WorldWideScience

Sample records for research laboratory arl

  1. Aquatic Research Laboratory (ARL)

    Data.gov (United States)

    Federal Laboratory Consortium — Columbia River and groundwater well water sources are delivered to the Aquatic Research Laboratory (ARL), where these resources are used to conduct research on fish...

  2. ARL Profiles: Research Libraries 2010

    Science.gov (United States)

    Potter, William Gray; Cook, Colleen; Kyrillidou, Martha

    2011-01-01

    The current ARL report summarizes a multi-year effort that captures evidence in the form of narrative profiles as it delivers the message of the value and contributions of research libraries during transformative times. When ARL library directors were interviewed in 2005 and asked to describe a research library in the 21st century, there was…

  3. Fine-grained policy control in U.S. Army Research Laboratory (ARL) multimodal signatures database

    Science.gov (United States)

    Bennett, Kelly; Grueneberg, Keith; Wood, David; Calo, Seraphin

    2014-06-01

    The U.S. Army Research Laboratory (ARL) Multimodal Signatures Database (MMSDB) consists of a number of colocated relational databases representing a collection of data from various sensors. Role-based access to this data is granted to external organizations such as DoD contractors and other government agencies through a client Web portal. In the current MMSDB system, access control is only at the database and firewall level. In order to offer finer grained security, changes to existing user profile schemas and authentication mechanisms are usually needed. In this paper, we describe a software middleware architecture and implementation that allows fine-grained access control to the MMSDB at a dataset, table, and row level. Result sets from MMSDB queries issued in the client portal are filtered with the use of a policy enforcement proxy, with minimal changes to the existing client software and database. Before resulting data is returned to the client, policies are evaluated to determine if the user or role is authorized to access the data. Policies can be authored to filter data at the row, table or column level of a result set. The system uses various technologies developed in the International Technology Alliance in Network and Information Science (ITA) for policy-controlled information sharing and dissemination1. Use of the Policy Management Library provides a mechanism for the management and evaluation of policies to support finer grained access to the data in the MMSDB system. The GaianDB is a policy-enabled, federated database that acts as a proxy between the client application and the MMSDB system.

  4. Advances in the design, development, and deployment of the U.S. Army Research Laboratory (ARL) multimodal signatures database

    Science.gov (United States)

    Bennett, Kelly; Robertson, James

    2011-06-01

    Recent advances in the design, development, and deployment of U.S. Army Research Laboratory's (ARL) Multimodal Signature Database (MMSDB) create a state-of-the-art database system with Web-based access through a Web interface designed specifically for research and development. Tens of thousands of signatures are currently available for researchers to support their algorithm development and refinement for sensors and other security systems. Each dataset is stored in (Hierarchical Data Format 5 (HDF5) format for easy modeling and storing of signatures and archived sensor data, ground truth, calibration information, algorithms, and other documentation. Archived HDF5 formatted data provides the basis for computational interoperability across a variety of tools including MATLAB, Octave, and Python. The database has a Web-based front-end with public and restricted access interfaces, along with 24/7 availability and support. This paper describes the overall design of the system, and the recent enhancements and future vision, including the ability for researchers to share algorithms, data, and documentation in the cloud, and providing an ability to run algorithms and software for testing and evaluation purposes remotely across multiple domains and computational tools. The paper will also describe in detail the HDF5 format for several multimodal sensor types.

  5. US Army Research Laboratory (ARL) Robotics Collaborative Technology Alliance 2014 Capstone Experiment

    Science.gov (United States)

    2016-07-01

    42 Fig. 31 (left) The experimental setup for terrain classification using PreSRS on the Hopper . (right) A computer-aided design schematic of the... Hopper with PreSRS attached to the bottom of the robot foot. ........................44 Fig. 32 Plots of terrain classification accuracy vs. sensor...2.1 Robotics CTA The RCTA is a fundamental research program that began in 2010 and enables Government, industrial , and academic institutions to

  6. ARL: A Bimonthly Report on Research Library Issues and Actions from ARL, CNI, and SPARC. Number 259

    Science.gov (United States)

    Barrett, G. Jaia, Ed.

    2008-01-01

    "ARL" is the bimonthly report on research library issues and actions from ARL (Association of Research Libraries), CNI (Coalition of Networked Information), and SPARC (Scholarly Publishing and Academic Resources Coalition). "ARL" reports on current issues of interest to academic and research library administrators, staff, and users; higher…

  7. Maintaining the Database for Information Object Analysis, Intent, Dissemination and Enhancement (IOAIDE) and the US Army Research Laboratory Campus Sensor Network (ARL CSN)

    Science.gov (United States)

    2017-01-01

    operations as well as basic knowledge of Microsoft Structured Query Language Server Management Studio (2014 or 2016). 15. SUBJECT TERMS Microsoft SQL ...designed and is maintained with Microsoft SQL Server Management Studio. The basic requirements for the IOAIDE/ARL CSN database development and... SQL server (2014 or 2016) installed. All images in this report were generated using Windows 10. The IOAIDE/ARL CSN database could reside on the

  8. Standard Operating Procedure for Accelerated Corrosion Testing at ARL

    Science.gov (United States)

    2017-11-01

    ARL-TN-0855 ● NOV 2017 US Army Research Laboratory Standard Operating Procedure for Accelerated Corrosion Testing at ARL by... Corrosion Testing at ARL by Thomas A Considine Weapons and Materials Research Directorate, ARL Approved for public...November 2017 2. REPORT TYPE Technical Note 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE Standard Operating Procedure for Accelerated

  9. The ARL 2030 Scenarios: A User's Guide for Research Libraries

    Science.gov (United States)

    Association of Research Libraries, 2010

    2010-01-01

    This user's guide was developed to advance local planning at ARL member libraries. It is written for library leaders writ large and for anyone leading or contributing to research library planning processes. Users do not need advanced facilitation skills to benefit from this guide, but facilitators charged with supporting scenario planning will…

  10. ARL Summer Student Research Symposium Volume I: Select Presentations

    Science.gov (United States)

    2017-06-01

    papers to an audience of ARL scientists and engineers, including the ARL Director and an ARL Fellows panel. This volume of the Summer Student Symposium...program. As an integral part of their summer study, all students are required to write a paper on their work which summarizes their major activity and its...end product. The program is conducted on two separate competitive levels: undergraduate and graduate. The format of the paper in both levels is the

  11. Research Library Issues: A Bimonthly Report from ARL, CNI, and SPARC. RLI 268

    Science.gov (United States)

    Barrett, G. Jaia, Ed.

    2010-01-01

    "Research Library Issues" ("RLI") is a bimonthly report from ARL (Association of Research Libraries), CNI (Coalition of Networked Information), and SPARC (Scholarly Publishing and Academic Resources Coalition). This special issue includes the following articles: (1) Themes within the ARL Strategic Plan 2010-2012 (Charles B. Lowry); (2) ARL…

  12. Relationships between Association of Research Libraries (ARL) Statistics and Bibliometric Indicators: A Principal Components Analysis

    Science.gov (United States)

    Hendrix, Dean

    2010-01-01

    This study analyzed 2005-2006 Web of Science bibliometric data from institutions belonging to the Association of Research Libraries (ARL) and corresponding ARL statistics to find any associations between indicators from the two data sets. Principal components analysis on 36 variables from 103 universities revealed obvious associations between…

  13. Cyber Defense Research and Monitoring Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This facility acts as a fusion point for bridging ARL's research in tactical and operational Information Assurance (IA) areas and the development and assessment of...

  14. Research@ARL. Volume 4, Issue 1, November 2015

    Science.gov (United States)

    2015-11-01

    devices has not met expectations. This is due primarily to an incomplete understanding of their electronic processes, for example, their complex band...fact, able to distinguish RDX from non-explosive materials. For example, ARL found that the molecular formation and subsequent decay of cyanide (a...and robustness to challenging tactical communication environments that may include complex (e.g., urban or mountainous) terrain or RF congestion or

  15. Research@ARL: Autonomous Systems. Volume 2, Issue 2

    Science.gov (United States)

    2013-07-01

    communication delays (latency) limit operational tempo . More limiting, tele-operation requires at least one dedicated pair of eyes and hands. In...fabrication process (see schematic in Fig. 3) for PiezoMEMS devices at ARL uses the following process flow with minor variations (i.e., release...57 [12] 3229–38 (2009). 47M. Glickman, P. Tseng, P. Harison, J. Niblock, T. Goldberg , I. B. Judy, and J. W. Judy, “High Performance Lateral Actuating

  16. DEPSCOR: Research on ARL's Intelligent Control Architecture: Hierarchical Hybrid-Model Based Design, Verification, Simulation, and Synthesis of Mission Control for Autonomous Underwater Vehicles

    National Research Council Canada - National Science Library

    Kumar, Ratnesh; Holloway, Lawrence E

    2007-01-01

    ... modeling, verification, simulation and automated synthesis of coordinators has lead to research in this area. We have worked and are working on these issues with Applied Research Laboratory (ARL) at Pennsylvania State University (PSU) who have designed autonomous underwater vehicles for over 50 years primarily under the support of the U.S. Navy through the Office of Naval Research (ONR).

  17. Network Science Research Laboratory (NSRL) Discrete Event Toolkit

    Science.gov (United States)

    2016-01-01

    ARL-TR-7579 ● JAN 2016 US Army Research Laboratory Network Science Research Laboratory (NSRL) Discrete Event Toolkit by...Laboratory (NSRL) Discrete Event Toolkit by Theron Trout and Andrew J Toth Computational and Information Sciences Directorate, ARL...Research Laboratory (NSRL) Discrete Event Toolkit 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Theron Trout

  18. Research Library Issues: A Quarterly Report from ARL, CNI, and SPARC. RLI 279

    Science.gov (United States)

    Baughman, M. Sue, Ed.

    2012-01-01

    "Research Library Issues" ("RLI") is a quarterly report from ARL (Association of Research Libraries), CNI (Coalition of Networked Information), and SPARC (Scholarly Publishing and Academic Resources Coalition). This issue includes the following articles: (1) Digitization of Special Collections and Archives: Legal and Contractual Issues (Peter B.…

  19. Research Library Issues: A Quarterly Report from ARL, CNI, and SPARC. RLI 277

    Science.gov (United States)

    Baughman, M. Sue, Ed.

    2011-01-01

    "Research Library Issues" ("RLI") is a quarterly report from ARL (Association of Research Libraries), CNI (Coalition of Networked Information), and SPARC (Scholarly Publishing and Academic Resources Coalition). This issue includes the following articles: (1) Rebalancing the Investment in Collections (H. Thomas Hickerson); (2)…

  20. ARL Summer Student Research Symposium. Volume 1: Select Papers

    Science.gov (United States)

    2012-08-01

    deploying Android smart phones and tablets on the battlefield, which may be a target for malware. In our research, we attempt to improve static...network. (a) The T1 and MRI images are (b) segmented into different material components. The segmented geometry is then used to create (c) a finite element...towards finding a method to detect mTBI non-invasively. One method in particular includes the use of a magnetic resonance image ( MRI )-based imaging

  1. US Army Research Laboratory Lightweight and Specialty Metals Branch Research and Development (FY14)

    Science.gov (United States)

    2015-04-01

    2014 Feb. Report No.: ARL-TR- 6807. 8) Grendahl SM, Kellogg F, Nguyen H. Effect of cleanliness on hydrogen toler- ance in high-strength steel...SJ, Kellogg F, Nguyen H, Runk D. Ul- trasonic shot peening for aviation components. Aberdeen Proving Ground (MD): Army Research Laboratory (US); 2013...M. Grendahl Weapons and Materials Research Directorate, ARL Franklyn Kellogg and Hoang Nguyen Bowhead Technical Services

  2. Evolving the US Army Research Laboratory (ARL) Technical Communication Strategy

    Science.gov (United States)

    2016-10-01

    communication strategy. However, if the goal is to build support for Army S&T within the general public, then community outreach, mass media , and concise...Content into Popular Media 14 2.3 Leveraging Established S&T Audiences 15 3. Prong 2: Improve Workforce Technical and Strategic Communications Skills 16... community organization, STEM-related, activities (FIRST, Scouts, Citizen School), videos Permanent exhibit at a museum, quarterly for media

  3. ARL Supplementary Statistics, 2006-2007

    Science.gov (United States)

    Bland, Les, Comp.; Kyrillidou, Martha, Comp.

    2009-01-01

    This report presents statistics on how Association of Research Libraries (ARL) member libraries spend money on electronic resources. This report indicates that 108 ARL libraries purchased 25,006,758 electronic books. In 2006-2007, there was an ARL median of 243,725 acquisitions of electronic books (this includes one institution that purchased…

  4. ARL Supplementary Statistics, 2007-2008

    Science.gov (United States)

    Bland, Les, Comp.; Kyrillidou, Martha, Comp.

    2009-01-01

    This report presents statistics on how Association of Research Libraries (ARL) member libraries spend money on electronic resources. This report indicates that 109 ARL libraries purchased 32,329,187 electronic books. In 2007-2008, there was a median of 28,319 acquisitions of electronic books by ARL libraries (this includes one institution that…

  5. Electronic Journals in Academic Libraries: A Comparison of ARL and Non-ARL Libraries.

    Science.gov (United States)

    Shemberg, Marian; Grossman, Cheryl

    1999-01-01

    Describes a survey dealing with academic library provision of electronic journals and other electronic resources that compared ARL (Association of Research Libraries) members to non-ARL members. Highlights include full-text electronic journals; computers in libraries; online public access catalogs; interlibrary loan and electronic reserves; access…

  6. Research Combustion Laboratory (RCL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Research Combustion Laboratory (RCL) develops aerospace propulsion technology by performing tests on propulsion components and materials. Altitudes up to 137,000...

  7. Combustion Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Combustion Research Laboratory facilitates the development of new combustion systems or improves the operation of existing systems to meet the Army's mission for...

  8. Research@ARL: Materials Modeling at Multiple Scales. Volume 3, Issue 2

    Science.gov (United States)

    2014-07-01

    Communications Magazine 35 (1997) 46–55. [25] A. Sussman, Building complex coupled physical simulations on the grid with intercomm, Engineering with...microbiologist in the Biotechnology Branch of the Sensors and Electronic Devices Directorate. Her research area focuses on the genetic engineering of...engineering, with a Ph.D. in computational chemistry from the University of Maryland Baltimore County (UMBC), an M.S in biotechnology from Johns

  9. Energy Materials Research Laboratory (EMRL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Energy Materials Research Laboratory at the Savannah River National Laboratory (SRNL) creates a cross-disciplinary laboratory facility that lends itself to the...

  10. Simula Research Laboratory

    CERN Document Server

    Tveito, Aslak

    2010-01-01

    The Simula Research Laboratory, located just outside Oslo in Norway, is rightly famed as a highly successful research facility, despite being, at only eight years old, a very young institution. This fascinating book tells the history of Simula, detailing the culture and values that have been the guiding principles of the laboratory throughout its existence. Dedicated to tackling scientific challenges of genuine social importance, the laboratory undertakes important research with long-term implications in networks, computing and software engineering, including specialist work in biomedical comp

  11. NASA's Propulsion Research Laboratory

    Science.gov (United States)

    2004-01-01

    The grand opening of NASA's new, world-class laboratory for research into future space transportation technologies located at the Marshall Space Flight Center (MSFC) in Huntsville, Alabama, took place in July 2004. The state-of-the-art Propulsion Research Laboratory (PRL) serves as a leading national resource for advanced space propulsion research. Its purpose is to conduct research that will lead to the creation and development of innovative propulsion technologies for space exploration. The facility is the epicenter of the effort to move the U.S. space program beyond the confines of conventional chemical propulsion into an era of greatly improved access to space and rapid transit throughout the solar system. The laboratory is designed to accommodate researchers from across the United States, including scientists and engineers from NASA, the Department of Defense, the Department of Energy, universities, and industry. The facility, with 66,000 square feet of useable laboratory space, features a high degree of experimental capability. Its flexibility allows it to address a broad range of propulsion technologies and concepts, such as plasma, electromagnetic, thermodynamic, and propellant propulsion. An important area of emphasis is the development and utilization of advanced energy sources, including highly energetic chemical reactions, solar energy, and processes based on fission, fusion, and antimatter. The Propulsion Research Laboratory is vital for developing the advanced propulsion technologies needed to open up the space frontier, and sets the stage of research that could revolutionize space transportation for a broad range of applications.

  12. Green Building Research Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Sailor, David Jean [Portland State Univ., Portland, OR (United States)

    2013-12-29

    This project provided support to the Green Building Research Laboratory at Portland State University (PSU) so it could work with researchers and industry to solve technical problems for the benefit of the green building industry. It also helped to facilitate the development of PSU’s undergraduate and graduate-level training in building science across the curriculum.

  13. The underground research laboratories

    International Nuclear Information System (INIS)

    1997-06-01

    This educational booklet is a general presentation of the selected sites for the installation of underground research laboratories devoted to the feasibility studies of deep repositories for long-life radioactive wastes. It describes the different type of wastes and their management, the management of long life radioactive wastes, the site selection and the 4 sites retained, the preliminary research studies, and the other researches carried out in deep disposal facilities worldwide. (J.S.)

  14. Approval Plans in ARL Libraries. Kit 83.

    Science.gov (United States)

    Leonhardt, Thomas W.

    Materials in this collection were submitted by respondents to a survey which sought specific data on the numbers and types of approval plans in Association of Research Libraries (ARL) libraries, whether such plans are meeting expectations, their relative importance in the library, who makes the key decisions, and the kind of thought and study that…

  15. Application of the Fractions Skill Score for Tracking the Effectiveness of Improvements Made to Weather Research and Forecasting Model Simulations

    Science.gov (United States)

    2017-11-22

    Sciences Directorate ATTN: RDRL-CIE-M White Sands Missile Range, NM 88002 8. PERFORMING ORGANIZATION REPORT NUMBER ARL-TR-8217 9. SPONSORING...assessment of the weather running estimate−nowcast (WRE−N). White Sands Missile Range (NM): Army Research Laboratory (US); 2016 Aug. Report No.: ARL-TR...observations into the model so that forecast quality is improved (Stauffer and Seaman 1994; Deng et al. 2009). The US Army Research Laboratory (ARL

  16. Metallurgical Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The purpose is to increase basic knowledge of metallurgical processing for controlling the microstructure and mechanical properties of metallic aerospace alloys and...

  17. Materials Behavior Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The purpose is to evaluate mechanical properties of materials including metals, intermetallics, metal-matrix composites, and ceramic-matrix composites under typical...

  18. Laboratory for Large Data Research

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: The Laboratory for Large Data Research (LDR) addresses a critical need to rapidly prototype shared, unified access to large amounts of data across both the...

  19. The National Fire Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The National Fire Research Laboratory (NFRL) is adding a unique facility that will serve as a center of excellence for fireperformance of structures ranging in size...

  20. Geocentrifuge Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The geocentrifuge subjects a sample to a high-gravity field by spinning it rapidly around a central shaft. In this high-gravity field, processes, such as fluid flow,...

  1. Sandia National Laboratories: Research

    Science.gov (United States)

    Energy Stationary Power Earth Science Transportation Energy Energy Research Global Security WMD and decision-making. Materials science Leading the nation in the knowledge of materials engineering success is our foundational scientific research, which provides us with knowledge and capabilities that

  2. A New Culture of Assessment: Preliminary Report on the ARL SERVQUAL Survey.

    Science.gov (United States)

    Cook, Colleen; Heath, Fred; Thompson, Bruce

    Texas A&M University and the Association of Research Libraries (ARL) under the New Measures initiative are engaged in a project to evaluate service quality in research libraries using an augmented SERVQUAL instrument. In spring 2000, 13 ARL libraries in North America invited a random sample of students and faculty to take the survey through…

  3. Korogwe Research Laboratory

    DEFF Research Database (Denmark)

    Knudsen, Jakob

    2012-01-01

    . It is a large vaccine trial programme simultaneously conducted in several countries in Africa funded by the Bill and Melinda Gates Foundation. The laboratory is an extension to a district hospital placed quite isolated and rural in the north-eastern part of Tanzania. It’s close to the equator and the climate...... and ceiling have been separated leaving a large space for natural ventilation creating a general chimney effect. To provide independent backup water supply all rainwater falling on the roof is collected and directed through a sand filter into a 100m3 subterranean water tank. All constructions, details...... and materials have been carefully selected to last a long time even in a future situation with limited maintenance. Except from the high-end lab equipment only local available materials have been used. All major spaces are reached from colonnades surrounding an inner calm and cool garden space equipped...

  4. Physical Research Laboratory

    Indian Academy of Sciences (India)

    Studies on star formation processes, active galaxies, BL Lac objects and ... photospheric and chromospheric studies and observations for the international GONG ... Research in computer science with focus on image processing and.

  5. Great Lakes Environmental Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — NOAA-GLERL and its partners conduct innovative research on the dynamic environments and ecosystems of the Great Lakes and coastal regions to provide information for...

  6. Research System Integration Laboratory (SIL)

    Data.gov (United States)

    Federal Laboratory Consortium — The VEA Research SIL (VRS) is essential to the success of the TARDEC 30-Year Strategy. The vast majority of the TARDEC Capability Sets face challenging electronics...

  7. Research laboratories annual report 1991

    International Nuclear Information System (INIS)

    1992-08-01

    The 1990-1991 activities, of the Israel Atomic Energy Commission's research laboratories, are presented in this report. The main fields of interest are chemistry and material sciences, life and environmental sciences, nuclear physics and technology

  8. Research@ARL: Network Sciences

    Science.gov (United States)

    2013-03-01

    function in concert. Consider the behavior of social insects, such as bees and ants. Fish and birds are other examples of animals whose collective...Tropical Watershed, Springer/Kluwer, 83–95, 2005. Lehner, B. and Döll, P.: Development and validation of a global database of lakes, reservoirs and wetlands ...what it would be in an unperturbed network. A biological network with this sensitivity to error would not survive for very long in the wild . For

  9. Research@ARL: Energy & Energetics

    Science.gov (United States)

    2012-06-01

    LiNi0.80Co0.15Al0.05O2 ( NCA ), cathode in a full cell, we found that the activation energy, Ea, for the charge transfer at the graphite/electrolyte interface...kinetics at the graphite anode and the lithium nickel cobalt aluminum oxide, LiNi0.80Co0.15Al0.05O2 ( NCA ), cathode in a full cell, we found that the...Both the NCA and the graphite electrodes are porous electrodes. The dimension of the NCA cathode was 6.35 cm × 3.81 cm, the dimension of the graphite

  10. An overview of the U.S. Army Research Laboratory's Sensor Information Testbed for Collaborative Research Environment (SITCORE) and Automated Online Data Repository (AODR) capabilities

    Science.gov (United States)

    Ward, Dennis W.; Bennett, Kelly W.

    2017-05-01

    The Sensor Information Testbed COllaberative Research Environment (SITCORE) and the Automated Online Data Repository (AODR) are significant enablers of the U.S. Army Research Laboratory (ARL)'s Open Campus Initiative and together create a highly-collaborative research laboratory and testbed environment focused on sensor data and information fusion. SITCORE creates a virtual research development environment allowing collaboration from other locations, including DoD, industry, academia, and collation facilities. SITCORE combined with AODR provides end-toend algorithm development, experimentation, demonstration, and validation. The AODR enterprise allows the U.S. Army Research Laboratory (ARL), as well as other government organizations, industry, and academia to store and disseminate multiple intelligence (Multi-INT) datasets collected at field exercises and demonstrations, and to facilitate research and development (R and D), and advancement of analytical tools and algorithms supporting the Intelligence, Surveillance, and Reconnaissance (ISR) community. The AODR provides a potential central repository for standards compliant datasets to serve as the "go-to" location for lessons-learned and reference products. Many of the AODR datasets have associated ground truth and other metadata which provides a rich and robust data suite for researchers to develop, test, and refine their algorithms. Researchers download the test data to their own environments using a sophisticated web interface. The AODR allows researchers to request copies of stored datasets and for the government to process the requests and approvals in an automated fashion. Access to the AODR requires two-factor authentication in the form of a Common Access Card (CAC) or External Certificate Authority (ECA)

  11. Accessing Digital Libraries: A Study of ARL Members' Digital Projects

    Science.gov (United States)

    Kahl, Chad M.; Williams, Sarah C.

    2006-01-01

    To ensure efficient access to and integrated searching capabilities for their institution's new digital library projects, the authors studied Web sites of the Association of Research Libraries' (ARL) 111 academic, English-language libraries. Data were gathered on 1117 digital projects, noting library Web site and project access, metadata, and…

  12. Flexible Work Arrangements in ARL Libraries. SPEC Kit #180.

    Science.gov (United States)

    Zabel, Diane, Comp.; And Others

    This report presents the results of a survey of Association of Research Libraries (ARL) members about the current climate and practices regarding flexible work arrangements. Data are reported on the availability of schedule flexibility, job exchange, part-time arrangements, and leaves, as well as information about faculty status, tenure,…

  13. Travel Policies in ARL Libraries. SPEC Kit 161.

    Science.gov (United States)

    Cramer, Michael D.

    This kit examines the methods and policies currently used to provide travel funding for academic librarians. The results of a survey of Association of Research Libraries (ARL) libraries (n=73) conducted in Fall 1989 are presented as well as examples of travel policies and guidelines submitted by the following respondents: the Universities of…

  14. The Imperative for Diversity: ARL's Progress and Role

    Science.gov (United States)

    Dewey, Barbara I.

    2009-01-01

    The Association of Research Libraries' diversity initiatives, under the leadership of Duane Webster and member libraries, have had a visible and long-lasting influence on the makeup of academic librarianship. ARL's accomplishments and progress in advancing diversity comprise important milestones for librarianship and did not come without…

  15. Evaluation and Application of the Weather Research and Forecast Model

    National Research Council Canada - National Science Library

    Passner, Jeffrey E

    2007-01-01

    ... by the U.S. Army Research Laboratory (ARL) to determine how accurate and robust the model is under a variety of meteorological conditions, with an emphasis on fine resolution, short-range forecasts in complex terrain...

  16. Small-Engine Research Laboratory (SERL)

    Data.gov (United States)

    Federal Laboratory Consortium — Description: The Small-Engine Research Laboratory (SERL) is a facility designed to conduct experimental small-scale propulsion and power generation systems research....

  17. Army Plasma/Propellant Interaction Workshop - U.S. Army Research Office, 17-18 November 1998

    National Research Council Canada - National Science Library

    Shaw, Robert

    1999-01-01

    .... Army Research Laboratory (ARL)-ARO effort to develop a coordinated research program to address the needs of advanced gun propulsion, in particular, in the application of plasmas as ignition and energy augmentation sources...

  18. Laboratory directed research and development

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-15

    The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory's R D capabilities, and further the development of its strategic initiatives. Among the aims of the projects supported by the Program are establishment of engineering proof-of-principle''; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these project are closely associated with major strategic thrusts of the Laboratory as described in Argonne's Five Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne. Areas of emphasis are (1) advanced accelerator and detector technology, (2) x-ray techniques in biological and physical sciences, (3) advanced reactor technology, (4) materials science, computational science, biological sciences and environmental sciences. Individual reports summarizing the purpose, approach, and results of projects are presented.

  19. Physics Research at the Naval Research Laboratory

    Science.gov (United States)

    Coffey, Timothy

    2001-03-01

    The United States Naval Research Laboratory conducts a broad program of research into the physical properties of matter. Studies range from low temperature physics, such as that associated with superconducting systems to high temperature systems such as laser produced or astrophysical plasmas. Substantial studies are underway on surface science and nanoscience. Studies are underway on the electronic and optical properties of materials. Studies of the physical properties of the ocean and the earth’s atmosphere are of considerable importance. Studies of the earth’s sun particularly as it effects the earth’s ionosphere and magnetosphere are underway. The entire program involves a balance of laboratory experiments, field experiments and supporting theoretical and computational studies. This talk will address NRL’s funding of physics, its employment of physicists and will illustrate the nature of NRL’s physics program with several examples of recent accomplishments.

  20. NAS Human Factors Safety Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory conducts an integrated program of research on the relationship of factors concerning individuals, work groups, and organizations as employees perform...

  1. US Army Research Laboratory (ARL) Standard for Characterization of Electric-Field Sensors, 10 Hz to 10 kHz

    Science.gov (United States)

    2016-11-01

    A third method of sensing quasi-static fields is to use ground reference sensors (GRSs), where 2 conductors are connected through a transimpedance ... amplifier to measure dE/dt as a function of dq/dt on the source conductor relative to the sink conductor.3 Sensors using the second and third...software. In most of our experiments, it is used to interface between the PXIe 1062Q and the waveform generator only. A current to voltage amplifier

  2. CERN at Arles: LHC featured in prestigious photography festival

    CERN Multimedia

    Jordan Juras

    2011-01-01

    Six photographs of the LHC experiment are being featured in this year’s Rencontres d’Arles photography festival. Simon Norfolk’s series, The LHC: the spirit of enquiry, was chosen as part of an exhibition celebrating 30 years of photography at the New York Times Magazine.   Simon Norfolk’s series "The LHC: the spirit of enquiry" on display at the Rencontres d'Arles festival. The photographs were originally taken in October 2006, when Norfolk was sent on an assignment to a ‘little known’ laboratory in Switzerland. “When I came to CERN, nobody I knew had ever heard of the place,” explains Norfolk. “Everybody I spoke to when I came back said, ‘You’ve been where? You’ve done what?’” Kathy Ryan, New York Times Magazine photo editor, sent Norfolk to ‘capture something new’. He describes Ryan’s assignments...

  3. NDE Acoustic Microscopy Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The purpose is to develop advanced, more effective high-resolution micro-NDE materials characterization methods using scanning acoustic microscopy. The laboratory's...

  4. Fuel Combustion Laboratory | Transportation Research | NREL

    Science.gov (United States)

    Fuel Combustion Laboratory Fuel Combustion Laboratory NREL's Fuel Combustion Laboratory focuses on designs, using both today's technology and future advanced combustion concepts. This lab supports the combustion chamber platform for fuel ignition kinetics research, was acquired to expand the lab's

  5. Institute of Laboratory Animal Research

    National Research Council Canada - National Science Library

    Dell, Ralph

    2000-01-01

    ...; and reports on specific issues of humane care and use of laboratory animals. ILAR's mission is to help improve the availability, quality, care, and humane and scientifically valid use of laboratory animals...

  6. Biometrics Research and Engineering Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — As the Department of Defense moves forward in its pursuit of integrating biometrics technology into facility access control, the Global War on Terrorism and weapon...

  7. Subsonic Aerodynamic Research Laboratory (SARL)

    Data.gov (United States)

    Federal Laboratory Consortium — Description: The SARL is a unique high contraction, open circuit subsonic wind tunnel providing a test velocity up to 436 mph (0.5 Mach number) and a high quality,...

  8. Techniques in cancer research: a laboratory manual

    International Nuclear Information System (INIS)

    Deo, M.G.; Seshadri, R.; Mulherkar, R.; Mukhopadhyaya, R.

    1995-01-01

    Cancer Research Institute (CRI) works on all facets of cancer using the latest biomedical tools. For this purpose, it has established modern laboratories in different branches of cancer biology such as cell and molecular biology, biochemistry, immunology, chemical and viral oncogenesis, genetics of cancer including genetic engineering, tissue culture, cancer chemotherapy, neurooncology and comparative oncology. This manual describes the protocols used in these laboratories. There is also a chapter on handling and care of laboratory animals, an essential component of any modern cancer biology laboratory. It is hoped that the manual will be useful to biomedical laboratories, specially those interested in cancer research. refs., tabs., figs

  9. Naval Research Laboratory Arctic Initiatives

    Science.gov (United States)

    2011-06-01

    Campaign Code 7420 Arctic Modeling Code 7320/7500/7600 In-situ NRL, CRREL NRL boreholes Strategy Remote Sensing Synergism −Collect in-situ...Navy and Marine Corps Corporate Laboratory An array of BMFCs being prepared for deployment. Each BMFC consists of a weighted anode laid flat onto...Gas CH4 E C D CO2 BGHS Free Methane Gas Hydrates HCO3- HCO3- Seismic and geochemical data to predict deep sediment hydrates Estimate spatial

  10. Laboratory Animal Technician | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused

  11. Argonne Research Library | Argonne National Laboratory

    Science.gov (United States)

    Argonne Argonne Research Library The Argonne Research Library supports the scientific and technical research needs of Argonne National Laboratory employees. Our library catalog is available via the Research questions or concerns, please contact us at librarians@anl.gov. Contact the Library Argonne Research Library

  12. Sandia National Laboratories: Research: Biodefense

    Science.gov (United States)

    Energy Stationary Power Earth Science Transportation Energy Energy Research Global Security WMD knowledge to counter disease Sandia conducts research into how pathogens interact and subvert a host's immune response to develop the knowledge base needed to create new novel environmental detectors, medical

  13. Research and Progress on Virtual Cloud Laboratory

    Directory of Open Access Journals (Sweden)

    Zhang Jian Wei

    2016-01-01

    Full Text Available In recent years, cloud computing technology has experienced continuous development and improvement, and has gradually expanded to the education sector. First, this paper will introduce the background knowledge of the current virtual cloud laboratory; by comparing the advantages and disadvantages between traditional laboratory and virtual cloud laboratory, and comparing the application, advantages and disadvantages, and development trend of OpenStack technology and VMWare technology in safety, performance, design, function, use case, and value of virtual cloud laboratory, this paper concludes that application based on OpenStack virtual cloud laboratory in universities and research institutes and other departments is essential.

  14. Research laboratories annual report 1994

    International Nuclear Information System (INIS)

    1996-01-01

    The publication is the 1994 annual report of the Israel atomic energy commission in a new format. The report includes three invited papers and a bibliographic list of publications by the commission scientific researches

  15. Research laboratories annual report 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    The publication is the 1994 annual report of the Israel atomic energy commission in a new format. The report includes three invited papers and a bibliographic list of publications by the commission scientific researches.

  16. Naval Research Laboratory 1986 Review

    Science.gov (United States)

    1986-01-01

    probabil- infinitesimal impedance elements cannot be dep- ity density, icted .) If PR (r. 1 is the joint probability den- sity function for r and 1, a...Dynamics. 1-5 Sept. 1986, finse Research. Medellin , Colombia. % Rosenblum, L.J., Chairperson, IEEE Computer Saks, N.S., Coorganizer and lecturer, IEEE

  17. Research laboratories annual report 1992

    International Nuclear Information System (INIS)

    1993-07-01

    The report book presents the various research activities within the Israel Atomic Energy Commission, during 1992 calendar year. The discipline reported here are (by chapters): theoretical physics and theoretical chemistry, optics and lasers, solid states and nuclear physics, material sciences, chemistry, radiopharmaceuticals, labelled compounds and environmental studies, radiation effects, dosimetry and protection, instrumentation and techniques

  18. Optimization of In-Cylinder Pressure Filter for Engine Research

    Science.gov (United States)

    2017-06-01

    ARL-TR-8034 ● JUN 2017 US Army Research Laboratory Optimization of In-Cylinder Pressure Filter for Engine Research by Kenneth...Laboratory Optimization of In-Cylinder Pressure Filter for Engine Research by Kenneth S Kim, Michael T Szedlmayer, Kurt M Kruger, and Chol-Bum M...

  19. Sandia National Laboratories: Research: Research Foundations: Nanodevices

    Science.gov (United States)

    Technology Partnerships Business, Industry, & Non-Profits Government Universities Center for Mexico Small Business Assistance Program Sandia Science & Technology Park Careers Community support for research; technology advancement and maturation; and small-lot, fast-turn prototyping Our

  20. Research laboratories annual report 1993

    International Nuclear Information System (INIS)

    1994-08-01

    The 1993 annual report of the Israel Atomic Energy Commission presents, in brief and concise form, recent results and achievements of the well established program of the basic and applied research carried out by the scientists and engineers of the Israel Atomic Energy Commission in collaboration with colleagues at the other institutions in Israel and abroad. In terms of contents, the report presents the usual combination of topical basic applied research. Much of the work has been published or submitted for publication in the international scientific or technical literature. The main headings in the report are: theoretical physics and theoretical chemistry; optics and lasers; solid states and nuclear physics; materials sciences; chemistry; environmental studies and radiopharmaceuticals; radiation effects, dosimetry and radioprotection; and instrumentation and techniques

  1. Research laboratories annual report 1987

    International Nuclear Information System (INIS)

    1988-08-01

    The 1987 report reflects a continuation of trends and patterns established in previous years. It does not reveal novel revolutionary developments and does not open new horizons and vistas. Rather, the report represents what we believe is a sound and mature program striving to achieve a proper balance between innovative basic research and economically viable practical applications. In the field of nuclear power, six entries are devoted to an analysis of the economics, safety and vulnerability of HTGR's. Theoretical work on more advanced concepts of hybrid and fusion reactors, is also a part of our research program. In plasma physics, the highly innovative applied topic of electrothermal propulsion was added to the more familiar research on laser induced plasmas and use of cool, low density plasmas to produce coatings and other thin layers of refractory materials. Results from the airborne radiometric survey carried out in collaboration with the Geological Survey of Israel and some of the techniques developed for this purpose are shown here for the first time. Of particular interest are the anomalies found in the Gevanim Valley in the Machtesh Ramon area and their interpretation. Noteworthy achievements in radiopharmaceutics include the development of a new improved 99 Mo/ 99m Tc generator and successful clinical tests of the innovative generator of ultrashort-lived 191m Ir. The food irradiation program has reached the stage of true commercial implementation: over 50 tons of spices and condiments were treated for the food industry in 1987. In the field of non-nuclear applications, important achievements were attained in the development of surgical holmium solid state lasers and their application to gastroenterology, cardiac and vascular surgery, urology, neurosurgery and other disciplines

  2. Laboratory research in homeopathy: pro.

    Science.gov (United States)

    Khuda-Bukhsh, Anisur R

    2006-12-01

    Homeopathy is a holistic method of treatment that uses ultralow doses of highly diluted natural substances originating from plants, minerals, or animals and is based on the principle of "like cures like." Despite being occasionally challenged for its scientific validity and mechanism of action, homeopathy continues to enjoy the confidence of millions of patients around the world who opt for this mode of treatment. Contrary to skeptics' views, research on home-opathy using modern tools mostly tends to support its efficacy and advocates new ideas toward understanding its mechanism of action. As part of a Point-Counterpoint feature, this review and its companion piece in this issue by Moffett et al (Integr Cancer Ther. 2006;5:333-342) are composed of a thesis section, a response section in reaction to the companion thesis, and a rebuttal section to address issues raised in the companion response.

  3. Laboratory Directed Research ampersand Development Program

    International Nuclear Information System (INIS)

    Ogeka, G.J.; Romano, A.J.

    1993-12-01

    At Brookhaven National Laboratory the Laboratory Directed Research and Development (LDRD) Program is a discretionary research and development tool critical in maintaining the scientific excellence and vitality of the laboratory. It is also a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor in achieving and maintaining staff excellence, and a means to address national needs, within the overall mission of the Department of Energy and Brookhaven National Laboratory. This report summarizes research which was funded by this program during fiscal year 1993. The research fell in a number of broad technical and scientific categories: new directions for energy technologies; global change; radiation therapies and imaging; genetic studies; new directions for the development and utilization of BNL facilities; miscellaneous projects. Two million dollars in funding supported 28 projects which were spread throughout all BNL scientific departments

  4. Location | Frederick National Laboratory for Cancer Research

    Science.gov (United States)

    The Frederick National Laboratory for Cancer Research campus is located 50 miles northwest of Washington, D.C., and 50 miles west of Baltimore, Maryland, in Frederick, Maryland. Satellite locations include leased and government facilities extending s

  5. Safe handling of plutonium in research laboratories

    International Nuclear Information System (INIS)

    1976-01-01

    The training film illustrates the main basic requirements for the safe handling of small amounts of plutonium. The film is intended not only for people setting up plutonium research laboratories but also for all those who work in existing plutonium research laboratories. It was awarded the first prize in the category ''Protection of Workers'' at the international film festival organized by the 4th World Congress of the International Radiation Protection Association (IRPA) in Paris in April 1977

  6. Safe handling of plutonium in research laboratories

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1977-12-31

    The training film illustrates the main basic requirements for the safe handling of small amounts of plutonium. The film is intended not only for people setting up plutonium research laboratories but also for all those who work in existing plutonium research laboratories. It was awarded the first prize in the category ``Protection of Workers`` at the international film festival organized by the 4th World Congress of the International Radiation Protection Association (IRPA) in Paris in April 1977

  7. Chemical research at Argonne National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    Argonne National Laboratory is a research and development laboratory located 25 miles southwest of Chicago, Illinois. It has more than 200 programs in basic and applied sciences and an Industrial Technology Development Center to help move its technologies to the industrial sector. At Argonne, basic energy research is supported by applied research in diverse areas such as biology and biomedicine, energy conservation, fossil and nuclear fuels, environmental science, and parallel computer architectures. These capabilities translate into technological expertise in energy production and use, advanced materials and manufacturing processes, and waste minimization and environmental remediation, which can be shared with the industrial sector. The Laboratory`s technologies can be applied to help companies design products, substitute materials, devise innovative industrial processes, develop advanced quality control systems and instrumentation, and address environmental concerns. The latest techniques and facilities, including those involving modeling, simulation, and high-performance computing, are available to industry and academia. At Argonne, there are opportunities for industry to carry out cooperative research, license inventions, exchange technical personnel, use unique research facilities, and attend conferences and workshops. Technology transfer is one of the Laboratory`s major missions. High priority is given to strengthening U.S. technological competitiveness through research and development partnerships with industry that capitalize on Argonne`s expertise and facilities. The Laboratory is one of three DOE superconductivity technology centers, focusing on manufacturing technology for high-temperature superconducting wires, motors, bearings, and connecting leads. Argonne National Laboratory is operated by the University of Chicago for the U.S. Department of Energy.

  8. NASA Ames Fluid Mechanics Laboratory research briefs

    Science.gov (United States)

    Davis, Sanford (Editor)

    1994-01-01

    The Ames Fluid Mechanics Laboratory research program is presented in a series of research briefs. Nineteen projects covering aeronautical fluid mechanics and related areas are discussed and augmented with the publication and presentation output of the Branch for the period 1990-1993.

  9. Perspectives on...Special Collections at ARL Libraries and K-12 Outreach: Current Trends

    Science.gov (United States)

    Visser, Michelle

    2006-01-01

    This article examines the results of a survey sent to Association of Research Libraries (ARL) Special Collections requesting information on outreach to K-12 students. Over half of the respondents work with K-12 and many of those who currently do not are planning to. New pressures and changing philosophies contribute to this trend.

  10. Salary Compression: A Time-Series Ratio Analysis of ARL Position Classifications

    Science.gov (United States)

    Seaman, Scott

    2007-01-01

    Although salary compression has previously been identified in such professional schools as engineering, business, and computer science, there is now evidence of salary compression among Association of Research Libraries members. Using salary data from the "ARL Annual Salary Survey", this study analyzes average annual salaries from 1994-1995…

  11. ARL Physics Web Pages: An Evaluation by Established, Transitional and Emerging Benchmarks.

    Science.gov (United States)

    Duffy, Jane C.

    2002-01-01

    Provides an overview of characteristics among Association of Research Libraries (ARL) physics Web pages. Examines current academic Web literature and from that develops six benchmarks to measure physics Web pages: ease of navigation; logic of presentation; representation of all forms of information; engagement of the discipline; interactivity of…

  12. Idaho National Laboratory Research & Development Impacts

    Energy Technology Data Exchange (ETDEWEB)

    Stricker, Nicole [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-01-01

    Technological advances that drive economic growth require both public and private investment. The U.S. Department of Energy’s national laboratories play a crucial role by conducting the type of research, testing and evaluation that is beyond the scope of regulators, academia or industry. Examples of such work from the past year can be found in these pages. Idaho National Laboratory’s engineering and applied science expertise helps deploy new technologies for nuclear energy, national security and new energy resources. Unique infrastructure, nuclear material inventory and vast expertise converge at INL, the nation’s nuclear energy laboratory. Productive partnerships with academia, industry and government agencies deliver high-impact outcomes. This edition of INL’s Impacts magazine highlights national and regional leadership efforts, growing capabilities, notable collaborations, and technology innovations. Please take a few minutes to learn more about the critical resources and transformative research at one of the nation’s premier applied science laboratories.

  13. 1999 LDRD Laboratory Directed Research and Development

    Energy Technology Data Exchange (ETDEWEB)

    Rita Spencer; Kyle Wheeler

    2000-06-01

    This is the FY 1999 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5) engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.

  14. Laboratory and cyclotron requirements for PET research

    International Nuclear Information System (INIS)

    Schlyer, D.J.

    1993-01-01

    The requirements for carrying out PET research can vary widely depending on the type of basic research being carried out and the extent of a clinical program at a particular center. The type of accelerator and laboratory facilities will, of course, depend on the exact mix. These centers have been divided into four categories. 1. Clinical PET with no radionuclide production facilities, 2. clinical PET with some radionuclide production facilities, 3. clinical PET with research support, and 4. a PET research facility developing new tracers and exploring clinical applications. Guidelines for the choice of an accelerator based on these categories and the practical yields of the common nuclear reactions for production of PET isotopes have been developed and are detailed. Guidelines as to the size and physical layout of the laboratory space necessary for the synthesis of various radiopharmaceuticals have also been developed and are presented. Important utility and air flow considerations are explored

  15. Occupational radiation exposures in research laboratories

    International Nuclear Information System (INIS)

    Vaccari, S.; Papotti, E.; Pedrazzi, G.

    2006-01-01

    Radioactive sources are widely used in many research activities at University centers. In particular, the activities concerning use of sealed form ( 57 Co in Moessbauer application) and unsealed form ( 3 H, 14 C, 32 P in radioisotope laboratories) are analyzed. The radiological impact of these materials and potential effective doses to researchers and members of the public were evaluated to show compliance with regulatory limits. A review of the procedures performed by researchers and technicians in the research laboratories with the relative dose evaluations is presented in different situations, including normal operations and emergency situations, for example the fire. A study of the possible exposure to radiation by workers, restricted groups of people, and public in general, as well as environmental releases, is presented. (authors)

  16. Occupational radiation exposures in research laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Vaccari, S.; Papotti, E. [Parma Univ., Health Physics (Italy); Pedrazzi, G. [Parma Univ., Dept. of Public Health (Italy)

    2006-07-01

    Radioactive sources are widely used in many research activities at University centers. In particular, the activities concerning use of sealed form ({sup 57}Co in Moessbauer application) and unsealed form ({sup 3}H, {sup 14}C, {sup 32}P in radioisotope laboratories) are analyzed. The radiological impact of these materials and potential effective doses to researchers and members of the public were evaluated to show compliance with regulatory limits. A review of the procedures performed by researchers and technicians in the research laboratories with the relative dose evaluations is presented in different situations, including normal operations and emergency situations, for example the fire. A study of the possible exposure to radiation by workers, restricted groups of people, and public in general, as well as environmental releases, is presented. (authors)

  17. National Renewable Energy Laboratory 2004 Research Review

    Energy Technology Data Exchange (ETDEWEB)

    2005-03-01

    In-depth articles on several NREL technologies and advances, including: aligning quantum dots and related nanoscience and nanotechnology research; using NREL's Advanced Automotive Manikin (ADAM) to help test and design ancillary automotive systems; and harvesting ocean wind to generate electricity with deep-water wind turbines. Also covered are NREL news, research updates, and awards and honors received by the Laboratory.

  18. Mobile robotics research at Sandia National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Morse, W.D.

    1998-09-01

    Sandia is a National Security Laboratory providing scientific and engineering solutions to meet national needs for both government and industry. As part of this mission, the Intelligent Systems and Robotics Center conducts research and development in robotics and intelligent machine technologies. An overview of Sandia`s mobile robotics research is provided. Recent achievements and future directions in the areas of coordinated mobile manipulation, small smart machines, world modeling, and special application robots are presented.

  19. Research laboratories annual report. 1973 and 1974

    International Nuclear Information System (INIS)

    1975-02-01

    This report presents brief summaries of the research carried out at the Israel A.E.C. laboratories during the two years 1973 and 1974 in the following fields: theoretical physics and chemistry, neutron and reactor physics, solid state physics and metallurgy, laser-induced plasma research, nuclear physics and chemistry, radiation chemistry and applications of radiation and radioisotopes, physical and inorganic chemistry, analytical chemistry, health physics, environmental studies, instrumentation and techniques. (B.G.)

  20. Virtual laboratory for fusion research in Japan

    International Nuclear Information System (INIS)

    Tsuda, K.; Nagayama, Y.; Yamamoto, T.; Horiuchi, R.; Ishiguro, S.; Takami, S.

    2008-01-01

    A virtual laboratory system for nuclear fusion research in Japan has been developed using SuperSINET, which is a super high-speed network operated by National Institute of Informatics. Sixteen sites including major Japanese universities, Japan Atomic Energy Agency and National Institute for Fusion Science (NIFS) are mutually connected to SuperSINET with the speed of 1 Gbps by the end of 2006 fiscal year. Collaboration categories in this virtual laboratory are as follows: the large helical device (LHD) remote participation; the remote use of supercomputer system; and the all Japan ST (Spherical Tokamak) research program. This virtual laboratory is a closed network system, and is connected to the Internet through the NIFS firewall in order to keep higher security. Collaborators in a remote station can control their diagnostic devices at LHD and analyze the LHD data as they were at the LHD control room. Researchers in a remote station can use the supercomputer of NIFS in the same environment as NIFS. In this paper, we will describe detail of technologies and the present status of the virtual laboratory. Furthermore, the items that should be developed in the near future are also described

  1. Laboratory Directed Research and Development Program

    Energy Technology Data Exchange (ETDEWEB)

    Ogeka, G.J.

    1991-12-01

    Today, new ideas and opportunities, fostering the advancement of technology, are occurring at an ever-increasing rate. It, therefore, seems appropriate that a vehicle be available which fosters the development of these new ideas and technologies, promotes the early exploration and exploitation of creative and innovative concepts, and which develops new fundable'' R D projects and programs. At Brookhaven National Laboratory (BNL), one such method is through its Laboratory Directed Research and Development (LDRD) Program. This discretionary research and development tool is critical in maintaining the scientific excellence and vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor achieving and maintaining staff excellence, and a means to address national needs, with the overall mission of the Department of Energy (DOE) and the Brookhaven National Laboratory. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, they have resulted in numerous publications in various professional and scientific journals, and presentations at meetings and forums.

  2. Laboratory research irradiators with enhanced security features

    International Nuclear Information System (INIS)

    Srivastava, Piyush

    2016-01-01

    Over the years BRIT has developed state of art technology for laboratory research irradiators which are suited most for carrying out research and development works in the fields of radiation processing. These equipment which house radioactive sources up to 14 kCi are having a number of features to meet users requirements. They are manufactured as per the national and International standards of safety codes. The paper deals with design, development and application aspects of laboratory research irradiator called Gamma Chamber and also the new security features planned for incorporation in the equipment. Equipment are being regularly manufactured, supplied and installed by BRIT in India and Abroad. There is a number of such equipment in use at different institutions and are found to be very useful. (author)

  3. Laboratory research irradiators with enhanced security features

    International Nuclear Information System (INIS)

    Srivastava, Piyush

    2014-01-01

    Over the years BRIT has developed state of art technology for laboratory research irradiators which are suited most for carrying out research and development works in the fields of radiation processing. These equipment which house radioactive sources up to 14 kCi are having a number of features to meet users requirements. They are manufactured as per the national and International standards of safety codes. The paper deals with design, development and application aspects of laboratory research irradiator called Gamma Chamber and also the new security features planned for incorporation in the equipment. Equipment are being regularly manufactured, supplied and installed by BRIT in India and Abroad. There are a number of such equipment in use at different institutions and are found to be very useful. (author)

  4. Catching the Cyber Spy: ARL's Interrogator

    National Research Council Canada - National Science Library

    Long, Kerry S

    2004-01-01

    The U.S. Army Research Laboratory has designed a network-based intrusion detection framework, Interrogator, which addresses the constantly changing threat environment that Department of Defense networks...

  5. Laboratory Directed Research and Development FY 2000

    International Nuclear Information System (INIS)

    Hansen, Todd; Levy, Karin

    2001-01-01

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Annual report on Laboratory Directed Research and Development for FY2000

  6. Laboratory Directed Research and Development FY 2000

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd; Levy, Karin

    2001-02-27

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Annual report on Laboratory Directed Research and Development for FY2000.

  7. Laboratory Directed Research and Development Program

    International Nuclear Information System (INIS)

    1994-02-01

    This report is compiled from annual reports submitted by principal investigators following the close of fiscal year 1993. This report describes the projects supported and summarizes their accomplishments. The program advances the Laboratory's core competencies, foundations, scientific capability, and permits exploration of exciting new opportunities. Reports are given from the following divisions: Accelerator and Fusion Research, Chemical Sciences, Earth Sciences, Energy and Environment, Engineering, Environment -- Health and Safety, Information and Computing Sciences, Life Sciences, Materials Sciences, Nuclear Science, Physics, and Structural Biology

  8. Laboratory directed research and development FY91

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, S.E.; Hedman, I.; Kirvel, R.D.; McGregor, C.K. (eds.)

    1991-01-01

    This review of research programs at Lawrence Livermore National Laboratory is composed of individual papers on various subjects. Broad topics of interest are: chemistry and materials science, computation, earth sciences, engineering, nuclear physics, and physics, and biology. Director's initiatives include the development of a transgenic mouse, accelerator mass spectrometry, high-energy physics detectors, massive parallel computing, astronomical telescopes, the Kuwaiti oil fires and a compact torus accelerator. (GHH)

  9. Laboratory directed research and development FY91

    International Nuclear Information System (INIS)

    Anderson, S.E.; Hedman, I.; Kirvel, R.D.; McGregor, C.K.

    1991-01-01

    This review of research programs at Lawrence Livermore National Laboratory is composed of individual papers on various subjects. Broad topics of interest are: chemistry and materials science, computation, earth sciences, engineering, nuclear physics, and physics, and biology. Director's initiatives include the development of a transgenic mouse, accelerator mass spectrometry, high-energy physics detectors, massive parallel computing, astronomical telescopes, the Kuwaiti oil fires and a compact torus accelerator

  10. National Renewable Energy Laboratory 2003 Research Review

    Energy Technology Data Exchange (ETDEWEB)

    2004-04-01

    In-depth articles on several NREL technologies and advances, including: production of hydrogen using renewable resources and technologies; use of carbon nanotubes for storing hydrogen; enzymatic reduction of cellulose to simple sugars as a platform for making fuel, chemicals, and materials; and the potential of electricity from wind energy to offset carbon dioxide emissions. Also covered are NREL news, awards and honors received by the Laboratory, and patents granted to NREL researchers.

  11. Laboratory-directed research and development

    International Nuclear Information System (INIS)

    Gerstl, S.A.W.; Caughran, A.B.

    1992-05-01

    This report summarizes progress from the Laboratory-Directed Research and Development (LDRD) program during fiscal year 1991. In addition to a programmatic and financial overview, the report includes progress reports from 230 individual R ampersand D projects in 9 scientific categories: atomic and molecular physics; biosciences; chemistry; engineering and base technologies; geosciences; space sciences, and astrophysics; materials sciences; mathematics and computational sciences; nuclear and particle physics; and plasmas, fluids, and particle beams

  12. MSU-DOE Plant Research Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    This document is the compiled progress reports of research funded through the Michigan State University/Department of Energy Plant Research Laboratory. Fourteen reports are included, covering the molecular basis of plant/microbe symbiosis, cell wall biosynthesis and proteins, gene expression, stress responses, plant hormone biosynthesis, interactions between the nuclear and organelle genomes, sensory transduction and tropisms, intracellular sorting and trafficking, regulation of lipid metabolism, molecular basis of disease resistance and plant pathogenesis, developmental biology of Cyanobacteria, and hormonal involvement in environmental control of plant growth. 320 refs., 26 figs., 3 tabs. (MHB)

  13. Hazardous waste management in research laboratories

    International Nuclear Information System (INIS)

    Sundstrom, G.

    1989-01-01

    Hazardous waste management in research laboratories benefits from a fundamentally different approach to the hazardous waste determination from industry's. This paper introduces new, statue-based criteria for identifying hazardous wastes (such as radiological mixed wastes and waste oils) and links them to a forward-looking compliance of laboratories, the overall system integrates hazardous waste management activities with other environmental and hazard communication initiatives. It is generalizable to other waste generators, including industry. Although only the waste identification and classification aspects of the system are outlined in detail here, four other components are defined or supported, namely: routine and contingency practices; waste treatment/disposal option definition and selection; waste minimization, recycling, reuse, and substitution opportunities; and key interfaces with other systems, including pollution prevention

  14. Master plan of Mizunami underground research laboratory

    International Nuclear Information System (INIS)

    1999-04-01

    In June 1994, the Atomic Energy Commission of Japan reformulated the Long-Term Programme for Research, Development and Utilisation of Nuclear Energy (LTP). The LTP (item 7, chapter 3) sets out the guidelines which apply to promoting scientific studies of the deep geological environment, with a view to providing a sound basis for research and development programmes for geological disposal projects. The Japan Nuclear Cycle Development Institute (JNC) has been conducting scientific studies of the deep geological environment as part of its Geoscientific Research Programme. The LTP also emphasised the importance of deep underground research facilities in the following terms: Deep underground research facilities play an important role in research relating to geological disposal. They allow the characteristics and features of the geological environment, which require to be considered in performance assessment of disposal systems, to be investigated in situ and the reliability of the models used for evaluating system performance to be developed and refined. They also provide opportunities for carrying out comprehensive research that will contribute to an improved overall understanding of Japan's deep geological environment. It is recommended that more than one facility should be constructed, considering the range of characteristics and features of Japan's geology and other relevant factors. It is important to plan underground research facilities on the basis of results obtained from research and development work already carried out, particularly the results of scientific studies of the deep geological environment. Such a plan for underground research facilities should be clearly separated from the development of an actual repository. JNC's Mizunami underground research laboratory (MIU) Project will be a deep underground research facility as foreseen by the above provisions of the LTP. (author)

  15. Idaho National Laboratory - Nuclear Research Center

    International Nuclear Information System (INIS)

    Zaidi, M.K.

    2005-01-01

    Full text: The Idaho National Laboratory is committed to the providing international nuclear leadership for the 21st Century, developing and demonstrating compiling national security technologies, and delivering excellence in science and technology as one of the United States Department of Energy's (DOE) multiprogram national laboratories. INL runs three major programs - Nuclear, Security and Science. nuclear programs covers the Advanced test reactor, Six Generation technology concepts selected for R and D, Targeting tumors - Boron Neutron capture therapy. Homeland security - Homeland Security establishes the Control System Security and Test Center, Critical Infrastructure Test Range evaluates technologies on a scalable basis, INL conducts high performance computing and visualization research and science - INL facility established for Geocentrifuge Research, Idaho Laboratory, a Utah company achieved major milestone in hydrogen research and INL uses extremophile bacteria to ease bleaching's environmental cost. To provide leadership in the education and training, INL has established an Institute of Nuclear Science and Engineering (Inset). The institute will offer a four year degree based on a newly developed curriculum - two year of basic science course work and two years of participation in project planning and development. The students enrolled in this program can continue to get a masters or a doctoral degree. This summer Inset is the host for the training of the first international group selected by the World Nuclear University (WNU) - 75 fellowship holders and their 30 instructors from 40 countries. INL has been assigned to provide future global leadership in the field of nuclear science and technology. Here, at INL, we keep safety first above all things and our logo is 'Nuclear leadership synonymous with safety leadership'

  16. National Renewable Energy Laboratory 2005 Research Review

    Energy Technology Data Exchange (ETDEWEB)

    Brown, H.; Gwinner, D.; Miller, M.; Pitchford, P.

    2006-06-01

    Science and technology are at the heart of everything we do at the National Renewable Energy Laboratory, as we pursue innovative, robust, and sustainable ways to produce energy--and as we seek to understand and illuminate the physics, chemistry, biology, and engineering behind alternative energy technologies. This year's Research Review highlights the Lab's work in the areas of alternatives fuels and vehicles, high-performing commercial buildings, and high-efficiency inverted, semi-mismatched solar cells.

  17. Research Opportunities at Storm Peak Laboratory

    Science.gov (United States)

    Hallar, A. G.; McCubbin, I. B.

    2006-12-01

    The Desert Research Institute (DRI) operates a high elevation facility, Storm Peak Laboratory (SPL), located on the west summit of Mt. Werner in the Park Range near Steamboat Springs, Colorado at an elevation of 3210 m MSL (Borys and Wetzel, 1997). SPL provides an ideal location for long-term research on the interactions of atmospheric aerosol and gas- phase chemistry with cloud and natural radiation environments. The ridge-top location produces almost daily transition from free tropospheric to boundary layer air which occurs near midday in both summer and winter seasons. Long-term observations at SPL document the role of orographically induced mixing and convection on vertical pollutant transport and dispersion. During winter, SPL is above cloud base 25% of the time, providing a unique capability for studying aerosol-cloud interactions (Borys and Wetzel, 1997). A comprehensive set of continuous aerosol measurements was initiated at SPL in 2002. SPL includes an office-type laboratory room for computer and instrumentation setup with outside air ports and cable access to the roof deck, a cold room for precipitation and cloud rime ice sample handling and ice crystal microphotography, a 150 m2 roof deck area for outside sampling equipment, a full kitchen and two bunk rooms with sleeping space for nine persons. The laboratory is currently well equipped for aerosol and cloud measurements. Particles are sampled from an insulated, 15 cm diameter manifold within approximately 1 m of its horizontal entry point through an outside wall. The 4 m high vertical section outside the building is capped with an inverted can to exclude large particles.

  18. Laboratory Directed Research and Development FY 1992

    Energy Technology Data Exchange (ETDEWEB)

    Struble, G.L.; Middleton, C.; Anderson, S.E.; Baldwin, G.; Cherniak, J.C.; Corey, C.W.; Kirvel, R.D.; McElroy, L.A. [eds.

    1992-12-31

    The Laboratory Directed Research and Development (LDRD) Program at Lawrence Livermore National Laboratory (LLNL) funds projects that nurture and enrich the core competencies of the Laboratory. The scientific and technical output from the FY 1992 RD Program has been significant. Highlights include (1) Creating the first laser guide star to be coupled with adaptive optics, thus permitting ground-based telescopes to obtain the same resolution as smaller space-based instruments but with more light-gathering power. (2) Significantly improving the limit on the mass of the electron antineutrino so that neutrinos now become a useful tool in diagnosing supernovas and we disproved the existence of a 17-keV neutrino. (3) Developing a new class of organic aerogels that have robust mechanical properties and that have significantly lower thermal conductivity than inorganic aerogels. (4) Developing a new heavy-ion accelerator concept, which may enable us to design heavy-ion experimental systems and use a heavy-ion driver for inertial fusion. (5) Designing and demonstrating a high-power, diode-pumped, solid-state laser concept that will allow us to pursue a variety of research projects, including laser material processing. (6) Demonstrating that high-performance semiconductor arrays can be fabricated more efficiently, which will make this technology available to a broad range of applications such as inertial confinement fusion for civilian power. (7) Developing a new type of fiber channel switch and new fiber channel standards for use in local- and wide-area networks, which will allow scientists and engineers to transfer data at gigabit rates. (8) Developing the nation`s only numerical model for high-technology air filtration systems. Filter designs that use this model will provide safer and cleaner environments in work areas where contamination with particulate hazardous materials is possible.

  19. Laboratory Directed Research and Development FY 1992

    International Nuclear Information System (INIS)

    Struble, G.L.; Middleton, C.; Anderson, S.E.; Baldwin, G.; Cherniak, J.C.; Corey, C.W.; Kirvel, R.D.; McElroy, L.A.

    1992-01-01

    The Laboratory Directed Research and Development (LDRD) Program at Lawrence Livermore National Laboratory (LLNL) funds projects that nurture and enrich the core competencies of the Laboratory. The scientific and technical output from the FY 1992 RD Program has been significant. Highlights include (1) Creating the first laser guide star to be coupled with adaptive optics, thus permitting ground-based telescopes to obtain the same resolution as smaller space-based instruments but with more light-gathering power. (2) Significantly improving the limit on the mass of the electron antineutrino so that neutrinos now become a useful tool in diagnosing supernovas and we disproved the existence of a 17-keV neutrino. (3) Developing a new class of organic aerogels that have robust mechanical properties and that have significantly lower thermal conductivity than inorganic aerogels. (4) Developing a new heavy-ion accelerator concept, which may enable us to design heavy-ion experimental systems and use a heavy-ion driver for inertial fusion. (5) Designing and demonstrating a high-power, diode-pumped, solid-state laser concept that will allow us to pursue a variety of research projects, including laser material processing. (6) Demonstrating that high-performance semiconductor arrays can be fabricated more efficiently, which will make this technology available to a broad range of applications such as inertial confinement fusion for civilian power. (7) Developing a new type of fiber channel switch and new fiber channel standards for use in local- and wide-area networks, which will allow scientists and engineers to transfer data at gigabit rates. (8) Developing the nation's only numerical model for high-technology air filtration systems. Filter designs that use this model will provide safer and cleaner environments in work areas where contamination with particulate hazardous materials is possible

  20. New working paradigms in research laboratories.

    Science.gov (United States)

    Keighley, Wilma; Sewing, Andreas

    2009-07-01

    Work in research laboratories, especially within centralised functions in larger organisations, is changing fast. With easier access to external providers and Contract Research Organisations, and a focus on budgets and benchmarking, scientific expertise has to be complemented with operational excellence. New concepts, globally shared projects and restricted resources highlight the constraints of traditional operating models working from Monday to Friday and nine to five. Whilst many of our scientists welcome this new challenge, organisations have to enable and foster a more business-like mindset. Organisational structures, remuneration, as well as systems in finance need to be adapted to build operations that are best-in-class rather than merely minimising negative impacts of current organisational structures.

  1. Bringing ayahuasca to the clinical research laboratory.

    Science.gov (United States)

    Riba, Jordi; Barbanoj, Manel J

    2005-06-01

    Since the winter of 1999, the authors and their research team have been conducting clinical studies involving the administration of ayahuasca to healthy volunteers. The rationale for conducting this kind of research is twofold. First, the growing interest of many individuals for traditional indigenous practices involving the ingestion of natural psychotropic drugs such as ayahuasca demands the systematic study of their pharmacological profiles in the target species, i.e., human beings. The complex nature of ayahuasca brews combining a large number of pharmacologically active compounds requires that research be carried out to establish the safety and overall pharmacological profile of these products. Second, the authors believe that the study of psychedelics in general calls for renewed attention. Although the molecular and electrophysiological level effects of these drugs are relatively well characterized, current knowledge of the mechanisms by which these compounds modify the higher order cognitive processes in the way they do is still incomplete, to say the least. The present article describes the development of the research effort carried out at the Autonomous University of Barcelona, commenting on several methodological aspects and reviewing the basic clinical findings. It also describes the research currently underway in our laboratory, and briefly comments on two new studies we plan to undertake in order to further our knowledge of the pharmacology of ayahuasca.

  2. National Storage Laboratory: a collaborative research project

    Science.gov (United States)

    Coyne, Robert A.; Hulen, Harry; Watson, Richard W.

    1993-01-01

    The grand challenges of science and industry that are driving computing and communications have created corresponding challenges in information storage and retrieval. An industry-led collaborative project has been organized to investigate technology for storage systems that will be the future repositories of national information assets. Industry participants are IBM Federal Systems Company, Ampex Recording Systems Corporation, General Atomics DISCOS Division, IBM ADSTAR, Maximum Strategy Corporation, Network Systems Corporation, and Zitel Corporation. Industry members of the collaborative project are funding their own participation. Lawrence Livermore National Laboratory through its National Energy Research Supercomputer Center (NERSC) will participate in the project as the operational site and provider of applications. The expected result is the creation of a National Storage Laboratory to serve as a prototype and demonstration facility. It is expected that this prototype will represent a significant advance in the technology for distributed storage systems capable of handling gigabyte-class files at gigabit-per-second data rates. Specifically, the collaboration expects to make significant advances in hardware, software, and systems technology in four areas of need, (1) network-attached high performance storage; (2) multiple, dynamic, distributed storage hierarchies; (3) layered access to storage system services; and (4) storage system management.

  3. Idaho national laboratory - a nuclear research center

    International Nuclear Information System (INIS)

    Zaidi Mohammed, K.

    2006-01-01

    Full text: The Idaho National Laboratory (INL) is committed to providing international nuclear leadership for the 21st Century, developing and demonstrating compelling national security technologies, and delivering excellence in science and technology as one of the United States Department of Energy's (DOE) multi program national laboratories. INL runs three major programs - Nuclear, Security and Science. Nuclear programs covers the Advanced test reactor, Six Generation IV technology concepts selected for Rand D, targeting tumors - Boron Neutron Capture therapy. Homeland Security establishes the Control System Security and Test Center, Critical Infrastructure Test Range evaluates technologies on a scalable basis, INL conducts high performance computing and visualization research and science. To provide leadership in the education and training, INL has established an Institute of Nuclear Science and Engineering (INSE) under the Center for Advanced Energy Studies (CAES) and the Idaho State University (ISU). INSE will offer a four year degree based on a newly developed curriculum - two year of basic science course work and two years of participation in project planning and development. The students enrolled in this program can continue to get a masters or a doctoral degree. This summer INSE is the host for the training of the first international group selected by the World Nuclear University (WNU) - 75 fellowship holders and their 30 instructors from 40 countries. INL has been assigned to provide future global leadership in the field of nuclear science and technology. Here, at INL, we keep safety first above all things and our logo is 'Nuclear leadership synonymous with safety leadership'. (author)

  4. US Army Research Laboratory Power-Line UAV Modeling and Simulation (ARL-PLUMS Ver 2.x) Software Tool: User Manual and Technical Report

    Science.gov (United States)

    2015-09-01

    shown have units of pF/m. This is the capacitance matrix for the 115-kV 3-phase circuit seen in Fig. 24.....................................24 Fig. 29...The window that appears when one clicks “Calculate Lambdas ”. These are the linear charge densities for the 115-kV 3-phase circuit seen in Fig. 24...calculate the capacitance matrix (Fig. 28). The diagonal entries are called the coefficients of capacitance, and the non-diagonal entries are called

  5. A wonderful laboratory and a great researcher

    Science.gov (United States)

    Sheikh, N. M.

    2004-05-01

    It was great to be associated with Prof. Dr. Karl Rawer. He devoted his life to make use of the wonderful laboratory of Nature, the Ionosphere. Through acquisition of the experimental data from AEROS satellites and embedding it with data from ground stations, it was possible to achieve a better empirical model, the International Reference Ionosphere. Prof. Dr. Karl Rawer has been as dynamic as the Ionosphere. His vision about the ionospheric data is exceptional and has helped the scientific and engineering community to make use of his vision in advancing the dimensions of empirical modelling. As a human being, Prof. Dr. Karl Rawer has all the traits of an angel from Heaven. In short he developed a large team of researchers forming a blooming tree from the parent node. Ionosphere still plays an important role in over the horizon HF Radar and GPs satellite data reduction.

  6. A Revised Interface for the ARL Topodef Mobility Design Tool

    Science.gov (United States)

    2012-04-01

    designed paths as though moving down a conveyor belt . Giving paths an existence independent of the nodes that travel along them not only makes their...A Revised Interface for the ARL Topodef Mobility Design Tool by Andrew J. Toth and Michael Christensen ARL-TR-5980 April 2012...Disclaimers The findings in this report are not to be construed as an official Department of the Army position unless so designated by other

  7. Tritium Research Laboratory safety analysis report

    Energy Technology Data Exchange (ETDEWEB)

    Wright, D.A.

    1979-03-01

    Design and operational philosophy has been evolved to keep radiation exposures to personnel and radiation releases to the environment as low as reasonably achievable. Each experiment will be doubly contained in a glove box and will be limited to 10 grams of tritium gas. Specially designed solid-hydride storage beds may be used to store temporarily up to 25 grams of tritium in the form of tritides. To evaluate possible risks to the public or the environment, a review of the Sandia Laboratories Livermore (SLL) site was carried out. Considered were location, population, land use, meteorology, hydrology, geology, and seismology. The risks and the extent of damage to the TRL and vital systems were evaluated for flooding, lightning, severe winds, earthquakes, explosions, and fires. All of the natural phenomena and human error accidents were considered credible, although the extent of potential damage varied. However, rather than address the myriad of specific individual consequences of each accident scenario, a worst-case tritium release caused indirectly by an unspecified natural phenomenon or human error was evaluated. The maximum credible radiological accident is postulated to result from the release of the maximum quantity of gas from one experiment. Thus 10 grams of tritium gas was used in the analysis to conservatively estimate the maximum whole-body dose of 1 rem at the site boundary and a maximum population dose of 600 man-rem. Accidental release of this amount of tritium implies simultaneous failure of two doubly contained systems, an occurrence considered not credible. Nuclear criticality is impossible in this facility. Based upon the analyses performed for this report, we conclude that the Tritium Research Laboratory can be operated without undue risk to employees, the general public, or the environment. (ERB)

  8. Tritium Research Laboratory safety analysis report

    International Nuclear Information System (INIS)

    Wright, D.A.

    1979-03-01

    Design and operational philosophy has been evolved to keep radiation exposures to personnel and radiation releases to the environment as low as reasonably achievable. Each experiment will be doubly contained in a glove box and will be limited to 10 grams of tritium gas. Specially designed solid-hydride storage beds may be used to store temporarily up to 25 grams of tritium in the form of tritides. To evaluate possible risks to the public or the environment, a review of the Sandia Laboratories Livermore (SLL) site was carried out. Considered were location, population, land use, meteorology, hydrology, geology, and seismology. The risks and the extent of damage to the TRL and vital systems were evaluated for flooding, lightning, severe winds, earthquakes, explosions, and fires. All of the natural phenomena and human error accidents were considered credible, although the extent of potential damage varied. However, rather than address the myriad of specific individual consequences of each accident scenario, a worst-case tritium release caused indirectly by an unspecified natural phenomenon or human error was evaluated. The maximum credible radiological accident is postulated to result from the release of the maximum quantity of gas from one experiment. Thus 10 grams of tritium gas was used in the analysis to conservatively estimate the maximum whole-body dose of 1 rem at the site boundary and a maximum population dose of 600 man-rem. Accidental release of this amount of tritium implies simultaneous failure of two doubly contained systems, an occurrence considered not credible. Nuclear criticality is impossible in this facility. Based upon the analyses performed for this report, we conclude that the Tritium Research Laboratory can be operated without undue risk to employees, the general public, or the environment

  9. Research Laboratory of Mixed Radiation Dosimetry

    International Nuclear Information System (INIS)

    2002-01-01

    Full text: Two main topics of the research work in the Laboratory of Mixed Radiation Dosimetry in 2001 were: development of recombination methods for dosimetry of mixed radiation fields and maintenance and development of unique in Poland reference neutron fields. Additionally research project on internal dosimetry were carried out in collaboration with Division of Radiation Protection Service. RECOMBINATION METHODS Recombination methods make use of the fact that the initial recombination of ions in the gas cavity of the ionization chamber depends on local ionization density. The later can be related to linear energy transfer (LET) and provides information on radiation quality of the investigated radiation fields. Another key feature of the initial recombination is that it does not depend of dose rate. Conditions of initial (local) recombination can be achieved in specially designed high pressure tissue-equivalent ionization chambers, called the recombination chambers. They are usually parallel-plate ionization chambers filled with a tissue-equivalent gas mixture under a pressure of order 1 MPa. The spacing between electrodes is of order of millimeters. At larger spacing, the volume recombination limits the maximum dose rate at which the chamber can be properly operated. The output of the chamber is the ionization current (or collected charge) as a function of collecting voltage. All the recombination methods require the measurement of the ionization current (or charge) at least at two values of the collecting voltage applied to the chamber. The highest voltage should provide the conditions close to saturation (but below discharge or multiplication). The ionization current measured at maximum applied voltage is proportional to the absorbed dose, D, (some small corrections for lack of saturation can be introduced when needed). Measurements at other voltages are needed for the determination of radiation quality. The total dose equivalent in a mixed radiation field is

  10. Research programs at the Department of Energy National Laboratories. Volume 2: Laboratory matrix

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-01

    For nearly fifty years, the US national laboratories, under the direction of the Department of Energy, have maintained a tradition of outstanding scientific research and innovative technological development. With the end of the Cold War, their roles have undergone profound changes. Although many of their original priorities remain--stewardship of the nation`s nuclear stockpile, for example--pressing budget constraints and new federal mandates have altered their focus. Promotion of energy efficiency, environmental restoration, human health, and technology partnerships with the goal of enhancing US economic and technological competitiveness are key new priorities. The multiprogram national laboratories offer unparalleled expertise in meeting the challenge of changing priorities. This volume aims to demonstrate each laboratory`s uniqueness in applying this expertise. It describes the laboratories` activities in eleven broad areas of research that most or all share in common. Each section of this volume is devoted to a single laboratory. Those included are: Argonne National Laboratory; Brookhaven National Laboratory; Idaho National Engineering Laboratory; Lawrence Berkeley Laboratory; Lawrence Livermore National Laboratory; Los Alamos National Laboratory; National Renewable Energy Laboratory; Oak Ridge National Laboratory; Pacific Northwest Laboratory; and Sandia National Laboratories. The information in this volume was provided by the multiprogram national laboratories and compiled at Lawrence Berkeley Laboratory.

  11. Research and Progress on Virtual Cloud Laboratory

    OpenAIRE

    Zhang Jian Wei; Shang Zhi Hui; Yuan Chen; Ma Lin Lin; Cai Zeng Yu; Hu Chun Hui

    2016-01-01

    In recent years, cloud computing technology has experienced continuous development and improvement, and has gradually expanded to the education sector. First, this paper will introduce the background knowledge of the current virtual cloud laboratory; by comparing the advantages and disadvantages between traditional laboratory and virtual cloud laboratory, and comparing the application, advantages and disadvantages, and development trend of OpenStack technology and VMWare technology in safety,...

  12. Welded rupture disc assemblies for use in Tritium Research Laboratory

    International Nuclear Information System (INIS)

    Faltings, R.E.

    1976-01-01

    Welded rupture disc assemblies were investigated and developed in various ranges for probable use by experimenters in their activities in the Tritium Research Laboratory at Sandia Laboratories, Livermore. This study indicates that currently welded rupture disc assemblies with appropriate testing and installation by certified pressure installers may be used in pressure systems in the Tritium Research Laboratory and other areas at SLL

  13. Research at the Oak Ridge National Laboratory (ORNL)

    International Nuclear Information System (INIS)

    Postma, H.

    1980-01-01

    The Oak Ridge National Laboratory is a large (5300 people), US-government-funded laboratory, which performs research in many disciplines and in many technological areas. Programs and organization of ORNL are described for the People's Republic of China

  14. 78 FR 28292 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2013-05-14

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board; Notice of Meetings; Amendment The... Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development...

  15. GTP-binding-defective ARL4D alters mitochondrial morphology and membrane potential.

    Directory of Open Access Journals (Sweden)

    Chun-Chun Li

    Full Text Available ARL4D, ARL4A, and ARL4C are closely related members of the ADP-ribosylation factor/ARF-like protein (ARF/ARL family of GTPases. All three ARL4 proteins contain nuclear localization signals (NLSs at their C-termini and are primarily found at the plasma membrane, but they are also present in the nucleus and cytoplasm. ARF function and localization depends on their controlled binding and hydrolysis of GTP. Here we show that GTP-binding-defective ARL4D is targeted to the mitochondria, where it affects mitochondrial morphology and function. We found that a portion of endogenous ARL4D and the GTP-binding-defective ARL4D mutant ARL4D(T35N reside in the mitochondria. The N-terminal myristoylation of ARL4D(T35N was required for its localization to mitochondria. The localization of ARL4D(T35N to the mitochondria reduced the mitochondrial membrane potential (ΔΨm and caused mitochondrial fragmentation. Furthermore, the C-terminal NLS region of ARL4D(T35N was required for its effect on the mitochondria. This study is the first to demonstrate that the dysfunctional GTP-binding-defective ARL4D is targeted to mitochondria, where it subsequently alters mitochondrial morphology and membrane potential.

  16. The Swedish Research Councils' Laboratory progress report for 1975

    International Nuclear Information System (INIS)

    Rudstam, G.

    1976-01-01

    The Swedish Research Councils' Laboratory herewith presents its progress report for 1975. The report summarizes the current projects carried out by the research groups working at the laboratory. The very efficient assistance of the staff of the laboratory is greatfully acknowledged. The laboratory has been financially supported by the Atomic Research Council, the Medical Research Council, the Natural Science Research Council, and the Board of Technical Development. Valuable support in various ways has also been given by the Atomic Energy Company (AB Atomenergi). (author)

  17. Research report 1987-1989: Environmental Quality Laboratory and Environmental Engineering Science, W. M. Keck Laboratories

    OpenAIRE

    Brooks, Norman H.

    1990-01-01

    This research biennial report for 1987-89 covers the activities of both the Environmental Engineering Science program and the Environmental Quality Laboratory for the period October 1987-November 1989. Environmental Engineering Science is the degree-granting academic program housed in the Keck Laboratories, with associated research projects. The Environmental Quality Laboratory is a research center focusing on large scale problems of environmental quality and natural resources. All the facult...

  18. Mobile teleoperator research at Savannah River Laboratory

    International Nuclear Information System (INIS)

    Byrd, J.S.

    1985-01-01

    A Robotics Technology Group was organized at Savannah River Laboratory to employ modern automation and robotics for applications at the Savannah River site. Several industrial robots have been installed in plant processes. Other robotics systems are under development in the laboratories, including mobile teleoperators for general remote tasks and emergency response operations. This paper discusses present work on a low-cost wheeled mobile vehicle, a modular light duty manipulator arm, a large gantry telerobot system, and a high technology six-legged walking robot with a teleoperated arm

  19. Ultra-Short-Pulse Laser Effects Research and Analysis Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Enables research into advanced laser countermeasure techniques.DESCRIPTION: This laser facility has a capability to produce very high peak power levels of...

  20. Solar Radiation Research Laboratory | Energy Systems Integration Facility |

    Science.gov (United States)

    Solar Radiation Research Laboratory (SRRL) has been collecting continuous measurements of basic solar continuous operation. More than 75 instruments contribute to the Baseline Measurement System by recording

  1. Sandia, California Tritium Research Laboratory transition and reutilization project

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, T.B. [Sandia National Lab., Albuquerque, NM (United States)

    1997-02-01

    This paper describes a project within Sandia National Laboratory to convert the shut down Tritium Research Laboratory into a facility which could be reused within the laboratory complex. In the process of decommissioning and decontaminating the facility, the laboratory was able to save substantial financial resources by transferring much existing equipment to other DOE facilities, and then expeditiously implementing a decontamination program which has resulted in the building being converted into laboratory space for new lab programs. This project of facility reuse has been a significant financial benefit to the laboratory.

  2. Laboratory Directed Research and Development FY-15 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Pillai, Rekha Sukamar [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-03-01

    The Laboratory Directed Research and Development (LDRD) Program at Idaho National Laboratory (INL) reports its status to the U.S. Department of Energy (DOE) by March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the laboratory director broad flexibility for program implementation. LDRD funds are obtained through a charge to all INL programs. This report includes summaries of all INL LDRD research activities supported during Fiscal Year (FY) 2015.

  3. Laboratory Directed Research and Development FY-10 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Dena Tomchak

    2011-03-01

    The FY 2010 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support the future DOE missions and national research priorities. LDRD is essential to the INL -- it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enhances technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development.

  4. Material Transfer Agreement (MTA) | Frederick National Laboratory for Cancer Research

    Science.gov (United States)

    Material Transfer Agreements are appropriate for exchange of materials into or out of the Frederick National Laboratory for research or testing purposes, with no collaborative research by parties involving the materials.

  5. Senior Laboratory Animal Technician | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused

  6. Laboratory Directed Research and Development annual report, fiscal year 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The Department of Energy Order 413.2(a) establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 413.2, LDRD is research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this Order. DOE Order 413.2 requires that each laboratory submit an annual report on its LDRD activities to the cognizant Secretarial Officer through the appropriate Operations Office Manager. The report provided in this document represents Pacific Northwest National Laboratory`s LDRD report for FY 1997.

  7. Laboratory Technology Research: Abstracts of FY 1996 projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of this country: the world-class basic research capability of the DOE Energy Research (ER) multi-program national laboratories and the unparalleled entrepreneurial spirit of American industry. Projects supported by the LTR program are conducted by the five ER multi-program laboratories: Argonne, Brookhaven, Lawrence Berkeley, Oak Ridge, and Pacific Northwest National Laboratories. These projects explore the applications of basic research advances relevant to Department of Energy`s (DOE) mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials, intelligent processing/manufacturing research, and sustainable environments.

  8. Copyright Policy and Practice in Electronic Reserves among ARL Libraries

    Science.gov (United States)

    Hansen, David R.; Cross, William M.; Edwards, Phillip M.

    2013-01-01

    This paper presents the results of a survey of 110 ARL institutions regarding their copyright policies for providing electronic reserves. It compiles descriptive statistics on library practice as well as coding responses to reveal trends and shared practices. Finally, it presents conclusions about policy making, decision making and risk aversion…

  9. Structure, Features, and Faculty Content in ARL Member Repositories

    Science.gov (United States)

    Mercer, Holly; Koenig, Jay; McGeachin, Robert B.; Tucker, Sandra L.

    2011-01-01

    Questions about the optimal way to present repository content to authors, submitters, and end-users, prompted this study. The authors examined, through an observation and a survey, the institutional repositories of peer institutions in the ARL for good practices related to the presentation and organization of faculty-authored institutional…

  10. The U.S. Army Research Laboratory’s Auditory Research for the Dismounted Soldier: Present (2009-2011) and Future

    Science.gov (United States)

    2012-03-01

    auditory experts and testers of prototype headsets. The multidisciplinary and multifaceted nature of ART research has been reflected in articles ...Acoustics, International Journal of Audiology , Ear and Hearing, Archives of Acoustics, Military Psychology, Journal of the Acoustical Society of America... Audiological Society, American Academy of Audiology (AudiologyNOW), and Joint Defense/Veterans Audiology Conference. A list of 2009–2011 ARL-HRED

  11. Safeguards research at Lawrence Livermore Laboratory

    International Nuclear Information System (INIS)

    Dunn, D.R.; Huebel, J.G.; Poggio, A.J.

    1980-01-01

    The LLL safeguards research program includes inspection methods, facility assessment methodologies, value-impact analysis, vulnerability analysis of accounting systems, compliance with regulations, process monitoring, etc. Each of those projects is described as are their goals and progress

  12. Laboratory Directed Research and Development Program: FY 2015 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    SLAC,

    2016-04-04

    The Department of Energy (DOE) and the SLAC National Accelerator Laboratory (SLAC) encourage innovation, creativity, originality and quality to maintain the Laboratory’s research activities and staff at the forefront of science and technology. To further advance its scientific research capabilities, the Laboratory allocates a portion of its funds for the Laboratory Directed Research and Development (LDRD) program. With DOE guidance, the LDRD program enables SLAC scientists to make rapid and significant contributions that seed new strategies for solving important national science and technology problems. The LDRD program is conducted using existing research facilities.

  13. Laboratory Directed Research and Development Annual Report FY 2017

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, Kelly O.

    2018-03-30

    A national laboratory must establish and maintain an environment in which creativity and innovation are encouraged and supported in order to fulfill its missions and remain viable in the long term. As such, multiprogram laboratories are given discretion to allocate a percentage of their operating budgets to support research and development projects that align to PNNL’s and DOE’s missions and support the missions of other federal agencies, including DHS, DOD, and others. DOE Order 413.2C sets forth DOE’s Laboratory Directed Research and Development (LDRD) policy and guidelines for DOE multiprogram laboratories, and it authorizes the national laboratories to allocate up to 6 percent of their operating budgets to fund the program. LDRD is innovative research and development, selected by the Laboratory Director or his/her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory. The projects supported by LDRD funding all have demonstrable ties to DOE/DHS missions and may also be relevant to the missions of other federal agencies that sponsor work at the Laboratory. The program plays a key role in attracting the best and brightest scientific staff, which is needed to serve the highest priority DOE mission objectives. Individual project reports comprise the bulk of this LDRD report. The Laboratory focuses its LDRD research on scientific assets that often address more than one scientific discipline.

  14. Laboratory Directed Research and Development Annual Report FY 2016

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, Kelly O. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2017-03-30

    A national laboratory must establish and maintain an environment in which creativity and innovation are encouraged and supported in order to fulfill its missions and remain viable in the long term. As such, multiprogram laboratories are given discretion to allocate a percentage of their operating budgets to support research and development projects that align to PNNL’s and DOE’s missions and support the missions of other federal agencies, including DHS, DOD, and others. DOE Order 413.2C sets forth DOE’s Laboratory Directed Research and Development (LDRD) policy and guidelines for DOE multiprogram laboratories, and it authorizes the national laboratories to allocate up to 6 percent of their operating budgets to fund the program. LDRD is innovative research and development, selected by the Laboratory Director or his/her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory. The projects supported by LDRD funding all have demonstrable ties to DOE/DHS missions and may also be relevant to the missions of other federal agencies that sponsor work at the Laboratory. The program plays a key role in attracting the best and brightest scientific staff, which is needed to serve the highest priority DOE mission objectives. Individual project reports comprise the bulk of this LDRD report. The Laboratory focuses its LDRD research on scientific assets that often address more than one scientific discipline.

  15. Research Review: Laboratory Student Magazine Programs.

    Science.gov (United States)

    Wheeler, Tom

    1994-01-01

    Explores research on student-produced magazines at journalism schools, including the nature of various programs and curricular structures, ethical considerations, and the role of faculty advisors. Addresses collateral sources that provide practical and philosophical foundations for the establishment and conduct of magazine production programs.…

  16. Naval Research Laboratory Fact Book 2012

    Science.gov (United States)

    2012-11-01

    markets NRL’s patented inventions, negotiates patent license agreements under which the Navy grants a licensee the right to make, use, and sell NRL...Sr. Licensing Associate Social Media Marketing Associate Licensing Associate Management Analyst Administrative Assistant (SCEP) Administrative...ADMINISTRATIVE OFFICE SENIOR SCIENTIST FOR SUN-EARTH SYSTEMS RESEARCH 7605 GEOSPACE SCIENCE AND TECHNOLOGY BRANCH 7630 SPACE TEST PROGRAM ( STP

  17. Where Does My Augmented Reality Learning Experience (ARLE) Belong? A Student and Teacher Perspective to Positioning ARLEs

    Science.gov (United States)

    Drljevic, Neven; Wong, Lung Hsiang; Boticki, Ivica

    2017-01-01

    The paper provides a high-level review of the current state of techno-pedagogical design in Augmented Reality Learning Experiences (ARLEs). The review is based on a rubric constructed from the Meaningful Learning with ICT framework and the Orchestration Load reduction framework, providing, respectively, a view of primarily student- and primarily…

  18. Network Science Research Laboratory (NSRL) Telemetry Warehouse

    Science.gov (United States)

    2016-06-01

    Development of an architectural framework to validate performance of a distributed trust management protocol, called trustd, required a high...all of the most popular programming languages currently in use, including Java , Python, and C#. Work is underway to provide Python bindings to the...client library. NSRL researchers plan to develop Python and Java wrappers for this library. Sensors must obtain an experiment session token in

  19. Air Force Research Laboratory Technology Milestones 2007

    Science.gov (United States)

    2007-01-01

    alertness. For more information contact7 publicaffairs@afosraf.mil , (703)696-7797 ....... F d ed Researc ers Develop New Software Model to Improve Aircraft...and replacing conventional tail control surfaces with more innovative control U effectors. m For more information contact 22 afri. rb. marketing ...City, New Jersey). U For more information contact 23 ofr1.rb, marketing @wpafb.afmi1 (937)255-2074 AFRL Researchers Perform Functionally - Graded Material

  20. Argonne National Laboratory Research Highlights 1988

    International Nuclear Information System (INIS)

    Anon.

    1988-01-01

    The research and development highlights are summarized. The world's brightest source of X-rays could revolutionize materials research. Test of a prototype insertion device, a key in achieving brilliant X-ray beams, have given the first glimpse of the machine's power. Superconductivity research focuses on the new materials' structure, economics and applications. Other physical science programs advance knowledge of material structures and properties, nuclear physics, molecular structure, and the chemistry and structure of coal. New programming approaches make advanced computers more useful. Innovative approaches to fighting cancer are being developed. More experiments confirm the passive safety of Argonne's Integral Fast Reactor concept. Device simplifies nuclear-waste processing. Advanced fuel cell could provide better mileage, more power than internal combustion engine. New instruments find leaks in underground pipe, measure sodium impurities in molten liquids, detect flaws in ceramics. New antibody findings may explain ability to fight many diseases. Cadmium in cigarettes linked to bone loss in women. Programs fight deforestation in Nepal. New technology could reduce acid rain, mitigate greenhouse effect, enhance oil recovery. Innovative approaches transfer Argonne-developed technology to private industry. Each year Argonne educational programs reach some 1200 students

  1. Laboratory Directed Research and Development Program FY 2006 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Sjoreen, Terrence P [ORNL

    2007-04-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the US Departmental of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2006. The associated FY 2006 ORNL LDRD Self-Assessment (ORNL/PPA-2007/2) provides financial data about the FY 2006 projects and an internal evaluation of the program's management process.

  2. Adverse reproduction outcomes among employees working in biomedical research laboratories

    DEFF Research Database (Denmark)

    Wennborg, H.; Bonde, Jens Peter; Stenbeck, M.

    2002-01-01

    Objectives The aim of the study was to investigate reproductive outcomes such as birthweight, preterm births, and postterm births among women working in research laboratories while pregnant. Methods Female university personnel were identified from a source cohort of Swedish laboratory employees...

  3. Laboratory Directed Research and Development Program Assessment for FY 2014

    Energy Technology Data Exchange (ETDEWEB)

    Hatton, D. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2014-03-01

    Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2B dated April 19, 2006. This report fulfills that requirement.

  4. Laboratory directed research and development program, FY 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-01

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory`s forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances the Laboratory`s core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. Areas eligible for support include: (1) Work in forefront areas of science and technology that enrich Laboratory research and development capability; (2) Advanced study of new hypotheses, new experiments, and innovative approaches to develop new concepts or knowledge; (3) Experiments directed toward proof of principle for initial hypothesis testing or verification; and (4) Conception and preliminary technical analysis to explore possible instrumentation, experimental facilities, or new devices.

  5. Radiotracer laboratory for agricultural research at the Malaysian Nuclear Agency

    International Nuclear Information System (INIS)

    Nashriyah Mat; Misman Sumin; Maizatul Akmam Mhd Nasir

    2007-01-01

    Radiotracer Laboratory for agricultural research at the Malaysian Nuclear Agency was established since 1990. It accommodates three laboratories, three chemical temporary storage compartments plus one compartment for storage of pressurized gas. This facility is situated in ground floor of Block 44, Agrotechnology and Biosciences Division, Dengkil Complex. Currently it houses a liquid scintillation counter, sample oxidizer, gas liquid chromatography, high performance liquid chromatography and auxiliary equipments. A road map for this laboratory will be discussed in relation with present scenario i.e. R and D service, training and consultancy provided by this laboratory; and future requirements and direction. (Author)

  6. Summary and Findings of the ARL Dynamic Failure Forum

    Science.gov (United States)

    2016-09-29

    institutions not being the principal investigator (PI) on a project or the lead author of a paper comes at the price of being seen as playing a...Development and Engineering Center Lee Magness US Army Research Laboratory Jim McCauley US Army Research Laboratory Jason McDonald US Army Research

  7. Argonne National Laboratory research offers clues to Alzheimer's plaques

    CERN Multimedia

    2003-01-01

    Researchers from Argonne National Laboratory and the University of Chicago have developed methods to directly observe the structure and growth of microscopic filaments that form the characteristic plaques found in the brains of those with Alzheimer's Disease (1 page).

  8. Laboratory directed research and development 2006 annual report.

    Energy Technology Data Exchange (ETDEWEB)

    Westrich, Henry Roger

    2007-03-01

    This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 2006. In addition to a programmatic and financial overview, the report includes progress reports from 430 individual R&D projects in 17 categories.

  9. Global Impact | Frederick National Laboratory for Cancer Research

    Science.gov (United States)

    Through its direct support of clinical research, Frederick National Laboratory activities are not limited to national programs. The labis actively involved in more than 400 domestic and international studies related to cancer; influenza, HIV, E

  10. Earth System Research Laboratory Long-Term Surface Aerosol Measurements

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Aerosol measurements began at the NOAA Earth System Research Laboratory (ESRL) Global Monitoring Division (GMD) baseline observatories in the mid-1970's with the...

  11. Technical Service Agreement (TSA) | Frederick National Laboratory for Cancer Research

    Science.gov (United States)

    Frederick National Laboratory for Cancer Research (FNLCR) scientists provide services and solutions to collaborators through the Technical Services Program, whose portfolio includes more than 200 collaborations with more than 80 partners. The Frederi

  12. Laboratory Directed Research and Development Program

    International Nuclear Information System (INIS)

    Ogeka, G.J.; Romano, A.J.

    1992-12-01

    This report briefly discusses the following research: Advances in Geoexploration; Transvenous Coronary Angiography with Synchrotron X-Rays; Borehole Measurements of Global Warming; Molecular Ecology: Development of Field Methods for Microbial Growth Rate and Activity Measurements; A New Malaria Enzyme - A Potential Source for a New Diagnostic Test for Malaria and a Target for a New Antimalarial Drug; Basic Studies on Thoron and Thoron Precursors; Cloning of the cDNA for a Human Serine/Threonine Protein Kinase that is Activated Specifically by Double-Stranded DNA; Development of an Ultra-Fast Laser System for Accelerator Applications; Cluster Impact Fusion; Effect of a Bacterial Spore Protein on Mutagenesis; Structure and Function of Adenovirus Penton Base Protein; High Resolution Fast X-Ray Detector; Coherent Synchrotron Radiation Longitudinal Bunch Shape Monitor; High Grain Harmonic Generation Experiment; BNL Maglev Studies; Structural Investigations of Pt-Based Catalysts; Studies on the Cellular Toxicity of Cocaine and Cocaethylene; Human Melanocyte Transformation; Exploratory Applications of X-Ray Microscopy; Determination of the Higher Ordered Structure of Eukaryotic Chromosomes; Uranium Neutron Capture Therapy; Tunneling Microscopy Studies of Nanoscale Structures; Nuclear Techiques for Study of Biological Channels; RF Sources for Accelerator Physics; Induction and Repair of Double-Strand Breaks in the DNA of Human Lymphocytes; and An EBIS Source of High Charge State Ions up to Uranium

  13. Laboratory Directed Research and Development Program

    Energy Technology Data Exchange (ETDEWEB)

    Ogeka, G.J.; Romano, A.J.

    1992-12-01

    This report briefly discusses the following research: Advances in Geoexploration; Transvenous Coronary Angiography with Synchrotron X-Rays; Borehole Measurements of Global Warming; Molecular Ecology: Development of Field Methods for Microbial Growth Rate and Activity Measurements; A New Malaria Enzyme - A Potential Source for a New Diagnostic Test for Malaria and a Target for a New Antimalarial Drug; Basic Studies on Thoron and Thoron Precursors; Cloning of the cDNA for a Human Serine/Threonine Protein Kinase that is Activated Specifically by Double-Stranded DNA; Development of an Ultra-Fast Laser System for Accelerator Applications; Cluster Impact Fusion; Effect of a Bacterial Spore Protein on Mutagenesis; Structure and Function of Adenovirus Penton Base Protein; High Resolution Fast X-Ray Detector; Coherent Synchrotron Radiation Longitudinal Bunch Shape Monitor; High Grain Harmonic Generation Experiment; BNL Maglev Studies; Structural Investigations of Pt-Based Catalysts; Studies on the Cellular Toxicity of Cocaine and Cocaethylene; Human Melanocyte Transformation; Exploratory Applications of X-Ray Microscopy; Determination of the Higher Ordered Structure of Eukaryotic Chromosomes; Uranium Neutron Capture Therapy; Tunneling Microscopy Studies of Nanoscale Structures; Nuclear Techiques for Study of Biological Channels; RF Sources for Accelerator Physics; Induction and Repair of Double-Strand Breaks in the DNA of Human Lymphocytes; and An EBIS Source of High Charge State Ions up to Uranium.

  14. Space Station life science research facility - The vivarium/laboratory

    Science.gov (United States)

    Hilchey, J. D.; Arno, R. D.

    1985-01-01

    Research opportunities possible with the Space Station are discussed. The objective of the research program will be study gravity relationships for animal and plant species. The equipment necessary for space experiments including vivarium facilities are described. The cost of the development of research facilities such as the vivarium/laboratory and a bioresearch centrifuge is examined.

  15. Biological and Physical Space Research Laboratory 2002 Science Review

    Science.gov (United States)

    Curreri, P. A. (Editor); Robinson, M. B. (Editor); Murphy, K. L. (Editor)

    2003-01-01

    With the International Space Station Program approaching core complete, our NASA Headquarters sponsor, the new Code U Enterprise, Biological and Physical Research, is shifting its research emphasis from purely fundamental microgravity and biological sciences to strategic research aimed at enabling human missions beyond Earth orbit. Although we anticipate supporting microgravity research on the ISS for some time to come, our laboratory has been vigorously engaged in developing these new strategic research areas.This Technical Memorandum documents the internal science research at our laboratory as presented in a review to Dr. Ann Whitaker, MSFC Science Director, in July 2002. These presentations have been revised and updated as appropriate for this report. It provides a snapshot of the internal science capability of our laboratory as an aid to other NASA organizations and the external scientific community.

  16. 1995 Laboratory-Directed Research and Development Annual report

    Energy Technology Data Exchange (ETDEWEB)

    Cauffman, D.P.; Shoaf, D.L.; Hill, D.A.; Denison, A.B.

    1995-12-31

    The Laboratory-Directed Research and Development Program (LDRD) is a key component of the discretionary research conducted by Lockheed Idaho Technologies Company (Lockheed Idaho) at the Idaho National Engineering Laboratory (INEL). The threefold purpose and goal of the LDRD program is to maintain the scientific and technical vitality of the INEL, respond to and support new technical opportunities, and enhance the agility and flexibility of the national laboratory and Lockheed Idaho to address the current and future missions of the Department of Energy.

  17. 1995 Laboratory-Directed Research and Development Annual report

    International Nuclear Information System (INIS)

    Cauffman, D.P.; Shoaf, D.L.; Hill, D.A.; Denison, A.B.

    1995-01-01

    The Laboratory-Directed Research and Development Program (LDRD) is a key component of the discretionary research conducted by Lockheed Idaho Technologies Company (Lockheed Idaho) at the Idaho National Engineering Laboratory (INEL). The threefold purpose and goal of the LDRD program is to maintain the scientific and technical vitality of the INEL, respond to and support new technical opportunities, and enhance the agility and flexibility of the national laboratory and Lockheed Idaho to address the current and future missions of the Department of Energy

  18. Design study of underground facility of the Underground Research Laboratory

    International Nuclear Information System (INIS)

    Hibiya, Keisuke; Akiyoshi, Kenji; Ishizuka, Mineo; Anezaki, Susumu

    1998-03-01

    Geoscientific research program to study deep geological environment has been performed by Power Reactor and Nuclear Fuel Development Corporation (PNC). This research is supported by 'Long-Term Program for Research, Development and Utilization of Nuclear Energy'. An Underground Research Laboratory is planned to be constructed at Shoma-sama Hora in the research area belonging to PNC. A wide range of geoscientific research and development activities which have been previously studied at the Tono Area is planned in the laboratory. The Underground Research Laboratory is consisted of Surface Laboratory and Underground Research Facility located from the surface down to depth between several hundreds and 1,000 meters. Based on the results of design study in last year, the design study performed in this year is to investigate the followings in advance of studies for basic design and practical design: concept, design procedure, design flow and total layout. As a study for the concept of the underground facility, items required for the facility are investigated and factors to design the primary form of the underground facility are extracted. Continuously, design methods for the vault and the underground facility are summarized. Furthermore, design procedures of the extracted factors are summarized and total layout is studied considering the results to be obtained from the laboratory. (author)

  19. Laboratory Directed Research and Development Program Assessment for FY 2008

    Energy Technology Data Exchange (ETDEWEB)

    Looney, J P; Fox, K J

    2008-03-31

    Brookhaven National Laboratory (BNL) is a multidisciplinary Laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal Year 2008 spending was $531.6 million. There are approximately 2,800 employees, and another 4,300 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development,' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. To be a premier scientific Laboratory, BNL must continuously foster groundbreaking scientific research and renew its research agenda. The competition for LDRD funds stimulates Laboratory scientists to think in new and creative ways, which becomes a major factor in achieving and maintaining research excellence and a means to address National needs within the overall mission of the DOE and BNL. By fostering high-risk, exploratory research, the LDRD program helps

  20. The Johns Hopkins Hunterian Laboratory Philosophy: Mentoring Students in a Scientific Neurosurgical Research Laboratory.

    Science.gov (United States)

    Tyler, Betty M; Liu, Ann; Sankey, Eric W; Mangraviti, Antonella; Barone, Michael A; Brem, Henry

    2016-06-01

    After over 50 years of scientific contribution under the leadership of Harvey Cushing and later Walter Dandy, the Johns Hopkins Hunterian Laboratory entered a period of dormancy between the 1960s and early 1980s. In 1984, Henry Brem reinstituted the Hunterian Neurosurgical Laboratory, with a new focus on localized delivery of therapies for brain tumors, leading to several discoveries such as new antiangiogenic agents and Gliadel chemotherapy wafers for the treatment of malignant gliomas. Since that time, it has been the training ground for 310 trainees who have dedicated their time to scientific exploration in the lab, resulting in numerous discoveries in the area of neurosurgical research. The Hunterian Neurosurgical Laboratory has been a unique example of successful mentoring in a translational research environment. The laboratory's philosophy emphasizes mentorship, independence, self-directed learning, creativity, and people-centered collaboration, while maintaining productivity with a focus on improving clinical outcomes. This focus has been served by the diverse backgrounds of its trainees, both in regard to educational status as well as culturally. Through this philosophy and strong legacy of scientific contribution, the Hunterian Laboratory has maintained a positive and productive research environment that supports highly motivated students and trainees. In this article, the authors discuss the laboratory's training philosophy, linked to the principles of adult learning (andragogy), as well as the successes and the limitations of including a wide educational range of students in a neurosurgical translational laboratory and the phenomenon of combining clinical expertise with rigorous scientific training.

  1. Laboratory directed research and development annual report: Fiscal year 1992

    International Nuclear Information System (INIS)

    1993-01-01

    The Department of Energy Order DOE 5000.4A establishes DOE's policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 5000.4A, LDRD is ''research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this order. Consistent with the Mission Statement and Strategic Plan provided in PNL's Institutional Plan, the LDRD investments are focused on developing new and innovative approaches to research related to our ''core competencies.'' Currently, PNL's core competencies have been identified as: integrated environmental research; process science and engineering; energy distribution and utilization. In this report, the individual summaries of Laboratory-level LDRD projects are organized according to these corecompetencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. The projects described in this report represent PNL's investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. The report provides an overview of PNL's LDRD program and the management process used for the program and project summaries for each LDRD project

  2. Laboratory directed research and development annual report: Fiscal year 1992

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    The Department of Energy Order DOE 5000.4A establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 5000.4A, LDRD is ``research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this order. Consistent with the Mission Statement and Strategic Plan provided in PNL`s Institutional Plan, the LDRD investments are focused on developing new and innovative approaches to research related to our ``core competencies.`` Currently, PNL`s core competencies have been identified as: integrated environmental research; process science and engineering; energy distribution and utilization. In this report, the individual summaries of Laboratory-level LDRD projects are organized according to these corecompetencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. The projects described in this report represent PNL`s investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. The report provides an overview of PNL`s LDRD program and the management process used for the program and project summaries for each LDRD project.

  3. Laboratory directed research and development annual report: Fiscal year 1992

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    The Department of Energy Order DOE 5000.4A establishes DOE's policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 5000.4A, LDRD is research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this order. Consistent with the Mission Statement and Strategic Plan provided in PNL's Institutional Plan, the LDRD investments are focused on developing new and innovative approaches to research related to our core competencies.'' Currently, PNL's core competencies have been identified as: integrated environmental research; process science and engineering; energy distribution and utilization. In this report, the individual summaries of Laboratory-level LDRD projects are organized according to these corecompetencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. The projects described in this report represent PNL's investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. The report provides an overview of PNL's LDRD program and the management process used for the program and project summaries for each LDRD project.

  4. 76 FR 19188 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2011-04-06

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical... the panels of the Joint Biomedical Laboratory Research and Development and Clinical Science Research.... Neurobiology-D June 10, 2011 Crowne Plaza DC/Silver Spring. Clinical Research Program June 13, 2011 VA Central...

  5. 78 FR 66992 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2013-11-07

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical... the panels of the Joint Biomedical Laboratory Research and Development and Clinical Science Research..., behavioral, and clinical science research. The panel meetings will be open to the public for approximately...

  6. 75 FR 57833 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2010-09-22

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical... the panels of the Joint Biomedical Laboratory Research and Development and Clinical Science Research... Crowne Plaza Clinical Research Program December 3, 2010 *VA Central Office Mental Hlth & Behav Sci-A...

  7. 78 FR 22622 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2013-04-16

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical... the panels of the Joint Biomedical Laboratory Research and Development and Clinical Science Research... biomedical, behavioral and clinical science research. The panel meetings will be open to the public for...

  8. 75 FR 23847 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2010-05-04

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical... panels of the Joint Biomedical Laboratory Research and Development and Clinical Science Research and... & Behav Sci-A June 7, 2010 L'Enfant Plaza Hotel. Clinical Research Program June 9, 2010 *VA Central Office...

  9. Laboratory Directed Research and Development annual report, Fiscal year 1993

    International Nuclear Information System (INIS)

    1994-01-01

    The Department of Energy Order DOE 5000.4A establishes DOE's policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 5000.4A, LDRD is ''research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this Order. LDRD includes activities previously defined as ER ampersand D, as well as other discretionary research and development activities not provided for in a DOE program.'' Consistent with the Mission Statement and Strategic Plan provided in PNL's Institutional Plan, the LDRD investments are focused on developing new and innovative approaches in research related to our ''core competencies.'' Currently, PNL's core competencies have been identified as integrated environmental research; process technology; energy systems research. In this report, the individual summaries of Laboratory-level LDRD projects are organized according to these core competencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. A significant proportion of PNL's LDRD funds are also allocated to projects within the various research centers that are proposed by individual researchers or small research teams. The projects are described in Section 2.0. The projects described in this report represent PNL's investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. In accordance with DOE guidelines, the report provides an overview of PNL's LDRD program and the management process used for the program and project summaries for each LDRD project

  10. Laboratory Directed Research and Development annual report, Fiscal year 1993

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-01

    The Department of Energy Order DOE 5000.4A establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 5000.4A, LDRD is ``research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this Order. LDRD includes activities previously defined as ER&D, as well as other discretionary research and development activities not provided for in a DOE program.`` Consistent with the Mission Statement and Strategic Plan provided in PNL`s Institutional Plan, the LDRD investments are focused on developing new and innovative approaches in research related to our ``core competencies.`` Currently, PNL`s core competencies have been identified as integrated environmental research; process technology; energy systems research. In this report, the individual summaries of Laboratory-level LDRD projects are organized according to these core competencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. A significant proportion of PNL`s LDRD funds are also allocated to projects within the various research centers that are proposed by individual researchers or small research teams. The projects are described in Section 2.0. The projects described in this report represent PNL`s investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. In accordance with DOE guidelines, the report provides an overview of PNL`s LDRD program and the management process used for the program and project summaries for each LDRD project.

  11. LABORATORY DIRECTED RESEARCH AND DEVELOPMENT PROGRAM ASSESSMENT FOR FY 2006.

    Energy Technology Data Exchange (ETDEWEB)

    FOX,K.J.

    2006-01-01

    Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's total annual budget has averaged about $460 million. There are about 2,500 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, ''Laboratory Directed Research and Development,'' April 19,2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy National Nuclear Security Administration Laboratories dated June 13,2006. The goals and' objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new

  12. Laboratory Directed Research and Development Program Assessment for FY 2007

    Energy Technology Data Exchange (ETDEWEB)

    Newman,L.; Fox, K.J.

    2007-12-31

    Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal Year 2007 spending was $515 million. There are approximately 2,600 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development', April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology ideas, which

  13. Laboratory technology research - abstracts of FY 1997 projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of this country: the world-class basic research capability of the DOE Energy Research (ER) multi-program national laboratories and the unparalleled entrepreneurial spirit of American industry. A distinguishing feature of the ER multi-program national laboratories is their ability to integrate broad areas of science and engineering in support of national research and development goals. The LTR program leverages this strength for the Nation`s benefit by fostering partnerships with US industry. The partners jointly bring technology research to a point where industry or the Department`s technology development programs can pursue final development and commercialization. Projects supported by the LTR program are conducted by the five ER multi-program laboratories. These projects explore the applications of basic research advances relevant to DOE`s mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials; intelligent processing/manufacturing research; and sustainable environments.

  14. Tensions within an industrial research laboratory: the Philips laboratory's x-ray department between the wars

    NARCIS (Netherlands)

    Boersma, F.K.

    2003-01-01

    Tensions arose in the X-ray department of the Philips research laboratory during the interwar period, caused by the interplay among technological development, organizational culture, and individual behavior. This article traces the efforts of Philips researchers to find a balance between their

  15. Laboratory services series: the utilization of scientific glassblowing in a national research and development laboratory

    International Nuclear Information System (INIS)

    Farnham, R.M.; Poole, R.W.

    1976-04-01

    Glassblowing services at a national research and development laboratory provide unique equipment tailored for specific research efforts, small-scale process items for flowsheet demonstrations, and solutions for unusual technical problems such as glass-ceramic unions. Facilities, equipment, and personnel necessary for such services are described

  16. Laboratory directed research and development program, FY 1996

    International Nuclear Information System (INIS)

    1997-02-01

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory's forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances the Laboratory's core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. Areas eligible for support include: (1) Work in forefront areas of science and technology that enrich Laboratory research and development capability; (2) Advanced study of new hypotheses, new experiments, and innovative approaches to develop new concepts or knowledge; (3) Experiments directed toward proof of principle for initial hypothesis testing or verification; and (4) Conception and preliminary technical analysis to explore possible instrumentation, experimental facilities, or new devices

  17. GaInSn usage in the research laboratory

    International Nuclear Information System (INIS)

    Morley, N. B.; Burris, J.; Cadwallader, L. C.; Nornberg, M. D.

    2008-01-01

    GaInSn, a eutectic alloy, has been successfully used in the Magneto-Thermofluid Research Laboratory at the University of California-Los Angeles and at the Princeton Plasma Physics Laboratory for the past six years. This paper describes the handling and safety of GaInSn based on the experience gained in these institutions, augmented by observations from other researchers in the liquid metal experimental community. GaInSn is an alloy with benign properties and shows considerable potential in liquid metal experimental research and cooling applications

  18. Use of Laboratory Animals in Biomedical and Behavioral Research

    National Research Council Canada - National Science Library

    1988-01-01

    ... of Laboratory Animals in Biomedical and Behavioral Research Commission on Life Sciences National Research Council Institute of Medicine NATIONAL ACADEMY PRESS Washington, D.C. 1988 Copyrightoriginal retained, the be not from cannot book, paper original however, for version formatting, authoritative the typesetting-specific created from the as publ...

  19. Quality assurance in a large research and development laboratory

    International Nuclear Information System (INIS)

    Neill, F.H.

    1980-01-01

    Developing a quality assurance program for a large research and development laboratory provided a unique opportunity for innovative planning. The quality assurance program that emerged has been tailored to meet the requirements of several sponsoring organizations and contains the flexibility for experimental programs ranging from large engineering-scale development projects to bench-scale basic research programs

  20. Integrating Interdisciplinary Research-Based Experiences in Biotechnology Laboratories

    Science.gov (United States)

    Iyer, Rupa S.; Wales, Melinda E.

    2012-01-01

    The increasingly interdisciplinary nature of today's scientific research is leading to the transformation of undergraduate education. In addressing these needs, the University of Houston's College of Technology has developed a new interdisciplinary research-based biotechnology laboratory curriculum. Using the pesticide degrading bacterium,…

  1. U.S. Army Research Laboratory Annual Review 2011

    Science.gov (United States)

    2011-12-01

    bioremediation of wastewater. The researchers created a functional atomic circuit with stationary barrier. This “atom circuit” is composed of ultra...high energy content approaching jet propellant (JP)-8/ diesel fuel, are a means to address these demands. The Army Research Laboratory has

  2. Laboratory directed research and development. FY 1995 progress report

    Energy Technology Data Exchange (ETDEWEB)

    Vigil, J.; Prono, J. [comps.

    1996-03-01

    This document presents an overview of Laboratory Directed Research and Development Programs at Los Alamos. The nine technical disciplines in which research is described include materials, engineering and base technologies, plasma, fluids, and particle beams, chemistry, mathematics and computational science, atmic and molecular physics, geoscience, space science, and astrophysics, nuclear and particle physics, and biosciences. Brief descriptions are provided in the above programs.

  3. Field Research Studying Whales in an Undergraduate Animal Behavior Laboratory

    Science.gov (United States)

    MacLaren, R. David; Schulte, Dianna; Kennedy, Jen

    2012-01-01

    This work describes a new field research laboratory in an undergraduate animal behavior course involving the study of whale behavior, ecology and conservation in partnership with a non-profit research organization--the Blue Ocean Society for Marine Conservation (BOS). The project involves two weeks of training and five weekend trips on whale watch…

  4. Laboratory technology research: Abstracts of FY 1998 projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of the country: the world-class basic research capability of the DOE Office of Science (SC) national laboratories and the unparalleled entrepreneurial spirit of American industry. Projects supported by the LTR program in FY 1998 explore the applications of basic research advances relevant to DOE`s mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials, intelligent processing and manufacturing research, and environmental and biomedical research. Abstracts for 85 projects are contained in this report.

  5. Current safety practices in nano-research laboratories in China.

    Science.gov (United States)

    Zhang, Can; Zhang, Jing; Wang, Guoyu

    2014-06-01

    China has become a key player in the global nanotechnology field, however, no surveys have specifically examined safety practices in the Chinese nano-laboratories in depth. This study reports results of a survey of 300 professionals who work in research laboratories that handle nanomaterials in China. We recruited participants at three major nano-research laboratories (which carry out research in diverse fields such as chemistry, material science, and biology) and the nano-chemistry session of the national meeting of the Chinese Chemical Society. Results show that almost all nano-research laboratories surveyed had general safety regulations, whereas less than one third of respondents reported having nanospecific safety rules. General safety measures were in place in most surveyed nano-research laboratories, while nanospecific protective measures existed or were implemented less frequently. Several factors reported from the scientific literature including nanotoxicology knowledge gaps, technical limitations on estimating nano-exposure, and the lack of nano-occupational safety legislation may contribute to the current state of affairs. With these factors in mind and embracing the precautionary principle, we suggest strengthening or providing nanosafety training (including raising risk awareness) and establishing nanosafety guidelines in China, to better protect personnel in the nano-workplace.

  6. 77 FR 26069 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2012-05-02

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board, Notice of Meeting Amendment The... Development and Clinical Science Research and Development Services Scientific Merit Review Board have changed...

  7. 77 FR 64598 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2012-10-22

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical...) that the panels of the Joint Biomedical Laboratory Research and Development and Clinical Science... areas of biomedical, behavioral and clinical science research. The panel meetings will be open to the...

  8. A Research-Based Laboratory Course Designed to Strengthen the Research-Teaching Nexus

    Science.gov (United States)

    Parra, Karlett J.; Osgood, Marcy P.; Pappas, Donald L., Jr.

    2010-01-01

    We describe a 10-week laboratory course of guided research experiments thematically linked by topic, which had an ultimate goal of strengthening the undergraduate research-teaching nexus. This undergraduate laboratory course is a direct extension of faculty research interests. From DNA isolation, characterization, and mutagenesis, to protein…

  9. Demonstration of Supervisory Control and Data Acquisition (SCADA) Virtualization Capability in the US Army Research Laboratory (ARL)/Sustaining Base Network Assurance Branch (SBNAB) US Army Cyber Analytics Laboratory (ACAL) SCADA Hardware Testbed

    Science.gov (United States)

    2015-05-01

    application ,1 while the simulated PLC software is the open source ModbusPal Java application . When queried using the Modbus TCP protocol, ModbusPal reports...and programmable logic controller ( PLC ) components. The HMI and PLC components were instantiated with software and installed in multiple virtual...creating and capturing HMI– PLC network traffic over a 24-h period in the virtualized network and inspect the packets for errors.  Test the

  10. Research Collaborations Between Universities and Department of Defense Laboratories

    Science.gov (United States)

    2014-07-31

    Council – Resident Research Associateship (USAF/NRC-RRA) Program,” last accessed March 10, 2013, http://www.wpafb.af.mil/ library /factsheets...as CRAs and CTAs, could enable collaboration through university consortia designed to support DOD laboratory research. Such alliances would have the...university consortia , may be able to leverage partnerships that meet their collaborative research needs. 5. Increased Patent Filing Fees when Partnering

  11. Argonne National Laboratory Annual Report of Laboratory Directed Research and Development Program Activities for FY 1994

    Energy Technology Data Exchange (ETDEWEB)

    None

    1995-02-25

    The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory's R and D capabilities, and further the development of its strategic initiatives. Projects are selected from proposals for creative and innovative R and D studies which are not yet eligible for timely support through normal programmatic channels. Among the aims of the projects supported by the Program are establishment of engineering proof-of-principle; assessment of design feasibility for prospective facilities; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these projects are closely associated with major strategic thrusts of the Laboratory as described in Argonne's Five-Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne as indicated in the Laboratory's LDRD Plan for FY 1994. Project summaries of research in the following areas are included: (1) Advanced Accelerator and Detector Technology; (2) X-ray Techniques for Research in Biological and Physical Science; (3) Nuclear Technology; (4) Materials Science and Technology; (5) Computational Science and Technology; (6) Biological Sciences; (7) Environmental Sciences: (8) Environmental Control and Waste Management Technology; and (9) Novel Concepts in Other Areas.

  12. 2015 Fermilab Laboratory Directed Research & Development Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Wester, W., editor

    2015-05-26

    Fermilab is executing Laboratory Directed Research and Development (LDRD) as outlined by order DOE O 413.2B in order to enhance and realize the mission of the laboratory in a manner that also supports the laboratory’s strategic objectives and the mission of the Department of Energy. LDRD funds enable scientific creativity, allow for exploration of “high risk, high payoff” research, and allow for the demonstration of new ideas, technical concepts, and devices. LDRD also has an objective of maintaining and enhancing the scientific and technical vitality of Fermilab.

  13. 2014 Fermilab Laboratory Directed Research & Development Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Wester, W., editor

    2016-05-26

    Fermilab is executing Laboratory Directed Research and Development (LDRD) as outlined by order DOE O 413.2B in order to enhance and realize the mission of the laboratory in a manner that also supports the laboratory’s strategic objectives and the mission of the Department of Energy. LDRD funds enable scientific creativity, allow for exploration of “high risk, high payoff” research, and allow for the demonstration of new ideas, technical concepts, and devices. LDRD also has an objective of maintaining and enhancing the scientific and technical vitality of Fermilab.

  14. The waste management at research laboratories - problems and solutions

    International Nuclear Information System (INIS)

    Dellamano, Jose Claudio; Vicente, Roberto

    2011-01-01

    The radioactive management in radioactive installations must be planned and controlled. However, in the case of research laboratories, that management is compromised due to the common use of materials and installations, the lack of trained personnel and the nonexistence of clear and objective orientations by the regulator organism. Such failures cause an increasing of generated radioactive wastes and the imprecision or nonexistence of record of radioactive substances, occasioning a financial wastage, and the cancelling of licences for use of radioactive substances. This paper discusses and proposes solutions for the problems found at radioactive waste management in research laboratories

  15. Environmental survey at Lucas Heights Research Laboratories, 1989

    International Nuclear Information System (INIS)

    Hoffman, E.L.; Arthur, J.

    1990-09-01

    Results are presented of an environmental survey conducted in the neighbourhood of the Lucas Heights Research Laboratories during 1989. No radioactivity which could have originated from these laboratories was found in samples collected from possible human food chains. All low-level liquid and gaseous waste discharges were within authorised limits. The maximum possible annual dose to the general public from airborne waste during this period is estimated to be less than 0.01 millisieverts, which is one per cent of the limit for long-term exposure that is recommended by the National Health and Medical Research Council. 9 refs., 17 tabs., 2 figs

  16. Environmental survey at Lucas Heights Research Laboratories, 1990

    International Nuclear Information System (INIS)

    Hoffmann, E.L.

    1991-10-01

    Results are presented of an environmental survey conducted in the neighbourhood of the Lucas Heights Research Laboratories during 1990. No radioactivity which could have originated from these laboratories was found in samples collected from possible human food chains. All low-level liquid and gaseous waste discharges were within authorised limits. The maximum possible annual dose to the general public from airborne waste during this period is estimated to be less than 0.01 millisieverts, which is one per cent of the limit for long-term exposure that is recommended by the National Health and Medical Research Council. 11 refs., 16 tabs., 2 figs

  17. Environmental survey at Lucas Heights Research Laboratories, 1987

    International Nuclear Information System (INIS)

    Giles, M.S.; Foy, J.J.; Hoffmann, E.L.

    1989-12-01

    Results are presented of an environmental survey conducted in the neighbourhood of the Lucas Heights Research Laboratories during 1987. No radioactivity which could have originated from these laboratories was found in samples collected from possible human food chains. All low-level liquid and gaseous waste discharges were within authorized limits. The maximum possible annual dose to the general public from airborne waste during this period is estimated to be less than 0.01 millisieverts, which is one per cent of the limit for long-term exposure that is recommended by the National Health and Medical Research Council. 9 refs., 18 tabs., 2 figs

  18. Environmental survey at Lucas Heights Research Laboratories, 1984

    International Nuclear Information System (INIS)

    Giles, M.S.; Dudaitis, A.

    1986-12-01

    Results are presented of the environmental survey conducted in the neighbourhood of the Lucas Heights Research Laboratories during 1984. These results are satisfactory. No radioactivity which could have originated from these laboratories was found in samples collected from possible human food chains. All low-level liquid and gaseous waste discharges were within authorised limits. The maximum possible annual dose to the general public from airborne waste discharges during this period is estimated to be less than 0.01 millisieverts, which is one per cent of the limit for long-term exposure that is recommended by the National Health and Medical Research Council

  19. Environmental survey at the Lucas Heights Research Laboratories. 1983

    International Nuclear Information System (INIS)

    Giles, M.S.; Dudaitis, A.

    1985-12-01

    Results are presented of the environmental survey conducted in the neighbourhood of the Lucas Heights Research Laboratories during 1983. These results are satisfactory. No radioactivity which could have originated from these laboratories was found in samples collected from possible human food chains. All low-level liquid and gaseous waste discharges were within authorised limits. The maximum possible annual dose to the general public from airborne waste discharges during this period is estimated to be less than 0.01 millisieverts, which is 1 per cent of the limit for long-term exposure that is recommended by the National Health and Medical Research Council

  20. 2015 Fermilab Laboratory Directed Research & Development Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Wester, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2016-05-26

    The Fermi National Accelerator Laboratory (FNAL) is conducting a Laboratory Directed Research and Development (LDRD) program. Fiscal year 2015 represents the first full year of LDRD at Fermilab and includes seven projects approved mid-year in FY14 and six projects approved in FY15. One of the seven original projects has been completed just after the beginning of FY15. The implementation of LDRD at Fermilab is captured in the approved Fermilab 2015 LDRD Annual Program Plan. In FY15, the LDRD program represents 0.64% of Laboratory funding. The scope of the LDRD program at Fermilab will be established over the next couple of years where a portfolio of about 20 on-going projects representing approximately between 1% and 1.5% of the Laboratory funding is anticipated. This Annual Report focuses on the status of the current projects and provides an overview of the current status of LDRD at Fermilab.

  1. Smart Electronic Laboratory Notebooks for the NIST Research Environment.

    Science.gov (United States)

    Gates, Richard S; McLean, Mark J; Osborn, William A

    2015-01-01

    Laboratory notebooks have been a staple of scientific research for centuries for organizing and documenting ideas and experiments. Modern laboratories are increasingly reliant on electronic data collection and analysis, so it seems inevitable that the digital revolution should come to the ordinary laboratory notebook. The most important aspect of this transition is to make the shift as comfortable and intuitive as possible, so that the creative process that is the hallmark of scientific investigation and engineering achievement is maintained, and ideally enhanced. The smart electronic laboratory notebooks described in this paper represent a paradigm shift from the old pen and paper style notebooks and provide a host of powerful operational and documentation capabilities in an intuitive format that is available anywhere at any time.

  2. Laboratory Directed Research and Development Program FY 2007 Annual Report

    International Nuclear Information System (INIS)

    Sjoreen, Terrence P.

    2008-01-01

    The Oak Ridge National LaboratoryLaboratory Directed Research and Development (LDRD) program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries for all ORNL LDRD research activities supported during FY 2007. The associated FY 2007 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R and D) to support DOE's overarching mission to advance the national, economic, and energy security of the United States and promote scientific and technological innovation in support of that mission. As a national resource, the Laboratory also applies its capabilities and skills to specific needs of other federal agencies and customers through the DOE Work for Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at http://www.ornl.gov/. LDRD is a relatively small but vital DOE program that allows ORNL, as well as other DOE laboratories, to select a limited number of R and D projects for the purpose of: (1) maintaining the scientific and technical vitality of the Laboratory; (2) enhancing the Laboratory's ability to address future DOE missions; (3) fostering creativity and stimulating exploration of forefront science

  3. Laboratory Directed Research and Development Program FY 2005 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Sjoreen, Terrence P [ORNL

    2006-04-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2A, 'Laboratory Directed Research and Development' (January 8, 2001), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report describes all ORNL LDRD research activities supported during FY 2005 and includes final reports for completed projects and shorter progress reports for projects that were active, but not completed, during this period. The FY 2005 ORNL LDRD Self-Assessment (ORNL/PPA-2006/2) provides financial data about the FY 2005 projects and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching national security mission, which encompasses science, energy resources, environmental quality, and national nuclear security. As a national resource, the Laboratory also applies its capabilities and skills to the specific needs of other federal agencies and customers through the DOE Work For Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at . LDRD is a relatively small but vital DOE program that allows ORNL, as well as other multiprogram DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the

  4. Laboratory Directed Research and Development Program FY 2004 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Sjoreen, Terrence P [ORNL

    2005-04-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2A, 'Laboratory Directed Research and Development' (January 8, 2001), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report describes all ORNL LDRD research activities supported during FY 2004 and includes final reports for completed projects and shorter progress reports for projects that were active, but not completed, during this period. The FY 2004 ORNL LDRD Self-Assessment (ORNL/PPA-2005/2) provides financial data about the FY 2004 projects and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching national security mission, which encompasses science, energy resources, environmental quality, and national nuclear security. As a national resource, the Laboratory also applies its capabilities and skills to the specific needs of other federal agencies and customers through the DOE Work For Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at . LDRD is a relatively small but vital DOE program that allows ORNL, as well as other multiprogram DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the

  5. Laboratory Directed Research and Development Program FY 2007 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Sjoreen, Terrence P [ORNL

    2008-04-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries for all ORNL LDRD research activities supported during FY 2007. The associated FY 2007 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching mission to advance the national, economic, and energy security of the United States and promote scientific and technological innovation in support of that mission. As a national resource, the Laboratory also applies its capabilities and skills to specific needs of other federal agencies and customers through the DOE Work for Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at http://www.ornl.gov/. LDRD is a relatively small but vital DOE program that allows ORNL, as well as other DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the Laboratory; (2) enhancing the Laboratory's ability to address future DOE missions; (3) fostering creativity and stimulating

  6. Laboratory directed research and development FY98 annual report; TOPICAL

    International Nuclear Information System (INIS)

    Al-Ayat, R; Holzrichter, J

    1999-01-01

    In 1984, Congress and the Department of Energy (DOE) established the Laboratory Directed Research and Development (LDRD) Program to enable the director of a national laboratory to foster and expedite innovative research and development (R and D) in mission areas. The Lawrence Livermore National Laboratory (LLNL) continually examines these mission areas through strategic planning and shapes the LDRD Program to meet its long-term vision. The goal of the LDRD Program is to spur development of new scientific and technical capabilities that enable LLNL to respond to the challenges within its evolving mission areas. In addition, the LDRD Program provides LLNL with the flexibility to nurture and enrich essential scientific and technical competencies and enables the Laboratory to attract the most qualified scientists and engineers. The FY98 LDRD portfolio described in this annual report has been carefully structured to continue the tradition of vigorously supporting DOE and LLNL strategic vision and evolving mission areas. The projects selected for LDRD funding undergo stringent review and selection processes, which emphasize strategic relevance and require technical peer reviews of proposals by external and internal experts. These FY98 projects emphasize the Laboratory's national security needs: stewardship of the U.S. nuclear weapons stockpile, responsibility for the counter- and nonproliferation of weapons of mass destruction, development of high-performance computing, and support of DOE environmental research and waste management programs

  7. Laboratory directed research and development annual report. Fiscal year 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-02-01

    The Department of Energy Order DOE 5000.4A establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. This report represents Pacific Northwest Laboratory`s (PNL`s) LDRD report for FY 1994. During FY 1994, 161 LDRD projects were selected for support through PNL`s LDRD project selection process. Total funding allocated to these projects was $13.7 million. Consistent with the Mission Statement and Strategic Plan provided in PNL`s Institutional Plan, the LDRD investments are focused on developing new and innovative approaches in research related to our {open_quotes}core competencies.{close_quotes} Currently, PNL`s core competencies have been identified as integrated environmental research; process science and engineering; energy systems development. In this report, the individual summaries of LDRD projects (presented in Section 1.0) are organized according to these core competencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. Projects within the three core competency areas were approximately 91.4 % of total LDRD project funding at PNL in FY 1994. A significant proportion of PNL`s LDRD funds are also allocated to projects within the various research centers that are proposed by individual researchers or small research teams. Funding allocated to each of these projects is typically $35K or less. The projects described in this report represent PNL`s investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. The report provides an overview of PNL`s LDRD program, the management process used for the program, and project summaries for each LDRD project.

  8. Frederick National Laboratory Rallies to Meet Demand for Zika Vaccine | Frederick National Laboratory for Cancer Research

    Science.gov (United States)

    The Frederick National Laboratory for Cancer Research is producing another round of Zika vaccine for ongoing studies to determine the best delivery method and dosage. This will lay the groundwork for additional tests to see if the vaccine prevents i

  9. Laboratory Directed Research and Development Program Activities for FY 2008.

    Energy Technology Data Exchange (ETDEWEB)

    Looney,J.P.; Fox, K.

    2009-04-01

    Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that maintains a primary mission focus the physical sciences, energy sciences, and life sciences, with additional expertise in environmental sciences, energy technologies, and national security. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal year 2008 budget was $531.6 million. There are about 2,800 employees, and another 4,300 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development,' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Developlnent at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. Accordingly, this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2008. BNL expended $12 million during Fiscal Year 2008 in support of 69 projects. The program has two categories, the annual Open Call LDRDs and Strategic LDRDs, which combine to meet the overall objectives of the LDRD Program. Proposals are solicited annually for review and approval concurrent with the next fiscal year, October 1. For the open call for proposals, an LDRD Selection Committee, comprised of the Associate Laboratory Directors (ALDs) for the Scientific Directorates, an equal number of scientists recommended by the Brookhaven Council, plus the Assistant Laboratory Director for Policy and Strategic Planning, review the proposals submitted in response to the solicitation. The Open Can LDRD category emphasizes innovative research concepts

  10. Argonne National Laboratory: Laboratory Directed Research and Development FY 1993 program activities. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1993-12-23

    The purposes of Argonne`s Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory`s R&D capabilities, and further the development of its strategic initiatives. Projects are selected from proposals for creative and innovative R&D studies which are not yet eligible for timely support through normal programmatic channels. Among the aims of the projects supported by the Program are establishment of engineering ``proof-of-principle`` assessment of design feasibility for prospective facilities; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these projects are closely associated with major strategic thrusts of the Laboratory as described in Argonne`s Five Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne as indicated in the Laboratory LDRD Plan for FY 1993.

  11. Laboratory Directed Research and Development FY 1998 Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    John Vigil; Kyle Wheeler

    1999-04-01

    This is the FY 1998 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principle investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5) engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.

  12. The Los Alamos Scientific Laboratory - An Isolated Nuclear Research Establishment

    Energy Technology Data Exchange (ETDEWEB)

    Bradbury, Norris E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Meade, Roger Allen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-09-23

    Early in his twenty-five year career as the Director of the Los Alamos Scientific Laboratory, Norris Bradbury wrote at length about the atomic bomb and the many implications the bomb might have on the world. His themes were both technical and philosophical. In 1963, after nearly twenty years of leading the nation’s first nuclear weapons laboratory, Bradbury took the opportunity to broaden his writing. In a paper delivered to the International Atomic Energy Agency’s symposium on the “Criteria in the Selection of Sites for the Construction of Reactors and Nuclear Research Centers,” Bradbury took the opportunity to talk about the business of nuclear research and the human component of operating a scientific laboratory. This report is the transcript of his talk.

  13. Laboratory directed research and development: FY 1997 progress report

    Energy Technology Data Exchange (ETDEWEB)

    Vigil, J.; Prono, J. [comps.

    1998-05-01

    This is the FY 1997 Progress Report for the Laboratory Directed Research and Development (LDRD) program at Los Alamos National Laboratory. It gives an overview of the LDRD program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic and molecular physics and plasmas, fluids, and particle beams, (5) engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.

  14. Laboratory Directed Research and Development FY2008 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Kammeraad, J E; Jackson, K J; Sketchley, J A; Kotta, P R

    2009-03-24

    The Laboratory Directed Research and Development (LDRD) Program, authorized by Congress in 1991 and administered by the Institutional Science and Technology Office at Lawrence Livermore, is our primary means for pursuing innovative, long-term, high-risk, and potentially high-payoff research that supports the full spectrum of national security interests encompassed by the missions of the Laboratory, the Department of Energy, and National Nuclear Security Administration. The accomplishments described in this annual report demonstrate the strong alignment of the LDRD portfolio with these missions and contribute to the Laboratory's success in meeting its goals. The LDRD budget of $91.5 million for fiscal year 2008 sponsored 176 projects. These projects were selected through an extensive peer-review process to ensure the highest scientific quality and mission relevance. Each year, the number of deserving proposals far exceeds the funding available, making the selection a tough one indeed. Our ongoing investments in LDRD have reaped long-term rewards for the Laboratory and the nation. Many Laboratory programs trace their roots to research thrusts that began several years ago under LDRD sponsorship. In addition, many LDRD projects contribute to more than one mission area, leveraging the Laboratory's multidisciplinary team approach to science and technology. Safeguarding the nation from terrorist activity and the proliferation of weapons of mass destruction will be an enduring mission of this Laboratory, for which LDRD will continue to play a vital role. The LDRD Program is a success story. Our projects continue to win national recognition for excellence through prestigious awards, papers published in peer-reviewed journals, and patents granted. With its reputation for sponsoring innovative projects, the LDRD Program is also a major vehicle for attracting and retaining the best and the brightest technical staff and for establishing collaborations with

  15. Laboratory Directed Research and Development FY2008 Annual Report

    International Nuclear Information System (INIS)

    Kammeraad, J.E.; Jackson, K.J.; Sketchley, J.A.; Kotta, P.R.

    2009-01-01

    The Laboratory Directed Research and Development (LDRD) Program, authorized by Congress in 1991 and administered by the Institutional Science and Technology Office at Lawrence Livermore, is our primary means for pursuing innovative, long-term, high-risk, and potentially high-payoff research that supports the full spectrum of national security interests encompassed by the missions of the Laboratory, the Department of Energy, and National Nuclear Security Administration. The accomplishments described in this annual report demonstrate the strong alignment of the LDRD portfolio with these missions and contribute to the Laboratory's success in meeting its goals. The LDRD budget of $91.5 million for fiscal year 2008 sponsored 176 projects. These projects were selected through an extensive peer-review process to ensure the highest scientific quality and mission relevance. Each year, the number of deserving proposals far exceeds the funding available, making the selection a tough one indeed. Our ongoing investments in LDRD have reaped long-term rewards for the Laboratory and the nation. Many Laboratory programs trace their roots to research thrusts that began several years ago under LDRD sponsorship. In addition, many LDRD projects contribute to more than one mission area, leveraging the Laboratory's multidisciplinary team approach to science and technology. Safeguarding the nation from terrorist activity and the proliferation of weapons of mass destruction will be an enduring mission of this Laboratory, for which LDRD will continue to play a vital role. The LDRD Program is a success story. Our projects continue to win national recognition for excellence through prestigious awards, papers published in peer-reviewed journals, and patents granted. With its reputation for sponsoring innovative projects, the LDRD Program is also a major vehicle for attracting and retaining the best and the brightest technical staff and for establishing collaborations with universities

  16. Laboratory directed research development annual report. Fiscal year 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-05-01

    This document comprises Pacific Northwest National Laboratory`s report for Fiscal Year 1996 on research and development programs. The document contains 161 project summaries in 16 areas of research and development. The 16 areas of research and development reported on are: atmospheric sciences, biotechnology, chemical instrumentation and analysis, computer and information science, ecological science, electronics and sensors, health protection and dosimetry, hydrological and geologic sciences, marine sciences, materials science and engineering, molecular science, process science and engineering, risk and safety analysis, socio-technical systems analysis, statistics and applied mathematics, and thermal and energy systems. In addition, this report provides an overview of the research and development program, program management, program funding, and Fiscal Year 1997 projects.

  17. Fermilab a laboratory at the frontier of research

    CERN Document Server

    Gillies, James D

    2002-01-01

    Since its foundation in 1967, creeping urbanization has taken away some of Fermilab's remoteness, but the famous buffalo still roam, and farm buildings evocative of frontier America dot the landscape - appropriately for a laboratory at the high-energy frontier of modern research. Topics discussed are the Tevatron, detector upgrades, the neutrino programme, Fermilab and the LHC and the non-accelerator programme.

  18. Overview of environmental research at the Savannah River Laboratory

    International Nuclear Information System (INIS)

    Harvey, R.S.

    1977-01-01

    Research in the environmental sciences by the Savannah River Laboratory (SRL) has the general objective of improving our understanding of transport through ecosystems and functional processes within ecosystems. With increased understanding, the basis for environmental assessments can be improved for releases from the Savannah River Plant or from the power industry of the southeastern United States

  19. LBNL Laboratory Directed Research and Development Program FY2016

    Energy Technology Data Exchange (ETDEWEB)

    Ho, D.

    2017-03-01

    The Berkeley Lab Laboratory Directed Research and Development Program FY2016 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the supported projects and summarizes their accomplishments. It constitutes a part of the LDRD program planning and documentation process that includes an annual planning cycle, project selection, implementation and review.

  20. Sequim Marine Research Laboratory routine environmental measurements during CY-1978

    International Nuclear Information System (INIS)

    Houston, J.R.; Blumer, P.J.

    1979-03-01

    Environmental data collected during 1978 in the vicinity of the Marine Research Laboratory show continued compliance with all applicable state and federal regulations and furthermore show no detectable change from conditions that existed in previous years. Samples collected for radiological analysis included soil, drinking water, bay water, clams, and seaweed. Radiation dose rates at 1 meter aboveground were also measured

  1. Magnetic mirror fusion research at the Lawrence Livermore Laboratory

    International Nuclear Information System (INIS)

    Post, R.F.

    1979-01-01

    An overall view is given of progress and plans for pressing forward with mirror research at Livermore. No detail is given on any one subject, and many interesting investigations being carried out at University laboratories in the U.S. that augment and support efforts at Livermore are omitted

  2. Nuclear fuel cycle safety research at Sandia Laboratories

    International Nuclear Information System (INIS)

    Ericson, D.M. Jr.

    1978-11-01

    This paper provides a brief introduction to Sandia Laboratories and an overview of Nuclear Regulatory Commission sponsored safety research with particular emphasis on light water reactor related activities. Several experimental and analytical programs are highlighted and the range of activities of a typical staff member illustrated

  3. Laboratory directed research and development program FY 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This report compiles the annual reports of Laboratory Directed Research and Development projects supported by the Berkeley Lab. Projects are arranged under the following topical sections: (1) Accelerator and fusion research division; (2) Chemical sciences division; (3) Computing Sciences; (4) Earth sciences division; (5) Environmental energy technologies division; (6) life sciences division; (7) Materials sciences division; (8) Nuclear science division; (9) Physics division; (10) Structural biology division; and (11) Cross-divisional. A total of 66 projects are summarized.

  4. Laboratory directed research and development program FY 1997

    International Nuclear Information System (INIS)

    1998-03-01

    This report compiles the annual reports of Laboratory Directed Research and Development projects supported by the Berkeley Lab. Projects are arranged under the following topical sections: (1) Accelerator and fusion research division; (2) Chemical sciences division; (3) Computing Sciences; (4) Earth sciences division; (5) Environmental energy technologies division; (6) life sciences division; (7) Materials sciences division; (8) Nuclear science division; (9) Physics division; (10) Structural biology division; and (11) Cross-divisional. A total of 66 projects are summarized

  5. Catalog of research projects at Lawrence Berkeley Laboratory, 1985

    International Nuclear Information System (INIS)

    1985-01-01

    This Catalog has been created to aid in the transfer of technology from the Lawrence Berkeley Laboratory to potential users in industry, government, universities, and the public. The projects are listed for the following LBL groups: Accelerator and Fusion Research Division, Applied Science Division, Biology and Medicine Division, Center for Advanced Materials, Chemical Biodynamics Division, Computing Division, Earth Sciences Division, Engineering and Technical Services Division, Materials and Molecular Research Division, Nuclear Science Division, and Physics Division

  6. Naval Arctic Research Laboratory (NARL) Subsurface Containment Berm Investigation

    Science.gov (United States)

    2015-10-01

    Degree-Days CRREL Cold Regions Research and Engineering Laboratory ERDC U.S. Army Engineer Research and Development Center FWENC Foster Wheeler ...contract with the Navy, Foster Wheeler Environmental Corporation (FWENC) constructed a subsurface containment berm at the airfield of the Naval...659J91.61 ncURE 3- 3 NAVAl.. AACnC R(Sf.ARCH l,.ASORATORY POINT 9ARROW. AlASKA AS-BUILT CONTAINMENT BERM EXTENSION AND MONITORING WELLS FOSTER W

  7. Catalog of research projects at Lawrence Berkeley Laboratory, 1985

    Energy Technology Data Exchange (ETDEWEB)

    1985-01-01

    This Catalog has been created to aid in the transfer of technology from the Lawrence Berkeley Laboratory to potential users in industry, government, universities, and the public. The projects are listed for the following LBL groups: Accelerator and Fusion Research Division, Applied Science Division, Biology and Medicine Division, Center for Advanced Materials, Chemical Biodynamics Division, Computing Division, Earth Sciences Division, Engineering and Technical Services Division, Materials and Molecular Research Division, Nuclear Science Division, and Physics Division.

  8. Pump and valve research at the Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Haynes, H.D.

    1992-01-01

    Over the last several years, the Oak Ridge National Laboratory (ORNL) has carried out several aging assessments on pumps and valves under the NRC's Nuclear Plant Aging Research (NPAR) Program. In addition, ORNL has established an Advanced Diagnostic Engineering Research and Development Center (ADEC) in order to play a key role in the field of diagnostic engineering. Initial ADEC research projects have addressed problems that were identified, at least in part, by the NPAR and other NRC-sponsored programs. This paper summarizes the pump and valve related research that has been done at ORNL and describes in more detail several diagnostic techniques developed at ORNL which are new commercially available

  9. Laboratory Directed Research and Development LDRD-FY-2011

    Energy Technology Data Exchange (ETDEWEB)

    Dena Tomchak

    2012-03-01

    This report provides a summary of the research conducted at the Idaho National Laboratory (INL) during Fiscal Year (FY) 2011. This report demonstrates the types of cutting edge research the INL is performing to help ensure the nation's energy security. The research conducted under this program is aligned with our strategic direction, benefits the Department of Energy (DOE) and is in compliance with DOE order 413.2B. This report summarizes the diverse research and development portfolio with emphasis on the DOE Office of Nuclear Energy (DOE-NE) mission, encompassing both advanced nuclear science and technology and underlying technologies.

  10. Laboratory Directed Research and Development Program Activities for FY 2007.

    Energy Technology Data Exchange (ETDEWEB)

    Newman,L.

    2007-12-31

    Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal year 2007 budget was $515 million. There are about 2,600 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development', April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. In accordance this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2007. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. We explicitly indicate that research conducted under the LDRD Program should be highly innovative, and an element of high risk as to success is acceptable. In the solicitation for new proposals for Fiscal Year 2007 we especially requested innovative new projects in

  11. Shaft extension design at the Underground Research Laboratory, Pinawa, Manitoba

    International Nuclear Information System (INIS)

    Kuzyk, G.W.; Ball, A.E.

    1991-01-01

    AECL Research has constructed an underground laboratory for the research and development required for the Canadian Nuclear Fuel Waste Management Program. The experimental program in the laboratory will contribute to the assessment of the feasibility and safety of nuclear fuel waste disposal deep in stable plutonic rock. In 1988, AECL extended the shaft of the Underground Research Laboratory (URL) from the existing 255 m depth to a depth of 443 m in cooperation with the United States Department of Energy. The project, which involved carrying out research activities while excavation and construction work was in progress, required careful planning. To accommodate the research programs, full-face blasting with a burn cut was used to advance the shaft. Existing facilities at the URL had to be modified to accommodate an expanded underground facility at a new depth. This paper discusses the design criteria, shaft-sinking methods and approaches used to accommodate the research work during this shaft extension project. (11 refs., 11 figs.)

  12. Reactor safety research and development in Chalk River Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Nitheanandan, T. [Atomic Energy of Canada Limited, Chalk River, ON (Canada)

    2014-07-01

    Atomic Energy of Canada Limited's Chalk River Laboratories provides three different services to stakeholders and customers. The first service provided by the laboratory is the implementation of Research and Development (R&D) programs to provide the underlying technological basis of safe nuclear power reactor designs. A significant portion of the Canadian R&D capability in reactor safety resides at Atomic Energy of Canada Limited's Chalk River Laboratories, and this capability was instrumental in providing the science and technology required to aid in the safety design of CANDU power reactors. The second role of the laboratory has been in supporting nuclear facility licensees to ensure the continued safe operation of nuclear facilities, and to develop safety cases to justify continued operation. The licensing of plant life extension is a key industry objective, requiring extensive research on degradation mechanisms, such that safety cases are based on the original safety design data and valid and realistic assumptions regarding the effect of ageing and management of plant life. Recently, Chalk River Laboratories has been engaged in a third role in research to provide the technical basis and improved understanding for decision making by regulatory bodies. The state-of-the-art test facilities in Chalk River Laboratories have been contributing to the R&D needs of all three roles, not only in Canada but also in the international community, thorough Canada's participation in cooperative programs lead by International Atomic Energy Agency and the OECD's Nuclear Energy Agency. (author)

  13. Laboratory-Directed Research and Development 2016 Summary Annual Report

    International Nuclear Information System (INIS)

    Pillai, Rekha Sukamar; Jacobson, Julie Ann

    2017-01-01

    The Laboratory-Directed Research and Development (LDRD) Program at Idaho National Laboratory (INL) reports its status to the U.S. Department of Energy (DOE) by March of each year. The program operates under the authority of DOE Order 413.2C, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the laboratory director broad flexibility for program implementation. LDRD funds are obtained through a charge to all INL programs. This report includes summaries of all INL LDRD research activities supported during Fiscal Year (FY) 2016. INL is the lead laboratory for the DOE Office of Nuclear Energy (DOE-NE). The INL mission is to discover, demonstrate, and secure innovative nuclear energy solutions, other clean energy options, and critical infrastructure with a vision to change the world's energy future and secure our critical infrastructure. Operating since 1949, INL is the nation's leading research, development, and demonstration center for nuclear energy, including nuclear nonproliferation and physical and cyber-based protection of energy systems and critical infrastructure, as well as integrated energy systems research, development, demonstration, and deployment. INL has been managed and operated by Battelle Energy Alliance, LLC (a wholly owned company of Battelle) for DOE since 2005. Battelle Energy Alliance, LLC, is a partnership between Battelle, BWX Technologies, Inc., AECOM, the Electric Power Research Institute, the National University Consortium (Massachusetts Institute of Technology, Ohio State University, North Carolina State University, University of New Mexico, and Oregon State University), and the Idaho university collaborators (i.e., University of Idaho, Idaho State University, and Boise State University). Since its creation, INL's research and development (R&D) portfolio has broadened with targeted programs supporting national missions to advance nuclear energy, enable clean

  14. Laboratory-Directed Research and Development 2016 Summary Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Pillai, Rekha Sukamar [Idaho National Lab. (INL), Idaho Falls, ID (United States); Jacobson, Julie Ann [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-01-01

    The Laboratory-Directed Research and Development (LDRD) Program at Idaho National Laboratory (INL) reports its status to the U.S. Department of Energy (DOE) by March of each year. The program operates under the authority of DOE Order 413.2C, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the laboratory director broad flexibility for program implementation. LDRD funds are obtained through a charge to all INL programs. This report includes summaries of all INL LDRD research activities supported during Fiscal Year (FY) 2016. INL is the lead laboratory for the DOE Office of Nuclear Energy (DOE-NE). The INL mission is to discover, demonstrate, and secure innovative nuclear energy solutions, other clean energy options, and critical infrastructure with a vision to change the world’s energy future and secure our critical infrastructure. Operating since 1949, INL is the nation’s leading research, development, and demonstration center for nuclear energy, including nuclear nonproliferation and physical and cyber-based protection of energy systems and critical infrastructure, as well as integrated energy systems research, development, demonstration, and deployment. INL has been managed and operated by Battelle Energy Alliance, LLC (a wholly owned company of Battelle) for DOE since 2005. Battelle Energy Alliance, LLC, is a partnership between Battelle, BWX Technologies, Inc., AECOM, the Electric Power Research Institute, the National University Consortium (Massachusetts Institute of Technology, Ohio State University, North Carolina State University, University of New Mexico, and Oregon State University), and the Idaho university collaborators (i.e., University of Idaho, Idaho State University, and Boise State University). Since its creation, INL’s research and development (R&D) portfolio has broadened with targeted programs supporting national missions to advance nuclear energy

  15. Laboratory Directed Research and Development Program. FY 1993

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    This report is compiled from annual reports submitted by principal investigators following the close of fiscal year 1993. This report describes the projects supported and summarizes their accomplishments. The program advances the Laboratory`s core competencies, foundations, scientific capability, and permits exploration of exciting new opportunities. Reports are given from the following divisions: Accelerator and Fusion Research, Chemical Sciences, Earth Sciences, Energy and Environment, Engineering, Environment -- Health and Safety, Information and Computing Sciences, Life Sciences, Materials Sciences, Nuclear Science, Physics, and Structural Biology. (GHH)

  16. A 50-year research journey. From laboratory to clinic.

    Science.gov (United States)

    Ross, John

    2009-01-01

    Prior important research is not always cited, exemplified by Oswald Avery's pioneering discovery that DNA is the genetic transforming factor; it was not cited by Watson and Crick 10 years later. My first laboratory research (National Institutes of Health 1950s) resulted in the clinical development of transseptal left heart catheterization. Laboratory studies on cardiac muscle mechanics in normal and failing hearts led to the concept of afterload mismatch with limited preload reserve. At the University of California, San Diego in La Jolla (1968) laboratory experiments on coronary artery reperfusion after sustained coronary occlusion showed salvage of myocardial tissue, a potential treatment for acute myocardial infarction proven in clinical trials of thrombolysis 14 years later. Among 60 trainees who worked with me in La Jolla, one-third were Japanese and some of their important laboratory experiments are briefly recounted, beginning with Sasayama, Tomoike and Shirato in the 1970 s. Recently, we developed a method for cardiac gene transfer, and subsequently we showed that gene therapy for the defect in cardiomyopathic hamsters halted the progression of advanced disease. Cardiovascular research and medicine are producing continuing advances in technologies for gene transfer and embryonic stem cell transplantation, targeting of small molecules, and tissue and organ engineering.

  17. Laboratory Directed Research and Development Program FY98

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, T. [ed.; Chartock, M.

    1999-02-05

    The Ernest Orlando Lawrence Berkeley National Laboratory (LBNL or Berkeley Lab) Laboratory Directed Research and Development Program FY 1998 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the supported projects and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The LBNL LDRD program is a critical tool for directing the Laboratory's forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for LBNL scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances LBNL's core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. All projects are work in forefront areas of science and technology. Areas eligible for support include the following: Advanced study of hypotheses, concepts, or innovative approaches to scientific or technical problems; Experiments and analyses directed toward ''proof of principle'' or early determination of the utility of new scientific ideas, technical concepts, or devices; and Conception and preliminary technical analyses of experimental facilities or devices.

  18. Laboratory Directed Research and Development Program. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    Ogeka, G.J.

    1991-12-01

    Today, new ideas and opportunities, fostering the advancement of technology, are occurring at an ever-increasing rate. It, therefore, seems appropriate that a vehicle be available which fosters the development of these new ideas and technologies, promotes the early exploration and exploitation of creative and innovative concepts, and which develops new ``fundable`` R&D projects and programs. At Brookhaven National Laboratory (BNL), one such method is through its Laboratory Directed Research and Development (LDRD) Program. This discretionary research and development tool is critical in maintaining the scientific excellence and vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor achieving and maintaining staff excellence, and a means to address national needs, with the overall mission of the Department of Energy (DOE) and the Brookhaven National Laboratory. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, they have resulted in numerous publications in various professional and scientific journals, and presentations at meetings and forums.

  19. LABORATORY DIRECTED RESEARCH AND DEVELOPMENT PROGRAM ACTIVITIES FOR FY2002.

    Energy Technology Data Exchange (ETDEWEB)

    FOX,K.J.

    2002-12-31

    Brookhaven National (BNL) Laboratory is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, under contract with the U. S. Department of Energy. BNL's total annual budget has averaged about $450 million. There are about 3,000 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 4 1 3.2A, ''Laboratory Directed Research and Development,'' January 8, 2001, and the LDRD Annual Report guidance, updated February 12, 1999. The LDRD Program obtains its funds through the Laboratory overhead pool and operates under the authority of DOE Order 413.2A. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology

  20. Guidelines for euthanasia of laboratory animals used in biomedical research

    Directory of Open Access Journals (Sweden)

    Adina Baias,

    2012-06-01

    Full Text Available Laboratory animals are used in several fields of science research, especially in biology, medicine and veterinary medicine. The majority of laboratory animals used in research are experimental models that replace the human body in study regarding pharmacological or biological safety products, studies conducted for a betterunderstanding of oncologic processes, toxicology, genetic studies or even new surgical techniques. Experimental protocols include a stage in which animals are euthanized in order to remove organs and tissues,or for no unnecessary pain and suffering of animals (humane endpoints or to mark the end of research. The result of euthanasia techniques is a rapid loss of consciousness followed by cardiac arrest, respiratory arrest and disruption of brain activity. Nowadays, the accepted euthanasia techniques can use chemicals (inhalant agents like: carbon dioxide, nitrogen or argon, overdoses of injectable anesthetics or physical methods (decapitation, cervical spine dislocation, stunning, gunshot, pitching.

  1. Laboratory Directed Research and Development FY 2000 Annual Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    Los Alamos National Laboratory

    2001-05-01

    This is the FY00 Annual Progress report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes progress on each project conducted during FY00, characterizes the projects according to their relevance to major funding sources, and provides an index to principal investigators. Project summaries are grouped by LDRD component: Directed Research and Exploratory Research. Within each component, they are further grouped into the ten technical categories: (1) atomic, molecular, optical, and plasma physics, fluids, and beams, (2) bioscience, (3) chemistry, (4) computer science and software engineering, (5) engineering science, (6) geoscience, space science, and astrophysics, (7) instrumentation and diagnostics, (8) materials science, (9) mathematics, simulation, and modeling, and (10) nuclear and particle physics.

  2. Laboratory Directed Research and Development Program FY 2006

    Energy Technology Data Exchange (ETDEWEB)

    Hansen (Ed.), Todd

    2007-03-08

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness.

  3. FY2007 Laboratory Directed Research and Development Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Craig, W W; Sketchley, J A; Kotta, P R

    2008-03-20

    The Laboratory Directed Research and Development (LDRD) annual report for fiscal year 2007 (FY07) provides a summary of LDRD-funded projects for the fiscal year and consists of two parts: An introduction to the LDRD Program, the LDRD portfolio-management process, program statistics for the year, and highlights of accomplishments for the year. A summary of each project, submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to Department of Energy (DOE)/National Nuclear Security Administration (NNSA) and Lawrence Livermore National Laboratory (LLNL) mission areas, the technical progress achieved in FY07, and a list of publications that resulted from the research in FY07. Summaries are organized in sections by research category (in alphabetical order). Within each research category, the projects are listed in order of their LDRD project category: Strategic Initiative (SI), Exploratory Research (ER), Laboratory-Wide Competition (LW), and Feasibility Study (FS). Within each project category, the individual project summaries appear in order of their project tracking code, a unique identifier that consists of three elements. The first is the fiscal year the project began, the second represents the project category, and the third identifies the serial number of the proposal for that fiscal year.

  4. Radiological Characterization and Final Facility Status Report Tritium Research Laboratory

    International Nuclear Information System (INIS)

    Garcia, T.B.; Gorman, T.P.

    1996-08-01

    This document contains the specific radiological characterization information on Building 968, the Tritium Research Laboratory (TRL) Complex and Facility. We performed the characterization as outlined in its Radiological Characterization Plan. The Radiological Characterization and Final Facility Status Report (RC ampersand FFSR) provides historic background information on each laboratory within the TRL complex as related to its original and present radiological condition. Along with the work outlined in the Radiological Characterization Plan (RCP), we performed a Radiological Soils Characterization, Radiological and Chemical Characterization of the Waste Water Hold-up System including all drains, and a Radiological Characterization of the Building 968 roof ventilation system. These characterizations will provide the basis for the Sandia National Laboratory, California (SNL/CA) Site Termination Survey .Plan, when appropriate

  5. Tritium monitoring at the Sandia Tritium Research Laboratory

    International Nuclear Information System (INIS)

    Devlin, T.K.

    1978-10-01

    Sandia Laboratories at Livermore, California, is presently beginning operation of a Tritium Research Laboratory (TRL). The laboratory incorporates containment and cleanup facilities such that any unscheduled tritium release is captured rather than vented to the atmosphere. A sophisticated tritium monitoring system is in use at the TRL to protect operating personnel and the environment, as well as ensure the safe and effective operation of the TRL decontamination systems. Each monitoring system has, in addition to a local display, a display in a centralized control room which, when coupled room which, when coupled with the TRL control computer, automatically provides an immediate assessment of the status of the entire facility. The computer controls a complex alarm array status of the entire facility. The computer controls a complex alarm array and integrates and records all operational and unscheduled tritium releases

  6. Current Sandia programs and laboratory facilities for tritium research

    International Nuclear Information System (INIS)

    Swansiger, W.A.; West, L.A.

    1975-01-01

    Currently envisioned fusion reactor systems will contain substantial quantities of tritium. Strict control of the overall tritium inventory and environmental safety considerations require an accurate knowledge of the behavior of this isotope in the presence of Controlled Thermonuclear Reactor (CTR) materials. A 14,000 ft 2 laboratory for tritium research is currently under construction at Sandia Laboratories in Livermore. Details about the laboratory in general are provided. Results from studies of hydrogen isotope diffusion in surface-characterized metals will be presented. Details of two permeation systems (one for hydrogen and deuterium, the other for tritium) will be discussed. Data will also be presented concerning the gettering of hydrogen isotopes and application to CTR collector designs. (auth)

  7. The Laboratories at Seibersdorf: Multi-disciplinary research and support centre

    International Nuclear Information System (INIS)

    Danesi, P.R.

    1987-01-01

    The main research activities performed at the IAEA laboratories at Seibersdorf in the Agriculture Laboratory, Physics-Chemistry-Instrumentation Laboratory and Safeguards Analytical Laboratory, as well as the training activities are briefly described

  8. Update on Engine Combustion Research at Sandia National Laboratories

    International Nuclear Information System (INIS)

    Jay Keller; Gurpreet Singh

    2001-01-01

    The objectives of this paper are to describe the research efforts in diesel engine combustion at Sandia National Laboratories' Combustion Research Facility and to provide recent experimental results. We have four diesel engine experiments supported by the Department of Energy, Office of Heavy Vehicle Technologies: a one-cylinder version of a Cummins heavy-duty engine, a diesel simulation facility, a one-cylinder Caterpillar engine to evaluate combustion of alternative fuels, and a homogeneous-charge, compression ignition (HCCI) engine. Recent experimental results of diesel combustion research will be discussed and a description will be given of our HCCI experimental program and of our HCCI modeling work

  9. Laboratory Directed Research and Development FY2011 Annual Report

    International Nuclear Information System (INIS)

    Craig, W.; Sketchley, J.; Kotta, P.

    2012-01-01

    A premier applied-science laboratory, Lawrence Livermore National Laboratory (LLNL) has earned the reputation as a leader in providing science and technology solutions to the most pressing national and global security problems. The LDRD Program, established by Congress at all DOE national laboratories in 1991, is LLNL's most important single resource for fostering excellent science and technology for today's needs and tomorrow's challenges. The LDRD internally directed research and development funding at LLNL enables high-risk, potentially high-payoff projects at the forefront of science and technology. The LDRD Program at Livermore serves to: (1) Support the Laboratory's missions, strategic plan, and foundational science; (2) Maintain the Laboratory's science and technology vitality; (3) Promote recruiting and retention; (4) Pursue collaborations; (5) Generate intellectual property; and (6) Strengthen the U.S. economy. Myriad LDRD projects over the years have made important contributions to every facet of the Laboratory's mission and strategic plan, including its commitment to nuclear, global, and energy and environmental security, as well as cutting-edge science and technology and engineering in high-energy-density matter, high-performance computing and simulation, materials and chemistry at the extremes, information systems, measurements and experimental science, and energy manipulation. A summary of each project was submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to DOE/NNSA and LLNL mission areas, the technical progress achieved in FY11, and a list of publications that resulted from the research. The projects are: (1) Nuclear Threat Reduction; (2) Biosecurity; (3) High-Performance Computing and Simulation; (4) Intelligence; (5) Cybersecurity; (6) Energy Security; (7) Carbon Capture; (8) Material Properties, Theory, and Design; (9) Radiochemistry; (10) High-Energy-Density Science; (11) Laser Inertial

  10. Status of Avian Research at the National Renewable Energy Laboratory

    International Nuclear Information System (INIS)

    Sinclair, K.

    2001-01-01

    As the use of wind energy expands across the United States, concerns about the impacts of commercial wind farms on bird and bat populations are frequently raised. Two primary areas of concern are (1) possible litigation resulting from the killing of even one bird if it is protected by the Migratory Bird Treaty Act, the Endangered Species Act, or both; and (2) the effect of avian mortality on bird populations. To properly address these concerns, the U.S. Department of Energy's National Renewable Energy Laboratory (NREL) supports scientifically based avian/wind power interaction research. In this paper I describe NREL's field-based research projects and summarize the status of the research. I also summarize NREL's other research activities, including lab-based vision research to increase the visibility of moving turbine blades and avian acoustic research, as well as our collaborative efforts with the National Wind Coordinating Committee's Avian Subcommittee

  11. Georgia Teachers in Academic Laboratories: Research Experiences in the Geosciences

    Science.gov (United States)

    Barrett, D.

    2005-12-01

    The Georgia Intern-Fellowships for Teachers (GIFT) is a collaborative effort designed to enhance mathematics and science experiences of Georgia teachers and their students through summer research internships for teachers. By offering business, industry, public science institute and research summer fellowships to teachers, GIFT provides educators with first-hand exposure to the skills and knowledge necessary for the preparation of our future workforce. Since 1991, GIFT has placed middle and high school mathematics, science and technology teachers in over 1000 positions throughout the state. In these fellowships, teachers are involved in cutting edge scientific and engineering research, data analysis, curriculum development and real-world inquiry and problem solving, and create Action Plans to assist them in translating the experience into changed classroom practice. Since 2004, an increasing number of high school students have worked with their teachers in research laboratories. The GIFT program places an average of 75 teachers per summer into internship positions. In the summer of 2005, 83 teachers worked in corporate and research environments throughout the state of Georgia and six of these positions involved authentic research in geoscience related departments at the Georgia Institute of Technology, including aerospace engineering and the earth and atmospheric sciences laboratories. This presentation will review the history and the structure of the program including the support system for teachers and mentors as well as the emphasis on inquiry based learning strategies. The focus of the presentation will be a comparison of two placement models of the teachers placed in geoscience research laboratories: middle school earth science teachers placed in a 6 week research experience and high school teachers placed in 7 week internships with teams of 3 high school students. The presentation will include interviews with faculty to determine the value of these experiences

  12. Laboratory Directed Research and Development Program FY2004

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd C.

    2005-03-22

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Goals that are codified in DOE's September 2003 Strategic Plan, with a primary focus on Advancing Scientific Understanding. For that goal, the Fiscal Year (FY) 2004 LDRD projects support every one of the eight strategies described in the plan. In addition, LDRD efforts support the goals of Investing in America's Energy Future (six of the fourteen strategies), Resolving the Environmental Legacy (four of the eight strategies), and Meeting National Security Challenges (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD supports Office of Science strategic plans, including the 20 year Scientific Facilities Plan and the draft Office of Science Strategic Plan. The research also

  13. Argonne National Laboratory annual report of Laboratory Directed Research and Development Program Activities FY 2009.

    Energy Technology Data Exchange (ETDEWEB)

    Office of the Director

    2010-04-09

    I am pleased to submit Argonne National Laboratory's Annual Report on its Laboratory Directed Research and Development (LDRD) activities for fiscal year 2009. Fiscal year 2009 saw a heightened focus by DOE and the nation on the need to develop new sources of energy. Argonne scientists are investigating many different sources of energy, including nuclear, solar, and biofuels, as well as ways to store, use, and transmit energy more safely, cleanly, and efficiently. DOE selected Argonne as the site for two new Energy Frontier Research Centers (EFRCs) - the Institute for Atom-Efficient Chemical Transformations and the Center for Electrical Energy Storage - and funded two other EFRCs to which Argonne is a major partner. The award of at least two of the EFRCs can be directly linked to early LDRD-funded efforts. LDRD has historically seeded important programs and facilities at the lab. Two of these facilities, the Advanced Photon Source and the Center for Nanoscale Materials, are now vital contributors to today's LDRD Program. New and enhanced capabilities, many of which relied on LDRD in their early stages, now help the laboratory pursue its evolving strategic goals. LDRD has, since its inception, been an invaluable resource for positioning the Laboratory to anticipate, and thus be prepared to contribute to, the future science and technology needs of DOE and the nation. During times of change, LDRD becomes all the more vital for facilitating the necessary adjustments while maintaining and enhancing the capabilities of our staff and facilities. Although I am new to the role of Laboratory Director, my immediate prior service as Deputy Laboratory Director for Programs afforded me continuous involvement in the LDRD program and its management. Therefore, I can attest that Argonne's program adhered closely to the requirements of DOE Order 413.2b and associated guidelines governing LDRD. Our LDRD program management continually strives to be more efficient. In

  14. Argonne National Laboratory annual report of Laboratory Directed Research and Development Program Activities FY 2009

    International Nuclear Information System (INIS)

    2010-01-01

    I am pleased to submit Argonne National Laboratory's Annual Report on its Laboratory Directed Research and Development (LDRD) activities for fiscal year 2009. Fiscal year 2009 saw a heightened focus by DOE and the nation on the need to develop new sources of energy. Argonne scientists are investigating many different sources of energy, including nuclear, solar, and biofuels, as well as ways to store, use, and transmit energy more safely, cleanly, and efficiently. DOE selected Argonne as the site for two new Energy Frontier Research Centers (EFRCs) - the Institute for Atom-Efficient Chemical Transformations and the Center for Electrical Energy Storage - and funded two other EFRCs to which Argonne is a major partner. The award of at least two of the EFRCs can be directly linked to early LDRD-funded efforts. LDRD has historically seeded important programs and facilities at the lab. Two of these facilities, the Advanced Photon Source and the Center for Nanoscale Materials, are now vital contributors to today's LDRD Program. New and enhanced capabilities, many of which relied on LDRD in their early stages, now help the laboratory pursue its evolving strategic goals. LDRD has, since its inception, been an invaluable resource for positioning the Laboratory to anticipate, and thus be prepared to contribute to, the future science and technology needs of DOE and the nation. During times of change, LDRD becomes all the more vital for facilitating the necessary adjustments while maintaining and enhancing the capabilities of our staff and facilities. Although I am new to the role of Laboratory Director, my immediate prior service as Deputy Laboratory Director for Programs afforded me continuous involvement in the LDRD program and its management. Therefore, I can attest that Argonne's program adhered closely to the requirements of DOE Order 413.2b and associated guidelines governing LDRD. Our LDRD program management continually strives to be more efficient. In addition to

  15. Laboratory directed research and development program FY 1999

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd; Levy, Karin

    2000-03-08

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. This is the annual report on Laboratory Directed Research and Development (LDRD) program for FY99.

  16. Laboratory Directed Research and Development Program FY 2001

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd; Levy, Karin

    2002-03-15

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. This is the annual report on Laboratory Directed Research and Development (LDRD) program for FY01.

  17. The DOE/NOAA meteorological program at the Idaho National Engineering Laboratory

    International Nuclear Information System (INIS)

    George, D.H.

    1996-01-01

    The National Oceanic and Atmospheric Administration (NOAA) Air Resources Laboratory (ARL) has recently upgraded the U.S. Department of Energy's (DOE's) Idaho National Engineering Laboratory (INEL) Meteorological Measuring Network. This has allowed the entire service system to be modernized

  18. DESALINATION AND WATER TREATMENT RESEARCH AT SANDIA NATIONAL LABORATORIES.

    Energy Technology Data Exchange (ETDEWEB)

    Rigali, Mark J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Miller, James E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Altman, Susan J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Biedermann, Laura [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Brady, Patrick Vane. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kuzio, Stephanie P. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Nenoff, Tina M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Rempe, Susan [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-11-01

    Water is the backbone of our economy - safe and adequate supplies of water are vital for agriculture, industry, recreation, and human consumption. While our supply of water today is largely safe and adequate, we as a nation face increasing water supply challenges in the form of extended droughts, demand growth due to population increase, more stringent health-based regulation, and competing demands from a variety of users. To meet these challenges in the coming decades, water treatment technologies, including desalination, will contribute substantially to ensuring a safe, sustainable, affordable, and adequate water supply for the United States. This overview documents Sandia National Laboratories' (SNL, or Sandia) Water Treatment Program which focused on the development and demonstration of advanced water purification technologies as part of the larger Sandia Water Initiative. Projects under the Water Treatment Program include: (1) the development of desalination research roadmaps (2) our efforts to accelerate the commercialization of new desalination and water treatment technologies (known as the 'Jump-Start Program),' (3) long range (high risk, early stage) desalination research (known as the 'Long Range Research Program'), (4) treatment research projects under the Joint Water Reuse & Desalination Task Force, (5) the Arsenic Water Technology Partnership Program, (6) water treatment projects funded under the New Mexico Small Business Administration, (7) water treatment projects for the National Energy Technology Laboratory (NETL) and the National Renewable Energy Laboratory (NREL), (8) Sandia- developed contaminant-selective treatment technologies, and finally (9) current Laboratory Directed Research and Development (LDRD) funded desalination projects.

  19. 2016 Fermilab Laboratory Directed Research & Development Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Wester, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2016-05-25

    Fermilab is executing Laboratory Directed Research and Development (LDRD) as outlined by order DOE O 413.2B in order to enhance and realize the mission of the laboratory in a manner that also supports the laboratory’s strategic objectives and the mission of the Department of Energy. LDRD funds enable scientific creativity, allow for exploration of “high risk, high payoff” research, and allow for the demonstration of new ideas, technical concepts, and devices. LDRD also has an objective of maintaining and enhancing the scientific and technical vitality of Fermilab. LDRD is able to fund employee-initiated proposals that address the current strategic objectives and better position Fermilab for future mission needs. The request for such funds is made in consideration of the investment needs, affordability, and directives from DOE and Congress. Review procedures of the proposals will insure that those proposals which most address the strategic goals of the DOE and the Laboratory or which best position Fermilab for the future will be recommended to the Laboratory Director who has responsibility for approval. The execution of each approved project will be the responsibility of the Principal Investigator, PI, who will follow existing Laboratory guidelines to ensure compliance with safety, environmental, and quality assurance practices. A Laboratory Director-appointed LDRD Coordinator will work with Committees, Laboratory Management, other Fermilab Staff, and the PI’s to oversee the implementation of policies and procedures of LDRD and provide the management and execution of this Annual Program Plan. FY16 represents third fiscal year in which LDRD has existed at Fermilab. The number of preliminary proposals (117) submitted in response to the LDRD Call for Proposals indicates very strong interest of the program within the Fermilab community. The first two Calls have resulted in thirteen active LDRD projects – and it is expected that between five and seven new

  20. Environmental survey at Lucas Heights Research Laboratories, 1993

    International Nuclear Information System (INIS)

    Hoffmann, E.L.; Looz, T.

    1995-04-01

    Results are presented of the environmental survey conducted in the neighbourhood of the Lucas Heights Research Laboratories during 1993. No activity which could have originated from these laboratories was found in samples collected from possible human food chains. All low-level liquid and gaseous waste discharges were within authorised limits. The maximum possible annual dose to the general public from airborne discharges during this period is estimated to be less than 0.01 mSv, which is one per cent of the dose limit for long term exposure that is recommended by the National Health and Medical Research Council. A list of previous environmental survey reports is attached. 22 refs., 21 tabs., 4 figs

  1. Eighteenth annual risk reduction engineering laboratory research symposium

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    The Eighteenth Annual Risk Reduction Engineering Laboratory Research Symposium was held in Cincinnati, Ohio, April 14-16, 1992. The purpose of this Symposium was to present the latest significant research findings from ongoing and recently completed projects funded by the Risk Reduction Engineering Laboratory (RREL). These Proceedings are organized into two sections. Sessions A and B, which contain extended abstracts of the paper presentations. A list of poster displays is also included. Subjects include remedial action, treatment, and control technologies for waste disposal, landfill liner and cover systems, underground storage tanks, and demonstration and development of innovative/alternative treatment technologies for hazardous waste. Alternative technology subjects include thermal destruction of hazardous wastes, field evaluations, existing treatment options, emerging treatment processes, waste minimization, and biosystems for hazardous waste destruction

  2. Virtual Laboratory Enabling Collaborative Research in Applied Vehicle Technologies

    Science.gov (United States)

    Lamar, John E.; Cronin, Catherine K.; Scott, Laura E.

    2005-01-01

    The virtual laboratory is a new technology, based on the internet, that has had wide usage in a variety of technical fields because of its inherent ability to allow many users to participate simultaneously in instruction (education) or in the collaborative study of a common problem (real-world application). The leadership in the Applied Vehicle Technology panel has encouraged the utilization of this technology in its task groups for some time and its parent organization, the Research and Technology Agency, has done the same for its own administrative use. This paper outlines the application of the virtual laboratory to those fields important to applied vehicle technologies, gives the status of the effort, and identifies the benefit it can have on collaborative research. The latter is done, in part, through a specific example, i.e. the experience of one task group.

  3. Federal laboratory nondestructive testing research and development applicable to industry

    Energy Technology Data Exchange (ETDEWEB)

    Smith, S.A.; Moore, N.L.

    1987-02-01

    This document presents the results of a survey of nondestructive testing (NDT) and related sensor technology research and development (R and D) at selected federal laboratories. Objective was to identify and characterize NDT activities that could be applied to improving energy efficiency and overall productivity in US manufacturing. Numerous federally supported R and D programs were identified in areas such as acoustic emissions, eddy current, radiography, computer tomography and ultrasonics. A Preliminary Findings Report was sent to industry representatives, which generated considerable interest.

  4. Laboratory directed research and development FY91. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, S.E.; Hedman, I.; Kirvel, R.D.; McGregor, C.K. [eds.

    1991-12-31

    This review of research programs at Lawrence Livermore National Laboratory is composed of individual papers on various subjects. Broad topics of interest are: chemistry and materials science, computation, earth sciences, engineering, nuclear physics, and physics, and biology. Director`s initiatives include the development of a transgenic mouse, accelerator mass spectrometry, high-energy physics detectors, massive parallel computing, astronomical telescopes, the Kuwaiti oil fires and a compact torus accelerator. (GHH)

  5. Air Force Research Laboratory Success Stories. A Review of 2003

    Science.gov (United States)

    2003-01-01

    or non-NBC mode. The ECU can act as either a heater or an air conditioner and can be operated with a remote control. Compared to previous models...separation system, PSC is developing a motorized activation mechanism. Once completed, this will allow for virtually unlimited testing of the actual...stories in this book or on the CD-ROM, or for other technical activities in the Air Force Research Laboratory, contact TECH CONNECT at (800) 203-6451

  6. Environmental Quality Laboratory Research Report, 1985-1987

    OpenAIRE

    Brooks, Norman H.

    1988-01-01

    The Environmental Quality Laboratory at Caltech is a center for research on large-scale systems problems of natural resources and environmental quality. The principal areas of investigation at EQL are: 1. Air quality management. 2. Water resources and water quality management. 3. Control of hazardous substances in the environment. 4. Energy policy, including regulation, conservation and energy-environment tradeoffs. 5. Resources policy (other than energy); residuals m...

  7. HTGR safety research at the Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Stroh, K.R.; Anderson, C.A.; Kirk, W.L.

    1982-01-01

    This paper summarizes activities undertaken at the Los Alamos National Laboratory as part of the High-Temperature Gas-Cooled Reactor (HTGR) Safety Research Program sponsored by the US Nuclear Regulatory Commission. Technical accomplishments and analysis capabilities in six broad-based task areas are described. These tasks are: fission-product technology, primary-coolant impurities, structural investigations, safety instrumentation and control systems, accident delineation, and phenomena modeling and systems analysis

  8. Mission of mediation on planting underground research laboratories

    International Nuclear Information System (INIS)

    Bataille, C.

    1994-01-01

    France, who chose to have a strong nuclear industry, is confronted to the problem of management, treatment, storage and elimination of radioactive waste. The law defined an important research program with a study of underground storage in laboratories. Here is the report of this mission. A problem of people confidence arose; there is a difference between the great level of science or technology and the level of understanding of public opinion. The only answer brought by a democratic society is to develop information

  9. Controlled drill ampersand blast excavation at AECL's Underground Research Laboratory

    International Nuclear Information System (INIS)

    Kuzyk, G.W.; Onagi, D.P.; Thompson, P.M.

    1996-01-01

    A controlled drill and blast method has been developed and used to excavate the Underground Research Laboratory, a geotechnical facility constructed by Atomic Energy of Canada Limited (AECL) in crystalline rock. It has been demonstrated that the method can effectively reduce the excavation disturbed zone (EDZ) and is suitable for the construction of a used fuel disposal vault in the plutonic rock of the Canadian Shield

  10. Bulletin of the Research Laboratory for Nuclear Reactors

    International Nuclear Information System (INIS)

    Aritomi, Masanori

    2008-01-01

    The bulletin consists of two parts. The first part includes General Research Report. The Research Laboratory for Nuclear Reactors, Tokyo Institute of Technology has three engineering divisions such as Energy Engineering, Mass Transmutation Engineering, and System and Safety Engineering. In this part, 17 reports of Energy Engineering division, 8 reports of Mass transmutation Engineering division, 11 reports of System and Safety Engineering division are described as their activities. In addition, 3 reports of Cooperative Researches are also summarized. The second part is Special Issue about COE-INES RESEARCH REPORT 2007. In this part, 3 reports of Innovative Reactor Group, 2 reports of Innovative Nuclear Energy Utilization System Group, 3 reports of Innovative Transmutation/Separation Group, 2 reports of Relationship between Nuclear and Society Group, 1 report of RA Students in the COE-INES Captainship Educational Program are described as results to their researches. (J.P.N.)

  11. 2014 Fermilab Laboratory Directoed Research & Development Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Wester, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2016-05-26

    After initiation by the Fermilab Laboratory Director, a team from the senior Laboratory leadership and a Laboratory Directed Research and Development (LDRD) Advisory Committee developed an implementation plan for LDRD at Fermilab for the first time. This implementation was captured in the approved Fermilab 2014 LDRD Program Plan and followed directions and guidance from the Department of Energy (DOE) order, DOE O 413.2B, a “Roles, Responsibilities, and Guidelines, …” document, and examples of best practices at other DOE Office of Science Laboratories. At Fermilab, a FY14 midyear Call for Proposals was issued. A LDRD Selection Committee evaluated those proposals that were received and provided a recommendation to the Laboratory Director who approved seven LDRD projects. This Annual Report focuses on the status of those seven projects and provides an overview of the current status of LDRD at Fermilab. The seven FY14 LDRD approved projects had a date of initiation late in FY14 such that this report reflects approximately six months of effort approximately through January 2015. The progress of these seven projects, the subsequent award of six additional new projects beginning in FY15, and preparations for the issuance of the FY16 Call for Proposals indicates that LDRD is now integrated into the overall annual program at Fermilab. All indications are that LDRD is improving the scientific and technical vitality of the Laboratory and providing new, novel, or cutting edge projects carried out at the forefront of science and technology and aligned with the mission and strategic visions of Fermilab and the Department of Energy.

  12. Development of a Research-Oriented Inorganic Chemistry Laboratory Course

    Science.gov (United States)

    Vallarino, L. M.; Polo, D. L.; Esperdy, K.

    2001-02-01

    We report the development of a research-oriented, senior-level laboratory course in inorganic chemistry, which is a requirement for chemistry majors who plan to receive the ACS-approved Bachelor of Science degree and is a recommended elective for other chemistry majors. The objective of this course is to give all students the advantage of a research experience in which questions stemming from the literature lead to the formulation of hypotheses, and answers are sought through experiment. The one-semester Inorganic Chemistry Laboratory is ideal for this purpose, since for most students it represents the last laboratory experience before graduation and can assume the role of "capstone" course--a course where students are challenged to recall previously learned concepts and skills and put them into practice in the performance of an individual, original research project. The medium chosen for this teaching approach is coordination chemistry, a branch of chemistry that involves the interaction of inorganic and organic compounds and requires the use of various synthetic and analytical methods. This paper presents an outline of the course organization and requirements, examples of activities performed by the students, and a critical evaluation of the first five years' experience.

  13. CNR LARA project, Italy: Airborne laboratory for environmental research

    Science.gov (United States)

    Bianchi, R.; Cavalli, R. M.; Fiumi, L.; Marino, C. M.; Pignatti, S.

    1995-01-01

    The increasing interest for the environmental problems and the study of the impact on the environment due to antropic activity produced an enhancement of remote sensing applications. The Italian National Research Council (CNR) established a new laboratory for airborne hyperspectral imaging, the LARA Project (Laboratorio Aero per Ricerche Ambientali - Airborne Laboratory for Environmental Research), equipping its airborne laboratory, a CASA-212, mainly with the Daedalus AA5000 MIVIS (Multispectral Infrared and Visible Imaging Spectrometer) instrument. MIVIS's channels, spectral bandwidths, and locations are chosen to meet the needs of scientific research for advanced applications of remote sensing data. MIVIS can make significant contributions to solving problems in many diverse areas such as geologic exploration, land use studies, mineralogy, agricultural crop studies, energy loss analysis, pollution assessment, volcanology, forest fire management and others. The broad spectral range and the many discrete narrow channels of MIVIS provide a fine quantization of spectral information that permits accurate definition of absorption features from a variety of materials, allowing the extraction of chemical and physical information of our environment. The availability of such a hyperspectral imager, that will operate mainly in the Mediterranean area, at the present represents a unique opportunity for those who are involved in environmental studies and land-management to collect systematically large-scale and high spectral-spatial resolution data of this part of the world. Nevertheless, MIVIS deployments will touch other parts of the world, where a major interest from the international scientific community is present.

  14. ARL Summer Student Research Symposium. Volume 2: Compendium of Abstracts

    Science.gov (United States)

    2012-08-01

    photolithography and electron beam deposition. Electrical resistance and Dirac point measurements are taken in vacuum after 12 h of annealing at 373 K...range of resistances from 10–100 ohms and display excellent electrical conductance even at very low weight percents. The data indicates promising...the six early transition metal powders in Groups IV and V (i.e., Ti, Zr , and Hf; and V, Nb , and Ta) were subjected to high energy mechanical

  15. Research@ARL. Imaging & Image Processing. Volume 3, Issue 1

    Science.gov (United States)

    2014-01-01

    Cameras are so widely used that 48 hours of video data are uploaded to YouTube every minute.1 Through advancements in optics and photodetectors, cameras...the year, site characteristics, number of targets, target ranges, depression angle, speed of movement, and other related information) to perform

  16. ARL Summer Student Research Symposium Compendium of Abstracts. Volume 2

    Science.gov (United States)

    2015-12-01

    distribution is unlimited. 9 Correlation of RCAS Load Predictions for Active Flap Rotor Corle, Ethan Active devices on helicopter rotor blades show...production helicopters . Fluidic Flexible Matrix Composite (F2MC) tubes are a promising new class of high- authority, lightweight fluidic devices that can...the calibrations and for selected runs, I verified the component and product compositions using infrared spectroscopy. Using this data, I showed that

  17. Laboratory Directed Research and Development Program, FY 1992

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    This report is compiled from annual reports submitted by principal investigators following the close of the 1992 fiscal year. It describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Divisions that report include: Accelerator and Fusion Research, Chemical Sciences, Earth Sciences, Energy and Environment, Engineering, Environment and Safety and Health, Information and Computing Sciences, Life Sciences, Materials Sciences, Nuclear Science, Physics and Structural Biology.

  18. Laboratory Directed Research and Development Program, FY 1992

    International Nuclear Information System (INIS)

    1993-01-01

    This report is compiled from annual reports submitted by principal investigators following the close of the 1992 fiscal year. It describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Divisions that report include: Accelerator and Fusion Research, Chemical Sciences, Earth Sciences, Energy and Environment, Engineering, Environment and Safety and Health, Information and Computing Sciences, Life Sciences, Materials Sciences, Nuclear Science, Physics and Structural Biology

  19. 1996 Laboratory directed research and development annual report

    Energy Technology Data Exchange (ETDEWEB)

    Meyers, C.E.; Harvey, C.L.; Lopez-Andreas, L.M.; Chavez, D.L.; Whiddon, C.P. [comp.

    1997-04-01

    This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 1996. In addition to a programmatic and financial overview, the report includes progress reports from 259 individual R&D projects in seventeen categories. The general areas of research include: engineered processes and materials; computational and information sciences; microelectronics and photonics; engineering sciences; pulsed power; advanced manufacturing technologies; biomedical engineering; energy and environmental science and technology; advanced information technologies; counterproliferation; advanced transportation; national security technology; electronics technologies; idea exploration and exploitation; production; and science at the interfaces - engineering with atoms.

  20. Laboratory-directed research and development: FY 1996 progress report

    Energy Technology Data Exchange (ETDEWEB)

    Vigil, J.; Prono, J. [comps.

    1997-05-01

    This report summarizes the FY 1996 goals and accomplishments of Laboratory-Directed Research and Development (LDRD) projects. It gives an overview of the LDRD program, summarizes work done on individual research projects, and provides an index to the projects` principal investigators. Projects are grouped by their LDRD component: Individual Projects, Competency Development, and Program Development. Within each component, they are further divided into nine technical disciplines: (1) materials science, (2) engineering and base technologies, (3) plasmas, fluids, and particle beams, (4) chemistry, (5) mathematics and computational sciences, (6) atomic and molecular physics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) biosciences.

  1. Laboratory-directed research and development: FY 1996 progress report

    International Nuclear Information System (INIS)

    Vigil, J.; Prono, J.

    1997-05-01

    This report summarizes the FY 1996 goals and accomplishments of Laboratory-Directed Research and Development (LDRD) projects. It gives an overview of the LDRD program, summarizes work done on individual research projects, and provides an index to the projects' principal investigators. Projects are grouped by their LDRD component: Individual Projects, Competency Development, and Program Development. Within each component, they are further divided into nine technical disciplines: (1) materials science, (2) engineering and base technologies, (3) plasmas, fluids, and particle beams, (4) chemistry, (5) mathematics and computational sciences, (6) atomic and molecular physics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) biosciences

  2. Environmental Research Laboratories annual report for 1979 and 1980

    International Nuclear Information System (INIS)

    1981-03-01

    The Atmospheric Turbulence and Diffusion Laboratory (ATDL) research program is organized around the following subject areas: transport and diffusion over complex terrain, atmospheric turbulence and plume diffusion, and forest meteorology and climatological studies. Current research efforts involve experimental and numerical modeling studies of flow over rugged terrain, studies of transport of airborne material in and above a forest canopy, basic studies of atmospheric diffusion parameters for applications to environmental impact evaluation, plume rise studies, and scientific collaboration with personnel in DOE-funded installations, universities, and government agencies on meteorological studies in our area of expertise. Abstracts of fifty-two papers that have been published or are awaiting publication are included

  3. Radiation protection in a multi-disciplinary research laboratory

    International Nuclear Information System (INIS)

    O'Donovan, E.J.B.; Jenks, G.J.; Brighton, D.R.

    1993-01-01

    This paper describes the measures for the protection of personnel against the hazards of ionising and non-ionising radiation at the Materials Research Laboratory (MRL) in Victoria. The paper describes MRL safety and protection policy and management, and gives brief details of procedures and problems at the working level. A comparison of MRL average annual photon doses with all Governmental Research Institutions and industry is given. The good safety record of MRL is evident and shows that the radioactive protection issues are well handled. 4 figs

  4. Argonne National Laboratory Annual Report of Laboratory Directed Research and Development program activities FY 2011.

    Energy Technology Data Exchange (ETDEWEB)

    (Office of The Director)

    2012-04-25

    As a national laboratory Argonne concentrates on scientific and technological challenges that can only be addressed through a sustained, interdisciplinary focus at a national scale. Argonne's eight major initiatives, as enumerated in its strategic plan, are Hard X-ray Sciences, Leadership Computing, Materials and Molecular Design and Discovery, Energy Storage, Alternative Energy and Efficiency, Nuclear Energy, Biological and Environmental Systems, and National Security. The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel technical concepts, enhance the Laboratory's research and development (R and D) capabilities, and pursue its strategic goals. projects are selected from proposals for creative and innovative R and D studies that require advance exploration before they are considered to be sufficiently developed to obtain support through normal programmatic channels. Among the aims of the projects supported by the LDRD Program are the following: establishment of engineering proof of principle, assessment of design feasibility for prospective facilities, development of instrumentation or computational methods or systems, and discoveries in fundamental science and exploratory development.

  5. Argonne National Laboratory Annual Report of Laboratory Directed Research and Development program activities FY 2010.

    Energy Technology Data Exchange (ETDEWEB)

    (Office of The Director)

    2012-04-25

    As a national laboratory Argonne concentrates on scientific and technological challenges that can only be addressed through a sustained, interdisciplinary focus at a national scale. Argonne's eight major initiatives, as enumerated in its strategic plan, are Hard X-ray Sciences, Leadership Computing, Materials and Molecular Design and Discovery, Energy Storage, Alternative Energy and Efficiency, Nuclear Energy, Biological and Environmental Systems, and National Security. The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel technical concepts, enhance the Laboratory's research and development (R and D) capabilities, and pursue its strategic goals. projects are selected from proposals for creative and innovative R and D studies that require advance exploration before they are considered to be sufficiently developed to obtain support through normal programmatic channels. Among the aims of the projects supported by the LDRD Program are the following: establishment of engineering proof of principle, assessment of design feasibility for prospective facilities, development of instrumentation or computational methods or systems, and discoveries in fundamental science and exploratory development.

  6. Sequim Marine Research Laboratory routine environmental measurements during CY-1977

    International Nuclear Information System (INIS)

    Fix, J.J.; Blumer, P.J.

    1978-06-01

    Beginning in 1976, a routine environmental program was established at the Marine Research Laboratory (MRL) at Sequim, Washington. The program is intended to demonstrate the negligible impact of current MRL operations on the surrounding environs and to provide baseline data through which any cumulative impact could be detected. The sampling frequency is greater during the first 2 years of the program to provide sufficient initial information to allow reliable estimates of observed radionuclide concentrations and to construct a long-term sampling program. The program is designed, primarily, to determine levels of radioactivity present in selected biota in Sequim Bay. The biota were selected because of their presence near the laboratory and their capacity to concentrate trace elements. Other samples were obtained to determine the radionuclides in Sequim Bay and laboratory drinking water, as well as the ambient radiation exposure levels and surface deposition of fallout radionuclides for the laboratory area. Appendix A provides a summary of the analytical methods used. The present document includes data obtained during CY 1977 in addition to CY-1976 data published previously

  7. The monitoring system of the Tritium Research Laboratory, Sandia Laboratories, Livermore, California

    International Nuclear Information System (INIS)

    Hafner, R.S.; Westfall, D.L.; Ristau, R.D.

    1978-01-01

    Computerized tritium monitoring is now in use at the Tritium Research Laboratory (TRL). Betatec 100 tritium monitors, along with several Sandia designed accessories, have been combined with a PDP 11/40 computer to provide maximum personnel and environmental protection. Each individual monitoring system, in addition to a local display in the area of interest, has a visual/audible display in the control room. Each system is then channeled into the PDP 11/40 computer, providing immediate assessment of the status of the entire laboratory from a central location. Measurement capability ranges from uCi/m 3 levels for room air monitoring to KCi/m 3 levels for glove box and process system monitoring. The overall monitoring system and its capabilities will be presented

  8. Monitoring system of the Tritium Research Laboratory, Sandia Laboratories, Livermore, CA

    International Nuclear Information System (INIS)

    Wall, W.R.; Hafner, R.S.; Westfall, D.L.; Ristau, R.D.

    1978-11-01

    Automated tritium monitoring is now in use at the Tritium Research Laboratory (TRL). Betatec 100 tritium monitors, along with several Sandia-designed accessories, have been combined with a PDP 11/40 computer to automatically read and record tritium concentrations of room air, containment, and cleanup systems. Each individual monitoring system, in addition to a local display in the area of interest, has a visible/audible display in the control room. Each system is then channeled into the PDP 11/40 computer, providing immediate assessment of the status of the entire laboratory from a central location. Measurement capability ranges from μCi/m 3 levels for room air monitoring to kCi/m 3 levels for glove box and cleanup systems monitoring. In this report the overall monitoring system and its capabilities are discussed, with detailed descriptions given of monitors and their components

  9. The need for econometric research in laboratory animal operations.

    Science.gov (United States)

    Baker, David G; Kearney, Michael T

    2015-06-01

    The scarcity of research funding can affect animal facilities in various ways. These effects can be evaluated by examining the allocation of financial resources in animal facilities, which can be facilitated by the use of mathematical and statistical methods to analyze economic problems, a discipline known as econometrics. The authors applied econometrics to study whether increasing per diem charges had a negative effect on the number of days of animal care purchased by animal users. They surveyed animal numbers and per diem charges at 20 research institutions and found that demand for large animals decreased as per diem charges increased. The authors discuss some of the challenges involved in their study and encourage research institutions to carry out more robust econometric studies of this and other economic questions facing laboratory animal research.

  10. A 13-week research-based biochemistry laboratory curriculum.

    Science.gov (United States)

    Lefurgy, Scott T; Mundorff, Emily C

    2017-09-01

    Here, we present a 13-week research-based biochemistry laboratory curriculum designed to provide the students with the experience of engaging in original research while introducing foundational biochemistry laboratory techniques. The laboratory experience has been developed around the directed evolution of an enzyme chosen by the instructor, with mutations designed by the students. Ideal enzymes for this curriculum are able to be structurally modeled, solubly expressed, and monitored for activity by UV/Vis spectroscopy, and an example curriculum for haloalkane dehalogenase is given. Unique to this curriculum is a successful implementation of saturation mutagenesis and high-throughput screening of enzyme function, along with bioinformatics analysis, homology modeling, structural analysis, protein expression and purification, polyacrylamide gel electrophoresis, UV/Vis spectroscopy, and enzyme kinetics. Each of these techniques is carried out using a novel student-designed mutant library or enzyme variant unique to the lab team and, importantly, not described previously in the literature. Use of a well-established set of protocols promotes student data quality. Publication may result from the original student-generated hypotheses and data, either from the class as a whole or individual students that continue their independent projects upon course completion. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(5):437-448, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

  11. Zoonoses of occupational health importance in contemporary laboratory animal research.

    Science.gov (United States)

    Hankenson, F Claire; Johnston, Nancy A; Weigler, Benjamin J; Di Giacomo, Ronald F

    2003-12-01

    In contemporary laboratory animal facilities, workplace exposure to zoonotic pathogens, agents transmitted to humans from vertebrate animals or their tissues, is an occupational hazard. The primary (e.g., macaques, pigs, dogs, rabbits, mice, and rats) and secondary species (e.g., sheep, goats, cats, ferrets, and pigeons) of animals commonly used in biomedical research, as classified by the American College of Laboratory Animal Medicine, are established or potential hosts for a large number of zoonotic agents. Diseases included in this review are principally those wherein a risk to biomedical facility personnel has been documented by published reports of human cases in laboratory animal research settings, or under reasonably similar circumstances. Diseases are listed alphabetically, and each section includes information about clinical disease, transmission, occurrence, and prevention in animal reservoir species and humans. Our goal is to provide a resource for veterinarians, health-care professionals, technical staff, and administrators that will assist in the design and on-going evaluation of institutional occupational health and safety programs.

  12. CSI flight experiment projects of the Naval Research Laboratory

    Science.gov (United States)

    Fisher, Shalom

    1993-02-01

    The Naval Research Laboratory (NRL) is involved in an active program of CSI flight experiments. The first CSI flight experiment of the Naval Research Laboratory, the Low Power Atmospheric Compensation Experiment (LACE) dynamics experiment, has successfully measured vibrations of an orbiting satellite with a ground-based laser radar. The observations, made on January 7, 8 and 10, 1991, represent the first ever measurements of this type. In the tests, a narrowband heterodyne CO2 laser radar, operating at a wavelength of 10.6 microns, detected vibration induced differential-Doppler signatures of the LACE satellite. Power spectral densities of forced oscillations and modal frequencies and damping rates of free-damped vibrations were obtained and compared with finite element structural models of the LACE system. Another manifested flight experiment is the Advanced Controls Technology Experiment (ACTEX) designed to demonstrate active and passive damping with piezo-electric (PZT) sensors and actuators. This experiment was developed under the management of the Air Force Phillips Laboratory with integration of the experiment at NRL. It is to ride as a secondary, or 'piggyback,' experiment on a future Navy satellite.

  13. Radioisotope research and development at Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Peterson, E.J.

    1993-01-01

    Throughout its fifty year history, Los Alamos National Laboratory has conducted research and development in the production, isolation, purification, and application of radioactive isotopes. Initially this work supported the weapons development mission of the Laboratory. Over the years the work has evolved to support basic and applied research in many diverse fields, including nuclear medicine, biomedical studies, materials science, environmental research and the physical sciences. In the early 1970s people in the Medical Radioisotope Research Program began irradiating targets at the Los Alamos Meson Physics Facility (LAMPF) to investigate the production and recovery of medically important radioisotopes. Since then spallation production using the high intensity beam at LAMPF has become a significant source of many important radioisotopes. Los Alamos posesses other facilities with isotope production capabilities. Examples are the Omega West Reactor (OWR) and the Van de Graaf Ion Beam Facility (IBF). Historically these facilities have had limited availability for radioisotope production, but recent developments portend a significant radioisotope production mission in the future

  14. Laboratory directed research and development annual report: 2005

    International Nuclear Information System (INIS)

    2006-01-01

    This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 2005 for Sandia National Laboratories. In addition to a programmatic and financial overview, the report includes progress reports from 410 individual R and D projects in 19 categories. The categories and subheadings are: Science, Technology and Engineering (Advanced Components and Certification Engineering; Advanced Manufacturing; Biotechnology; Chemical and Earth Sciences; Computational and Information Sciences; Electronics and Photonics; Engineering Sciences; Materials Science and Technology; Pulsed Power Sciences and High Energy Density Sciences; Science and Technology Strategic Objectives); Mission Technologies (Energy and Infrastructure Assurance; Homeland Security; Military Technologies and Applications; Nonproliferation and Assessments; Grand Challanges); and Corporate Objectives (Advanced Concepts; Seniors' Council; University Collaborations)

  15. Laboratory contamination in the early period of radiation research

    International Nuclear Information System (INIS)

    Rona, E.

    1979-01-01

    Meagre records exist of the levels of contamination and human exposure encountered by those who took part in the early research on radioactive materials. In order to throw some light on the nature and extent of the problem the author presents some recollections of the conditions of the laboratories in which she worked from 1924-1940. These include the Kaiser Wilhelm Institute, the Radium Institute of Vienna and the Curie Institute. The health, radiation injuries and causes of death of some early workers are discussed. Although the effects of acute exposure were recognised early on, there was less awareness of the possible effects of chronic exposure, and lack of prompt clinical signs of injury encouraged complacency. Laboratory contamination was often seen more as a problem affecting experimental results than as a health hazard. (author)

  16. Outline of new extra high voltage research equipment at Kumatori research laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Hohki, S; Ikeda, G

    1965-01-01

    Following up the construction in 1939 of an ehv research laboratory, another new research laboratory was established at Kumatori with a ground area of 142,000 square meters. As the first stage of this construction plan, the new research equipment was installed in November 1963 and began operation. The laboratory consists of comprehensive ehv research equipment and facilities relating to atomic energy. The former includes a 6000-kV impulse voltage generator, a 1650-kV alternating current testing transformer, a 300-m overhead transmission test line, a tower strength testing facility, and other various high-power test facilities. Studies on a 400- to 500-kV overhead power transmission system and other new transmission systems are currently being conducted. The details of the construction of the ehv research equipment together with the research policy for future ehv engineering are given.

  17. Customized laboratory information management system for a clinical and research leukemia cytogenetics laboratory.

    Science.gov (United States)

    Bakshi, Sonal R; Shukla, Shilin N; Shah, Pankaj M

    2009-01-01

    We developed a Microsoft Access-based laboratory management system to facilitate database management of leukemia patients referred for cytogenetic tests in regards to karyotyping and fluorescence in situ hybridization (FISH). The database is custom-made for entry of patient data, clinical details, sample details, cytogenetics test results, and data mining for various ongoing research areas. A number of clinical research laboratoryrelated tasks are carried out faster using specific "queries." The tasks include tracking clinical progression of a particular patient for multiple visits, treatment response, morphological and cytogenetics response, survival time, automatic grouping of patient inclusion criteria in a research project, tracking various processing steps of samples, turn-around time, and revenue generated. Since 2005 we have collected of over 5,000 samples. The database is easily updated and is being adapted for various data maintenance and mining needs.

  18. Astronomy, Illumination and Heritage: the Arles-Fontvieille megalithic monuments and their implications for archaeoastronomy and world heritage

    Science.gov (United States)

    Sterling Saletta, Morgan

    2015-08-01

    Recent archaeoastronomical research at the Arles-Fontvieille monuments has important implications for establishing potential Outstanding Universal Value of megalithic monuments and establishing the credibility of archaeoastronomical sites. My discovery of seasonal light and shadow hierophanies within the Arles-Fontvieille monuments has interpretive and heritage value implications not only for these sites but for late prehistoric European monuments more generally.While horizon astronomy was very likely used for time-reckoning in the Neolithic, I argue the ‘seasonal illumination hypothesis’ is more appropriate than the ‘celestial targeting paradigm’ not only for the interpretation of the role of astronomy and cosmological symbolism in the construction of the Arles-Fontvieille monuments but also for late prehistoric European tombs with chambers and passages more generally.Multiple lines of evidence suggest a cosmologically symbolic link between houses of the living and houses of the dead in late prehistoric Europe. I will suggest that this practice originated not only in symbolic aspects of domestic dwellings, but also in functional solar orientation.If seasonal illumination was a major impetus for the orientation signatures of late prehistoric European monuments, how best to establish this? Time-lapse photography or video, while not unproblematic, is a powerful method of establishing the credibility of archaeoastronomical sites- one which has been used to great effect at monuments such as Newgrange and Stonehenge. In the past, this method was limited by the cost of equipment and the time needed to visit sites and at specific periods of time. Both of these limitations have been significantly lessened in recent years. Digital cameras have become ubiquitous. More importantly, examples of “crowd-sourcing” research problems in science provide a strategy for field documentation of sites whose level of preservation is sufficient to reveal seasonal illumination

  19. Laboratory Directed Research and Development FY2011 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Craig, W; Sketchley, J; Kotta, P

    2012-03-22

    A premier applied-science laboratory, Lawrence Livermore National Laboratory (LLNL) has earned the reputation as a leader in providing science and technology solutions to the most pressing national and global security problems. The LDRD Program, established by Congress at all DOE national laboratories in 1991, is LLNL's most important single resource for fostering excellent science and technology for today's needs and tomorrow's challenges. The LDRD internally directed research and development funding at LLNL enables high-risk, potentially high-payoff projects at the forefront of science and technology. The LDRD Program at Livermore serves to: (1) Support the Laboratory's missions, strategic plan, and foundational science; (2) Maintain the Laboratory's science and technology vitality; (3) Promote recruiting and retention; (4) Pursue collaborations; (5) Generate intellectual property; and (6) Strengthen the U.S. economy. Myriad LDRD projects over the years have made important contributions to every facet of the Laboratory's mission and strategic plan, including its commitment to nuclear, global, and energy and environmental security, as well as cutting-edge science and technology and engineering in high-energy-density matter, high-performance computing and simulation, materials and chemistry at the extremes, information systems, measurements and experimental science, and energy manipulation. A summary of each project was submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to DOE/NNSA and LLNL mission areas, the technical progress achieved in FY11, and a list of publications that resulted from the research. The projects are: (1) Nuclear Threat Reduction; (2) Biosecurity; (3) High-Performance Computing and Simulation; (4) Intelligence; (5) Cybersecurity; (6) Energy Security; (7) Carbon Capture; (8) Material Properties, Theory, and Design; (9) Radiochemistry; (10) High

  20. The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes.

    Science.gov (United States)

    Marwaha, Rituraj; Arya, Subhash B; Jagga, Divya; Kaur, Harmeet; Tuli, Amit; Sharma, Mahak

    2017-04-03

    Endocytic, autophagic, and phagocytic vesicles move on microtubule tracks to fuse with lysosomes. Small GTPases, such as Rab7 and Arl8b, recruit their downstream effectors to mediate this transport and fusion. However, the potential cross talk between these two GTPases is unclear. Here, we show that the Rab7 effector PLEKHM1 simultaneously binds Rab7 and Arl8b, bringing about clustering and fusion of late endosomes and lysosomes. We show that the N-terminal RUN domain of PLEKHM1 is necessary and sufficient for interaction with Arl8b and its subsequent localization to lysosomes. Notably, we also demonstrate that Arl8b mediates recruitment of HOPS complex to PLEKHM1-positive vesicle contact sites. Consequently, Arl8b binding to PLEKHM1 is required for its function in delivery and, therefore, degradation of endocytic and autophagic cargo in lysosomes. Finally, we also show that PLEKHM1 competes with SKIP for Arl8b binding, which dictates lysosome positioning. These findings suggest that Arl8b, along with its effectors, orchestrates lysosomal transport and fusion. © 2017 Marwaha et al.

  1. The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes

    Science.gov (United States)

    Khatter, Divya; Raina, Vivek B.; Dwivedi, Devashish; Sindhwani, Aastha; Bahl, Surbhi; Sharma, Mahak

    2015-01-01

    The homotypic fusion and protein sorting (HOPS) complex is a multi-subunit complex conserved from yeast to mammals that regulates late endosome and lysosome fusion. However, little is known about how the HOPS complex is recruited to lysosomes in mammalian cells. Here, we report that the small GTPase Arl8b, but not Rab7 (also known as RAB7A), is essential for membrane localization of the human (h)Vps41 subunit of the HOPS complex. Assembly of the core HOPS subunits to Arl8b- and hVps41-positive lysosomes is guided by their subunit–subunit interactions. RNA interference (RNAi)-mediated depletion of hVps41 resulted in the impaired degradation of EGFR that was rescued upon expression of wild-type but not an Arl8b-binding-defective mutant of hVps41, suggesting that Arl8b-dependent lysosomal localization of hVps41 is required for its endocytic function. Furthermore, we have also identified that the Arl8b effector SKIP (also known as PLEKHM2) interacts with and recruits HOPS subunits to Arl8b and kinesin-positive peripheral lysosomes. Accordingly, RNAi-mediated depletion of SKIP impaired lysosomal trafficking and degradation of EGFR. These findings reveal that Arl8b regulates the association of the human HOPS complex with lysosomal membranes, which is crucial for the function of this tethering complex in endocytic degradation. PMID:25908847

  2. The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes.

    Science.gov (United States)

    Khatter, Divya; Raina, Vivek B; Dwivedi, Devashish; Sindhwani, Aastha; Bahl, Surbhi; Sharma, Mahak

    2015-05-01

    The homotypic fusion and protein sorting (HOPS) complex is a multi-subunit complex conserved from yeast to mammals that regulates late endosome and lysosome fusion. However, little is known about how the HOPS complex is recruited to lysosomes in mammalian cells. Here, we report that the small GTPase Arl8b, but not Rab7 (also known as RAB7A), is essential for membrane localization of the human (h)Vps41 subunit of the HOPS complex. Assembly of the core HOPS subunits to Arl8b- and hVps41-positive lysosomes is guided by their subunit-subunit interactions. RNA interference (RNAi)-mediated depletion of hVps41 resulted in the impaired degradation of EGFR that was rescued upon expression of wild-type but not an Arl8b-binding-defective mutant of hVps41, suggesting that Arl8b-dependent lysosomal localization of hVps41 is required for its endocytic function. Furthermore, we have also identified that the Arl8b effector SKIP (also known as PLEKHM2) interacts with and recruits HOPS subunits to Arl8b and kinesin-positive peripheral lysosomes. Accordingly, RNAi-mediated depletion of SKIP impaired lysosomal trafficking and degradation of EGFR. These findings reveal that Arl8b regulates the association of the human HOPS complex with lysosomal membranes, which is crucial for the function of this tethering complex in endocytic degradation. © 2015. Published by The Company of Biologists Ltd.

  3. Using the Human Systems Simulation Laboratory at Idaho National Laboratory for Safety Focused Research

    Energy Technology Data Exchange (ETDEWEB)

    Joe, Jeffrey .C; Boring, Ronald L.

    2016-07-01

    Under the United States (U.S.) Department of Energy (DOE) Light Water Reactor Sustainability (LWRS) program, researchers at Idaho National Laboratory (INL) have been using the Human Systems Simulation Laboratory (HSSL) to conduct critical safety focused Human Factors research and development (R&D) for the nuclear industry. The LWRS program has the overall objective to develop the scientific basis to extend existing nuclear power plant (NPP) operating life beyond the current 60-year licensing period and to ensure their long-term reliability, productivity, safety, and security. One focus area for LWRS is the NPP main control room (MCR), because many of the instrumentation and control (I&C) system technologies installed in the MCR, while highly reliable and safe, are now difficult to replace and are therefore limiting the operating life of the NPP. This paper describes how INL researchers use the HSSL to conduct Human Factors R&D on modernizing or upgrading these I&C systems in a step-wise manner, and how the HSSL has addressed a significant gap in how to upgrade systems and technologies that are built to last, and therefore require careful integration of analog and new advanced digital technologies.

  4. Aespoe hard rock laboratory. Current research projects 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    In 1986 SKB decided to construct the Aespoe Hard Rock Laboratory (HRL) in order to provide an opportunity for research, development and demonstration in a realistic and undisturbed underground rock environment down to the depth planned for the future deep repository. The focus of current and future work is on development and testing of site characterization methods, verification of models describing the function of the natural and engineered barriers and development, testing, and demonstration of repository technology. The program has been organised so that all important steps in the development of a repository are covered, in other words the Aespoe HRL constitutes a `dress rehearsal` for the Swedish deep geological repository for spent fuel and other long-lived waste. Geoscientific investigations on Aespoe and nearby islands began in 1986. Aespoe was selected as the site for the laboratory in 1988. Construction of the facility, which reaches a depth of 460 m below the surface, began in 1990 and was completed in 1995. A major milestone had been reached in 1996 with the completion of the pre-investigation and construction phases of the Aespoe HRL. The comprehensive research conducted has permitted valuable development and verification of site characterization methods applied from the ground surface, boreholes, and underground excavations. The results of this research are summarised in the book `Aespoe Hard Rock Laboratory - 10 years of Research` published by SKB in 1996. The Operating Phase of the Aespoe HRL began in 1995 and is expected to continue for 15-20 years, that is until the first stage of the development of the Swedish deep geological repository for spent nuclear fuel is expected to be completed. A number of research projects were initiated at the start of the Operating Phase. Most of these projects have made substantial progress since then and important results have been obtained. The purpose of this brochure is to provide a brief presentation of the

  5. Aespoe hard rock laboratory. Current research projects 1998

    International Nuclear Information System (INIS)

    1998-01-01

    In 1986 SKB decided to construct the Aespoe Hard Rock Laboratory (HRL) in order to provide an opportunity for research, development and demonstration in a realistic and undisturbed underground rock environment down to the depth planned for the future deep repository. The focus of current and future work is on development and testing of site characterization methods, verification of models describing the function of the natural and engineered barriers and development, testing, and demonstration of repository technology. The program has been organised so that all important steps in the development of a repository are covered, in other words the Aespoe HRL constitutes a 'dress rehearsal' for the Swedish deep geological repository for spent fuel and other long-lived waste. Geoscientific investigations on Aespoe and nearby islands began in 1986. Aespoe was selected as the site for the laboratory in 1988. Construction of the facility, which reaches a depth of 460 m below the surface, began in 1990 and was completed in 1995. A major milestone had been reached in 1996 with the completion of the pre-investigation and construction phases of the Aespoe HRL. The comprehensive research conducted has permitted valuable development and verification of site characterization methods applied from the ground surface, boreholes, and underground excavations. The results of this research are summarised in the book 'Aespoe Hard Rock Laboratory - 10 years of Research' published by SKB in 1996. The Operating Phase of the Aespoe HRL began in 1995 and is expected to continue for 15-20 years, that is until the first stage of the development of the Swedish deep geological repository for spent nuclear fuel is expected to be completed. A number of research projects were initiated at the start of the Operating Phase. Most of these projects have made substantial progress since then and important results have been obtained. The purpose of this brochure is to provide a brief presentation of the

  6. NEW IRRADIATION RESEARCH FACILITIES AT THE ARMY NATICK LABORATORIES

    Energy Technology Data Exchange (ETDEWEB)

    Cooper, R. D.; Brynjolfsson, A.

    1963-03-15

    New facilities built by the U. S. Army for research on the preservation of food by ionizing radiation consist of a food processing and packaging facility and a radiation sources laboratory with two powerful low-energy radiation sources. One is a 1.3 million-curie Co/sup 60/ source consisting of 98 tubes each containing four doubly encapsulated Co/sup 60/ slugs. The second source is an electron linear accelerator with energy variable between 2 and 32 Mev. Research with the Co/sup 60/ source is concentrated on investigation of macroscopic and microscopic dose distribution in different materials irradiated with Co/sup 60/ gamma rays. Research with the linear accelerator is concentrated on dosimetry and photonuclear reactions. (A.G.W.)

  7. Lawrence Livermore National Laboratory FY 2016 Laboratory Directed Research and Development Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Al-Ayat, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Gard, E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sketchley, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Watkins, L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-10-16

    The LDRD annual report for FY2016 consists of two parts: The Overview. This section contains a broad description of the LDRD Program, highlights of recent accomplishments and awards, Program statistics, and the LDRD portfolio-management processes. Project Reports. Project reports are submitted by all principal investigators at the end of the fiscal year. The length and depth of the report depends on the project’s lifecycle. For projects that will be continuing the following year, the principal investigator submits a continuing project report, which is a brief update containing descriptions of the goals, scope, motivation, relevance (to DOE/NNSA and Livermore mission areas), and technical progress achieved in FY16, as well as a list of selected publications and presentations that resulted from the research. For projects that concluded in FY16, a more detailed final report is provided that is technical in nature and includes the background, objectives, scientific approach, accomplishments, and impacts on the Laboratory missions, as well as a list of publications and presentations that resulted from the research. Project reports are listed under their research topics and organized by year and type, such as exploratory research (ER), feasibility study (FS), laboratory-wide competition (LW), and strategic initiative (SI). Each project is assigned a unique tracking code, an identifier that consists of three elements. The first is the fiscal year in which the project began, the second represents the project type, and the third identifies the serial number of the project for that fiscal year. For example, 16-ERD-100 means the project is an exploratory research project that began in FY16. The three-digit number (100) represents the serial number for the project.

  8. Laboratory Directed Research and Development Annual Report for 2010

    International Nuclear Information System (INIS)

    Hughes, Pamela J.

    2011-01-01

    This report documents progress made on all LDRD-funded projects during fiscal year 2010. The projects supported by LDRD funding all have demonstrable ties to DOE missions. In addition, many of the LDRD projects are relevant to the missions of other federal agencies that sponsor work at the Laboratory. The program plays a key role in attracting the best and brightest scientific staff needed to serve the highest priority DOE mission objectives. The flexibility provided by the LDRD program allows us to make rapid decisions about projects that address emerging scientific challenges so that PNNL remains a modern research facility well into the 21st century. Individual project reports comprise the bulk of this LDRD report. The Laboratory focuses its LDRD research on scientific assets that often address more than one scientific discipline. Though multidisciplinary, each project in this report appears under one of the following primary research categories: (1) Advanced Sensors and Instrumentation; (2) Biological Sciences; (3) Chemistry; (4) Earth and Space Sciences; (5) Energy Supply and Use; and (6) Engineering and Manufacturing Processes.

  9. The Mammalian Microbiome and Its Importance in Laboratory Animal Research.

    Science.gov (United States)

    Bleich, André; Fox, James G

    2015-01-01

    In this issue are assembled 10 fascinating, well-researched papers that describe the emerging field centered on the microbiome of vertebrate animals and how these complex microbial populations play a fundamental role in shaping homeostasis of the host. The content of the papers will deal with bacteria and, because of relative paucity of information on these organisms, will not include discussions on viruses, fungus, protozoa, and parasites that colonize various animals. Dissecting the number and interactions of the 500-1000 bacterial species that can inhabit the intestines of animals is made possible by advanced DNA sequencing methods, which do not depend on whether the organism can be cultured or not. Laboratory animals, particularly rodents, have proven to be an indispensable component in not only understanding how the microbiome aids in digestion and protects the host against pathogens, but also in understanding the relationship of various species of bacteria to development of the immune system. Importantly, this research elucidates purported mechanisms for how the microbiome can profoundly affect initiation and progression of diseases such as type 1 diabetes, metabolic syndromes, obesity, autoimmune arthritis, inflammatory bowel disease, and irritable bowel syndrome. The strengths and limitations of the use of germfree mice colonized with single species of bacteria, a restricted flora, or most recently the use of human-derived microbiota are also discussed. © The Author 2015. Published by Oxford University Press on behalf of the Institute for Laboratory Animal Research. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  10. Laboratory Directed Research and Development Program FY 2008 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    editor, Todd C Hansen

    2009-02-23

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2008 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD program supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under

  11. Laboratory Directed Research and Development Program FY 2008 Annual Report

    International Nuclear Information System (INIS)

    Hansen, Todd C.

    2009-01-01

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2008 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD program supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under consideration and review by the

  12. Laboratory directed research and development annual report 2004

    International Nuclear Information System (INIS)

    Not Available

    2005-01-01

    This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 2004. In addition to a programmatic and financial overview, the report includes progress reports from 352 individual R and D projects in 15 categories. The 15 categories are: (1) Advanced Concepts; (2) Advanced Manufacturing; (3) Biotechnology; (4) Chemical and Earth Sciences; (5) Computational and Information Sciences; (6) Differentiating Technologies; (7) Electronics and Photonics; (8) Emerging Threats; (9) Energy and Critical Infrastructures; (10) Engineering Sciences; (11) Grand Challenges; (12) Materials Science and Technology; (13) Nonproliferation and Materials Control; (14) Pulsed Power and High Energy Density Sciences; and (15) Corporate Objectives

  13. Tritium research laboratory cleanup and transition project final report

    International Nuclear Information System (INIS)

    Johnson, A.J.

    1997-02-01

    This Tritium Research Laboratory Cleanup and Transition Project Final Report provides a high-level summary of this project's multidimensional accomplishments. Throughout this report references are provided for in-depth information concerning the various topical areas. Project related records also offer solutions to many of the technical and or administrative challenges that such a cleanup effort requires. These documents and the experience obtained during this effort are valuable resources to the DOE, which has more than 1200 other process contaminated facilities awaiting cleanup and reapplication or demolition

  14. Oak Ridge National Laboratory Research Reactor Experimenters' Guide

    International Nuclear Information System (INIS)

    Cagle, C.D.

    1982-10-01

    The Oak Ridge National Laboratory has three multipurpose research reactors which accommodate testing loops, target irradiations, and beam-type experiments. Since the experiments must share common or similar facilities and utilities, be designed and fabricated by the same groups, and meet the same safety criteria, certain standards for these have been developed. These standards deal only with those properties from which safety and economy of time and money can be maximized and do not relate to the intent of the experiment or quality of the data obtained. The necessity for, and the limitations of, the standards are discussed; and a compilation of general standards is included

  15. 1997 Laboratory directed research and development. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    Meyers, C.E.; Harvey, C.L.; Chavez, D.L.; Whiddon, C.P. [comps.

    1997-12-31

    This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 1997. In addition to a programmatic and financial overview, the report includes progress reports from 218 individual R&D projects in eleven categories. Theses reports are grouped into the following areas: materials science and technology; computer sciences; electronics and photonics; phenomenological modeling and engineering simulation; manufacturing science and technology; life-cycle systems engineering; information systems; precision sensing and analysis; environmental sciences; risk and reliability; national grand challenges; focused technologies; and reserve.

  16. A university hot laboratory for teaching and research

    International Nuclear Information System (INIS)

    Heinonen, O.; Miettinen, J.K.

    1976-01-01

    In small countries which have limited material and capital resources there is more need for studying and teaching reactor chemistry in universities than there is in countries with special nuclear research and training centres. A new 150-m 2 laboratory of reactor chemistry was added to the premises of the Department of Radiochemistry, University of Helsinki, in October 1975. It contains a hot area with low-pressure air-conditioning, a sanitary room, a low-activity area, and an office area. The main instrument is a mass-spectrometer MI-1309 equipped with an ion counter which is particularly useful for plutonium analysis. The laboratory can handle samples up-to 10Ci gamma-acitivity - which equals one pellet of a fuel rod - in a sealed lead cell which has an interchangeable box for alpha-active work. Pretreated samples are submitted to chemical separations in glove-boxes. Samples for alpha and mass spectroscopy are also prepared in glove-boxes. Also the laboratory is provided with fume hoods suitable for building lead shields. Radiation protection and special features typical to the university environment are discussed. Methods for verfication of contamination and protection against internal and external contamination are applied. These include air monitoring, analysis of excreta, and whole-body counting. (author)

  17. A design guide for energy-efficient research laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Wishner, N.; Chen, A.; Cook, L. [eds.; Bell, G.C.; Mills, E.; Sartor, D.; Avery, D.; Siminovitch, M.; Piette, M.A.

    1996-09-24

    This document--A Design Guide for Energy-Efficient Research Laboratories--provides a detailed and holistic framework to assist designers and energy managers in identifying and applying advanced energy-efficiency features in laboratory-type environments. The Guide fills an important void in the general literature and compliments existing in-depth technical manuals. Considerable information is available pertaining to overall laboratory design issues, but no single document focuses comprehensively on energy issues in these highly specialized environments. Furthermore, practitioners may utilize many antiquated rules of thumb, which often inadvertently cause energy inefficiency. The Guide helps its user to: introduce energy decision-making into the earliest phases of the design process, access the literature of pertinent issues, and become aware of debates and issues on related topics. The Guide does focus on individual technologies, as well as control systems, and important operational factors such as building commissioning. However, most importantly, the Guide is intended to foster a systems perspective (e.g. right sizing) and to present current leading-edge, energy-efficient design practices and principles.

  18. Assessment of three medical and research laboratories using WHO ...

    African Journals Online (AJOL)

    AFRICAN JOURNALS ONLINE (AJOL) · Journals · Advanced Search · USING AJOL ... in all three laboratories, lack of quality audit schemes by two laboratories and only one laboratory enrolled into external quality assurance schemes.

  19. Establishment of a clean chemistry laboratory at JAERI. Clean laboratory for environmental analysis and research (CLEAR)

    Energy Technology Data Exchange (ETDEWEB)

    Hanzawa, Yukiko; Magara, Masaaki; Watanabe, Kazuo [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; and others

    2003-02-01

    The JAERI has established a facility with a cleanroom: the Clean Laboratory for Environmental Analysis and Research (CLEAR). This report is an overview of the design, construction and performance evaluation of the CLEAR in the initial stage of the laboratory operation in June 2001. The CLEAR is a facility to be used for analyses of ultra trace amounts of nuclear materials in environmental samples for the safeguards, for the CTBT verification and for researches on environmental sciences. One of the special features of the CLEAR is that it meets double requirements of a cleanroom and for handling of nuclear materials. As another feature of the CLEAR, much attention was paid to the construction materials of the cleanroom for trace analysis of metal elements using considerable amounts of corrosive acids. The air conditioning and purification system, specially designed experimental equipment to provide clean work surfaces, utilities and safety systems are also demonstrated. The potential contamination from the completed cleanroom atmosphere during the analytical procedure was evaluated. It can be concluded that the CLEAR has provided a suitable condition for reliable analysis of ultra trace amounts of nuclear materials and other heavy elements in environmental samples. (author)

  20. Charged particle beam propagation studies at the Naval Research Laboratory

    International Nuclear Information System (INIS)

    Meger, R.A.; Hubbard, R.F.; Antoniades, J.A.; Fernsler, R.F.; Lampe, M.; Murphy, D.P.; Myers, M.C.; Pechacek, R.E.; Peyser, T.A.; Santos, J.; Slinker, S.P.

    1993-01-01

    The Plasma Physics Division of the Naval Research Laboratory has been performing research into the propagation of high current electron beams for 20 years. Recent efforts have focused on the stabilization of the resistive hose instability. Experiments have utilized the SuperIBEX e-beam generator (5-MeV, 100-kA, 40-ns pulse) and a 2-m diameter, 5-m long propagation chamber. Full density air propagation experiments have successfully demonstrated techniques to control the hose instability allowing stable 5-m transport of 1-2 cm radius, 10-20 kA total current beams. Analytic theory and particle simulations have been used to both guide and interpret the experimental results. This paper will provide background on the program and summarize the achievements of the NRL propagation program up to this point. Further details can be found in other papers presented in this conference

  1. Environmental and effluent monitoring at Lucas Heights Research Laboratories, 1994

    International Nuclear Information System (INIS)

    Hoffmann, E.L.; Camilleri, A.; Loosz, T.; Farrar, Y.

    1995-12-01

    Results are presented of environmental and effluent monitoring conducted in the vicinity of the Lucas Heights Research Laboratories (LHRL) during 1994. All low level liquid and gaseous effluent discharges complied with existing discharge authorisations and relevant environmental regulations. Potential effective doses to the general public from controlled airborne discharges during this period, were estimated to be less than 0.015 mSv/year for receptor locations on the 1.6 km buffer zone boundary around HIFAR. This value represents 1.5 % of the 1 mSv/year dose limit for long term exposure that is recommended by the National Health and Medical Research Council, and 5 % of the site dose constraint of 0.3 mSv/year adopted by ANSTO. 27 refs., 22 tabs., 6 figs

  2. Radioactive waste management research at CEGB Berkeley nuclear laboratories

    International Nuclear Information System (INIS)

    Bradbury, D.

    1988-01-01

    The CEGB is the major electric utility in the United Kingdom. This paper discusses how, at the research laboratories at Berkeley (BNL), several programs of work are currently taking place in the radioactive waste management area. The theme running through all this work is the safe isolation of radionuclides from the environment. Normally this means disposal of waste in solid form, but it may also be desirable to segregate and release nonradioactive material from the waste to reduce volume or improve the solid waste characteristics (e.g., the release of liquid or gaseous effluents after treatment to convert the radioactivity to solid form). The fuel cycle and radioactive waste section at BNL has a research program into these aspects for wastes arising from the operation or decommissioning of power stations. The work is done both in-house and on contract, with primarily the UKAEA

  3. UTRaLab – Urban Traffic Research Laboratory

    Directory of Open Access Journals (Sweden)

    Karsten Kozempel

    2017-08-01

    Full Text Available The Urban Traffic Research Laboratory (UTRaLab is a research and test track for traffic detection methods and sensors. It is located at the Ernst-Ruska-Ufer, in the southeast of the city of Berlin (Germany. The UTRaLab covers 1 km of a highly-frequented urban road and is connected to a motorway. It is equipped with two gantries with distance of 850 m in between and has several outstations for data collection. The gantries contain many different traffic sensors like inductive loops, cameras, lasers or wireless sensors for traffic data acquisition. Additionally a weather station records environmental data. The UTRaLab’s main purposes are the data collection of traffic data on the one hand and testing newly developed sensors on the other hand.

  4. Environmental and effluent monitoring at Lucas Heights Research Laboratories, 1994

    Energy Technology Data Exchange (ETDEWEB)

    Hoffmann, E L; Camilleri, A; Loosz, T; Farrar, Y

    1995-12-01

    Results are presented of environmental and effluent monitoring conducted in the vicinity of the Lucas Heights Research Laboratories (LHRL) during 1994. All low level liquid and gaseous effluent discharges complied with existing discharge authorisations and relevant environmental regulations. Potential effective doses to the general public from controlled airborne discharges during this period, were estimated to be less than 0.015 mSv/year for receptor locations on the 1.6 km buffer zone boundary around HIFAR. This value represents 1.5 % of the 1 mSv/year dose limit for long term exposure that is recommended by the National Health and Medical Research Council, and 5 % of the site dose constraint of 0.3 mSv/year adopted by ANSTO. 27 refs., 22 tabs., 6 figs.

  5. Tungsten alloy research at the US Army Materials Technology Laboratory

    International Nuclear Information System (INIS)

    Dowding, R.J.

    1991-01-01

    This paper reports that recent research into tungsten heavy alloys at the U. S. Army Materials Technology Laboratory (MTL) has explored many areas of processing and process development. The recrystallization and respheroidization of tungsten grains in a heavily cold worked heavy alloy has been examined and resulted in the identification of a method of grain refinement. Another area of investigation has been lightly cold worked. It was determined that it was possible to increase the strength and hardness of the tungsten grains by proper hat treatment. MTL has been involved in the Army's small business innovative research (SBIR) program and several programs have been funded. Included among these are a method of coating the tungsten powders with the alloying elements and the development of techniques of powder injection molding of heavy alloys

  6. Multi-modal virtual environment research at Armstrong Laboratory

    Science.gov (United States)

    Eggleston, Robert G.

    1995-01-01

    One mission of the Paul M. Fitts Human Engineering Division of Armstrong Laboratory is to improve the user interface for complex systems through user-centered exploratory development and research activities. In support of this goal, many current projects attempt to advance and exploit user-interface concepts made possible by virtual reality (VR) technologies. Virtual environments may be used as a general purpose interface medium, an alternative display/control method, a data visualization and analysis tool, or a graphically based performance assessment tool. An overview is given of research projects within the division on prototype interface hardware/software development, integrated interface concept development, interface design and evaluation tool development, and user and mission performance evaluation tool development.

  7. Behavioral Economic Laboratory Research in Tobacco Regulatory Science.

    Science.gov (United States)

    Tidey, Jennifer W; Cassidy, Rachel N; Miller, Mollie E; Smith, Tracy T

    2016-10-01

    Research that can provide a scientific foundation for the United States Food and Drug Administration (FDA) tobacco policy decisions is needed to inform tobacco regulatory policy. One factor that affects the impact of a tobacco product on public health is its intensity of use, which is determined, in part, by its abuse liability or reinforcing efficacy. Behavioral economic tasks have considerable utility for assessing the reinforcing efficacy of current and emerging tobacco products. This paper provides a narrative review of several behavioral economic laboratory tasks and identifies important applications to tobacco regulatory science. Behavioral economic laboratory assessments, including operant self-administration, choice tasks and purchase tasks, can be used generate behavioral economic data on the effect of price and other constraints on tobacco product consumption. These tasks could provide an expedited simulation of the effects of various tobacco control policies across populations of interest to the FDA. Tobacco regulatory research questions that can be addressed with behavioral economic tasks include assessments of the impact of product characteristics on product demand, assessments of the abuse liability of novel and potential modified risk tobacco products (MRTPs), and assessments of the impact of conventional and novel products in vulnerable populations.

  8. Laboratory Directed Research and Development 1998 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Pam Hughes; Sheila Bennett eds.

    1999-07-14

    The Laboratory's Directed Research and Development (LDRD) program encourages the advancement of science and the development of major new technical capabilities from which future research and development will grow. Through LDRD funding, Pacific Northwest continually replenishes its inventory of ideas that have the potential to address major national needs. The LDRD program has enabled the Laboratory to bring to bear its scientific and technical capabilities on all of DOE's missions, particularly in the arena of environmental problems. Many of the concepts related to environmental cleanup originally developed with LDRD funds are now receiving programmatic support from DOE, LDRD-funded work in atmospheric sciences is now being applied to DOE's Atmospheric Radiation Measurement Program. We also have used concepts initially explored through LDRD to develop several winning proposals in the Environmental Management Science Program. The success of our LDRD program is founded on good management practices that ensure funding is allocated and projects are conducted in compliance with DOE requirements. We thoroughly evaluate the LDRD proposals based on their scientific and technical merit, as well as their relevance to DOE's programmatic needs. After a proposal is funded, we assess progress annually using external peer reviews. This year, as in years past, the LDRD program has once again proven to be the major enabling vehicle for our staff to formulate new ideas, advance scientific capability, and develop potential applications for DOE's most significant challenges.

  9. Laboratory Directed Research and Development Program FY2011

    Energy Technology Data Exchange (ETDEWEB)

    none, none

    2012-04-27

    Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2011 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). Going forward in FY 2012, the LDRD program also supports the Goals codified in the new DOE Strategic Plan of May, 2011. The LDRD program also supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under consideration and review by the Office of Science Program Offices, such as LDRD projects germane to new research facility concepts and new fundamental science directions. Brief summares of projects and accomplishments for the period for each division are included.

  10. Transportable Heavy Duty Emissions Testing Laboratory and Research Program

    Energy Technology Data Exchange (ETDEWEB)

    David Lyons

    2008-03-31

    The objective of this program was to quantify the emissions from heavy-duty vehicles operating on alternative fuels or advanced fuel blends, often with novel engine technology or aftertreatment. In the first year of the program West Virginia University (WVU) researchers determined that a transportable chassis dynamometer emissions measurement approach was required so that fleets of trucks and buses did not need to be ferried across the nation to a fixed facility. A Transportable Heavy-Duty Vehicle Emissions Testing Laboratory (Translab) was designed, constructed and verified. This laboratory consisted of a chassis dynamometer semi-trailer and an analytic trailer housing a full scale exhaust dilution tunnel and sampling system which mimicked closely the system described in the Code of Federal Regulations for engine certification. The Translab was first used to quantify emissions from natural gas and methanol fueled transit buses, and a second Translab unit was constructed to satisfy research demand. Subsequent emissions measurement was performed on trucks and buses using ethanol, Fischer-Tropsch fuel, and biodiesel. A medium-duty chassis dynamometer was also designed and constructed to facilitate research on delivery vehicles in the 10,000 to 20,000lb range. The Translab participated in major programs to evaluate low-sulfur diesel in conjunction with passively regenerating exhaust particulate filtration technology, and substantial reductions in particulate matter were recorded. The researchers also participated in programs to evaluate emissions from advanced natural gas engines with closed loop feedback control. These natural gas engines showed substantially reduced levels of oxides of nitrogen. For all of the trucks and buses characterized, the levels of carbon monoxide, oxides of nitrogen, hydrocarbons, carbon dioxide and particulate matter were quantified, and in many cases non-regulated species such as aldehydes were also sampled. Particle size was also

  11. Engineered nanomaterials: toward effective safety management in research laboratories.

    Science.gov (United States)

    Groso, Amela; Petri-Fink, Alke; Rothen-Rutishauser, Barbara; Hofmann, Heinrich; Meyer, Thierry

    2016-03-15

    It is still unknown which types of nanomaterials and associated doses represent an actual danger to humans and environment. Meanwhile, there is consensus on applying the precautionary principle to these novel materials until more information is available. To deal with the rapid evolution of research, including the fast turnover of collaborators, a user-friendly and easy-to-apply risk assessment tool offering adequate preventive and protective measures has to be provided. Based on new information concerning the hazards of engineered nanomaterials, we improved a previously developed risk assessment tool by following a simple scheme to gain in efficiency. In the first step, using a logical decision tree, one of the three hazard levels, from H1 to H3, is assigned to the nanomaterial. Using a combination of decision trees and matrices, the second step links the hazard with the emission and exposure potential to assign one of the three nanorisk levels (Nano 3 highest risk; Nano 1 lowest risk) to the activity. These operations are repeated at each process step, leading to the laboratory classification. The third step provides detailed preventive and protective measures for the determined level of nanorisk. We developed an adapted simple and intuitive method for nanomaterial risk management in research laboratories. It allows classifying the nanoactivities into three levels, additionally proposing concrete preventive and protective measures and associated actions. This method is a valuable tool for all the participants in nanomaterial safety. The users experience an essential learning opportunity and increase their safety awareness. Laboratory managers have a reliable tool to obtain an overview of the operations involving nanomaterials in their laboratories; this is essential, as they are responsible for the employee safety, but are sometimes unaware of the works performed. Bringing this risk to a three-band scale (like other types of risks such as biological, radiation

  12. Synthesized research report in the second mid-term research phase. Mizunami Underground Research Laboratory project, Horonobe Underground Research Laboratory project and geo-stability project (Translated document)

    International Nuclear Information System (INIS)

    Hama, Katsuhiro; Sasao, Eiji; Iwatsuki, Teruki; Onoe, Hironori; Sato, Toshinori; Yasue, Kenichi; Asamori, Koichi; Niwa, Masakazu; Osawa, Hideaki; Nagae, Isako; Natsuyama, Ryoko; Fujita, Tomoo; Sasamoto, Hiroshi; Matsuoka, Toshiyuki; Takeda, Masaki; Aoyagi, Kazuhei; Nakayama, Masashi; Miyakawa, Kazuya; Ito, Hiroaki; Ohyama, Takuya; Senba, Takeshi; Amano, Kenji

    2016-08-01

    We have synthesized the research results from the Mizunami/Horonobe Underground Research Laboratories (URLs) and geo-stability projects in the second mid-term research phase. This report can be used as a technical basis for the Nuclear Waste Management Organization of Japan/Regulator at each decision point from siting to beginning of disposal (Principal Investigation to Detailed Investigation Phase). High-quality construction techniques and field investigation methods have been developed and implemented, which will be directly applicable to the National Disposal Program (together with general assessments of hazardous natural events and processes). Acquisition of technical knowledge on decisions of partial backfilling and final closure from actual field experiments in the Mizunami/Horonobe URLs will be crucial as the main theme for the next phases. (author)

  13. Research reactor usage at the Idaho National Engineering Laboratory in support of university research and education

    International Nuclear Information System (INIS)

    Woodall, D.M.; Dolan, T.J.; Stephens, A.G.

    1990-01-01

    The Idaho National Engineering Laboratory is a US Department of Energy laboratory which has a substantial history of research and development in nuclear reactor technologies. There are a number of available nuclear reactor facilities which have been incorporated into the research and training needs of university nuclear engineering programs. This paper addresses the utilization of the Advanced Reactivity Measurement Facility (ARMF) and the Coupled Fast Reactivity Measurement Facility (CFRMF) for thesis and dissertation research in the PhD program in Nuclear Science and Engineering by the University of Idaho and Idaho State University. Other reactors at the INEL are also being used by various members of the academic community for thesis and dissertation research, as well as for research to advance the state of knowledge in innovative nuclear technologies, with the EBR-II facility playing an essential role in liquid metal breeder reactor research. 3 refs

  14. Laboratory directed research and development program FY 2003

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd

    2004-03-27

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. In FY03, Berkeley Lab was authorized by DOE to establish a funding ceiling for the LDRD program of $15.0 M, which equates to about 3.2% of Berkeley Lab's FY03 projected operating and capital equipment budgets. This funding level was provided to develop new scientific ideas and opportunities and allow the Berkeley Lab Director an opportunity to initiate new directions. Budget constraints limited available resources, however, so only $10.1 M was expended for operating and $0.6 M for capital equipment (2.4% of actual Berkeley Lab FY03 costs). In FY03, scientists submitted 168 proposals, requesting over $24.2 M in operating funding. Eighty-two projects were funded, with awards ranging from $45 K to $500 K. These projects are summarized in Table 1.

  15. Mizunami Underground Research Laboratory project. Plan for fiscal year 2017

    International Nuclear Information System (INIS)

    Ishibashi, Masayuki; Hama, Katsuhiro; Iwatsuki, Teruki; Matsui, Hiroya; Takeuchi, Ryuji; Ikeda, Koki; Mikake, Shinichiro; Iyatomi, Yosuke; Sasao, Eiji; Koide, Kaoru

    2017-10-01

    The Mizunami Underground Research Laboratory (MIU) Project is being pursued by the Japan Atomic Energy Agency (JAEA) to enhance the reliability of geological disposal technologies through investigations of the deep geological environment in the crystalline host rock (granite) at Mizunami, Gifu Prefecture, central Japan. On the occasion of the reform of the entire JAEA organization in 2014, JAEA identified three important issues on the geoscientific research program: 'Development of countermeasure technologies for reducing groundwater inflow', 'Development of modelling technologies for mass transport' and 'Development of drift backfilling technology', based on the latest results of the synthesizing research and development (R and D). The R and D on three remaining important issues has been carrying out on the MIU Project. This report summarizes the R and D activities planned for fiscal year 2017 on the basis of the MIU Master Plan updated in 2015 and Investigation Plan for the Third Medium to Long-term Research Phase. (author)

  16. AECL's underground research laboratory: technical achievements and lessons learned

    International Nuclear Information System (INIS)

    Ohta, M.M.; Chandler, N.A.

    1997-03-01

    During the development of the research program for the Canadian Nuclear Fuel Waste Management Program in the 1970's, the need for an underground facility was recognized. AECL constructed an Underground Research Laboratory (URL) for large-scale testing and in situ engineering and performance-assessment-related experiments on key aspects of deep geological disposal in a representative geological environment. Ale URL is a unique geotechnical research and development facility because it was constructed in a previously undisturbed portion of a granitic pluton that was well characterized before construction began, and because most of the shaft and experimental areas are below the water table. The specific areas of research, development and demonstration include surface and underground characterization; groundwater and solute transport; in situ rock stress conditions; temperature and time-dependent deformation and failure characteristics of rock; excavation techniques to minimize damage to surrounding rock and to ensure safe working conditions; and the performance of seals and backfills. This report traces the evolution of the URL and summarizes the technical achievements and lessons learned during its siting, design and construction, and operating phases over the last 18 years. (author)

  17. Development of excavation technologies at the Canadian underground research laboratory

    International Nuclear Information System (INIS)

    Kuzyk, Gregory W.; Martino, Jason B.

    2008-01-01

    Several countries, Canada being among them, are developing concepts for disposal of used fuel from power generating nuclear reactors. As in underground mining operations, the disposal facilities will require excavation of many kilometres of shafts and tunnels through the host rock mass. The need to maintain the stability of excavations and safety of workers will be of paramount importance. Also, excavations required for many radioactive waste repositories will ultimately need to be backfilled and sealed to maintain stability and minimize any potential for migration of radionuclides, should they escape their disposal containers. The method used to excavate the tunnels and shafts, and the rock damage that occurs due to excavation, will greatly affect the performance characteristics of repository sealing systems. The underground rock mechanics and geotechnical engineering work performed at the Canadian Underground Research Laboratory (URL) has led to the development of excavation technologies that reduce rock damage in subsurface excavations. This paper discusses the excavation methods used to construct the URL and their application in planning for the construction of similar underground laboratories and repositories for radioactive wastes. (author)

  18. Room 209 excavation response test in the underground research laboratory

    International Nuclear Information System (INIS)

    Lang, P.A.

    1989-01-01

    An in situ excavation response test was conducted at the Canadian Underground Research Laboratory (URL) in conjunction with excavation of a tunnel (Room 209) through a near-vertical water-bearing fracture oriented perpendicular to the tunnel axis. Encountering a fracture with such desirable characteristics provided a unique opportunity during construction of the URL to try out instrumentation and analytical methods for use in the Excavation Response Experiment (ERE) planned as one of the major URL experiments. The test has produced a valuable data set for validating numerical models. Four modelling groups predicted the response that would be monitored by the instruments. The predictions of the mechanical response were generally good. However, the predictions of the permeability and hydraulic pressure changes in the fracture, and the water flows into the tunnel, were poor. It is concluded that we may not understand the mechanisms that occur in the fracture in response to excavation. Laboratory testing, and development of a contracting joint code, has been initiated to further investigate this phenomenon. Preliminary results indicate that the excavation damaged zone in the walls and crown is less than 0.5 m thick and has relatively low permeability. The damaged zone in the floor is at least 1 m thick and has relatively high permeability. The damage in the floor could be reduced in future excavations by using controlled blasting methods similar to those used for the walls and crown

  19. Physical Research Laboratory radiocarbon 14C dates : CS-I

    International Nuclear Information System (INIS)

    Agrawal, D.P.; Krishnamurthy, R.V.; Kusumgar, Sheela; Pant, R.K.

    1978-01-01

    The 14 C dates of archaeological samples measured at the Radiocarbon Laboratory of the Physical Research Laboratory, Ahmedabad are presented. Samples were converted into methane and measured in gas proportional counters. Ninety-five percent activity of NBS oxalic acid was used as modern standard. The dates in years B.P. are given for each sample based on the half-life values of 5568 +- 30 years and 5730 +- 40 years, the latter within parenthesis. The dates are not calibrated for 14 C/ 12 C variations. To convert the dates into AD/BC scale, 1950 AD should be used as reference year. A number of 14 C dates (PRL-81, -83, -67, -68) now confirm that the Painted Grey Ware culture extended upto the 3rd century BC. Some of the dates from Barkhera (PRL-113), Bateshwar (PRL-200), Bhimbetka (PRL-17) and Koldihawa (PRL-100, 101) are older than normally expected, probably indicative of some hitherto unknown basal cultures in these regions. 14 C dates on in situ Megalithic materials do not seem to go beyond 200 BC. (author)

  20. Studies and researches in the underground laboratory at Pasquasia mine

    International Nuclear Information System (INIS)

    Tassoni, E.; Cautilli, F.; Polizzano, C.; Zarlenga, F.

    1989-01-01

    The reliability of the geological disposal of radioactive wastes has to be verified both by laboratory and on site researches, under both surface and underground conditions. The tests carried out under high lithostatic stress can allow extrapolations to be made having absolute value at the depths planned for the construction of the repository. An underground laboratory was excavated at the Pasquasia mine (Enna-Sicilia). On the selected area a detailed geological survey (1:5000 scale) was carried out; for the purpose of studying the effects induced by the advancement of the excavation's face into the clayey mass and over the cross section of the transversal tunnel, several geotechnical measurement stations were installed. Structural observations were made on both the fronts and the walls of the tunnel for the purpose of characterizing the mechanical behaviour of the clayey mass. The 37 cubic blocks and the 72 samples collected during the excavation were analyzed from different point of view (sedimentological, mineralogical, geotechnical, etc.). After the excavation of the tunnel and the installation of the geotechnical stations, the measurements were carried out up to March 1987. At this date the work programme was unfortunately stopped by local authorities, unfoundly suspecting Pasquasia mine would be used as waste repository

  1. Idaho National Laboratory Directed Research and Development FY-2009

    Energy Technology Data Exchange (ETDEWEB)

    2010-03-01

    The FY 2009 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support the future DOE missions and national research priorities. LDRD is essential to the INL - it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enhances technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development. Established by Congress in 1991, LDRD proves its benefit each year through new programs, intellectual property, patents, copyrights, publications, national and international awards, and new hires from the universities and industry, which helps refresh the scientific and engineering workforce. The benefits of INL's LDRD research are many as shown in the tables below. Last year, 91 faculty members from various universities contributed to LDRD research, along with 7 post docs and 64 students. Of the total invention disclosures submitted in FY 2009, 7 are attributable to LDRD research. Sixty three refereed journal articles were accepted or published, and 93 invited presentations were attributable to LDRD research conducted in FY 2009. The LDRD Program is administered in accordance with requirements set in DOE Order 413.2B, accompanying contractor requirements, and other DOE and federal requirements invoked through the INL contract. The LDRD Program is implemented in accordance with the annual INL LDRD Program Plan, which is approved by the DOE, Nuclear Energy Program Secretarial Office. This plan outlines the method the laboratory uses to develop its research portfolio, including peer and management reviews, and the use of other INL management systems to ensure quality, financial, safety, security and environmental requirements and risks are

  2. Performance calculations for battery power supplies as laboratory research tools

    International Nuclear Information System (INIS)

    Scanlon, J.J.; Rolader, G.E.; Jamison, K.A.; Petresky, H.

    1991-01-01

    Electromagnetic Launcher (EML) research at the Air Force Armament Laboratory, Hypervelocity Launcher Branch (AFATL/SAH), Eglin AFB, has focused on developing the technologies required for repetitively launching several kilogram payloads to high velocities. Previous AFATL/SAH experiments have been limited by the available power supply resulting in small muzzle energies on the order of 100's of kJ. In an effort to advance the development of EML's, AFATL/SAH has designed and constructed a battery power supply (BPS) capable of providing several mega-Amperes of current for several seconds. This system consists of six modules each containing 2288 automotive batteries which may be connected in two different series - parallel arrangements. In this paper the authors define the electrical characteristics of the AFATL Battery Power supply at the component level

  3. Research opportunities in a reactor-based nuclear analytical laboratory

    International Nuclear Information System (INIS)

    Robinson, L.; Brown, D.H.

    1994-01-01

    Although considered by many to be a open-quotes matureclose quotes science, neutron activation analysis (NAA) continues to be a valuable elemental analysis tool. Examples of the applicability of NAA can be found in a variety of areas including archaeology, environmental science, epidemiology, forensic science, and materials science to name a few. The major components of neutron activation are sample preparation, irradiation, counting, and data analysis. Each one of these stages provides opportunities to share numerous practical and fundamental scientific principles with high school teachers. This paper presents an overview of these opportunities. In addition, a specific example of the collaboration with a high school teacher whose research involved the automation of a gamma-ray spectroscopy counting system using a laboratory robot is discussed

  4. Laboratory research at the clinical trials of Veterinary medicinal Products

    OpenAIRE

    ZHYLA M.I.

    2011-01-01

    The article analyses the importance of laboratory test methods, namely pathomorfological at conduct of clinical trials. The article focuses on complex laboratory diagnostics at determination of clinical condition of animals, safety and efficacy of tested medicinal product.

  5. Privacy Policy | Frederick National Laboratory for Cancer Research

    Science.gov (United States)

    The privacy of our users is of utmost importance to Frederick National Laboratory. The policy outlined below establishes how Frederick National Laboratory will use the information we gather about you from your visit to our website. We may coll

  6. The Laboratory Notebook as a Research and Development Record

    Science.gov (United States)

    Bailey, Martha J.

    1972-01-01

    The literature concerning laboratory notebooks is reviewed. A procedure is described for administering laboratory notebooks. Outlined is an indexing system which provides a method for retrieving information by laboratory notebook number, by name, and by general subjects. The indexing scheme is estimated to be adequate for collections up to 5,000…

  7. An Account of Oak Ridge National Laboratory's Thirteen Research Reactors

    International Nuclear Information System (INIS)

    Rosenthal, Murray Wilford

    2009-01-01

    The Oak Ridge National Laboratory has built and operated 13 nuclear reactors in its 66-year history. The first was the graphite reactor, the world's first operational nuclear reactor, which served as a plutonium production pilot plant during World War II. It was followed by two aqueous-homogeneous reactors and two red-hot molten-salt reactors that were parts of power-reactor development programs and by eight others designed for research and radioisotope production. One of the eight was an all-metal fast burst reactor used for health physics studies. All of the others were light-water cooled and moderated, including the famous swimming-pool reactor that was copied dozens of times around the world. Two of the reactors were hoisted 200 feet into the air to study the shielding needs of proposed nuclear-powered aircraft. The final reactor, and the only one still operating today, is the High Flux Isotope Reactor (HFIR) that was built particularly for the production of californium and other heavy elements. With the world's highest flux and recent upgrades that include the addition of a cold neutron source, the 44-year-old HFIR continues to be a valuable tool for research and isotope production, attracting some 500 scientific visitors and guests to Oak Ridge each year. This report describes all of the reactors and their histories.

  8. Monitoring and information management system at the Underground Research Laboratory

    International Nuclear Information System (INIS)

    Strobel, G.S.; Chernis, P.J.; Bushman, A.T.; Spinney, M.H.; Backer, R.J.

    1996-01-01

    Atomic Energy of Canada Limited (AECL) has developed a customer oriented monitoring and information management system at the Underground Research Laboratory (URL) near Lac du Bonnet, Manitoba. The system is used to monitor instruments and manage, process, and distribute data. It consists of signal conditioners and remote loggers, central schedule and control systems, computer aided design and drafting work centres, and the communications linking them. The monitoring and communications elements are designed to meet the harsh demands of underground conditions while providing accurate monitoring of sensitive instruments to rigorous quality assured specifications. These instruments are used for testing of the concept for the deep geological disposal of nuclear fuel waste as part of the Canadian Nuclear Fuel Waste Management Program. Many of the tests are done in situ and at full-scale. The monitoring and information management system services engineering, research, and support staff working to design, develop, and demonstrate and present the concept. Experience gained during development of the monitoring and information management system at the URL, can be directly applied at the final disposal site. (author)

  9. Monitoring and information management system at the Underground Research Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Strobel, G.S.; Chernis, P.J.; Bushman, A.T.; Spinney, M.H.; Backer, R.J. [Atomic Energy of Canada Limited, Pinawa, Manitoba (Canada)

    1996-07-01

    Atomic Energy of Canada Limited (AECL) has developed a customer oriented monitoring and information management system at the Underground Research Laboratory (URL) near Lac du Bonnet, Manitoba. The system is used to monitor instruments and manage, process, and distribute data. It consists of signal conditioners and remote loggers, central schedule and control systems, computer aided design and drafting work centres, and the communications linking them. The monitoring and communications elements are designed to meet the harsh demands of underground conditions while providing accurate monitoring of sensitive instruments to rigorous quality assured specifications. These instruments are used for testing of the concept for the deep geological disposal of nuclear fuel waste as part of the Canadian Nuclear Fuel Waste Management Program. Many of the tests are done in situ and at full-scale. The monitoring and information management system services engineering, research, and support staff working to design, develop, and demonstrate and present the concept. Experience gained during development of the monitoring and information management system at the URL, can be directly applied at the final disposal site. (author)

  10. Environmental survey at Lucas Heights Research Laboratories, 1992

    International Nuclear Information System (INIS)

    Hoffman, E.L.; Loosz, T.

    1994-07-01

    This report summarises the results from the environmental survey during 1992 and assesses the effects of radioactive discharges on both local population and the environment. None of the samples taken from possible human food chains in the vicinity of the Lucas Heights Research Laboratories contained radioactivity which could be attributed to the operation of the site. The data presented din this report clearly shows that the environmental impact of operations at LHRL has been very low. The effective dose to residents living in the immediate neighbourhood of the reactor are very difficult to measure directly but calculated dose estimates are far lower than those due to natural background radiation and medical exposures. Discharges of airborne radioactive gases were within authorised limits when averaged over the year. The dose to the most sensitive members of the public from iodine-131 releases, was -2 mSv/year and the calculated dose from released noble gases to the most exposed individuals was less than 0.01 mSv/year. These figures represent less than one per cent of the limits recommended by the National Health and Medical Research Council of Australia. The monthly average liquid effluent discharge to the Water Board Sewer during 1992 was less than 30 per cent of the permitted level for all periods except May which rose to 62 per cent. For tritium, the concentration was less than 2 per cent of the specified limit. 23 refs., 19 tabs., 5 tabs

  11. Brookhaven National Laboratory's Accelerator Test Facility: research highlights and plans

    Science.gov (United States)

    Pogorelsky, I. V.; Ben-Zvi, I.

    2014-08-01

    The Accelerator Test Facility (ATF) at Brookhaven National Laboratory has served as a user facility for accelerator science for over a quarter of a century. In fulfilling this mission, the ATF offers the unique combination of a high-brightness 80 MeV electron beam that is synchronized to a 1 TW picosecond CO2 laser. We unveil herein our plan to considerably expand the ATF's floor space with an upgrade of the electron beam's energy to 300 MeV and the CO2 laser's peak power to 100 TW. This upgrade will propel the ATF even further to the forefront of research on advanced accelerators and radiation sources, supporting the most innovative ideas in this field. We discuss emerging opportunities for scientific breakthroughs, including the following: plasma wakefield acceleration studies in research directions already active at the ATF; laser wakefield acceleration (LWFA), where the longer laser wavelengths are expected to engender a proportional increase in the beam's charge while our linac will assure, for the first time, the opportunity to undertake detailed studies of seeding and staging of the LWFA; proton acceleration to the 100-200 MeV level, which is essential for medical applications; and others.

  12. Decommissioning program and future plan for research hot laboratory (2)

    International Nuclear Information System (INIS)

    Koya, Toshio; Nozawa, Yukio; Hanada, Yasushi; Ono, Katsuto; Kanazawa, Hiroyuki; Nihei, Yasuo; Owada, Isao

    2010-01-01

    The Research Hot Laboratory (RHL) in Japan Atomic Energy Agency (JAEA) was constructed in 1961, as the first one in JAPAN, to perform the examinations of irradiated fuels and materials. RHL consists of 10 heavy concrete cells and 38 lead cells, which had been contributed to research and development program in or out of JAEA for the investigation of irradiation behavior for fuels and nuclear materials. However, RHL is the one of target as the rationalization program for decrepit facilities in former Tokai institute. Therefore the decommissioning works of RHL have been started on April 2003. The decommissioning work will be progressing, dismantling the lead cells and decontamination of concrete caves then release in the regulation of controlled area. The 18 lead cells (including semi-hot cell and junior-cell) had been dismantled. Removal of the applause from the cells, survey of the contamination revel in the lead cells and prediction of radio active waste have been finished as the preparing work for dismantling of the remained 20 lead cells. The future plan of decommissioning work has been prepared to incarnate the basic vision and dismantling procedure. (author)

  13. Enabling laboratory EUV research with a compact exposure tool

    Science.gov (United States)

    Brose, Sascha; Danylyuk, Serhiy; Tempeler, Jenny; Kim, Hyun-su; Loosen, Peter; Juschkin, Larissa

    2016-03-01

    In this work we present the capabilities of the designed and realized extreme ultraviolet laboratory exposure tool (EUVLET) which has been developed at the RWTH-Aachen, Chair for the Technology of Optical Systems (TOS), in cooperation with the Fraunhofer Institute for Laser Technology (ILT) and Bruker ASC GmbH. Main purpose of this laboratory setup is the direct application in research facilities and companies with small batch production, where the fabrication of high resolution periodic arrays over large areas is required. The setup can also be utilized for resist characterization and evaluation of its pre- and post-exposure processing. The tool utilizes a partially coherent discharge produced plasma (DPP) source and minimizes the number of other critical components to a transmission grating, the photoresist coated wafer and the positioning system for wafer and grating and utilizes the Talbot lithography approach. To identify the limits of this approach first each component is analyzed and optimized separately and relations between these components are identified. The EUV source has been optimized to achieve the best values for spatial and temporal coherence. Phase-shifting and amplitude transmission gratings have been fabricated and exposed. Several commercially available electron beam resists and one EUV resist have been characterized by open frame exposures to determine their contrast under EUV radiation. Cold development procedure has been performed to further increase the resist contrast. By analyzing the exposure results it can be demonstrated that only a 1:1 copy of the mask structure can be fully resolved by the utilization of amplitude masks. The utilized phase-shift masks offer higher 1st order diffraction efficiency and allow a demagnification of the mask structure in the achromatic Talbot plane.

  14. Conceptual Design, Engineering Modeling, and Experimental Validation of Air Sampling System for Chemical Sensor Insertion into the U.S. Army Research Laboratory's (ARL) Silent Operating Aerial Reconnaissance (SOAR) Program

    National Research Council Canada - National Science Library

    Nair, Michael

    2004-01-01

    ...) as a chemical weapons detection platform. This report details a preliminary effort to determine whether the UAV is capable of sustaining the needed air flow into a chemical weapons detector to ensure functionality...

  15. National Research Council Research Associateships Program with Methane Hydrates Fellowships Program/National Energy Technology Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Basques, Eric O. [National Academy of Sciences, Washington, DC (United States)

    2014-03-20

    This report summarizes work carried out over the period from July 5, 2005-January 31, 2014. The work was carried out by the National Research Council Research Associateships Program of the National Academies, under the US Department of Energy's National Energy Technology Laboratory (NETL) program. This Technical Report consists of a description of activity from 2005 through 2014, broken out within yearly timeframes, for NRC/NETL Associateships researchers at NETL laboratories which includes individual tenure reports from Associates over this time period. The report also includes individual tenure reports from associates over this time period. The report also includes descriptions of program promotion efforts, a breakdown of the review competitions, awards offered, and Associate's activities during their tenure.

  16. Customizable Electronic Laboratory Online (CELO): A Web-based Data Management System Builder for Biomedical Research Laboratories

    Science.gov (United States)

    Fong, Christine; Brinkley, James F.

    2006-01-01

    A common challenge among today’s biomedical research labs is managing growing amounts of research data. In order to reduce the time and resource costs of building data management tools, we designed the Customizable Electronic Laboratory Online (CELO) system. CELO automatically creates a generic database and web interface for laboratories that submit a simple web registration form. Laboratories can then use a collection of predefined XML templates to assist with the design of a database schema. Users can immediately utilize the web-based system to query data, manage multimedia files, and securely share data remotely over the internet. PMID:17238541

  17. The hot cell laboratories for material investigations of the Institute for Safety Research

    Energy Technology Data Exchange (ETDEWEB)

    Viehrig, H W

    1998-10-01

    Special facilities for handling and testing of irradiated specimens are necessary, to perform the investigation of activated material. The Institute for Safety Research has two hot cell laboratories: - the preparation laboratory and - the materials testing laboratory. This report is intended to give an overview of the available facilities and developed techniques in the laboratories. (orig.)

  18. Progress report for (1974-1984) of Nuclear Research Laboratory, Srinagar, Kashmir

    International Nuclear Information System (INIS)

    Kaul, P.K.; Razdan, H.

    1985-01-01

    The Nuclear Research Laboratory, established at Srinagar in 1974, serves as a base laboratory to organise research activities at the High Altitude Research Laboratory at Gulmarg. Space physics, nuclear physics, radiation and atmospheric chemistry, and technical physics: are the fields in which the research facilities are established at the Laboratory, over the past ten years. The highlights of the various research programmes undertaken at the Laboratory during the period 1974-1984 are presented in the form of summaries. A list of papers published in various journals and presented at different conferences, symposia etc. is given at the end. (M.G.B.)

  19. Environmental survey at Lucas Heights Research Laboratories, 1991

    International Nuclear Information System (INIS)

    Hoffmann, E.L.; Looz, T.

    1994-05-01

    In common with many other nuclear facilities, ANSTO undertakes an extensive program of meteorological measurements. The prime reason for such a program is to allow estimates to be made of the downwind concentration of any airborne pollutants, particularly radionuclides, released from the site through routine operations or under accident conditions. The data collection from this program provide the necessary input to the atmospheric dispersion model called ADDCOR (ANSTO 1989) which can be used to compute the effective dose to an individual due to the routine airborne or accidental release of radionuclides from the LHRL. None of the samples taken from possible human food chains in the vicinity of the Lucas Heights Research Laboratories contained radioactivity which could be attributed to the operation of the site. Discharges of airborne radioactive gases were within authorised limits when averaged over the year. The dose to the most sensitive members of the public from iodine-131 release, was -3 mSv/year and the calculated dose from released noble gases to the most exposed individuals was less than 0.01 mSv/year. These figures represent less than one per cent of the most restrictive limits recommended by the National Health and Medical Research Council of Australia. The annual average liquid effluent discharge to the Water Board Sewer during 1991 was less than 29 per cent of the permitted level. For tritium, the concentration was less than 2 per cent of the specified limit. The data presented in this report clearly shows that the environmental impact of operations at LHRL has been very low. The effective dose to residents living in the immediate neighbourhood of the reactor are very difficult to measure directly but calculated dose estimates are far lower than those due to natural background radiation and medical exposures. 24 refs., 19 tabs., 4 figs

  20. Configuration of the Virtual Laboratory for Fusion Researches in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, T.; Nagayama, Y.; Nakanishi, H.; Ishiguro, S.; Takami, S.; Tsuda, K.; Okamura, S. [National Institute for Fusion Science, National Institutes of Natural Sciences, Toki (Japan)

    2009-07-01

    SNET is a virtual laboratory system for nuclear fusion research in Japan, it has been developed since 2001 with SINET3, which is a national academic network backbone operated by National Institute of Computer sciences. Twenty one sites including major Japanese universities, JAEA and NIFS are mutually connected on SNET with the speed of 1 Gbps in 2008 fiscal year. The SNET is a closed network system based on L2 and L3 VPN and is connected to the web through the firewall at NIFS for security maintenance. Collaboration categories in SNET are as follows: the LHD remote participation; the remote use of supercomputer system; the all Japan ST (Spherical Tokamak) research program. For example, the collaborators of the first category in a remote station can control their diagnostic devices at LHD and analyze the LHD data as if they were at the LHD control room. The detail of the network policy is different from each other because each category has its own particular purpose. In October 2008, the Kyushu University and NIFS were connected by L2 VPN. The site was already connected by L3 VPN, but the data transfer rate was rather low. L2 VPN supports the bulk data transfer which is produced by QUEST, the spherical tokamak device at Kyushu University. The wide-area broadcast test began to distribute to remote stations the video which is presented at the front panel of the LHD control room. ITER activity started in 2007 and 'The ITER Remote Experimentation Centre' will be constructed at the Rokkasho village in Japan under ITER-BA agreement. SNET would be useful for distributing the data of ITER to Japanese universities and institutions. (authors)

  1. Descriptive Summaries of the Research, Development, Test and Evaluation, Army Appropriation. Supporting Data FY 1994, Budget Estimates Submitted to Congress, April 1993

    Science.gov (United States)

    1993-04-01

    Investigate the genetics and physiology of Yersinia pestis, Brucella Sp., Q-fever, Vibrio cholerae , Francisella tularensis and Bacillus anthracis "* (U) Conduct...New Mexico State University, NM; Optimetrics, Inc., Ann Arbor, MI; Massachusetts Institute of Technology. Cambridge, MA; Mission Research Corporation...Laboratory (ARL), Adelphi, MD. Contractors include: New Mexico Institute of Mining and Technology, Socorro, NM; Dynamic Sciences, Inc., Phoenix, AZ; Honeywell

  2. Frederick National Laboratory's Contribution to ATOM | Frederick National Laboratory for Cancer Research

    Science.gov (United States)

    As a founding member organization of ATOM, the Frederick National Laboratory will contribute scientific expertise in precision oncology, computational chemistry and cancer biology, as well as support for open sharing of data sets and predictive model

  3. DISMANTLING OF THE FUEL CELL LABORATORY AT RESEARCH CENTRE JUELICH

    International Nuclear Information System (INIS)

    Stahn, B.; Matela, K.; Bensch, D.; Ambos, Frank

    2003-01-01

    The fuel cell laboratory was constructed in three phases and taken into operation in the years 1962 to 1966. The last experimental work was carried out in 1996. After all cell internals had been disassembled, the fuel cell laboratory was transferred to shutdown operation in 1997. Three cell complexes, which differed, in particular, by the type of shielding (lead, cast steel, concrete), were available until then for activities at nuclear components. After approval by the regulatory authority, the actual dismantling of the fuel cell laboratory started in March 2000. The BZ I laboratory area consisted of 7 cells with lead shieldings of 100 to 250 mm thickness. This area was dismantled from April to September 2000. Among other things, approx. 30,000 lead bricks with a total weight of approx. 300 Mg were dismantled and disposed of. The BZ III laboratory area essentially consisted of cells with concrete shieldings of 1200 to 1400 mm thickness. The dismantling of this area started in the fir st half of 2001 and was completed in November 2002. Among other things, approx. 900 Mg of concrete was dismantled and disposed of. Since more than 90 % of the dismantled materials was measurable for clearance, various clearance measurement devices were used during dismantling. The BZ II laboratory area essentially consists of cells with cast steel shieldings of 400 to 460 mm thickness. In September 2002 it was decided to continue using this laboratory area for future tasks. The dismantling of the fuel cell laboratory was thus completed. After appropriate refurbishment, the fuel cell laboratory will probably take up operation again in late 2003

  4. RF Anechoic Chambers, Tri-Service Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — In collaboration with the Navy, there are 12 RF Anechoic and static free exposure chambers located at TSRL. These chambers cover the majority of the RF spectrum and...

  5. POLLUTION PREVENTION RESEARCH ONGOING - EPA'S RISK REDUCTION ENGINEERING LABORATORY

    Science.gov (United States)

    The mission of the Risk Reduction Engineering Laboratory is to advance the understanding, development and application of engineering solutions for the prevention or reduction of risks from environmental contamination. This mission is accomplished through basic and applied researc...

  6. Large-Scale Laboratory Facility For Sediment Transport Research

    Data.gov (United States)

    Federal Laboratory Consortium — Effective design and maintenance of inlet navigation and shore protection projects require accurate estimates of the quantity of sand that moves along the beach. The...

  7. Chemistry and materials science progress report. Weapons-supporting research and laboratory directed research and development: FY 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    This report covers different materials and chemistry research projects carried out a Lawrence Livermore National Laboratory during 1995 in support of nuclear weapons programs and other programs. There are 16 papers supporting weapons research and 12 papers supporting laboratory directed research.

  8. Chemistry and materials science progress report. Weapons-supporting research and laboratory directed research and development: FY 1995

    International Nuclear Information System (INIS)

    1996-04-01

    This report covers different materials and chemistry research projects carried out a Lawrence Livermore National Laboratory during 1995 in support of nuclear weapons programs and other programs. There are 16 papers supporting weapons research and 12 papers supporting laboratory directed research

  9. Signal and Image Processing Research at the Lawrence Livermore National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, R S; Poyneer, L A; Kegelmeyer, L M; Carrano, C J; Chambers, D H; Candy, J V

    2009-06-29

    Lawrence Livermore National Laboratory is a large, multidisciplinary institution that conducts fundamental and applied research in the physical sciences. Research programs at the Laboratory run the gamut from theoretical investigations, to modeling and simulation, to validation through experiment. Over the years, the Laboratory has developed a substantial research component in the areas of signal and image processing to support these activities. This paper surveys some of the current research in signal and image processing at the Laboratory. Of necessity, the paper does not delve deeply into any one research area, but an extensive citation list is provided for further study of the topics presented.

  10. Laboratory Directed Research and Development Program FY2016 Annual Summary of Completed Projects

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2017-03-30

    ORNL FY 2016 Annual Summary of Laboratory Directed Research and Development Program (LDRD) Completed Projects. The Laboratory Directed Research and Development (LDRD) program at ORNL operates under the authority of DOE Order 413.2C, “Laboratory Directed Research and Development” (October 22, 2015), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. The LDRD program funds are obtained through a charge to all Laboratory programs. ORNL reports its status to DOE in March of each year.

  11. miR-214 down-regulates ARL2 and suppresses growth and invasion of cervical cancer cells

    International Nuclear Information System (INIS)

    Peng, Ruiqing; Men, Jianlong; Ma, Rui; Wang, Qian; Wang, Yang; Sun, Ying; Ren, Jing

    2017-01-01

    Increasing evidence has shown that miRNAs are implicated in carcinogenesis and can function as oncogenes or tumor suppressor genes in human cancers. In this study, we confirmed that miR-214 is frequently down-regulated in cervical cancer compared with normal cervical tissues. Ectopic expression of miR-214 suppressed proliferation, migration and invasion of HeLa and C33A cervical cancer cells. Bioinformatics analysis revealed that ADP ribosylation factor like 2 (ARL2) was a potential target of miR-214 and was remarkably up-regulated in cervical cancer. Knockdown of ARL2 markedly inhibited cervical cancer cell proliferation, migration and invasion, similarly to over-expression of miR-214, indicating that ARL2 may function as an oncogene in cervical cancer. In conclusion, our study revealed that miR-214 acts as a tumor suppressor via inhibiting proliferation, migration and invasion of cervical cancer cells through targeting ARL2, and that both miR-214 and ARL2 may serve as prognostic or therapeutic targets for cervical cancer. - Highlights: • miR-214 targets ARL2. • ARL2 maybe an oncogene in cervical cancer. • ARL2 rescues miR-214.

  12. Laboratory Directed Research and Development Annual Report - Fiscal Year 2000

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, Darrell R.; Hughes, Pamela J.; Pearson, Erik W.

    2001-04-01

    The projects described in this report represent the Laboratory's investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. In accordance with DOE guidelines, the report provides, a) a director's statement, b) an overview of the laboratory's LDRD program, including PNNL's management process and a self-assessment of the program, c) a five-year project funding table, and d) project summaries for each LDRD project.

  13. A Place for Materials Science: Laboratory Buildings and Interdisciplinary Research at the University of Pennsylvania

    Science.gov (United States)

    Choi, Hyungsub; Shields, Brit

    2015-01-01

    The Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, was built in 1965 as part of the Advanced Research Projects Agency's (ARPA) Interdisciplinary Laboratories (IDL) program intended to foster interdisciplinary research and training in materials science. The process that led to the construction of the…

  14. From Cookbook to Research: Redesigning an Advanced Biochemistry Laboratory

    Science.gov (United States)

    Boyd-Kimball, Debra; Miller, Keith R.

    2018-01-01

    Laboratory courses are often designed using step-by-step protocols which encourage students to conduct experiments without thinking about what they are doing or why they are doing it. Such course design limits the growth of our students as scientists and can make it more difficult for a student to transition to the expectations of a research…

  15. Measurement Instruments and Software Used in Biotribology Research Laboratory

    Directory of Open Access Journals (Sweden)

    Tyurin Andrei

    2015-07-01

    Full Text Available Precision measurements of friction processes have a key role in a variety of industrial processes. The emergence of fine electronic circuit techniques greatly expands capabilities of control. There are some difficulties for their full implementation today, especially when it regards the accuracy and frequency of measurements. The motion-measuring method in real-time system is considered in this article, paying special attention to increased accuracy. This method is based on rapid analog digital converter (ADC, transmission program and digital signal processor (DSP algorithms. Description of laboratory devices is included: Tribal-T and universal friction machine (MTU-01 designed for “Pin on disc” tests. Great emphasis is placed on the usability of accelerometers. The present study examined the collected data via laboratory system for data acquisition and control, and processing it in the laboratory of Biotribology. Laboratory supervisory control and data acquisition (SCADA algorithms is described below. Task of regulation is not considered. This paper describes only methods of automatic control theory to analyze the frictional quality.

  16. Research Laboratory of Electronics Progress Report Number 133

    Science.gov (United States)

    1991-08-01

    The substantial labora- ZnSe tory renovation was completed in February; the CBE system hardware was delivered in March and Sponsors installed...laboratories of E.N.E.A. ( Energia ceedings of the International Sherwood Theory Nucleare e Energie Alternative), as well as in- Meeting, Williamsburg, Virginia

  17. Laboratory Directed Research and Development FY2010 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, K J

    2011-03-22

    A premier applied-science laboratory, Lawrence Livermore National Laboratory (LLNL) has at its core a primary national security mission - to ensure the safety, security, and reliability of the nation's nuclear weapons stockpile without nuclear testing, and to prevent and counter the spread and use of weapons of mass destruction: nuclear, chemical, and biological. The Laboratory uses the scientific and engineering expertise and facilities developed for its primary mission to pursue advanced technologies to meet other important national security needs - homeland defense, military operations, and missile defense, for example - that evolve in response to emerging threats. For broader national needs, LLNL executes programs in energy security, climate change and long-term energy needs, environmental assessment and management, bioscience and technology to improve human health, and for breakthroughs in fundamental science and technology. With this multidisciplinary expertise, the Laboratory serves as a science and technology resource to the U.S. government and as a partner with industry and academia. This annual report discusses the following topics: (1) Advanced Sensors and Instrumentation; (2) Biological Sciences; (3) Chemistry; (4) Earth and Space Sciences; (5) Energy Supply and Use; (6) Engineering and Manufacturing Processes; (7) Materials Science and Technology; Mathematics and Computing Science; (8) Nuclear Science and Engineering; and (9) Physics.

  18. Air Force Research Laboratory Success Stories : A Review of 2004

    Science.gov (United States)

    2004-01-01

    Phase IV performed a waveform characterization of the entire radar system. U Gain in the Electrico i Laboratory System Work sponsored by the AFRL...permanent disability, or death in recreational and professional activities that incorporate speed and agility, like auto racing, motorcycling, and skiing

  19. Web Usability Policies/Standards/Guidelines Do Not Influence Practices at ARL Academic Libraries. A Review of: Chen, Yu‐Hui, Carol Anne Germain and Huahai Yang. “An Exploration into the Practices of Library Web Usability in ARL Academic Libraries.” Journal of the American Society for Information Science and Technology 60.5 (2009: 953‐68.

    Directory of Open Access Journals (Sweden)

    Shandra Protzko

    2009-12-01

    Full Text Available Objective – To survey the current status of Web usability Policies/Standards/Guidelines (PSGs found in academic libraries of the Association of Research Libraries (ARL. Researchers sought to investigate whether PSGs are in place, the levels of difficulty surrounding implementation, the impact of PSGs on design, testing, and resource allocation, and the relationship between ARL ranking and usability practice or PSGs.Design – Survey.Setting – North America.Subjects – Academic libraries of the ARL.Methods – An 18‐question survey consisting of multiple choice, Likert scale, and open‐ended questions was sent to all 113 ARL libraries in November 2007. Survey recipients were selected as the person in charge of Web site usability by visiting library Web sites and phone inquiry. The survey was concluded in January 2008 with a response rate of 74% (84 institutions. The researchers used t‐test to detect any difference in ARL library ranking between libraries with and without PSGs. Pair‐wise t‐tests were conducted to identify gaps in difficulty implementing PSGs. In addition, they used Pearson’s Correlation to investigate any significant correlations between variables such as ARL rank and resource allocation.Main Results – Of the 84 respondents, 34 (40% have general library Web PSGs and 25 (30% have specific usability PSGs; 41 (49% have at least one type of in‐library PSG. Of the 43 (51% libraries that do not have PSGs, 30 (36% are at universities with institutional Web usability PSGs; 26 (87% follow those guidelines. There was no statistically significant relationship between ARL ranking and PSG status (see Table 1. The authors asked about difficulty in implementing PSGs. Of the 32 libraries responding to a question about general library Web PSGs, most had slight or moderate difficulty. Twenty‐three libraries with specific usability PSGs identified difficulty levels; some had no difficulty, but a majority had moderate difficulty

  20. Perspective on One Decade of Laser Propulsion Research at the Air Force Research Laboratory, November 1995-2005 (DVD)

    National Research Council Canada - National Science Library

    2007-01-01

    .... PHYSICAL DESCRIPTION: 1 DVD-ROM and 1 CD-ROM; 4 3/4 in.; 395 MB. ABSTRACT: A short film and presentation on laser propulsion research at the Air Force Research Laboratory, spanning November 1995 through October 2005...

  1. Open- and closed-formula laboratory animal diets and their importance to research.

    Science.gov (United States)

    Barnard, Dennis E; Lewis, Sherry M; Teter, Beverly B; Thigpen, Julius E

    2009-11-01

    Almost 40 y ago the scientific community was taking actions to control environmental factors that contribute to variation in the responses of laboratory animals to scientific manipulation. Laboratory animal diet was recognized as an important variable. During the 1970s, the American Institute of Nutrition, National Academy of Science, Institute of Laboratory Animal Resources, and Laboratory Animals Centre Diets Advisory Committee supported the use of 'standard reference diets' in biomedical research as a means to improve the ability to replicate research. As a result the AIN76 purified diet was formulated. During this same time, the laboratory animal nutritionist at the NIH was formulating open-formula, natural-ingredient diets to meet the need for standardized laboratory animal diets. Since the development of open-formula diets, fixed-formula and constant-nutrient-concentration closed-formula laboratory animal natural ingredient diets have been introduced to help reduce the potential variation diet can cause in research.

  2. Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories.

    Science.gov (United States)

    Homer, Lesley C; Alderman, T Scott; Blair, Heather Ann; Brocard, Anne-Sophie; Broussard, Elaine E; Ellis, Robert P; Frerotte, Jay; Low, Eleanor W; McCarthy, Travis R; McCormick, Jessica M; Newton, JeT'Aime M; Rogers, Francine C; Schlimgen, Ryan; Stabenow, Jennifer M; Stedman, Diann; Warfield, Cheryl; Ntiforo, Corrie A; Whetstone, Carol T; Zimmerman, Domenica; Barkley, Emmett

    2013-03-01

    The Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories were developed by biosafety professionals who oversee training programs for the 2 national biocontainment laboratories (NBLs) and the 13 regional biocontainment laboratories (RBLs) that participate in the National Institute of Allergy and Infectious Diseases (NIAID) NBL/RBL Network. These guidelines provide a general training framework for biosafety level 3 (BSL-3) high-containment laboratories, identify key training concepts, and outline training methodologies designed to standardize base knowledge, understanding, and technical competence of laboratory personnel working in high-containment laboratories. Emphasis is placed on building a culture of risk assessment-based safety through competency training designed to enhance understanding and recognition of potential biological hazards as well as methods for controlling these hazards. These guidelines may be of value to other institutions and academic research laboratories that are developing biosafety training programs for BSL-3 research.

  3. The Medical Activation Analysis Research Programme of the IAEA Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Parr, R. M. [Medical Applications Section, International Atomic Energy Agency, Vienna (Austria)

    1970-07-01

    Analyses carried out under the Agency's laboratory programme in medical activation analysis commended in 1967. This paper describes the laboratory facilities and experimental methods now in use, and reports briefly on results obtained to date. The analytical scheme places greatest emphasis on non-destructive methods (i.e. without radiochemistry), and by the use of a Ge(Li) detector and a 2-parameter Nal(Tl) gamma-ray spectrometer, presently allows the determination of up to 12 elements in unprocessed tissue samples. Projects completed or underway include (i) an investigation into the uniformity of distribution of mineral elements in human liver, (ii) studies of tissue concentrations of trace elements in relation to malnutrition and cardiovascular diseases, and (iii) the determination of iodine in food, natural waters and other biological materials in relation to the epidemiology of endemic goitre. (author)

  4. Report of the research results with University of Tokyo Nuclear Engineering Research Laboratory's facilities in fiscal 1975

    International Nuclear Information System (INIS)

    1976-08-01

    Results of the research works by educational institutions using fast neutron source reactor 'Yayoi' etc. of Nuclear Engineering Research Laboratory in fiscal 1975 are reported in individual summaries. Fields of research are the following: shielding benchmark experiment, research on medical irradiation, irradiation experiments, experiments by small research groups, fast neutron streaming experiment, and so on. (Mori, K.)

  5. Laboratory Directed Research and Development Annual Report for 2009

    International Nuclear Information System (INIS)

    Hughes, Pamela J.

    2010-01-01

    This report documents progress made on all LDRD-funded projects during fiscal year 2009. As a US Department of Energy (DOE) Office of Science (SC) national laboratory, Pacific Northwest National Laboratory (PNNL) has an enduring mission to bring molecular and environmental sciences and engineering strengths to bear on DOE missions and national needs. Their vision is to be recognized worldwide and valued nationally for leadership in accelerating the discovery and deployment of solutions to challenges in energy, national security, and the environment. To achieve this mission and vision, they provide distinctive, world-leading science and technology in: (1) the design and scalable synthesis of materials and chemicals; (2) climate change science and emissions management; (3) efficient and secure electricity management from generation to end use; and (4) signature discovery and exploitation for threat detection and reduction. PNNL leadership also extends to operating EMSL: the Environmental Molecular Sciences Laboratory, a national scientific user facility dedicated to providing itnegrated experimental and computational resources for discovery and technological innovation in the environmental molecular sciences.

  6. Laboratory Directed Research and Development Annual Report for 2009

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, Pamela J.

    2010-03-31

    This report documents progress made on all LDRD-funded projects during fiscal year 2009. As a US Department of Energy (DOE) Office of Science (SC) national laboratory, Pacific Northwest National Laboratory (PNNL) has an enduring mission to bring molecular and environmental sciences and engineering strengths to bear on DOE missions and national needs. Their vision is to be recognized worldwide and valued nationally for leadership in accelerating the discovery and deployment of solutions to challenges in energy, national security, and the environment. To achieve this mission and vision, they provide distinctive, world-leading science and technology in: (1) the design and scalable synthesis of materials and chemicals; (2) climate change science and emissions management; (3) efficient and secure electricity management from generation to end use; and (4) signature discovery and exploitation for threat detection and reduction. PNNL leadership also extends to operating EMSL: the Environmental Molecular Sciences Laboratory, a national scientific user facility dedicated to providing itnegrated experimental and computational resources for discovery and technological innovation in the environmental molecular sciences.

  7. The Studsvik Science Research Laboratory. Progress Report 1977

    International Nuclear Information System (INIS)

    1978-01-01

    The research activities during 1977 are reported. The research programme includes neutron physics, neutron absorption and scattering, radiation chemistry and photochemistry, radiation damage, radioactivity, and theory. (L.E.)

  8. Equipment qualification testing methodology research at Sandia Laboratories

    International Nuclear Information System (INIS)

    Jeppesen, D.

    1983-01-01

    The Equipment Qualification Research Testing (EQRT) program is an evolutionary outgrowth of the Qualification Testing Evaluation (QTE) program at Sandia. The primary emphasis of the program has been qualification methodology research. The EQRT program offers to the industry a research-oriented perspective on qualification-related component performance, as well as refinements to component testing standards which are based upon actual component testing research

  9. Use of Laboratory Animals in Biomedical and Behavioral Research.

    Science.gov (United States)

    Ministry of Education, Addis Ababa (Ethiopia).

    The use of animals in scientific research has been a controversial issue for over a hundred years. Research with animals has saved human lives, lessened human suffering, and advanced scientific understanding, yet that same research can cause pain and distress for the animals involved and may result in their death. It is hardly surprising that…

  10. seed storage proteins arl2 and its variants from the apa locus of wild ...

    African Journals Online (AJOL)

    sion of arcelin and ARL2 tepary bean proteins. Furthermore, a reduction in size and weight of emerged adult insects to almost half was observed. This work demonstrates the superior resistance common bean backcross lines to A. obtectus conferred by the presence of the APA proteins introgressed from tepary bean.

  11. Evaluation of Radiometers Deployed at the National Renewable Energy Laboratory's Solar Radiation Research Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Habte, Aron; Wilcox, Stephen; Stoffel, Thomas

    2015-12-23

    This study analyzes the performance of various commercially available radiometers used for measuring global horizontal irradiances and direct normal irradiances. These include pyranometers, pyrheliometers, rotating shadowband radiometers, and a pyranometer with fixed internal shading and are all deployed at the National Renewable Energy Laboratory's Solar Radiation Research Laboratory. Data from 32 global horizontal irradiance and 19 direct normal irradiance radiometers are presented. The radiometers in this study were deployed for one year (from April 1, 2011, through March 31, 2012) and compared to measurements from radiometers with the lowest values of estimated measurement uncertainties for producing reference global horizontal irradiances and direct normal irradiances.

  12. Annual report of Nuclear Engineering Research Laboratory, University of Tokyo in fiscal 1989

    International Nuclear Information System (INIS)

    1990-01-01

    This report summerizes the research and educational activities at the Nuclear Engineering Research Laboratory, Faculty of Engineering, University of Tokyo. The Laboratory holds four main facilities, which are Yayoi reactor, an electron accelerator, fusion blanket research facility, and heavy ion irradiation research facility. And they are open to the researchers both inside and outside the University. The application of the facilities are described. The activities and achievements of the Laboratory staffs, and theses for graduate, master, and doctor degrees are also summerized. (J.P.N.)

  13. Radiological safety considerations in the design and operation of the ORNL Transuranium Research Laboratory (TRL)

    International Nuclear Information System (INIS)

    Haynes, C.E.

    1976-01-01

    The Transuranium Research Laboratory (TRL) is the central facility at Oak Ridge National Laboratory (ORNL) for chemical and physical research involving transuranium elements. Transuranium Research Laboratory investigations are about equally divided between studies of inorganic and structural chemistry of the heavy elements and nuclear structure and properties of their isotopes. Elements studied include neptunium, plutonium, americium, curium, berkelium, californium, and einsteinium, each in microgram-to-gram quantities depending upon availability and experimental requirements. This paper describes an eight-step safety procedure followed in planning and approving individual research projects. This procedure should provide an optimum margin of safety and should permit the accomplishment of successful research

  14. Progress in inertial fusion research at Los Alamos Scientific Laboratory

    International Nuclear Information System (INIS)

    Perkins, R.B.

    1981-01-01

    The Los Alamos Scientific Laboratory Inertial Confinement Fusion Program is reviewed. Experiments using the Helios CO 2 laser system delivering up to 6kJ on target are described. Because breakeven energy estimates for laser drivers of 1 μm and above have risen and there is a need for CO 2 experiments in the tens-of-kJ regime as soon as practical, a first phase of Antares construction is now directed toward completion of two of the six original modules in 1983. These modules are designed to deliver 40kJ of CO 2 laser light on target. (author)

  15. Pulsed power driven hohlraum research at Sandia National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Leeper, R J; Alberts, T E; Allshouse, G A [Sandia Labs., Albuquerque, NM (United States); and others

    1997-12-31

    Three pulsed power driven hohlraum concepts are being investigated at Sandia National Laboratories. These hohlraums are driven by intense proton and Li ion beams as well as by two different types of z-pinch x-ray sources. The paper is an overview of the experiments that have been conducted on these hohlraum systems and discusses several new and novel hohlraum characterization diagnostics that have been developed for this work. These diagnostics include an active shock breakout measurement of hohlraum temperature and a new transmission grating spectrograph for detailed thermal radiation spectral measurements. (author). 3 figs., 6 refs.

  16. Pulsed power driven hohlraum research at Sandia National Laboratories

    International Nuclear Information System (INIS)

    Leeper, R.J.; Alberts, T.E.; Allshouse, G.A.

    1996-01-01

    Three pulsed power driven hohlraum concepts are being investigated at Sandia National Laboratories. These hohlraums are driven by intense proton and Li ion beams as well as by two different types of z-pinch x-ray sources. The paper is an overview of the experiments that have been conducted on these hohlraum systems and discusses several new and novel hohlraum characterization diagnostics that have been developed for this work. These diagnostics include an active shock breakout measurement of hohlraum temperature and a new transmission grating spectrograph for detailed thermal radiation spectral measurements. (author). 3 figs., 6 refs

  17. A New Model for Transitioning Students from the Undergraduate Teaching Laboratory to the Research Laboratory

    Science.gov (United States)

    Hollenbeck, Jessica J.; Wixson, Emily N.; Geske, Grant D.; Dodge, Matthew W.; Tseng, T. Andrew; Clauss, Allen D.; Blackwell, Helen E.

    2006-01-01

    The transformation of 346 chemistry courses into a training experience that could provide undergraduate students with a skill set essential for a research-based chemistry career is presented. The course has an innovative structure that connects undergraduate students with graduate research labs at the semester midpoint and also includes new,…

  18. About the Associate Director for Health of EPA's National Health and Environmental Effects Research Laboratory (NHEERL)

    Science.gov (United States)

    Dr. Ronald Hines serves as Associate Director for Health for the National Health and Environmental Effects Research Laboratory (NHEERL) within the U.S. Environmental Protection Agency's Office of Research and Development (ORD).

  19. About the Director of EPA's National Health and Environmental Effects Research Laboratory (NHEERL)

    Science.gov (United States)

    Dr. Wayne Cascio serves as Acting Director for the National Health and Environmental Effects Research Laboratory (NHEERL) within the U.S. Environmental Protection Agency's Office of Research and Development (ORD).

  20. Frontiers: Research highlights 1946-1996 [50th Anniversary Edition. Argonne National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This special edition of 'Frontiers' commemorates Argonne National Laboratory's 50th anniversary of service to science and society. America's first national laboratory, Argonne has been in the forefront of U.S. scientific and technological research from its beginning. Past accomplishments, current research, and future plans are highlighted.

  1. ICP/AES radioactive sample analyses at Pacific Northwest Laboratory

    International Nuclear Information System (INIS)

    Matsuzaki, C.L.; Hara, F.T.

    1986-03-01

    Inductively coupled argon plasma atomic emission spectroscopy (ICP/AES) analyses of radioactive materials at Pacific Northwest Laboratory (PNL) began about three years ago upon completion of the installation of a modified Applied Research Laboratory (ARL) 3560. Funding for the purchase and installation of the ICP/AES was provided by the Nuclear Waste Materials Characterization Center (MCC) established at PNL by the Department of Energy in 1979. MCC's objective is to ensure that qualified materials data are available on waste materials. This paper is divided into the following topics: (1) Instrument selection considerations; (2) initial installation of the simultaneous system with the source stand enclosed in a 1/2'' lead-shielded glove box; (3) retrofit installation of the sequential spectrometer; and (4) a brief discussion on several types of samples analyzed. 1 ref., 7 figs., 1 tab

  2. National Renewable Energy Laboratory (NREL) 2006 Research Review

    Energy Technology Data Exchange (ETDEWEB)

    2007-07-01

    This 2006 issue of the NREL Research Review again reveals just how vital and diverse our research portfolio has become. Our feature story looks at how our move to embrace the tenants of "translational research" is strengthening our ability to meet the nation's energy goals. By closing the gap between basic science and applied research and development (R&D)--and focusing a bright light on the valuable end uses of our work--translational research promises to shorten the time it takes to push new technology off the lab bench and into the marketplace. This issue also examines our research into fuels of the future and our computer modeling of wind power deployment, both of which point out the real-world benefits of our work.

  3. Lawrence Berkeley Laboratory research highlights for FY 1975

    Energy Technology Data Exchange (ETDEWEB)

    Sessler, Andrew M.

    1978-01-01

    Brief, nontechnical reviews are presented of work in the following areas: solar energy projects, fusion research, silicon cell research, superconducting magnetometers, psi particles, positron--electron project (PEP), pulsar measurements, nuclear dynamics, element 106, computer control of accelerators, the Bevalac biomedical facility, blood--lipid analysis, and bungarotoxin and the brain. Financial data and personnel lists are given, along with citations to well over a thousand research papers. (RWR)

  4. Lawrence Berkeley Laboratory research highlights for FY 1975

    International Nuclear Information System (INIS)

    Brief, nontechnical reviews are presented of work in the following areas: solar energy projects, fusion research, silicon cell research, superconducting magnetometers, psi particles, positron--electron project (PEP), pulsar measurements, nuclear dynamics, element 106, computer control of accelerators, the Bevalac biomedical facility, blood--lipid analysis, and bungarotoxin and the brain. Financial data and personnel lists are given, along with citations to well over a thousand research papers

  5. Studies on engineering technologies in the Mizunami Underground Research Laboratory. FY 2007 (Contract research)

    International Nuclear Information System (INIS)

    Noda, Masaru; Suyama, Yasuhiro; Nobuto, Jun; Ijiri, Yuji; Mikake, Shinichiro; Matsui, Hiroya

    2009-07-01

    The Mizunami Underground Research Laboratory (MIU) of the Japan Atomic Energy Agency is a major site for geoscientific research to advance the scientific and technological basis for geological disposal of high-level radioactive waste in crystalline rock. Studies on relevant engineering technologies in the MIU consist of a) research on design and construction technology for very deep underground applications, and b) research on engineering technology as a basis of geological disposal. In the Second Phase of the MIU project (the construction phase), engineering studies have focused on research into design and construction technologies for deep underground. The main subjects in the study of very deep underground structures consist of the following: 'Demonstration of the design methodology', 'Demonstration of existing and supplementary excavation methods', 'Demonstration of countermeasures during excavation' and 'Demonstration of safe construction'. In the FY 2007 studies, identification and evaluation of the subjects for study of engineering technologies in the construction phase were carried out to optimize future research work. Specific studies included: validation of the existing design methodology based on data obtained during construction; validation of existing and supplementary rock excavation methods for very deep shafts; estimation of rock stability under high differential water pressures, methodology on long-term maintenance of underground excavations and risk management systems for construction of underground structures have been performed. Based on these studies, future research focused on the four subject areas, which are 'Demonstration of the design methodology', 'Demonstration of existing and supplementary excavation methods', 'Demonstration of countermeasures during excavation' and 'Demonstration of safe construction', has been identified. The design methodology in the first phase of the MIU Project (surface-based investigation phase) was verified to

  6. Semiconductor research capabilities at the Lawrence Berkeley Laboratory

    International Nuclear Information System (INIS)

    1987-02-01

    This document discusses semiconductor research capabilities (advanced materials, processing, packaging) and national user facilities (electron microscopy, heavy-ion accelerators, advanced light source)

  7. Structural Insights into Arl1-Mediated Targeting of the Arf-GEF BIG1 to the trans-Golgi

    Directory of Open Access Journals (Sweden)

    Antonio Galindo

    2016-07-01

    Full Text Available The GTPase Arf1 is the major regulator of vesicle traffic at both the cis- and trans-Golgi. Arf1 is activated at the cis-Golgi by the guanine nucleotide exchange factor (GEF GBF1 and at the trans-Golgi by the related GEF BIG1 or its paralog, BIG2. The trans-Golgi-specific targeting of BIG1 and BIG2 depends on the Arf-like GTPase Arl1. We find that Arl1 binds to the dimerization and cyclophilin binding (DCB domain in BIG1 and report a crystal structure of human Arl1 bound to this domain. Residues in the DCB domain that bind Arl1 are required for BIG1 to locate to the Golgi in vivo. DCB domain-binding residues in Arl1 have a distinct conformation from those in known Arl1-effector complexes, and this plasticity allows Arl1 to interact with different effectors of unrelated structure. The findings provide structural insight into how Arf1 GEFs, and hence active Arf1, achieve their correct subcellular distribution.

  8. Labograph - a miniature radiography laboratory for education and research

    International Nuclear Information System (INIS)

    Krishnamurthy, K.; Muralidharan, P.; Aggarwal, K.S.

    1977-01-01

    The features of a compact self-contained low cost radiographic unit designed at the Bhabha Atomic Research Centre, Bombay, to meet the growing needs of educational and research requirements of colleges and engineering institutions within the country are described. Some of the regular applications and potential uses of the unit are discussed. (author)

  9. Pulsed power driven hohlraum research at Sandia National Laboratories

    International Nuclear Information System (INIS)

    Leeper, R.J.; Alberts, T.E.; Allshouse, G.A.

    1996-01-01

    Three pulsed power driven hohlraum concepts are being investigated at Sandia for application to inertial fusion research. These hohlraums are driven by intense proton and Li ion beams as well as by two different types of z-pinch x-ray sources. Research on these hohlraum systems will continue on Sandia's PBFA II-Z facility

  10. Role of ArlRS in autolysis in methicillin-sensitive and methicillin-resistant Staphylococcus aureus strains.

    Science.gov (United States)

    Memmi, Guido; Nair, Dhanalakshmi R; Cheung, Ambrose

    2012-02-01

    Autolysis plays an essential role in bacterial cell division and lysis with β-lactam antibiotics. Accordingly, the expression of autolysins is tightly regulated by several endogenous regulators, including ArlRS, a two component regulatory system that has been shown to negatively regulate autolysis in methicillin-sensitive Staphylococcus aureus (MSSA) strains. In this study, we found that inactivation of arlRS does not play a role in autolysis of methicillin-resistant S. aureus (MRSA) strains, such as community-acquired (CA)-MRSA strains USA300 and MW2 or the hospital-acquired (HA)-MRSA strain COL. This contrasts with MSSA strains, including Newman, SH1000, RN6390, and 8325-4, where autolysis is affected by ArlRS. We further demonstrated that the striking difference in the roles of arlRS between MSSA and MRSA strains is not due to the methicillin resistance determinant mecA. Among known autolysins and their regulators, we found that arlRS represses lytN, while no effect was seen on atl, lytM, and lytH expression in both CA- and HA-MRSA strains. Transcriptional-fusion assays showed that the agr transcripts, RNAII and RNAIII, were significantly more downregulated in the arlRS mutant of MW2 than the MSSA strain Newman. Importantly, provision of agr RNAIII in trans to the MW2 arlRS mutant via a multicopy plasmid induced autolysis in this MRSA strain. Also, the autolytic phenotype in the arlRS mutant of MSSA strain Newman could be rescued by a mutation in either atl or lytM. Together, these data showed that ArlRS impacts autolysis differently in MSSA and MRSA strains.

  11. The need for a quality standard for assurance in medical research laboratories

    Directory of Open Access Journals (Sweden)

    S Cohen

    2014-01-01

    Full Text Available The objective of this article is to show the results of a research study conducted to evaluate the need for a quality standard specific for medical research laboratories based on the shortfalls of ISO 15189 when used for this purpose. A qualitative research methodology was used, which comprised of collecting data from 20 well-qualified and experienced medical laboratory personnel by means of interviews based on a framework developed from a literature review. The data were analysed by means of a thematic technique and the results were verified by a team of medical researchers. The seven themes arising from the analyses were inflexibility; ambiguity; unfair requirements; inappropriate focus; inadequacy for research; renewal; and acceptance for accreditation. The results indicated that the ISO 15189 standard in its present content does not totally suit medical research laboratories and shows support for the development of a standard specific for research laboratories.

  12. Research and service capabilities of the National Nuclear Forensic Research Laboratory

    International Nuclear Information System (INIS)

    Romero G, E. T.; Hernandez M, H.; Flores C, J.; Paredes G, L. C.

    2016-09-01

    According to the recommendations of the International Atomic Energy Agency, Mexico is taking steps to combat illicit trafficking in nuclear material. The creation of a National Nuclear Forensic Research Laboratory (Lanafonu, acronym in Spanish) has been assigned to the Instituto Nacional de Investigaciones Nucleares (ININ, Mexico) in 2014. The objectives of this Laboratory are: to combat illicit trafficking in nuclear materials, to optimize scientific processes and techniques used to analyze nuclear materials (orphans or radioactive sources), environmental and potential biological sources as a result of the handling, transport and final storage. At present, the Lanafonu facilities are focused on the optimization of emergency and routine protocols for measuring radioisotopes in environmental and biological samples using inductive coupling mass spectrometer with magnetic sector. The main activities are: i) optimization of the methods for measuring the isotopes of Pu by alpha-spectrometry, Icp-SFMS and AMS (accelerator mass spectrometry), ii) development or radiochemical methods for routine situations and nuclear emergencies, iii) participation in the scientific technical commission on nuclear forensic science, iv) participation in international intercomparison exercises to optimize and validate methods, and v) consolidation of Lanafonu in Mexico and the IAEA. (Author)

  13. The Horonobe Underground Research Laboratory (Tentative name) Project. A program on survey and research performed from earth surface

    International Nuclear Information System (INIS)

    2001-03-01

    The Horonobe Underground Research Laboratory (Tentative name) Project under planning at Horonobe-machi by the Japan Nuclear Cycle Development Institute (JNC) is a research facility on deep underground shown in the Long-term program on research, development and application of nuclear energy (June, 1994)' (LPNE), where some researches on the deep underground targeted at sedimentary rocks are carried out. The plan on The Horonobe Underground Research Laboratory performed at Horonobe-machi' is an about 20 years plan ranging from beginning to finishing of its survey and research, which is carried out by three steps such as 'Survey and research performed from earth surface', 'Survey and research performed under excavation of road', and Survey and research performed by using the road'. The Horonobe Underground Research Laboratory is one of research facilities on deep underground shown its importance in LPNE, and carries out some researches on the deep underground at a target of the sedimentary rocks. And also The Horonobe Underground Research Laboratory confirms some technical reliability and support on stratum disposal shown in the 'Technical reliability on stratum disposal of the high level radioactive wastes. The Second Progress Report of R and D on geological disposal' summarized on November, 1999 by JNC through actual tests and researches at the deep stratum. The obtained results are intended to reflect to disposal business of The Horonobe Underground Research Laboratory and safety regulation and so on performed by the government, together with results of stratum science research, at the Tono Geoscience Center, of geological disposal R and D at the Tokai Works, or of international collaborations. For R and D at the The Horonobe Underground Research Laboratory after 2000, following subjects are shown: 1) Survey technique on long-term stability of geological environment, 2) Survey technique on geological environment, 3) Engineering technique on engineered barrier and

  14. Annual report of Nuclear Engineering Research Laboratory, University of Tokyo in fiscal 1992

    International Nuclear Information System (INIS)

    1993-07-01

    In this annual report, the activities of education and research, the state of operation of research facilities and others in Nuclear Engineering Research Laboratory, University of Tokyo in fiscal year 1992 are summarized. In this Laboratory, there are four large research facilities, that are, the fast neutron source reactor 'Yayoi', the electron beam linac, the nuclear fusion reactor blanket experiment facility and the heavy irradiation research facility. Those are used for carrying out education and research in the wide fields of nuclear engineering, and are offered also for joint utilization. The results of research by using respective research facilities have been summarized in separate reports. The course of the management and operation of each research facility is described, and the research activities, the theses for doctorate and graduation these of teachers, personnel and graduate students in the Laboratory are summarized. (J.P.N.)

  15. Interior Architectural Requirements for Electronic Circuits and its Applications Research Laboratory

    International Nuclear Information System (INIS)

    ElDib, A.A.

    2014-01-01

    This paper discusses the pivotal role of the Interior Architecture As one of the scientific disciplines minute to complete the Architectural Sciences, which relied upon the achievement and development of facilities containing scientific research laboratories, in terms of planning and design, particularly those containing biological laboratories using radioactive materials, adding to that, the application of the materials or raw materials commensurate with each discipline of laboratory and its work nature, and by the discussion the processing of design techniques and requirements of interior architecture dealing with Research Laboratory for electronic circuits and their applications with the making of its prototypes

  16. The small G protein Arl5 contributes to endosome-to-Golgi traffic by aiding the recruitment of the GARP complex to the Golgi

    Directory of Open Access Journals (Sweden)

    Cláudia Rosa-Ferreira

    2015-03-01

    Full Text Available The small G proteins of the Arf family play critical roles in membrane trafficking and cytoskeleton organization. However, the function of some members of the family remains poorly understood including Arl5 which is widely conserved in eukaryotes. Humans have two closely related Arl5 paralogues (Arl5a and Arl5b, and both Arl5a and Arl5b localize to the trans-Golgi with Arl5b being involved in retrograde traffic from endosomes to the Golgi apparatus. To investigate the function of Arl5, we have used Drosophila melanogaster as a model system. We find that the single Arl5 orthologue in Drosophila also localizes to the trans-Golgi, but flies lacking the Arl5 gene are viable and fertile. By using both liposome and column based affinity chromatography methods we find that Arl5 interacts with the Golgi-associated retrograde protein (GARP complex that acts in the tethering of vesicles moving from endosomes to the trans-Golgi network (TGN. In Drosophila tissues the GARP complex is partially displaced from the Golgi when Arl5 is absent, and the late endosomal compartment is enlarged. In addition, in HeLa cells GARP also becomes cytosolic upon depletion of Arl5b. These phenotypes are consistent with a role in endosome-to-Golgi traffic, but are less severe than loss of GARP itself. Thus it appears that Arl5 is one of the factors that directs the recruitment of the GARP complex to the trans-Golgi, and this function is conserved in both flies and humans.

  17. Change in Leadership at the Frederick National Laboratory | Frederick National Laboratory for Cancer Research

    Science.gov (United States)

    RESTON, Va., Oct. 26, 2017 /PRNewswire/ -- Leidos (NYSE: LDOS), a FORTUNE 500® science and technology company, announced today that Ethan Dmitrovsky, M.D. was appointed President of subsidiary Leidos Biomedical Research, Inc. (Leidos Biomed) a

  18. Ecological research at the Savannah River Ecology Laboratory. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-05-01

    Research is organized around two major programs: thermal and aquatic stress and mineral cycling. These programs are strengthened by a previously established foundation of basic ecological knowledge. Research in basic ecology continues to be a major component of all SREL environmental programs. Emphasis in all programs has been placed upon field-oriented research relating to regional and local problems having broad ecological significance. For example, extensive research has been conducted in the Par Pond reservoir system and the Savannah River swamp, both of which have received thermal effluent, heavy metals, and low levels of radioisotopes. Furthermore, the availability of low levels of plutonium and uranium in both terrestrial and aquatic environments on the Savannah River Plant (SRP) has provided an unusual opportunity for field research in this area. The studies seek to document the effects, to determine the extent of local environmental problems, and to establish predictable relationships which have general applicability. In order to accomplish this objective it has been imperative that studies be carried out in the natural, environmentally unaffected areas on the SRP as a vital part of the overall program. Progress is reported in forty-nine studies.

  19. Synchrotron radiation applications in medical research at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    Thomlinson, W.

    1997-08-01

    In the relatively short time that synchrotrons have been available to the scientific community, their characteristic beams of UV and X-ray radiation have been applied to virtually all areas of medical science which use ionizing radiation. The ability to tune intense monochromatic beams over wide energy ranges clearly differentiates these sources from standard clinical and research tools. The tunable spectrum, high intrinsic collimation of the beams, polarization and intensity of the beams make possible in-vitro and in-vivo research and therapeutic programs not otherwise possible. From the beginning of research operation at the National Synchrotron Light Source (NSLS), many programs have been carrying out basic biomedical research. At first, the research was limited to in-vitro programs such as the x-ray microscope, circular dichroism, XAFS, protein crystallography, micro-tomography and fluorescence analysis. Later, as the coronary angiography program made plans to move its experimental phase from SSRL to the NSLS, it became clear that other in-vivo projects could also be carried out at the synchrotron. The development of SMERF (Synchrotron Medical Research Facility) on beamline X17 became the home not only for angiography but also for the MECT (Multiple Energy Computed Tomography) project for cerebral and vascular imaging. The high energy spectrum on X17 is necessary for the MRT (Microplanar Radiation Therapy) experiments. Experience with these programs and the existence of the Medical Programs Group at the NSLS led to the development of a program in synchrotron based mammography. A recent adaptation of the angiography hardware has made it possible to image human lungs (bronchography). Fig. 1 schematically depicts the broad range of active programs at the NSLS

  20. LLNL (Lawrence Livermore National Laboratory) research on cold fusion

    Energy Technology Data Exchange (ETDEWEB)

    Thomassen, K I; Holzrichter, J F [eds.

    1989-09-14

    With the appearance of reports on Cold Fusion,'' scientists at the Lawrence Livermore National Laboratory (LLNL) began a series of increasingly sophisticated experiments and calculations to explain these phenomena. These experiments can be categorized as follows: (a) simple experiments to replicate the Utah results, (b) more sophisticated experiments to place lower bounds on the generation of heat and production of nuclear products, (c) a collaboration with Texas A M University to analyze electrodes and electrolytes for fusion by-products in a cell producing 10% excess heat (we found no by-products), and (d) attempts to replicate the Frascati experiment that first found neutron bursts when high-pressure deuterium gas in a cylinder with Ti chips was temperature-cycled. We failed in categories (a) and (b) to replicate either the Pons/Fleischmann or the Jones phenomena. We have seen phenomena similar to the Frascati results, (d) but these low-level burst signals may not be coming from neutrons generated in the Ti chips. Summaries of our experiments are described in Section II, as is a theoretical effort based on cosmic ray muons to describe low-level neutron production. Details of the experimental groups' work are contained in the six appendices. At LLNL, independent teams were spontaneously formed in response to the early announcements on cold fusion. This report's format follows this organization.

  1. Laboratory training manual on the use of nuclear techniques in pesticide research

    International Nuclear Information System (INIS)

    1983-01-01

    This is a laboratory training manual on the use of nuclear techniques, and in particular radioisotopes in pesticide research. It is designed to give the scientists involved in pesticide research the basic terms and principles for understanding ionizing radiation: detection and measurement its hazards and safety measures, and some of the more common applications. Laboratory exercises representing the types of experiments that are valuable in pesticide research programmes and field tests which demonstrate the use of radiolabelled pesticides are included

  2. University of Illinois at Urbana-Champaign, Materials Research Laboratory progress report for FY 1991

    International Nuclear Information System (INIS)

    1991-10-01

    The Materials Research Laboratory at the University of Illinois is an interdisciplinary laboratory operated in the College of Engineering. Its focus is the science of materials and it supports research in the areas of condensed matter physics, solid state chemistry, and materials science. This report addresses topics such as: an MRL overview; budget; general programmatic and institutional issues; new programs; research summaries for metallurgy, ceramics, solid state physics, and materials chemistry

  3. University of Illinois at Urbana-Champaign, Materials Research Laboratory progress report for FY 1991

    Energy Technology Data Exchange (ETDEWEB)

    1991-10-01

    The Materials Research Laboratory at the University of Illinois is an interdisciplinary laboratory operated in the College of Engineering. Its focus is the science of materials and it supports research in the areas of condensed matter physics, solid state chemistry, and materials science. This report addresses topics such as: an MRL overview; budget; general programmatic and institutional issues; new programs; research summaries for metallurgy, ceramics, solid state physics, and materials chemistry.

  4. Nuclear physics and heavy element research at Lawrence Livermore National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Stoyer, Mark A; Ahle, L E; Becker, J A; Bernshein, L A; Bleuel, D L; Burke, J T; Dashdorj, D; Henderson, R A; Hurst, A M; Kenneally, Jacqueline M; Lesher, S R; Moody, K J; Nelson, S L; Norman, E B; Pedretti, M; Scielzo, N D; Shaughnessy, D A; Sheets, S A; Stoeffl, W; Stoyer, N J [Lawrence Livermore National Laboratory, University of California, Livermore (United States)

    2009-12-31

    This paper highlights some of the current basic nuclear physics research at Lawrence Livermore National Laboratory (LLNL). The work at LLNL concentrates on investigating nuclei at the extremes. The Experimental Nuclear Physics Group performs research to improve our understanding of nuclei, nuclear reactions, nuclear decay processes and nuclear astrophysics; an expertise utilized for important laboratory national security programs and for world-class peer-reviewed basic research.

  5. Robotics Laboratory to Enhance the STEM Research Experience

    Science.gov (United States)

    2015-04-30

    Research Platforms Clearpath Robotics 2 $66,118 Open IMU system integrated with Husky SICK LMS Outdoor LIDAR Outdoor PTZ Camera NovAtel...currently focusing our attention and efforts on simultaneous localization and mapping ( SLAM ) algorithms, obstacle avoidance, and communication between

  6. National Renewable Energy Laboratory 2002 Research Review (Booklet)

    Energy Technology Data Exchange (ETDEWEB)

    Cook, G.; Epstein, K.; Brown, H.

    2002-07-01

    America is making a long transition to a future in which conventional, fossil fuel technologies will be displaced by new renewable energy and energy efficiency technologies. This first biannual research review describes NREL's R&D in seven technology areas--biorefineries, transportation, hydrogen, solar electricity, distributed energy, energy-efficient buildings, and low-wind-speed turbines.

  7. Fission product source term research at Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Malinauskas, A.P.

    1985-01-01

    The purpose of this work is to describe some of the research being performed at ORNL in support of the effort to describe, as realistically as possible, fission product source terms for nuclear reactor accidents. In order to make this presentation manageable, only those studies directly concerned with fission product behavior, as opposed to thermal hydraulics, accident sequence progression, etc., will be discussed

  8. Translating University Biosensor Research to a High School Laboratory Experience

    Science.gov (United States)

    Heldt, Caryn L.; Bank, Alex; Turpeinen, Dylan; King, Julia A.

    2016-01-01

    The need to increase science, technology, engineering, and mathematics (STEM) graduates is great. To interest more students into STEM degrees, we made our graphene biosensor research portable, inexpensive, and safe to demonstrate technology development to high school students. The students increased their knowledge of biosensors and proteins, and…

  9. Los Alamos National Laboratory Weapons Neutron Research Facility

    International Nuclear Information System (INIS)

    Woods, R.

    1981-01-01

    The Weapons Neutron Research (WNR) spallation neutron source utilizes 800-MeV protons from the Los Alamos Meson Physics linac. The proton beam transport system, the target systems, and the data acquisition and control system are described. Operating experience, present status, and planned improvements are discussed

  10. Horonobe Underground Research Laboratory project. Synthesis of phase I investigation 2001-2005. Volume 'geoscientific research'

    International Nuclear Information System (INIS)

    Ota, Kunio; Abe, Hironobu; Kunimaru, Takanori

    2011-03-01

    The Horonobe Underground Research Laboratory (URL) Project is being pursued by the Japan Atomic Energy Agency (JAEA) to enhance the reliability of relevant disposal technologies through investigations of the deep geological environment within the host sedimentary formations at Horonobe in Hokkaido, northern Japan. The project consists of two major research areas, 'Geoscientific Research' and 'R and D on Geological Disposal', and proceeds in three overlapping phases, 'Phase I: Surface-based investigation', 'Phase II: Construction' and 'Phase III: Operation', over a period of 20 years. The present report summarises the results of the Phase I geoscientific research carried out from March 2001 to March 2005. Integration of the results from different disciplines ensures that the Phase I goals have been successfully achieved and identifies key issues that need to be addressed in Phases II and III. More importantly, efforts are made to summarise as many lessons learnt from the Phase I investigations and other technical achievements as possible to form a 'knowledge base' that will reinforce the technical basis for both implementation and the formulation of safety regulations. Based on experiences of selecting the URL area and site in Horonobe Town, important factors that should be taken into consideration in such selection processes and their rationale are demonstrated. In the course of stepwise surface-based investigations, a number of achievements have been made, which can eventually provide examples of integrated methodologies for characterising the sedimentary formations. The relevant surface-based investigation techniques have thus been further developed. The Horonobe URL has been designed based on geoscientific information accumulated during the surface-based investigations and the plans for safe construction and operation of the URL have been defined in a feasible manner. In addition, a variety of environmental measures taken during Phase I have proved to be

  11. RLE (Research Laboratory of Electronics) Progress Report Number 130

    Science.gov (United States)

    1988-07-01

    Ippen, James G. Fujimoto, Wei-Zhu Lin, Beat Zysset, Robert W. Schoenlein, 4 Michael J. Lagasse The investigation of transient carrier dynamics in GaAs...G. Fujimoto, Wei-Zhu Lin, Reginald Birngruber, Beat Zysset, Robert W. Schoenleln Working in collaboration with researchers at the Massachusetts Eye... Binaural Hearing National Institutes of Health (Grant 5 RO 1 NS 10916) H. Steven Colburn, Nathaniel 1. Durlach, Patrick M. Zurek 17 Brooklyn College14 141

  12. RLE (Research Laboratory of Electronics) Progress Report Number 126.

    Science.gov (United States)

    1984-01-01

    Loudness 184 26.3 Binaural Hearing 186 S.26.4 Hearing Aid Research 188 26.5 Discrimination of Spectral Shape 191 26.6 Tactile Perception of Speech... beating in the pulse. It is these high intensities which are responsible for large A.C. Stark shifts and ionization RLE P.R. No. 126 12 * . . . Atomic...Department of Aeronautics and Astronautics, Massachusetts Institute of Technology, 1984. 26.3 Binaural Hearing National Institutes of Health (Grant

  13. FY 1999 Laboratory Directed Research and Development annual report

    International Nuclear Information System (INIS)

    PJ Hughes

    2000-01-01

    A short synopsis of each project is given covering the following main areas of research and development: Atmospheric sciences; Biotechnology; Chemical and instrumentation analysis; Computer and information science; Design and manufacture engineering; Ecological science; Electronics and sensors; Experimental technology; Health protection and dosimetry; Hydrologic and geologic science; Marine sciences; Materials science; Nuclear science and engineering; Process science and engineering; Sociotechnical systems analysis; Statistics and applied mathematics; and Thermal and energy systems

  14. FY 1999 Laboratory Directed Research and Development annual report

    Energy Technology Data Exchange (ETDEWEB)

    PJ Hughes

    2000-06-13

    A short synopsis of each project is given covering the following main areas of research and development: Atmospheric sciences; Biotechnology; Chemical and instrumentation analysis; Computer and information science; Design and manufacture engineering; Ecological science; Electronics and sensors; Experimental technology; Health protection and dosimetry; Hydrologic and geologic science; Marine sciences; Materials science; Nuclear science and engineering; Process science and engineering; Sociotechnical systems analysis; Statistics and applied mathematics; and Thermal and energy systems.

  15. Development and enhancement of grouting technologies in the Mizunami Underground Research Laboratory (Contract research)

    International Nuclear Information System (INIS)

    Nobuto, Jun; Mikake, Shinichiro

    2008-03-01

    In the Tono Geoscience Center of Japan Atomic Energy Agency (hereafter, JAEA), Mizunami Underground Research Laboratory project is being advanced to develop a scientific and technological basis for geological disposal. The concept of geological disposal is based on a multi-barrier system which combines a stable geological environment with an engineered barrier system (EBS). In order to develop a engineering basis for the construction of disposal system, the enhancement of grouting technologies among engineering technologies is needed. In this study, the comprehensive performance of suspension type grouting materials to seal rock fractures encountered in excavation works at deep underground has been checked, and the clogging phenomenon at the entrance of rock fractures has been investigated following the previous year. Research issues are as follows; Study on grouting concept to secure high-level water sealing, study on the test method to check grout clogging under high injection pressure, study on grouting material which can penetrate into finer fractures. Among these, in the study on penetrability test method, prototype test instruments were made and a series of preliminary tests were conducted. (author)

  16. How Work Positions Affect the Research Activity and Information Behaviour of Laboratory Scientists in the Research Lifecycle: Applying Activity Theory

    Science.gov (United States)

    Kwon, Nahyun

    2017-01-01

    Introduction: This study was conducted to investigate the characteristics of research and information activities of laboratory scientists in different work positions throughout a research lifecycle. Activity theory was applied as the conceptual and analytical framework. Method: Taking a qualitative research approach, in-depth interviews and field…

  17. Bridging the Gap between Instructional and Research Laboratories: Teaching Data Analysis Software Skills through the Manipulation of Original Research Data

    Science.gov (United States)

    Hansen, Sarah J. R.; Zhu, Jieling; Karch, Jessica M.; Sorrento, Cristina M.; Ulichny, Joseph C.; Kaufman, Laura J.

    2016-01-01

    The gap between graduate research and introductory undergraduate teaching laboratories is often wide, but the development of teaching activities rooted within the research environment offers an opportunity for undergraduate students to have first-hand experience with research currently being conducted and for graduate students to develop…

  18. Pacific Northwest Laboratory: Director`s overview of research performed for DOE Office of Health And Environmental Research

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    A significant portion of the research undertaken at Pacific Northwest Laboratory (PNL) is focused on the strategic programs of the US Department of Energy`s (DOE) Office of Health and Environmental Research (OHER). These programs, which include Environmental Processes (Subsurface Science, Ecosystem Function and Response, and Atmospheric Chemistry), Global Change (Climate Change, Environmental Vulnerability, and Integrated Assessments), Biotechnology (Human Genome and Structural Biology), and Health (Health Effects and Medical Applications), have been established by OHER to support DOE business areas in science and technology and environmental quality. PNL uses a set of critical capabilities based on the Laboratory`s research facilities and the scientific and technological expertise of its staff to help OHER achieve its programmatic research goals. Integration of these capabilities across the Laboratory enables PNL to assemble multidisciplinary research teams that are highly effective in addressing the complex scientific and technical issues associated with OHER-sponsored research. PNL research efforts increasingly are focused on complex environmental and health problems that require multidisciplinary teams to address the multitude of time and spatial scales found in health and environmental research. PNL is currently engaged in research in the following areas for these OHER Divisions: Environmental Sciences -- atmospheric radiation monitoring, climate modeling, carbon cycle, atmospheric chemistry, ecological research, subsurface sciences, bioremediation, and environmental molecular sciences; Health Effects and Life Sciences -- cell/molecular biology, and biotechnology; Medical Applications and Biophysical Research -- analytical technology, and radiological and chemical physics. PNL`s contributions to OHER strategic research programs are described in this report.

  19. ORNLs Laboratory Directed Research and Development Program FY 2010 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2011-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2010. The associated FY 2010 ORNL LDRD Self-Assessment (ORNL/PPA-2011/2) provides financial data and an internal evaluation of the program’s management process.

  20. ORNLs Laboratory Directed Research and Development Program FY 2009 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2010-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2009. The associated FY 2009 ORNL LDRD Self-Assessment (ORNL/PPA-2010/2) provides financial data and an internal evaluation of the program’s management process.

  1. ORNLs Laboratory Directed Research and Development Program FY 2008 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2009-03-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2008. The associated FY 2008 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and an internal evaluation of the program’s management process.

  2. ORNLs Laboratory Directed Research and Development Program FY 2013 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2014-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2013. The associated FY 2013 ORNL LDRD Self-Assessment (ORNL/PPA-2014/2) provides financial data and an internal evaluation of the program’s management process.

  3. ORNLs Laboratory Directed Research and Development Program FY 2012 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2013-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2012. The associated FY 2012 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial data and an internal evaluation of the program’s management process.

  4. ORNLs Laboratory Directed Research and Development Program FY 2011 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2012-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2011. The associated FY 2011 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial data and an internal evaluation of the program’s management process.

  5. Catalog of Research Abstracts, 1993: Partnership opportunities at Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The 1993 edition of Lawrence Berkeley Laboratory`s Catalog of Research Abstracts is a comprehensive listing of ongoing research projects in LBL`s ten research divisions. Lawrence Berkeley Laboratory (LBL) is a major multi-program national laboratory managed by the University of California for the US Department of Energy (DOE). LBL has more than 3000 employees, including over 1000 scientists and engineers. With an annual budget of approximately $250 million, LBL conducts a wide range of research activities, many that address the long-term needs of American industry and have the potential for a positive impact on US competitiveness. LBL actively seeks to share its expertise with the private sector to increase US competitiveness in world markets. LBL has transferable expertise in conservation and renewable energy, environmental remediation, materials sciences, computing sciences, and biotechnology, which includes fundamental genetic research and nuclear medicine. This catalog gives an excellent overview of LBL`s expertise, and is a good resource for those seeking partnerships with national laboratories. Such partnerships allow private enterprise access to the exceptional scientific and engineering capabilities of the federal laboratory systems. Such arrangements also leverage the research and development resources of the private partner. Most importantly, they are a means of accessing the cutting-edge technologies and innovations being discovered every day in our federal laboratories.

  6. The Augmented Reality Sandtable (ARES) Research Strategy

    Science.gov (United States)

    2018-02-01

    2014. Report No.: ARL-TR-6905. Creswell JW. Research design: qualitative , quantitative, and mixed methods approaches. 4th ed. Thousand Oaks (CA): Sage...an interface designed with UDOP principles. Research should seek to better understand the types of information relevant to certain classes of users...visualization research area, there are at least a few colleagues at ARL who are also conducting research in various types of (and combinations of

  7. Surveys of research in the Chemistry Division, Argonne National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Grazis, B.M. [ed.

    1992-11-01

    Research reports are presented on reactive intermediates in condensed phase (radiation chemistry, photochemistry), electron transfer and energy conversion, photosynthesis and solar energy conversion, metal cluster chemistry, chemical dynamics in gas phase, photoionization-photoelectrons, characterization and reactivity of coal and coal macerals, premium coal sample program, chemical separations, heavy elements coordination chemistry, heavy elements photophysics/photochemistry, f-electron interactions, radiation chemistry of high-level wastes (gas generation in waste tanks), ultrafast molecular electronic devices, and nuclear medicine. Separate abstracts have been prepared. Accelerator activites and computer system/network services are also reported.

  8. Surveys of research in the Chemistry Division, Argonne National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Grazis, B.M. (ed.)

    1992-01-01

    Research reports are presented on reactive intermediates in condensed phase (radiation chemistry, photochemistry), electron transfer and energy conversion, photosynthesis and solar energy conversion, metal cluster chemistry, chemical dynamics in gas phase, photoionization-photoelectrons, characterization and reactivity of coal and coal macerals, premium coal sample program, chemical separations, heavy elements coordination chemistry, heavy elements photophysics/photochemistry, f-electron interactions, radiation chemistry of high-level wastes (gas generation in waste tanks), ultrafast molecular electronic devices, and nuclear medicine. Separate abstracts have been prepared. Accelerator activites and computer system/network services are also reported.

  9. Materials Science and Engineering-1989 Publications (Naval Research Laboratory)

    Science.gov (United States)

    1991-03-29

    Antamanide J.H. Konnert, P. D’Antonio, J.M. Cowley, and Analog. Crystal Structure of A. Higgs , H-J. Ou Perhydrosymmetric antamanide, Ultramicroscopy, 30, 371...Paired Boson Superconductor" Molecular Beam Epitaxy" W. Jin, S.D. Mahanti, A.K. Rajagopal A. Christou, N. Flevaris, A. Georgakilas, Solid State...33(3), 347-358 Si(100)" "Neutron Scattering from Fermion and S.M. Prokes, W.F. Tseng, A- Christou Boson Superconductors" Materials Research Society

  10. A Hybrid Integrated Laboratory and Inquiry-Based Research Experience: Replacing Traditional Laboratory Instruction with a Sustainable Student-Led Research Project

    Science.gov (United States)

    Hartings, Matthew R.; Fox, Douglas M.; Miller, Abigail E.; Muratore, Kathryn E.

    2015-01-01

    The Department of Chemistry at American University has replaced its junior- and senior-level laboratory curriculum with two, two-semester long, student-led research projects as part of the department's American Chemical Society-accredited program. In the first semester of each sequence, a faculty instructor leads the students through a set of…

  11. Testing painted wood : past practices at the Forest Products Laboratory and recommendations for future research

    Science.gov (United States)

    R. Sam Williams

    2009-01-01

    A brief history of paint research at the Forest Products Laboratory (FPL) in Madison, Wisconsin, sets the stage for a discussion of testing paint on wood and wood products. Tests include laboratory and outdoor tests, and I discuss them in terms of several degradation mechanisms (loss of gloss and fading, mildew growth, extractives bleed, and cracking, flaking, and...

  12. Introducing Students to Psychological Research: General Psychology as a Laboratory Course

    Science.gov (United States)

    Thieman, Thomas J.; Clary, E. Gil; Olson, Andrea M.; Dauner, Rachel C.; Ring, Erin E.

    2009-01-01

    For 6 years, we have offered an integrated weekly laboratory focusing on research methods as part of our general psychology course. Through self-report measures and controlled comparisons, we found that laboratory projects significantly increase students' knowledge and comfort level with scientific approaches and concepts, sustain interest in…

  13. Developing Digital Courseware for a Virtual Nano-Biotechnology Laboratory: A Design-Based Research Approach

    Science.gov (United States)

    Yueh, Hsiu-Ping; Chen, Tzy-Ling; Lin, Weijane; Sheen, Horn-Jiunn

    2014-01-01

    This paper first reviews applications of multimedia in engineering education, especially in laboratory learning. It then illustrates a model and accreditation criteria adopted for developing a specific set of nanotechnology laboratory courseware and reports the design-based research approach used in designing and developing the e-learning…

  14. Forest Products Laboratory : supporting the nation's armed forces with valuable wood research for 90 years

    Science.gov (United States)

    Christopher D. Risbrudt; Robert J. Ross; Julie J. Blankenburg; Charles A. Nelson

    2007-01-01

    Founded in 1910 by the U.S. Forest Service to serve as a centralized, national wood research laboratory, the USDA Forest Products Laboratory (FPL) has a long history of providing technical services to other government agencies, including those within the Defense (DoD). A recent search of FPL’s library and correspondence files revealed that approximately 10,000...

  15. Writing Material in Chemical Physics Research: The Laboratory Notebook as Locus of Technical and Textual Integration

    Science.gov (United States)

    Wickman, Chad

    2010-01-01

    This article, drawing on ethnographic study in a chemical physics research facility, explores how notebooks are used and produced in the conduct of laboratory science. Data include written field notes of laboratory activity; visual documentation of "in situ" writing processes; analysis of inscriptions, texts, and material artifacts produced in the…

  16. The GATO gene annotation tool for research laboratories

    Directory of Open Access Journals (Sweden)

    A. Fujita

    2005-11-01

    Full Text Available Large-scale genome projects have generated a rapidly increasing number of DNA sequences. Therefore, development of computational methods to rapidly analyze these sequences is essential for progress in genomic research. Here we present an automatic annotation system for preliminary analysis of DNA sequences. The gene annotation tool (GATO is a Bioinformatics pipeline designed to facilitate routine functional annotation and easy access to annotated genes. It was designed in view of the frequent need of genomic researchers to access data pertaining to a common set of genes. In the GATO system, annotation is generated by querying some of the Web-accessible resources and the information is stored in a local database, which keeps a record of all previous annotation results. GATO may be accessed from everywhere through the internet or may be run locally if a large number of sequences are going to be annotated. It is implemented in PHP and Perl and may be run on any suitable Web server. Usually, installation and application of annotation systems require experience and are time consuming, but GATO is simple and practical, allowing anyone with basic skills in informatics to access it without any special training. GATO can be downloaded at [http://mariwork.iq.usp.br/gato/]. Minimum computer free space required is 2 MB.

  17. Open Air Laboratories (OPAL): A community-driven research programme

    Energy Technology Data Exchange (ETDEWEB)

    Davies, L., E-mail: l.davies@imperial.ac.uk [Imperial College London, London SW7 2AZ (United Kingdom); Bell, J.N.B.; Bone, J.; Head, M.; Hill, L. [Imperial College London, London SW7 2AZ (United Kingdom); Howard, C. [Natural History Museum, London SW7 5BD (United Kingdom); Hobbs, S.J. [Environment Department, University of York, Heslington, York YO10 5DD (United Kingdom); Jones, D.T. [Imperial College London, London SW7 2AZ (United Kingdom); Natural History Museum, London SW7 5BD (United Kingdom); Power, S.A. [Imperial College London, London SW7 2AZ (United Kingdom); Rose, N. [Department of Geography, University College London, London WC1E 6BT (United Kingdom); Ryder, C.; Seed, L. [Imperial College London, London SW7 2AZ (United Kingdom); Stevens, G. [Natural History Museum, London SW7 5BD (United Kingdom); Toumi, R.; Voulvoulis, N. [Imperial College London, London SW7 2AZ (United Kingdom); White, P.C.L. [Environment Department, University of York, Heslington, York YO10 5DD (United Kingdom)

    2011-08-15

    OPAL is an English national programme that takes scientists into the community to investigate environmental issues. Biological monitoring plays a pivotal role covering topics of: i) soil and earthworms; ii) air, lichens and tar spot on sycamore; iii) water and aquatic invertebrates; iv) biodiversity and hedgerows; v) climate, clouds and thermal comfort. Each survey has been developed by an inter-disciplinary team and tested by voluntary, statutory and community sectors. Data are submitted via the web and instantly mapped. Preliminary results are presented, together with a discussion on data quality and uncertainty. Communities also investigate local pollution issues, ranging from nitrogen deposition on heathlands to traffic emissions on roadside vegetation. Over 200,000 people have participated so far, including over 1000 schools and 1000 voluntary groups. Benefits include a substantial, growing database on biodiversity and habitat condition, much from previously unsampled sites particularly in urban areas, and a more engaged public. - Highlights: > Environmental research conducted jointly by the public and scientists. > Over 200,000 people involved, 8000 sites surveyed, uncertainty minimised. > New insights into urban pollution. > A more engaged and informed society. - Research is enriched where the public and scientists work together.

  18. Open Air Laboratories (OPAL): A community-driven research programme

    International Nuclear Information System (INIS)

    Davies, L.; Bell, J.N.B.; Bone, J.; Head, M.; Hill, L.; Howard, C.; Hobbs, S.J.; Jones, D.T.; Power, S.A.; Rose, N.; Ryder, C.; Seed, L.; Stevens, G.; Toumi, R.; Voulvoulis, N.; White, P.C.L.

    2011-01-01

    OPAL is an English national programme that takes scientists into the community to investigate environmental issues. Biological monitoring plays a pivotal role covering topics of: i) soil and earthworms; ii) air, lichens and tar spot on sycamore; iii) water and aquatic invertebrates; iv) biodiversity and hedgerows; v) climate, clouds and thermal comfort. Each survey has been developed by an inter-disciplinary team and tested by voluntary, statutory and community sectors. Data are submitted via the web and instantly mapped. Preliminary results are presented, together with a discussion on data quality and uncertainty. Communities also investigate local pollution issues, ranging from nitrogen deposition on heathlands to traffic emissions on roadside vegetation. Over 200,000 people have participated so far, including over 1000 schools and 1000 voluntary groups. Benefits include a substantial, growing database on biodiversity and habitat condition, much from previously unsampled sites particularly in urban areas, and a more engaged public. - Highlights: → Environmental research conducted jointly by the public and scientists. → Over 200,000 people involved, 8000 sites surveyed, uncertainty minimised. → New insights into urban pollution. → A more engaged and informed society. - Research is enriched where the public and scientists work together.

  19. Government-industry-uUniversity and rResearch lLaboratories cCoordination for new product development: Session 2. Government research laboratory perspective

    International Nuclear Information System (INIS)

    Kuzay, T.M.

    1997-01-01

    This talk is the second in an expanded series of presentations on the Government-Industry-University and Research Laboratories Coordination for new product development, which is a timely and important public policy issue. Such interactions have become particularly timely in light of the present decline in funding for research and development (R ampersand D) in the nation''s budget and in the private sector. These interactions, at least in principle, provide a means to maximize benefits for the greater good of the nation by pooling the diminishing resources. National laboratories, which traditionally interacted closely with the universities in educational training, now are able to also participate closely with industry in joint R ampersand D thanks to a number of public laws legislated since the early 80s. A review of the experiences with such interactions at Argonne National Laboratory, which exemplifies the national laboratories, shows that, despite differences in their traditions and the missions, the national laboratory-industry-university triangle can work together

  20. Chief, Structural Biophysics Laboratory | Center for Cancer Research

    Science.gov (United States)

    The SBL Chief is expected to establish a strong research program in structural biology/biophysics in addition to providing leadership of the SBL and the structural biology community in the NCI Intramural Program.  Applicants should hold a Ph.D., M.D./Ph.D., or equivalent doctoral degree in a relevant discipline, and should possess outstanding communication skills and documented leadership experience.  Tenured faculty or industrial scientists of equivalent rank with a demonstrated commitment to structural biophysics should apply.  Salary will be commensurate with experience and accomplishments.  This position is not restricted to U.S. citizens. A full civil service package of benefits (including health insurance, life insurance, and retirement) is available. This position is subject to a background investigation.  The NIH is dedicated to building a diverse community in its training and employment programs.

  1. An update on the Boston Marathon as a research laboratory.

    Science.gov (United States)

    Panza, Gregory A; Taylor, Beth A; Zaleski, Amanda L; Thompson, Paul D

    2015-07-01

    The Boston Athletic Association's annual marathon, also referred to as BAA in this article, continues to be a source of subjects for exercise and endurance performance research. We performed a systematic literature review of BAA studies published in the 7 years since our prior report. We identified 20 articles published from January 2008 to February 2015. Nine were related to cardiology; six were related to exercise physiology; four were related to metabolism; and one was related to marathon qualifying times. As in our prior, report cardiovascular studies remained the dominant topic, but with risk factors for atherosclerosis and thrombosis as the present focus. Cardiac issues remain the largest subject area for BAA studies, but with more emphasis on the effect of prolonged exercise on atherosclerotic and thrombotic risk factors. This shift is associated with an increase in marathon participation by older, recreational runners at increased risk of cardiac complications due to exercise.

  2. Retrospect over past 25 years at Research Laboratory for Nuclear Reactors, Tokyo Institute of Technology

    International Nuclear Information System (INIS)

    Aoki, Shigebumi

    1983-01-01

    Research Laboratory for Nuclear Reactors, Tokyo Institute of Technology, was established on April 1, 1956, with the aims of the investigation on the peaceful use of nuclear energy and of the education of scientists and engineers in this field. This report reviews the history of the Laboratory during 25 years and traces the process of growth concerning research divisions, buildings, large-scale experimental facilities and the education in the graduate course for nuclear engineering. In addition, considering what the Laboratory has to be and what the future plan will be, it is mentioned that the research interest should be extended to the field of nuclear fusion reactor, especially the blanket engineering, as a long-term future project of the Research Laboratory. (author)

  3. Summaries of the Idaho National Engineering Laboratory Radioecology and Ecology Program research projects

    International Nuclear Information System (INIS)

    Markham, O.D.

    1987-06-01

    This report provides summaries of individual research projects conducted by the Idaho National Engineering Laboratory Radioecology and Ecology Program. Summaries include projects in various stages, from those that are just beginning, to projects that are in the final publication stage

  4. Laboratory Directed Research & Development Program. Annual report to the Department of Energy, Revised December 1993

    Energy Technology Data Exchange (ETDEWEB)

    Ogeka, G.J.; Romano, A.J.

    1993-12-01

    At Brookhaven National Laboratory the Laboratory Directed Research and Development (LDRD) Program is a discretionary research and development tool critical in maintaining the scientific excellence and vitality of the laboratory. It is also a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor in achieving and maintaining staff excellence, and a means to address national needs, within the overall mission of the Department of Energy and Brookhaven National Laboratory. This report summarizes research which was funded by this program during fiscal year 1993. The research fell in a number of broad technical and scientific categories: new directions for energy technologies; global change; radiation therapies and imaging; genetic studies; new directions for the development and utilization of BNL facilities; miscellaneous projects. Two million dollars in funding supported 28 projects which were spread throughout all BNL scientific departments.

  5. An overview of Quality Management System implementation in a research laboratory

    Science.gov (United States)

    Molinéro-Demilly, Valérie; Charki, Abdérafi; Jeoffrion, Christine; Lyonnet, Barbara; O'Brien, Steve; Martin, Luc

    2018-02-01

    The aim of this paper is to show the advantages of implementing a Quality Management System (QMS) in a research laboratory in order to improve the management of risks specific to research programmes and to increase the reliability of results. This paper also presents experience gained from feedback following the implementation of the Quality process in a research laboratory at INRA, the French National Institute for Agronomic Research and details the various challenges encountered and solutions proposed to help achieve smoother adoption of a QMS process. The 7Ms (Management, Measurement, Manpower, Methods, Materials, Machinery, Mother-nature) methodology based on the Ishikawa `Fishbone' diagram is used to show the effectiveness of the actions considered by a QMS, which involve both the organization and the activities of the laboratory. Practical examples illustrate the benefits and improvements observed in the laboratory.

  6. Teaching Laboratory and Research Skills as Preparation for Careers in Science and Education

    Science.gov (United States)

    Thoms, Brian

    2007-03-01

    Recipients of bachelor's degrees in physics have identified lab skills, team work, and research skills as abilities necessary for success in their jobs. However, they also report having received less than adequate preparation in these areas during their college careers. We report on the redesign of a junior physics-major modern physics laboratory course into an inquiry-based, research-like laboratory course. The overall strategy was such as to require the students to approach the experiments in a research-like fashion. In addition, experiments which explore materials properties which can't be looked up in textbooks, e.g. Hall Effect, have been added to further emphasize a research-like approach to the investigations. Laboratory reporting requirements were written to closely reproduce current practices in scientific journals. Assessment of the redesign was performed through surveys of current and graduated students and through comparison of laboratory reports.

  7. Laboratory Directed Research and Development Program. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    Ogeka, G.J.; Romano, A.J.

    1992-12-01

    This report briefly discusses the following research: Advances in Geoexploration; Transvenous Coronary Angiography with Synchrotron X-Rays; Borehole Measurements of Global Warming; Molecular Ecology: Development of Field Methods for Microbial Growth Rate and Activity Measurements; A New Malaria Enzyme - A Potential Source for a New Diagnostic Test for Malaria and a Target for a New Antimalarial Drug; Basic Studies on Thoron and Thoron Precursors; Cloning of the cDNA for a Human Serine/Threonine Protein Kinase that is Activated Specifically by Double-Stranded DNA; Development of an Ultra-Fast Laser System for Accelerator Applications; Cluster Impact Fusion; Effect of a Bacterial Spore Protein on Mutagenesis; Structure and Function of Adenovirus Penton Base Protein; High Resolution Fast X-Ray Detector; Coherent Synchrotron Radiation Longitudinal Bunch Shape Monitor; High Grain Harmonic Generation Experiment; BNL Maglev Studies; Structural Investigations of Pt-Based Catalysts; Studies on the Cellular Toxicity of Cocaine and Cocaethylene; Human Melanocyte Transformation; Exploratory Applications of X-Ray Microscopy; Determination of the Higher Ordered Structure of Eukaryotic Chromosomes; Uranium Neutron Capture Therapy; Tunneling Microscopy Studies of Nanoscale Structures; Nuclear Techiques for Study of Biological Channels; RF Sources for Accelerator Physics; Induction and Repair of Double-Strand Breaks in the DNA of Human Lymphocytes; and An EBIS Source of High Charge State Ions up to Uranium.

  8. Experimental facility of innovative types as the laboratory analog of research reactor experimental device

    International Nuclear Information System (INIS)

    Androsenko, A.A.; Androsenko, P.A.; Zabud'ko, A.N.; Kremenetskij, A.K.; Nikolaev, A.N.; Trykov, L.A.

    1991-01-01

    The paper analyses capability of creating laboratory analogs of complex experimental facilities at research reactors utilizing power radionuclide neutron sources fabricated in industrial conditions. Some experimental and calculational investigations of neutron-physical characteristics are presented, which have been attained at the RIZ research reactor laboratory analog. Experimental results are supplemented by calculational investigations, fulfilled by means of the BRAND three-dimensional computational complex and the ROZ-6 one-dimensional program. 4 refs.; 3 figs

  9. Laboratory experiments in innovation research: A methodological overview and a review of the current literature

    OpenAIRE

    Brüggemann, Julia; Bizer, Kilian

    2016-01-01

    Innovation research has developed a broad set of methodological approaches in recent decades. In this paper, we propose laboratory experiments as a fruitful methodological addition to the existing methods in innovation research. Therefore, we provide an overview of the existing methods, discuss the advantages and limitations of laboratory experiments, and review experimental studies dealing with different fields of innovation policy, namely intellectual property rights, financi...

  10. Development and Assessment of Green, Research-Based Instructional Materials for the General Chemistry Laboratory

    Science.gov (United States)

    Cacciatore, Kristen L.

    2010-01-01

    This research entails integrating two novel approaches for enriching student learning in chemistry into the context of the general chemistry laboratory. The first is a pedagogical approach based on research in cognitive science and the second is the green chemistry philosophy. Research has shown that inquiry-based approaches are effective in…

  11. Education and research at the Ohio State University nuclear reactor laboratory

    International Nuclear Information System (INIS)

    Miller, D.W.; Myser, R.D.; Talnagi, J.W.

    1989-01-01

    The educational and research activities at the Ohio State University Nuclear Reactor Laboratory (OSUNRL) are discussed in this paper. A brief description of an OSUNRL facility improvement program and its expected impact on research is presented. The overall long-term goal of the OSUNRL is to support the comprehensive education, research, and service mission of OSU

  12. The evolution of drug design at Merck Research Laboratories.

    Science.gov (United States)

    Brown, Frank K; Sherer, Edward C; Johnson, Scott A; Holloway, M Katharine; Sherborne, Bradley S

    2017-03-01

    On October 5, 1981, Fortune magazine published a cover article entitled the "Next Industrial Revolution: Designing Drugs by Computer at Merck". With a 40+ year investment, we have been in the drug design business longer than most. During its history, the Merck drug design group has had several names, but it has always been in the "design" business, with the ultimate goal to provide an actionable hypothesis that could be tested experimentally. Often the result was a small molecule but it could just as easily be a peptide, biologic, predictive model, reaction, process, etc. To this end, the concept of design is now front and center in all aspects of discovery, safety assessment and early clinical development. At present, the Merck design group includes computational chemistry, protein structure determination, and cheminformatics. By bringing these groups together under one umbrella, we were able to align activities and capabilities across multiple research sites and departments. This alignment from 2010 to 2016 resulted in an 80% expansion in the size of the department, reflecting the increase in impact due to a significant emphasis across the organization to "design first" along the entire drug discovery path from lead identification (LID) to first in human (FIH) dosing. One of the major advantages of this alignment has been the ability to access all of the data and create an adaptive approach to the overall LID to FIH pathway for any modality, significantly increasing the quality of candidates and their probability of success. In this perspective, we will discuss how we crafted a new strategy, defined the appropriate phenotype for group members, developed the right skillsets, and identified metrics for success in order to drive continuous improvement. We will not focus on the tactical implementation, only giving specific examples as appropriate.

  13. The evolution of drug design at Merck Research Laboratories

    Science.gov (United States)

    Brown, Frank K.; Sherer, Edward C.; Johnson, Scott A.; Holloway, M. Katharine; Sherborne, Bradley S.

    2017-03-01

    On October 5, 1981, Fortune magazine published a cover article entitled the "Next Industrial Revolution: Designing Drugs by Computer at Merck". With a 40+ year investment, we have been in the drug design business longer than most. During its history, the Merck drug design group has had several names, but it has always been in the "design" business, with the ultimate goal to provide an actionable hypothesis that could be tested experimentally. Often the result was a small molecule but it could just as easily be a peptide, biologic, predictive model, reaction, process, etc. To this end, the concept of design is now front and center in all aspects of discovery, safety assessment and early clinical development. At present, the Merck design group includes computational chemistry, protein structure determination, and cheminformatics. By bringing these groups together under one umbrella, we were able to align activities and capabilities across multiple research sites and departments. This alignment from 2010 to 2016 resulted in an 80% expansion in the size of the department, reflecting the increase in impact due to a significant emphasis across the organization to "design first" along the entire drug discovery path from lead identification (LID) to first in human (FIH) dosing. One of the major advantages of this alignment has been the ability to access all of the data and create an adaptive approach to the overall LID to FIH pathway for any modality, significantly increasing the quality of candidates and their probability of success. In this perspective, we will discuss how we crafted a new strategy, defined the appropriate phenotype for group members, developed the right skillsets, and identified metrics for success in order to drive continuous improvement. We will not focus on the tactical implementation, only giving specific examples as appropriate.

  14. A genome-wide association study reveals variants in ARL15 that influence adiponectin levels.

    Directory of Open Access Journals (Sweden)

    J Brent Richards

    2009-12-01

    Full Text Available The adipocyte-derived protein adiponectin is highly heritable and inversely associated with risk of type 2 diabetes mellitus (T2D and coronary heart disease (CHD. We meta-analyzed 3 genome-wide association studies for circulating adiponectin levels (n = 8,531 and sought validation of the lead single nucleotide polymorphisms (SNPs in 5 additional cohorts (n = 6,202. Five SNPs were genome-wide significant in their relationship with adiponectin (P< or =5x10(-8. We then tested whether these 5 SNPs were associated with risk of T2D and CHD using a Bonferroni-corrected threshold of P< or =0.011 to declare statistical significance for these disease associations. SNPs at the adiponectin-encoding ADIPOQ locus demonstrated the strongest associations with adiponectin levels (P-combined = 9.2x10(-19 for lead SNP, rs266717, n = 14,733. A novel variant in the ARL15 (ADP-ribosylation factor-like 15 gene was associated with lower circulating levels of adiponectin (rs4311394-G, P-combined = 2.9x10(-8, n = 14,733. This same risk allele at ARL15 was also associated with a higher risk of CHD (odds ratio [OR] = 1.12, P = 8.5x10(-6, n = 22,421 more nominally, an increased risk of T2D (OR = 1.11, P = 3.2x10(-3, n = 10,128, and several metabolic traits. Expression studies in humans indicated that ARL15 is well-expressed in skeletal muscle. These findings identify a novel protein, ARL15, which influences circulating adiponectin levels and may impact upon CHD risk.

  15. LABORATORY DIRECTED RESEARCH AND DEVELOPMENT ANNUAL REPORT TO THE DEPARTMENT OF ENERGY - DECEMBER 2006

    Energy Technology Data Exchange (ETDEWEB)

    FOX, K.J.

    2006-12-31

    Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's total annual budget has averaged about $460 million. There are about 2,500 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, ''Laboratory Directed Research and Development,'' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy National Nuclear Security Administration Laboratories dated June 13, 2006. In accordance this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2006.

  16. Synthesized research report in the second mid-term research phase. Mizunami Underground Research Laboratory project, Horonobe Underground Research Laboratory project and geo-stability project

    International Nuclear Information System (INIS)

    Hama, Katsuhiro; Sasao, Eiji; Iwatsuki, Teruki; Saegusa, Hiromitsu; Sato, Toshinori; Umeda, Koji; Yasue, Kenichi; Asamori, Koichi; Osawa, Hideaki; Koide, Kaoru; Nagae, Isako; Natsuyama, Ryoko; Mizuno, Takashi; Fujita, Tomoo; Sasamoto, Hiroshi; Matsuoka, Toshiyuki; Yokota, Hideharu; Ishii, Eiichi; Aoyagi, Kazuhei; Nakayama, Masashi; Ito, Hiroaki; Tsusaka, Kimikazu; Ohyama, Takuya; Senba, Takeshi; Amano, Kenji

    2015-08-01

    We have synthesised the research results from Mizunami/Horonobe URLs and geo-stability projects in the second mid-term research phase. It could be used as technical bases for NUMO/Regulator in each decision point from siting to beginning of disposal (Principal Investigation to Detailed Investigation Phase). High quality construction techniques and field investigation methods have been developed and implemented and these will be directly applicable to the National Disposal Program (along with general assessments of hazardous natural events and processes). It will be crucial to acquire technical knowledge on decisions of partial backfilling and final closure by actual field experiments in Mizunami/Horonobe URLs as main themes for the next phases. (author)

  17. LDRD 2013 Annual Report: Laboratory Directed Research and Development Program Activities

    Energy Technology Data Exchange (ETDEWEB)

    Bookless, W. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2013-12-31

    This LDRD project establishes a research program led by Jingguang Chen, who has started a new position as a Joint Appointee between BNL and Columbia University as of FY2013. Under this project, Dr. Chen will establish a new program in catalysis science at BNL and Columbia University. The LDRD program will provide initial research funding to start research at both BNL and Columbia. At BNL, Dr. Chen will initiate laboratory research, including hiring research staff, and will collaborate with the existing BNL catalysis and electrocatalysis research groups. At Columbia, a subcontract to Dr. Chen will provide startup funding for his laboratory research, including initial graduate student costs. The research efforts will be linked under a common Catalysis Program in Sustainable Fuels. The overall impact of this project will be to strengthen the BNL catalysis science program through new linked research thrusts and the addition of an internationally distinguished catalysis scientist.

  18. Management of water hyacinth. Report from India (Regional Research Laboratory, Jorhat, Assam)

    International Nuclear Information System (INIS)

    Baruah, J.N.

    1981-01-01

    The main objective of the project is the development of an environmentally sound management scheme for water hyacinth infestation through its various utilization potentials. Such an approach is considered desirable from the point ov view of economic viability and environmental protection. Accordingly various aspects of the problem have been studied in India in three different laboratories. Regional Research Laboratory, Jorhat, which is the lead laboratory, is concerned with the study of various factors involved in the growth of this weed, production of biogas, paper and board from water hyacinth, screening of compounds and organisms with commercial potential in this plant and utilization of this weed for mushroom cultivation. Developmental and engineering aspects of biogas production from water hyacinth are studied at Central Mechanical Engineering Research Institute, Durgapur, and Nagarjuna Sagar Engineering College, J N Technological University, Hyderabad. Pilot plant investigation on the production of handmade paper and board is being investigated at Regional Research Laboratory, Hyderabad

  19. The Advanced Interdisciplinary Research Laboratory: A Student Team Approach to the Fourth-Year Research Thesis Project Experience

    Science.gov (United States)

    Piunno, Paul A. E.; Boyd, Cleo; Barzda, Virginijus; Gradinaru, Claudiu C.; Krull, Ulrich J.; Stefanovic, Sasa; Stewart, Bryan

    2014-01-01

    The advanced interdisciplinary research laboratory (AIRLab) represents a novel, effective, and motivational course designed from the interdisciplinary research interests of chemistry, physics, biology, and education development faculty members as an alternative to the independent thesis project experience. Student teams are assembled to work…

  20. Revealing all: misleading self-disclosure rates in laboratory-based online research.

    Science.gov (United States)

    Callaghan, Diana E; Graff, Martin G; Davies, Joanne

    2013-09-01

    Laboratory-based experiments in online self-disclosure research may be inadvertently compromising the accuracy of research findings by influencing some of the factors known to affect self-disclosure behavior. Disclosure-orientated interviews conducted with 42 participants in the laboratory and in nonlaboratory settings revealed significantly greater breadth of self-disclosure in laboratory interviews, with message length and intimacy of content also strongly related. These findings suggest that a contrived online setting with a researcher presence may stimulate motivation for greater self-disclosure than would occur naturally in an online environment of an individual's choice. The implications of these findings are that researchers should consider the importance of experimental context and motivation in self-disclosure research.