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Sample records for research platform sarrp

  1. A high resolution small animal radiation research platform (SARRP) with x-ray tomographic guidance capabilities

    Science.gov (United States)

    Wong, John; Armour, Elwood; Kazanzides, Peter; Iordachita, Iulian; Tryggestad, Erik; Deng, Hua; Matinfar, Mohammad; Kennedy, Christopher; Liu, Zejian; Chan, Timothy; Gray, Owen; Verhaegen, Frank; McNutt, Todd; Ford, Eric; DeWeese, Theodore L.

    2008-01-01

    Purpose To demonstrate the CT imaging, conformal irradiation and treatment planning capabilities of a small animal radiation research platform (SARRP). Methods The SARRP employs a dual-focal spot, constant voltage x-ray source mounted on a gantry with a source-to-isocenter distance of 35 cm. Gantry rotation is limited to 120° from vertical. Eighty to 100 kVp x-rays from the smaller 0.4 mm focal spot are used for imaging. Both 0.4 mm and 3.0 mm focal spots operate at 225 kVp for irradiation. Robotic translate/rotate stages are used to position the animal. Cone-beam (CB) CT imaging is achieved by rotating the horizontal animal between the stationary x-ray source and a flat-panel detector. Radiation beams range from 0.5 mm in diameter to (60 × 60) mm2. Dosimetry is measured with radio-chromic films. Monte Carlo dose calculations are employed for treatment planning. The combination of gantry and robotic stage motions facilitate conformal irradiation. Results The SARRP spans 3 ft × 4 ft × 6 ft (WxLxH). Depending on filtration, the isocenter dose outputs at 1 cm depth in water range from 22 to 375 cGy/min from the smallest to the largest radiation fields. The 20% to 80% dose fall-off spans 0.16 mm. CBCT with (0.6 × 0.6 × 0.6) mm3 voxel resolution is acquired with less than 1 cGy. Treatment planning is performed at sub-mm resolution. Conclusions The capability of the SARRP to deliver highly focal beams to multiple animal model systems provides new research opportunities that more realistically bridge laboratory research and clinical translation. PMID:18640502

  2. MOSFET assessment of radiation dose delivered to mice using the Small Animal Radiation Research Platform (SARRP).

    Science.gov (United States)

    Ngwa, Wilfred; Korideck, Houari; Chin, Lee M; Makrigiorgos, G Mike; Berbeco, Ross I

    2011-12-01

    The Small Animal Radiation Research Platform (SARRP) is a novel isocentric irradiation system that enables state-of-the-art image-guided radiotherapy research to be performed with animal models. This paper reports the results obtained from investigations assessing the radiation dose delivered by the SARRP to different anatomical target volumes in mice. Surgically implanted metal oxide semiconductor field effect transistors (MOSFET) dosimeters were employed for the dose assessment. The results reveal differences between the calculated and measured dose of -3.5 to 0.5%, -5.2 to -0.7%, -3.9 to 0.5%, -5.9 to 2.5%, -5.5 to 0.5%, and -4.3 to 0% for the left kidney, liver, pancreas, prostate, left lung, and brain, respectively. Overall, the findings show less than 6% difference between the delivered and calculated dose, without tissue heterogeneity corrections. These results provide a useful assessment of the need for tissue heterogeneity corrections in SARRP dose calculations for clinically relevant tumor model sites.

  3. WE-EF-BRA-01: A Dual-Use Optical Tomography System for Small Animal Radiation Research Platform (SARRP)

    Energy Technology Data Exchange (ETDEWEB)

    Wang, K; Bin, Z; Wong, J [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Hospital, Baltimore, MD (United States); He, X; Iordachita, I [Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD (United States)

    2015-06-15

    Purpose: We develop a novel dual-use configuration for a tri-modality, CBCT/bioluminescence tomography(BLT)/fluorescence tomography(FT), imaging system with the SARRP that can function as a standalone system for longitudinal imaging research and on-board the SARRP to guide irradiation. BLT provides radiation guidance for soft tissue target, while FT offers functional information allowing mechanistic investigations. Methods: The optical assembly includes CCD camera, lens, filter wheel, 3-way mirrors, scanning fiber system and light-tight enclosure. The rotating mirror system directs the optical signal from the animal surface to the camera at multiple projection over 180 degree. The fiber-laser system serves as the external light source for the FT application. Multiple filters are used for multispectral imaging to enhance localization accuracy using BLT. SARRP CBCT provides anatomical information and geometric mesh for BLT/FT reconstruction. To facilitate dual use, the 3-way mirror system is cantilevered in front of the camera. The entire optical assembly is driven by a 1D linear stage to dock onto an independent mouse support bed for standalone application. After completion of on-board optical imaging, the system is retracted from the SARRP to allow irradiation of the mouse. Results: A tissue-simulating phantom and a mouse model with a luminescence light source are used to demonstrate the function of the dual-use optical system. Feasibility data have been obtained based on a manual-docking prototype. The center of mass of light source determined in living mouse with on-board BLT is within 1±0.2mm of that with CBCT. The performance of the motorized system is expected to be the same and will be presented. Conclusion: We anticipate the motorized dual use system provide significant efficiency gain over our manual docking and off-line system. By also supporting off-line longitudinal studies independent of the SARRP, the dual-use system is a highly efficient and cost

  4. Development and implementation of EPID-based quality assurance tests for the small animal radiation research platform (SARRP).

    Science.gov (United States)

    Anvari, Akbar; Poirier, Yannick; Sawant, Amit

    2018-04-28

    Although small animal image-guided radiotherapy (SA-IGRT) systems are used increasingly in preclinical research, tools for performing routine quality assurance (QA) have not been optimized and are not readily available. Robust, efficient, and reliable QA tools are needed to ensure the accuracy and reproducibility of SA-IGRT systems. Several investigators have reported custom-made phantoms and protocols for SA-IGRT systems QA. These are typically time and resource intensive and are therefore not well suited to the preclinical radiotherapy environment, in which physics support is limited and routine QA is performed by technical staff. We investigated the use of the inbuilt electronic portal imaging device (EPID) to develop and validate routine QA tests and procedures. In this work, we focus on the Xstrahl Small Animal Radiation Research Platform (SARRP) EPID. However, the methodology and tests developed here are applicable to any SA-IGRT system that incorporates an EPID. We performed a comprehensive characterization of the dosimetric properties of the camera-based EPID at kilovoltage energies over a 11-month period, including detector warm-up time, radiation dose history effect, stability and short- and long-term reproducibility, gantry angle dependency, output factor, and linearity of the EPID response. We developed a test to measure the constancy of beam quality in terms of half-value layer and tube peak potential using the EPID. We verified the SARRP daily output and beam profile constancy using the imager. We investigated the use of the imager to monitor beam-targeting accuracy at various gantry and couch angles. The EPID response was stable and reproducible, exhibiting maximum variations of ≤0.3% and ≤1.9% for short and long terms, respectively. The detector showed no dependence on response at different gantry angles, with a maximum variation ≤0.5%. We found close agreement in output factor measurement between the portal imager and reference dosimeters

  5. MRI-Only Based Radiotherapy Treatment Planning for the Rat Brain on a Small Animal Radiation Research Platform (SARRP.

    Directory of Open Access Journals (Sweden)

    Shandra Gutierrez

    Full Text Available Computed tomography (CT is the standard imaging modality in radiation therapy treatment planning (RTP. However, magnetic resonance (MR imaging provides superior soft tissue contrast, increasing the precision of target volume selection. We present MR-only based RTP for a rat brain on a small animal radiation research platform (SARRP using probabilistic voxel classification with multiple MR sequences. Six rat heads were imaged, each with one CT and five MR sequences. The MR sequences were: T1-weighted, T2-weighted, zero-echo time (ZTE, and two ultra-short echo time sequences with 20 μs (UTE1 and 2 ms (UTE2 echo times. CT data were manually segmented into air, soft tissue, and bone to obtain the RTP reference. Bias field corrected MR images were automatically segmented into the same tissue classes using a fuzzy c-means segmentation algorithm with multiple images as input. Similarities between segmented CT and automatic segmented MR (ASMR images were evaluated using Dice coefficient. Three ASMR images with high similarity index were used for further RTP. Three beam arrangements were investigated. Dose distributions were compared by analysing dose volume histograms. The highest Dice coefficients were obtained for the ZTE-UTE2 combination and for the T1-UTE1-T2 combination when ZTE was unavailable. Both combinations, along with UTE1-UTE2, often used to generate ASMR images, were used for further RTP. Using 1 beam, MR based RTP underestimated the dose to be delivered to the target (range: 1.4%-7.6%. When more complex beam configurations were used, the calculated dose using the ZTE-UTE2 combination was the most accurate, with 0.7% deviation from CT, compared to 0.8% for T1-UTE1-T2 and 1.7% for UTE1-UTE2. The presented MR-only based workflow for RTP on a SARRP enables both accurate organ delineation and dose calculations using multiple MR sequences. This method can be useful in longitudinal studies where CT's cumulative radiation dose might contribute

  6. MRI-Only Based Radiotherapy Treatment Planning for the Rat Brain on a Small Animal Radiation Research Platform (SARRP).

    Science.gov (United States)

    Gutierrez, Shandra; Descamps, Benedicte; Vanhove, Christian

    2015-01-01

    Computed tomography (CT) is the standard imaging modality in radiation therapy treatment planning (RTP). However, magnetic resonance (MR) imaging provides superior soft tissue contrast, increasing the precision of target volume selection. We present MR-only based RTP for a rat brain on a small animal radiation research platform (SARRP) using probabilistic voxel classification with multiple MR sequences. Six rat heads were imaged, each with one CT and five MR sequences. The MR sequences were: T1-weighted, T2-weighted, zero-echo time (ZTE), and two ultra-short echo time sequences with 20 μs (UTE1) and 2 ms (UTE2) echo times. CT data were manually segmented into air, soft tissue, and bone to obtain the RTP reference. Bias field corrected MR images were automatically segmented into the same tissue classes using a fuzzy c-means segmentation algorithm with multiple images as input. Similarities between segmented CT and automatic segmented MR (ASMR) images were evaluated using Dice coefficient. Three ASMR images with high similarity index were used for further RTP. Three beam arrangements were investigated. Dose distributions were compared by analysing dose volume histograms. The highest Dice coefficients were obtained for the ZTE-UTE2 combination and for the T1-UTE1-T2 combination when ZTE was unavailable. Both combinations, along with UTE1-UTE2, often used to generate ASMR images, were used for further RTP. Using 1 beam, MR based RTP underestimated the dose to be delivered to the target (range: 1.4%-7.6%). When more complex beam configurations were used, the calculated dose using the ZTE-UTE2 combination was the most accurate, with 0.7% deviation from CT, compared to 0.8% for T1-UTE1-T2 and 1.7% for UTE1-UTE2. The presented MR-only based workflow for RTP on a SARRP enables both accurate organ delineation and dose calculations using multiple MR sequences. This method can be useful in longitudinal studies where CT's cumulative radiation dose might contribute to the total

  7. The small-animal radiation research platform (SARRP): dosimetry of a focused lens system

    Energy Technology Data Exchange (ETDEWEB)

    Deng Hua [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Kennedy, Christopher W [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Armour, Elwood [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Tryggestad, Erik [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Ford, Eric [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); McNutt, Todd [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Jiang Licai [OSMIC Inc., 1900 Taylor Rd., Auburn Hills, MI (United States); Wong, John [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States)

    2007-05-21

    A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min{sup -1} at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of {+-}5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD.

  8. The small-animal radiation research platform (SARRP): dosimetry of a focused lens system.

    Science.gov (United States)

    Deng, Hua; Kennedy, Christopher W; Armour, Elwood; Tryggestad, Erik; Ford, Eric; McNutt, Todd; Jiang, Licai; Wong, John

    2007-05-21

    A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min(-1) at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of +/-5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD.

  9. The small-animal radiation research platform (SARRP): dosimetry of a focused lens system

    International Nuclear Information System (INIS)

    Deng Hua; Kennedy, Christopher W; Armour, Elwood; Tryggestad, Erik; Ford, Eric; McNutt, Todd; Jiang Licai; Wong, John

    2007-01-01

    A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min -1 at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of ±5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD

  10. TH-C-17A-12: Integrated CBCT and Optical Tomography System On-Board a Small Animal Radiation Research Platform (SARRP)

    Energy Technology Data Exchange (ETDEWEB)

    Wang, K; Zhang, B; Eslami, S; Iordachita, I; Wong, J [Johns Hopkins University, Baltimore, MD (United States); Patterson, M [Hamilton Regional Cancer Ctr., Hamilton, ON (Canada)

    2014-06-15

    Purpose: We present a newly developed on-board optical tomography system for SARRP. Innovative features include the compact design and fast acquisition optical method to perform 3D soft tissue radiation guidance. Because of the on-board feature and the combination of the CBCT, diffusive optical tomography (DOT), bioluminescence and fluorescence tomography (BLT and FT), this integrated system is expected to provide more accurate soft tissue guidance than an off-line system as well as highly sensitive functional imaging in preclinical research. Methods: Images are acquired in the order of CBCT, DOT and then BLT/FT, where the SARRP CBCT and DOT are used to provide the anatomical and optical properties information to enhance the subsequent BLT/FT optical reconstruction. The SARRP stage is redesigned to include 9 imbedded optical fibers in contact with the animal's skin. These fibers, connected to a white light lamp or laser, serve as the light sources for the DOT or FT, respectively. A CCD camera with f/1.4 lens and multi-spectral filter set is used as the optical detector and is mounted on a portable cart ready to dock into the SARRP. No radiation is delivered during optical image acquisition. A 3-way mirror system capable of 180 degree rotation around the animal reflects the optical signal to the camera at multiple projection angles. A special black-painted dome covers the stage and provides the light shielding. Results: Spontaneous metastatic bioluminescent liver and lung tumor models will be used to validate the 3D BLT reconstruction. To demonstrate the capability of our FT system, GastroSense750 fluorescence agent will be used to imaging the mouse stomach and intestinal region in 3D. Conclusion: We expect that this integrated CBCT and optical tomography on-board a SARRP will present new research opportunities for pre-clinical radiation research. Supported by NCI RO1-CA 158100.

  11. TH-C-17A-12: Integrated CBCT and Optical Tomography System On-Board a Small Animal Radiation Research Platform (SARRP)

    International Nuclear Information System (INIS)

    Wang, K; Zhang, B; Eslami, S; Iordachita, I; Wong, J; Patterson, M

    2014-01-01

    Purpose: We present a newly developed on-board optical tomography system for SARRP. Innovative features include the compact design and fast acquisition optical method to perform 3D soft tissue radiation guidance. Because of the on-board feature and the combination of the CBCT, diffusive optical tomography (DOT), bioluminescence and fluorescence tomography (BLT and FT), this integrated system is expected to provide more accurate soft tissue guidance than an off-line system as well as highly sensitive functional imaging in preclinical research. Methods: Images are acquired in the order of CBCT, DOT and then BLT/FT, where the SARRP CBCT and DOT are used to provide the anatomical and optical properties information to enhance the subsequent BLT/FT optical reconstruction. The SARRP stage is redesigned to include 9 imbedded optical fibers in contact with the animal's skin. These fibers, connected to a white light lamp or laser, serve as the light sources for the DOT or FT, respectively. A CCD camera with f/1.4 lens and multi-spectral filter set is used as the optical detector and is mounted on a portable cart ready to dock into the SARRP. No radiation is delivered during optical image acquisition. A 3-way mirror system capable of 180 degree rotation around the animal reflects the optical signal to the camera at multiple projection angles. A special black-painted dome covers the stage and provides the light shielding. Results: Spontaneous metastatic bioluminescent liver and lung tumor models will be used to validate the 3D BLT reconstruction. To demonstrate the capability of our FT system, GastroSense750 fluorescence agent will be used to imaging the mouse stomach and intestinal region in 3D. Conclusion: We expect that this integrated CBCT and optical tomography on-board a SARRP will present new research opportunities for pre-clinical radiation research. Supported by NCI RO1-CA 158100

  12. SU-E-T-89: Comprehensive Quality Assurance Phantom for the Small Animal Radiation Research Platform

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    Jermoumi, M; Ngwa, W [University of Massachusetts Lowell, MA (United States); Dana-Farber Cancer Institute, Brigham and Women' s Hospital, Harvard Medical School, Boston, MA (United States); Korideck, H; Zygmanski, P; Berbeco, R; Makrigiorgos, G; Cormack, R [Dana-Farber Cancer Institute, Brigham and Women' s Hospital, Harvard Medical School, Boston, MA (United States)

    2014-06-01

    Purpose: Use of Small Animal Radiation Research Platform (SARRP) systems for conducting state-of-the-art image guided radiotherapy (IGRT) research on small animals has become more common over the past years. The purpose of this work is to develop and test the suitability and performance of a comprehensive quality assurance (QA) phantom for the SARRP. Methods: A QA phantom was developed for carrying out daily, monthly and annual QA tasks including imaging, dosimetry and treatment planning system (TPS) performance evaluation of the SARRP. The QA phantom consists of nine (60×60×5 mm3) KV-energy tissue equivalent solid water slabs that can be employed for annual dosimetry QA with film. Three of the top slabs are replaceable with ones incorporating Mosfets or OSLDs arranged in a quincunx pattern, or a slab drilled to accommodate an ion chamber insert. These top slabs are designed to facilitate routine daily and monthly QA tasks such as output constancy, isocenter congruency test, treatment planning system (TPS) QA, etc. One slab is designed with inserts for image QA. A prototype of the phantom was applied to test the performance of the imaging, planning and treatment delivery systems. Results: Output constancy test results showed daily variations within 3%. For isocenter congruency test, the phantom could be used to detect 0.3 mm deviations of the CBCT isocenter from the radiation isocenter. Using the Mosfet in phantom as target, the difference between TPS calculations and measurements was within 5%. Image-quality parameters could also be assessed in terms of geometric accuracy, CT number accuracy, linearity, noise and image uniformity, etc. Conclusion: The developed phantom can be employed as a simple tool for comprehensive performance evaluation of the SARRP. The study provides a reference for development of a comprehensive quality assurance program for the SARRP, with proposed tolerances and frequency of required tests.

  13. SU-E-T-89: Comprehensive Quality Assurance Phantom for the Small Animal Radiation Research Platform

    International Nuclear Information System (INIS)

    Jermoumi, M; Ngwa, W; Korideck, H; Zygmanski, P; Berbeco, R; Makrigiorgos, G; Cormack, R

    2014-01-01

    Purpose: Use of Small Animal Radiation Research Platform (SARRP) systems for conducting state-of-the-art image guided radiotherapy (IGRT) research on small animals has become more common over the past years. The purpose of this work is to develop and test the suitability and performance of a comprehensive quality assurance (QA) phantom for the SARRP. Methods: A QA phantom was developed for carrying out daily, monthly and annual QA tasks including imaging, dosimetry and treatment planning system (TPS) performance evaluation of the SARRP. The QA phantom consists of nine (60×60×5 mm3) KV-energy tissue equivalent solid water slabs that can be employed for annual dosimetry QA with film. Three of the top slabs are replaceable with ones incorporating Mosfets or OSLDs arranged in a quincunx pattern, or a slab drilled to accommodate an ion chamber insert. These top slabs are designed to facilitate routine daily and monthly QA tasks such as output constancy, isocenter congruency test, treatment planning system (TPS) QA, etc. One slab is designed with inserts for image QA. A prototype of the phantom was applied to test the performance of the imaging, planning and treatment delivery systems. Results: Output constancy test results showed daily variations within 3%. For isocenter congruency test, the phantom could be used to detect 0.3 mm deviations of the CBCT isocenter from the radiation isocenter. Using the Mosfet in phantom as target, the difference between TPS calculations and measurements was within 5%. Image-quality parameters could also be assessed in terms of geometric accuracy, CT number accuracy, linearity, noise and image uniformity, etc. Conclusion: The developed phantom can be employed as a simple tool for comprehensive performance evaluation of the SARRP. The study provides a reference for development of a comprehensive quality assurance program for the SARRP, with proposed tolerances and frequency of required tests

  14. A comprehensive system for dosimetric commissioning and Monte Carlo validation for the small animal radiation research platform.

    Science.gov (United States)

    Tryggestad, E; Armour, M; Iordachita, I; Verhaegen, F; Wong, J W

    2009-09-07

    Our group has constructed the small animal radiation research platform (SARRP) for delivering focal, kilo-voltage radiation to targets in small animals under robotic control using cone-beam CT guidance. The present work was undertaken to support the SARRP's treatment planning capabilities. We have devised a comprehensive system for characterizing the radiation dosimetry in water for the SARRP and have developed a Monte Carlo dose engine with the intent of reproducing these measured results. We find that the SARRP provides sufficient therapeutic dose rates ranging from 102 to 228 cGy min(-1) at 1 cm depth for the available set of high-precision beams ranging from 0.5 to 5 mm in size. In terms of depth-dose, the mean of the absolute percentage differences between the Monte Carlo calculations and measurement is 3.4% over the full range of sampled depths spanning 0.5-7.2 cm for the 3 and 5 mm beams. The measured and computed profiles for these beams agree well overall; of note, good agreement is observed in the profile tails. Especially for the smallest 0.5 and 1 mm beams, including a more realistic description of the effective x-ray source into the Monte Carlo model may be important.

  15. A comprehensive system for dosimetric commissioning and Monte Carlo validation for the small animal radiation research platform

    Energy Technology Data Exchange (ETDEWEB)

    Tryggestad, E; Armour, M; Wong, J W [Deptartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, MD (United States); Iordachita, I [Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD (United States); Verhaegen, F [Department of Radiation Oncology (MAASTRO Physics), GROW School, Maastricht University Medical Center, Maastricht (Netherlands)

    2009-09-07

    Our group has constructed the small animal radiation research platform (SARRP) for delivering focal, kilo-voltage radiation to targets in small animals under robotic control using cone-beam CT guidance. The present work was undertaken to support the SARRP's treatment planning capabilities. We have devised a comprehensive system for characterizing the radiation dosimetry in water for the SARRP and have developed a Monte Carlo dose engine with the intent of reproducing these measured results. We find that the SARRP provides sufficient therapeutic dose rates ranging from 102 to 228 cGy min{sup -1} at 1 cm depth for the available set of high-precision beams ranging from 0.5 to 5 mm in size. In terms of depth-dose, the mean of the absolute percentage differences between the Monte Carlo calculations and measurement is 3.4% over the full range of sampled depths spanning 0.5-7.2 cm for the 3 and 5 mm beams. The measured and computed profiles for these beams agree well overall; of note, good agreement is observed in the profile tails. Especially for the smallest 0.5 and 1 mm beams, including a more realistic description of the effective x-ray source into the Monte Carlo model may be important.

  16. Image-guided small animal radiation research platform: calibration of treatment beam alignment

    International Nuclear Information System (INIS)

    Matinfar, Mohammad; Iordachita, Iulian; Kazanzides, Peter; Ford, Eric; Wong, John

    2009-01-01

    Small animal research allows detailed study of biological processes, disease progression and response to therapy with the potential to provide a natural bridge to the clinical environment. The small animal radiation research platform (SARRP) is a portable system for precision irradiation with beam sizes down to approximately 0.5 mm and optimally planned radiation with on-board cone-beam CT (CBCT) guidance. This paper focuses on the geometric calibration of the system for high-precision irradiation. A novel technique for the calibration of the treatment beam is presented, which employs an x-ray camera whose precise positioning need not be known. Using the camera system we acquired a digitally reconstructed 3D 'star shot' for gantry calibration and then developed a technique to align each beam to a common isocenter with the robotic animal positioning stages. The calibration incorporates localization by cone-beam CT guidance. Uncorrected offsets of the beams with respect to the calibration origin ranged from 0.4 mm to 5.2 mm. With corrections, these alignment errors can be reduced to the sub-millimeter range. The calibration technique was used to deliver a stereotactic-like arc treatment to a phantom constructed with EBT Gafchromic films. All beams were shown to intersect at a common isocenter with a measured beam (FWHM) of approximately 1.07 mm using the 0.5 mm collimated beam. The desired positioning accuracy of the SARRP is 0.25 mm and the results indicate an accuracy of 0.2 mm. To fully realize the radiation localization capabilities of the SARRP, precise geometric calibration is required, as with any such system. The x-ray camera-based technique presented here provides a straightforward and semi-automatic method for system calibration.

  17. The COMET Sleep Research Platform.

    Science.gov (United States)

    Nichols, Deborah A; DeSalvo, Steven; Miller, Richard A; Jónsson, Darrell; Griffin, Kara S; Hyde, Pamela R; Walsh, James K; Kushida, Clete A

    2014-01-01

    The Comparative Outcomes Management with Electronic Data Technology (COMET) platform is extensible and designed for facilitating multicenter electronic clinical research. Our research goals were the following: (1) to conduct a comparative effectiveness trial (CET) for two obstructive sleep apnea treatments-positive airway pressure versus oral appliance therapy; and (2) to establish a new electronic network infrastructure that would support this study and other clinical research studies. The COMET platform was created to satisfy the needs of CET with a focus on creating a platform that provides comprehensive toolsets, multisite collaboration, and end-to-end data management. The platform also provides medical researchers the ability to visualize and interpret data using business intelligence (BI) tools. COMET is a research platform that is scalable and extensible, and which, in a future version, can accommodate big data sets and enable efficient and effective research across multiple studies and medical specialties. The COMET platform components were designed for an eventual move to a cloud computing infrastructure that enhances sustainability, overall cost effectiveness, and return on investment.

  18. Small animal radiotherapy research platforms

    Energy Technology Data Exchange (ETDEWEB)

    Verhaegen, Frank; Granton, Patrick [Department of Radiation Oncology (MAASTRO), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht 6201 BN (Netherlands); Tryggestad, Erik, E-mail: frank.verhaegen@maastro.nl [Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21231 (United States)

    2011-06-21

    Advances in conformal radiation therapy and advancements in pre-clinical radiotherapy research have recently stimulated the development of precise micro-irradiators for small animals such as mice and rats. These devices are often kilovolt x-ray radiation sources combined with high-resolution CT imaging equipment for image guidance, as the latter allows precise and accurate beam positioning. This is similar to modern human radiotherapy practice. These devices are considered a major step forward compared to the current standard of animal experimentation in cancer radiobiology research. The availability of this novel equipment enables a wide variety of pre-clinical experiments on the synergy of radiation with other therapies, complex radiation schemes, sub-target boost studies, hypofractionated radiotherapy, contrast-enhanced radiotherapy and studies of relative biological effectiveness, to name just a few examples. In this review we discuss the required irradiation and imaging capabilities of small animal radiation research platforms. We describe the need for improved small animal radiotherapy research and highlight pioneering efforts, some of which led recently to commercially available prototypes. From this, it will be clear that much further development is still needed, on both the irradiation side and imaging side. We discuss at length the need for improved treatment planning tools for small animal platforms, and the current lack of a standard therein. Finally, we mention some recent experimental work using the early animal radiation research platforms, and the potential they offer for advancing radiobiology research. (topical review)

  19. Small animal radiotherapy research platforms

    Science.gov (United States)

    Verhaegen, Frank; Granton, Patrick; Tryggestad, Erik

    2011-06-01

    Advances in conformal radiation therapy and advancements in pre-clinical radiotherapy research have recently stimulated the development of precise micro-irradiators for small animals such as mice and rats. These devices are often kilovolt x-ray radiation sources combined with high-resolution CT imaging equipment for image guidance, as the latter allows precise and accurate beam positioning. This is similar to modern human radiotherapy practice. These devices are considered a major step forward compared to the current standard of animal experimentation in cancer radiobiology research. The availability of this novel equipment enables a wide variety of pre-clinical experiments on the synergy of radiation with other therapies, complex radiation schemes, sub-target boost studies, hypofractionated radiotherapy, contrast-enhanced radiotherapy and studies of relative biological effectiveness, to name just a few examples. In this review we discuss the required irradiation and imaging capabilities of small animal radiation research platforms. We describe the need for improved small animal radiotherapy research and highlight pioneering efforts, some of which led recently to commercially available prototypes. From this, it will be clear that much further development is still needed, on both the irradiation side and imaging side. We discuss at length the need for improved treatment planning tools for small animal platforms, and the current lack of a standard therein. Finally, we mention some recent experimental work using the early animal radiation research platforms, and the potential they offer for advancing radiobiology research.

  20. Small animal radiotherapy research platforms

    International Nuclear Information System (INIS)

    Verhaegen, Frank; Granton, Patrick; Tryggestad, Erik

    2011-01-01

    Advances in conformal radiation therapy and advancements in pre-clinical radiotherapy research have recently stimulated the development of precise micro-irradiators for small animals such as mice and rats. These devices are often kilovolt x-ray radiation sources combined with high-resolution CT imaging equipment for image guidance, as the latter allows precise and accurate beam positioning. This is similar to modern human radiotherapy practice. These devices are considered a major step forward compared to the current standard of animal experimentation in cancer radiobiology research. The availability of this novel equipment enables a wide variety of pre-clinical experiments on the synergy of radiation with other therapies, complex radiation schemes, sub-target boost studies, hypofractionated radiotherapy, contrast-enhanced radiotherapy and studies of relative biological effectiveness, to name just a few examples. In this review we discuss the required irradiation and imaging capabilities of small animal radiation research platforms. We describe the need for improved small animal radiotherapy research and highlight pioneering efforts, some of which led recently to commercially available prototypes. From this, it will be clear that much further development is still needed, on both the irradiation side and imaging side. We discuss at length the need for improved treatment planning tools for small animal platforms, and the current lack of a standard therein. Finally, we mention some recent experimental work using the early animal radiation research platforms, and the potential they offer for advancing radiobiology research. (topical review)

  1. Creating a platform for collaborative genomic research

    Directory of Open Access Journals (Sweden)

    Mark Smithson

    2017-04-01

    The developed genomics informatics platform provides a step-change in this type of genetic research, accelerating reproducible collaborative research across multiple disparate organisations and data sources, of varying type and complexity.

  2. Reconcile: A Coreference Resolution Research Platform

    Energy Technology Data Exchange (ETDEWEB)

    Stoyanov, V; Cardie, C; Gilbert, N; Riloff, E; Buttler, D; Hysom, D

    2009-10-29

    Despite the availability of standard data sets and metrics, approaches to the problem of noun phrase coreference resolution are hard to compare empirically due to the different evaluation setting stemming, in part, from the lack of comprehensive coreference resolution research platforms. In this tech report we present Reconcile, a coreference resolution research platform that aims to facilitate the implementation of new approaches to coreference resolution as well as the comparison of existing approaches. We discuss Reconcile's architecture and give results of running Reconcile on six data sets using four evaluation metrics, showing that Reconcile's performance is comparable to state-of-the-art systems in coreference resolution.

  3. Researching intimacy through social media: A cross-platform approach

    OpenAIRE

    Miguel, C

    2016-01-01

    This paper aims to contribute to the understanding of how to study the way people build intimacy and manage privacy through social media interaction. It explores the research design and methodology of a research project based on a multi-sited case study composed of three different social media platforms: Badoo, CouchSurfing, and Facebook. This cross-platform approach is useful to observe how intimacy is often negotiated across different platforms. The research project focuses on the cities of...

  4. Research and application of mobile teaching platform

    Science.gov (United States)

    Yang, Ping; Xue, Hongjiao

    2017-08-01

    The application of mobile technology in university digital campus is ripe. This article mainly introduced the necessity of teaching platform based on mobile Internet in the teaching of higher vocational education, and the key to the construction of the feasibility of mobile learning platform, which is a feasible and effective teaching model under the new situation, worthy of promotion. The design and application of teaching platform based on mobile Internet is the change of educational ideas and working methods, and is the new starting point of Higher Vocational education.

  5. Research and development of common DAQ platform

    International Nuclear Information System (INIS)

    Higuchi, T.; Igarashi, Y.; Nakao, M.; Suzuki, S.Y.; Tanaka, M.; Nagasaka, Y.; Varner, G.

    2003-01-01

    The upgrade of the KEKB accelerator toward L=10 35 cm -2 s -1 requires an upgrade of the Belle data acquisition system. To match the market trend, we develop a DAQ platform based on the PCI bus that enables fastest DAQ with longer lifetime of the system. The platform is a VME-9U motherboard comprising of four slots for signal digitization modules and three PMC slots to house CPU for data compression. The platform is equipped with event FIFOs for data buffering to minimize the dead-time. A trigger module residing on VME-6U size rear board is connected to the 9U board via PCI-PCI bridge to make an interrupt for the CPU upon the level-1 trigger. (author)

  6. Platforms.

    Science.gov (United States)

    Josko, Deborah

    2014-01-01

    The advent of DNA sequencing technologies and the various applications that can be performed will have a dramatic effect on medicine and healthcare in the near future. There are several DNA sequencing platforms available on the market for research and clinical use. Based on the medical laboratory scientist or researcher's needs and taking into consideration laboratory space and budget, one can chose which platform will be beneficial to their institution and their patient population. Although some of the instrument costs seem high, diagnosing a patient quickly and accurately will save hospitals money with fewer hospital stays and targeted treatment based on an individual's genetic make-up. By determining the type of disease an individual has, based on the mutations present or having the ability to prescribe the appropriate antimicrobials based on the knowledge of the organism's resistance patterns, the clinician will be better able to treat and diagnose a patient which ultimately will improve patient outcomes and prognosis.

  7. Multi-donor Research Platform on Social Protection, Financial ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Multi-donor Research Platform on Social Protection, Financial Inclusion and ICTs ... been some experiments linking a financial inclusion component to CCT programs, ... Institution. Universidad de Chile. Pays d' institution. Chile. Site internet.

  8. Multi-donor Research Platform on Social Protection, Financial ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Multi-donor Research Platform on Social Protection, Financial Inclusion and ... There have been some experiments linking a financial inclusion component to CCT programs, ... Universidad de Chile. Institution Country. Chile. Institution Website.

  9. IT Governance Research and Collaborative Platform

    Directory of Open Access Journals (Sweden)

    Carsten Mueller

    2015-01-01

    Full Text Available SPSPR (S-Strategy, P-Business Processes, S-ICT Services, P-ICT Processes, R-ICT Resources is a layered framework that is used to represent the relationship between business management and ICT management in the context of cloud computing. This research article applies the advanced object-oriented techniques and develops a fundamental object-oriented SPSPR-Model including four basic design patterns layer, dynamic factory, role and session.

  10. Researching intimacy through social media: A cross-platform approach

    Directory of Open Access Journals (Sweden)

    Cristina Miguel

    2016-06-01

    Full Text Available This paper aims to contribute to the understanding of how to study the way people build intimacy and manage privacy through social media interaction. It explores the research design and methodology of a research project based on a multi-sited case study composed of three different social media platforms: Badoo, CouchSurfing, and Facebook. This cross-platform approach is useful to observe how intimacy is often negotiated across different platforms. The research project focuses on the cities of Leeds (UK and Barcelona (Spain. In particular, this article discusses the methods used to recruit participants and collect data for that study - namely, participant observation, semi-structured interviews, and user profiles analysis. This cross-platform approach and multi-method research design is helpful to investigate the nature of intimacy practices facilitated by social media at several levels: online/offline, across different platforms, among different types of relationships, within both new and existing relationships, and in different locations

  11. Bioluminescence Tomography–Guided Radiation Therapy for Preclinical Research

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Bin [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland (United States); Wang, Ken Kang-Hsin, E-mail: kwang27@jhmi.edu [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland (United States); Yu, Jingjing [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland (United States); School of Physics and Information Technology, Shaanxi Normal University, Shaanxi (China); Eslami, Sohrab; Iordachita, Iulian [Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, Maryland (United States); Reyes, Juvenal; Malek, Reem [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland (United States); Tran, Phuoc T. [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland (United States); Department of Oncology and Urology, Brady Urological Institute, Johns Hopkins University, Baltimore, Maryland (United States); Patterson, Michael S. [Department of Medical Physics and Applied Radiation Sciences, McMaster University, Hamilton, Ontario (Canada); Wong, John W. [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland (United States)

    2016-04-01

    Purpose: In preclinical radiation research, it is challenging to localize soft tissue targets based on cone beam computed tomography (CBCT) guidance. As a more effective method to localize soft tissue targets, we developed an online bioluminescence tomography (BLT) system for small-animal radiation research platform (SARRP). We demonstrated BLT-guided radiation therapy and validated targeting accuracy based on a newly developed reconstruction algorithm. Methods and Materials: The BLT system was designed to dock with the SARRP for image acquisition and to be detached before radiation delivery. A 3-mirror system was devised to reflect the bioluminescence emitted from the subject to a stationary charge-coupled device (CCD) camera. Multispectral BLT and the incomplete variables truncated conjugate gradient method with a permissible region shrinking strategy were used as the optimization scheme to reconstruct bioluminescent source distributions. To validate BLT targeting accuracy, a small cylindrical light source with high CBCT contrast was placed in a phantom and also in the abdomen of a mouse carcass. The center of mass (CoM) of the source was recovered from BLT and used to guide radiation delivery. The accuracy of the BLT-guided targeting was validated with films and compared with the CBCT-guided delivery. In vivo experiments were conducted to demonstrate BLT localization capability for various source geometries. Results: Online BLT was able to recover the CoM of the embedded light source with an average accuracy of 1 mm compared to that with CBCT localization. Differences between BLT- and CBCT-guided irradiation shown on the films were consistent with the source localization revealed in the BLT and CBCT images. In vivo results demonstrated that our BLT system could potentially be applied for multiple targets and tumors. Conclusions: The online BLT/CBCT/SARRP system provides an effective solution for soft tissue targeting, particularly for small, nonpalpable, or

  12. Bioluminescence Tomography–Guided Radiation Therapy for Preclinical Research

    International Nuclear Information System (INIS)

    Zhang, Bin; Wang, Ken Kang-Hsin; Yu, Jingjing; Eslami, Sohrab; Iordachita, Iulian; Reyes, Juvenal; Malek, Reem; Tran, Phuoc T.; Patterson, Michael S.; Wong, John W.

    2016-01-01

    Purpose: In preclinical radiation research, it is challenging to localize soft tissue targets based on cone beam computed tomography (CBCT) guidance. As a more effective method to localize soft tissue targets, we developed an online bioluminescence tomography (BLT) system for small-animal radiation research platform (SARRP). We demonstrated BLT-guided radiation therapy and validated targeting accuracy based on a newly developed reconstruction algorithm. Methods and Materials: The BLT system was designed to dock with the SARRP for image acquisition and to be detached before radiation delivery. A 3-mirror system was devised to reflect the bioluminescence emitted from the subject to a stationary charge-coupled device (CCD) camera. Multispectral BLT and the incomplete variables truncated conjugate gradient method with a permissible region shrinking strategy were used as the optimization scheme to reconstruct bioluminescent source distributions. To validate BLT targeting accuracy, a small cylindrical light source with high CBCT contrast was placed in a phantom and also in the abdomen of a mouse carcass. The center of mass (CoM) of the source was recovered from BLT and used to guide radiation delivery. The accuracy of the BLT-guided targeting was validated with films and compared with the CBCT-guided delivery. In vivo experiments were conducted to demonstrate BLT localization capability for various source geometries. Results: Online BLT was able to recover the CoM of the embedded light source with an average accuracy of 1 mm compared to that with CBCT localization. Differences between BLT- and CBCT-guided irradiation shown on the films were consistent with the source localization revealed in the BLT and CBCT images. In vivo results demonstrated that our BLT system could potentially be applied for multiple targets and tumors. Conclusions: The online BLT/CBCT/SARRP system provides an effective solution for soft tissue targeting, particularly for small, nonpalpable, or

  13. ServiceNow as a platform – practical research

    OpenAIRE

    Nechyporenko, Tamara

    2015-01-01

    In this thesis I am going to cover the main aspects of ServiceNow platform, what is it, and related areas to ServiceNow technologies such as cloud service technologies and ITIL framework, how it is used in ServiceNow. All the definitions and descriptions will be in details and a reader can get the important terms and definitions. The main scope of the thesis is practical research and creation of portal based on that research. The portal will be implemented using ServiceNow platform, Servic...

  14. Research of Snow-Melt Process on a Heated Platform

    Directory of Open Access Journals (Sweden)

    Vasilyev Gregory P.

    2016-01-01

    Full Text Available The article has shown the results of experimental researches of the snow-melt on a heated platform-near building heat-pump snow-melt platform. The near-building (yard heat pump platforms for snow melt with the area up to 10-15 m2 are a basis of the new ideology of organization of the street cleaning of Moscow from snow in the winter period which supposes the creation in the megalopolis of the «distributed snow-melt system» (DSMS using non-traditional energy sources. The results of natural experimental researches are presented for the estimation of efficiency of application in the climatic conditions of Moscow of heat pumps in the snow-melt systems. The researches were conducted on a model sample of the near-building heat-pump platform which uses the low-potential thermal energy of atmospheric air. The conducted researches have confirmed experimentally in the natural conditions the possibility and efficiency of using of atmospheric air as a source of low-potential thermal energy for evaporation of the snow-melt heat pump systems in the climatic conditions of Moscow. The results of laboratory researches of snow-melt process on a heated horizontal platform are presented. The researches have revealed a considerable dependence of efficiency of the snow-melt process on its piling mode (form-building and the organization of the process of its piling mode (form-building and the organization of the process of its (snow mass heat exchange with the surface of the heated platform. In the process of researches the effect of formation of an «ice dome» under the melting snow mass called by the fact that in case of the thickness of snow loaded on the platform more than 10 cm the water formed from the melting snow while the contact with the heating surface don’t spread on it, but soaks into the snow, wets it due to capillary effect and freezes. The formation of «ice dome» leads to a sharp increase of snow-melt period and decreases the operating

  15. Nuclear platform research and development - 2008-09 highlights

    International Nuclear Information System (INIS)

    Sadhankar, R.R.

    2009-08-01

    The Nuclear Platform R and D Program has lead responsibility for the maintenance and further development of the CANDU intellectual property covering the safety, licensing and design basis for nuclear facilities. The Nuclear Platform R and D Program is part of the Research and Technology Operation (RTO) unit of AECL and is managed through the Research and Development division, which has responsibility for maintaining and enhancing the knowledge and technology base. The RTO is also responsible for managing AECL's nuclear facilities and infrastructure (including laboratories and R and D facilities), the nuclear waste management program and other legacy liabilities (e.g., decommissioning) to demonstrate and grow shareholder value. The Nuclear Platform also provides the technology base from which new products and services can be developed to meet customer needs (including ACR and commercial products and services). (author)

  16. [Platforms are needed for innovative basic research in ophthalmology].

    Science.gov (United States)

    Wang, Yi-qiang

    2012-07-01

    Basic research poses the cornerstone of technical innovation in all lines including medical sciences. Currently, there are shortages of professional scientists as well as technical supporting teams and facilities in the field of basic research of ophthalmology and visual science in China. Evaluation system and personnel policies are not supportive for innovative but high-risk-of-failure research projects. Discussion of reasons and possible solutions are given here to address these problems, aiming at promoting buildup of platforms hosting novel and important basic research in eye science in this country.

  17. Action-research platforms in water and agriculture: Lessons from three programmes in Africa

    CSIR Research Space (South Africa)

    Tucker, J

    2013-05-01

    Full Text Available Stakeholder platforms are popular among agricultural innovation projects. However, there has been limited critical or comparative research on these platforms, exploring what outcomes can be expected and what makes platforms effective or sustainable...

  18. Raven-II: an open platform for surgical robotics research.

    Science.gov (United States)

    Hannaford, Blake; Rosen, Jacob; Friedman, Diana W; King, Hawkeye; Roan, Phillip; Cheng, Lei; Glozman, Daniel; Ma, Ji; Kosari, Sina Nia; White, Lee

    2013-04-01

    The Raven-II is a platform for collaborative research on advances in surgical robotics. Seven universities have begun research using this platform. The Raven-II system has two 3-DOF spherical positioning mechanisms capable of attaching interchangeable four DOF instruments. The Raven-II software is based on open standards such as Linux and ROS to maximally facilitate software development. The mechanism is robust enough for repeated experiments and animal surgery experiments, but is not engineered to sufficient safety standards for human use. Mechanisms in place for interaction among the user community and dissemination of results include an electronic forum, an online software SVN repository, and meetings and workshops at major robotics conferences.

  19. Issues in offshore platform research - Part 1: Semi-submersibles

    Science.gov (United States)

    Sharma, R.; Kim, Tae-Wan; Sha, O. P.; Misra, S. C.

    2010-09-01

    Availability of economic and efficient energy resources is crucial to a nation's development. Because of their low cost and advancement in drilling and exploration technologies, oil and gas based energy systems are the most widely used energy source throughout the world. The inexpensive oil and gas based energy systems are used for everything, i.e., from transportation of goods and people to the harvesting of crops for food. As the energy demand continues to rise, there is strong need for inexpensive energy solutions. An offshore platform is a large structure that is used to house workers and machinery needed to drill wells in the ocean bed, extract oil and/or natural gas, process the produced fluids, and ship or pipe them to shore. Depending on the circumstances, the offshore platform can be fixed (to the ocean floor) or can consist of an artificial island or can float. Semi-submersibles are used for various purposes in offshore and marine engineering, e.g. crane vessels, drilling vessels, tourist vessels, production platforms and accommodation facilities, etc. The challenges of deepwater drilling have further motivated the researchers to design optimum choices for semi-submersibles for a chosen operating depth. In our series of eight papers, we discuss the design and production aspects of all the types of offshore platforms. In the present part I, we present an introduction and critical analysis of semi-submersibles.

  20. Issues in offshore platform research - Part 1: Semi-submersibles

    Directory of Open Access Journals (Sweden)

    R. Sharma

    2010-09-01

    Full Text Available Availability of economic and efficient energy resources is crucial to a nation's development. Because of their low cost and advancement in drilling and exploration technologies, oil and gas based energy systems are the most widely used energy source throughout the world. The inexpensive oil and gas based energy systems are used for everything, i.e., from transportation of goods and people to the harvesting of crops for food. As the energy demand continues to rise, there is strong need for inexpensive energy solutions. An offshore platform is a large structure that is used to house workers and machinery needed to drill wells in the ocean bed, extract oil and/or natural gas, process the produced fluids, and ship or pipe them to shore. Depending on the circumstances, the offshore platform can be fixed (to the ocean floor or can consist of an artificial island or can float. Semi-submersibles are used for various purposes in offshore and marine engineering, e.g. crane vessels, drilling vessels, tourist vessels, production platforms and accommodation facilities, etc. The challenges of deepwater drilling have further motivated the researchers to design optimum choices for semi-submersibles for a chosen operating depth. In our series of eight papers, we discuss the design and production aspects of all the types of offshore platforms. In the present part I, we present an introduction and critical analysis of semi-submersibles.

  1. West African Platform for HIV Intervention Research (WAPHIR ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    West African Platform for HIV Intervention Research (WAPHIR) : plateforme de recherche interventionnelle en matière de VIH en Afrique de l'Ouest. Grâce à cette subvention, on appuiera l'établissement d'un partenariat dirigé par des Africains de l'Ouest, en collaboration avec des partenaires canadiens et européens, afin ...

  2. Health Information Research Platform (HIReP)--an architecture pattern.

    Science.gov (United States)

    Schreiweis, Björn; Schneider, Gerd; Eichner, Theresia; Bergh, Björn; Heinze, Oliver

    2014-01-01

    Secondary use or single source is still far from routine in healthcare, although lots of data are available either structured or unstructured. As data are stored in multiple systems, using them for biomedical research is difficult. Clinical data warehouses already help overcoming this issue, but currently they are only used for certain parts of biomedical research. A comprehensive research platform based on a generic architecture pattern could increase the benefits of existing data warehouses for both patient care and research by meeting two objectives: serving as a so called single point-of-truth and acting as a mediator between them strengthening interaction and close collaboration. Another effect is to reduce boundaries for the implementation of data warehouses. Taking further settings into account the architecture of a clinical data warehouse supporting patient care and biomedical research needs to be integrated with biomaterial banks and other sources. This work provides a solution conceptualizing a comprehensive architecture pattern of a Health Information Research Platform (HIReP) derived from use cases of the patient care and biomedical research domain. It serves as single IT infrastructure providing solutions for any type of use case.

  3. NASA's Platform for Cross-Disciplinary Microchannel Research

    Science.gov (United States)

    Son, Sang Young; Spearing, Scott; Allen, Jeffrey; Monaco, Lisa A.

    2003-01-01

    A team from the Structural Biology group located at the NASA Marshall Space Flight Center in Huntsville, Alabama is developing a platform suitable for cross-disciplinary microchannel research. The original objective of this engineering development effort was to deliver a multi-user flight-certified facility for iterative investigations of protein crystal growth; that is, Iterative Biological Crystallization (IBC). However, the unique capabilities of this facility are not limited to the low-gravity structural biology research community. Microchannel-based research in a number of other areas may be greatly accelerated through use of this facility. In particular, the potential for gas-liquid flow investigations and cellular biological research utilizing the exceptional pressure control and simplified coupling to macroscale diagnostics inherent in the IBC facility will be discussed. In conclusion, the opportunities for research-specific modifications to the microchannel configuration, control, and diagnostics will be discussed.

  4. The Design:Lab as platform in participatory design research

    DEFF Research Database (Denmark)

    Binder, Thomas; Brandt, Eva

    2008-01-01

    The notion of laboratory or simply 'lab' has become popular in recent years in areas outside science and technology development. Learning Labs, Innovation Labs, Usability Labs, Media and Communication Labs and even Art Labs designate institutions or fora dedicated to change and experimentation...... as others have frequently used other metaphors like workshop, studio or atelier in design research. In this article we will argue that the laboratory metaphor is particularly suitable and useful for the design:lab, and we will give examples of how we have worked with the design:lab as a platform...

  5. Development of the Research Platform of Small Autonomous Blimp Robot

    Science.gov (United States)

    Takaya, Toshihiko; Kawamura, Hidenori; Yamamoto, Masahito; Ohuchi, Azuma

    A blimp robot is attractive as an small flight robot and can float in the air by buoyancy and realize safe to the crash small flight with low energy and can movement for a long time compared with other flight robots with low energy and can movement for a long time compared with other flight robots. However, control of an airplane robot is difficult for the nonlinear characteristic exposed to inertia by the air flow in response to influence. Therefore, the applied research which carried out the maximum use of such in recent years a blimp robot's feature is prosperous. In this paper, we realized development of blimp robot for research which can be used general-purpose by carrying out clue division of the blimp robot body at a unit, and constituting and building for research of blimp robot, and application development. On the other hand, by developing a general-purpose blimp robot research platform, improvement in the research efficiency of many researchers can be attained, and further, research start of blimp robot becomes easy and contributes to development of research. We performed the experiments for the above-mentioned proof. 1. Checked basic keeping position performance and that various orbital operation was possible. And the unit exchange ease of software unit was checked by the experiment which exchanges the control layer of software for learning control from PID control, and carries out comparison of operation. 2. In order to check the exchange ease of hardware unit, the sensor was exchanged for the microphon from the camera, and control of operation was checked. 3. For the unit addition ease, the microphon which carries out sound detection with the picture detection with a camera was added, and control of operation was verified. 4. The unit exchange was carried out for the check of a function addition and the topological map generation experiment by addition of an ultrasonic sensor was conducted. Developed blimp robot for research mounted the exchange ease

  6. A platform for quality management in research institutes (part II

    Directory of Open Access Journals (Sweden)

    Klembalska Agnieszka

    2016-09-01

    Full Text Available In the recent years there has been a particularly strong pressure on changing old structures and management models in research institutes. Contemporary research institutes are scientific units which are commercial in character – almost 80% of funds come from companies and contractual research activity and services. They are the basic sector of science aiming at cooperation with the economy, applied and innovative research. In order to maintain the current and start new cooperation it is necessary to pay particular attention to maintaining, improving and exposing high level of quality of conducted activity. Taking into consideration the necessity of carrying out ever more complex research projects, conducting activity requiring fast reaction to change, risk analysis, which is assessed every year by the Ministry of Science and Higher Education – it seems that it is necessary to apply tools supporting the assessment of quality. In the proposed three-aspect perspective the following scopes of activity are emphasized: implemented quality management systems, area of scientific information and the sphere of cooperation with the client. This article constitutes the continuation of the subjects discussed in the first part – an extension of issues associated with the scope of responsibilities of particular Sections of the proposed Quality Management Platform in research institutes.

  7. Towards A Research Agenda on Digital Platform Disruption

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    Digital platforms are disruptive IT artifacts, because they facilitate the quick release of innovative platform derivatives from third parties. This study endeavors to unravel the disruptive potential, caused by distinct designs and configurations of digital platforms on market environments. We...... postulate that the disruptive potential of digital platforms is determined by the degree of alignment among the business, technology and platform profiles. Furthermore, we argue that the design and configuration of the aforementioned three elements dictates the extent to which open innovation is permitted....... To shed light on the disruptive potential of digital platforms, we opted for digital payment platforms as our unit of analysis. Through interviews with experts and payment providers, we seek to gain an in-depth appreciation of how contemporary digital payment platforms are designed and configured...

  8. NEON's Mobile Deployment Platform: A Resource for Community Research

    Science.gov (United States)

    Sanclements, M.

    2015-12-01

    Here we provide an update on construction and validation of the NEON Mobile Deployment Platforms (MDPs) as well as a description of the infrastructure and sensors available to researchers in the future. The MDPs will provide the means to observe stochastic or spatially important events, gradients, or quantities that cannot be reliably observed using fixed location sampling (e.g. fires and floods). Due to the transient temporal and spatial nature of such events, the MDPs will be designed to accommodate rapid deployment for time periods up to ~ 1 year. Broadly, the MDPs will be comprised of infrastructure and instrumentation capable of functioning individually or in conjunction with one another to support observations of ecological change, as well as education, training and outreach.

  9. NEON's Mobile Deployment Platform: A Resource for Community Research

    Science.gov (United States)

    Sanclements, M.

    2017-12-01

    Here we provide an update on construction of the five NEON Mobile Deployment Platforms (MDPs) as well as a description of the infrastructure and sensors available to researchers in the near future. Additionally, we include information (i.e. timelines and procedures) on requesting MDPs for PI led projects. The MDPs will provide the means to observe stochastic or spatially important events, gradients, or quantities that cannot be reliably observed using fixed location sampling (e.g. fires and floods). Due to the transient temporal and spatial nature of such events, the MDPs are designed to accommodate rapid deployment for time periods up to 1 year. Broadly, the MDPs are comprised of infrastructure and instrumentation capable of functioning individually or in conjunction with one another to support observations of ecological change, as well as education, training and outreach. More specifically, the MDPs include the capability to make tower based measures of ecosystem exchange, radiation, and precipitation in conjunction with baseline soils data such as CO2 flux, and soil temperature and moisture. An aquatics module is also available with the MDP to facilitate research integrating terrestrial and aquatic processes. Ultimately, the NEON MDPs provide a tool for linking PI led research to the continental scale data sets collected by NEON.

  10. DSF: A Common Platform for Distributed Systems Research and Development

    Science.gov (United States)

    Tang, Chunqiang

    This paper presents Distributed Systems Foundation (DSF), a common platform for distributed systems research and development. It can run a distributed algorithm written in Java under multiple execution modes—simulation, massive multi-tenancy, and real deployment. DSF provides a set of novel features to facilitate testing and debugging, including chaotic timing test and time travel debugging with mutable replay. Unlike existing research prototypes that offer advanced debugging features by hacking programming tools, DSF is written entirely in Java, without modifications to any external tools such as JVM, Java runtime library, compiler, linker, system library, OS, or hypervisor. This simplicity stems from our goal of making DSF not only a research prototype but more importantly a production tool. Experiments show that DSF is efficient and easy to use. DSF's massive multi-tenancy mode can run 4,000 OS-level threads in a single JVM to concurrently execute (as opposed to simulate) 1,000 DHT nodes in real-time.

  11. Software platform virtualization in chemistry research and university teaching.

    Science.gov (United States)

    Kind, Tobias; Leamy, Tim; Leary, Julie A; Fiehn, Oliver

    2009-11-16

    Modern chemistry laboratories operate with a wide range of software applications under different operating systems, such as Windows, LINUX or Mac OS X. Instead of installing software on different computers it is possible to install those applications on a single computer using Virtual Machine software. Software platform virtualization allows a single guest operating system to execute multiple other operating systems on the same computer. We apply and discuss the use of virtual machines in chemistry research and teaching laboratories. Virtual machines are commonly used for cheminformatics software development and testing. Benchmarking multiple chemistry software packages we have confirmed that the computational speed penalty for using virtual machines is low and around 5% to 10%. Software virtualization in a teaching environment allows faster deployment and easy use of commercial and open source software in hands-on computer teaching labs. Software virtualization in chemistry, mass spectrometry and cheminformatics is needed for software testing and development of software for different operating systems. In order to obtain maximum performance the virtualization software should be multi-core enabled and allow the use of multiprocessor configurations in the virtual machine environment. Server consolidation, by running multiple tasks and operating systems on a single physical machine, can lead to lower maintenance and hardware costs especially in small research labs. The use of virtual machines can prevent software virus infections and security breaches when used as a sandbox system for internet access and software testing. Complex software setups can be created with virtual machines and are easily deployed later to multiple computers for hands-on teaching classes. We discuss the popularity of bioinformatics compared to cheminformatics as well as the missing cheminformatics education at universities worldwide.

  12. Research on University Network Teaching Platform (Blackboard in Teaching Management

    Directory of Open Access Journals (Sweden)

    Gou Zhao Xia

    2016-01-01

    Full Text Available With rapid development of online education; teaching platform based on the network, as a new instructional mode has become a hot topic in online teaching. In this paper, the he teaching situation and existing problems on online was analyzed by comparing the difference between network teaching platform and traditional classroom teaching. Then the strategies of network teaching management and the case, which is focusing on the characteristics of Blackboard with the application of network teaching management was presents.

  13. AURORA BOREALIS: a polar-dedicated European Research Platform

    Science.gov (United States)

    Wolff-Boenisch, Bonnie; Egerton, Paul; Thiede, Joern; Roberto, Azzolini; Lembke-Jene, Lester

    2010-05-01

    Polar research and in particular the properties of northern and southern high latitude oceans are currently a subject of intense scientific debate and investigations, because they are subject to rapid and dramatic climatic variations. Polar regions react more rapidly and intensively to global change than other regions of the earth. A shrinking of the Arctic sea-ice cover, potentially leading to an opening of sea passages to the north of North America and Eurasia, on the long to a "blue" Arctic Ocean would additionally have a strong impact on transport, commerce and tourism bearing potential risk for humans and complex ecosystems in the future. In spite of their critical role processes and feedbacks, especially in winter but not exclusively, are virtually unknown: The Arctic Ocean for example, it is the only basin of the world's oceans that has essentially not been sampled by the drill ships of the Deep-Sea Drilling Project (DSDP) or the Ocean Drilling Program (ODP) and its long-term environmental history and tectonic structure is therefore poorly known. Exceptions are the ODP Leg 151 and the more recent very successful ACEX-expedition of the Integrated Ocean Drilling Program (IODP) in 2004. To help to address the most pressing questions regarding climate change and related processes, a Pan-European initiative in the field of Earth system science has been put in place: AURORA BOREALIS is the largest environmental research infrastructure on the ESFRI roadmap of the European Community. AURORA BOREALIS is a very powerful research icebreaker, which will enable year-round operations in the Arctic and the Antarctic as well as in the adjacent ocean basins. Equipped with its drilling rig, the vessel is also capable to explore the presently completely unknown Arctic deep-sea floor. Last but not least, the ship is a floating observatory and mobile monitoring platform that permits to measure on a long-term basis comprehensive time series in all research fields relevant to

  14. Can Nuclear Installations and Research Centres Adopt Cloud Computing Platform-

    International Nuclear Information System (INIS)

    Pichan, A.; Lazarescu, M.; Soh, S.T.

    2015-01-01

    Cloud Computing is arguably one of the recent and highly significant advances in information technology today. It produces transformative changes in the history of computing and presents many promising technological and economic opportunities. The pay-per-use model, the computing power, abundance of storage, skilled resources, fault tolerance and the economy of scale it offers, provides significant advantages to enterprises to adopt cloud platform for their business needs. However, customers especially those dealing with national security, high end scientific research institutions, critical national infrastructure service providers (like power, water) remain very much reluctant to move their business system to the cloud. One of the main concerns is the question of information security in the cloud and the threat of the unknown. Cloud Service Providers (CSP) indirectly encourages this perception by not letting their customers see what is behind their virtual curtain. Jurisdiction (information assets being stored elsewhere), data duplication, multi-tenancy, virtualisation and decentralized nature of data processing are the default characteristics of cloud computing. Therefore traditional approach of enforcing and implementing security controls remains a big challenge and largely depends upon the service provider. The other biggest challenge and open issue is the ability to perform digital forensic investigations in the cloud in case of security breaches. Traditional approaches to evidence collection and recovery are no longer practical as they rely on unrestricted access to the relevant systems and user data, something that is not available in the cloud model. This continues to fuel high insecurity for the cloud customers. In this paper we analyze the cyber security and digital forensics challenges, issues and opportunities for nuclear facilities to adopt cloud computing. We also discuss the due diligence process and applicable industry best practices which shall be

  15. Collaborative and cognitive network platforms : Vision and research challenges

    NARCIS (Netherlands)

    Onur, E.; Durmus, Y.; Hawas, M.G.; Heemstra de Groot, S.M.; Niemegeers, I.G.M.M.

    2011-01-01

    In this paper, we present a visionary concept referred to as Collaborative and Cognitive Network Platforms (CCNPs) as a future-proof solution for creating a dependable, self-organizing and self-managing communication substrate for effective ICT solutions to societal problems. CCNP creates a

  16. A new platform for RFID research in Vietnam

    International Nuclear Information System (INIS)

    Tran, Ai Nhan; Nguyen, Son Dat; Thai Pham, Duc Hoang; Nguyen, Thuat Tran; Dang, Chien Mau; Fribourg-Blanc, Eric

    2010-01-01

    Radio-Frequency IDentification (RFID) is a technology that has been emerging for less than a decade as the primary choice to exchange information between objects and their environment. Most of the challenges arise due to the passive nature of the tags placed on objects. The absence of a local power source implies that power management is critical for efficient work of the data exchange link. This paper presents the platform under development at the Laboratory for Nanotechnology to study these challenges. The primary goal of the platform is to implement the complete chain from design and simulation of tags to antenna measurements and field tests of tags through fabrication of real tags on flexible substrates. This structure allows for fundamental and practical studies of new concepts in sensing and wireless networks based on passive tags. A description of the actual achievements is also included

  17. Development of a Modular Research Platform to Create Medical Observational Studies for Mobile Devices.

    Science.gov (United States)

    Zens, Martin; Grotejohann, Birgit; Tassoni, Adrian; Duttenhoefer, Fabian; Südkamp, Norbert P; Niemeyer, Philipp

    2017-05-23

    Observational studies have proven to be a valuable resource in medical research, especially when performed on a large scale. Recently, mobile device-based observational studies have been discovered by an increasing number of researchers as a promising new source of information. However, the development and deployment of app-based studies is not trivial and requires profound programming skills. The aim of this project was to develop a modular online research platform that allows researchers to create medical studies for mobile devices without extensive programming skills. The platform approach for a modular research platform consists of three major components. A Web-based platform forms the researchers' main workplace. This platform communicates via a shared database with a platform independent mobile app. Furthermore, a separate Web-based login platform for physicians and other health care professionals is outlined and completes the concept. A prototype of the research platform has been developed and is currently in beta testing. Simple questionnaire studies can be created within minutes and published for testing purposes. Screenshots of an example study are provided, and the general working principle is displayed. In this project, we have created a basis for a novel research platform. The necessity and implications of a modular approach were displayed and an outline for future development given. International researchers are invited and encouraged to participate in this ongoing project. ©Martin Zens, Birgit Grotejohann, Adrian Tassoni, Fabian Duttenhoefer, Norbert P Südkamp, Philipp Niemeyer. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 23.05.2017.

  18. Research of MOOC Platform Based “Internet +”

    OpenAIRE

    Wang Guang Xing; Chen Yan

    2016-01-01

    This paper is devoted to examining the construction of MOOC platform based “Internet +”. It firstly introduced the “Internet+” model, the “Internet + education” influence and the significance of education. Then, it analyzed the existing problems in the development of the current MOOC, and put forward the model of “Internet + MOOC” through the method of software engineering. It explored the advantage of “Internet + MOOC” mode and promoting the function to the education teaching. This paper put...

  19. A cloud computing based platform for sleep behavior and chronic diseases collaborative research.

    Science.gov (United States)

    Kuo, Mu-Hsing; Borycki, Elizabeth; Kushniruk, Andre; Huang, Yueh-Min; Hung, Shu-Hui

    2014-01-01

    The objective of this study is to propose a Cloud Computing based platform for sleep behavior and chronic disease collaborative research. The platform consists of two main components: (1) a sensing bed sheet with textile sensors to automatically record patient's sleep behaviors and vital signs, and (2) a service-oriented cloud computing architecture (SOCCA) that provides a data repository and allows for sharing and analysis of collected data. Also, we describe our systematic approach to implementing the SOCCA. We believe that the new cloud-based platform can provide nurse and other health professional researchers located in differing geographic locations with a cost effective, flexible, secure and privacy-preserved research environment.

  20. Design of e-Science platform for biomedical imaging research cross multiple academic institutions and hospitals

    Science.gov (United States)

    Zhang, Jianguo; Zhang, Kai; Yang, Yuanyuan; Ling, Tonghui; Wang, Tusheng; Wang, Mingqing; Hu, Haibo; Xu, Xuemin

    2012-02-01

    More and more image informatics researchers and engineers are considering to re-construct imaging and informatics infrastructure or to build new framework to enable multiple disciplines of medical researchers, clinical physicians and biomedical engineers working together in a secured, efficient, and transparent cooperative environment. In this presentation, we show an outline and our preliminary design work of building an e-Science platform for biomedical imaging and informatics research and application in Shanghai. We will present our consideration and strategy on designing this platform, and preliminary results. We also will discuss some challenges and solutions in building this platform.

  1. Semantic Web-Based Services for Supporting Voluntary Collaboration among Researchers Using an Information Dissemination Platform

    Directory of Open Access Journals (Sweden)

    Hanmin Jung

    2007-05-01

    Full Text Available Information dissemination platforms for supporting voluntary collaboration among researchers should assure that controllable and verified information is being disseminated. However, previous related studies on this field narrowed their research scopes into information type and information specification. This paper focuses on the verification and the tracing of information using an information dissemination platform and other Semantic Web-based services. Services on our platform include information dissemination services to support reliable information exchange among researchers and knowledge service to provide unrevealed information. The latter is also divided into the two: knowledgization using ontology and inference using a Semantic Web-based inference engine. This paper discusses how this platform supports instant knowledge addition and inference. We demonstrate our approach by constructing an ontology for national R&D reference information using 37,656 RDF triples from about 2,300 KISTI (Korea Institute of Science and Technology Information outcomes. Three knowledge services including 'Communities of Practice', 'Researcher Tracing,' and 'Research Map' were implemented on our platform using a Jena framework. Our study shows that information dissemination platforms will make a meaningful contribution to the possibility of realizing a practical Semantic Web-based information dissemination platform.

  2. West African Platform for HIV Intervention Research (WAPHIR ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Project Leader ... The main objective of this competitive research fund is to support applied research in areas vital to achieving long-term food ... The Science Granting Councils Initiative in sub-Saharan Africa wins Science Diplomacy Award.

  3. Sharing Health Big Data for Research - A Design by Use Cases: The INSHARE Platform Approach.

    Science.gov (United States)

    Bouzillé, Guillaume; Westerlynck, Richard; Defossez, Gautier; Bouslimi, Dalel; Bayat, Sahar; Riou, Christine; Busnel, Yann; Le Guillou, Clara; Cauvin, Jean-Michel; Jacquelinet, Christian; Pladys, Patrick; Oger, Emmanuel; Stindel, Eric; Ingrand, Pierre; Coatrieux, Gouenou; Cuggia, Marc

    2017-01-01

    Sharing and exploiting Health Big Data (HBD) allow tackling challenges: data protection/governance taking into account legal, ethical, and deontological aspects enables trust, transparent and win-win relationship between researchers, citizens, and data providers. Lack of interoperability: compartmentalized and syntactically/semantica heterogeneous data. INSHARE project using experimental proof of concept explores how recent technologies overcome such issues. Using 6 data providers, platform is designed via 3 steps to: (1) analyze use cases, needs, and requirements; (2) define data sharing governance, secure access to platform; and (3) define platform specifications. Three use cases - from 5 studies and 11 data sources - were analyzed for platform design. Governance derived from SCANNER model was adapted to data sharing. Platform architecture integrates: data repository and hosting, semantic integration services, data processing, aggregate computing, data quality and integrity monitoring, Id linking, multisource query builder, visualization and data export services, data governance, study management service and security including data watermarking.

  4. Repurposing digital methods: The research affordances of platforms and engines

    NARCIS (Netherlands)

    Weltevrede, E.J.T.

    2016-01-01

    Digital research is often understood as data-driven. Yet the ways in which data are already informed by specific analytical assumptions and inscriptions of the media in which they originate, circulate, or are being used is often neglected. The thesis intervenes in such focus on digital research in

  5. Creating a Common Platform for HIV Vaccine Research and HIV ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    This will involve capacity building in clinical practice, research ethics, regulation, community mobilization, risk cohort development and clinical research, plus strengthening clinical laboratory facilities to the level of international certification. The idea is to achieve a fully functional clinical trials unit within a well engaged ...

  6. Remote sensing technology research and instrumentation platform design

    Science.gov (United States)

    1992-01-01

    An instrumented pallet concept and definition of an aircraft with performance and payload capability to meet NASA's airborne turbulent flux measurement needs for advanced multiple global climate research and field experiments is presented. The report addresses airborne measurement requirements for general circulation model sub-scale parameterization research, specifies instrumentation capable of making these measurements, and describes a preliminary support pallet design. Also, a review of aircraft types and a recommendation of a manned and an unmanned aircraft capable of meeting flux parameterization research needs is given.

  7. West African Platform for HIV Intervention Research (WAPHIR ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Giving girls and women the power to decide. Addressing Africa's unmet need for family planning by intensifying sexual and reproductive and adolescent health research. View moreGiving girls and women the power to decide ...

  8. Canary: An NLP Platform for Clinicians and Researchers.

    Science.gov (United States)

    Malmasi, Shervin; Sandor, Nicolae L; Hosomura, Naoshi; Goldberg, Matt; Skentzos, Stephen; Turchin, Alexander

    2017-05-03

    Information Extraction methods can help discover critical knowledge buried in the vast repositories of unstructured clinical data. However, these methods are underutilized in clinical research, potentially due to the absence of free software geared towards clinicians with little technical expertise. The skills required for developing/using such software constitute a major barrier for medical researchers wishing to employ these methods. To address this, we have developed Canary, a free and open-source solution designed for users without natural language processing (NLP) or software engineering experience. It was designed to be fast and work out of the box via a user-friendly graphical interface.

  9. Basic to industrial research on neutron platform in Japan

    Indian Academy of Sciences (India)

    Building on these successes, a new spallation neutron source (KENS) was con- structed at KEK (the present High Energy Accelerator Research Organization) in. 618. Pramana – J. Phys., Vol. 71, No. ... Ministry of Education, Science and Culture (MONBUSHO) planned the Hadron. Project consisting of four major facilities ...

  10. Operation and Maintenance of the Research Platform FLIP

    Science.gov (United States)

    2013-12-17

    by FLIP 2006 15Aug-11 Sept PI R. Pinkel, MPL , ONR, AESOP 02 Oct-04 Nov PI J. Hildebrand, MPL ONR Marine Mammal 2007 21 Feb-16Mar T. Golfinos ONR...Dry Dock in ARCO 30 Oct-29 Nov PIJ. Hildebrand, MPL ONR/N45 Marine Mammal 2008 03-25 Sep PI K. Melville, MPL ONR RaDyo Program 13 0ct-12Nov PI J...Hildebrand, MPL ONR Marine Mammal Research 2009 6-7 May PI K. Melville, MPL ONR Sea Trials 06-14 Jul PI K. Melville, MPL ONR ONR HiRes 03-13 Aug T

  11. Biomedical engineering: A platform for research and innovation in ultrasound

    Science.gov (United States)

    Holland, Christy K.

    2004-05-01

    An undergraduate or graduate degree in biomedical engineering prepares students to solve problems at the interface between engineering and medicine. Biomedical engineering encompasses evolving areas such as advanced medical imaging for diagnosis and treatment of disease, tissue engineering for designing and manufacturing biological implants for damaged or diseased tissues and organs, and bioinformatics for determining which genes play a major role in health and disease. Biomedical engineering academic programs produce graduates with the ability to pursue successful careers in the biomedical device industry or to obtain advanced degrees leading to careers in biomedical engineering research, medicine, law or business. Biomedical engineering majors take courses in biology, anatomy, physics, chemistry, engineering, mathematics and medical product design and value life-long learning. Students learn to work effectively in interdisciplinary teams comprised of individuals with diverse social, cultural and technical backgrounds. Biomedical engineering is becoming increasingly important in imaging and image-guided research. Some examples of innovative ultrasound technology under development are ultrasound devices to accelerate the dissolution of blood clots, advanced surgical instruments with ultrasound guidance and ultrasound contrast agents for targeted drug delivery. Biomedical engineering is a great career choice for technically minded individuals who endeavor to work on applied problems that are medically relevant.

  12. SimNEC : research platform for studying human functioning in NCW

    NARCIS (Netherlands)

    Veen, H.A.H.C. van; Graaf, B. de; Essens, P.

    2006-01-01

    SimNEC is TNOÆs grand scheme for experimentally studying human factors issues related to NEC/NCW. The research platform SimNEC consists of multidisciplinary expert teams, long-term research programmes, and a local network of state-of-the-art simulator modules. SimNEC does not focus on technology,

  13. A Multidisciplinary, Open Access Platform for Research on Biomolecules

    Directory of Open Access Journals (Sweden)

    Jürg Bähler

    2011-08-01

    Full Text Available I am pleased to introduce Biomolecules, a new journal to report on all aspects of science that focuses on biologically derived substances, from small molecules to complex polymers. Some examples are lipids, carbohydrates, vitamins, hormones, amino acids, nucleotides, peptides, RNA and polysaccharides, but this list is far from exhaustive. Research on biomolecules encompasses multiple fascinating questions. How are biomolecules synthesized and modified? What are their structures and interactions with other biomolecules? How do biomolecules function in biological processes, at the level of organelles, cells, organs, organisms, or even ecosystems? How do biomolecules affect either the organism that produces them or other organisms of the same or different species? How are biomolecules shaped by evolution, and how in turn do they affect cellular phenotypes? What is the systems-level contribution of biomolecules to biological function?

  14. A Multidisciplinary, Open Access Platform for Research on Biomolecules.

    Science.gov (United States)

    Bähler, Jürg

    2011-08-22

    I am pleased to introduce Biomolecules, a new journal to report on all aspects of science that focuses on biologically derived substances, from small molecules to complex polymers. Some examples are lipids, carbohydrates, vitamins, hormones, amino acids, nucleotides, peptides, RNA and polysaccharides, but this list is far from exhaustive. Research on biomolecules encompasses multiple fascinating questions. How are biomolecules synthesized and modified? What are their structures and interactions with other biomolecules? How do biomolecules function in biological processes, at the level of organelles, cells, organs, organisms, or even ecosystems? How do biomolecules affect either the organism that produces them or other organisms of the same or different species? How are biomolecules shaped by evolution, and how in turn do they affect cellular phenotypes? What is the systems-level contribution of biomolecules to biological function? [...].

  15. European research platform IPANEMA at the SOLEIL synchrotron for ancient and historical materials

    International Nuclear Information System (INIS)

    Bertrand, L.; Languille, M.A.; Cohen, S.X.; Robinet, L.; Josse, W.; Gervais, C.; Leroy, S.; Bernard, D.; Le Pennec, E.; Doucet, J.; Schoder, S.

    2011-01-01

    IPANEMA, a research platform devoted to ancient and historical materials (archaeology, cultural heritage, palaeontology and past environments), is currently being set up at the synchrotron facility SOLEIL (Saint-Aubin, France; SOLEIL opened to users in January 2008). The new platform is open to French, European and international users. The activities of the platform are centred on two main fields: increased support to synchrotron projects on ancient materials and methodological research. The IPANEMA team currently occupies temporary premises at SOLEIL, but the platform comprises construction of a new building that will comply with conservation and environmental standards and of a hard X-ray imaging beamline today in its conceptual design phase, named PUMA. Since 2008, the team has supported synchrotron works at SOLEIL and at European synchrotron facilities on a range of topics including pigment degradation in paintings, composition of musical instrument varnishes, and provenancing of medieval archaeological ferrous artefacts. Once the platform is fully operational, user support will primarily take place within medium-term research projects for 'hosted' scientists, PhDs and post-docs. IPANEMA methodological research is focused on advanced two-dimensional/ three-dimensional imaging and spectroscopy and statistical image analysis, both optimized for ancient materials. (authors)

  16. New Tools for New Research in Psychiatry: A Scalable and Customizable Platform to Empower Data Driven Smartphone Research.

    Science.gov (United States)

    Torous, John; Kiang, Mathew V; Lorme, Jeanette; Onnela, Jukka-Pekka

    2016-05-05

    A longstanding barrier to progress in psychiatry, both in clinical settings and research trials, has been the persistent difficulty of accurately and reliably quantifying disease phenotypes. Mobile phone technology combined with data science has the potential to offer medicine a wealth of additional information on disease phenotypes, but the large majority of existing smartphone apps are not intended for use as biomedical research platforms and, as such, do not generate research-quality data. Our aim is not the creation of yet another app per se but rather the establishment of a platform to collect research-quality smartphone raw sensor and usage pattern data. Our ultimate goal is to develop statistical, mathematical, and computational methodology to enable us and others to extract biomedical and clinical insights from smartphone data. We report on the development and early testing of Beiwe, a research platform featuring a study portal, smartphone app, database, and data modeling and analysis tools designed and developed specifically for transparent, customizable, and reproducible biomedical research use, in particular for the study of psychiatric and neurological disorders. We also outline a proposed study using the platform for patients with schizophrenia. We demonstrate the passive data capabilities of the Beiwe platform and early results of its analytical capabilities. Smartphone sensors and phone usage patterns, when coupled with appropriate statistical learning tools, are able to capture various social and behavioral manifestations of illnesses, in naturalistic settings, as lived and experienced by patients. The ubiquity of smartphones makes this type of moment-by-moment quantification of disease phenotypes highly scalable and, when integrated within a transparent research platform, presents tremendous opportunities for research, discovery, and patient health.

  17. New Tools for New Research in Psychiatry: A Scalable and Customizable Platform to Empower Data Driven Smartphone Research

    OpenAIRE

    Torous, John; Kiang, Mathew V; Lorme, Jeanette; Onnela, Jukka-Pekka

    2016-01-01

    Background A longstanding barrier to progress in psychiatry, both in clinical settings and research trials, has been the persistent difficulty of accurately and reliably quantifying disease phenotypes. Mobile phone technology combined with data science has the potential to offer medicine a wealth of additional information on disease phenotypes, but the large majority of existing smartphone apps are not intended for use as biomedical research platforms and, as such, do not generate research-qu...

  18. PARAMO: a PARAllel predictive MOdeling platform for healthcare analytic research using electronic health records.

    Science.gov (United States)

    Ng, Kenney; Ghoting, Amol; Steinhubl, Steven R; Stewart, Walter F; Malin, Bradley; Sun, Jimeng

    2014-04-01

    Healthcare analytics research increasingly involves the construction of predictive models for disease targets across varying patient cohorts using electronic health records (EHRs). To facilitate this process, it is critical to support a pipeline of tasks: (1) cohort construction, (2) feature construction, (3) cross-validation, (4) feature selection, and (5) classification. To develop an appropriate model, it is necessary to compare and refine models derived from a diversity of cohorts, patient-specific features, and statistical frameworks. The goal of this work is to develop and evaluate a predictive modeling platform that can be used to simplify and expedite this process for health data. To support this goal, we developed a PARAllel predictive MOdeling (PARAMO) platform which (1) constructs a dependency graph of tasks from specifications of predictive modeling pipelines, (2) schedules the tasks in a topological ordering of the graph, and (3) executes those tasks in parallel. We implemented this platform using Map-Reduce to enable independent tasks to run in parallel in a cluster computing environment. Different task scheduling preferences are also supported. We assess the performance of PARAMO on various workloads using three datasets derived from the EHR systems in place at Geisinger Health System and Vanderbilt University Medical Center and an anonymous longitudinal claims database. We demonstrate significant gains in computational efficiency against a standard approach. In particular, PARAMO can build 800 different models on a 300,000 patient data set in 3h in parallel compared to 9days if running sequentially. This work demonstrates that an efficient parallel predictive modeling platform can be developed for EHR data. This platform can facilitate large-scale modeling endeavors and speed-up the research workflow and reuse of health information. This platform is only a first step and provides the foundation for our ultimate goal of building analytic pipelines

  19. eTRIKS platform: Conception and operation of a highly scalable cloud-based platform for translational research and applications development.

    Science.gov (United States)

    Bussery, Justin; Denis, Leslie-Alexandre; Guillon, Benjamin; Liu, Pengfeï; Marchetti, Gino; Rahal, Ghita

    2018-04-01

    We describe the genesis, design and evolution of a computing platform designed and built to improve the success rate of biomedical translational research. The eTRIKS project platform was developed with the aim of building a platform that can securely host heterogeneous types of data and provide an optimal environment to run tranSMART analytical applications. Many types of data can now be hosted, including multi-OMICS data, preclinical laboratory data and clinical information, including longitudinal data sets. During the last two years, the platform has matured into a robust translational research knowledge management system that is able to host other data mining applications and support the development of new analytical tools. Copyright © 2018 Elsevier Ltd. All rights reserved.

  20. EPOS Thematic Core Service ANTHROPOGENIC HAZARDS (TCS AH) - development of e-research platform

    Science.gov (United States)

    Orlecka-Sikora, Beata

    2017-04-01

    TCS AH is based on IS-EPOS Platform. The Platform facilitates research on anthropogenic hazards and is available online, free of charge https://tcs.ah-epos.eu/. The Platform is a final product of the IS-EPOS project, founded by the national programme - POIG - which was implemented in 2013-2015 (POIG.02.03.00-14-090/13-00). The platform is a result of a joint work of scientific community and industrial partners. Currently, the development of TCS AH is carried under EPOS IP project (H2020-INFRADEV-1-2015-1, INFRADEV-3-2015). Platform is an open virtual access point for researchers and Ph. D. students interested in anthropogenic seismicity and related hazards. This environment is designed to ensure a researcher the maximum possible liberty for experimentation by providing a virtual laboratory, in which the researcher can design own processing streams and process the data integrated on the platform. TCS AH integrates: data and specific high-level services. Data gathered in the so-called "episodes", comprehensively describing a geophysical process, induced or triggered by human technological activity, which, under certain circumstances can become hazardous for people, infrastructure and the environment. 7 sets of seismic, geological and technological data were made available on the Platform. The data come from Poland, Germany, UK and Vietnam, and refer to underground mining, reservoir impoundment, shale gas exploitation and geothermal energy production. The next at least 19 new episodes related to conventional hydrocarbon extraction, reservoir treatment, underground mining and geothermal energy production are being integrated within the framework of EPOS IP project. The heterogeneous multi-disciplinary data (seismic, displacement, geomechanical data, production data etc.) are transformed to unified structures to form integrated and validated datasets. To deal with this various data the problem-oriented services were designed and implemented. The particular attention

  1. The Research of China's Civil Aviation Passenger Multi-Channel Service Technology Platform

    Science.gov (United States)

    Zhibing, Xue; Xinming, Wang

    IATA is promoting Simplifying the Business. The traditional passenger services and business process, such as ticketing, airport counters, had a great influence. The airlines have the passenger service and convenience as the next product development requirements. With civil aviation industry and their company's products construction, the authors propose a solution of passenger multi-channel service product platform. The solution is to streamline the business as the breakthrough point, around the convenience of passengers travel services to travelers as the center, using the current mainstream and the latest IT technology to establish passenger service product platform. The solution will promote DCS e-ticketing business development and service channel diversity. In this paper, the research results have been applied in the product platform construction of the authors' company. The practice shows that through traditional business with the latest IT technologies, traditional passenger services into the emerging service model, passenger service product platform has strong advantages and characteristics. Based on the platform, various types of service products is growing rapidly.

  2. Direct2Experts: a pilot national network to demonstrate interoperability among research-networking platforms

    OpenAIRE

    Weber, Griffin M; Barnett, William; Conlon, Mike; Eichmann, David; Kibbe, Warren; Falk-Krzesinski, Holly; Halaas, Michael; Johnson, Layne; Meeks, Eric; Mitchell, Donald; Schleyer, Titus; Stallings, Sarah; Warden, Michael; Kahlon, Maninder

    2011-01-01

    Research-networking tools use data-mining and social networking to enable expertise discovery, matchmaking and collaboration, which are important facets of team science and translational research. Several commercial and academic platforms have been built, and many institutions have deployed these products to help their investigators find local collaborators. Recent studies, though, have shown the growing importance of multiuniversity teams in science. Unfortunately, the lack of a standard dat...

  3. Application Platform for Intelligent Mobility – research facility for intelligent mobility services

    OpenAIRE

    Schnieder, Lars

    2012-01-01

    Traffic can be seen as a multi-dimensional field of research. Traffic can be best described as a socio-technical system which brings about new challenges for the design of future transportation systems. With its Application Platform for Intelligent Mobility (AIM), the German Aerospace Center (DLR), together with the state of Lower Saxony, the city of Braunschweig and other partners, is creating a unique way of linking up research, development and applications for intelligent transportation an...

  4. Review of the severe accident risk reduction program (SARRP) containment event trees

    International Nuclear Information System (INIS)

    1986-05-01

    A part of the Severe Accident Risk Reduction Program, researchers at Sandia National Laboratories have constructed a group of containment event trees to be used in the analysis of key accident sequences for light water reactors (LWR) during postulated severe accidents. The ultimate goal of the program is to provide to the NRC staff a current assessment of the risk from severe reactor accidents for a group of five light water reactors. This review specifically focuses on the development and construction of the containment event trees and the results for containment failure probability, modes and timing. The report first gives the background on the program, the review criteria, and a summary of the observations, findings and recommendations. secondly, the individual reviews of each committee member on the event trees is presented. Finally, a review is provided on the computer model used to construct and evaluate the event trees

  5. e-Science platform for translational biomedical imaging research: running, statistics, and analysis

    Science.gov (United States)

    Wang, Tusheng; Yang, Yuanyuan; Zhang, Kai; Wang, Mingqing; Zhao, Jun; Xu, Lisa; Zhang, Jianguo

    2015-03-01

    In order to enable multiple disciplines of medical researchers, clinical physicians and biomedical engineers working together in a secured, efficient, and transparent cooperative environment, we had designed an e-Science platform for biomedical imaging research and application cross multiple academic institutions and hospitals in Shanghai and presented this work in SPIE Medical Imaging conference held in San Diego in 2012. In past the two-years, we implemented a biomedical image chain including communication, storage, cooperation and computing based on this e-Science platform. In this presentation, we presented the operating status of this system in supporting biomedical imaging research, analyzed and discussed results of this system in supporting multi-disciplines collaboration cross-multiple institutions.

  6. The RUDY study platform – a novel approach to patient driven research in rare musculoskeletal diseases

    Directory of Open Access Journals (Sweden)

    M. K. Javaid

    2016-11-01

    Full Text Available Abstract Background Research into rare diseases is becoming more common, with recognition of the significant diagnostic and therapeutic care gaps. Registries are considered a key research methodology to address rare diseases. This report describes the structure of the Rare UK Diseases Study (RUDY platform that aims to improve research processes and address many of the challenges of carrying out rare musculoskeletal disease research. RUDY is an internet-based platform with online registration, initial verbal consent, online capture of patient reported outcome measures and events within a dynamic consent framework. The database structure, security and governance framework are described. Results There have been 380 participants recruited into RUDY with completed questionnaire rates in excess of 50 %. There has been one withdrawal and two participants have amended their consent options. Conclusions The strengths of RUDY include low burden for the clinical team, low research administration costs with high participant recruitment and ease of data collection and access. This platform has the potential to be used as the model for other rare diseases globally.

  7. Dynamic simulation platform to verify the performance of the reactor regulating system for a research reactor

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-07-01

    Digital instrumentation and controls system technique is being introduced in new constructed research reactor or life extension of older research reactor. Digital systems are easy to change and optimize but the validated process for them is required. Also, to reduce project risk or cost, we have to make it sure that configuration and control functions is right before the commissioning phase on research reactor. For this purpose, simulators have been widely used in developing control systems in automotive and aerospace industries. In these literatures, however, very few of these can be found regarding test on the control system of research reactor with simulator. Therefore, this paper proposes a simulation platform to verify the performance of RRS (Reactor Regulating System) for research reactor. This simulation platform consists of the reactor simulation model and the interface module. This simulation platform is applied to I and C upgrade project of TRIGA reactor, and many problems of RRS configuration were found and solved. And it proved that the dynamic performance testing based on simulator enables significant time saving and improves economics and quality for RRS in the system test phase. (authors)

  8. Development of a Novel Preclinical Pancreatic Cancer Research Model: Bioluminescence Image-Guided Focal Irradiation and Tumor Monitoring of Orthotopic Xenografts1

    Science.gov (United States)

    Tuli, Richard; Surmak, Andrew; Reyes, Juvenal; Hacker-Prietz, Amy; Armour, Michael; Leubner, Ashley; Blackford, Amanda; Tryggestad, Erik; Jaffee, Elizabeth M; Wong, John; DeWeese, Theodore L; Herman, Joseph M

    2012-01-01

    PURPOSE: We report on a novel preclinical pancreatic cancer research model that uses bioluminescence imaging (BLI)-guided irradiation of orthotopic xenograft tumors, sparing of surrounding normal tissues, and quantitative, noninvasive longitudinal assessment of treatment response. MATERIALS AND METHODS: Luciferase-expressing MiaPaCa-2 pancreatic carcinoma cells were orthotopically injected in nude mice. BLI was compared to pathologic tumor volume, and photon emission was assessed over time. BLI was correlated to positron emission tomography (PET)/computed tomography (CT) to estimate tumor dimensions. BLI and cone-beam CT (CBCT) were used to compare tumor centroid location and estimate setup error. BLI and CBCT fusion was performed to guide irradiation of tumors using the small animal radiation research platform (SARRP). DNA damage was assessed by γ-H2Ax staining. BLI was used to longitudinally monitor treatment response. RESULTS: Bioluminescence predicted tumor volume (R = 0.8984) and increased linearly as a function of time up to a 10-fold increase in tumor burden. BLI correlated with PET/CT and necropsy specimen in size (P < .05). Two-dimensional BLI centroid accuracy was 3.5 mm relative to CBCT. BLI-guided irradiated pancreatic tumors stained positively for γ-H2Ax, whereas surrounding normal tissues were spared. Longitudinal assessment of irradiated tumors with BLI revealed significant tumor growth delay of 20 days relative to controls. CONCLUSIONS: We have successfully applied the SARRP to a bioluminescent, orthotopic preclinical pancreas cancer model to noninvasively: 1) allow the identification of tumor burden before therapy, 2) facilitate image-guided focal radiation therapy, and 3) allow normalization of tumor burden and longitudinal assessment of treatment response. PMID:22496923

  9. Development of a novel preclinical pancreatic cancer research model: bioluminescence image-guided focal irradiation and tumor monitoring of orthotopic xenografts.

    Science.gov (United States)

    Tuli, Richard; Surmak, Andrew; Reyes, Juvenal; Hacker-Prietz, Amy; Armour, Michael; Leubner, Ashley; Blackford, Amanda; Tryggestad, Erik; Jaffee, Elizabeth M; Wong, John; Deweese, Theodore L; Herman, Joseph M

    2012-04-01

    We report on a novel preclinical pancreatic cancer research model that uses bioluminescence imaging (BLI)-guided irradiation of orthotopic xenograft tumors, sparing of surrounding normal tissues, and quantitative, noninvasive longitudinal assessment of treatment response. Luciferase-expressing MiaPaCa-2 pancreatic carcinoma cells were orthotopically injected in nude mice. BLI was compared to pathologic tumor volume, and photon emission was assessed over time. BLI was correlated to positron emission tomography (PET)/computed tomography (CT) to estimate tumor dimensions. BLI and cone-beam CT (CBCT) were used to compare tumor centroid location and estimate setup error. BLI and CBCT fusion was performed to guide irradiation of tumors using the small animal radiation research platform (SARRP). DNA damage was assessed by γ-H2Ax staining. BLI was used to longitudinally monitor treatment response. Bioluminescence predicted tumor volume (R = 0.8984) and increased linearly as a function of time up to a 10-fold increase in tumor burden. BLI correlated with PET/CT and necropsy specimen in size (P < .05). Two-dimensional BLI centroid accuracy was 3.5 mm relative to CBCT. BLI-guided irradiated pancreatic tumors stained positively for γ-H2Ax, whereas surrounding normal tissues were spared. Longitudinal assessment of irradiated tumors with BLI revealed significant tumor growth delay of 20 days relative to controls. We have successfully applied the SARRP to a bioluminescent, orthotopic preclinical pancreas cancer model to noninvasively: 1) allow the identification of tumor burden before therapy, 2) facilitate image-guided focal radiation therapy, and 3) allow normalization of tumor burden and longitudinal assessment of treatment response.

  10. Coastal Thematic Exploitation Platform (C-TEP): An innovative and collaborative platform to facilitate Big Data coastal research

    Science.gov (United States)

    Tuohy, Eimear; Clerc, Sebastien; Politi, Eirini; Mangin, Antoine; Datcu, Mihai; Vignudelli, Stefano; Illuzzi, Diomede; Craciunescu, Vasile; Aspetsberger, Michael

    2017-04-01

    The Coastal Thematic Exploitation Platform (C-TEP) is an on-going European Space Agency (ESA) funded project to develop a web service dedicated to the observation of the coastal environment and to support coastal management and monitoring. For over 20 years ESA satellites have provided a wealth of environmental data. The availability of an ever increasing volume of environmental data from satellite remote sensing provides a unique opportunity for exploratory science and the development of coastal applications. However, the diversity and complexity of EO data available, the need for efficient data access, information extraction, data management and high spec processing tools pose major challenges to achieving its full potential in terms of Big Data exploitation. C-TEP will provide a new means to handle the technical challenges of the observation of coastal areas and contribute to improved understanding and decision-making with respect to coastal resources and environments. C-TEP will unlock coastal knowledge and innovation as a collaborative, virtual work environment providing access to a comprehensive database of coastal Earth Observation (EO) data, in-situ data, model data and the tools and processors necessary to fully exploit these vast and heterogeneous datasets. The cloud processing capabilities provided, allow users to perform heavy processing tasks through a user-friendly Graphical User Interface (GUI). A connection to the PEPS (Plateforme pour l'Exploitation des Produits Sentinel) archive will provide data from Sentinel missions 1, 2 and 3. Automatic comparison tools will be provided to exploit the in-situ datasets in synergy with EO data. In addition, users may develop, test and share their own advanced algorithms for the extraction of coastal information. Algorithm validation will be facilitated by the capabilities to compute statistics over long time-series. Finally, C-TEP subscription services will allow users to perform automatic monitoring of some key

  11. RMS: a platform for managing cross-disciplinary and multi-institutional research project collaboration.

    Science.gov (United States)

    Luo, Jake; Apperson-Hansen, Carolyn; Pelfrey, Clara M; Zhang, Guo-Qiang

    2014-11-30

    Cross-institutional cross-disciplinary collaboration has become a trend as researchers move toward building more productive and innovative teams for scientific research. Research collaboration is significantly changing the organizational structure and strategies used in the clinical and translational science domain. However, due to the obstacles of diverse administrative structures, differences in area of expertise, and communication barriers, establishing and managing a cross-institutional research project is still a challenging task. We address these challenges by creating an integrated informatics platform to reduce the barriers to biomedical research collaboration. The Request Management System (RMS) is an informatics infrastructure designed to transform a patchwork of expertise and resources into an integrated support network. The RMS facilitates investigators' initiation of new collaborative projects and supports the management of the collaboration process. In RMS, experts and their knowledge areas are categorized and managed structurally to provide consistent service. A role-based collaborative workflow is tightly integrated with domain experts and services to streamline and monitor the life-cycle of a research project. The RMS has so far tracked over 1,500 investigators with over 4,800 tasks. The research network based on the data collected in RMS illustrated that the investigators' collaborative projects increased close to 3 times from 2009 to 2012. Our experience with RMS indicates that the platform reduces barriers for cross-institutional collaboration of biomedical research projects. Building a new generation of infrastructure to enhance cross-disciplinary and multi-institutional collaboration has become an important yet challenging task. In this paper, we share the experience of developing and utilizing a collaborative project management system. The results of this study demonstrate that a web-based integrated informatics platform can facilitate and

  12. Global and Local Path Planning Study in a ROS-Based Research Platform for Autonomous Vehicles

    Directory of Open Access Journals (Sweden)

    Pablo Marin-Plaza

    2018-01-01

    Full Text Available The aim of this work is to integrate and analyze the performance of a path planning method based on Time Elastic Bands (TEB in real research platform based on Ackermann model. Moreover, it will be proved that all modules related to the navigation can coexist and work together to achieve the goal point without any collision. The study is done by analyzing the trajectory generated from global and local planners. The software prototyping tool is Robot Operating System (ROS from Open Source Robotics Foundation and the research platform is the iCab (Intelligent Campus Automobile from University Carlos III. This work has been validated from a test inside the campus where the iCab has performed the navigation between the starting point and the goal point without any collision. During the experiment, we proved the low sensitivity of the TEB method to variations of the vehicle model configuration and constraints.

  13. A method for establishing a long duration, stratospheric platform for astronomical research

    Science.gov (United States)

    Fesen, Robert; Brown, Yorke

    2015-10-01

    During certain times of the year at middle and low latitudes, winds in the upper stratosphere move in nearly the opposite direction than the wind in the lower stratosphere. Here we present a method for maintaining a high-altitude balloon platform in near station-keeping mode that utilizes this stratospheric wind shear. The proposed method places a balloon-borne science platform high in the stratosphere connected by a lightweight, high-strength tether to a tug vehicle located in the lower or middle stratosphere. Using aerodynamic control surfaces, wind-induced aerodynamic forces on the tug can be manipulated to counter the wind drag acting on the higher altitude science vehicle, thus controlling the upper vehicle's geographic location. We describe the general framework of this station-keeping method, some important properties required for the upper stratospheric science payload and lower tug platforms, and compare this station-keeping approach with the capabilities of a high altitude airship and conventional tethered aerostat approaches. We conclude by discussing the advantages of such a platform for a variety of missions with emphasis on astrophysical research.

  14. Central Vehicle Dynamics Control of the Robotic Research Platform ROboMObil

    OpenAIRE

    Bünte, Tilman; Ho, Lok Man; Satzger, Clemens; Brembeck, Jonathan

    2014-01-01

    The ROboMObil is DLR’s space-robotics driven by-wire electro-mobile research platform for mechatronic actuators, vehicle dynamics control, human machine interfaces, and autonomous driving (DLR = German Aerospace Center). Due to its four highly integrated identical Wheel Robots it exhibits an extraordinary manoeuvrability even allowing for driving sideward or rotating on the spot. Topics related to vehicle dynamics control are addressed in this article.

  15. Designing an Africa-EU research and innovation collaboration platform on climate change

    DEFF Research Database (Denmark)

    Tostensen, Arne; Monteverde Haakonsen, Jan; Hughes, Mike

    Climate change is arguably the most significant of a set of interconnected global challenges threatening water resources and food security. In particular, the relationship between water resources, food systems and climate change is tightly coupled, and improved food security under climate change...... this process more effective by developing a proposition for a platform to strengthen Africa-EU research and innovation collaboration on climate change....

  16. Mobile Phone Cognitive Bias Modification Research Platform for Substance Use Disorders: Protocol for a Feasibility Study.

    Science.gov (United States)

    Zhang, Melvyn; Ying, JiangBo; Song, Guo; Fung, Daniel Ss; Smith, Helen

    2018-06-12

    Cognitive biases refer to automatic attentional and interpretational tendencies, which could be retained by cognitive bias modification interventions. Cristea et al and Jones et al have published reviews (in 2016 and 2017 respectively) on the effectiveness of such interventions. The advancement of technologies such as electronic health (eHealth) and mobile health (mHealth) has led to them being harnessed for the delivery of cognitive bias modification. To date, at least eight studies have demonstrated the feasibility of mobile technologies for the delivery of cognitive bias modification. Most of the studies are limited to a description of the conventional cognitive bias modification methodology that has been adopted. None of the studies shared the developmental process for the methodology involved, such that future studies could adopt it in the cost-effective replication of such interventions. It is important to have a common platform that could facilitate the design and customization of cognitive bias modification interventions for a variety of psychiatric and addictive disorders. It is the aim of the current research protocol to describe the design of a research platform that allows for customization of cognitive bias modification interventions for addictive disorders. A multidisciplinary team of 2 addiction psychiatrists, a psychologist with expertise in cognitive bias modification, and a computer engineer, were involved in the development of the intervention. The proposed platform would comprise of a mobile phone version of the cognitive bias task which is controlled by a server that could customize the algorithm for the tasks and collate the reaction-time data in realtime. The server would also allow the researcher to program the specific set of images that will be present in the task. The mobile phone app would synchronize with the backend server in real-time. An open-sourced cross-platform gaming software from React Native was used in the current development

  17. Development of a Web-Based Visualization Platform for Climate Research Using Google Earth

    Science.gov (United States)

    Sun, Xiaojuan; Shen, Suhung; Leptoukh, Gregory G.; Wang, Panxing; Di, Liping; Lu, Mingyue

    2011-01-01

    Recently, it has become easier to access climate data from satellites, ground measurements, and models from various data centers, However, searching. accessing, and prc(essing heterogeneous data from different sources are very tim -consuming tasks. There is lack of a comprehensive visual platform to acquire distributed and heterogeneous scientific data and to render processed images from a single accessing point for climate studies. This paper. documents the design and implementation of a Web-based visual, interoperable, and scalable platform that is able to access climatological fields from models, satellites, and ground stations from a number of data sources using Google Earth (GE) as a common graphical interface. The development is based on the TCP/IP protocol and various data sharing open sources, such as OPeNDAP, GDS, Web Processing Service (WPS), and Web Mapping Service (WMS). The visualization capability of integrating various measurements into cE extends dramatically the awareness and visibility of scientific results. Using embedded geographic information in the GE, the designed system improves our understanding of the relationships of different elements in a four dimensional domain. The system enables easy and convenient synergistic research on a virtual platform for professionals and the general public, gr$tly advancing global data sharing and scientific research collaboration.

  18. GIFT-Cloud: A data sharing and collaboration platform for medical imaging research.

    Science.gov (United States)

    Doel, Tom; Shakir, Dzhoshkun I; Pratt, Rosalind; Aertsen, Michael; Moggridge, James; Bellon, Erwin; David, Anna L; Deprest, Jan; Vercauteren, Tom; Ourselin, Sébastien

    2017-02-01

    Clinical imaging data are essential for developing research software for computer-aided diagnosis, treatment planning and image-guided surgery, yet existing systems are poorly suited for data sharing between healthcare and academia: research systems rarely provide an integrated approach for data exchange with clinicians; hospital systems are focused towards clinical patient care with limited access for external researchers; and safe haven environments are not well suited to algorithm development. We have established GIFT-Cloud, a data and medical image sharing platform, to meet the needs of GIFT-Surg, an international research collaboration that is developing novel imaging methods for fetal surgery. GIFT-Cloud also has general applicability to other areas of imaging research. GIFT-Cloud builds upon well-established cross-platform technologies. The Server provides secure anonymised data storage, direct web-based data access and a REST API for integrating external software. The Uploader provides automated on-site anonymisation, encryption and data upload. Gateways provide a seamless process for uploading medical data from clinical systems to the research server. GIFT-Cloud has been implemented in a multi-centre study for fetal medicine research. We present a case study of placental segmentation for pre-operative surgical planning, showing how GIFT-Cloud underpins the research and integrates with the clinical workflow. GIFT-Cloud simplifies the transfer of imaging data from clinical to research institutions, facilitating the development and validation of medical research software and the sharing of results back to the clinical partners. GIFT-Cloud supports collaboration between multiple healthcare and research institutions while satisfying the demands of patient confidentiality, data security and data ownership. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  19. Advancing Translational Space Research Through Biospecimen Sharing: Amplified Impact of Studies Utilizing Analogue Space Platforms

    Science.gov (United States)

    Staten, B.; Moyer, E.; Vizir, V.; Gompf, H.; Hoban-Higgins, T.; Lewis, L.; Ronca, A.; Fuller, C. A.

    2016-01-01

    Biospecimen Sharing Programs (BSPs) have been organized by NASA Ames Research Center since the 1960s with the goal of maximizing utilization and scientific return from rare, complex and costly spaceflight experiments. BSPs involve acquiring otherwise unused biological specimens from primary space research experiments for distribution to secondary experiments. Here we describe a collaboration leveraging Ames expertise in biospecimen sharing to magnify the scientific impact of research informing astronaut health funded by the NASA Human Research Program (HRP) Human Health Countermeasures (HHC) Element. The concept expands biospecimen sharing to one-off ground-based studies utilizing analogue space platforms (e.g., Hindlimb Unloading (HLU), Artificial Gravity) for rodent experiments, thereby significantly broadening the range of research opportunities with translational relevance for protecting human health in space and on Earth.

  20. WiseEye: Next Generation Expandable and Programmable Camera Trap Platform for Wildlife Research.

    Directory of Open Access Journals (Sweden)

    Sajid Nazir

    Full Text Available The widespread availability of relatively cheap, reliable and easy to use digital camera traps has led to their extensive use for wildlife research, monitoring and public outreach. Users of these units are, however, often frustrated by the limited options for controlling camera functions, the generation of large numbers of images, and the lack of flexibility to suit different research environments and questions. We describe the development of a user-customisable open source camera trap platform named 'WiseEye', designed to provide flexible camera trap technology for wildlife researchers. The novel platform is based on a Raspberry Pi single-board computer and compatible peripherals that allow the user to control its functions and performance. We introduce the concept of confirmatory sensing, in which the Passive Infrared triggering is confirmed through other modalities (i.e. radar, pixel change to reduce the occurrence of false positives images. This concept, together with user-definable metadata, aided identification of spurious images and greatly reduced post-collection processing time. When tested against a commercial camera trap, WiseEye was found to reduce the incidence of false positive images and false negatives across a range of test conditions. WiseEye represents a step-change in camera trap functionality, greatly increasing the value of this technology for wildlife research and conservation management.

  1. Research on vehicles and cargos matching model based on virtual logistics platform

    Science.gov (United States)

    Zhuang, Yufeng; Lu, Jiang; Su, Zhiyuan

    2018-04-01

    Highway less than truckload (LTL) transportation vehicles and cargos matching problem is a joint optimization problem of typical vehicle routing and loading, which is also a hot issue of operational research. This article based on the demand of virtual logistics platform, for the problem of the highway LTL transportation, the matching model of the idle vehicle and the transportation order is set up and the corresponding genetic algorithm is designed. Then the algorithm is implemented by Java. The simulation results show that the solution is satisfactory.

  2. ISS External Payload Platform - a new opportunity for research in the space environment

    Science.gov (United States)

    Steimle, Christian; Pape, Uwe

    The International Space Station (ISS) is a widely accepted platform for research activities in low Earth orbit. To a wide extent these activities are conducted in the pressurised laboratories of the station and less in the outside environment. Suitable locations outside the ISS are rare, existing facilities fully booked for the coming years. To overcome this limitation, an external payload platform accessible for small size payloads on a commercial basis will be launched to the ISS and installed on the Japanese Experiment Module External Facility (JEM-EF) in the third quarter of 2014 and will be ready to be used by the scientific community on a fully commercial basis. The new External Payload Platform (EPP) and its opportunities and constraints assessed regarding future research activities on-board the ISS. The small size platform is realised in a cooperation between the companies NanoRacks, Astrium North America in the United States, and Airbus Defence and Space in Germany. The hardware allows the fully robotic installation and operation of payloads. In the nominal mission scenario payload items are installed not later than one year after the signature of the contract, stay in operation for 15 weeks, and can be returned to the scientist thereafter. Payload items are transported among the pressurised cargo usually delivered to the station with various supply vehicles. Due to the high frequency of flights and the flexibility of the vehicle manifests the risk of a delay in the payload readiness can be mitigated by delaying to the next flight opportunity which on average is available not more than two months later. The mission is extra-ordinarily fast and of low cost in comparison to traditional research conducted on-board the ISS and can fit into short-term funding cycles available on national and multi-national levels. The size of the payload items is limited by handling constraints on-board the ISS. Therefore, the standard experiment payload size is a multiple of a

  3. Evaluation of Variable Refrigerant Flow Systems Performance on Oak Ridge National Laboratory s Flexible Research Platform: Part 3 Simulation Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Im, Piljae [ORNL; Cho, Heejin [Mississippi State University (MSU); Kim, Dongsu [Mississippi State University (MSU); Cox, Sam [Mississippi State University (MSU)

    2016-08-01

    This report provides second-year project simulation results for the multi-year project titled “Evaluation of Variable Refrigeration Flow (VRF) system on Oak Ridge National Laboratory (ORNL)’s Flexible Research Platform (FRP).”

  4. A Binaural CI Research Platform for Oticon Medical SP/XP Implants Enabling ITD/ILD and Variable Rate Processing

    Science.gov (United States)

    Adiloğlu, K.; Herzke, T.

    2015-01-01

    We present the first portable, binaural, real-time research platform compatible with Oticon Medical SP and XP generation cochlear implants. The platform consists of (a) a pair of behind-the-ear devices, each containing front and rear calibrated microphones, (b) a four-channel USB analog-to-digital converter, (c) real-time PC-based sound processing software called the Master Hearing Aid, and (d) USB-connected hardware and output coils capable of driving two implants simultaneously. The platform is capable of processing signals from the four microphones simultaneously and producing synchronized binaural cochlear implant outputs that drive two (bilaterally implanted) SP or XP implants. Both audio signal preprocessing algorithms (such as binaural beamforming) and novel binaural stimulation strategies (within the implant limitations) can be programmed by researchers. When the whole research platform is combined with Oticon Medical SP implants, interaural electrode timing can be controlled on individual electrodes to within ±1 µs and interaural electrode energy differences can be controlled to within ±2%. Hence, this new platform is particularly well suited to performing experiments related to interaural time differences in combination with interaural level differences in real-time. The platform also supports instantaneously variable stimulation rates and thereby enables investigations such as the effect of changing the stimulation rate on pitch perception. Because the processing can be changed on the fly, researchers can use this platform to study perceptual changes resulting from different processing strategies acutely. PMID:26721923

  5. A Binaural CI Research Platform for Oticon Medical SP/XP Implants Enabling ITD/ILD and Variable Rate Processing.

    Science.gov (United States)

    Backus, B; Adiloğlu, K; Herzke, T

    2015-12-30

    We present the first portable, binaural, real-time research platform compatible with Oticon Medical SP and XP generation cochlear implants. The platform consists of (a) a pair of behind-the-ear devices, each containing front and rear calibrated microphones, (b) a four-channel USB analog-to-digital converter, (c) real-time PC-based sound processing software called the Master Hearing Aid, and (d) USB-connected hardware and output coils capable of driving two implants simultaneously. The platform is capable of processing signals from the four microphones simultaneously and producing synchronized binaural cochlear implant outputs that drive two (bilaterally implanted) SP or XP implants. Both audio signal preprocessing algorithms (such as binaural beamforming) and novel binaural stimulation strategies (within the implant limitations) can be programmed by researchers. When the whole research platform is combined with Oticon Medical SP implants, interaural electrode timing can be controlled on individual electrodes to within ±1 µs and interaural electrode energy differences can be controlled to within ±2%. Hence, this new platform is particularly well suited to performing experiments related to interaural time differences in combination with interaural level differences in real-time. The platform also supports instantaneously variable stimulation rates and thereby enables investigations such as the effect of changing the stimulation rate on pitch perception. Because the processing can be changed on the fly, researchers can use this platform to study perceptual changes resulting from different processing strategies acutely. © The Author(s) 2015.

  6. Research and Development of Target Recognition and Location Crawling Platform based on Binocular Vision

    Science.gov (United States)

    Xu, Weidong; Lei, Zhu; Yuan, Zhang; Gao, Zhenqing

    2018-03-01

    The application of visual recognition technology in industrial robot crawling and placing operation is one of the key tasks in the field of robot research. In order to improve the efficiency and intelligence of the material sorting in the production line, especially to realize the sorting of the scattered items, the robot target recognition and positioning crawling platform based on binocular vision is researched and developed. The images were collected by binocular camera, and the images were pretreated. Harris operator was used to identify the corners of the images. The Canny operator was used to identify the images. Hough-chain code recognition was used to identify the images. The target image in the image, obtain the coordinates of each vertex of the image, calculate the spatial position and posture of the target item, and determine the information needed to capture the movement and transmit it to the robot control crawling operation. Finally, In this paper, we use this method to experiment the wrapping problem in the express sorting process The experimental results show that the platform can effectively solve the problem of sorting of loose parts, so as to achieve the purpose of efficient and intelligent sorting.

  7. Platform Constellations

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2016-01-01

    This research paper presents an initial attempt to introduce and explain the emergence of new phenomenon, which we refer to as platform constellations. Functioning as highly modular systems, the platform constellations are collections of highly connected platforms which co-exist in parallel and a......’ acquisition and users’ engagement rates as well as unlock new sources of value creation and diversify revenue streams....

  8. Adaptations of Personal Health Record Platform for Medical Research on Chronic Diseases

    Directory of Open Access Journals (Sweden)

    A. Krukowski

    2015-05-01

    Full Text Available The article reports on experiences in e-Health platforms and services for supporting medical research into the causes and relationships among physiological parameters and health problems concerning different chronic diseases. The Personal Health Record (PHR is a way of standardizing electronic management of medical information between patients and their physicians, including medical bodies collaborating in providing integrated medical care services. We describe roles and aims behind electronic health records, follow with applicable legal and standardizations frameworks and relevant European activities, leading to the presentation of common commercial and open-source implementations of such systems, concluding with the indication of specific adaptations enabling a use of stored personal health data for scientific research into causes and evaluation of chronic illnesses. We describe ethical and privacy concerns that are relevant to using and exchanging electronic health information.

  9. Storylines as an alternative method to communicate river research via a knowledge platform

    Science.gov (United States)

    Cortes Arevalo, Juliette; Verbrugge, Laura N. H.; den Haan, Robert Jan; Baart, Fedor; Hulscher, Suzanne J. M. H.; van der Voort, Mascha C.

    2017-04-01

    Sustainable river management relies on diverse and multi-faceted knowledge from fundamental and applied research. Communicating the context, added value and potential use of river research to actors working in multiple disciplines or organizations is challenging. RiverCare is a research programme studying the mid-term effects of innovative river interventions in the Netherlands. Effective communication between researchers and potential users of scientific information, such as water professionals, requires an interactive, two-way communication approach. As part of the communication strategy, we are designing a knowledge platform to provide access to, explain and gather feedback about the potential use of results from water professionals. The knowledge platform is a combination of online services including: a content management system in which storylines are the main component; a data repository to the underlying research data and; hyperlinks to existing online sites that present our results via short news articles. Storylines engage water professionals via experiences or stories of river management actors to explain research outputs instead of or in addition to more technical means such as scientific papers and reports. The use of storylines enables us to explain research outcomes in a way that is captivating and easily understood by a multi-disciplinary audience. To explore its usefulness as communication approach, we developed a storyline example for research about stakeholder perceptions of a re-landscaping intervention in the Waal river in the Netherlands. The storyline's layout consisted of a menu outline and three tabs: (1) storyline's content; (2) contact details; and (3) links to available resources or related publications. The storyline's content was divided in four sections including subsections to navigate. Each section had a heading statement or question to engage users: "Imagine this!"; "What matters? Places matter to people"; "Surveying people

  10. SmartR: an open-source platform for interactive visual analytics for translational research data.

    Science.gov (United States)

    Herzinger, Sascha; Gu, Wei; Satagopam, Venkata; Eifes, Serge; Rege, Kavita; Barbosa-Silva, Adriano; Schneider, Reinhard

    2017-07-15

    In translational research, efficient knowledge exchange between the different fields of expertise is crucial. An open platform that is capable of storing a multitude of data types such as clinical, pre-clinical or OMICS data combined with strong visual analytical capabilities will significantly accelerate the scientific progress by making data more accessible and hypothesis generation easier. The open data warehouse tranSMART is capable of storing a variety of data types and has a growing user community including both academic institutions and pharmaceutical companies. tranSMART, however, currently lacks interactive and dynamic visual analytics and does not permit any post-processing interaction or exploration. For this reason, we developed SmartR , a plugin for tranSMART, that equips the platform not only with several dynamic visual analytical workflows, but also provides its own framework for the addition of new custom workflows. Modern web technologies such as D3.js or AngularJS were used to build a set of standard visualizations that were heavily improved with dynamic elements. The source code is licensed under the Apache 2.0 License and is freely available on GitHub: https://github.com/transmart/SmartR . reinhard.schneider@uni.lu. Supplementary data are available at Bioinformatics online. © The Author(s) 2017. Published by Oxford University Press.

  11. An FPGA Scalable Software Defined Radio Platform Design for Educational and Research Purposes

    Directory of Open Access Journals (Sweden)

    Marcos Hervás

    2016-06-01

    Full Text Available In a digital modem design, the integration of the Analog to Digital Converters (ADC and Digital to Analog Converters (DAC with the core processor is usually a major issue for the designer. In this paper an FPGA scalable Software Defined Radio platform based on a Spartan-6 as a control unit is presented, developed for both educational and research purposes, which can fit the different application requirements in terms of analog front-end performance, processing unit and cost. The resolution and sampling frequency of the analog front-end are its main adjustable parameters. The processing core requirements involve the FPGA and the communication ports. A multidisciplinary working group was required to design a high performance system for both analog front-end and digital processing core in terms of signal integrity and electromagnetic compatibility. The platform has 5 different peripheral ports ranging from 16 kbps to 2.5 Gbps. The communication ports allow our students to develop a high range of applications for both on-site and online courses applying teaching methodology based on learning by doing using a real system to help them to reach other transversal skills.

  12. The scheme and research of TV series multidimensional comprehensive evaluation on cross-platform

    Science.gov (United States)

    Chai, Jianping; Bai, Xuesong; Zhou, Hongjun; Yin, Fulian

    2016-10-01

    As for shortcomings of the comprehensive evaluation system on traditional TV programs such as single data source, ignorance of new media as well as the high time cost and difficulty of making surveys, a new evaluation of TV series is proposed in this paper, which has a perspective in cross-platform multidimensional evaluation after broadcasting. This scheme considers the data directly collected from cable television and the Internet as research objects. It's based on TOPSIS principle, after preprocessing and calculation of the data, they become primary indicators that reflect different profiles of the viewing of TV series. Then after the process of reasonable empowerment and summation by the six methods(PCA, AHP, etc.), the primary indicators form the composite indices on different channels or websites. The scheme avoids the inefficiency and difficulty of survey and marking; At the same time, it not only reflects different dimensions of viewing, but also combines TV media and new media, completing the multidimensional comprehensive evaluation of TV series on cross-platform.

  13. Application research of cloud computing in emergency system platform of nuclear accidents

    International Nuclear Information System (INIS)

    Zhang Yan; Yue Huiguo; Lin Quanyi; Yue Feng

    2013-01-01

    This paper described the key technology of the concept of cloud computing, service type and implementation methods. Combined with the upgrade demand of nuclear accident emergency system platform, the paper also proposed the application design of private cloud computing platform, analyzed safety of cloud platform and the characteristics of cloud disaster recovery. (authors)

  14. The Data Platform for Climate Research and Action: Introducing Climate Watch

    Science.gov (United States)

    Hennig, R. J.; Ge, M.; Friedrich, J.; Lebling, K.; Carlock, G.; Arcipowska, A.; Mangan, E.; Biru, H.; Tankou, A.; Chaudhury, M.

    2017-12-01

    The Paris Agreement, adopted through Decision 1/CP.21, brings all nations together to take on ambitious efforts to combat climate change. Open access to climate data supporting climate research, advancing knowledge, and informing decision making is key to encourage and strengthen efforts of stakeholders at all levels to address and respond to effects of climate change. Climate Watch is a robust online data platform developed in response to the urgent needs of knowledge and tools to empower climate research and action, including those of researchers, policy makers, the private sector, civil society, and all other non-state actors. Building on the rapid growing technology of open data and information sharing, Climate Watch is equipped with extensive amount of climate data, informative visualizations, concise yet efficient user interface, and connection to resources users need to gather insightful information on national and global progress towards delivering on the objective of the Convention and the Paris Agreement. Climate Watch brings together hundreds of quantitative and qualitative indicators for easy explore, visualize, compare, download at global, national, and sectoral levels: Greenhouse gas (GHG) emissions for more than 190 countries over the1850-2014 time period, covering all seven Kyoto Gases following IPCC source/sink categories; Structured information on over 150 NDCs facilitating the clarity, understanding and transparency of countries' contributions to address climate change; Over 6500 identified linkages between climate actions in NDCs across the 169 targets of the sustainable development goals (SDG); Over 200 indicators describing low carbon pathways from models and scenarios by integrated assessment models (IAMs) and national sources; and Data on vulnerability and risk, policies, finance, and many more. Climate Watch platform is developed as part of the broader efforts within the World Resources Institute, the NDC Partnership, and in collaboration

  15. MyGeoHub: A Collaborative Geospatial Research and Education Platform

    Science.gov (United States)

    Kalyanam, R.; Zhao, L.; Biehl, L. L.; Song, C. X.; Merwade, V.; Villoria, N.

    2017-12-01

    Scientific research is increasingly collaborative and globally distributed; research groups now rely on web-based scientific tools and data management systems to simplify their day-to-day collaborative workflows. However, such tools often lack seamless interfaces, requiring researchers to contend with manual data transfers, annotation and sharing. MyGeoHub is a web platform that supports out-of-the-box, seamless workflows involving data ingestion, metadata extraction, analysis, sharing and publication. MyGeoHub is built on the HUBzero cyberinfrastructure platform and adds general-purpose software building blocks (GABBs), for geospatial data management, visualization and analysis. A data management building block iData, processes geospatial files, extracting metadata for keyword and map-based search while enabling quick previews. iData is pervasive, allowing access through a web interface, scientific tools on MyGeoHub or even mobile field devices via a data service API. GABBs includes a Python map library as well as map widgets that in a few lines of code, generate complete geospatial visualization web interfaces for scientific tools. GABBs also includes powerful tools that can be used with no programming effort. The GeoBuilder tool provides an intuitive wizard for importing multi-variable, geo-located time series data (typical of sensor readings, GPS trackers) to build visualizations supporting data filtering and plotting. MyGeoHub has been used in tutorials at scientific conferences and educational activities for K-12 students. MyGeoHub is also constantly evolving; the recent addition of Jupyter and R Shiny notebook environments enable reproducible, richly interactive geospatial analyses and applications ranging from simple pre-processing to published tools. MyGeoHub is not a monolithic geospatial science gateway, instead it supports diverse needs ranging from just a feature-rich data management system, to complex scientific tools and workflows.

  16. Creating a Knowledge Translation Platform: nine lessons from the Zambia Forum for Health Research

    Directory of Open Access Journals (Sweden)

    Kasonde Joseph M

    2012-10-01

    Full Text Available Abstract The concept of the Knowledge Translation Platform (KTP provides cohesion and leadership for national–level knowledge translation efforts. In this review, we discuss nine key lessons documenting the experience of the Zambia Forum for Health Research, primarily to inform and exchange experience with the growing community of African KTPs. Lessons from ZAMFOHR’s organizational development include the necessity of selecting a multi-stakeholder and -sectoral Board of Directors; performing comprehensive situation analyses to understand not only the prevailing research-and-policy dynamics but a precise operational niche; and selecting a leader that bridges the worlds of research and policy. Programmatic lessons include focusing on building the capacity of both policy-makers and researchers; building a database of local evidence and national-level actors involved in research and policy; and catalyzing work in particular issue areas by identifying leaders from the research community, creating policy-maker demand for research evidence, and fostering the next generation by mentoring both up-and-coming researchers and policy–makers. Ultimately, ZAMFOHR’s experience shows that an African KTP must pay significant attention to its organizational details. A KTP must also invest in the skill base of the wider community and, more importantly, of its own staff. Given the very real deficit of research-support skills in most low-income countries – in synthesis, in communications, in brokering, in training – a KTP must spend significant time and resources in building these types of in-house expertise. And lastly, the role of networking cannot be underestimated. As a fully-networked KTP, ZAMFOHR has benefited from the innovations of other KTPs, from funding opportunities and partnerships, and from invaluable technical support from both African and northern colleagues.

  17. Intelligent tools for building a scientific information platform from research to implementation

    CERN Document Server

    Skonieczny, Łukasz; Rybiński, Henryk; Kryszkiewicz, Marzena; Niezgódka, Marek

    2014-01-01

    This book is a selection of results obtained within three years of research performed under SYNAT—a nation-wide scientific project aiming at creating an infrastructure for scientific content storage and sharing for academia, education and open knowledge society in Poland. The book is intended to be the last of the series related to the SYNAT project. The previous books, titled “Intelligent Tools for Building a Scientific Information Platform” and “Intelligent Tools for Building a Scientific Information Platform: Advanced Architectures and Solutions”, were published as volumes 390 and 467 in Springer's Studies in Computational Intelligence. Its contents is based on the SYNAT 2013 Workshop held in Warsaw. The papers included in this volume present an overview and insight into information retrieval, repository systems, text processing, ontology-based systems, text mining, multimedia data processing and advanced software engineering, addressing the problems of implementing intelligent tools for building...

  18. Platform for systems medicine research and diagnostic applications in psychotic disorders-The METSY project

    DEFF Research Database (Denmark)

    Frank, Elisabeth; Maier, Dieter; Pajula, Juha

    2018-01-01

    with detailed metabolic characterisation and multi-variate network analysis is essential in order to identify how lipid dysregulation may contribute to psychotic disorders. A decision support system, integrating clinical, neuropsychological and neuroimaging data, was also developed in order to aid clinical......Psychotic disorders are associated with metabolic abnormalities including alterations in glucose and lipid metabolism. A major challenge in the treatment of psychosis is to identify patients with vulnerable metabolic profiles who may be at risk of developing cardiometabolic co...... these endocannabinoid abnormalities relate to metabolic changes in psychosis. Here we review recent research in the field of metabolic co-morbidities in psychotic disorders as well as the methods to study them and potential links to the endocannabinoid system. We also describe the bioinformatics platforms developed...

  19. Globus Nexus: A Platform-as-a-Service Provider of Research Identity, Profile, and Group Management.

    Science.gov (United States)

    Chard, Kyle; Lidman, Mattias; McCollam, Brendan; Bryan, Josh; Ananthakrishnan, Rachana; Tuecke, Steven; Foster, Ian

    2016-03-01

    Globus Nexus is a professionally hosted Platform-as-a-Service that provides identity, profile and group management functionality for the research community. Many collaborative e-Science applications need to manage large numbers of user identities, profiles, and groups. However, developing and maintaining such capabilities is often challenging given the complexity of modern security protocols and requirements for scalable, robust, and highly available implementations. By outsourcing this functionality to Globus Nexus, developers can leverage best-practice implementations without incurring development and operations overhead. Users benefit from enhanced capabilities such as identity federation, flexible profile management, and user-oriented group management. In this paper we present Globus Nexus, describe its capabilities and architecture, summarize how several e-Science applications leverage these capabilities, and present results that characterize its scalability, reliability, and availability.

  20. Globus Nexus: A Platform-as-a-Service provider of research identity, profile, and group management

    Energy Technology Data Exchange (ETDEWEB)

    Chard, Kyle; Lidman, Mattias; McCollam, Brendan; Bryan, Josh; Ananthakrishnan, Rachana; Tuecke, Steven; Foster, Ian

    2016-03-01

    Globus Nexus is a professionally hosted Platform-as-a-Service that provides identity, profile and group management functionality for the research community. Many collaborative e-Science applications need to manage large numbers of user identities, profiles, and groups. However, developing and maintaining such capabilities is often challenging given the complexity of modern security protocols and requirements for scalable, robust, and highly available implementations. By outsourcing this functionality to Globus Nexus, developers can leverage best-practice implementations without incurring development and operations overhead. Users benefit from enhanced capabilities such as identity federation, flexible profile management, and user-oriented group management. In this paper we present Globus Nexus, describe its capabilities and architecture, summarize how several e-Science applications leverage these capabilities, and present results that characterize its scalability, reliability, and availability.

  1. The VIPER project (Visualization Integration Platform for Exploration Research): a biologically inspired autonomous reconfigurable robotic platform for diverse unstructured environments

    Science.gov (United States)

    Schubert, Oliver J.; Tolle, Charles R.

    2004-09-01

    Over the last decade the world has seen numerous autonomous vehicle programs. Wheels and track designs are the basis for many of these vehicles. This is primarily due to four main reasons: a vast preexisting knowledge base for these designs, energy efficiency of power sources, scalability of actuators, and the lack of control systems technologies for handling alternate highly complex distributed systems. Though large efforts seek to improve the mobility of these vehicles, many limitations still exist for these systems within unstructured environments, e.g. limited mobility within industrial and nuclear accident sites where existing plant configurations have been extensively changed. These unstructured operational environments include missions for exploration, reconnaissance, and emergency recovery of objects within reconfigured or collapsed structures, e.g. bombed buildings. More importantly, these environments present a clear and present danger for direct human interactions during the initial phases of recovery operations. Clearly, the current classes of autonomous vehicles are incapable of performing in these environments. Thus the next generation of designs must include highly reconfigurable and flexible autonomous robotic platforms. This new breed of autonomous vehicles will be both highly flexible and environmentally adaptable. Presented in this paper is one of the most successful designs from nature, the snake-eel-worm (SEW). This design implements shape memory alloy (SMA) actuators which allow for scaling of the robotic SEW designs from sub-micron scale to heavy industrial implementations without major conceptual redesigns as required in traditional hydraulic, pneumatic, or motor driven systems. Autonomous vehicles based on the SEW design posses the ability to easily move between air based environments and fluid based environments with limited or no reconfiguration. Under a SEW designed vehicle, one not only achieves vastly improved maneuverability within a

  2. The National Cohort of Dairy Farms--a data collection platform for mastitis research in Canada.

    Science.gov (United States)

    Reyher, K K; Dufour, S; Barkema, H W; Des Côteaux, L; Devries, T J; Dohoo, I R; Keefe, G P; Roy, J-P; Scholl, D T

    2011-03-01

    Costs and feasibility of extensive sample collection and processing are major obstacles to mastitis epidemiology research. Studies are often consequentially limited, and fundamental mastitis researchers rarely have the opportunity to conduct their work in epidemiologically valid populations. To mitigate these limitations, the Canadian Bovine Mastitis Research Network has optimized research funds by creating a data collection platform to provide epidemiologically meaningful data for several simultaneous research endeavors. This platform consists of a National Cohort of Dairy Farms (NCDF), Mastitis Laboratory Network, and Mastitis Pathogen Culture Collection. This paper describes the implementation and operation of the NCDF, explains its sampling protocols and data collection, and documents characteristics, strengths and limitations of these data for current and potential users. The NCDF comprises 91 commercial dairy farms in 6 provinces sampled over a 2-yr period. Primarily Holstein-Friesian herds participating in Dairy Herd Improvement milk recording were selected in order to achieve a uniform distribution among 3 strata of bulk tank somatic cell counts and to reflect regional proportions of freestall housing systems. Standardized protocols were implemented for repeated milk samplings on clinical mastitis cases, fresh and randomly selected lactating cows, and cows at dry-off and after calving. Just fewer than 133,000 milk samples were collected. Demographic and production data were recorded at individual cow and farm levels. Health management data are documented and extensive questionnaire data detailing farm management and cleanliness information are also captured. The Laboratory Network represents coordinated regional mastitis bacteriology laboratories using standardized procedures. The Culture Collection archives isolates recovered from intramammary infections of cows in the NCDF and contains over 16,500 isolates, all epidemiologically cross-referenced between

  3. "Where On Mars?": An Open Planetary Mapping Platform for Researchers, Educators, and the General Public

    Science.gov (United States)

    Manaud, Nicolas; Carter, John; Boix, Oriol

    2016-10-01

    The "Where On Mars?" project is essentially the evolution of an existing outreach product developed in collaboration between ESA and CartoDB; an interactive map visualisation of the ESA's ExoMars Rover candidate landing sites (whereonmars.co). Planetary imagery data and maps are increasingly produced by the scientific community, and shared typically as images, in scientific publications, presentations or public outreach websites. However, this media lacks of interactivity and contextual information available for further exploration, making it difficult for any audience to relate one location-based information to another. We believe that interactive web maps are a powerful way of telling stories, engaging with and educating people who, over the last decade, have become familiar with tools such as Google Maps. A few planetary web maps exist but they are either too complex for non-experts, or are closed-systems that do not allows anyone to publish and share content. The long-term vision for the project is to provide researchers, communicators, educators and a worldwide public with an open planetary mapping and social platform enabling them to create, share, communicate and consume research-based content. We aim for this platform to become the reference website everyone will go to learn about Mars and other planets in our Solar System; just like people head to Google Maps to find their bearings or any location-based information. The driver is clearly to create for people an emotional connection with Mars. The short-term objectives for the project are (1) to produce and curate an open repository of basemaps, geospatial data sets, map visualisations, and story maps; (2) to develop a beautifully crafted and engaging interactive map of Mars. Based on user-generated content, the underlying framework should (3) make it easy to create and share additional interactive maps telling specific stories.

  4. VASIR: An Open-Source Research Platform for Advanced Iris Recognition Technologies.

    Science.gov (United States)

    Lee, Yooyoung; Micheals, Ross J; Filliben, James J; Phillips, P Jonathon

    2013-01-01

    The performance of iris recognition systems is frequently affected by input image quality, which in turn is vulnerable to less-than-optimal conditions due to illuminations, environments, and subject characteristics (e.g., distance, movement, face/body visibility, blinking, etc.). VASIR (Video-based Automatic System for Iris Recognition) is a state-of-the-art NIST-developed iris recognition software platform designed to systematically address these vulnerabilities. We developed VASIR as a research tool that will not only provide a reference (to assess the relative performance of alternative algorithms) for the biometrics community, but will also advance (via this new emerging iris recognition paradigm) NIST's measurement mission. VASIR is designed to accommodate both ideal (e.g., classical still images) and less-than-ideal images (e.g., face-visible videos). VASIR has three primary modules: 1) Image Acquisition 2) Video Processing, and 3) Iris Recognition. Each module consists of several sub-components that have been optimized by use of rigorous orthogonal experiment design and analysis techniques. We evaluated VASIR performance using the MBGC (Multiple Biometric Grand Challenge) NIR (Near-Infrared) face-visible video dataset and the ICE (Iris Challenge Evaluation) 2005 still-based dataset. The results showed that even though VASIR was primarily developed and optimized for the less-constrained video case, it still achieved high verification rates for the traditional still-image case. For this reason, VASIR may be used as an effective baseline for the biometrics community to evaluate their algorithm performance, and thus serves as a valuable research platform.

  5. “Modular Biospheres” New testbed platforms for public environmental education and research

    Science.gov (United States)

    Nelson, M.; Dempster, W. F.; Allen, J. P.

    This paper will review the potential of a relatively new type of testbed platform for environmental education and research because of the unique advantages resulting from their material closure and separation from the outside environment. These facilities which we term "modular biospheres", have emerged from research centered on space life support research but offer a wider range of application. Examples of this type of facility include the Bios-3 facility in Russia, the Japanese CEEF (Closed Ecological Experiment Facility), the NASA Kennedy Space Center Breadboard facility, the Biosphere 2 Test Module and the Laboratory Biosphere. Modular biosphere facilities offer unique research and public real-time science education opportunities. Ecosystem behavior can be studied since initial state conditions can be precisely specified and tracked over different ranges of time. With material closure (apart from very small air exchange rate which can be determined), biogeochemical cycles between soil and soil microorganisms, water, plants, and atmosphere can be studied in detail. Such studies offer a major advance from studies conducted with phytotrons which because of their small size, limit the number of organisms to a very small number, and which crucially do not have a high degree of atmospheric, water and overall material closure. Modular biospheres take advantage of the unique properties of closure, as representing a distinct system "metabolism" and therefore are essentially a "mini-world". Though relatively large in comparison with most phytotrons and ecological microcosms, which are now standard research and educational tools, modular biospheres are small enough that they can be economically reconfigured to reflect a changing research agenda. Some design elements include lighting via electric lights and/or sunlight, hydroponic or soil substrate for plants, opaque or glazed structures, and variable volume chambers or other methods to handle atmospheric pressure

  6. NEON's Mobile Deployment Platform: A research tool for integrating ecological processes across scales

    Science.gov (United States)

    Sanclements, M.

    2016-12-01

    Here we provide an update on construction of the five NEON Mobile Deployment Platforms (MDPs) as well as a description of the infrastructure and sensors available to researchers in the near future. Additionally, we include information (i.e. timelines and procedures) on requesting MDPs for PI led projects. The MDPs will provide the means to observe stochastic or spatially important events, gradients, or quantities that cannot be reliably observed using fixed location sampling (e.g. fires and floods). Due to the transient temporal and spatial nature of such events, the MDPs are designed to accommodate rapid deployment for time periods up to 1 year. Broadly, the MDPs are comprised of infrastructure and instrumentation capable of functioning individually or in conjunction with one another to support observations of ecological change, as well as education, training and outreach. More specifically, the MDPs include the capability to make tower based measures of ecosystem exchange, radiation, and precipitation in conjunction with baseline soils data such as CO2 flux, and soil temperature and moisture. An aquatics module is also available with the MDP to facilitate research integrating terrestrial and aquatic processes. Ultimately, the NEON MDPs provides a tool for linking PI led research to the continental scale data sets collected by NEON.

  7. Space Science Cloud: a Virtual Space Science Research Platform Based on Cloud Model

    Science.gov (United States)

    Hu, Xiaoyan; Tong, Jizhou; Zou, Ziming

    Through independent and co-operational science missions, Strategic Pioneer Program (SPP) on Space Science, the new initiative of space science program in China which was approved by CAS and implemented by National Space Science Center (NSSC), dedicates to seek new discoveries and new breakthroughs in space science, thus deepen the understanding of universe and planet earth. In the framework of this program, in order to support the operations of space science missions and satisfy the demand of related research activities for e-Science, NSSC is developing a virtual space science research platform based on cloud model, namely the Space Science Cloud (SSC). In order to support mission demonstration, SSC integrates interactive satellite orbit design tool, satellite structure and payloads layout design tool, payload observation coverage analysis tool, etc., to help scientists analyze and verify space science mission designs. Another important function of SSC is supporting the mission operations, which runs through the space satellite data pipelines. Mission operators can acquire and process observation data, then distribute the data products to other systems or issue the data and archives with the services of SSC. In addition, SSC provides useful data, tools and models for space researchers. Several databases in the field of space science are integrated and an efficient retrieve system is developing. Common tools for data visualization, deep processing (e.g., smoothing and filtering tools), analysis (e.g., FFT analysis tool and minimum variance analysis tool) and mining (e.g., proton event correlation analysis tool) are also integrated to help the researchers to better utilize the data. The space weather models on SSC include magnetic storm forecast model, multi-station middle and upper atmospheric climate model, solar energetic particle propagation model and so on. All the services above-mentioned are based on the e-Science infrastructures of CAS e.g. cloud storage and

  8. qPortal: A platform for data-driven biomedical research.

    Science.gov (United States)

    Mohr, Christopher; Friedrich, Andreas; Wojnar, David; Kenar, Erhan; Polatkan, Aydin Can; Codrea, Marius Cosmin; Czemmel, Stefan; Kohlbacher, Oliver; Nahnsen, Sven

    2018-01-01

    Modern biomedical research aims at drawing biological conclusions from large, highly complex biological datasets. It has become common practice to make extensive use of high-throughput technologies that produce big amounts of heterogeneous data. In addition to the ever-improving accuracy, methods are getting faster and cheaper, resulting in a steadily increasing need for scalable data management and easily accessible means of analysis. We present qPortal, a platform providing users with an intuitive way to manage and analyze quantitative biological data. The backend leverages a variety of concepts and technologies, such as relational databases, data stores, data models and means of data transfer, as well as front-end solutions to give users access to data management and easy-to-use analysis options. Users are empowered to conduct their experiments from the experimental design to the visualization of their results through the platform. Here, we illustrate the feature-rich portal by simulating a biomedical study based on publically available data. We demonstrate the software's strength in supporting the entire project life cycle. The software supports the project design and registration, empowers users to do all-digital project management and finally provides means to perform analysis. We compare our approach to Galaxy, one of the most widely used scientific workflow and analysis platforms in computational biology. Application of both systems to a small case study shows the differences between a data-driven approach (qPortal) and a workflow-driven approach (Galaxy). qPortal, a one-stop-shop solution for biomedical projects offers up-to-date analysis pipelines, quality control workflows, and visualization tools. Through intensive user interactions, appropriate data models have been developed. These models build the foundation of our biological data management system and provide possibilities to annotate data, query metadata for statistics and future re-analysis on

  9. Design and research on the platform of network manufacture product electronic trading

    Science.gov (United States)

    Zhou, Zude; Liu, Quan; Jiang, Xuemei

    2003-09-01

    With the rapid globalization of market and business, E-trading affects every manufacture enterprise. However, the security of network manufacturing products of transmission on Internet is very important. In this paper we discussed the protocol of fair exchange and platform for network manufacture products E-trading based on fair exchange protocol and digital watermarking techniques. The platform realized reliable and copyright protection.

  10. SeqHound: biological sequence and structure database as a platform for bioinformatics research

    Directory of Open Access Journals (Sweden)

    Dumontier Michel

    2002-10-01

    Full Text Available Abstract Background SeqHound has been developed as an integrated biological sequence, taxonomy, annotation and 3-D structure database system. It provides a high-performance server platform for bioinformatics research in a locally-hosted environment. Results SeqHound is based on the National Center for Biotechnology Information data model and programming tools. It offers daily updated contents of all Entrez sequence databases in addition to 3-D structural data and information about sequence redundancies, sequence neighbours, taxonomy, complete genomes, functional annotation including Gene Ontology terms and literature links to PubMed. SeqHound is accessible via a web server through a Perl, C or C++ remote API or an optimized local API. It provides functionality necessary to retrieve specialized subsets of sequences, structures and structural domains. Sequences may be retrieved in FASTA, GenBank, ASN.1 and XML formats. Structures are available in ASN.1, XML and PDB formats. Emphasis has been placed on complete genomes, taxonomy, domain and functional annotation as well as 3-D structural functionality in the API, while fielded text indexing functionality remains under development. SeqHound also offers a streamlined WWW interface for simple web-user queries. Conclusions The system has proven useful in several published bioinformatics projects such as the BIND database and offers a cost-effective infrastructure for research. SeqHound will continue to develop and be provided as a service of the Blueprint Initiative at the Samuel Lunenfeld Research Institute. The source code and examples are available under the terms of the GNU public license at the Sourceforge site http://sourceforge.net/projects/slritools/ in the SLRI Toolkit.

  11. Systems Biology-Based Platforms to Accelerate Research of Emerging Infectious Diseases.

    Science.gov (United States)

    Oh, Soo Jin; Choi, Young Ki; Shin, Ok Sarah

    2018-03-01

    Emerging infectious diseases (EIDs) pose a major threat to public health and security. Given the dynamic nature and significant impact of EIDs, the most effective way to prevent and protect against them is to develop vaccines in advance. Systems biology approaches provide an integrative way to understand the complex immune response to pathogens. They can lead to a greater understanding of EID pathogenesis and facilitate the evaluation of newly developed vaccine-induced immunity in a timely manner. In recent years, advances in high throughput technologies have enabled researchers to successfully apply systems biology methods to analyze immune responses to a variety of pathogens and vaccines. Despite recent advances, computational and biological challenges impede wider application of systems biology approaches. This review highlights recent advances in the fields of systems immunology and vaccinology, and presents ways that systems biology-based platforms can be applied to accelerate a deeper understanding of the molecular mechanisms of immunity against EIDs. © Copyright: Yonsei University College of Medicine 2018.

  12. Do mature innovation platforms make a difference in agricultural research for development? a meta-analysis of case studies

    NARCIS (Netherlands)

    Schut, Marc; Cadilhon, Jean-Joseph; Misiko, Michael; Dror, Iddo

    2018-01-01

    Innovation Platforms (IPs) have become a popular vehicle in agricultural research for development (AR4D). The IP promise is that integrating scientific and local knowledge results in innovations that can have impact at scale. Many studies have uncovered how IPs work in various countries, value

  13. How scientific visions matter: insights from three long-term socio-ecological research (LTSER) platforms under construction in Europe

    NARCIS (Netherlands)

    Mauz, I.; Peltola, T.; Granjou, C.; Bommel, van S.; Buijs, A.E.

    2012-01-01

    Long-Term Socio-Ecological Research (LTSER) has been introduced to change the current approach to ecology and turn it into a big science. LTSER Platforms are currently being created across Europe. They are expected to enhance ecology's capacity to produce useful knowledge for facing global

  14. Technical Research on the Electric Power Big Data Platform of Smart Grid

    OpenAIRE

    Ruiguang MA; Haiyan Wang; Quanming Zhang; Yuan Liang

    2017-01-01

    Through elaborating on the associated relationship among electric power big data, cloud computing and smart grid, this paper put forward general framework of electric power big data platform based on the smart grid. The general framework of the platform is divided into five layers, namely data source layer, data integration and storage layer, data processing and scheduling layer, data analysis layer and application layer. This paper makes in-depth exploration and studies the integrated manage...

  15. Biochem-Env, a platform of environmental biochemistry for research in ecology and ecotoxicology

    OpenAIRE

    Grondin, Virginie; Nelieu, Sylvie; Crouzet, Olivier; Hedde, Mickaël; Mougin, Christian

    2016-01-01

    The consortium AnaEE-France (http://www.anaee-s.fr) aims at understanding and predicting the biodiversity and ecosystems dynamics in a context of global change. It will allow improving the understanding of biotic processes/environment interactions, mobilizing experimental and modelling platforms devoted to the biology of continental ecosystems, both terrestrial and aquatic. In this context, the objectives of the platform Biochem-Env (http://www.biochemenv.fr) are to provide skills and innovat...

  16. Mission Specific Platforms: Past achievements and future developments in European led ocean research drilling.

    Science.gov (United States)

    Cotterill, Carol; McInroy, David; Stevenson, Alan

    2013-04-01

    Mission Specific Platform (MSP) expeditions are operated by the European Consortium for Ocean Research Drilling (ECORD). Each MSP expedition is unique within the Integrated Ocean Drilling Program (IODP). In order to complement the abilities of the JOIDES Resolution and the Chikyu, the ECORD Science Operator (ESO) must source vessels and technology suitable for each MSP proposal on a case-by-case basis. The result is that ESO can meet scientific requirements in a flexible manner, whilst maintaining the measurements required for the IODP legacy programme. The process of tendering within EU journals for vessels and technology means that the planning process for each MSP Expedition starts many years in advance of the operational phase. Involvement of proposal proponents from this early stage often leads to the recognition for technological research and development to best meet the scientific aims and objectives. One example of this is the planning for the Atlantis Massif proposal, with collaborative development between the British Geological Survey (BGS) and MARUM, University of Bremen, on suitable instruments for seabed drills, with the European Petrophysics Consortium (EPC) driving the development of suitable wireline logging tools that can be used in association with such seabed systems. Other technological developments being undertaken within the European IODP community include in-situ pressure sampling for gas hydrate expeditions, deep biosphere and fluid sampling equipment and CORK technology. This multi-national collaborative approach is also employed by ESO in the operational phase. IODP Expedition 302 ACEX saw vessel and ice management support from Russia and Sweden to facilitate the first drilling undertaken in Arctic sea ice. A review of MSP expeditions past, present and future reveal the significant impact of European led operations and scientific research within the current IODP programme, and also looking forward to the start of the new International

  17. The Doktabörse – an innovative online platform for research projects at the medical faculty of the LMU Munich

    Directory of Open Access Journals (Sweden)

    Nicolai, Leo

    2017-08-01

    Full Text Available Introduction: One of the most important extracurricular aspects of medical studies in Germany is a research thesis completed by most students. This research project often times conveys relevant competencies for the physician’s role as scientist. Nevertheless, the choice of the right project remains a challenge. Reasons for this are among others, missing structures for a comprehensive overview of research groups and their respective projects.Description of the project: We developed the online platform as an online marketplace for doctoral research projects. The platform enables authorized researchers to create working groups and upload, deactivate and change research projects within their institute. For interested students, a front end with integrated search function displays these projects in a structured and well-arranged way. In parallel, the provides for a comprehensive overview of research at the medical faculty. We evaluated Researchers‘ and students‘ use of the platform. Results: 96,6% of students participating in the evaluation (n=400 were in favor of a centralized research platform at the medical faculty. The platform grew at a steady pace and included 120 research groups in June 2016. The students appreciated the structure and design of the Two thirds of all uploaded projects matched successfully with doctoral students via the platform and over 94% of researchers stated that they did not need technical assistance with uploading projects and handling the platform. Discussion: The represents an innovative and well accepted platform for doctoral research projects. The platform is perceived positively by researchers and students alike. However, students criticized limited extent and timeliness of offered projects.In addition, the platform serves as databank of research at the medical faculty of the LMU Munich. The future potential of this platform is to provide for an integrated management solution of doctoral thesis projects

  18. Use of Web 2.0 Social Media Platforms to Promote Community-Engaged Research Dialogs: A Preliminary Program Evaluation

    Science.gov (United States)

    Valdez Soto, Miguel; Bishop, Shawn G; Aase, Lee A; Timimi, Farris K; Montori, Victor M; Patten, Christi A

    2016-01-01

    Background Community-engaged research is defined by the Institute of Medicine as the process of working collaboratively with groups of people affiliated by geographic proximity, special interests, or similar situations with respect to issues affecting their well-being. Traditional face-to-face community-engaged research is limited by geographic location, limited in resources, and/or uses one-way communications. Web 2.0 technologies including social media are novel communication channels for community-engaged research because these tools can reach a broader audience while promoting bidirectional dialogs. Objective This paper reports on a preliminary program evaluation of the use of social media platforms for promoting engagement of researchers and community representatives in dialogs about community-engaged research. Methods For this pilot program evaluation, the Clinical and Translational Science Office for Community Engagement in Research partnered with the Social Media Network at our institution to create a WordPress blog and Twitter account. Both social media platforms were facilitated by a social media manager. We used descriptive analytics for measuring engagement with WordPress and Twitter over an 18-month implementation period during 2014-2016. For the blog, we examined type of user (researcher, community representative, other) and used content analysis to generate the major themes from blog postings. For use of Twitter, we examined selected demographics and impressions among followers. Results There were 76 blog postings observed from researchers (48/76, 64%), community representatives (23/76, 32%) and funders (5/76, 8%). The predominant themes of the blog content were research awareness and dissemination of community-engaged research (35/76, 46%) and best practices (23/76, 30%). For Twitter, we obtained 411 followers at the end of the 18-month evaluation period, with an increase of 42% (from 280 to 411) over the final 6 months. Followers reported varied

  19. Use of Web 2.0 Social Media Platforms to Promote Community-Engaged Research Dialogs: A Preliminary Program Evaluation.

    Science.gov (United States)

    Valdez Soto, Miguel; Balls-Berry, Joyce E; Bishop, Shawn G; Aase, Lee A; Timimi, Farris K; Montori, Victor M; Patten, Christi A

    2016-09-09

    Community-engaged research is defined by the Institute of Medicine as the process of working collaboratively with groups of people affiliated by geographic proximity, special interests, or similar situations with respect to issues affecting their well-being. Traditional face-to-face community-engaged research is limited by geographic location, limited in resources, and/or uses one-way communications. Web 2.0 technologies including social media are novel communication channels for community-engaged research because these tools can reach a broader audience while promoting bidirectional dialogs. This paper reports on a preliminary program evaluation of the use of social media platforms for promoting engagement of researchers and community representatives in dialogs about community-engaged research. For this pilot program evaluation, the Clinical and Translational Science Office for Community Engagement in Research partnered with the Social Media Network at our institution to create a WordPress blog and Twitter account. Both social media platforms were facilitated by a social media manager. We used descriptive analytics for measuring engagement with WordPress and Twitter over an 18-month implementation period during 2014-2016. For the blog, we examined type of user (researcher, community representative, other) and used content analysis to generate the major themes from blog postings. For use of Twitter, we examined selected demographics and impressions among followers. There were 76 blog postings observed from researchers (48/76, 64%), community representatives (23/76, 32%) and funders (5/76, 8%). The predominant themes of the blog content were research awareness and dissemination of community-engaged research (35/76, 46%) and best practices (23/76, 30%). For Twitter, we obtained 411 followers at the end of the 18-month evaluation period, with an increase of 42% (from 280 to 411) over the final 6 months. Followers reported varied geographic location (321/411, 78

  20. Using online, crowdsourcing platforms for data collection in personality disorder research: The example of Amazon's Mechanical Turk.

    Science.gov (United States)

    Miller, Joshua D; Crowe, Michael; Weiss, Brandon; Maples-Keller, Jessica L; Lynam, Donald R

    2017-01-01

    The use of crowdsourcing platforms such as Amazon's Mechanical Turk (MTurk) for data collection in the behavioral sciences has increased substantially in the past several years due in large part to (a) the ability to recruit large samples, (b) the inexpensiveness of data collection, (c) the speed of data collection, and (d) evidence that the data collected are, for the most part, of equal or better quality to that collected in undergraduate research pools. In this review, we first evaluate the strengths and potential limitations of this approach to data collection. Second, we examine how MTurk has been used to date in personality disorder (PD) research and compare the characteristics of such research to PD research conducted in other settings. Third, we compare PD trait data from the Section III trait model of the DSM-5 collected via MTurk to data collected using undergraduate and clinical samples with regard to internal consistency, mean-level differences, and factor structure. Overall, we conclude that platforms such as MTurk have much to offer PD researchers, especially for certain kinds of research (e.g., where large samples are required and there is a need for iterative sampling). Whether MTurk itself remains the predominant model of such platforms is unclear, however, and will largely depend on decisions related to cost effectiveness and the development of alternatives that offer even greater flexibility. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  1. Ocean Data Interoperability Platform (ODIP): using regional data systems for global ocean research

    Science.gov (United States)

    Schaap, D.; Thijsse, P.; Glaves, H.

    2017-12-01

    Ocean acidification, loss of coral reefs, sustainable exploitation of the marine environment are just a few of the challenges researchers around the world are currently attempting to understand and address. However, studies of these ecosystem level challenges are impossible unless researchers can discover and re-use the large volumes of interoperable multidisciplinary data that are currently only accessible through regional and global data systems that serve discreet, and often discipline specific, user communities. The plethora of marine data systems currently in existence are also using different standards, technologies and best practices making re-use of the data problematic for those engaged in interdisciplinary marine research. The Ocean Data Interoperability Platform (ODIP) is responding to this growing demand for discoverable, accessible and reusable data by establishing the foundations for a common global framework for marine data management. But creation of such an infrastructure is a major undertaking, and one that needs to be achieved in part by establishing different levels of interoperability across existing regional and global marine e-infrastructures. Workshops organised by ODIP II facilitate dialogue between selected regional and global marine data systems in an effort to identify potential solutions that integrate these marine e-infrastructures. The outcomes of these discussions have formed the basis for a number of prototype development tasks that aim to demonstrate effective sharing of data across multiple data systems, and allow users to access data from more than one system through a single access point. The ODIP II project is currently developing four prototype solutions that are establishing interoperability between selected regional marine data management infrastructures in Europe, the USA, Canada and Australia, and with the global POGO, IODE Ocean Data Portal (ODP) and GEOSS systems. The potential impact of implementing these solutions for

  2. The smartphone as a platform for wearable cameras in health research.

    Science.gov (United States)

    Gurrin, Cathal; Qiu, Zhengwei; Hughes, Mark; Caprani, Niamh; Doherty, Aiden R; Hodges, Steve E; Smeaton, Alan F

    2013-03-01

    The Microsoft SenseCam, a small camera that is worn on the chest via a lanyard, increasingly is being deployed in health research. However, the SenseCam and other wearable cameras are not yet in widespread use because of a variety of factors. It is proposed that the ubiquitous smartphones can provide a more accessible alternative to SenseCam and similar devices. To perform an initial evaluation of the potential of smartphones to become an alternative to a wearable camera such as the SenseCam. In 2012, adults were supplied with a smartphone, which they wore on a lanyard, that ran life-logging software. Participants wore the smartphone for up to 1 day and the resulting life-log data were both manually annotated and automatically analyzed for the presence of visual concepts. The results were compared to prior work using the SenseCam. In total, 166,000 smartphone photos were gathered from 47 individuals, along with associated sensor readings. The average time spent wearing the device across all users was 5 hours 39 minutes (SD=4 hours 11 minutes). A subset of 36,698 photos was selected for manual annotation by five researchers. Software analysis of these photos supports the automatic identification of activities to a similar level of accuracy as for SenseCam images in a previous study. Many aspects of the functionality of a SenseCam largely can be replicated, and in some cases enhanced, by the ubiquitous smartphone platform. This makes smartphones good candidates for a new generation of wearable sensing devices in health research, because of their widespread use across many populations. It is envisioned that smartphones will provide a compelling alternative to the dedicated SenseCam hardware for a number of users and application areas. This will be achieved by integrating new types of sensor data, leveraging the smartphone's real-time connectivity and rich user interface, and providing support for a range of relatively sophisticated applications. Copyright © 2013

  3. Platform for systems medicine research and diagnostic applications in psychotic disorders-The METSY project.

    Science.gov (United States)

    Frank, Elisabeth; Maier, Dieter; Pajula, Juha; Suvitaival, Tommi; Borgan, Faith; Butz-Ostendorf, Markus; Fischer, Alexander; Hietala, Jarmo; Howes, Oliver; Hyötyläinen, Tuulia; Janssen, Joost; Laurikainen, Heikki; Moreno, Carmen; Suvisaari, Jaana; Van Gils, Mark; Orešič, Matej

    2018-04-01

    Psychotic disorders are associated with metabolic abnormalities including alterations in glucose and lipid metabolism. A major challenge in the treatment of psychosis is to identify patients with vulnerable metabolic profiles who may be at risk of developing cardiometabolic co-morbidities. It is established that both central and peripheral metabolic organs use lipids to control energy balance and regulate peripheral insulin sensitivity. The endocannabinoid system, implicated in the regulation of glucose and lipid metabolism, has been shown to be dysregulated in psychosis. It is currently unclear how these endocannabinoid abnormalities relate to metabolic changes in psychosis. Here we review recent research in the field of metabolic co-morbidities in psychotic disorders as well as the methods to study them and potential links to the endocannabinoid system. We also describe the bioinformatics platforms developed in the EU project METSY for the investigations of the biological etiology in patients at risk of psychosis and in first episode psychosis patients. The METSY project was established with the aim to identify and evaluate multi-modal peripheral and neuroimaging markers that may be able to predict the onset and prognosis of psychiatric and metabolic symptoms in patients at risk of developing psychosis and first episode psychosis patients. Given the intrinsic complexity and widespread role of lipid metabolism, a systems biology approach which combines molecular, structural and functional neuroimaging methods with detailed metabolic characterisation and multi-variate network analysis is essential in order to identify how lipid dysregulation may contribute to psychotic disorders. A decision support system, integrating clinical, neuropsychological and neuroimaging data, was also developed in order to aid clinical decision making in psychosis. Knowledge of common and specific mechanisms may aid the etiopathogenic understanding of psychotic and metabolic disorders

  4. Systematic calibration of an integrated x-ray and optical tomography system for preclinical radiation research

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Yidong, E-mail: yidongyang@med.miami.edu [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231 and Department of Radiation Oncology, University of Miami School of Medicine, Miami, Florida 33136 (United States); Wang, Ken Kang-Hsin; Wong, John W. [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231 (United States); Eslami, Sohrab; Iordachita, Iulian I. [Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, Maryland 21218 (United States); Patterson, Michael S. [Juravinski Cancer Centre and Department of Medical Physics and Applied Radiation Sciences, McMaster University, Hamilton, Ontario L8S4K1 (Canada)

    2015-04-15

    Purpose: The cone beam computed tomography (CBCT) guided small animal radiation research platform (SARRP) has been developed for focal tumor irradiation, allowing laboratory researchers to test basic biological hypotheses that can modify radiotherapy outcomes in ways that were not feasible previously. CBCT provides excellent bone to soft tissue contrast, but is incapable of differentiating tumors from surrounding soft tissue. Bioluminescence tomography (BLT), in contrast, allows direct visualization of even subpalpable tumors and quantitative evaluation of tumor response. Integration of BLT with CBCT offers complementary image information, with CBCT delineating anatomic structures and BLT differentiating luminescent tumors. This study is to develop a systematic method to calibrate an integrated CBCT and BLT imaging system which can be adopted onboard the SARRP to guide focal tumor irradiation. Methods: The integrated imaging system consists of CBCT, diffuse optical tomography (DOT), and BLT. The anatomy acquired from CBCT and optical properties acquired from DOT serve as a priori information for the subsequent BLT reconstruction. Phantoms were designed and procedures were developed to calibrate the CBCT, DOT/BLT, and the entire integrated system. Geometrical calibration was performed to calibrate the CBCT system. Flat field correction was performed to correct the nonuniform response of the optical imaging system. Absolute emittance calibration was performed to convert the camera readout to the emittance at the phantom or animal surface, which enabled the direct reconstruction of the bioluminescence source strength. Phantom and mouse imaging were performed to validate the calibration. Results: All calibration procedures were successfully performed. Both CBCT of a thin wire and a euthanized mouse revealed no spatial artifact, validating the accuracy of the CBCT calibration. The absolute emittance calibration was validated with a 650 nm laser source, resulting in a 3

  5. Systematic calibration of an integrated x-ray and optical tomography system for preclinical radiation research

    International Nuclear Information System (INIS)

    Yang, Yidong; Wang, Ken Kang-Hsin; Wong, John W.; Eslami, Sohrab; Iordachita, Iulian I.; Patterson, Michael S.

    2015-01-01

    Purpose: The cone beam computed tomography (CBCT) guided small animal radiation research platform (SARRP) has been developed for focal tumor irradiation, allowing laboratory researchers to test basic biological hypotheses that can modify radiotherapy outcomes in ways that were not feasible previously. CBCT provides excellent bone to soft tissue contrast, but is incapable of differentiating tumors from surrounding soft tissue. Bioluminescence tomography (BLT), in contrast, allows direct visualization of even subpalpable tumors and quantitative evaluation of tumor response. Integration of BLT with CBCT offers complementary image information, with CBCT delineating anatomic structures and BLT differentiating luminescent tumors. This study is to develop a systematic method to calibrate an integrated CBCT and BLT imaging system which can be adopted onboard the SARRP to guide focal tumor irradiation. Methods: The integrated imaging system consists of CBCT, diffuse optical tomography (DOT), and BLT. The anatomy acquired from CBCT and optical properties acquired from DOT serve as a priori information for the subsequent BLT reconstruction. Phantoms were designed and procedures were developed to calibrate the CBCT, DOT/BLT, and the entire integrated system. Geometrical calibration was performed to calibrate the CBCT system. Flat field correction was performed to correct the nonuniform response of the optical imaging system. Absolute emittance calibration was performed to convert the camera readout to the emittance at the phantom or animal surface, which enabled the direct reconstruction of the bioluminescence source strength. Phantom and mouse imaging were performed to validate the calibration. Results: All calibration procedures were successfully performed. Both CBCT of a thin wire and a euthanized mouse revealed no spatial artifact, validating the accuracy of the CBCT calibration. The absolute emittance calibration was validated with a 650 nm laser source, resulting in a 3

  6. Research progress of anti-icing/deicing technologies for polar ships and offshore platforms

    Directory of Open Access Journals (Sweden)

    XIE Qiang

    2017-01-01

    Full Text Available The polar regions present adverse circumstances of high humidity and strong air-sea exchange. As such, the surfaces of ships and platforms (oil exploiting and drilling platforms serving in polar regions can easily be frozen by ice accretion, which not only affects the operation of the equipment but also threatens safety. This paper summarizes the status of the anti-icing/deicing technologies of both China and abroad for polar ships and offshore platforms, and introduces the various effects of ice accretion on polar ships and offshore platforms, and the resulting safety impacts. It then reviews existing anti-icing/deicing technologies and methods of both China and abroad, including such active deicing methods as electric heating, infrared heating and ultrasonic guided wave deicing, as well as such passive deicing methods as super hydrophobic coating, sacrificial coating, aqueous lubricating layer coating and low cross-link density (with interfacial slippage coating, summarizes their applicability to polar ships and offshore platforms, and finally discusses their advantages/disadvantages.

  7. The research of a gyro-stabilized platform and POS application technology in airborne remote sensing

    Science.gov (United States)

    Xu, Jiang; Du, Qi

    2009-07-01

    The distortion of the collected images usually takes place since the attitude changes along with the flying aerocraft on airborne remote sensing. In order to get original images without distortion, it is necessary to use professional gyro-stabilized platform. In addition to this, another solution of correcting the original image distortion is to utilize later geometric rectification using position & orientation system ( POS ) data. The third way is to utilize medium-accuracy stabilized platform to control the distortion at a tolerant range, and then make use of the data obtained by high-solution posture measure system to correct the low-quality remote sensing images. The third way which takes advantage of both techniques is better than using only one of the two other ways. This paper introduces several kinds of structural forms of gyro-stabilized platforms, and POS acquiring instruments respectively. Then, the essay will make some analysis of their advantages and disadvantages, key technologies and the application experiment of the third method. After the analysis, the thesis discusses the design of the gyro-stabilized platform. The thesis provides crucial information not only for the application technology of gyro-stabilized platform and POS but also for future development.

  8. The QuakeFinder Magnetometer Network - a Platform for Earth and Space Science Research

    Science.gov (United States)

    Bleier, T.; Kappler, K. N.; Schneider, D.

    2016-12-01

    QuakeFinder (QF) is a humanitarian research and development project attempting to characterize earth-emitting electromagnetic (EM) signals as potential precursors to earthquakes. Beginning in 2005, QF designed, built, deployed and now maintains an array of 165 remote monitoring stations in 6 countries (US/California, Taiwan, Greece, Indonesia, Peru and Chile). Having amassed approximately 70 TB of data and greater than 140 earthquakes (M4+), QF is focused on the data analysis and signal processing algorithms in our effort to enable a forecasting capability. QF's autonomous stations, located along major fault lines, collect and transmit electromagnetic readings from 3-axis induction magnetometers and positive/negative ion sensors, a geophone, as well as various station health status and local conditions. The induction magnetometers, oriented N-S,E-W and vertically, have a 40 nT range and 1 pT sensitivity. Data is continuously collected at 50 samples/sec (sps), GPS time-stamped and transmitted, primarily through cell phone networks, to our data center in Palo Alto, California. The induction magnetometers routinely detect subtle geomagnetic and ionospheric disturbances as observed worldwide. QF seeks to make available both historic data and the array platform to strategic partners in the EM-related research and operation fields. The QF system will be described in detail with examples of local and regional geomagnetic activity. The stations are robust and will be undergoing a system-level upgrade in the near future. Domestically, QF maintains a 98% `up time' among the 120 stations in California while internationally our metric is typically near 80%. Irregular cell phone reception is chief among the reasons for outages although little data has been lost as the stations can store up to 90 days of data. These data are retrieved by QF personnel or, when communication is reestablished, the QF data ingest process automatically updates the database. Planned station upgrades

  9. TOPAS: An innovative proton Monte Carlo platform for research and clinical applications

    Energy Technology Data Exchange (ETDEWEB)

    Perl, J.; Shin, J.; Schuemann, J.; Faddegon, B.; Paganetti, H. [SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025 (United States); University of California San Francisco Comprehensive Cancer Center, 1600 Divisadero Street, San Francisco, California 94143-1708 (United States); Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114 (United States); University of California San Francisco Comprehensive Cancer Center, 1600 Divisadero Street, San Francisco, California 94143-1708 (United States); Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114 (United States)

    2012-11-15

    Purpose: While Monte Carlo particle transport has proven useful in many areas (treatment head design, dose calculation, shielding design, and imaging studies) and has been particularly important for proton therapy (due to the conformal dose distributions and a finite beam range in the patient), the available general purpose Monte Carlo codes in proton therapy have been overly complex for most clinical medical physicists. The learning process has large costs not only in time but also in reliability. To address this issue, we developed an innovative proton Monte Carlo platform and tested the tool in a variety of proton therapy applications. Methods: Our approach was to take one of the already-established general purpose Monte Carlo codes and wrap and extend it to create a specialized user-friendly tool for proton therapy. The resulting tool, TOol for PArticle Simulation (TOPAS), should make Monte Carlo simulation more readily available for research and clinical physicists. TOPAS can model a passive scattering or scanning beam treatment head, model a patient geometry based on computed tomography (CT) images, score dose, fluence, etc., save and restart a phase space, provides advanced graphics, and is fully four-dimensional (4D) to handle variations in beam delivery and patient geometry during treatment. A custom-designed TOPAS parameter control system was placed at the heart of the code to meet requirements for ease of use, reliability, and repeatability without sacrificing flexibility. Results: We built and tested the TOPAS code. We have shown that the TOPAS parameter system provides easy yet flexible control over all key simulation areas such as geometry setup, particle source setup, scoring setup, etc. Through design consistency, we have insured that user experience gained in configuring one component, scorer or filter applies equally well to configuring any other component, scorer or filter. We have incorporated key lessons from safety management, proactively

  10. TOPAS: An innovative proton Monte Carlo platform for research and clinical applications

    International Nuclear Information System (INIS)

    Perl, J.; Shin, J.; Schümann, J.; Faddegon, B.; Paganetti, H.

    2012-01-01

    Purpose: While Monte Carlo particle transport has proven useful in many areas (treatment head design, dose calculation, shielding design, and imaging studies) and has been particularly important for proton therapy (due to the conformal dose distributions and a finite beam range in the patient), the available general purpose Monte Carlo codes in proton therapy have been overly complex for most clinical medical physicists. The learning process has large costs not only in time but also in reliability. To address this issue, we developed an innovative proton Monte Carlo platform and tested the tool in a variety of proton therapy applications. Methods: Our approach was to take one of the already-established general purpose Monte Carlo codes and wrap and extend it to create a specialized user-friendly tool for proton therapy. The resulting tool, TOol for PArticle Simulation (TOPAS), should make Monte Carlo simulation more readily available for research and clinical physicists. TOPAS can model a passive scattering or scanning beam treatment head, model a patient geometry based on computed tomography (CT) images, score dose, fluence, etc., save and restart a phase space, provides advanced graphics, and is fully four-dimensional (4D) to handle variations in beam delivery and patient geometry during treatment. A custom-designed TOPAS parameter control system was placed at the heart of the code to meet requirements for ease of use, reliability, and repeatability without sacrificing flexibility. Results: We built and tested the TOPAS code. We have shown that the TOPAS parameter system provides easy yet flexible control over all key simulation areas such as geometry setup, particle source setup, scoring setup, etc. Through design consistency, we have insured that user experience gained in configuring one component, scorer or filter applies equally well to configuring any other component, scorer or filter. We have incorporated key lessons from safety management, proactively

  11. The use of Saildrones as Long Endurance, Ocean Research Platforms in Remote and Extreme Environments.

    Science.gov (United States)

    Jenkins, R.; Peacock, D.; Jones, E.

    2016-02-01

    The world's oceans are experiencing significant change, which will have a profound impact on ecosystems, fish stocks and climate. Furthermore, the areas where some of the biggest changes are occurring are also some of the least measured and understood. This is largely due to their remote location and/or harsh environment, where the cost of deploying sensors is significant. New technologies are required to supplement ships and mooring data to meet the demand for longer, more economical deployments with the ability for real-time data and adaptive sampling. The Saildrone was designed to meet this need, providing the ability to reach almost any part of the world's oceans, without requiring a ship. Deployed from the dock, the unmanned Saildrone navigates autonomously to the area of interest, where it operates for extended periods before returning to shore for servicing and subsequent re-deployment. The Saildrone is propelled by wind power from a 4 m solid wing. Stability is provided by static weight in the keel and outrigger hulls. The 5.8 m hull includes several payload bays, with a payload capacity of 100 kg. Working with the Pacific Marine Environmental Laboratory (PMEL), under a collaborative Research and Development Agreement (CRADA), the Saildrone platform was equipped with a suite of meteorological and oceanographic sensors that would enable a wide variety of ocean research missions to be undertaken. After field tests in San Francisco Bay, a 3 month mission was conducted in the eastern Bering Sea in spring 2015. The mission included rough sea-trials, sensor comparisons in coordination with the NOAAS Oscar Dyson, and a survey of the northern Bering Sea shortly after ice retreat. The mission was completed as planned, with the two Saildrones (SD-126 & SD-128) returning to the dock from which they were deployed after 97 days and each completing 4400 nautical miles. During the second half of 2015, two subsequent missions were conducted in the Gulf of Mexico. Two

  12. Research on acceleration method of reactor physics based on FPGA platforms

    International Nuclear Information System (INIS)

    Li, C.; Yu, G.; Wang, K.

    2013-01-01

    The physical designs of the new concept reactors which have complex structure, various materials and neutronic energy spectrum, have greatly improved the requirements to the calculation methods and the corresponding computing hardware. Along with the widely used parallel algorithm, heterogeneous platforms architecture has been introduced into numerical computations in reactor physics. Because of the natural parallel characteristics, the CPU-FPGA architecture is often used to accelerate numerical computation. This paper studies the application and features of this kind of heterogeneous platforms used in numerical calculation of reactor physics through practical examples. After the designed neutron diffusion module based on CPU-FPGA architecture achieves a 11.2 speed up factor, it is proved to be feasible to apply this kind of heterogeneous platform into reactor physics. (authors)

  13. Launching a virtual decision lab: development and field-testing of a web-based patient decision support research platform.

    Science.gov (United States)

    Hoffman, Aubri S; Llewellyn-Thomas, Hilary A; Tosteson, Anna N A; O'Connor, Annette M; Volk, Robert J; Tomek, Ivan M; Andrews, Steven B; Bartels, Stephen J

    2014-12-12

    Over 100 trials show that patient decision aids effectively improve patients' information comprehension and values-based decision making. However, gaps remain in our understanding of several fundamental and applied questions, particularly related to the design of interactive, personalized decision aids. This paper describes an interdisciplinary development process for, and early field testing of, a web-based patient decision support research platform, or virtual decision lab, to address these questions. An interdisciplinary stakeholder panel designed the web-based research platform with three components: a) an introduction to shared decision making, b) a web-based patient decision aid, and c) interactive data collection items. Iterative focus groups provided feedback on paper drafts and online prototypes. A field test assessed a) feasibility for using the research platform, in terms of recruitment, usage, and acceptability; and b) feasibility of using the web-based decision aid component, compared to performance of a videobooklet decision aid in clinical care. This interdisciplinary, theory-based, patient-centered design approach produced a prototype for field-testing in six months. Participants (n = 126) reported that: the decision aid component was easy to use (98%), information was clear (90%), the length was appropriate (100%), it was appropriately detailed (90%), and it held their interest (97%). They spent a mean of 36 minutes using the decision aid and 100% preferred using their home/library computer. Participants scored a mean of 75% correct on the Decision Quality, Knowledge Subscale, and 74 out of 100 on the Preparation for Decision Making Scale. Completing the web-based decision aid reduced mean Decisional Conflict scores from 31.1 to 19.5 (p development of a web-based patient decision support research platform that was feasible for use in research studies in terms of recruitment, acceptability, and usage. Within this platform, the web

  14. Research on website construction based on website group platform of Chengdu sport institution

    Science.gov (United States)

    Hu, Zunyu

    2018-04-01

    This paper describes the necessity of website construction based on the website group of Chengdu sport institute, and discusses the technical features of the website group, Based on the website group platform architecture, the key technologies such as Web Service, AJAX, RSS and other key technologies are used to realize the construction of the website. Based on the website group platform architecture of the site, it effectively solves the information isolated island between the sites, and realizes the information sharing and resource integration. It is also more convenient that site and other sites have composed of site group integrated operation and maintenance.

  15. The ASSISTments Ecosystem: Building a Platform That Brings Scientists and Teachers Together for Minimally Invasive Research on Human Learning and Teaching

    Science.gov (United States)

    Heffernan, Neil T.; Heffernan, Cristina Lindquist

    2014-01-01

    The ASSISTments project is an ecosystem of a few hundred teachers, a platform, and researchers working together. Development professionals help train teachers and get teachers to participate in studies. The platform and these teachers help researchers (sometimes explicitly and sometimes implicitly) simply by using content the teacher selects. The…

  16. Research on Hydrodynamic Interference Suppression of Bottom-Mounted Monitoring Platform with Fairing Structure

    Science.gov (United States)

    Wang, Zhen; Zheng, Yi; Mao, Yu-feng; Wang, Ya-zhou; Yu, Yan-ting; Liu, Hong-ning

    2018-03-01

    In the disturbance of unsteady flow field under the sea, the monitoring accuracy and precision of the bottom-mounted acoustic monitoring platform will decrease. In order to reduce the hydrodynamic interference, the platform wrapped with fairing structure and separated from the retrieval unit is described. The suppression effect evaluation based on the correlation theory of sound pressure and particle velocity for spherical wave in infinite homogeneous medium is proposed and the difference value between them is used to evaluate the hydrodynamic restraining performance of the bottom-mounted platform under far field condition. Through the sea test, it is indicated that the platform with sparse layers fairing structure (there are two layers for the fairing, in which the inside layer is 6-layers sparse metal net, and the outside layer is 1-layer polyester cloth, and then it takes sparse layers for short) has no attenuation in the sound pressure response to the sound source signal, but obvious suppression in the velocity response to the hydrodynamic noise. The effective frequency of the fairing structure is decreased below 10 Hz, and the noise magnitude is reduced by 10 dB. With the comparison of different fairing structures, it is concluded that the tighter fairing structure can enhance the performance of sound transmission and flow restraining.

  17. EPCAL: ETS Platform for Collaborative Assessment and Learning. Research Report. ETS RR-17-49

    Science.gov (United States)

    Hao, Jiangang; Liu, Lei; von Davier, Alina A.; Lederer, Nathan; Zapata-Rivera, Diego; Jaki, Peter; Bakkenson, Michael

    2017-01-01

    Most existing software tools for online collaboration are designed to support the collaboration itself instead of the study of collaboration with a systematic team and task management system. In this report, we identify six important features for a platform to facilitate the study of online collaboration. We then introduce the Educational Testing…

  18. A strategic research agenda for photovoltaic solar energy technology : report of the EU PV technology platform

    NARCIS (Netherlands)

    Sinke, W.C.; Zolingen, van R.J.C.; Ballif, C.; Bett, A.; Dimmler, B.; Dimova-Malinovska, D.; Fath, P.; Ferrazza, F.; Gabler, H.-J.; Hall, M.; Marti, A.; Mason, N.; Mellikov, E.; Milner, A.; Mogensen, P.; Panhuber, C.; Pearsall, N.; Poortmans, J.; Protogeropoulos, C.; Sarre, G.; Sarti, D.; Strauss, P.; Topic, M.; Zdanowicz, T.

    2007-01-01

    The EU PV Technology Platform [1] aims at joining forces on a European level to contribute to the further development of photovoltaic solar energy into a competitive technology that can be applied on a large scale and to the strengthening of the position of the European PV industry on the global

  19. Quality of SME Business Transfers Matching Platforms: Research Outcomes of 12 European Countries

    NARCIS (Netherlands)

    Oriol Alba; Edwin Weesie; Marie Depelssemaker; Lex van Teeffelen; Nicolas Pirotte

    2016-01-01

    From the preface : The European Commission supports Member States by providing them with recommendations, guidelines, information and good practices. For years, the European Commission has stimulated Member States to develop matching platforms to efficiently support sellers and buyers of SMEs in

  20. {cross-disciplinary} Data CyberInfrastructure: A Different Approach to Developing Collaborative Earth and Environmental Science Research Platforms

    Science.gov (United States)

    Lenhardt, W. C.; Krishnamurthy, A.; Blanton, B.; Conway, M.; Coposky, J.; Castillo, C.; Idaszak, R.

    2017-12-01

    An integrated science cyberinfrastructure platform is fast becoming a norm in science, particularly where access to distributed resources, access to compute, data management tools, and collaboration tools are accessible to the end-user scientist without the need to spin up these services on their own. There platforms have various types of labels ranging from data commons to science-as-a-service. They tend to share common features, as outlined above. What tends to distinguish these platforms, however, is their affinity for particular domains, NanoHub - nanomaterials, iPlant - plant biology, Hydroshare - hydrology, and so on. The challenge still remains how to enable these platforms to be more easily adopted for use by other domains. This paper will provide an overview of RENCI's approach to creating a science platform that can be more easily adopted by new communities while also endeavoring to accelerate their research. At RENCI, we started with Hydroshare, but have now worked to generalize the methodology for application to other domains. This new effort is called xDCi, or {cross-disciplinary} Data CyberInfrastructure. We have adopted a broader approach to the challenge of domain adoption and includes two key elements in addition to the technology component. The first of these is how development is operationalized. RENCI implements a DevOps model of continuous development and deployment. This greatly increases the speed by which a new platform can come online and be refined to meet domain needs. DevOps also allows for migration over time, i.e. sustainability. The second element is a concierge model. In addition to the technical elements, and the more responsive development process, RENCI also supports domain adoption of the platform by providing a concierge service— dedicated expertise- in the following areas, Information Technology, Sustainable Software, Data Science, and Sustainability. The success of the RENCI methodology is illustrated by the adoption of the

  1. A systematic review of social networking sites: innovative platforms for health research targeting adolescents and young adults.

    Science.gov (United States)

    Park, Bu Kyung; Calamaro, Christina

    2013-09-01

    To review the evidence to determine if social networking sites (SNS) are effective tools for health research in the adolescent and young adult populations. Systematic review of published research articles focused on use of SNS for youth health research. Seventeen articles were selected that met the following criteria: used SNS at any stage of study, participants between 13 and 25 years of age, English language, and both international and national studies. Reviewers categorized selected studies based on the way SNS were used. Utilization of SNS for effectively implementing research with adolescents and young adults include (a) recruitment, (b) intervention, and (c) measurement. Four findings about advantages of using SNS apparent in this review are (a) ease of access to youth, (b) cost effectiveness in recruitment, (c) ease of intervention, and (d) reliable screening venue of mental status and high-risk behaviors. Although this literature review showed relatively minimal research to date on the use of SNS for research targeting adolescents and young adults, the impact of using SNS for health research is of considerable importance for researchers as well as participants. With careful focus, SNS can become a valuable platform to access, recruit, and deliver health interventions in a cost-effective manner to youth populations as well as hard-to-reach minority or underserved populations. The evidence demonstrates the usefulness of SNS as innovative platforms for health promotion among adolescents and young adults. © 2013 Sigma Theta Tau International.

  2. A survey of informatics platforms that enable distributed comparative effectiveness research using multi-institutional heterogeneous clinical data

    Science.gov (United States)

    Sittig, Dean F.; Hazlehurst, Brian L.; Brown, Jeffrey; Murphy, Shawn; Rosenman, Marc; Tarczy-Hornoch, Peter; Wilcox, Adam B.

    2012-01-01

    Comparative Effectiveness Research (CER) has the potential to transform the current healthcare delivery system by identifying the most effective medical and surgical treatments, diagnostic tests, disease prevention methods and ways to deliver care for specific clinical conditions. To be successful, such research requires the identification, capture, aggregation, integration, and analysis of disparate data sources held by different institutions with diverse representations of the relevant clinical events. In an effort to address these diverse demands, there have been multiple new designs and implementations of informatics platforms that provide access to electronic clinical data and the governance infrastructure required for inter-institutional CER. The goal of this manuscript is to help investigators understand why these informatics platforms are required and to compare and contrast six, large-scale, recently funded, CER-focused informatics platform development efforts. We utilized an 8-dimension, socio-technical model of health information technology use to help guide our work. We identified six generic steps that are necessary in any distributed, multi-institutional CER project: data identification, extraction, modeling, aggregation, analysis, and dissemination. We expect that over the next several years these projects will provide answers to many important, and heretofore unanswerable, clinical research questions. PMID:22692259

  3. A survey of informatics platforms that enable distributed comparative effectiveness research using multi-institutional heterogenous clinical data.

    Science.gov (United States)

    Sittig, Dean F; Hazlehurst, Brian L; Brown, Jeffrey; Murphy, Shawn; Rosenman, Marc; Tarczy-Hornoch, Peter; Wilcox, Adam B

    2012-07-01

    Comparative effectiveness research (CER) has the potential to transform the current health care delivery system by identifying the most effective medical and surgical treatments, diagnostic tests, disease prevention methods, and ways to deliver care for specific clinical conditions. To be successful, such research requires the identification, capture, aggregation, integration, and analysis of disparate data sources held by different institutions with diverse representations of the relevant clinical events. In an effort to address these diverse demands, there have been multiple new designs and implementations of informatics platforms that provide access to electronic clinical data and the governance infrastructure required for interinstitutional CER. The goal of this manuscript is to help investigators understand why these informatics platforms are required and to compare and contrast 6 large-scale, recently funded, CER-focused informatics platform development efforts. We utilized an 8-dimension, sociotechnical model of health information technology to help guide our work. We identified 6 generic steps that are necessary in any distributed, multi-institutional CER project: data identification, extraction, modeling, aggregation, analysis, and dissemination. We expect that over the next several years these projects will provide answers to many important, and heretofore unanswerable, clinical research questions.

  4. Standardized analysis and sharing of genome-phenome data for neuromuscular and rare disease research through the RD-Connect platform

    OpenAIRE

    Thompson, Rachel; Beltran, Sergi; Papakonstantinou, Anastasios; Cañada, Andrés; Fernández, Jose Maria; Thompson, Mark; Kaliyaperumal, Rajaram; Lair, Séverine; Sernadela, Pedro; Girdea, Marta; Brudno, Michael; Blavier, André; Lochmüller, Hanns; Roos, Andreas; Straub, Volker

    2016-01-01

    Abstract: RD-Connect (rd-connect.eu) is an EU-funded project building an integrated platform to narrow the gaps in rare disease research, where patient populations, clinical expertise and research communities are small in number and highly fragmented. Guided by the needs of rare disease researchers and with neuromuscular and neurodegenerative researchers as its original collaborators, the RD-Connect platform securely integrates multiple types of omics data (genomics, proteomics and transcript...

  5. Development of a Historical Hydrological online research and application platform for Switzerland - Historical Hydrological Atlas of Switzerland (HHAS)

    Science.gov (United States)

    Wetter, Oliver

    2017-04-01

    It is planned to develop and maintain a historical hydrological online platform for Switzerland, which shall be specially designed for the needs of research and federal, cantonal or private institutions being interested in hydrological risk assessment and protection measures. The aim is on the one hand to facilitate the access to raw data which generally is needed for further historical hydrological reconstruction and quantification, so that future research will be achieved in significantly shorter time. On the other hand, new historical hydrological research results shall be continuously included in order to establish this platform as a useful tool for the assessment of hydrological risk by including the long term experience of reconstructed pre-instrumental hydrological extreme events like floods and droughts. Meteorological parameters that may trigger extreme hydrological events, like monthly or seasonally resolved reconstructions of temperature and precipitation shall be made accessible in this platform as well. The ultimate goal will be to homogenise the reconstructed hydrological extreme events which usually appeared in the pre anthropogenic influence period under different climatological as well as different hydrological regimes and topographical conditions with the present day state. Long term changes of reconstructed small- to extreme flood seasonality, based on municipal accounting records, will be included in the platform as well. This helps - in combination with the before mentioned meteorological parameters - to provide an increased understanding of the major changes in the generally complex overall system that finally causes hydrological extreme events. The goal of my presentation at the Historical Climatology session is to give an overview about the applied historical climatological and historical hydrological methodologies that are applied on the historical raw data (evidence) to reconstruct pre instrumental hydrological events and meteorological

  6. Research on sudden environmental pollution public service platform construction based on WebGIS

    Science.gov (United States)

    Bi, T. P.; Gao, D. Y.; Zhong, X. Y.

    2016-08-01

    In order to actualize the social sharing and service of the emergency-response information for sudden pollution accidents, the public can share the risk source information service, dangerous goods control technology service and so on, The SQL Server and ArcSDE software are used to establish a spatial database to restore all kinds of information including risk sources, hazardous chemicals and handling methods in case of accidents. Combined with Chinese atmospheric environmental assessment standards, the SCREEN3 atmospheric dispersion model and one-dimensional liquid diffusion model are established to realize the query of related information and the display of the diffusion effect under B/S structure. Based on the WebGIS technology, C#.Net language is used to develop the sudden environmental pollution public service platform. As a result, the public service platform can make risk assessments and provide the best emergency processing services.

  7. A Research on the Model of Network Lending Platform in China

    OpenAIRE

    Li, Ying; Kobayashi, Mamoru

    2017-01-01

    In 1974, Professor Yunus has built microfinance institutions to alleviate poverty in Bangladesh, soon the microcredit model has gradually expanded around the world. In recent years, with the continuous innovation and development of the Internet and Mobile Internet, a variety of online platforms are growing rapidly and widely, As the economic and the continuous progresses on network technology have developed rapidly, Internet technology has quickly melt into the financial industry, Internet ne...

  8. Innovative and applied research on big data platforms of smart heritage

    Science.gov (United States)

    Qiu, J.; Li, J.; Sun, H.

    2015-08-01

    Big data has huge commercial value and potential. Under the background of big data, a heritage site is faced with a number of questions and challenges such as, how to accelerate industrial innovation, benign competition and the creation of new business value. Based on the analysis of service data from the national archaeological site and park, Yuan Ming Yuan, this paper investigates the common problems of site management operations such as, inappropriate cultural interpretation, insufficient consumer demand and so on. In order to solve these operational problems, a new service system called the "one platform - three systems" was put forward. This system includes the smart heritage platform and three management systems: the smart heritage management system, the 3-O (Online-Offline-Onsite) service system and the digital explanation system. Combined with the 3-O marketing operation, the platform can realize bidirectional interaction between heritage site management units and tourists, which can also benefit visitors to the heritage site by explaining the culture and history of the heritage site, bring about more demand for cultural information and expand the social and economic benefits.

  9. Construction of the Chinese Veteran Clinical Research (CVCR) platform for the assessment of non-communicable diseases.

    Science.gov (United States)

    Tan, Jiping; Li, Nan; Gao, Jing; Guo, Yuhe; Hu, Wei; Yang, Jinsheng; Yu, Baocheng; Yu, Jianmin; Du, Wei; Zhang, Wenjun; Cui, Lianqi; Wang, Qingsong; Xia, Xiangnan; Li, Jianjun; Zhou, Peiyi; Zhang, Baohe; Liu, Zhiying; Zhang, Shaogang; Sun, Lanying; Liu, Nan; Deng, Ruixiang; Dai, Wenguang; Yi, Fang; Chen, Wenjun; Zhang, Yongqing; Xue, Shenwu; Cui, Bo; Zhao, Yiming; Wang, Luning

    2014-01-01

    Based on the excellent medical care and management system for Chinese veterans, as well as the detailed medical documentation available, we aim to construct a Chinese Veteran Clinical Research (CVCR) platform on non-communicable diseases (NCDs) and carry out studies of the primary disabling NCDs. The Geriatric Neurology Department of Chinese People's Liberation Army General Hospital and veterans' hospitals serve as the leading and participating units in the platform construction. The fundamental constituents of the platform are veteran communities. Stratified typical cluster sampling is adopted to recruit veteran communities. A cross-sectional study of mental, neurological, and substance use (MNS) disorders are performed in two stages using screening scale such as the Mini-Mental State Examination and Montreal cognitive assessment, followed by systematic neuropsychological assessments to make clinical diagnoses, evaluated disease awareness and care situation. A total of 9 676 among 277 veteran communities from 18 cities are recruited into this platform, yielding a response rate of 83.86%. 8 812 subjects complete the MNS subproject screening and total response rate is 91.70%. The average participant age is (82.01±4.61) years, 69.47% of veterans are 80 years or older. Most participants are male (94.01%), 83.36% of subjects have at least a junior high school degree. The overall health status of veterans is good and stable. The most common NCD are cardiovascular disorders (86.44%), urinary and genital diseases (73.14%), eye and ear problems (66.25%), endocrine (56.56%) and neuro-psychiatric disturbances (50.78%). We first construct a veterans' comprehensive clinical research platform for the study of NCDs that is primarily composed of highly educated Chinese males of advanced age and utilize this platform to complete a cross-sectional national investigation of MNS disorders among veterans. The good and stable health condition of the veterans could facilitate the long

  10. Research on distributed heterogeneous data PCA algorithm based on cloud platform

    Science.gov (United States)

    Zhang, Jin; Huang, Gang

    2018-05-01

    Principal component analysis (PCA) of heterogeneous data sets can solve the problem that centralized data scalability is limited. In order to reduce the generation of intermediate data and error components of distributed heterogeneous data sets, a principal component analysis algorithm based on heterogeneous data sets under cloud platform is proposed. The algorithm performs eigenvalue processing by using Householder tridiagonalization and QR factorization to calculate the error component of the heterogeneous database associated with the public key to obtain the intermediate data set and the lost information. Experiments on distributed DBM heterogeneous datasets show that the model method has the feasibility and reliability in terms of execution time and accuracy.

  11. A RESEARCH ON SEAMLESS PLATFORM CHANGE OF REACTOR PROTECTION SYSTEM FROM PLC TO FPGA

    Directory of Open Access Journals (Sweden)

    JUNBEOM YOO

    2013-08-01

    Full Text Available The PLC (Programmable Logic Controller has been widely used to implement real-time controllers in nuclear RPSs (Reactor Protection Systems. Increasing complexity and maintenance cost, however, are now demanding more powerful and cost-effective implementation such as FPGA (Field-Programmable Gate Array. Abandoning all experience and knowledge accumulated over the decades and starting an all-new development approach is too risky for such safety-critical systems. This paper proposes an RPS software development process with a platform change from PLC to FPGA, while retaining all outputs from the established development. This paper transforms FBD designs of the PLC-based software development into a behaviorally-equivalent Verilog program, which is a starting point of a typical FPGA-based hardware development. We expect that the proposed software development process can bridge the gap between two software developing approaches with different platforms, such as PLC and FPGA. This paper also demonstrates its effectiveness using an example of a prototype version of a real-world RPS in Korea.

  12. A Research on Seamless Platform Change of Reactor Protection System From PLC to FPGA

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Junbeom; Lee, Jonghoon [Konkuk Univ., Seoul (Korea, Republic of); Lee, Jangsoo [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-08-15

    The PLC (Programmable Logic Controller) has been widely used to implement real-time controllers in nuclear RPSs (Reactor Protection Systems). Increasing complexity and maintenance cost, however, are now demanding more powerful and cost-effective implementation such as FPGA (Field-Programmable Gate Array). Abandoning all experience and knowledge accumulated over the decades and starting an all-new development approach is too risky for such safety-critical systems. This paper proposes an RPS software development process with a platform change from PLC to FPGA, while retaining all outputs from the established development. This paper transforms FBD designs of the PLC-based software development into a behaviorally-equivalent Verilog program, which is a starting point of a typical FPGA-based hardware development. We expect that the proposed software development process can bridge the gap between two software developing approaches with different platforms, such as PLC and FPGA. This paper also demonstrates its effectiveness using an example of a prototype version of a real-world RPS in Korea.

  13. A Research on Seamless Platform Change of Reactor Protection System From PLC to FPGA

    International Nuclear Information System (INIS)

    Yoo, Junbeom; Lee, Jonghoon; Lee, Jangsoo

    2013-01-01

    The PLC (Programmable Logic Controller) has been widely used to implement real-time controllers in nuclear RPSs (Reactor Protection Systems). Increasing complexity and maintenance cost, however, are now demanding more powerful and cost-effective implementation such as FPGA (Field-Programmable Gate Array). Abandoning all experience and knowledge accumulated over the decades and starting an all-new development approach is too risky for such safety-critical systems. This paper proposes an RPS software development process with a platform change from PLC to FPGA, while retaining all outputs from the established development. This paper transforms FBD designs of the PLC-based software development into a behaviorally-equivalent Verilog program, which is a starting point of a typical FPGA-based hardware development. We expect that the proposed software development process can bridge the gap between two software developing approaches with different platforms, such as PLC and FPGA. This paper also demonstrates its effectiveness using an example of a prototype version of a real-world RPS in Korea

  14. Kameleon Live: An Interactive Cloud Based Analysis and Visualization Platform for Space Weather Researchers

    Science.gov (United States)

    Pembroke, A. D.; Colbert, J. A.

    2015-12-01

    The Community Coordinated Modeling Center (CCMC) provides hosting for many of the simulations used by the space weather community of scientists, educators, and forecasters. CCMC users may submit model runs through the Runs on Request system, which produces static visualizations of model output in the browser, while further analysis may be performed off-line via Kameleon, CCMC's cross-language access and interpolation library. Off-line analysis may be suitable for power-users, but storage and coding requirements present a barrier to entry for non-experts. Moreover, a lack of a consistent framework for analysis hinders reproducibility of scientific findings. To that end, we have developed Kameleon Live, a cloud based interactive analysis and visualization platform. Kameleon Live allows users to create scientific studies built around selected runs from the Runs on Request database, perform analysis on those runs, collaborate with other users, and disseminate their findings among the space weather community. In addition to showcasing these novel collaborative analysis features, we invite feedback from CCMC users as we seek to advance and improve on the new platform.

  15. Simulation research about China Experimental Fast Reactor steam turboset based on Flowmaster platform

    International Nuclear Information System (INIS)

    Yan Hao; Tian Zhaofei

    2014-01-01

    In the third loop of China Experimental Fast Reactor (CEFR), steam turboset take an important role in converting heat energy into electric energy. However, turbo sets have not been operated on the condition of more than 40%P_0 (P_0 is full power) since they were installed. Thus it is necessary to make an analogue simulation. Based on the real models of turbo sets in CEFR, simulation models were created with the help of Flowmaster platform. By using such simulation models, a steady state result in full power circumstance was got, which is in accordance with design parameters. Meanwhile, a transient state simulation with operating condition ranging from full power to 40%P_0 was accomplished and a result which verifies part of performance and running conditions of turbo sets was got. The result of analogue simulation shows that based on Flowmaster platform, the running condition of simulation models can comply with design requirement, and offer reference values to the actual running. Such simulation models can also offer reference values to other simulation models in the third loop of CEFR. (authors)

  16. Robot-assisted surgery: an emerging platform for human neuroscience research

    Directory of Open Access Journals (Sweden)

    Anthony Michael Jarc

    2015-06-01

    Full Text Available Classic studies in human sensorimotor control use simplified tasks to uncover fundamental control strategies employed by the nervous system. Such simple tasks are critical for isolating specific features of motor, sensory, or cognitive processes, and for inferring causality between these features and observed behavioral changes. However, it remains unclear how these theories translate to complex sensorimotor tasks or to natural behaviors. Part of the difficulty in performing such experiments has been the lack of appropriate tools for measuring complex motor skills in real-world contexts. Robot-assisted surgery (RAS provides an opportunity to overcome these challenges by enabling unobtrusive measurements of user behavior. In addition, a continuum of tasks with varying complexity – from simple tasks such as those in classic studies to highly complex tasks such as a surgical procedure – can be studied using RAS platforms. Finally, RAS includes a diverse participant population of inexperienced users all the way to expert surgeons. In this perspective, we illustrate how the characteristics of RAS systems make them compelling platforms to extend many theories in human neuroscience, as well as, to develop new theories altogether.

  17. Research on systematization and advancement of shipbuilding production management for flexible and agile response for high value offshore platform

    Directory of Open Access Journals (Sweden)

    Young-Joo Song

    2011-09-01

    In this paper, I'm going to define a standard shipbuilding production management system by investigating the environment of domestic major shipbuilding companies. Also, I'm going to propose a unified ship production management and system for the operation of unified management through detail analysis of the activities and the data flow of ship production management. And, the system functions for the strategic approach of ship production management are investigated through the business administration tools such as performance pyramid, VDT and BSC. Lastly, the research of applying strategic KPI to the digital shipyard as virtual execution platform is conducted.

  18. Creating artificial reefs from decommissioned platforms in the North Sea: review of knowledge and proposed programme of research

    Energy Technology Data Exchange (ETDEWEB)

    Aabel, J.P.; Cripps, S.J.; Jensen, A.C.; Picken, G.

    1997-12-31

    This report relates to the case for research and development work on North Sea artificial reefs. There are potentially many benefits that can be derived from platform reefs, for example as an aid to increased fishing yield for commercial fishermen, a means of enhancing fish stocks and protecting habitat for physical damage. In addition there may be a reduction in decommissioning costs for the oil industry and in negative environmental impacts inherent with land-based decommissioning techniques. Negative impacts could be loss of fishing area and changes in the ecosystem. The report will be focused towards practically applicable results that will aid the decision making process. 129 refs., 13 figs., 18 tabs.

  19. Creating artificial reefs from decommissioned platforms in the North Sea: review of knowledge and proposed programme of research

    Energy Technology Data Exchange (ETDEWEB)

    Aabel, J P; Cripps, S J; Jensen, A C; Picken, G

    1998-12-31

    This report relates to the case for research and development work on North Sea artificial reefs. There are potentially many benefits that can be derived from platform reefs, for example as an aid to increased fishing yield for commercial fishermen, a means of enhancing fish stocks and protecting habitat for physical damage. In addition there may be a reduction in decommissioning costs for the oil industry and in negative environmental impacts inherent with land-based decommissioning techniques. Negative impacts could be loss of fishing area and changes in the ecosystem. The report will be focused towards practically applicable results that will aid the decision making process. 129 refs., 13 figs., 18 tabs.

  20. Based on the rainfall system platform raindrops research and analysis of pressure loss

    Science.gov (United States)

    Cao, Gang; Sun, Jian

    2018-01-01

    With the rapid development of China’s military career, land, sea and air force all services and equipment of modern equipment need to be in the rain test, and verify its might suffer during transportation, storage or use a different environment temperature lower water or use underwater, the water is derived from the heavy rain, the wind and rain, sprinkler system, splash water, water wheel, a violent shock waves or use underwater, etcTest the product performance and quality, under the condition of rainfall system platform in the process of development, how to control the raindrops pressure loss becomes the key to whether the system can simulate the real rainfall [1], this paper is according to the rainfall intensity, nozzle flow resistance, meet water flow of rain pressure loss calculation and analysis, and system arrangement of the optimal solution of rainfall is obtained [2].

  1. Research on Image Transmission System Based on 3G Communication Platform

    Directory of Open Access Journals (Sweden)

    Jingfeng Zang

    2014-07-01

    Full Text Available A wireless image real-time transmission system is designed by using 3G wireless communication platform and ARM + DSP embedded system. In the environment of 3G networks, the embedded equipment has realized the functions of coding, acquisition, network transmission, decoding and playing. It is realized for real-time video of intelligent control and video compression, storage and playback in the 3G embedded image transmission system. It is especially suitable for remote location or irregular cable network transmission conditions applications. It is shown that in the 3G network video files are transferred quickly. The real-time transmission of H.264 video is broadcasted smoothly, and color distortion is less. The server can control client by remote intelligent units.

  2. GRASS GIS: a peer-reviewed scientific platform and future research repository

    Science.gov (United States)

    Chemin, Yann; Petras, Vaclav; Petrasova, Anna; Landa, Martin; Gebbert, Sören; Zambelli, Pietro; Neteler, Markus; Löwe, Peter; Di Leo, Margherita

    2015-04-01

    Geographical Information System (GIS) is known for its capacity to spatially enhance the management of natural resources. While being often used as an analytical tool, it also represents a collaborative scientific platform to develop new algorithms. Thus, it is critical that GIS software as well as the algorithms are open and accessible to anybody [18]. We present how GRASS GIS, a free and open source GIS, is used by many scientists to implement and perform geoprocessing tasks. We will show how integrating scientific algorithms into GRASS GIS helps to preserve reproducibility of scientific results over time [15]. Moreover, subsequent improvements are tracked in the source code version control system and are immediately available to the public. GRASS GIS therefore acts as a repository of scientific peer-reviewed code, algorithm library, and knowledge hub for future generation of scientists. In the field of hydrology, with the various types of actual evapotranspiration (ET) models being developed in the last 20 years, it becomes necessary to inter-compare methods. Most of already published ETa models comparisons address few number of models, and small to medium areas [3, 6, 7, 22, 23]. With the large amount of remote sensing data covering the Earth, and the daily information available for the past ten years (i.e. Aqua/Terra-MODIS) for each pixel location, it becomes paramount to have a more complete comparison, in space and time. To address this new experimental requirement, a distributed computing framework was designed, and created [3, 4]. The design architecture was built from original satellite datasets to various levels of processing until reaching the requirement of various ETa models input dataset. Each input product is computed once and reused in all ETa models requiring such input. This permits standardization of inputs as much as possible to zero-in variations of models to the models internals/specificities. All of the ET models are available in the new

  3. Dynamic Gaming Platform (DGP)

    Science.gov (United States)

    2009-04-01

    GAMING PLATFORM (DGP) Lockheed Martin Corporation...YYYY) APR 09 2. REPORT TYPE Final 3. DATES COVERED (From - To) Jul 07 – Mar 09 4. TITLE AND SUBTITLE DYNAMIC GAMING PLATFORM (DGP) 5a...CMU Carnegie Mellon University DGP Dynamic Gaming Platform GA Genetic Algorithm IARPA Intelligence Advanced Research Projects Activity LM ATL Lockheed Martin Advanced Technology Laboratories PAINT ProActive INTelligence

  4. Mobile platform security

    CERN Document Server

    Asokan, N; Dmitrienko, Alexandra

    2013-01-01

    Recently, mobile security has garnered considerable interest in both the research community and industry due to the popularity of smartphones. The current smartphone platforms are open systems that allow application development, also for malicious parties. To protect the mobile device, its user, and other mobile ecosystem stakeholders such as network operators, application execution is controlled by a platform security architecture. This book explores how such mobile platform security architectures work. We present a generic model for mobile platform security architectures: the model illustrat

  5. tranSMART: An Open Source and Community-Driven Informatics and Data Sharing Platform for Clinical and Translational Research.

    Science.gov (United States)

    Athey, Brian D; Braxenthaler, Michael; Haas, Magali; Guo, Yike

    2013-01-01

    tranSMART is an emerging global open source public private partnership community developing a comprehensive informatics-based analysis and data-sharing cloud platform for clinical and translational research. The tranSMART consortium includes pharmaceutical and other companies, not-for-profits, academic entities, patient advocacy groups, and government stakeholders. The tranSMART value proposition relies on the concept that the global community of users, developers, and stakeholders are the best source of innovation for applications and for useful data. Continued development and use of the tranSMART platform will create a means to enable "pre-competitive" data sharing broadly, saving money and, potentially accelerating research translation to cures. Significant transformative effects of tranSMART includes 1) allowing for all its user community to benefit from experts globally, 2) capturing the best of innovation in analytic tools, 3) a growing 'big data' resource, 4) convergent standards, and 5) new informatics-enabled translational science in the pharma, academic, and not-for-profit sectors.

  6. Design of a Maglev Vibration Test Platform for the Research of Maglev Vehicle-girder Coupled Vibration Problem

    Directory of Open Access Journals (Sweden)

    Zhou Danfeng

    2017-01-01

    Full Text Available The maglev vehicle-girder coupled vibration problem has been encountered in many maglev test or commercial lines, which significantly degrade the performance of the maglev train. In previous research on the principle of the coupled vibration problem, it has been discovered that the fundamental model of the maglev girder can be simplified as a series of mass-spring resonators of different but related resonance frequencies, and that the stability of the vehicle-girder coupled system can be investigated by separately examining the stability of each mass-spring resonator – electromagnet coupled system. Based on this conclusion, a maglev test platform, which includes a single electromagnetic suspension control system, is built for experimental study of the coupled vibration problem. The guideway of the test platform is supported by a number of springs so as to change its flexibility. The mass of the guideway can also be changed by adjusting extra weights attached to it. By changing the flexibility and mass of the guideway, the rules of the maglev vehicle-girder coupled vibration problem are to be examined through experiments, and related theory on the vehicle-girder self-excited vibration proposed in previous research is also testified.

  7. Moving Virtual Research Environments from high maintenance Stovepipes to Multi-purpose Sustainable Service-oriented Science Platforms

    Science.gov (United States)

    Klump, Jens; Fraser, Ryan; Wyborn, Lesley; Friedrich, Carsten; Squire, Geoffrey; Barker, Michelle; Moloney, Glenn

    2017-04-01

    The researcher of today is likely to be part of a team distributed over multiple sites that will access data from an external repository and then process the data on a public or private cloud or even on a large centralised supercomputer. They are increasingly likely to use a mixture of their own code, third party software and libraries, or even access global community codes. These components will be connected into a Virtual Research Environments (VREs) that will enable members of the research team who are not co-located to actively work together at various scales to share data, models, tools, software, workflows, best practices, infrastructures, etc. Many VRE's are built in isolation: designed to meet a specific research program with components tightly coupled and not capable of being repurposed for other use cases - they are becoming 'stovepipes'. The limited number of users of some VREs also means that the cost of maintenance per researcher can be unacceptably high. The alternative is to develop service-oriented Science Platforms that enable multiple communities to develop specialised solutions for specific research programs. The platforms can offer access to data, software tools and processing infrastructures (cloud, supercomputers) through globally distributed, interconnected modules. In Australia, the Virtual Geophysics Laboratory (VGL) was initially built to enable a specific set of researchers in government agencies access to specific data sets and a limited number of tools, that is now rapidly evolving into a multi-purpose Earth science platform with access to an increased variety of data, a broader range of tools, users from more sectors and a diversity of computational infrastructures. The expansion has been relatively easy, because of the architecture whereby data, tools and compute resources are loosely coupled via interfaces that are built on international standards and accessed as services wherever possible. In recent years, investments in

  8. The VISPA internet platform for outreach, education and scientific research in various experiments

    Science.gov (United States)

    van Asseldonk, D.; Erdmann, M.; Fischer, B.; Fischer, R.; Glaser, C.; Heidemann, F.; Müller, G.; Quast, T.; Rieger, M.; Urban, M.; Welling, C.

    2015-12-01

    VISPA provides a graphical front-end to computing infrastructures giving its users all functionality needed for working conditions comparable to a personal computer. It is a framework that can be extended with custom applications to support individual needs, e.g. graphical interfaces for experiment-specific software. By design, VISPA serves as a multipurpose platform for many disciplines and experiments as demonstrated in the following different use-cases. A GUI to the analysis framework OFFLINE of the Pierre Auger collaboration, submission and monitoring of computing jobs, university teaching of hundreds of students, and outreach activity, especially in CERN's open data initiative. Serving heterogeneous user groups and applications gave us lots of experience. This helps us in maturing the system, i.e. improving the robustness and responsiveness, and the interplay of the components. Among the lessons learned are the choice of a file system, the implementation of websockets, efficient load balancing, and the fine-tuning of existing technologies like the RPC over SSH. We present in detail the improved server setup and report on the performance, the user acceptance and the realized applications of the system.

  9. Research and development of service robot platform based on artificial psychology

    Science.gov (United States)

    Zhang, Xueyuan; Wang, Zhiliang; Wang, Fenhua; Nagai, Masatake

    2007-12-01

    Some related works about the control architecture of robot system are briefly summarized. According to the discussions above, this paper proposes control architecture of service robot based on artificial psychology. In this control architecture, the robot can obtain the cognition of environment through sensors, and then be handled with intelligent model, affective model and learning model, and finally express the reaction to the outside stimulation through its behavior. For better understanding the architecture, hierarchical structure is also discussed. The control system of robot can be divided into five layers, namely physical layer, drives layer, information-processing and behavior-programming layer, application layer and system inspection and control layer. This paper shows how to achieve system integration from hardware modules, software interface and fault diagnosis. Embedded system GENE-8310 is selected as the PC platform of robot APROS-I, and its primary memory media is CF card. The arms and body of the robot are constituted by 13 motors and some connecting fittings. Besides, the robot has a robot head with emotional facial expression, and the head has 13 DOFs. The emotional and intelligent model is one of the most important parts in human-machine interaction. In order to better simulate human emotion, an emotional interaction model for robot is proposed according to the theory of need levels of Maslom and mood information of Siminov. This architecture has already been used in our intelligent service robot.

  10. Research and implementation of geography service bus in spatial data sharing platform

    Science.gov (United States)

    Zou, Zhiqiang; Nan, Jiang; Lin, Tao; Bai, Mingbai; He, Xingfu

    2006-10-01

    Geographic Information Systems, GIS, software has wide applications in business; however, implementation of the interoperability among the GIS has also become a challenge. This paper presents a solution based on Geography Service Bus that uses web services to achieve the interoperability among these heterogeneous GIS to allow users share the Geosciences data as well as access service. Referring to the abstract specification of OWS (OGC Web Services), the proposed solution adopts the SOA (Service-Oriented Architecture) when implementing SDSP (Spatial Data Sharing Platform). To accomplish this, a new abstract layer, GSB (Geography Service Bus), is created to provide standard interface. GSB extends ESB (Enterprise Service Bus) proposed by IBM and SUN, and combines the application in geography. GSB inherits the general features of ESB, such as interoperability, heterogeneity and service-oriented while offering unique functions like the high volume geo-data access and better management in geographic services. GSB includes the following JAVA implemented components: the management component of the geography registry service, the route component of the geography request service and the geographical business process component, etc. GSB plays an important role in SDSP and has been developed and successfully applied in the Data Center for Resources & Environmental Sciences in East China as a key project of Chinese Academy of Sciences. It has been observed that the introduction of GSB has tremendously improved both performance and interoperability of SDSP among heterogeneous GIS than traditional methods.

  11. A Web-Based Platform for Educating Researchers About Bioethics and Biobanking.

    Science.gov (United States)

    Sehovic, Ivana; Gwede, Clement K; Meade, Cathy D; Sodeke, Stephen; Pentz, Rebecca; Quinn, Gwendolyn P

    2016-06-01

    Participation in biobanking among individuals with familial risk for hereditary cancer (IFRs) and underserved/minority populations is vital for biobanking research. To address gaps in researcher knowledge regarding ethical concerns of these populations, we developed a web-based curriculum. Based on formative research and expert panel assessments, a curriculum and website was developed in an integrative, systematic manner. Researchers were recruited to evaluate the curriculum. Public health graduate students were recruited to pilot test the curriculum. All 14 researchers agreed the curriculum was easy to understand, adequately addressed the domains, and contained appropriate post-test questions. The majority evaluated the dialgoue animations as interesting and valuable. Twenty-two graduate students completed the curriculum, and 77 % improved their overall test score. A web-based curriculum is an acceptable and effective way to provide information to researchers about vulnerable populations' biobanking concerns. Future goals are to incorporate the curriculum with larger organizations.

  12. Tour Guide Robots: An Integrated Research and Design Platform to Prepare Engineering and Technology Students

    Science.gov (United States)

    Yelamarthi, Kumar

    2016-01-01

    Many interesting research and design questions occur at the intersections of traditional disciplines, yet most coursework and research programs for undergraduate engineering students are focused on one discipline. This leads to underutilization of the potential in better preparing students through multidisciplinary projects. Identifying this…

  13. Network cyberinfrastructure as a shared platform to support multi-site research

    Science.gov (United States)

    Multi-site research across the Long-term Agroecosystem Research (LTAR) network requires access to data and information. We present some existing examples where you can get data from across the network and summarize the rich inventory of measurements taken across LTAR sites. But data management suppo...

  14. Action Design Research for Social Innovation: Lessons from Designing a Health and Wellbeing Platform

    NARCIS (Netherlands)

    de Reuver, G.A.; Keijzer-Broers, W.J.W.

    2016-01-01

    IT artifacts play an important role in solving societal problems and realizing social innovations. Existing practice-inspired design science research (DSR) approaches, such as Action Design Research (ADR), do not consider social innovation as an explicit starting point for design iterations. In this

  15. Potential of nanotechnology as a delivery platform against tuberculosis: current research review.

    Science.gov (United States)

    Choudhary, S; Kusum Devi, V

    2015-03-28

    This review focusses on the current ongoing research in the field of tuberculosis comprising the resistant strains. It specifies a proper data analysis with results in concise form from areas gripping in: diagnostic nanotechnology, vaccine nanotechnology and the prime field of interest i.e., therapeutic nanotechnology. Primarily, therapeutic area recollects the research findings from advanced drug delivery (primary era) to the targeted drug delivery (modern era). The vaccine-based area derives the immune-specific targeting with enhanced emphasis on vaccine extraction and preparation of nanoparticles. Finally, the diagnostic area signifies the imaging techniques that may be employed in the diagnosis of TB. Not only that, there are some researches that emphasized on finding the comparable diagnostic differences between normal and resistant strains. With the advent of carbon nanotubes, metallic NPs, a newer hope has emerged out in diagnostic research, which may extend to therapeutic research applications too. Modifications of natural polymers, least or no use of organic solvents, size controlled NPs, optimized methodology, etc., are fields that need more effort to bypass toxicity. If above desired possibilities get the priority during research, it may lead to shift in the timeline towards much more oriented research. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Building a platform for scientific-research cooperation under circumstances of realized asymmetry of potential

    Directory of Open Access Journals (Sweden)

    Wiśniowski Witold

    2016-12-01

    Full Text Available Growing complexity of the environment arising both from the processes of globalization in world economy and from the development processes in Poland has become a strategic challenge for the Institute of Aviation. Significant disproportions of the potential of Poland, compared to Germany, United States, or China (especially in terms of the economic dimension and the adopted model for financing scientific research, as well as distant position of Polish universities on the scientific map of the world lead to the necessity to create a model for managing the Institute of Aviation based on internationalization of research and cooperation with leading scientific and (Ohio State University – OSU technological centres (General Electric – GE. The experiences of the Institute of Aviation show that what should be the basis of international competitiveness of research institutes is well educated scientific personnel, modern research infrastructure and competences of cooperation. A proof of this is 16-year-long strategic alliance (private-public partnership of the Institute and GE, cooperation with OSU and activities in European research consortia. The innovative dimension of scientific cooperation with OSU (2+2 formula, research internships, commission for predicting new directions of scientific research and other foreign partners allows the Institute of Aviation to achieve success in competition of international character.

  17. Product Platform Performance

    DEFF Research Database (Denmark)

    Munk, Lone

    The aim of this research is to improve understanding of platform-based product development by studying platform performance in relation to internal effects in companies. Platform-based product development makes it possible to deliver product variety and at the same time reduce the needed resources...... engaging in platform-based product development. Similarly platform assessment criteria lack empirical verification regarding relevance and sufficiency. The thesis focuses on • the process of identifying and estimating internal effects, • verification of performance of product platforms, (i...... experienced representatives from the different life systems phase systems of the platform products. The effects are estimated and modeled within different scenarios, taking into account financial and real option aspects. The model illustrates and supports estimation and quantification of internal platform...

  18. Fiscal 1999 achievement report on interuniversity coordination type research and development of industrial technology. Research and development of highly functional material designing platform; 1999 nendo kokino zairyo sekkei platform no kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    For the purpose of enabling prediction of structures and properties of polymeric materials by computer-assisted experiments, studies were conducted for putting new simulation technologies to practical application. Simulation technologies underwent research and development with working groups respectively dealing with the coarse-graining molecular dynamic method, dynamic mean field method, dispersed structure simulation, study of verification, and platform. The Faculty of Engineering, Yamagata University, succeeded in the development of a device enabling direct observation of crystallization under shear flow, which was for the construction of a material property database. The Graduate School of Frontier Sciences, University of Tokyo, developed a device for measuring dielectric relaxation under shear flow, by which findings were obtained concerning ion fluctuation and diffusion in a micellar system. The Institute of Industrial Science, University of Tokyo, studied pattern formation dynamics which involved viscoelastic phase separation in a polymeric solution whose composition was near critical. (NEDO)

  19. FACET as a Collaborative, Open Source UAS Research Platform, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — We build a tool that accelerates Research and Development (R where simulations at one university may be run with models and parameters provided by other users at...

  20. Requirements for data integration platforms in biomedical research networks: a reference model.

    Science.gov (United States)

    Ganzinger, Matthias; Knaup, Petra

    2015-01-01

    Biomedical research networks need to integrate research data among their members and with external partners. To support such data sharing activities, an adequate information technology infrastructure is necessary. To facilitate the establishment of such an infrastructure, we developed a reference model for the requirements. The reference model consists of five reference goals and 15 reference requirements. Using the Unified Modeling Language, the goals and requirements are set into relation to each other. In addition, all goals and requirements are described textually in tables. This reference model can be used by research networks as a basis for a resource efficient acquisition of their project specific requirements. Furthermore, a concrete instance of the reference model is described for a research network on liver cancer. The reference model is transferred into a requirements model of the specific network. Based on this concrete requirements model, a service-oriented information technology architecture is derived and also described in this paper.

  1. Digital platforms for research collaboration: using design science in developing a South African open knowledge repository

    CSIR Research Space (South Africa)

    van Biljon, J

    2017-05-01

    Full Text Available ) enabled collaboration through the design and development of a sustainable open knowledge repository (OKR) according to the design science research (DSR) paradigm. OKRs are tools used to support knowledge sharing and collaboration. The theoretical...

  2. US Forest Service Experimental Forests and Ranges Network: a continental research platform for catchment-scale research

    Science.gov (United States)

    Daniel Neary; Deborah Hayes; Lindsey Rustad; James Vose; Gerald Gottfried; Stephen Sebesteyn; Sherri Johnson; Fred Swanson; Mary Adams

    2012-01-01

    The US Forest Service initiated its catchment research program in 1909 with the first paired catchment study at Wagon Wheel Gap, Colorado, USA. It has since developed the Experimental Forests and Ranges Network, with over 80 long-term research study sites located across the contiguous USA, Alaska, Hawaii, and the Caribbean. This network provides a unique, powerful...

  3. CER Hub: An informatics platform for conducting comparative effectiveness research using multi-institutional, heterogeneous, electronic clinical data.

    Science.gov (United States)

    Hazlehurst, Brian L; Kurtz, Stephen E; Masica, Andrew; Stevens, Victor J; McBurnie, Mary Ann; Puro, Jon E; Vijayadeva, Vinutha; Au, David H; Brannon, Elissa D; Sittig, Dean F

    2015-10-01

    Comparative effectiveness research (CER) requires the capture and analysis of data from disparate sources, often from a variety of institutions with diverse electronic health record (EHR) implementations. In this paper we describe the CER Hub, a web-based informatics platform for developing and conducting research studies that combine comprehensive electronic clinical data from multiple health care organizations. The CER Hub platform implements a data processing pipeline that employs informatics standards for data representation and web-based tools for developing study-specific data processing applications, providing standardized access to the patient-centric electronic health record (EHR) across organizations. The CER Hub is being used to conduct two CER studies utilizing data from six geographically distributed and demographically diverse health systems. These foundational studies address the effectiveness of medications for controlling asthma and the effectiveness of smoking cessation services delivered in primary care. The CER Hub includes four key capabilities: the ability to process and analyze both free-text and coded clinical data in the EHR; a data processing environment supported by distributed data and study governance processes; a clinical data-interchange format for facilitating standardized extraction of clinical data from EHRs; and a library of shareable clinical data processing applications. CER requires coordinated and scalable methods for extracting, aggregating, and analyzing complex, multi-institutional clinical data. By offering a range of informatics tools integrated into a framework for conducting studies using EHR data, the CER Hub provides a solution to the challenges of multi-institutional research using electronic medical record data. Copyright © 2015. Published by Elsevier Ireland Ltd.

  4. Ubuntunet Alliance: A Collaborative Research Platform for Sharing of Technological Tools for Eradication of Brain Drain

    Directory of Open Access Journals (Sweden)

    Jameson Mbale

    2012-12-01

    Full Text Available The UbuntuNet Alliance Alliance is well-placed to facilitate interaction between education and research institutions and the African academic and researcher in the Diaspora so that together they can strengthen research that will exploit new technological tools and increase the industrial base. It is envisaged that the Alliance will become an important vehicle for linkages that will facilitate repatriation of scientific knowledge and skills to Africa and even help reduce and eventually eradicate the brain drain which has taken so many excellent intellectuals to the developed world. As organisational vehicles for inter-institutional collaboration both established and emerging NRENs can play a critical role in reversing these trends and in mitigating what appears to be the negative impact of the brain drain.

  5. Games as a Platform for Student Participation in Authentic Scientific Research

    DEFF Research Database (Denmark)

    Magnussen, Rikke; Damgaard Hansen, Sidse; Planke, Tilo

    2014-01-01

    for student-research collaboration is to investigate if and how this type of game concept can strengthen authentic experimental practice and the creation of new knowledge in science education. Researchers and game developers tested the game in three separate high school classes (Class 1, 2, and 3). The tests...... were documented using video observations of students playing the game, qualitative interviews, and qualitative and quantitative questionnaires. The focus of the tests has been to study players' motivation and their experience of learning through participation in authentic scientific inquiry....... In questionnaires conducted in the two first test classes students found that the aspects of doing “real scientific research” and solving physics problems were the more interesting aspects of playing the game. However, designing a game that facilitates professional research collaboration while simultaneously...

  6. Patient-Derived Xenograft Models : An Emerging Platform for Translational Cancer Research

    NARCIS (Netherlands)

    Hidalgo, Manuel; Amant, Frederic; Biankin, Andrew V.; Budinska, Eva; Byrne, Annette T.; Caldas, Carlos; Clarke, Robert B.; de Jong, Steven; Jonkers, Jos; Maelandsmo, Gunhild Mari; Roman-Roman, Sergio; Seoane, Joan; Trusolino, Livio; Villanueva, Alberto

    Recently, there has been an increasing interest in the development and characterization of patient-derived tumor xenograft (PDX) models for cancer research. PDX models mostly retain the principal histologic and genetic characteristics of their donor tumor and remain stable across passages. These

  7. Museum-University Partnerships as a New Platform for Public Engagement with Scientific Research

    Science.gov (United States)

    Bell, Jamie; Chesebrough, David; Cryan, Jason; Koster, Emlyn

    2016-01-01

    A growing trend in natural history museums, science museums, and science centers is the establishment of innovative new partnerships with universities to bring scientific research to the public in compelling and transformative ways. The strengths of both kinds of institutions are leveraged in effective and publicly visible programs, activities,…

  8. 40 Years of research at Risoe: A platform for the future - interacting with industry and society

    Energy Technology Data Exchange (ETDEWEB)

    Rosendahl, Lis; Lading, Lars [eds.

    1998-08-01

    Risoe`s 40th anniversary was celebrated June 3, 1998 by a symposium held at Risoe. The interaction of research at Risoe with academia and industry was presented in both national and international perspective. Most of the presentations are in English, a few in Danish. (au)

  9. When Complexity Theory Meets Critical Realism: A Platform for Research on Initial Teacher Education

    Science.gov (United States)

    Cochran-Smith, Marilyn; Ell, Fiona; Grudnoff, Lexie; Ludlow, Larry; Haigh, Mavis; Hill, Mary

    2014-01-01

    Many scholars have concluded that teacher education research needs to take a complex view, resist simplification, and account more fully for teacher education's contexts and processes as well as its impact on teacher candidates' and school students' learning (Cochran-Smith & Zeichner, 2005; Grossman & McDonald, 2008; Opfer & Pedder,…

  10. Accelerating translational research by clinically driven development of an informatics platform--a case study.

    Directory of Open Access Journals (Sweden)

    Imad Abugessaisa

    Full Text Available Translational medicine is becoming increasingly dependent upon data generated from health care, clinical research, and molecular investigations. This increasing rate of production and diversity in data has brought about several challenges, including the need to integrate fragmented databases, enable secondary use of patient clinical data from health care in clinical research, and to create information systems that clinicians and biomedical researchers can readily use. Our case study effectively integrates requirements from the clinical and biomedical researcher perspectives in a translational medicine setting. Our three principal achievements are (a a design of a user-friendly web-based system for management and integration of clinical and molecular databases, while adhering to proper de-identification and security measures; (b providing a real-world test of the system functionalities using clinical cohorts; and (c system integration with a clinical decision support system to demonstrate system interoperability. We engaged two active clinical cohorts, 747 psoriasis patients and 2001 rheumatoid arthritis patients, to demonstrate efficient query possibilities across the data sources, enable cohort stratification, extract variation in antibody patterns, study biomarker predictors of treatment response in RA patients, and to explore metabolic profiles of psoriasis patients. Finally, we demonstrated system interoperability by enabling integration with an established clinical decision support system in health care. To assure the usefulness and usability of the system, we followed two approaches. First, we created a graphical user interface supporting all user interactions. Secondly we carried out a system performance evaluation study where we measured the average response time in seconds for active users, http errors, and kilobits per second received and sent. The maximum response time was found to be 0.12 seconds; no server or client errors of any

  11. Development of a Common Format of Questionnaire Tests for a Web-based Platform of Population and Experimental Psychological Research

    Directory of Open Access Journals (Sweden)

    Nikulchev Evgeny

    2018-01-01

    Full Text Available A web platform for psychological research needs a single format of questionnaire tests to ensure interaction between its components. The study proposes a general test structure, variant questions, variations in response types, and an embedded domain-specific language for computations. The use of JSON is proposed and justified to store the hierarchical structure of the questionnaire test, and JSON Schema is defined as a technology suitable for the formation of the standard. From the considered validation instruments for compliance with the standard described in JSON Schema, ajv was defined as the most applicable to the task. To build the documentation, Doca is relevant, but this tool needs to be modified to meet the requirements of the task.

  12. Fishpathogens.eu/noda: a free and handy online platform for Betanodavirus targeted research and data sharing.

    Science.gov (United States)

    Mikkelsen, S S; Panzarin, V; Jonstrup, S P; Bigarré, L; Baud, M; Gray, T; Agapow, P-M; Olesen, N J

    2015-08-01

    Viral nervous necrosis (VNN) is a severe neuropathological disease affecting a broad variety of finfish species worldwide. The causative agents of VNN are small viruses with a bi-segmented RNA genome known as betanodaviruses. At least four species with distinct but yet insufficiently characterized epidemiological features are recognized. The spread of VNN to an increasing number of host species, its wide geographic extent and its economical and ecological impacts justify the importance of collating as much molecular data as possible for tracing the origin of viral isolates and highlight the need for a freely accessible tool for epidemiological and molecular data sharing and consultation. For this purpose, we established a web-based specific database using the www.fishpathogens.eu platform, with the aim of collecting molecular and epidemiological information on VNN viruses, with relevance to their control, management and research studies. © 2015 John Wiley & Sons Ltd.

  13. National Mesothelioma Virtual Bank: A Platform for Collaborative Research and Mesothelioma Biobanking Resource to Support Translational Research.

    Science.gov (United States)

    Amin, Waqas; Parwani, Anil V; Melamed, Jonathan; Flores, Raja; Pennathur, Arjun; Valdivieso, Federico; Whelan, Nancy B; Landreneau, Rodeny; Luketich, James; Feldman, Michael; Pass, Harvey I; Becich, Michael J

    2013-01-01

    The National Mesothelioma Virtual Bank (NMVB), developed six years ago, gathers clinically annotated human mesothelioma specimens for basic and clinical science research. During this period, this resource has greatly increased its collection of specimens by expanding the number of contributing academic health centers including New York University, University of Pennsylvania, University of Pittsburgh Medical Center, and Mount Sinai School of Medicine. Marketing efforts at both national and international annual conferences increase awareness and availability of the mesothelioma specimens at no cost to approved investigators, who query the web-based NMVB database for cumulative and appropriate patient clinicopathological information on the specimens. The data disclosure and specimen distribution protocols are tightly regulated to maintain compliance with participating institutions' IRB and regulatory committee reviews. The NMVB currently has over 1120 annotated cases available for researchers, including paraffin embedded tissues, fresh frozen tissue, tissue microarrays (TMA), blood samples, and genomic DNA. In addition, the resource offers expertise and assistance for collaborative research. Furthermore, in the last six years, the resource has provided hundreds of specimens to the research community. The investigators can request specimens and/or data by submitting a Letter of Intent (LOI) that is evaluated by NMVB research evaluation panel (REP).

  14. The safety R and D for GEN-IV reactors in the European nuclear energy technology platform strategic research agenda

    International Nuclear Information System (INIS)

    Bruna, G.

    2009-01-01

    In the fall 2007 EC launched the Sustainable Nuclear Energy Technology Platform (SNE-TP). The SNE-TP governing board set-up three working groups (WG): 1) Strategic Research Agenda (SRA) WG, in charge of drafting road-maps to support research, development and demonstration for current and future NPPs; 2) Deployment Strategy (DS) WG, in charge of defining the research road-map implementation and 3) Education, Training and Knowledge management (ETKM) WG, which was aimed at issuing proposal to reinforce European education and attract young in the nuclear field. The SRA WG was mandated to prepare the SRA vision document based on the preliminary road-map sketched in the document published by the Commission earlier in 2007. The SRA WG was originally organized in 5 sub-groups covering specific topics (1) GEN II and III, III+, including Advanced LWR, 2) Advanced Fuel Cycle for waste minimization and resource optimization; 3) GEN IV Fast Systems (SFR, LFR, GFR, ADS); 4) GEN IV (V) HTR and non-electricity-production applications; 5) New Nuclear Large Research Infrastructures) and 5 other sub-groups dealing with more generic cross-cutting research activities applicable to many specific topics, namely: 1) Structural material research; 2) modeling, simulation and methods, including physical data and tools and means for qualification and validation; 3) Reactor Safety, including severe accidents and human factor; 4) Advanced Driver and Minor Actinide Fuels: science and properties; 5) Pre-normative Research, Codes and Standards.The present paper is mainly aimed at summarizing the content of the SRA Safety sub-chapter focusing on GEN-IV aspects

  15. E-research platform of EPOS Thematic Core Service "ANTHROPOGENIC HAZARDS"

    Science.gov (United States)

    Orlecka-Sikora, Beata; Lasocki, Stanisław; Grasso, Jean Robert; Schmittbuhl, Jean; Kwiatek, Grzegorz; Garcia, Alexander; Cassidy, Nigel; Sterzel, Mariusz; Szepieniec, Tomasz; Dineva, Savka; Biggare, Pascal; Saccorotti, Gilberto; Sileny, Jan; Fischer, Tomas

    2016-04-01

    EPOS Thematic Core Service ANTHROPOGENIC HAZARDS (TCS AH) aims to create new research opportunities in the field of anthropogenic hazards evoked by exploitation of georesources. TCS AH, based on the prototype built in the framework of the IS-EPOS project (https://tcs.ah-epos.eu/), financed from Polish structural funds (POIG.02.03.00-14-090/13-00), is being further developed within EPOS IP project (H2020-INFRADEV-1-2015-1, INFRADEV-3-2015). TCS AH is designed as a functional e-research environment to ensure a researcher the maximum possible freedom for in silico experimentation by providing a virtual laboratory in which researcher will be able to create own workspace with own processing streams. The unique integrated RI is: (i) data gathered in the so- called "episodes", comprehensively describing a geophysical process, induced or triggered by human technological activity, which under certain circumstances can become hazardous for people, infrastructure and the environment and (ii) problem-oriented, specific high-level services, with the particular attention devoted to methods analyzing correlations between technology, geophysical response and resulting hazard. Services to be implemented are grouped within six blocks: (1) Basic services for data integration and handling; (2) Services for physical models of stress/strain changes over time and space as driven by geo-resource production; (3) Services for analysing geophysical signals; (4) Services to extract the relation between technological operations and observed induced seismic/deformation; (5) Services to quantitative probabilistic assessments of anthropogenic seismic hazard - statistical properties of anthropogenic seismic series and their dependence on time-varying anthropogenesis; ground motion prediction equations; stationary and time-dependent probabilistic seismic hazard estimates, related to time-changeable technological factors inducing the seismic process; (6) Simulator for Multi

  16. Patient Derived Xenograft Models: An Emerging Platform for Translational Cancer Research

    Science.gov (United States)

    Hidalgo, Manuel; Amant, Frederic; Biankin, Andrew V.; Budinská, Eva; Byrne, Annette T.; Caldas, Carlos; Clarke, Robert B.; de Jong, Steven; Jonkers, Jos; Mælandsmo, Gunhild Mari; Roman-Roman, Sergio; Seoane, Joan; Trusolino, Livio; Villanueva, Alberto

    2014-01-01

    Recently, there has been increasing interest in the development and characterization of patient derived tumor xenograft (PDX) models for cancer research. PDX models mostly retain the principal histological and genetic characteristics of their donor tumor and remain stable across passages. These models have been shown to be predictive of clinical outcomes and are being used for preclinical drug evaluation, biomarker identification, biological studies, and personalized medicine strategies. This paper summarizes the current state of the art in this field including methodological issues, available collections, practical applications, challenges and shortcoming, and future directions, and introduces a European consortium of PDX models. PMID:25185190

  17. Chemistry and the worm: Caenorhabditis elegans as a platform for integrating chemical and biological research.

    Science.gov (United States)

    Hulme, S Elizabeth; Whitesides, George M

    2011-05-16

    This Review discusses the potential usefulness of the worm Caenorhabditis elegans as a model organism for chemists interested in studying living systems. C. elegans, a 1 mm long roundworm, is a popular model organism in almost all areas of modern biology. The worm has several features that make it attractive for biology: it is small (1000 cells), transparent, and genetically tractable. Despite its simplicity, the worm exhibits complex phenotypes associated with multicellularity: the worm has differentiated cells and organs, it ages and has a well-defined lifespan, and it is capable of learning and remembering. This Review argues that the balance between simplicity and complexity in the worm will make it a useful tool in determining the relationship between molecular-scale phenomena and organism-level phenomena, such as aging, behavior, cognition, and disease. Following an introduction to worm biology, the Review provides examples of current research with C. elegans that is chemically relevant. It also describes tools-biological, chemical, and physical-that are available to researchers studying the worm. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Developing an Open Source, Reusable Platform for Distributed Collaborative Information Management in the Early Detection Research Network

    Science.gov (United States)

    Hart, Andrew F.; Verma, Rishi; Mattmann, Chris A.; Crichton, Daniel J.; Kelly, Sean; Kincaid, Heather; Hughes, Steven; Ramirez, Paul; Goodale, Cameron; Anton, Kristen; hide

    2012-01-01

    For the past decade, the NASA Jet Propulsion Laboratory, in collaboration with Dartmouth University has served as the center for informatics for the Early Detection Research Network (EDRN). The EDRN is a multi-institution research effort funded by the U.S. National Cancer Institute (NCI) and tasked with identifying and validating biomarkers for the early detection of cancer. As the distributed network has grown, increasingly formal processes have been developed for the acquisition, curation, storage, and dissemination of heterogeneous research information assets, and an informatics infrastructure has emerged. In this paper we discuss the evolution of EDRN informatics, its success as a mechanism for distributed information integration, and the potential sustainability and reuse benefits of emerging efforts to make the platform components themselves open source. We describe our experience transitioning a large closed-source software system to a community driven, open source project at the Apache Software Foundation, and point to lessons learned that will guide our present efforts to promote the reuse of the EDRN informatics infrastructure by a broader community.

  19. Temperature profile from NOAA Ship RESEARCHER and other platforms as part of the ARP (Global Atmospheric Research Program) Atlantic Tropical Experiment from 1974-08-28 to 1974-09-20 (NODC Accession 7800314)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using BT and XBT from NOAA Ship RESEARCHER and other platforms in the TOGA area - Atlantic from 28 August 1974 to 20...

  20. Comparison Evaluations of VRF and RTU Systems Performance on Flexible Research Platform

    Directory of Open Access Journals (Sweden)

    Je-hyeon Lee

    2018-01-01

    Full Text Available The energy performance of a variable refrigerant flow (VRF system was evaluated using an occupancy-emulated research building in the southeastern region of the United States. Full- and part-load performance of the VRF system in heating and cooling seasons was compared with a conventional rooftop unit (RTU variable-air-volume system with electric resistance heating. During both the heating and cooling seasons, full- and part-load conditions (i.e., 100%, 75%, and 50% thermal loads were maintained alternately for 2 to 3 days each, and the energy use, thermal conditions, and coefficient of performance (COP for the RTU and VRF system were measured. During the cooling season, the VRF system had an average COP of 4.2, 3.9, and 3.7 compared with 3.1, 3.0, and 2.5 for the RTU system under 100%, 75%, and 50% load conditions and resulted in estimated energy savings of 30%, 37%, and 47%, respectively. During the heating season, the VRF system had an average COP ranging from 1.2 to 2.0, substantially higher than the COPs of the RTU system, and resulted in estimated energy savings of 51%, 47%, and 27% under the three load conditions, respectively.

  1. An overview of the severe accident research activities within the LACOMERA platform at the Forschungszentrum Karlsruhe

    International Nuclear Information System (INIS)

    Miassoedov, A.; Alsmeyer, H.; Meyer, L.; Steinbrueck, M.; Tromm, W.

    2006-01-01

    The LACOMERA project at the Forschungszentrum Karlsruhe, Germany, is a 4 year action within the 5th Framework Programme of the EU which started in September 2002. Overall objective of the project is to offer research institutions from the EU member countries and associated states access to four large-scale experimental facilities QUENCH, LIVE, DISCO, and COMET. These facilities can be used to investigate core melt scenarios from the beginning of core degradation to melt formation and relocation in the vessel, possible melt dispersion to the reactor cavity, and finally corium concrete interaction and corium coolability in the reactor cavity. The paper summarises the main results obtained in the following experiments performed up to now. QUENCH-L1: Impact of air ingression on core degradation. The test provides unique data for the investigation of air ingress phenomenology in conditions as representative of a spent fuel pool accident as possible; QUENCH-L2: Boil-off of a flooded bundle. The test is of a generic interest for all reactor types, provided a link between the severe accident and design basis areas, and would deliver oxidation and thermal hydraulic data at high temperatures. DISCO-L1: Thermal hydraulic behaviour of the corium melt dispersion neglecting the chemical effects such as hydrogen generation and combustion. COMET-L1: Long-term 2D concrete ablation in a siliceous concrete cavity at intermediate decay heat power level with a top flooding phase after a phase of dry concrete erosion. COMET-L2: Investigation of long-term melt-concrete interaction of metallic corium in a cylindrical siliceous concrete cavity under dry conditions with decay heat simulation of intermediate power during the first test phase, and subsequently at reduced power during the second test phase. (author)

  2. Development of system design and seismic performance evaluation for reactor pool working platform of a research reactor

    International Nuclear Information System (INIS)

    Kwag, Shinyoung; Lee, Jong-Min; Oh, Jinho; Ryu, Jeong-Soo

    2014-01-01

    Highlights: • Design of reactor pool working platform (RPWP) is newly proposed for an open-tank-in-pool type research reactor. • Main concept of RPWP is to minimize the pool top radiation level. • Framework for seismic performance evaluation of nuclear SSCs in a deterministic and a probabilistic manner is proposed. • Structural integrity, serviceability, and seismic margin of the RPWP are evaluated during and after seismic events. -- Abstract: The reactor pool working platform (RPWP) has been newly designed for an open-tank-in-pool type research reactor, and its seismic response, structural integrity, serviceability, and seismic margin have been evaluated during and after seismic events in this paper. The main important concept of the RPWP is to minimize the pool top radiation level by physically covering the reactor pool of the open-tank-in-pool type research reactor and suppressing the rise of flow induced by the primary cooling system. It is also to provide easy handling of the irradiated objects under the pool water by providing guide tubes and refueling cover to make the radioisotopes irradiated and protect the reactor structure assembly. For this concept, the new three dimensional design model of the RPWP is established for manufacturing, installation and operation, and the analytical model is developed to analyze the seismic performance. Since it is submerged under and influenced by water, the hydrodynamic effect is taken into account by using the hydrodynamic added mass method. To investigate the dynamic characteristics of the RPWP, a modal analysis of the developed analytical model is performed. To evaluate the structural integrity and serviceability of the RPWP, the response spectrum analysis and response time history analysis have been performed under the static load and the seismic load of a safe shutdown earthquake (SSE). Their stresses are analyzed for the structural integrity. The possibility of an impact between the RPWP and the most

  3. Prioritizing research for integrated implementation of early childhood development and maternal, newborn, child and adolescent health and nutrition platforms.

    Science.gov (United States)

    Sharma, Renee; Gaffey, Michelle F; Alderman, Harold; Bassani, Diego G; Bogard, Kimber; Darmstadt, Gary L; Das, Jai K; de Graft-Johnson, Joseph E; Hamadani, Jena D; Horton, Susan; Huicho, Luis; Hussein, Julia; Lye, Stephen; Pérez-Escamilla, Rafael; Proulx, Kerrie; Marfo, Kofi; Mathews-Hanna, Vanessa; Mclean, Mireille S; Rahman, Atif; Silver, Karlee L; Singla, Daisy R; Webb, Patrick; Bhutta, Zulfiqar A

    2017-06-01

    Existing health and nutrition services present potential platforms for scaling up delivery of early childhood development (ECD) interventions within sensitive windows across the life course, especially in the first 1000 days from conception to age 2 years. However, there is insufficient knowledge on how to optimize implementation for such strategies in an integrated manner. In light of this knowledge gap, we aimed to systematically identify a set of integrated implementation research priorities for health, nutrition and early child development within the 2015 to 2030 timeframe of the Sustainable Development Goals (SDGs). We applied the Child Health and Nutrition Research Initiative method, and consulted a diverse group of global health experts to develop and score 57 research questions against five criteria: answerability, effectiveness, deliverability, impact, and effect on equity. These questions were ranked using a research priority score, and the average expert agreement score was calculated for each question. The research priority scores ranged from 61.01 to 93.52, with a median of 82.87. The average expert agreement scores ranged from 0.50 to 0.90, with a median of 0.75. The top-ranked research question were: i) "How can interventions and packages to reduce neonatal mortality be expanded to include ECD and stimulation interventions?"; ii) "How does the integration of ECD and MNCAH&N interventions affect human resource requirements and capacity development in resource-poor settings?"; and iii) "How can integrated interventions be tailored to vulnerable refugee and migrant populations to protect against poor ECD and MNCAH&N outcomes?". Most highly-ranked research priorities varied across the life course and highlighted key aspects of scaling up coverage of integrated interventions in resource-limited settings, including: workforce and capacity development, cost-effectiveness and strategies to reduce financial barriers, and quality assessment of programs

  4. Research on systematization and advancement of shipbuilding production management for flexible and agile response for high value offshore platform

    Science.gov (United States)

    Song, Young-Joo; Woo, Jong-Hun; Shin, Jong-Gye

    2011-09-01

    Recently, the speed of change related with enterprise management is getting faster than ever owing to the competition among companies, technique diffusion, shortening of product lifecycle, excessive supply of market. For the example, the compliance condition (such as delivery date, product quality, etc.) from the ship owner is getting complicated and the needs for the new product such as FPSO, FSRU are coming to fore. This paradigm shift emphasize the rapid response rather than the competitive price, flexibility and agility rather than effective and optimal perspective for the domestic shipbuilding company. So, domestic shipbuilding companies have to secure agile and flexible ship production environment that could respond change of market and requirements of customers in order to continue a competitive edge in the world market. In this paper, I'm going to define a standard shipbuilding production management system by investigating the environment of domestic major shipbuilding companies. Also, I'm going to propose a unified ship production management and system for the operation of unified management through detail analysis of the activities and the data flow of ship production management. And, the system functions for the strategic approach of ship production management are investigated through the business administration tools such as performance pyramid, VDT and BSC. Lastly, the research of applying strategic KPI to the digital shipyard as virtual execution platform is conducted.

  5. Principles and Best Practices Emerging from Data Basin: A Data Platform Supporting Scientific Research and Landscape Conservation Planning

    Science.gov (United States)

    Comendant, T.; Strittholt, J. R.; Ward, B. C.; Bachelet, D. M.; Grossman, D.; Stevenson-Molnar, N.; Henifin, K.; Lundin, M.; Marvin, T. S.; Peterman, W. L.; Corrigan, G. N.; O'Connor, K.

    2013-12-01

    A multi-disciplinary team of scientists, software engineers, and outreach staff at the Conservation Biology Institute launched an open-access, web-based spatial data platform called Data Basin (www.databasin.org) in 2010. Primarily built to support research and environmental resource planning, Data Basin provides the capability for individuals and organizations to explore, create, interpret, and collaborate around their priority topics and geographies. We used a stakeholder analysis to assess the needs of data consumers/produces and help prioritize primary and secondary audiences. Data Basin's simple and user-friendly interface makes mapping and geo-processing tools more accessible to less technical audiences. Input from users is considered in system planning, testing, and implementation. The team continually develops using an agile software development approach, which allows new features, improvements, and bug fixes to be deployed to the live system on a frequent basis. The data import process is handled through administrative approval and Data Basin requires spatial data (biological, physical, and socio-economic) to be well-documented. Outreach and training is used to convey the scope and appropriate use of the scientific information and available resources.

  6. Developing a Cloud-Based Online Geospatial Information Sharing and Geoprocessing Platform to Facilitate Collaborative Education and Research

    Science.gov (United States)

    Yang, Z. L.; Cao, J.; Hu, K.; Gui, Z. P.; Wu, H. Y.; You, L.

    2016-06-01

    Efficient online discovering and applying geospatial information resources (GIRs) is critical in Earth Science domain as while for cross-disciplinary applications. However, to achieve it is challenging due to the heterogeneity, complexity and privacy of online GIRs. In this article, GeoSquare, a collaborative online geospatial information sharing and geoprocessing platform, was developed to tackle this problem. Specifically, (1) GIRs registration and multi-view query functions allow users to publish and discover GIRs more effectively. (2) Online geoprocessing and real-time execution status checking help users process data and conduct analysis without pre-installation of cumbersome professional tools on their own machines. (3) A service chain orchestration function enables domain experts to contribute and share their domain knowledge with community members through workflow modeling. (4) User inventory management allows registered users to collect and manage their own GIRs, monitor their execution status, and track their own geoprocessing histories. Besides, to enhance the flexibility and capacity of GeoSquare, distributed storage and cloud computing technologies are employed. To support interactive teaching and training, GeoSquare adopts the rich internet application (RIA) technology to create user-friendly graphical user interface (GUI). Results show that GeoSquare can integrate and foster collaboration between dispersed GIRs, computing resources and people. Subsequently, educators and researchers can share and exchange resources in an efficient and harmonious way.

  7. Microfluidic platform for electrophysiological recordings from host-stage hookworm and Ascaris suum larvae: A new tool for anthelmintic research

    Directory of Open Access Journals (Sweden)

    Janis C. Weeks

    2016-12-01

    Full Text Available The screening of candidate compounds and natural products for anthelmintic activity is important for discovering new drugs against human and animal parasites. We previously validated in Caenorhabditis elegans a microfluidic device (‘chip’ that records non-invasively the tiny electrophysiological signals generated by rhythmic contraction (pumping of the worm's pharynx. These electropharyngeograms (EPGs are recorded simultaneously from multiple worms per chip, providing a medium-throughput readout of muscular and neural activity that is especially useful for compounds targeting neurotransmitter receptors and ion channels. Microfluidic technologies have transformed C. elegans research and the goal of the current study was to validate hookworm and Ascaris suum host-stage larvae in the microfluidic EPG platform. Ancylostoma ceylanicum and A. caninum infective L3s (iL3s that had been activated in vitro generally produced erratic EPG activity under the conditions tested. In contrast, A. ceylanicum L4s recovered from hamsters exhibited robust, sustained EPG activity, consisting of three waveforms: (1 conventional pumps as seen in other nematodes; (2 rapid voltage deflections, associated with irregular contractions of the esophagus and openings of the esophogeal-intestinal valve (termed a ‘flutter’; and (3 hybrid waveforms, which we classified as pumps. For data analysis, pumps and flutters were combined and termed EPG ‘events.’ EPG waveform identification and analysis were performed semi-automatically using custom-designed software. The neuromodulator serotonin (5-hydroxytryptamine; 5HT increased EPG event frequency in A. ceylanicum L4s at an optimal concentration of 0.5 mM. The anthelmintic drug ivermectin (IVM inhibited EPG activity in a concentration-dependent manner. EPGs from A. suum L3s recovered from pig lungs exhibited robust pharyngeal pumping in 1 mM 5HT, which was inhibited by IVM. These experiments validate the use of A

  8. Payment Platform

    DEFF Research Database (Denmark)

    Hjelholt, Morten; Damsgaard, Jan

    2012-01-01

    thoroughly and substitute current payment standards in the decades to come. This paper portrays how digital payment platforms evolve in socio-technical niches and how various technological platforms aim for institutional attention in their attempt to challenge earlier platforms and standards. The paper...... applies a co-evolutionary multilevel perspective to model the interplay and processes between technology and society wherein digital payment platforms potentially will substitute other payment platforms just like the credit card negated the check. On this basis this paper formulate a multilevel conceptual...

  9. EURESCOM Services Platform

    NARCIS (Netherlands)

    Nieuwenhuis, Lambertus Johannes Maria; van Halteren, Aart

    1999-01-01

    This paper presents the results of the EURESCOM Project 715. In February 1999, a large team of researchers from six European public network operators completed a two year period of cooperative experiments on a TINA-based environment, called the EURESCOM Services Platform (ESP). This platform

  10. The strategic research agenda of the Technology Platform Photonics21: European component industry for broadband communications and the FP 7

    Science.gov (United States)

    Thylén, Lars

    2006-07-01

    The design and manufacture of components and systems underpin the European and indeed worldwide photonics industry. Optical materials and photonic components serve as the basis for systems building at different levels of complexity. In most cases, they perform a key function and dictate the performance of these systems. New products and processes will generate economic activity for the European photonics industry into the 21 st century. However, progress will rely on Europe's ability to develop new and better materials, components and systems. To achieve success, photonic components and systems must: •be reliable and inexpensive •be generic and adaptable •offer superior functionality •be innovative and protected by Intellectual Property •be aligned to market opportunities The challenge in the short-, medium-, and long-term is to put a coordinating framework in place which will make the European activity in this technology area competitive as compared to those in the US and Asia. In the short term the aim should be to facilitate the vibrant and profitable European photonics industry to further develop its ability to commercialize advances in photonic related technologies. In the medium and longer terms the objective must be to place renewed emphasis on materials research and the design and manufacturing of key components and systems to form the critical link between science endeavour and commercial success. All these general issues are highly relevant for the component intensive broadband communications industry. Also relevant for this development is the convergence of data and telecom, where the low cost of data com meets with the high reliability requirements of telecom. The text below is to a degree taken form the Strategic Research Agenda of the Technology Platform Photonics 21 [1], as this contains a concerted effort to iron out a strategy for EU in the area of photonics components and systems.

  11. Design and Research on Platform to Enhance College Students’ Art Appreciation Capability Based on Modern Information Technology

    Directory of Open Access Journals (Sweden)

    Shen Xifei

    2015-01-01

    Full Text Available Nowadays, with the rapid development of modern information technology, the college students could not preferably choose and learn to enhance their own art appreciation capability. Therefore, the colleges and universities have a more urgent desire to organize, develop and provide a good platform to enhance the college students’ art appreciation capability based on modern information technology. This paper describes how to enhance the art appreciation capability in detail, and designs and analyzes the platform to enhance college students’ art appreciation capability based on modern information technology---the “Music Corner” and the “Dance Corner”, indicating that the exchange platform built with modern information technology can promotes the college students’ art appreciation capability. Finally, through the analysis of statistical results of the questionnaire, college students are fonder of art appreciation after the establishment of platform, more inclined to the comprehensive learning of art, more brave to express their own sense of art, and fonder of artistic creation.

  12. Design and Research of Service Platform for Protection and Dissemination of Cultural Heritage Resources of The Silk Road in the Territory of China

    Science.gov (United States)

    Zhang, L.; Zhang, W.; Zeng, S. J.; Na, W.; Yang, H.; Huang, J.; Tan, X. D.; Sun, Z. J.

    2015-08-01

    The Silk Road, a major traffic route across the Eurasia continent, has been a convergence for the exchange, communication and dissemination of various cultures such as nations, materials, religions and arts for more than two thousand years. And the cultural heritage along the long and complicate route has been also attractive. In recent years, the Silk Road - the Road Network along the Chang'an-Tianshan Mountain has been listed in the Directory of World Cultural Heritage. The rare and rich cultural resources along the Silk Road, especially those in the territory of China, have attracted attentions of the world. This article describes the research ideas, methods, processes and results of the planning design on the internet-based dissemination services platform system for cultural heritage resources. First of all, it has defined the targeting for dissemination services and the research methods applied for the Silk Road heritage resources, based on scientific and objective spatial measurement and research on history and geography, to carry on the excavation of values of cultural resource for the target users. Then, with the front-end art exhibit by means of innovative IT, time and space maps of cultural heritage resources, interactive graphics display, panoramic three-dimensional virtual tour, and the Silk Road topics as the main features, a comprehensive and multi-angle cultural resources dissemination services platform is built. The research core of the platform is a demand-oriented system design on the basis of cultural resources and features as the fundamental, the value of contemporary manifestation as the foundation, and cultural dissemination and service as a starting point. This platform has achieved, temporal context generalization, interest profiles extension, online and offline adaptation, and other prominent innovations. On the basis of routes heritage resource protection and dissemination services with complex relationship between time and space, and the

  13. SenStick: Comprehensive Sensing Platform with an Ultra Tiny All-In-One Sensor Board for IoT Research

    Directory of Open Access Journals (Sweden)

    Yugo Nakamura

    2017-01-01

    Full Text Available We propose a comprehensive sensing platform called SenStick, which is composed of hardware (ultra tiny all-in-one sensor board, software (iOS, Android, and PC, and 3D case data. The platform aims to allow all the researchers to start IoT research, such as activity recognition and context estimation, easily and efficiently. The most important contribution is the hardware that we have designed. Various sensors often used for research are embedded in an ultra tiny board with the size of 50 mm (W × 10 mm (H × 5 mm (D and weight around 3 g including a battery. Concretely, the following sensors are embedded on this board: acceleration, gyro, magnetic, light, UV, temperature, humidity, and pressure. In addition, this board has BLE (Bluetooth low energy connectivity and capability of a rechargeable battery. By using 110 mAh battery, it can run more than 15 hours. The most different point from other similar boards is that our board has a large flash memory for logging all the data without a smartphone. By using SenStick, all the users can collect various data easily and focus on IoT data analytics. In this paper, we introduce SenStick platform and some case studies. Through the user study, we confirmed the usefulness of our proposed platform.

  14. Social network analysis of multi-stakeholder platforms in agricultural research for development: Opportunities and constraints for innovation and scaling.

    Science.gov (United States)

    Hermans, Frans; Sartas, Murat; van Schagen, Boudy; van Asten, Piet; Schut, Marc

    2017-01-01

    Multi-stakeholder platforms (MSPs) are seen as a promising vehicle to achieve agricultural development impacts. By increasing collaboration, exchange of knowledge and influence mediation among farmers, researchers and other stakeholders, MSPs supposedly enhance their 'capacity to innovate' and contribute to the 'scaling of innovations'. The objective of this paper is to explore the capacity to innovate and scaling potential of three MSPs in Burundi, Rwanda and the South Kivu province located in the eastern part of Democratic Republic of Congo (DRC). In order to do this, we apply Social Network Analysis and Exponential Random Graph Modelling (ERGM) to investigate the structural properties of the collaborative, knowledge exchange and influence networks of these MSPs and compared them against value propositions derived from the innovation network literature. Results demonstrate a number of mismatches between collaboration, knowledge exchange and influence networks for effective innovation and scaling processes in all three countries: NGOs and private sector are respectively over- and under-represented in the MSP networks. Linkages between local and higher levels are weak, and influential organisations (e.g., high-level government actors) are often not part of the MSP or are not actively linked to by other organisations. Organisations with a central position in the knowledge network are more sought out for collaboration. The scaling of innovations is primarily between the same type of organisations across different administrative levels, but not between different types of organisations. The results illustrate the potential of Social Network Analysis and ERGMs to identify the strengths and limitations of MSPs in terms of achieving development impacts.

  15. Social network analysis of multi-stakeholder platforms in agricultural research for development: Opportunities and constraints for innovation and scaling.

    Directory of Open Access Journals (Sweden)

    Frans Hermans

    Full Text Available Multi-stakeholder platforms (MSPs are seen as a promising vehicle to achieve agricultural development impacts. By increasing collaboration, exchange of knowledge and influence mediation among farmers, researchers and other stakeholders, MSPs supposedly enhance their 'capacity to innovate' and contribute to the 'scaling of innovations'. The objective of this paper is to explore the capacity to innovate and scaling potential of three MSPs in Burundi, Rwanda and the South Kivu province located in the eastern part of Democratic Republic of Congo (DRC. In order to do this, we apply Social Network Analysis and Exponential Random Graph Modelling (ERGM to investigate the structural properties of the collaborative, knowledge exchange and influence networks of these MSPs and compared them against value propositions derived from the innovation network literature. Results demonstrate a number of mismatches between collaboration, knowledge exchange and influence networks for effective innovation and scaling processes in all three countries: NGOs and private sector are respectively over- and under-represented in the MSP networks. Linkages between local and higher levels are weak, and influential organisations (e.g., high-level government actors are often not part of the MSP or are not actively linked to by other organisations. Organisations with a central position in the knowledge network are more sought out for collaboration. The scaling of innovations is primarily between the same type of organisations across different administrative levels, but not between different types of organisations. The results illustrate the potential of Social Network Analysis and ERGMs to identify the strengths and limitations of MSPs in terms of achieving development impacts.

  16. Motor Phenotype in Neurodegenerative Disorders: Gait and Balance Platform Study Design Protocol for the Ontario Neurodegenerative Research Initiative (ONDRI).

    Science.gov (United States)

    Montero-Odasso, Manuel; Pieruccini-Faria, Frederico; Bartha, Robert; Black, Sandra E; Finger, Elizabeth; Freedman, Morris; Greenberg, Barry; Grimes, David A; Hegele, Robert A; Hudson, Christopher; Kleinstiver, Peter W; Lang, Anthony E; Masellis, Mario; McLaughlin, Paula M; Munoz, Douglas P; Strother, Stephen; Swartz, Richard H; Symons, Sean; Tartaglia, Maria Carmela; Zinman, Lorne; Strong, Michael J; McIlroy, William

    2017-01-01

    The association of cognitive and motor impairments in Alzheimer's disease and other neurodegenerative diseases is thought to be related to damage in the common brain networks shared by cognitive and cortical motor control processes. These common brain networks play a pivotal role in selecting movements and postural synergies that meet an individual's needs. Pathology in this "highest level" of motor control produces abnormalities of gait and posture referred to as highest-level gait disorders. Impairments in cognition and mobility, including falls, are present in almost all neurodegenerative diseases, suggesting common mechanisms that still need to be unraveled. To identify motor-cognitive profiles across neurodegenerative diseases in a large cohort of patients. Cohort study that includes up to 500 participants, followed every year for three years, across five neurodegenerative disease groups: Alzheimer's disease/mild cognitive impairment, frontotemporal degeneration, vascular cognitive impairment, amyotrophic lateral sclerosis, and Parkinson's disease. Gait and balance will be assessed using accelerometers and electronic walkways, evaluated at different levels of cognitive and sensory complexity, using the dual-task paradigm. Comparison of cognitive and motor performances across neurodegenerative groups will allow the identification of motor-cognitive phenotypes through the standardized evaluation of gait and balance characteristics. As part of the Ontario Neurodegenerative Research Initiative (ONDRI), the gait and balance platform aims to identify motor-cognitive profiles across neurodegenerative diseases. Gait assessment, particularly while dual-tasking, will help dissect the cognitive and motor contribution in mobility and cognitive decline, progression to dementia syndromes, and future adverse outcomes including falls and mortality.

  17. User preferences and usability of iVitality: optimizing an innovative online research platform for home-based health monitoring

    Directory of Open Access Journals (Sweden)

    van Osch M

    2015-06-01

    Full Text Available Mara van Osch,1 AJM Rövekamp,2 Stephanie N Bergman-Agteres,1 Liselotte W Wijsman,3,4 Sharon J Ooms,5 Simon P Mooijaart,3,4,6 Joan Vermeulen71Netherlands Institute for Health Services Research, Utrecht, 2Netherlands Organization for Applied Scientific Research, 3Department of Gerontology and Geriatrics, Leiden University Medical Centre, 4Netherlands Consortium for Healthy Ageing, Leiden, 5Department of Geriatric Medicine, Radboud Alzheimer Centre, Radboud University Nijmegen Medical Centre, Nijmegen, 6Institute for Evidence-Based Medicine in Old Age, Leiden, 7Research School, CAPHRI, Maastricht University, Maastricht, the NetherlandsBackground: The iVitality online research platform has been developed to gain insight into the relationship between early risk factors (ie, poorly controlled hypertension, physical or mental inactivity and onset and possibly prevention of dementia. iVitality consists of a website, a smartphone application, and sensors that can monitor these indicators at home. Before iVitality can be implemented, it should fit the needs and preferences of users, ie, offspring of patients with dementia. This study aimed to explore users’ motivation to participate in home-based health monitoring research, to formulate requirements based on users’ preferences to optimize iVitality, and to test usability of the smartphone application of iVitality.Methods: We recruited 13 participants (aged 42–64 years, 85% female, who were offspring of patients with dementia. A user-centered methodology consisting of four iterative phases was used. Three semistructured interviews provided insight into motivation and acceptance of using iVitality (phase 1. A focus group with six participants elaborated on expectations and preferences regarding iVitality (phase 2. Findings from phase 1 and 2 were triangulated by two semistructured interviews (phase 3. Four participants assessed the usability of the smartphone application (phase 4 using a think aloud

  18. Achievement report for fiscal 1998. Research and development of advanced functional materials designing platform; 1998 nendo kokino zairyo sekkei platform no kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Stated in this paper are the reports of the working groups (WGs) for the above-named endeavor and the reports on the achievements of the universities to whom the jobs had been commissioned. WG1 carried out research and development related to the coarse-grained molecular dynamics method. WG2 dealt with mesoscale structures, which are quite larger than atoms, such the phase separated structure of polymer molecules and interfacial structures, worked for the construction of a general-purpose simulator system for reproducing/predicting their dynamic properties, and studied the properties of polymers by use of the said simulator system. WG3 worked on polymeric phenomena large in scale in terms of both space and time. Faculty of Engineering, Yamagata University, constructed a materials physical property database necessary in designing materials by simulation. Institute of Industrial Science, Tokyo University, studied the viscoelastic phase isolation at the quantitative level. Tokyo University's Faculty of Engineering-managed study teams investigated the nano-scale structures and properties of polymer materials. Faculty of Engineering, Tokyo Institute of Technology, performed research and development about the meso-scale behavior of multi-constituent polymers. (NEDO)

  19. The Melbourne East Monash General Practice Database (MAGNET: Using data from computerised medical records to create a platform for primary care and health services research

    Directory of Open Access Journals (Sweden)

    Danielle Mazza

    2016-07-01

    Full Text Available The Melbourne East MonAsh GeNeral PracticE DaTabase (MAGNET research platform was launched in 2013 to provide a unique data source for primary care and health services research in Australia.  MAGNET contains information from the computerised records of 50 participating general practices and includes data from the computerised medical records of more than 1,100,000 patients.  The data extracted is patient-level episodic information and includes a variety of fields related to patient demographics and historical clinical information, along with the characteristics of the participating general practices.  While there are limitations to the data that is currently available, the MAGNET research platform continues to investigate other avenues for improving the breadth and quality of data, with the aim of providing a more comprehensive picture of primary care in Australia

  20. The Melbourne East Monash General Practice Database (MAGNET): Using data from computerised medical records to create a platform for primary care and health services research.

    Science.gov (United States)

    Mazza, Danielle; Pearce, Christopher; Turner, Lyle Robert; De Leon-Santiago, Maria; McLeod, Adam; Ferriggi, Jason; Shearer, Marianne

    2016-07-04

    The Melbourne East MonAsh GeNeral PracticE DaTabase (MAGNET) research platform was launched in 2013 to provide a unique data source for primary care and health services research in Australia.  MAGNET contains information from the computerised records of 50 participating general practices and includes data from the computerised medical records of more than 1,100,000 patients.  The data extracted is patient-level episodic information and includes a variety of fields related to patient demographics and historical clinical information, along with the characteristics of the participating general practices.  While there are limitations to the data that is currently available, the MAGNET research platform continues to investigate other avenues for improving the breadth and quality of data, with the aim of providing a more comprehensive picture of primary care in Australia.

  1. SU-E-T-157: CARMEN: A MatLab-Based Research Platform for Monte Carlo Treatment Planning (MCTP) and Customized System for Planning Evaluation

    International Nuclear Information System (INIS)

    Baeza, J.A.; Ureba, A.; Jimenez-Ortega, E.; Barbeiro, A.R.; Plaza, A. Leal; Lagares, J.I.

    2015-01-01

    Purpose: Although there exist several radiotherapy research platforms, such as: CERR, the most widely used and referenced; SlicerRT, which allows treatment plan comparison from various sources; and MMCTP, a full MCTP system; it is still needed a full MCTP toolset that provides users complete control of calculation grids, interpolation methods and filters in order to “fairly” compare results from different TPSs, supporting verification with experimental measurements. Methods: This work presents CARMEN, a MatLab-based platform including multicore and GPGPU accelerated functions for loading RT data; designing treatment plans; and evaluating dose matrices and experimental data.CARMEN supports anatomic and functional imaging in DICOM format, as well as RTSTRUCT, RTPLAN and RTDOSE. Besides, it contains numerous tools to accomplish the MCTP process, managing egs4phant and phase space files.CARMEN planning mode assist in designing IMRT, VMAT and MERT treatments via both inverse and direct optimization. The evaluation mode contains a comprehensive toolset (e.g. 2D/3D gamma evaluation, difference matrices, profiles, DVH, etc.) to compare datasets from commercial TPS, MC simulations (i.e. 3ddose) and radiochromic film in a user-controlled manner. Results: CARMEN has been validated against commercial RTPs and well-established evaluation tools, showing coherent behavior of its multiple algorithms. Furthermore, CARMEN platform has been used to generate competitive complex treatment that has been published in comparative studies. Conclusion: A new research oriented MCTP platform with a customized validation toolset has been presented. Despite of being coded with a high-level programming language, CARMEN is agile due to the use of parallel algorithms. The wide-spread use of MatLab provides straightforward access to CARMEN’s algorithms to most researchers. Similarly, our platform can benefit from the MatLab community scientific developments as filters, registration algorithms

  2. MO-E-18C-05: Global Health Catalyst: A Novel Platform for Enhancing Access to Medical Physics Education and Research Excellence (AMPERE)

    International Nuclear Information System (INIS)

    Ngwa, W; Moreau, M; Asana, L

    2014-01-01

    Purpose: To develop a platform for catalyzing collaborative global Cancer Care Education and Research (CaRE), with a prime focus on enhancing Access to Medical Physics Education and Research Excellence (AMPERE) Methods: An analysis of over 50 global health collaborations between partners in the U.S. and low and middle income countries (LMIC) in Africa was carried out to assess the models of collaborations in Education and Research and relative success. A survey was carried out with questions including: the nature of the collaboration, how it was initiated, impact of culture and other factors, and recommendations for catalyzing/enhancing such collaborations. An online platform called Global Health Catalyst was developed for enhancing AMPERE. Results: The analysis yielded three main models for global health collaborations with survey providing key recommendations on how to enhance such collaborations. Based on this, the platform was developed, and customized to allow Medical Physicists and other Radiation oncology (RadOnc) professionals interested in participating in Global health to readily do so e.g. teach an online course module, participate in training Medical Physicists or other RadOnc health professionals in LMIC, co-mentor students, residents or postdocs, etc. The growing list of features on the platform also include: a feature to enable people to easily find each other, form teams, operate more effectively as partners from different disciplines, institutions, nations and cultural backgrounds, share tools and technologies, obtain seed funding to develop curricula and/or embark upon new areas of investigation, and participate in humanitarian outreach: remote treatment planning assistance, and participation in virtual Chart Rounds, etc. Conclusion: The developed Global Health Catalyst platform could enable any Medical Physicist or RadoOnc professional interested in global health to readily participate in the Education/training of next generation Rad

  3. SU-E-T-157: CARMEN: A MatLab-Based Research Platform for Monte Carlo Treatment Planning (MCTP) and Customized System for Planning Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Baeza, J.A.; Ureba, A.; Jimenez-Ortega, E.; Barbeiro, A.R.; Plaza, A. Leal [Universidad de Sevilla, Departamento de Fisiologia Medica y Biofisica, Seville (Spain); Lagares, J.I. [Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas (CIEMAT), Madrid (Spain)

    2015-06-15

    Purpose: Although there exist several radiotherapy research platforms, such as: CERR, the most widely used and referenced; SlicerRT, which allows treatment plan comparison from various sources; and MMCTP, a full MCTP system; it is still needed a full MCTP toolset that provides users complete control of calculation grids, interpolation methods and filters in order to “fairly” compare results from different TPSs, supporting verification with experimental measurements. Methods: This work presents CARMEN, a MatLab-based platform including multicore and GPGPU accelerated functions for loading RT data; designing treatment plans; and evaluating dose matrices and experimental data.CARMEN supports anatomic and functional imaging in DICOM format, as well as RTSTRUCT, RTPLAN and RTDOSE. Besides, it contains numerous tools to accomplish the MCTP process, managing egs4phant and phase space files.CARMEN planning mode assist in designing IMRT, VMAT and MERT treatments via both inverse and direct optimization. The evaluation mode contains a comprehensive toolset (e.g. 2D/3D gamma evaluation, difference matrices, profiles, DVH, etc.) to compare datasets from commercial TPS, MC simulations (i.e. 3ddose) and radiochromic film in a user-controlled manner. Results: CARMEN has been validated against commercial RTPs and well-established evaluation tools, showing coherent behavior of its multiple algorithms. Furthermore, CARMEN platform has been used to generate competitive complex treatment that has been published in comparative studies. Conclusion: A new research oriented MCTP platform with a customized validation toolset has been presented. Despite of being coded with a high-level programming language, CARMEN is agile due to the use of parallel algorithms. The wide-spread use of MatLab provides straightforward access to CARMEN’s algorithms to most researchers. Similarly, our platform can benefit from the MatLab community scientific developments as filters, registration algorithms

  4. MO-E-18C-05: Global Health Catalyst: A Novel Platform for Enhancing Access to Medical Physics Education and Research Excellence (AMPERE)

    Energy Technology Data Exchange (ETDEWEB)

    Ngwa, W [Harvard Medical School, Boston, MA (United States); University of Massachusetts, Lowell, Massachusetts (United States); Moreau, M [University of Massachusetts, Lowell, Massachusetts (United States); Asana, L [African Renaissance Ambassador Corp, Orlando, FL (United States)

    2014-06-15

    Purpose: To develop a platform for catalyzing collaborative global Cancer Care Education and Research (CaRE), with a prime focus on enhancing Access to Medical Physics Education and Research Excellence (AMPERE) Methods: An analysis of over 50 global health collaborations between partners in the U.S. and low and middle income countries (LMIC) in Africa was carried out to assess the models of collaborations in Education and Research and relative success. A survey was carried out with questions including: the nature of the collaboration, how it was initiated, impact of culture and other factors, and recommendations for catalyzing/enhancing such collaborations. An online platform called Global Health Catalyst was developed for enhancing AMPERE. Results: The analysis yielded three main models for global health collaborations with survey providing key recommendations on how to enhance such collaborations. Based on this, the platform was developed, and customized to allow Medical Physicists and other Radiation oncology (RadOnc) professionals interested in participating in Global health to readily do so e.g. teach an online course module, participate in training Medical Physicists or other RadOnc health professionals in LMIC, co-mentor students, residents or postdocs, etc. The growing list of features on the platform also include: a feature to enable people to easily find each other, form teams, operate more effectively as partners from different disciplines, institutions, nations and cultural backgrounds, share tools and technologies, obtain seed funding to develop curricula and/or embark upon new areas of investigation, and participate in humanitarian outreach: remote treatment planning assistance, and participation in virtual Chart Rounds, etc. Conclusion: The developed Global Health Catalyst platform could enable any Medical Physicist or RadoOnc professional interested in global health to readily participate in the Education/training of next generation Rad

  5. Platform Performance and Challenges - using Platforms in Lego Company

    DEFF Research Database (Denmark)

    Munk, Lone; Mortensen, Niels Henrik

    2009-01-01

    needs focus on the incentive of using the platform. This problem lacks attention in literature, as well as industry, where assessment criteria do not cover this aspect. Therefore, we recommend including user incentive in platform assessment criteria to these challenges. Concrete solution elements...... ensuring user incentive in platforms is an object for future research...

  6. Fiscal 1999 achievement report on interuniversity coordination type research and development of industrial technology. Research and development of highly functional material designing platform; 1999 nendo kokino zairyo sekkei platform no kenkyu kaihatsu seika hokokusho. Energy shiyo gorika gijutsu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    For the purpose of enabling prediction of structures and properties of polymeric materials by computer-assisted experiments, studies were conducted for putting new simulation technologies to practical application. With the coarse-graining molecular dynamic method working group, a coarse-graining molecular dynamic engine high in generality and augmentability was developed so that an optimum coarse-graining model might be chosen and constructed to achieve any given purpose, and its installation was almost completed. The dynamic mean field method working group fabricated a new general-purpose simulator with its interface simplified and function improved. A simulation technique was also developed, which would be incorporated into the general-purpose simulator. The dispersed structure simulation working group developed a group of class libraries for use in continuum simulation. The platform working group, making use of Java excellent in general-purpose feature, worked out a function verification platform to run on Windows95/98/NT. (NEDO)

  7. Joint Research Centre Copernicus Climate Change Service (C3S) Fitness-for-Purpose (F4P) Platform

    Science.gov (United States)

    Gobron, N.; Adams, J. S.; Cappucci, F.; Lanconelli, C.; Mota, B.; Melin, F.

    2016-08-01

    This paper presents the concept and first results of the Copernicus Climate Change Service Fitness-for-Purpose (C3S F4P) project. The main goal aims at evaluating the efficiency and overall performance of the service, mainly with regard to users information needs and high level requirements. This project will also assess the fitness- for-purpose of the C3S with a specific emphasis on the needs of European Union (EU) Policies and translate these recommendations into programmatic and technical requirements. The C3S Climate Data Records (CDS) include various Essential Climate Variables (ECVs) that are derived from space sensors, including from Copernicus Sentinels sensors. One module of the F4P platform focuses on the benchmarking of data sets and algorithms, in addition to radiative transfer models used towards understanding potential discrepancies between CDS records. Methods and preliminary results of the benchmark platform are presented in this contribution.

  8. Research on market power and market structure: A direct measure of market power of internet platform enterprises

    Directory of Open Access Journals (Sweden)

    Baowen Sun

    2017-09-01

    Full Text Available Purpose – This paper aims to clear whether the monopoly structure of the internet industry has produced market power and discussed the welfare change of the internet industry monopoly. Design/methodology/approach – By using new empirical industrial organization methods and taking the e-commerce market as an example, the authors measured market power and economies of scale of the internet platform companies. Findings – Internet platform enterprises have formed scale economy, but it has not had market power, and the industry still maintains high levels of competition; also, the emergence of large enterprises may increase the welfare of consumers. Originality/value – The conclusion of this paper clarified actual competition status of internet industry and provided a new foothold for regulation and ideas for the traditional industry to crack the Marshall Conflict.

  9. KubeNow: an On-Demand Cloud-Agnostic Platform for Microservices-Based Research Environments

    OpenAIRE

    Capuccini, Marco; Larsson, Anders; Carone, Matteo; Novella, Jon Ander; Sadawi, Noureddin; Gao, Jianliang; Toor, Salman; Spjuth, Ola

    2018-01-01

    Microservices platforms, such as Kubernetes, have received a great deal of attention lately as they offer elastic and resilient orchestration for services implemented as portable, light-weight, software containers. While current solutions for cloud-based Kubernetes deployments are mainly focusing on maintaining long-running infrastructure, aimed to sustain highly-available services, the scientific community is embracing software containers for more demanding data analysis. To this extent, the...

  10. An overview on development and application of an experimental platform for quantitative cardiac imaging research in rabbit models of myocardial infarction.

    Science.gov (United States)

    Feng, Yuanbo; Bogaert, Jan; Oyen, Raymond; Ni, Yicheng

    2014-10-01

    To exploit the advantages of using rabbits for cardiac imaging research and to tackle the technical obstacles, efforts have been made under the framework of a doctoral research program. In this overview article, by cross-referencing the current literature, we summarize how we have developed a preclinical cardiac research platform based on modified models of reperfused myocardial infarction (MI) in rabbits; how the in vivo manifestations of cardiac imaging could be closely matched with those ex vivo macro- and microscopic findings; how these imaging outcomes could be quantitatively analyzed, validated and demonstrated; and how we could apply this cardiac imaging platform to provide possible solutions to certain lingering diagnostic and therapeutic problems in experimental cardiology. In particular, tissue components in acute cardiac ischemia have been stratified and characterized, post-infarct lipomatous metaplasia (LM) as a common but hardly illuminated clinical pathology has been identified in rabbit models, and a necrosis avid tracer as well as an anti-ischemic drug have been successfully assessed for their potential utilities in clinical cardiology. These outcomes may interest the researchers in the related fields and help strengthen translational research in cardiovascular diseases.

  11. Business analysis for a sustainable, multi-stakeholder ecosystem for leveraging the Electronic Health Records for Clinical Research (EHR4CR) platform in Europe.

    Science.gov (United States)

    Dupont, Danielle; Beresniak, Ariel; Sundgren, Mats; Schmidt, Andreas; Ainsworth, John; Coorevits, Pascal; Kalra, Dipak; Dewispelaere, Marc; De Moor, Georges

    2017-01-01

    The Electronic Health Records for Clinical Research (EHR4CR) technological platform has been developed to enable the trustworthy reuse of hospital electronic health records data for clinical research. The EHR4CR platform can enhance and speed up clinical research scenarios: protocol feasibility assessment, patient identification for recruitment in clinical trials, and clinical data exchange, including for reporting serious adverse events. Our objective was to seed a multi-stakeholder ecosystem to enable the scalable exploitation of the EHR4CR platform in Europe, and to assess its economic sustainability. Market analyses were conducted by a multidisciplinary task force to define an EHR4CR emerging ecosystem and multi-stakeholder value chain. This involved mapping stakeholder groups and defining their unmet needs, incentives, potential barriers for adopting innovative solutions, roles and interdependencies. A comprehensive business model, value propositions, and sustainability strategies were developed accordingly. Using simulation modelling (including Monte Carlo simulations) and a 5-year horizon, the potential financial outcomes of the business model were forecasted from the perspective of an EHR4CR service provider. A business ecosystem was defined to leverage the EHR4CR multi-stakeholder value chain. Value propositions were developed describing the expected benefits of EHR4CR solutions for all stakeholders. From an EHR4CR service provider's viewpoint, the business model simulation estimated that a profitability ratio of up to 1.8 could be achieved at year 1, with potential for growth in subsequent years depending on projected market uptake. By enhancing and speeding up existing processes, EHR4CR solutions promise to transform the clinical research landscape. The ecosystem defined provides the organisational framework for optimising the value and benefits for all stakeholders involved, in a sustainable manner. Our study suggests that the exploitation of EHR4CR

  12. Identification of platform levels

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik

    2005-01-01

    reduction, ability to launch a wider product portfolio without increasing resources and reduction of complexity within the whole company. To support the multiple product development process, platform based product development has in many companies such as Philips, VW, Ford etc. proven to be a very effective...... product development in one step and therefore the objective of this paper is to identify levels of platform based product development. The structure of this paper is as follows. First the applied terminology for platforms will be briefly explained and then characteristics between single and multi product...... development will be examined. Based on the identification of the above characteristics five platform levels are described. The research presented in this paper is a result of MSc, Ph.D projects at the Technical University of Denmark and consultancy projects within the organisation of Institute of Product...

  13. Research and Deployment a Hospital Open Software Platform for e-Health on the Grid System at VAST/IAMI

    Science.gov (United States)

    van Tuyet, Dao; Tuan, Ngo Anh; van Lang, Tran

    Grid computing has been an increasing topic in recent years. It attracts the attention of many scientists from many fields. As a result, many Grid systems have been built for serving people's demands. At present, many tools for developing the Grid systems such as Globus, gLite, Unicore still developed incessantly. Especially, gLite - the Grid Middleware - was developed by the Europe Community scientific in recent years. Constant growth of Grid technology opened the way for new opportunities in term of information and data exchange in a secure and collaborative context. These new opportunities can be exploited to offer physicians new telemedicine services in order to improve their collaborative capacities. Our platform gives physicians an easy method to use telemedicine environment to manage and share patient's information (such as electronic medical record, images formatted DICOM) between remote locations. This paper presents the Grid Infrastructure based on gLite; some main components of gLite; the challenge scenario in which new applications can be developed to improve collaborative work between scientists; the process of deploying Hospital Open software Platform for E-health (HOPE) on the Grid.

  14. SciLite: a platform for displaying text-mined annotations as a means to link research articles with biological data

    Science.gov (United States)

    Talo, Francesco; Ide-Smith, Michele; Gobeill, Julien; Carter, Jacob; Batista-Navarro, Riza; Ananiadou, Sophia; Ruch, Patrick; McEntyre, Johanna

    2017-01-01

    The tremendous growth in biological data has resulted in an increase in the number of research papers being published. This presents a great challenge for scientists in searching and assimilating facts described in those papers. Particularly, biological databases depend on curators to add highly precise and useful information that are usually extracted by reading research articles. Therefore, there is an urgent need to find ways to improve linking literature to the underlying data, thereby minimising the effort in browsing content and identifying key biological concepts.   As part of the development of Europe PMC, we have developed a new platform, SciLite, which integrates text-mined annotations from different sources and overlays those outputs on research articles. The aim is to aid researchers and curators using Europe PMC in finding key concepts more easily and provide links to related resources or tools, bridging the gap between literature and biological data. PMID:28948232

  15. [Establishment pharmacological research platform for "Concurrent treatment of the brain and heart" and its application on dissecting mechanism of Danhong injection].

    Science.gov (United States)

    Zhao, Xiao-Ping; Yu, Yun-Ru; Li, Xue; Shao, Qing; Wang, Yi-Min; Zhao, Tao; Zhao, Chao; Zhao, Bu-Chang; Wang, Yue-Fei; Wang, Yi

    2017-12-01

    The Concurrent treatment of the brain and heart (CTBH) theory is proposed based on traditional Chinese medical theory and clinical practice. In this study, a framework for the pharmacological research platform was established to investigate the principles of concurrent treatment of the brain and heart. The platform for CTBH includes several key techniques for network modeling, discovery of active substances, dissecting mechanism of action and investigation of pharmacokinetic property of TCM. Taking network modeling of CTBH as an example, using database search, literature mining, network construction and module analysis, the that network modules closely associated with the pathological progress of cardiovascular and cerebrovascular diseases were identified, while further functional enrichment analysis of these modules indicated that the key biological processes included oxidative stress, metabolism and inflammation. GSK3B, NOTCH1, CDK4 were identified as key nodes in these network modules. The above-mentioned platform was applied to construct component-biomolecules network of Danhong injection for the identification of common targets and pathways. Among them, GSK3B had the highest correlation with the composition of Danhong injection in the network, and the biological function of whose cluster was related to cell oxidative stress. Based upon results of network analysis, validation experiments suggested that Danhong injection significantly improved the survival rate of oxidative injured myocardial cells and nerve cells, and the protective effect was related to the increase of phosphorylated GSK3β protein expression. Moreover, extracts of Salviae Miltiorrhizae Radix et Rhizoma and Carthami Flos exerted the synergisticcytoprotective effect. The results indicated that the mechanism of treatment of cardiovascular and cerebrovascular diseases of Danhong injection could be studied through network modeling and other methods. In summary, the proposed pharmacological

  16. Platform computing

    CERN Multimedia

    2002-01-01

    "Platform Computing releases first grid-enabled workload management solution for IBM eServer Intel and UNIX high performance computing clusters. This Out-of-the-box solution maximizes the performance and capability of applications on IBM HPC clusters" (1/2 page) .

  17. Temperature profile data from XBT casts in a World-wide distribution from NOAA Ship RESEARCHER and other platforms from 1982-05-24 to 1996-03-21 (NODC Accession 9600116)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using XBT casts in a World-wide distribution from NOAA Ship RESEARCHER and other platforms from 24 May 1982 to 21 March 1996....

  18. Physical and chemical data collected using bottle and BTs casts in the TOGA Area of Atlantic Ocean from NOAA Ship RESEARCHER and other platforms from 1974-06-25 to 1974-08-16 (NODC Accession 7700649)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data was collected from June 25, 1974 to August 16, 1974 using METEOR and other platforms as part of GARP (Global Atmospheric Research Program) Atlantic Tropical...

  19. WATER TEMPERATURE and other data from NOAA Ship RESEARCHER, NOAA Ship MILLER FREEMAN and other platforms in the Gulf of Mexico, NW Atlantic and NE Pacific from 1987-01-08 to 1987-07-01 (NODC Accession 8700254)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using XBT and BT casts from NOAA Ship RESEARCHER and other platforms in the Gulf of Mexico and Northwest Atlantic Ocean from...

  20. Temperature profile data collected using BT and XBT casts from NOAA Ship RESEARCHER and other platforms in the Bering Sea and other Sea areas from 1987-02-25 to 1987-07-27 (NODC Accession 8700280)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using XBT and BT casts from NOAA Ship RESEARCHER and other platforms in the Bering Sea and other Sea areas from 25 February...

  1. Temperature profile data collected using XBT and BT casts in the TOGA Area of Pacific Ocean from NOAA Ship RESEARCHER and other platforms from 1979-02-28 to 1991-07-27 (NODC Accession 9300170)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using XBT and BT casts from NOAA Ship RESEARCHER and other platforms in the TOGA Area of Pacific Ocean from 28 February 1979...

  2. Temperature profile and other data from CTD Casts in the Gulf of Mexico and TOGA Area - Pacific Ocean from NOAA Ship RESEARCHER and other platforms from 1982-03-26 to 1983-11-26 (NODC Accession 8500267)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile and other data were collected using CTD casts from NOAA Ship RESEARCHER and other platforms in the Gulf of Mexico and TOGA Area - Pacific Ocean...

  3. Temperature profile data collected using XBT and BT casts in a World-wide distribution from NOAA Ship RESEARCHER and other platforms from 1970-09-30 to 1979-08-05 (NODC Accession 8300089)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using XBT and BT casts from NOAA Ship RESEARCHER and other platforms in a World-wide distribution from 30 September 1970 to...

  4. Physical and chemical data collected using bottle casts in a World-wide distribution from NOAA Ship RESEARCHER and other platforms from 1911-11-11 to 1990-03-18 (NODC Accession 9600072)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Physical and chemical data were collected using bottle casts in a World-wide distribution from NOAA Ship RESEARCHER and other platforms from 11 November 1911 to 18...

  5. Temperature profile data collected using XBT and BT casts in a world-wide distribution from NOAA Ship RESEARCHER and other platforms from 1982-08-18 to 1982-12-21 (NODC Accession 8300007)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using XBT and BT casts from NOAA Ship RESEARCHER and other platforms in a world-wide distribution from 18 August 1982 to 21...

  6. Zooplankton data collected from zooplankton net casts from RESEARCHER I and other platforms in TOGA Area of Pacific Ocean; 16 March 1968 to 02 July 1970 (NODC Accession 9500141)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Zooplankton species identities and other data were collected using zooplankton casts in the TOGA Area of Pacific Ocean from RESEARCHER I and other platforms. Data...

  7. Temperature profile and other data collected using BT, XBT, and other instruments from NOAA Ship RESEARCHER and other platforms in the Gulf of Mexico from 1982-08-18 to 1985-04-06 (NODC Accession 8900211)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile and other data were collected using XBT, BT, and other instruments from NOAA Ship RESEARCHER and other platforms in the Gulf of Mexico from 18...

  8. Temperature profile and other data collected using CTD casts in the TOGA Area - Pacific Ocean from NOAA Ship RESEARCHER and other platforms from 1984-11-13 to 1986-12-01 (NODC Accession 8700194)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile and other data were collected using CTD casts from NOAA Ship RESEARCHER and other platforms in the TOGA Area - Pacific Ocean from 13 November...

  9. Envri Cluster - a Community-Driven Platform of European Environmental Researcher Infrastructures for Providing Common E-Solutions for Earth Science

    Science.gov (United States)

    Asmi, A.; Sorvari, S.; Kutsch, W. L.; Laj, P.

    2017-12-01

    European long-term environmental research infrastructures (often referred as ESFRI RIs) are the core facilities for providing services for scientists in their quest for understanding and predicting the complex Earth system and its functioning that requires long-term efforts to identify environmental changes (trends, thresholds and resilience, interactions and feedbacks). Many of the research infrastructures originally have been developed to respond to the needs of their specific research communities, however, it is clear that strong collaboration among research infrastructures is needed to serve the trans-boundary research requires exploring scientific questions at the intersection of different scientific fields, conducting joint research projects and developing concepts, devices, and methods that can be used to integrate knowledge. European Environmental research infrastructures have already been successfully worked together for many years and have established a cluster - ENVRI cluster - for their collaborative work. ENVRI cluster act as a collaborative platform where the RIs can jointly agree on the common solutions for their operations, draft strategies and policies and share best practices and knowledge. Supporting project for the ENVRI cluster, ENVRIplus project, brings together 21 European research infrastructures and infrastructure networks to work on joint technical solutions, data interoperability, access management, training, strategies and dissemination efforts. ENVRI cluster act as one stop shop for multidisciplinary RI users, other collaborative initiatives, projects and programmes and coordinates and implement jointly agreed RI strategies.

  10. Life Science Research in Outer Space: New Platform Technologies for Low-Cost, Autonomous Small Satellite Missions

    Science.gov (United States)

    Ricco, Antonio J.; Parra, Macarena P.; Niesel, David; McGinnis, Michael; Ehrenfreund, Pascale; Nicholson, Wayne; Mancinelli, Rocco; Piccini, Matthew E.; Beasley, Christopher C.; Timucin, Linda R.; hide

    2009-01-01

    We develop integrated instruments and platforms suitable for economical, frequent space access for autonomous life science experiments and processes in outer space. The technologies represented by three of our recent free-flyer small-satellite missions are the basis of a rapidly growing toolbox of miniaturized biologically/biochemically-oriented instrumentation now enabling a new generation of in-situ space experiments. Autonomous small satellites ( 1 50 kg) are less expensive to develop and build than fullsize spacecraft and not subject to the comparatively high costs and scheduling challenges of human-tended experimentation on the International Space Station, Space Shuttle, and comparable platforms. A growing number of commercial, government, military, and civilian space launches now carry small secondary science payloads at far lower cost than dedicated missions; the number of opportunities is particularly large for so-called cube-sat and multicube satellites in the 1 10 kg range. The recent explosion in nano-, micro-, and miniature technologies, spanning fields from telecommunications to materials to bio/chemical analysis, enables development of remarkably capable autonomous miniaturized instruments to accomplish remote biological experimentation. High-throughput drug discovery, point-of-care medical diagnostics, and genetic analysis are applications driving rapid progress in autonomous bioanalytical technology. Three of our recent missions exemplify the development of miniaturized analytical payload instrumentation: GeneSat-1 (launched: December 2006), PharmaSat (launched: May 2009), and O/OREOS (organism/organics exposure to orbital stresses; scheduled launch: May 2010). We will highlight the overall architecture and integration of fluidic, optical, sensor, thermal, and electronic technologies and subsystems to support and monitor the growth of microorganisms in culture in these small autonomous space satellites, including real-time tracking of their culture

  11. [Orange Platform].

    Science.gov (United States)

    Toba, Kenji

    2017-07-01

    The Organized Registration for the Assessment of dementia on Nationwide General consortium toward Effective treatment in Japan (ORANGE platform) is a recently established nationwide clinical registry for dementia. This platform consists of multiple registries of patients with dementia stratified by the following clinical stages: preclinical, mild cognitive impairment, early-stage, and advanced-stage dementia. Patients will be examined in a super-longitudinal fashion, and their lifestyle, social background, genetic risk factors, and required care process will be assessed. This project is also notable because the care registry includes information on the successful, comprehensive management of patients with dementia. Therefore, this multicenter prospective cohort study will contribute participants to all clinical trials for Alzheimer's disease as well as improve the understanding of individuals with dementia.

  12. Health Care Transformation Through Collaboration on Open-Source Informatics Projects: Integrating a Medical Applications Platform, Research Data Repository, and Patient Summarization

    Science.gov (United States)

    McCoy, Allison B; Wright, Adam; Wattanasin, Nich; Sittig, Dean F; Murphy, Shawn N

    2013-01-01

    Background The Strategic Health IT Advanced Research Projects (SHARP) program seeks to conquer well-understood challenges in medical informatics through breakthrough research. Two SHARP centers have found alignment in their methodological needs: (1) members of the National Center for Cognitive Informatics and Decision-making (NCCD) have developed knowledge bases to support problem-oriented summarizations of patient data, and (2) Substitutable Medical Apps, Reusable Technologies (SMART), which is a platform for reusable medical apps that can run on participating platforms connected to various electronic health records (EHR). Combining the work of these two centers will ensure wide dissemination of new methods for synthesized views of patient data. Informatics for Integrating Biology and the Bedside (i2b2) is an NIH-funded clinical research data repository platform in use at over 100 sites worldwide. By also working with a co-occurring initiative to SMART-enabling i2b2, we can confidently write one app that can be used extremely broadly. Objective Our goal was to facilitate development of intuitive, problem-oriented views of the patient record using NCCD knowledge bases that would run in any EHR. To do this, we developed a collaboration between the two SHARPs and an NIH center, i2b2. Methods First, we implemented collaborative tools to connect researchers at three institutions. Next, we developed a patient summarization app using the SMART platform and a previously validated NCCD problem-medication linkage knowledge base derived from the National Drug File-Reference Terminology (NDF-RT). Finally, to SMART-enable i2b2, we implemented two new Web service “cells” that expose the SMART application programming interface (API), and we made changes to the Web interface of i2b2 to host a “carousel” of SMART apps. Results We deployed our SMART-based, NDF-RT-derived patient summarization app in this SMART-i2b2 container. It displays a problem-oriented view of

  13. Health care transformation through collaboration on open-source informatics projects: integrating a medical applications platform, research data repository, and patient summarization.

    Science.gov (United States)

    Klann, Jeffrey G; McCoy, Allison B; Wright, Adam; Wattanasin, Nich; Sittig, Dean F; Murphy, Shawn N

    2013-05-30

    The Strategic Health IT Advanced Research Projects (SHARP) program seeks to conquer well-understood challenges in medical informatics through breakthrough research. Two SHARP centers have found alignment in their methodological needs: (1) members of the National Center for Cognitive Informatics and Decision-making (NCCD) have developed knowledge bases to support problem-oriented summarizations of patient data, and (2) Substitutable Medical Apps, Reusable Technologies (SMART), which is a platform for reusable medical apps that can run on participating platforms connected to various electronic health records (EHR). Combining the work of these two centers will ensure wide dissemination of new methods for synthesized views of patient data. Informatics for Integrating Biology and the Bedside (i2b2) is an NIH-funded clinical research data repository platform in use at over 100 sites worldwide. By also working with a co-occurring initiative to SMART-enabling i2b2, we can confidently write one app that can be used extremely broadly. Our goal was to facilitate development of intuitive, problem-oriented views of the patient record using NCCD knowledge bases that would run in any EHR. To do this, we developed a collaboration between the two SHARPs and an NIH center, i2b2. First, we implemented collaborative tools to connect researchers at three institutions. Next, we developed a patient summarization app using the SMART platform and a previously validated NCCD problem-medication linkage knowledge base derived from the National Drug File-Reference Terminology (NDF-RT). Finally, to SMART-enable i2b2, we implemented two new Web service "cells" that expose the SMART application programming interface (API), and we made changes to the Web interface of i2b2 to host a "carousel" of SMART apps. We deployed our SMART-based, NDF-RT-derived patient summarization app in this SMART-i2b2 container. It displays a problem-oriented view of medications and presents a line-graph display of

  14. The disruptive impact of digitalization on the automotive ecosystem: a research agenda on business models, platforms and consumer issues

    OpenAIRE

    Athanasopoulou, A.; Bouwman, W.A.G.A.; Nikayin, F.A.; de Reuver, G.A.

    2016-01-01

    Digital technologies are transforming the automotive industry, and disrupting traditional business models based on ownership of cars. With the emergence of connected cars, mobility services and servitization, questions arise on how these enabling technologies affect the ecosystem. In this paper, we propose a research agenda for the digitalized automotive ecosystem. In this research agenda we raise research questions on the impacts of digitalization on business models (i.e. how to move from tr...

  15. The Jules Horowitz nuclear complex a plat-form for research and development on nuclear fuel and materials for the 21st century

    International Nuclear Information System (INIS)

    Ballagny, A.; Bouilloux, Y.; Chantoin, P.; Iracane, D.

    2001-01-01

    The CEA intends to build a material test reactor at Cadarache (South of France). This reactor would be the central piece of a wider complex which would include experimental fuel fabrication, destructive and non destructive examinations, in-reactor on line measurement advanced methods and modelling. For 50 years this platform would provide the necessary knowledge to the nuclear industry, the safety authority and to the national decision makers. This material test reactor called Jules Horowitz reactor (JHR) could be a key facility for industry and the central component of the European research area on nuclear fission from 2010. In this paper an overview of the research complex is given and a first approach of the development effort undertaken to meet the requirements in term of : ''time to result, experimental cost, experiment quality and international co-operation. Finally are given several ways of technical development undertaken to meet the above requirements. (orig.)

  16. Disentangling Competition Among Platform Driven Strategic Groups

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric

    2015-01-01

    In platform-driven markets, competitive advantage is derived from superior platform design and configurations. For this reason, platform owners strive to create unique and inimitable platform configurals to maintain and extend their competitiveness within network economies. To disentangle firm...... competition within platform-driven markets, we opted for the UK mobile payment market as our empirical setting. By embracing the theoretical lens of strategic groups and digital platforms, this study supplements prior research by deriving a taxonomy of platform-driven strategic groups that is grounded...

  17. The Creative Platform

    DEFF Research Database (Denmark)

    Byrge, Christian; Hansen, Søren

    whether you consider thirdgrade teaching, human-resource development, or radical new thinking in product development in a company. The Creative Platform was developed at Aalborg University through a series of research-and-development activities in collaboration with educational institutions and private...

  18. CERN Neutrino Platform Hardware

    CERN Document Server

    Nelson, Kevin

    2017-01-01

    My summer research was broadly in CERN's neutrino platform hardware efforts. This project had two main components: detector assembly and data analysis work for ICARUS. Specifically, I worked on assembly for the ProtoDUNE project and monitored the safety of ICARUS as it was transported to Fermilab by analyzing the accelerometer data from its move.

  19. Psychiatric research platform within SAIL - Linkage of prospectively ascertained phenotypically rich and genetic data to routinely collected anonymised records.

    Directory of Open Access Journals (Sweden)

    Joanna McGregor

    2017-04-01

    To advance mental health research by developing our understanding of the causes, course and outcomes of mental illness that may lead to the development of better diagnostic classification, predictive, preventative strategies and therapeutic approaches.

  20. Flexible experimental FPGA based platform

    DEFF Research Database (Denmark)

    Andersen, Karsten Holm; Nymand, Morten

    2016-01-01

    This paper presents an experimental flexible Field Programmable Gate Array (FPGA) based platform for testing and verifying digital controlled dc-dc converters. The platform supports different types of control strategies, dc-dc converter topologies and switching frequencies. The controller platform...... interface supporting configuration and reading of setup parameters, controller status and the acquisition memory in a simple way. The FPGA based platform, provides an easy way within education or research to use different digital control strategies and different converter topologies controlled by an FPGA...

  1. Evaluation of Variable Refrigerant Flow Systems Performance on Oak Ridge National Laboratory s Flexible Research Platform: Part 1 Cooling Season Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Im, Piljae [ORNL; Malhotra, Mini [ORNL; Munk, Jeffrey D [ORNL

    2016-08-01

    This report provides second-year cooling season test results for the multi-year project titled “Evaluation of Variable Refrigeration Flow (VRF) System on Oak Ridge National Laboratory (ORNL)’s Flexible Research Platform (FRP).” The purpose of the second-year project was to (1) evaluate the full- and partload performance of VRF systems compared with an existing baseline heating, ventilation, and airconditioning (HVAC) system, which is a conventional rooftop unit (RTU) variable-air-volume (VAV) system with electric resistance heating and (2) use hourly building energy simulation to evaluate the energy savings potential of using VRF systems in major US cities. The second-year project performance period was from July 2015 through June 2016.

  2. Comparing Amazon's Mechanical Turk Platform to Conventional Data Collection Methods in the Health and Medical Research Literature.

    Science.gov (United States)

    Mortensen, Karoline; Hughes, Taylor L

    2018-04-01

    The goal of this article is to conduct an assessment of the peer-reviewed primary literature with study objectives to analyze Amazon.com 's Mechanical Turk (MTurk) as a research tool in a health services research and medical context. Searches of Google Scholar and PubMed databases were conducted in February 2017. We screened article titles and abstracts to identify relevant articles that compare data from MTurk samples in a health and medical context to another sample, expert opinion, or other gold standard. Full-text manuscript reviews were conducted for the 35 articles that met the study criteria. The vast majority of the studies supported the use of MTurk for a variety of academic purposes. The literature overwhelmingly concludes that MTurk is an efficient, reliable, cost-effective tool for generating sample responses that are largely comparable to those collected via more conventional means. Caveats include survey responses may not be generalizable to the US population.

  3. AAS WorldWide Telescope: A Seamless, Cross-platform Data Visualization Engine for Astronomy Research, Education, and Democratizing Data

    Science.gov (United States)

    Rosenfield, Philip; Fay, Jonathan; Gilchrist, Ronald K.; Cui, Chenzhou; Weigel, A. David; Robitaille, Thomas; Otor, Oderah Justin; Goodman, Alyssa

    2018-05-01

    The American Astronomical Society’s WorldWide Telescope (WWT) project enables terabytes of astronomical images, data, and stories to be viewed and shared among researchers, exhibited in science museums, projected into full-dome immersive planetariums and virtual reality headsets, and taught in classrooms, from middle school to college. We review the WWT ecosystem, how WWT has been used in the astronomical community, and comment on future directions.

  4. ATGC: a database of orthologous genes from closely related prokaryotic genomes and a research platform for microevolution of prokaryotes

    Energy Technology Data Exchange (ETDEWEB)

    Novichkov, Pavel S.; Ratnere, Igor; Wolf, Yuri I.; Koonin, Eugene V.; Dubchak, Inna

    2009-07-23

    The database of Alignable Tight Genomic Clusters (ATGCs) consists of closely related genomes of archaea and bacteria, and is a resource for research into prokaryotic microevolution. Construction of a data set with appropriate characteristics is a major hurdle for this type of studies. With the current rate of genome sequencing, it is difficult to follow the progress of the field and to determine which of the available genome sets meet the requirements of a given research project, in particular, with respect to the minimum and maximum levels of similarity between the included genomes. Additionally, extraction of specific content, such as genomic alignments or families of orthologs, from a selected set of genomes is a complicated and time-consuming process. The database addresses these problems by providing an intuitive and efficient web interface to browse precomputed ATGCs, select appropriate ones and access ATGC-derived data such as multiple alignments of orthologous proteins, matrices of pairwise intergenomic distances based on genome-wide analysis of synonymous and nonsynonymous substitution rates and others. The ATGC database will be regularly updated following new releases of the NCBI RefSeq. The database is hosted by the Genomics Division at Lawrence Berkeley National laboratory and is publicly available at http://atgc.lbl.gov.

  5. Evaluation of Variable Refrigerant Flow Systems Performance and the Enhanced Control Algorithm on Oak Ridge National Laboratory s Flexible Research Platform

    Energy Technology Data Exchange (ETDEWEB)

    Im, Piljae [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Munk, Jeffrey D [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Gehl, Anthony C [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-06-01

    A research project “Evaluation of Variable Refrigerant Flow (VRF) Systems Performance and the Enhanced Control Algorithm on Oak Ridge National Laboratory’s (ORNL’s) Flexible Research Platform” was performed to (1) install and validate the performance of Samsung VRF systems compared with the baseline rooftop unit (RTU) variable-air-volume (VAV) system and (2) evaluate the enhanced control algorithm for the VRF system on the two-story flexible research platform (FRP) in Oak Ridge, Tennessee. Based on the VRF system designed by Samsung and ORNL, the system was installed from February 18 through April 15, 2014. The final commissioning and system optimization were completed on June 2, 2014, and the initial test for system operation was started the following day, June 3, 2014. In addition, the enhanced control algorithm was implemented and updated on June 18. After a series of additional commissioning actions, the energy performance data from the RTU and the VRF system were monitored from July 7, 2014, through February 28, 2015. Data monitoring and analysis were performed for the cooling season and heating season separately, and the calibrated simulation model was developed and used to estimate the energy performance of the RTU and VRF systems. This final report includes discussion of the design and installation of the VRF system, the data monitoring and analysis plan, the cooling season and heating season data analysis, and the building energy modeling study

  6. Improving nutrition surveillance and public health research in Central and Eastern Europe/Balkan Countries using the Balkan Food Platform and dietary tools.

    Science.gov (United States)

    Gurinović, Mirjana; Milešević, Jelena; Novaković, Romana; Kadvan, Agnes; Djekić-Ivanković, Marija; Šatalić, Zvonimir; Korošec, Mojca; Spiroski, Igor; Ranić, Marija; Dupouy, Eleonora; Oshaug, Arne; Finglas, Paul; Glibetić, Maria

    2016-02-15

    The objective of this paper is to share experience and provide updated information on Capacity Development in the Central and Eastern Europe/Balkan Countries (CEE/BC) region relevant to public health nutrition, particularly in creation of food composition databases (FCDBs), applying dietary intake assessment and monitoring tools, and harmonizing methodology for nutrition surveillance. Balkan Food Platform was established by a Memorandum of Understanding among EuroFIR AISBL, Institute for Medical Research, Belgrade, Capacity Development Network in Nutrition in CEE - CAPNUTRA and institutions from nine countries in the region. Inventory on FCDB status identified lack of harmonized and standardized research tools. To strengthen harmonization in CEE/BC in line with European research trends, the Network members collaborated in development of a Regional FCDB, using web-based food composition data base management software following EuroFIR standards. Comprehensive nutrition assessment and planning tool - DIET ASSESS & PLAN could enable synchronization of nutrition surveillance across countries. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. DaMold: A data-mining platform for variant annotation and visualization in molecular diagnostics research.

    Science.gov (United States)

    Pandey, Ram Vinay; Pabinger, Stephan; Kriegner, Albert; Weinhäusel, Andreas

    2017-07-01

    Next-generation sequencing (NGS) has become a powerful and efficient tool for routine mutation screening in clinical research. As each NGS test yields hundreds of variants, the current challenge is to meaningfully interpret the data and select potential candidates. Analyzing each variant while manually investigating several relevant databases to collect specific information is a cumbersome and time-consuming process, and it requires expertise and familiarity with these databases. Thus, a tool that can seamlessly annotate variants with clinically relevant databases under one common interface would be of great help for variant annotation, cross-referencing, and visualization. This tool would allow variants to be processed in an automated and high-throughput manner and facilitate the investigation of variants in several genome browsers. Several analysis tools are available for raw sequencing-read processing and variant identification, but an automated variant filtering, annotation, cross-referencing, and visualization tool is still lacking. To fulfill these requirements, we developed DaMold, a Web-based, user-friendly tool that can filter and annotate variants and can access and compile information from 37 resources. It is easy to use, provides flexible input options, and accepts variants from NGS and Sanger sequencing as well as hotspots in VCF and BED formats. DaMold is available as an online application at http://damold.platomics.com/index.html, and as a Docker container and virtual machine at https://sourceforge.net/projects/damold/. © 2017 Wiley Periodicals, Inc.

  8. Analyzing HT-SELEX data with the Galaxy Project tools--A web based bioinformatics platform for biomedical research.

    Science.gov (United States)

    Thiel, William H; Giangrande, Paloma H

    2016-03-15

    The development of DNA and RNA aptamers for research as well as diagnostic and therapeutic applications is a rapidly growing field. In the past decade, the process of identifying aptamers has been revolutionized with the advent of high-throughput sequencing (HTS). However, bioinformatics tools that enable the average molecular biologist to analyze these large datasets and expedite the identification of candidate aptamer sequences have been lagging behind the HTS revolution. The Galaxy Project was developed in order to efficiently analyze genome, exome, and transcriptome HTS data, and we have now applied these tools to aptamer HTS data. The Galaxy Project's public webserver is an open source collection of bioinformatics tools that are powerful, flexible, dynamic, and user friendly. The online nature of the Galaxy webserver and its graphical interface allow users to analyze HTS data without compiling code or installing multiple programs. Herein we describe how tools within the Galaxy webserver can be adapted to pre-process, compile, filter and analyze aptamer HTS data from multiple rounds of selection. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Pacific Research Platform - Creation of a West Coast Big Data Freeway System Applied to the CONNected objECT (CONNECT) Data Mining Framework for Earth Science Knowledge Discovery

    Science.gov (United States)

    Sellars, S. L.; Nguyen, P.; Tatar, J.; Graham, J.; Kawsenuk, B.; DeFanti, T.; Smarr, L.; Sorooshian, S.; Ralph, M.

    2017-12-01

    A new era in computational earth sciences is within our grasps with the availability of ever-increasing earth observational data, enhanced computational capabilities, and innovative computation approaches that allow for the assimilation, analysis and ability to model the complex earth science phenomena. The Pacific Research Platform (PRP), CENIC and associated technologies such as the Flash I/O Network Appliance (FIONA) provide scientists a unique capability for advancing towards this new era. This presentation reports on the development of multi-institutional rapid data access capabilities and data pipeline for applying a novel image characterization and segmentation approach, CONNected objECT (CONNECT) algorithm to study Atmospheric River (AR) events impacting the Western United States. ARs are often associated with torrential rains, swollen rivers, flash flooding, and mudslides. CONNECT is computationally intensive, reliant on very large data transfers, storage and data mining techniques. The ability to apply the method to multiple variables and datasets located at different University of California campuses has previously been challenged by inadequate network bandwidth and computational constraints. The presentation will highlight how the inter-campus CONNECT data mining framework improved from our prior download speeds of 10MB/s to 500MB/s using the PRP and the FIONAs. We present a worked example using the NASA MERRA data to describe how the PRP and FIONA have provided researchers with the capability for advancing knowledge about ARs. Finally, we will discuss future efforts to expand the scope to additional variables in earth sciences.

  10. Observations of fine-scale transport structure in the upper troposphere from the High-performance Instrumented Airborne Platform for Environmental Research

    Science.gov (United States)

    Bowman, Kenneth P.; Pan, Laura L.; Campos, Teresa; Gao, Rushan

    2007-09-01

    The Progressive Science Mission in December 2005 was the first research use of the new NCAR High-performance Instrumented Airborne Platform for Environmental Research (HIAPER) aircraft. The Stratosphere-Troposphere Analyses of Regional Transport (START) component of the mission was designed to investigate the dynamical and chemical structure of the upper troposphere and lower stratosphere. Flight 5 of the Progressive Science mission was a START flight that sampled near the tropopause in an area between the main jet stream and a large, quasi-stationary, cutoff low. The large-scale flow in this region was characterized by a hyperbolic (saddle) point. In this study the in situ measurements by HIAPER are combined with flow analyses and satellite data to investigate the quasi-isentropic stirring of trace species in the upper troposphere. As expected from theoretical considerations, strong stretching and folding deformation of the flow near the hyperbolic point resulted in rapid filamentation of air masses and sharp gradients of constituents. Calculations of the stirring using operational meteorological analyses from the NCEP Global Forecast System model produced excellent agreement with HIAPER and satellite observations of trace species. Back trajectories indicate that elevated ozone levels in some filaments likely came from a large stratospheric intrusion that occurred upstream in the jet over the north Pacific Ocean. The methods presented here can be used with operational forecasts for future flight planning.

  11. Microgravity Platforms

    Science.gov (United States)

    Del Basso, Steve

    2000-01-01

    The world's space agencies have been conducting microgravity research since the beginning of space flight. Initially driven by the need to understand the impact of less than- earth gravity physics on manned space flight, microgravity research has evolved into a broad class of scientific experimentation that utilizes extreme low acceleration environments. The U.S. NASA microgravity research program supports both basic and applied research in five key areas: biotechnology - focusing on macro-molecular crystal growth as well as the use of the unique space environment to assemble and grow mammalian tissue; combustion science - focusing on the process of ignition, flame propagation, and extinction of gaseous, liquid, and solid fuels; fluid physics - including aspects of fluid dynamics and transport phenomena; fundamental physics - including the study of critical phenomena, low-temperature, atomic, and gravitational physics; and materials science - including electronic and photonic materials, glasses and ceramics, polymers, and metals and alloys. Similar activities prevail within the Chinese, European, Japanese, and Russian agencies with participation from additional international organizations as well. While scientific research remains the principal objective behind these program, all hope to drive toward commercialization to sustain a long range infrastructure which .benefits the national technology and economy. In the 1997 International Space Station Commercialization Study, conducted by the Potomac Institute for Policy Studies, some viable microgravity commercial ventures were identified, however, none appeared sufficiently robust to privately fund space access at that time. Thus, government funded micro gravity research continues on an evolutionary path with revolutionary potential.

  12. Achievement report for fiscal 1998 on research and development project for university coordinated type industrial science technologies. Research and development on platform for designing high functional materials (development for practical use of technologies related to rationalization of energy use); 1998 nendo kokino zairyo sekkei platform no kenkyu kaihatsu. Energy shiyo gorikia kankei gijutsu jitsuyoka kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    This paper reports research achievements in fiscal 1998 for a platform for designing high functional materials. Since coarse-grained models used in molecular dynamics (MD) simulation are diversified depending on materials, phenomena and properties, a general purpose MD engine that can simulate them freely was designed. Methods were developed to determine the potentials of coarse-grained models from the atomistic models. In polymer melts, very slow movements caused by entanglements have a substantially important role, which are difficult to be studied by usual MD simulations. Therefore, fiscal 1998 has devised a coarse-grained model to handle slow movements of straight-chain polymers, and a rheological forecast program was prepared. Studies are also being made on meso-scale structures sufficiently large as compared to atoms and on dynamic property forecast. Works were carried out to develop a simulator, in which polymeric phenomena with large spatio-temporal scale are applied with a continuity model to solve the equation thereof. Improvements were given on the hardware/software environments required for developing simulation engines and platforms for mesoscopic region. (NEDO)

  13. Delayed XBT data collected from the FRANKLIN and other platforms by Commonwealth Scientific Industrial Research Organization (CSIRO) from 25 February 2000 to 4 December 2000 (NODC Accession 0000430)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — XBT data were collected in the Indian Ocean from multiple platforms from 25 February 2000 to 4 December 2000. Data were collected by the CommonWealth Scientific...

  14. The European Photovoltaic Technology Platform

    International Nuclear Information System (INIS)

    Nowak, S.; Aulich, H.; Bal, J.L.; Dimmler, B.; Garnier, A.; Jongerden, G.; Luther, J.; Luque, A.; Milner, A.; Nelson, D.; Pataki, I.; Pearsall, N.; Perezagua, E.; Pietruszko, S.; Rehak, J.; Schellekens, E.; Shanker, A.; Silvestrini, G.; Sinke, W.; Willemsen, H.

    2006-05-01

    The European Photovoltaic Technology Platform is one of the European Technology Platforms, a new instrument proposed by the European Commission. European Technology Platforms (ETPs) are a mechanism to bring together all interested stakeholders to develop a long-term vision to address a specific challenge, create a coherent, dynamic strategy to achieve that vision and steer the implementation of an action plan to deliver agreed programmes of activities and optimise the benefits for all parties. The European Photovoltaic Technology Platform has recently been established to define, support and accompany the implementation of a coherent and comprehensive strategic plan for photovoltaics. The platform will mobilise all stakeholders sharing a long-term European vision for PV, helping to ensure that Europe maintains and improves its industrial position. The platform will realise a European Strategic Research Agenda for PV for the next decade(s). Guided by a Steering Committee of 20 high level decision-makers representing all relevant European PV Stakeholders, the European PV Technology Platform comprises 4 Working Groups dealing with the subjects policy and instruments; market deployment; science, technology and applications as well as developing countries and is supported by a secretariat

  15. The Prodiguer Messaging Platform

    Science.gov (United States)

    Denvil, S.; Greenslade, M. A.; Carenton, N.; Levavasseur, G.; Raciazek, J.

    2015-12-01

    CONVERGENCE is a French multi-partner national project designed to gather HPC and informatics expertise to innovate in the context of running French global climate models with differing grids and at differing resolutions. Efficient and reliable execution of these models and the management and dissemination of model output are some of the complexities that CONVERGENCE aims to resolve.At any one moment in time, researchers affiliated with the Institut Pierre Simon Laplace (IPSL) climate modeling group, are running hundreds of global climate simulations. These simulations execute upon a heterogeneous set of French High Performance Computing (HPC) environments. The IPSL's simulation execution runtime libIGCM (library for IPSL Global Climate Modeling group) has recently been enhanced so as to support hitherto impossible realtime use cases such as simulation monitoring, data publication, metrics collection, simulation control, visualizations … etc. At the core of this enhancement is Prodiguer: an AMQP (Advanced Message Queue Protocol) based event driven asynchronous distributed messaging platform. libIGCM now dispatches copious amounts of information, in the form of messages, to the platform for remote processing by Prodiguer software agents at IPSL servers in Paris. Such processing takes several forms: Persisting message content to database(s); Launching rollback jobs upon simulation failure; Notifying downstream applications; Automation of visualization pipelines; We will describe and/or demonstrate the platform's: Technical implementation; Inherent ease of scalability; Inherent adaptiveness in respect to supervising simulations; Web portal receiving simulation notifications in realtime.

  16. Stratospheric Platforms for Monitoring Purposes

    International Nuclear Information System (INIS)

    Konigorski, D.; Gratzel, U.; Obersteiner, M.; Schneidereit, M.

    2010-01-01

    Stratospheric platforms are emerging systems based on challenging technology. Goal is to create a platform, payload, and mission design which is able to complement satellite services on a local scale. Applications are close to traditional satellite business in telecommunication, navigation, science, and earth observation and include for example mobile telecommunications, navigation augmentation, atmospheric research, or border control. Stratospheric platforms could potentially support monitoring activities related to safeguards, e.g. by imagery of surfaces, operational conditions of nuclear facilities, and search for undeclared nuclear activities. Stratospheric platforms are intended to be flown in an altitude band between 16 and 30 km, above 16-20 km to take advantage of usually lower winds facilitating station keeping, below 30 km to limit the challenges to achieve a reasonable payload at acceptable platform sizes. Stratospheric platforms could substitute satellites which are expensive and lack upgrade capabilities for new equipment. Furthermore they have practically an unlimited time over an area of interest. It is intended to keep the platforms operational and maintenance free on a 24/7 basis with an average deployment time of 3 years. Geostationary satellites lack resolution. Potential customers like Armed Forces, National Agencies and commercial customers have indicated interest in the use of stratospheric platforms. Governmental entities are looking for cheaper alternatives to communications and surveillance satellites and stratospheric platforms could offer the following potential advantages: Lower operational cost than satellite or UAV (Unmanned Aerial Vehicles) constellation (fleet required); Faster deployment than satellite constellation; Repositioning capability and ability to loiter as required; Persistent long-term real-time services over a fairly large regional spot; Surge capability: Able to extend capability (either monitoring or communications

  17. Platform treatment

    International Nuclear Information System (INIS)

    Jammazi, Rochdi; M'henni, Wafa

    2008-01-01

    Our project consists of making of a punt forms test for the radioactive treatment in the research's unit of the CNSTN .First a complete functional analysis is carried out, this analysis comprises a comparative study between our work and a design already established in a preparatory project, it emphasizes the failures whose made proof the old design .Second the metallurgical study which must lead on the choice of materials is in its turn carried out. Thirdly the design with all the details and the plans is carried out by the intermediary of the software CATIA. This design is accompanied by the various bodies's dimensioning and the calculation of the various states of stresses to which the parts of the system are subjected: buckling, inflection fourthly an automatic study is carried out, this study contains the automation's step of the system using the software, SIMATIC STEP 7. It also contains the choice of the various position and velocity pick-ups. Finally we will finish by the presentation of maintenance and safety's instructions of the system and the operator working in this research's . (Author)

  18. sCLIP-an integrated platform to study RNA-protein interactomes in biomedical research: identification of CSTF2tau in alternative processing of small nuclear RNAs.

    Science.gov (United States)

    Kargapolova, Yulia; Levin, Michal; Lackner, Karl; Danckwardt, Sven

    2017-06-02

    RNA-binding proteins (RBPs) are central for gene expression by controlling the RNA fate from birth to decay. Various disorders arising from perturbations of RNA-protein interactions document their critical function. However, deciphering their function is complex, limiting the general functional elucidation of this growing class of proteins and their contribution to (patho)physiology. Here, we present sCLIP, a simplified and robust platform for genome-wide interrogation of RNA-protein interactomes based on crosslinking-immunoprecipitation and high-throughput sequencing. sCLIP exploits linear amplification of the immunoprecipitated RNA improving the complexity of the sequencing-library despite significantly reducing the amount of input material and omitting several purification steps. Additionally, it permits a radiolabel-free visualization of immunoprecipitated RNA. In a proof of concept, we identify that CSTF2tau binds many previously not recognized RNAs including histone, snoRNA and snRNAs. CSTF2tau-binding is associated with internal oligoadenylation resulting in shortened snRNA isoforms subjected to rapid degradation. We provide evidence for a new mechanism whereby CSTF2tau controls the abundance of snRNAs resulting in alternative splicing of several RNAs including ANK2 with critical roles in tumorigenesis and cardiac function. Combined with a bioinformatic pipeline sCLIP thus uncovers new functions for established RBPs and fosters the illumination of RBP-protein interaction landscapes in health and disease. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  19. SU-F-T-508: A Collimator-Based 3-Dimensional Grid Therapy Technique in a Small Animal Radiation Research Platform

    International Nuclear Information System (INIS)

    Jin, J; Kong, V; Zhang, H

    2016-01-01

    Purpose: Three dimensional (3D) Grid Therapy using MLC-based inverse-planning has been proposed to achieve the features of both conformal radiotherapy and spatially fractionated radiotherapy, which may deliver very high dose in a single fraction to portions of a large tumor with relatively low normal tissue dose. However, the technique requires relatively long delivery time. This study aims to develop a collimator-based 3D grid therapy technique. Here we report the development of the technique in a small animal radiation research platform. Methods: Similar as in the MLC-based technique, 9 non-coplanar beams in special channeling directions were used for the 3D grid therapy technique. Two specially designed grid collimators were fabricated, and one of them was selectively used to match the corresponding gantry/couch angles so that the grid opening of all 9 beams are met in the 3D space in the target. A stack of EBT3 films were used as 3D dosimetry to demonstrate the 3D grid-like dose distribution in the target. Three 1-mm beams were delivered to the stack of films in the area outside the target for alignment when all the films were scanned to reconstruct the 3D dosimtric image. Results: 3D film dosimetry showed a lattice-like dose distribution in the 3D target as well as in the axial, sagittal and coronal planes. The dose outside the target also showed a grid like dose distribution, and the average dose gradually decreased with the distance to the target. The peak to valley ratio was approximately 5:1. The delivery time was 7 minutes for 18 Gy peak dose, comparing to 6 minutes to deliver a 18-Gy 3D conformal plan. Conclusion: We have demonstrated the feasibility of the collimator-based 3D grid therapy technique which can significantly reduce delivery time comparing to MLC-based inverse planning technique.

  20. SU-F-T-508: A Collimator-Based 3-Dimensional Grid Therapy Technique in a Small Animal Radiation Research Platform

    Energy Technology Data Exchange (ETDEWEB)

    Jin, J; Kong, V; Zhang, H [Georgia Regents University, Augusta, GA (Georgia)

    2016-06-15

    Purpose: Three dimensional (3D) Grid Therapy using MLC-based inverse-planning has been proposed to achieve the features of both conformal radiotherapy and spatially fractionated radiotherapy, which may deliver very high dose in a single fraction to portions of a large tumor with relatively low normal tissue dose. However, the technique requires relatively long delivery time. This study aims to develop a collimator-based 3D grid therapy technique. Here we report the development of the technique in a small animal radiation research platform. Methods: Similar as in the MLC-based technique, 9 non-coplanar beams in special channeling directions were used for the 3D grid therapy technique. Two specially designed grid collimators were fabricated, and one of them was selectively used to match the corresponding gantry/couch angles so that the grid opening of all 9 beams are met in the 3D space in the target. A stack of EBT3 films were used as 3D dosimetry to demonstrate the 3D grid-like dose distribution in the target. Three 1-mm beams were delivered to the stack of films in the area outside the target for alignment when all the films were scanned to reconstruct the 3D dosimtric image. Results: 3D film dosimetry showed a lattice-like dose distribution in the 3D target as well as in the axial, sagittal and coronal planes. The dose outside the target also showed a grid like dose distribution, and the average dose gradually decreased with the distance to the target. The peak to valley ratio was approximately 5:1. The delivery time was 7 minutes for 18 Gy peak dose, comparing to 6 minutes to deliver a 18-Gy 3D conformal plan. Conclusion: We have demonstrated the feasibility of the collimator-based 3D grid therapy technique which can significantly reduce delivery time comparing to MLC-based inverse planning technique.

  1. Modul.LES: a multi-compartment, multi-organism aquatic life support system as experimental platform for research in ∆g

    Science.gov (United States)

    Hilbig, Reinhard; Anken, Ralf; Grimm, Dennis

    nitrogene-cycle (concentration of ammonium, nitrite and nitrate) as well as conductivity will be measured. For this long term mission an external food supply as has been used with OmegaHab is not sufficient and, therefore, in OmegaHab-XP a nutrition compartment has been added. OmegaHab-XP is a multi-trophic system, designed as a basic concept and test-bed for future multi-modular platform Modul.LES. OmegaHab-XP comprises four different trophic lev-els. The algae experimental container is used as CO2 / O2 exchanger and serves as oxygen source for all heterotrophic organisms. The fish compartment is divided into two areas -namely a hatchery (larval cichlid fish Oreochromis mossambicus) and a fish tank (subadult cichlids). Once the yolk sack is resorbed (stage 19) the juvenile fish are capable to leave the hatchery via escapements into the fish compartment. In order to enable the development of fish from larval yolk sack stages to subadult fish a nutrition compartment is enclosed: In this nutrition compartment the crustacean Hyalella azteca will reproduce and build up a stable population by feeding on the Rigid Hornwort (Ceratophyllum demersum). Younger crustaceans can cross the barrier to the fish tank and can serve as nutrition for fully developed subadult fish. Waste products of all organisms will be assimilated by the water snail Biomphalaria glabrata. The scientific concept of Modul.LES is to establish a multidisciplinary framework of scientists and areas of scientific research (biophysics, molecular-organismic biology, biochemistry etc.) to analyze impacts of g on plants and animals.

  2. The U.S. Department of Energy's Reference Facility for Offshore Renewable Energy (RFORE): A New Platform for Research and Development (Invited)

    Science.gov (United States)

    Shaw, W. J.

    2013-12-01

    , humidity, and turbulence sensors at nominally eight levels to a maximum measurement height of at least 100 m. In addition, remote sensing systems for atmospheric dynamic and thermodynamic profiles, sea state measurements including wave spectra, and subsurface measurements of current, temperature, and salinity profiles will be measured. Eventually, measurements from the platform are anticipated to include monitoring of marine and avian life as well as bats. All data collected at the RFORE will be archived and made available to all interested users. The RFORE is currently planned to be built on the structure of the Chesapeake Light Tower, approximately 25 km east of Virginia Beach, Virginia. This development is an active collaboration among U.S. DOE headquarters staff, the National Renewable Energy Laboratory (NREL), and Pacific Northwest National Laboratory (PNNL). NREL will design, construct, and operate the facility. PNNL will develop the research agenda, including the data archive. This presentation emphasizes the measurement capabilities of the facility in the context of research applications, user access to the data through the archive, and plans for user engagement and research management of the facility.

  3. Elements of the geological structure of the Western Siberian platform determined from a review of fine-scale satellite photographs in oil and gas prospecting research

    Energy Technology Data Exchange (ETDEWEB)

    Borovskii, V V; Klopov, A L; Peskovskii, I D; Podsosova, L L

    1980-01-01

    Dislocations with breaks in continuity and annular objects are identified on fine-scale satellite photographs within the region of the Western Siberian platform. Based on an integrated interpretation of the geological and geophysical data, it is predicted that there exists a relation between the annular objects and the geological structure of deep portions of the earth's crust, the pre-Jurassic basement, and certain levels of the platform mantle. Procedural techniques for the use of magnetic and gravitional data for the purpose of obtaining information about the geological nature of the identified objects are considered.

  4. The Big Challenge in Big Earth Science Data: Maturing to Transdisciplinary Data Platforms that are Relevant to Government, Research and Industry

    Science.gov (United States)

    Wyborn, Lesley; Evans, Ben

    2016-04-01

    scientific domain silos, including into the humanities and social sciences. Furthermore there is increasing desire for these 'Big Data' data infrastructures to prove their value not only as platforms for scientific discovery, but to also support the development of evidence-based government policies, economic growth, and private-sector opportunities. The capacity of these transdisciplinary data repositories leads to many new exciting opportunities for the next generation of large-scale data integration, but there is an emerging suite of data challenges that now need to be tackled. Many large volume data sets have historically been developed within traditional domain silos and issues such as difference of standards (informal and formal), the data conventions, the lack of controlled or even uniform vocabularies, the non-existent/not machine-accessible semantic information, and bespoke or unclear copyrights and licensing are becoming apparent. The different perspectives and approaches of the various communities have also started to come to the fore; particularly the dominant file based approach of the big data generating science communities versus the database approach of the point observational communities; and the multidimensional approach of the climate and oceans community versus the traditional 2D approach of the GIS/spatial community. Addressing such challenges is essential to fully unlock online access to all relevant data to enable the maturing of research to the transdisciplinary paradigm.

  5. eGender-from e-Learning to e-Research: a web-based interactive knowledge-sharing platform for sex- and gender-specific medical education.

    Science.gov (United States)

    Seeland, Ute; Nauman, Ahmad T; Cornelis, Alissa; Ludwig, Sabine; Dunkel, Mathias; Kararigas, Georgios; Regitz-Zagrosek, Vera

    2016-01-01

    Sex and Gender Medicine is a novel discipline that provides equitable medical care for society and improves outcomes for both male and female patients. The integration of sex- and gender-specific knowledge into medical curricula is limited due to adequate learning material, systematic teacher training and an innovative communication strategy. We aimed at initiating an e-learning and knowledge-sharing platform for Sex and Gender Medicine, the eGender platform (http://egender.charite.de), to ensure that future doctors and health professionals will have adequate knowledge and communication skills on sex and gender differences in order to make informed decisions for their patients. The web-based eGender knowledge-sharing platform was designed to support the blended learning pedagogical teaching concept and follows the didactic concept of constructivism. Learning materials developed by Sex and Gender Medicine experts of seven universities have been used as the basis for the new learning tools . The content of these tools is patient-centered and provides add-on information on gender-sensitive aspects of diseases. The structural part of eGender was designed and developed using the open source e-learning platform Moodle. The eGender platform comprises an English and a German version of e-learning modules: one focusing on basic knowledge and seven on specific medical disciplines. Each module consists of several courses corresponding to a disease or symptom complex. Self-organized learning has to be managed by using different learning tools, e.g., texts and audiovisual material, tools for online communication and collaborative work. More than 90 users from Europe registered for the eGender Medicine learning modules. The most frequently accessed module was "Gender Medicine-Basics" and the users favored discussion forums. These e-learning modules fulfill the quality criteria for higher education and are used within the elective Master Module "Gender Medicine

  6. Launching platforms for user-generated content

    OpenAIRE

    Batista, Guilherme Luís Caroço

    2015-01-01

    Field lab: Entrepreneurial and innovative ventures This paper intends to discuss and absorb the Best Practices employed by successful User- Generated Content (UGC)1 platforms and constitute a guide on how to launch a platform without having a cyclical lack of content and users. Research shows that companies have resorted to integration with mature UGC platforms, and providing content by themselves, in an initial state. I conclude that integration possibilities should be explore...

  7. Data Platforms and Cities

    DEFF Research Database (Denmark)

    Blok, Anders; Courmont, Antoine; Hoyng, Rolien

    2017-01-01

    This section offers a series of joint reflections on (open) data platform from a variety of cases, from cycling, traffic and mapping to activism, environment and data brokering. Data platforms play a key role in contemporary urban governance. Linked to open data initiatives, such platforms are of...

  8. ITS Platform North Denmark

    DEFF Research Database (Denmark)

    Lahrmann, Harry; Agerholm, Niels; Juhl, Jens

    2012-01-01

    This paper presents the project entitled “ITS Platform North Denmark” which is used as a test platform for Intelligent Transportation System (ITS) solutions. The platform consists of a newly developed GNSS/GPRS On Board Unit (OBU) to be installed in 500 cars, a backend server and a specially...

  9. Continuous Platform Development

    DEFF Research Database (Denmark)

    Nielsen, Ole Fiil

    low risks and investments but also with relatively fuzzy results. When looking for new platform projects, it is important to make sure that the company and market is ready for the introduction of platforms, and to make sure that people from marketing and sales, product development, and downstream......, but continuous product family evolution challenges this strategy. The concept of continuous platform development is based on the fact that platform development should not be a one-time experience but rather an ongoing process of developing new platforms and updating existing ones, so that product family...

  10. Disentangling Competition Among Platform Driven Strategic Groups

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    2018-01-01

    for the mobile payment market in the United Kingdom as our empirical setting. By conceptualizing digital platforms as layered modular architectures and embracing the theoretical lens of strategic groups, this study supplements prior research by deriving a taxonomy of platform profiles that is grounded...... delivery architecture. The preceding attributes of value creation architecture and value delivery architecture aided us in identifying six profiles associated with mobile payment platforms, which in turn led us to advance three competitive strategies that could be pursued by digital platforms in network...

  11. Research and practice on building social interactive learning based open course platform and teaching mode%社交互动式高职网络公开课平台和教学模式的构建

    Institute of Scientific and Technical Information of China (English)

    王静; 汪昀

    2012-01-01

    通过将积木块技术和项目化教学方式引入到专业共享型网络公开课平台的建设,探索适合高职的网络公开课课程的社交互动学习模式,同时通过对学习模式的研究完善网络公开课平台的构建。%Practical research on Dynamic modular designed Open Course platform based on building blocks technology and project teaching mode is to explore a social interactive learning mode of High Vocational Education. The exploration is also for improving the construction of open course platform and breaking local resources sharing barriers.

  12. Cross-Platform Technologies

    Directory of Open Access Journals (Sweden)

    Maria Cristina ENACHE

    2017-04-01

    Full Text Available Cross-platform - a concept becoming increasingly used in recent years especially in the development of mobile apps, but this consistently over time and in the development of conventional desktop applications. The notion of cross-platform software (multi-platform or platform-independent refers to a software application that can run on more than one operating system or computing architecture. Thus, a cross-platform application can operate independent of software or hardware platform on which it is execute. As a generic definition presents a wide range of meanings for purposes of this paper we individualize this definition as follows: we will reduce the horizon of meaning and we use functionally following definition: a cross-platform application is a software application that can run on more than one operating system (desktop or mobile identical or in a similar way.

  13. Geometric information provider platform

    Directory of Open Access Journals (Sweden)

    Meisam Yousefzadeh

    2015-07-01

    Full Text Available Renovation of existing buildings is known as an essential stage in reduction of the energy loss. Considerable part of renovation process depends on geometric reconstruction of building based on semantic parameters. Following many research projects which were focused on parameterizing the energy usage, various energy modelling methods were developed during the last decade. On the other hand, by developing accurate measuring tools such as laser scanners, the interests of having accurate 3D building models are rapidly growing. But the automation of 3D building generation from laser point cloud or detection of specific objects in that is still a challenge.  The goal is designing a platform through which required geometric information can be efficiently produced to support energy simulation software. Developing a reliable procedure which extracts required information from measured data and delivers them to a standard energy modelling system is the main purpose of the project.

  14. DATABASE REPLICATION IN HETEROGENOUS PLATFORM

    OpenAIRE

    Hendro Nindito; Evaristus Didik Madyatmadja; Albert Verasius Dian Sano

    2014-01-01

    The application of diverse database technologies in enterprises today is increasingly a common practice. To provide high availability and survavibality of real-time information, a database replication technology that has capability to replicate databases under heterogenous platforms is required. The purpose of this research is to find the technology with such capability. In this research, the data source is stored in MSSQL database server running on Windows. The data will be replicated to MyS...

  15. Design and Development of a Rapid Research, Design, and Development Platform for In-Situ Testing of Tools and Concepts for Trajectory-Based Operations

    Science.gov (United States)

    Underwood, Matthew C.

    2017-01-01

    To provide justification for equipping a fleet of aircraft with avionics capable of supporting trajectory-based operations, significant flight testing must be accomplished. However, equipping aircraft with these avionics and enabling technologies to communicate the clearances required for trajectory-based operations is cost-challenging using conventional avionics approaches. This paper describes an approach to minimize the costs and risks of flight testing these technologies in-situ, discusses the test-bed platform developed, and highlights results from a proof-of-concept flight test campaign that demonstrates the feasibility and efficiency of this approach.

  16. Microneedle Platforms for Cell Analysis

    KAUST Repository

    Kavaldzhiev, Mincho

    2017-11-01

    -dependent delivery rate has been found. The electromagnetic delivery concept is particularly promising for future in-vivo applications. Finally, the micro-needle platforms developed in this work will provide researchers with new capabilities that will help them to further advance the field of mechanobiology, drug delivery treatments, stem cells research and more. The proposed platforms are capable of applying various stimuli, analyzing cell responses in real time, drug delivery, and they also have the potential to add additional functionalities in the future.

  17. Lab-on-fiber optofluidic platform for in-situ study of therapeutic peptides and bacterial response (Rising Researcher Presentation) (Conference Presentation)

    Science.gov (United States)

    Tian, Fei; Yang, Fan; Liang, Junfeng

    2017-05-01

    Hospital acquired infections in indwelling device have become a life-threatening issue accompanied by the wide use of medical devices and implants. The infection process typically involves the attachment, growth and eventual assemblage of microbial cells into biofilms, with the latter exhibiting extremely higher antibiotic tolerance than planktonic bacteria. Surface constructed antimicrobial coatings offer a viable solution for bacteria responsive antibiotic strategy in medical devices such as catheter and stents. Therapeutic peptide has pioneered the field for their attractive pharmacological profile with broad antibacterial spectrum, great efficacy and long life-span. It has been a common practice to separately assess bacteria responses through commercially available activity assay kits after their exposure to antibiotic coatings, limiting the assessment of their activity in vitro with a discontinuous fashion. We developed and demonstrated an innovative all-optical lab-on-fiber optofluidic platform (LOFOP) to fill in this technical gap by allowing in situ measurement of the bacteria attachment in a continuous manner. This LOFOP allows for evaluation of drug release and resultant bacterial response by integrating glass capillary with lytic peptide-containing LbL-coated long period graing (LPG) as its core. S. aureus suspension is introduced through the assembled optofluidic platform with the capillary and the peptide-coated LPG. The efficacy of the peptide-containing coating is evaluated in situ by monitoring the attachment of bacteria and the ensuing development of biofilms using the LPG. LPG without antimicrobial coatings will be explored and compared as control.

  18. ADMS Evaluation Platform

    Energy Technology Data Exchange (ETDEWEB)

    2018-01-23

    Deploying an ADMS or looking to optimize its value? NREL offers a low-cost, low-risk evaluation platform for assessing ADMS performance. The National Renewable Energy Laboratory (NREL) has developed a vendor-neutral advanced distribution management system (ADMS) evaluation platform and is expanding its capabilities. The platform uses actual grid-scale hardware, large-scale distribution system models, and advanced visualization to simulate realworld conditions for the most accurate ADMS evaluation and experimentation.

  19. Platform development supportedby gaming

    DEFF Research Database (Denmark)

    Mikkola, Juliana Hsuan; Hansen, Poul H. Kyvsgård

    2007-01-01

    The challenge of implementing industrial platforms in practice can be described as a configuration problem caused by high number of variables, which often have contradictory influences on the total performance of the firm. Consequently, the specific platform decisions become extremely complex......, possibly increasing the strategic risks for the firm. This paper reports preliminary findings on platform management process at LEGO, a Danish toy company.  Specifically, we report the process of applying games combined with simulations and workshops in the platform development. We also propose a framework...

  20. Omnidirectional holonomic platforms

    International Nuclear Information System (INIS)

    Pin, F.G.; Killough, S.M.

    1994-01-01

    This paper presents the concepts for a new family of wheeled platforms which feature full omnidirectionality with simultaneous and independently controlled rotational and translational motion capabilities. The authors first present the orthogonal-wheels concept and the two major wheel assemblies on which these platforms are based. They then describe how a combination of these assemblies with appropriate control can be used to generate an omnidirectional capability for mobile robot platforms. The design and control of two prototype platforms are then presented and their respective characteristics with respect to rotational and translational motion control are discussed

  1. Platform decommissioning costs

    International Nuclear Information System (INIS)

    Rodger, David

    1998-01-01

    There are over 6500 platforms worldwide contributing to the offshore oil and gas production industry. In the North Sea there are around 500 platforms in place. There are many factors to be considered in planning for platform decommissioning and the evaluation of options for removal and disposal. The environmental impact, technical feasibility, safety and cost factors all have to be considered. This presentation considers what information is available about the overall decommissioning costs for the North Sea and the costs of different removal and disposal options for individual platforms. 2 figs., 1 tab

  2. [se-atlas - the health service information platform for people with rare diseases : Supporting research on medical care institutions and support groups].

    Science.gov (United States)

    Haase, Johanna; Wagner, Thomas O F; Storf, Holger

    2017-05-01

    se-atlas - the health service information platform for rare diseases - is part of the German National Action Plan for People with Rare Diseases and is funded by the German Federal Ministry of Health. The objective of se-atlas as a web-based platform is to illustrate those medical care institutions that are linked to rare diseases, in a transparent and user-friendly way. The website provides an overview of medical care institutions and support groups focusing on rare diseases in Germany. The primary target groups of se-atlas are affected patients, their relatives and physicians but can also include non-medical professionals and the general public. In order to make it easier to look up medical care institutions or support groups and optimize the search results displayed, various strategies are being developed and evaluated. Hence, the allocation of diseases to appropriate medical care institutions and support groups is currently a main focus. Since its launch in 2015, se-atlas has grown continuously and now incorporates five times more entries than were included 20 months prior. Among this data are the current rare diseases centres in Germany, which play a major role in providing patient-centred healthcare by acting as primary contact points for people with rare diseases. Further expansion and maintenance of the data base raises several organisational and software-related challenges. For one, the data should be completed by adding more high-quality information, while not neglecting the existing entries and maintaining their high level of quality in the long term.

  3. Temperature profile data collected using BT and XBT casts in the North/South Atlantic Ocean and North/South Pacific Ocean from NOAA Ship RESEARCHER and other platforms from 1987-05-20 to 1992-04-19 (NODC Accession 9200105)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using XBT and BT casts from NOAA Ship RESEARCHER and other platforms in the North/South Atlantic Ocean and North/South...

  4. Temperature profile data from XBT and BT casts in the North/South Pacific Ocean and North/South Atlantic Ocean from NOAA Ship RESEARCHER and other platforms from 1987-04-02 to 1987-11-24 (NODC Accession 8800007)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using XBT and BT casts from NOAA Ship RESEARCHER and other platforms in the North/South Pacific Ocean and North/South...

  5. Temperature profile and other data collected using CTD, BT, and XBT casts from NOAA Ship RESEARCHER and other platforms in the North/South Pacific Ocean and North/South Atlantic Ocean from 1973-01-13 to 1983-03-14 (NODC Accession 8300091)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile and other data were collected using CTD, BT, and XBT casts from NOAA Ship RESEARCHER and other platforms in the North/South Pacific Ocean and...

  6. Temperature profiles from expendable bathythermograph (XBT) casts DIAMANTINA and other Platforms from a World-Wide Distribution in support of the Integrated Global Ocean Services System (IGOSS) and the Pacific Acoustic Research Kaneohe-Alaska (PARKA) from 1966-12-12 to 1974-09-29 (NODC Accession 7500700)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — XBT data were collected from the DIAMANTINA and other Platforms in support of the Integrated Global Ocean Services System (IGOSS) and the Pacific Acoustic Research...

  7. YARP: Yet Another Robot Platform

    Directory of Open Access Journals (Sweden)

    Lorenzo Natale

    2008-11-01

    Full Text Available We describe YARP, Yet Another Robot Platform, an open-source project that encapsulates lessons from our experience in building humanoid robots. The goal of YARP is to minimize the effort devoted to infrastructure-level software development by facilitating code reuse, modularity and so maximize research-level development and collaboration. Humanoid robotics is a "bleeding edge" field of research, with constant flux in sensors, actuators, and processors. Code reuse and maintenance is therefore a significant challenge. We describe the main problems we faced and the solutions we adopted. In short, the main features of YARP include support for inter-process communication, image processing as well as a class hierarchy to ease code reuse across different hardware platforms. YARP is currently used and tested on Windows, Linux and QNX6 which are common operating systems used in robotics.

  8. Groundwater Assessment Platform

    OpenAIRE

    Podgorski, Joel; Berg, Michael

    2018-01-01

    The Groundwater Assessment Platform is a free, interactive online GIS platform for the mapping, sharing and statistical modeling of groundwater quality data. The modeling allows users to take advantage of publicly available global datasets of various environmental parameters to produce prediction maps of their contaminant of interest.

  9. Employing the Moodle platform as a VRE tool while teaching eResearch skills to Masters and PhD students

    CSIR Research Space (South Africa)

    Van Deventer, Martha J

    2012-08-01

    Full Text Available Virtual research environments (VREs) are no longer an issue of serious debate in the developed world - they provide the infrastructure for researchers to easily collaborate across a variety of borders and a variety of disciplines. Transparent...

  10. Product Platform Modeling

    DEFF Research Database (Denmark)

    Pedersen, Rasmus

    for customisation of products. In many companies these changes in the business environment have created a controversy between the need for a wide variety of products offered to the marketplace and a desire to reduce variation within the company in order to increase efficiency. Many companies use the concept...... other. These groups can be varied and combined to form different product variants without increasing the internal variety in the company. Based on the Theory of Domains, the concept of encapsulation in the organ domain is introduced, and organs are formulated as platform elements. Included......This PhD thesis has the title Product Platform Modelling. The thesis is about product platforms and visual product platform modelling. Product platforms have gained an increasing attention in industry and academia in the past decade. The reasons are many, yet the increasing globalisation...

  11. Product Platform Replacements

    DEFF Research Database (Denmark)

    Sköld, Martin; Karlsson, Christer

    2012-01-01

    . To shed light on this unexplored and growing managerial concern, the purpose of this explorative study is to identify operational challenges to management when product platforms are replaced. Design/methodology/approach – The study uses a longitudinal field-study approach. Two companies, Gamma and Omega...... replacement was chosen in each company. Findings – The study shows that platform replacements primarily challenge managers' existing knowledge about platform architectures. A distinction can be made between “width” and “height” in platform replacements, and it is crucial that managers observe this in order...... to challenge their existing knowledge about platform architectures. Issues on technologies, architectures, components and processes as well as on segments, applications and functions are identified. Practical implications – Practical implications are summarized and discussed in relation to a framework...

  12. Demand forecasting and information platform in tourism

    Directory of Open Access Journals (Sweden)

    Li Yue

    2017-05-01

    Full Text Available Information asymmetry and the bullwhip effect have been serious problems in the tourism supply chain. Based on platform theory, this paper established a mathematical model to explore the inner mechanism of a platform’s influence on stakeholders’ ability to forecast demand in tourism. Results showed that the variance of stakeholders’ demand predictions with a platform was smaller than the variance without a platform, which meant that a platform would improve predictions of demand for stakeholders. The higher information-processing ability of the platform also had other effects on demand forecasting. Research on the inner logic of the platform’s influence on stakeholders has important theoretical and realistic value. This area is worthy of further study.

  13. Implementasi dan Evaluasi Kinerja Multi Input SingleOutput Orthogonal Frequency Division Multiplexing (MISO OFDM Menggunakan Wireless Open Access Research Platform (WARP

    Directory of Open Access Journals (Sweden)

    Galih Permana Putra

    2017-01-01

    Full Text Available Teknologi komunikasi nirkabel terus berkembang untuk memenuhi kebutuhan manusia akan koneksi informasi yang cepat, pengiriman data yang berkapasitas besar dan dapat diandalkan. Di dalam proses tersebut banyak sekali gangguan yang dapat mempengaruhi penurunan kinerja komunikasi diantaranya adalah multipath fading [1]. Multi Input Single Output (MISO merupakan salah satu teknik space diversity yang menggunakan banyak antena dengan tujuan untuk mengatasi multipath fading. Adapun pada proses transmisi digunakan teknik Orthogonal Frequency-Division Multiplexing (OFDM yang bertujuan memberikan keuntungan dalam hal efisiensi pada saat transmisi data dan mampu menghindari Inter Simbol Interference (ISI. Pada penelitian ini akan dibandingkan kinerja sistem MISO OFDM dan SISO OFDM yang akan disimulasikan dan di implementasikan pada modul Wireless Open Access Penelitian Platform (WARP untuk mengevaluasi kinerja BER sebagai fungsi dari daya pancar dan jarak variasi. Parameter yang digunakan di dalam pengukuran berdasarkan IEEE 802.11 a/g karena menggunakan frekuensi 2,4 Ghz. Terdapat dua skema pengukuran yaitu SISO OFDM dan MISO OFDM dengan variasi jarak 4,6 dan 8 meter dengan variasi daya pancar -35 s/d -4 dBm dengan peningkatan gain 5 kali secara berkala. Dari dua skema yang dilaksanakan dapat disimpulkan bahwa semakin jauh jarak antara pemancar dan penerima maka dibutuhkan penambahan gain untuk menjaga kualitas data yang dikirimkan. Disamping itu, terdapat perbedaan nilai gain untuk mencapai nilai BER = dibutuhkan penambahan gain = - 33 sedangkan pada SISO OFM dibutuhkan penambahan gain = -18.

  14. Development of new experimental platform 'MARS'-Multiple Artificial-gravity Research System-to elucidate the impacts of micro/partial gravity on mice.

    Science.gov (United States)

    Shiba, Dai; Mizuno, Hiroyasu; Yumoto, Akane; Shimomura, Michihiko; Kobayashi, Hiroe; Morita, Hironobu; Shimbo, Miki; Hamada, Michito; Kudo, Takashi; Shinohara, Masahiro; Asahara, Hiroshi; Shirakawa, Masaki; Takahashi, Satoru

    2017-09-07

    This Japan Aerospace Exploration Agency project focused on elucidating the impacts of partial gravity (partial g) and microgravity (μg) on mice using newly developed mouse habitat cage units (HCU) that can be installed in the Centrifuge-equipped Biological Experiment Facility in the International Space Station. In the first mission, 12 C57BL/6 J male mice were housed under μg or artificial earth-gravity (1 g). Mouse activity was monitored daily via downlinked videos; μg mice floated inside the HCU, whereas artificial 1 g mice were on their feet on the floor. After 35 days of habitation, all mice were returned to the Earth and processed. Significant decreases were evident in femur bone density and the soleus/gastrocnemius muscle weights of μg mice, whereas artificial 1 g mice maintained the same bone density and muscle weight as mice in the ground control experiment, in which housing conditions in the flight experiment were replicated. These data indicate that these changes were particularly because of gravity. They also present the first evidence that the addition of gravity can prevent decreases in bone density and muscle mass, and that the new platform 'MARS' may provide novel insights on the molecular-mechanisms regulating biological processes controlled by partial g/μg.

  15. Combining PPI with qualitative research to engage 'harder-to-reach' populations: service user groups as co-applicants on a platform study for a trial.

    Science.gov (United States)

    Morgan, Heather; Thomson, Gill; Crossland, Nicola; Dykes, Fiona; Hoddinott, Pat

    2016-01-01

    It is recommended that research studies are carried out with or by patients and the public through their involvement from the beginning and in as many stages as possible (known as PPI). Some studies formally invite patients and the public to participate in interviews and focused group discussions to collect views about topics (known as qualitative research). In our study on financial incentives for giving up smoking in pregnancy and breastfeeding, we combined both PPI and qualitative research to include the views of women with a range of experiences of smoking and breastfeeding. We involved two mother and baby groups in disadvantaged areas of North East Scotland and North West England as research partners on our team. First, we asked members to comment on our research plans and documents, which is standard PPI. Second, we asked members to participate in voice recorded discussions, contributing to qualitative research data. These discussions revealed different views from those that we heard through research interviews. They allowed us to develop more relevant research tools and resources. Members also helped us to identify people outside the groups who we could interview. Combining involvement and participation helped us to include the views of a wide range of women from 'harder-to-reach' groups who don't usually take part in research. This was important because the research was intended for women who could benefit from incentives to stop smoking in pregnancy and breastfeed, often present in such groups. Positive continuing relationships and trust improved on involvement or participation alone. ᅟ. Patient and public involvement (PPI) in all research studies is recommended from the earliest point and in as many stages as possible. Qualitative research is also recommended in the early stages of designing complex intervention trials. Combining both together might enable inclusion of 'harder-to-reach' perspectives from the target population(s), particularly when the

  16. The vacuum platform

    Science.gov (United States)

    McNab, A.

    2017-10-01

    This paper describes GridPP’s Vacuum Platform for managing virtual machines (VMs), which has been used to run production workloads for WLCG and other HEP experiments. The platform provides a uniform interface between VMs and the sites they run at, whether the site is organised as an Infrastructure-as-a-Service cloud system such as OpenStack, or an Infrastructure-as-a-Client system such as Vac. The paper describes our experience in using this platform, in developing and operating VM lifecycle managers Vac and Vcycle, and in interacting with VMs provided by LHCb, ATLAS, ALICE, CMS, and the GridPP DIRAC service to run production workloads.

  17. Effects of multi-stakeholder platforms on multi-stakeholder innovation networks: Implications for research for development interventions targeting innovations at scale

    Science.gov (United States)

    Schut, Marc; Hermans, Frans; van Asten, Piet; Leeuwis, Cees

    2018-01-01

    Multi-stakeholder platforms (MSPs) have been playing an increasing role in interventions aiming to generate and scale innovations in agricultural systems. However, the contribution of MSPs in achieving innovations and scaling has been varied, and many factors have been reported to be important for their performance. This paper aims to provide evidence on the contribution of MSPs to innovation and scaling by focusing on three developing country cases in Burundi, Democratic Republic of Congo, and Rwanda. Through social network analysis and logistic models, the paper studies the changes in the characteristics of multi-stakeholder innovation networks targeted by MSPs and identifies factors that play significant roles in triggering these changes. The results demonstrate that MSPs do not necessarily expand and decentralize innovation networks but can lead to contraction and centralization in the initial years of implementation. They show that some of the intended next users of interventions with MSPs–local-level actors–left the innovation networks, whereas the lead organization controlling resource allocation in the MSPs substantially increased its centrality. They also indicate that not all the factors of change in innovation networks are country specific. Initial conditions of innovation networks and funding provided by the MSPs are common factors explaining changes in innovation networks across countries and across different network functions. The study argues that investigating multi-stakeholder innovation network characteristics targeted by the MSP using a network approach in early implementation can contribute to better performance in generating and scaling innovations, and that funding can be an effective implementation tool in developing country contexts. PMID:29870559

  18. Helios: a Multi-Purpose LIDAR Simulation Framework for Research, Planning and Training of Laser Scanning Operations with Airborne, Ground-Based Mobile and Stationary Platforms

    Science.gov (United States)

    Bechtold, S.; Höfle, B.

    2016-06-01

    In many technical domains of modern society, there is a growing demand for fast, precise and automatic acquisition of digital 3D models of a wide variety of physical objects and environments. Laser scanning is a popular and widely used technology to cover this demand, but it is also expensive and complex to use to its full potential. However, there might exist scenarios where the operation of a real laser scanner could be replaced by a computer simulation, in order to save time and costs. This includes scenarios like teaching and training of laser scanning, development of new scanner hardware and scanning methods, or generation of artificial scan data sets to support the development of point cloud processing and analysis algorithms. To test the feasibility of this idea, we have developed a highly flexible laser scanning simulation framework named Heidelberg LiDAR Operations Simulator (HELIOS). HELIOS is implemented as a Java library and split up into a core component and multiple extension modules. Extensible Markup Language (XML) is used to define scanner, platform and scene models and to configure the behaviour of modules. Modules were developed and implemented for (1) loading of simulation assets and configuration (i.e. 3D scene models, scanner definitions, survey descriptions etc.), (2) playback of XML survey descriptions, (3) TLS survey planning (i.e. automatic computation of recommended scanning positions) and (4) interactive real-time 3D visualization of simulated surveys. As a proof of concept, we show the results of two experiments: First, a survey planning test in a scene that was specifically created to evaluate the quality of the survey planning algorithm. Second, a simulated TLS scan of a crop field in a precision farming scenario. The results show that HELIOS fulfills its design goals.

  19. Effects of multi-stakeholder platforms on multi-stakeholder innovation networks: Implications for research for development interventions targeting innovations at scale.

    Science.gov (United States)

    Sartas, Murat; Schut, Marc; Hermans, Frans; Asten, Piet van; Leeuwis, Cees

    2018-01-01

    Multi-stakeholder platforms (MSPs) have been playing an increasing role in interventions aiming to generate and scale innovations in agricultural systems. However, the contribution of MSPs in achieving innovations and scaling has been varied, and many factors have been reported to be important for their performance. This paper aims to provide evidence on the contribution of MSPs to innovation and scaling by focusing on three developing country cases in Burundi, Democratic Republic of Congo, and Rwanda. Through social network analysis and logistic models, the paper studies the changes in the characteristics of multi-stakeholder innovation networks targeted by MSPs and identifies factors that play significant roles in triggering these changes. The results demonstrate that MSPs do not necessarily expand and decentralize innovation networks but can lead to contraction and centralization in the initial years of implementation. They show that some of the intended next users of interventions with MSPs-local-level actors-left the innovation networks, whereas the lead organization controlling resource allocation in the MSPs substantially increased its centrality. They also indicate that not all the factors of change in innovation networks are country specific. Initial conditions of innovation networks and funding provided by the MSPs are common factors explaining changes in innovation networks across countries and across different network functions. The study argues that investigating multi-stakeholder innovation network characteristics targeted by the MSP using a network approach in early implementation can contribute to better performance in generating and scaling innovations, and that funding can be an effective implementation tool in developing country contexts.

  20. The universal modular platform

    International Nuclear Information System (INIS)

    North, R.B.

    1995-01-01

    A new and patented design for offshore wellhead platforms has been developed to meet a 'fast track' requirement for increased offshore production, from field locations not yet identified. The new design uses modular construction to allow for radical changes in the water depth of the final location and assembly line efficiency in fabrication. By utilizing high strength steels and structural support from the well conductors the new design accommodates all planned production requirements on a support structure significantly lighter and less expensive than the conventional design it replaces. Twenty two platforms based on the new design were ready for installation within 18 months of the project start. Installation of the new platforms began in 1992 for drilling support and 1993 for production support. The new design has become the Company standard for all future production platforms. Large saving and construction costs have been realized through its light weight, flexibility in both positioning and water depth, and its modular construction

  1. Paper based electronics platform

    KAUST Repository

    Nassar, Joanna Mohammad; Sevilla, Galo Andres Torres; Hussain, Muhammad Mustafa

    2017-01-01

    A flexible and non-functionalized low cost paper-based electronic system platform fabricated from common paper, such as paper based sensors, and methods of producing paper based sensors, and methods of sensing using the paper based sensors

  2. USA Hire Testing Platform

    Data.gov (United States)

    Office of Personnel Management — The USA Hire Testing Platform delivers tests used in hiring for positions in the Federal Government. To safeguard the integrity of the hiring processes and ensure...

  3. National Community Solar Platform

    Energy Technology Data Exchange (ETDEWEB)

    Rupert, Bart [Clean Energy Collective, Louisville, CO (United States)

    2016-06-30

    This project was created to provide a National Community Solar Platform (NCSP) portal known as Community Solar Hub, that is available to any entity or individual who wants to develop community solar. This has been done by providing a comprehensive portal to make CEC’s solutions, and other proven community solar solutions, externally available for everyone to access – making the process easy through proven platforms to protect subscribers, developers and utilities. The successful completion of this project provides these tools via a web platform and integration APIs, a wide spectrum of community solar projects included in the platform, multiple groups of customers (utilities, EPCs, and advocates) using the platform to develop community solar, and open access to anyone interested in community solar. CEC’s Incubator project includes web-based informational resources, integrated systems for project information and billing systems, and engagement with customers and users by community solar experts. The combined effort externalizes much of Clean Energy Collective’s industry-leading expertise, allowing third parties to develop community solar without duplicating expensive start-up efforts. The availability of this platform creates community solar projects that are cheaper to build and cheaper to participate in, furthering the goals of DOE’s SunShot Initiative. Final SF 425 Final SF 428 Final DOE F 2050.11 Final Report Narrative

  4. The Path Selection of Industry-University-Research Cooperation Creation Synergism Based on the Universities and Colleges' Platform%高校平台实现产学研创新协同路径选择

    Institute of Scientific and Technical Information of China (English)

    叶宁; 罗兰芳

    2016-01-01

    产学研合作是经济与科技进步的重要动力,产学研创新协同效应是产学研发展的立足点。由于传统产学研平台的固有交流渠道、合作模式和配套服务等方面缺陷,产学研合作的政府导向明显,校企机构和社会组织力量不能较好进入和服务,对科研管理和技术创新形成阻滞。产学研合作应在平台创新过程中紧密结合网络和高校优势,有效利用高校在全面产业知识、技术、人才和网络方面条件,以较快地实现平台搭建和协同创新的路径选择。%Industry-University-Research Cooperation (IURC) is the major power for economic development and technical progress. The creation synergistic effect is the foothold of the Industry-University-Research development.Because there exist some problems in traditional platform,such as the lack of communication channels, simple cooperation mode and incomplete compatible method andobvious government orientation, school and enterprise institutions and social organization forces cannot well serve for it, which become an obstacle for scientific research management and technology innovation.IURC should closely combine the internet and university's advantages,effectively utilize the industry knowledge, technology, talent manpower and internet facilities in colleges and universities so as to realize the IURC's platform construction and creation synergistic path selection.

  5. The Platformization of the Web: Making Web Data Platform Ready

    NARCIS (Netherlands)

    Helmond, A.

    2015-01-01

    In this article, I inquire into Facebook’s development as a platform by situating it within the transformation of social network sites into social media platforms. I explore this shift with a historical perspective on, what I refer to as, platformization, or the rise of the platform as the dominant

  6. Transactional Network Platform: Applications

    Energy Technology Data Exchange (ETDEWEB)

    Katipamula, Srinivas; Lutes, Robert G.; Ngo, Hung; Underhill, Ronald M.

    2013-10-31

    In FY13, Pacific Northwest National Laboratory (PNNL) with funding from the Department of Energy’s (DOE’s) Building Technologies Office (BTO) designed, prototyped and tested a transactional network platform to support energy, operational and financial transactions between any networked entities (equipment, organizations, buildings, grid, etc.). Initially, in FY13, the concept demonstrated transactions between packaged rooftop air conditioners and heat pump units (RTUs) and the electric grid using applications or "agents" that reside on the platform, on the equipment, on a local building controller or in the Cloud. The transactional network project is a multi-lab effort with Oakridge National Laboratory (ORNL) and Lawrence Berkeley National Laboratory (LBNL) also contributing to the effort. PNNL coordinated the project and also was responsible for the development of the transactional network (TN) platform and three different applications associated with RTUs. This document describes two applications or "agents" in details, and also summarizes the platform. The TN platform details are described in another companion document.

  7. Platform-based production development

    DEFF Research Database (Denmark)

    Bossen, Jacob; Brunoe, Thomas Ditlev; Nielsen, Kjeld

    2015-01-01

    Platforms as a means for applying modular thinking in product development is relatively well studied, but platforms in the production system has until now not been given much attention. With the emerging concept of platform-based co-development the importance of production platforms is though...

  8. Development of a Modular Robotic Platform

    Directory of Open Access Journals (Sweden)

    Claudiu Ioan Cirebea

    2014-12-01

    Full Text Available In this paper a modular robotic platform is presented, for students and researchers laboratory work based on the Matlab-Simulink and dSpace real time control platform. The goal of this combination is to stimulate and to experiment with real time hardware and software in courses where mobile robotics is adopted as a motivating platform to introduce mechatronics competencies. Its many possibilities for modifications and extensions make experiments very easy. We used, for example, an omnidirectional mobile robot configuration with three Swedish wheels, whose kinematic model was simulated using Simulink. For real-time control, of the robot, the developed model has been implemented using DSpace platform DS1103.

  9. An Investigation of Digital Payment Platform Designs

    DEFF Research Database (Denmark)

    Kazan, Erol; Damsgaard, Jan

    2014-01-01

    This paper focuses on the triumph march of mobile phones that currently are annexing music players, navigation devices, and cameras as separate physical objects. The next target is set on payment. Through synthesizing available literature, we construct a framework for studying digital payment...... platforms that combines platform, technology and business design aspects. The framework is applied to conduct a comparative case study of digital payment platforms. Four types of market actors are considered: banks, mobile network operators, merchants, and startups, which are incumbents and disrupters....... By hosting third-party services, payment instruments are evolving from single-purpose to multi-functional ones. Our research extends existing payment literature from the MSP perspective to emphasize certain digital payment platform components, which impact strategies and complementary products....

  10. Fresh water generators onboard a floating platform

    International Nuclear Information System (INIS)

    Tewari, P.K.; Verma, R.K.; Misra, B.M.; Sadhulkan, H.K.

    1997-01-01

    A dependable supply of fresh water is essential for any ocean going vessel. The operating and maintenance personnel on offshore platforms and marine structures also require a constant and regular supply of fresh water to meet their essential daily needs. A seawater thermal desalination unit onboard delivers good quality fresh water from seawater. The desalination units developed by Bhabha Atomic Research Centre (BARC) suitable for ocean going vessels and offshore platforms have been discussed. Design considerations of such units with reference to floating platforms and corrosive environments have been presented. The feasibility of coupling a low temperature vacuum evaporation (LTVE) desalination plant suitable for an onboard floating platform to a PHWR nuclear power plant has also been discussed. (author). 1 ref., 3 figs, 2 tabs

  11. From powerful research platform for industrial EUV photoresist development, to world record resolution by photolithography: EUV interference lithography at the Paul Scherrer Institute

    Science.gov (United States)

    Buitrago, Elizabeth; Fallica, Roberto; Fan, Daniel; Karim, Waiz; Vockenhuber, Michaela; van Bokhoven, Jeroen A.; Ekinci, Yasin

    2016-09-01

    Extreme ultraviolet interference lithography (EUV-IL, λ = 13.5 nm) has been shown to be a powerful technique not only for academic, but also for industrial research and development of EUV materials due to its relative simplicity yet record high-resolution patterning capabilities. With EUV-IL, it is possible to pattern high-resolution periodic images to create highly ordered nanostructures that are difficult or time consuming to pattern by electron beam lithography (EBL) yet interesting for a wide range of applications such as catalysis, electronic and photonic devices, and fundamental materials analysis, among others. Here, we will show state-of the-art research performed using the EUV-IL tool at the Swiss Light Source (SLS) synchrotron facility in the Paul Scherrer Institute (PSI). For example, using a grating period doubling method, a diffraction mask capable of patterning a world record in photolithography of 6 nm half-pitch (HP), was produced. In addition to the description of the method, we will give a few examples of applications of the technique. Well-ordered arrays of suspended silicon nanowires down to 6.5 nm linewidths have been fabricated and are to be studied as field effect transistors (FETs) or biosensors, for instance. EUV achromatic Talbot lithography (ATL), another interference scheme that utilizes a single grating, was shown to yield well-defined nanoparticles over large-areas with high uniformity presenting great opportunities in the field of nanocatalysis. EUV-IL is in addition, playing a key role in the future introduction of EUV lithography into high volume manufacturing (HVM) of semiconductor devices for the 7 and 5 nm logic node (16 nm and 13 nm HP, respectively) and beyond while the availability of commercial EUV-tools is still very much limited for research.

  12. Reusable platform concepts

    International Nuclear Information System (INIS)

    Gudmestad, O.T.; Sparby, B.K.; Stead, B.L.

    1993-01-01

    There is an increasing need to reduce costs of offshore production facilities in order to make development of offshore fields profitable. For small fields with short production time there is in particular a need to investigate ways to reduce costs. The idea of platform reuse is for such fields particularly attractive. This paper will review reusable platform concepts and will discuss their range of application. Particular emphasis will be placed on technical limitations. Traditional concepts as jackups and floating production facilities will be discussed by major attention will be given to newly developed ideas for reuse of steel jackets and concrete structures. It will be shown how the operator for several fields can obtain considerable savings by applying such reusable platform concepts

  13. Wireless sensor platform

    Science.gov (United States)

    Joshi, Pooran C.; Killough, Stephen M.; Kuruganti, Phani Teja

    2017-08-08

    A wireless sensor platform and methods of manufacture are provided. The platform involves providing a plurality of wireless sensors, where each of the sensors is fabricated on flexible substrates using printing techniques and low temperature curing. Each of the sensors can include planar sensor elements and planar antennas defined using the printing and curing. Further, each of the sensors can include a communications system configured to encode the data from the sensors into a spread spectrum code sequence that is transmitted to a central computer(s) for use in monitoring an area associated with the sensors.

  14. Windows Azure Platform

    CERN Document Server

    Redkar, Tejaswi

    2010-01-01

    The Azure Services Platform is a brand-new cloud-computing technology from Microsoft. It is composed of four core components-Windows Azure, .NET Services, SQL Services, and Live Services-each with a unique role in the functioning of your cloud service. It is the goal of this book to show you how to use these components, both separately and together, to build flawless cloud services. At its heart Windows Azure Platform is a down-to-earth, code-centric book. This book aims to show you precisely how the components are employed and to demonstrate the techniques and best practices you need to know

  15. Windows Azure Platform

    CERN Document Server

    Redkar, Tejaswi

    2011-01-01

    The Windows Azure Platform has rapidly established itself as one of the most sophisticated cloud computing platforms available. With Microsoft working to continually update their product and keep it at the cutting edge, the future looks bright - if you have the skills to harness it. In particular, new features such as remote desktop access, dynamic content caching and secure content delivery using SSL make the latest version of Azure a more powerful solution than ever before. It's widely agreed that cloud computing has produced a paradigm shift in traditional architectural concepts by providin

  16. Work Engagement: A Double-Edged Sword? A Study of the Relationship between Work Engagement and the Work-Home Interaction Using the ARK Research Platform

    Directory of Open Access Journals (Sweden)

    Katrine Listau

    2017-07-01

    Full Text Available The aim of the present study was to investigate how being engaged at work affects academics’ work-home interaction. Using the Conservation of Resources theory as a theoretical framework, the study contributes to existing research by examining the relationship between the work engagement subscales (i.e. vigour, dedication, and absorption and both work-home facilitation and work-home conflict. In order to test the hypotheses, a Partial Least Squares-Structural Equation Modelling analysis was conducted using a large sample of academics from the Norwegian university sector (N = 4378. The results indicated that vigour and dedication had a positive relationship with work-home facilitation and a negative relationship with work-home conflict. In contrast, absorption was not significantly related to work-home facilitation, but was positively associated with work-home conflict. Thus, we conclude that work engagement seems to have the potential to create both positive and negative outcomes.

  17. Impact of product platforms on lean production systems : evidence from industrial machinery manufacturing

    NARCIS (Netherlands)

    Alblas, A.A.; Wortmann, J.C.

    2012-01-01

    The present study describes the effects of product platform changes on lean production systems. Current research into product platforms focuses mostly on the development stage. However, although the initial development of platforms is an important issue, product platforms often evolve during later

  18. Stereotactic Body Radiation Therapy Delivery in a Genetically Engineered Mouse Model of Lung Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Du, Shisuo; Lockamy, Virginia [Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania (United States); Zhou, Lin [Department of Thoracic Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan (China); Xue, Christine; LeBlanc, Justin [Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania (United States); Glenn, Shonna [Xstrahl, Inc, Suwanee, Georgia (United States); Shukla, Gaurav; Yu, Yan; Dicker, Adam P.; Leeper, Dennis B. [Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania (United States); Lu, You [Department of Thoracic Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan (China); Lu, Bo, E-mail: bo.lu@jefferson.edu [Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania (United States)

    2016-11-01

    Purpose: To implement clinical stereotactic body radiation therapy (SBRT) using a small animal radiation research platform (SARRP) in a genetically engineered mouse model of lung cancer. Methods and Materials: A murine model of multinodular Kras-driven spontaneous lung tumors was used for this study. High-resolution cone beam computed tomography (CBCT) imaging was used to identify and target peripheral tumor nodules, whereas off-target lung nodules in the contralateral lung were used as a nonirradiated control. CBCT imaging helps localize tumors, facilitate high-precision irradiation, and monitor tumor growth. SBRT planning, prescription dose, and dose limits to normal tissue followed the guidelines set by RTOG protocols. Pathologic changes in the irradiated tumors were investigated using immunohistochemistry. Results: The image guided radiation delivery using the SARRP system effectively localized and treated lung cancer with precision in a genetically engineered mouse model of lung cancer. Immunohistochemical data confirmed the precise delivery of SBRT to the targeted lung nodules. The 60 Gy delivered in 3 weekly fractions markedly reduced the proliferation index, Ki-67, and increased apoptosis per staining for cleaved caspase-3 in irradiated lung nodules. Conclusions: It is feasible to use the SARRP platform to perform dosimetric planning and delivery of SBRT in mice with lung cancer. This allows for preclinical studies that provide a rationale for clinical trials involving SBRT, especially when combined with immunotherapeutics.

  19. The Canadian Urban Environmental Health Research Consortium - a protocol for building a national environmental exposure data platform for integrated analyses of urban form and health.

    Science.gov (United States)

    Brook, Jeffrey R; Setton, Eleanor M; Seed, Evan; Shooshtari, Mahdi; Doiron, Dany

    2018-01-08

    Multiple external environmental exposures related to residential location and urban form including, air pollutants, noise, greenness, and walkability have been linked to health impacts or benefits. The Canadian Urban Environmental Health Research Consortium (CANUE) was established to facilitate the linkage of extensive geospatial exposure data to existing Canadian cohorts and administrative health data holdings. We hypothesize that this linkage will enable investigators to test a variety of their own hypotheses related to the interdependent associations of built environment features with diverse health outcomes encompassed by the cohorts and administrative data. We developed a protocol for compiling measures of built environment features that quantify exposure; vary spatially on the urban and suburban scale; and can be modified through changes in policy or individual behaviour to benefit health. These measures fall into six domains: air quality, noise, greenness, weather/climate, and transportation and neighbourhood factors; and will be indexed to six-digit postal codes to facilitate merging with health databases. Initial efforts focus on existing data and include estimates of air pollutants, greenness, temperature extremes, and neighbourhood walkability and socioeconomic characteristics. Key gaps will be addressed for noise exposure, with a new national model being developed, and for transportation-related exposures, with detailed estimates of truck volumes and diesel emissions now underway in selected cities. Improvements to existing exposure estimates are planned, primarily by increasing temporal and/or spatial resolution given new satellite-based sensors and more detailed national air quality modelling. Novel metrics are also planned for walkability and food environments, green space access and function and life-long climate-related exposures based on local climate zones. Critical challenges exist, for example, the quantity and quality of input data to many of

  20. Creative Platform Learning (CPL)

    DEFF Research Database (Denmark)

    Christensen, Jonna Langeland; Hansen, Søren

    Creative Platform Learning (CPL) er en pædagogisk metode, der skaber foretagsomme og innovative elever, der kan anvende deres kreativitet til at lære nyt. Ifølge den nye skolereform skal Innovation og entreprenørskab tydeliggøres i alle fag. I CPL er det en integreret del af undervisningen...

  1. Games and Platform Decisions

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Mikkola, Juliana Hsuan

    2007-01-01

    is the application of on-line games in order to provide training for decision makers and in order to generate overview over the implications of platform decisions. However, games have to be placed in a context with other methods and we argue that a mixture of games, workshops, and simulations can provide improved...

  2. Shot loading platform analysis

    International Nuclear Information System (INIS)

    Norman, B.F.

    1994-01-01

    This document provides the wind/seismic analysis and evaluation for the shot loading platform. Hand calculations were used for the analysis. AISC and UBC load factors were used in this evaluation. The results show that the actual loads are under the allowable loads and all requirements are met

  3. Brake for rollable platform

    Science.gov (United States)

    Morris, A. L.

    1974-01-01

    Frame-mounted brake is independent of wheels and consists of simple lever-actuated foot. Brake makes good contact with surface even though foot pad is at higher or lower level than wheels, this is particularly important when a rollable platform is used on irregular surface.

  4. Multiyear Plan for Validation of EnergyPlus Multi-Zone HVAC System Modeling using ORNL's Flexible Research Platform

    Energy Technology Data Exchange (ETDEWEB)

    Im, Piljae [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Bhandari, Mahabir S. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); New, Joshua Ryan [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-10-01

    This document describes the Oak Ridge National Laboratory (ORNL) multiyear experimental plan for validation and uncertainty characterization of whole-building energy simulation for a multi-zone research facility using a traditional rooftop unit (RTU) as a baseline heating, ventilating, and air conditioning (HVAC) system. The project’s overarching objective is to increase the accuracy of energy simulation tools by enabling empirical validation of key inputs and algorithms. Doing so is required to inform the design of increasingly integrated building systems and to enable accountability for performance gaps between design and operation of a building. The project will produce documented data sets that can be used to validate key functionality in different energy simulation tools and to identify errors and inadequate assumptions in simulation engines so that developers can correct them. ASHRAE Standard 140, Method of Test for the Evaluation of Building Energy Analysis Computer Programs (ASHRAE 2004), currently consists primarily of tests to compare different simulation programs with one another. This project will generate sets of measured data to enable empirical validation, incorporate these test data sets in an extended version of Standard 140, and apply these tests to the Department of Energy’s (DOE) EnergyPlus software (EnergyPlus 2016) to initiate the correction of any significant deficiencies. The fitness-for-purpose of the key algorithms in EnergyPlus will be established and demonstrated, and vendors of other simulation programs will be able to demonstrate the validity of their products. The data set will be equally applicable to validation of other simulation engines as well.

  5. Cross-platform learning: on the nature of children's learning from multiple media platforms.

    Science.gov (United States)

    Fisch, Shalom M

    2013-01-01

    It is increasingly common for an educational media project to span several media platforms (e.g., TV, Web, hands-on materials), assuming that the benefits of learning from multiple media extend beyond those gained from one medium alone. Yet research typically has investigated learning from a single medium in isolation. This paper reviews several recent studies to explore cross-platform learning (i.e., learning from combined use of multiple media platforms) and how such learning compares to learning from one medium. The paper discusses unique benefits of cross-platform learning, a theoretical mechanism to explain how these benefits might arise, and questions for future research in this emerging field. Copyright © 2013 Wiley Periodicals, Inc., A Wiley Company.

  6. Mobile Platforms and Development Environments

    CERN Document Server

    Helal, Sumi; Li, Wengdong

    2012-01-01

    Mobile platform development has lately become a technological war zone with extremely dynamic and fluid movement, especially in the smart phone and tablet market space. This Synthesis lecture is a guide to the latest developments of the key mobile platforms that are shaping the mobile platform industry. The book covers the three currently dominant native platforms -- iOS, Android and Windows Phone -- along with the device-agnostic HTML5 mobile web platform. The lecture also covers location-based services (LBS) which can be considered as a platform in its own right. The lecture utilizes a sampl

  7. Changing the paradigm for marine data production, dissemination and validation with Collaborative Platforms. The GlobColour webservice, a prime example which leads to the integration of CWE technologies to build-up virtual research centres.

    Science.gov (United States)

    Fanton d'Andon, Odile; Martin-Lauzer, François-Regis; Mangin, Antoine; Barrot, Gilbert; Clouaire, Stephane; Sardou, Olivier; Demaria, Julien; Serra, Romain

    2015-04-01

    The GlobColour webservice provides a rich dataset of marine bio-geochemical information for research and education purposes. We report on recent evolutions to improve the functionalities of the service to access EO and in-situ data and check information quality. In addition, a new concept, the Collaborative Platform, support the processing of bespoke information for remote users. At the root of the service is an integrated and automated production chain, processing not only EO satellite data but also in-situ measurements from bio-Argo floats. This production chain provides daily updated bio-geochemical data and performs automated data analysis (merging of sensors, temporal and spatial binning). The GlobColour webservice has been recently upgraded to provide improved navigation and selection capabilities. These evolutions were necessary as the catalogue of EO products has been significantly increased, with many new parameters, new spatial resolution (1 km over Europe in addition to 4 km global products) and projections (rectangular grid in addition to sinus grid). The validation and quality control of the information is essential to demonstrate the fitness-for-purpose of the service. Match-ups between in-situ measurements and EO data are a key element to establish the validity of the information. The standard approach is to perform these match-ups off-line using a database of in-situ measurements, and report the results in a validation document. Two innovations are introduced which greatly increase the value for the user: • An interactive navigation tool allows a detailed analysis the results of the match-ups, with temporal and geographical selection capabilities. Background information for each match-up can be easily retrieved, both for in-situ (measurement identification) and for satellite data (context retrieval, providing information such as cloud coverage and spatial variability). This allows users to get a better insight into the validity of the retrieved

  8. Contrasting platform thinking and product modularization

    DEFF Research Database (Denmark)

    Boer, Henrike Engele Elisabeth; Persson, Magnus

    2015-01-01

    Product modularization and platform thinking are both practices that seek to alleviate the negative impact of product customization and variety on internal operations by relying on economies of substitution. Through the use of a standardized pool of components and interfaces, these practices aim...... to create a broad spectrum of product choices. At first sight, product modularization and platform thinking are very similar. The difference between these practices can, however, be found in the manner in which they employ standardization. Where product modularization focuses on creating standardized...... variants. There is a general lack of research addressing the contingency factors that dictate the appropriateness of the use of product modularization and platform thinking in different contexts. To our knowledge, no large-scale empirical research has been reported in which the two concepts, contextual...

  9. Available: motorised platform

    CERN Multimedia

    The COMPASS collaboration

    2014-01-01

    The COMPASS collaboration would like to offer to a new owner the following useful and fully operational piece of equipment, which is due to be replaced with better adapted equipment.   Please contact Erwin Bielert (erwin.bielert@cern.ch or 160539) for further information.  Motorized platform (FOR FREE):   Fabricated by ACL (Alfredo Cardoso & Cia Ltd) in Portugal. The model number is MeXs 5-­‐30.  Specifications: 5 m wide, 1 m deep, adjustable height (1.5 m if folded). Maximum working floor height: 4 m. conforms to CERN regulations, number LV158. Type LD500, capacity 500 kg and weight 2000 kg.  If no interested party is found before December 2014, the platform will be thrown away.

  10. RemoteLabs Platform

    Directory of Open Access Journals (Sweden)

    Nils Crabeel

    2012-03-01

    Full Text Available This paper reports on a first step towards the implementation of a framework for remote experimentation of electric machines – the RemoteLabs platform. This project was focused on the development of two main modules: the user Web-based and the electric machines interfaces. The Web application provides the user with a front-end and interacts with the back-end – the user and experiment persistent data. The electric machines interface is implemented as a distributed client server application where the clients, launched by the Web application, interact with the server modules located in platforms physically connected the electric machines drives. Users can register and authenticate, schedule, specify and run experiments and obtain results in the form of CSV, XML and PDF files. These functionalities were successfully tested with real data, but still without including the electric machines. This inclusion is part of another project scheduled to start soon.

  11. Common tester platform concept.

    Energy Technology Data Exchange (ETDEWEB)

    Hurst, Michael James

    2008-05-01

    This report summarizes the results of a case study on the doctrine of a common tester platform, a concept of a standardized platform that can be applicable across the broad spectrum of testing requirements throughout the various stages of a weapons program, as well as across the various weapons programs. The common tester concept strives to define an affordable, next-generation design that will meet testing requirements with the flexibility to grow and expand; supporting the initial development stages of a weapons program through to the final production and surveillance stages. This report discusses a concept investing key leveraging technologies and operational concepts combined with prototype tester-development experiences and practical lessons learned gleaned from past weapons programs.

  12. Online stock trading platform

    Directory of Open Access Journals (Sweden)

    Ion LUNGU

    2006-01-01

    Full Text Available The Internet is the perfect tool that can assure the market’s transparency for any user who wants to trade on the stock market. The investor can have access to the market news, financial calendar or the press releases of the issuers. A good online trading platform also provides real-time intraday quotes, trading history and technical analysis giving the investor a clearer view of the supply and demand in the market. All this information provides the investor a good image of the market and encourages him to trade. This paper wishes to draft the pieces of an online trading platform and to analyze the impact of developing and implementing one in a brokerage firm.

  13. Influence of the type of crude oil to platforming effects

    International Nuclear Information System (INIS)

    Kafedzhiski, Branko; Crvenkova, Suzana; Zikovski, Toni

    1999-01-01

    Platforming in one of the most subtleties processing in refinery industry and it is permanent source for research and finding out the higher optimum degree. Optimum of the last effects of platforming directly depends on many parameters. One of more important parameters is the type of crude. The purpose of this work is presenting positive and negative effect to the platforming parameters caused by different types of crude in OCTA-Crude Oil Refinery -Skopje, Macedonia. (Original)

  14. Influence of the crude oil type to platforming effects

    International Nuclear Information System (INIS)

    Kafedzhiski, Branko; Crvenkova, Suzana; Zikovski, Toni

    1999-01-01

    Platforming is one of the most subtleties processing in refinery industry and it is permanent source for research and finding out the higher optimum degree. Optimum of the last effects of platforming directly depends on many parameters. One of the more important parameters is the type of the crude. The purpose of this work is presenting positive and negative effect to the platforming parameters caused by different types of crude in OCTA Crude Oil Refinery - Skopje (Macedonia). (Author)

  15. SU-C-303-04: Evaluation of On- and Off-Line Bioluminescence Tomography System for Focal Irradiation Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, B; Wang, K; Reyes, J; Tran, P; Wong, J [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, MD (United States); Iordachita, I [Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD (United States)

    2015-06-15

    Purpose: We have developed offline and on-board bioluminescence tomography(BLT) systems for the small animal radiation research platform(SARRP) for radiation guidance of soft tissue targets. We investigated the effectiveness of offline BLT guidance. Methods: CBCT is equipped on both the offline BLT system and SARRP that are 10 ft. apart. To evaluate the setup error during animal transport between the two systems, we implanted a luminescence source in the abdomen of anesthetized mice. Five mice were studied. After CBCT was acquired on both systems, source centers and correlation coefficients were calculated. CBCT was also used to generate object mesh for BLT reconstruction. To assess target localization, we compared the localization of the luminescence source based on (1)on-board SARRP BLT and CBCT, (2)offline BLT and CBCT, and (3)offline BLT and SARRP CBCT. The 3rd comparison examines if an offline BLT system can be used to guide radiation when there is minimal target contrast in CBCT. Results: Our CBCT results show the offset of the light source center can be maintained within 0.2 mm during animal transport. The center of mass(CoM) of the light source reconstructed by the offline BLT has an offset of 1.0 ± 0.4 mm from the ‘true’ CoM as derived from the SARRP CBCT. The results compare well with the offset of 1.0 ± 0.2 mm using on-line BLT. Conclusion: With CBCT information provided by the SARRP and effective animal immobilization during transport, these findings support the use of offline BLT in close vicinity for accurate soft tissue target localization for irradiation. However, the disadvantage of the off-line system is reduced efficiency as care is required to maintain stable animal transport. We envisage a dual use system where the on-board arrangement allows convenient access to CBCT and avoids disturbance of animal setup. The off-line capability would support standalone longitudinal imaging studies. The work is supported by NIH R01CA158100 and Xstrahl

  16. HPC - Platforms Penta Chart

    Energy Technology Data Exchange (ETDEWEB)

    Trujillo, Angelina Michelle [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-10-08

    Strategy, Planning, Acquiring- very large scale computing platforms come and go and planning for immensely scalable machines often precedes actual procurement by 3 years. Procurement can be another year or more. Integration- After Acquisition, machines must be integrated into the computing environments at LANL. Connection to scalable storage via large scale storage networking, assuring correct and secure operations. Management and Utilization – Ongoing operations, maintenance, and trouble shooting of the hardware and systems software at massive scale is required.

  17. Cloud Robotics Platforms

    Directory of Open Access Journals (Sweden)

    Busra Koken

    2015-01-01

    Full Text Available Cloud robotics is a rapidly evolving field that allows robots to offload computation-intensive and storage-intensive jobs into the cloud. Robots are limited in terms of computational capacity, memory and storage. Cloud provides unlimited computation power, memory, storage and especially collaboration opportunity. Cloud-enabled robots are divided into two categories as standalone and networked robots. This article surveys cloud robotic platforms, standalone and networked robotic works such as grasping, simultaneous localization and mapping (SLAM and monitoring.

  18. Research

    African Journals Online (AJOL)

    in this study bases its professional competencies[5] (Table 1, left column) on ... available literature reports that international students are typically exposed ... [10] Furthermore, the transition period in a foreign country is ... platform to grow as person and as a ... NOMA students' own accounts of their experiences of the module.

  19. Learning Management Platform for CyberCIEGE

    Science.gov (United States)

    2011-12-01

    CLE is a platform that allows academic and research collaboration and it is built on open pedagogy and open standard [16]. In those situations...C. Irvine, “Active learning with the CyberCIEGE video game,” in Proceedings of the 4th Conference on Cyber Security Experimentation and Test, 2011

  20. Platform decommissioning. Environmental challenges and practical solutions

    International Nuclear Information System (INIS)

    Kvalvik, Inge

    1998-01-01

    The publication gives a short introduction of platform decommissioning, followed by an overview of what to be decommissioned and removed. This will be followed by some of the vital technologies and methods within decommissioning, abandonment of wells, removal and handling of remains that is reuse and scrapping. A final presentation with a view of current research and developments is given. 3 figs

  1. Colloidal nanophotonics: the emerging technology platform.

    Science.gov (United States)

    Gaponenko, Sergey; Demir, Hilmi Volkan; Seassal, Christian; Woggon, Ulrike

    2016-01-25

    Dating back to decades or even centuries ago, colloidal nanophotonics during the last ten years rapidly extends towards light emitting devices, lasers, sensors and photonic circuitry to manifest itself as an emerging technology platform rather than an entirely academic research field.

  2. A comparative study of cognitive radio platforms

    CSIR Research Space (South Africa)

    Masonta, MT

    2012-10-01

    Full Text Available -life deployments of CR systems, the research community is now focusing on the development of CR platforms. With different software defined radio (SDR) packages and hardware available, it is confusing to decide which one to build or use. The objective of this paper...

  3. Autonomous Landing on Moving Platforms

    KAUST Repository

    Mendoza Chavez, Gilberto

    2016-08-01

    This thesis investigates autonomous landing of a micro air vehicle (MAV) on a nonstationary ground platform. Unmanned aerial vehicles (UAVs) and micro air vehicles (MAVs) are becoming every day more ubiquitous. Nonetheless, many applications still require specialized human pilots or supervisors. Current research is focusing on augmenting the scope of tasks that these vehicles are able to accomplish autonomously. Precise autonomous landing on moving platforms is essential for self-deployment and recovery of MAVs, but it remains a challenging task for both autonomous and piloted vehicles. Model Predictive Control (MPC) is a widely used and effective scheme to control constrained systems. One of its variants, output-feedback tube-based MPC, ensures robust stability for systems with bounded disturbances under system state reconstruction. This thesis proposes a MAV control strategy based on this variant of MPC to perform rapid and precise autonomous landing on moving targets whose nominal (uncommitted) trajectory and velocity are slowly varying. The proposed approach is demonstrated on an experimental setup.

  4. Utilizing platforms in industrialized construction

    DEFF Research Database (Denmark)

    Bonev, Martin; Wörösch, Michael; Hvam, Lars

    2015-01-01

    platform strategies, this researchhighlights key aspects of adapting platform-based developed theory to industrialised construction.Building projects use different layers of product, process and logistics platforms to form the right cost– value ratio for the target market application, while modelling...

  5. Unraveling Platform Strategies: A Review from an Organizational Ambidexterity Perspective

    Directory of Open Access Journals (Sweden)

    Xing Wan

    2017-05-01

    Full Text Available Platform strategies, which highlight the interdependence in and evolution of business ecosystems, are increasingly relevant for sustainable business models in the digital era. So far, platform research has existed as a fragmented body of insights from different fields, but an integrated theoretical perspective can lead to a more coherent understanding of the research overall. Organizational ambidexterity emphasizes the balance between exploration and exploitation, which is particularly conducive to understanding the sustainability of a firm. Using an organizational ambidexterity perspective, the authors analyze five platform strategies: pricing, openness, integration, differentiation, and envelopment. This paper provides a systematic review of the theoretical and empirical studies in leading management, economics, and information systems journals from 2000 to 2016. The findings show that platform strategies can help platform owners achieve ambidexterity by domain, temporal, and organizational separation. Finally, this paper proposes an agenda for future research.

  6. Central American and Caribbean Citizen Security Platform | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Collaborative research platform This initiative will establish a real and virtual space known as the Central American and Caribbean Security Platform. It will bring together the region's scholars, practitioners, attorneys, journalists, and other stakeholders into regular, constructive dialogue with specialists dedicated to finding ...

  7. Platform thinking for services: the case of human resources

    NARCIS (Netherlands)

    Hofman, Erwin; Meijerink, Jeroen Gerard

    2015-01-01

    This paper tests the utility of platform thinking, a design principle that has so far been applied to product development yet under-researched in service settings, for improving the value of services. A key principle of platform thinking is to balance the reuse of service components with the

  8. Temperature profiles from XBT casts from the AMAGI MARU and other platforms from North Pacific Ocean by the Hokkaido Regional Fisheries Research Laboratory and other institutions from 1904-10-04 to 1985-12-31 (NODC Accession 9200262)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the AMAGI MARU and other platforms from 04 October 1904 to 31 December 1985. Data were collected by the...

  9. University technology platform of anticipatory learning

    Directory of Open Access Journals (Sweden)

    Leonid Davidovich Gitelman

    2016-03-01

    Full Text Available The innovative development sets large-scale and challenging tasks, which need to be addressed in the lack-of-knowledge conditions and require the coordination and integration of numerous expert structures, which are scattered around the world and have different status and competencies. One of the mechanisms of integrating the partners’ intellectual and financial resources is provided by the technology platforms. The article discusses the nature and functions of technology platforms and analyzes the experience of their application in different countries with a special emphasis on universities. The article gives an overview of the various interpretations of technology platform concepts. It also describes the development and implementation of the technological platform at the Ural Federal University (research and education centre ‘ENGEC’, which was targeted at organizing anticipatory learning in the sphere of energy engineering and high-tech industries; its mechanism and role in improving different university activities and processes are shown. This platform is based on the original methodology ‘Integrated System of Consulting, Training, and Transformation’ (ISCT, which includes authentic methods and technologies, which are used in the educational process. A significant advantage of this methodology is that it can be applied in university education as well as in corporate training integrated with innovative activities.

  10. A Virtual Commissioning Learning Platform

    DEFF Research Database (Denmark)

    Mortensen, Steffen; Madsen, Ole

    2018-01-01

    The introduction of reconfigurable manufacturing systems (RMS), Industry 4.0 and the associated technologies requires the establishment of new competencies. Towards that goal, Aalborg University (AAU) has developed an Industry 4.0 learning factory, the AAU Smart Production Lab. The AAU Smart...... Production Lab integrates a number of Industry 4.0 technologies for learning and research purposes. One of the many techniques is virtual commissioning. Virtual commissioning uses a virtual plant model and real controllers (PLCs) enabling a full emulation of the manufacturing system for verification. Virtual...... commissioning can lower the commissioning time up to 63%, allowing faster time to market. However, virtual commission is still missing industrial impact one of the reasons being lack of competencies and integration experiences. The paper presents the setup of the virtual commissioning learning platform...

  11. SERS sensors for DVD platform

    DEFF Research Database (Denmark)

    Brøgger, Anna Line

    This Ph.D. thesis explores the engineering of a portable sensor system for detection of rare and small molecules. The Ph.D. project is part of the research project 'Multi-Sensor DVD platform' (MUSE), aiming to integrate different sensors on a rotating disc. The sensors are chosen to complement each...... other, creating more reliable and stable results for the end user. The rotating disc comprises microfluidic channels, which can be utilized for handling and manipulating liquid samples such as blood or water. The focus of this Ph.D. thesis, is on the integration of one specific sensor on a rotating disc....... The sensor is based upon surface enhanced Raman spectroscopy (SERS), which detects molecular vibrations. The aim of this thesis is to cover the different aspects of the sensor system. SERS substrates, consisting of nanopillars with gold or silver caps on top, have been fabricated by standard micro and nano...

  12. Using Social Media as a Managerial Platform for an Educational Development Project : Cofimvaba

    CSIR Research Space (South Africa)

    Van der Vyver, AG

    2015-12-01

    Full Text Available of the project use Whatsapp, a popular social media platform to engage in managerial communication. The researchers found that this unconventional platform proved to be an excellent anchor for managerial communication on the project....

  13. Strategies Used by Professors through Virtual Educational Platforms in Face-to-Face Classes: A View from the Chamilo Platform

    Science.gov (United States)

    Valencia, Heriberto Gonzalez; Villota Enriquez, Jackeline Amparo; Agredo, Patricia Medina

    2017-01-01

    This study consisted in characterizing the strategies used by professors; implemented through virtual educational platforms. The context of this research were the classrooms of the Santiago de Cali University and the virtual space of the Chamilo virtual platform, where two professors from the Faculty of Education of the same university…

  14. The CERN Neutrino Platform

    CERN Document Server

    Bordoni, Stefania

    2018-01-01

    The long-baseline neutrino programme has been classified as one of the four highest-priority sci- entific objectives in 2013 by the European Strategy for Particle Physics. The Neutrino Platform is the CERN venture to foster and support the next generation of accelerator-based neutrino os- cillation experiments. Part of the present CERN Medium-Term Plan, the Neutrino Platform provide facilities to develop and prototype the next generation of neutrino detectors and contribute to unify the European neu- trino community towards the US and Japanese projects. A significative effort is made on R&D; for LAr TPC technologies: two big LAr TPC prototypes for the DUNE far detector are under con- struction at CERN. Those detectors will be exposed in 2018 to an entirely new and NP-dedicated beam-line from the SPS which will provide electron, muon and hadron beams with energies in the range of sub-GeV to a few GeV. Other projects are also presently under development: one can cite the refurbishing and shipping to the US ...

  15. Cloud Based Earth Observation Data Exploitation Platforms

    Science.gov (United States)

    Romeo, A.; Pinto, S.; Loekken, S.; Marin, A.

    2017-12-01

    and the Amazon Web Services cloud. This work will present an overview of the TEPs and the multi-cloud EO data processing platform, and discuss their main achievements and their impacts in the context of distributed Research Infrastructures such as EPOS and EOSC.

  16. Design for game based learning platforms

    DEFF Research Database (Denmark)

    Sørensen, Birgitte Holm; Meyer, Bente

    2010-01-01

    This paper focuses on the challenges related to the design of game based learning platforms for formal learning contexts that are inspired by the pupil's leisure time related use of web 2.0. The paper is based on the project Serious Games on a Global Market Place (2007-2011) founded by the Danish...... of web 2.0 and integrates theories of learning, didactics, games, play, communication, multimodality and different pedagogical approaches. In relation to the introduced model the teacher role is discussed.......This paper focuses on the challenges related to the design of game based learning platforms for formal learning contexts that are inspired by the pupil's leisure time related use of web 2.0. The paper is based on the project Serious Games on a Global Market Place (2007-2011) founded by the Danish...... Council for Strategic Research, in which an online game-based platform for English as a foreign language in primary school is studied. The paper presents a model for designing for game based learning platforms. This design is based on cultural and ethnographic based research on children's leisure time use...

  17. An Experimental Platform for Autonomous Bus Development

    Directory of Open Access Journals (Sweden)

    Héctor Montes

    2017-11-01

    Full Text Available Nowadays, with highly developed instrumentation, sensing and actuation technologies, it is possible to foresee an important advance in the field of autonomous and/or semi-autonomous transportation systems. Intelligent Transport Systems (ITS have been subjected to very active research for many years, and Bus Rapid Transit (BRT is one area of major interest. Among the most promising transport infrastructures, the articulated bus is an interesting, low cost, high occupancy capacity and friendly option. In this paper, an experimental platform for research on the automatic control of an articulated bus is presented. The aim of the platform is to allow full experimentation in real conditions for testing technological developments and control algorithms. The experimental platform consists of a mobile component (a commercial articulated bus fully instrumented and a ground test area composed of asphalt roads inside the Consejo Superior de Investigaciones Científicas (CSIC premises. This paper focuses also on the development of a human machine interface to ease progress in control system evaluation. Some experimental results are presented in order to show the potential of the proposed platform.

  18. PROBA-V Mission Exploitation Platform

    Directory of Open Access Journals (Sweden)

    Erwin Goor

    2016-07-01

    Full Text Available As an extension of the PROBA-Vegetation (PROBA-V user segment, the European Space Agency (ESA, de Vlaamse Instelling voor Technologisch Onderzoek (VITO, and partners TRASYS and Spacebel developed an operational Mission Exploitation Platform (MEP to drastically improve the exploitation of the PROBA-V Earth Observation (EO data archive, the archive from the historical SPOT-VEGETATION mission, and derived products by researchers, service providers, and thematic users. The analysis of the time series of data (petabyte range is addressed, as well as the large scale on-demand processing of the complete archive, including near real-time data. The platform consists of a private cloud environment, a Hadoop-based processing environment and a data manager. Several applications are released to the users, e.g., a full resolution viewing service, a time series viewer, pre-defined on-demand processing chains, and virtual machines with powerful tools and access to the data. After an initial release in January 2016 a research platform was deployed gradually, allowing users to design, debug, and test applications on the platform. From the PROBA-V MEP, access to, e.g., Sentinel-2 and Sentinel-3 data will be addressed as well.

  19. Preparing for a Product Platform

    DEFF Research Database (Denmark)

    Fiil-Nielsen, Ole; Munk, Lone; Mortensen, Niels Henrik

    2005-01-01

    on commonalities and similarities in the product family, and variance should be based on customer demands. To relate these terms and to improve the basis on which decisions are made, we need a way of visualizing the hierarchy of the product family as well as the commonality and variance. This visualization method...... of the platform or ensuring that the platform can meet future demands will be very useful in the preparation process of a platform synthesis as well as in the updating or reengineering of an existing product development platform.......Experience in the industry as well as recent related scientific publications show the benefits of product development platforms. Companies use platforms to develop not a single but multiple products (i.e. a product family) simultaneously. When these product development projects are coordinated...

  20. Adoption of Mobile Payment Platforms

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2016-01-01

    Numerous mobile payment solutions, which rely on new disruptive technologies, have been launched on the payment market in recent years. But despite the growing number of mobile payment apps, very few solutions have turned to be successful as the majority of them fail to gain a critical mass...... of users. In this paper, we investigate successful platform adoption strategies by using the Reach and Range Framework for Multi-Sided Platforms as a strategic tool to which mobile payment providers can adhere in order to tackle some of the main challenges they face throughout the evolution...... of their platforms. The analysis indicates that successful mobile payment solutions tend to be launched as one-sided platforms and then gradually be expanded into being two-sided. Our study showcases that the success of mobile payment platforms lies with the ability of the platform to balance the reach (number...

  1. Web Platform Application

    Energy Technology Data Exchange (ETDEWEB)

    Paulsworth, Ashley [Sunvestment Group, Frederick, MD (United States); Kurtz, Jim [Sunvestment Group, Frederick, MD (United States); Brun de Pontet, Stephanie [Sunvestment Group, Frederick, MD (United States)

    2016-06-15

    Sunvestment Energy Group (previously called Sunvestment Group) was established to create a web application that brings together site hosts, those who will obtain the energy from the solar array, with project developers and funders, including affinity investors. Sunvestment Energy Group (SEG) uses a community-based model that engages with investors who have some affinity with the site host organization. In addition to a financial return, these investors receive non-financial value from their investments and are therefore willing to offer lower cost capital. This enables the site host to enjoy more savings from solar through these less expensive Community Power Purchase Agreements (CPPAs). The purpose of this award was to develop an online platform to bring site hosts and investors together virtually.

  2. Mobile4D platform

    CSIR Research Space (South Africa)

    Botha, Adèle

    2010-05-01

    Full Text Available and share their own Internet/Telco service Mashups. digm. This all 2.1.2  SPICE   Service Platform for Innovative Communication Environment was also a European Union’s Sixth Framework Programme (FP6) funded project, which formed a consortium consisting...  OPUCE  SPICE  Twisted   Mobicents  Telco  specific  Minimal Total Life cycle cost  ?  ?  ?  ?  ?  Standards Compliant Solution  ?  ?  ?  ?  ?  Bearer & Device Agnostic  ?  ?  ?  ?  ?  Ease of use and accessibility  ?  ?  ?  ?  ?  Synergies...

  3. Energy Tracking Software Platform

    Energy Technology Data Exchange (ETDEWEB)

    Ryan Davis; Nathan Bird; Rebecca Birx; Hal Knowles

    2011-04-04

    Acceleration has created an interactive energy tracking and visualization platform that supports decreasing electric, water, and gas usage. Homeowners have access to tools that allow them to gauge their use and track progress toward a smaller energy footprint. Real estate agents have access to consumption data, allowing for sharing a comparison with potential home buyers. Home builders have the opportunity to compare their neighborhood's energy efficiency with competitors. Home energy raters have a tool for gauging the progress of their clients after efficiency changes. And, social groups are able to help encourage members to reduce their energy bills and help their environment. EnergyIT.com is the business umbrella for all energy tracking solutions and is designed to provide information about our energy tracking software and promote sales. CompareAndConserve.com (Gainesville-Green.com) helps homeowners conserve energy through education and competition. ToolsForTenants.com helps renters factor energy usage into their housing decisions.

  4. Sinking offshore platform. Nedsenkbar fralandsplatform

    Energy Technology Data Exchange (ETDEWEB)

    Einstabland, T.B.; Olsen, O.

    1988-12-19

    The invention deals with a sinking offshore platform of the gravitational type designed for being installed on the sea bed on great depths. The platform consists of at least three inclining pillars placed on a foundation unit. The pillars are at the upper end connected to a tower structure by means of a rigid construction. The tower supports the platform deck. The rigid construction comprises a centre-positioned cylinder connected to the foundation. 11 figs.

  5. Product Platform Screening at LEGO

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Steen Jensen, Thomas; Nielsen, Ole Fiil

    2012-01-01

    Product platforms offer great benefits to companies developing new products in highly competitive markets. Literature describes how a single platform can be designed from a technical point of view, but rarely mentions how the process begins. How do companies identify possible platform candidates...... after a few changes had been applied to the initial process layout. This case study shows how companies must focus on a limited selection of simultaneous projects in order to keep focus. Primary stakeholders must be involved from the very beginning, and short presentations of the platform concepts...

  6. Resilience of innovation platforms within armed conflicts: the case of ...

    African Journals Online (AJOL)

    . The Sub-Saharan Africa Challenge Program moved into the Province in 2008 and established four innovation platforms (IPs) under Integrated Agricultural Research for Development concepts, in Masisi and Rutshuru districts. The objective of ...

  7. Creating artificial reefs from decommissioned platforms in the North Sea: review of knowledge and proposed programme of research. Vol. 1 of a 2 vol. report. Summary of the main report, with an executive overview

    Energy Technology Data Exchange (ETDEWEB)

    Aabel, Jens Petter; Cripps, Simon; Jensen, Antony; Picken, Gordon

    1997-12-31

    In the continuing debate on the decommissioning and disposal of North Sea oil and gas platforms, the use of redundant structures as artificial reefs remains an untried possibility. It has been suggested that selected, clean, inert steel components could be used to create offshore reefs to attract finfish, to the benefit fisheries and fishermen. This might be an innovative and cost-effective use of these ``materials and opportunity``, and therefore should be examined more fully before the predicted 20-30 year period of steady decommissioning activity in the North Sea begins in earnest. This report relates on reviewing the use and effectiveness of artificial reefs, summarize existing knowledge of the reef effect of North Sea platforms, outline possible scenarios for the creation and exploitation of platform reefs in the North Sea, highlight gaps in knowledge, and to propose programmes of work to study the reef effect at an inshore and an offshore site in the North Sea. 5 tabs.

  8. Creating artificial reefs from decommissioned platforms in the North Sea: review of knowledge and proposed programme of research. Vol. 1 of a 2 vol. report. Summary of the main report, with an executive overview

    Energy Technology Data Exchange (ETDEWEB)

    Aabel, Jens Petter; Cripps, Simon; Jensen, Antony; Picken, Gordon

    1998-12-31

    In the continuing debate on the decommissioning and disposal of North Sea oil and gas platforms, the use of redundant structures as artificial reefs remains an untried possibility. It has been suggested that selected, clean, inert steel components could be used to create offshore reefs to attract finfish, to the benefit fisheries and fishermen. This might be an innovative and cost-effective use of these ``materials and opportunity``, and therefore should be examined more fully before the predicted 20-30 year period of steady decommissioning activity in the North Sea begins in earnest. This report relates on reviewing the use and effectiveness of artificial reefs, summarize existing knowledge of the reef effect of North Sea platforms, outline possible scenarios for the creation and exploitation of platform reefs in the North Sea, highlight gaps in knowledge, and to propose programmes of work to study the reef effect at an inshore and an offshore site in the North Sea. 5 tabs.

  9. Introducing Platform Interactions Model for Studying Multi-Sided Platforms

    DEFF Research Database (Denmark)

    Staykova, Kalina; Damsgaard, Jan

    2018-01-01

    Multi-Sided Platforms (MSPs) function as socio-technical entities that facilitate direct interactions between various affiliated to them constituencies through developing and managing IT architecture. In this paper, we aim to explain the nature of the platform interactions as key characteristic o...

  10. E-Sourcing platforms as reasonable marketing tools for suppliers

    OpenAIRE

    Göbl, Martin; Greiter, Thomas

    2014-01-01

    Research questions: E-sourcing platforms offer purchasing organisations often easy access to a high number of relevant suppliers, their goods and services and the accord-ing prices. For the suppliers, e-sourcing platforms are a good and easy pos-sibility to present their products and services to the relevant buyers and to get in contact with potential customers. Subject of this research will be the question, whether e-sourcing platforms are also a reasonable marketing tool for suppliers in or...

  11. Virtual interconnection platform initiative scoping study

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yong [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Kou, Gefei [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Pan, Zuohong [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Liu, Yilu [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); King Jr., Thomas J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-01-01

    Due to security and liability concerns, the research community has limited access to realistic large-scale power grid models to test and validate new operation and control methodologies. It is also difficult for industry to evaluate the relative value of competing new tools without a common platform for comparison. This report proposes to develop a large-scale virtual power grid model that retains basic features and represents future trends of major U.S. electric interconnections. This model will include realistic power flow and dynamics information as well as a relevant geospatial distribution of assets. This model will be made widely available to the research community for various power system stability and control studies and can be used as a common platform for comparing the efficacies of various new technologies.

  12. Development of a Decision Aid for Cardiopulmonary Resuscitation Involving Intensive Care Unit Patients' and Health Professionals' Participation Using User-Centered Design and a Wiki Platform for Rapid Prototyping: A Research Protocol

    Science.gov (United States)

    Heyland, Daren Keith; Ebell, Mark H; Dupuis, Audrey; Lavoie-Bérard, Carole-Anne; Légaré, France; Archambault, Patrick Michel

    2016-01-01

    Background Cardiopulmonary resuscitation (CPR) is an intervention used in cases of cardiac arrest to revive patients whose heart has stopped. Because cardiac arrest can have potentially devastating outcomes such as severe neurological deficits even if CPR is performed, patients must be involved in determining in advance if they want CPR in the case of an unexpected arrest. Shared decision making (SDM) facilitates discussions about goals of care regarding CPR in intensive care units (ICUs). Patient decision aids (DAs) are proven to support the implementation of SDM. Many patient DAs about CPR exist, but they are not universally implemented in ICUs in part due to lack of context and cultural adaptation. Adaptation to local context is an important phase of implementing any type of knowledge tool such as patient DAs. User-centered design supported by a wiki platform to perform rapid prototyping has previously been successful in creating knowledge tools adapted to the needs of patients and health professionals (eg, asthma action plans). This project aims to explore how user-centered design and a wiki platform can support the adaptation of an existing DA for CPR to the local context. Objective The primary objective is to use an existing DA about CPR to create a wiki-based DA that is adapted to the context of a single ICU and tailorable to individual patient’s risk factors while employing user-centered design. The secondary objective is to document the use of a wiki platform for the adaptation of patient DAs. Methods This study will be conducted in a mixed surgical and medical ICU at Hôtel-Dieu de Lévis, Quebec, Canada. We plan to involve all 5 intensivists and recruit at least 20 alert and oriented patients admitted to the ICU and their family members if available. In the first phase of this study, we will observe 3 weeks of daily interactions between patients, families, intensivists, and other allied health professionals. We will specifically observe 5 dyads of

  13. Cross-Platform Learning: On the Nature of Children's Learning from Multiple Media Platforms

    Science.gov (United States)

    Fisch, Shalom M.

    2013-01-01

    It is increasingly common for an educational media project to span several media platforms (e.g., TV, Web, hands-on materials), assuming that the benefits of learning from multiple media extend beyond those gained from one medium alone. Yet research typically has investigated learning from a single medium in isolation. This paper reviews several…

  14. A practice scaffolding interactive platform

    DEFF Research Database (Denmark)

    Bundsgaard, Jeppe

    2009-01-01

    A Practice Scaffolding Interactive Platform (PracSIP) is a social learning platform which supports students in collaborative project based learning by simulating a professional practice. A PracSIP puts the core tools of the simulated practice at the students' disposal, it organizes collaboration...

  15. OPEN INNOVATION PROCESSES IN SOCIAL MEDIA PLATFORMS

    OpenAIRE

    Yang, Yang

    2013-01-01

    Innovation power has becomes to the priority concern for many enterprises. Open innovation, which acts as a new innovation method, is now applied in many companies due to its unique advantages. On the other hand, social media platforms have been widely accepted by public and it shares an immeasurable business resources. Based on those facts, there must be space to link social media and open innovation together to achieve win-win. The objective was to research the important factors for op...

  16. Alternative Future Fleet Platform Architecture Study

    Science.gov (United States)

    2016-10-27

    accelerate fielding and the research and development required to develop next-generation capabilities. Adopting this more robust counter- surveillance...produced using steel vessel rules, which reduces resiliency but thus reduces costs. • Common Hull Auxiliary Multi-mission Platform (CHAMP): This...the ship would replace aging mission specific designs with a common hull to stabilize the industrial base, reduce life cycle costs and leverage

  17. Paper based electronics platform

    KAUST Repository

    Nassar, Joanna Mohammad

    2017-07-20

    A flexible and non-functionalized low cost paper-based electronic system platform fabricated from common paper, such as paper based sensors, and methods of producing paper based sensors, and methods of sensing using the paper based sensors are provided. A method of producing a paper based sensor can include the steps of: a) providing a conventional paper product to serve as a substrate for the sensor or as an active material for the sensor or both, the paper product not further treated or functionalized; and b) applying a sensing element to the paper substrate, the sensing element selected from the group consisting of a conductive material, the conductive material providing contacts and interconnects, sensitive material film that exhibits sensitivity to pH levels, a compressible and/or porous material disposed between a pair of opposed conductive elements, or a combination of two of more said sensing elements. The method of sensing can further include measuring, using the sensing element, a change in resistance, a change in voltage, a change in current, a change in capacitance, or a combination of any two or more thereof.

  18. Modal shapes optimization and feasibility analysis of NFAL platform

    Directory of Open Access Journals (Sweden)

    Bin WEI

    2017-08-01

    Full Text Available In order to avoid friction and scratching between the conveyor and the precision components when conveying object, an compact non-contact acoustic levitation prototype is designed, and the feasibility is theoretically and experimentally verified. The symmetry model is established through kinetic analysis with ANSYS. The modal and the coupled field computation at the central point of the transfer platform are simulated. The simulation results show that pure flexural or mixed flexural wave shapes appear with different wave numbers on the platform. Sweep frequency test is conducted on the compact platform prototype. The levitation experimental results confirm the feasibility of the ultrasound transfer process, the levitation frequency range and the mode of vibration. The theoretical and experimental results show that the optimal design of the modal and the carrying capacity of the driving platform is necessary according to different conditions. The research results provide a reference for the design of the mode and bandwidth of the ultrasonic levitation platform.

  19. Determination of current loads of floating platform for special purposes

    Science.gov (United States)

    Ma, Guang-ying; Yao, Yun-long; Zhao, Chen-yao

    2017-08-01

    This article studied a new floating offshore platform for special purposes, which was assembled by standard floating modules. The environmental load calculation of the platform is an important part of the research of the ocean platform, which has always been paid attention to by engineers. In addition to wave loads, the wind loads and current loads are also important environmental factors that affect the dynamic response of the offshore platform. The current loads on the bottom structure should not be ignored. By Fluent software, the hydrostatic conditions and external current loads of the platform were calculated in this paper. The coefficient which is independent of the current velocity, namely, current force coefficient, can be fitted through current loads, which can be used for the consequent hydrodynamic and mooring analyses.

  20. Experimental platforms for behavioral experiments on social-ecological systems

    Directory of Open Access Journals (Sweden)

    Marco A. Janssen

    2014-12-01

    Full Text Available Recently, there has been an increased interest in using behavioral experiments to study hypotheses on the governance of social-ecological systems. A diversity of software tools are used to implement such experiments. We evaluated various publicly available platforms that could be used in research and education on the governance of social-ecological systems. The aims of the various platforms are distinct, and this is noticeable in the differences in their user-friendliness and their adaptability to novel research questions. The more easily accessible platforms are useful for prototyping experiments and for educational purposes to illustrate theoretical concepts. To advance novel research aims, more elaborate programming experience is required to either implement an experiment from scratch or adjust existing experimental software. There is no ideal platform best suited for all possible use cases, but we have provided a menu of options and their associated trade-offs.

  1. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-03-02

    Mar 2, 2015 ... Joseph Daniels1,&, Ruth Nduati1,2, James Kiarie1,3, Carey Farquhar1,4,5 .... or basic science research career (Socio-Behavioral Research, .... a research environment that supports knowledge sharing to develop research ...

  2. Design and Development of Fire Gridding Platform Based on Internet of Things

    Directory of Open Access Journals (Sweden)

    Wei San-Xi

    2016-01-01

    Full Text Available This article describes the construction background about fire gridding platform, reviews the research and progress in fire Internet of Things and fire gridding. The platform includes perception / execution layer, field control layer, network layer, center platform layer and application layer, which provide a good bonding about site control and remote monitoring. This article supplies a detail design for the main functions of application and task flow of fire hazard investigation. At the same time, a digital management platform was developed.

  3. ICP (ITER Collaborative Platform)

    Energy Technology Data Exchange (ETDEWEB)

    Capuano, C.; Carayon, F.; Patel, V. [ITER, 13 - St. Paul-Lez Durance (France)

    2009-07-01

    The ITER organization has the necessity to manage a massive amount of data and processes. Each team requires different process and databases often interconnected with those of others teams. ICP is the current central ITER repository of structured and unstructured data. All data in ICP is served and managed via a web interface that provides global accessibility with a common user friendly interface. This paper will explain the model used by ICP and how it serves the ITER project by providing a robust and agile platform. ICP is developed in ASP.NET using MSSQL Server for data storage. It currently houses 15 data driven applications, 150 different types of record, 500 k objects and 2.5 M references. During European working hours the system averages 150 concurrent users and 20 requests per second. ICP connects to external database applications to provide a single entry point to ITER data and a safe shared storage place to maintain this data long-term. The Core model provides an easy to extend framework to meet the future needs of the Organization. ICP follows a multi-tier architecture, providing logical separation of process. The standard three-tier architecture is expanded, with the data layer separated into data storage, data structure, and data access components. The business or applications logic layer is broken up into a common business functionality layer, a type specific logic layer, and a detached work-flow layer. Finally the presentation tier comprises a presentation adapter layer and an interface layer. Each layer is built up from small blocks which can be combined to create a wide range of more complex functionality. Each new object type developed gains access to a wealth of existing code functionality, while also free to adapt and extend this. The hardware structure is designed to provide complete redundancy, high availability and to handle high load. This document is composed of an abstract followed by the presentation transparencies. (authors)

  4. Platform Expansion Design as Strategic Choice

    DEFF Research Database (Denmark)

    Staykova, Kalina S.; Damsgaard, Jan

    2016-01-01

    In this paper, we address how the strategic choice of platform expansion design impacts the subse-quent platform strategy. We identify two distinct approaches to platform expansion – platform bun-dling and platform constellations, which currently co-exist. The purpose of this paper is to outline...

  5. A Typology of Multi-sided Platforms

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2015-01-01

    In this paper we address how the composition of a platform impacts the platform’s business model. By platform’s business model we mean platform features, platform architecture and platform governance. To this end, we construct the Platform Business Model Framework. We apply the framework to three...

  6. Vertical Relationships within Platform Marketplaces

    Directory of Open Access Journals (Sweden)

    Mark J. Tremblay

    2016-07-01

    Full Text Available In two-sided markets a platform allows consumers and sellers to interact by creating sub-markets within the platform marketplace. For example, Amazon has sub-markets for all of the different product categories available on its site, and smartphones have sub-markets for different types of applications (gaming apps, weather apps, map apps, ridesharing apps, etc.. The network benefits between consumers and sellers depend on the mode of competition within the sub-markets: more competition between sellers lowers product prices, increases the surplus consumers receive from a sub-market, and makes platform membership more desirable for consumers. However, more competition also lowers profits for a seller which makes platform membership less desirable for a seller and reduces seller entry and the number of sub-markets available on the platform marketplace. This dynamic between seller competition within a sub-market and agents’ network benefits leads to platform pricing strategies, participation decisions by consumers and sellers, and welfare results that depend on the mode of competition. Thus, the sub-market structure is important when investigating platform marketplaces.

  7. Particle platforms for cancer immunotherapy

    Directory of Open Access Journals (Sweden)

    Serda RE

    2013-04-01

    Full Text Available Rita Elena Serda Department of Nanomedicine, The Methodist Hospital Research Institute, Houston, TX, USA Abstract: Elevated understanding and respect for the relevance of the immune system in cancer development and therapy has led to increased development of immunotherapeutic regimens that target existing cancer cells and provide long-term immune surveillance and protection from cancer recurrence. This review discusses using particles as immune adjuvants to create vaccines and to augment the anticancer effects of conventional chemotherapeutics. Several particle prototypes are presented, including liposomes, polymer nanoparticles, and porous silicon microparticles, the latter existing as either single- or multiparticle platforms. The benefits of using particles include immune-cell targeting, codelivery of antigens and immunomodulatory agents, and sustained release of the therapeutic payload. Nanotherapeutic-based activation of the immune system is dependent on both intrinsic particle characteristics and on the immunomodulatory cargo, which may include danger signals known as pathogen-associated molecular patterns and cytokines for effector-cell activation. Keywords: adjuvant, particle, immunotherapy, dendritic cell, cancer, vaccine

  8. Research

    African Journals Online (AJOL)

    A descriptive qualitative research design was used to determine whether participants ... simulation as a teaching method; a manikin offering effective learning; confidence ..... Tesch R. Qualitative Research: Analysis Types and Software Tools.

  9. Platform decisions supported by gaming

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Mikkola, Juliana Hsuan

    2007-01-01

    Platform is an ambiguous multidisciplinary concept. The philosophy behind it is easy to communicate and makes intuitively sense. However, the ease in communication does overshadow the high complexity when the concept is implemented. The practical industrial platform implementation challenge can...... be described as being a configuration problem with a high number of variables. These variables are different in nature; they have contradictory influence on the total performance, and, their importance change over time. Consequently, the specific platform decisions become highly complex and the consequences...

  10. Research

    African Journals Online (AJOL)

    research process, as part of which students must find and appraise evidence from research.[5] This highlights that teaching research methodology is inclined towards equipping students ... Students believed that evidence-based practice was vital, yet their understanding of the concept was restricted when compared with the.

  11. Floating Ocean Platform

    Science.gov (United States)

    2003-08-15

    Proc ICOSSAR 89 5th Int Conf Struct Saf Reliab, 1989, p 183-190 Fukusumi, Tadahiro (Kobe Univ); Kusakabe, Kaoru , Dynamic response 162 characteristics...Harbor Research Institute, Ministry of Transport, Japan, October, 348--359, 1994 Maeda, N. and Morikawa, M. and Ishikawa , K. and Kakuta, Y., Fatigue...Harbor Research Institute, Ministry of Transport, Japan, October, 383--394, 1994 Morikawa, M. and Suzuki, H. and Ishikawa , K. and Komiya, H. and Yoshida

  12. Updating the Micro-Tom TILLING platform.

    Science.gov (United States)

    Okabe, Yoshihiro; Ariizumi, Tohru; Ezura, Hiroshi

    2013-03-01

    The dwarf tomato variety Micro-Tom is regarded as a model system for functional genomics studies in tomato. Various tomato genomic tools in the genetic background of Micro-Tom have been established, such as mutant collections, genome information and a metabolomic database. Recent advances in tomato genome sequencing have brought about a significant need for reverse genetics tools that are accessible to the larger community, because a great number of gene sequences have become available from public databases. To meet the requests from the tomato research community, we have developed the Micro-Tom Targeting-Induced Local Lesions IN Genomes (TILLING) platform, which is comprised of more than 5000 EMS-mutagenized lines. The platform serves as a reverse genetics tool for efficiently identifying mutant alleles in parallel with the development of Micro-Tom mutant collections. The combination of Micro-Tom mutant libraries and the TILLING approach enables researchers to accelerate the isolation of desirable mutants for unraveling gene function or breeding. To upgrade the genomic tool of Micro-Tom, the development of a new mutagenized population is underway. In this paper, the current status of the Micro-Tom TILLING platform and its future prospects are described.

  13. MycoCAP - Mycobacterium Comparative Analysis Platform.

    Science.gov (United States)

    Choo, Siew Woh; Ang, Mia Yang; Dutta, Avirup; Tan, Shi Yang; Siow, Cheuk Chuen; Heydari, Hamed; Mutha, Naresh V R; Wee, Wei Yee; Wong, Guat Jah

    2015-12-15

    Mycobacterium spp. are renowned for being the causative agent of diseases like leprosy, Buruli ulcer and tuberculosis in human beings. With more and more mycobacterial genomes being sequenced, any knowledge generated from comparative genomic analysis would provide better insights into the biology, evolution, phylogeny and pathogenicity of this genus, thus helping in better management of diseases caused by Mycobacterium spp.With this motivation, we constructed MycoCAP, a new comparative analysis platform dedicated to the important genus Mycobacterium. This platform currently provides information of 2108 genome sequences of at least 55 Mycobacterium spp. A number of intuitive web-based tools have been integrated in MycoCAP particularly for comparative analysis including the PGC tool for comparison between two genomes, PathoProT for comparing the virulence genes among the Mycobacterium strains and the SuperClassification tool for the phylogenic classification of the Mycobacterium strains and a specialized classification system for strains of Mycobacterium abscessus. We hope the broad range of functions and easy-to-use tools provided in MycoCAP makes it an invaluable analysis platform to speed up the research discovery on mycobacteria for researchers. Database URL: http://mycobacterium.um.edu.my.

  14. 媒体产业中的平台质量竞争——基于双边市场的理论视角的研究%Research on Platform Quality Competition in the Media Industry Based on Two-sided Market Theory

    Institute of Scientific and Technical Information of China (English)

    万兴

    2012-01-01

    The media industry is a typical two-sided market, where audiences and advertisers are the two sides. There are two typieal faets of the two-sided markets in the media industry. Firstly, the major revenue source of the same category media platform may differ. The feature is rare in other industries, where the make-money side is fixed. Secondly, the first-mover advantage in the media industry is not as remarkable as in other industries that are characterized by network effect. The first-mover advantage often brings entry barriers for a later comer, but the media industry witnesses many eases of successful market entry. How to analyze the difference in major revenue source, the traditional horizontal difference model or one-sided model cannot give reasonable explanation. The qual- ity difference of media contents is critical for a media platform to choose its business model. The paper establishes a two-sided market model including the quality factor to analyze the monopoly and duopoly situation. The paper has two contributions. Firstly, this paper incorporates quality into a two-sided model to analyze the quality choice of a platform on market performance. Secondly, this paper uses the quality-difference model to analyze whether or not there is the first-mover advantage in a two-sided media market and whether or not a latecomer can gain advantage over an incumbent. This paper establishes the two-sided model and makes discussion using the TV channel industry as an example. However, the modeling process and results are not limited to the industry but suitable for many media sectors. The research finds that a monopoly platform can make profits from the audience side with high content quality or depends on advertisement fees based on network externalities, but a strategy of tradeoff is not desirable. With the increase of network externalities between audiences and advertisers, the audience-side and advertiser-side profits both inerease. With the increase of eontent

  15. CLOUD BASED WEB 3D GIS TAIWAN PLATFORM

    Directory of Open Access Journals (Sweden)

    W.-F. Tsai

    2012-09-01

    Full Text Available This article presents the status of the web 3D GIS platform, which has been developed in the National Applied Research Laboratories. The purpose is to develop a global earth observation 3D GIS platform for applications to disaster monitoring and assessment in Taiwan. For quick response to preliminary and detailed assessment after a natural disaster occurs, the web 3D GIS platform is useful to access, transfer, integrate, display and analyze the multi-scale huge data following the international OGC standard. The framework of cloud service for data warehousing management and efficiency enhancement using VMWare is illustrated in this article.

  16. Perfect discipline platform and Promote interactive development

    Directory of Open Access Journals (Sweden)

    Xiang-ming ZENG

    2014-11-01

    Full Text Available Through the questionnaire survey of Marxism’s course construction and Ideological and Political Theory Course in 45 universities, the paper tries to discuss how to enhance the effectiveness of ideological and political theory course by platform of Marxism’s course construction. Research shows that it can enhance the effectiveness of Ideological and Political Theory Course as long as we make full use of platform construction of Marxism’s course, fully display the Marxism’s spirit with the times and the latest achievements in Ideological and political theory course, and Strengthen academic ideological and Political Theory Education. We believe that it can better cultivate socialist builders to achieve the Chinese dream by playing the educational function of Ideological and Political Theory Course.

  17. Smart Makerspace: A Web Platform Implementation

    Directory of Open Access Journals (Sweden)

    Gabriel Licks

    2018-02-01

    Full Text Available Makerspaces are creative and learning environments, home to activities such as fabrication processes and Do-It-Yourself (DIY tasks. However, containing equipment that are not commonly seen or handled, these spaces can look rather challenging to novice users. This paper is based on the Smart Makerspace research from Autodesk, which uses a smart workbench for an immersive instructional space for DIY tasks. Having its functionalities in mind and trying to overcome some of its limitations, we approach the concept building an immersive instructional space as a web platform. The platform, introduced to users in a makerspace, had a feedback that reflects its potential between novice and intermediate users, for creating facilitators and encouraging these users.

  18. Designing Polymeric Microfluidic Platforms for Biomedical Applications

    DEFF Research Database (Denmark)

    Vedarethinam, Indumathi

    Micro- and Nanotechnology have the potential to offer a smart solution for diagnostics and academia research with rapid, low cost, robust analysis systems to facilitate biological analyses. New, high throughput microfluidic platforms have the potential to surpass in performance the conventional...... analyses systems in use today. The overall goal of this PhD project is to address two different areas using microfluidics : i) Chromosome analysis by metaphase FISH such a platform, if successful, can immediately substitute the routine, labor-intensive, glass slide-based FISH analyses in Clinical...... Cytogenetics laboratories. During the course of this project, initially the suitability of the polymeric chip substrate was tested and a microfluidic device was developed for performing interphase FISH analysis. With this device, the key factors involved in chromosome spreading crucial to FISH analysis were...

  19. NASA Airborne Science Program: NASA Stratospheric Platforms

    Science.gov (United States)

    Curry, Robert E.

    2010-01-01

    The National Aeronautics and Space Administration conducts a wide variety of remote sensing projects using several unique aircraft platforms. These vehicles have been selected and modified to provide capabilities that are particularly important for geophysical research, in particular, routine access to very high altitudes, long range, long endurance, precise trajectory control, and the payload capacity to operate multiple, diverse instruments concurrently. While the NASA program has been in operation for over 30 years, new aircraft and technological advances that will expand the capabilities for airborne observation are continually being assessed and implemented. This presentation will review the current state of NASA's science platforms, recent improvements and new missions concepts as well as provide a survey of emerging technologies unmanned aerial vehicles for long duration observations (Global Hawk and Predator). Applications of information technology that allow more efficient use of flight time and the ability to rapidly reconfigure systems for different mission objectives are addressed.

  20. REVEAL: Software Documentation and Platform Migration

    Science.gov (United States)

    Wilson, Michael A.; Veibell, Victoir T.; Freudinger, Lawrence C.

    2008-01-01

    The Research Environment for Vehicle Embedded Analysis on Linux (REVEAL) is reconfigurable data acquisition software designed for network-distributed test and measurement applications. In development since 2001, it has been successfully demonstrated in support of a number of actual missions within NASA s Suborbital Science Program. Improvements to software configuration control were needed to properly support both an ongoing transition to operational status and continued evolution of REVEAL capabilities. For this reason the project described in this report targets REVEAL software source documentation and deployment of the software on a small set of hardware platforms different from what is currently used in the baseline system implementation. This report specifically describes the actions taken over a ten week period by two undergraduate student interns and serves as a final report for that internship. The topics discussed include: the documentation of REVEAL source code; the migration of REVEAL to other platforms; and an end-to-end field test that successfully validates the efforts.

  1. Technology review: prototyping platforms for monitoring ambient conditions.

    Science.gov (United States)

    Afolaranmi, Samuel Olaiya; Ramis Ferrer, Borja; Martinez Lastra, Jose Luis

    2018-05-08

    The monitoring of ambient conditions in indoor spaces is very essential owing to the amount of time spent indoors. Specifically, the monitoring of air quality is significant because contaminated air affects the health, comfort and productivity of occupants. This research work presents a technology review of prototyping platforms for monitoring ambient conditions in indoor spaces. It involves the research on sensors (for CO 2 , air quality and ambient conditions), IoT platforms, and novel and commercial prototyping platforms. The ultimate objective of this review is to enable the easy identification, selection and utilisation of the technologies best suited for monitoring ambient conditions in indoor spaces. Following the review, it is recommended to use metal oxide sensors, optical sensors and electrochemical sensors for IAQ monitoring (including NDIR sensors for CO 2 monitoring), Raspberry Pi for data processing, ZigBee and Wi-Fi for data communication, and ThingSpeak IoT platform for data storage, analysis and visualisation.

  2. IRET: requirements for service platforms

    OpenAIRE

    Baresi, Luciano; Ripa, Gianluca; Pasquale, Liliana

    2013-01-01

    peer-reviewed This paper describes IRENE (Indenica Requirements ElicitatioN mEthod), a methodology to elicit and model the requirements of service platforms, and IRET (IREne Tool), the Eclipse-based modeling framework we developed for IRENE

  3. Platform attitude data acquisition system

    Digital Repository Service at National Institute of Oceanography (India)

    Afzulpurkar, S.

    A system for automatic acquisition of underwater platform attitude data has been designed, developed and tested in the laboratory. This is a micro controller based system interfacing dual axis inclinometer, high-resolution digital compass...

  4. Microneedle Platforms for Cell Analysis

    KAUST Repository

    Kavaldzhiev, Mincho

    2017-01-01

    to the development of micro-needle platforms that offer customized fabrication and new capabilities for enhanced cell analyses. The highest degree of geometrical flexibility is achieved with 3D printed micro-needles, which enable optimizing the topographical stress

  5. Elevated Fixed Platform Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Elevated Fixed Platform (EFP) is a helicopter recovery test facility located at Lakehurst, NJ. It consists of a 60 by 85 foot steel and concrete deck built atop...

  6. Radiographic inspection on offshore platforms

    International Nuclear Information System (INIS)

    Soares, Sergio Damasceno; Sperandio, Augusto Gasparoni

    1994-01-01

    One of the great challenges for non-destructive inspection is on offshore platforms, where safety is a critical issue. Inspection by gammagraphy is practically forbidden on the platform deck due to problems to personnel safety and radiological protection. Ir-192 sources are used and the risk of an accident with loss of radioisotope must be considered. It is unfeasible to use gammagraphy, because in case of an accident the rapid evacuation from the platform would be impossible. This problem does not occur when X-ray equipment is used as the radiation source. The limited practicality and portability of the X-ray equipment have prevented its use as a replacement for the gammagraphy. This paper presents the preliminary tests to see the viable use of radiographic tests with constant potential on offshore platforms. (author). 2 refs., 1 fig., 2 tabs, 3 photos

  7. Miniaturized Spacecraft Platform for Command, Data Handling and Electronics, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Microelectronics Research Development Corporation (Micro RDC) proposes to develop a platform of low mass/volume/power, reliable miniaturized electronic modules that...

  8. CILogon: An Integrated Identity and Access Management Platform for Science

    Science.gov (United States)

    Basney, J.

    2016-12-01

    When scientists work together, they use web sites and other software to share their ideas and data. To ensure the integrity of their work, these systems require the scientists to log in and verify that they are part of the team working on a particular science problem. Too often, the identity and access verification process is a stumbling block for the scientists. Scientific research projects are forced to invest time and effort into developing and supporting Identity and Access Management (IAM) services, distracting them from the core goals of their research collaboration. CILogon provides an IAM platform that enables scientists to work together to meet their IAM needs more effectively so they can allocate more time and effort to their core mission of scientific research. The CILogon platform enables federated identity management and collaborative organization management. Federated identity management enables researchers to use their home organization identities to access cyberinfrastructure, rather than requiring yet another username and password to log on. Collaborative organization management enables research projects to define user groups for authorization to collaboration platforms (e.g., wikis, mailing lists, and domain applications). CILogon's IAM platform serves the unique needs of research collaborations, namely the need to dynamically form collaboration groups across organizations and countries, sharing access to data, instruments, compute clusters, and other resources to enable scientific discovery. CILogon provides a software-as-a-service platform to ease integration with cyberinfrastructure, while making all software components publicly available under open source licenses to enable re-use. Figure 1 illustrates the components and interfaces of this platform. CILogon has been operational since 2010 and has been used by over 7,000 researchers from more than 170 identity providers to access cyberinfrastructure including Globus, LIGO, Open Science Grid

  9. Bioma platform advancements during 2017

    OpenAIRE

    FUMAGALLI DAVIDE; NIEMEYER STEFAN

    2017-01-01

    In this report we describe the advancements on the Bioma Framework developed during year 2017. Given that the Bioma platform is quite mature, its core was not recently changed. So that the majority of changes concerns the implementation of the models developed in the platform. Moreover, during 2017 we also set up an alternative version of the framework itself, based on a new developing framework called .NET Core, with the purpose of being able to create a version of Bioma runnable on Linux. ...

  10. Using and Designing Platforms for In Vivo Education Experiments

    OpenAIRE

    Williams, Joseph Jay; Ostrow, Korinn; Xiong, Xiaolu; Glassman, Elena; Kim, Juho; Maldonado, Samuel G.; Li, Na; Reich, Justin; Hefferman, Neil

    2015-01-01

    In contrast to typical laboratory experiments, the everyday use of online educational resources by large populations and the prevalence of software infrastructure for A/B testing leads us to consider how platforms can embed in vivo experiments that do not merely support research, but ensure practical improvements to their educational components. Examples are presented of randomized experimental comparisons conducted by subsets of the authors in three widely used online educational platforms K...

  11. KYPO – A Platform for Cyber Defence Exercises

    OpenAIRE

    Čeleda Pavel; Čegan Jakub; Vykopal Jan; Tovarňák Daniel

    2015-01-01

    Correct and timely responses to cyber attacks are crucial for the effective implementation of cyber defence strategies and policies. The number of threats and ingenuity of attackers is ever growing, as is the need for more advanced detection tools, techniques and skilled cyber security professionals. KYPO – Cyber Exercise & Research Platform is focused on modelling and simulating complex computer systems and networks in a virtualized and separated environment. The platform enables realist...

  12. Users and Programmers Guide for HPC Platforms in CIEMAT

    International Nuclear Information System (INIS)

    Munoz Roldan, A.

    2003-01-01

    This Technical Report presents a description of the High Performance Computing platforms available to researchers in CIEMAT and dedicated mainly to scientific computing. It targets to users and programmers and tries to help in the processes of developing new code and porting code across platforms. A brief review is also presented about historical evolution in the field of HPC, ie, the programming paradigms and underlying architectures. (Author) 32 refs

  13. Research

    African Journals Online (AJOL)

    2014-05-06

    May 6, 2014 ... facilitate and support articulation between the ECT mid-level worker qualification and the professional B EMC degree. Methods. The researchers used an exploratory, sequential mixed-method design, which is characterised by a qualitative phase of research followed by a quantitative phase. This design is ...

  14. Research

    African Journals Online (AJOL)

    supports medical education and research at institutions in 12 ... (CBE). CapacityPlus, led by IntraHealth International, is the USAID-funded ... acquire public health, clinical, and/or research skills, usually through applied learning in a .... If students were evaluated, indicate the type of student (i.e. medical, dental, nursing, etc.) ...

  15. Research

    African Journals Online (AJOL)

    abp

    2017-01-24

    Jan 24, 2017 ... and the specific rotavirus VP4 (P-types) and VP7 (G-types) determined. Results: The .... Centre for Virus Research (CVR) of the Kenya Medical Research. Institute (KEMRI) ... rotavirus dsRNA was run on 10% polyacrylamide resolving gels using a large format .... What is known about this topic. •. Rotavirus is ...

  16. 基于区块链的第三代中药追溯平台构建研究%Research for Platform Construction of the Third Generation of Traceability for TCM Based on the Blockchain

    Institute of Scientific and Technical Information of China (English)

    温川飙; 赵姝婷; 陈菊; 施明毅; 高原

    2017-01-01

    本文回顾了中药追溯技术发展的8年历程,从基本架构、应用开发到开放平台的三个阶段,探讨中药追溯体系当前面临的主要技术问题和解决思路,重点阐述基于区块链技术的第三代中药追溯平台的开放共享架构原理和方法,讨论物联网、大数据、标准化和接口规范等关键技术对去中心化中药追溯平台构建的意义和作用,为新一代中药追溯体系提供建设思路.%This paper reviews the development of traceability technology for Traditional Chinese Medicine (TCM) backing 8 years,from the stage of the basic architecture,application development to the open platform,to explore the main technical problems of traceability system for TCM facing and solutions,focusing on the blockchain technology of the third-generation TCM traceability platform of open architecture based on the principle and method of sharing.Finally the paper discuss the key technologies,such as the Internet of things,big data,standardization and interface specification,make great significance and function to the construction of the decentralized traceability platform for TCM,which will provide the construction ideas for the new generation of traceability system for TCM.

  17. Geospatial Data Management Platform for Urban Groundwater

    Science.gov (United States)

    Gaitanaru, D.; Priceputu, A.; Gogu, C. R.

    2012-04-01

    Due to the large amount of civil work projects and research studies, large quantities of geo-data are produced for the urban environments. These data are usually redundant as well as they are spread in different institutions or private companies. Time consuming operations like data processing and information harmonisation represents the main reason to systematically avoid the re-use of data. The urban groundwater data shows the same complex situation. The underground structures (subway lines, deep foundations, underground parkings, and others), the urban facility networks (sewer systems, water supply networks, heating conduits, etc), the drainage systems, the surface water works and many others modify continuously. As consequence, their influence on groundwater changes systematically. However, these activities provide a large quantity of data, aquifers modelling and then behaviour prediction can be done using monitored quantitative and qualitative parameters. Due to the rapid evolution of technology in the past few years, transferring large amounts of information through internet has now become a feasible solution for sharing geoscience data. Furthermore, standard platform-independent means to do this have been developed (specific mark-up languages like: GML, GeoSciML, WaterML, GWML, CityML). They allow easily large geospatial databases updating and sharing through internet, even between different companies or between research centres that do not necessarily use the same database structures. For Bucharest City (Romania) an integrated platform for groundwater geospatial data management is developed under the framework of a national research project - "Sedimentary media modeling platform for groundwater management in urban areas" (SIMPA) financed by the National Authority for Scientific Research of Romania. The platform architecture is based on three components: a geospatial database, a desktop application (a complex set of hydrogeological and geological analysis

  18. PEEX Modelling Platform for Seamless Environmental Prediction

    Science.gov (United States)

    Baklanov, Alexander; Mahura, Alexander; Arnold, Stephen; Makkonen, Risto; Petäjä, Tuukka; Kerminen, Veli-Matti; Lappalainen, Hanna K.; Ezau, Igor; Nuterman, Roman; Zhang, Wen; Penenko, Alexey; Gordov, Evgeny; Zilitinkevich, Sergej; Kulmala, Markku

    2017-04-01

    The Pan-Eurasian EXperiment (PEEX) is a multidisciplinary, multi-scale research programme stared in 2012 and aimed at resolving the major uncertainties in Earth System Science and global sustainability issues concerning the Arctic and boreal Northern Eurasian regions and in China. Such challenges include climate change, air quality, biodiversity loss, chemicalization, food supply, and the use of natural resources by mining, industry, energy production and transport. The research infrastructure introduces the current state of the art modeling platform and observation systems in the Pan-Eurasian region and presents the future baselines for the coherent and coordinated research infrastructures in the PEEX domain. The PEEX modeling Platform is characterized by a complex seamless integrated Earth System Modeling (ESM) approach, in combination with specific models of different processes and elements of the system, acting on different temporal and spatial scales. The ensemble approach is taken to the integration of modeling results from different models, participants and countries. PEEX utilizes the full potential of a hierarchy of models: scenario analysis, inverse modeling, and modeling based on measurement needs and processes. The models are validated and constrained by available in-situ and remote sensing data of various spatial and temporal scales using data assimilation and top-down modeling. The analyses of the anticipated large volumes of data produced by available models and sensors will be supported by a dedicated virtual research environment developed for these purposes.

  19. Toward an E-Government Semantic Platform

    Science.gov (United States)

    Sbodio, Marco Luca; Moulin, Claude; Benamou, Norbert; Barthès, Jean-Paul

    This chapter describes the major aspects of an e-government platform in which semantics underpins more traditional technologies in order to enable new capabilities and to overcome technical and cultural challenges. The design and development of such an e-government Semantic Platform has been conducted with the financial support of the European Commission through the Terregov research project: "Impact of e-government on Territorial Government Services" (Terregov 2008). The goal of this platform is to let local government and government agencies offer online access to their services in an interoperable way, and to allow them to participate in orchestrated processes involving services provided by multiple agencies. Implementing a business process through an electronic procedure is indeed a core goal in any networked organization. However, the field of e-government brings specific constraints to the operations allowed in procedures, especially concerning the flow of private citizens' data: because of legal reasons in most countries, such data are allowed to circulate only from agency to agency directly. In order to promote transparency and responsibility in e-government while respecting the specific constraints on data flows, Terregov supports the creation of centrally controlled orchestrated processes; while the cross agencies data flows are centrally managed, data flow directly across agencies.

  20. Research

    African Journals Online (AJOL)

    abp

    2017-10-25

    Oct 25, 2017 ... stigma and superstition are known to lead to frequent presentation .... The limited documented research on challenges to help-seeking behaviour for cancer ..... to touch your breast [16] that breast self-examination may cause.

  1. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-10-02

    Oct 2, 2015 ... thought to prevent infection, but recent research has proven otherwise. In addition ... One patient had ophthalmalgia and was exposed to. Kaiy for one year and ... migraine, ear infections, tuberculosis, bone fractures, epilepsy,.

  2. Research

    African Journals Online (AJOL)

    abp

    2016-07-12

    Jul 12, 2016 ... multiple risk factors provides support for multiple-behavior interventions as ... consumption) with smoking therefore needs further research. As such this study .... restaurants, in bars, and on a statewide basis. They preferred to.

  3. Research

    African Journals Online (AJOL)

    The mini-clinical-evaluation exercise (mini-CEX) is a way of assessing the clinical ... Ethical approval for this study was obtained from the Medical Health. Research ..... mini-CEX assessment and feedback session, the greater the likelihood of.

  4. Research

    African Journals Online (AJOL)

    abp

    2016-04-14

    Apr 14, 2016 ... Qualitative data, content analysis approach was used. Results: Overall 422 .... Study design: A mixed method cross-sectional design using both quantitative and qualitative research methods as described by. Hanson et al [33] ...

  5. Research

    International Nuclear Information System (INIS)

    1999-01-01

    Subjects covered in this section are: (1) PCAST panel promotes energy research cooperation; (2) Letter issued by ANS urges funding balance in FFTF restart consideration and (3) FESAC panel releases report on priorities and balance

  6. Research

    African Journals Online (AJOL)

    Research. December 2017, Vol. 9, No. 4 AJHPE 171. During curriculum development, teachers ... Ideally, examiners need an educational method to determine ..... A major focus of this study was addressing the human resource gap when.

  7. Study on concept of web-based reactor piping design data platform

    International Nuclear Information System (INIS)

    Wang Yu; Zhou Yu; Dong Jianling; Meng Yang

    2005-01-01

    For solving the piping design problems such as design data deficiency, designer communication inconvenience and design project inconsistence, Reactor Piping Design Database Platform, which is the main part of the Integrated Nuclear Project Research Platform, is proposed by analyzing the nuclear piping designs in detail. The functions and system structures of the platform are described in the paper for the sake of the realization of the Reactor Piping Design Database Platform. The platform is constituted by web-based management interface, AutoPlant selected as CAD software, and relation database management system (DBMS). (authors)

  8. Balancing platform control and external contribution in third-party development: the boundary resources model

    DEFF Research Database (Denmark)

    Ghazawneh, Ahmad; Henfridsson, Ola

    2013-01-01

    Prior research documents the significance of using platform boundary resources (e.g. application programming interfaces) for cultivating platform ecosystems through third-party development. However, there are few, if any, theoretical accounts of this relationship. To this end, this paper proposes......-party development: self-resourcing, regulation-based securing, diversity resourcing and sovereignty securing. Our research extends and complements existing platform literature and contributes new knowledge about an alternative form of system development...

  9. El campus virtual como recurso útil: un estudio de estudiantes universitarios de carreras humanísticas [The virtual learning platform as a useful resource: a research among university students of humanistic degrees

    Directory of Open Access Journals (Sweden)

    Carmen Luján-García

    2012-06-01

    Full Text Available Resumen:Este artículo, realizado con estudiantes universitarios de dos carreras humanísticas en la Universidad de Las Palmas de Gran Canaria: Filología Inglesa y Geografía, investiga el grado de familiaridad y utilidad del campus virtual en el mundo académico. Los resultados demuestran que es una herramienta útil, aunque percibida más como un apoyo a la enseñanza presencial que con validez en sí misma. La variable género revela que los hombres valoran mejor esta herramienta, mientras que los informantes de geografía perciben más positivamente el campus virtual que los de filología inglesa. Abstract:This paper presents the results of a study carried out among undergraduate students of English Language and Literature and Geography at the University of Las Palmas de Gran Canaria to investigate their degree of familiarity with and the general usefulness of the virtual learning platform in Higher Education. The results show that whilst this is indeed a useful tool, it is used to best effect when seen as a supportive resource for regular education. The variation in responses from men and women reveals that men are more familiar with and value this tool more highly than women. It was also found that the Geography Undergraduates have a more positive view of virtual learning platforms than English Language and Literature Undergraduates.

  10. The Research and Exploration of the Integration Platform of Hospital Information System Based on Ensemble%基于Ensemble的医院信息系统集成平台的研究与探索

    Institute of Scientific and Technical Information of China (English)

    曹茂诚; 陈旭; 何及夫; 牛启润

    2012-01-01

    目的:在医院内部信息系统集成方面,传统点对点接口通信模式存在系统耦合度高,系统整体稳定性和安全性难以预测和控制等隐患.不同业务系统之间难以实现数据交换与资源共享.如何打造一个稳定、高效、安全、可管理的集成平台,以满足不断变化的应用需求是一个亟待解决的问题.方法:将Ensemble集成平台技术引入到医院信息化建设中进行研究是一项非常有意义的工作,在分析传统点对点接口通信模式不足的基础上,文章结合Ensemble集成平台技术,建立了以病人为中心的统一视图,实现了跨平台的数据交换与共享.结果:通过Ensemble集成平台技术建立了以患者就诊流程为核心的内部信息共享交互平台,实现了全院数据交换与共享,消除了“信息孤岛”,实现了新业务应用的快速部署.结论:Ensemble集成平台技术为医院业务变革提供了灵活的、快速实施和部署的系统架构,实现了医疗信息的交换与共享,优化了服务流程,提高了医院运营效率,满足了医院信息化可持续发展.%Objective: In the integration of hospital internal information system, the traditional point to point interface of communication mode exist high coupling of systems, also have many hidden trouble in the stability and safety of global system that are hard to foresee and control. It is difficult to exchange data and share resource in different business systems. How to build a stable, efficient, safety and control integration to meet the changing application requirements is a problem to be solved imperatively. Methods: Introducing integration platform of ensemble into hospital information construction is a significant and valuable work, based on the deficiency of traditional point to point interface of communication mode, combined with integration platform of ensemble, contribute to build "patient-centered" unified view, realize the data exchange and resource

  11. Stratifying the Develoment of Product Platforms

    DEFF Research Database (Denmark)

    Sköld, Martin; Karlsson, Christer

    2013-01-01

    companies develop platforms for different aims, purposes, and product scopes. Following on from this, the requirements for platform development resources, the ways of organizing platform development, and the implications for management styles have not been explored and are presumably varying. To start...... influencing the project length, requirements for platform development resources, principles for organizing, and implications for management styles....

  12. The Educational Platform: Constructing Conceptual Frameworks.

    Science.gov (United States)

    Peca, Kathy; Isham, Mark

    2001-01-01

    The education faculty at Eastern New Mexico University used educational platforms as a means of developing the unit's conceptual framework. Faculty members developed personal platforms, then synthesized them into one curricular area platform. The resultant unit educational platform became the basis for the unit's conceptual framework, which…

  13. New offshore platform in the Mexican Gulf

    Energy Technology Data Exchange (ETDEWEB)

    Beisel, T.

    1982-04-01

    After a construction period of only 10 months, the second steel Offshore platform was recently completed in the Mexican Gulf. The pattern for this structure was the Cognac platform. The erection of the new platform, called the 'Cerveza' platform, is described in the article.

  14. The Dynamics of Digital Platform Innovation

    DEFF Research Database (Denmark)

    Eaton, Ben

    2016-01-01

    Curated platforms provide an architectural basis for third parties to develop platform complements and for platform owners to control their implementation as a form of open innovation. The refusal to implement complements as innovations can cause tension between platform owners and developers. Th...

  15. The design and implementation of a network simulation platform

    CSIR Research Space (South Africa)

    Von Solms, S

    2013-11-01

    Full Text Available these events and their effects can enable researchers to identify these threats and find ways to counter them. In this paper we present the design of a network simulation platform which can enable researchers to study dynamic behaviour of networks, network...

  16. The novel cloud application technology with virtual platform

    Directory of Open Access Journals (Sweden)

    Chen Ying-Chuan

    2018-01-01

    Full Text Available Virtualization technology of cloud application service is the major research issue in recent years. Our virtual platform can obtain a lot of advantages base on virtualization technology with suitable virtual machine solution that all system resources can deployed quickly and managed competently, and it has some features including the high capacity for reliability, elasticity and customization. In our virtual platform, there are many different application services are provided for cloud service style. For system computing resources, we need to share all of system and software resources using the virtualization technology is presented in related sections, and we proposed virtual and remote application technology to implement innovative, convenient and powerful cloud application service base on virtual platform. For users of our platform, they can easy to use any software and tools on demand with pay per use mode anytime, and they do not have specialized knowledge and ability of install and maintenance.

  17. Towards A Framework of Digital Payment Platform Design

    DEFF Research Database (Denmark)

    Kazan, Erol; Damsgaard, Jan

    This paper focuses on the triumph march of mobile phones that currently are annexing music players, navigation devices, and cameras as separate physical objects. The next target is set on payment. Through synthesizing available literature, we construct a framework for studying digital payment...... platforms that combines platform, technology and business design aspects. The framework is applied to conduct a comparative case study of digital payment platforms. Four types of market actors are considered: banks, mobile network operators, merchants, and startups, which are incumbents and disrupters....... By hosting third-party services, payment instruments are evolving from single-purpose to multi-functional ones. Our research extends existing payment literature from the MSP perspective to emphasize certain digital payment platform components, which impact strategies and complementary products....

  18. Building a Community-Focused Data Platform

    Energy Technology Data Exchange (ETDEWEB)

    Turk, Matthew J. [Univ. of Illinois, Urbana-Champaign, IL (United States). National Center for Supercomputing Applications (NCSA); Warren, Michael S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Skillman, Samuel W. [Stanford Univ., CA (United States)

    2014-06-10

    The National Data Service (NDS) presents a broad-reaching vision of integrating discovery, publishing, and sharing of data. Metcalfe's Law states that the value of a network increases with the number of connections in the network, not the number of nodes. The NDS must develop and steward connections not only between data, as is in its vision statement, but between individuals as well. We propose that this be accomplished by explicitly developing it as a platform on which data exploration can be constructed by individual researchers.

  19. Research

    African Journals Online (AJOL)

    abp

    2017-05-18

    May 18, 2017 ... available to populations of developing countries [2-5]. In 2013, in. Western and Central Europe and ..... initiation among the infected persons in the community. Addressing stigma and educating ... Lifespan/Tufts/Brown Center for AIDS Research (P30AI042853). Tables. Table 1: Baseline characteristics of ...

  20. Research

    African Journals Online (AJOL)

    abp

    15 févr. 2016 ... présentent un Indice de Masse Corporel (IMC) normal, les autres femmes sont soit ..... In The health belief model and personal health behavior, edited by MH ... Evaluation of the Osteoporosis Health Belief Scale. Research in.

  1. Research

    African Journals Online (AJOL)

    2017-03-14

    Mar 14, 2017 ... R Ebrahim,1 MSc (Dent); H Julie,2 MPH, MCur, PhD. 1 Extended ... and research is applied to develop and sustain society.[5]. Methods .... service they want, not the service we want to give whether they want it or. Co math. G.

  2. Research

    African Journals Online (AJOL)

    abp

    2017-11-24

    Nov 24, 2017 ... Page number not for citation purposes. 1. Prevalence and determinants of common mental ..... illnesses were smoke cigarette in the last 3 months that make prevalence of tobacco use 38.2%. ..... Okasha A, Karam E.Mental health services and research in the. Arab world. Acta Psychiatrica Scandinavica.

  3. Research

    African Journals Online (AJOL)

    abp

    2014-04-21

    Apr 21, 2014 ... Prospective assessment of the risk of obstructive sleep apnea in ... Faculty of Clinical Sciences, College of Medicine, University of .... University Teaching Hospital Health Research Ethics Committee ... BANG, Berlin questionnaire and the American Society of .... The epidemiology of adult obstructive sleep.

  4. Research

    African Journals Online (AJOL)

    abp

    2016-02-01

    Feb 1, 2016 ... University Hospital, DK-5000 Odense, Denmark, 3Center for Global Health, Institute of Clinical Research, University of Southern Denmark, DK-5000. Odense .... BHP is a Danish-Guinean Demographic Surveillance Site with a study-area .... variables such as age groups, previous military duty, history of.

  5. Research

    African Journals Online (AJOL)

    abp

    2015-06-24

    Jun 24, 2015 ... related immunosuppression, previous history of TB, and pause in treatment [6]. In Brazil, researchers .... treatment, use of traditional medicines or herbs, history of TB drug side effects and treatment delay). ..... therapy for pulmonary tuberculosis in Lima Ciudad, Peru. International journal of tuberculosis and ...

  6. Research

    African Journals Online (AJOL)

    Research. May 2016, Vol. 8, No. 1 AJHPE 37. Students who enrol in occupational therapy (OT) at the. University of Kwa Zulu-Natal (UKZN), Durban, South Africa ... The latter may include becoming familiar with the disintegrating social systems in primary .... They also lacked the skills needed to adapt sessions and failed to ...

  7. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-06-22

    Jun 22, 2015 ... collaboration with Makerere University, School of Public Health. We acknowledge The Family Health Research and Development Centre. (FHRDC) Uganda. Supported by Bill & Melinda Gates Institute for. Population & Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, ...

  8. Research

    African Journals Online (AJOL)

    However, a focus on competence alone is inadequate to produce graduates who are capable of adapting to the changing needs of health systems. While knowledge and technical ... shared their responses to guided questions. There were three sessions; after each session the researcher aggregated participant responses ...

  9. Research

    African Journals Online (AJOL)

    abp

    2014-01-31

    Jan 31, 2014 ... by Hazarika in a population-based study in India. The researcher noted that patients' preference to the private health facilities was due mainly to their dissatisfaction with the services in the public health facilities [11]. Furthermore, the quality of the services in the private health facilities could also be a major ...

  10. Research

    African Journals Online (AJOL)

    2018-03-20

    Mar 20, 2018 ... student health professionals in various institutions, both in South Africa. (SA) and internationally. ... field include dentists, dental therapists and oral hygienists in training, .... The College of Health Sciences at UKZN has four schools: clinical ..... Journal of Emerging Trends in Educational Research and Policy ...

  11. Research

    African Journals Online (AJOL)

    abp

    2017-09-14

    Sep 14, 2017 ... Abstract. Introduction: Medical and dental students are a high-risk group for hepatitis B virus (HBV) infection which is an ... The Pan African Medical Journal - ISSN 1937-8688. ... Research ... in the College of Health Sciences and clinical students (years four to .... Hepatology International.2017 Jan; 11(1):.

  12. Research

    African Journals Online (AJOL)

    abp

    2015-01-19

    Jan 19, 2015 ... One research assistant was available to assist the learners and to answer questions while they completed the questionnaires during a classroom period. ..... PubMed | Google Scholar. 4. Hall PA, Holmqvist M, Sherry SB. Risky adolescent sexual behaviour: A psychological perspective for primary care.

  13. Moodle vs. Social Media Platforms

    DEFF Research Database (Denmark)

    Gulieva, Valeria

    Given the competition coming from various social media platforms, it is explored in this paper how students could be encouraged to use Moodle more proactively during their studies. Moodle is a course management system for online learning. It is designed to be a flexible template-based system, which......, known and widely used social platforms. It might be also due to the fact that students do not see the benefits in investing time and efforts in learning the new system. Another reason might be the mandatory nature of Moodle, i.e., it is imposed on students, rather than a free choice – and this might...

  14. Towards a Framework of Digital Platform Competition

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    2016-01-01

    between monopolistic (i.e., Pingit) and federated (i.e., Paym) mobile payment platforms to illustrate its applicability and yield principles on the nature and impact of competition among platform-driven ubiquitous systems. Preliminary findings indicate that monopolistic mobile digital platforms attempt...... to create unique configurals to obtain monopolistic power by tightly coupling platform layers, which are difficult to replicate. Conversely, federated digital platforms compete by dispersing the service layer to harness the collective resources from individual firms. Furthermore, the interaction...

  15. Model Infrastruktur dan Manajemen Platform Server Berbasis Cloud Computing

    Directory of Open Access Journals (Sweden)

    Mulki Indana Zulfa

    2017-11-01

    Full Text Available Cloud computing is a new technology that is still very rapidly growing. This technology makes the Internet as the main media for the management of data and applications remotely. Cloud computing allows users to run an application without having to think about infrastructure and its platforms. Other technical aspects such as memory, storage, backup and restore, can be done very easily. This research is intended to modeling the infrastructure and management of computer platform in computer network of Faculty of Engineering, University of Jenderal Soedirman. The first stage in this research is literature study, by finding out the implementation model in previous research. Then the result will be combined with a new approach to existing resources and try to implement directly on the existing server network. The results showed that the implementation of cloud computing technology is able to replace the existing platform network.

  16. SNETP – Sustainable Nuclear Energy Technology Platform

    Energy Technology Data Exchange (ETDEWEB)

    Aït Abderrahim, Hamid

    2016-07-01

    SNETP is one of the EU’s official European Technology & Innovation Platforms established to implement the SET-Plan. SNETP and its pillars gather more than 120 European stakeholders involved in the research and innovation, deployment and operation of nuclear fission reactors and fuel cycle facilities: industry, research centres, universities, technical safety organisations, small and medium enterprises, service providers, non-governmental organisations. Despite industrial competition, SNETP has achieved efficient collaboration between its stakeholders. It has developed a common vision on the future contribution of nuclear fission energy in Europe, with the publication of a Vision Report, a Strategic Research & Innovation Agenda (two editions) and a Deployment Strategy report. It issued also a dedicated report on the R&D topics related to safety issues triggered by the Fukushima accident.

  17. Conducting research in the middle of the ocean. Platforms FINO 1-3 supply planning data for utilising offshore wind energy in the North and Baltic Seas; Forschen mitten im Meer. Plattformen FINO 1-3 liefern Planungsdaten fuer die Offshore-Windenergienutzung in Nord- und Ostsee

    Energy Technology Data Exchange (ETDEWEB)

    Milles, Uwe

    2011-07-01

    In the future, a large part of Germany's electricity requirement is intended to come from offshore wind farms in order to utilise the favourable wind conditions there. This represents unknown territory in both technical and ecological terms, and is taking place in sensitive biotopes. Three largely remote-controlled research platforms have therefore been constructed in the North and Baltic Seas (FINO). In particular it is being investigated into how the wind actually behaves above the sea and how much electricity can be generated. The data will be incorporated into the planning, design and certification of future farms. (orig.)

  18. NCI's Transdisciplinary High Performance Scientific Data Platform

    Science.gov (United States)

    Evans, Ben; Antony, Joseph; Bastrakova, Irina; Car, Nicholas; Cox, Simon; Druken, Kelsey; Evans, Bradley; Fraser, Ryan; Ip, Alex; Kemp, Carina; King, Edward; Minchin, Stuart; Larraondo, Pablo; Pugh, Tim; Richards, Clare; Santana, Fabiana; Smillie, Jon; Trenham, Claire; Wang, Jingbo; Wyborn, Lesley

    2016-04-01

    The Australian National Computational Infrastructure (NCI) manages Earth Systems data collections sourced from several domains and organisations onto a single High Performance Data (HPD) Node to further Australia's national priority research and innovation agenda. The NCI HPD Node has rapidly established its value, currently managing over 10 PBytes of datasets from collections that span a wide range of disciplines including climate, weather, environment, geoscience, geophysics, water resources and social sciences. Importantly, in order to facilitate broad user uptake, maximise reuse and enable transdisciplinary access through software and standardised interfaces, the datasets, associated information systems and processes have been incorporated into the design and operation of a unified platform that NCI has called, the National Environmental Research Data Interoperability Platform (NERDIP). The key goal of the NERDIP is to regularise data access so that it is easily discoverable, interoperable for different domains and enabled for high performance methods. It adopts and implements international standards and data conventions, and promotes scientific integrity within a high performance computing and data analysis environment. NCI has established a rich and flexible computing environment to access to this data, through the NCI supercomputer; a private cloud that supports both domain focused virtual laboratories and in-common interactive analysis interfaces; as well as remotely through scalable data services. Data collections of this importance must be managed with careful consideration of both their current use and the needs of the end-communities, as well as its future potential use, such as transitioning to more advanced software and improved methods. It is therefore critical that the data platform is both well-managed and trusted for stable production use (including transparency and reproducibility), agile enough to incorporate new technological advances and

  19. Verkenning locatiegegevens en sociale platforms

    NARCIS (Netherlands)

    van Loenen, B.; Kilic, Deniz; Van de Velde, Rob

    2017-01-01

    In deze rapportage hebben we ons verdiept in de wereld van de commerciële toepassingen van sensordata, waarin locatiegegevens van smartphones op grote schaal worden vastgelegd. Een beter inzicht in de wereld van de sociale en commerciële platforms zou ervoor moeten zorgen dat deze beter begrepen

  20. 2009 Analysis Platform Review Report

    Energy Technology Data Exchange (ETDEWEB)

    Ferrell, John [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States

    2009-12-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the U.S. Department of Energy Biomass Program’s Analysis platform review meeting, held on February 18, 2009, at the Marriott Residence Inn, National Harbor, Maryland.