead shield for sparing of healthy tissue, conformal doses can be now delivered using more complex dedicated small animal radiotherapy systems with image guidance. The goal of this paper is to investigate dose distributions for three small animal radiation treatment modalities. Methods: This paper presents a comparison of dose distributions generated by the three approaches—a single-field irradiator with a 200 kV beam and no image guidance, a small animal image-guided conformal system based on a modified microCT scanner with a 120 kV beam developed at Stanford University, and a dedicated conformal system, SARRP, using a 220 kV beam developed at Johns Hopkins University. The authors present a comparison of treatment plans for the three modalities using two cases: a mouse with a subcutaneous tumor and a mouse with a spontaneous lung tumor. A 5 Gy target dose was calculated using the EGSnrc Monte Carlo codes. Results: All treatment modalities generated similar dose distributions for the subcutaneous tumor case, with the highest mean dose to the ipsilateral lung and bones in the single-field plan (0.4 and 0.4 Gy) compared to the microCT (0.1 and 0.2 Gy) and SARRP (0.1 and 0.3 Gy) plans. The lung case demonstrated that due to the nine-beam arrangements in the conformal plans, the mean doses to the ipsilateral lung, spinal cord, and bones were significantly lower in the microCT plan (2.0, 0.4, and 1.9 Gy) and the SARRP plan (1.5, 0.5, and 1.8 Gy) than in single-field irradiator plan (4.5, 3.8, and 3.3 Gy). Similarly, the mean doses to the contralateral lung and the heart were lowest in the microCT plan (1.5 and 2.0 Gy), followed by the SARRP plan (1.7 and 2.2 Gy), and they were highest in the single-field plan (2.5 and 2.4 Gy). For both cases, dose uniformity was greatest in the single-field irradiator plan followed by

  18. A LabVIEW® based generic CT scanner control software platform.

    Science.gov (United States)

    Dierick, M; Van Loo, D; Masschaele, B; Boone, M; Van Hoorebeke, L

    2010-01-01

    UGCT, the Centre for X-ray tomography at Ghent University (Belgium) does research on X-ray tomography and its applications. This includes the development and construction of state-of-the-art CT scanners for scientific research. Because these scanners are built for very different purposes they differ considerably in their physical implementations. However, they all share common principle functionality. In this context a generic software platform was developed using LabVIEW® in order to provide the same interface and functionality on all scanners. This article describes the concept and features of this software, and its potential for tomography in a research setting. The core concept is to rigorously separate the abstract operation of a CT scanner from its actual physical configuration. This separation is achieved by implementing a sender-listener architecture. The advantages are that the resulting software platform is generic, scalable, highly efficient, easy to develop and to extend, and that it can be deployed on future scanners with minimal effort.

  19. Improvement in the amine glass platform by bubbling method for a DNA microarray

    Directory of Open Access Journals (Sweden)

    Jee SH

    2015-10-01

    Full Text Available Seung Hyun Jee,1 Jong Won Kim,2 Ji Hyeong Lee,2 Young Soo Yoon11Department of Chemical and Biological Engineering, Gachon University, Seongnam, Gyeonggi, Republic of Korea; 2Genomics Clinical Research Institute, LabGenomics Co., Ltd., Bundang-gu, Seongnam-si, Gyeonggi-do, Republic of KoreaAbstract: A glass platform with high sensitivity for sexually transmitted diseases microarray is described here. An amino-silane-based self-assembled monolayer was coated on the surface of a glass platform using a novel bubbling method. The optimized surface of the glass platform had highly uniform surface modifications using this method, as well as improved hybridization properties with capture probes in the DNA microarray. On the basis of these results, the improved glass platform serves as a highly reliable and optimal material for the DNA microarray. Moreover, in this study, we demonstrated that our glass platform, manufactured by utilizing the bubbling method, had higher uniformity, shorter processing time, lower background signal, and higher spot signal than the platforms manufactured by the general dipping method. The DNA microarray manufactured with a glass platform prepared using bubbling method can be used as a clinical diagnostic tool. Keywords: DNA microarray, glass platform, bubbling method, self-assambled monolayer

  20. Platform decommissioning. Environmental challenges and practical solutions

    International Nuclear Information System (INIS)

    Kvalvik, Inge

    1998-01-01

    The publication gives a short introduction of platform decommissioning, followed by an overview of what to be decommissioned and removed. This will be followed by some of the vital technologies and methods within decommissioning, abandonment of wells, removal and handling of remains that is reuse and scrapping. A final presentation with a view of current research and developments is given. 3 figs

  1. Dental Implant Surrounding Marginal Bone Level Evaluation: Platform Switching versus Platform Matching—One-Year Retrospective Study

    Directory of Open Access Journals (Sweden)

    Eisner Salamanca

    2017-01-01

    Full Text Available The benefits and feasibility of platform switching have been discussed in several studies, reporting lesser crestal bone loss in platform-switched implants than in platform-matched implants. Objective. The aim of the present study was to observe the changes in vertical and horizontal marginal bone levels in platform-switched and platform-matched dental implants. Materials and Methods. 51 patients received 60 dental implants in the present study over a 1-year period. Measurement was performed between the implant shoulder and the most apical and horizontal marginal defect by periapical radiographs to examine the changes of peri-implant alveolar bone before and 12 months after prosthodontic restoration delivery. Results. These marginal bone measurements showed a bone gain of 0.23±0.58 mm in the vertical gap and 0.22±0.53 mm in the horizontal gap of platform matching, while in platform switching a bone gain of 0.93±1 mm (P<0.05 in the vertical gap and 0.50±0.56 mm in the horizontal gap was found. The average vertical gap reduction from the baseline until 12 months was 0.92±1.11 mm in platform switching and 0.29±0.85 mm in platform matching (P<0.05. Conclusions. Within the limitations of the present study, platform switching seemed to be more effective for a better peri-implant alveolar bone vertical and horizontal gap reduction at 1 year.

  2. DEEP SPACE: High Resolution VR Platform for Multi-user Interactive Narratives

    Science.gov (United States)

    Kuka, Daniela; Elias, Oliver; Martins, Ronald; Lindinger, Christopher; Pramböck, Andreas; Jalsovec, Andreas; Maresch, Pascal; Hörtner, Horst; Brandl, Peter

    DEEP SPACE is a large-scale platform for interactive, stereoscopic and high resolution content. The spatial and the system design of DEEP SPACE are facing constraints of CAVETM-like systems in respect to multi-user interactive storytelling. To be used as research platform and as public exhibition space for many people, DEEP SPACE is capable to process interactive, stereoscopic applications on two projection walls with a size of 16 by 9 meters and a resolution of four times 1080p (4K) each. The processed applications are ranging from Virtual Reality (VR)-environments to 3D-movies to computationally intensive 2D-productions. In this paper, we are describing DEEP SPACE as an experimental VR platform for multi-user interactive storytelling. We are focusing on the system design relevant for the platform, including the integration of the Apple iPod Touch technology as VR control, and a special case study that is demonstrating the research efforts in the field of multi-user interactive storytelling. The described case study, entitled "Papyrate's Island", provides a prototypical scenario of how physical drawings may impact on digital narratives. In this special case, DEEP SPACE helps us to explore the hypothesis that drawing, a primordial human creative skill, gives us access to entirely new creative possibilities in the domain of interactive storytelling.

  3. The Educational Platform: Constructing Conceptual Frameworks.

    Science.gov (United States)

    Peca, Kathy; Isham, Mark

    2001-01-01

    The education faculty at Eastern New Mexico University used educational platforms as a means of developing the unit's conceptual framework. Faculty members developed personal platforms, then synthesized them into one curricular area platform. The resultant unit educational platform became the basis for the unit's conceptual framework, which…

  4. Proba-V Mission Exploitation Platform

    Science.gov (United States)

    Goor, Erwin; Dries, Jeroen

    2017-04-01

    VITO and partners developed the Proba-V Mission Exploitation Platform (MEP) as an end-to-end solution to drastically improve the exploitation of the Proba-V (a Copernicus contributing mission) EO-data archive (http://proba-v.vgt.vito.be/), the past mission SPOT-VEGETATION and derived vegetation parameters by researchers, service providers and end-users. The analysis of time series of data (+1PB) is addressed, as well as the large scale on-demand processing of near real-time data on a powerful and scalable processing environment. Furthermore data from the Copernicus Global Land Service is in scope of the platform. From November 2015 an operational Proba-V MEP environment, as an ESA operation service, is gradually deployed at the VITO data center with direct access to the complete data archive. Since autumn 2016 the platform is operational and yet several applications are released to the users, e.g. - A time series viewer, showing the evolution of Proba-V bands and derived vegetation parameters from the Copernicus Global Land Service for any area of interest. - Full-resolution viewing services for the complete data archive. - On-demand processing chains on a powerfull Hadoop/Spark backend e.g. for the calculation of N-daily composites. - Virtual Machines can be provided with access to the data archive and tools to work with this data, e.g. various toolboxes (GDAL, QGIS, GrassGIS, SNAP toolbox, …) and support for R and Python. This allows users to immediately work with the data without having to install tools or download data, but as well to design, debug and test applications on the platform. - A prototype of jupyter Notebooks is available with some examples worked out to show the potential of the data. Today the platform is used by several third party projects to perform R&D activities on the data, and to develop/host data analysis toolboxes. In parallel the platform is further improved and extended. From the MEP PROBA-V, access to Sentinel-2 and landsat data will

  5. Understanding the promises and premises of online health platforms

    Directory of Open Access Journals (Sweden)

    José Van Dijck

    2016-06-01

    Full Text Available This article investigates the claims and complexities involved in the platform-based economics of health and fitness apps. We examine a double-edged logic inscribed in these platforms, promising to offer personal solutions to medical problems while also contributing to the public good. On the one hand, online platforms serve as personalized data-driven services to their customers. On the other hand, they allegedly serve public interests, such as medical research or health education. In doing so, many apps employ a diffuse discourse, hinging on terms like “sharing,” “open,” and “reuse” when they talk about data extraction and distribution. The analytical approach we adopt in this article is situated at the nexus of science and technology studies, political economy, and the sociology of health and illness. The analysis concentrates on two aspects: datafication (the use and reuse of data and commodification (a platform’s deployment of governance and business models. We apply these analytical categories to three specific platforms: 23andMe, PatientsLikeMe, and Parkinson mPower. The last section will connect these individual examples to the wider implications of health apps’ data flows, governance policies, and business models. Regulatory bodies commonly focus on the (medical safety and security of apps, but pay scarce attention to health apps’ techno-economic governance. Who owns user-generated health data and who gets to benefit? We argue that it is important to reflect on the societal implications of health data markets. Governments have the duty to provide conceptual clarity in the grand narrative of transforming health care and health research.

  6. National Community Solar Platform

    Energy Technology Data Exchange (ETDEWEB)

    Rupert, Bart [Clean Energy Collective, Louisville, CO (United States)

    2016-06-30

    This project was created to provide a National Community Solar Platform (NCSP) portal known as Community Solar Hub, that is available to any entity or individual who wants to develop community solar. This has been done by providing a comprehensive portal to make CEC’s solutions, and other proven community solar solutions, externally available for everyone to access – making the process easy through proven platforms to protect subscribers, developers and utilities. The successful completion of this project provides these tools via a web platform and integration APIs, a wide spectrum of community solar projects included in the platform, multiple groups of customers (utilities, EPCs, and advocates) using the platform to develop community solar, and open access to anyone interested in community solar. CEC’s Incubator project includes web-based informational resources, integrated systems for project information and billing systems, and engagement with customers and users by community solar experts. The combined effort externalizes much of Clean Energy Collective’s industry-leading expertise, allowing third parties to develop community solar without duplicating expensive start-up efforts. The availability of this platform creates community solar projects that are cheaper to build and cheaper to participate in, furthering the goals of DOE’s SunShot Initiative. Final SF 425 Final SF 428 Final DOE F 2050.11 Final Report Narrative

  7. Tutoring math platform accessible for visually impaired people.

    Science.gov (United States)

    Maćkowski, Michał Sebastian; Brzoza, Piotr Franciszek; Spinczyk, Dominik Roland

    2018-04-01

    There are many problems with teaching and assessing impaired students in higher education, especially in technical science, where the knowledge is represented mostly by structural information like: math formulae, charts, graphs, etc. Developing e-learning platform for distance education solves this problem only partially due to the lack of accessibility for the blind. The proposed method is based on the decomposition of the typical mathematical exercise into a sequence of elementary sub-exercises. This allows for interactive resolving of math exercises and assessment of the correctness of exercise solutions at every stage. The presented methods were prepared and evaluated by visually impaired people and students. The article presents the accessible interactive tutoring platform for math teaching and assessment, and experience in exploring it. The results of conducted research confirm good understanding of math formulae described according to elaborated rules. Regardless of the level of complexity of the math formulae the level of math formulae understanding is higher for alternative structural description. The proposed solution enables alternative descriptions of math formulae. Based on the research results, the tool for computer-aided interactive learning of mathematics adapted to the needs of the blind has been designed, implemented and deployed as a platform for on-site and online and distance learning. The designed solution can be very helpful in overcoming many barriers that occur while teaching impaired students. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. TurkPrime.com: A versatile crowdsourcing data acquisition platform for the behavioral sciences.

    Science.gov (United States)

    Litman, Leib; Robinson, Jonathan; Abberbock, Tzvi

    2017-04-01

    In recent years, Mechanical Turk (MTurk) has revolutionized social science by providing a way to collect behavioral data with unprecedented speed and efficiency. However, MTurk was not intended to be a research tool, and many common research tasks are difficult and time-consuming to implement as a result. TurkPrime was designed as a research platform that integrates with MTurk and supports tasks that are common to the social and behavioral sciences. Like MTurk, TurkPrime is an Internet-based platform that runs on any browser and does not require any downloads or installation. Tasks that can be implemented with TurkPrime include: excluding participants on the basis of previous participation, longitudinal studies, making changes to a study while it is running, automating the approval process, increasing the speed of data collection, sending bulk e-mails and bonuses, enhancing communication with participants, monitoring dropout and engagement rates, providing enhanced sampling options, and many others. This article describes how TurkPrime saves time and resources, improves data quality, and allows researchers to design and implement studies that were previously very difficult or impossible to carry out on MTurk. TurkPrime is designed as a research tool whose aim is to improve the quality of the crowdsourcing data collection process. Various features have been and continue to be implemented on the basis of feedback from the research community. TurkPrime is a free research platform.

  9. EVALUATION OF FREE PLATFORMS FOR DELIVERY OF MASSIVE OPEN ONLINE COURSES (MOOCS

    Directory of Open Access Journals (Sweden)

    Airton ZANCANARO

    2017-01-01

    Full Text Available For the hosting, management and delivery of Massive Open Online Courses (MOOC it is necessary a technological infrastructure that supports it. Various educational institutions do not have or do not wish to invest in such a structure, possibly because MOOCs are not yet part of official programs of universities, but initiatives by a particular teacher or a research group. Focusing on this problem, this study seeks to identify platforms that make it possible to create, host and provide courses free of charges for the offeror; find in the respective literature, the basic requirements for MOOC platforms and to evaluate the platforms based on the raised requirements. In order to identify the platforms, information was sought in scientific articles and websites dealing with the comparison of platforms and listing the existing MOOC providers. For the definition of evaluation requirements, there was a search in the Web of Science and Scopus databases, looking for the term "Massive Open Online Courses". After applying some filters, 62 works that address platforms and technology were selected for analysis. As a result there is the identification of six platforms that allow the free supply of courses, the proposal for 14 requirements for reviewing them and a frame containing the evaluation of the identified platforms. This assessment is important since it brings knowledge as a basis for selecting a platform that is the most suitable one in terms of the chosen structure and method to store, manage and deliver courses in MOOC format.

  10. A Research on Seamless Platform Change of Reactor Protection System From PLC to FPGA

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Junbeom; Lee, Jonghoon [Konkuk Univ., Seoul (Korea, Republic of); Lee, Jangsoo [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-08-15

    The PLC (Programmable Logic Controller) has been widely used to implement real-time controllers in nuclear RPSs (Reactor Protection Systems). Increasing complexity and maintenance cost, however, are now demanding more powerful and cost-effective implementation such as FPGA (Field-Programmable Gate Array). Abandoning all experience and knowledge accumulated over the decades and starting an all-new development approach is too risky for such safety-critical systems. This paper proposes an RPS software development process with a platform change from PLC to FPGA, while retaining all outputs from the established development. This paper transforms FBD designs of the PLC-based software development into a behaviorally-equivalent Verilog program, which is a starting point of a typical FPGA-based hardware development. We expect that the proposed software development process can bridge the gap between two software developing approaches with different platforms, such as PLC and FPGA. This paper also demonstrates its effectiveness using an example of a prototype version of a real-world RPS in Korea.

  11. A Research on Seamless Platform Change of Reactor Protection System From PLC to FPGA

    International Nuclear Information System (INIS)

    Yoo, Junbeom; Lee, Jonghoon; Lee, Jangsoo

    2013-01-01

    The PLC (Programmable Logic Controller) has been widely used to implement real-time controllers in nuclear RPSs (Reactor Protection Systems). Increasing complexity and maintenance cost, however, are now demanding more powerful and cost-effective implementation such as FPGA (Field-Programmable Gate Array). Abandoning all experience and knowledge accumulated over the decades and starting an all-new development approach is too risky for such safety-critical systems. This paper proposes an RPS software development process with a platform change from PLC to FPGA, while retaining all outputs from the established development. This paper transforms FBD designs of the PLC-based software development into a behaviorally-equivalent Verilog program, which is a starting point of a typical FPGA-based hardware development. We expect that the proposed software development process can bridge the gap between two software developing approaches with different platforms, such as PLC and FPGA. This paper also demonstrates its effectiveness using an example of a prototype version of a real-world RPS in Korea

  12. A RESEARCH ON SEAMLESS PLATFORM CHANGE OF REACTOR PROTECTION SYSTEM FROM PLC TO FPGA

    Directory of Open Access Journals (Sweden)

    JUNBEOM YOO

    2013-08-01

    Full Text Available The PLC (Programmable Logic Controller has been widely used to implement real-time controllers in nuclear RPSs (Reactor Protection Systems. Increasing complexity and maintenance cost, however, are now demanding more powerful and cost-effective implementation such as FPGA (Field-Programmable Gate Array. Abandoning all experience and knowledge accumulated over the decades and starting an all-new development approach is too risky for such safety-critical systems. This paper proposes an RPS software development process with a platform change from PLC to FPGA, while retaining all outputs from the established development. This paper transforms FBD designs of the PLC-based software development into a behaviorally-equivalent Verilog program, which is a starting point of a typical FPGA-based hardware development. We expect that the proposed software development process can bridge the gap between two software developing approaches with different platforms, such as PLC and FPGA. This paper also demonstrates its effectiveness using an example of a prototype version of a real-world RPS in Korea.

  13. A Shared Platform for Studying Second Language Acquisition

    Science.gov (United States)

    MacWhinney, Brian

    2017-01-01

    The study of second language acquisition (SLA) can benefit from the same process of datasharing that has proven effective in areas such as first language acquisition and aphasiology. Researchers can work together to construct a shared platform that combines data from spoken and written corpora, online tutors, and Web-based experimentation. Many of…

  14. Information-computational platform for collaborative multidisciplinary investigations of regional climatic changes and their impacts

    Science.gov (United States)

    Gordov, Evgeny; Lykosov, Vasily; Krupchatnikov, Vladimir; Okladnikov, Igor; Titov, Alexander; Shulgina, Tamara

    2013-04-01

    Analysis of growing volume of related to climate change data from sensors and model outputs requires collaborative multidisciplinary efforts of researchers. To do it timely and in reliable way one needs in modern information-computational infrastructure supporting integrated studies in the field of environmental sciences. Recently developed experimental software and hardware platform Climate (http://climate.scert.ru/) provides required environment for regional climate change related investigations. The platform combines modern web 2.0 approach, GIS-functionality and capabilities to run climate and meteorological models, process large geophysical datasets and support relevant analysis. It also supports joint software development by distributed research groups, and organization of thematic education for students and post-graduate students. In particular, platform software developed includes dedicated modules for numerical processing of regional and global modeling results for consequent analysis and visualization. Also run of integrated into the platform WRF and «Planet Simulator» models, modeling results data preprocessing and visualization is provided. All functions of the platform are accessible by a user through a web-portal using common graphical web-browser in the form of an interactive graphical user interface which provides, particularly, capabilities of selection of geographical region of interest (pan and zoom), data layers manipulation (order, enable/disable, features extraction) and visualization of results. Platform developed provides users with capabilities of heterogeneous geophysical data analysis, including high-resolution data, and discovering of tendencies in climatic and ecosystem changes in the framework of different multidisciplinary researches. Using it even unskilled user without specific knowledge can perform reliable computational processing and visualization of large meteorological, climatic and satellite monitoring datasets through

  15. Analysis of the Motion Control Methods for Stratospheric Balloon-Borne Gondola Platform

    International Nuclear Information System (INIS)

    Wang, H H; Yuan, Z H; Wu, J

    2006-01-01

    At present, gondola platform is one of the stratospheric balloon-borne platforms being in research focus at home and overseas. Comparing to other stratospheric balloon-borne platforms, such as airship platform, gondola platform has advantages of higher stability, rapid in motion regulation and lower energy cost but disadvantages of less supporting capacity and be incapable of fixation. While all platforms have the same goal of keeping them at accurate angle and right pose for the requirements of instruments and objects installed in the platforms, when platforms rotate round the ground level perpendicular. That is accomplishing motion control. But, platform control system has factors of low damper, excessive and uncertain disturbances by the reason of its being hung over balloon in the air, it is hard to achieve the desired control precision because platform is ease to deviate its benchmark motion. Thus, in the controlling procedure in order to get higher precision, it is crucial to perceive the platform's swing synchronously and rapidly, and restrain the influence of disturbances effectively, keep the platform's pose steadily. Furthermore, while the platform in the air regard control center in the ground as reference object, it is ultimate to select a appropriate reference frame and work out the coordinates and implement the adjustment by the PC104 controller. This paper introduces the methods of the motion control based on stratospheric balloon-borne gondola platform. Firstly, this paper compares the characteristic of the flywheel and CMG and specifies the key methods of obtaining two significant states which are 'orientation stability' state and 'orientation tracking' state for platform motion control procedure using CMG as the control actuator. These two states reduce the deviation amplitude of rotation and swing of gondola's motion relative to original motion due to stratospheric intense atmosphere disturbance. We define it as the first procedure. In next

  16. Analysis of the Motion Control Methods for Stratospheric Balloon-Borne Gondola Platform

    Science.gov (United States)

    Wang, H. H.; Yuan, Z. H.; Wu, J.

    2006-10-01

    At present, gondola platform is one of the stratospheric balloon-borne platforms being in research focus at home and overseas. Comparing to other stratospheric balloon-borne platforms, such as airship platform, gondola platform has advantages of higher stability, rapid in motion regulation and lower energy cost but disadvantages of less supporting capacity and be incapable of fixation. While all platforms have the same goal of keeping them at accurate angle and right pose for the requirements of instruments and objects installed in the platforms, when platforms rotate round the ground level perpendicular. That is accomplishing motion control. But, platform control system has factors of low damper, excessive and uncertain disturbances by the reason of its being hung over balloon in the air, it is hard to achieve the desired control precision because platform is ease to deviate its benchmark motion. Thus, in the controlling procedure in order to get higher precision, it is crucial to perceive the platform's swing synchronously and rapidly, and restrain the influence of disturbances effectively, keep the platform's pose steadily. Furthermore, while the platform in the air regard control center in the ground as reference object, it is ultimate to select a appropriate reference frame and work out the coordinates and implement the adjustment by the PC104 controller. This paper introduces the methods of the motion control based on stratospheric balloon-borne gondola platform. Firstly, this paper compares the characteristic of the flywheel and CMG and specifies the key methods of obtaining two significant states which are 'orientation stability' state and 'orientation tracking' state for platform motion control procedure using CMG as the control actuator. These two states reduce the deviation amplitude of rotation and swing of gondola's motion relative to original motion due to stratospheric intense atmosphere disturbance. We define it as the first procedure. In next

  17. Experimental platforms in support of the ASTRID program: existing and planned facilities - 15126

    International Nuclear Information System (INIS)

    Gastaldi, O.; Rodriguez, G.; Ayrault, L.; Collard, B.; Dumesnil, J.; Dujet, F.; Journeau, C.; Latge, C.; Sanseigne, E.; Serre, F.; Tkatschenko, I.; Willermoz, G.

    2015-01-01

    The sodium cooled fast reactors (SFR) French program currently focused on the design of the ASTRID (Advanced Sodium Technological Reactor for Industrial Demonstration) reactor in different fields: energy conversion system, instrumentation for continuous monitoring, In Service Inspection and Repair, core design, fuel handling, thermo hydraulic, severe accidents, large flow electromagnetic pumps... Even if the French experimental prototype implies the development of innovative techniques, concepts and feedback of operations of SFRs are important, the new challenges coming from the objectives to meet GEN-IV requirements need some research and development. To achieve this goal, the generation four French SFR program includes the development of technological platforms with experimental facilities to develop and evaluate innovative options and also qualify some ASTRID specific components. The needs in terms of development, validation and qualification of techniques, components or systems to be used on ASTRID have been reviewed exhaustively in 2014. It allowed to consolidate or to precise the experimental purposes of the four CEA platforms regrouping technological facilities with different strategy of erection. PAPIRUS platform (largely already constructed) is dedicated to in-sodium experimental testing; GISEH platform (also largely already constructed) is devoted to water and air tests in support to hydraulic, thermal-hydraulic and fluid-structure interaction studies; CHEOPS platform (detailed studies and realization contract launched in 2014 aiming at commissioning and start up in 2018) deals with in sodium research and development and some qualifications requiring large scale; and last, PLINIUS-2 platform (commissioning and start up in 2019) concerns prototypic corium behavior studies in severe accident conditions and mitigation device qualification. This paper presents the four platforms and for each of them the experimental needs which are covered by their facilities

  18. Comparison of Comparative Genomic Hybridization Technologies across Microarray Platforms

    Science.gov (United States)

    In the 2007 Association of Biomolecular Resource Facilities (ABRF) Microarray Research Group (MARG) project, we analyzed HL-60 DNA with five platforms: Agilent, Affymetrix 500K, Affymetrix U133 Plus 2.0, Illumina, and RPCI 19K BAC arrays. Copy number variation (CNV) was analyzed ...

  19. Sharing open hardware through ROP, the robotic open platform

    NARCIS (Netherlands)

    Lunenburg, J.; Soetens, R.P.T.; Schoenmakers, F.; Metsemakers, P.M.G.; van de Molengraft, M.J.G.; Steinbuch, M.; Behnke, S.; Veloso, M.; Visser, A.; Xiong, R.

    2014-01-01

    The robot open source software community, in particular ROS, drastically boosted robotics research. However, a centralized place to exchange open hardware designs does not exist. Therefore we launched the Robotic Open Platform (ROP). A place to share and discuss open hardware designs. Among others

  20. Sharing open hardware through ROP, the Robotic Open Platform

    NARCIS (Netherlands)

    Lunenburg, J.J.M.; Soetens, R.P.T.; Schoenmakers, Ferry; Metsemakers, P.M.G.; Molengraft, van de M.J.G.; Steinbuch, M.

    2013-01-01

    The robot open source software community, in particular ROS, drastically boosted robotics research. However, a centralized place to exchange open hardware designs does not exist. Therefore we launched the Robotic Open Platform (ROP). A place to share and discuss open hardware designs. Among others

  1. Complex products and Systems: Potential from using layout platforms

    NARCIS (Netherlands)

    Hofer, A.P.; Halman, J.I.M.

    2004-01-01

    In their quest to manage the complexity of offering greater product variety, firms in many industries are considering platform-based development of product families. Key in this approach is the sharing of components, modules, and other assets across a family of products. Current research indicates

  2. Research on distributed heterogeneous data PCA algorithm based on cloud platform

    Science.gov (United States)

    Zhang, Jin; Huang, Gang

    2018-05-01

    Principal component analysis (PCA) of heterogeneous data sets can solve the problem that centralized data scalability is limited. In order to reduce the generation of intermediate data and error components of distributed heterogeneous data sets, a principal component analysis algorithm based on heterogeneous data sets under cloud platform is proposed. The algorithm performs eigenvalue processing by using Householder tridiagonalization and QR factorization to calculate the error component of the heterogeneous database associated with the public key to obtain the intermediate data set and the lost information. Experiments on distributed DBM heterogeneous datasets show that the model method has the feasibility and reliability in terms of execution time and accuracy.

  3. REVEAL: Software Documentation and Platform Migration

    Science.gov (United States)

    Wilson, Michael A.; Veibell, Victoir T.; Freudinger, Lawrence C.

    2008-01-01

    The Research Environment for Vehicle Embedded Analysis on Linux (REVEAL) is reconfigurable data acquisition software designed for network-distributed test and measurement applications. In development since 2001, it has been successfully demonstrated in support of a number of actual missions within NASA s Suborbital Science Program. Improvements to software configuration control were needed to properly support both an ongoing transition to operational status and continued evolution of REVEAL capabilities. For this reason the project described in this report targets REVEAL software source documentation and deployment of the software on a small set of hardware platforms different from what is currently used in the baseline system implementation. This report specifically describes the actions taken over a ten week period by two undergraduate student interns and serves as a final report for that internship. The topics discussed include: the documentation of REVEAL source code; the migration of REVEAL to other platforms; and an end-to-end field test that successfully validates the efforts.

  4. OnCampus: a mobile platform towards a smart campus.

    Science.gov (United States)

    Dong, Xin; Kong, Xiangjie; Zhang, Fulin; Chen, Zhen; Kang, Jialiang

    2016-01-01

    An increasing number of researchers and practitioners are working to develop smart cities. Considerable attention has been paid to the college campus as it is an important component of smart cities. Consequently, the question of how to construct a smart campus has become a topical one. Here, we propose a scheme that can facilitate the construction of a smart and friendly campus. We primarily focus on three aspects of smart campuses. These are: the formation of social circles based on interests mining, the provision of educational guidance based on emotion analysis of information posted on a platform, and development of a secondary trading platform aimed at optimizing the allocation of campus resources. Based on these objectives, we designed and implemented a mobile platform called OnCampus as the first step towards the development of a smart campus that has been introduced in some colleges. We found that OnCampus could successfully accomplish the three above mentioned functions of a smart campus.

  5. Product Platform Screening at LEGO

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Steen Jensen, Thomas; Nielsen, Ole Fiil

    2012-01-01

    Product platforms offer great benefits to companies developing new products in highly competitive markets. Literature describes how a single platform can be designed from a technical point of view, but rarely mentions how the process begins. How do companies identify possible platform candidates...... after a few changes had been applied to the initial process layout. This case study shows how companies must focus on a limited selection of simultaneous projects in order to keep focus. Primary stakeholders must be involved from the very beginning, and short presentations of the platform concepts...

  6. Advancing Microgrid Research at NREL

    Energy Technology Data Exchange (ETDEWEB)

    2018-04-25

    NREL expanded its microgrid research capabilities at the Energy System Integration Facility (ESIF) with the purchase of a Schweitzer Engineering Laboratories (SEL) microgrid controller, resulting in a more comprehensive microgrid research platform. NREL's microgrid research platform allows manufacturers, utilities, and integrators to develop and evaluate their technology or configuration at full power before implementation - something only possible at a handful of facilities in the world.

  7. New Modeling and Simulation Platform for Communications Systems:(I Double Sideband Suppressed Carrier AM Modulator DSB-SC

    Directory of Open Access Journals (Sweden)

    H. A. Ahmed

    2012-08-01

    Full Text Available The main goal of this paper is to introduce a new platform for the implementation and simulation of communication systems. SCILAB/SCICOS is an open source software for conducting communication system related experiments, aiming to provide an experimentation platform for research on communication theories. Double Sideband Suppressed Carrier (DSB-SC Modulator is modeled and simulated using this platform.

  8. Reusable platform concepts

    International Nuclear Information System (INIS)

    Gudmestad, O.T.; Sparby, B.K.; Stead, B.L.

    1993-01-01

    There is an increasing need to reduce costs of offshore production facilities in order to make development of offshore fields profitable. For small fields with short production time there is in particular a need to investigate ways to reduce costs. The idea of platform reuse is for such fields particularly attractive. This paper will review reusable platform concepts and will discuss their range of application. Particular emphasis will be placed on technical limitations. Traditional concepts as jackups and floating production facilities will be discussed by major attention will be given to newly developed ideas for reuse of steel jackets and concrete structures. It will be shown how the operator for several fields can obtain considerable savings by applying such reusable platform concepts

  9. KubeNow: an On-Demand Cloud-Agnostic Platform for Microservices-Based Research Environments

    OpenAIRE

    Capuccini, Marco; Larsson, Anders; Carone, Matteo; Novella, Jon Ander; Sadawi, Noureddin; Gao, Jianliang; Toor, Salman; Spjuth, Ola

    2018-01-01

    Microservices platforms, such as Kubernetes, have received a great deal of attention lately as they offer elastic and resilient orchestration for services implemented as portable, light-weight, software containers. While current solutions for cloud-based Kubernetes deployments are mainly focusing on maintaining long-running infrastructure, aimed to sustain highly-available services, the scientific community is embracing software containers for more demanding data analysis. To this extent, the...

  10. Exploration and implementation of ontology-based cultural relic knowledge map integration platform

    Science.gov (United States)

    Yang, Weiqiang; Dong, Yiqiang

    2018-05-01

    To help designers to better carry out creative design and improve the ability of searching traditional cultural relic information, the ontology-based knowledge map construction method was explored and an integrated platform for cultural relic knowledge map was developed. First of all, the construction method of the ontology of cultural relics was put forward, and the construction of the knowledge map of cultural relics was completed based on the constructed cultural relic otology. Then, a personalized semantic retrieval framework for creative design was proposed. Finally, the integrated platform of the knowledge map of cultural relics was designed and realized. The platform was divided into two parts. One was the foreground display system, which was used for designers to search and browse cultural relics. The other was the background management system, which was for cultural experts to manage cultural relics' knowledge. The research results showed that the platform designed could improve the retrieval ability of cultural relic information. To sum up, the platform can provide a good support for the designer's creative design.

  11. Platform development: implications for portfolio management

    DEFF Research Database (Denmark)

    Hsuan, Juliana; Hansen, Poul H. Kyvsgård

    2007-01-01

    " The challenge of implementing industrial platforms in practice can be described as a configuration problem caused by a considerable number of variables, which often have contradictory influences on the total performance of the firm. Consequently, the specific platform decisions become extremely...... complex, possibly increasing the strategic risks for the firm. This paper reports preliminary findings on platform management process at LEGO, a Danish toy company. Specifically, we report the process of applying games combined with simulations and workshops in the platform development. We also propose...... a framework, based on the portfolio management thinking to evaluate the degree of modularity embedded in a given platform and to which extent it is aligned with other platforms."...

  12. Stratifying the Develoment of Product Platforms

    DEFF Research Database (Denmark)

    Sköld, Martin; Karlsson, Christer

    2013-01-01

    companies develop platforms for different aims, purposes, and product scopes. Following on from this, the requirements for platform development resources, the ways of organizing platform development, and the implications for management styles have not been explored and are presumably varying. To start...... influencing the project length, requirements for platform development resources, principles for organizing, and implications for management styles....

  13. Real-time multi-parameter cell-based analysis platform

    DEFF Research Database (Denmark)

    Caviglia, Claudia

    biomedical diagnostic techniques, drug discovery and screening. My project focused on the further development, improvement and exploration of the EXCELL microfluidic platform with particular interest in drug kinetic monitoring and neurotransmitter detection. The aim was to perform multi-parameter real...... of protocols and procedures for performing different cellular assays. (2) Electrochemical impedance spectroscopy (EIS) applied for drug screening and drug delivery in cancer research and wound healing studies. (3) Amperometry for monitoring of neurotransmitter exocytosis, relevant in research on Parkinson...

  14. A CLOUD-BASED PLATFORM SUPPORTING GEOSPATIAL COLLABORATION FOR GIS EDUCATION

    Directory of Open Access Journals (Sweden)

    X. Cheng

    2015-05-01

    Full Text Available GIS-related education needs support of geo-data and geospatial software. Although there are large amount of geographic information resources distributed on the web, the discovery, process and integration of these resources are still unsolved. Researchers and teachers always searched geo-data by common search engines but results were not satisfied. They also spent much money and energy on purchase and maintenance of various kinds of geospatial software. Aimed at these problems, a cloud-based geospatial collaboration platform called GeoSquare was designed and implemented. The platform serves as a geoportal encouraging geospatial data, information, and knowledge sharing through highly interactive and expressive graphic interfaces. Researchers and teachers can solve their problems effectively in this one-stop solution. Functions, specific design and implementation details are presented in this paper. Site of GeoSquare is: http://geosquare.tianditu.com/

  15. a Cloud-Based Platform Supporting Geospatial Collaboration for GIS Education

    Science.gov (United States)

    Cheng, X.; Gui, Z.; Hu, K.; Gao, S.; Shen, P.; Wu, H.

    2015-05-01

    GIS-related education needs support of geo-data and geospatial software. Although there are large amount of geographic information resources distributed on the web, the discovery, process and integration of these resources are still unsolved. Researchers and teachers always searched geo-data by common search engines but results were not satisfied. They also spent much money and energy on purchase and maintenance of various kinds of geospatial software. Aimed at these problems, a cloud-based geospatial collaboration platform called GeoSquare was designed and implemented. The platform serves as a geoportal encouraging geospatial data, information, and knowledge sharing through highly interactive and expressive graphic interfaces. Researchers and teachers can solve their problems effectively in this one-stop solution. Functions, specific design and implementation details are presented in this paper. Site of GeoSquare is: http://geosquare.tianditu.com/

  16. Turbine engine airfoil and platform assembly

    Science.gov (United States)

    Campbell, Christian X [Oviedo, FL; James, Allister W [Chuluota, FL; Morrison, Jay A [Oviedo, FL

    2012-07-31

    A turbine airfoil (22A) is formed by a first process using a first material. A platform (30A) is formed by a second process using a second material that may be different from the first material. The platform (30A) is assembled around a shank (23A) of the airfoil. One or more pins (36A) extend from the platform into holes (28) in the shank (23A). The platform may be formed in two portions (32A, 34A) and placed around the shank, enclosing it. The two platform portions may be bonded to each other. Alternately, the platform (30B) may be cast around the shank (23B) using a metal alloy with better castability than that of the blade and shank, which may be specialized for thermal tolerance. The pins (36A-36D) or holes for them do not extend to an outer surface (31) of the platform, avoiding stress concentrations.

  17. The Innovative Capabilities Of Digital Payment Platforms

    DEFF Research Database (Denmark)

    Kazan, Erol

    2015-01-01

    This study presents a model for studying the innovative capabilities of digital payment platforms in regards to open innovation integration and commercialization. We perceive digital platforms as layered modular IT artifacts, where platform governance and the configuration of platform layers impact...... the support for open innovation. The proposed model has been employed in a comparative case study between two digital payment platforms: Apple Pay and Google Wallet. The findings suggest that digital payment platforms make use of boundary resources to be highly integrative or integratable, which supports...... the intended conjoint commercialization efforts. Furthermore, the architectural design of digital platforms impacts the access to commercialization, resulting to an exclusion or inclusion strategy in accessing value opportunities. Our findings contribute to the open innovation and digital platform literature...

  18. EPCAL: ETS Platform for Collaborative Assessment and Learning. Research Report. ETS RR-17-49

    Science.gov (United States)

    Hao, Jiangang; Liu, Lei; von Davier, Alina A.; Lederer, Nathan; Zapata-Rivera, Diego; Jaki, Peter; Bakkenson, Michael

    2017-01-01

    Most existing software tools for online collaboration are designed to support the collaboration itself instead of the study of collaboration with a systematic team and task management system. In this report, we identify six important features for a platform to facilitate the study of online collaboration. We then introduce the Educational Testing…

  19. A supply sided analysis of leading MOOC platforms and universities

    Directory of Open Access Journals (Sweden)

    Georg Peters

    2016-03-01

    Full Text Available Investing in education is generally considered as a promising strategy to fight poverty and increase prosperity. This applies to all levels of an economy reaching from individuals to local communities and countries and has a global perspective as well. However, high-quality education is often costly and not available anytime anywhere. Therefore, any promising concept that might help to democratize education is worth pursuing, in a sense that it makes education accessible for everybody without any restrictions. The characteristics attributed to MOOC – Massive Open Online Courses are promising to contribute to this objective. Hence, our objective is to analyse MOOC as it currently operates. Obviously, there is a huge demand for free high-quality education anytime anywhere but a shortage on the supply side. So, we will concentrate on supply-sided effects and study MOOC platforms as well as content providers, particularly universities. We focus our research on some of the leading platforms and universities worldwide. Relative to their size Australia and the Netherlands are very active players in the MOOC sector. Germany is lagging behind and leading universities in the UK seem to virtually refrain from offering MOOC. Our research also shows the leading role of US universities and platform providers.

  20. PR-PR: cross-platform laboratory automation system.

    Science.gov (United States)

    Linshiz, Gregory; Stawski, Nina; Goyal, Garima; Bi, Changhao; Poust, Sean; Sharma, Monica; Mutalik, Vivek; Keasling, Jay D; Hillson, Nathan J

    2014-08-15

    To enable protocol standardization, sharing, and efficient implementation across laboratory automation platforms, we have further developed the PR-PR open-source high-level biology-friendly robot programming language as a cross-platform laboratory automation system. Beyond liquid-handling robotics, PR-PR now supports microfluidic and microscopy platforms, as well as protocol translation into human languages, such as English. While the same set of basic PR-PR commands and features are available for each supported platform, the underlying optimization and translation modules vary from platform to platform. Here, we describe these further developments to PR-PR, and demonstrate the experimental implementation and validation of PR-PR protocols for combinatorial modified Golden Gate DNA assembly across liquid-handling robotic, microfluidic, and manual platforms. To further test PR-PR cross-platform performance, we then implement and assess PR-PR protocols for Kunkel DNA mutagenesis and hierarchical Gibson DNA assembly for microfluidic and manual platforms.

  1. Performance Measurement of Complex Event Platforms

    Directory of Open Access Journals (Sweden)

    Eva Zámečníková

    2016-12-01

    Full Text Available The aim of this paper is to find and compare existing solutions of complex event processing platforms (CEP. CEP platforms generally serve for processing and/or predicting of high frequency data. We intend to use CEP platform for processing of complex time series and integrate a solution for newly proposed method of decision making. The decision making process will be described by formal grammar. As there are lots of CEP solutions we will take the following characteristics under consideration - the processing in real time, possibility of processing of high volume data from multiple sources, platform independence, platform allowing integration with user solution and open license. At first we will talk about existing CEP tools and their specific way of use in praxis. Then we will mention the design of method for formalization of business rules used for decision making. Afterwards, we focus on two platforms which seem to be the best fit for integration of our solution and we will list the main pros and cons of each approach. Next part is devoted to benchmark platforms for CEP. Final part is devoted to experimental measurements of platform with integrated method for decision support.

  2. Sociomaterial Practices: Challenges in Developing a Virtual Business Community Platform in Agriculture

    Directory of Open Access Journals (Sweden)

    Norberto Hoppen

    2017-07-01

    Full Text Available Virtual business communities (VBC are virtual networks of people who share common interests and comprise online software platforms that enables the fast exchange of information, collaboration and business interactions. From 2011 to 2015, we developed a design science research to create a VBC platform for an agricultural cluster of flower growers in the South of Brazil. The goal of this platform was to help to structure and strengthen this cluster by bringing together buyers and sellers while fostering cooperation to boost cluster competitiveness and economic development in the region. However, a number of challenges surfaced during the process, which led to a failure in the VBC platform’s diffusion. We adopted a sociomaterial perspective based on the mangle of practice concept (Pickering, 1993 to investigate this failure, by analyzing the key challenges involved in developing a VBC platform in an agricultural context. As its main result, this paper reveals the mangling process during the design and application of the VBC platform and details the different instances of tuning between the participants and the technology. We observed resistance and factors that weakened cooperation and resulted in a lack of governance rules, which are key to the success of a VBC platform.

  3. Digital training platform for interpreting radiographic images of the chest.

    Science.gov (United States)

    McLaughlin, L; Woznitza, N; Cairns, A; McFadden, S L; Bond, R; Hughes, C M; Elsayed, A; Finlay, D; McConnell, J

    2018-05-01

    Time delays and errors exist which lead to delays in patient care and misdiagnosis. Reporting clinicians follow guidance to form their own search strategy. However, little research has tested these training guides. With the use of eye tracking technology and expert input we developed a digital training platform to be used in chest image interpretation learning. Two sections of a digital training platform were planned and developed; A) a search strategy training tool to assist reporters during their interpretation of images, and B) an educational tool to communicate the search strategies of expert viewers to trainees by using eye tracking technology. A digital training platform for use in chest image interpretation was created based on evidence within the literature, expert input and two search strategies previously used in clinical practice. Images and diagrams, aiding translation of the platform content, were incorporated where possible. The platform is structured to allow the chest image interpretation process to be clear, concise and methodical. A search strategy was incorporated within the tool to investigate its use, with the possibility that it could be recommended as an evidence based approach for use by reporting clinicians. Eye tracking, a checklist and voice recordings have been combined to form a multi-dimensional learning tool, which has never been used in chest image interpretation learning before. The training platform for use in chest image interpretation learning has been designed, created and digitised. Future work will establish the efficacy of the developed approaches. Crown Copyright © 2018. Published by Elsevier Ltd. All rights reserved.

  4. Mission Specific Platforms: Past achievements and future developments in European led ocean research drilling.

    Science.gov (United States)

    Cotterill, Carol; McInroy, David; Stevenson, Alan

    2013-04-01

    Mission Specific Platform (MSP) expeditions are operated by the European Consortium for Ocean Research Drilling (ECORD). Each MSP expedition is unique within the Integrated Ocean Drilling Program (IODP). In order to complement the abilities of the JOIDES Resolution and the Chikyu, the ECORD Science Operator (ESO) must source vessels and technology suitable for each MSP proposal on a case-by-case basis. The result is that ESO can meet scientific requirements in a flexible manner, whilst maintaining the measurements required for the IODP legacy programme. The process of tendering within EU journals for vessels and technology means that the planning process for each MSP Expedition starts many years in advance of the operational phase. Involvement of proposal proponents from this early stage often leads to the recognition for technological research and development to best meet the scientific aims and objectives. One example of this is the planning for the Atlantis Massif proposal, with collaborative development between the British Geological Survey (BGS) and MARUM, University of Bremen, on suitable instruments for seabed drills, with the European Petrophysics Consortium (EPC) driving the development of suitable wireline logging tools that can be used in association with such seabed systems. Other technological developments being undertaken within the European IODP community include in-situ pressure sampling for gas hydrate expeditions, deep biosphere and fluid sampling equipment and CORK technology. This multi-national collaborative approach is also employed by ESO in the operational phase. IODP Expedition 302 ACEX saw vessel and ice management support from Russia and Sweden to facilitate the first drilling undertaken in Arctic sea ice. A review of MSP expeditions past, present and future reveal the significant impact of European led operations and scientific research within the current IODP programme, and also looking forward to the start of the new International

  5. Experimental Platform for Usability Testing of Secure Medical Sensor Network Protocols

    DEFF Research Database (Denmark)

    Andersen, Jacob; Lo, Benny P.; Yang, Guang-Zhong

    2008-01-01

    designed security mechanisms are essential. Several experimental sensor network platforms have emerged in recent years targeted for clinical use. However, few of them consider the importance of security issues such as privacy and access control, and how these can impact the usability of the platform, while......Implementing security mechanisms such as access control for clinical use is a challenging research issue in BSN due to its required heterogeneous operating responses ranging from chronic diseases management to emergency care. To ensure the clinical uptake of the BSN technology, appropriately...... others develop BSN security without considering how a prototype implementation would be received by clinicians in real-life situations. The purpose of this paper is to present our initial effort in building a flexible experimental platform for providing a basic infrastructure with symmetric AES...

  6. Cretaceous tropical carbonate platform changes used as paleoclimatic and paleoceanic indicators: the three lower Cretaceous platform crises

    Science.gov (United States)

    Arnaud-Vanneau, A.; Vrielynck, B.

    2009-04-01

    Carbonate platform sediments are of biogenic origin. More commonly the bioclasts are fragments of shells and skeletons. The bioclastic composition of a limestone may reflect the nature of biota inhabiting the area and a carbonate platform can be estimated as a living factory, which reflects the prevailing ecological factors. The rate of carbonate production is highest in the tropics, in oligotrophic environments, and in the photic zone. The rate of carbonate production varies greatly with temperature and nutrient input. Three types of biotic carbonate platform can be distinguished. The highest carbonate production is linked to oligotrophic carbonate platform characterized by the presence of assemblages with hermatypic corals. This type of platform is developed in shallow marine environment, nutrient poor water and warm tropical sea. A less efficient production of carbonate platform is related to mesotrophic environments in cooler and/or deeper water and associated to nutrient flux with, sometime, detrital input. The biota includes red algae, solitary coral and branching ahermatypic corals, common bryozoans, crinoids and echinoids. The less productive carbonate platform is the eutrophic muddy platform where the mud is due to the intense bacterial activity, probably related to strong nutrient flux. All changes of type of carbonate platform can be related to climatic and oceanic changes. Three platform crises occurred during lower Cretaceous time. They are followed by important turnover of microfauna (large benthic foraminifers) and microflora (marine algae). They start with the demise of the previous oligotrophic platform, they continue with oceanic perturbations, expression of which was the widespread deposition of organic-rich sediments, well expressed during Late Aptian/Albian and Cenomanian Turonian boundary and the replacement of previous oligotrophic platforms by mesotrophic to eutrophic platforms. The first crisis occurred during Valanginian and Hauterivian

  7. The safety R and D for GEN-IV reactors in the European nuclear energy technology platform strategic research agenda

    International Nuclear Information System (INIS)

    Bruna, G.

    2009-01-01

    In the fall 2007 EC launched the Sustainable Nuclear Energy Technology Platform (SNE-TP). The SNE-TP governing board set-up three working groups (WG): 1) Strategic Research Agenda (SRA) WG, in charge of drafting road-maps to support research, development and demonstration for current and future NPPs; 2) Deployment Strategy (DS) WG, in charge of defining the research road-map implementation and 3) Education, Training and Knowledge management (ETKM) WG, which was aimed at issuing proposal to reinforce European education and attract young in the nuclear field. The SRA WG was mandated to prepare the SRA vision document based on the preliminary road-map sketched in the document published by the Commission earlier in 2007. The SRA WG was originally organized in 5 sub-groups covering specific topics (1) GEN II and III, III+, including Advanced LWR, 2) Advanced Fuel Cycle for waste minimization and resource optimization; 3) GEN IV Fast Systems (SFR, LFR, GFR, ADS); 4) GEN IV (V) HTR and non-electricity-production applications; 5) New Nuclear Large Research Infrastructures) and 5 other sub-groups dealing with more generic cross-cutting research activities applicable to many specific topics, namely: 1) Structural material research; 2) modeling, simulation and methods, including physical data and tools and means for qualification and validation; 3) Reactor Safety, including severe accidents and human factor; 4) Advanced Driver and Minor Actinide Fuels: science and properties; 5) Pre-normative Research, Codes and Standards.The present paper is mainly aimed at summarizing the content of the SRA Safety sub-chapter focusing on GEN-IV aspects

  8. Helicopter flight simulation motion platform requirements

    Science.gov (United States)

    Schroeder, Jeffery Allyn

    Flight simulators attempt to reproduce in-flight pilot-vehicle behavior on the ground. This reproduction is challenging for helicopter simulators, as the pilot is often inextricably dependent on external cues for pilot-vehicle stabilization. One important simulator cue is platform motion; however, its required fidelity is unknown. To determine the required motion fidelity, several unique experiments were performed. A large displacement motion platform was used that allowed pilots to fly tasks with matched motion and visual cues. Then, the platform motion was modified to give cues varying from full motion to no motion. Several key results were found. First, lateral and vertical translational platform cues had significant effects on fidelity. Their presence improved performance and reduced pilot workload. Second, yaw and roll rotational platform cues were not as important as the translational platform cues. In particular, the yaw rotational motion platform cue did not appear at all useful in improving performance or reducing workload. Third, when the lateral translational platform cue was combined with visual yaw rotational cues, pilots believed the platform was rotating when it was not. Thus, simulator systems can be made more efficient by proper combination of platform and visual cues. Fourth, motion fidelity specifications were revised that now provide simulator users with a better prediction of motion fidelity based upon the frequency responses of their motion control laws. Fifth, vertical platform motion affected pilot estimates of steady-state altitude during altitude repositionings. This refutes the view that pilots estimate altitude and altitude rate in simulation solely from visual cues. Finally, the combined results led to a general method for configuring helicopter motion systems and for developing simulator tasks that more likely represent actual flight. The overall results can serve as a guide to future simulator designers and to today's operators.

  9. Experimental and Theoretical Analysis of a Combined Floating Wave and Wind Energy Conversion Platform

    DEFF Research Database (Denmark)

    Yde, Anders; Pedersen, Mads Mølgaard; Bellew, Sarah Bellew

    This report presents results from the PSO project 2011-1-10668 entitled Poseidon 2. The project is a continuation of the previous PSO project entitled Aero-Hydro-Elastic Simulation Platform for Wave Energy Systems and floating Wind Turbines. Floating Power Plant has developed the technology...... for a novel, floating, wave- and wind-energy hybrid device. To test the technology they have scaled the design to P37, a 37 m wide test platform that has been undergoing offshore testing for four complete test phases (totaling more than 2 years). The test platform provides electricity to the grid from both...... wind and wave energy, however its purpose is purely for research and development. The PSO project has equipped the platform with comprehensive measurements equipment for measuring platform motion, wave and wind conditions and turbine loads. Data from the test periods has been used for evaluating...

  10. A holistic approach to SIM platform and its application to early-warning satellite system

    Science.gov (United States)

    Sun, Fuyu; Zhou, Jianping; Xu, Zheyao

    2018-01-01

    This study proposes a new simulation platform named Simulation Integrated Management (SIM) for the analysis of parallel and distributed systems. The platform eases the process of designing and testing both applications and architectures. The main characteristics of SIM are flexibility, scalability, and expandability. To improve the efficiency of project development, new models of early-warning satellite system were designed based on the SIM platform. Finally, through a series of experiments, the correctness of SIM platform and the aforementioned early-warning satellite models was validated, and the systematical analyses for the orbital determination precision of the ballistic missile during its entire flight process were presented, as well as the deviation of the launch/landing point. Furthermore, the causes of deviation and prevention methods will be fully explained. The simulation platform and the models will lay the foundations for further validations of autonomy technology in space attack-defense architecture research.

  11. Physical and chemical data collected using bottle casts in a World-wide distribution from NOAA Ship RESEARCHER and other platforms from 1911-11-11 to 1990-03-18 (NODC Accession 9600072)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Physical and chemical data were collected using bottle casts in a World-wide distribution from NOAA Ship RESEARCHER and other platforms from 11 November 1911 to 18...

  12. Distributed Fracturing Affecting the Isolated Carbonate Platforms, the Latemar Platform (Dolomites, North Italy).

    NARCIS (Netherlands)

    Boro, H.; Bertotti, G.V.; Hardebol, N.J.

    2012-01-01

    Isolated carbonate platforms are highly heterogeneous bodies and are typically composed of laterally juxtaposed first order domains with different sedimentological composition and organization, i.e. a well-stratified platform interior, a massive margin and a slope with steeply dipping and poorly

  13. Kameleon Live: An Interactive Cloud Based Analysis and Visualization Platform for Space Weather Researchers

    Science.gov (United States)

    Pembroke, A. D.; Colbert, J. A.

    2015-12-01

    The Community Coordinated Modeling Center (CCMC) provides hosting for many of the simulations used by the space weather community of scientists, educators, and forecasters. CCMC users may submit model runs through the Runs on Request system, which produces static visualizations of model output in the browser, while further analysis may be performed off-line via Kameleon, CCMC's cross-language access and interpolation library. Off-line analysis may be suitable for power-users, but storage and coding requirements present a barrier to entry for non-experts. Moreover, a lack of a consistent framework for analysis hinders reproducibility of scientific findings. To that end, we have developed Kameleon Live, a cloud based interactive analysis and visualization platform. Kameleon Live allows users to create scientific studies built around selected runs from the Runs on Request database, perform analysis on those runs, collaborate with other users, and disseminate their findings among the space weather community. In addition to showcasing these novel collaborative analysis features, we invite feedback from CCMC users as we seek to advance and improve on the new platform.

  14. A cloud collaborative medical image platform oriented by social network

    Science.gov (United States)

    Muniz, Frederico B.; Araújo, Luciano V.; Nunes, Fátima L. S.

    2017-03-01

    Computer-aided diagnosis systems using medical images and three-dimensional models as input data have greatly expanded and developed, but in terms of building suitable image databases to assess them, the challenge remains. Although there are some image databases available for this purpose, they are generally limited to certain types of exams or contain a limited number of medical cases. The objective of this work is to present the concepts and the development of a collaborative platform for sharing medical images and three-dimensional models, providing a resource to share and increase the number of images available for researchers. The collaborative cloud platform, called CATALYZER, aims to increase the availability and sharing of graphic objects, including 3D images, and their reports that are essential for research related to medical images. A survey conducted with researchers and health professionals indicated that this could be an innovative approach in the creation of medical image databases, providing a wider variety of cases together with a considerable amount of shared information among its users.

  15. Biomolecule-embedded metal-organic frameworks as an innovative sensing platform.

    Science.gov (United States)

    Kempahanumakkagari, Sureshkumar; Kumar, Vanish; Samaddar, Pallabi; Kumar, Pawan; Ramakrishnappa, Thippeswamy; Kim, Ki-Hyun

    Technological advancements combined with materials research have led to the generation of enormous types of novel substrates and materials for use in various biological/medical, energy, and environmental applications. Lately, the embedding of biomolecules in novel and/or advanced materials (e.g., metal-organic frameworks (MOFs), nanoparticles, hydrogels, graphene, and their hybrid composites) has become a vital research area in the construction of an innovative platform for various applications including sensors (or biosensors), biofuel cells, and bioelectronic devices. Due to the intriguing properties of MOFs (e.g., framework architecture, topology, and optical properties), they have contributed considerably to recent progresses in enzymatic catalysis, antibody-antigen interactions, or many other related approaches. Here, we aim to describe the different strategies for the design and synthesis of diverse biomolecule-embedded MOFs for various sensing (e.g., optical, electrochemical, biological, and miscellaneous) techniques. Additionally, the benefits and future prospective of MOFs-based biomolecular immobilization as an innovative sensing platform are discussed along with the evaluation on their performance to seek for further development in this emerging research area. Copyright © 2018. Published by Elsevier Inc.

  16. Analysis of human plasma metabolites across different liquid chromatography/mass spectrometry platforms: Cross-platform transferable chemical signatures.

    Science.gov (United States)

    Telu, Kelly H; Yan, Xinjian; Wallace, William E; Stein, Stephen E; Simón-Manso, Yamil

    2016-03-15

    The metabolite profiling of a NIST plasma Standard Reference Material (SRM 1950) on different liquid chromatography/mass spectrometry (LC/MS) platforms showed significant differences. Although these findings suggest caution when interpreting metabolomics results, the degree of overlap of both profiles allowed us to use tandem mass spectral libraries of recurrent spectra to evaluate to what extent these results are transferable across platforms and to develop cross-platform chemical signatures. Non-targeted global metabolite profiles of SRM 1950 were obtained on different LC/MS platforms using reversed-phase chromatography and different chromatographic scales (conventional HPLC, UHPLC and nanoLC). The data processing and the metabolite differential analysis were carried out using publically available (XCMS), proprietary (Mass Profiler Professional) and in-house software (NIST pipeline). Repeatability and intermediate precision showed that the non-targeted SRM 1950 profiling was highly reproducible when working on the same platform (relative standard deviation (RSD) HPLC, UHPLC and nanoLC) on the same platform. A substantial degree of overlap (common molecular features) was also found. A procedure to generate consistent chemical signatures using tandem mass spectral libraries of recurrent spectra is proposed. Different platforms rendered significantly different metabolite profiles, but the results were highly reproducible when working within one platform. Tandem mass spectral libraries of recurrent spectra are proposed to evaluate the degree of transferability of chemical signatures generated on different platforms. Chemical signatures based on our procedure are most likely cross-platform transferable. Published in 2016. This article is a U.S. Government work and is in the public domain in the USA.

  17. Development of a Common Format of Questionnaire Tests for a Web-based Platform of Population and Experimental Psychological Research

    Directory of Open Access Journals (Sweden)

    Nikulchev Evgeny

    2018-01-01

    Full Text Available A web platform for psychological research needs a single format of questionnaire tests to ensure interaction between its components. The study proposes a general test structure, variant questions, variations in response types, and an embedded domain-specific language for computations. The use of JSON is proposed and justified to store the hierarchical structure of the questionnaire test, and JSON Schema is defined as a technology suitable for the formation of the standard. From the considered validation instruments for compliance with the standard described in JSON Schema, ajv was defined as the most applicable to the task. To build the documentation, Doca is relevant, but this tool needs to be modified to meet the requirements of the task.

  18. Morphological indicators of growth stages in carbonates platform evolution: comparison between present-day and Miocene platforms of Northern Borneo, Malaysia.

    Science.gov (United States)

    Pierson, B.; Menier, D.; Ting, K. K.; Chalabi, A.

    2012-04-01

    Satellite images of present-day reefs and carbonate platforms of the Celebes Sea, east of Sabah, Malaysia, exhibit large-scale features indicative of the recent evolution of the platforms. These include: (1) multiple, sub-parallel reef rims at the windward margin, suggestive of back-stepping of the platform margin; (2) contraction of the platform, possibly as a result of recent sea level fluctuations; (3) colonization of the internal lagoons by polygonal reef structures and (4) fragmentation of the platforms and creation of deep channels separating platforms that used to be part of a single entity. These features are analogue to what has been observed on seismic attribute maps of Miocene carbonate platforms of Sarawak. An analysis of several growth stages of a large Miocene platform, referred to as the Megaplatform, shows that the platform evolves in function of syn-depositional tectonic movements and sea level fluctuations that result in back-stepping of the margin, illustrated by multiple reef rims, contraction of the platform, the development of polygonal structures currently interpreted as karstic in origin and fragmentation of the megaplatform in 3 sub-entities separated by deep channels that precedes the final demise of the whole platform. Comparing similar features on present-day to platforms and Miocene platforms leads to a better understanding of the growth history of Miocene platforms and to a refined predictability of reservoir and non-reservoir facies distribution.

  19. Towards a Framework of Digital Platform Disruption

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    2014-01-01

    Digital platforms are disruptive information technology (IT) artifacts that erode conventional business logic associated with traditional market structures. This paper presents a framework for examining the disruptive potential of digital platforms whereby we postulate that the strategic interplay...... digital platforms purposely decouple platform layers, to foster open innovation and accelerate market disruption. This paper therefore represents a first concrete step aimed at unravelling the disruptive potential of digital platforms....... of governance regimes and platform layers is deterministic of whether disruptive derivatives are permitted to flourish. This framework has been employed in a comparative case study between centralized (i.e., PayPal) and decentralized (i.e., Coinkite) digital payment platforms to illustrate its applicability...

  20. Mission Exploitation Platform PROBA-V

    Science.gov (United States)

    Goor, Erwin

    2016-04-01

    VITO and partners developed an end-to-end solution to drastically improve the exploitation of the PROBA-V EO-data archive (http://proba-v.vgt.vito.be/), the past mission SPOT-VEGETATION and derived vegetation parameters by researchers, service providers and end-users. The analysis of time series of data (+1PB) is addressed, as well as the large scale on-demand processing of near real-time data. From November 2015 an operational Mission Exploitation Platform (MEP) PROBA-V, as an ESA pathfinder project, will be gradually deployed at the VITO data center with direct access to the complete data archive. Several applications will be released to the users, e.g. - A time series viewer, showing the evolution of PROBA-V bands and derived vegetation parameters for any area of interest. - Full-resolution viewing services for the complete data archive. - On-demand processing chains e.g. for the calculation of N-daily composites. - A Virtual Machine will be provided with access to the data archive and tools to work with this data, e.g. various toolboxes and support for R and Python. After an initial release in January 2016, a research platform will gradually be deployed allowing users to design, debug and test applications on the platform. From the MEP PROBA-V, access to Sentinel-2 and landsat data will be addressed as well, e.g. to support the Cal/Val activities of the users. Users can make use of powerful Web based tools and can self-manage virtual machines to perform their work on the infrastructure at VITO with access to the complete data archive. To realise this, private cloud technology (openStack) is used and a distributed processing environment is built based on Hadoop. The Hadoop ecosystem offers a lot of technologies (Spark, Yarn, Accumulo, etc.) which we integrate with several open-source components. The impact of this MEP on the user community will be high and will completely change the way of working with the data and hence open the large time series to a larger

  1. Activities Based on Wiki Platform for Engineering Higher Education: Students' Point of View

    Directory of Open Access Journals (Sweden)

    Gláucia Nolasco de Almeida Mello

    2017-08-01

    Full Text Available The fast evolution of Information and Communication Technology (ICT introduced a new generation of learners that have been adopted mobile devices and Web 2.0 technologies to get information and communicate. The Web 2.0-based tools, such as blogs, wikis, Facebook, Instagram, etc, offer huge possibilities for collaboration. In this way, the main purpose of this research was plan an activity on wiki platform for Reinforced Concrete discipline in Civil Engineering course and answer the questions: (1 How should collaboration be effectively measured on wiki platform? (2 What is the students' point of view about using wiki platform for a collaboration activity? Wikispaces Classroom platform was chosen for the project because it is a free social writing platform, suitable for collaborative learning. Furthermore it works on modern browsers, tablets, and smart phone. A total of 167 students of Civil Engineering course were monitored on Wikispaces® platform. All students’ actions were analyzed and classified as low, medium or high level of collaboration. At the end of the project 111 students answered a questionnaire and 10 students participated of an informal interview where they expressed their opinion about the platform, the activities and the relationship with online peers. A descriptive statistical analysis of the data collected from the platform and the questionnaires answered by the students was performed. The results indicated that wiki platform is an important way to develop innovative activities and tasks for the purpose of to improve skills of engineering students such as: writing communication, organization, collaboration and critical thinking.

  2. CISP: Simulation Platform for Collective Instabilities in the BRing of HIAF project

    Science.gov (United States)

    Liu, J.; Yang, J. C.; Xia, J. W.; Yin, D. Y.; Shen, G. D.; Li, P.; Zhao, H.; Ruan, S.; Wu, B.

    2018-02-01

    To simulate collective instabilities during the complicated beam manipulation in the BRing (Booster Ring) of HIAF (High Intensity heavy-ion Accelerator Facility) or other high intensity accelerators, a code, named CISP (Simulation Platform for Collective Instabilities), is designed and constructed in China's IMP (Institute of Modern Physics). The CISP is a scalable multi-macroparticle simulation platform that can perform longitudinal and transverse tracking when chromaticity, space charge effect, nonlinear magnets and wakes are included. And due to its well object-oriented design, the CISP is also a basic platform used to develop many other applications (like feedback). Several simulations, completed by the CISP in this paper, agree with analytical results very well, which shows that the CISP is fully functional now and it is a powerful platform for the further collective instability research in the BRing or other accelerators. In the future, the CISP can also be extended easily into a physics control system for HIAF or other facilities.

  3. Anser EMT: the first open-source electromagnetic tracking platform for image-guided interventions.

    Science.gov (United States)

    Jaeger, Herman Alexander; Franz, Alfred Michael; O'Donoghue, Kilian; Seitel, Alexander; Trauzettel, Fabian; Maier-Hein, Lena; Cantillon-Murphy, Pádraig

    2017-06-01

    Electromagnetic tracking is the gold standard for instrument tracking and navigation in the clinical setting without line of sight. Whilst clinical platforms exist for interventional bronchoscopy and neurosurgical navigation, the limited flexibility and high costs of electromagnetic tracking (EMT) systems for research investigations mitigate against a better understanding of the technology's characterisation and limitations. The Anser project provides an open-source implementation for EMT with particular application to image-guided interventions. This work provides implementation schematics for our previously reported EMT system which relies on low-cost acquisition and demodulation techniques using both National Instruments and Arduino hardware alongside MATLAB support code. The system performance is objectively compared to other commercial tracking platforms using the Hummel assessment protocol. Positional accuracy of 1.14 mm and angular rotation accuracy of [Formula: see text] are reported. Like other EMT platforms, Anser is susceptible to tracking errors due to eddy current and ferromagnetic distortion. The system is compatible with commercially available EMT sensors as well as the Open Network Interface for image-guided therapy (OpenIGTLink) for easy communication with visualisation and medical imaging toolkits such as MITK and 3D Slicer. By providing an open-source platform for research investigations, we believe that novel and collaborative approaches can overcome the limitations of current EMT technology.

  4. Product Platform Development in Industrial Networks

    DEFF Research Database (Denmark)

    Karlsson, Christer; Skold, Martin

    2011-01-01

    The article examines the strategic issues involved in the deployment of product platform development in an industrial network. The move entails identifying the types and characteristics of generically different product platform strategies and clarifying strategic motives and differences. Number o...... of platforms and product brands serve as the key dimensions when distinguishing the different strategies. Each strategy has its own challenges and raises various issues to deal with.......The article examines the strategic issues involved in the deployment of product platform development in an industrial network. The move entails identifying the types and characteristics of generically different product platform strategies and clarifying strategic motives and differences. Number...

  5. AZTLAN platform: Mexican platform for analysis and design of nuclear reactors; AZTLAN platform: plataforma mexicana para el analisis y diseno de reactores nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Gomez T, A. M.; Puente E, F. [ININ, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico); Del Valle G, E. [IPN, Escuela Superior de Fisica y Matematicas, Av. IPN s/n, Edif. 9, Col. San Pedro Zacatenco, 07738 Mexico D. F. (Mexico); Francois L, J. L.; Martin del Campo M, C. [UNAM, Facultad de Ingenieria, Departamento de Sistemas Energeticos, Paseo Cuauhnahuac 8532, 62550 Jiutepec, Morelos (Mexico); Espinosa P, G., E-mail: armando.gomez@inin.gob.mx [Universidad Autonoma Metropolitana, Unidad Iztapalapa, Av. San Rafael Atlixco No. 186, Col. Vicentina, 09340 Mexico D. F. (Mexico)

    2014-10-15

    The Aztlan platform Project is a national initiative led by the Instituto Nacional de Investigaciones Nucleares (ININ) which brings together the main public houses of higher studies in Mexico, such as: Instituto Politecnico Nacional, Universidad Nacional Autonoma de Mexico and Universidad Autonoma Metropolitana in an effort to take a significant step toward the calculation autonomy and analysis that seeks to place Mexico in the medium term in a competitive international level on software issues for analysis of nuclear reactors. This project aims to modernize, improve and integrate the neutron, thermal-hydraulic and thermo-mechanical codes, developed in Mexican institutions, within an integrated platform, developed and maintained by Mexican experts to benefit from the same institutions. This project is financed by the mixed fund SENER-CONACYT of Energy Sustain ability, and aims to strengthen substantially to research institutions, such as educational institutions contributing to the formation of highly qualified human resources in the area of analysis and design of nuclear reactors. As innovative part the project includes the creation of a user group, made up of members of the project institutions as well as the Comision Nacional de Seguridad Nuclear y Salvaguardias, Central Nucleoelectrica de Laguna Verde (CNLV), Secretaria de Energia (Mexico) and Karlsruhe Institute of Technology (Germany) among others. This user group will be responsible for using the software and provide feedback to the development equipment in order that progress meets the needs of the regulator and industry; in this case the CNLV. Finally, in order to bridge the gap between similar developments globally, they will make use of the latest super computing technology to speed up calculation times. This work intends to present to national nuclear community the project, so a description of the proposed methodology is given, as well as the goals and objectives to be pursued for the development of the

  6. The universal modular platform

    International Nuclear Information System (INIS)

    North, R.B.

    1995-01-01

    A new and patented design for offshore wellhead platforms has been developed to meet a 'fast track' requirement for increased offshore production, from field locations not yet identified. The new design uses modular construction to allow for radical changes in the water depth of the final location and assembly line efficiency in fabrication. By utilizing high strength steels and structural support from the well conductors the new design accommodates all planned production requirements on a support structure significantly lighter and less expensive than the conventional design it replaces. Twenty two platforms based on the new design were ready for installation within 18 months of the project start. Installation of the new platforms began in 1992 for drilling support and 1993 for production support. The new design has become the Company standard for all future production platforms. Large saving and construction costs have been realized through its light weight, flexibility in both positioning and water depth, and its modular construction

  7. Throttleable GOX/ABS launch assist hybrid rocket motor for small scale air launch platform

    Science.gov (United States)

    Spurrier, Zachary S.

    Aircraft-based space-launch platforms allow operational flexibility and offer the potential for significant propellant savings for small-to-medium orbital payloads. The NASA Armstrong Flight Research Center's Towed Glider Air-Launch System (TGALS) is a small-scale flight research project investigating the feasibility for a remotely-piloted, towed, glider system to act as a versatile air launch platform for nano-scale satellites. Removing the crew from the launch vehicle means that the system does not have to be human rated, and offers a potential for considerable cost savings. Utah State University is developing a small throttled launch-assist system for the TGALS platform. This "stage zero" design allows the TGALS platform to achieve the required flight path angle for the launch point, a condition that the TGALS cannot achieve without external propulsion. Throttling is required in order to achieve and sustain the proper launch attitude without structurally overloading the airframe. The hybrid rocket system employs gaseous-oxygen and acrylonitrile butadiene styrene (ABS) as propellants. This thesis summarizes the development and testing campaign, and presents results from the clean-sheet design through ground-based static fire testing. Development of the closed-loop throttle control system is presented.

  8. The Rise of Ridesharing Platforms: an Uber-assessment of Bits and atoms

    OpenAIRE

    Ofstad, Magnus

    2017-01-01

    This thesis is a case study of Uber. The research questions are 1. How do ridesharing platforms evolve from startups into large-scale market disrupters? 2. How can ridesharing platforms augment its user base and capture more segments within the transportation business? Uber’s scaling is traditional. The initial growth consisted of capturing the high end of the market. Later on, Uber moved down market, making ridesharing affordable for the masses. The master stroke was to devise a scalable bus...

  9. The Platform Architecture and Key Technology of Cloud Service that Support Wisdom City Management

    Directory of Open Access Journals (Sweden)

    Liang Xiao

    2013-05-01

    Full Text Available According to the new requirement of constructing “resource sharing and service on demand” wisdom city system, this paper put forward the platform architecture of cloud service for wisdom city management which support IaaS, PaaS and SaaS three types of service model on the basis of researching the operation mode of the wisdom city which under cloud computing environment and through the research of mass storing technology of cloud data, building technology of cloud resource pool, scheduling management methods and monitoring technology of cloud resource, security management and control technology of cloud platform and other key technologies. The platform supports wisdom city system to achieve business or resource scheduling management optimization and the unified and efficient management of large-scale hardware and software, which has the characteristics of cross-domain resource scheduling, cross-domain data sharing, cross-domain facilities integration and cross-domain service integration.

  10. STI for Development in Asia : a Platform for Information Sharing and ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    This project will make use of available information technology platforms and regional ... (especially Southeast Asia) to share experiences and learning on the subject of STI. ... Eleven world-class research teams set to improve livestock vaccine ...

  11. Comparison of microarray platforms for measuring differential microRNA expression in paired normal/cancer colon tissues.

    Directory of Open Access Journals (Sweden)

    Maurizio Callari

    Full Text Available BACKGROUND: Microarray technology applied to microRNA (miRNA profiling is a promising tool in many research fields; nevertheless, independent studies characterizing the same pathology have often reported poorly overlapping results. miRNA analysis methods have only recently been systematically compared but only in few cases using clinical samples. METHODOLOGY/PRINCIPAL FINDINGS: We investigated the inter-platform reproducibility of four miRNA microarray platforms (Agilent, Exiqon, Illumina, and Miltenyi, comparing nine paired tumor/normal colon tissues. The most concordant and selected discordant miRNAs were further studied by quantitative RT-PCR. Globally, a poor overlap among differentially expressed miRNAs identified by each platform was found. Nevertheless, for eight miRNAs high agreement in differential expression among the four platforms and comparability to qRT-PCR was observed. Furthermore, most of the miRNA sets identified by each platform are coherently enriched in data from the other platforms and the great majority of colon cancer associated miRNA sets derived from the literature were validated in our data, independently from the platform. Computational integration of miRNA and gene expression profiles suggested that anti-correlated predicted target genes of differentially expressed miRNAs are commonly enriched in cancer-related pathways and in genes involved in glycolysis and nutrient transport. CONCLUSIONS: Technical and analytical challenges in measuring miRNAs still remain and further research is required in order to increase consistency between different microarray-based methodologies. However, a better inter-platform agreement was found by looking at miRNA sets instead of single miRNAs and through a miRNAs - gene expression integration approach.

  12. Pemetaan Platform Media Komunikasi Pemasaran PT. Dyandra Promosindo dalam Ruang Publik di Surabaya

    OpenAIRE

    Putra, Bayu Pratama; Prasetyo, Iwan Joko

    2017-01-01

     This study aims to determine the mapping of marketing communication media platform conducted by PT. Dyandra Promosindo Surabaya in the exhibition of Indie Clothing Expo 8th. This study discusses mapping of marketing communication media platform through promotion mix seen from the use of advertising element, personal selling, and direct marketing. The analysis of this research using qualitative approach with descriptive method, data collecting technique is with documentation, in-depth intervi...

  13. Development of an optoelectronic holographic platform for otolaryngology applications

    Science.gov (United States)

    Harrington, Ellery; Dobrev, Ivo; Bapat, Nikhil; Flores, Jorge Mauricio; Furlong, Cosme; Rosowski, John; Cheng, Jeffery Tao; Scarpino, Chris; Ravicz, Michael

    2010-08-01

    In this paper, we present advances on our development of an optoelectronic holographic computing platform with the ability to quantitatively measure full-field-of-view nanometer-scale movements of the tympanic membrane (TM). These measurements can facilitate otologists' ability to study and diagnose hearing disorders in humans. The holographic platform consists of a laser delivery system and an otoscope. The control software, called LaserView, is written in Visual C++ and handles communication and synchronization between hardware components. It provides a user-friendly interface to allow viewing of holographic images with several tools to automate holography-related tasks and facilitate hardware communication. The software uses a series of concurrent threads to acquire images, control the hardware, and display quantitative holographic data at video rates and in two modes of operation: optoelectronic holography and lensless digital holography. The holographic platform has been used to perform experiments on several live and post-mortem specimens, and is to be deployed in a medical research environment with future developments leading to its eventual clinical use.

  14. Research on Image Transmission System Based on 3G Communication Platform

    Directory of Open Access Journals (Sweden)

    Jingfeng Zang

    2014-07-01

    Full Text Available A wireless image real-time transmission system is designed by using 3G wireless communication platform and ARM + DSP embedded system. In the environment of 3G networks, the embedded equipment has realized the functions of coding, acquisition, network transmission, decoding and playing. It is realized for real-time video of intelligent control and video compression, storage and playback in the 3G embedded image transmission system. It is especially suitable for remote location or irregular cable network transmission conditions applications. It is shown that in the 3G network video files are transferred quickly. The real-time transmission of H.264 video is broadcasted smoothly, and color distortion is less. The server can control client by remote intelligent units.

  15. Twitter 101 and beyond: introduction to social media platforms available to practicing hematologist/oncologists.

    Science.gov (United States)

    Thompson, Michael A; Ahlstrom, Jenny; Dizon, Don S; Gad, Yash; Matthews, Greg; Luks, Howard J; Schorr, Andrew

    2017-10-01

    Social media utilizes specific media platforms to allow increased interactivity between participants. These platforms serve diverse groups and purposes including participation from patients, family caregivers, research scientists, physicians, and pharmaceutical companies. Utilization of these information outlets has increased with integration at conferences and between conferences with the use of hashtags and "chats". In the realm of the "e-Patient" it is key to not underestimate your audience. Highly technical information is just as useful as a basic post. With growing use, social media analytics help track the volume and impact of content. Additionally, platforms are leveraging each other for uses, including Twitter, blogs, web radio, and recorded video and images. We explore information on social media resources and applications from varying perspectives. While these platforms will evolve over time, or disappear with new platforms taking their place, it is apparent they are now a part of the everyday experience of oncology communication. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Improving nutrition surveillance and public health research in Central and Eastern Europe/Balkan Countries using the Balkan Food Platform and dietary tools.

    Science.gov (United States)

    Gurinović, Mirjana; Milešević, Jelena; Novaković, Romana; Kadvan, Agnes; Djekić-Ivanković, Marija; Šatalić, Zvonimir; Korošec, Mojca; Spiroski, Igor; Ranić, Marija; Dupouy, Eleonora; Oshaug, Arne; Finglas, Paul; Glibetić, Maria

    2016-02-15

    The objective of this paper is to share experience and provide updated information on Capacity Development in the Central and Eastern Europe/Balkan Countries (CEE/BC) region relevant to public health nutrition, particularly in creation of food composition databases (FCDBs), applying dietary intake assessment and monitoring tools, and harmonizing methodology for nutrition surveillance. Balkan Food Platform was established by a Memorandum of Understanding among EuroFIR AISBL, Institute for Medical Research, Belgrade, Capacity Development Network in Nutrition in CEE - CAPNUTRA and institutions from nine countries in the region. Inventory on FCDB status identified lack of harmonized and standardized research tools. To strengthen harmonization in CEE/BC in line with European research trends, the Network members collaborated in development of a Regional FCDB, using web-based food composition data base management software following EuroFIR standards. Comprehensive nutrition assessment and planning tool - DIET ASSESS & PLAN could enable synchronization of nutrition surveillance across countries. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Complex products and systems: potential from using lay out platforms

    NARCIS (Netherlands)

    Halman, Johannes I.M.; Hofer, Adrian P.

    2004-01-01

    In their quest to manage the complexity of offering greater product variety, firms in many industries are considering platform-based development of product families. Key in this approach is the sharing of components, modules, and other assets across a family of products. Current research indicates

  18. Using innovation platforms to scale out soil acidity-ameliorating ...

    African Journals Online (AJOL)

    An innovation platform comprising of farmers, government and NGO extension and researchers organized exchange tours and end of season review meetings. The number of farmers hosting the learning centers grew from 36 to 150 due to the IP interactions. At the end of the project support in 2008, the participating farmers ...

  19. Ethical sharing of health data in online platforms – which values should be considered?

    DEFF Research Database (Denmark)

    Riso, Brigida; Tupasela, Aaro Mikael; Vears, Danya

    2017-01-01

    Intensified and extensive data production and data storage are characteristics of contemporary western societies. Health data sharing is increasing with the growth of Information and Communication Technology (ICT) platforms devoted to the collection of personal health and genomic data. However...... and Ethical perspectives’ (IS 1303) identified six core values they considered to be essential for the ethical sharing of health data using ICT platforms. We believe that using this ethical framework will promote respectful scientific practices in order to maintain individuals’ trust in research. We use...... these values to analyse five ICT platforms and explore how emerging data sharing platforms are reconfiguring the data sharing experience from a range of perspectives. We discuss which types of values, rights and responsibilities they entail and enshrine within their philosophy or outlook on what it means...

  20. SNETP – Sustainable Nuclear Energy Technology Platform

    Energy Technology Data Exchange (ETDEWEB)

    Aït Abderrahim, Hamid

    2016-07-01

    SNETP is one of the EU’s official European Technology & Innovation Platforms established to implement the SET-Plan. SNETP and its pillars gather more than 120 European stakeholders involved in the research and innovation, deployment and operation of nuclear fission reactors and fuel cycle facilities: industry, research centres, universities, technical safety organisations, small and medium enterprises, service providers, non-governmental organisations. Despite industrial competition, SNETP has achieved efficient collaboration between its stakeholders. It has developed a common vision on the future contribution of nuclear fission energy in Europe, with the publication of a Vision Report, a Strategic Research & Innovation Agenda (two editions) and a Deployment Strategy report. It issued also a dedicated report on the R&D topics related to safety issues triggered by the Fukushima accident.

  1. New offshore platform in the Mexican Gulf

    Energy Technology Data Exchange (ETDEWEB)

    Beisel, T.

    1982-04-01

    After a construction period of only 10 months, the second steel Offshore platform was recently completed in the Mexican Gulf. The pattern for this structure was the Cognac platform. The erection of the new platform, called the 'Cerveza' platform, is described in the article.

  2. Sinking offshore platform. Nedsenkbar fralandsplatform

    Energy Technology Data Exchange (ETDEWEB)

    Einstabland, T.B.; Olsen, O.

    1988-12-19

    The invention deals with a sinking offshore platform of the gravitational type designed for being installed on the sea bed on great depths. The platform consists of at least three inclining pillars placed on a foundation unit. The pillars are at the upper end connected to a tower structure by means of a rigid construction. The tower supports the platform deck. The rigid construction comprises a centre-positioned cylinder connected to the foundation. 11 figs.

  3. Understanding Platform-Based Digital Currencies

    OpenAIRE

    Ben Fung; Hanna Halaburda

    2014-01-01

    Given technological advances and the widespread use of the Internet, various digital currencies have emerged. In most cases, Internet platforms such as Facebook and Amazon restrict the functionality of their digital currencies to enhance the business model and maximize their profits. While platform-based digital currencies could increase the efficiency of retail payments, they could also raise some important policy issues if they were to become widely used outside of the platform. Thus, it is...

  4. Evolutionary space platform concept study. Volume 2, part B: Manned space platform concepts

    Science.gov (United States)

    1982-01-01

    Logical, cost-effective steps in the evolution of manned space platforms are investigated and assessed. Tasks included the analysis of requirements for a manned space platform, identifying alternative concepts, performing system analysis and definition of the concepts, comparing the concepts and performing programmatic analysis for a reference concept.

  5. Polymer-based platform for microfluidic systems

    Science.gov (United States)

    Benett, William [Livermore, CA; Krulevitch, Peter [Pleasanton, CA; Maghribi, Mariam [Livermore, CA; Hamilton, Julie [Tracy, CA; Rose, Klint [Boston, MA; Wang, Amy W [Oakland, CA

    2009-10-13

    A method of forming a polymer-based microfluidic system platform using network building blocks selected from a set of interconnectable network building blocks, such as wire, pins, blocks, and interconnects. The selected building blocks are interconnectably assembled and fixedly positioned in precise positions in a mold cavity of a mold frame to construct a three-dimensional model construction of a microfluidic flow path network preferably having meso-scale dimensions. A hardenable liquid, such as poly (dimethylsiloxane) is then introduced into the mold cavity and hardened to form a platform structure as well as to mold the microfluidic flow path network having channels, reservoirs and ports. Pre-fabricated elbows, T's and other joints are used to interconnect various building block elements together. After hardening the liquid the building blocks are removed from the platform structure to make available the channels, cavities and ports within the platform structure. Microdevices may be embedded within the cast polymer-based platform, or bonded to the platform structure subsequent to molding, to create an integrated microfluidic system. In this manner, the new microfluidic platform is versatile and capable of quickly generating prototype systems, and could easily be adapted to a manufacturing setting.

  6. Testing RISKGIS Platform with Students to Improve Learning and Teaching Skills

    Science.gov (United States)

    Olyazadeh, R.; Aye, Z. C.; Jaboyedoff, M.; Derron, M. H.

    2016-12-01

    Nowadays, open-source developments in the field of natural hazards and risk management increase rapidly. The governments, NGOs and other research institutes are producing data for risk and disaster analysis, but a few platforms are available to bring a real-life experience to the students. This work focuses on the preliminary results of testing a WebGIS platform called RISKGIS with the bachelor students at the University of Lausanne. The platform is designed based on a geospatial open-source technology called OpenGeo (Boundless). This platform can calculate the potential risk of the buildings and assist the students to understand the situations for risk reduction mitigation and decision-making. The center of Jomsom in Nepal was selected for the first exercise that may be affected by amplifications of earthquake. The shaking intensity map was designed by an expert based on the geological characteristics and DEM (Digital Elevation Model) of the area. All buildings data were extracted from OpenStreetMap using QGIS and adapted to the platform. The video tutorial was prepared to guide the students through the platform, and 80 students have tested the application online successfully and 40 of them participated in Moodle (a free Open Source software package for educators) for online feedback and quiz. Among those, 30 of them have completely answered to both. We had interesting results for effectiveness, efficiency and satisfaction based on System Usability Scale (SUS). The SUS score for this platform was 68.6 out of 100. The average result of the quiz was 9.39 out of 10 with a duration of 8 to 33 minutes to answer the quiz. There were several outliers for this duration with 2 minutes (two students) and 9 to 18 hours (three students). Further exercises will be carried out with students by adding more advanced functions to the platform and improving the willingness of participation in this online learning platform. This project is funded by Fonds d'innovation p

  7. Temperature profile data collected using XBT and BT casts in a World-wide distribution from NOAA Ship RESEARCHER and other platforms from 1970-09-30 to 1979-08-05 (NODC Accession 8300089)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using XBT and BT casts from NOAA Ship RESEARCHER and other platforms in a World-wide distribution from 30 September 1970 to...

  8. Offshore Minerals Management Platforms for the Gulf of Mexico (GOM), Geographic NAD83, MMS (2006) [platforms_mms_2006

    Data.gov (United States)

    Louisiana Geographic Information Center — Offshore Minerals Management Platforms for the Gulf of Mexico (GOM). Identifies the location of platforms in GOM. All platforms existing in the database are included.

  9. Simulation platform for remote participants in fusion experiments

    International Nuclear Information System (INIS)

    Barrera, E.; Ruiz, M.; Lopez, S.; Vega, J.; Sanchez, E.

    2004-01-01

    One of the major challenges in remote participation in fusion experiments is the control from remote locations of the data acquisition and treatment process. In an optimum situation, the remote researcher should be able to control the data acquisition configuration parameters, and data processing, specifying the results that must be returned to him. The simulation platform presented here, allows the researcher to develop and test complex algorithms in a high level graphical language (LabVIEW), which includes powerful data processing libraries. These algorithms will be downloaded later into the data acquisition system. Furthermore, the platform allows the simulation of hardware data acquisition, which include the following points: (a) simulation of channel configuration from one or several data acquisition cards (channels used, sample frequencies, etc.), (b) generation of buffered simulated data (it is also possible the use of raw data, acquired in previous experiments, as simulated data), and (c) reproduction of hardware behavior (except, of course, in terms of real time behavior and real data). For this purpose, Virtual Instruments (VIs) libraries written in LabVIEW will be provided to the remote developers. These VIs will be replaced later, in the data acquisition system, by their homologous VIs that actually interface with the hardware. This facility will allow remote researchers to verify the correct behavior of their own data processing algorithms before downloading them into the data acquisition system

  10. Data Sharing and Cardiology: Platforms and Possibilities.

    Science.gov (United States)

    Dey, Pranammya; Ross, Joseph S; Ritchie, Jessica D; Desai, Nihar R; Bhavnani, Sanjeev P; Krumholz, Harlan M

    2017-12-19

    Sharing deidentified patient-level research data presents immense opportunities to all stakeholders involved in cardiology research and practice. Sharing data encourages the use of existing data for knowledge generation to improve practice, while also allowing for validation of disseminated research. In this review, we discuss key initiatives and platforms that have helped to accelerate progress toward greater sharing of data. These efforts are being prompted by government, universities, philanthropic sponsors of research, major industry players, and collaborations among some of these entities. As data sharing becomes a more common expectation, policy changes will be required to encourage and assist data generators with the process of sharing the data they create. Patients also will need access to their own data and to be empowered to share those data with researchers. Although medicine still lags behind other fields in achieving data sharing's full potential, cardiology research has the potential to lead the way. Copyright © 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  11. PDTCM: a systems pharmacology platform of traditional Chinese medicine for psoriasis.

    Science.gov (United States)

    Wang, Dongmei; Gu, Jiangyong; Zhu, Wei; Luo, Fang; Chen, Lirong; Xu, Xiaojie; Lu, Chuanjian

    2017-12-01

    Psoriasis is a refractory skin disorder, and usually requires a lifetime control. Traditional Chinese medicine (TCM) is effective and safe for this disease. However, the cellular and molecular mechanisms of TCM remedies for psoriasis are still not fully understood. TCM contains numerous natural products. Natural products have historically been invaluable as a resource of therapeutic agents. Yet, there is no integrated information about active compounds of TCM for psoriasis. We use systems pharmacology methods to develop the Psoriasis Database of Traditional Chinese Medicine (PDTCM). The database covered a number of psoriasis-related information (formulas, TCM, compounds, target proteins, diseases and biomarkers). With these data information, an online platform was constructed Results: PDTCM comprises 38 empirical therapeutic formulas, 34373 compounds from 1424 medicinal plants, 44 psoriasis-related proteins and 76 biomarkers from 111 related diseases. On this platform, users can screen active compounds for a psoriasis-related target and explore molecular mechanisms of TCM. Accordingly, users can also download the retrieved structures and data information with a defined value set. In addition, it helps to get a better understanding of Chinese prescriptions in disease treatment. With the systems pharmacology-based data, PDTCM would become a valuable resource for TCM in psoriasis-related research. Key messages PDTCM platform comprises a great deal of data on TCM and psoriasis. On this platform, users can retrieve and get needed information with systems pharmacology methods, such as active compounds screening, target prediction and molecular mechanisms exploration. It is a tool for psoriasis-related research on natural drugs systematically.

  12. NiftyNet: a deep-learning platform for medical imaging.

    Science.gov (United States)

    Gibson, Eli; Li, Wenqi; Sudre, Carole; Fidon, Lucas; Shakir, Dzhoshkun I; Wang, Guotai; Eaton-Rosen, Zach; Gray, Robert; Doel, Tom; Hu, Yipeng; Whyntie, Tom; Nachev, Parashkev; Modat, Marc; Barratt, Dean C; Ourselin, Sébastien; Cardoso, M Jorge; Vercauteren, Tom

    2018-05-01

    Medical image analysis and computer-assisted intervention problems are increasingly being addressed with deep-learning-based solutions. Established deep-learning platforms are flexible but do not provide specific functionality for medical image analysis and adapting them for this domain of application requires substantial implementation effort. Consequently, there has been substantial duplication of effort and incompatible infrastructure developed across many research groups. This work presents the open-source NiftyNet platform for deep learning in medical imaging. The ambition of NiftyNet is to accelerate and simplify the development of these solutions, and to provide a common mechanism for disseminating research outputs for the community to use, adapt and build upon. The NiftyNet infrastructure provides a modular deep-learning pipeline for a range of medical imaging applications including segmentation, regression, image generation and representation learning applications. Components of the NiftyNet pipeline including data loading, data augmentation, network architectures, loss functions and evaluation metrics are tailored to, and take advantage of, the idiosyncracies of medical image analysis and computer-assisted intervention. NiftyNet is built on the TensorFlow framework and supports features such as TensorBoard visualization of 2D and 3D images and computational graphs by default. We present three illustrative medical image analysis applications built using NiftyNet infrastructure: (1) segmentation of multiple abdominal organs from computed tomography; (2) image regression to predict computed tomography attenuation maps from brain magnetic resonance images; and (3) generation of simulated ultrasound images for specified anatomical poses. The NiftyNet infrastructure enables researchers to rapidly develop and distribute deep learning solutions for segmentation, regression, image generation and representation learning applications, or extend the platform to new

  13. PLUME and research sotware

    Science.gov (United States)

    Baudin, Veronique; Gomez-Diaz, Teresa

    2013-04-01

    The PLUME open platform (https://www.projet-plume.org) has as first goal to share competences and to value the knowledge of software experts within the French higher education and research communities. The project proposes in its platform the access to more than 380 index cards describing useful and economic software for this community, with open access to everybody. The second goal of PLUME focuses on to improve the visibility of software produced by research laboratories within the higher education and research communities. The "development-ESR" index cards briefly describe the main features of the software, including references to research publications associated to it. The platform counts more than 300 cards describing research software, where 89 cards have an English version. In this talk we describe the theme classification and the taxonomy of the index cards and the evolution with new themes added to the project. We will also focus on the organisation of PLUME as an open project and its interests in the promotion of free/open source software from and for research, contributing to the creation of a community of shared knowledge.

  14. Platformed antagonism: Racist discourses on fake Muslim Facebook pages

    DEFF Research Database (Denmark)

    Farkas, Johan; Schou, Jannick; Neumayer, Christina

    2018-01-01

    This research examines how fake identities on social media create and sustain antagonistic and racist discourses. It does so by analysing 11 Danish Facebook pages, disguised as Muslim extremists living in Denmark, conspiring to kill and rape Danish citizens. It explores how anonymous content...... producers utilize Facebook's socio-technical characteristics to construct, what we propose to term as, platformed antagonism. This term refers to socio-technical and discursive practices that produce new modes of antagonistic relations on social media platforms. Through a discourse-theoretical analysis...... of posts, images, 'about' sections and user comments on the studied Facebook pages, the article highlights how antagonism between ethno-cultural identities is produced on social media through fictitious social media accounts, prompting thousands of user reactions. These findings enhance our current...

  15. Choosing a Wiki Platform for Student Projects--Lessons Learned

    Science.gov (United States)

    Malaga, Ross A.

    2010-01-01

    Wikis offer many benefits, such as two-way flows of information, early and consistent feedback, and greater student group collaboration, in an educational setting. Some researchers have already reported on the use of Wikis in their classes. However, instructors must choose an appropriate Wiki platform in order to receive all of the benefits of…

  16. NASA Airborne Science Program: NASA Stratospheric Platforms

    Science.gov (United States)

    Curry, Robert E.

    2010-01-01

    The National Aeronautics and Space Administration conducts a wide variety of remote sensing projects using several unique aircraft platforms. These vehicles have been selected and modified to provide capabilities that are particularly important for geophysical research, in particular, routine access to very high altitudes, long range, long endurance, precise trajectory control, and the payload capacity to operate multiple, diverse instruments concurrently. While the NASA program has been in operation for over 30 years, new aircraft and technological advances that will expand the capabilities for airborne observation are continually being assessed and implemented. This presentation will review the current state of NASA's science platforms, recent improvements and new missions concepts as well as provide a survey of emerging technologies unmanned aerial vehicles for long duration observations (Global Hawk and Predator). Applications of information technology that allow more efficient use of flight time and the ability to rapidly reconfigure systems for different mission objectives are addressed.

  17. Temperature profile data collected using XBT and BT casts in a world-wide distribution from NOAA Ship RESEARCHER and other platforms from 1982-08-18 to 1982-12-21 (NODC Accession 8300007)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using XBT and BT casts from NOAA Ship RESEARCHER and other platforms in a world-wide distribution from 18 August 1982 to 21...

  18. E-based Humanities and E-humanities on a SURF platform

    NARCIS (Netherlands)

    Kircz, J.G.

    2004-01-01

    As of 2003, SURF enables three platforms: ICT and Research, Education, and Organisation. Within these programmes, SURF has funds available to promote ICT innovations. Innovation is not an easy notion to explain. Too often we encounter new wine in old bottles and changes in vocabulary frequently

  19. Data Collection for Mental Health Studies Through Digital Platforms: Requirements and Design of a Prototype.

    Science.gov (United States)

    Aledavood, Talayeh; Triana Hoyos, Ana Maria; Alakörkkö, Tuomas; Kaski, Kimmo; Saramäki, Jari; Isometsä, Erkki; Darst, Richard K

    2017-06-09

    described why each of these features are important for digital data collection for psychiatry, gave examples of projects where Niima was used or is going to be used in the future, and demonstrated how incorporating these design principles opens new possibilities for studies. The new methods of digital psychiatry are still immature and need further research. The design features we suggested are a first step to design platforms which can adapt to the upcoming requirements of digital psychiatry. ©Talayeh Aledavood, Ana Maria Triana Hoyos, Tuomas Alakörkkö, Kimmo Kaski, Jari Saramäki, Erkki Isometsä, Richard K Darst. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 09.06.2017.

  20. Towards a Framework of Digital Platform Competition

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    2016-01-01

    between monopolistic (i.e., Pingit) and federated (i.e., Paym) mobile payment platforms to illustrate its applicability and yield principles on the nature and impact of competition among platform-driven ubiquitous systems. Preliminary findings indicate that monopolistic mobile digital platforms attempt...... to create unique configurals to obtain monopolistic power by tightly coupling platform layers, which are difficult to replicate. Conversely, federated digital platforms compete by dispersing the service layer to harness the collective resources from individual firms. Furthermore, the interaction...

  1. AZTLAN: Mexican platform for analysis and design of nuclear reactors - 15493

    International Nuclear Information System (INIS)

    Gomez Torres, A.M.; Puente Espel, F.; Valle Gallegos, E. del; Francois, J.L.; Martin-del-Campo, C.; Espinosa-Paredes, G.

    2015-01-01

    The AZTLAN platform is presented in this paper. This project aims at modernizing, improving and incorporating the neutron transport codes such as AZTLAN, AZKIND and AZNHEX, thermo-hydraulics codes like AZTHECA and thermo-mechanical codes developed in the Mexican institutions of higher education as well as in the Mexican nuclear research institute, in an integrated platform, established and maintained for the benefit of the Mexican nuclear knowledge. An important part of the project is to develop a coupling methodology between neutron transport codes and thermal-hydraulics codes in order to get an accurate 3-dimensional simulation of a reactor core

  2. Development of a cloud-based Bioinformatics Training Platform.

    Science.gov (United States)

    Revote, Jerico; Watson-Haigh, Nathan S; Quenette, Steve; Bethwaite, Blair; McGrath, Annette; Shang, Catherine A

    2017-05-01

    The Bioinformatics Training Platform (BTP) has been developed to provide access to the computational infrastructure required to deliver sophisticated hands-on bioinformatics training courses. The BTP is a cloud-based solution that is in active use for delivering next-generation sequencing training to Australian researchers at geographically dispersed locations. The BTP was built to provide an easy, accessible, consistent and cost-effective approach to delivering workshops at host universities and organizations with a high demand for bioinformatics training but lacking the dedicated bioinformatics training suites required. To support broad uptake of the BTP, the platform has been made compatible with multiple cloud infrastructures. The BTP is an open-source and open-access resource. To date, 20 training workshops have been delivered to over 700 trainees at over 10 venues across Australia using the BTP. © The Author 2016. Published by Oxford University Press.

  3. Feasibility of a low-cost sounding rockoon platform

    Science.gov (United States)

    Okninski, Adam; Raurell, Daniel Sors; Mitre, Alberto Rodriguez

    2016-10-01

    This paper presents the results of analyses and simulations for the design of a small sounding platform, dedicated to conducting scientific atmospheric research and capable of reaching the von Kármán line by means of a rocket launched from it. While recent private initiatives have opted for the air launch concept to send small payloads to Low Earth Orbit, several historical projects considered the use of balloons as the first stage of orbital and suborbital platforms, known as rockoons. Both of these approaches enable the minimization of drag losses. This paper addresses the issue of utilizing stratospheric balloons as launch platforms to conduct sub-orbital rocket flights. Research and simulations have been conducted to demonstrate these capabilities and feasibility. A small sounding solid propulsion rocket using commercially-off-the-shelf hardware is proposed. Its configuration and design are analyzed with special attention given to the propulsion system and its possible mission-orientated optimization. The cost effectiveness of this approach is discussed. Performance calculation outcomes are shown. Additionally, sensitivity study results for different design parameters are given. Minimum mass rocket configurations for various payload requirements are presented. The ultimate aim is to enhance low-cost experimentation maintaining high mobility of the system and simplicity of operations. An easier and more affordable access to a space-like environment can be achieved with this system, thus allowing for widespread outreach of space science and technology knowledge. This project is based on earlier experience of the authors in LEEM Association of the Technical University of Madrid and the Polish Small Sounding Rocket Program developed at the Institute of Aviation and Warsaw University of Technology in Poland.

  4. Assembly procedure for Shot Loading Platform

    International Nuclear Information System (INIS)

    Routh, R.D.

    1995-01-01

    This supporting document describes the assembly procedure for the Shot Loading Platform. The Shot Loading Platform is used by multiple equipment removal projects to load shielding shot in the annular spaces of the equipment storage containers. The platform height is adjustable to accommodate different sizes of storage containers and transport assemblies

  5. Designing the RiverCare knowledge base and web-collaborative platform to exchange knowledge in river management

    Science.gov (United States)

    Cortes Arevalo, Juliette; den Haan, Robert-Jan; van der Voort, Mascha; Hulscher, Suzanne

    2016-04-01

    Effective communication strategies are necessary between different scientific disciplines, practitioners and non-experts for a shared understanding and better implementation of river management measures. In that context, the RiverCare program aims to get a better understanding of riverine measures that are being implemented towards self-sustaining multifunctional rivers in the Netherlands. During the RiverCare program, user committees are organized between the researchers and practitioners to discuss the aim and value of RiverCare outputs, related assumptions and uncertainties behind scientific results. Beyond the RiverCare program end, knowledge about river interventions, integrated effects, management and self-sustaining applications will be available to experts and non-experts by means of River Care communication tools: A web-collaborative platform and a serious gaming environment. As part of the communication project of RiverCare, we are designing the RiverCare web-collaborative platform and the knowledge-base behind that platform. We aim at promoting collaborative efforts and knowledge exchange in river management. However, knowledge exchange does not magically happen. Consultation and discussion of RiverCare outputs as well as elicitation of perspectives and preferences from different actors about the effects of riverine measures has to be facilitated. During the RiverCare research activities, the platform will support the user committees or collaborative sessions that are regularly held with the organizations directly benefiting from our research, at project level or in study areas. The design process of the collaborative platform follows an user centred approach to identify user requirements, co-create a conceptual design and iterative develop and evaluate prototypes of the platform. The envisioned web-collaborative platform opens with an explanation and visualisation of the RiverCare outputs that are available in the knowledge base. Collaborative sessions

  6. Development of jacket platform tsunami risk rating system in waters offshore North Borneo

    Science.gov (United States)

    Lee, H. E.; Liew, M. S.; Mardi, N. H.; Na, K. L.; Toloue, Iraj; Wong, S. K.

    2016-09-01

    This work details the simulation of tsunami waves generated by seaquakes in the Manila Trench and their effect on fixed oil and gas jacket platforms in waters offshore North Borneo. For this study, a four-leg living quarter jacket platform located in a water depth of 63m is modelled in SACS v5.3. Malaysia has traditionally been perceived to be safe from the hazards of earthquakes and tsunamis. Local design practices tend to neglect tsunami waves and include no such provisions. In 2004, a 9.3 M w seaquake occurred off the northwest coast of Aceh, which generated tsunami waves that caused destruction in Malaysia totalling US 25 million and 68 deaths. This event prompted an awareness of the need to study the reliability of fixed offshore platforms scattered throughout Malaysian waters. In this paper, we present a review of research on the seismicity of the Manila Trench, which is perceived to be high risk for Southeast Asia. From the tsunami numerical model TUNA-M2, we extract computer-simulated tsunami waves at prescribed grid points in the vicinity of the platforms in the region. Using wave heights as input, we simulate the tsunami using SACS v5.3 structural analysis software of offshore platforms, which is widely accepted by the industry. We employ the nonlinear solitary wave theory in our tsunami loading calculations for the platforms, and formulate a platform-specific risk quantification system. We then perform an intensive structural sensitivity analysis and derive a corresponding platform-specific risk rating model.

  7. Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images.

    Science.gov (United States)

    Spagnolo, Daniel M; Al-Kofahi, Yousef; Zhu, Peihong; Lezon, Timothy R; Gough, Albert; Stern, Andrew M; Lee, Adrian V; Ginty, Fiona; Sarachan, Brion; Taylor, D Lansing; Chennubhotla, S Chakra

    2017-11-01

    We introduce THRIVE (Tumor Heterogeneity Research Interactive Visualization Environment), an open-source tool developed to assist cancer researchers in interactive hypothesis testing. The focus of this tool is to quantify spatial intratumoral heterogeneity (ITH), and the interactions between different cell phenotypes and noncellular constituents. Specifically, we foresee applications in phenotyping cells within tumor microenvironments, recognizing tumor boundaries, identifying degrees of immune infiltration and epithelial/stromal separation, and identification of heterotypic signaling networks underlying microdomains. The THRIVE platform provides an integrated workflow for analyzing whole-slide immunofluorescence images and tissue microarrays, including algorithms for segmentation, quantification, and heterogeneity analysis. THRIVE promotes flexible deployment, a maintainable code base using open-source libraries, and an extensible framework for customizing algorithms with ease. THRIVE was designed with highly multiplexed immunofluorescence images in mind, and, by providing a platform to efficiently analyze high-dimensional immunofluorescence signals, we hope to advance these data toward mainstream adoption in cancer research. Cancer Res; 77(21); e71-74. ©2017 AACR . ©2017 American Association for Cancer Research.

  8. Building a Community-Focused Data Platform

    Energy Technology Data Exchange (ETDEWEB)

    Turk, Matthew J. [Univ. of Illinois, Urbana-Champaign, IL (United States). National Center for Supercomputing Applications (NCSA); Warren, Michael S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Skillman, Samuel W. [Stanford Univ., CA (United States)

    2014-06-10

    The National Data Service (NDS) presents a broad-reaching vision of integrating discovery, publishing, and sharing of data. Metcalfe's Law states that the value of a network increases with the number of connections in the network, not the number of nodes. The NDS must develop and steward connections not only between data, as is in its vision statement, but between individuals as well. We propose that this be accomplished by explicitly developing it as a platform on which data exploration can be constructed by individual researchers.

  9. Crowdfunding as an Alternative in Tourism: Analysis of Modus Operandi of Brazilian Platforms

    Directory of Open Access Journals (Sweden)

    Larissa Martins

    2017-04-01

    Full Text Available The crowdfunding system is a collective financing form in which people can contribute with money to projects they consider relevant, receiving or not compensation for this contribution. This paper aimed to analyze Brazilian situated crowdfunding platforms as an alternative to projects in tourism area. The research shows itself actual, faced to the recent growth of these platforms in the country. Also, it is relevant in a lack of resources scenario, once the method could interest by favoring credit access at the same time it promotes the targeted public involvement. By means of a descriptive, the existing platforms were verified: sixteen were found, twelve of which were analyzed, due to errors in the sites during the research period. Then, they were analyzed according to their modus operandi (existence of taxes, commission, “all-or-nothing system”, reward to the contributors, etc. and classified according to which enable the insertion of tourism projects. Half of the platforms contemplate several projects and, of these six, four consider Tourism. The most used model is “all-or-nothing” and the costs of this type of financing can reach more than thirty percent of the contributions, as they are charged management fees, transaction fees and even percentage for sales of the resulting product from crowdfunding. Thus, the system may be interesting to the entrepreneur, although it is necessary to consider operating costs.

  10. Ethical sharing of health data in online platforms - which values should be considered?

    Science.gov (United States)

    Riso, Brígida; Tupasela, Aaro; Vears, Danya F; Felzmann, Heike; Cockbain, Julian; Loi, Michele; Kongsholm, Nana C H; Zullo, Silvia; Rakic, Vojin

    2017-08-21

    Intensified and extensive data production and data storage are characteristics of contemporary western societies. Health data sharing is increasing with the growth of Information and Communication Technology (ICT) platforms devoted to the collection of personal health and genomic data. However, the sensitive and personal nature of health data poses ethical challenges when data is disclosed and shared even if for scientific research purposes.With this in mind, the Science and Values Working Group of the COST Action CHIP ME 'Citizen's Health through public-private Initiatives: Public health, Market and Ethical perspectives' (IS 1303) identified six core values they considered to be essential for the ethical sharing of health data using ICT platforms. We believe that using this ethical framework will promote respectful scientific practices in order to maintain individuals' trust in research.We use these values to analyse five ICT platforms and explore how emerging data sharing platforms are reconfiguring the data sharing experience from a range of perspectives. We discuss which types of values, rights and responsibilities they entail and enshrine within their philosophy or outlook on what it means to share personal health information. Through this discussion we address issues of the design and the development process of personal health data and patient-oriented infrastructures, as well as new forms of technologically-mediated empowerment.

  11. Temperature profile and other data collected using CTD casts in the TOGA Area - Pacific Ocean from NOAA Ship RESEARCHER and other platforms from 1984-11-13 to 1986-12-01 (NODC Accession 8700194)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile and other data were collected using CTD casts from NOAA Ship RESEARCHER and other platforms in the TOGA Area - Pacific Ocean from 13 November...

  12. Platform decisions supported by gaming

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Mikkola, Juliana Hsuan

    2007-01-01

    Platform is an ambiguous multidisciplinary concept. The philosophy behind it is easy to communicate and makes intuitively sense. However, the ease in communication does overshadow the high complexity when the concept is implemented. The practical industrial platform implementation challenge can...... be described as being a configuration problem with a high number of variables. These variables are different in nature; they have contradictory influence on the total performance, and, their importance change over time. Consequently, the specific platform decisions become highly complex and the consequences...

  13. Development of fast wireless detection system for fixed offshore platform

    Science.gov (United States)

    Li, Zhigang; Yu, Yan; Jiao, Dong; Wang, Jie; Li, Zhirui; Ou, Jinping

    2011-04-01

    Offshore platforms' security is concerned since in 1950s and 1960s, and in the early 1980s some important specifications and standards are built, and all these provide technical basis of fixed platform design, construction, installation and evaluation. With the condition that more and more platforms are in serving over age, the research about the evaluation and detection technology of offshore platform has been a hotspot, especially underwater detection, and assessment method based on the finite element calculation. For fixed platform structure detection, conventional NDT methods, such as eddy current, magnetic powder, permeate, X-ray and ultrasonic, etc, are generally used. These techniques are more mature, intuitive, but underwater detection needs underwater robot, the necessary supporting tools of auxiliary equipment, and trained professional team, thus resources and cost used are considerable, installation time of test equipment is long. This project presents a new kind of fast wireless detection and damage diagnosis system for fixed offshore platform using wireless sensor networks, that is, wireless sensor nodes can be put quickly on the offshore platform, detect offshore platform structure global status by wireless communication, and then make diagnosis. This system is operated simply, suitable for offshore platform integrity states rapid assessment. The designed system consists in intelligence acquisition equipment and 8 wireless collection nodes, the whole system has 64 collection channels, namely every wireless collection node has eight 16-bit accuracy of A/D channels. Wireless collection node, integrated with vibration sensing unit, embedded low-power micro-processing unit, wireless transceiver unit, large-capacity power unit, and GPS time synchronization unit, can finish the functions such as vibration data collection, initial analysis, data storage, data wireless transmission. Intelligence acquisition equipment, integrated with high

  14. Second report of the national platform electromobility; Zweiter Bericht der Nationalen Plattform Elektromobilitaet

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-05-15

    In the National Platform Electromobility, representatives from industry, science, politics, unions and societies in Germany agreed on a systematic, market-oriented and technology-open approach to become the main supplier and main market for electromobility up to the year 2020. A central component of the targeted German mean market for electromobility is an intelligent energy system: integration of electricity from renewable energy sources, demand-oriented development of a public charging infrastructure, development of an innovative charging structure. The common goal of the National Electromobility Platform is to build a self-supporting market for electric vehicles. The National Electromobility Platform will support the implementation of these intentions and measures. The underlying assumptions are reviewed annually. Derived recommendations are adapted, if necessary. Thus the National Electromobility Platform develops an annual progress report. With the end of the market scheduling phase by 2014, especially the market acceleration, demand for public infrastructure, costs and funding approaches for market acceleration as well as research and development will be re-evaluated.

  15. Digital platforms as enablers for digital transformation

    DEFF Research Database (Denmark)

    Hossain, Mokter; Lassen, Astrid Heidemann

    transformation is crucial. This study aims at exploring how organizations are driven towards transformation in various ways to embrace digital platforms for ideas, technologies, and knowledge. It shows the opportunities and challenges digital platforms bring in organizations. It also highlights underlying......Digital platforms offer new ways for organizations to collaborate with the external environment for ideas, technologies, and knowledge. They provide new possibilities and competence but they also bring new challenges for organizations. Understanding the role of these platforms in digital...... mechanisms and potential outcomes of various digital platforms. The contribution of the submission is valuable for scholars to understand and further explore this area. It provides insight for practitioners to capture value through digital platforms and accelerate the pace of organizations’ digital...

  16. [Orange Platform].

    Science.gov (United States)

    Toba, Kenji

    2017-07-01

    The Organized Registration for the Assessment of dementia on Nationwide General consortium toward Effective treatment in Japan (ORANGE platform) is a recently established nationwide clinical registry for dementia. This platform consists of multiple registries of patients with dementia stratified by the following clinical stages: preclinical, mild cognitive impairment, early-stage, and advanced-stage dementia. Patients will be examined in a super-longitudinal fashion, and their lifestyle, social background, genetic risk factors, and required care process will be assessed. This project is also notable because the care registry includes information on the successful, comprehensive management of patients with dementia. Therefore, this multicenter prospective cohort study will contribute participants to all clinical trials for Alzheimer's disease as well as improve the understanding of individuals with dementia.

  17. Evaluating the enhancement and improvement of China's technology and financial services platform innovation strategy.

    Science.gov (United States)

    Wu, Ching-Sung; Hu, Kuang-Hua; Chen, Fu-Hsiang

    2016-01-01

    The development of high-tech industry has been prosperous around the world in past decades, while technology and finance have already become the most significant issues in the information era. While high-tech firms are a major force behind a country's economic development, it requires a lot of money for the development process, as well as the financing difficulties for its potential problems, thus, how to evaluate and establish appropriate technology and financial services platforms innovation strategy has become one of the most critical and difficult issues. Moreover, how the chosen intertwined financial environment can be optimized in order that high-tech firms financing problems can be decided has seldom been addressed. Thus, this research aims to establish a technology and financial services platform innovation strategy improvement model, as based on the hybrid MADM model, which addresses the main causal factors and amended priorities in order to strengthen ongoing planning. A DEMATEL technique, as based on Analytic Network Process, as well as modified VIKOR, will be proposed for selecting and re-configuring the aspired technology and financial services platform. An empirical study, as based on China's technology and financial services platform innovation strategy, will be provided for verifying the effectiveness of this proposed methodology. Based on expert interviews, technology and financial services platforms innovation strategy improvement should be made in the following order: credit guarantee platform ( C )_credit rating platform ( B )_investment and finance platform ( A ).

  18. Development of system design and seismic performance evaluation for reactor pool working platform of a research reactor

    International Nuclear Information System (INIS)

    Kwag, Shinyoung; Lee, Jong-Min; Oh, Jinho; Ryu, Jeong-Soo

    2014-01-01

    Highlights: • Design of reactor pool working platform (RPWP) is newly proposed for an open-tank-in-pool type research reactor. • Main concept of RPWP is to minimize the pool top radiation level. • Framework for seismic performance evaluation of nuclear SSCs in a deterministic and a probabilistic manner is proposed. • Structural integrity, serviceability, and seismic margin of the RPWP are evaluated during and after seismic events. -- Abstract: The reactor pool working platform (RPWP) has been newly designed for an open-tank-in-pool type research reactor, and its seismic response, structural integrity, serviceability, and seismic margin have been evaluated during and after seismic events in this paper. The main important concept of the RPWP is to minimize the pool top radiation level by physically covering the reactor pool of the open-tank-in-pool type research reactor and suppressing the rise of flow induced by the primary cooling system. It is also to provide easy handling of the irradiated objects under the pool water by providing guide tubes and refueling cover to make the radioisotopes irradiated and protect the reactor structure assembly. For this concept, the new three dimensional design model of the RPWP is established for manufacturing, installation and operation, and the analytical model is developed to analyze the seismic performance. Since it is submerged under and influenced by water, the hydrodynamic effect is taken into account by using the hydrodynamic added mass method. To investigate the dynamic characteristics of the RPWP, a modal analysis of the developed analytical model is performed. To evaluate the structural integrity and serviceability of the RPWP, the response spectrum analysis and response time history analysis have been performed under the static load and the seismic load of a safe shutdown earthquake (SSE). Their stresses are analyzed for the structural integrity. The possibility of an impact between the RPWP and the most

  19. Graphene-Plasmonic Hybrid Platform for Label-Free SERS Biomedical Detection

    Science.gov (United States)

    Wang, Pu

    Surface Enhanced Raman Scattering (SERS) has attracted explosive interest for the wealth of vibrational information it provides with minimal invasive effects to target analyte. Nanotechnology, especially in the form of noble metal nanoparticles exhibit unique electromagnetic and chemical characteristics that are explored to realize ultra-sensitive SERS detection in chemical and biological analysis. Graphene, atom-thick carbon monolayer, exhibits superior chemical stability and bio-compatibility. A combination of SERS-active metal nanostructures and graphene will create various synergies in SERS. The main objective of this research was to exploit the applications of the graphene-Au tip hybrid platform in SERS. The hybrid platform consists of a periodic Au nano-pyramid substrate to provide reproducible plasmonic enhancement, and the superimposed monolayer graphene sheet, serving as "built-in" Raman marker. Extensive theoretical and experimental studies were conducted to determine the potentials of the hybrid platform as SERS substrate. Results from both Finite-Domain Time-Domain (FDTD) numerical simulation and Raman scattering of graphene suggested that the hybrid platform boosted a high density of hotspots yielding 1000 times SERS enhancement of graphene bands. Ultra-high sensitivity of the hybrid platform was demonstrated by bio-molecules including dye, protein and neurotransmitters. Dopamine and serotonin can be detected and distinguished at 10-9 M concentration in the presence of human body fluid. Single molecule detection was obtained using a bi-analyte technique. Graphene supported a vibration mode dependent SERS chemical enhancement of ˜10 to the analyte. Quantitative evaluation of hotspots was presented using spatially resolved Raman mapping of graphene SERS enhancement. Graphene plays a crucial role in quantifying SERS hotspots and paves the path for defining SERS EF that could be universally applied to various SERS systems. A reproducible and statistically

  20. Windows Azure Platform

    CERN Document Server

    Redkar, Tejaswi

    2011-01-01

    The Windows Azure Platform has rapidly established itself as one of the most sophisticated cloud computing platforms available. With Microsoft working to continually update their product and keep it at the cutting edge, the future looks bright - if you have the skills to harness it. In particular, new features such as remote desktop access, dynamic content caching and secure content delivery using SSL make the latest version of Azure a more powerful solution than ever before. It's widely agreed that cloud computing has produced a paradigm shift in traditional architectural concepts by providin