WorldWideScience

Sample records for research instrumentation mri

  1. Nuclear instrumentation for research reactors

    International Nuclear Information System (INIS)

    Hofer, Carlos G.; Pita, Antonio; Verrastro, Claudio A.; Maino, Eduardo J.

    1997-01-01

    The nuclear instrumentation for research reactors in Argentina was developed in 70'. A gradual modernization of all the nuclear instrumentation is planned. It includes start-up and power range instrumentation, as well as field monitors, clamp, scram and rod movement control logic. The new instrumentation is linked to a computer network, based on real time operating system for data acquisition, display and logging. This paper describes the modules and whole system aspects. (author). 2 refs

  2. Usefulness of ACR MRI phantom for quality assurance of MRI instruments

    International Nuclear Information System (INIS)

    Lee, Jung Whee; Ahn, Kook Jin; Lee, Seung Koo; Na, Dong Gyu; Oh, Chang Hyun; Chang, Yong Min; Lim, Tae Hwan

    2006-01-01

    To examine whether the ACR phantom could be used in quality standards for magnetic resonance imaging (MRI) instruments in Korea. We conducted the phantom test using the ACR MRI phantom in 20 MRI instruments currently used in Korea. According to ACR criteria, we acquired the phantom images which were then assessed by the following seven tests: geometric accuracy, high spatial resolution, slice thickness accuracy, slice position accuracy, image intensity uniformity, percent signal ghosting, and low contrast object detectability. The phantom images were interpreted by three experienced radiologists according to ACR criteria. Then, we examined the failure rate of each test and evaluated the inter-observer variation in the measurements and test failure. The failure rate of each test could be broken into the following components: geometric accuracy (11-21%), high contrast spatial resolution (10-15%), slice thickness accuracy(6-22%), slice position accuracy (5-17%), image intensity uniformity (6%), percent signal ghosting (16%), and low contrast object detectability (8-10%). In this series, all the failure rates were less than 30%. In addition, no inter-observer variation was seen in the measurements and test failure. ACR MRI phantom promises to be established as the standard phantom for MRI instruments in Korea because of its objectivity in assessing the phantom images

  3. Research progress of functional MRI in depression

    International Nuclear Information System (INIS)

    Xie Shenghui; Niu Guangming; Han Xiaodong; Qiao Pengfei

    2013-01-01

    The mood disorders of depression are associated with abnormalities of brain structure and function, and exploring their pathological mechanism has important significance for the choice of treatment and the curative effect evaluation. In recent years, the research of MRI on brain structure and function of depression has made great progress, especially in functional magnetic resonance imaging (fMRI). fMRI can detect the functional change in real time, and also can display the activity of brain and changes in the nerve pathways in patients with depression. This article summarizes the present research situation and progress of MRI in the diagnosis of depression. (authors)

  4. Lung MRI for experimental drug research

    International Nuclear Information System (INIS)

    Beckmann, Nicolau; Cannet, Catherine; Karmouty-Quintana, Harry; Tigani, Bruno; Zurbruegg, Stefan; Ble, Francois-Xavier; Cremillieux, Yannick; Trifilieff, Alexandre

    2007-01-01

    Current techniques to evaluate the efficacy of potential treatments for airways diseases in preclinical models are generally invasive and terminal. In the past few years, the flexibility of magnetic resonance imaging (MRI) to obtain anatomical and functional information of the lung has been explored with the scope of developing a non-invasive approach for the routine testing of drugs in models of airways diseases in small rodents. With MRI, the disease progression can be followed in the same animal. Thus, a significant reduction in the number of animals used for experimentation is achieved, as well as minimal interference with their well-being and physiological status. In addition, under certain circumstances the duration of the observation period after disease onset can be shortened since the technique is able to detect changes before these are reflected in parameters of inflammation determined using invasive procedures. The objective of this article is to briefly address MRI techniques that are being used in experimental lung research, with special emphasis on applications. Following an introduction on proton techniques and MRI of hyperpolarized gases, the attention is shifted to the MRI analysis of several aspects of lung disease models, including inflammation, ventilation, emphysema, fibrosis and sensory nerve activation. The next subject concerns the use of MRI in pharmacological studies within the context of experimental lung research. A final discussion points towards advantages and limitations of MRI in this area

  5. Instrument Variables for Reducing Noise in Parallel MRI Reconstruction

    Directory of Open Access Journals (Sweden)

    Yuchou Chang

    2017-01-01

    Full Text Available Generalized autocalibrating partially parallel acquisition (GRAPPA has been a widely used parallel MRI technique. However, noise deteriorates the reconstructed image when reduction factor increases or even at low reduction factor for some noisy datasets. Noise, initially generated from scanner, propagates noise-related errors during fitting and interpolation procedures of GRAPPA to distort the final reconstructed image quality. The basic idea we proposed to improve GRAPPA is to remove noise from a system identification perspective. In this paper, we first analyze the GRAPPA noise problem from a noisy input-output system perspective; then, a new framework based on errors-in-variables (EIV model is developed for analyzing noise generation mechanism in GRAPPA and designing a concrete method—instrument variables (IV GRAPPA to remove noise. The proposed EIV framework provides possibilities that noiseless GRAPPA reconstruction could be achieved by existing methods that solve EIV problem other than IV method. Experimental results show that the proposed reconstruction algorithm can better remove the noise compared to the conventional GRAPPA, as validated with both of phantom and in vivo brain data.

  6. Instruments and accessories for neutron scattering research

    International Nuclear Information System (INIS)

    Ishii, Yoshinobu; Morii, Yukio

    2000-04-01

    This report describes neutron scattering instruments and accessories installed by four neutron scattering research groups at the ASRC (Advanced Science Research Center) of the JAERI and the recent topics of neutron scattering research using these instruments. The specifications of nine instruments (HRPD, BIX-I, TAS-1 and PNO in the reactor hall, RESA, BIX-II, TAS-2, LTAS and SANS-J in the guide hall of the JRR-3M) are summarized in this booklet. (author)

  7. Nuclear reactor instrumentation at research reactor renewal

    International Nuclear Information System (INIS)

    Baers, B.; Pellionisz, P.

    1981-10-01

    The paper overviews the state-of-the-art of research reactor renewals. As a case study the instrumentation reconstruction of the Finnish 250 kW TRIGA reactor is described, with particular emphasis on the nuclear control instrumentation and equipment which has been developed and manufactured by the Central Research Institute for Physics, Budapest. Beside the presentation of the nuclear instrument family developed primarily for research reactor reconstructions, the quality assurance policy conducted during the manufacturing process is also discussed. (author)

  8. Using Translated Instruments in Research

    Science.gov (United States)

    Beauford, Judith E.; Nagashima, Yosuke; Wu, Ming-Hsun

    2009-01-01

    The "need for global exchange" for research is apparent in all areas of study, both because of the global interchange of commerce and the improvements that can be accomplished worldwide as people learn from one another. The globalization of higher education includes cross-cultural research projects often conducted by teams from many countries and…

  9. Technical and instrumentational foundations of PET/MRI

    NARCIS (Netherlands)

    Rausch, Ivo; Quick, Harald H.; Cal-Gonzalez, Jacobo; Sattler, Bernhard; Boellaard, Ronald; Beyer, Thomas

    This paper highlights the origins of combined positron emission tomography (PET) and magnetic resonance imaging (MRI) whole-body systems that were first introduced for applications in humans in 2010. This text first covers basic aspects of each imaging modality before describing the technical and

  10. the research quality plus (rq+) assessment instrument

    International Development Research Centre (IDRC) Digital Library (Canada)

    Thomas Schwandt

    THE RESEARCH QUALITY PLUS (RQ+) ASSESSMENT INSTRUMENT ... consistent way to allow for further meta-analysis about research quality over time. ... Addresses complex and integrative problems, requiring systems-based approaches ..... benefits or financial costs for participants that might not be appropriate in the ...

  11. Learning the Concept of Researcher as Instrument in Qualitative Research

    Science.gov (United States)

    Xu, Mengxuan Annie; Storr, Gail Blair

    2012-01-01

    The authors describe the process whereby a student with a background in economics was guided to understand the central role in qualitative research of the researcher as instrument. The instructor designed a three-part mock research project designed to provide experiential knowledge of the enterprise of qualitative research. Students, as neophyte…

  12. Functional MRI in children: clinical and research applications

    International Nuclear Information System (INIS)

    Leach, James L.; Holland, Scott K.

    2010-01-01

    Functional MRI has become a critical research tool for evaluating brain function and developmental trajectories in children. Its clinical use in children is becoming more common. This presentation will review the basic underlying physiologic and technical aspects of fMRI, review research applications that have direct clinical relevance, and outline the current clinical uses of this technology. (orig.)

  13. Small animal MRI: clinical MRI as an interface to basic biomedical research

    International Nuclear Information System (INIS)

    Pinkernelle, J.G.; Stelter, L.; Hamm, B.; Teichgraeber, U.

    2008-01-01

    The demand for highly resolved small animal MRI for the purpose of biomedical research has increased constantly. Dedicated small animal MRI scanners working at ultra high field strengths from 4.7 to 7.0 T and even above are MRI at its best. However, using high resolution RF coils in clinical scanners up to 3.0 T, small animal MRI can achieve highly resolved images showing excellent tissue contrast. In fact, in abundant experimental studies, clinical MRI is used for small animal imaging. Mostly clinical RF coils in the single-loop design are applied. In addition, custom-built RF coils and even gradient inserts are used in a clinical scanner. For the reduction of moving artifacts, special MRI-compatible animal ECG und respiration devices are available. In conclusion, clinical devices offer broad availability, are less expense in combination with good imaging performance and provide a translational nature of imaging results. (orig.)

  14. Well logging instrumental and methodological research

    International Nuclear Information System (INIS)

    Andrassy, L.; Barath, I.; Dorko, R.

    1983-01-01

    This part of the Annual Report of the Roland Eoetvoes Geophysical Institute (ELGI) of Hungary for 1982, summarizes the well logging instrumental and methodological researches of ELGI. The theoretical neutron diffusion fluxes for black and brown coals of Hungarian mines were calculated. A coal probe was developed and tested in boreholes using computerized data processing and interpretation. An X-ray radiometric method was used for the determination of Cu and Fe contents of minerals. Researches in the field of magnetic susceptibility and induced polarization logging are also summarized. A rapid analyzer for bauxite mining and a photorecorder for petroleum industry were developed by ELGI. (D.Gy.)

  15. Solar Energy Research Center Instrumentation Facility

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, Thomas, J.; Papanikolas, John, P.

    2011-11-11

    SOLAR ENERGY RESEARCH CENTER INSTRUMENTATION FACILITY The mission of the Solar Energy Research Center (UNC SERC) at the University of North Carolina at Chapel Hill (UNC-CH) is to establish a world leading effort in solar fuels research and to develop the materials and methods needed to fabricate the next generation of solar energy devices. We are addressing the fundamental issues that will drive new strategies for solar energy conversion and the engineering challenges that must be met in order to convert discoveries made in the laboratory into commercially available devices. The development of a photoelectrosynthesis cell (PEC) for solar fuels production faces daunting requirements: (1) Absorb a large fraction of sunlight; (2) Carry out artificial photosynthesis which involves multiple complex reaction steps; (3) Avoid competitive and deleterious side and reverse reactions; (4) Perform 13 million catalytic cycles per year with minimal degradation; (5) Use non-toxic materials; (6) Cost-effectiveness. PEC efficiency is directly determined by the kinetics of each reaction step. The UNC SERC is addressing this challenge by taking a broad interdisciplinary approach in a highly collaborative setting, drawing on expertise across a broad range of disciplines in chemistry, physics and materials science. By taking a systematic approach toward a fundamental understanding of the mechanism of each step, we will be able to gain unique insight and optimize PEC design. Access to cutting-edge spectroscopic tools is critical to this research effort. We have built professionally-staffed facilities equipped with the state-of the-art instrumentation funded by this award. The combination of staff, facilities, and instrumentation specifically tailored for solar fuels research establishes the UNC Solar Energy Research Center Instrumentation Facility as a unique, world-class capability. This congressionally directed project funded the development of two user facilities: TASK 1: SOLAR

  16. Instrumentation for a radon research house

    International Nuclear Information System (INIS)

    Nazaroff, W.W.; Revzan, K.L.; Robb, A.W.

    1981-07-01

    A highly automated monitoring and control system for studying radon and radon-daughter behavior in residences has been designed and built. The system has been installed in a research house, a test space contained in a two-story wood-framed building, which allows us to conduct controlled studies of (1) pollutant transport within and between rooms, (2) the dynamics of radon daughter behavior, and (3) techniques for controlling radon and radon daughters. The system's instrumentation is capable of measuring air-exchange rate, four-point radon concentration, individual radon daughter concentrations, indoor temerature and humidity, and outdoor weather parameters (temperature, humidity, modules, wind speed, and wind direction). It is also equipped with modules that control the injection of radon and tracer gas into the test space, the operation of the forced-air furnace, the mechanical ventilation system, and the mixing fans located in each room. A microcomputer controls the experiments and records the data on magnetic tape and on a printing terminal. The data on tape is transferred to a larger computer system for reduction and analysis. In this paper we describe the essential design and function of the instrumentation system, as a whole, singling out those components that measure ventilation rate, radon concentration, and radon daughter concentrations

  17. ARM Climate Research Facility Monthly Instrument Report August 2010

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2010-09-28

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  18. ARM Climate Research Facility Instrumentation Status and Information October 2009

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2009-10-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  19. ARM Climate Research Facility Instrumentation Status and Information April 2010

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2010-05-15

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  20. ARM Climate Research Facility Instrumentation Status and Information January 2010

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2010-02-28

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  1. ARM Climate Research Facility Monthly Instrument Report September 2010

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2010-10-18

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  2. ARM Climate Research Facility Instrumentation Status and Information March 2010

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2010-04-19

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  3. ARM Climate Research Facility Monthly Instrument Report May 2010

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2010-06-21

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  4. ARM Climate Research Facility Instrumentation Status and Information February 2010

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2010-03-25

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  5. ARM Climate Research Facility Monthly Instrument Report June 2010

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2010-07-13

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  6. ARM Climate Research Facility Instrumentation Status and Information December 2009

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2010-12-30

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  7. ARM Climate Research Facility Monthly Instrument Report July 2010

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2010-08-18

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  8. Research progress on neural mechanisms of primary insomnia by MRI

    Directory of Open Access Journals (Sweden)

    Man WANG

    2018-04-01

    Full Text Available In recent years, more and more researches focused on the neural mechanism of primary insomnia (PI, especially with the development and application of MRI, and researches of brain structure and function related with primary insomnia were more and more in-depth. According to the hyperarousal hypothesis, there are abnormal structure, function and metabolism under certain brain regions of the cortex and subcortex of primary insomnia patients, including amygdala, hippocampus, cingulate gyrus, insular lobe, frontal lobe and parietal lobe. This paper reviewed the research progress of neural mechanisms of primary insomnia by using MRI. DOI: 10.3969/j.issn.1672-6731.2018.03.003

  9. Aerodynamics support of research instrument development

    Science.gov (United States)

    Miller, L. Scott

    1990-09-01

    A new velocimetry system is currently being developed at NASA LaRC. The device, known as a Doppler global velocimeter (DGV), can record three velocity components within a plane simultaneously and in near real time. To make measurements the DGV, like many other velocimetry systems, relies on the scattering of light from numerous small particles in a flow field. The particles or seeds are illuminated by a sheet of laser light and viewed by two CCD cameras. The scattered light from the particles will have a frequency which is a function of the source laser light frequency, the viewing angle, and most importantly the seed velocities. By determining the scattered light intensity the velocity can be measured at all points within the light sheet simultaneously. Upon completion of DGV component construction and initial check out a series of tests in the Basic Aerodynamic Research (wind) Tunnel (BART) are scheduled to verify instrument operation and accuracy. If the results are satisfactory, application of the DGV to flight measurements on the F-18 High Alpha Research Vehicle (HARV) are planned. The DGV verification test in the BART facility will utilize a 75 degree swept delta wing model. A major task undertaken this summer included evaluation of previous results for this model. A specific series of tests matching exactly the previous tests and exploring new DGV capabilities were developed and suggested. Another task undertaken was to study DGV system installation possibilities in the F-18 HARV aircraft. In addition, a simple seeding system modification was developed and utilized to make Particle Imaging Velocimetry (PIV) measurements in the BART facility.

  10. Strengthening the research and development on nursing instruments

    International Nuclear Information System (INIS)

    Liu Lanying; Zhao Changhe

    1999-01-01

    The current status about nursing instruments is described. The nursing work is an impotent part of medical treatments, especially in the treatment with radioactive isotopes. Some proposals concerning the future research and development of nursing instruments have been submitted

  11. An Attitude Scale on Individual Instrument and Individual Instrument Course: Validity-Reliability Research

    Science.gov (United States)

    Kuçukosmanoglu, Hayrettin Onur

    2015-01-01

    The main purpose of this study is to develop a scale to determine students' attitude levels on individual instruments and individual instrument courses in instrument training, which is an important dimension of music education, and to conduct a validity-reliability research of the scale that has been developed. The scale consists of 16 items. The…

  12. Digital instrumentation system for nuclear research reactors

    International Nuclear Information System (INIS)

    Aghina, Mauricio A.C.; Carvalho, Paulo Vitor R.

    2002-01-01

    This work describes a proposal for a system of nuclear instrumentation and safety totally digital for the Argonauta Reactor. The system divides in the subsystems: channel of pulses, channel of current, conventional instrumentation and safety system. The connection of the subsystems is made through redundant double local net, using the protocol modbus/rtu. So much the channel of pulses, the current channel and safety's system use modules operating in triple redundancy. (author)

  13. Instrumental neutron activation analysis in environmental research

    International Nuclear Information System (INIS)

    Bruin, M. de.

    1985-01-01

    The main characteristics of instrumental neutron activation analysis (INAA),relevant for environmental research and monitoring, was reviewed and discussed-sensitivity, suitable for detection of many toxic elements, the low risks of contamination of element loss, lack of matrix effects, lack of light element interference except for 24 Na, capability for multi-element determination, comparatively low costs. A detailed description of the IRI analysis system for routine INAA is given. The system is based on the single comparator method of standartization to take full advantage of multi-element without preparation and use the trace element standards. Zinc was used as mono element standard, the element concentrations are calculated on the basis of 65 Zn and 69m Zn-activities. The irradiations were carried out in a thermal neutron flux of 1.10 13 n/cm 2 .s. The gamma spectra is converted into element concentrations using a set of dedicated software, performing the following functions: spectrum analysis and interpretation, comparison and combination of the intermediate results from different decay times, generation of the final report, bookkeeping of the results obtained. The main applications of the INAA system mentioned are: identification of sources of heavy metal air pollution using air filters or biological indicators such as mosses, lichens, toe-nails, bird feathers, molusks and waterplants; and study of the uptake and translocation of heavy element in plants. Special attention was paid to mathematical techniques for a reliable interpretation of the element concentration patterns observed in sets of lichen samples. Future developments in INAA in environmental science are briefly mentioned

  14. The Global ECT-MRI Research Collaboration (GEMRIC)

    DEFF Research Database (Denmark)

    Oltedal, Leif; Bartsch, Hauke; Sørhaug, Ole Johan Evjenth

    2017-01-01

    biological factors relating to or predictive of ECT-related therapeutic response. We have thus formed the Global ECT-MRI Research Collaboration (GEMRIC) that aims to combine longitudinal neuroimaging as well as clinical, behavioral and other physiological data across multiple independent sites. Here, we...

  15. Research progress of BOLD-functional MRI of hepatic encephalopathy

    International Nuclear Information System (INIS)

    Ni Ling; Zhang Longjiang; Lu Guangming

    2013-01-01

    Hepatic encephalopathy (HE), characterized by a wide spectrum of clinical manifestations, ranging from behavior abnormality, conscious disorder and even coma, is a consequence of liver dysfunction in both acute and chronic hepatic diseases. Minimal hepatic encephalopathy (MHE) refers to a subgroup of cirrhotic patients without clinical overt hepatic encephalopathy symptoms hut with abnormalities in neuro -cognitive functions. HE/MHE can have a far-reaching impact on quality of life and prognosis. The exact neuropathology mechanism was still unclear. Recently, functional MRI (fMRI) has been increasingly applied for investigating the neuro-pathophysiological mechanism of HE. This paper will review the fMRI research applied on uncovering the neuropathology mechanism of HE. (authors)

  16. Instrumentation

    International Nuclear Information System (INIS)

    Decreton, M.

    2000-01-01

    SCK-CEN's research and development programme on instrumentation aims at evaluating the potentials of new instrumentation technologies under the severe constraints of a nuclear application. It focuses on the tolerance of sensors to high radiation doses, including optical fibre sensors, and on the related intelligent data processing needed to cope with the nuclear constraints. Main achievements in these domains in 1999 are summarised

  17. Proceedings of national symposium on advanced instrumentation for nuclear research

    International Nuclear Information System (INIS)

    1993-01-01

    The National Symposium on Advanced Instrumentation for Nuclear Research was held in Bombay during January 27-29, 1993 at BARC. Progress of modern nuclear research is closely related to the availability of state of the art instruments and systems. With the advancements in experimental techniques and sophisticated detector developments, the performance specifications have become more stringent. State of the art techniques and diverse applications of sophisticated nuclear instrumentation systems are discussed along with indigenous efforts to meet the specific instrumentation needs of research programs in nuclear sciences. Papers of relevance to nuclear science and technology are indexed separately. (original)

  18. Trends and developments in MRI contrast agent research

    International Nuclear Information System (INIS)

    Cavagna, F.M.; Dapra, M.; Castelli, P.M.; Maggioni, F.; Kirchin, M.A.

    1997-01-01

    The currently prevailing trends in industrial contrast agent research for MRI are discussed. Specific mention is made of contrast agents for liver imaging using both static and delayed procedures, of the potential for blood pool agents and the form such agents may take, and of the ultimate challenge for contrast agent R and D: tissue-targeting in a wider sense to both normal and pathologic tissues. (orig.)

  19. Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Decreton, M

    2001-04-01

    SCK-CEN's research and development programme on instrumentation involves the assessment and the development of sensitive measurement systems used within a radiation environment. Particular emphasis is on the assessment of optical fibre components and their adaptability to radiation environments. The evaluation of ageing processes of instrumentation in fission plants, the development of specific data evaluation strategies to compensate for ageing induced degradation of sensors and cable performance form part of these activities. In 2000, particular emphasis was on in-core reactor instrumentation applied to fusion, accelerator driven and water-cooled fission reactors. This involved the development of high performance instrumentation for irradiation experiments in the BR2 reactor in support of new instrumentation needs for MYRRHA, and for diagnostic systems for the ITER reactor.

  20. Instrumentation

    International Nuclear Information System (INIS)

    Decreton, M.

    2001-01-01

    SCK-CEN's research and development programme on instrumentation involves the assessment and the development of sensitive measurement systems used within a radiation environment. Particular emphasis is on the assessment of optical fibre components and their adaptability to radiation environments. The evaluation of ageing processes of instrumentation in fission plants, the development of specific data evaluation strategies to compensate for ageing induced degradation of sensors and cable performance form part of these activities. In 2000, particular emphasis was on in-core reactor instrumentation applied to fusion, accelerator driven and water-cooled fission reactors. This involved the development of high performance instrumentation for irradiation experiments in the BR2 reactor in support of new instrumentation needs for MYRRHA, and for diagnostic systems for the ITER reactor

  1. Antennas and Electromagnetics Instrumentation for Research and Education

    Science.gov (United States)

    2016-06-01

    Antennas and Electromagnetics Instrumentation for Research and Education The objective of this proposal is to enhance the instrumentation of FIU’s... ElectroMagnetics Lab (EMLab) directed by Dr. Georgakopoulos and create a state-of-the art lab that will support the following: (a) Dr. Georgakopoulos...funded research on reconfigurable antennas and wireless power transfer, (b) other research on advanced electromagnetic technologies that support

  2. Instrumentation renewal at the FIR 1 research reactor in Finland

    International Nuclear Information System (INIS)

    Bars, Bruno; Kall, Leif

    1982-01-01

    The Finnish TRIGA Mark II reactor (FIR 1 100 kW, later 250 kW steady state power and pulsing capability up to 250 MW) has been in operation for 20 years. The reactor is the only research reactor in Finland and is an important research training and service facility, which obviously will be operated for 10...20 years ahead. The mechanical parts of the reactor are in good shape. Some minor modifications have previously been made in the instrumentation. However, the original instrumentation could hardly have been used for 10...20 years ahead without extensive modifications and modernization. After a careful evaluation and planning process the whole reactor instrumentation was renewed in 1981 at a cost of about 400 000 dollar. The renewal was carried out in cooperation with the Central Research Institute for Physics (KFKI) at the Hungarian Academy of Sciences, which delivered the nuclear part of the instrumentation and with the Finnish company Valmet Oy Instrument Works, which delivered the conventional instrumentation, including the automatic power control system and the control console. The instrumentation, which is located in-a new isolated control room is based on modern industrial standard modular units with standardized signal ranges, electronic testing possibilities, galvanically isolated outputs etc. The instrument renewal project was brought successfully to completion in November 1981 after only about 10 working days of shut down time. The reactor is now in routine operation and the experiences gained from the new instrumentation are excellent. (author)

  3. Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Decreton, M

    2000-07-01

    SCK-CEN's research and development programme on instrumentation aims at evaluating the potentials of new instrumentation technologies under the severe constraints of a nuclear application. It focuses on the tolerance of sensors to high radiation doses, including optical fibre sensors, and on the related intelligent data processing needed to cope with the nuclear constraints. Main achievements in these domains in 1999 are summarised.

  4. Building a framework for ergonomic research on laparoscopic instrument handles.

    Science.gov (United States)

    Li, Zheng; Wang, Guohui; Tan, Juan; Sun, Xulong; Lin, Hao; Zhu, Shaihong

    2016-06-01

    Laparoscopic surgery carries the advantage of minimal invasiveness, but ergonomic design of the instruments used has progressed slowly. Previous studies have demonstrated that the handle of laparoscopic instruments is vital for both surgical performance and surgeon's health. This review provides an overview of the sub-discipline of handle ergonomics, including an evaluation framework, objective and subjective assessment systems, data collection and statistical analyses. Furthermore, a framework for ergonomic research on laparoscopic instrument handles is proposed to standardize work on instrument design. Copyright © 2016 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

  5. the research quality plus (rq+) assessment instrument

    International Development Research Centre (IDRC) Digital Library (Canada)

    sclarke

    These need to be taken into account as part of the assessment. 2. .... be cases in which there is not enough information available to make a credible ..... (within a research community) or for decision-making and problem-solving beyond the ...

  6. Falsification Testing of Instrumental Variables Methods for Comparative Effectiveness Research.

    Science.gov (United States)

    Pizer, Steven D

    2016-04-01

    To demonstrate how falsification tests can be used to evaluate instrumental variables methods applicable to a wide variety of comparative effectiveness research questions. Brief conceptual review of instrumental variables and falsification testing principles and techniques accompanied by an empirical application. Sample STATA code related to the empirical application is provided in the Appendix. Comparative long-term risks of sulfonylureas and thiazolidinediones for management of type 2 diabetes. Outcomes include mortality and hospitalization for an ambulatory care-sensitive condition. Prescribing pattern variations are used as instrumental variables. Falsification testing is an easily computed and powerful way to evaluate the validity of the key assumption underlying instrumental variables analysis. If falsification tests are used, instrumental variables techniques can help answer a multitude of important clinical questions. © Health Research and Educational Trust.

  7. Foundations of intervention research in instrumental practice

    Directory of Open Access Journals (Sweden)

    Johannes Lunde Hatfield

    2016-01-01

    Full Text Available The goals of the present study are to evaluate, implement, and adapt psychological skills used in the realm of sports into music performance. This research project also aims to build foundations on how to implement future interventions to guide music students on how to optimize practice toward performance. A two-month psychological skills intervention was provided to two students from the national music academy’s bachelor program in music performance to better understand how to adapt and construct psychological skills training programs for performing music students. The program evaluated multiple intervention tools including the use of questionnaires, performance profiling, iPads, electronic practice logs, recording the perceived value of individual and combined work, as well as the effectiveness of different communication forms. Perceived effects of the intervention were collected through semi-structured interviews, observations, and logs.

  8. Research on geothermal chemistry and advanced instrumentation

    Science.gov (United States)

    Robertus, R. J.; Shannon, D. W.; Sullivan, R. G.; Kindle, C. H.; Pool, K. H.

    1985-09-01

    Research at the Pacific Northwest Laboratory (PNL) focuses on long-term geothermal power plant reliability. Past work concentrated on development of continuous high-temperature probes for monitoring process variables. PNL also completed a comprehensive handbook of brine treatment processes as they relate to injection well longevity. A recently completed study analyzed corrosion in the hydrocarbon system of a binary cycle plant. Over the two-year monitoring period, corrosion rates were less than 1 MPY in any part of the hydrocarbon system. The system was kept completely dry so the rates seem reasonable. Present projects include: (1) determination of gas breakout conditions at the Herber Binary Demonstration Plant operated by San Diego Gas and Electric Company; (2) generation of water mixing solubility data; (3) installation of prototype leak detectors at the Herber Plant; and (4) evaluation of state-of-the-art particle counters.

  9. On-line Monitoring of Instrumentation in Research Reactors

    International Nuclear Information System (INIS)

    2017-12-01

    This publication is the result of a benchmarking effort undertaken under the IAEA coordinated research project on improved instrumentation and control (I&C) maintenance techniques for research reactors. It lays the foundation for implementation of on-line monitoring (OLM) techniques and establishment of the validity of those for improved maintenance practices in research reactors for a number of applications such as change to condition based calibration, performance monitoring of process instrumentation systems, detection of process anomalies and to distinguish between process problems/effects and instrumentation/sensor issues. The techniques and guidance embodied in this publication will serve the research reactor community in providing the technical foundation for implementation of OLM techniques. It is intended to be used by Member States to implement I&C maintenance and to improve performance of research reactors.

  10. MRI

    DEFF Research Database (Denmark)

    Schroeter, Aileen; Rudin, Markus; Gianolio, Eliana

    2017-01-01

    This chapter discusses principles of nuclear magnetic resonance (NMR) and MRI followed by a survey on the major classes of MRI contrast agents (CA), their modes of action, and some of the most significative applications. The two more established classes of MRI-CA are represented by paramagnetic...... been attained that markedly increase the number and typology of systems with CEST properties. Currently much attention is also devoted to hyperpolarized molecules that display a sensitivity enhancement sufficient for their direct exploitation for the formation of the MR image. A real breakthrough...

  11. MRI

    Science.gov (United States)

    ... the room. Pins, hairpins, metal zippers, and similar metallic items can distort the images. Removable dental work ... an MRI can cause heart pacemakers and other implants not to work as well. The magnets can ...

  12. Remote sensing technology research and instrumentation platform design

    Science.gov (United States)

    1992-01-01

    An instrumented pallet concept and definition of an aircraft with performance and payload capability to meet NASA's airborne turbulent flux measurement needs for advanced multiple global climate research and field experiments is presented. The report addresses airborne measurement requirements for general circulation model sub-scale parameterization research, specifies instrumentation capable of making these measurements, and describes a preliminary support pallet design. Also, a review of aircraft types and a recommendation of a manned and an unmanned aircraft capable of meeting flux parameterization research needs is given.

  13. Instrumentation

    International Nuclear Information System (INIS)

    Umminger, K.

    2008-01-01

    A proper measurement of the relevant single and two-phase flow parameters is the basis for the understanding of many complex thermal-hydraulic processes. Reliable instrumentation is therefore necessary for the interaction between analysis and experiment especially in the field of nuclear safety research where postulated accident scenarios have to be simulated in experimental facilities and predicted by complex computer code systems. The so-called conventional instrumentation for the measurement of e. g. pressures, temperatures, pressure differences and single phase flow velocities is still a solid basis for the investigation and interpretation of many phenomena and especially for the understanding of the overall system behavior. Measurement data from such instrumentation still serves in many cases as a database for thermal-hydraulic system codes. However some special instrumentation such as online concentration measurement for boric acid in the water phase or for non-condensibles in steam atmosphere as well as flow visualization techniques were further developed and successfully applied during the recent years. Concerning the modeling needs for advanced thermal-hydraulic codes, significant advances have been accomplished in the last few years in the local instrumentation technology for two-phase flow by the application of new sensor techniques, optical or beam methods and electronic technology. This paper will give insight into the current state of instrumentation technology for safety-related thermohydraulic experiments. Advantages and limitations of some measurement processes and systems will be indicated as well as trends and possibilities for further development. Aspects of instrumentation in operating reactors will also be mentioned.

  14. Design and Implementation of Data Collection Instruments for Neonatology Research

    Directory of Open Access Journals (Sweden)

    Monica G. HĂŞMĂŞANU

    2014-12-01

    Full Text Available im: The aim of our research was to design and implement data collection instruments to be use in context of an observational prospective clinical study with follow-up conducted on new born with intrauterine growth restriction. Methods: The structure of the data collection forms (paper based and electronic based was first identified and for each variable the best type to accomplish the research aim was established. The code for categorical variables has also been decided as well as the units of measurements for quantitative variables. In respect of good practice, a set of confounding factors (as gender, date of birth, etc. have also been identified and integrated in data collection instruments. Data-entry validation rules were implemented for each variable to reduce data input errors when the electronic data collection instrument was created. Results: Two data collection instruments have been developed and successfully implemented: a paper-based form and an electronic data collection instrument. The developed forms included demographics, neonatal complications (as hypoglycemia, hypocalcemia, etc., biochemical data at birth and follow-up, immunological data, as well as basal and follow-up echocardiographic data. Data-entry validation criteria have been implemented in electronic data collection instrument to assure validity and precision when paper-based data are translated in electronic form. Furthermore, to assure subject’s confidentiality a careful attention was given to HIPPA identifiers when electronic data collection instrument was developed. Conclusion: Data collection instruments were successfully developed and implemented as an a priori step in a clinical research for assisting data collection and management in a case of an observational prospective study with follow-up visits.

  15. Teen drivers' awareness of vehicle instrumentation in naturalistic research.

    Science.gov (United States)

    Ehsani, J P; Haynie, D; Ouimet, M C; Zhu, C; Guillaume, C; Klauer, S G; Dingus, T; Simons-Morton, B G

    2017-12-01

    Naturalistic driving methods require the installation of instruments and cameras in vehicles to record driving behavior. A critical, yet unexamined issue in naturalistic driving research is the extent to which the vehicle instruments and cameras used for naturalistic methods change human behavior. We sought to describe the degree to which teenage participants' self-reported awareness of vehicle instrumentation changes over time, and whether that awareness was associated with driving behaviors. Forty-two newly-licensed teenage drivers participated in an 18-month naturalistic driving study. Data on driving behaviors including crash/near-crashes and elevated gravitational force (g-force) events rates were collected over the study period. At the end of the study, participants were asked to rate the extent to which they were aware of instruments in the vehicle at four time points. They were also asked to describe their own and their passengers' perceptions of the instrumentation in the vehicle during an in-depth interview. The number of critical event button presses was used as a secondary measure of camera awareness. The association between self-reported awareness of the instrumentation and objectively measured driving behaviors was tested using correlations and linear mixed models. Most participants' reported that their awareness of vehicle instrumentation declined across the duration of the 18-month study. Their awareness increased in response to their passengers' concerns about the cameras or if they were involved in a crash. The number of the critical event button presses was initially high and declined rapidly. There was no correlation between driver's awareness of instrumentation and their crash and near-crash rate or elevated g-force events rate. Awareness was not associated with crash and near-crash rates or elevated g-force event rates, consistent with having no effect on this measure of driving performance. Naturalistic driving studies are likely to yield

  16. Research and Development on a Public Attitude Instrument for Stuttering

    Science.gov (United States)

    St. Louis, Kenneth O.

    2012-01-01

    This paper summarizes research associated with the development of the "Public Opinion Survey of Human Attributes-Stuttering" ("POSHA-S"), a survey instrument designed to provide a worldwide standard measure of public attitudes toward stuttering. Pilot studies with early experimental prototypes of the "POSHA-S" are summarized that relate to…

  17. Applied research of environmental monitoring using instrumental neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Young Sam; Moon, Jong Hwa; Chung, Young Ju

    1997-08-01

    This technical report is written as a guide book for applied research of environmental monitoring using Instrumental Neutron Activation Analysis. The contents are as followings; sampling and sample preparation as a airborne particulate matter, analytical methodologies, data evaluation and interpretation, basic statistical methods of data analysis applied in environmental pollution studies. (author). 23 refs., 7 tabs., 9 figs.

  18. Safety regulations concerning instrumentation and control systems for research reactors

    International Nuclear Information System (INIS)

    El-Shanshoury, A.I.

    2009-01-01

    A brief study on the safety and reliability issues related to instrumentation and control systems in nuclear reactor plants is performed. In response, technical and strategic issues are used to accomplish instrumentation and control systems safety. For technical issues there are ; systems aspects of digital I and C technology, software quality assurance, common-mode software, failure potential, safety and reliability assessment methods, and human factors and human machine interfaces. The strategic issues are the case-by-case licensing process and the adequacy of the technical infrastructure. The purpose of this work was to review the reliability of the safety systems related to these technical issues for research reactors

  19. Availability analysis of the nuclear instrumentation of a research reactor

    International Nuclear Information System (INIS)

    Vianna Filho, Alfredo Marques

    2016-01-01

    The maintenance of systems and equipment is a central question related to Production Engineering. Although systems are not fully reliable, it is often necessary to minimize the failure occurrence likelihood. The failures occurrences can have disastrous consequences during a plane flight or operation of a nuclear power plant. The elaboration of a maintenance plan has as objective the prevention and recovery from system failures, increasing reliability and reducing the cost of unplanned shutdowns. It is also important to consider the issues related to organizations safety, especially those dealing with dangerous technologies. The objective of this thesis is to propose a method for maintenance analysis of a nuclear research reactor, using a socio-technical approach, and focused on existing conditions in Brazil. The research reactor studied belongs to the federal government and it is located in the city of Rio de Janeiro. The specific objective of this thesis is to develop the availability analysis of one of the principal systems of the research reactor, the nuclear instrumentation system. In this analysis, were taken into account not only the technical aspects of the modules related to nuclear instrumentation system, but also the human and organizational factors that could affect the availability of the nuclear instrumentation system. The results showed the influence of these factors on the availability of the nuclear instrumentation system. (author)

  20. The use of instruments for gravity related research

    Science.gov (United States)

    van Loon, J. J. W.

    The first experiments using machines and instruments to manipulate gravity and thus learn about the impact of gravity onto living systems were performed by T A Knight in 1806 exactly 2 centuries ago What have we learned from these experiments and in particular what have we leaned about the use of instruments to reveal the impact of gravity and rotation onto plants and other living systems In this overview paper I will introduce the use of various instruments for gravity related research From water wheel to Random Positioning Machine RPM from clinostat to Free Fall Machine FFM and Rotating Wall Vessel RWV the usefulness and working principles of these microgravity simulators will be discussed We will discuss the question whether the RPM is a useful microgravity simulator and how to interpret experimental results This work is supported by NWO-ALW-SRON grant MG-057

  1. Instrumental variable methods in comparative safety and effectiveness research.

    Science.gov (United States)

    Brookhart, M Alan; Rassen, Jeremy A; Schneeweiss, Sebastian

    2010-06-01

    Instrumental variable (IV) methods have been proposed as a potential approach to the common problem of uncontrolled confounding in comparative studies of medical interventions, but IV methods are unfamiliar to many researchers. The goal of this article is to provide a non-technical, practical introduction to IV methods for comparative safety and effectiveness research. We outline the principles and basic assumptions necessary for valid IV estimation, discuss how to interpret the results of an IV study, provide a review of instruments that have been used in comparative effectiveness research, and suggest some minimal reporting standards for an IV analysis. Finally, we offer our perspective of the role of IV estimation vis-à-vis more traditional approaches based on statistical modeling of the exposure or outcome. We anticipate that IV methods will be often underpowered for drug safety studies of very rare outcomes, but may be potentially useful in studies of intended effects where uncontrolled confounding may be substantial.

  2. Radiance Research Particle Soot/Absorption Photometer Instrument Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Springston, S. R. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2016-03-01

    Radiance Research PSAPs as described in this Handbook are deployed in the second ARM Mobile Facility (AMF2) Aerosol Observing System (AOS), the third ARM Mobile Facility (AMF3) AOS, ENA AOS and Mobile Aerosol Observing System (MAOS)-A. An earlier version of the PSAP is currently operated in the ARM Aerial Facility and at SGP. The older SGP instrument is covered in a separate Handbook.

  3. ARM Climate Research Facility Quarterly Instrument Report Fourth Quarter: October 1–December 30, 2010

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2011-01-17

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following sections: (1) new instrumentation in the process of being acquired and deployed, (2) existing instrumentation and progress on improvements or upgrades, (3) proposed future instrumentation, and (4) Small Business Innovation Research instrument development.

  4. Atmospheric Radiation Measurement Climate Research Facility (ACRF Instrumentation Status: New, Current, and Future)

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2008-01-30

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following four sections: (1) new instrumentation in the process of being acquired and deployed, (2) existing instrumentation and progress on improvements or upgrades, (3) proposed future instrumentation, and (4) Small Business Innovation Research instrument development.

  5. Transient response of level instruments in a research reactor

    International Nuclear Information System (INIS)

    Cheng, Lap Y.

    1989-01-01

    A numerical model has been developed to simulate the dynamics of water level instruments in a research nuclear reactor. A bubble device, with helium gas as the working fluid, is used to monitor liquid level by sensing the static head pressure due to the height of liquid in the reactor vessel. A finite-difference model is constructed to study the transient response of the water level instruments to pressure perturbations. The field equations which describe the hydraulics of the helium gas in the bubbler device are arranged in the form of a tridiagonal matrix and the field variables are solved at each time step by the Thomas algorithm. Simulation results indicate that the dynamic response of the helium gas depends mainly on the volume and the inertia of the gas in the level instrument tubings. The anomalies in the simulated level indication are attributed to the inherent lag in the level instrument due to the hydraulics of the system. 1 ref., 5 figs

  6. Instrument development for materials science research at WNR

    International Nuclear Information System (INIS)

    Eckert, J.; Silver, R.N.; Soper, A.; Vergamini, P.J.; Goldstone, J.; Larson, A.; Seeger, P.A.; Yarnell, J.

    1980-01-01

    The neutron scattering program at the Los Alamos spallation neutron source is based on the operational WNR facility which provides up to 11 μA of 800 MeV protons to a target in pulse widths up to 8 μs at 120 Hz. The immediate goals of the program are: to gain experience with neutron instrumentation at spallation neutron sources; and to explore the scientific potential for condensed matter research at these sources. The proton storage ring (PSR) funded for construction will provide 100 μA in 0.27 μs pulses at 12 Hz, therefore greatly improving intensity, time-of-flight (TOF) resolution, and repetition rate. The initial emphasis, given limited manpower and resources, has been placed on developing a set of prototype instruments which are relatively easy to implement and which take advantage of the unique characteristics of the present WNR when compared with reactor neutron sources

  7. Human machine interface for research reactor instrumentation and control system

    International Nuclear Information System (INIS)

    Mohd Sabri Minhat; Mohd Idris Taib; Izhar Abu Hussin; Zareen Khan Abdul Jalil Khan; Nurfarhana Ayuni Joha

    2010-01-01

    Most present design of Human Machine Interface for Research Reactor Instrumentation and Control System is modular-based, comprise of several cabinets such as Reactor Protection System, Control Console, Information Console as well as Communication Console. The safety, engineering and human factor will be concerned for the design. Redundancy and separation of signal and power supply are the main factor for safety consideration. The design of Operator Interface absolutely takes consideration of human and environmental factors. Physical parameters, experiences, trainability and long-established habit patterns are very important for user interface, instead of the Aesthetic and Operator-Interface Geometry. Physical design for New Instrumentation and Control System of RTP are proposed base on the state-of- the-art Human Machine Interface design. (author)

  8. Cryogenic instrumentation needs in the controlled thermonuclear research program

    International Nuclear Information System (INIS)

    Walstrom, P.L.

    1976-01-01

    The magnet development effort for the controlled thermonuclear research program will require extensive testing of superconducting coils at various sizes from small-scale models to full-size prototypes. Extensive use of diagnostic instrumentation will be required and to make detailed comparisons of predicted and actual performance in magnet tests and to monitor the test facility for incipient failure modes. At later stages of the program, cryogenic instrumentation will be required to monitor magnet system performance in fusion power reactors. Measured quantities may include temperature, strain, deflection, coil resistance, helium coolant pressure and flow, current, voltages, etc. The test environment, which includes high magnetic fields (up to 8-10 T) and low temperature, makes many commercial measuring devices inoperative or at least inaccurate. In order to ensure reliable measurements, careful screening of commercial devices for performance in the test environment will be required. A survey of potentially applicable instrumentation is presented along with available information on operation in the test environment based on experimental data or on analysis of the physical characteristics of the device. Areas where further development work is needed are delineated

  9. Backfitting in Rossendorf research reactor control and instrumentation system

    International Nuclear Information System (INIS)

    Klebau, J.; Seidler, S.

    1985-01-01

    The paper generally describes a decentralized Hierarchical Information System (HIS) which has been developed for backfitting in Rossendorf Research Reactor (RFR) control and instrumentation system. The RFR was put into operation in 1957 and reconstructed from 2 MW up to a thermal power of 10 MW at the end of the sixties. Backfitting is planned by use of an advanced computerized control system for the next years. Main tasks of HIS are: Processmonitoring, online-disturbance analysis, technical diagnosis, direct digital control and use of a special industrial robot for discharging of irradiated materials out of the reactor. Experiences obtained by HIS during a testperiod will be presented. (author)

  10. The Portable Dynamic Fundus Instrument: Uses in telemedicine and research

    Science.gov (United States)

    Hunter, Norwood; Caputo, Michael; Billica, Roger; Taylor, Gerald; Gibson, C. Robert; Manuel, F. Keith; Mader, Thomas; Meehan, Richard

    1994-01-01

    For years ophthalmic photographs have been used to track the progression of many ocular diseases such as macular degeneration and glaucoma as well as the ocular manifestations of diabetes, hypertension, and hypoxia. In 1987 a project was initiated at the Johnson Space Center (JSC) to develop a means of monitoring retinal vascular caliber and intracranial pressure during space flight. To conduct telemedicine during space flight operations, retinal images would require real-time transmissions from space. Film-based images would not be useful during in-flight operations. Video technology is beneficial in flight because the images may be acquired, recorded, and transmitted to the ground for rapid computer digital image processing and analysis. The computer analysis techniques developed for this project detected vessel caliber changes as small as 3 percent. In the field of telemedicine, the Portable Dynamic Fundus Instrument demonstrates the concept and utility of a small, self-contained video funduscope. It was used to record retinal images during the Gulf War and to transmit retinal images from the Space Shuttle Columbia during STS-50. There are plans to utilize this device to provide a mobile ophthalmic screening service in rural Texas. In the fall of 1993 a medical team in Boulder, Colorado, will transmit real-time images of the retina during remote consultation and diagnosis. The research applications of this device include the capability of operating in remote locations or small, confined test areas. There has been interest shown utilizing retinal imaging during high-G centrifuge tests, high-altitude chamber tests, and aircraft flight tests. A new design plan has been developed to incorporate the video instrumentation into face-mounted goggle. This design would eliminate head restraint devices, thus allowing full maneuverability to the subjects. Further development of software programs will broaden the application of the Portable Dynamic Fundus Instrument in

  11. Instrumentation

    International Nuclear Information System (INIS)

    Prieur, G.; Nadi, M.; Hedjiedj, A.; Weber, S.

    1995-01-01

    This second chapter on instrumentation gives little general consideration on history and classification of instrumentation, and two specific states of the art. The first one concerns NMR (block diagram of instrumentation chain with details on the magnets, gradients, probes, reception unit). The first one concerns precision instrumentation (optical fiber gyro-meter and scanning electron microscope), and its data processing tools (programmability, VXI standard and its history). The chapter ends with future trends on smart sensors and Field Emission Displays. (D.L.). Refs., figs

  12. Research on Web-Based Networked Virtual Instrument System

    International Nuclear Information System (INIS)

    Tang, B P; Xu, C; He, Q Y; Lu, D

    2006-01-01

    The web-based networked virtual instrument (NVI) system is designed by using the object oriented methodology (OOM). The architecture of the NVI system consists of two major parts: client-web server interaction and instrument server-virtual instrument (VI) communication. The web server communicates with the instrument server and the clients connected to it over the Internet, and it handles identifying the user's name, managing the connection between the user and the instrument server, adding, removing and configuring VI's information. The instrument server handles setting the parameters of VI, confirming the condition of VI and saving the VI's condition information into the database. The NVI system is required to be a general-purpose measurement system that is easy to maintain, adapt and extend. Virtual instruments are connected to the instrument server and clients can remotely configure and operate these virtual instruments. An application of The NVI system is given in the end of the paper

  13. MRI-guided trephine biopsy and fine-needle aspiration in the diagnosis of bone lesions in low-field (0.23 T) MRI system using optical instrument tracking

    International Nuclear Information System (INIS)

    Blanco Sequeiros, Roberto; Klemola, Rauli; Ojala, Risto; Jyrkinen, Lasse; Tervonen, Osmo; Lappi-Blanco, Elisa; Soini, Ylermi

    2002-01-01

    The purpose of this study was to evaluate the feasibility of MRI-guided bone biopsy with optical instrument tracking and evaluate advantage of combined fine-needle aspiration (FNA) with trephine biopsy. Twenty trephine bone biopsies and 13 FNAs were performed under MRI and CT guidance in 14 patients. Informed consent was obtained from all patients. The evaluation of diagnostic accuracy was achieved by comparing the histopathological and cytological diagnosis with current or final diagnosis made during 6-month clinical follow-up. A 0.23-T open MRI scanner with interventional tools (Outlook Proview, Marconi Medical Systems, Cleveland, Ohio) was used. A surface coil was used. For trephine biopsy MRI-compatible bone biopsy set (Daum medical, Schwerin, Germany) was used. The FNA was performed with MRI compatible 20-G needle (Cook, Bloomington, Ind.). The diagnostic accuracy of MRI-guided trephine biopsy was 95%. The FNA sample diagnosis concurred with the histological in 54%. Our results show that MRI guidance in bone biopsies is accurate and safe. It is comparable to CT-guided or open biopsy. The role of combined FNA with bone biopsies remains controversial. (orig.)

  14. Modernization of reactor instrumentation for research reactors at Trombay

    International Nuclear Information System (INIS)

    Darbhe, M.D.; Chaudhuri, H.

    1989-01-01

    The three research reactors at Trombay, viz., Apsara, Cirus and Zerlina were commissioned in 1956, 1960 and 1961 respectively. The nuclear instrumentation designs were based on the vacuum tube technology, which was prevalent during those days. The effect of component obsolescence of critical components like vacuum tubes, magnetic amplifiers and sensitrol meter relays was strongly felt since early 1970s. Also, the failure rates of the units were observed to show an increasing trend due to ageing and lack of good quality indigenous spares. Hence it was proposed to replace the nuclear instrumentation units for the three reactors, with those employing modern, state of the art solid state devices, keeping indigenous content as high as practicable. The work started in 1977 with the preparations of specifications and the project was scheduled to be completed in 1981. The project was divided into two phases. The Phase I comprising of nuclear channels common to all reactors and Phase II consisting exclusively of regulating system units of Cirus. The salient stages of project progress and completion were: (i) Fabrication and testing of final design prototypes was completed by end of 1982. (ii) Commissioning of new units at Apsara was completed in January 1984. (iii) Commissioning of new units at Cirus was completed in September 1984. An account of experience in all these stages and problems encountered is given. (author). 6 figs

  15. THE INSTRUMENTAL CONCERTO AS OBJECT OF SCIENTIFIC RESEARCH

    Directory of Open Access Journals (Sweden)

    ANDRIEŞ VLADIMIR

    2015-03-01

    Full Text Available The instrumental concerto is one of the oldest genres of European instrumental music whose history began about three centuries ago and is continuing at present demonstrating an extraordinary variety of forms and diversity of variants of its treatment. Approaching the concerto genre the researchers try to establish the main features characteristic of this genre, to reveal its nature and to formulate a „pattern” or genetic canon of the concerto. In the article there is an analysis of the works of a lot of musicologists from different countries that are dedicated to the historical stylistic evolution of the concerto genre and to the study of the most relevant samples, from their origin (the 16th-17th centuries up to the present time. In this context, of special interest are the studies signed by A. Veinus, M. Roeder, M. Steinberg, S. Keefe, I. Grebneva, E. Dolinscaia and other musicologists. The article was written on the basis of the materials of the doctoral thesis „Concerto for Viola and Orchestra: Methods of Study” worked out under the supervision of the late scientist and university professor Vladimir Axionov.

  16. Engaging undergraduate students in hadron physics research and instrumentation

    Science.gov (United States)

    Horn, Tanja

    2017-09-01

    Nuclear physics research is fundamental to our understanding of the visible universe and at the same time intertwined with our daily life. Nuclear physics studies the origin and structure of the atomic nuclei in terms of their basic constituents, the quarks and gluons. Atoms and molecules would not exist without underlying quark-gluon interactions, which build nearly all the mass of the visible universe from an assembly of massless gluons and nearly-massless quarks. The study of hadron structure with electromagnetic probes through exclusive and semi-inclusive scattering experiments carried out at the 12 GeV Jefferson Laboratory plays an important role in this effort. In particular, planned precision measurements of pion and kaon form factors and longitudinal-transverse separated deep exclusive pion and kaon electroproduction cross sections to the highest momentum transfers achievable play an important role in understanding hadron structure and masses and provide essential constraints for 3D hadron imaging. While a growing fraction of nuclear physics research is carried out at large international laboratories, individual university research groups play critical roles in the success of that research. These include data analysis projects and the development of state-of-the-art instrumentation demanded by increasingly sophisticated experiments. These efforts are empowered by the creativity of university faculty, staff, postdocs, and provide students with unique hands-on experience. As an example, an aerogel Cherenkov detector enabling strangeness physics research in Hall C at Jefferson Lab was constructed at the Catholic University of America with the help of 16 undergraduate and high school students. The ''Conference Experience for Undergraduates'' (CEU) provides a venue for these students who have conducted research in nuclear physics. This presentation will present the experiences of one of the participants in the first years of the CEU, her current research program

  17. The OMERACT MRI in Arthritis Working Group - Update on Status and Future Research Priorities.

    Science.gov (United States)

    Østergaard, Mikkel; Bird, Paul; Gandjbakhch, Frédérique; Eshed, Iris; Haugen, Ida K; Haavardsholm, Espen A; Lillegraven, Siri; Foltz, Violaine; Glinatsi, Daniel; Peterfy, Charles; Ejbjerg, Bo; Bøyesen, Pernille; Mease, Philip J; Hermann, Kay-Geert; Emery, Paul; Genant, Harry K; Conaghan, Philip G

    2015-12-01

    To provide an update on the status and future research priorities of the Outcome Measures in Rheumatology (OMERACT) magnetic resonance imaging (MRI) in arthritis working group. A summary is provided of the activities of the group within rheumatoid arthritis (RA), psoriatic arthritis (PsA), and osteoarthritis (OA), and its research priorities. The OMERACT RA MRI score (RAMRIS) evaluating bone erosion, bone edema (osteitis), and synovitis is now the standard method of quantifying articular pathology in RA trials. Cartilage loss is another important part of joint damage, and at the OMERACT 12 conference, we provided longitudinal data demonstrating reliability and sensitivity to change of the RAMRIS JSN component score, supporting its use in future clinical trials. The MRI group has previously developed a PsA MRI score (PsAMRIS). At OMERACT 12, PsAMRIS was evaluated in a randomized placebo-controlled trial of patients with PsA, demonstrating the responsiveness and discriminatory ability of applying the PsAMRIS to hands and feet. A hand OA MRI score (HOAMRIS) was introduced at OMERACT 11, and has subsequently been further validated. At OMERACT 12, good cross-sectional interreader reliability, but variable reliability of change scores, were reported. Potential future research areas were identified at the MRI session at OMERACT 12 including assessment of tenosynovitis in RA and enthesitis in PsA and focusing on alternative MRI techniques. MRI has been further developed and validated as an outcome measure in RA, PsA, and OA. The group will continue its efforts to optimize the value of MRI as a robust biomarker in rheumatology clinical trials.

  18. Instrumental and ethical aspects of experimental research with animal models

    Directory of Open Access Journals (Sweden)

    Mirian Watanabe

    2014-02-01

    Full Text Available Experimental animal models offer possibilities of physiology knowledge, pathogenesis of disease and action of drugs that are directly related to quality nursing care. This integrative review describes the current state of the instrumental and ethical aspects of experimental research with animal models, including the main recommendations of ethics committees that focus on animal welfare and raises questions about the impact of their findings in nursing care. Data show that, in Brazil, the progress in ethics for the use of animals for scientific purposes was consolidated with Law No. 11.794/2008 establishing ethical procedures, attending health, genetic and experimental parameters. The application of ethics in handling of animals for scientific and educational purposes and obtaining consistent and quality data brings unquestionable contributions to the nurse, as they offer subsidies to relate pathophysiological mechanisms and the clinical aspect on the patient.

  19. Instrumentation

    International Nuclear Information System (INIS)

    Decreton, M.

    2002-01-01

    SCK-CEN's R and D programme on instrumentation involves the development of advanced instrumentation systems for nuclear applications as well as the assessment of the performance of these instruments in a radiation environment. Particular emphasis is on the use of optical fibres as umbilincal links of a remote handling unit for use during maintanance of a fusion reacor, studies on the radiation hardening of plasma diagnostic systems; investigations on new instrumentation for the future MYRRHA accelerator driven system; space applications related to radiation-hardened lenses; the development of new approaches for dose, temperature and strain measurements; the assessment of radiation-hardened sensors and motors for remote handling tasks and studies of dose measurement systems including the use of optical fibres. Progress and achievements in these areas for 2001 are described

  20. Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Decreton, M

    2002-04-01

    SCK-CEN's R and D programme on instrumentation involves the development of advanced instrumentation systems for nuclear applications as well as the assessment of the performance of these instruments in a radiation environment. Particular emphasis is on the use of optical fibres as umbilincal links of a remote handling unit for use during maintanance of a fusion reacor, studies on the radiation hardening of plasma diagnostic systems; investigations on new instrumentation for the future MYRRHA accelerator driven system; space applications related to radiation-hardened lenses; the development of new approaches for dose, temperature and strain measurements; the assessment of radiation-hardened sensors and motors for remote handling tasks and studies of dose measurement systems including the use of optical fibres. Progress and achievements in these areas for 2001 are described.

  1. Facilitating Research and Learning in Petrology and Geochemistry through Classroom Applications of Remotely Operable Research Instrumentation

    Science.gov (United States)

    Ryan, J. G.

    2012-12-01

    Bringing the use of cutting-edge research tools into student classroom experiences has long been a popular educational strategy in the geosciences and other STEM disciplines. The NSF CCLI and TUES programs have funded a large number of projects that placed research-grade instrumentation at educational institutions for instructional use and use in supporting undergraduate research activities. While student and faculty response to these activities has largely been positive, a range of challenges exist related to their educational effectiveness. Many of the obstacles these approaches have faced relate to "scaling up" of research mentoring experiences (e.g., providing training and time for use for an entire classroom of students, as opposed to one or two), and to time tradeoffs associated with providing technical training for effective instrument use versus course content coverage. The biggest challenge has often been simple logistics: a single instrument, housed in a different space, is difficult to integrate effectively into instructional activities. My CCLI-funded project sought primarily to knock down the logistical obstacles to research instrument use by taking advantage of remote instrument operation technologies, which allow the in-classroom use of networked analytical tools. Remote use of electron microprobe and SEM instruments of the Florida Center for Analytical Electron Microscopy (FCAEM) in Miami, FL was integrated into two geoscience courses at USF in Tampa, FL. Remote operation permitted the development of whole-class laboratory exercises to familiarize students with the tools, their function, and their capabilities; and it allowed students to collect high-quality chemical and image data on their own prepared samples in the classroom during laboratory periods. These activities improve student engagement in the course, appear to improve learning of key concepts in mineralogy and petrology, and have led to students pursuing independent research projects, as

  2. Instruments

    International Nuclear Information System (INIS)

    Buehrer, W.

    1996-01-01

    The present paper mediates a basic knowledge of the most commonly used experimental techniques. We discuss the principles and concepts necessary to understand what one is doing if one performs an experiment on a certain instrument. (author) 29 figs., 1 tab., refs

  3. Instrumentation for Basic Research in Communication and Hearing Protection Systems

    National Research Council Canada - National Science Library

    Ray, Laura

    2004-01-01

    .... The instrumentation provided by this grant consists of an Artificial Head Measurement System, a Low Frequency Acoustic Test Cell, a vibration isolation table, and digital signal processing equipment...

  4. Research and development of thermal-fluid measuring instrument

    International Nuclear Information System (INIS)

    Tuzla, K.; Chen, J.C.

    1991-01-01

    The goal of this program is to develop an instrument to measure the time-fraction of liquid contact in the transition and film boiling regimes for flow within a vertical tube. The work was carried out at Lehigh University between February 15, 1989 to February 15, 1991. The instrument to measure time-fraction of liquid contact was successfully developed and tested

  5. The Brazilian Portuguese Lexicon: An Instrument for Psycholinguistic Research.

    Science.gov (United States)

    Estivalet, Gustavo L; Meunier, Fanny

    2015-01-01

    In this article, we present the Brazilian Portuguese Lexicon, a new word-based corpus for psycholinguistic and computational linguistic research in Brazilian Portuguese. We describe the corpus development, the specific characteristics on the internet site and database for user access. We also perform distributional analyses of the corpus and comparisons to other current databases. Our main objective was to provide a large, reliable, and useful word-based corpus with a dynamic, easy-to-use, and intuitive interface with free internet access for word and word-criteria searches. We used the Núcleo Interinstitucional de Linguística Computacional's corpus as the basic data source and developed the Brazilian Portuguese Lexicon by deriving and adding metalinguistic and psycholinguistic information about Brazilian Portuguese words. We obtained a final corpus with more than 30 million word tokens, 215 thousand word types and 25 categories of information about each word. This corpus was made available on the internet via a free-access site with two search engines: a simple search and a complex search. The simple engine basically searches for a list of words, while the complex engine accepts all types of criteria in the corpus categories. The output result presents all entries found in the corpus with the criteria specified in the input search and can be downloaded as a.csv file. We created a module in the results that delivers basic statistics about each search. The Brazilian Portuguese Lexicon also provides a pseudoword engine and specific tools for linguistic and statistical analysis. Therefore, the Brazilian Portuguese Lexicon is a convenient instrument for stimulus search, selection, control, and manipulation in psycholinguistic experiments, as also it is a powerful database for computational linguistics research and language modeling related to lexicon distribution, functioning, and behavior.

  6. The Brazilian Portuguese Lexicon: An Instrument for Psycholinguistic Research

    Science.gov (United States)

    Estivalet, Gustavo L.; Meunier, Fanny

    2015-01-01

    In this article, we present the Brazilian Portuguese Lexicon, a new word-based corpus for psycholinguistic and computational linguistic research in Brazilian Portuguese. We describe the corpus development, the specific characteristics on the internet site and database for user access. We also perform distributional analyses of the corpus and comparisons to other current databases. Our main objective was to provide a large, reliable, and useful word-based corpus with a dynamic, easy-to-use, and intuitive interface with free internet access for word and word-criteria searches. We used the Núcleo Interinstitucional de Linguística Computacional’s corpus as the basic data source and developed the Brazilian Portuguese Lexicon by deriving and adding metalinguistic and psycholinguistic information about Brazilian Portuguese words. We obtained a final corpus with more than 30 million word tokens, 215 thousand word types and 25 categories of information about each word. This corpus was made available on the internet via a free-access site with two search engines: a simple search and a complex search. The simple engine basically searches for a list of words, while the complex engine accepts all types of criteria in the corpus categories. The output result presents all entries found in the corpus with the criteria specified in the input search and can be downloaded as a.csv file. We created a module in the results that delivers basic statistics about each search. The Brazilian Portuguese Lexicon also provides a pseudoword engine and specific tools for linguistic and statistical analysis. Therefore, the Brazilian Portuguese Lexicon is a convenient instrument for stimulus search, selection, control, and manipulation in psycholinguistic experiments, as also it is a powerful database for computational linguistics research and language modeling related to lexicon distribution, functioning, and behavior. PMID:26630138

  7. Instrumentation

    International Nuclear Information System (INIS)

    Muehllehner, G.; Colsher, J.G.

    1982-01-01

    This chapter reviews the parameters which are important to positron-imaging instruments. It summarizes the options which various groups have explored in designing tomographs and the methods which have been developed to overcome some of the limitations inherent in the technique as well as in present instruments. The chapter is not presented as a defense of positron imaging versus single-photon or other imaging modality, neither does it contain a description of various existing instruments, but rather stresses their common properties and problems. Design parameters which are considered are resolution, sampling requirements, sensitivity, methods of eliminating scattered radiation, random coincidences and attenuation. The implementation of these parameters is considered, with special reference to sampling, choice of detector material, detector ring diameter and shielding and variations in point spread function. Quantitation problems discussed are normalization, and attenuation and random corrections. Present developments mentioned are noise reduction through time-of-flight-assisted tomography and signal to noise improvements through high intrinsic resolution. Extensive bibliography. (U.K.)

  8. MIPAS: an instrument for atmospheric and climate research

    Directory of Open Access Journals (Sweden)

    H. Fischer

    2008-04-01

    Full Text Available MIPAS, the Michelson Interferometer for Passive Atmospheric Sounding, is a mid-infrared emission spectrometer which is part of the core payload of ENVISAT. It is a limb sounder, i.e. it scans across the horizon detecting atmospheric spectral radiances which are inverted to vertical temperature, trace species and cloud distributions. These data can be used for scientific investigations in various research fields including dynamics and chemistry in the altitude region between upper troposphere and lower thermosphere.

    The instrument is a well calibrated and characterized Fourier transform spectrometer which is able to detect many trace constituents simultaneously. The different concepts of retrieval methods are described including multi-target and two-dimensional retrievals. Operationally generated data sets consist of temperature, H2O, O3, CH4, N2O, HNO3, and NO2 profiles. Measurement errors are investigated in detail and random and systematic errors are specified. The results are validated by independent instrumentation which has been operated at ground stations or aboard balloon gondolas and aircraft. Intercomparisons of MIPAS measurements with other satellite data have been carried out, too. As a result, it has been proven that the MIPAS data are of good quality.

    MIPAS can be operated in different measurement modes in order to optimize the scientific output. Due to the wealth of information in the MIPAS spectra, many scientific results have already been published. They include intercomparisons of temperature distributions with ECMWF data, the derivation of the whole NOy family, the study of atmospheric processes during the Antarctic vortex split in September~2002, the determination of properties of Polar Stratospheric Clouds, the downward transport of NOx in the middle atmosphere, the stratosphere-troposphere exchange, the influence of

  9. Research and realization of signal simulation on virtual instrument

    Science.gov (United States)

    Zhao, Qi; He, Wenting; Guan, Xiumei

    2010-02-01

    In the engineering project, arbitrary waveform generator controlled by software interface is needed by simulation and test. This article discussed the program using the SCPI (Standard Commands For Programmable Instruments) protocol and the VISA (Virtual Instrument System Architecture) library to control the Agilent signal generator (Agilent N5182A) by instrument communication over the LAN interface. The program can conduct several signal generations such as CW (continuous wave), AM (amplitude modulation), FM (frequency modulation), ΦM (phase modulation), Sweep. As the result, the program system has good operability and portability.

  10. Benchtop-NMR and MRI--a new analytical tool in drug delivery research.

    Science.gov (United States)

    Metz, Hendrik; Mäder, Karsten

    2008-12-08

    During the last years, NMR spectroscopy and NMR imaging (magnetic resonance imaging, MRI) have been increasingly used to monitor drug delivery systems in vitro and in vivo. However, high installation and running costs of the commonly used superconducting magnet technology limits the application range and prevents the further spread of this non-invasive technology. Benchtop-NMR (BT-NMR) relaxometry uses permanent magnets and is much less cost intensive. BT-NMR relaxometry is commonly used in the food and chemical industry, but so far scarcely used in the pharmaceutical field. The paper shows on several examples that the application field of BT-NMR relaxometry can be extended into the field of drug delivery, including the characterisation of emulsions and lipid ingredients (e.g. the amount and physicochemical state of the lipid) and the monitoring of adsorption characteristics (e.g. oil binding of porous ingredients). The most exciting possibilities of BT-NMR technology are linked with the new development of BT-instruments with imaging capability. BT-MRI examples on the monitoring of hydration and swelling of HPMC-based monolayer and double-layer tablets are shown. BT-MRI opens new MRI opportunities for the non-invasive monitoring of drug delivery processes.

  11. Overview of the ultrasonic instrumentation research in the MYRRHA project

    Energy Technology Data Exchange (ETDEWEB)

    Dierckx, M.; Leysen, W.; Van Dyck, D. [Belgian Nuclear Research Center SCK.CEN (Belgium)

    2015-07-01

    The Belgian Nuclear Research Centre SCK.CEN is in the process of developing MYRRHA, a new generation IV fast flux research reactor to replace the aging BR2. MYRRHA is conceptualized as an accelerator driven system cooled with lead bismuth eutectic mixture (LBE). As LBE is opaque to visual light, ultrasonic measurement techniques are employed as the main technology to provide feedback where needed. This paper we will give an overview of the R and D at SCK.CEN with respect to ultrasonic instrumentation in heavy liquid metals. High temperature ultrasonic transducers are deployed into the reactor to generate and receive the required ultrasonic signals. The ultrasonic waves are generated and sensed by means of a piezo-electric disc at the heart of the transducer. The acoustic properties of commonly used piezo-electric materials match rather well with the acoustic properties of heavy liquid metals, simplifying the design and construction of high bandwidth ultrasonic transducers for use in heavy liquid metals. The ultrasonic transducers will operate in a liquid metal environment, where radiation and high temperature limit the choice of materials for construction. Moreover, the high surface tension of the liquid metal hinders proper wetting of the transducer, required for optimal transmission and reception of the ultrasonic waves. In a first part of the paper, we will discuss the effect of these parameters on the performance of the overall ultrasonic system. In the second part of the paper, past, present and future ultrasonic experiments in LBE will be reviewed. We will show the results of an experiment where a transducer is scanned near the free surface of an LBE pool to render ultrasonic images of objects submerged in the heavy liquid metal. Additionally, the preliminary results of an ongoing experiment that measures the evolution of LBE wetting on different types of metals and various surface conditions will be reported. The evolution of wetting is an important

  12. MRI-guided periradicular nerve root infiltration therapy in low-field (0.23-T) MRI system using optical instrument tracking

    International Nuclear Information System (INIS)

    Sequeiros, Roberto Blanco; Ojala, Risto O.; Klemola, Rauli; Jyrkinen, Lasse; Tervonen, Osmo A.; Vaara, Teuvo J.

    2002-01-01

    The purpose of this study was to evaluate the feasibility of the MRI-guided periradicular nerve root infiltration therapy. Sixty-seven nerve root infiltrations under MRI guidance were done for 61 patients suffering from lumbosacral radicular pain. Informed consent was acquired from all patients. A 0.23-T open-MRI scanner with interventional tools (Outlook Proview, Philips Medical Systems, MR Technologies, Finland) was used. A surface coil was used in all cases. Nerve root infiltration was performed with MRI-compatible 20-G needle (Chiba type MReye, Cook, Bloomington, Ind.; or Manan type, MD Tech, Florida). The evaluation of clinical outcome was achieved with 6 months of clinical follow-up and questionnaire. The effect of nerve root infiltration to the radicular pain was graded: 1=good to excellent, i.e., no pain or not disturbing pain allowing normal physical activity at 3 months from the procedure; 2=temporary, i.e., temporary relief of pain; 3=no relief of pain; and 4=worsening of pain. As an adjunct to MRI-guided positioning of the needle the correct needle localization by the nerve root was confirmed with saline injection to nerve root channel and single-shot fast spin echo (SSFSE) imaging. The MRI guidance allowed adequate needle positioning in all but 1 case (98.5%). This failure was caused by degeneration-induced changes in anatomy. Of patients, 51.5% had good to excellent effect with regard to radicular pain from the procedure, 22.7% had temporary relief, 21.2% had no effect, and in 4.5% the pain worsened. Our results show that MRI guidance is accurate and safe in performing nerve root infiltration at lumbosacral area. The results of radicular pain relief from nerve root infiltration are comparable to CT or fluoroscopy studies on the subject. (orig.)

  13. Translation of an instrument. The US-Nordic Family Dynamics Nursing Research Project.

    Science.gov (United States)

    White, M; Elander, G

    1992-01-01

    Translation of a research instrument questionnaire from English to another language is analyzed in relation to principles involved, procedures followed, and problems confronted by nurse researchers from the US-Nordic Family Dynamics Nursing Research Project. Of paramount importance in translation are translation equivalency, congruent value orientation, and careful use of colloquialisms. It is important to recognize that copyright guidelines apply in the translation of an instrument. Approaches to solving instrument translation problems are discussed.

  14. [Research on medical instrument information integration technology based on IHE PCD].

    Science.gov (United States)

    Zheng, Jianli; Liao, Yun; Yang, Yongyong

    2014-06-01

    Integrating medical instruments with medical information systems becomes more and more important in healthcare industry. To make medical instruments without standard communication interface possess the capability of interoperating and sharing information with medical information systems, we developed a medical instrument integration gateway based on Integrating the Healthcare Enterprise Patient Care Device (IHE PCD) integration profiles in this research. The core component is an integration engine which is implemented according to integration profiles and Health Level Seven (HL7) messages defined in IHE PCD. Working with instrument specific Javascripts, the engine transforms medical instrument data into HL7 ORU message. This research enables medical instruments to interoperate and exchange medical data with information systems in a standardized way, and is valuable for medical instrument integration, especially for traditional instruments.

  15. The OMERACT MRI in Arthritis Working Group - Update on Status and Future Research Priorities

    DEFF Research Database (Denmark)

    Østergaard, Mikkel; Bird, Paul; Gandjbakhch, Frédérique

    2015-01-01

    OBJECTIVE: To provide an update on the status and future research priorities of the Outcome Measures in Rheumatology (OMERACT) magnetic resonance imaging (MRI) in arthritis working group. METHODS: A summary is provided of the activities of the group within rheumatoid arthritis (RA), psoriatic...

  16. Incidental findings in healthy control research subjects using whole-body MRI

    International Nuclear Information System (INIS)

    Morin, S.H.X.; Cobbold, J.F.L.; Lim, A.K.P.; Eliahoo, J.; Thomas, E.L.; Mehta, S.R.; Durighel, G.; Fitzpatrick, J.; Bell, J.D.

    2009-01-01

    Aim: Magnetic resonance imaging (MRI) is a powerful clinical tool used increasingly in the research setting. We aimed to assess the prevalence of incidental findings in a sequential cohort of healthy volunteers undergoing whole-body MRI as part of a normal control database for imaging research studies. Materials and methods: 148 healthy volunteers (median age 36 years, range 21-69 years; 63.5% males, 36.5% females) were enrolled into a prospective observational study at a single hospital-based MRI research unit in London, UK. Individuals with a clinical illness, treated or under investigation were excluded from the study. Results: 43 (29.1%) scans were abnormal with a total of 49 abnormalities detected. Of these, 20 abnormalities in 19 patients (12.8%) were of clinical significance. The prevalence of incidental findings increased significantly with both increasing age and body mass index (BMI). Obese subjects had a fivefold greater risk of having an incidental abnormality on MRI (OR 5.4, CI 2.1-14.0). Conclusions: This study showed that more than one quarter of healthy volunteers have MR-demonstrable abnormalities. There was an increased risk of such findings in obese patients. This has ethical and financial implications for future imaging research, particularly with respect to informed consent and follow-up of those with abnormalities detected during the course of imaging studies.

  17. Scientific Applications of Optical Instruments to Materials Research

    Science.gov (United States)

    Witherow, William K.

    1997-01-01

    Microgravity is a unique environment for materials and biotechnology processing. Microgravity minimizes or eliminates some of the effects that occur in one g. This can lead to the production of new materials or crystal structures. It is important to understand the processes that create these new materials. Thus, experiments are designed so that optical data collection can take place during the formation of the material. This presentation will discuss scientific application of optical instruments at MSFC. These instruments include a near-field scanning optical microscope, a miniaturized holographic system, and a phase-shifting interferometer.

  18. FY09 Advanced Instrumentation and Active Interrogation Research for Safeguards

    International Nuclear Information System (INIS)

    Chichester, D.L.; Pozzi, S.A.; Seabury, E.H.; Dolan, J.L.; Flaska, M.; Johnson, J.T.; Watson, S.M.; Wharton, J.

    2009-01-01

    Multiple small-scale projects have been undertaken to investigate advanced instrumentation solutions for safeguard measurement challenges associated with advanced fuel cycle facilities and next-generation fuel reprocessing installations. These activities are in support of the U.S. Department of Energy's Fuel Cycle Research and Development program and its Materials Protection, Accounting, and Control for Transmutation (MPACT) campaign. (1) Work was performed in a collaboration with the University of Michigan (Prof. Sara Pozzi, co-PI) to investigate the use of liquid-scintillator radiation detectors for assaying mixed-oxide (MOX) fuel, to characterize its composition and to develop advanced digital pulse-shape discrimination algorithms for performing time-correlation measurements in the MOX fuel environment. This work included both simulations and experiments and has shown that these techniques may provide a valuable approach for use within advanced safeguard measurement scenarios. (2) Work was conducted in a collaboration with Oak Ridge National Laboratory (Dr. Paul Hausladen, co-PI) to evaluate the strengths and weaknesses of the fast-neutron coded-aperture imaging technique for locating and characterizing fissile material, and as a tool for performing hold-up measurements in fissile material handling facilities. This work involved experiments at Idaho National Laboratory, using MOX fuel and uranium metal, in both passive and active interrogation configurations. A complete analysis has not yet been completed but preliminary results suggest several potential uses for the fast neutron imaging technique. (3) Work was carried out to identify measurement approaches for determining nitric acid concentration in the range of 1-4 M and beyond. This work included laboratory measurements to investigate the suitability of prompt-gamma neutron activation analysis for this measurement and product reviews of other commercial solutions. Ultrasonic density analysis appears to be

  19. Ionosphere research with a HF/MF cubesat radio instrument

    Science.gov (United States)

    Kallio, Esa; Aikio, Anita; Alho, Markku; Fontell, Mathias; Harri, Ari-Matti; Kauristie, Kirsti; Kestilä, Antti; Koskimaa, Petri; Mäkelä, Jakke; Mäkelä, Miika; Turunen, Esa; Vanhamäki, Heikki; Verronen, Pekka

    2017-04-01

    New technology provides new possibilities to study geospace and 3D ionosphere by using spacecraft and computer simulations. A type of nanosatellites, CubeSats, provide a cost effective possibility to provide in-situ measurements in the ionosphere. Moreover, combined CubeSat observations with ground-based observations gives a new view on auroras and associated electromagnetic phenomena. Especially joint and active CubeSat - ground based observation campaigns enable the possibility of studying the 3D structure of the ionosphere. Furthermore using several CubeSats to form satellite constellations enables much higher temporal resolution. At the same time, increasing computation capacity has made it possible to perform simulations where properties of the ionosphere, such as propagation of the electromagnetic waves in the medium frequency, MF (0.3-3 MHz) and high frequency, HF (3-30 MHz), ranges is based on a 3D ionospheric model and on first-principles modelling. Electromagnetic waves at those frequencies are strongly affected by ionospheric electrons and, consequently, those frequencies can be used for studying the plasma. On the other hand, even if the ionosphere originally enables long-range telecommunication at MF and HF frequencies, the frequent occurrence of spatiotemporal variations in the ionosphere disturbs communication channels, especially at high latitudes. Therefore, study of the MF and HF waves in the ionosphere has both a strong science and technology interests. We introduce recently developed simulation models as well as measuring principles and techniques to investigate the arctic ionosphere by a polar orbiting CubeSat whose novel AM radio instrument measures HF and MF waves. The cubesat, which contains also a white light aurora camera, is planned to be launched in late 2017 (http://www.suomi100satelliitti.fi/eng). The new models are (1) a 3D ray tracing model and (2) a 3D full kinetic electromagnetic simulation. We also introduce how combining of the

  20. Nuclear instrumentation for research reactors; Instrumentacion nuclear para reactores nucleares de investigacion

    Energy Technology Data Exchange (ETDEWEB)

    Hofer, Carlos G.; Pita, Antonio; Verrastro, Claudio A.; Maino, Eduardo J. [Comision Nacional de Energia Atomica, Buenos Aires (Argentina). Unidad de Actividades de Reactores y Centrales Nucleares. Sector Instrumentacion y Control

    1997-10-01

    The nuclear instrumentation for research reactors in Argentina was developed in 70`. A gradual modernization of all the nuclear instrumentation is planned. It includes start-up and power range instrumentation, as well as field monitors, clamp, scram and rod movement control logic. The new instrumentation is linked to a computer network, based on real time operating system for data acquisition, display and logging. This paper describes the modules and whole system aspects. (author). 2 refs.

  1. Choosing Assessment Instruments for Bulimia Practice and Outcome Research

    Science.gov (United States)

    Sandberg, Katie; Erford, Bradley T.

    2013-01-01

    Six commonly used instruments for assessment of eating disorders were analyzed. Effect size results from Erford et al.'s (2013) meta-analysis for the treatment of bulimia nervosa were used to compare each scale's ability to measure treatment outcomes for bulimia nervosa. Effect size comparisons indicated higher overall effect sizes using the…

  2. Two-phase flow instrumentation research at RPI

    International Nuclear Information System (INIS)

    Lahey, R.T. Jr.; Krycuk, G.

    1979-01-01

    Novel instrumentation for the measurement of void fraction and phase velocity was developed. An optical digital interferometer and a dual beam x-ray equipment were designed for detection of voids. Pitot tube measurements were made to understand two-phase flow phenomena in liquid phase velocity

  3. Software Defined Radio (SDR and Direct Digital Synthesizer (DDS for NMR/MRI Instruments at Low-Field

    Directory of Open Access Journals (Sweden)

    Aktham Asfour

    2013-11-01

    Full Text Available A proof-of-concept of the use of a fully digital radiofrequency (RF electronics for the design of dedicated Nuclear Magnetic Resonance (NMR systems at low-field (0.1 T is presented. This digital electronics is based on the use of three key elements: a Direct Digital Synthesizer (DDS for pulse generation, a Software Defined Radio (SDR for a digital receiving of NMR signals and a Digital Signal Processor (DSP for system control and for the generation of the gradient signals (pulse programmer. The SDR includes a direct analog-to-digital conversion and a Digital Down Conversion (digital quadrature demodulation, decimation filtering, processing gain…. The various aspects of the concept and of the realization are addressed with some details. These include both hardware design and software considerations. One of the underlying ideas is to enable such NMR systems to “enjoy” from existing advanced technology that have been realized in other research areas, especially in telecommunication domain. Another goal is to make these systems easy to build and replicate so as to help research groups in realizing dedicated NMR desktops for a large palette of new applications. We also would like to give readers an idea of the current trends in this field. The performances of the developed electronics are discussed throughout the paper. First FID (Free Induction Decay signals are also presented. Some development perspectives of our work in the area of low-field NMR/MRI will be finally addressed.

  4. Software Defined Radio (SDR) and Direct Digital Synthesizer (DDS) for NMR/MRI Instruments at Low-Field

    Science.gov (United States)

    Asfour, Aktham; Raoof, Kosai; Yonnet, Jean-Paul

    2013-01-01

    A proof-of-concept of the use of a fully digital radiofrequency (RF) electronics for the design of dedicated Nuclear Magnetic Resonance (NMR) systems at low-field (0.1 T) is presented. This digital electronics is based on the use of three key elements: a Direct Digital Synthesizer (DDS) for pulse generation, a Software Defined Radio (SDR) for a digital receiving of NMR signals and a Digital Signal Processor (DSP) for system control and for the generation of the gradient signals (pulse programmer). The SDR includes a direct analog-to-digital conversion and a Digital Down Conversion (digital quadrature demodulation, decimation filtering, processing gain…). The various aspects of the concept and of the realization are addressed with some details. These include both hardware design and software considerations. One of the underlying ideas is to enable such NMR systems to “enjoy” from existing advanced technology that have been realized in other research areas, especially in telecommunication domain. Another goal is to make these systems easy to build and replicate so as to help research groups in realizing dedicated NMR desktops for a large palette of new applications. We also would like to give readers an idea of the current trends in this field. The performances of the developed electronics are discussed throughout the paper. First FID (Free Induction Decay) signals are also presented. Some development perspectives of our work in the area of low-field NMR/MRI will be finally addressed. PMID:24287540

  5. Econometrics in outcomes research: the use of instrumental variables.

    Science.gov (United States)

    Newhouse, J P; McClellan, M

    1998-01-01

    We describe an econometric technique, instrumental variables, that can be useful in estimating the effectiveness of clinical treatments in situations when a controlled trial has not or cannot be done. This technique relies upon the existence of one or more variables that induce substantial variation in the treatment variable but have no direct effect on the outcome variable of interest. We illustrate the use of the technique with an application to aggressive treatment of acute myocardial infarction in the elderly.

  6. NIRS report of utilization of MRI machine for research. Results in 2003

    International Nuclear Information System (INIS)

    2006-04-01

    The report is an achievement of cooperative research and development by private and official facilities of the National Institute of Radiological Sciences (NIRS) MRI machine, and its applied and medical uses in 2003. Contained are the reports on the magnet (1 topic), antennae (4), physical mensurations (5), basic biological researches (6), basic studies on human body (6) and clinical studies (13), which are finally summarized in the list of the personnel, event calendar and published scientific papers. The basic studies by the MRI involve those of the brain damage by heavy particle irradiation, pediatric surgical diseases by MR-microscopy, implanted tumor volumetry in the rat, biodistribution of BPA- gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) for neutron capture therapy, ultra-high speed microscopic MRI measurement of microcirculation in the tumor, micro-imaging of human eye, hepatic glycogen content by MRS, flow analysis of cerebrospinal fluid, autopsy imaging system, numerical phantom of human body and so on. Clinical studies involve those of the drug metabolism and disposition, efficacy evaluation of radiotherapy, PET-CT-MRI image, schizophrenia, GSH detection, MP4A-PET image standardization, intracranial lymph systems, brain function, GSH in schizophrenia, obstructive hypertrophic cardiomyopathy, cholangiography, glycosaminoglycan in cartilage and high-speed imaging of prostate cancer by sensitivity encoding. (T.I.)

  7. Incidental findings in youths volunteering for brain MRI research.

    Science.gov (United States)

    Gur, R E; Kaltman, D; Melhem, E R; Ruparel, K; Prabhakaran, K; Riley, M; Yodh, E; Hakonarson, H; Satterthwaite, T; Gur, R C

    2013-10-01

    MRIs are obtained in research in healthy and clinical populations, and incidental findings have been reported. Most studies have examined adults with variability in parameters of image acquisition and clinical measures available. We conducted a prospective study of youths and documented the frequency and concomitants of incidental findings. Youths (n = 1400) with an age range from 8-23 years were imaged on the same 3T scanner, with a standard acquisition protocol providing 1.0 mm(3) isotropic resolution of anatomic scans. All scans were reviewed by an experienced board-certified neuroradiologist and were categorized into 3 groups: 1) normal: no incidental findings; 2) coincidental: incidental finding(s) were noted, further reviewed with an experienced pediatric neuroradiologist, but were of no clinical significance; 3) incidental findings that on further review were considered to have potential clinical significance and participants were referred for appropriate clinical follow-up. Overall, 148 incidental findings (10.6% of sample) were noted, and of these, 12 required clinical follow-up. Incidental findings were not related to age. However, whites had a higher incidence of pineal cysts, and males had a higher incidence of cavum septum pellucidum, which was associated with psychosis-related symptoms. Incidental findings, moderated by race and sex, occur in approximately one-tenth of participants volunteering for pediatric research, with few requiring follow-up. The incidence supports a 2-tiered approach of neuroradiologic reading and clinical input to determine the potential significance of incidental findings detected on research MR imaging scans.

  8. Adaptation of a nursing home culture change research instrument for frontline staff quality improvement use.

    Science.gov (United States)

    Hartmann, Christine W; Palmer, Jennifer A; Mills, Whitney L; Pimentel, Camilla B; Allen, Rebecca S; Wewiorski, Nancy J; Dillon, Kristen R; Snow, A Lynn

    2017-08-01

    Enhanced interpersonal relationships and meaningful resident engagement in daily life are central to nursing home cultural transformation, yet these critical components of person-centered care may be difficult for frontline staff to measure using traditional research instruments. To address the need for easy-to-use instruments to help nursing home staff members evaluate and improve person-centered care, the psychometric method of cognitive-based interviewing was used to adapt a structured observation instrument originally developed for researchers and nursing home surveyors. Twenty-eight staff members from 2 Veterans Health Administration (VHA) nursing homes participated in 1 of 3 rounds of cognitive-based interviews, using the instrument in real-life situations. Modifications to the original instrument were guided by a cognitive processing model of instrument refinement. Following 2 rounds of cognitive interviews, pretesting of the revised instrument, and another round of cognitive interviews, the resulting set of 3 short instruments mirrored the concepts of the original longer instrument but were significantly easier for frontline staff to understand and use. Final results indicated frontline staff found the revised instruments feasible to use and clinically relevant in measuring and improving the lived experience of a changing culture. This article provides a framework for developing or adapting other measurement tools for frontline culture change efforts in nursing homes, in addition to reporting on a practical set of instruments to measure aspects of person-centered care. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  9. NIRS report of utilization of MRI machine for research. Results in 2004

    International Nuclear Information System (INIS)

    2007-04-01

    The report is an achievement of cooperative research and development by private and official facilities of the National Institute of Radiological Sciences (NIRS) MRI machine, and its applied and medical uses in 2004. Contained are the reports on the magnet (1 topic), RF coils (6), basic studies on measurements (4), biological studies on measurements (4) and clinical studies on measurements (18), which are finally summarized in the list of the personnel, event calendar and published scientific papers. The basic studies by the MRI involve those of metabolism and molecular transport measurements using MRI contrast agents, macro-analysis and micro-analysis of cerebral blood flow by CFD, samples for radiation dose measurements using polymer gel materials and the MRS method for quantification of substances in the body. Biological studies involve those of the brain damage by heavy particle irradiation, pediatric surgical diseases by MR-microscopy, PET data analysis of the monkey taking MPTP and multiple sclerosis mice. Clinical studies involve those of blood vessel coupling of cerebral nerve, micro-imaging of human eye, hepatic glycogen content by MRS, autopsy imaging, numerical phantom of human body, PET-CT-MRI image, schizophrenia, GSH detection, MP4A-PET image standardization, MR imaging of perivascular space, brain function, GSH in schizophrenia, occlusive arterial disease of lower extremity, cholangiography, glycosaminoglycan in cartilage, MR imaging of wrist joint, high-speed imaging of prostate cancer by sensitivity encoding and volumetry of rats' tissues. (J.P.N.)

  10. Research in radiation monitoring survey instrumentation. Final report

    International Nuclear Information System (INIS)

    Blalock, T.V.; Kennedy, E.J.; Phillips, R.G.; Walker, E.W. Jr.

    1978-01-01

    Two low-power solid-state prototype readout units were developed, an LED display and a LCD display. This display output was in a bar-graph format, covering four-decades of information, with 10-segments per decade. The displays accept a frequency input, which is standardly available from several portable radiation-survey instruments. Both readout units will operate on two D-cell batteries (3.0 Volt), with a typical current drain requirement of 0.3 MA for the LED display and 30μA for the LCD display. A wide-range electrometer circuit was also developed. The circuit covers an input current range from 10 -13 A to 10 -8 A. The output signal is a pulse whose frequency is directly proportional to input current. The circuit requires no high-megohm resistors, and is autoranging. Several candidate input amplifiers were analyzed and evaluated for use with the electrometer circuit

  11. The Instrumental Value of Conceptual Frameworks in Educational Technology Research

    Science.gov (United States)

    Antonenko, Pavlo D.

    2015-01-01

    Scholars from diverse fields and research traditions agree that the conceptual framework is a critically important component of disciplined inquiry. Yet, there is a pronounced lack of shared understanding regarding the definition and functions of conceptual frameworks, which impedes our ability to design effective research and mentor novice…

  12. Food-related lifestyles in Singapore: Testing a Western European research instrument in Southeast Asia

    DEFF Research Database (Denmark)

    Askegaard, Søren; Brunsø, Karen; Crippen, Kaye

    The food-realaed life style instrument developed by the MAPP research group has, up till now, been applied mainly in the context of European cultures. The purpose of the present study is to apply the food-related life style instrument in a new and different cultural setting, to compare results, a...

  13. Serendipity: Genesis of the Electrochemical Instrumentation at Princeton Applied Research Corporation

    Science.gov (United States)

    Flato, J. B.

    2007-01-01

    Princeton Applied Research Corporation (PAR) was a small electronic instrument company in early 1960s but once they entered electrochemistry they were very successful. Since then they have developed and designed successful instruments with their tremendous knowledge and have made great contribution to the field of analytical chemistry.

  14. Food-related life styles in Singapore: Testing a Western European research instrument in Southeast Asia

    DEFF Research Database (Denmark)

    Askegaard, Søren; Brunsø, Karen; Crippen, Kaye

    The food-related life style instrument developed by the MAPP research group has, up til now, been applied mainly in the context of European cultures. The purpose of the present study is to apply the food-related life style instrument in a new and very different cultural setting, to compare results......, and to interpret similarities and differences found. For this purpose, data have been collected in Singaporean families using the food-related life style instrument. A total of 89 questionnaires form the basis of the analysis. First, the cross-cultural validity of the instrument is tested, and secondly...

  15. Military Medical Research in Support of National Instruments of Power

    Science.gov (United States)

    2009-03-26

    diseases. Military sponsored research in the U.S. and abroad has produced antibiotic cures for typhoid and scrub typhus, new anti-malarial drugs, and...ARV drugs to Kenyan tea plantation workers has directly resulted in the reduction of absenteeism , maintenance of highly developed skill sets

  16. Leadership for the Nineties: Development of Training and Research Instruments

    Science.gov (United States)

    1990-07-01

    1980). The will to fight. In S. C. Sarkesian (Ed.), Combat effectiveness: Cohesion, stress and the volunteer military. (pp. 186-212). Headquarters...Institute for the Bahavioral and Social Sciences. Oliver, L. W. (1988a). The relationship of group cohesion to group performance: A research integration...Sarkesian (Ed.), Combat effectiveness: Cohesion, stress and the volunteer military: Vol. 9 (pp. 57-93). Beverly Hills, CA: Sage Publications. Sterling, B.S

  17. The rhesus measurement system: A new instrument for space research

    Science.gov (United States)

    Schonfeld, Julie E.; Hines, John W.

    1993-01-01

    The Rhesus Research Facility (RRF) is a research environment designed to study the effects of microgravity using rhesus primates as human surrogates. This experimental model allows investigators to study numerous aspects of microgravity exposure without compromising crew member activities. Currently, the RRF is slated for two missions to collect its data, the first mission is SLS-3, due to fly in late 1995. The RRF is a joint effort between the United States and France. The science and hardware portions of the project are being shared between the National Aeronautics and Space Administration (NASA) and France's Centre National D'Etudes Spatiales (CNES). The RRF is composed of many different subsystems in order to acquire data, provide life support, environmental enrichment, computer facilities and measurement capabilities for two rhesus primates aboard a nominal sixteen day mission. One of these subsystems is the Rhesus Measurement System (RMS). The RMS is designed to obtain in-flight physiological measurements from sensors interfaced with the subject. The RMS will acquire, preprocess, and transfer the physiologic data to the Flight Data System (FDS) for relay to the ground during flight. The measurements which will be taken by the RMS during the first flight will be respiration, measured at two different sites; electromyogram (EMG) at three different sites; electroencephalogram (EEG); electrocardiogram (ECG); and body temperature. These measurements taken by the RMS will assist the research team in meeting the science objectives of the RRF project.

  18. Human factors research plan for instrument procedures : FY12 version 1.1

    Science.gov (United States)

    2012-06-19

    This research will support the development of instrument procedures for performance-based navigation (PBN) operations. These procedures include, but are not limited to, area navigation (RNAV) and required navigation performance (RNP) operations. The ...

  19. Using Psycho-Physiological Interaction Analysis with fMRI-Data in IS Research

    DEFF Research Database (Denmark)

    Hubert, Marco; Linzmajer, Marc; Riedl, René

    2017-01-01

    The integration of neuroscientific methods in Information Systems (IS) research to better understand how the brain interacts with IS-relevant context has gained in importance. Many papers that highlight the potential of neuroIS and that discuss methodological issues associated with using functional...... brain imaging already exist. However, neuroIS researchers have to keep in mind that the emergence of complex mental processes such as trust in IS contexts is based on activity in a network of brain regions rather than on activity in one area alone. Accordingly, we introduce psycho......-physiological interaction (PPI) analysis, a technique that one can use to analyze fMRI data. Specifically, we review how one can conduct PPI analysis, provide a concrete research example, and show how this analysis can inform IS trust research. Thus, we introduce neuroIS researchers working in the domain of functional...

  20. fMRI responses to Jung's Word Association Test: implications for theory, treatment and research.

    Science.gov (United States)

    Petchkovsky, Leon; Petchkovsky, Michael; Morris, Philip; Dickson, Paul; Montgomery, Danielle; Dwyer, Jonathan; Burnett, Patrick

    2013-06-01

    Jung's Word Association Test was performed under fMRI conditions by 12 normal subjects. Pooled complexed responses were contrasted against pooled neutral ones. The fMRI activation pattern of this generic 'complexed response' was very strong (corrected Z scores ranging from 4.90 to 5.69). The activation pattern in each hemisphere includes mirror neurone areas that track 'otherness' (perspectival empathy), anterior insula (both self-awareness and emotional empathy), and cingulated gyrus (self-awareness and conflict-monitoring). These are the sites described by Siegel and colleagues as the 'resonance circuitry' in the brain which is central to mindfulness (awareness of self) and empathy (sense of the other), negotiations between self awareness and the 'internal other'. But there is also an interhemispheric dialogue. Within 3 seconds, the left hemisphere over-rides the right (at least in our normal subjects). Mindfulness and empathy are central to good psychotherapy, and complexes can be windows of opportunity if left-brain hegemony is resisted. This study sets foundations for further research: (i) QEEG studies (with their finer temporal resolution) of complexed responses in normal subjects (ii) QEEG and fMRI studies of complexed responses in other conditions, like schizophrenia, PTSD, disorders of self organization. © 2013, The Society of Analytical Psychology.

  1. Open-Access, Low-Magnetic-Field MRI System for Lung Research

    Science.gov (United States)

    Mair, Ross W.; Rosen, Matthew S.; Tsai, Leo L.; Walsworth, Ronald L.; Hrovat, Mirko I.; Patz, Samuel; Ruset, Iullian C.; Hersman, F. William

    2009-01-01

    An open-access magnetic resonance imaging (MRI) system is being developed for use in research on orientational/gravitational effects on lung physiology and function. The open-access geometry enables study of human subjects in diverse orientations. This system operates at a magnetic flux density, considerably smaller than the flux densities of typical other MRI systems, that can be generated by resistive electromagnet coils (instead of the more-expensive superconducting coils of the other systems). The human subject inhales air containing He-3 or Xe-129 atoms, the nuclear spins of which have been polarized by use of a laser beam to obtain a magnetic resonance that enables high-resolution gas space imaging at the low applied magnetic field. The system includes a bi-planar, constant-current, four-coil electromagnet assembly and associated electronic circuitry to apply a static magnetic field of 6.5 mT throughout the lung volume; planar coils and associated circuitry to apply a pulsed magnetic-field-gradient for each spatial dimension; a single, detachable radio-frequency coil and associated circuitry for inducing and detecting MRI signals; a table for supporting a horizontal subject; and electromagnetic shielding surrounding the electromagnet coils.

  2. The OMERACT MRI inflammatory arthritis group: advances and future research priorities

    DEFF Research Database (Denmark)

    Conaghan, Philip G; Bird, Paul; McQueen, Fiona

    2009-01-01

    The OMERACT magnetic resonance imaging (MRI) in inflammatory arthritis group previously developed the rheumatoid arthritis MRI score (RAMRIS) for use in clinical studies, evaluated the use of extremity MRI, and initiated development of a psoriatic arthritis MRI score (PsAMRIS). At OMERACT 9 the g...

  3. NIRS report of utilization of MRI machine for research. Results in 2005

    International Nuclear Information System (INIS)

    2007-04-01

    The report is an achievement of cooperative research and development by private and official facilities of the National Institute of Radiological Sciences (NIRS) MRI machine, and its applied and medical uses in 2005. Contained are the reports on the magnet (1 topic), RF coils (5), basic studies on measurements (11), biological studies on measurements (4) and clinical studies on measurements (18), which are finally summarized in the list of the personnel, event calendar and published scientific papers. The basic studies by the MRI involve those of digestive tract's movement, samples for radiation dose measurements using polymer gel materials, disposition tracing of 5-FU by 19F chemical shift images, 19F images at 3T, 3T MRS, 13C measurement at 7T MR, spectrum at 7T MR, development of measurement system for elastic modulus distribution in living tissues, measurement of biological function by 170 MRI and measurement of acetylcholinesterase in brain. Biological studies involve those of the brain damage by heavy particle irradiation, functional brain mapping of monkey's abstract operation using PET, multiple sclerosis mice and development of a new cardiac function evaluation method. Clinical studies involve those of blood vessel coupling of cerebral nerve, micro-imaging of human eye, autopsy imaging, numerical phantom of human body, measurements of physiological parameters of brain, measurement of sugar metabolism function, radiation therapy evaluation method of brain tumors, metabolism analysis by 7T MR spectroscopy, statistical test of AChE activity, measurement of beta-amyloid in brain by Pittsburgh Compound-B, brain function, development of longitudinal relaxation time calculation software (T1Wizard), GSH in schizophrenia, evaluation method of forms and functions of hearts, occlusive arterial disease of lower extremity, MRI image of prostate using 3.0T, cholangiography, elucidation of activation mechanism of higher brain network by occlusal chew stimulation and MR

  4. Integration of ultra-high field MRI and histology for connectome based research of brain disorders

    Directory of Open Access Journals (Sweden)

    Shan eYang

    2013-09-01

    Full Text Available Ultra-high field magnetic resonance imaging (MRI became increasingly relevant for in vivo neuroscientific research because of improved spatial resolutions. However, this is still the unchallenged domain of histological studies, which long played an important role in the investigation of neuropsychiatric disorders. While the field of biological psychiatry strongly advanced on macroscopic levels, current developments are rediscovering the richness of immunohistological information when attempting a multi-level systematic approach to brain function and dysfunction. For most studies, histology sections lost information on three-dimensional reconstructions. Translating histological sections to 3D-volumes would thus not only allow for multi-stain and multi-subject alignment in post mortem data, but also provide a crucial step in big data initiatives involving the network analyses currently performed with in vivo MRI. We therefore investigated potential pitfalls during integration of MR and histological information where no additional blockface information is available. We demonstrated that strengths and requirements from both methods seem to be ideally merged at a spatial resolution of 200 μm. However, the success of this approach is heavily dependent on choices of hardware, sequence and reconstruction. We provide a fully automated pipeline that optimizes histological 3D reconstructions, providing a potentially powerful solution not only for primary human post mortem research institutions in neuropsychiatric research, but also to help alleviate the massive workloads in neuroanatomical atlas initiatives. We further demonstrate (for the first time the feasibility and quality of ultra-high spatial resolution (150 µm isotopic imaging of the entire human brain MRI at 7T, offering new opportunities for analyses on MR-derived information.

  5. Full automatic fiducial marker detection on coil arrays for accurate instrumentation placement during MRI guided breast interventions

    Science.gov (United States)

    Filippatos, Konstantinos; Boehler, Tobias; Geisler, Benjamin; Zachmann, Harald; Twellmann, Thorsten

    2010-02-01

    With its high sensitivity, dynamic contrast-enhanced MR imaging (DCE-MRI) of the breast is today one of the first-line tools for early detection and diagnosis of breast cancer, particularly in the dense breast of young women. However, many relevant findings are very small or occult on targeted ultrasound images or mammography, so that MRI guided biopsy is the only option for a precise histological work-up [1]. State-of-the-art software tools for computer-aided diagnosis of breast cancer in DCE-MRI data offer also means for image-based planning of biopsy interventions. One step in the MRI guided biopsy workflow is the alignment of the patient position with the preoperative MR images. In these images, the location and orientation of the coil localization unit can be inferred from a number of fiducial markers, which for this purpose have to be manually or semi-automatically detected by the user. In this study, we propose a method for precise, full-automatic localization of fiducial markers, on which basis a virtual localization unit can be subsequently placed in the image volume for the purpose of determining the parameters for needle navigation. The method is based on adaptive thresholding for separating breast tissue from background followed by rigid registration of marker templates. In an evaluation of 25 clinical cases comprising 4 different commercial coil array models and 3 different MR imaging protocols, the method yielded a sensitivity of 0.96 at a false positive rate of 0.44 markers per case. The mean distance deviation between detected fiducial centers and ground truth information that was appointed from a radiologist was 0.94mm.

  6. PET/MRI. Challenges, solutions and perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Herzog, Hans [Forschungszentrum Juelich (Germany). Inst. of Neuroscience and Medicine - 4

    2012-07-01

    Already from the start of PET/CT integrating positron emission tomography (PET) and computed tomography (CT) in one instrument, there have been considerations how to combine PET and magnetic resonance imaging (MRI) so that their complementary abilities can be utilized in a single investigation. Since classical PET electronics fail in an even weak magnetic field and PET signal processing might disturb high-frequency signals of MRI, it soon became clear that new solutions had to be found to avoid mutual interferences. During the last fifteen years a number of different approaches towards PET/MRI for small animal imaging have been developed by research groups which together with their specific features are summarized in this review. Recently, PET/MRI for human imaging became available as well - this time by industrial initiatives. First some prototypes of BrainPET/MRI were developed followed by commercial products for simultaneous and non-simultaneous whole-body PET/MRI. Although only PET/MRI integrated in one scanner offers the full diversity of complementary multiparametric imaging, there are also promising applications of non-simultaneous sequential PET/MRI. While describing the present instrumentation for human PET/MRI, this review discusses the challenges and promises related to this new imaging technology. (orig.)

  7. Cross-cultural adaptation of research instruments: language, setting, time and statistical considerations.

    Science.gov (United States)

    Gjersing, Linn; Caplehorn, John R M; Clausen, Thomas

    2010-02-10

    Research questionnaires are not always translated appropriately before they are used in new temporal, cultural or linguistic settings. The results based on such instruments may therefore not accurately reflect what they are supposed to measure. This paper aims to illustrate the process and required steps involved in the cross-cultural adaptation of a research instrument using the adaptation process of an attitudinal instrument as an example. A questionnaire was needed for the implementation of a study in Norway 2007. There was no appropriate instruments available in Norwegian, thus an Australian-English instrument was cross-culturally adapted. The adaptation process included investigation of conceptual and item equivalence. Two forward and two back-translations were synthesized and compared by an expert committee. Thereafter the instrument was pretested and adjusted accordingly. The final questionnaire was administered to opioid maintenance treatment staff (n=140) and harm reduction staff (n=180). The overall response rate was 84%. The original instrument failed confirmatory analysis. Instead a new two-factor scale was identified and found valid in the new setting. The failure of the original scale highlights the importance of adapting instruments to current research settings. It also emphasizes the importance of ensuring that concepts within an instrument are equal between the original and target language, time and context. If the described stages in the cross-cultural adaptation process had been omitted, the findings would have been misleading, even if presented with apparent precision. Thus, it is important to consider possible barriers when making a direct comparison between different nations, cultures and times.

  8. Field astrobiology research instruments and methods in moon-mars analogue site.

    NARCIS (Netherlands)

    Foing, B.H.; Stoker, C.; Zavaleta, J.; Ehrenfreund, P.; Sarrazin, P.; Blake, D.; Page, J.; Pletser, V.; Hendrikse, J.; Oliveira Lebre Direito, M.S.; Kotler, M.; Martins, Z.; Orzechowska, G.; Thiel, C.S.; Clarke, J.; Gross, J.; Wendt, L.; Borst, A.; Peters, S.; Wilhelm, M.-B.; Davies, G.R.; EuroGeoMars 2009 Team, ILEWG

    2011-01-01

    We describe the field demonstration of astrobiology instruments and research methods conducted in and from the Mars Desert Research Station (MDRS) in Utah during the EuroGeoMars campaign 2009 coordinated by ILEWG, ESA/ESTEC and NASA Ames, with the contribution of academic partners. We discuss the

  9. Toward cardiovascular MRI at 7 T: clinical needs, technical solutions and research promises

    International Nuclear Information System (INIS)

    Niendorf, Thoralf; Sodickson, Daniel K.; Krombach, Gabriele A.; Schulz-Menger, Jeanette

    2010-01-01

    To consider potential clinical needs, technical solutions and research promises of ultrahigh-field strength cardiovascular MR (CMR). A literature review is given, surveying advantages and disadvantages of CMR at ultrahigh fields (UHF). Key concepts, emerging technologies, practical considerations and applications of UHF CMR are provided. Examples of UHF CMR imaging strategies and their added value are demonstrated, including the numerous unsolved problems. A concluding section explores future directions in UHF CMR. UHF CMR can be regarded as one of the most challenging MRI applications. Image quality achievable at UHF is not always exclusively defined by signal-to-noise considerations. Some of the inherent advantages of UHF MRI are offset by practical challenges. But UHF CMR can boast advantages over its kindred lower field counterparts by trading the traits of high magnetic fields for increased temporal and/or spatial resolution. CMR at ultrahigh-field strengths is a powerful motivator, since speed and signal may be invested to overcome the fundamental constraints that continue to hamper traditional CMR. If practical challenges can be overcome, UHF CMR will help to open the door to new approaches for basic science and clinical research. (orig.)

  10. A basic design of SR4 instrumentation and control system for research reactor

    International Nuclear Information System (INIS)

    Syahrudin Yusuf; M Subhan; Ikhsan Shobari; Sutomo Budihardjo

    2010-01-01

    An SR4 instrumentation and control systems of research reactor is the equipment of nuclear research reactors as power protection devices and control systems. The equipment is to monitor safety parameters and process parameters in the state of reactor shut down, start-up, and in operation at fixed power. In the engineering of Instrumentation and control systems SR4 research reactor, its basic design consists of technical specifications of the reactor protection system devices, technical specifications of the reactor power control system devices, technical specifications information system devices, and systems process termination cabling as a support system. This basic design is used as the basis for the preparation of detailed design and subsequent engineering development of instrumentation systems and control system integrated. (author)

  11. MRI Primer

    International Nuclear Information System (INIS)

    Oldendorf, W.; Oldendorf, W. Jr.

    1991-01-01

    Designed for studies, radiologists, and clinicians at all levels of training, this book provides a basic introduction to the principles, physics, and instrumentation of magnetic resonance imaging. The fundamental concepts that are essential for the optimal clinical use of MRI are thoroughly explained in easily accessible terms. To facilitate the reader's comprehension, the material is presented nonmathematically, using no equations and a minimum of symbols and abbreviations. MRI Primer presents a clear account of the phenomenon of nuclear magnetic resonance and the use of gradient magnetic fields to create clinically useful images of cross-sectional slices. Close attention is given to the magnetization vector as a means of expressing nuclear behavior, the role of T 1 and T 2 weighing in imaging, the use of contrast agents, and the pulse sequences most often used in clinical practice, as well as to the relative capabilities and limitations of MRI and CT. The basic hardware components of an MRI scanner are described in detail. Sample MRI scans illustrate how MRI characterizes tissue. An appendix provides a brief introduction to quantum processes in MRI

  12. The Society for Implementation Research Collaboration Instrument Review Project: a methodology to promote rigorous evaluation.

    Science.gov (United States)

    Lewis, Cara C; Stanick, Cameo F; Martinez, Ruben G; Weiner, Bryan J; Kim, Mimi; Barwick, Melanie; Comtois, Katherine A

    2015-01-08

    Identification of psychometrically strong instruments for the field of implementation science is a high priority underscored in a recent National Institutes of Health working meeting (October 2013). Existing instrument reviews are limited in scope, methods, and findings. The Society for Implementation Research Collaboration Instrument Review Project's objectives address these limitations by identifying and applying a unique methodology to conduct a systematic and comprehensive review of quantitative instruments assessing constructs delineated in two of the field's most widely used frameworks, adopt a systematic search process (using standard search strings), and engage an international team of experts to assess the full range of psychometric criteria (reliability, construct and criterion validity). Although this work focuses on implementation of psychosocial interventions in mental health and health-care settings, the methodology and results will likely be useful across a broad spectrum of settings. This effort has culminated in a centralized online open-access repository of instruments depicting graphical head-to-head comparisons of their psychometric properties. This article describes the methodology and preliminary outcomes. The seven stages of the review, synthesis, and evaluation methodology include (1) setting the scope for the review, (2) identifying frameworks to organize and complete the review, (3) generating a search protocol for the literature review of constructs, (4) literature review of specific instruments, (5) development of an evidence-based assessment rating criteria, (6) data extraction and rating instrument quality by a task force of implementation experts to inform knowledge synthesis, and (7) the creation of a website repository. To date, this multi-faceted and collaborative search and synthesis methodology has identified over 420 instruments related to 34 constructs (total 48 including subconstructs) that are relevant to implementation

  13. Considerations in the construction of an instrument to assess attitudes regarding critical illness gene variation research.

    Science.gov (United States)

    Freeman, Bradley D; Kennedy, Carie R; Bolcic-Jankovic, Dragana; Eastman, Alexander; Iverson, Ellen; Shehane, Erica; Celious, Aaron; Barillas, Jennifer; Clarridge, Brian

    2012-02-01

    Clinical studies conducted in intensive care units are associated with logistical and ethical challenges. Diseases investigated are precipitous and life-threatening, care is highly technological, and patients are often incapacitated and decision-making is provided by surrogates. These investigations increasingly involve collection of genetic data. The manner in which the exigencies of critical illness impact attitudes regarding genetic data collection is unstudied. Given interest in understanding stakeholder preferences as a foundation for the ethical conduct of research, filling this knowledge gap is timely. The conduct of opinion research in the critical care arena is novel. This brief report describes the development of parallel patient/surrogate decision-maker quantitative survey instruments for use in this environment. Future research employing this instrument or a variant of it with diverse populations promises to inform research practices in critical illness gene variation research.

  14. CONCEPTUAL AND DESIGN ISSUES IN INSTRUMENT DEVELOPMENT FOR RESEARCH WITH BEREAVED PARENTS*

    Science.gov (United States)

    Briller, Sherylyn H.; Schim, Stephanie Myers; Thurston, Celia S.; Meert, Kathleen L.

    2013-01-01

    Many childhood deaths in the United States occur in pediatric intensive care units (PICUs) and parents have special needs in this death context. As an interdisciplinary research team, we discuss conceptual and design issues encountered in creating a new instrument, the Bereaved Parent Needs Assessment–PICU, for assessing parents’ needs in this setting. Using a qualitative approach, our team previously explored how the culture and related ways of providing care in one urban Midwestern children’s hospital PICU affected parents’ bereavement needs and experiences. We describe using this qualitative foundation in the development of a new quantitative instrument to more widely validate and measure bereaved parents’ needs around the time of a child’s death across multiple PICUs. We highlight a series of issues that warrant consideration in designing a research instrument for this vulnerable population including setting and context, format and content, temporality, recruitment, and content expertise. PMID:22953511

  15. Environmental policy instruments and technological change in the energy sector: findings from comparative empirical research

    International Nuclear Information System (INIS)

    Skjaerseth, J.B.; Christiansen, A.C.

    2006-01-01

    This article explores the extent to which and in what ways environmental policy instruments may affect patterns of environmental friendly technological change in the energy sector. Our argument is based on the assumption, however, that technological change is also affected by the political context in which the instruments are applied and by the nature of the problem itself. Comparative empirical research involving different European countries, sectors and policy fields were examined, including climate change, air pollution and wind power. The relationship between environmental policy instruments and technological change is extremely complex, not least due to the impact of other factors that may be more decisive than environmental ones. Against this backdrop, it was concluded that: 1) a portfolio of policy instruments works to the extent that different types of policy instruments affect the different drivers and stages behind technological change needed to solve specific problems. The need for a portfolio of policy instruments depends on the technological challenge being faced; 2) voluntary approaches facilitated constructive corporate strategies, but mandatory approaches tended to be more effective in stimulating short term major technological change; 3) voluntary approaches work well in the short term when the problem to be solved is characterized by lack of information and coordination. (author)

  16. 3D printing of MRI compatible components: why every MRI research group should have a low-budget 3D printer.

    Science.gov (United States)

    Herrmann, Karl-Heinz; Gärtner, Clemens; Güllmar, Daniel; Krämer, Martin; Reichenbach, Jürgen R

    2014-10-01

    To evaluate low budget 3D printing technology to create MRI compatible components. A 3D printer is used to create customized MRI compatible components, a loop-coil platform and a multipart mouse fixation. The mouse fixation is custom fit for a dedicated coil and facilitates head fixation with bite bar, anesthetic gas supply and biomonitoring sensors. The mouse fixation was tested in a clinical 3T scanner. All parts were successfully printed and proved MR compatible. Both design and printing were accomplished within a few days and the final print results were functional with well defined details and accurate dimensions (Δ3D printer can be used to quickly progress from a concept to a functional device at very low production cost. While 3D printing technology does impose some restrictions on model geometry, additive printing technology can create objects with complex internal structures that can otherwise not be created by using lathe technology. Thus, we consider a 3D printer a valuable asset for MRI research groups. Copyright © 2014 IPEM. Published by Elsevier Ltd. All rights reserved.

  17. Research pressure instrumentation for NASA Space Shuttle main engine, modification no. 5

    Science.gov (United States)

    Anderson, P. J.; Nussbaum, P.; Gustafson, G.

    1984-01-01

    Research concerning the development of pressure instrumentation for the space shuttle main engine is reported. The following specific topics were addressed: (1) transducer design and materials, (2) silicon piezoresistor characterization at cryogenic temperatures, (3) chip mounting characterization, and (4) frequency response optimization.

  18. An ergonomics based design research method for the arrangement of helicopter flight instrument panels.

    Science.gov (United States)

    Alppay, Cem; Bayazit, Nigan

    2015-11-01

    In this paper, we study the arrangement of displays in flight instrument panels of multi-purpose civil helicopters following a user-centered design method based on ergonomics principles. Our methodology can also be described as a user-interface arrangement methodology based on user opinions and preferences. This study can be outlined as gathering user-centered data using two different research methods and then analyzing and integrating the collected data to come up with an optimal instrument panel design. An interview with helicopter pilots formed the first step of our research. In that interview, pilots were asked to provide a quantitative evaluation of basic interface arrangement principles. In the second phase of the research, a paper prototyping study was conducted with same pilots. The final phase of the study entailed synthesizing the findings from interviews and observational studies to formulate an optimal flight instrument arrangement methodology. The primary results that we present in our paper are the methodology that we developed and three new interface arrangement concepts, namely relationship of inseparability, integrated value and locational value. An optimum instrument panel arrangement is also proposed by the researchers. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  19. Development of instrumentation in the transport phenomena research in thermal equipment

    International Nuclear Information System (INIS)

    Carvalho Tofani, P. de; Ladeira, L.C.D.

    1983-11-01

    The results obtained from the effort on the acquisition of know-how in experimental reactor thermal during the last years, through the approach of relevant aspects of basic research on transport phenomena applicable to nuclear reactor analysis and conventional thermal equipment based in the simultaneous development of instrumentation and experimental methods are presented. (E.G.) [pt

  20. Radiation protection commissioning of neutron beam instruments at the OPAL research reactor

    International Nuclear Information System (INIS)

    Parkes, Alison; Saratsopoulos, John; Deura, Michael; Kenny, Pat

    2008-01-01

    The neutron beam facilities at the 20 MW OPAL Research Reactor were commissioned in 2007 and 2008. The initial suite of eight neutron beam instruments on two thermal neutron guides, two cold neutron guides and one thermal beam port located at the reactor face, together with their associated shielding were progressively installed and commissioned according to their individual project plans. Radiation surveys were systematically conducted as reactor power was raised in a step-wise manner to 20 MW in order to validate instrument shielding design and performance. The performance of each neutron guide was assessed by neutron energy spectrum and flux measurements. The activation of beam line components, decay times assessments and access procedures for Bragg Institute beam instrument scientists were established. The multiple configurations for each instrument and the influence of operating more than one instrument or beamline simultaneously were also tested. Areas of interest were the shielding around the secondary shutters, guide shield and bunker shield interfaces and monochromator doors. The shielding performance, safety interlock checks, improvements, radiation exposures and related radiation protection challenges are discussed. This paper discusses the health physics experience of commissioning the OPAL Research Reactor neutron beam facilities and describes health physics results, actions taken and lessons learned during commissioning. (author)

  1. Research progress of MRI in preoperative evaluation of pituitary adenoma's consistency

    International Nuclear Information System (INIS)

    Lu Yiping; Yin Bo; Geng Daoying

    2013-01-01

    As the most common primary disease in pituitary fossa, the incidence of pituitary adenoma ranks 3rd in the primary tumors of the brain. To remove those resectable pituitary adenomas, there are 2 surgical approaches, named trans-sphenoidal endoscopic surgery and craniotomy. Which approach should be used depends on the size, invasive extension and the consistency of the tumors. The trans-sphenoidal endoscopic surgery is more suitable for the tumors with soft consistency which are easy to pull out, while the craniotomy is suitable for the hard ones. So, preoperative evaluation of the tumors' consistency can help to find the best surgical approach and treatments. MRI is not only an ideal method to show the structure of brain, but also can be used to evaluate consistency of tumor. This review illustrated the forming mechanism of the different consistency of pituitary adenoma and the research process in evaluating the consistency. (authors)

  2. The instrumentation of the prestressed concrete vessel with hot liner at Seibersdorf Research Centre

    International Nuclear Information System (INIS)

    Zemann, H.

    1975-11-01

    The joint project ''Prestressed Concrete Pressure Vessel with Hot Liner'' at Seibersdorf Research Centre now is in the process of testing the PCPV both in construction and operation from the safety point of view. The physical state of the PCPV (modulus of elasticity, humidity of concrete, creeping, etc.) is brought to stable conditions by ''pre-aging''. In order to control this process of stabilisation, an extensive knowledge of the concrete and an elaborated instrumentation is a necessity. This paper presents a survey about the philosophy and the realisation of the instrumentation of the PCPV and the investigations we performed to interpret the measurements. (author)

  3. Research reactor instrumentation and control technology. Report of a technical committee meeting

    International Nuclear Information System (INIS)

    1997-10-01

    The majority of research reactors operating today were put into operation 20 years ago, and some of them underwent modifications, upgrading and refurbishing since their construction to meet the requirements for higher neutron fluxes. However, a few of these ageing research reactors are still operating with their original instrumentation and control systems (I and C) which are important for reactor safety to guard against abnormal occurrences and reactor control involving startup, shutdown and power regulation. Worn and obsolete I and C systems cause operational problems as well as difficulties in obtaining replacement parts. In addition, satisfying the stringent safety conditions laid out by the nuclear regulatory bodies requires the modernization of research reactors I and C systems and integration of additional instrumentation units to the reactor. In order to clarify these issues and to provide some guidance to reactor operators on state-of-art technology and future trends for the I and C systems for research reactors, a Technical Committee Meeting on Technology and Trends for Research Reactor Instrumentation and Controls was held in Ljubljana, Slovenia, from 4 to 8 December 1995. This publication summarizes the discussions and recommendations resulting from that meeting. This is expected to benefit the research reactor operators planning I and C improvements. Refs, figs, tabs

  4. Incorporation of personal computers in a research reactor instrumentation system for data monitoring and analysis

    International Nuclear Information System (INIS)

    Leopando, L.S.

    1998-01-01

    The research contract was implemented by obtaining off-the shelf personal computer hardware and data acquisition cards, designing the interconnection with the instrumentation system, writing and debugging the software, and the assembling and testing the set-up. The hardware was designed to allow all variables monitored by the instrumentation system to be accessible to the computers, without requiring any major modification of the instrumentation system and without compromising reactor safety in any way. The computer hardware addition was also designed to have no effect on any existing function of the instrumentation system. The software was designed to implement only graphical display and automated logging of reactor variables. Additional functionality could be easily added in the future with software revision because all the reactor variables are already available in the computer. It would even be possible to ''close the loop'' and control the reactor through software. It was found that most of the effort in an undertaking of this sort will be in software development, but the job can be done even by non-computer specialized reactor people working with programming languages they are already familiar with. It was also found that the continuing rapid advance of personal computer technology makes it essential that such a project be undertaken with inevitability of future hardware upgrading in mind. The hardware techniques and the software developed may find applicability in other research reactors, especially those with a generic analog research reactor TRIGA console. (author)

  5. PET/MRI for neurologic applications.

    Science.gov (United States)

    Catana, Ciprian; Drzezga, Alexander; Heiss, Wolf-Dieter; Rosen, Bruce R

    2012-12-01

    PET and MRI provide complementary information in the study of the human brain. Simultaneous PET/MRI data acquisition allows the spatial and temporal correlation of the measured signals, creating opportunities impossible to realize using stand-alone instruments. This paper reviews the methodologic improvements and potential neurologic and psychiatric applications of this novel technology. We first present methods for improving the performance and information content of each modality by using the information provided by the other technique. On the PET side, we discuss methods that use the simultaneously acquired MRI data to improve the PET data quantification. On the MRI side, we present how improved PET quantification can be used to validate several MRI techniques. Finally, we describe promising research, translational, and clinical applications that can benefit from these advanced tools.

  6. Evaluating Research-Oriented Teaching: A New Instrument to Assess University Students' Research Competences

    Science.gov (United States)

    Böttcher, Franziska; Thiel, Felicitas

    2018-01-01

    Several concepts have been developed to implement research-oriented teaching in higher education in the last 15 years. The definition of research competences, however, has received minor attention so far. Some approaches to modeling research competences describe these competences along the research process but either focus on a specific academic…

  7. A selective review of the first 20 years of instrumental variables models in health-services research and medicine.

    Science.gov (United States)

    Cawley, John

    2015-01-01

    The method of instrumental variables (IV) is useful for estimating causal effects. Intuitively, it exploits exogenous variation in the treatment, sometimes called natural experiments or instruments. This study reviews the literature in health-services research and medical research that applies the method of instrumental variables, documents trends in its use, and offers examples of various types of instruments. A literature search of the PubMed and EconLit research databases for English-language journal articles published after 1990 yielded a total of 522 original research articles. Citations counts for each article were derived from the Web of Science. A selective review was conducted, with articles prioritized based on number of citations, validity and power of the instrument, and type of instrument. The average annual number of papers in health services research and medical research that apply the method of instrumental variables rose from 1.2 in 1991-1995 to 41.8 in 2006-2010. Commonly-used instruments (natural experiments) in health and medicine are relative distance to a medical care provider offering the treatment and the medical care provider's historic tendency to administer the treatment. Less common but still noteworthy instruments include randomization of treatment for reasons other than research, randomized encouragement to undertake the treatment, day of week of admission as an instrument for waiting time for surgery, and genes as an instrument for whether the respondent has a heritable condition. The use of the method of IV has increased dramatically in the past 20 years, and a wide range of instruments have been used. Applications of the method of IV have in several cases upended conventional wisdom that was based on correlations and led to important insights about health and healthcare. Future research should pursue new applications of existing instruments and search for new instruments that are powerful and valid.

  8. Update on research and future directions of the OMERACT MRI inflammatory arthritis group

    DEFF Research Database (Denmark)

    Conaghan, Philip G; McQueen, Fiona M; Bird, Paul

    2011-01-01

    of this score will require more PsA imaging datasets. As well, due to improved image resolution since the development of the original rheumatoid arthritis MRI scoring system (RAMRIS), the Task Force has worked on semiquantitative assessment of joint space narrowing, and developed a reliable method......The OMERACT Magnetic Resonance Imaging (MRI) Task Force has developed and evolved the psoriatic arthritis MRI score (PsAMRIS) over the last few years, and at OMERACT 10, presented longitudinal evaluation by multiple readers, using PsA datasets obtained from extremity MRI magnets. Further evaluation...

  9. Heterogeneous Optimization Framework: Reproducible Preprocessing of Multi-Spectral Clinical MRI for Neuro-Oncology Imaging Research

    OpenAIRE

    Milchenko, Mikhail; Snyder, Abraham Z.; LaMontagne, Pamela; Shimony, Joshua S; Benzinger, Tammie L.; Fouke, Sarah Jost; Marcus, Daniel S.

    2016-01-01

    Neuroimaging research often relies on clinically acquired magnetic resonance imaging (MRI) datasets that can originate from multiple institutions. Such datasets are characterized by high heterogeneity of modalities and variability of sequence parameters. This heterogeneity complicates the automation of image processing tasks such as spatial co-registration and physiological or functional image analysis.

  10. INSTRUMENTS OF SUPPORT FOR RESEARCH AND DEVELOPMENT FUNDED BY LEADING DOMESTIC AND INTERNATIONAL SCIENCE FOUNDATIONS

    Directory of Open Access Journals (Sweden)

    Irina E. Ilina

    2017-06-01

    Full Text Available Introduction: one of the key aspects of the knowledge economy development is the growing significance of the results of research and development. The education and basic research play a key role in this process. Funding for education and fundamental science is carried out mainly at the expense of the state resources, including a system of foundations for scientific, engineering and innovation activities in Russia. The purpose of this article is to present recommendations for improving the tools of domestic foundations in funding fundamental research and development, including education and training. The propositions are made with a comparative analysis of the domestic and foreign science foun dations’ activities. Materials and Methods: the authors used analysis, comparison, induction, deduction, graphical analysis, generalisation and other scientific methods during the study. Results: the lack of comparability between domestic and foreign scientific funds in the volume of funding allocated for basic research and development is revealed. This situation affects the scientific research. The foreign foundations have a wide range of instruments to support research projects at all stages of the life cycle of grants for education and training prior to release of an innovative product to market (the use of “innovation elevator” system. The Russian national scientific foundations have no such possibilities. The authors guess that the Russian organisations ignore some of the instruments for supporting research and development. Use of these tools could enhance the effectiveness of research projects. According to the study of domestic and foreign experience in supporting research and development, the authors proposed a matrix composed of instruments for support in the fields of basic scientific researches and education with such phases of the project life cycle as “research” and “development”. Discussion and Conclusions: the foreign science

  11. Heart MRI

    Science.gov (United States)

    Magnetic resonance imaging - cardiac; Magnetic resonance imaging - heart; Nuclear magnetic resonance - cardiac; NMR - cardiac; MRI of the heart; Cardiomyopathy - MRI; Heart failure - MRI; Congenital heart disease - MRI

  12. U.S. Department of Energy instrumentation and controls technology research for advanced small modular reactors

    International Nuclear Information System (INIS)

    Wood, Richard Thomas

    2013-01-01

    Instrumentation, controls, and human-machine interfaces (ICHMI) are essential enabling technologies that strongly influence nuclear power plant performance and operational costs. The U.S. Department of Energy (DOE) has recognized that ICHMI research, development, and demonstration (RD and D) is needed to resolve the technical challenges that may compromise the effective and efficient utilization of modern ICHMI technology and consequently inhibit realization of the benefits offered by expanded utilization of nuclear power. Consequently, key DOE programs have substantial ICHMI RD and D elements to their respective research portfolio. This article describes current ICHMI research to support the development of advanced small modular reactors. (author)

  13. Understanding practice change in community pharmacy: a qualitative research instrument based on organisational theory.

    Science.gov (United States)

    Roberts, Alison S; Hopp, Trine; Sørensen, Ellen Westh; Benrimoj, Shalom I; Chen, Timothy F; Herborg, Hanne; Williams, Kylie; Aslani, Parisa

    2003-10-01

    The past decade has seen a notable shift in the practice of pharmacy, with a strong focus on the provision of cognitive pharmaceutical services (CPS) by community pharmacists. The benefits of these services have been well documented, yet their uptake appears to be slow. Various strategies have been developed to overcome barriers to the implementation of CPS, with varying degrees of success, and little is known about the sustainability of the practice changes they produce. Furthermore, the strategies developed are often specific to individual programs or services, and their applicability to other CPS has not been explored. There seems to be a need for a flexible change management model for the implementation and dissemination of a range of CPS, but before it can be developed, a better understanding of the change process is required. This paper describes the development of a qualitative research instrument that may be utilised to investigate practice change in community pharmacy. Specific objectives included gaining knowledge about the circumstances surrounding attempts to implement CPS, and understanding relationships that are important to the change process. Organisational theory provided the conceptual framework for development of the qualitative research instrument, within which two theories were used to give insight into the change process: Borum's theory of organisational change, which categorizes change strategies as rational, natural, political or open; and Social Network Theory, which helps identify and explain the relationships between key people involved in the change process. A semi-structured affecting practice change found in the literature that warranted further investigation with the theoretical perspectives of organisational change and social networks. To address the research objectives, the instrument covered four broad themes: roles, experiences, strategies and networks. The qualitative research instrument developed in this study provides a

  14. Occupational exposure of healthcare and research staff to static magnetic stray fields from 1.5–7 Tesla MRI scanners is associated with reporting of transient symptoms

    Science.gov (United States)

    Schaap, Kristel; Christopher-de Vries, Yvette; Mason, Catherine K; de Vocht, Frank; Portengen, Lützen; Kromhout, Hans

    2014-01-01

    Objectives Limited data is available about incidence of acute transient symptoms associated with occupational exposure to static magnetic stray fields from MRI scanners. We aimed to assess the incidence of these symptoms among healthcare and research staff working with MRI scanners, and their association with static magnetic field exposure. Methods We performed an observational study among 361 employees of 14 clinical and research MRI facilities in The Netherlands. Each participant completed a diary during one or more work shifts inside and/or outside the MRI facility, reporting work activities and symptoms (from a list of potentially MRI-related symptoms, complemented with unrelated symptoms) experienced during a working day. We analysed 633 diaries. Exposure categories were defined by strength and type of MRI scanner, using non-MRI shifts as the reference category for statistical analysis. Non-MRI shifts originated from MRI staff who also participated on MRI days, as well as CT radiographers who never worked with MRI. Results Varying per exposure category, symptoms were reported during 16–39% of the MRI work shifts. We observed a positive association between scanner strength and reported symptoms among healthcare and research staff working with closed-bore MRI scanners of 1.5 Tesla (T) and higher (1.5 T OR=1.88; 3.0 T OR=2.14; 7.0 T OR=4.17). This finding was mainly driven by reporting of vertigo and metallic taste. Conclusions The results suggest an exposure-response association between exposure to strong static magnetic fields (and associated motion-induced time-varying magnetic fields) and reporting of transient symptoms on the same day of exposure. Trial registration number 11-032/C PMID:24714654

  15. The potential of infant fMRI research and the study of early life stress as a promising exemplar

    Directory of Open Access Journals (Sweden)

    Alice M. Graham

    2015-04-01

    Full Text Available Functional magnetic resonance imaging (fMRI research with infants and toddlers has increased rapidly over the past decade, and provided a unique window into early brain development. In the current report, we review the state of the literature, which has established the feasibility and utility of task-based fMRI and resting state functional connectivity MRI (rs-fcMRI during early periods of brain maturation. These methodologies have been successfully applied beginning in the neonatal period to increase understanding of how the brain both responds to environmental stimuli, and becomes organized into large-scale functional systems that support complex behaviors. We discuss the methodological challenges posed by this promising area of research. We also highlight that despite these challenges, early work indicates a strong potential for these methods to influence multiple research domains. As an example, we focus on the study of early life stress and its influence on brain development and mental health outcomes. We illustrate the promise of these methodologies for building on, and making important contributions to, the existing literature in this field.

  16. Toward biotechnology in space: High-throughput instruments for in situ biological research beyond Earth.

    Science.gov (United States)

    Karouia, Fathi; Peyvan, Kianoosh; Pohorille, Andrew

    2017-11-15

    Space biotechnology is a nascent field aimed at applying tools of modern biology to advance our goals in space exploration. These advances rely on our ability to exploit in situ high throughput techniques for amplification and sequencing DNA, and measuring levels of RNA transcripts, proteins and metabolites in a cell. These techniques, collectively known as "omics" techniques have already revolutionized terrestrial biology. A number of on-going efforts are aimed at developing instruments to carry out "omics" research in space, in particular on board the International Space Station and small satellites. For space applications these instruments require substantial and creative reengineering that includes automation, miniaturization and ensuring that the device is resistant to conditions in space and works independently of the direction of the gravity vector. Different paths taken to meet these requirements for different "omics" instruments are the subjects of this review. The advantages and disadvantages of these instruments and technological solutions and their level of readiness for deployment in space are discussed. Considering that effects of space environments on terrestrial organisms appear to be global, it is argued that high throughput instruments are essential to advance (1) biomedical and physiological studies to control and reduce space-related stressors on living systems, (2) application of biology to life support and in situ resource utilization, (3) planetary protection, and (4) basic research about the limits on life in space. It is also argued that carrying out measurements in situ provides considerable advantages over the traditional space biology paradigm that relies on post-flight data analysis. Published by Elsevier Inc.

  17. Measurements in quantitative research: how to select and report on research instruments.

    Science.gov (United States)

    Hagan, Teresa L

    2014-07-01

    Measures exist to numerically represent degrees of attributes. Quantitative research is based on measurement and is conducted in a systematic, controlled manner. These measures enable researchers to perform statistical tests, analyze differences between groups, and determine the effectiveness of treatments. If something is not measurable, it cannot be tested.

  18. The Use of Cronbach's Alpha When Developing and Reporting Research Instruments in Science Education

    Science.gov (United States)

    Taber, Keith S.

    2017-06-01

    Cronbach's alpha is a statistic commonly quoted by authors to demonstrate that tests and scales that have been constructed or adopted for research projects are fit for purpose. Cronbach's alpha is regularly adopted in studies in science education: it was referred to in 69 different papers published in 4 leading science education journals in a single year (2015)—usually as a measure of reliability. This article explores how this statistic is used in reporting science education research and what it represents. Authors often cite alpha values with little commentary to explain why they feel this statistic is relevant and seldom interpret the result for readers beyond citing an arbitrary threshold for an acceptable value. Those authors who do offer readers qualitative descriptors interpreting alpha values adopt a diverse and seemingly arbitrary terminology. More seriously, illustrative examples from the science education literature demonstrate that alpha may be acceptable even when there are recognised problems with the scales concerned. Alpha is also sometimes inappropriately used to claim an instrument is unidimensional. It is argued that a high value of alpha offers limited evidence of the reliability of a research instrument, and that indeed a very high value may actually be undesirable when developing a test of scientific knowledge or understanding. Guidance is offered to authors reporting, and readers evaluating, studies that present Cronbach's alpha statistic as evidence of instrument quality.

  19. Analysis and upgrade of instrumentation and control systems for the modernization of research reactors

    International Nuclear Information System (INIS)

    1988-01-01

    This document provides assistance in the review and planning process for the upgrade of instrumentation and control systems (I and C systems) and related safety features of the reactor protection system for research reactors. In the interest of safety a need was realized to evaluate the performance of outdated I and C systems. An advisory group was assembled to develop guidelines and to provide recommendations for the upgrade of I and C systems. The recommendations on I and C systems upgrade contained in this document were developed by the advisory group using as guidelines the established safety criteria and operating standards for research reactors. 24 refs

  20. Variability of carotid artery measurements on 3-Tesla MRI and its impact on sample size calculation for clinical research.

    Science.gov (United States)

    Syed, Mushabbar A; Oshinski, John N; Kitchen, Charles; Ali, Arshad; Charnigo, Richard J; Quyyumi, Arshed A

    2009-08-01

    Carotid MRI measurements are increasingly being employed in research studies for atherosclerosis imaging. The majority of carotid imaging studies use 1.5 T MRI. Our objective was to investigate intra-observer and inter-observer variability in carotid measurements using high resolution 3 T MRI. We performed 3 T carotid MRI on 10 patients (age 56 +/- 8 years, 7 male) with atherosclerosis risk factors and ultrasound intima-media thickness > or =0.6 mm. A total of 20 transverse images of both right and left carotid arteries were acquired using T2 weighted black-blood sequence. The lumen and outer wall of the common carotid and internal carotid arteries were manually traced; vessel wall area, vessel wall volume, and average wall thickness measurements were then assessed for intra-observer and inter-observer variability. Pearson and intraclass correlations were used in these assessments, along with Bland-Altman plots. For inter-observer variability, Pearson correlations ranged from 0.936 to 0.996 and intraclass correlations from 0.927 to 0.991. For intra-observer variability, Pearson correlations ranged from 0.934 to 0.954 and intraclass correlations from 0.831 to 0.948. Calculations showed that inter-observer variability and other sources of error would inflate sample size requirements for a clinical trial by no more than 7.9%, indicating that 3 T MRI is nearly optimal in this respect. In patients with subclinical atherosclerosis, 3 T carotid MRI measurements are highly reproducible and have important implications for clinical trial design.

  1. Operational parameters study of IPR-R1 TRIGA research reactor using virtual instruments

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, Antonio Juscelino; Mesquita, Amir Zacarias; Lameiras, Fernando Soares, E-mail: ajp@cdtn.br, E-mail: amir@cdtn.br, E-mail: fsl@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2013-07-01

    The instrumentation of nuclear reactors is designed with the principle of reliability, redundancy and diversification of control systems. Reliable monitoring of the parameters involved in the chain reaction is of great importance regarding efficiency and operational safety of the installation. The main goal of the simulation system in this proposed paper is to provide the study and improvement in understanding how these operational variables are interrelated and their behavior especially those related to neutronic and thermohydraulics. The work will be developed using the software LabVIEW ® (Laboratory Virtual Instruments Engineering Workbench). The program will enable the study of the variables involved in the operation of the installation throughout its operating range, for instance, a few mW up to 250 kW. The IPR-R1 TRIGA is a research nuclear reactor placed in open pool and cooled by light water with natural circulation. It is located at the Nuclear Technology Development Center (CDTN), in Belo Horizonte Brazil. The developing system employs the modern concept of virtual instruments (VIs), using microprocessors and visual interface on video monitors. LabVIEW ® breaks the paradigm of text-based programming language, for programming based on icons. The system will enable the use of this reactor in training and personnel training in the nuclear field. The work follows the recommendations of the International Atomic Energy Agency (IAEA), which has encouraged its members to develop strategic plans in order to use their research reactors. (author)

  2. Operational parameters study of IPR-R1 TRIGA research reactor using virtual instruments

    International Nuclear Information System (INIS)

    Pinto, Antonio Juscelino; Mesquita, Amir Zacarias; Lameiras, Fernando Soares

    2013-01-01

    The instrumentation of nuclear reactors is designed with the principle of reliability, redundancy and diversification of control systems. Reliable monitoring of the parameters involved in the chain reaction is of great importance regarding efficiency and operational safety of the installation. The main goal of the simulation system in this proposed paper is to provide the study and improvement in understanding how these operational variables are interrelated and their behavior especially those related to neutronic and thermohydraulics. The work will be developed using the software LabVIEW ® (Laboratory Virtual Instruments Engineering Workbench). The program will enable the study of the variables involved in the operation of the installation throughout its operating range, for instance, a few mW up to 250 kW. The IPR-R1 TRIGA is a research nuclear reactor placed in open pool and cooled by light water with natural circulation. It is located at the Nuclear Technology Development Center (CDTN), in Belo Horizonte Brazil. The developing system employs the modern concept of virtual instruments (VIs), using microprocessors and visual interface on video monitors. LabVIEW ® breaks the paradigm of text-based programming language, for programming based on icons. The system will enable the use of this reactor in training and personnel training in the nuclear field. The work follows the recommendations of the International Atomic Energy Agency (IAEA), which has encouraged its members to develop strategic plans in order to use their research reactors. (author)

  3. Current status and future role of brain PET/MRI in clinical and research settings

    Energy Technology Data Exchange (ETDEWEB)

    Werner, P.; Barthel, H.; Sabri, O. [University Hospital Leipzig, Department of Nuclear Medicine, Leipzig (Germany); Drzezga, A. [University Hospital Cologne, Department of Nuclear Medicine, Koeln (Germany)

    2015-01-09

    Hybrid PET/MRI systematically offers a complementary combination of two modalities that has often proven itself superior to the single modality approach in the diagnostic work-up of many neurological and psychiatric diseases. Emerging PET tracers, technical advances in multiparametric MRI and obvious workflow advantages may lead to a significant improvement in the diagnosis of dementia disorders, neurooncological diseases, epilepsy and neurovascular diseases using PET/MRI. Moreover, simultaneous PET/MRI is well suited to complex studies of brain function in which fast fluctuations of brain signals (e.g. related to task processing or in response to pharmacological interventions) need to be monitored on multiple levels. Initial simultaneous studies have already demonstrated that these complementary measures of brain function can provide new insights into the functional and structural organization of the brain. (orig.)

  4. Current status and future role of brain PET/MRI in clinical and research settings

    International Nuclear Information System (INIS)

    Werner, P.; Barthel, H.; Sabri, O.; Drzezga, A.

    2015-01-01

    Hybrid PET/MRI systematically offers a complementary combination of two modalities that has often proven itself superior to the single modality approach in the diagnostic work-up of many neurological and psychiatric diseases. Emerging PET tracers, technical advances in multiparametric MRI and obvious workflow advantages may lead to a significant improvement in the diagnosis of dementia disorders, neurooncological diseases, epilepsy and neurovascular diseases using PET/MRI. Moreover, simultaneous PET/MRI is well suited to complex studies of brain function in which fast fluctuations of brain signals (e.g. related to task processing or in response to pharmacological interventions) need to be monitored on multiple levels. Initial simultaneous studies have already demonstrated that these complementary measures of brain function can provide new insights into the functional and structural organization of the brain. (orig.)

  5. The Audit of Principal Effectiveness: Instrumentation for Principalship Research. A Research Project Report.

    Science.gov (United States)

    Valentine, Jerry W.; Bowman, Michael L.

    Using the literature and research on principal effectiveness as a foundation, the Audit of Principal Effectiveness was developed. Initially, 162 items forming 12 theoretical factors describing effective principal behavior were identified and sorted into two documents. The documents, each containing 81 items, were mailed to a total of 3,660…

  6. New customizable phased array UT instrument opens door for furthering research and better industrial implementation

    International Nuclear Information System (INIS)

    Dao, Gavin; Ginzel, Robert

    2014-01-01

    Phased array UT as an inspection technique in itself continues to gain wide acceptance. However, there is much room for improvement in terms of implementation of Phased Array (PA) technology for every unique NDT application across several industries (e.g. oil and petroleum, nuclear and power generation, steel manufacturing, etc.). Having full control of the phased array instrument and customizing a software solution is necessary for more seamless and efficient inspections, from setting the PA parameters, collecting data and reporting, to the final analysis. NDT researchers and academics also need a flexible and open platform to be able to control various aspects of the phased array process. A high performance instrument with advanced PA features, faster data rates, a smaller form factor, and capability to adapt to specific applications, will be discussed

  7. Advanced Instrumentation, Information, and Control Systems Technologies Research in Support of Light Water Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Hallbert, Bruce P.; Kenneth, Thomas [Idaho National Laboratory, Idaho (United States)

    2014-08-15

    The Advanced Instrumentation, Information, and Control (II and C) Systems Technologies Pathway conducts targeted research and development (R and D) to address aging and reliability concerns with the legacy instrumentation and control and related information systems of the U.S. operating light water reactor (LWR) fleet. This work involves two major goals to ensure that legacy analog II and C systems are not life-limiting issues for the LWR fleet, and to implement digital II and C technology in a manner that enables broad innovation and business improvement in the nuclear power plant operating model. Resolving long-term operational concerns with the II and C systems contributes to the long-term sustainability of the LWR fleet, which is vital to the nation's energy and environmental security.

  8. Advanced Instrumentation, Information, and Control Systems Technologies Research in Support of Light Water Reactors

    International Nuclear Information System (INIS)

    Hallbert, Bruce P.; Kenneth, Thomas

    2014-01-01

    The Advanced Instrumentation, Information, and Control (II and C) Systems Technologies Pathway conducts targeted research and development (R and D) to address aging and reliability concerns with the legacy instrumentation and control and related information systems of the U.S. operating light water reactor (LWR) fleet. This work involves two major goals to ensure that legacy analog II and C systems are not life-limiting issues for the LWR fleet, and to implement digital II and C technology in a manner that enables broad innovation and business improvement in the nuclear power plant operating model. Resolving long-term operational concerns with the II and C systems contributes to the long-term sustainability of the LWR fleet, which is vital to the nation's energy and environmental security

  9. New In-pile Instrumentation to Support Fuel Cycle Research and Development

    Energy Technology Data Exchange (ETDEWEB)

    J. Rempe; H. MacLean; R. Schley; D. Hurley; J. Daw; S. Taylor; J. Smith; J. Svoboda; D. Kotter; D. Knudson; M. Guers; S. C. Wilkins

    2011-01-01

    New and enhanced nuclear fuels are a key enabler for new and improved reactor technologies. For example, the goals of the next generation nuclear plant (NGNP) will not be met without irradiations successfully demonstrating the safety and reliability of new fuels. Likewise, fuel reliability has become paramount in ensuring the competitiveness of nuclear power plants. Recently, the Office of Nuclear Energy in the Department of Energy (DOE-NE) launched a new direction in fuel research and development that emphasizes an approach relying on first principle models to develop optimized fuel designs that offer significant improvements over current fuels. To facilitate this approach, high fidelity, real-time, data are essential for characterizing the performance of new fuels during irradiation testing. A three-year strategic research program is proposed for developing the required test vehicles with sensors of unprecedented accuracy and resolution for obtaining the data needed to characterize three-dimensional changes in fuel microstructure during irradiation testing. When implemented, this strategy will yield test capsule designs that are instrumented with new sensor technologies for the Advanced Test Reactor (ATR) and other irradiation locations for the Fuel Cycle Research and Development (FC R&D) program. Prior laboratory testing, and as needed, irradiation testing, of these sensors will have been completed to give sufficient confidence that the irradiation tests will yield the required data. Obtaining these sensors must draw upon the expertise of a wide-range of organizations not currently supporting nuclear fuels research. This document defines this strategic program and provides the necessary background information related to fuel irradiation testing, desired parameters for detection, and an overview of currently available in-pile instrumentation. In addition, candidate sensor technologies are identified in this document, and a list of proposed criteria for ranking

  10. Assessing Student Outcomes of Undergraduate Research with URSSA, the Undergraduate Student Self-Assessment Instrument

    Science.gov (United States)

    Laursen, S. L.; Weston, T. J.; Thiry, H.

    2012-12-01

    URSSA is the Undergraduate Research Student Self-Assessment, an online survey instrument for programs and departments to use in assessing the student outcomes of undergraduate research (UR). URSSA focuses on what students learn from their UR experience, rather than whether they liked it. The online questionnaire includes both multiple-choice and open-ended items that focus on students' gains from undergraduate research. These gains include skills, knowledge, deeper understanding of the intellectual and practical work of science, growth in confidence, changes in identity, and career preparation. Other items probe students' participation in important research-related activities that lead to these gains (e.g. giving presentations, having responsibility for a project). These activities, and the gains themselves, are based in research and thus constitute a core set of items. Using these items as a group helps to align a particular program assessment with research-demonstrated outcomes. Optional items may be used to probe particular features that are augment the research experience (e.g. field trips, career seminars, housing arrangements). The URSSA items are based on extensive, interview-based research and evaluation work on undergraduate research by our group and others. This grounding in research means that URSSA measures what we know to be important about the UR experience The items were tested with students, revised and re-tested. Data from a large pilot sample of over 500 students enabled statistical testing of the items' validity and reliability. Optional items about UR program elements were developed in consultation with UR program developers and leaders. The resulting instrument is flexible. Users begin with a set of core items, then customize their survey with optional items to probe students' experiences of specific program elements. The online instrument is free and easy to use, with numeric results available as raw data, summary statistics, cross-tabs, and

  11. When thin is sexy - neutron reflectometry instrumentation at the Australian replacement research reactor

    International Nuclear Information System (INIS)

    James, M.

    2003-01-01

    Full text: Neutron and X-ray reflectometry are techniques used to probe the structure of surfaces, thin-films or buried interfaces as well as processes occurring at surfaces and interfaces such as adsorption, adhesion and inter-diffusion. Applications cover adsorbed surfactant layers, self-assembled monolayers, biological membranes, electrochemical and catalytic interfaces, polymer coatings and photosensitive films. Contrast variation and selective deuteration of hydrogenous materials are important aspects of the neutron-based technique. Neutron reflectometry probes the structure of materials normal to the surface at depths of up to several thousand Angstroms, with an effective depth resolution of a few Angstroms. Neutron reflectometry experiments have been performed by a number of Australian researchers at overseas facilities for more than a decade, however this capability has previously been absent in this country. A neutron reflectometer has been recognised as one of the highest priority instruments to be constructed at the new 20MW research reactor facility at Lucas Heights (due for completion in 2006). In this presentation we report the design of the time-of-flight reflectometer to be constructed at the new research facility. The reflectometer will operate with a vertical scattering plane and thus be able to measure specular reflectometry from both solid and liquid samples. A series of disc choppers will enable the instrument resolution (ΔQ/Q) to be varied from 2% to > 15%. The detection system will consist of a 2-dimenional position sensitive detector that will also allow the measurement of off-specular reflectivity

  12. Real-Time fMRI in Neuroscience Research and Its Use in Studying the Aging Brain

    Science.gov (United States)

    Rana, Mohit; Varan, Andrew Q.; Davoudi, Anis; Cohen, Ronald A.; Sitaram, Ranganatha; Ebner, Natalie C.

    2016-01-01

    Cognitive decline is a major concern in the aging population. It is normative to experience some deterioration in cognitive abilities with advanced age such as related to memory performance, attention distraction to interference, task switching, and processing speed. However, intact cognitive functioning in old age is important for leading an independent day-to-day life. Thus, studying ways to counteract or delay the onset of cognitive decline in aging is crucial. The literature offers various explanations for the decline in cognitive performance in aging; among those are age-related gray and white matter atrophy, synaptic degeneration, blood flow reduction, neurochemical alterations, and change in connectivity patterns with advanced age. An emerging literature on neurofeedback and Brain Computer Interface (BCI) reports exciting results supporting the benefits of volitional modulation of brain activity on cognition and behavior. Neurofeedback studies based on real-time functional magnetic resonance imaging (rtfMRI) have shown behavioral changes in schizophrenia and behavioral benefits in nicotine addiction. This article integrates research on cognitive and brain aging with evidence of brain and behavioral modification due to rtfMRI neurofeedback. We offer a state-of-the-art description of the rtfMRI technique with an eye towards its application in aging. We present preliminary results of a feasibility study exploring the possibility of using rtfMRI to train older adults to volitionally control brain activity. Based on these first findings, we discuss possible implementations of rtfMRI neurofeedback as a novel technique to study and alleviate cognitive decline in healthy and pathological aging. PMID:27803662

  13. Food-related lifestyles in Singapore: Preliminary testing of a Western European research instrument in Southeast Asia

    DEFF Research Database (Denmark)

    Askegaard, Søren; Brunsø, Karen

    1999-01-01

    The food-related lifestyle instrument developed by the MAPP research group has, up till now, been applied mainly in the context of European cultures. The purpose of the present study is to apply the food-related life style instrument in a new and very different cultural setting, to compare result...

  14. Research progress of BOLD-fMRI in minimal hepatic encephalopathy

    International Nuclear Information System (INIS)

    Zhou Zhiming; Zhao Jiannong

    2013-01-01

    The minimal hepatic encephalopathy is the early stage of hepatic encephalopathy. It has few apparent clinical symptoms and specific manifestations, and is difficult to diagnose. In the recent years, BOLD-fMRI has been used to study hepatic encephalopathy gradually. Through detection of the brain neuron activities in different states, it can not only locate the abnormal activity of brain functional areas, but also can find the changes of brain functional connectivity. BOLD- fMRI combining with other MR technologies can explore the pathology and pathogenesis of minimal hepatic encephalopathy from micro to macro and from structure to function. (authors)

  15. Evaluation applications of instrument calibration research findings in psychology for very small samples

    Science.gov (United States)

    Fisher, W. P., Jr.; Petry, P.

    2016-11-01

    Many published research studies document item calibration invariance across samples using Rasch's probabilistic models for measurement. A new approach to outcomes evaluation for very small samples was employed for two workshop series focused on stress reduction and joyful living conducted for health system employees and caregivers since 2012. Rasch-calibrated self-report instruments measuring depression, anxiety and stress, and the joyful living effects of mindfulness behaviors were identified in peer-reviewed journal articles. Items from one instrument were modified for use with a US population, other items were simplified, and some new items were written. Participants provided ratings of their depression, anxiety and stress, and the effects of their mindfulness behaviors before and after each workshop series. The numbers of participants providing both pre- and post-workshop data were low (16 and 14). Analysis of these small data sets produce results showing that, with some exceptions, the item hierarchies defining the constructs retained the same invariant profiles they had exhibited in the published research (correlations (not disattenuated) range from 0.85 to 0.96). In addition, comparisons of the pre- and post-workshop measures for the three constructs showed substantively and statistically significant changes. Implications for program evaluation comparisons, quality improvement efforts, and the organization of communications concerning outcomes in clinical fields are explored.

  16. Materials and Life Science Experimental Facility (MLF at the Japan Proton Accelerator Research Complex II: Neutron Scattering Instruments

    Directory of Open Access Journals (Sweden)

    Kenji Nakajima

    2017-11-01

    Full Text Available The neutron instruments suite, installed at the spallation neutron source of the Materials and Life Science Experimental Facility (MLF at the Japan Proton Accelerator Research Complex (J-PARC, is reviewed. MLF has 23 neutron beam ports and 21 instruments are in operation for user programs or are under commissioning. A unique and challenging instrumental suite in MLF has been realized via combination of a high-performance neutron source, optimized for neutron scattering, and unique instruments using cutting-edge technologies. All instruments are/will serve in world-leading investigations in a broad range of fields, from fundamental physics to industrial applications. In this review, overviews, characteristic features, and typical applications of the individual instruments are mentioned.

  17. An automated calibration laboratory for flight research instrumentation: Requirements and a proposed design approach

    Science.gov (United States)

    Oneill-Rood, Nora; Glover, Richard D.

    1990-01-01

    NASA's Dryden Flight Research Facility (Ames-Dryden), operates a diverse fleet of research aircraft which are heavily instrumented to provide both real time data for in-flight monitoring and recorded data for postflight analysis. Ames-Dryden's existing automated calibration (AUTOCAL) laboratory is a computerized facility which tests aircraft sensors to certify accuracy for anticipated harsh flight environments. Recently, a major AUTOCAL lab upgrade was initiated; the goal of this modernization is to enhance productivity and improve configuration management for both software and test data. The new system will have multiple testing stations employing distributed processing linked by a local area network to a centralized database. The baseline requirements for the new AUTOCAL lab and the design approach being taken for its mechanization are described.

  18. Cochlear implant with a non-removable magnet: preliminary research at 3-T MRI.

    Science.gov (United States)

    Dubrulle, F; Sufana Iancu, A; Vincent, C; Tourrel, G; Ernst, O

    2013-06-01

    To perform preliminary tests in vitro and with healthy volunteers to determine the 3-T MRI compatibility of a cochlear implant with a non-removable magnet. In the in vitro phase, we tested six implants for temperature changes and internal malfunctioning. We measured the demagnetisation of 65 internal magnets with different tilt angles between the implant's magnetic field (bi) and the main magnetic field (b0). In the in vivo phase, we tested 28 operational implants attached to the scalps of volunteers with the head in three different positions. The study did not find significant temperature changes or electronic malfunction in the implants tested in vitro. We found considerable demagnetisation of the cochlear implant magnets in the in vitro and in vivo testing influenced by the position of the magnet in the main magnetic field. We found that if the bi/b0 angle is 90°, there is demagnetisation in almost 60 % of the cases. When the angle is around 90°, the risk of demagnetisation is low (6.6 %). The preliminary results on cochlear implants with non-removable magnets indicate the need to maintain the contraindication of passage through 3-T MRI. • Magnetic resonance imaging can affect cochlear implants and vice versa. • Demagnetisation of cochlear implant correlates with the angle between bi and b0. • The position of the head in the MRI influences the demagnetisation. • Three-Tesla MRI for cochlear implants is still contraindicated. • However some future solutions are discussed.

  19. Translations of Developmental Screening Instruments: An Evidence Map of Available Research.

    Science.gov (United States)

    El-Behadli, Ana F; Neger, Emily N; Perrin, Ellen C; Sheldrick, R Christopher

    2015-01-01

    Children whose parents do not speak English experience significant disparities in the identification of developmental delays and disorders; however, little is known about the availability and validity of translations of developmental screeners. The goal was to create a map of the scientific evidence regarding translations of the 9 Academy of Pediatrics-recommended screening instruments into languages other than English. The authors conducted a systematic search of Medline and PsycINFO, references of identified articles, publishers' Web sites, and official manuals. Through evidence mapping, a new methodology supported by AHRQ and the Cochrane Collaboration, the authors documented the extent and distribution of published evidence supporting translations of developmental screeners. Data extraction focused on 3 steps of the translation and validation process: (1) translation methods used, (2) collection of normative data in the target language, and (3) evidence for reliability and validity. The authors identified 63 distinct translations among the 9 screeners, of which 44 had supporting evidence published in peer-reviewed sources. Of the 63 translations, 35 had at least some published evidence regarding translation methods used, 28 involving normative data, and 32 regarding reliability and/or construct validity. One-third of the translations found were of the Denver Developmental Screening Test. Specific methods used varied greatly across screeners, as did the level of detail with which results were reported. Few developmental screeners have been translated into many languages. Evidence map of the authors demonstrates considerable variation in both the amount and the comprehensiveness of information available about translated instruments. Informal guidelines exist for conducting translation of psychometric instruments but not for documentation of this process. The authors propose that uniform guidelines be established for reporting translation research in peer

  20. Cultural adaptation and validation of an instrument on barriers for the use of research results.

    Science.gov (United States)

    Ferreira, Maria Beatriz Guimarães; Haas, Vanderlei José; Dantas, Rosana Aparecida Spadoti; Felix, Márcia Marques Dos Santos; Galvão, Cristina Maria

    2017-03-02

    to culturally adapt The Barriers to Research Utilization Scale and to analyze the metric validity and reliability properties of its Brazilian Portuguese version. methodological research conducted by means of the cultural adaptation process (translation and back-translation), face and content validity, construct validity (dimensionality and known groups) and reliability analysis (internal consistency and test-retest). The sample consisted of 335 nurses, of whom 43 participated in the retest phase. the validity of the adapted version of the instrument was confirmed. The scale investigates the barriers for the use of the research results in clinical practice. Confirmatory factorial analysis demonstrated that the Brazilian Portuguese version of the instrument is adequately adjusted to the dimensional structure the scale authors originally proposed. Statistically significant differences were observed among the nurses holding a Master's or Doctoral degree, with characteristics favorable to Evidence-Based Practice, and working at an institution with an organizational cultural that targets this approach. The reliability showed a strong correlation (r ranging between 0.77 and 0.84, pcultura organizacional dirigida hacia tal aproximación. La fiabilidad presentó correlación fuerte (r variando entre 0,77 y 0,84, pcultura organizacional direcionada para tal abordagem. A confiabilidade apresentou correlação forte (r variando entre 0,77e 0,84, p<0,001) e a consistência interna foi adequada (alfa de Cronbach variando entre 0,77 e 0,82) . a versão para o português brasileiro do instrumento The Barriers Scale demonstrou-se válida e confiável no grupo estudado.

  1. Modernization of Safety and Control Instrumentation of the IEA-R1 Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    De Carvalho, P.V., E-mail: paulov@ien.gov.br [Institute of Nuclear Engineering (IEN), National Nuclear Energy Commission (CNEN), Rio de Janeiro (Brazil)

    2014-08-15

    The research reactor IEA-R1 located in the Institute of Energy and Nuclear Research (IPEN), São Paulo, Brazil, obtained its first criticality on 16 September 1957 and since then has served the scientific and medical community in the performance of experiments in applied nuclear physics, as well as the provision of radioisotopes for production of radiopharmaceuticals. The reactor produces radioisotopes {sup 82}Br and {sup 41}Ar for special processes in industrial inspection and {sup 192}Ir and {sup 198}Au as sources of radiation used in brachytherapy, {sup 153}Sm for pain relief in patients with bone metastasis, and calibrated sources of {sup 133}Ba, {sup 137}Cs, {sup 57}Co, {sup 60}Co, {sup 241}Am and {sup 152}Eu used in medical clinics and hospitals practicing nuclear medicine and research laboratories. Services are offered in regular non-destructive testing by neutron radiography, neutron irradiation of silicon for phosphorous doping and other various irradiations with neutrons. The reactor is responsible for producing approximately 70% of radiopharmaceutical {sup 131}I used in Brazil, which saves about US$ 800 000 annually for the country. After more than 50 years of use, most of its equipment and systems have been modernized, and recently the reactor power was increased to 5 MW in order to enhance radioisotope production capability. However, the control room and nuclear instrumentation system used for reactor safety have operated more than 30 years and require constant maintenance. Many equipment and electronic components are obsolete, and replacements are not available in the market. The modernization of the nuclear safety and control instrumentation systems of IEA-R1 is being carried out with consideration for the internationally recognized criteria for safety and reliable reactor operations and the latest developments in nuclear electronic technology. The project for the new reactor instrumentation system specifies three wide range neutron monitoring

  2. Regulatory Research of the PWR Severe Accident. Information Needs and Instrumentation for Hydrogen Control and Management

    International Nuclear Information System (INIS)

    Park, Gun Chul; Suh, Kune Y.; Lee, Jin Yong; Lee, Seung Dong

    2001-03-01

    The current research is concerned with generation of basic engineering data needed in the process of developing hydrogen control guidelines as part of accident management strategies for domestic nuclear power plants and formulating pertinent regulatory requirements. Major focus is placed on identification of information needs and instrumentation methods for hydrogen control and management in the primary system and in the containment, development of decision-making trees for hydrogen management and their quantification, the instrument availability under severe accident conditions, critical review of relevant hydrogen generation model and phenomena In relation to hydrogen behavior, we analyzed the severe accident related hydrogen generation in the UCN 3·4 PWR with modified hydrogen generation model. On the basis of the hydrogen mixing experiment and related GASFLOW calculation, the necessity of 3-dimensional analysis of the hydrogen mixing was investigated. We examined the hydrogen control models related to the PAR(Passive Autocatalytic Recombiner) and performed MAAP4 calculation in relation to the decision tree to estimate the capability and the role of the PAR during a severe accident

  3. Regulatory Research of the PWR Severe Accident. Information Needs and Instrumentation for Hydrogen Control and Management

    Energy Technology Data Exchange (ETDEWEB)

    Park, Gun Chul; Suh, Kune Y.; Lee, Jin Yong; Lee, Seung Dong [Seoul Nat' l Univ., Seoul (Korea, Republic of)

    2001-03-15

    The current research is concerned with generation of basic engineering data needed in the process of developing hydrogen control guidelines as part of accident management strategies for domestic nuclear power plants and formulating pertinent regulatory requirements. Major focus is placed on identification of information needs and instrumentation methods for hydrogen control and management in the primary system and in the containment, development of decision-making trees for hydrogen management and their quantification, the instrument availability under severe accident conditions, critical review of relevant hydrogen generation model and phenomena In relation to hydrogen behavior, we analyzed the severe accident related hydrogen generation in the UCN 3{center_dot}4 PWR with modified hydrogen generation model. On the basis of the hydrogen mixing experiment and related GASFLOW calculation, the necessity of 3-dimensional analysis of the hydrogen mixing was investigated. We examined the hydrogen control models related to the PAR(Passive Autocatalytic Recombiner) and performed MAAP4 calculation in relation to the decision tree to estimate the capability and the role of the PAR during a severe accident.

  4. Methods and instrumentation for investigating Hall sensors during their irradiation in nuclear research reactors

    International Nuclear Information System (INIS)

    Bolshakova, I.; Holyaka, R.; Makido, E.; Marusenkov, A.; Shurygin, F.; Yerashok, V.; Moreau, P. J.; Vayakis, G.; Duran, I.; Stockel, J.; Chekanov, V.; Konopleva, R.; Nazarkin, I.; Kulikov, S.; Leroy, C.

    2009-01-01

    Present work discusses the issues of creating the instrumentation for testing the semiconductor magnetic field sensors during their irradiation with neutrons in nuclear reactors up to fluences similar to neutron fluences in steady-state sensor locations in ITER. The novelty of the work consists in Hall sensor parameters being investigated: first, directly during the irradiation (in real time), and, second, at high irradiation levels (fast neutron fluence > 10 18 n/cm 2 ). Developed instrumentation has been successfully tested and applied in the research experiments on radiation stability of magnetic sensors in IBR-2 (JINR, Dubna) and VVR-M (PNPI, Saint-Petersburg) reactors. The 'Remote-Rad' bench consists of 2 heads (head 1 and head 2) bearing investigated sensors put in a ceramic setting, of electronic unit, of personal computer and of signal lines. Each head contains 6 Hall sensors and a coil for generating test magnetic field. Moreover head 1 contains thermocouples for temperature measurement while the temperature of head 2 is measured by thermo-resistive method. The heads are placed in the reactor channel

  5. Report of the 2. research co-ordination meeting of the co-ordinated research programme on the development of computer-based troubleshooting tools and instruments

    International Nuclear Information System (INIS)

    1998-11-01

    The Research coordination meeting reviewed current results on the Development of Computer-Based Troubleshooting Tools and Instruments. Presentations at the meeting were made by the participants, and the project summary reports include: PC based software for troubleshooting microprocessor-based instruments; technical data base software; design and construction of a random pulser for maintenance and quality control of a nuclear counting system; microprocessor-based power conditioner; in-circuit emulator for microprocessor-based nuclear instruments; PC-based analog signal generator for simulated detector signals and arbitrary test waveforms for testing of nuclear instruments; expert system for nuclear instrument troubleshooting; development and application of versatile computer-based measurement and diagnostic tools; and development of a programmable signal generator for troubleshooting of nuclear instrumentation

  6. Safety Research Experiment Facility Project. Conceptual design report. Volume VIII. Instrumentation and control

    International Nuclear Information System (INIS)

    1975-01-01

    Included are sections dealing with the following: nuclear instrumentation system, reactor control system, plant protection system, plant annunciator system, data acquisition system, and reactor cooling system instrumentation and control

  7. Review of regulatory requirements relevant to calibration of monitoring instruments in research reactors

    Energy Technology Data Exchange (ETDEWEB)

    Gomaa, Hassan; Khedr, Ahmed; El-Din Talha, Kamal [Egyptian Nuclear and Radiological Regulatory Authority, Cairo (Egypt). Nuclear Safety Engineering Dept.

    2015-05-15

    The objective of this work is to demonstrate the regulatory requirements pertaining to calibration of monitoring instruments in research reactors. The regulatory statements concerning this subject in IAEA safety standards and the implementation of such regulations in twelve countries with different levels of nuclear programs are surveyed: Australia, Bulgaria, Canada, Egypt, Finland, Germany, Hungary, Slovenia, South Korea, Spain, United Kingdom of England and United States of America. In addition, the requirements of ISO/IEC17025 and NUPIC (Nuclear Utilities Procurement Issues Committee) are compared. Seven technical and administrate aspects are suggested as the comparison criteria and the explicit expression of the statements, the level of document (i.e.: act, requirement or guide) are the considered resources. The main differences and similarities between the different approaches are identified in order to provide an input for future development of the national regulations.

  8. Clinical research on alterations of brain MRI and 1H-MRS in chronic hepatic disease

    International Nuclear Information System (INIS)

    Long Liling; Li Xiangrong; Hong Zhongkui

    2006-01-01

    Objective: To study the abnormal findings and metabolic alterations of the brain in chronic hepatic disease with MRI and 1 H magnetic resonance spectroscopy ( 1 H-MRS) for better understanding the clinical significance of pallidal hyperintensity and the role in the diagnosis and treatment of hepatic encephalopathy (HE). Methods: Brain MRI and 1 H-MRS examination were performed in 50 patients with chronic hepatic disease and 20 healthy volunteers. The pallidus index (PI) was calculated and the height of resonance peaks of Glx was measured. The correlation between PI and Child/Pugh classification, and the association between blood ammonia and the spectroscopic alterations were studied. Pre-and post-therapeutic comparative study was also conducted in 5 cases with chronic HE. Results: PI was gradually increased from healthy volunteers to patients with chronic hepatitis and liver cirrhosis (1.01± 0.04, 1.06±0.09, and 1.18±0.09), and the differences in PI value among them were significant (F=22.294, P 1 -weighted MRI disappeared and the abnormal metabolic alterations returned to normal range 5 to 6 months after successful liver transplantation. However, the normalization of 1 H-MRS alterations preceded the disappearance of pallidal hyperintensities. Conclusion: PI can be an index of reference for liver dysfunction. Glx is more sensitive than blood ammonia in detecting the brain dysfunction. MRI and 1 H-MRS are reliable techniques in the diagnosis and evaluation of therapy for hepatic encephalopathy. (authors)

  9. Assessing research activity and capacity of community-based organizations: development and pilot testing of an instrument.

    Science.gov (United States)

    Humphries, Debbie L; Carroll-Scott, Amy; Mitchell, Leif; Tian, Terry; Choudhury, Shonali; Fiellin, David A

    2014-01-01

    Although awareness of the importance of the research capacity of community-based organizations (CBOs) is growing, a uniform framework of the research capacity domains within CBOs has not yet been developed. To develop a framework and instrument (the Community REsearch Activity assessment Tool [CREAT]) for assessing the research activity and capacity of CBOs that incorporates awareness of the different data collection and analysis priorities of CBOs. We conducted a review of existing tools for assessing research capacity to identify key capacity domains. Instrument items were developed through an iterative process with CBO representatives and community researchers. The CREAT was then pilot tested with 30 CBOs. The four primary domains of the CREAT framework include 1) organizational support for research, 2) generalizable experiences, 3) research specific experiences, and 4) funding. Organizations reported a high prevalence of activities in the research-specific experiences domain, including conducting literature reviews (70%), use of research terminology (83%), and primary data collection (100%). Respondents see research findings as important to improve program and service delivery, and to seek funds for new programs and services. Funders, board members, and policymakers are the most important dissemination audiences. The work reported herein advances the field of CBO research capacity by developing a systematic framework for assessing research activity and capacity relevant to the work of CBOs, and by developing and piloting an instrument to assess activity in these domains.

  10. Applications of instrumental neutron activation analysis in the Analytical Division of the Research Center Juelich (KFA)

    International Nuclear Information System (INIS)

    Erdtmann, G.

    1991-12-01

    The Radioanalytical Chemistry Section, as a part of the Central Division of Chemical Analysis of the Research Center KFA Juelich, has the task to provide and to apply nuclear methods in the analytical service for the institutes and projects of the KFA and to customers outside. A great part of this service is trace element determinations by neutron activation analysis using the research reactor FRJ-2. The procedure for the instrumental technique is described and mainly practical aspects are reported in detail. It is based on the k 0 -method developed by Simonits and DeCorte. The results are calculated from the peak areas of the γ-lines and the corresponding k 0 -factors. A new variant of this procedure is required, if the program used for the deconvolution of the γ-spectra provides absolute decay rates of the radionuclides instead of the γ-emission rates. This variant is also described. Some examples of analyses carried out in the analytical service are presented and discussed mainly with respect to accuracy of the results and detection limits. (orig.) [de

  11. Instrument Adaptation in Cross-Cultural Studies of Students' Mathematics-Related Beliefs: Learning from Healthcare Research

    Science.gov (United States)

    Andrews, Paul; Diego-Mantecón, Jose

    2015-01-01

    Much comparative research into education-related beliefs has exploited questionnaires developed in one culture for use in another. This has been particularly the case in mathematics education, the focus of this paper. In so doing, researchers have tended to assume that translation alone is sufficient to warrant a reliable and valid instrument for…

  12. Upward Transfer in STEM Fields of Study: A New Conceptual Framework and Survey Instrument for Institutional Research

    Science.gov (United States)

    Wang, Xueli

    2016-01-01

    This chapter describes a new conceptual framework that informs research on factors influencing transfer in STEM fields of study from 2-year to 4-year institutions, presents a new survey instrument based on the framework, and offers directions for future research in this area.

  13. Measuring spirituality and religiosity in clinical research: a systematic review of instruments available in the Portuguese language.

    Science.gov (United States)

    Lucchetti, Giancarlo; Lucchetti, Alessandra Lamas Granero; Vallada, Homero

    2013-01-01

    Despite numerous spirituality and/or religiosity (S/R) measurement tools for use in research worldwide, there is little information on S/R instruments in the Portuguese language. The aim of the present study was to map out the S/R scales available for research in the Portuguese language. Systematic review of studies found in databases. A systematic review was conducted in three phases. Phases 1 and 2: articles in Portuguese, Spanish and English, published up to November 2011, dealing with the Portuguese translation and/or validation of S/R measurement tools for clinical research, were selected from six databases. Phase 3: the instruments were grouped according to authorship, cross-cultural adaptation, internal consistency, concurrent and discriminative validity and test-retest procedures. Twenty instruments were found. Forty-five percent of these evaluated religiosity, 40% spirituality, 10% religious/spiritual coping and 5% S/R. Among these, 90% had been produced in (n = 3) or translated to (n = 15) Brazilian Portuguese and two (10%) solely to European Portuguese. Nevertheless, the majority of the instruments had not undergone in-depth psychometric analysis. Only 40% of the instruments presented concurrent validity, 45% discriminative validity and 15% a test-retest procedure. The characteristics of each instrument were analyzed separately, yielding advantages, disadvantages and psychometric properties. Currently, 20 instruments for measuring S/R are available in the Portuguese language. Most have been translated (n = 15) or developed (n = 3) in Brazil and present good internal consistency. Nevertheless, few instruments have been assessed regarding all their psychometric qualities.

  14. Measuring spirituality and religiosity in clinical research: a systematic review of instruments available in the Portuguese language

    Directory of Open Access Journals (Sweden)

    Giancarlo Lucchetti

    Full Text Available CONTEXT AND OBJECTIVES Despite numerous spirituality and/or religiosity (S/R measurement tools for use in research worldwide, there is little information on S/R instruments in the Portuguese language. The aim of the present study was to map out the S/R scales available for research in the Portuguese language. DESIGN AND SETTING Systematic review of studies found in databases. METHODS A systematic review was conducted in three phases. Phases 1 and 2: articles in Portuguese, Spanish and English, published up to November 2011, dealing with the Portuguese translation and/or validation of S/R measurement tools for clinical research, were selected from six databases. Phase 3: the instruments were grouped according to authorship, cross-cultural adaptation, internal consistency, concurrent and discriminative validity and test-retest procedures. RESULTS Twenty instruments were found. Forty-five percent of these evaluated religiosity, 40% spirituality, 10% religious/spiritual coping and 5% S/R. Among these, 90% had been produced in (n = 3 or translated to (n = 15 Brazilian Portuguese and two (10% solely to European Portuguese. Nevertheless, the majority of the instruments had not undergone in-depth psychometric analysis. Only 40% of the instruments presented concurrent validity, 45% discriminative validity and 15% a test-retest procedure. The characteristics of each instrument were analyzed separately, yielding advantages, disadvantages and psychometric properties. CONCLUSION Currently, 20 instruments for measuring S/R are available in the Portuguese language. Most have been translated (n = 15 or developed (n = 3 in Brazil and present good internal consistency. Nevertheless, few instruments have been assessed regarding all their psychometric qualities.

  15. Geosciences research: development of techniques and instruments for investigation geological environments

    International Nuclear Information System (INIS)

    1993-01-01

    In order to understand the geological environment in Japan, new investigation techniques have been developed. These include: 1) Geological techniques for fracture characterization, 2) Nondestructive investigation techniques for detailed geological structure, 3) Instruments for hydraulic characterization, 4) Instruments for hydrochemical characterization. Results so far obtained are: 1) Fractures can be classified by their patterns, 2) The applicability and limitations of conventional geophysical methods were defined, 3) Instruments for measuring very low permeability were successfully developed, 4) Instruments for sampling formation water without changing in-situ conditions were developed. (author)

  16. Application of micro-PIXE, MRI and light microscopy for research in wood science and dendroecology

    International Nuclear Information System (INIS)

    Merela, M.; Pelicon, P.; Vavpetic, P.; Regvar, M.; Vogel-Mikus, K.; Sersa, I.; Policnik, H.; Pokorny, B.; Levanic, T.; Oven, P.

    2009-01-01

    Beech (Fagus sylvatica L.) branches were topped and after five months the wound response was analyzed by PIXE, 3D-MRI and light microscopy. From freshly cut and deeply frozen sample 30 μm thick longitudinal-radial tissue sections were prepared for anatomical investigations and micro-PIXE analysis. Light microscopy revealed the structural response to wounding, i.e. occurrence of the reaction zone between the exposed and dehydrated dead tissue and healthy sound wood. The reaction zone was characterized by tylosis in vessels and accumulation of colored deposits in parenchyma cells, fibres and vessels. 3D MRI of a parallel sample showed that the moisture content in the reaction zone was three times higher than in normal healthy wood. Micro-PIXE mapping at margins of compromised wood in beech revealed an increased concentration of potassium in the reaction zone. The increase in the calcium concentration was associated with the dehydrated tissue adjacent to reaction zones. In addition, micro-PIXE was used to determine the elemental distribution in annual tree rings. This may be relevant for retrospective assessment of environmental pollution in wood by measuring yearly increments as a biomonitoring tool. The analysis of European larch (Larix decidua Mill.) wood revealed a high similarity between optical characteristics (i.e. late versus earlywood) and elemental (e.g. Cl, K, Ca, Mn, Zn) distribution.

  17. Inexperienced clinicians can extract pathoanatomic information from MRI narrative reports with high reproducability for use in research/quality assurance

    DEFF Research Database (Denmark)

    Kent, Peter; Briggs, Andrew M; Albert, Hanne Birgit

    2011-01-01

    Background Although reproducibility in reading MRI images amongst radiologists and clinicians has been studied previously, no studies have examined the reproducibility of inexperienced clinicians in extracting pathoanatomic information from magnetic resonance imaging (MRI) narrative reports and t...

  18. On use of ZPR research reactors and associated instrumentation and measurement methods for reactor physics studies

    Energy Technology Data Exchange (ETDEWEB)

    Chauvin, J.P. [CEA,DEN, DER, SPEX, Experimental Physics Service, Cadarache, F-13108 St-Paul-Lez-Durance (France); Blaise, P. [CEA, DEN, DER, SPEX Experimental Programs Laboratory, Cadarache, F-13108 St-Paul-Lez-Durance (France); Lyoussi, A. [CEA, DEN, DER, Instrumentation Sensors and Dosimetry Laboratory, Cadarache, F-13108 St-Paul-Lez-Durance (France)

    2015-07-01

    The French atomic and alternative energies -CEA- is strongly involved in research and development programs concerning the use of nuclear energy as a clean and reliable source of energy and consequently is working on the present and future generation of reactors on various topics such as ageing plant management, optimization of the plutonium stockpile, waste management and innovative systems exploration. Core physics studies are an essential part of this comprehensive R and D effort. In particular, the Zero Power Reactor (ZPR) of CEA: EOLE, MINERVE and MASURCA play an important role in the validation of neutron (as well photon) physics calculation tools (codes and nuclear data). The experimental programs defined in the CEA's ZPR facilities aim at improving the calculation routes by reducing the uncertainties of the experimental databases. They also provide accurate data on innovative systems in terms of new materials (moderating and decoupling materials) and new concepts (ADS, ABWR, new MTR (e.g. JHR), GENIV) involving new fuels, absorbers and coolant materials. Conducting such interesting experimental R and D programs is based on determining and measuring main parameters of phenomena of interest to qualify calculation tools and nuclear data 'libraries'. Determining these parameters relies on the use of numerous and different experimental techniques using specific and appropriate instrumentation and detection tools. Main ZPR experimental programs at CEA, their objectives and challenges will be presented and discussed. Future development and perspectives regarding ZPR reactors and associated programs will be also presented. (authors)

  19. Underground Research Laboratory room 209 instrument array. Vol. 1,2

    International Nuclear Information System (INIS)

    Lang, P.A.; Kuzyk, G.W.; Babulic, P.J.; Bilinsky, D.M.; Everitt, R.A.; Spinney, M.H.; Kozak, E.T.; Davison, C.C.

    1991-06-01

    An in situ excavation response test was conducted at the 240 Level of the Underground Research Laboratory (URL). The test was carried out in conjunction with the drill-and-blast excavation of a near-circular tunnel (Room 209), about 3.5 m in diameter. The tunnel was excavated through a tunnel axis. Three modelling groups made predictions of the response of the rock mass and hydraulic behaviour of the water-bearing fracture to excavation. The tunnel was excavated in two stages, a pilot tunnel followed by a slash, providing two complete sets of response measurements. Careful excavation was carried out to ensure the excavation shape after each blast round agreed closely with the planned shape incorporated in the numerical models. Instrumentation installed before the tunnel was extended monitored the complete strain tensor at eight locations around the tunnel, radial displacements and piezometric pressures at nine locations in the fracture. As well, tunnel convergence, water flows from the fracture, and hydraulic conductivity of the fracture at nine locations, were measured after each excavation step. The final tunnel profiles were accurately surveyed, and the geology was mapped in detail. The results are presented in this report for comparison with the modellers' predictions (reported in AECL--9566-2). Some preliminary conclusions and recommendations regarding the field testing are presented

  20. Culture and ethnicity influence outcomes of the Scoliosis Research Society Instrument in adolescent idiopathic scoliosis.

    Science.gov (United States)

    Morse, Lee Jae; Kawakami, Noriaki; Lenke, Lawrence G; Sucato, Daniel J; Sanders, James O; Diab, Mohammad

    2012-05-20

    Retrospective comparative study. To report preoperative differences in the Scoliosis Research Society Outcomes Instrument (SRS-30) between multiple US ethnicities and native Japanese and Korean children with adolescent idiopathic scoliosis (AIS). The SRS-24 was developed in a US cohort with AIS. Comparative studies using the SRS-24 between US and Japanese patients showed differences, suggesting that culture might affect functional outcome. Preoperative SRS-30 outcomes were collected from 1853 children with AIS from 6 different ethnic groups: US white (1234), black (213), Hispanic (78), and Asian (29), as well as native Japanese (192) and Koreans (107). Analysis of covariance of 4 SRS-30 domains (pain, appearance, activity, and mental) was compared between groups adjusting for differences in age, sex, major curve magnitude, and body mass index. Pairwise comparisons of the 4 SRS-30 domains were adjusted for multiple comparisons, using Bonferroni correction. A P value of less than 0.05 was considered significant. Significant differences between ethnicities were found in all domains (P Culture and ethnicity influence SRS-30 outcomes in AIS. Whites reported more pain than Japanese and Koreans. Japanese and Koreans had the lowest appearance scores. Koreans additionally were distinguished by the lowest activity, mental, and total scores. These cultural and ethnic differences must be taken into account when counseling patients with AIS and studying functional outcomes.

  1. Research on a new oral contrast agent for abdominal MRI using free manganese ion

    International Nuclear Information System (INIS)

    Hasegawa, Hideo; Fujita, Osamu; Hiraishi, Kumiko; Narabayashi, Isamu; Komba, Toshinori; Hamamura, Yoshinori.

    1996-01-01

    Manganese chloride (Mn: 3 mg/100 g) aqueous solution with hydragenated oligosaccharide and xanthan gum (T 1 : 0.1 sec, T 2 : 0.03 sec at 0.5T) functions in gut as a positive contrast agent on MR T 1 -weighted images and a low signal component on MR T 2 -weighted images. The manganese in the solution functions as a contrast agent under free manganese ion (Mn 2+ ). Further, the solution has special characteristics in terms of MRI signal intensity and relaxation time that are equal to those of blueberry juice, which performs as an effective contrast agent on T 1 -and T 2 -weighted images, and functions as a contrast agent in vitro and in vivo. (author)

  2. Neuropsychopharmacology of auditory hallucinations: insights from pharmacological functional MRI and perspectives for future research.

    Science.gov (United States)

    Johnsen, Erik; Hugdahl, Kenneth; Fusar-Poli, Paolo; Kroken, Rune A; Kompus, Kristiina

    2013-01-01

    Experiencing auditory verbal hallucinations is a prominent symptom in schizophrenia that also occurs in subjects at enhanced risk for psychosis and in the general population. Drug treatment of auditory hallucinations is challenging, because the current understanding is limited with respect to the neural mechanisms involved, as well as how CNS drugs, such as antipsychotics, influence the subjective experience and neurophysiology of hallucinations. In this article, the authors review studies of the effect of antipsychotic medication on brain activation as measured with functional MRI in patients with auditory verbal hallucinations. First, the authors examine the neural correlates of ongoing auditory hallucinations. Then, the authors critically discuss studies addressing the antipsychotic effect on the neural correlates of complex cognitive tasks. Current evidence suggests that blood oxygen level-dependant effects of antipsychotic drugs reflect specific, regional effects but studies on the neuropharmacology of auditory hallucinations are scarce. Future directions for pharmacological neuroimaging of auditory hallucinations are discussed.

  3. Research for correction pre-operative MRI images of brain during operation using particle method simulation

    International Nuclear Information System (INIS)

    Shino, Ryosaku; Koshizuka, Seiichi; Sakai, Mikio; Ito, Hirotaka; Iseki, Hiroshi; Muragaki, Yoshihiro

    2010-01-01

    In the neurosurgical procedures, surgeon formulates a surgery plan based on pre-operative images such as MRI. However, the brain is transformed by removal of the affected area. In this paper, we propose a method for reconstructing pre-operative images involving the deformation with physical simulation. First, the domain of brain is identified in pre-operative images. Second, we create particles for physical simulation. Then, we carry out the linear elastic simulation taking into account the gravity. Finally, we reconstruct pre-operative images with deformation according to movement of the particles. We show the effectiveness of this method by reconstructing the pre-operative image actually taken before surgery. (author)

  4. [Construction and validation of the "La Salle Instrument" to evaluate the ethical aspects in biomedical research on human beings].

    Science.gov (United States)

    Valdivia-Gómez, Gilberto Guzmán; Velasco-Jiménez, María Teresa; Domínguez-González, Alejandro; Meneses-Ruíz, Dulce María; Padilla-García, Raúl Amauri

    2017-01-01

    Research projects must demonstrate not only a rigorous scientific methodology, but also the ethical aspects that require profound reflection of the reviewers. Current regulations establish criteria for research projects on human health, but many of these aspects are subjective. How can the evaluation of such projects be standardized? This is the main subject of the current project. This project comprises two phases. First, the design and construction of an instrument of evaluation based on the fundamental principles of bioethics, which are autonomy, beneficence, non-maleficence, and justice, and other aspects. The second phase consists of content validation through expert. During the phase of reviewing the instrument, it was necessary to make changes by adding, removing, or changing the concepts or criteria, which lead to the construction of the second version of the format. This new instrument was reviewed and analyzed by using the AGREE II instrument, and this version was validated by experts by greater than 95%. There are some recommendations to analyze the ethical aspects in research protocols involving human subjects, but they define the concepts and criteria to be evaluated. By presenting the criteria to be evaluated individually, the "La Salle instrument" allows the evaluation to be more objective and standardized.

  5. Academic Research Equipment in the Physical and Computer Sciences and Engineering. An Analysis of Findings from Phase I of the National Science Foundation's National Survey of Academic Research Instruments and Instrumentation Needs.

    Science.gov (United States)

    Burgdorf, Kenneth; White, Kristine

    This report presents information from phase I of a survey designed to develop quantitative indicators of the current national stock, cost/investment, condition, obsolescence, utilization, and need for major research instruments in academic settings. Data for phase I (which focused on the physical and computer sciences and engineering) were…

  6. Development and application of PET-MRI image fusion technology

    International Nuclear Information System (INIS)

    Song Jianhua; Zhao Jinhua; Qiao Wenli

    2011-01-01

    The emerging and growing in popularity of PET-CT scanner brings us the convenience and cognizes the advantages such as diagnosis, staging, curative effect evaluation and prognosis for malignant tumor. And the PET-MRI installing maybe a new upsurge when the machine gradually mature, because of the MRI examination without the radiation exposure and with the higher soft tissue resolution. This paper summarized the developing course of image fusion technology and some researches of clinical application about PET-MRI at present, in order to help people to understand the functions and know its wide application of the upcoming new instrument, mainly focuses the application on the central nervous system and some soft tissue lesions. And before PET-MRI popularization, people can still carry out some researches of various image fusion and clinical application on the current equipment. (authors)

  7. Diffusion, confusion and functional MRI

    International Nuclear Information System (INIS)

    Le Bihan, Denis

    2012-01-01

    Diffusion MRI has been introduced in 1985 and has had a very successful life on its own. While it has become a standard for imaging stroke and white matter disorders, the borders between diffusion MRI and the general field of fMRI have always remained fuzzy. First, diffusion MRI has been used to obtain images of brain function, based on the idea that diffusion MRI could also be made sensitive to blood flow, through the intra-voxel incoherent motion (IVIM) concept. Second, the IVIM concept helped better understand the contribution from different vasculature components to the BOLD fMRI signal. Third, it has been shown recently that a genuine fMRI signal can be obtained with diffusion MRI. This 'DfMRI' signal is notably different from the BOLD fMRI signal, especially for its much faster response to brain activation both at onset and offset, which points out to structural changes in the neural tissues, perhaps such as cell swelling, occurring in activated neural tissue. This short article reviews the major steps which have paved the way for this exciting development, underlying how technical progress with MRI equipment has each time been instrumental to expand the horizon of diffusion MRI toward the field of fMRI. (authors)

  8. Utilization of the research reactors for the power reactor control instrumentation development

    International Nuclear Information System (INIS)

    Duchene, J.; Verdant, R.; Gilbert, J.

    1977-01-01

    Studies on characteristics and reliability of control instruments lead to testing with various radiations of various intensities and energy spectra. Osiris and Triton reactors present this great variety of radiations and a flexibility of use better than power reactors [fr

  9. Qualitative to Quantitative and Spectrum to Report: An Instrument-Focused Research Methods Course for First-Year Students

    Science.gov (United States)

    Thomas, Alyssa C.; Boucher, Michelle A.; Pulliam, Curtis R.

    2015-01-01

    Our Introduction to Research Methods course is a first-year majors course built around the idea of helping students learn to work like chemists, write like chemists, and think like chemists. We have developed this course as a hybrid hands-on/ lecture experience built around instrumentation use and report preparation. We take the product from one…

  10. A Reliable and Valid Weighted Scoring Instrument for Use in Grading APA-Style Empirical Research Report

    Science.gov (United States)

    Greenberg, Kathleen Puglisi

    2012-01-01

    The scoring instrument described in this article is based on a deconstruction of the seven sections of an American Psychological Association (APA)-style empirical research report into a set of learning outcomes divided into content-, expression-, and format-related categories. A double-weighting scheme used to score the report yields a final grade…

  11. Translation and Cross-Cultural Adaptation of Assessment Instruments Used in Psychological Research with Children and Families

    Science.gov (United States)

    van Widenfelt, Brigit M.; Treffers, Philip D. A.; de Beurs, Edwin; Siebelink, Bart M.; Koudijs, Els

    2005-01-01

    With the increased globalization of psychology and related fields, having reliable and valid measures that can be used in a number of languages and cultures is critical. Few guidelines or standards have been established in psychology for the translation and cultural adaptation of instruments. Usually little is reported in research publications…

  12. Asynchronous neuro-osseous growth in adolescent idiopathic scoliosis - MRI-based research

    International Nuclear Information System (INIS)

    Chu, Winnie C.W.; Rasalkar, Darshana D.; Cheng, Jack C.Y.

    2011-01-01

    Adolescent idiopathic scoliosis (AIS) is a common worldwide problem and has been treated for many decades; however, there still remain uncertain areas about this disorder. Its involvement and impact on different parts of the human body remain underestimated due to lack of technology in imaging for objective assessment in the past. The advances in imaging technique and image analysis technology have provided a novel approach for the understanding of the phenotypic presentation of neuro-osseous changes in AIS patients as compared with normal controls. This review is the summary of morphological assessment of the skeletal and nervous systems in girls with AIS based on MRI. Girls with AIS are found to have morphological differences in multiple areas including the vertebral column, spinal cord, skull and brain when compared with age- and sex-matched normal controls. Taken together, the abnormalities in the skeletal system and nervous system of AIS are likely to be inter-related and reflect a systemic process of asynchronous neuro-osseous growth. The current knowledge about the anatomical changes in AIS has important implications with respect to the understanding of fundamental pathomechanical processes involved in the evolution of the scoliotic deformity. (orig.)

  13. Asynchronous neuro-osseous growth in adolescent idiopathic scoliosis - MRI-based research

    Energy Technology Data Exchange (ETDEWEB)

    Chu, Winnie C.W.; Rasalkar, Darshana D. [The Chinese University of Hong Kong, Department of Diagnostic Radiology and Organ Imaging, Hong Kong, SAR (China); Cheng, Jack C.Y. [The Chinese University of Hong Kong, Department of Orthopaedics and Traumatology, Hong Kong, SAR (China)

    2011-09-15

    Adolescent idiopathic scoliosis (AIS) is a common worldwide problem and has been treated for many decades; however, there still remain uncertain areas about this disorder. Its involvement and impact on different parts of the human body remain underestimated due to lack of technology in imaging for objective assessment in the past. The advances in imaging technique and image analysis technology have provided a novel approach for the understanding of the phenotypic presentation of neuro-osseous changes in AIS patients as compared with normal controls. This review is the summary of morphological assessment of the skeletal and nervous systems in girls with AIS based on MRI. Girls with AIS are found to have morphological differences in multiple areas including the vertebral column, spinal cord, skull and brain when compared with age- and sex-matched normal controls. Taken together, the abnormalities in the skeletal system and nervous system of AIS are likely to be inter-related and reflect a systemic process of asynchronous neuro-osseous growth. The current knowledge about the anatomical changes in AIS has important implications with respect to the understanding of fundamental pathomechanical processes involved in the evolution of the scoliotic deformity. (orig.)

  14. Life extension activities and modernization strategies for instrumentation ampersand control systems of research and power reactors in India

    International Nuclear Information System (INIS)

    Chaganty, S.P.; Bairi, B.R.

    1993-01-01

    Based on three and half decades of experience gained in the operation and maintenance of Instrumentation and Control Systems of nuclear reactors in India, specific investigations were made to understand various aspects of aging. The analysis of the failure rates of various instruments, plant outage figures and obsolescence of components have necessitated the replacement of instrumentation to improve the reliability and performance. The aging models available were used to determine the extent of performance degradation and to formulate maintenance strategies. The nuclear instrumentation of the aging research reactors at Bhabha Atomic Research Centre (BARC) has been replaced with high reliability equipment using modern integrated circuits. This has resulted in an improvement in the mean time between failure (MTBF) by a factor of five. The neutronic instrumentation of Fast Breeder Test Reactor (FBTR) at Madras is currently being upgraded with the introduction of microprocessor based safety units for reactivity computation and online testing of safety logic with Fine Impulse Technique. The operating experience has also indicated the necessity of developing online surveillance methods and status monitoring of various systems to detect aging. Online cable insulation measurement technique and noise analysis methods for vibration monitoring have been developed. Campbell method of signal processing has been successfully used in extending the useful life of Local Power Range monitors in the Boiling Water Reactor at Tarapur. In order to improve reliability, accuracy and provide efficient man machine interface, microprocessor based systems with online testing features have been installed in power reactors. These include the high performance reactor regulating system and centralised radiation monitoring systems commissioned at Kakrapara power station. The paper describes the above systems and the modernization strategies for nuclear instrumentation and control

  15. Bridging the Educational Research-Teaching Practice Gap: Tools for Evaluating the Quality of Assessment Instruments

    Science.gov (United States)

    Anderson, Trevor R.; Rogan, John M.

    2010-01-01

    Student assessment is central to the educational process and can be used for multiple purposes including, to promote student learning, to grade student performance and to evaluate the educational quality of qualifications. It is, therefore, of utmost importance that assessment instruments are of a high quality. In this article, we present various…

  16. Nuclear medicine and imaging research (instrumentation and quantitative methods of evaluation)

    International Nuclear Information System (INIS)

    Beck, R.N.; Cooper, M.; Chen, C.T.

    1992-07-01

    This document is the annual progress report for project entitled ''Instrumentation and Quantitative Methods of Evaluation.'' Progress is reported in separate sections individually abstracted and indexed for the database. Subject areas reported include theoretical studies of imaging systems and methods, hardware developments, quantitative methods of evaluation, and knowledge transfer: education in quantitative nuclear medicine imaging

  17. Research on conceptual design of simplified nuclear safety instrument and control system

    International Nuclear Information System (INIS)

    Huang Jie

    2015-01-01

    The Nuclear safety instrument and control system is directly related to the safety of the reactor. So redundant and diversity design is used to ensure the system's security and reliability. This make the traditional safety system large, more cabinets and wiring complexity. To solve these problem, we can adopt new technology to make the design more simple. The simplify conceptual design can make the system less cabinets, less wiring, but high security, strong reliability. (author)

  18. Content validity--establishing and reporting the evidence in newly developed patient-reported outcomes (PRO) instruments for medical product evaluation: ISPOR PRO good research practices task force report: part 1--eliciting concepts for a new PRO instrument.

    Science.gov (United States)

    Patrick, Donald L; Burke, Laurie B; Gwaltney, Chad J; Leidy, Nancy Kline; Martin, Mona L; Molsen, Elizabeth; Ring, Lena

    2011-12-01

    The importance of content validity in developing patient reported outcomes (PRO) instruments is stressed by both the US Food and Drug Administration and the European Medicines Agency. Content validity is the extent to which an instrument measures the important aspects of concepts that developers or users purport it to assess. A PRO instrument measures the concepts most significant and relevant to a patient's condition and its treatment. For PRO instruments, items and domains as reflected in the scores of an instrument should be important to the target population and comprehensive with respect to patient concerns. Documentation of target population input in item generation, as well as evaluation of patient understanding through cognitive interviewing, can provide the evidence for content validity. Developing content for, and assessing respondent understanding of, newly developed PRO instruments for medical product evaluation will be discussed in this two-part ISPOR PRO Good Research Practices Task Force Report. Topics include the methods for generating items, documenting item development, coding of qualitative data from item generation, cognitive interviewing, and tracking item development through the various stages of research and preparing this tracking for submission to regulatory agencies. Part 1 covers elicitation of key concepts using qualitative focus groups and/or interviews to inform content and structure of a new PRO instrument. Part 2 covers the instrument development process, the assessment of patient understanding of the draft instrument using cognitive interviews and steps for instrument revision. The two parts are meant to be read together. They are intended to offer suggestions for good practices in planning, executing, and documenting qualitative studies that are used to support the content validity of PRO instruments to be used in medical product evaluation. Copyright © 2011 International Society for Pharmacoeconomics and Outcomes Research (ISPOR

  19. Quality assurance in functional MRI

    DEFF Research Database (Denmark)

    Liu, Thomas T; Glover, Gary H; Mueller, Bryon A

    2015-01-01

    Over the past 20 years, functional magnetic resonance imaging (fMRI) has ben- efited greatly from improvements in MRI hardware and software. At the same time, fMRI researchers have pushed the technical limits of MRI systems and greatly in- fluenced the development of state-of-the-art systems...... consistent data throughout the course of a study, and consistent stability across time and sites is needed to allow data from different time periods or acquisition sites to be optimally integrated....

  20. Conditioned Stimuli’s Role in Relapse: Pre-Clinical Research on Pavlovian Instrumental Transfer

    Science.gov (United States)

    Lamb, R.J.; Schindler, W.; Pinkston, Jonathan W.

    2016-01-01

    Rationale and Objective Pavlovian learning is central to many theories of addiction. In these theories, stimuli paired with drug ingestion become Conditioned Stimuli (CS) and subsequently elicit drug-seeking and -taking. However in most relevant studies, Pavlovian and instrumental learning are confounded. This confound may be avoided in Pavlovian-Instrumental-Transfer (PIT) procedures. In PIT, Pavlovian and instrumental learning are established separately, and then combined. In order to better understand the role of CSs in addiction, we review the relevant studies using PIT. Findings We identified seven articles examining PIT effects of ethanol- or cocaine-paired CSs. Under at least one condition six of these articles reported CS-elicited increases in responding previously maintained by drug. However, the only study using the optimal control condition failed to find a CS-elicited increase. Two studies examining CS specificity found the CS also increased responding maintained by a different reinforcer. Two studies examined if CSs elicit increases in actual drug-taking. Both failed to find CS-elicited increases, i.e., no study shows CS-elicited increases in actual drug-taking. Further, CS-elicited increases in extinguished responding are short-lived. Conclusions These findings are not entirely consistent with Pavlovian learning playing a central role in addiction. However, design issues can explain most of these inconsistencies. Studies without these design issues are needed. Additionally, existing theories hypothesize drug-paired CSs increase drug-taking by increasing motivation, by eliciting conditioned responses that make drug-seeking more probable, or by a combination of these. Work distinguishing between these mechanisms would also be useful. PMID:26800688

  1. Chest MRI

    Science.gov (United States)

    ... resonance imaging - chest; NMR - chest; MRI of the thorax; Thoracic MRI Patient Instructions ... Gotway MB, Panse PM, Gruden JF, Elicker BM. Thoracic radiology. In: Broaddus VC, Mason RJ, Ernst JD, et ...

  2. Roadmap for Research, Development, and Demonstration of Instrumentation, Controls, and Human-Machine Interface Technologies

    International Nuclear Information System (INIS)

    Miller, Don W.; Arndt, Steven A.; Bond, Leonard J.; Dudenhoeffer, Donald D.; Hallbert, Bruce P.; Holcomb, David E.; Wood, Richard T.; Naser, Joseph A.; O'Hara, John M.; Quinn, Edward L.

    2008-01-01

    Instrumentation, controls, and human-machine interfaces are essential enabling technologies that strongly influence nuclear power plant performance and operational costs. The nuclear power industry is currently engaged in a transition from traditional analog-based instrumentation, controls, and human-machine interface (ICHMI) systems to implementations employing digital technologies. This transition has primarily occurred in an ad hoc fashion through individual system upgrades at existing plants and has been constrained by a number of concerns. Although international implementation of evolutionary nuclear power plants and the progression toward new plants in the United States have spurred design of more fully digital plant-wide ICHMI systems, the experience base in the nuclear power application domain is limited. Additionally, design and development programs by the U.S. Department of Energy (DOE) for advanced reactor concepts, such as the Generation IV Program and Next Generation Nuclear Plant (NGNP), introduce different plant conditions and unique plant configurations that increase the need for enhanced ICHMI capabilities to fully achieve programmatic goals related to economic competitiveness, safety and reliability, sustainability, and proliferation resistance and physical protection. As a result, there are challenges that need to be addressed to enable the nuclear power industry to effectively and efficiently complete the transition to safe and comprehensive use of digital technology

  3. Cyber security level assignment for research reactor digital instrumentation and control system architecture using concept of defense in depth

    International Nuclear Information System (INIS)

    Shin, Jin Soo; Heo, Gyun Young; Son, Han Seong; Kim, Young Ki; Park, Jaek Wan

    2012-01-01

    Due to recent aging of the analog instrumentation of many nuclear power plants (NPPs) and research reactors, the system reliability decreases while maintenance and testing costs increase. In addition, it is difficult to find the substitutable analog equipment s due to obsolescence. Therefore, the instrumentation and control (I and C) systems have changed from analog system to digital system due to these facts. With the introduction of digital systems, research reactors are forced to care for the problem of cyber attacks because I and C systems have been digitalized using networks or communication systems. Especially, it is more issued at research reactors due to the accessibility of human resources. In the real world, an IBM researcher has been successful in controlling the software by penetrating a NPPs network in U.S. on July 2008 and acquiring the control right of nuclear facilities after one week. Moreover, the malignant code called 'stuxnet' impaired the nearly 1,000 centrifugal separators in Iran according to an IAEA report. The problem of cyber attacks highlights the important of cyber security, which should be emphasized. Defense.in.depth (DID) is a significant concept for the cyber security to work properly. DID institutes and maintains a hardy program for critical digital asset (CDA) by implementing multiple security boundaries. In this work, we assign cyber security levels to a typical digital I and C system using DID concept. This work is very useful in applying the concept of DID to nuclear industry with respect to cyber security

  4. Cyber security level assignment for research reactor digital instrumentation and control system architecture using concept of defense in depth

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Jin Soo; Heo, Gyun Young [Kyung Hee University, Seoul (Korea, Republic of); Son, Han Seong [Joongbu Univ., Chungnam (Korea, Republic of); Kim, Young Ki; Park, Jaek Wan [KAERI, Daejeon (Korea, Republic of)

    2012-10-15

    Due to recent aging of the analog instrumentation of many nuclear power plants (NPPs) and research reactors, the system reliability decreases while maintenance and testing costs increase. In addition, it is difficult to find the substitutable analog equipment s due to obsolescence. Therefore, the instrumentation and control (I and C) systems have changed from analog system to digital system due to these facts. With the introduction of digital systems, research reactors are forced to care for the problem of cyber attacks because I and C systems have been digitalized using networks or communication systems. Especially, it is more issued at research reactors due to the accessibility of human resources. In the real world, an IBM researcher has been successful in controlling the software by penetrating a NPPs network in U.S. on July 2008 and acquiring the control right of nuclear facilities after one week. Moreover, the malignant code called 'stuxnet' impaired the nearly 1,000 centrifugal separators in Iran according to an IAEA report. The problem of cyber attacks highlights the important of cyber security, which should be emphasized. Defense.in.depth (DID) is a significant concept for the cyber security to work properly. DID institutes and maintains a hardy program for critical digital asset (CDA) by implementing multiple security boundaries. In this work, we assign cyber security levels to a typical digital I and C system using DID concept. This work is very useful in applying the concept of DID to nuclear industry with respect to cyber security.

  5. The Goldstone solar system radar: A science instrument for planetary research

    Science.gov (United States)

    Dvorsky, J. D.; Renzetti, N. A.; Fulton, D. E.

    1992-01-01

    The Goldstone Solar System Radar (GSSR) station at NASA's Deep Space Communications Complex in California's Mojave Desert is described. A short chronological account of the GSSR's technical development and scientific discoveries is given. This is followed by a basic discussion of how information is derived from the radar echo and how the raw information can be used to increase understanding of the solar system. A moderately detailed description of the radar system is given, and the engineering performance of the radar is discussed. The operating characteristics of the Arcibo Observatory in Puerto Rico are briefly described and compared with those of the GSSR. Planned and in-process improvements to the existing radar, as well as the performance of a hypothetical 128-m diameter antenna radar station, are described. A comprehensive bibliography of referred scientific and engineering articles presenting results that depended on data gathered by the instrument is provided.

  6. [Research on fractal tones generating method for tinnitus rehabilitation based on musical instrument digital interface technology].

    Science.gov (United States)

    Wang, Lu; He, Peiyu; Pan, Fan

    2014-08-01

    Tinnitus is a subjective sensation of sound without external stimulation. It has become ubiquitous and has therefore aroused much attention in recent years. According to the survey, ameliorating tinnitus based on special music and reducing pressure have good effects on the treatment of it. Meantime, vicious cycle chains between tinnitus and bad feelings have been broken. However, tinnitus therapy has been restricted by using looping music. Therefore, a method of generating fractal tones based on musical instrument digital interface (MIDI) technology and pink noise has been proposed in this paper. The experimental results showed that the fractal fragments were self-similar, incompletely reduplicate, and no sudden changes in pitches and would have a referential significance for tinnitus therapy.

  7. Gadolinium for neutron detection in current nuclear instrumentation research: A review

    Science.gov (United States)

    Dumazert, J.; Coulon, R.; Lecomte, Q.; Bertrand, G. H. V.; Hamel, M.

    2018-02-01

    Natural gadolinium displays a number of remarkable physical properties: it is a rare earth element, composed of seven stable or quasi-stable isotopes, with an exceptionally high magnetization and a Curie point near room temperature. Its use in the field of nuclear instrumentation historically relates to its efficiency as a neutron poison in power reactors. Gadolinium is indeed the naturally occurring element with the highest interaction probability with neutrons at thermal energy, shared between Gd-157 (15.65%, 254000 b cross section) and Gd-155 (14.8%, 60900 b) isotopes. Considering that neutron capture results in an isotopic change, followed by a radiative rearrangement of nuclear and atomic structures, Gd may be embodied not merely as a neutron poison but as a neutron converter into a prompt photon and an electron source term. Depending on the nature and energy of the reaction products (from a few-keV Auger electrons up to 8 MeV gamma rays) that the detector aims at isolating as an indirect neutron signature, a variety of sensor media and counting methods have been introduced during the last decades. This review first draws a theoretical description of the radiative cascade following Gd(n , γ) capture. The cascade may be subdivided into regions of interest, each corresponding to dedicated detection designs and optimizations whose current status is detailed. This inventory has allowed the authors to extract and benchmark key figures of merit for the definition of a detection scheme: neutron attenuation, neutron sensitivity (cps/nv), gamma rejection, neutron detection limit in a mixed field, intrinsic or extrinsic moderation, and transportability. On this basis, the authors have identified promising paths for Gd-based neutron detection in contemporary instrumentation.

  8. Reactor materials research as an effective instrument of nuclear reactor perfection

    International Nuclear Information System (INIS)

    Baryshnikov, M.

    2006-01-01

    The work is devoted to reactor materiology, as to the practical tool of nuclear reactor development. The work is illustrated with concrete examples from activity experience of the appropriate division of the Russian Research Centre Kurchatov Institute - Institute of Reactor Materials Research and Radiation Nanotechnologies. Besides the description of some modern potentials of the mentioned institute is given. (author)

  9. Application of fMRI to obesity research: differences in reward pathway activation measured with fMRI BOLD during visual presentation of high and low calorie foods

    Science.gov (United States)

    Tsao, Sinchai; Adam, Tanja C.; Goran, Michael I.; Singh, Manbir

    2012-03-01

    The factors behind the neural mechanisms that motivate food choice and obesity are not well known. Furthermore, it is not known when these neural mechanisms develop and how they are influenced by both genetic and environmental factors. This study uses fMRI together with clinical data to shed light on the aforementioned questions by investigating how appetite-related activation in the brain changes with low versus high caloric foods in pre-pubescent girls. Previous studies have shown that obese adults have less striatal D2 receptors and thus reduced Dopamine (DA) signaling leading to the reward-deficit theory of obesity. However, overeating in itself reduces D2 receptor density, D2 sensitivity and thus reward sensitivity. The results of this study will show how early these neural mechanisms develop and what effect the drastic endocrinological changes during puberty has on these mechanisms. Our preliminary results showed increased activations in the Putamen, Insula, Thalamus and Hippocampus when looking at activations where High Calorie > Low Calorie. When comparing High Calorie > Control and Low Calorie > Control, the High > Control test showed increased significant activation in the frontal lobe. The Low > Control also yielded significant activation in the Left and Right Fusiform Gyrus, which did not appear in the High > Control test. These results indicate that the reward pathway activations previously shown in post-puberty and adults are present in pre-pubescent teens. These results may suggest that some of the preferential neural mechanisms of reward are already present pre-puberty.

  10. Las Ciencias instrumentales en la Investigación Biomédica Instrumental Sciences in Biomedical Research

    Directory of Open Access Journals (Sweden)

    Josep Roma Millán

    2004-03-01

    Full Text Available Hay una serie de ciencias que se hacen imprescindibles para poder investigar e interpretar los resultados científicos, son la ciencias que llamamos instrumentales o auxiliares. Entre ellas se encuentran la Demografía, la Epidemiología y la Bioestadística. Además, hay que tomar en consideración las técnicas de investigación cualitativa, el conjunto de estrategias e instrumentos de búsqueda de información bibliográfica y, también las metodologías de presentación de resultados. Finalmente, no puede olvidarse la ética, en sus dos componentes de bioética y de ética del trabajo científico, si queremos desarrollar un trabajo siguiendo el método científico. Este capítulo explica cuál es la función de estas disciplinas en el seno de la investigación científica y del desarrollo de proyectos.Some scientific disciplines are essential for research and scientific results interpretation. Instrumental or auxiliary sciences include Demography, Epidemiology, and Biostatistics. Also, it is necessary to take into account the techniques for qualitative research, the strategies and instruments for bibliographic information and the methodology for scientific results presentation. Finally, to develop a project according to the scientific method, it is necessary to consider ethics, in its two components: bioethics and the ethics of scientific method. This report explains which is the function of these instrumental and auxiliary sciences in the context of the scientific research and the development of scientific projects.

  11. Geospace ionosphere research with a MF/HF radio instrument on a cubesat

    Science.gov (United States)

    Kallio, E. J.; Aikio, A. T.; Alho, M.; Fontell, M.; van Gijlswijk, R.; Kauristie, K.; Kestilä, A.; Koskimaa, P.; Makela, J. S.; Mäkelä, M.; Turunen, E.; Vanhamäki, H.

    2016-12-01

    Modern technology provides new possibilities to study geospace and its ionosphere, using spacecraft and and computer simulations. A type of nanosatellites, CubeSats, provide a cost effective possibility to provide in-situ measurements in the ionosphere. Moreover, combined CubeSat observations with ground-based observations gives a new view on auroras and associated electromagnetic phenomena. Especially joint and active CubeSat - ground based observation campaigns enable the possibility of studying the 3D structure of the ionosphere. Furthermore using several CubeSats to form satellite constellations enables much higher temporal resolution. At the same time, increasing computation capacity has made it possible to perform simulations where properties of the ionosphere, such as propagation of the electromagnetic waves in the medium frequency, MF (0.3-3 MHz) and high frequency, HF (3-30 MHz), ranges is based on a 3D ionospheric model and on first-principles modelling. Electromagnetic waves at those frequencies are strongly affected by ionospheric electrons and, consequently, those frequencies can be used for studying the plasma. On the other hand, even if the ionosphere originally enables long-range telecommunication at MF and HF frequencies, the frequent occurrence of spatiotemporal variations in the ionosphere disturbs communication channels, especially at high latitudes. Therefore, study of the MF and HF waves in the ionosphere has both a strong science and technology interests. We present computational simulation results and measuring principles and techniques to investigate the arctic ionosphere by a polar orbiting CubeSat whose novel AM radio instrument measures HF and MF waves. The cubesat, which contains also a white light aurora camera, is planned to be launched in 2017 (http://www.suomi100satelliitti.fi/eng). We have modelled the propagation of the radio waves, both ground generated man-made waves and space formed space weather related waves, through the 3D

  12. Safety evaluation for instrumentation and control system upgrading project of Malaysian TRIGA MARK II PUSPATI Research reactor

    International Nuclear Information System (INIS)

    Ridha Roslan; Nik Mohd Faiz Khairuddin

    2013-01-01

    Full-text: Malaysian TRIGA MARK II research reactor has been in safe operation since its first criticality in 1982. The reactor is licensed to be operated by Malaysian Nuclear Agency to perform training and research development related activities. Due to its extensive operation since last three decades, the option of modifications for safety and safety-related item and component become a necessary to replace the outdated equipment to a stat-of-art, reliable technologies. This paper will present the current regulatory activities performed by Atomic Energy Licensing Board (AELB) to ensure the upgrading of analogue to digital instrumentation and control system is implemented in safe manner. The review activity includes documentation review, manufacturer quality audit and on-site inspection for commissioning. The review performed by AELB is based on The International Atomic Energy Agency (IAEA) Safety Requirements NS-R-4, entitled Safety of Research Reactors. During this endeavour, AELB seeks technical cooperation from Korea Institute of Nuclear Safety (KINS), the nuclear experts organization of the country of origin of the instrumentation and control technology. The regulatory activity is still on-going and is expected to be completed by issuance of Authorization for Restart on December 2013. (author)

  13. Measuring social science concepts in pharmacy education research: From definition to item analysis of self-report instruments.

    Science.gov (United States)

    Cor, M Ken

    Interpreting results from quantitative research can be difficult when measures of concepts are constructed poorly, something that can limit measurement validity. Social science steps for defining concepts, guidelines for limiting construct-irrelevant variance when writing self-report questions, and techniques for conducting basic item analysis are reviewed to inform the design of instruments to measure social science concepts in pharmacy education research. Based on a review of the literature, four main recommendations emerge: These include: (1) employ a systematic process of conceptualization to derive nominal definitions; (2) write exact and detailed operational definitions for each concept, (3) when creating self-report questionnaires, write statements and select scales to avoid introducing construct-irrelevant variance (CIV); and (4) use basic item analysis results to inform instrument revision. Employing recommendations that emerge from this review will strengthen arguments to support measurement validity which in turn will support the defensibility of study finding interpretations. An example from pharmacy education research is used to contextualize the concepts introduced. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Outcome in adolescent idiopathic scoliosis after brace treatment and surgery assessed by means of the Scoliosis Research Society Instrument 24

    OpenAIRE

    Weigert, Karen Petra; Nygaard, Linda Marie; Christensen, Finn Bjarke; Hansen, Ebbe Stender; Bünger, Cody

    2005-01-01

    A retrospectively designed long-term follow-up study of adolescent idiopathic scoliosis (AIS) patients who had completed treatment, of at least 2 years, by means of brace, surgery, or both brace and surgery. This study is to assess the outcome after treatment for AIS by means of the Scoliosis Research Society Outcome Instrument 24 (SRS 24). One hundred and eighteen AIS patients (99 females and 19 males), treated at the Aarhus University Hospital from January 1, 1987 to December 31, 1997, were...

  15. The impact of twenty years of noise research on nuclear power plant design, instrumentation and control

    International Nuclear Information System (INIS)

    Kemeny, L.G.

    1975-01-01

    Early investigations demonstrated that time constants and the dynamic characteristics of low energy nuclear systems could be elegantly determined by correlation of spectral analysis of fluctuating signals from ion chambers and proportional counters. Analyses of the time series information and the multi-filtering operations in the frequency domain were time consuming and tedious projects due to the lack of suitable data processing equipment. During the last decade, the significant advances were the recognition of the advantages of the two-channel cross-correlation technique and the realisation that the dynamic behaviour of nuclear power plant at power could be monitored and studied in depth by the cross-correlation of mechanical, thermal and hydrodynamic signals with neutronic information. The former concept led to the development of theoretical models for spatial and energy-dependent noise fields within a nuclear system. The latter opened a floodgate of potential advances in nuclear power plant design optimization, control and safety instrumentation, and control and safety diagnostic systems. (U.K.)

  16. A single-chip event sequencer and related microcontroller instrumentation for atomic physics research.

    Science.gov (United States)

    Eyler, E E

    2011-01-01

    A 16-bit digital event sequencer with 50 ns resolution and 50 ns trigger jitter is implemented by using an internal 32-bit timer on a dsPIC30F4013 microcontroller, controlled by an easily modified program written in standard C. It can accommodate hundreds of output events, and adjacent events can be spaced as closely as 1.5 μs. The microcontroller has robust 5 V inputs and outputs, allowing a direct interface to common laboratory equipment and other electronics. A USB computer interface and a pair of analog ramp outputs can be added with just two additional chips. An optional display/keypad unit allows direct interaction with the sequencer without requiring an external computer. Minor additions also allow simple realizations of other complex instruments, including a precision high-voltage ramp generator for driving spectrum analyzers or piezoelectric positioners, and a low-cost proportional integral differential controller and lock-in amplifier for laser frequency stabilization with about 100 kHz bandwidth.

  17. Instrumentation and control activities at the Electric Power Research Institute to support operator support systems

    International Nuclear Information System (INIS)

    Naser, J.

    1995-01-01

    Most nuclear power plants in the United States continue to operate with analog instrumentation and control (I and C) technology designed 20 to 40 years ago. This equipment is approaching or exceeding its life expectancy, resulting in increasing maintenance efforts to sustain system performance. Decreasing availability of replacement parts and the accelerating deterioration of the infrastructure of manufacturers that support analog technology exacerbate obsolescence problems and resultant operation and maintenance (O and M) cost increases. Modern digital technology holds a significant potential to improve the safety, cost-effectiveness, productivity, and, therefore, competitiveness of nuclear power plants. Operator support systems provide the tools to help achieve this potential. Reliable, integrated information is a critical element for protecting the utility's capital investment and increasing availability, reliability, and productivity. Integrated operator support systems with integrated information can perform more effectively to increase productivity, to enhance safety, and to reduce O and M costs. The plant communications and computing architecture is the infrastructure needed to allow the implementation of I and C systems and associated operator support systems in an integrated manner. Current technology for distributed digital systems, plant process computers, and plant communications and computing networks support the integration of systems and information. (author). 16 refs

  18. The development and validation of an instrument to measure the quality of health research reports in the lay media.

    Science.gov (United States)

    Zeraatkar, Dena; Obeda, Michael; Ginsberg, Jeffrey S; Hirsh, Jack

    2017-04-20

    The media serves as an important link between medical research, as reported in scholarly sources, and the public and has the potential to act as a powerful tool to improve public health. However, concerns about the reliability of health research reports have been raised. Tools to monitor the quality of health research reporting in the media are needed to identify areas of weakness in health research reporting and to subsequently work towards the efficient use of the lay media as a public health tool through which the public's health behaviors can be improved. We developed the Quality Index for health-related Media Reports (QIMR) as a tool to monitor the quality of health research reports in the lay media. The tool was developed according to themes generated from interviews with health journalists and researchers. Item and domain characteristics and scale reliability were assessed. The scale was correlated with a global quality assessment score and media report word count to provide evidence towards its construct validity. The items and domains of the QIMR demonstrated acceptable validity and reliability. Items from the 'validity' domain were negatively skewed, suggesting possible floor effect. These items were not eliminated due to acceptable content and face validity. QIMR total scores produced a strong correlation with raters' global assessment and a moderate correlation with media report word count, providing evidence towards the construct validity of the instrument. The results of this investigation indicate that QIMR can adequately measure the quality of health research reports, with acceptable reliability and validity.

  19. Use of existing patient-reported outcome (PRO) instruments and their modification: the ISPOR Good Research Practices for Evaluating and Documenting Content Validity for the Use of Existing Instruments and Their Modification PRO Task Force Report.

    Science.gov (United States)

    Rothman, Margaret; Burke, Laurie; Erickson, Pennifer; Leidy, Nancy Kline; Patrick, Donald L; Petrie, Charles D

    2009-01-01

    Patient-reported outcome (PRO) instruments are used to evaluate the effect of medical products on how patients feel or function. This article presents the results of an ISPOR task force convened to address good clinical research practices for the use of existing or modified PRO instruments to support medical product labeling claims. The focus of the article is on content validity, with specific reference to existing or modified PRO instruments, because of the importance of content validity in selecting or modifying an existing PRO instrument and the lack of consensus in the research community regarding best practices for establishing and documenting this measurement property. Topics addressed in the article include: definition and general description of content validity; PRO concept identification as the important first step in establishing content validity; instrument identification and the initial review process; key issues in qualitative methodology; and potential threats to content validity, with three case examples used to illustrate types of threats and how they might be resolved. A table of steps used to identify and evaluate an existing PRO instrument is provided, and figures are used to illustrate the meaning of content validity in relationship to instrument development and evaluation. RESULTS & RECOMMENDATIONS: Four important threats to content validity are identified: unclear conceptual match between the PRO instrument and the intended claim, lack of direct patient input into PRO item content from the target population in which the claim is desired, no evidence that the most relevant and important item content is contained in the instrument, and lack of documentation to support modifications to the PRO instrument. In some cases, careful review of the threats to content validity in a specific application may be reduced through additional well documented qualitative studies that specifically address the issue of concern. Published evidence of the content

  20. Openly Published Environmental Sensing (OPEnS) | Advancing Open-Source Research, Instrumentation, and Dissemination

    Science.gov (United States)

    Udell, C.; Selker, J. S.

    2017-12-01

    The increasing availability and functionality of Open-Source software and hardware along with 3D printing, low-cost electronics, and proliferation of open-access resources for learning rapid prototyping are contributing to fundamental transformations and new technologies in environmental sensing. These tools invite reevaluation of time-tested methodologies and devices toward more efficient, reusable, and inexpensive alternatives. Building upon Open-Source design facilitates community engagement and invites a Do-It-Together (DIT) collaborative framework for research where solutions to complex problems may be crowd-sourced. However, barriers persist that prevent researchers from taking advantage of the capabilities afforded by open-source software, hardware, and rapid prototyping. Some of these include: requisite technical skillsets, knowledge of equipment capabilities, identifying inexpensive sources for materials, money, space, and time. A university MAKER space staffed by engineering students to assist researchers is one proposed solution to overcome many of these obstacles. This presentation investigates the unique capabilities the USDA-funded Openly Published Environmental Sensing (OPEnS) Lab affords researchers, within Oregon State and internationally, and the unique functions these types of initiatives support at the intersection of MAKER spaces, Open-Source academic research, and open-access dissemination.

  1. Magnetic Resonance Medical Imaging (MRI)-from the inside

    Science.gov (United States)

    Bottomley, Paul

    There are about 36,000 magnetic resonance imaging (MRI) scanners in the world, with annual sales of 2500. In the USA about 34 million MRI studies are done annually, and 60-70% of all scanners operate at 1.5 Tesla (T). In 1982 there were none. How MRI got to be-and how it got to1.5T is the subject of this talk. Its an insider's view-mine-as a physics PhD student at Nottingham University when MRI (almost) began, through to the invention of the 1.5T clinical MRI scanner at GE's research center in Schenectady NY.Before 1977 all MRI was done on laboratory nuclear magnetic resonance instruments used for analyzing small specimens via chemical shift spectroscopy (MRS). It began with Lauterbur's 1973 observation that turning up the spectrometer's linear gradient magnetic field, generated a spectrum that was a 1D projection of the sample in the direction of the gradient. What followed in the 70's was the development of 3 key methods of 3D spatial localization that remain fundamental to MRI today.As the 1980's began, the once unimaginable prospect of upscaling from 2cm test-tubes to human body-sized magnets, gradient and RF transmit/receive systems, was well underway, evolving from arm-sized, to whole-body electromagnet-based systems operating at plan was to drop the field to 0.3T. We opted to make MRI work at 1.5T instead. The result was a scanner that could study both anatomy and metabolism with a SNR way beyond its lower field rivals. MRI's success truly reflects the team efforts of many: from the NMR physics to the engineering of magnets, gradient and RF systems.

  2. Research on the improvement of traditional dial instrument precision based on C8051F020.

    Science.gov (United States)

    Sun, Guiling; Liu, Yi; Lu, Li

    2006-11-01

    Two essential parameters to weigh the quality of a reinforcing steel bar are the value of its bending force and the maximum pull it can withstand, in order to measure them with higher precision, it is significant to describe the changing tendency of force with time and displacement by drawing a real-time curve directly during the process examining the quality of a bar when the pull exerted is variable continuously. Using C8051F020 as the core component, this paper improves traditional dial instruments whose precision can only reach the second level. Adopting a high precision pulling/pressing force sensor, an amplifier, a two-order Butterworth low-pass filter and a 12-bit AD converter which is in the C8051F020, the first level of precision can be obtained. A rotary encoder is used to measure the length increment of the bar during the pulling process, based on an algorithm, a force-displacement (or time) curve which is quite important for operators to control the course of experiment can be displayed on the LCD. Meanwhile, real-time experimental data can be stored in local flash, or uploaded to PC by RS-485 and stored in the center database. A real-time clock is also adopted to mark the time of each experiment that is useful to index the data. The measure system we describe here is characterized by simple structure, high precision and stabilization, and convenience operation, can be used in other actual measure systems by only changing the front sensor, so it is of great value of application and popularization.

  3. Research pressure instrumentation for NASA Space Shuttle main engine, modification no. 6

    Science.gov (United States)

    Anderson, P. J.; Johnson, R. L.

    1984-01-01

    Research concerning the utilization of silicon piezoresistive strain sensing technology for space shuttle main engine applications is reported. The following specific topics were addressed: (1) transducer design and materials, (2) silicon piezoresistor characterization at cryogenic temperatures, (3) chip mounting characterization, and (4) frequency response optimization.

  4. Proceedings of the advanced research and technology development direct utilization, instrumentation and diagnostics contractors' review meeting

    Energy Technology Data Exchange (ETDEWEB)

    Geiling, D.W. (USDOE Morgantown Energy Technology Center, WV (USA)); Goldberg, P.M. (eds.) (USDOE Pittsburgh Energy Technology Center, PA (USA))

    1990-01-01

    The 1990 Advanced Research and Technology Development (AR TD) Direct Utilization, and Instrumentation and Diagnostics Contractors Review Meeting was held September 16--18, 1990, at the Hyatt at Chatham Center in Pittsburgh, PA. The meeting was sponsored by the US Department of Energy (DOE), Office of Fossil Energy, and the Pittsburgh and Morgantown Energy Technology Centers. Each year the meeting provides a forum for the exchange of information among the DOE AR TD contractors and interested parties. This year's meeting was hosted by the Pittsburgh Energy Technology Center and was attended by 120 individuals from industry, academia, national laboratories, and other governmental agencies. Papers were presented on research addressing coal surface, science, devolatilization and combustion, ash behavior, emission controls for gases particulates, fluid bed combustion and utilization in diesels and turbines. Individual reports are processed separately for the data bases.

  5. Design and development of fast pneumatic transfer system (PTS) for instrumental neutron activation analysis at Jordan research reactor

    International Nuclear Information System (INIS)

    Chung, Yongsam; Kim, Sunha; Moon, Jonghwa; Choi, Jinbok; Lee, Jongmin; Ryu, Jungsu

    2013-01-01

    A pneumatic transfer system (PTS) is one of the important equipment used for an neutron irradiation of a target material for an instrumental neutron activation analysis (INAA) in a research reactor. In particular, a rapid pneumatic transportation of irradiation capsule is essential for an accurate measurement of a short half-life nuclide. Three types of PTS for NAA facility at the Jordan Research and Training Reactor (JRTR) were newly developed for a functional improvement involving a manual and an automatic system which is equipped with programmable logic controller, software, and 13 devices to facilitate optimal operation of the system. In this paper, the designs and construction of these PTS, the operation and control of the system are described. In addition, a functional and operational test of the system were carried out as one of the basic requirement and characteristic parameters, and the results were reported to provide a user information as well as for the management and safety of the reactor

  6. IN-PILE INSTRUMENTATION TO SUPPORT FUEL CYCLE RESEARCH AND DEVELOPMENT - FY12 STATUS REPORT

    Energy Technology Data Exchange (ETDEWEB)

    J. . Rempe; J. Daw; D. Knudson; R. Schley

    2012-09-01

    As part of the FCRD program objective to emphasize science-based, goal-oriented research, a strategic research program is underway to develop new sensors that can be used to obtain the high fidelity, real-time, data required for characterizing the performance of new fuels during irradiation testing. The overarching goal of this initiative is to develop new test vehicles with new sensors of unprecedented accuracy and resolution that can obtain the required data. Prior laboratory testing and, as needed, irradiation testing of sensors in these capsules will be completed as part of this initiative to give sufficient confidence that the irradiation tests will yield the required data. This report documents FY12 progress in this initiative.

  7. Montreal Archive of Sleep Studies: an open-access resource for instrument benchmarking and exploratory research.

    Science.gov (United States)

    O'Reilly, Christian; Gosselin, Nadia; Carrier, Julie; Nielsen, Tore

    2014-12-01

    Manual processing of sleep recordings is extremely time-consuming. Efforts to automate this process have shown promising results, but automatic systems are generally evaluated on private databases, not allowing accurate cross-validation with other systems. In lacking a common benchmark, the relative performances of different systems are not compared easily and advances are compromised. To address this fundamental methodological impediment to sleep study, we propose an open-access database of polysomnographic biosignals. To build this database, whole-night recordings from 200 participants [97 males (aged 42.9 ± 19.8 years) and 103 females (aged 38.3 ± 18.9 years); age range: 18-76 years] were pooled from eight different research protocols performed in three different hospital-based sleep laboratories. All recordings feature a sampling frequency of 256 Hz and an electroencephalography (EEG) montage of 4-20 channels plus standard electro-oculography (EOG), electromyography (EMG), electrocardiography (ECG) and respiratory signals. Access to the database can be obtained through the Montreal Archive of Sleep Studies (MASS) website (http://www.ceams-carsm.ca/en/MASS), and requires only affiliation with a research institution and prior approval by the applicant's local ethical review board. Providing the research community with access to this free and open sleep database is expected to facilitate the development and cross-validation of sleep analysis automation systems. It is also expected that such a shared resource will be a catalyst for cross-centre collaborations on difficult topics such as improving inter-rater agreement on sleep stage scoring. © 2014 European Sleep Research Society.

  8. The scientific and technological research as an instrument of social development and agent of social inclusion

    OpenAIRE

    Noêmia Lazzareschi

    2007-01-01

    Underveloped technology countries bare the hard consequences of the dependence vicious circle: they are dependents because they have delayed technology and they have delayed technology because they are dependents. Only with massive investiments in school education and in scientific and technological research they should break this vicious circle, greatly responsable for the social wounds and build a new social structure in which most people, if not all their population can, in fact, to perfor...

  9. [Socianalytical device: intervention instrument and data collection in qualitative research in nursing].

    Science.gov (United States)

    Spagnol, Carla Aparecida; L'Abbate, Solange; Monceau, Gilles; Jovic, Ljiljana

    2016-03-01

    The aims of this paper is to describe and to analyze the use of a socioanalytical device as a data collection too as well as a space of professional practice and work relations analysis, with nurses from a School Hospital of the Minas Gerais Federal University, Brazil. The qualitative approach was chosen to develop an intervention research with Institutional Analysis as theoretical and methodological framework. In the first stage of data collection, an exploratory research was carried out through a questionnaire and, in the second phase, a socianalytical device was built in 5 meetings that took place during two months. For the nurses, the analysis device has enabled personal and professional growth; to review positions; to exchange experience and to reflect on their own problems through the experience of other colleagues. We conclude that the socioanalytical device was a space for discussion, for analysis of professional practice and was the methodological strategy for data collection in this research. It has allowed the creation and recreation of forms of intervention, the production of knowledge and has improved quality of health work.

  10. The scientific and technological research as an instrument of social development and agent of social inclusion

    Directory of Open Access Journals (Sweden)

    Noêmia Lazzareschi

    2007-12-01

    Full Text Available Underveloped technology countries bare the hard consequences of the dependence vicious circle: they are dependents because they have delayed technology and they have delayed technology because they are dependents. Only with massive investiments in school education and in scientific and technological research they should break this vicious circle, greatly responsable for the social wounds and build a new social structure in which most people, if not all their population can, in fact, to perform their citizen’s rights, putting an end to the social exclusion.

  11. [Eating, nourishment and nutrition: instrumental analytic categories in the scientific research field].

    Science.gov (United States)

    da Veiga Soares Carvalho, Maria Cláudia; Luz, Madel Therezinha; Prado, Shirley Donizete

    2011-01-01

    Eating, nourishment or nutrition circulate in our culture as synonyms and thus do not account for the changes that occur in nourishment, which intended or unintended, have a hybridization pattern that represents a change of rules and food preferences. This paper aims to take these common sense conceptions as analytic categories for analyzing and interpreting research for the Humanities and Health Sciences in a theoretical perspective, through conceptualization. The food is associated with a natural function (biological), a concept in which nature is opposed to culture, and nourishment takes cultural meanings (symbolic), expressing the division of labor, wealth, and a historical and cultural creation through which one can study a society. One attributes to Nutrition a sense of rational action, derived from the constitution of this science in modernity, inserted in a historical process of scientific rationalization of eating and nourishing. We believe that through the practice of conceptualization in interdisciplinary research, which involves a shared space of knowledge, we can be less constrained by a unified theoretical model of learning and be freer to think about life issues.

  12. Nuclear instrumentation

    International Nuclear Information System (INIS)

    Weill, Jacky; Fabre, Rene.

    1981-01-01

    This article sums up the Research and Development effort at present being carried out in the five following fields of applications: Health physics and Radioprospection, Control of nuclear reactors, Plant control (preparation and reprocessing of the fuel, testing of nuclear substances, etc.), Research laboratory instrumentation, Detectors. It also sets the place of French industrial activities by means of an estimate of the French market, production and flow of trading with other countries [fr

  13. Developing a survey instrument to assess the readiness of primary care data, genetic and disease registries to conduct linked research: TRANSFoRm International Research Readiness (TIRRE survey instrument

    Directory of Open Access Journals (Sweden)

    Emily Leppenwell

    2013-05-01

    Full Text Available Background Clinical data are collected for routine care in family practice; there are also a growing number of genetic and cancer registry data repositories. The Translational Research and Patient Safety in Europe (TRANSFoRm project seeks to facilitate research using linked data from more than one source. We performed a requirements analysis which identified a wide range of data and business process requirements that need to be met before linking primary care and either genetic or disease registry data.Objectives To develop a survey to assess the readiness of data repositories to participate in linked research – the Transform International Research Readiness (TIRRE survey.Method We develop the questionnaire based on our requirement analysis; with questions at micro-, meso- and macro levels of granularity, study-specific questions about diabetes and gastro-oesophageal reflux disease (GORD, and research track record. The scope of the data required was extensive. We piloted this instrument, conducting ten preliminary telephone interviews to evaluate the response to the questionnaire.Results Using feedback gained from these interviews we revised the questionnaire; clarifying questions that were difficult to answer and utilising skip logic to create different series of questions for the various types of data repository. We simplified the questionnaire replacing free-text responses with yes/no or picking list options, wherever possible. We placed the final questionnaire online and encouraged its use (www.clininf.eu/jointirre/info.html.Conclusion Limited field testing suggests that TIRRE is capable of collecting comprehensive and relevant data about the suitability and readiness of data repositories to participate in linked data research.

  14. Innovative instrumentation

    International Nuclear Information System (INIS)

    Anon.

    1983-01-01

    At this year's particle physics conference at Brighton, a parallel session was given over to instrumentation and detector development. While this work is vital to the health of research and its continued progress, its share of prime international conference time is limited. Instrumentation can be innovative three times — first when a new idea is outlined, secondly when it is shown to be feasible, and finally when it becomes productive in a real experiment, amassing useful data rather than operational experience. Hyams' examples showed that it can take a long time for a new idea to filter through these successive stages, if it ever makes it at all

  15. Innovative instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1983-11-15

    At this year's particle physics conference at Brighton, a parallel session was given over to instrumentation and detector development. While this work is vital to the health of research and its continued progress, its share of prime international conference time is limited. Instrumentation can be innovative three times — first when a new idea is outlined, secondly when it is shown to be feasible, and finally when it becomes productive in a real experiment, amassing useful data rather than operational experience. Hyams' examples showed that it can take a long time for a new idea to filter through these successive stages, if it ever makes it at all.

  16. Comparative assessment of instrumentation and control (I and C) system architectures for research reactors

    International Nuclear Information System (INIS)

    Khalil, Rah Man; Heo, Gyun Young; Son, Han Seong; Kim, Young Ki; Park, Jae Kwan

    2012-01-01

    Application of digital I and C has increased in nuclear industry since last two decades but lack of experience, innovative and naive nature of technology and insufficient failure information raised questions on its use. The issues has been highlighted due to the use of digital I and C which were not relevant to analog. These are the potential weakness of digital systems for Common Cause Failure, threat to system security and reliability due to inter channel communication, need for highly integrated control room and difficulty to assess the digital I and C reliability. In the existing scenario, HANARO and JRTR have hybrid I and C systems (digital plus analog) whereas OPAL is fully digitalized. In order to authenticate the choice of fully digital I and C architecture for research reactor, it is required to perform assessment from risk point of view, cyber security as well other issues. The architecture assessment method and restrictions are discussed in the next part of article

  17. Comparative assessment of instrumentation and control (I and C) system architectures for research reactors

    Energy Technology Data Exchange (ETDEWEB)

    Khalil, Rah Man; Heo, Gyun Young [Kyung Hee Univ., Seoul (Korea, Republic of); Son, Han Seong [Joongbu Univ., Chungnam (Korea, Republic of); Kim, Young Ki; Park, Jae Kwan [KAERI, Daejeon (Korea, Republic of)

    2012-10-15

    Application of digital I and C has increased in nuclear industry since last two decades but lack of experience, innovative and naive nature of technology and insufficient failure information raised questions on its use. The issues has been highlighted due to the use of digital I and C which were not relevant to analog. These are the potential weakness of digital systems for Common Cause Failure, threat to system security and reliability due to inter channel communication, need for highly integrated control room and difficulty to assess the digital I and C reliability. In the existing scenario, HANARO and JRTR have hybrid I and C systems (digital plus analog) whereas OPAL is fully digitalized. In order to authenticate the choice of fully digital I and C architecture for research reactor, it is required to perform assessment from risk point of view, cyber security as well other issues. The architecture assessment method and restrictions are discussed in the next part of article.

  18. Preclinical molecular imaging: development of instrumentation for translational research with small laboratory animals.

    Science.gov (United States)

    Mejia, Jorge; Miranda, Ana Claudia Camargo; Durante, Ana Claudia Ranucci; Oliveira, Larissa Rolim de; Barboza, Marycel Rosa Felisa Figols de; Rosell, Katerin Taboada; Jardim, Daniele Pereira; Campos, Alexandre Holthausen; Reis, Marilia Alves Dos; Catanoso, Marcela Forli; Galvis-Alonso, Orfa Yineth; Cabral, Francisco Romero

    2016-01-01

    To present the result of upgrading a clinical gamma-camera to be used to obtain in vivo tomographic images of small animal organs, and its application to register cardiac, renal and neurological images. An updated version of the miniSPECT upgrading device was built, which is composed of mechanical, electronic and software subsystems. The device was attached to a Discovery VH (General Electric Healthcare) gamma-camera, which was retired from the clinical service and installed at the Centro de Imagem Pré-Clínica of the Hospital Israelita Albert Einstein. The combined system was characterized, determining operational parameters, such as spatial resolution, magnification, maximum acceptable target size, number of projections, and acquisition and reconstruction times. Images were obtained with 0.5mm spatial resolution, with acquisition and reconstruction times between 30 and 45 minutes, using iterative reconstruction with 10 to 20 iterations and 4 projection subsets. The system was validated acquiring in vivo tomographic images of the heart, kidneys and brain of normal animals (mice and adult rats), using the radiopharmaceuticals technetium-labeled hexakis-2-methoxy-isobutyl isonitrile (99mTc-Sestamibi), technetium-labeled dimercaptosuccinic acid (99mTc-DMSA) and technetium-labeled hexamethyl propyleneamine oxime (99mTc-HMPAO). This kind of application, which consists in the adaptation for an alternative objective of already existing instrumentation, resulted in a low-cost infrastructure option, allowing to carry out large scale in vivo studies with enhanced quality in several areas, such as neurology, nephrology, cardiology, among others. Apresentar o resultado da adaptação de uma gama câmara clínica para uso dedicado na obtenção de imagens tomográficas in vivo de órgãos de pequenos animais de experimentação, e de sua aplicação na obtenção de imagens cardíacas, renais e neurológicas. Foi construída uma versão atualizada do dispositivo de adapta

  19. Dreams In Jungian Psychology: The use of Dreams as an Instrument For Research, Diagnosis and Treatment of Social Phobia.

    Science.gov (United States)

    Khodarahimi, Siamak

    2009-10-01

    The significance of dreams has been explained in psychoanalysis, depth psychology and gestalt therapy. There are many guidelines in analytic psychology for dream interpretation and integration in clinical practice. The present study, based on the Jungian analytic model, incorporated dreams as an instrument for assessment of aetiology, the psychotherapy process and the outcome of treatment for social phobia within a clinical case study. This case study describes the use of dream analysis in treating a female youth with social phobia. The present findings supported the three stage paradigm efficiency in the Jungian model for dream working within a clinical setting, i.e. written details, reassembly with amplification and assimilation. It was indicated that childhood and infantile traumatic events, psychosexual development malfunctions, and inefficient coping skills for solving current life events were expressed in the patient's dreams. Dreams can reflect a patient's aetiology, needs, illness prognosis and psychotherapy outcome. Dreams are an instrument for the diagnosis, research and treatment of mental disturbances in a clinical setting.

  20. Nuclear medicine and imaging research. Instrumentation and quantitative methods of evaluation. Progress report, January 15, 1985-January 14, 1986

    International Nuclear Information System (INIS)

    Beck, R.N.; Cooper, M.D.

    1985-09-01

    This program of research addresses problems involving the basic science and technology of radioactive tracer methods as they relate to nuclear medicine and imaging. The broad goal is to develop new instruments and methods for image formation, processing, quantitation, and display, so as to maximize the diagnostic information per unit of absorbed radiation dose to the patient. These developments are designed to meet the needs imposed by new radiopharmaceuticals developed to solve specific biomedical problems, as well as to meet the instrumentation needs associated with radiopharmaceutical production and quantitative clinical feasibility studies of the brain with PET VI. Project I addresses problems associated with the quantitative imaging of single-photon emitters; Project II addresses similar problems associated with the quantitative imaging of positron emitters; Project III addresses methodological problems associated with the quantitative evaluation of the efficacy of diagnostic imaging procedures. The original proposal covered work to be carried out over the three-year contract period. This report covers progress made during Year Three. 36 refs., 1 tab

  1. Regulatory research of the PWR severe accident information needs and instrumentation availability for hydrogen control and management

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jae-Hong; Park, Gun-Chul; Suh, Kune Y.; Kang, Yun-Moon; Lee, Un-Jang; Oh, Se-Chul; Lee, Jin-Yong [Seoul Nationl Univ., Seoul (Korea, Republic of)

    1998-03-15

    During the current research period, we have set forth the methodology for identification of a severe accident, developed a framework for hydrogen management decision trees, and analyzed the literature on hydrogen management and experimental data for hydrogen bum. Specifically, we have summarized me results for information needs in a severe accident obtained in the U.S. and other countries, and applied the methodology to the reference plant YGN 3 and 4 as part of severe accident management. We have also examined the existing instruments in terms of their availability and survivability during a severe accident, and identified additionally needed information needs and instruments. We have identified dominant accident sequences for me reference plant YGN 3 and 4 to construct decision trees, and extracted available data from the IPE study of the plant. Based upon the data we have performed preliminary study on the decision tree and decision node. Last, we have examined various mechanisms for hydrogen generation and reIevant experimental data to predict me amount of hydrogen generation and governing factors in me process. We have also reviewed the hydrogen generation related models in the severe accident analysis.

  2. The Forsmark biotest basin. An instrument for environmental research. Experiences of large cooling water discharges in Sweden (1969-1993) and research perspectives for the future

    International Nuclear Information System (INIS)

    Snoeijs, P.

    1994-01-01

    This report presents the Biotest basin at Forsmark (Sweden) as an instrument for experimental environmental research, and indicates possibilities for its future use. the basin consists of a 1 km 2 artificial enclosure in the Baltic Sea that receives cooling water discharge from the Forsmark nuclear power plant. Cooling water discharge was initiated in 1980, and since then the basin has been serving as the main Swedish instrument for field studies on the effects of enhanced temperature and low-dose radioactivity on aquatic ecosystems. Environmental effects of large cooling water discharges from power plants to the sea have been studied at other sites in Sweden too, and for the sake of completeness of background information this report provides a survey and an extensive bibliography of all previous research on cooling water discharges in Sweden during the last 25 years. The aim of scientific research in the Biotest basin is to provide an independent academically-based assessment of the effects of the discharges of heat to the aquatic environment and of the pathways of pollutants through the ecosystems. Until now the research has mainly been describing the ecological effects of the cooling water flow through the basin under normal operation of the power plant. In the future it will be possible to manipulate the basin for large field experiments. An important perspective for the future is that of climatic change; the Forsmark Biotest basin provides excellent conditions for field studies on possible biological effects. This includes e.g. temperature effects on basic biological processes (growth, metabolism, reproduction etc.), population genetics, and combination effects of heat and toxic substances. 60 refs, 3 figs, 6 tabs

  3. Research on seamless development of surgical instruments based on biological mechanisms using CAD and 3D printer.

    Science.gov (United States)

    Yamamoto, Ikuo; Ota, Ren; Zhu, Rui; Lawn, Murray; Ishimatsu, Takakazu; Nagayasu, Takeshi; Yamasaki, Naoya; Takagi, Katsunori; Koji, Takehiko

    2015-01-01

    In the area of manufacturing surgical instruments, the ability to rapidly design, prototype and test surgical instruments is critical. This paper provides a simple case study of the rapid development of two bio-mechanism based surgical instruments which are ergonomic, aesthetic and were successfully designed, prototyped and conceptually tested in a very short period of time.

  4. A perspectiva pragmática nas pesquisas sobre prática instrumental: condições e implicações procedimentais A pragmatic perspective in instrumental practice research: conditions and procedural implications

    Directory of Open Access Journals (Sweden)

    Regina Antunes Teixeira dos Santos

    2009-01-01

    Full Text Available Pesquisas em prática instrumental evidenciam tendências que expressam certos aspectos de racionalidade calculada da ação e apontam para uma perspectiva pragmática de engajamento pessoal frente às situações de prática. Sistematizações sobre modos intencionais de proceder na prática instrumental em conexão com níveis de especialização músico-instrumental encontram-se não somente nos resultados dessas pesquisas, mas também implícitos nos conceitos de prática. Assim, o presente artigo discute a natureza e a finalidade das condições procedimentais implícitas nos conceitos e resultados de pesquisas em prática instrumental. Implicações procedimentais apresentam-se também nas discussões referentes à quantidade e a qualidade na prática, e justificam a existência de níveis diferenciados de especialização músico-instrumental na prática. O presente artigo aborda ainda a relação entre procedimentos e estratégias de prática.Research in instrumental practice has shown some trends that express certain aspects of calculated rationality, and point out to a pragmatic regime of personal commitment during practice. The systematization of the intentional procedures of the performer in order to improve and to refine one's music expertise level is present in research as well as in the concepts of instrumental practice. Thus, the present article discusses the nature and the goals of the procedimental conditions implicit in the concepts and research results in instrumental practice. Procedimental implications are also present in the discussion of the role of quantity and quality in the practice and justify the existence of different levels of instrumental expertise in the practice. This article also raises the relationship between procedures and strategies of practice.

  5. WE-G-BRB-00: NIH-Funded Research: Instrumental in the Pursuit of Clinical Trials and Technological Innovations

    International Nuclear Information System (INIS)

    2015-01-01

    Over the past 20 years the NIH has funded individual grants, program projects grants, and clinical trials which have been instrumental in advancing patient care. The ways that each grant mechanism lends itself to the different phases of translating research into clinical practice will be described. Major technological innovations, such as IMRT and proton therapy, have been advanced with R01-type and P01-type funding and will be discussed. Similarly, the role of program project grants in identifying and addressing key hypotheses on the potential of 3D conformal therapy, normal tissue-guided dose escalation and motion management will be described. An overview will be provided regarding how these technological innovations have been applied to multi-institutional NIH-sponsored trials. Finally, the panel will discuss regarding which research questions should be funded by the NIH to inspire the next advances in radiation therapy. Learning Objectives: Understand the different funding mechanisms of the NIH Learn about research advances that have led to innovation in delivery Review achievements due to NIH-funded program project grants in radiotherapy over the past 20 years Understand example advances achieved with multi-institutional clinical trials NIH

  6. Annual research review: Current limitations and future directions in MRI studies of child- and adult-onset developmental psychopathologies.

    Science.gov (United States)

    Horga, Guillermo; Kaur, Tejal; Peterson, Bradley S

    2014-06-01

    The widespread use of Magnetic Resonance Imaging (MRI) in the study of child- and adult-onset developmental psychopathologies has generated many investigations that have measured brain structure and function in vivo throughout development, often generating great excitement over our ability to visualize the living, developing brain using the attractive, even seductive images that these studies produce. Often lost in this excitement is the recognition that brain imaging generally, and MRI in particular, is simply a technology, one that does not fundamentally differ from any other technology, be it a blood test, a genotyping assay, a biochemical assay, or behavioral test. No technology alone can generate valid scientific findings. Rather, it is only technology coupled with a strong experimental design that can generate valid and reproducible findings that lead to new insights into the mechanisms of disease and therapeutic response. In this review we discuss selected studies to illustrate the most common and important limitations of MRI study designs as most commonly implemented thus far, as well as the misunderstanding that the interpretations of findings from those studies can create for our theories of developmental psychopathologies. Common limitations of MRI study designs are in large part responsible thus far for the generally poor reproducibility of findings across studies, poor generalizability to the larger population, failure to identify developmental trajectories, inability to distinguish causes from effects of illness, and poor ability to infer causal mechanisms in most MRI studies of developmental psychopathologies. For each of these limitations in study design and the difficulties they entail for the interpretation of findings, we discuss various approaches that numerous laboratories are now taking to address those difficulties, which have in common the yoking of brain imaging technologies to studies with inherently stronger designs that permit more valid

  7. FaNGaS: a New Instrument for Fast Neutron Gamma Spectroscopy at FRM II Research Reactor at Garching

    Energy Technology Data Exchange (ETDEWEB)

    Randriamalala, T.; Rossbach, M.; Genreith, C. [Institute of Energy and Climate Research, IEK-6: Nuclear Waste and Reactor Safety Fuel Cycle, Forchungszentrum Juelich GmbH in der Helmholtz-Gemeinshaft, 52428 Juelich (Germany); Revay, Zs.; Kudejova, P.; Soellradl, S.; Wagner, F.M. [Heinz Maier-Leibnitz Zentrum - MLZ, Technische Universitaet Muenchen, Lichtenbergstrasse 1, 85748 Garching (Germany)

    2015-07-01

    For the identification and quantification of actinides in radioactive packages, the non-destructive method of Prompt-Gamma Activation Analysis (PGAA) is applied. To investigate the inelastic (n, n 'γ) scattering, a new instrumentation was installed at the FRM II research reactor. It is designed to exploit the 10{sup 8} cm{sup -2}s{sup -1} neutrons at an average neutron energy of 1.9 MeV delivered by the SR10 beam line. The outgoing prompt γ-rays are measured utilizing a 50% efficiency HPGe detector. Since the cross sections are expected to be low for such a process, two related factors had to be taken into account for the design of the instrumentation: the high beam intensity at the sample position and the high signal-to-background ratio seen by the detector. Eventual low energy neutrons due to the multiple scatterings through the beam line can be minimized using collimators in the beam tube. This has also an effect to a prior neutrons and photons background reduction of the experimental environment. A higher efficiency of the counting can be achieved by the lowering of background at the detector. In this case, a heavy shielding for both neutrons and photons, is designed around the detector while optimizing the sample-detector distance. Monte-Carlo simulation studies were conducted to effectively design the fast neutron beam collimators and the detector shield. A detailed description of the setup characterization and results from simulations and experimental measurements will be discussed through this contribution. (authors)

  8. A low-cost MRI compatible keyboard

    DEFF Research Database (Denmark)

    Jensen, Martin Snejbjerg; Heggli, Ole Adrian; Alves da Mota, Patricia

    2017-01-01

    , presenting a challenging environment for playing an instrument. Here, we present an MRI-compatible polyphonic keyboard with a materials cost of 850 $, designed and tested for safe use in 3T (three Tesla) MRI-scanners. We describe design considerations, and prior work in the field. In addition, we provide...

  9. Developing a Research Instrument to Document Awareness, Knowledge, and Attitudes Regarding Breast Cancer and Early Detection Techniques for Pakistani Women: The Breast Cancer Inventory (BCI).

    Science.gov (United States)

    Naqvi, Atta Abbas; Zehra, Fatima; Ahmad, Rizwan; Ahmad, Niyaz

    2016-12-09

    There is a general hesitation in participation among Pakistani women when it comes to giving their responses in surveys related to breast cancer which may be due to the associated stigma and conservatism in society. We felt that no research instrument was able to extract information from the respondents to the extent it was needed for the successful execution of our study. The need to develop a research instrument tailored for Pakistani women was based upon the fact that most Pakistani women come from a conservative background and sometimes view this topic as provocative and believe discussing publicly about it as inappropriate. Existing research instruments exhibited a number of weaknesses during literature review. Therefore, using them may not be able to extract information concretely. A research instrument was, thus, developed exclusively. It was coined as, "breast cancer inventory (BCI)" by a panel of experts for executing a study aimed at documenting awareness, knowledge, and attitudes of Pakistani women regarding breast cancer and early detection techniques. The study is still in the data collection phase. The statistical analysis involved the Kaiser-Meyer-Olkin (KMO) measure and Bartlett's test for sampling adequacy. In addition, reliability analysis and exploratory factor analysis (EFA) were, also employed. This concept paper focuses on the development, piloting and validation of the BCI. It is the first research instrument which has high acceptability among Pakistani women and is able to extract adequate information from the respondents without causing embarrassment or unease.

  10. Developing a Research Instrument to Document Awareness, Knowledge, and Attitudes Regarding Breast Cancer and Early Detection Techniques for Pakistani Women: The Breast Cancer Inventory (BCI

    Directory of Open Access Journals (Sweden)

    Atta Abbas Naqvi

    2016-12-01

    Full Text Available There is a general hesitation in participation among Pakistani women when it comes to giving their responses in surveys related to breast cancer which may be due to the associated stigma and conservatism in society. We felt that no research instrument was able to extract information from the respondents to the extent it was needed for the successful execution of our study. The need to develop a research instrument tailored for Pakistani women was based upon the fact that most Pakistani women come from a conservative background and sometimes view this topic as provocative and believe discussing publicly about it as inappropriate. Existing research instruments exhibited a number of weaknesses during literature review. Therefore, using them may not be able to extract information concretely. A research instrument was, thus, developed exclusively. It was coined as, “breast cancer inventory (BCI” by a panel of experts for executing a study aimed at documenting awareness, knowledge, and attitudes of Pakistani women regarding breast cancer and early detection techniques. The study is still in the data collection phase. The statistical analysis involved the Kaiser-Meyer-Olkin (KMO measure and Bartlett’s test for sampling adequacy. In addition, reliability analysis and exploratory factor analysis (EFA were, also employed. This concept paper focuses on the development, piloting and validation of the BCI. It is the first research instrument which has high acceptability among Pakistani women and is able to extract adequate information from the respondents without causing embarrassment or unease.

  11. Head MRI

    Science.gov (United States)

    ... hearing aids Pins, hairpins, metal zippers, and similar metallic items Removable dental work How the Test will ... an MRI can make heart pacemakers and other implants not work as well. It can also cause ...

  12. Pediatric MRI

    Data.gov (United States)

    U.S. Department of Health & Human Services — The NIH Study of Normal Brain Development is a longitudinal study using anatomical MRI, diffusion tensor imaging (DTI), and MR spectroscopy (MRS) to map pediatric...

  13. Heat Flux Instrumentation Laboratory (HFIL)

    Data.gov (United States)

    Federal Laboratory Consortium — Description: The Heat Flux Instrumentation Laboratory is used to develop advanced, flexible, thin film gauge instrumentation for the Air Force Research Laboratory....

  14. The NetQuakes Project - Research-quality Seismic Data Transmitted via the Internet from Citizen-hosted Instruments (Invited)

    Science.gov (United States)

    Luetgert, J. H.; Oppenheimer, D. H.; Hamilton, J.

    2010-12-01

    The USGS seeks accelerograph spacing of 5-10 km in selected urban areas of the US to obtain spatially un-aliased recordings of strong ground motions during large earthquakes. These dense measurements will improve our ability to make rapid post-earthquake assessments of expected damage and contribute to the continuing development of engineering standards for construction. To achieve this goal the USGS and its university partners are deploying “NetQuakes” seismographs, designed to record moderate to large earthquakes from the near field to about 100 km. The instruments have tri-axial Colibrys 2005SF MEMS sensors, clip at 3g, and have 18-bit resolution. These instruments are uniquely designed for deployment in private homes, businesses, public buildings and schools where there is an existing Broadband connection to the Internet. The NetQuakes instruments connect to a local network using WiFi and then via the Internet to USGS servers to a) upload triggered accelerograms in miniSEED format, P arrival times, and computed peak ground motion parameters immediately after an earthquake; b) download software updates; c) respond to requests for log files, execute UNIX scripts, and upload waveforms from long-term memory for quakes with peak motions below the trigger threshold; d) send state-of-health (SOH) information in XML format every 10 minutes; and e) synchronize instrument clocks to 1ms accuracy using the Network Time Protocol. NetQuakes instruments cost little to operate and save about $600/yr/site compared to instruments that transmit data via leased telemetry. After learning about the project through press releases, thousands of citizens have registered to host an instrument at http://earthquake.usgs.gov/netquakes using a Google Map interface that depicts where we seek instrument sites. The website also provides NetQuakes hosts access to waveform images recorded by instruments installed in their building. Since 3/2009, the NetQuakes project has installed over 100

  15. Research within the coordinated programme on investigation of maintenance of nuclear instrumentation in developing countries. Latin America

    International Nuclear Information System (INIS)

    Guzman-Acevedo, C.

    1980-06-01

    The situation in Peru with regard to the maintenance and repair of instruments used in nuclear medicine is presented. On the basis of responses to questionnaires it appears that 56 instruments for nuclear medicine are in use in the country, almost exclusively in the capital Lima. The average age of the instruments is 9.5 years. They are in use about 16.4% of the possible time. The development of nuclear medicine in Peru is in its initial stages and difficulties encountered arise both from the lack of training and experience in nuclear medicine on the part of the medical personnel as well as lack of experience of the technicians responsible for instrument maintenance. Practically no preventive maintenance ever takes place; action is only taken when an instrument breaks down. Various suggestions are made in order to attempt an improvement of the situation

  16. Belgium and France join forces in measuring instrument research. SCK-CEN and CEA are jointly developing an innovative type of gamma detector

    International Nuclear Information System (INIS)

    Vermeeren, L.

    2011-01-01

    Real-time monitoring is extremely important to accurately interpret irradiation experiments in research reactors. SCK-CEN has years of expertise in developing sensors to monitor neutron flux, temperature, gamma radiation, etc. It has been collaborating with the CEA since 2006. Both partners share research and research results in the Laboratoire Commun de Instrumentation. Recently, a joint patent application was made for a new type of sensor to measure gamma rays.

  17. Design, fabrication and irradiation test report on HANARO instrumented capsule (03M-06U) for researches of universities in 2003

    International Nuclear Information System (INIS)

    Choo, K. N.; Kim, B. G.; Kang, Y. H.; Choi, M. H.; Cho, M. S.; Son, J. M.; Shin, Y. T.; Park, S. J.

    2005-03-01

    As a part of 2003 project for active utilization of HANARO, an instrumented capsule (03M-06U) was designed, fabricated and irradiated for the irradiation test of various nuclear materials under irradiation conditions requested by external researchers from universities. The basic structure of 03M-06U capsule was based on the 00M-01U, 01M-05U and 02M-05U capsules successfully irradiated in HANARO as 2000, 2001 and 2002 projects. However, because of the limited number of specimens and budget of 4 universities, the remained space of the capsule was charged with KAERI specimens for the development of the precise temperature control technology under irradiation. The material of the specimens is mainly Fe-based alloys partially mixed with Zr, Al and Cu-Ag alloys. The capsule is composed of 5 stages having many kinds of specimens and independent electric heater in each stage. During the irradiation test, the temperature of the specimens and the thermal/fast neutron fluences were measured by 14 thermocouples and 5 sets of Ni-Ti-Fe neutron fluence monitors installed in the capsule. Various types of specimens such as tensile, Charpy, TEM, toughness, electrical resistance specimens were inserted in the capsule. The capsule was firstly irradiated in the CT test hole of HANARO of 30MW thermal output at 275∼500±10 .deg. C up to a fast neutron fluence of 5.4 x 10 20 (n/cm 2 ) (E>1.0MeV). The obtained results will be very valuable for the related researches of the users

  18. Performing the Super Instrument

    DEFF Research Database (Denmark)

    Kallionpaa, Maria

    2016-01-01

    can empower performers by producing super instrument works that allow the concert instrument to become an ensemble controlled by a single player. The existing instrumental skills of the performer can be multiplied and the qualities of regular acoustic instruments extended or modified. Such a situation......The genre of contemporary classical music has seen significant innovation and research related to new super, hyper, and hybrid instruments, which opens up a vast palette of expressive potential. An increasing number of composers, performers, instrument designers, engineers, and computer programmers...... have become interested in different ways of “supersizing” acoustic instruments in order to open up previously-unheard instrumental sounds. Super instruments vary a great deal but each has a transformative effect on the identity and performance practice of the performing musician. Furthermore, composers...

  19. Contrast agents for MRI

    International Nuclear Information System (INIS)

    Bonnemain, B.

    1994-01-01

    Contrast agents MRI (Magnetic Resonance Imaging) have been developed to improve the diagnostic information obtained by this technic. They mainly interact on T1 and T2 parameters and increase consequently normal to abnormal tissues contrast. The paramagnetic agents which mainly act on longitudinal relaxation rate (T1) are gadolinium complexes for which stability is the main parameter to avoid any release of free gadolinium. The superparamagnetic agents that decrease signal intensity by an effect on transversal relaxation rate (T2) are developed for liver, digestive and lymph node imaging. Many area of research are now opened for optimal use of present and future contrast agents in MRI. (author). 28 refs., 4 tabs

  20. Networked Instrumentation Element

    Data.gov (United States)

    National Aeronautics and Space Administration — Armstrong researchers have developed a networked instrumentation system that connects modern experimental payloads to existing analog and digital communications...

  1. Portable MRI

    Energy Technology Data Exchange (ETDEWEB)

    Espy, Michelle A. [Los Alamos National Laboratory

    2012-06-29

    This project proposes to: (1) provide the power of MRI to situations where it presently isn't available; (2) perform the engineering required to move from lab to a functional prototype; and (3) leverage significant existing infrastructure and capability in ultra-low field MRI. The reasons for doing this: (1) MRI is the most powerful tool for imaging soft-tissue (e.g. brain); (2) Billions don't have access due to cost or safety issues; (3) metal will heat/move in high magnetic fields; (4) Millions of cases of traumatic brain injury in US alone; (5) even more of non-traumatic brain injury; (6) (e.g. stroke, infection, chemical exposure); (7) Need for early diagnostic; (8) 'Signature' wound of recent conflicts; (9) 22% of injuries; (10) Implications for post-traumatic stress disorder; and (11) chronic traumatic encephalopathy.

  2. Portable MRI

    International Nuclear Information System (INIS)

    Espy, Michelle A.

    2012-01-01

    This project proposes to: (1) provide the power of MRI to situations where it presently isn't available; (2) perform the engineering required to move from lab to a functional prototype; and (3) leverage significant existing infrastructure and capability in ultra-low field MRI. The reasons for doing this: (1) MRI is the most powerful tool for imaging soft-tissue (e.g. brain); (2) Billions don't have access due to cost or safety issues; (3) metal will heat/move in high magnetic fields; (4) Millions of cases of traumatic brain injury in US alone; (5) even more of non-traumatic brain injury; (6) (e.g. stroke, infection, chemical exposure); (7) Need for early diagnostic; (8) 'Signature' wound of recent conflicts; (9) 22% of injuries; (10) Implications for post-traumatic stress disorder; and (11) chronic traumatic encephalopathy.

  3. The MacArthur Competence Assessment Tool-Fitness to Plead: a preliminary evaluation of a research instrument for assessing fitness to plead in England and Wales.

    Science.gov (United States)

    Akinkunmi, Akintunde A

    2002-01-01

    This study concerns the preliminary evaluation of an instrument, the MacArthur Competence Assessment Tool-Fitness to Plead (MacCAT-FP), for assessing competence to stand trial, according to the legal requirements in England and Wales. The purposes of the study were to ascertain whether the instrument can be administered practically to groups of prisoners, both those with mental illness and those without; to examine its internal consistency and interrater reliability; to determine whether it can distinguish between fit and unfit individuals, as judged by expert forensic psychiatrists; and to discover whether it is sensitive to changes over time. The instrument was administered to two groups of remanded prisoners: those transferred to psychiatric units for treatment and those without mental illness. In addition to the MacCAT-FP, scales measuring symptom severity and IQ were administered to all participants. Results suggest that the instrument is practical, with good internal consistency and interrater reliability. The correlation of scores with psychiatrists' opinions as to fitness was 0.77. Scores of unfit patients were significantly different from those of fit individuals. The instrument was able to detect significant differences in scores over time. It is suggested that once the instrument has been further validated for research purposes, it may be developed for clinical application.

  4. Combined PET/MRI

    DEFF Research Database (Denmark)

    Bailey, D L; Pichler, B J; Gückel, B

    2018-01-01

    The 6th annual meeting to address key issues in positron emission tomography (PET)/magnetic resonance imaging (MRI) was held again in Tübingen, Germany, from March 27 to 29, 2017. Over three days of invited plenary lectures, round table discussions and dialogue board deliberations, participants c...... of response to pharmacological interventions and therapies. As such, PET/MRI is a key to advancing medicine and patient care.......The 6th annual meeting to address key issues in positron emission tomography (PET)/magnetic resonance imaging (MRI) was held again in Tübingen, Germany, from March 27 to 29, 2017. Over three days of invited plenary lectures, round table discussions and dialogue board deliberations, participants...... critically assessed the current state of PET/MRI, both clinically and as a research tool, and attempted to chart future directions. The meeting addressed the use of PET/MRI and workflows in oncology, neurosciences, infection, inflammation and chronic pain syndromes, as well as deeper discussions about how...

  5. Instrumentation maintenance

    International Nuclear Information System (INIS)

    Mack, D.A.

    1976-09-01

    It is essential to any research activity that accurate and efficient measurements be made for the experimental parameters under consideration for each individual experiment or test. Satisfactory measurements in turn depend upon having the necessary instruments and the capability of ensuring that they are performing within their intended specifications. This latter requirement can only be achieved by providing an adequate maintenance facility, staffed with personnel competent to understand the problems associated with instrument adjustment and repair. The Instrument Repair Shop at the Lawrence Berkeley Laboratory is designed to achieve this end. The organization, staffing and operation of this system is discussed. Maintenance policy should be based on studies of (1) preventive vs. catastrophic maintenance, (2) records indicating when equipment should be replaced rather than repaired and (3) priorities established to indicate the order in which equipment should be repaired. Upon establishing a workable maintenance policy, the staff should be instructed so that they may provide appropriate scheduled preventive maintenance, calibration and corrective procedures, and emergency repairs. The education, training and experience of the maintenance staff is discussed along with the organization for an efficient operation. The layout of the various repair shops is described in the light of laboratory space and financial constraints

  6. Instrumentation for medical diagnosis and research with radionuclides in the developing countries. Progress report, June 1, 1977--May 31, 1978

    Energy Technology Data Exchange (ETDEWEB)

    Dudley, R.A.

    1978-07-01

    This project seeks to bring about a more effective use of nuclear instruments in medical applications of radionuclides in developing countries by facilitating selection of appropriate applications, by stimulating the design of instruments capable of performing these applications satisfactorily under the conditions prevailing, and by encouraging improved maintenance. A pilot cost-effectiveness analysis of nuclear medicine applications has been completed, suggesting two topics for further investigation and demonstrating that such analyses can yield useful insights. In the realm of instrument design, we have further developed our prototype well scintillation counter, provided three such instruments for tests in the field, and encouraged its production by others. In addition, we have examined design issues for liquid scintillation counters, radiorespirometry counting devices, whole-body counters, and electrical power supplies. We have completed a survey of maintenance in 8 countries in Southeast Asia and are analyzing the results. Preparations are underway for surveys in three further regions.

  7. Fetal MRI

    International Nuclear Information System (INIS)

    Prayer, D.; Brugger, P.C.

    2004-01-01

    New, ultrafast sequences have made it possible to obtain MR images of the fetus without maternal sedation or immobilization of the fetus itself. While fetal MRI began as an adjunct to ultrasound, it has now been shown that MRI can provide additional information that may change prognosis, the management of pregnancy, or the treatment of the newborn child. It is of particular value in the assessment of malformations of the central nervous system. The steady development and adaptation of MR-sequences to the needs of fetal imaging has led to new indications that can support prognostic and therapeutic decisions. (orig.)

  8. Interventional MRI

    Energy Technology Data Exchange (ETDEWEB)

    Harada, Junta; Dohi, Michiko; Yoshihiro, Akiko; Mogami, Takuji; Kuwada, Tomoko; Nakata, Norio [Jikei Univ., Chiba (Japan). Kashiwa Hospital

    2000-06-01

    Open type MR system and fast sequence is now available and MRI becomes a new modality for interventional Radiology, including biopsy, drainage operation, and monitoring for minimally invasive therapy. Experimental studies of temperature monitoring were performed under hot and cold status. Signal changes of porcine disc and meat under microwave and laser ablation were observed as low signal area by signal intensity method. Using proton chemical shift method, signal change by laser ablation was displaced color imaging and correlated with thermometric temperature measurement. The very T2 relaxation time of ice affords excellent contrast between ice and surrounding gelatin tissue allowing acute depiction of the extent of the iceball under MRI. (author)

  9. Fetal MRI

    Energy Technology Data Exchange (ETDEWEB)

    Prayer, D.; Brugger, P.C. [University Hospital of Vienna (Austria). Division of Neuroradiology

    2004-07-01

    New, ultrafast sequences have made it possible to obtain MR images of the fetus without maternal sedation or immobilization of the fetus itself. While fetal MRI began as an adjunct to ultrasound, it has now been shown that MRI can provide additional information that may change prognosis, the management of pregnancy, or the treatment of the newborn child. It is of particular value in the assessment of malformations of the central nervous system. The steady development and adaptation of MR-sequences to the needs of fetal imaging has led to new indications that can support prognostic and therapeutic decisions. (orig.)

  10. Outcome in adolescent idiopathic scoliosis after brace treatment and surgery assessed by means of the Scoliosis Research Society Instrument 24.

    Science.gov (United States)

    Weigert, Karen Petra; Nygaard, Linda Marie; Christensen, Finn Bjarke; Hansen, Ebbe Stender; Bünger, Cody

    2006-07-01

    A retrospectively designed long-term follow-up study of adolescent idiopathic scoliosis (AIS) patients who had completed treatment, of at least 2 years, by means of brace, surgery, or both brace and surgery. This study is to assess the outcome after treatment for AIS by means of the Scoliosis Research Society Outcome Instrument 24 (SRS 24). One hundred and eighteen AIS patients (99 females and 19 males), treated at the Aarhus University Hospital from January 1, 1987 to December 31, 1997, were investigated with at least 2 years follow-up at the time of receiving a posted self-administered questionnaire. Forty-four patients were treated with Boston brace (B) only, 41 patients had surgery (S), and 33 patients were treated both with brace and surgery (BS). The Cobb angles of the three treatment groups did not differ significantly after completed treatment. The outcome in terms of the total SRS 24 score was not significantly different among the three groups. B patients had a significantly better general (not treatment related) self-image and higher general activity level than the total group of surgically treated patients, while surgically treated patients scored significantly better in post-treatment self-image and satisfaction. Comparing B with BS we found a significantly higher general activity level in B patients, while the BS group had significantly higher satisfaction. There were no significant differences between BS and S patients in any of the domain scores. All treatment groups scored "fair or better" in all domain scores of the SRS 24 questionnaire, except in post-treatment function, where all groups scored worse than "fair". Improvement of appearance by means of surgical correction increases mean scores for post-treatment self-image and post-treatment satisfaction. Double-treatment by brace and surgery does not appear to jeopardize a good final outcome.

  11. Pediatric patient-reported outcome instruments for research to support medical product labeling: report of the ISPOR PRO good research practices for the assessment of children and adolescents task force.

    Science.gov (United States)

    Matza, Louis S; Patrick, Donald L; Riley, Anne W; Alexander, John J; Rajmil, Luis; Pleil, Andreas M; Bullinger, Monika

    2013-06-01

    Patient-reported outcome (PRO) instruments for children and adolescents are often included in clinical trials with the intention of collecting data to support claims in a medical product label. The purpose of the current task force report is to recommend good practices for pediatric PRO research that is conducted to inform regulatory decision making and support claims made in medical product labeling. The recommendations are based on the consensus of an interdisciplinary group of researchers who were assembled for a task force associated with the International Society for Pharmacoeconomics and Outcomes Research (ISPOR). In those areas in which supporting evidence is limited or in which general principles may not apply to every situation, this task force report identifies factors to consider when making decisions about the design and use of pediatric PRO instruments, while highlighting issues that require further research. Five good research practices are discussed: 1) Consider developmental differences and determine age-based criteria for PRO administration: Four age groups are discussed on the basis of previous research (<5 years old, 5-7 years, 8-11 years, and 12-18 years). These age groups are recommended as a starting point when making decisions, but they will not fit all PRO instruments or the developmental stage of every child. Specific age ranges should be determined individually for each population and PRO instrument. 2) Establish content validity of pediatric PRO instruments: This section discusses the advantages of using children as content experts, as well as strategies for concept elicitation and cognitive interviews with children. 3) Determine whether an informant-reported outcome instrument is necessary: The distinction between two types of informant-reported measures (proxy vs. observational) is discussed, and recommendations are provided. 4) Ensure that the instrument is designed and formatted appropriately for the target age group. Factors to

  12. Proceeding of the Scientific Meeting and Presentation on Basic Research of Nuclear Science and Technology: Book I. Physics, Reactor Physics and Nuclear Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    The proceeding contains papers presented on Scientific Meeting and Presentation on on Basic Research of Nuclear Science and Technology, held in Yogyakarta, 25-27 April 1995. This proceeding is part one from two books published for the meeting contains papers on Physics, Reactor Physics and Nuclear Instrumentation as results of research activities in National Atomic Energy Agency. There are 39 papers indexed individually. (ID)

  13. Proceeding of the Scientific Meeting and Presentation on Basic Research in Nuclear Science and Technology. Part I : Physics, Reactor Physics and Nuclear Instrumentation

    International Nuclear Information System (INIS)

    Sudjatmoko; Karmanto, Eko Edy; Supartini, Endang

    1996-04-01

    Scientific Meeting and Presentation on Basic Research in Nuclear Science and Technology is a routine activity was held by PPNY BATAN for monitoring the research Activity which achieved in BATAN. The Proceeding contains a proposal about basic which has physics; reactor physics and nuclear instrumentation. This proceedings is the first part from two part which published in series. There are 33 articles which have separated index

  14. Research and engineering application of coordinated instrumentation control and protection technology between reactor and steam turbine generator on nuclear power plant

    International Nuclear Information System (INIS)

    Sun Xingdong

    2014-01-01

    The coordinated instrumentation control and protection technology between reactor and steam turbine generator (TG) usually is very significant and complicated for a new construction of nuclear power plant, because it carries the safety, economy and availability of nuclear power plant. Based on successful practice of a nuclear power plant, the experience on interface design and hardware architecture of coordinated instrumentation control and protection technology between reactor and steam turbine generator was abstracted and researched. In this paper, the key points and engineering experience were introduced to give the helpful instructions for the new project. (author)

  15. Availability analysis of the nuclear instrumentation of a research reactor; Analise da disponibilidade da instrumentacao nuclear de um reator de pesquisa

    Energy Technology Data Exchange (ETDEWEB)

    Vianna Filho, Alfredo Marques

    2016-07-01

    The maintenance of systems and equipment is a central question related to Production Engineering. Although systems are not fully reliable, it is often necessary to minimize the failure occurrence likelihood. The failures occurrences can have disastrous consequences during a plane flight or operation of a nuclear power plant. The elaboration of a maintenance plan has as objective the prevention and recovery from system failures, increasing reliability and reducing the cost of unplanned shutdowns. It is also important to consider the issues related to organizations safety, especially those dealing with dangerous technologies. The objective of this thesis is to propose a method for maintenance analysis of a nuclear research reactor, using a socio-technical approach, and focused on existing conditions in Brazil. The research reactor studied belongs to the federal government and it is located in the city of Rio de Janeiro. The specific objective of this thesis is to develop the availability analysis of one of the principal systems of the research reactor, the nuclear instrumentation system. In this analysis, were taken into account not only the technical aspects of the modules related to nuclear instrumentation system, but also the human and organizational factors that could affect the availability of the nuclear instrumentation system. The results showed the influence of these factors on the availability of the nuclear instrumentation system. (author)

  16. Tsengwen Reservoir Watershed Hydrological Flood Simulation Under Global Climate Change Using the 20 km Mesh Meteorological Research Institute Atmospheric General Circulation Model (MRI-AGCM

    Directory of Open Access Journals (Sweden)

    Nobuaki Kimura

    2014-01-01

    Full Text Available Severe rainstorms have occurred more frequently in Taiwan over the last decade. To understand the flood characteristics of a local region under climate change, a hydrological model simulation was conducted for the Tsengwen Reservoir watershed. The model employed was the Integrated Flood Analysis System (IFAS, which has a conceptual, distributed rainfall-runoff analysis module and a GIS data-input function. The high-resolution rainfall data for flood simulation was categorized into three terms: 1979 - 2003 (Present, 2015 - 2039 (Near-future, and 2075 - 2099 (Future, provided by the Meteorological Research Institute atmospheric general circulation model (MRI-AGCM. Ten extreme rainfall (top ten events were selected for each term in descending order of total precipitation volume. Due to the small watershed area the MRI-AGCM3.2S data was downsized into higher resolution data using the Weather Research and Forecasting Model. The simulated discharges revealed that most of the Near-future and Future peaks caused by extreme rainfall increased compared to the Present peak. These ratios were 0.8 - 1.6 (Near-future/Present and 0.9 - 2.2 (Future/Present, respectively. Additionally, we evaluated how these future discharges would affect the reservoir¡¦s flood control capacity, specifically the excess water volume required to be stored while maintaining dam releases up to the dam¡¦s spillway capacity or the discharge peak design for flood prevention. The results for the top ten events show that the excess water for the Future term exceeded the reservoir¡¦s flood control capacity and was approximately 79.6 - 87.5% of the total reservoir maximum capacity for the discharge peak design scenario.

  17. Radioisotope instruments

    CERN Document Server

    Cameron, J F; Silverleaf, D J

    1971-01-01

    International Series of Monographs in Nuclear Energy, Volume 107: Radioisotope Instruments, Part 1 focuses on the design and applications of instruments based on the radiation released by radioactive substances. The book first offers information on the physical basis of radioisotope instruments; technical and economic advantages of radioisotope instruments; and radiation hazard. The manuscript then discusses commercial radioisotope instruments, including radiation sources and detectors, computing and control units, and measuring heads. The text describes the applications of radioisotop

  18. Status of safeguards instrumentation

    International Nuclear Information System (INIS)

    Higinbotham, W.A.

    The International Atomic Energy Agency is performing safeguards at some nuclear power reactors, 50 bulk processing facilities, and 170 research facilities. Its verification activities require the use of instruments to measure nuclear materials and of surveillance instruments to maintain continuity of knowledge of the locations of nuclear materials. Instruments that are in use and under development to measure weight, volume, concentration, and isotopic composition of nuclear materials, and the major surveillance instruments, are described in connection with their uses at representative nuclear facilities. The current status of safeguards instrumentation and the needs for future development are discussed

  19. Prevalence Estimation and Validation of New Instruments in Psychiatric Research: An Application of Latent Class Analysis and Sensitivity Analysis

    Science.gov (United States)

    Pence, Brian Wells; Miller, William C.; Gaynes, Bradley N.

    2009-01-01

    Prevalence and validation studies rely on imperfect reference standard (RS) diagnostic instruments that can bias prevalence and test characteristic estimates. The authors illustrate 2 methods to account for RS misclassification. Latent class analysis (LCA) combines information from multiple imperfect measures of an unmeasurable latent condition to…

  20. Testing Differential Effects of Computer-Based, Web-Based and Paper-Based Administration of Questionnaire Research Instruments

    Science.gov (United States)

    Hardre, Patricia L.; Crowson, H. Michael; Xie, Kui; Ly, Cong

    2007-01-01

    Translation of questionnaire instruments to digital administration systems, both self-contained and web-based, is widespread and increasing daily. However, the literature is lean on controlled empirical studies investigating the potential for differential effects of administrative methods. In this study, two university student samples were…

  1. Multiple Homicide as a Function of Prisonization and Concurrent Instrumental Violence: Testing an Interactive Model--A Research Note

    Science.gov (United States)

    DeLisi, Matt; Walters, Glenn D.

    2011-01-01

    Prisonization (as measured by number of prior incarcerations) and concurrent instrumental offending (as measured by contemporaneous kidnapping, rape, robbery, and burglary offenses) were found to interact in 160 multiple-homicide offenders and 494 single-homicide offenders. Controlling for age, gender, race, criminal history, prior incarcerations,…

  2. Twenty-fifth water reactor safety information meeting: Proceedings. Volume 3: Thermal hydraulic research and codes; Digital instrumentation and control; Structural performance

    International Nuclear Information System (INIS)

    Monteleone, S.

    1998-04-01

    This three-volume report contains papers presented at the conference. The papers are printed in the order of their presentation in each session and describe progress and results of programs in nuclear safety research conducted in this country and abroad. Foreign participation in the meeting included papers presented by researchers from France, Japan, Norway, and Russia. The titles of the papers and the names of the authors have been updated and may differ from those that appeared in the final program of the meeting. This volume contains the following: (1) thermal hydraulic research and codes; (2) digital instrumentation and control; (3) structural performance

  3. MRI angiography

    International Nuclear Information System (INIS)

    Poncelet, B.; Baleriiaux, D.; struyven, J.; Segebarth, C.

    1989-01-01

    In MRI angiography two basis images are measured which only differ by the signal intensity of the flowing blood in the vessels. Subtraction of these two images produces a high contrast-to-noise representation of the vessels. Contrast between stationary tissues and flowing blood is changed, for one image compared to the second one, using a selective modification of the phase of the signal from the flowing blood, and/or using a selective modification of its longitudinal magnetization: The macroscopic spin motions along the selection and the measurement gradient directions affect the phase of the nuclear signal; assuming constant velocity, the phase is proportional to the velocity and to the first moment of the gradient waveforms applied. This work concentrates on the generarion of MRI angiograms, following a phase-based approach, of the carotid bifurcation and of different intracranical regions including the carotid syphon and the circle of Willis. (author). 21 refs.; 3 figs

  4. MRI zoo

    DEFF Research Database (Denmark)

    Laustsen, Christoffer

    The basic idea was to use MRI to produce a sequence of 3D gray scale image slices of various animals, subsequentlyimaged with a clinical CT system. For this purpose, these animals were used: toad, lungfish, python snake and a horseshoe crab. Each animal was sacrificed according to standard...... visually inspected, both in 2D and 3D, and compared with photographs and anatomy atlases found at library and on the internet....

  5. Software for an automated processing system for radioisotope information from multichannel radiodiagnostic instruments

    International Nuclear Information System (INIS)

    Zelenin, P.E.; Meier, V.P.

    1985-01-01

    The SAORI-01 system for the automated processing of radioisotope information is designed for the collection, processing, and representation of information coming from gamma chambers and multichannel radiodiagnostic instruments (MRI) and is basically oriented toward the radiodiagnostic laboratories of major multidisciplinary hospitals and scientific-research institutes. The functional characteristics of the basic software are discussed, and permits performance of the following functions: collection of information regarding MRI; processing and representation of recorded information; storage of patient files on magnetic carriers; and writing of special processing programs in the FORTRAN and BASIC high-level language

  6. A multicenter study analyzing the relationship of a standardized radiographic scoring system of adolescent idiopathic scoliosis and the Scoliosis Research Society outcomes instrument.

    Science.gov (United States)

    Wilson, Philip L; Newton, Peter O; Wenger, Dennis R; Haher, Thomas; Merola, Andrew; Lenke, Larry; Lowe, Thomas; Clements, David; Betz, Randy

    2002-09-15

    A multicenter study examining the association between radiographic and outcomes measures in adolescent idiopathic scoliosis. To evaluate the association between an objective radiographic scoring system and patient quality of life measures as determined by the Scoliosis Research Society outcomes instrument. Although surgical correction of scoliosis has been reported to be positively correlated with patient outcomes, studies to date have been unable to demonstrate an association between radiographic measures of deformity and outcomes measures in patients with adolescent idiopathic scoliosis. A standardized radiographic deformity scoring system and the Scoliosis Research Society outcome tool were used prospectively in seven scoliosis centers to collect data on patients with adolescent idiopathic scoliosis. A total of 354 data points for 265 patients consisting of those with nonoperative or preoperative curves >or=10 degrees, as well as those with surgically treated curves, were analyzed. Correlation analysis was performed to identify significant relationships between any of the radiographic measures, the Harms Study Group radiographic deformity scores (total, sagittal, coronal), and the seven Scoliosis Research Society outcome domains (Total Pain, General Self-Image, General Function, Activity, Postoperative Self-Image, Postoperative Function, and Satisfaction) as well as Scoliosis Research Society outcomes instrument total scores. Radiographic measures that were identified as significantly correlated with Scoliosis Research Society outcome scores were then entered into a stepwise regression analysis. The coronal measures of thoracic curve and lumbar curve magnitude were found to be significantly correlated with the Total Pain, General Self-Image, and total Scoliosis Research Society scores (P Society domain and total scores. No radiographic measures taken after surgery were significantly correlated with the postoperative domains of the Scoliosis Research Society

  7. Instrumental interaction

    OpenAIRE

    Luciani , Annie

    2007-01-01

    International audience; The expression instrumental interaction as been introduced by Claude Cadoz to identify a human-object interaction during which a human manipulates a physical object - an instrument - in order to perform a manual task. Classical examples of instrumental interaction are all the professional manual tasks: playing violin, cutting fabrics by hand, moulding a paste, etc.... Instrumental interaction differs from other types of interaction (called symbolic or iconic interactio...

  8. Measurement Instrument for Scientific Teaching (MIST): A Tool to Measure the Frequencies of Research-Based Teaching Practices in Undergraduate Science Courses.

    Science.gov (United States)

    Durham, Mary F; Knight, Jennifer K; Couch, Brian A

    2017-01-01

    The Scientific Teaching (ST) pedagogical framework provides various approaches for science instructors to teach in a way that more closely emulates how science is practiced by actively and inclusively engaging students in their own learning and by making instructional decisions based on student performance data. Fully understanding the impact of ST requires having mechanisms to quantify its implementation. While many useful instruments exist to document teaching practices, these instruments only partially align with the range of practices specified by ST, as described in a recently published taxonomy. Here, we describe the development, validation, and implementation of the Measurement Instrument for Scientific Teaching (MIST), a survey derived from the ST taxonomy and designed to gauge the frequencies of ST practices in undergraduate science courses. MIST showed acceptable validity and reliability based on results from 7767 students in 87 courses at nine institutions. We used factor analyses to identify eight subcategories of ST practices and used these categories to develop a short version of the instrument amenable to joint administration with other research instruments. We further discuss how MIST can be used by instructors, departments, researchers, and professional development programs to quantify and track changes in ST practices. © 2017 M. F. Durham et al. CBE—Life Sciences Education © 2017 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  9. Japan Meteorological Agency/Meteorological Research Institute-Coupled Prediction System version 2 (JMA/MRI-CPS2): atmosphere-land-ocean-sea ice coupled prediction system for operational seasonal forecasting

    Science.gov (United States)

    Takaya, Yuhei; Hirahara, Shoji; Yasuda, Tamaki; Matsueda, Satoko; Toyoda, Takahiro; Fujii, Yosuke; Sugimoto, Hiroyuki; Matsukawa, Chihiro; Ishikawa, Ichiro; Mori, Hirotoshi; Nagasawa, Ryoji; Kubo, Yutaro; Adachi, Noriyuki; Yamanaka, Goro; Kuragano, Tsurane; Shimpo, Akihiko; Maeda, Shuhei; Ose, Tomoaki

    2018-02-01

    This paper describes the Japan Meteorological Agency/Meteorological Research Institute-Coupled Prediction System version 2 (JMA/MRI-CPS2), which was put into operation in June 2015 for the purpose of performing seasonal predictions. JMA/MRI-CPS2 has various upgrades from its predecessor, JMA/MRI-CPS1, including improved resolution and physics in its atmospheric and oceanic components, introduction of an interactive sea-ice model and realistic initialization of its land component. Verification of extensive re-forecasts covering a 30-year period (1981-2010) demonstrates that JMA/MRI-CPS2 possesses improved seasonal predictive skills for both atmospheric and oceanic interannual variability as well as key coupled variability such as the El Niño-Southern Oscillation (ENSO). For ENSO prediction, the new system better represents the forecast uncertainty and transition/duration of ENSO phases. Our analysis suggests that the enhanced predictive skills are attributable to incremental improvements resulting from all of the changes, as is apparent in the beneficial effects of sea-ice coupling and land initialization on 2-m temperature predictions. JMA/MRI-CPS2 is capable of reasonably representing the seasonal cycle and secular trends of sea ice. The sea-ice coupling remarkably enhances the predictive capability for the Arctic 2-m temperature, indicating the importance of this factor, particularly for seasonal predictions in the Arctic region.

  10. MRI in ocular drug delivery

    OpenAIRE

    Li, S. Kevin; Lizak, Martin J.; Jeong, Eun-Kee

    2008-01-01

    Conventional pharmacokinetic methods for studying ocular drug delivery are invasive and cannot be conveniently applied to humans. The advancement of MRI technology has provided new opportunities in ocular drug-delivery research. MRI provides a means to non-invasively and continuously monitor ocular drug-delivery systems with a contrast agent or compound labeled with a contrast agent. It is a useful technique in pharmacokinetic studies, evaluation of drug-delivery methods, and drug-delivery de...

  11. The Science of String Instruments

    CERN Document Server

    Rossing, Thomas D

    2010-01-01

    Many performing musicians, as well as instrument builders, are coming to realize the importance of understanding the science of musical instruments. This book explains how string instruments produce sound. It presents basic ideas in simple language, and it also translates some more sophisticated ideas in non-technical language. It should be of interest to performers, researchers, and instrument makers alike.

  12. Instrumentation for Nuclear Applications

    International Nuclear Information System (INIS)

    1998-01-01

    The objective of this project was to develop and coordinate nuclear instrumentation standards with resulting economies for the nuclear and radiation fields. There was particular emphasis on coordination and management of the Nuclear Instrument Module (NIM) System, U.S. activity involving the CAMAC international standard dataway system, the FASTBUS modular high-speed data acquisition and control system and processing and management of national nuclear instrumentation and detector standards, as well as a modest amount of assistance and consultation services to the Pollutant Characterization and Safety Research Division of the Office of Health and Environmental Research. The principal accomplishments were the development and maintenance of the NIM instrumentation system that is the predominant instrumentation system in the nuclear and radiation fields worldwide, the CAMAC digital interface system in coordination with the ESONE Committee of European Laboratories, the FASTBUS high-speed system and numerous national and international nuclear instrumentation standards

  13. A low-cost MRI compatible keyboard

    DEFF Research Database (Denmark)

    Jensen, Martin Snejbjerg; Heggli, Ole Adrian; Alves da Mota, Patricia

    2017-01-01

    , presenting a challenging environment for playing an instrument. Here, we present an MRI-compatible polyphonic keyboard with a materials cost of 850 $, designed and tested for safe use in 3T (three Tesla) MRI-scanners. We describe design considerations, and prior work in the field. In addition, we provide...... recommendations for future designs and comment on the possibility of using the keyboard in magnetoencephalography (MEG) systems. Preliminary results indicate a comfortable playing experience with no disturbance of the imaging process....

  14. MRI-powered biomedical devices.

    Science.gov (United States)

    Hovet, Sierra; Ren, Hongliang; Xu, Sheng; Wood, Bradford; Tokuda, Junichi; Tse, Zion Tsz Ho

    2017-11-16

    Magnetic resonance imaging (MRI) is beneficial for imaging-guided procedures because it provides higher resolution images and better soft tissue contrast than computed tomography (CT), ultrasound, and X-ray. MRI can be used to streamline diagnostics and treatment because it does not require patients to be repositioned between scans of different areas of the body. It is even possible to use MRI to visualize, power, and control medical devices inside the human body to access remote locations and perform minimally invasive procedures. Therefore, MR conditional medical devices have the potential to improve a wide variety of medical procedures; this potential is explored in terms of practical considerations pertaining to clinical applications and the MRI environment. Recent advancements in this field are introduced with a review of clinically relevant research in the areas of interventional tools, endovascular microbots, and closed-loop controlled MRI robots. Challenges related to technology and clinical feasibility are discussed, including MRI based propulsion and control, navigation of medical devices through the human body, clinical adoptability, and regulatory issues. The development of MRI-powered medical devices is an emerging field, but the potential clinical impact of these devices is promising.

  15. PET/MRI for Neurological Applications

    Science.gov (United States)

    Catana, Ciprian; Drzezga, Alexander; Heiss, Wolf-Dieter; Rosen, Bruce R.

    2013-01-01

    PET and MRI provide complementary information in the study of the human brain. Simultaneous PET/MR data acquisition allows the spatial and temporal correlation of the measured signals, opening up opportunities impossible to realize using stand-alone instruments. This paper reviews the methodological improvements and potential neurological and psychiatric applications of this novel technology. We first present methods for improving the performance and information content of each modality by using the information provided by the other technique. On the PET side, we discuss methods that use the simultaneously acquired MR data to improve the PET data quantification. On the MR side, we present how improved PET quantification could be used to validate a number of MR techniques. Finally, we describe promising research, translational and clinical applications that could benefit from these advanced tools. PMID:23143086

  16. Nuclear medicine and imaging research. Instrumentation and quantitative methods of evaluation. Progress report, January 15, 1984-January 14, 1985

    International Nuclear Information System (INIS)

    Beck, R.N.; Cooper, M.D.

    1984-09-01

    This program addresses problems involving the basic science and technology of radioactive tracer methods as they relate to nuclear medicine and imaging. The broad goal is to develop new instruments and methods for image formation, processing, quantitation and display, so as to maximize the diagnostic information per unit of absorbed radiation dose to the patient. Project I addresses problems associated with the quantitative imaging of single-photon emitters; Project II addresses similar problems associated with the quantitative imaging of positron emitters; Project III addresses methodological problems associated with the quantitative evaluation of the efficacy of diagnostic imaging procedures

  17. Repair, Evaluation, Maintenance, and Rehabilitation Research Program. Instrumentation Automation for Concrete Structures. Report 2. Automation Hardware and Retrofitting Techniques.

    Science.gov (United States)

    1987-06-01

    characteristics unaffected le by condensation of water on the sensor surface. Aggressive pollutants in the air have little effect on the performance. However...THERMOCOUPLE (PHOTO COURTESY OF FOXBORO CO. ) Sb. Manufacturer: Burling Instrument Company % P.O. Box 298, 16 River Rd. & A"’ Chatham, NJ 07928 -’,1[.w...EA YSE NTALTO re’ lot. I 4 -4 V V V .* o ’~% 1 ... .... REM-R U ....... R..R. RIMAC RR TELEETR , CMPTER L FIGURE 45. REMAC SYSTEM CONFIGURATION AL

  18. MRI of the Chest

    Medline Plus

    Full Text Available ... affecting the MRI images, these objects can become projectiles within the MRI scanner room and may cause ... MRI has proven valuable in diagnosing a broad range of conditions, including cancer, heart and vascular disease, ...

  19. MRI of the Chest

    Medline Plus

    Full Text Available ... or patients with claustrophobia. Other MRI machines are open on the sides (open MRI). Open units are especially helpful for examining larger patients or those with claustrophobia. Newer open MRI units provide very high quality images for ...

  20. MRI (Magnetic Resonance Imaging)

    Science.gov (United States)

    ... Procedures Medical Imaging MRI (Magnetic Resonance Imaging) MRI (Magnetic Resonance Imaging) Share Tweet Linkedin Pin it More sharing options Linkedin Pin it Email Print Magnetic Resonance Imaging (MRI) is a medical imaging procedure for ...

  1. MRI of the Chest

    Medline Plus

    Full Text Available ... does not completely surround you. Some newer MRI machines have a larger diameter bore which can be ... size patients or patients with claustrophobia. Other MRI machines are open on the sides (open MRI). Open ...

  2. MRI of the Chest

    Medline Plus

    Full Text Available ... in the first three to four months of pregnancy unless the potential benefit from the MRI exam ... the MRI Safety page for more information about pregnancy and MRI. If you have claustrophobia (fear of ...

  3. MRI of the Chest

    Medline Plus

    Full Text Available ... News Physician Resources Professions Site Index A-Z Magnetic Resonance Imaging (MRI) - Chest Magnetic resonance imaging (MRI) ... clearer and more detailed than with other imaging methods. This detail makes MRI an invaluable tool in ...

  4. Play the MRI Game

    Science.gov (United States)

    ... Teachers' Questionnaire MRI Play MRI the Magnetic Miracle Game About the game In the MRI imaging technique, strong magnets and ... last will in Paris. Play the Blood Typing Game Try to save some patients and learn about ...

  5. Development of a Survey Instrument to Measure TEFL Academics' Perceptions about, Individual and Workplace Characteristics for Conducting Research

    Science.gov (United States)

    Bai, Li; Hudson, Peter; Millwater, Jan; Tones, Megan

    2013-01-01

    A 30-item survey was devised to determine Chinese TEFL (Teaching English as a Foreign Language) academics' potential for conducting research. A five-part Likert scale was used to gather data from 182 academics on four factors: (1) perceptions on teaching-research nexus, (2) personal perspectives for conducting research, (3) predispositions for…

  6. The Flare Irradiance Spectral Model (FISM) and its Contributions to Space Weather Research, the Flare Energy Budget, and Instrument Design

    Science.gov (United States)

    Chamberlin, Phillip

    2008-01-01

    The Flare Irradiance Spectral Model (FISM) is an empirical model of the solar irradiance spectrum from 0.1 to 190 nm at 1 nm spectral resolution and on a 1-minute time cadence. The goal of FISM is to provide accurate solar spectral irradiances over the vacuum ultraviolet (VUV: 0-200 nm) range as input for ionospheric and thermospheric models. The seminar will begin with a brief overview of the FISM model, and also how the Solar Dynamics Observatory (SDO) EUV Variability Experiment (EVE) will contribute to improving FISM. Some current studies will then be presented that use FISM estimations of the solar VUV irradiance to quantify the contributions of the increased irradiance from flares to Earth's increased thermospheric and ionospheric densites. Initial results will also be presented from a study looking at the electron density increases in the Martian atmosphere during a solar flare. Results will also be shown quantifying the VUV contributions to the total flare energy budget for both the impulsive and gradual phases of solar flares. Lastly, an example of how FISM can be used to simplify the design of future solar VUV irradiance instruments will be discussed, using the future NOAA GOES-R Extreme Ultraviolet and X-Ray Sensors (EXIS) space weather instrument.

  7. Animal MRI Core

    Data.gov (United States)

    Federal Laboratory Consortium — The Animal Magnetic Resonance Imaging (MRI) Core develops and optimizes MRI methods for cardiovascular imaging of mice and rats. The Core provides imaging expertise,...

  8. Accuracy Verification of Magnetic Resonance Imaging (MRI) Technology for Lower-Limb Prosthetic Research: Utilising Animal Soft Tissue Specimen and Common Socket Casting Materials

    OpenAIRE

    Safari, Mohammad Reza; Rowe, Philip; Buis, Arjan

    2012-01-01

    Lower limb prosthetic socket shape and volume consistency can be quantified using MRI technology. Additionally, MRI images of the residual limb could be used as an input data for CAD-CAM technology and finite element studies. However, the accuracy of MRI when socket casting materials are used has to be defined. A number of six, 46 mm thick, cross-sections of an animal leg were used. Three specimens were wrapped with Plaster of Paris (POP) and the other three with commercially available silico...

  9. Research on the evaluation model of the software reliability in nuclear safety class digital instrumentation and control system

    International Nuclear Information System (INIS)

    Liu Ying; Yang Ming; Li Fengjun; Ma Zhanguo; Zeng Hai

    2014-01-01

    In order to analyze the software reliability (SR) in nuclear safety class digital instrumentation and control system (D-I and C), firstly, the international software design standards were analyzed, the standards' framework was built, and we found that the D-I and C software standards should follow the NUREG-0800 BTP7-14, according to the NRC NUREG-0800 review of requirements. Secondly, the quantitative evaluation model of SR using Bayesian Belief Network and thirteen sub-model frameworks were established. Thirdly, each sub-models and the weight of corresponding indexes in the evaluation model were analyzed. Finally, the safety case was introduced. The models lay a foundation for review and quantitative evaluation on the SR in nuclear safety class D-I and C. (authors)

  10. Research and development in the field of nuclear power plant control and instrumentation in Japan during 1987-1988

    International Nuclear Information System (INIS)

    Wakayama, N.

    1990-01-01

    This paper was provided for the 12th IAEA/IWG-NPPCI Meeting and aims to introduce an outline of recent R and D activities in Japan in the field of Nuclear Power Plant Control and Instrumentation. In the area of sensors, equipment and systems, various kinds of micro-processor based digital instrumentation and control components/systems have been developed for the distributed C and I systems for the Advanced LWR Plants under planning. Remarkable progress has been also obtained in the development of advanced sensors such as a Four Section Ex-core Neutron Chamber for PWR, some kinds of High-Temperature (600 - 800 deg. C) and Wide Range Neutron Counter Chambers for HTGR, and High-Temperature (1200 deg. C)/High-stability In-Core Thermocouples. Method of verification and validation of the micro-processor based protection and safety systems was studied and a proving test of the systems has been undertaken to use the systems for the Advanced LWR plants. Extensive studies have also been made in the field of Human Factors, Man-Machine Interface and Operator Support System. Operators' behaviour, performance and cognitive process were investigated and cognitive model and crew performance model have been provided for the advanced MMI design and evaluation. Development programme of the Advanced Man-Machine System was continued for the further improvement of the MMI of NPPs. The AI technology has been introduced widely into the operator support systems, and the performance and flexibility of the systems have been improved remarkably. As for the training equipment, high-performance on-site compact simulators have been developed and installed in plant sites. Various kinds of maintenance support systems have been also developed by the united efforts of utilities and manufacturers. A list of 131 references is provided in this paper for the convenience of readers. (author). 131 refs, 1 tab

  11. Instrumentation Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Provides instrumentation support for flight tests of prototype weapons systems using a vast array of airborne sensors, transducers, signal conditioning and encoding...

  12. Variability among Research Diagnostic Interview Instruments in the Application of "DSM-IV-TR" Criteria for Pediatric Bipolar Disorder

    Science.gov (United States)

    Galanter, Cathryn A.; Hundt, Stephanie R.; Goyal, Parag; Le, Jenna; Fisher, Prudence W.

    2012-01-01

    Objective: The "DSM-IV-TR "criteria for a manic episode and bipolar disorder (BD) were developed for adults but are used for children. The manner in which clinicians and researchers interpret these criteria may have contributed to the increase in BD diagnoses given to youth. Research interviews are designed to improve diagnostic reliability and…

  13. Parsimonious and efficient assessment of health-related quality of life in osteoarthritis research: validation of the Assessment of Quality of Life (AQoL instrument

    Directory of Open Access Journals (Sweden)

    Segal Leonie

    2006-03-01

    Full Text Available Abstract Background The Assessment of Quality of Life (AQoL utility instrument was psychometrically developed for the general population. This study aimed to explore its potential as an osteoarthritis (OA outcome measure. Methods WOMAC, Lequesne index, SF-36, Visual analogue scales and the AQoL were administered to 222 people with OA. The ability of each questionnaire to detect differences between groups was based on (i self-rated health (SRH and, (ii differences between people on an orthopedic waiting list (WL vs people with OA in the community (C. Comparisons included effect size, relative efficiency and receiver operator characteristic curves. Results All instruments detected differences between groups; however no one instrument exhibited superior efficiency. The AQoL demonstrated strong psychometric properties. Conclusion The AQoL has equivalent performance to comparator questionnaires commonly used in OA research and would be a useful adjunct to well-established disease specific scales. The AQoL has important advantages; brevity (12 items, facilitates comparisons between disease groups, and delivers a utility score that can be used in health economic evaluations.

  14. Nuclear medicine and image research: instrumentation and quantitative methods of evaluation. Comprehensive 3-year progress report, January 15, 1983-January 14, 1986

    International Nuclear Information System (INIS)

    Beck, R.N.; Cooper, M.D.

    1985-09-01

    This program of research addresses problems involving the basic science and technology of radioactive tracer methods as they relate to nuclear medicine and imaging. The broad goal is to develop new instruments and methods for image formation, processing, quantitation, and display, so as to maximize the diagnostic information per unit of absorbed radiation dose to the patient. Project I addresses problems with the quantitative imaging a single-photon emitters; Project II addresses similar problems associated with the quantitative imaging of positron emitters; Project III addresses methodological problems associated with the quantitative evaluation of the efficacy of diagnostic imaging procedures

  15. MRI-Only Based Radiotherapy Treatment Planning for the Rat Brain on a Small Animal Radiation Research Platform (SARRP.

    Directory of Open Access Journals (Sweden)

    Shandra Gutierrez

    Full Text Available Computed tomography (CT is the standard imaging modality in radiation therapy treatment planning (RTP. However, magnetic resonance (MR imaging provides superior soft tissue contrast, increasing the precision of target volume selection. We present MR-only based RTP for a rat brain on a small animal radiation research platform (SARRP using probabilistic voxel classification with multiple MR sequences. Six rat heads were imaged, each with one CT and five MR sequences. The MR sequences were: T1-weighted, T2-weighted, zero-echo time (ZTE, and two ultra-short echo time sequences with 20 μs (UTE1 and 2 ms (UTE2 echo times. CT data were manually segmented into air, soft tissue, and bone to obtain the RTP reference. Bias field corrected MR images were automatically segmented into the same tissue classes using a fuzzy c-means segmentation algorithm with multiple images as input. Similarities between segmented CT and automatic segmented MR (ASMR images were evaluated using Dice coefficient. Three ASMR images with high similarity index were used for further RTP. Three beam arrangements were investigated. Dose distributions were compared by analysing dose volume histograms. The highest Dice coefficients were obtained for the ZTE-UTE2 combination and for the T1-UTE1-T2 combination when ZTE was unavailable. Both combinations, along with UTE1-UTE2, often used to generate ASMR images, were used for further RTP. Using 1 beam, MR based RTP underestimated the dose to be delivered to the target (range: 1.4%-7.6%. When more complex beam configurations were used, the calculated dose using the ZTE-UTE2 combination was the most accurate, with 0.7% deviation from CT, compared to 0.8% for T1-UTE1-T2 and 1.7% for UTE1-UTE2. The presented MR-only based workflow for RTP on a SARRP enables both accurate organ delineation and dose calculations using multiple MR sequences. This method can be useful in longitudinal studies where CT's cumulative radiation dose might contribute

  16. MRI-Only Based Radiotherapy Treatment Planning for the Rat Brain on a Small Animal Radiation Research Platform (SARRP).

    Science.gov (United States)

    Gutierrez, Shandra; Descamps, Benedicte; Vanhove, Christian

    2015-01-01

    Computed tomography (CT) is the standard imaging modality in radiation therapy treatment planning (RTP). However, magnetic resonance (MR) imaging provides superior soft tissue contrast, increasing the precision of target volume selection. We present MR-only based RTP for a rat brain on a small animal radiation research platform (SARRP) using probabilistic voxel classification with multiple MR sequences. Six rat heads were imaged, each with one CT and five MR sequences. The MR sequences were: T1-weighted, T2-weighted, zero-echo time (ZTE), and two ultra-short echo time sequences with 20 μs (UTE1) and 2 ms (UTE2) echo times. CT data were manually segmented into air, soft tissue, and bone to obtain the RTP reference. Bias field corrected MR images were automatically segmented into the same tissue classes using a fuzzy c-means segmentation algorithm with multiple images as input. Similarities between segmented CT and automatic segmented MR (ASMR) images were evaluated using Dice coefficient. Three ASMR images with high similarity index were used for further RTP. Three beam arrangements were investigated. Dose distributions were compared by analysing dose volume histograms. The highest Dice coefficients were obtained for the ZTE-UTE2 combination and for the T1-UTE1-T2 combination when ZTE was unavailable. Both combinations, along with UTE1-UTE2, often used to generate ASMR images, were used for further RTP. Using 1 beam, MR based RTP underestimated the dose to be delivered to the target (range: 1.4%-7.6%). When more complex beam configurations were used, the calculated dose using the ZTE-UTE2 combination was the most accurate, with 0.7% deviation from CT, compared to 0.8% for T1-UTE1-T2 and 1.7% for UTE1-UTE2. The presented MR-only based workflow for RTP on a SARRP enables both accurate organ delineation and dose calculations using multiple MR sequences. This method can be useful in longitudinal studies where CT's cumulative radiation dose might contribute to the total

  17. Experimental and Computational Instrumentation for Rotorcraft Noise and Vibration Control Research at the Penn State Rotorcraft Center

    National Research Council Canada - National Science Library

    Smith, Edward

    2001-01-01

    A team of faculty at the Penn State Rotorcraft Center of Excellence has integrated five new facilities into a broad range of research and educational programs focused on rotorcraft noise and vibration control...

  18. Research and Implementation of Software Used for the Remote Control for VM700T Video Measuring Instrument

    Directory of Open Access Journals (Sweden)

    Song Wenjie

    2015-01-01

    Full Text Available In this paper, the measurement software which can be used to realize remote control of the VM700T video measuring instrument is introduced. The authors can operate VM700T by a virtual panel on the client computer, select the results that the measuring equipment displayed to transmit it, and then display the image on the VM700T virtual panel in real time. The system does have some practical values and play an important role in distance learning. The functions that the system realized mainly includes four aspects: the real-time transmission of message based on the socket technology, the serial connection between server PC and VM700T measuring equipment, the image acquisition based on VFW technology and JPEG compression and decompression, and the network transmission of image files. The actual network transmission test is shown that the data acquisition method of this thesis is flexible and convenient, and the system is of extraordinary stability. It can display the measurement results in real time and basically realize the requirements of remote control. In the content, this paper includes a summary of principle, the detailed introduction of the system realization process and some related technology.

  19. Instrumentation development

    International Nuclear Information System (INIS)

    Ubbes, W.F.; Yow, J.L. Jr.

    1988-01-01

    Instrumentation is developed for the Civilian Radioactive Waste Management Program to meet several different (and sometimes conflicting) objectives. This paper addresses instrumentation development for data needs that are related either directly or indirectly to a repository site, but does not touch on instrumentation for work with waste forms or other materials. Consequently, this implies a relatively large scale for the measurements, and an in situ setting for instrument performance. In this context, instruments are needed for site characterization to define phenomena, develop models, and obtain parameter values, and for later design and performance confirmation testing in the constructed repository. The former set of applications is more immediate, and is driven by the needs of program design and performance assessment activities. A host of general technical and nontechnical issues have arisen to challenge instrumentation development. Instruments can be classed into geomechanical, geohydrologic, or other specialty categories, but these issues cut across artificial classifications. These issues are outlined. Despite this imposing list of issues, several case histories are cited to evaluate progress in the area

  20. Functional MRI of Language Processing and Recovery

    NARCIS (Netherlands)

    C. Méndez Orellana (Carolina)

    2015-01-01

    markdownabstract__Abstract__ My thesis describe the utility of implementing fMRI to investigate how the language system is reorganized in brain damaged patients. Specifically for aphasia research fMRI allows to show how specific language treatment methods have the potential to enhance language

  1. Accuracy verification of magnetic resonance imaging (MRI) technology for lower-limb prosthetic research: utilising animal soft tissue specimen and common socket casting materials.

    Science.gov (United States)

    Safari, Mohammad Reza; Rowe, Philip; Buis, Arjan

    2012-01-01

    Lower limb prosthetic socket shape and volume consistency can be quantified using MRI technology. Additionally, MRI images of the residual limb could be used as an input data for CAD-CAM technology and finite element studies. However, the accuracy of MRI when socket casting materials are used has to be defined. A number of six, 46 mm thick, cross-sections of an animal leg were used. Three specimens were wrapped with Plaster of Paris (POP) and the other three with commercially available silicone interface liner. Data was obtained by utilising MRI technology and then the segmented images compared to corresponding calliper measurement, photographic imaging, and water suspension techniques. The MRI measurement results were strongly correlated with actual diameter, surface area, and volume measurements. The results show that the selected scanning parameters and the semiautomatic segmentation method are adequate enough, considering the limit of clinical meaningful shape and volume fluctuation, for residual limb volume and the cross-sectional surface area measurements.

  2. Accuracy Verification of Magnetic Resonance Imaging (MRI Technology for Lower-Limb Prosthetic Research: Utilising Animal Soft Tissue Specimen and Common Socket Casting Materials

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Safari

    2012-01-01

    Full Text Available Lower limb prosthetic socket shape and volume consistency can be quantified using MRI technology. Additionally, MRI images of the residual limb could be used as an input data for CAD-CAM technology and finite element studies. However, the accuracy of MRI when socket casting materials are used has to be defined. A number of six, 46 mm thick, cross-sections of an animal leg were used. Three specimens were wrapped with Plaster of Paris (POP and the other three with commercially available silicone interface liner. Data was obtained by utilising MRI technology and then the segmented images compared to corresponding calliper measurement, photographic imaging, and water suspension techniques. The MRI measurement results were strongly correlated with actual diameter, surface area, and volume measurements. The results show that the selected scanning parameters and the semiautomatic segmentation method are adequate enough, considering the limit of clinical meaningful shape and volume fluctuation, for residual limb volume and the cross-sectional surface area measurements.

  3. Computational Diffusion MRI : MICCAI Workshop

    CERN Document Server

    Grussu, Francesco; Ning, Lipeng; Tax, Chantal; Veraart, Jelle

    2018-01-01

    This volume presents the latest developments in the highly active and rapidly growing field of diffusion MRI. The reader will find numerous contributions covering a broad range of topics, from the mathematical foundations of the diffusion process and signal generation, to new computational methods and estimation techniques for the in-vivo recovery of microstructural and connectivity features, as well as frontline applications in neuroscience research and clinical practice. These proceedings contain the papers presented at the 2017 MICCAI Workshop on Computational Diffusion MRI (CDMRI’17) held in Québec, Canada on September 10, 2017, sharing new perspectives on the most recent research challenges for those currently working in the field, but also offering a valuable starting point for anyone interested in learning computational techniques in diffusion MRI. This book includes rigorous mathematical derivations, a large number of rich, full-colour visualisations and clinically relevant results. As such, it wil...

  4. The Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders: recruitment, assessment instruments, methods for the development of multicenter collaborative studies and preliminary results.

    Science.gov (United States)

    Miguel, Euripedes Constantino; Ferrão, Ygor Arzeno; Rosário, Maria Conceição do; Mathis, Maria Alice de; Torres, Albina Rodrigues; Fontenelle, Leonardo Franklin; Hounie, Ana Gabriela; Shavitt, Roseli Gedanke; Cordioli, Aristides Volpato; Gonzalez, Christina Hojaij; Petribú, Kátia; Diniz, Juliana Belo; Malavazzi, Dante Marino; Torresan, Ricardo C; Raffin, Andréa Litvin; Meyer, Elisabeth; Braga, Daniela T; Borcato, Sonia; Valério, Carolina; Gropo, Luciana N; Prado, Helena da Silva; Perin, Eduardo Alliende; Santos, Sandro Iêgo; Copque, Helen; Borges, Manuela Corrêa; Lopes, Angélica Prazeres; Silva, Elenita D da

    2008-09-01

    To describe the recruitment of patients, assessment instruments, implementation, methods and preliminary results of The Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders, which includes seven university sites. This cross-sectional study included a comprehensive clinical assessment including semi-structured interviews (sociodemographic data, medical and psychiatric history, disease course and comorbid psychiatric diagnoses), and instruments to assess obsessive-compulsive (Yale-Brown Obsessive-Compulsive Scale and Dimensional Yale-Brown Obsessive-Compulsive Scale), depressive (Beck Depression Inventory) and anxious (Beck Anxiety Inventory) symptoms, sensory phenomena (Universidade de São Paulo Sensory Phenomena Scale), insight (Brown Assessment Beliefs Scale), tics (Yale Global Tics Severity Scale) and quality of life (Medical Outcome Quality of Life Scale Short-form-36 and Social Assessment Scale). The raters' training consisted of watching at least five videotaped interviews and interviewing five patients with an expert researcher before interviewing patients alone. The reliability between all leaders for the most important instruments (Structured Clinical Interview for DSM-IV, Dimensional Yale-Brown Obsessive-Compulsive Scale, Universidade de São Paulo Sensory Phenomena Scale) was measured after six complete interviews. Inter-rater reliability was 96%. By March 2008, 630 obsessive-compulsive disorder patients had been systematically evaluated. Mean age (+/-SE) was 34.7 (+/-0.51), 56.3% were female, and 84.6% Caucasian. The most prevalent obsessive compulsive symptom dimensions were symmetry and contamination. The most common comorbidities were major depression, generalized anxiety and social anxiety disorder. The most common DSM-IV impulsive control disorder was skin picking. The sample was composed mainly by Caucasian individuals, unmarried, with some kind of occupational activity, mean age of 35 years, onset of obsessive

  5. The Texts of the Instruments Concerning the Agency's Assistance to Indonesia for the Continuation of a Research Reactor Project

    International Nuclear Information System (INIS)

    1970-01-01

    The texts of the Supply Agreement between the Agency and the Governments of Indonesia and the United States of America, and of the Project Agreement between the Agency and the Government of Indonesia concerning the Agency's assistance to that Government for the continuation of a research reactor project, are reproduced in this document for the information of all Members. Both Agreements entered into force on 19 December 1969.

  6. The Texts of the Instruments connected with the Agency's Assistance to Finland in Establishing a Research Reactor Project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1961-01-24

    The texts of the Supply Agreement between the Agency, the Government of Finland and the Government of the United States of America, and of the Project Agreement between the Agency and the Government of Finland, in connection with the Agency's assistance to the Government of Finland in establishing a research reactor project, are reproduced in this document for the information of all Members of the Agency. These agreements entered into force on 30 December 1960.

  7. The Texts of the Instruments connected with the Agency's Assistance to Pakistan in Establishing a Research Reactor Project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1962-03-22

    The texts of the Supply Agreement between the Agency, the Government of Pakistan and the Government of the United States of America, and of the Project Agreement between the Agency and the Government of Pakistan, in connection with the Agency's assistance to the Government of Pakistan-in establishing a research reactor project, are reproduced in this document for the information of all Members of the Agency. These Agreements entered into force on 5 March 1962.

  8. The Texts of the Instruments connected with the Agency's Assistance to Yugoslavia in Establishing a Research Reactor Project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1961-11-24

    The texts of the Supply Agreement between the Agency, the Government of Yugoslavia and the Government of the United States of America, and of the Project Agreement between the Agency and the Government of Yugoslavia, in connection with the Agency's assistance to the Government of Yugoslavia in establishing a research reactor project, are reproduced in this document for the information of all Members of the Agency. These Agreements entered into force on 4 October 1961.

  9. The Texts of the Instruments Concerning the Agency's Assistance to Indonesia for the Continuation of a Research Reactor Project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1970-02-08

    The texts of the Supply Agreement between the Agency and the Governments of Indonesia and the United States of America, and of the Project Agreement between the Agency and the Government of Indonesia concerning the Agency's assistance to that Government for the continuation of a research reactor project, are reproduced in this document for the information of all Members. Both Agreements entered into force on 19 December 1969.

  10. The Texts of the Instruments connected with the Agency's Assistance to Mexico in Establishing a Research Reactor Project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1964-01-30

    The texts of the Supply Agreement between the Agency and the Governments of Mexico and the United States of America, and of the Project Agreement between the Agency and the Government of Mexico, in connection with the Agency's assistance to that Government in establishing a research reactor project, are reproduced in this document for the information of all Members. These Agreements entered into force on 18 December 1963.

  11. The Texts of the Instruments connected with the Agency's Assistance to Iran in Establishing a Research Reactor Project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1967-08-31

    The texts of the Supply Agreement between the Agency and the Governments of Iran and the United States of America, and of the Project Agreement between the Agency and the Government of Iran, connected with the Agency's assistance to the latter Government in establishing a research reactor project, are reproduced in this document for the information of all Members. The Agreements entered into force on 7 June and 10 May 1967 respectively.

  12. The Texts of the Instruments Concerning the Agency's Assistance to Chile for the Establishment of a Research Reactor Project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1970-02-09

    The texts of the Supply Agreement between the Agency and the Governments of Chile and the United States of America, and of the Project Agreement between the Agency and the Government of Chile concerning the Agency's assistance to that Government for the establishment of a research reactor project, are reproduced in this document for the information of all Members. Both Agreements entered into force on 19 December 1969.

  13. The Texts of the Instruments Concerning the Agency's Assistance to Venezuela for the Continuation of a Research Reactor Project

    International Nuclear Information System (INIS)

    1976-01-01

    The texts of the Title Transfer Agreement between the Agency and the Governments of the United States of America and Venezuela, and of the Project Agreement between the Agency and the Government of Venezuela concerning the Agency's assistance to that Government for the continuation of a research reactor project, are reproduced herein for the information of all Members. Both Agreements entered into force on 7 November 1975, pursuant to Articles IV and X respectively.

  14. The Texts of the Instruments Concerning the Agency's Assistance to Chile for the Establishment of a Research Reactor Project

    International Nuclear Information System (INIS)

    1970-01-01

    The texts of the Supply Agreement between the Agency and the Governments of Chile and the United States of America, and of the Project Agreement between the Agency and the Government of Chile concerning the Agency's assistance to that Government for the establishment of a research reactor project, are reproduced in this document for the information of all Members. Both Agreements entered into force on 19 December 1969.

  15. The Texts of the Instruments connected with the Agency's assistance to Uruguay in Establishing a Research Reactor Project

    International Nuclear Information System (INIS)

    1965-01-01

    The texts of the Supply Agreement between the Agency and the Governments of the United States of America and Uruguay, and of the Project Agreement between the Agency and the Government of Uruguay, in connection with the Agency's assistance to the latter Government in establishing a research reactor project, are reproduced in this document for the information of all Members. These Agreements entered into force on 24 September 1965

  16. The texts of the instruments concerning the Agency's assistance to Romania for the establishment of a research reactor project

    International Nuclear Information System (INIS)

    1991-11-01

    As a sequel to the assistance which the Agency has provided to the Government of Romania in connection with a research reactor project (IAEA-INFCIRC/206, 206 Adds.1 and 2 and Mod.2), the Agency and the Governments of Romania and the United States of America, on 14 June 1991, concluded a Fourth Supply Agreement. The text of that Agreement, which was approved by the Board of Governors on 14 June 1991, is reproduced in this document

  17. The texts of the instruments concerning the Agency's assistance to Romania for the establishment of a research reactor project

    International Nuclear Information System (INIS)

    1991-08-01

    On June 15, 1990, the Agency and the Government of Romania signed a letter constituting an agreement amending the Project Agreement (IAEA-INFCIRC/206, Part II) concluded in connection with the Agency's assistance to Romania for the establishment of a research reactor project. The text of that letter, which was approved by the Board of Governors on June 15, 1990, is reproduced in this document. 1 tab

  18. Comparison of the Safety Critical Software V and V Requirements for the Research Reactor Instrumentation and Control System

    Energy Technology Data Exchange (ETDEWEB)

    Joo, Sungmoon; Suh, Yong-Suk; Park, Cheol [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    This study was motivated by a research reactor project where the owner of the project and the equipment vendors are from two different standards frameworks. This paper reviews two major standards frameworks - NRC-IEEE and IAEA-IEC - and the software classification schemes as a background, then discuss the V and V issue. The purpose of this paper is by no means to solve the cross-standards-framework qualification issue, but, rather, is to remind the stakeholders of research reactor projects. V and V are also essential for the approval from regulatory bodies. As standards define or recommend consolidated engineering practices, methods, or criteria, V and V activities for software qualification are not exceptional. Within a standards framework, usually, the processes for the qualification of safety-critical software are well-established such that the safety is maximized while minimizing the compromises in software quality, safety, and reliability. When, however, multiple standards frameworks are involved in a research reactor project, it is difficult for equipment vendors to implement appropriate V and V activities as there is no unified view on this cross-standards-framework qualification issue yet. There are two major standards frameworks for safety-critical software development in nuclear industry. Unfortunately different safety classifications for software and thus different requirements for qualification are in place. What makes things worse is that (i) there are ambiguities in the standards and rooms for each stakeholders’ interpretation, and (ii) there is no one-to-one mapping between the associated V and V methods and activities. These may put the stakeholders of research reactor projects in trouble.

  19. Comparison of the Safety Critical Software V and V Requirements for the Research Reactor Instrumentation and Control System

    International Nuclear Information System (INIS)

    Joo, Sungmoon; Suh, Yong-Suk; Park, Cheol

    2016-01-01

    This study was motivated by a research reactor project where the owner of the project and the equipment vendors are from two different standards frameworks. This paper reviews two major standards frameworks - NRC-IEEE and IAEA-IEC - and the software classification schemes as a background, then discuss the V and V issue. The purpose of this paper is by no means to solve the cross-standards-framework qualification issue, but, rather, is to remind the stakeholders of research reactor projects. V and V are also essential for the approval from regulatory bodies. As standards define or recommend consolidated engineering practices, methods, or criteria, V and V activities for software qualification are not exceptional. Within a standards framework, usually, the processes for the qualification of safety-critical software are well-established such that the safety is maximized while minimizing the compromises in software quality, safety, and reliability. When, however, multiple standards frameworks are involved in a research reactor project, it is difficult for equipment vendors to implement appropriate V and V activities as there is no unified view on this cross-standards-framework qualification issue yet. There are two major standards frameworks for safety-critical software development in nuclear industry. Unfortunately different safety classifications for software and thus different requirements for qualification are in place. What makes things worse is that (i) there are ambiguities in the standards and rooms for each stakeholders’ interpretation, and (ii) there is no one-to-one mapping between the associated V and V methods and activities. These may put the stakeholders of research reactor projects in trouble

  20. The Texts of the Instruments connected with the Agency's assistance to Uruguay in Establishing a Research Reactor Project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1965-12-09

    The texts of the Supply Agreement between the Agency and the Governments of the United States of America and Uruguay, and of the Project Agreement between the Agency and the Government of Uruguay, in connection with the Agency's assistance to the latter Government in establishing a research reactor project, are reproduced in this document for the information of all Members. These Agreements entered into force on 24 September 1965.

  1. The Texts of the Instruments concerning the Agency's Assistance to Greece for the continuation of a Research Reactor Project

    International Nuclear Information System (INIS)

    1972-01-01

    The texts of the Title Transfer Agreement between the Agency and the Governments of Greece and the United States of America, and of the Project Agreement between the Agency and the Government of Greece concerning the Agency's assistance to that Government for the continuation of a research reactor project, are reproduced herein for the information of all Members. Both Agreements entered into force on 1 March 1972

  2. The Texts of the Instruments connected with the Agency's Assistance to Pakistan in Establishing a Research Reactor Project

    International Nuclear Information System (INIS)

    1962-01-01

    The texts of the Supply Agreement between the Agency, the Government of Pakistan and the Government of the United States of America, and of the Project Agreement between the Agency and the Government of Pakistan, in connection with the Agency's assistance to the Government of Pakistan-in establishing a research reactor project, are reproduced in this document for the information of all Members of the Agency. These Agreements entered into force on 5 March 1962

  3. The Texts of the Instruments connected with the Agency's Assistance to Finland in Establishing a Research Reactor Project

    International Nuclear Information System (INIS)

    1961-01-01

    The texts of the Supply Agreement between the Agency, the Government of Finland and the Government of the United States of America, and of the Project Agreement between the Agency and the Government of Finland, in connection with the Agency's assistance to the Government of Finland in establishing a research reactor project, are reproduced in this document for the information of all Members of the Agency. These agreements entered into force on 30 December 1960

  4. The Texts of the Instruments connected with the Agency's Assistance to Iran in Establishing a Research Reactor Project

    International Nuclear Information System (INIS)

    1967-01-01

    The texts of the Supply Agreement between the Agency and the Governments of Iran and the United States of America, and of the Project Agreement between the Agency and the Government of Iran, connected with the Agency's assistance to the latter Government in establishing a research reactor project, are reproduced in this document for the information of all Members. The Agreements entered into force on 7 June and 10 May 1967 respectively

  5. The Texts of the Instruments connected with the Agency's Assistance to Yugoslavia in Establishing a Research Reactor Project

    International Nuclear Information System (INIS)

    1961-01-01

    The texts of the Supply Agreement between the Agency, the Government of Yugoslavia and the Government of the United States of America, and of the Project Agreement between the Agency and the Government of Yugoslavia, in connection with the Agency's assistance to the Government of Yugoslavia in establishing a research reactor project, are reproduced in this document for the information of all Members of the Agency. These Agreements entered into force on 4 October 1961

  6. The Texts of the Instruments connected with the Agency's Assistance to Mexico in Establishing a Research Reactor Project

    International Nuclear Information System (INIS)

    1964-01-01

    The texts of the Supply Agreement between the Agency and the Governments of Mexico and the United States of America, and of the Project Agreement between the Agency and the Government of Mexico, in connection with the Agency's assistance to that Government in establishing a research reactor project, are reproduced in this document for the information of all Members. These Agreements entered into force on 18 December 1963

  7. Instrumental analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seung Jae; Seo, Seong Gyu

    1995-03-15

    This textbook deals with instrumental analysis, which consists of nine chapters. It has Introduction of analysis chemistry, the process of analysis and types and form of the analysis, Electrochemistry on basic theory, potentiometry and conductometry, electromagnetic radiant rays and optical components on introduction and application, Ultraviolet rays and Visible spectrophotometry, Atomic absorption spectrophotometry on introduction, flame emission spectrometry and plasma emission spectrometry. The others like infrared spectrophotometry, X-rays spectrophotometry and mass spectrometry, chromatography and the other instrumental analysis like radiochemistry.

  8. Instrumental analysis

    International Nuclear Information System (INIS)

    Kim, Seung Jae; Seo, Seong Gyu

    1995-03-01

    This textbook deals with instrumental analysis, which consists of nine chapters. It has Introduction of analysis chemistry, the process of analysis and types and form of the analysis, Electrochemistry on basic theory, potentiometry and conductometry, electromagnetic radiant rays and optical components on introduction and application, Ultraviolet rays and Visible spectrophotometry, Atomic absorption spectrophotometry on introduction, flame emission spectrometry and plasma emission spectrometry. The others like infrared spectrophotometry, X-rays spectrophotometry and mass spectrometry, chromatography and the other instrumental analysis like radiochemistry.

  9. LOFT instrumentation

    International Nuclear Information System (INIS)

    Bixby, W.W.

    1979-01-01

    A description of instrumentation used in the Loss-of-Fluid Test (LOFT) large break Loss-of-Coolant Experiments is presented. Emphasis is placed on hydraulic and thermal measurements in the primary system piping and components, reactor vessel, and pressure suppression system. In addition, instrumentation which is being considered for measurement of phenomena during future small break testing is discussed. (orig.) 891 HP/orig. 892 BRE [de

  10. Quality aspects of research reactor operations for instrumental neutron activation analysis. Report of an advisory group meeting

    International Nuclear Information System (INIS)

    2001-05-01

    This publication is intended to provide guidance on quality aspects of research reactor utilization with emphasis on neutron activation analysis (NAA). It is written to provide users with the practical information required to improve their work and to help reactor staff understand the quality assurance requirements that users need from their facilities. While the report is intended to take into account the situation of research reactors in Africa, it should also be of value to other facilities. This publication is applicable to the establishment and implementation of quality aspects at various stages of the utilization of research reactors with emphasis on NAA. It is not intended to be complete and it should be considered as a stepping stone for improvement. It includes references to other documentation that is readily available. This TECDOC provides guidelines for practical quality assurance in the areas of reactor operations and facilities, preparation for irradiations, the irradiation process and conduct of analyses. It also covers areas of general consideration in quality management and includes recommendations for monitoring, registration, correction and prevention for the effective implementation of the programme. It is expected that the guidelines in this report will also be useful in establishing effective cooperation between reactor operators and experimenters for improved and more reliable utilization

  11. Marine toxic substances and pollutants data from sediment corer and other instruments from NOAA Ship RESEARCHER and other platforms in the Caribbean Sea from 1980-07-16 to 1987-11-29 (NODC Accession 8800013)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Marine toxic substance and pollutants data were collected using sediment corer and other instruments in the Caribbean Sea from NOAA Ship RESEARCHER and other...

  12. Temperature profile and other data collected using BT, XBT, and other instruments from NOAA Ship RESEARCHER and other platforms in the Gulf of Mexico from 1982-08-18 to 1985-04-06 (NODC Accession 8900211)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile and other data were collected using XBT, BT, and other instruments from NOAA Ship RESEARCHER and other platforms in the Gulf of Mexico from 18...

  13. Instrumentation for environmental monitoring: biomedical

    International Nuclear Information System (INIS)

    1979-05-01

    An update is presented to Volume four of the six-volume series devoted to a survey of instruments useful for measurements in biomedicine related to environmental research and monitoring. Results of the survey are given as descriptions of the physical and operating characteristics of available instruments, critical comparisons among instrumentation methods, and recommendations of promising methodology and development of new instrumentation. Methods of detection and analysis of gaseous organic pollutants and metals, including Ni and As are presented. Instrument techniques and notes are included on atomic spectrometry and uv and visible absorption instrumentation

  14. The Cup Anemometer, a Fundamental Meteorological Instrument for the Wind Energy Industry. Research at the IDR/UPM Institute

    Science.gov (United States)

    Pindado, Santiago; Cubas, Javier; Sorribes-Palmer, Félix

    2014-01-01

    The results of several research campaigns investigating cup anemometer performance carried out since 2008 at the IDR/UPM Institute are included in the present paper. Several analysis of large series of calibrations were done by studying the effect of the rotor's geometry, climatic conditions during calibration, and anemometers' ageing. More specific testing campaigns were done regarding the cup anemometer rotor aerodynamics, and the anemometer signals. The effect of the rotor's geometry on the cup anemometer transfer function has been investigated experimentally and analytically. The analysis of the anemometer's output signal as a way of monitoring the anemometer status is revealed as a promising procedure for detecting anomalies. PMID:25397921

  15. The texts of the instruments concerning the Agency's assistance to Romania for the establishment of a research reactor project

    International Nuclear Information System (INIS)

    1991-08-01

    As a sequel to the assistance which the Agency has provided to the Government of Romania in connection with a research reactor project (IAEA-INFCIRC/206, IAEA-INFCIRC/206/ Add.1 and IAEA-INFCIRC/206/Mod.2), the Agency, the Government of Romania and the United States of America, on June 15, 1990, signed a letter constituting the Third Supply Agreement. The text of that letter, which was approved by the Board of Governors on June 15, 1990, is reproduced in this document

  16. Instrumentation of x-ray diffraction and materials research on the National Synchrotron Light Source. Final report

    International Nuclear Information System (INIS)

    Liedl, G.L.

    1984-11-01

    MATRIX was organized in 1980 to formulate a research team to design and construct a beam line at NSLS for x-ray diffraction studies of materials. A versatile system was designed to allow a full range of experimental capabilities for wide angle x-ray scattering experiments including surface diffraction studies. The design and construction of the system has been completed. Testing of parts of the system was completed at CHESS and with x-ray sources or other equipment at member institutions. Installation of the beam line at NSLS is in progress and will proceed in parallel with the commissioning of the x-ray ring at NSLS. Full operation of the beam line is expected to be ready by December 1, 1984 being limited only by the source power of NSLS at that time. Useful experiments could be started if the power is at least 2 GeV and 100ma. The MATRIX beam line was one of the first x-ray beam lines to see light in the beam line in early spring of 1984. In July of 1984, the MATRIX beam line as the first port at NSLS to have a monochromatic beam and to scan part of the spectrum from the source. As part of this contract, six publications have resulted from the various projects. Three publications are concerned directly with the beam line and/or its operation while the other three publications are the result of research associated with the project

  17. The Cup Anemometer, a Fundamental Meteorological Instrument for the Wind Energy Industry. Research at the IDR/UPM Institute

    Directory of Open Access Journals (Sweden)

    Santiago Pindado

    2014-11-01

    Full Text Available The results of several research campaigns investigating cup anemometer performance carried out since 2008 at the IDR/UPM Institute are included in the present paper. Several analysis of large series of calibrations were done by studying the effect of the rotor’s geometry, climatic conditions during calibration, and anemometers’ ageing. More specific testing campaigns were done regarding the cup anemometer rotor aerodynamics, and the anemometer signals. The effect of the rotor’s geometry on the cup anemometer transfer function has been investigated experimentally and analytically. The analysis of the anemometer’s output signal as a way of monitoring the anemometer status is revealed as a promising procedure for detecting anomalies.

  18. The texts of the instruments concerning the Agency's assistance to Indonesia for the continuation of a research reactor project

    International Nuclear Information System (INIS)

    1994-08-01

    The text of the amendment to the Project Agreement between the International Atomic Energy Agency and the Government of the Republic of Indonesia for assistance by the Agency to Indonesia in continuing a research reactor project (Part I) and the Fourth Supply Agreement (Part II), which were approved by the Agency's Board of Governors on 4 December 1992 and concluded on 15 January 1993 between the Agency, the Governments of the Republic of Indonesia and the United States of America are reproduced herein for the information of all Members. The amendment to the Project Agreement and the Fourth Supply Agreement entered into force on 15 January 1993, pursuant to Articles VIII and VIII.1 respectively

  19. Competitive advantage of PET/MRI

    Energy Technology Data Exchange (ETDEWEB)

    Jadvar, Hossein, E-mail: jadvar@usc.edu; Colletti, Patrick M.

    2014-01-15

    Multimodality imaging has made great strides in the imaging evaluation of patients with a variety of diseases. Positron emission tomography/computed tomography (PET/CT) is now established as the imaging modality of choice in many clinical conditions, particularly in oncology. While the initial development of combined PET/magnetic resonance imaging (PET/MRI) was in the preclinical arena, hybrid PET/MR scanners are now available for clinical use. PET/MRI combines the unique features of MRI including excellent soft tissue contrast, diffusion-weighted imaging, dynamic contrast-enhanced imaging, fMRI and other specialized sequences as well as MR spectroscopy with the quantitative physiologic information that is provided by PET. Most evidence for the potential clinical utility of PET/MRI is based on studies performed with side-by-side comparison or software-fused MRI and PET images. Data on distinctive utility of hybrid PET/MRI are rapidly emerging. There are potential competitive advantages of PET/MRI over PET/CT. In general, PET/MRI may be preferred over PET/CT where the unique features of MRI provide more robust imaging evaluation in certain clinical settings. The exact role and potential utility of simultaneous data acquisition in specific research and clinical settings will need to be defined. It may be that simultaneous PET/MRI will be best suited for clinical situations that are disease-specific, organ-specific, related to diseases of the children or in those patients undergoing repeated imaging for whom cumulative radiation dose must be kept as low as reasonably achievable. PET/MRI also offers interesting opportunities for use of dual modality probes. Upon clear definition of clinical utility, other important and practical issues related to business operational model, clinical workflow and reimbursement will also be resolved.

  20. Competitive advantage of PET/MRI.

    Science.gov (United States)

    Jadvar, Hossein; Colletti, Patrick M

    2014-01-01

    Multimodality imaging has made great strides in the imaging evaluation of patients with a variety of diseases. Positron emission tomography/computed tomography (PET/CT) is now established as the imaging modality of choice in many clinical conditions, particularly in oncology. While the initial development of combined PET/magnetic resonance imaging (PET/MRI) was in the preclinical arena, hybrid PET/MR scanners are now available for clinical use. PET/MRI combines the unique features of MRI including excellent soft tissue contrast, diffusion-weighted imaging, dynamic contrast-enhanced imaging, fMRI and other specialized sequences as well as MR spectroscopy with the quantitative physiologic information that is provided by PET. Most evidence for the potential clinical utility of PET/MRI is based on studies performed with side-by-side comparison or software-fused MRI and PET images. Data on distinctive utility of hybrid PET/MRI are rapidly emerging. There are potential competitive advantages of PET/MRI over PET/CT. In general, PET/MRI may be preferred over PET/CT where the unique features of MRI provide more robust imaging evaluation in certain clinical settings. The exact role and potential utility of simultaneous data acquisition in specific research and clinical settings will need to be defined. It may be that simultaneous PET/MRI will be best suited for clinical situations that are disease-specific, organ-specific, related to diseases of the children or in those patients undergoing repeated imaging for whom cumulative radiation dose must be kept as low as reasonably achievable. PET/MRI also offers interesting opportunities for use of dual modality probes. Upon clear definition of clinical utility, other important and practical issues related to business operational model, clinical workflow and reimbursement will also be resolved. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  1. Competitive advantage of PET/MRI

    International Nuclear Information System (INIS)

    Jadvar, Hossein; Colletti, Patrick M.

    2014-01-01

    Multimodality imaging has made great strides in the imaging evaluation of patients with a variety of diseases. Positron emission tomography/computed tomography (PET/CT) is now established as the imaging modality of choice in many clinical conditions, particularly in oncology. While the initial development of combined PET/magnetic resonance imaging (PET/MRI) was in the preclinical arena, hybrid PET/MR scanners are now available for clinical use. PET/MRI combines the unique features of MRI including excellent soft tissue contrast, diffusion-weighted imaging, dynamic contrast-enhanced imaging, fMRI and other specialized sequences as well as MR spectroscopy with the quantitative physiologic information that is provided by PET. Most evidence for the potential clinical utility of PET/MRI is based on studies performed with side-by-side comparison or software-fused MRI and PET images. Data on distinctive utility of hybrid PET/MRI are rapidly emerging. There are potential competitive advantages of PET/MRI over PET/CT. In general, PET/MRI may be preferred over PET/CT where the unique features of MRI provide more robust imaging evaluation in certain clinical settings. The exact role and potential utility of simultaneous data acquisition in specific research and clinical settings will need to be defined. It may be that simultaneous PET/MRI will be best suited for clinical situations that are disease-specific, organ-specific, related to diseases of the children or in those patients undergoing repeated imaging for whom cumulative radiation dose must be kept as low as reasonably achievable. PET/MRI also offers interesting opportunities for use of dual modality probes. Upon clear definition of clinical utility, other important and practical issues related to business operational model, clinical workflow and reimbursement will also be resolved

  2. Maintenance of scientific instruments

    International Nuclear Information System (INIS)

    Lucero, E.

    1986-01-01

    During the last years Colombia has increased the use of nuclear techniques, instruments and equipment in ambitious health programs, as well as in research centers, industry and education; this has resulted in numerous maintenance problems. As an alternative solution IAN has established a Central Maintenance Laboratory for nuclear instruments within an International Atomic Energy Agency program for eight Latin American and nine Asian Countries. Established strategies and some results are detailed in this writing

  3. Evaluating the Development of Chemistry Undergraduate Researchers' Scientific Thinking Skills Using Performance-Data: First Findings from the Performance Assessment of Undergraduate Research (PURE) Instrument

    Science.gov (United States)

    Harsh, Joseph; Esteb, John J.; Maltese, Adam V.

    2017-01-01

    National calls in science, technology, engineering, and technology education reform efforts have advanced the wide-scale engagement of students in undergraduate research for the preparation of a workforce and citizenry able to attend to the challenges of the 21st century. Awareness of the potential benefits and costs of these experiences has led…

  4. Proceedings of the Workshop on Risk Perception as Initiator and Steering Instrument of Innovative Research and Development

    International Nuclear Information System (INIS)

    Foskolos, Konstantin; Schmid, Ruth

    1999-03-01

    This Workshop was organised jointly by the Paul Scherrer Institute and the Swiss Federal Institute of Technology (ETH Zurich) in the framework of the SINTER Network, an EU funded Concerted Action within the 4th EU Framework Programme. It was attended by 29 participants from 7 different countries. A prerequisite for ensuring, in the long term, the option of a safe, reliable and competitive nuclear energy supply with the existing competence in Europe, is the merging or networking of ongoing and planned research and development activities, to share tasks and efficiently use the still existing resources. In this context, it is necessary to assess the European and world wide innovation trends in nuclear technology and to bring the opinions regarding their prioritisation down to a common denominator. A key element of this process is the assessment of the social relevance of such innovation trends, i.e. how emerging developments can satisfy real needs of the public and vice versa. This encompasses also questions on the compatibility of nuclear energy with a sustainable development and its corresponding advantages and perspectives. The analysis of earlier developments (technical innovations that emerged as an answer to 'public pressure' both in the domain of nuclear energy and within other technical domains (chemistry, transports, gene technology)) should provide the basis, which would allow such an assessment. Lectures delivered at the workshop on these subjects and accompanying discussions are collected in this volume. (author)

  5. French registry of workers handling engineered nanomaterials as an instrument of integrated system for surveillance and research

    Science.gov (United States)

    Guseva Canu, I.; Boutou-Kempf, O.; Delabre, L.; Ducamp, S.; Iwatsubo, Y.; Marchand, J. L.; Imbernon, E.

    2013-04-01

    Despite the lack of data on the human health potential risks related to the engineered nanomaterials (ENM) exposure, ENM handling spreads in industry. The French government officially charged the InVS to develop an epidemiological surveillance of workers occupationally exposed to ENM. An initial surveillance plan was proposed on the basis of literature review and discussions with national and international ENM and occupational safety and health (OSH) experts. In site investigations and technical visits were then carried out to build an adequate surveillance system and to assess its feasibility. The current plan consists of a multi-step methodology where exposure registry construction is paramount. Workers potentially exposed to carbon nanotubes (CNT) or nanometric titanium dioxide (TiO2) will be identified using a 3-level approach: 1-identification and selection of companies concerned with ENM exposure (based on compulsory declaration and questionnaires), 2-in site exposure assessment and identification of the jobs/tasks with ENM exposure (based on job-expose matrix, further supplemented with measurements), and 3-identification of workers concerned. Data of interest will be collected by questionnaire. Companies and workers inclusion questionnaires are designed and currently under validation. This registration is at the moment planned for three years but could be extended and include other ENM. A prospective cohort study will be established from this registry, to pursue surveillance objectives and serve as an infrastructure for performing epidemiological and panel studies with specific research objectives.

  6. Proceedings of the Workshop on Risk Perception as Initiator and Steering Instrument of Innovative Research and Development

    Energy Technology Data Exchange (ETDEWEB)

    Foskolos, Konstantin; Schmid, Ruth [eds.

    1999-03-01

    This Workshop was organised jointly by the Paul Scherrer Institute and the Swiss Federal Institute of Technology (ETH Zurich) in the framework of the SINTER Network, an EU funded Concerted Action within the 4th EU Framework Programme. It was attended by 29 participants from 7 different countries. A prerequisite for ensuring, in the long term, the option of a safe, reliable and competitive nuclear energy supply with the existing competence in Europe, is the merging or networking of ongoing and planned research and development activities, to share tasks and efficiently use the still existing resources. In this context, it is necessary to assess the European and world wide innovation trends in nuclear technology and to bring the opinions regarding their prioritisation down to a common denominator. A key element of this process is the assessment of the social relevance of such innovation trends, i.e. how emerging developments can satisfy real needs of the public and vice versa. This encompasses also questions on the compatibility of nuclear energy with a sustainable development and its corresponding advantages and perspectives. The analysis of earlier developments (technical innovations that emerged as an answer to `public pressure` both in the domain of nuclear energy and within other technical domains (chemistry, transports, gene technology)) should provide the basis, which would allow such an assessment. Lectures delivered at the workshop on these subjects and accompanying discussions are collected in this volume. (author) figs., tabs., refs.

  7. French registry of workers handling engineered nanomaterials as an instrument of integrated system for surveillance and research

    International Nuclear Information System (INIS)

    Guseva Canu, I; Boutou-Kempf, O; Delabre, L; Ducamp, S; Iwatsubo, Y; Marchand, J L; Imbernon, E

    2013-01-01

    Despite the lack of data on the human health potential risks related to the engineered nanomaterials (ENM) exposure, ENM handling spreads in industry. The French government officially charged the InVS to develop an epidemiological surveillance of workers occupationally exposed to ENM. An initial surveillance plan was proposed on the basis of literature review and discussions with national and international ENM and occupational safety and health (OSH) experts. In site investigations and technical visits were then carried out to build an adequate surveillance system and to assess its feasibility. The current plan consists of a multi-step methodology where exposure registry construction is paramount. Workers potentially exposed to carbon nanotubes (CNT) or nanometric titanium dioxide (TiO 2 ) will be identified using a 3-level approach: 1-identification and selection of companies concerned with ENM exposure (based on compulsory declaration and questionnaires), 2-in site exposure assessment and identification of the jobs/tasks with ENM exposure (based on job-expose matrix, further supplemented with measurements), and 3-identification of workers concerned. Data of interest will be collected by questionnaire. Companies and workers inclusion questionnaires are designed and currently under validation. This registration is at the moment planned for three years but could be extended and include other ENM. A prospective cohort study will be established from this registry, to pursue surveillance objectives and serve as an infrastructure for performing epidemiological and panel studies with specific research objectives.

  8. Instrumental Capital

    Directory of Open Access Journals (Sweden)

    Gabriel Valerio

    2007-07-01

    Full Text Available During the history of human kind, since our first ancestors, tools have represented a mean to reach objectives which might otherwise seemed impossibles. In the called New Economy, where tangibles assets appear to be losing the role as the core element to produce value versus knowledge, tools have kept aside man in his dairy work. In this article, the author's objective is to describe, in a simple manner, the importance of managing the organization's group of tools or instruments (Instrumental Capital. The characteristic conditions of this New Economy, the way Knowledge Management deals with these new conditions and the sub-processes that provide support to the management of Instrumental Capital are described.

  9. WE-B-BRD-00: MRI for Radiation Oncology

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-06-15

    The use of MRI in radiation therapy is rapidly increasing. Applications vary from the MRI simulator, to the MRI fused with CT, and to the integrated MRI+RT system. Compared with the standard MRI QA, a broader scope of QA features has to be defined in order to maximize the benefits of using MRI in radiation therapy. These QA features include geometric fidelity, image registration, motion management, cross-system alignment, and hardware interference. Advanced MRI techniques require a specific type of QA, as they are being widely used in radiation therapy planning, dose calculations, post-implant dosimetry, and prognoses. A vigorous and adaptive QA program is crucial to defining the responsibility of the entire radiation therapy group and detecting deviations from the performance of high-quality treatment. As a drastic departure from CT simulation, MRI simulation requires changes in the work flow of treatment planning and image guidance. MRI guided radiotherapy platforms are being developed and commercialized to take the advantage of the advance in knowledge, technology and clinical experience. This symposium will from an educational perspective discuss the scope and specific issues related to MRI guided radiotherapy. Learning Objectives: Understand the difference between a standard and a radiotherapy-specific MRI QA program. Understand the effects of MRI artifacts (geometric distortion and motion) on radiotherapy. Understand advanced MRI techniques (ultrashort echo, fast MRI including dynamic MRI and 4DMRI, diffusion, perfusion, and MRS) and related QA. Understand the methods to prepare MRI for treatment planning (electron density assignment, multimodality image registration, segmentation and motion management). Current status of MRI guided treatment platforms. Dr. Jihong Wang has a research grant with Elekta-MRL project. Dr. Ke Sheng receives research grants from Varian Medical systems.

  10. FAST MRI breast screening revisited

    International Nuclear Information System (INIS)

    Jain, Manish; Jain, Arushi; Hyzy, Marek D.; Werth, Graziella

    2017-01-01

    Screening for breast cancer in high-risk women takes about 40 minutes to acquire an MRI scan and is time-intensive to report. There is recent interest in the performance of an abbreviated MRI protocol (FAST) in the screening setting. FAST scans have a reported negative predictive value of 99.8%. This study evaluates the false positive rates (FPR) and recall rates for FAST scans as compared to full diagnostic studies (FD). A database of all screening breast MRI scans performed at our institution between 30 June 2013 and 1 July 2014 (n = 591) was created by one of the researchers, who did not subsequently analyse the MRI scans. The T1W and first post-contrast and subtracted images from each of these scans (FAST protocol) were assessed by experienced breast MRI radiologists, blinded to the final diagnosis. The findings were then compared with the FD result. The recall rates were 6.6% for FAST scans and 5.8% for FD scans. FPR rates were 4.7% and 3.9% respectively. There is no statistically significant difference in the recall rates or FPR of FAST scans in comparison with full diagnostic studies. Given the absence of statistically significant difference in the FPR and recall rates in comparison with FD, FAST scans can replace FD for screening of breast cancer.

  11. The photographic knee pain map: locating knee pain with an instrument developed for diagnostic, communication and research purposes.

    Science.gov (United States)

    Elson, D W; Jones, S; Caplan, N; Stewart, S; St Clair Gibson, A; Kader, D F

    2011-12-01

    Pain maps are used to determine the location of pain. Knee pain maps have previously been described, but only one study has reported on reliability and none report validity. The present study describes the generation of a photographic knee pain map (PKPM) together with its validity and reliability. A photographic representation of a pair of knees was chosen by 26 patients, (66.7%) from a group of 39. The selected photograph was modified and a template of anatomical zones was generated. The opinions of 25 independent subject matter experts were canvassed and validity ratios calculated for these zones, ranged from 0.28 to 0.84. Hypothetical comparisons were made between the PKPM and an alternative knee pain map, in a cross-sectional group of 26 patients (35 knees). Convergent patterns of validity were found where hypothesised. Reliability was determined using a different cohort of 44 patients (58 knees) who completed the PKPM before and after a sampling delay. Four of these patients were excluded with a short sampling delay. Calculated agreement of test-retest reproducibility was fair to good. All of the completed PKPM (151 knees) were then subject to further analysis where inter-rater reproducibility was good to very good and intra-rater reproducibility was very good. The PKPM is readily accessible to patients with low completion burden. It is both valid and reliable and we suggest it can be used in both clinical and research settings. Further studies are planned to explore its predictive ability as a diagnostic tool. The PKPM can be found at www.photographickneepainmap.com. Copyright © 2010 Elsevier B.V. All rights reserved.

  12. Empirical studies on informal patient payments for health care services: a systematic and critical review of research methods and instruments

    Directory of Open Access Journals (Sweden)

    Pavlova Milena

    2010-09-01

    Full Text Available Abstract Background Empirical evidence demonstrates that informal patient payments are an important feature of many health care systems. However, the study of these payments is a challenging task because of their potentially illegal and sensitive nature. The aim of this paper is to provide a systematic review and analysis of key methodological difficulties in measuring informal patient payments. Methods The systematic review was based on the following eligibility criteria: English language publications that reported on empirical studies measuring informal patient payments. There were no limitations with regard to the year of publication. The content of the publications was analysed qualitatively and the results were organised in the form of tables. Data sources were Econlit, Econpapers, Medline, PubMed, ScienceDirect, SocINDEX. Results Informal payments for health care services are most often investigated in studies involving patients or the general public, but providers and officials are also sample units in some studies. The majority of the studies apply a single mode of data collection that involves either face-to-face interviews or group discussions. One of the main methodological difficulties reported in the publication concerns the inability of some respondents to distinguish between official and unofficial payments. Another complication is associated with the refusal of some respondents to answer questions on informal patient payments. We do not exclude the possibility that we have missed studies that reported in non-English language journals as well as very recent studies that are not yet published. Conclusions Given the recent evidence from research on survey methods, a self-administrated questionnaire during a face-to-face interview could be a suitable mode of collecting sensitive data, such as data on informal patient payments.

  13. Instrumental aspects

    Directory of Open Access Journals (Sweden)

    Qureshi Navid

    2017-01-01

    Full Text Available Every neutron scattering experiment requires the choice of a suited neutron diffractometer (or spectrometer in the case of inelastic scattering with its optimal configuration in order to accomplish the experimental tasks in the most successful way. Most generally, the compromise between the incident neutron flux and the instrumental resolution has to be considered, which is depending on a number of optical devices which are positioned in the neutron beam path. In this chapter the basic instrumental principles of neutron diffraction will be explained. Examples of different types of experiments and their respective expectable results will be shown. Furthermore, the production and use of polarized neutrons will be stressed.

  14. Magnetic Resonance Imaging (MRI) Safety

    Science.gov (United States)

    ... News Physician Resources Professions Site Index A-Z Magnetic Resonance Imaging (MRI) Safety What is MRI and how ... What is MRI and how does it work? Magnetic resonance imaging, or MRI, is a way of obtaining ...

  15. The Biographical Personality Interview (BPI)--a new approach to the assessment of premorbid personality in psychiatric research. Part I: Development of the instrument.

    Science.gov (United States)

    von Zerssen, D; Pössl, J; Hecht, H; Black, C; Garczynski, E; Barthelmes, H

    1998-01-01

    The Biographical Personality Interview (BPI) is a research instrument for the retrospective assessment of premorbid personality traits of psychiatric patients. Its construction is based on results of a series of investigations in which biographical data from psychiatric case notes were analysed with respect to premorbid personality traits. In order to avoid methodological shortcomings of the utilisation of clinical records, an interview technique was developed. It is applied by two independent, specially trained investigators who are kept "blind" regarding any clinical data of the subject under study. One of them has to conduct the interview of a clinically remitted patient and to provide an interview protocol, the other one has to rate personality traits from that protocol along a large series of purely descriptive items. Sum scores for six personality structures ("types") are calculated and the case is then assigned to the intra-individually dominating personality type according to the highest of these scores.

  16. Development of an Educational Game to Set Up Surgical Instruments on the Mayo Stand or Back Table: Applied Research in Production Technology.

    Science.gov (United States)

    Paim, Crislaine Pires Padilha; Goldmeier, Silvia

    2017-01-10

    Existing research suggests that digital games can be used effectively for educational purposes at any level of training. Perioperative nursing educators can use games to complement curricula, in guidance and staff development programs, to foster team collaboration, and to give support to critical thinking in nursing practice because it is a complex environment. To describe the process of developing an educational game to set up surgical instruments on the Mayo stand or back table as a resource to assist the instructor in surgical instrumentation training for students and nursing health professionals in continued education. The study was characterized by applied research in production technology. It included the phases of analysis and design, development, and evaluation. The objectives of the educational game were developed through Bloom's taxonomy. Parallel to the physical development of the educational game, a proposed model for the use of digital elements in educational game activities was applied to develop the game content. The development of the game called "Playing with Tweezers" was carried out in 3 phases and was evaluated by 15 participants, comprising students and professional experts in various areas of knowledge such as nursing, information technology, and education. An environment was created with an initial screen, menu buttons containing the rules of the game, and virtual tour modes for learning and assessment. The "digital" nursing student needs engagement, stimulation, reality, and entertainment, not just readings. "Playing with Tweezers" is an example of educational gaming as an innovative teaching strategy in nursing that encourages the strategy of involving the use of educational games to support theoretical or practical classroom teaching. Thus, the teacher does not work with only 1 type of teaching methodology, but with a combination of different methodologies. In addition, we cannot forget that skill training in an educational game does not

  17. MRI of the Chest

    Medline Plus

    Full Text Available ... examination poses almost no risk to the average patient when appropriate safety guidelines are followed. If sedation is used, there ... patient story here Images × ... Imaging (MRI) Safety Contrast Materials MRI Safety During Pregnancy Images related ...

  18. MRI of the Chest

    Medline Plus

    Full Text Available ... to a CD or uploaded to a digital cloud server. MRI of the chest gives detailed pictures ... over time. top of page What are the benefits vs. risks? Benefits MRI is a noninvasive imaging ...

  19. MRI of the Chest

    Medline Plus

    Full Text Available ... images and send a signed report to your primary care or referring physician, who will share the ... This detail makes MRI an invaluable tool in early diagnosis and evaluation of cardiovascular conditions. MRI has ...

  20. MRI of the Chest

    Medline Plus

    Full Text Available ... metallic items, which can distort MRI images removable dental work pens, pocket knives and eyeglasses body piercings In most cases, an MRI exam is safe for patients with metal implants, except for a few types. ...

  1. MRI of the Chest

    Medline Plus

    Full Text Available ... interfere with the magnetic field of the MRI unit, metal and electronic items are not allowed in ... does the equipment look like? The traditional MRI unit is a large cylinder-shaped tube surrounded by ...

  2. MRI of the Chest

    Medline Plus

    Full Text Available ... items, which can distort MRI images removable dental work pens, pocket knives and eyeglasses body piercings In most cases, an MRI exam is safe for patients with metal implants, except for a ...

  3. MRI of the Chest

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    Full Text Available ... metallic items, which can distort MRI images removable dental work pens, pocket knives and eyeglasses body piercings ... tomography (CT) scans, MRI does not utilize ionizing radiation. Instead, radiofrequency pulses re-align hydrogen atoms that ...

  4. MRI of the Chest

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    Full Text Available ... women should not have this exam in the first three to four months of pregnancy unless the ... not to have an MRI exam during the first trimester unless medically necessary. MRI may not always ...

  5. MRI of the Chest

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    Full Text Available ... important to assess the health and function of these structures (heart, valves, great vessels, etc.). top of ... room. In addition to affecting the MRI images, these objects can become projectiles within the MRI scanner ...

  6. MRI of the Chest

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    Full Text Available ... conditions. MRI uses a powerful magnetic field, radio frequency pulses and a computer to produce detailed pictures ... may follow your regular daily routine and take food and medications as usual. Some MRI examinations may ...

  7. MRI of the Chest

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    Full Text Available ... are the limitations of MRI of the Chest? What is MRI of the Chest? Magnetic resonance imaging ( ... heart, valves, great vessels, etc.). top of page What are some common uses of the procedure? MR ...

  8. MRI of the Chest

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    Full Text Available ... is done because a potential abnormality needs further evaluation with additional views or a special imaging technique. ... MRI an invaluable tool in early diagnosis and evaluation of cardiovascular conditions. MRI has proven valuable in ...

  9. MRI of the Chest

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    Full Text Available ... MRI scanners are air-conditioned and well-lit. Music may be played through the headphones to help ... used in MRI exams is less likely to produce an allergic reaction than the iodine-based contrast ...

  10. MRI of the Chest

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    Full Text Available ... or headphones during the exam. MRI scanners are air-conditioned and well-lit. Music may be played ... the limitations of MRI of the Chest? High-quality images are assured only if you are able ...

  11. MRI of the Chest

    Science.gov (United States)

    ... MRI scanners are air-conditioned and well-lit. Music may be played through the headphones to help ... tissue and fluid, known as edema . MRI typically costs more and may take more time to perform ...

  12. MRI of the Chest

    Medline Plus

    Full Text Available ... MRI scanners are air-conditioned and well-lit. Music may be played through the headphones to help ... tissue and fluid, known as edema . MRI typically costs more and may take more time to perform ...

  13. MRI of the Chest

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    Full Text Available ... clearer and more detailed than with other imaging methods. This detail makes MRI an invaluable tool in ... might be obscured by bone with other imaging methods. The contrast material used in MRI exams is ...

  14. MRI of the Chest

    Medline Plus

    Full Text Available ... top of page What are the benefits vs. risks? Benefits MRI is a noninvasive imaging technique that ... risking the side effects of conventional (catheter) angiography . Risks The MRI examination poses almost no risk to ...

  15. MRI of the Chest

    Medline Plus

    Full Text Available ... MRI examination poses almost no risk to the average patient when appropriate safety guidelines are followed. If ... tissue and fluid, known as edema . MRI typically costs more and may take more time to perform ...

  16. MRI of the Chest

    Medline Plus

    Full Text Available ... other internal body structures. MRI does not use ionizing radiation (x-rays). Detailed MR images allow physicians ... computed tomography (CT) scans, MRI does not utilize ionizing radiation. Instead, radiofrequency pulses re-align hydrogen atoms ...

  17. MRI of the Chest

    Medline Plus

    Full Text Available ... This detail makes MRI an invaluable tool in early diagnosis and evaluation of cardiovascular conditions. MRI has ... have special pediatric considerations. The teddy bear denotes child-specific content. Related Articles and Media MR Angiography ( ...

  18. Canalis basilaris medianus: MRI

    International Nuclear Information System (INIS)

    Jacquemin, C.; Bosley, T.M.; Al Saleh, M.; Mullaney, P.

    2000-01-01

    We report the MRI appearances of an developmental anatomical variant of the basiocciput, with neuroimaging findings (CT and MRI). Such variants are commonly asymptomatic, but may be associated with episodes of meningitis. (orig.)

  19. Surgical Instrument

    NARCIS (Netherlands)

    Dankelman, J.; Horeman, T.

    2009-01-01

    The present invention relates to a surgical instrument for minimall-invasive surgery, comprising a handle, a shaft and an actuating part, characterised by a gastight cover surrounding the shaft, wherein the cover is provided with a coupler that has a feed- through opening with a loskable seal,

  20. Weather Instruments.

    Science.gov (United States)

    Brantley, L. Reed, Sr.; Demanche, Edna L.; Klemm, E. Barbara; Kyselka, Will; Phillips, Edwin A.; Pottenger, Francis M.; Yamamoto, Karen N.; Young, Donald B.

    This booklet presents some activities to measure various weather phenomena. Directions for constructing a weather station are included. Instruments including rain gauges, thermometers, wind vanes, wind speed devices, humidity devices, barometers, atmospheric observations, a dustfall jar, sticky-tape can, detection of gases in the air, and pH of…

  1. An Electric Field Test Using the MRI

    Czech Academy of Sciences Publication Activity Database

    Fiala, P.; Bartušek, Karel

    2008-01-01

    Roč. 4, č. 7 (2008), s. 701-705 ISSN 1931-7360 Institutional research plan: CEZ:AV0Z20650511 Keywords : MRI * electric field * numerical modeling Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering

  2. MRI in acute poliomyelitis

    Energy Technology Data Exchange (ETDEWEB)

    Kornreich, L. [Imaging Department, The Schneider Children`s Medical Centre of Israel, Kaplan Street, Petah Tiqva 49202 (Israel)]|[Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (Israel); Dagan, O. [The Intensive Care Unit, The Schneider Children`s Medical Centre of Israel, Beilinson Medical Campus, Petah Tiqva (Israel)]|[Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (Israel); Grunebaum, M. [Imaging Department, The Schneider Children`s Medical Centre of Israel, Kaplan Street, Petah Tiqva 49202 (Israel)]|[Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (Israel)

    1996-05-01

    MRI can be used in the diagnosis of anterior horn infection and for assessing the extent of disease. There are no specific MRI signs to differentiate between the various possible pathogens. This is demonstrated in the present case of poliomyelitis, in which MRI of the spine played an important role in establishing the diagnosis. (orig.). With 1 fig.

  3. MRI in acute poliomyelitis

    International Nuclear Information System (INIS)

    Kornreich, L.; Dagan, O.; Grunebaum, M.

    1996-01-01

    MRI can be used in the diagnosis of anterior horn infection and for assessing the extent of disease. There are no specific MRI signs to differentiate between the various possible pathogens. This is demonstrated in the present case of poliomyelitis, in which MRI of the spine played an important role in establishing the diagnosis. (orig.). With 1 fig

  4. [Fusion of MRI, fMRI and intraoperative MRI data. Methods and clinical significance exemplified by neurosurgical interventions].

    Science.gov (United States)

    Moche, M; Busse, H; Dannenberg, C; Schulz, T; Schmitgen, A; Trantakis, C; Winkler, D; Schmidt, F; Kahn, T

    2001-11-01

    The aim of this work was to realize and clinically evaluate an image fusion platform for the integration of preoperative MRI and fMRI data into the intraoperative images of an interventional MRI system with a focus on neurosurgical procedures. A vertically open 0.5 T MRI scanner was equipped with a dedicated navigation system enabling the registration of additional imaging modalities (MRI, fMRI, CT) with the intraoperatively acquired data sets. These merged image data served as the basis for interventional planning and multimodal navigation. So far, the system has been used in 70 neurosurgical interventions (13 of which involved image data fusion--requiring 15 minutes extra time). The augmented navigation system is characterized by a higher frame rate and a higher image quality as compared to the system-integrated navigation based on continuously acquired (near) real time images. Patient movement and tissue shifts can be immediately detected by monitoring the morphological differences between both navigation scenes. The multimodal image fusion allowed a refined navigation planning especially for the resection of deeply seated brain lesions or pathologies close to eloquent areas. Augmented intraoperative orientation and instrument guidance improve the safety and accuracy of neurosurgical interventions.

  5. [Research on K-means clustering segmentation method for MRI brain image based on selecting multi-peaks in gray histogram].

    Science.gov (United States)

    Chen, Zhaoxue; Yu, Haizhong; Chen, Hao

    2013-12-01

    To solve the problem of traditional K-means clustering in which initial clustering centers are selected randomly, we proposed a new K-means segmentation algorithm based on robustly selecting 'peaks' standing for White Matter, Gray Matter and Cerebrospinal Fluid in multi-peaks gray histogram of MRI brain image. The new algorithm takes gray value of selected histogram 'peaks' as the initial K-means clustering center and can segment the MRI brain image into three parts of tissue more effectively, accurately, steadily and successfully. Massive experiments have proved that the proposed algorithm can overcome many shortcomings caused by traditional K-means clustering method such as low efficiency, veracity, robustness and time consuming. The histogram 'peak' selecting idea of the proposed segmentootion method is of more universal availability.

  6. Versatile intraoperative MRI in neurosurgery and radiology.

    Science.gov (United States)

    Yrjänä, S K; Katisko, J P; Ojala, R O; Tervonen, O; Schiffbauer, H; Koivukangas, J

    2002-03-01

    Several models for the application of intra-operative magnetic resonance imaging (IMRI) have recently been reported, most of them unique. Two fundamental issues need to be addressed: optimal use of the scanner to ensure a wide base for research, development and clinical application, and an organisational model that facilitates such use. While in our setting the IMRI project was initiated by the neurosurgeons, the need for wider use of the facilities was recognised since the beginning of the planning phase in 1996. An organisational model was developed that allowed for development of neurosurgical applications, radiological imaging, and radiological interventions and for the research and development work of the vendor. A resistive 0.23 T MR scanner was installed in a dedicated operating room environment. Unique to this scanner is the ability to turn off the magnet, allowing for normal OR activities and devices, and to turn on the magnet as needed with a relatively short six-minute ramp up time. A staged surgical technique was perfected, allowing for transfer of data to the neuronavigator outside the scanner during surgery. In neurosurgery, IMRI was used as one part of a neuronavigational system that included ultrasound imaging, intra-operative cortical stimulation during awake procedures, electrocorticography and two neuronavigators. 34 neurosurgical cases included 27 brain tumour resections, 5 brain tumour biopsies, 1 extirpation of an arterio-venous malformation, and 1 haematoma evacuation. The scanner could also be used for normal clinical imaging where obese patients, children, claustophobic patients and postoperative control examinations were the major groups. The radiologists performed 110 interventions, including bone and abdominal biopsies, nerve root infiltrations and local pain therapies, with the optical needle tracking system under continuous MRI guidance. The organisational model allowed frequent use of the facilities for both neurosurgery and radiology

  7. MRI: update on technology diffusion and acquisition.

    Science.gov (United States)

    Hoppszallern, S; Hughes, C; Zimmerman, R A

    1991-04-01

    Over the past three years, magnetic resonance imaging (MRI) has become accepted as a valuable diagnostic tool, and its applications continue to expand. During this time, the number of units installed in the United States doubled. By 1990 about 2,000 MRI units were in place in the United States and nearly 20 percent of the MRI-installed base was mobile, according to a research study conducted by the Hadley Hart Group (Chicago) and Drew Consultants, Inc. (Concord, MA). With the introduction of the prospective payment system, many hospitals were hesitant to spend limited capital on new technology, such as MRI. At the same time, freestanding diagnostic imaging centers were on the rise. Some hospitals and entrepreneurs who foresaw the potential of MRI in health care pioneered its use in the clinical setting. Hospitals began to examine new partnership arrangements and alternative forms of financing, so that they too could offer MRI services. By the end of 1988, the majority of hospitals offering MRI services did not own their own unit and about 40 percent of the hospitals offering MRI services were in a mobile configuration according to the Hadley Hart Group. While the technology has been diffused into 100-bed hospitals via mobile service vendors in some parts of the country, many medium-sized and large hospitals also have entered the MRI services market in this fashion. In the larger hospitals, the patient demand or need for the service often would justify acquisition of MRI, but the expense of the technology, and in many areas restrictive state health planning policies, modified purchase of MRI systems by hospitals. Mobile service vendors offered hospitals a way to startup MRI services in a limited fashion without a major capital expenditure and its associated risk. As hospitals gain experience with mobile MRI and achieve or exceed their early utilization projections, administrators are reevaluating the need to expand services to a full-time fixed site. Early fixed

  8. Organizational readiness to change assessment (ORCA: Development of an instrument based on the Promoting Action on Research in Health Services (PARIHS framework

    Directory of Open Access Journals (Sweden)

    Li Yu-Fang

    2009-07-01

    Full Text Available Abstract Background The Promoting Action on Research Implementation in Health Services, or PARIHS, framework is a theoretical framework widely promoted as a guide to implement evidence-based clinical practices. However, it has as yet no pool of validated measurement instruments that operationalize the constructs defined in the framework. The present article introduces an Organizational Readiness to Change Assessment instrument (ORCA, organized according to the core elements and sub-elements of the PARIHS framework, and reports on initial validation. Methods We conducted scale reliability and factor analyses on cross-sectional, secondary data from three quality improvement projects (n = 80 conducted in the Veterans Health Administration. In each project, identical 77-item ORCA instruments were administered to one or more staff from each facility involved in quality improvement projects. Items were organized into 19 subscales and three primary scales corresponding to the core elements of the PARIHS framework: (1 Strength and extent of evidence for the clinical practice changes represented by the QI program, assessed with four subscales, (2 Quality of the organizational context for the QI program, assessed with six subscales, and (3 Capacity for internal facilitation of the QI program, assessed with nine subscales. Results Cronbach's alpha for scale reliability were 0.74, 0.85 and 0.95 for the evidence, context and facilitation scales, respectively. The evidence scale and its three constituent subscales failed to meet the conventional threshold of 0.80 for reliability, and three individual items were eliminated from evidence subscales following reliability testing. In exploratory factor analysis, three factors were retained. Seven of the nine facilitation subscales loaded onto the first factor; five of the six context subscales loaded onto the second factor; and the three evidence subscales loaded on the third factor. Two subscales failed to load

  9. Organizational readiness to change assessment (ORCA): development of an instrument based on the Promoting Action on Research in Health Services (PARIHS) framework.

    Science.gov (United States)

    Helfrich, Christian D; Li, Yu-Fang; Sharp, Nancy D; Sales, Anne E

    2009-07-14

    The Promoting Action on Research Implementation in Health Services, or PARIHS, framework is a theoretical framework widely promoted as a guide to implement evidence-based clinical practices. However, it has as yet no pool of validated measurement instruments that operationalize the constructs defined in the framework. The present article introduces an Organizational Readiness to Change Assessment instrument (ORCA), organized according to the core elements and sub-elements of the PARIHS framework, and reports on initial validation. We conducted scale reliability and factor analyses on cross-sectional, secondary data from three quality improvement projects (n = 80) conducted in the Veterans Health Administration. In each project, identical 77-item ORCA instruments were administered to one or more staff from each facility involved in quality improvement projects. Items were organized into 19 subscales and three primary scales corresponding to the core elements of the PARIHS framework: (1) Strength and extent of evidence for the clinical practice changes represented by the QI program, assessed with four subscales, (2) Quality of the organizational context for the QI program, assessed with six subscales, and (3) Capacity for internal facilitation of the QI program, assessed with nine subscales. Cronbach's alpha for scale reliability were 0.74, 0.85 and 0.95 for the evidence, context and facilitation scales, respectively. The evidence scale and its three constituent subscales failed to meet the conventional threshold of 0.80 for reliability, and three individual items were eliminated from evidence subscales following reliability testing. In exploratory factor analysis, three factors were retained. Seven of the nine facilitation subscales loaded onto the first factor; five of the six context subscales loaded onto the second factor; and the three evidence subscales loaded on the third factor. Two subscales failed to load significantly on any factor. One measured resources

  10. Research on Neuromarketing-introduction of fMRI%神经营销学研究现状——fMRI成果评述

    Institute of Scientific and Technical Information of China (English)

    杜建刚; 王琳

    2012-01-01

    神经营销学从产生至今尚不足十年,虽然基于fMRI的脑核磁共振技术早已应用到企业实践中,但在学术领域还是饱受争议。本文从产品、购买决策、广告、品牌、满意及忠诚等几方面回顾了自神经营销产生至今的学术文献,并且深入评述了神经营销方法应用在营销理论中的优势和局限性。最后,本文对神经营销学在市场营销中的应用前景进行了展望。%Neuromarketing is a sub-area of neuroeconomics that addresses marketing relevant problems with methods and insights from brain research. Neuromarketing is still less than a decade since it emerged. Although Magnetic Resonance Imaging (fMRI) has already applied to the practice by marketing practicers, it is controversial in the academic field. The authors reviewed the situation of foreign and domestic neuromarketing academic papers which have already been published. Against this background, this paper showed the most prominent brain structures relevant for consumer neuroscience, and presented specific results of selected studies from this emerging discipline, classified from the aspect of product, price, customer's buying decision, advertisement, brand, customer's preferences, survice marketing, customer's satisfaction and loyalty, and so on. The strength of fMRI is discussed lately. Firstly, with the help of advanced techniques of neuromarketing, a more direct view into the "black box" of the organism should be feasible, and scientific and effective marketing strategies for commercial enterprises could be developed by managers as well. With regard to long-term product strategy, neuromarketing could be used to determine which consumer segments are reached by advertisement strategies, or whether a future purchase of the brand is probable. Secondly, with the proliferation of dazzling images from brain scans in both scientific and popular media, researchers from marketing fields could see that not

  11. A Demonstration of an Improved Filtering Technique for Analyzing Climate Records via Comparisons of Satellite MSU/AMSU Instrument Temperature Products from Three Research Groups

    Science.gov (United States)

    Swanson, R. E.

    2017-12-01

    Climate data records typically exhibit considerable variation over short time scales both from natural variability and from instrumentation issues. The use of linear least squares regression can provide overall trend information from noisy data, however assessing intermediate time periods can also provide useful information unavailable from basic trend calculations. Extracting the short term information in these data for assessing changes to climate or for comparison of data series from different sources requires the application of filters to separate short period variations from longer period trends. A common method used to smooth data is the moving average, which is a simple digital filter that can distort the resulting series due to the aliasing of the sampling period into the output series. We utilized Hamming filters to compare MSU/AMSU satellite time series developed by three research groups (UAH, RSS and NOAA STAR), the results published in January 2017 [http://journals.ametsoc.org/doi/abs/10.1175/JTECH-D-16-0121.1]. Since the last release date (July 2016) for the data analyzed in that paper, some of these groups have updated their analytical procedures and additional months of data are available to extend the series. An updated analysis of these data using the latest data releases available from each group is to be presented. Improved graphics will be employed to provide a clearer visualization of the differences between each group's results. As in the previous paper, the greatest difference between the UAH TMT series and those from the RSS and NOAA data appears during the early period of data from the MSU instruments before about 2003, as shown in the attached figure, and preliminary results indicate this pattern continues. Also to be presented are other findings regarding seasonal changes which were not included in the previous study.

  12. Research study of pressure instrumentation

    Science.gov (United States)

    Hoogenboom, L.; Hull-Allen, G.

    1984-01-01

    To obtain a more vibration resistant pressure sensor for use on the Space Shuttle Main Engine, a proximity probe based, diaphragm type pressure sensor breadboard was developed. A fiber optic proximity probe was selected as the sensor. In combination with existing electronics, a thermal stability evaluation of the entire probe system was made. Based upon the results, a breadboard design of the pressure sensor and electronics was made and fabricated. A brief series of functional experiments was made with the breadboard to calibrate, thermally compensate, and linearize its response. In these experiments, the performance obtained in the temperature range of -320 F (liquid N2) to +200 F was comparable to that of the strain gage based sensor presently in use on the engine. In tests at NASA-Marshall Space Flight Center (MSFC), after some time at or near liquid nitrogen temperatures, the sensor output varied over the entire output range. These large spurious signals were attributed to condensation of air in the sensing gap. In the next phase of development of this sensor, an evaluation of fabrication techniques toward greater thermal and mechanical stability of the fiber probe assembly must be made. In addition to this, a positive optics to metal seal must be developed to withstand the pressure that would result from a diaphragm failure.

  13. Divided Instruments

    Science.gov (United States)

    Chapman, A.; Murdin, P.

    2000-11-01

    Although the division of the zodiac into 360° probably derives from Egypt or Assyria around 2000 BC, there is no surviving evidence of Mesopotamian cultures embodying this division into a mathematical instrument. Almost certainly, however, it was from Babylonia that the Greek geometers learned of the 360° circle, and by c. 80 BC they had incorporated it into that remarkably elaborate device gener...

  14. Instrumentation development

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    Areas being investigated for instrumentation improvement during low-level pollution monitoring include laser opto-acoustic spectroscopy, x-ray fluorescence spectroscopy, optical fluorescence spectroscopy, liquid crystal gas detectors, advanced forms of atomic absorption spectroscopy, electro-analytical chemistry, and mass spectroscopy. Emphasis is also directed toward development of physical methods, as opposed to conventional chemical analysis techniques for monitoring these trace amounts of pollution related to energy development and utilization

  15. Rapid instrumental and separation methods for monitoring radionuclides in food and environmental samples. Final report on an IAEA co-ordinated research programme

    International Nuclear Information System (INIS)

    1995-01-01

    The Co-ordinated Research Programme (CRP) on Rapid Instrumental and Separation Methods for Monitoring Radionuclides in Food and Environmental Samples was established by the Agency following a Consultants' Meeting on the same topic, which was held 5-9 September 1988 in Vienna. It was completed in 1992. At various times during its course it encompassed 15 participants from 14 countries. The scope of work and objectives of the CRP were established at the Consultants' Meeting. It was agreed that the CRP should focus on the development of rapid methods for the determination of radionuclides in food and environmental samples during the intermediate and late post-accident phases. The rapid methods developed during the course of the CRP were intended to permit a timely and accurate determination of radionuclides at concentrations at least one order of magnitude below those specified for Derived Intervention Levels (DILs) for food by the WHO/FAO and the IAEA. Research Co-ordination meetings were held in Warsaw, Poland in September 1989 and in Vienna, Austria in 1991. Reports of the meetings are available from the Agency on Request. This document comprises copies of final reports from the participants and selected contributions presented by the participants at the meetings. The contributions were selected on the basis of being able to stand alone, without further explanation. Where there was an overlap in the information presented by a participant at both meetings, the most complete contribution was selected

  16. Observations of fine-scale transport structure in the upper troposphere from the High-performance Instrumented Airborne Platform for Environmental Research

    Science.gov (United States)

    Bowman, Kenneth P.; Pan, Laura L.; Campos, Teresa; Gao, Rushan

    2007-09-01

    The Progressive Science Mission in December 2005 was the first research use of the new NCAR High-performance Instrumented Airborne Platform for Environmental Research (HIAPER) aircraft. The Stratosphere-Troposphere Analyses of Regional Transport (START) component of the mission was designed to investigate the dynamical and chemical structure of the upper troposphere and lower stratosphere. Flight 5 of the Progressive Science mission was a START flight that sampled near the tropopause in an area between the main jet stream and a large, quasi-stationary, cutoff low. The large-scale flow in this region was characterized by a hyperbolic (saddle) point. In this study the in situ measurements by HIAPER are combined with flow analyses and satellite data to investigate the quasi-isentropic stirring of trace species in the upper troposphere. As expected from theoretical considerations, strong stretching and folding deformation of the flow near the hyperbolic point resulted in rapid filamentation of air masses and sharp gradients of constituents. Calculations of the stirring using operational meteorological analyses from the NCEP Global Forecast System model produced excellent agreement with HIAPER and satellite observations of trace species. Back trajectories indicate that elevated ozone levels in some filaments likely came from a large stratospheric intrusion that occurred upstream in the jet over the north Pacific Ocean. The methods presented here can be used with operational forecasts for future flight planning.

  17. Rapid instrumental and separation methods for monitoring radionuclides in food and environmental samples. Final report on an IAEA co-ordinated research programme

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    The Co-ordinated Research Programme (CRP) on Rapid Instrumental and Separation Methods for Monitoring Radionuclides in Food and Environmental Samples was established by the Agency following a Consultants' Meeting on the same topic, which was held 5-9 September 1988 in Vienna. It was completed in 1992. At various times during its course it encompassed 15 participants from 14 countries. The scope of work and objectives of the CRP were established at the Consultants' Meeting. It was agreed that the CRP should focus on the development of rapid methods for the determination of radionuclides in food and environmental samples during the intermediate and late post-accident phases. The rapid methods developed during the course of the CRP were intended to permit a timely and accurate determination of radionuclides at concentrations at least one order of magnitude below those specified for Derived Intervention Levels (DILs) for food by the WHO/FAO and the IAEA. Research Co-ordination meetings were held in Warsaw, Poland in September 1989 and in Vienna, Austria in 1991. Reports of the meetings are available from the Agency on Request. This document comprises copies of final reports from the participants and selected contributions presented by the participants at the meetings. The contributions were selected on the basis of being able to stand alone, without further explanation. Where there was an overlap in the information presented by a participant at both meetings, the most complete contribution was selected.

  18. The IKARUS instrument

    International Nuclear Information System (INIS)

    Gerster, H.J.; Stein, G.

    1994-01-01

    When the Federal Government decided on a 25% reduction of CO 2 emissions till 2005 in 1990 the necessity resulted that an instrument has to be developed for the analysis and assessment of the ecological, economic and energetic impact of different reduction strategies. The development task was awarded by the BMFT to the Research Centre Juelich in cooperation with well-known institutions of energy system research. The total instrument is scheduled to be finished by the end of 1994. For the decentral use of the instrument by a wide specialist public the developed models and data banks which are equipped with a user-friendly surface are suited for larger PCs (486, 16 MB RAM/500-1000 MB ROM). (orig.) [de

  19. ACRF Instrumentation Status and Information September 2009

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2009-10-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  20. ACRF Instrumentation Status and Information April 2009

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2009-05-07

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  1. ACRF Instrumentation Status and Information August 2009

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2009-09-09

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  2. ACRF Instrumentation Status and Information July 2009

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2009-08-13

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  3. ACRF Instrumentation Status and Information - June 2009

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2009-06-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  4. ACRF Instrumentation Status and Information May 2009

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2009-05-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  5. Design, fabrication and irradiation test report on HANARO instrumented capsule (05M-07U) for the researches of universities in 2005

    Energy Technology Data Exchange (ETDEWEB)

    Choo, K. N.; Kim, B. G.; Kang, Y. H.; Choi, M. H.; Cho, M. S.; Son, J. M.; Choi, M. H.; Shin, Y. T.; Park, S. J.

    2006-09-15

    As a part of the 2005 project for an active utilization of HANARO, an instrumented capsule (05M-07U) was designed, fabricated and irradiated for an irradiation test of various unclear materials under irradiation conditions which was requested by external researchers from universities. The basic structure of the 05M-07U capsule was based on the 00M-01U, 01M-05U, 02M-05U, 03M-06U and 04M-07U capsules which had been successfully irradiated in HANARO as part of the 2000, 2001, 2002, 2003 and 2004 projects. However, because of a limited number of specimens and the budget of one university, the remaining space in the capsule was filled with various KAERI specimens for researches on a nuclear core and SMART materials, and parts of a nuclear fuel assembly of KNFC. Various types of specimens such as tensile, Charpy, TEM, hardness, compression and growth specimens made of Zr 702, Ti and Ni alloys, Zirlo, Inconel, STS 316L and Cr-Mo alloys were placed in the capsule. Especially, this capsule was designed to evaluate the nuclear characteristics of the parts of a nuclear fuel assembly and the Ti tubes in HANARO. The capsule was composed of 5 stages having many kinds of specimens and an independent electric heater at each stage. During the irradiation test, the temperature of the specimens and the thermal/fast neutron fluences were measured by 14 thermocouples and 5 sets of Ni-Ti-Fe neutron fluence monitors installed in the capsule. The capsule was irradiated in the CT test hole of HANARO of a 30MW thermal output at 270 ∼ 400 .deg. C up to a fast neutron fluence of 5.7 x 10{sup 20} (n/cm{sup 2}) (E >1.0MeV). The obtained results will be very valuable for the related research of the users.

  6. Imaging tools to study pharmacology: functional MRI on small rodents

    Directory of Open Access Journals (Sweden)

    Elisabeth eJonckers

    2015-10-01

    Full Text Available Functional Magnetic Resonance Imaging (fMRI is an excellent tool to study the effect of pharmacological modulations on brain function in a non-invasive and longitudinal manner. We introduce several blood oxygenation level dependent (BOLD fMRI techniques, including resting state (rsfMRI, stimulus-evoked (st-fMRI, and pharmacological MRI (phMRI. Respectively, these techniques permit the assessment of functional connectivity during rest as well as brain activation triggered by sensory stimulation and/or a pharmacological challenge. The first part of this review describes the physiological basis of BOLD fMRI and the hemodynamic response on which the MRI contrast is based. Specific emphasis goes to possible effects of anaesthesia and the animal’s physiological conditions on neural activity and the hemodynamic response. The second part of this review describes applications of the aforementioned techniques in pharmacologically-induced, as well as in traumatic and transgenic disease models and illustrates how multiple fMRI methods can be applied successfully to evaluate different aspects of a specific disorder. For example, fMRI techniques can be used to pinpoint the neural substrate of a disease beyond previously defined hypothesis-driven regions-of-interest (ROIs. In addition, fMRI techniques allow one to dissect how specific modifications (e.g. treatment, lesion etc. modulate the functioning of specific brain areas (st-fMRI, phMRI and how functional connectivity (rsfMRI between several brain regions is affected, both in acute and extended time frames. Furthermore, fMRI techniques can be used to assess/explore the efficacy of novel treatments in depth, both in fundamental research as well as in preclinical settings. In conclusion, by describing several exemplary studies, we aim to highlight the advantages of functional MRI in exploring the acute and long-term effects of pharmacological substances and/or pathology on brain functioning along with

  7. IClinfMRI Software for Integrating Functional MRI Techniques in Presurgical Mapping and Clinical Studies.

    Science.gov (United States)

    Hsu, Ai-Ling; Hou, Ping; Johnson, Jason M; Wu, Changwei W; Noll, Kyle R; Prabhu, Sujit S; Ferguson, Sherise D; Kumar, Vinodh A; Schomer, Donald F; Hazle, John D; Chen, Jyh-Horng; Liu, Ho-Ling

    2018-01-01

    Task-evoked and resting-state (rs) functional magnetic resonance imaging (fMRI) techniques have been applied to the clinical management of neurological diseases, exemplified by presurgical localization of eloquent cortex, to assist neurosurgeons in maximizing resection while preserving brain functions. In addition, recent studies have recommended incorporating cerebrovascular reactivity (CVR) imaging into clinical fMRI to evaluate the risk of lesion-induced neurovascular uncoupling (NVU). Although each of these imaging techniques possesses its own advantage for presurgical mapping, a specialized clinical software that integrates the three complementary techniques and promptly outputs the analyzed results to radiology and surgical navigation systems in a clinical format is still lacking. We developed the Integrated fMRI for Clinical Research (IClinfMRI) software to facilitate these needs. Beyond the independent processing of task-fMRI, rs-fMRI, and CVR mapping, IClinfMRI encompasses three unique functions: (1) supporting the interactive rs-fMRI mapping while visualizing task-fMRI results (or results from published meta-analysis) as a guidance map, (2) indicating/visualizing the NVU potential on analyzed fMRI maps, and (3) exporting these advanced mapping results in a Digital Imaging and Communications in Medicine (DICOM) format that are ready to export to a picture archiving and communication system (PACS) and a surgical navigation system. In summary, IClinfMRI has the merits of efficiently translating and integrating state-of-the-art imaging techniques for presurgical functional mapping and clinical fMRI studies.

  8. Instrumentation in thermoluminescence dosimetry

    International Nuclear Information System (INIS)

    Julius, H.W.

    1986-01-01

    In the performance of a thermoluminescence dosimetry (TLD) system the equipment plays an important role. Crucial parameters of instrumentation in TLD are discussed in some detail. A review is given of equipment available on the market today - with some emphasis on automation - which is partly based on information from industry and others involved in research and development. (author)

  9. PET-MRI and multimodal cancer imaging

    International Nuclear Information System (INIS)

    Wang Taisong; Zhao Jinhua; Song Jianhua

    2011-01-01

    Multimodality imaging, specifically PET-CT, brought a new perspective into the fields of clinical imaging. Clinical cases have shown that PET-CT has great value in clinical diagnosis and experimental research. But PET-CT still bears some limitations. A major drawback is that CT provides only limited soft tissue contrast and exposes the patient to a significant radiation dose. MRI overcome these limitations, it has excellent soft tissue contrast, high temporal and spatial resolution and no radiation damage. Additionally, since MRI provides also functional information, PET-MRI will show a new direction of multimodality imaging in the future. (authors)

  10. 6th interventional MRI symposium. Abstracts

    International Nuclear Information System (INIS)

    2006-01-01

    The ongoing progress in the field of interventional MRI and the great success of our last symposium 2004 in Boston have stimulated us to organize the 6th Interventional MRI Symposium to be held September 15-16, 2006 in Leipzig. This meeting will highlight ground-breaking research as well as cutting-edge reports from many groups. The symposium also provides a forum to network with leaders and innovators in the field. Session topics are: intraoperative MRI, vascular applications, targeted drug delivery, cryotherapy, thermometry, pulse sequences, LITT, percutaneous procedures, navigation, robotics, focused ultrasound. (uke)

  11. 6{sup th} interventional MRI symposium. Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The ongoing progress in the field of interventional MRI and the great success of our last symposium 2004 in Boston have stimulated us to organize the 6th Interventional MRI Symposium to be held September 15-16, 2006 in Leipzig. This meeting will highlight ground-breaking research as well as cutting-edge reports from many groups. The symposium also provides a forum to network with leaders and innovators in the field. Session topics are: intraoperative MRI, vascular applications, targeted drug delivery, cryotherapy, thermometry, pulse sequences, LITT, percutaneous procedures, navigation, robotics, focused ultrasound. (uke)

  12. Safety Research Program for Light Water Reactors. Technical report 2: BMFT support project RS 0036 B. Reflooding experiments with regard to primary circuits (PKL) instrumentation of experimental setup

    International Nuclear Information System (INIS)

    Schweickert, H.; Mandl, R.

    The reflooding of the hot core of a PWR will be investigated in a model of the complete primary system. The demands that the instrumentation must meet as well as a description of the measurement methods used in the circuit are described. Data on the efficiency of the instruments, error estimates and constructive solutions to design problems are also given

  13. Youth Quality of Life Instrument-Research version (YQOL-R: propriedades psicométricas em uma amostra comunitária

    Directory of Open Access Journals (Sweden)

    Giovanni Abrahão Salum

    2012-10-01

    Full Text Available OBJETIVO: Testar algumas propriedades psicométricas da versão brasileira do Youth Quality of Life Instrument-Research (YQOL-R em uma amostra comunitária de adolescentes brasileiros. MÉTODOS: Este é um estudo transversal comunitário realizado em seis escolas localizadas na área de abrangência de uma unidade de saúde da família. De uma população original de 2.754 estudantes com idade entre 10 e 17 anos, selecionamos aleatoriamente 419 para responder à versão brasileira do YQOL-R. Testamos a confiabilidade, as diferenças já conhecidas entre os grupos (utilizando sintomas de ansiedade e envolvimento em episódios de bullying e a estrutura fatorial. RESULTADOS: O YQOL-R apresentou boa consistência interna, e as diferenças já conhecidas entre os grupos mostraram-se adequadas e estiveram dentro do esperado tanto com relação ao bullying quanto à ansiedade. A estrutura fatorial do modelo conceitual foi em parte fundamentada por nossa análise. CONCLUSÕES: A versão brasileira do YQOL-R apresentou propriedades psicométricas suficientemente boas. São necessários mais estudos a fim de melhor investigar configurações alternativas da estrutura fatorial.

  14. Possible role of MRI in the follow-up of the renal transplants

    International Nuclear Information System (INIS)

    Gremo, L.; Avatenello, T.; Borre', A.; Potenzoni, F.; Colla, L.; Segolini, G.

    1988-01-01

    The authors discuss the possible role of Magnetic Resonance Imaging (MRI) in the follow-up of renal transplants. Its diagnostic accuracy is compared with Ultrasounds (US), which is considered the method of choice in postoperative monitoring of renal transplants. Thirty-two patients (transplant life ranging from 5 days to 37 months) were examined in the same day with both MRI and US. Sonographic evaluation is based on a group of signs related to renal alteration and unanimously ascertained; the identification of MR patterns of normally functioning kidney or renal rejection might give way to more extensive clinical applications of the method, with the advantages of multiplanarity and no X-ray use. MR diagnostic accuracy in the diagnosis of normally functioning transplant or renal rejection was 82.7% (vs. US: 68.9% vs. 656.25%). MRI is more sensitive in demonstrating renal pathology in transplanted kidneys, and its diagnostic accuracy is superior. Still, US must be considered the methodology of choice in instrumental research when there is a clinical suspicion of renal rejection, due to its sufficient diagnostic accuracy, to its being easy to perform in continuous follow-up, to its low cost and to the short execution time. MRI is nevertheless suggested in the follow-up of renal transplants both in questionable cases and when biopsy cannot be performed

  15. MRI in psychiatry

    International Nuclear Information System (INIS)

    Mulert, Christoph; Shenton, Martha E.

    2014-01-01

    This is the first comprehensive textbook on the use of MRI in psychiatry covering imaging techniques, brain systems and a review of findings in different psychiatric disorders. The book is divided into three sections, the first of which covers in detail all the major MRI-based methodological approaches available today, including fMRI, EEG-fMRI, DTI, and MR spectroscopy. In addition, the role of MRI in imaging genetics and combined brain stimulation and imaging is carefully explained. The second section provides an overview of the different brain systems that are relevant for psychiatric disorders, including the systems for perception, emotion, cognition, and reward. The final part of the book presents the MRI findings that are obtained in all the major psychiatric disorders using the previously discussed techniques. Numerous carefully chosen images support the informative text, making this an ideal reference work for all practitioners and trainees with an interest in this flourishing field.

  16. MRI in psychiatry

    Energy Technology Data Exchange (ETDEWEB)

    Mulert, Christoph [UKE, Hamburg (Germany). Psychiatry Neuroimaging Branch; Shenton, Martha E. (ed.) [Harvard Medical School, Boston, MA (United States). Dept. of Psychiatry and Radiology

    2014-07-01

    This is the first comprehensive textbook on the use of MRI in psychiatry covering imaging techniques, brain systems and a review of findings in different psychiatric disorders. The book is divided into three sections, the first of which covers in detail all the major MRI-based methodological approaches available today, including fMRI, EEG-fMRI, DTI, and MR spectroscopy. In addition, the role of MRI in imaging genetics and combined brain stimulation and imaging is carefully explained. The second section provides an overview of the different brain systems that are relevant for psychiatric disorders, including the systems for perception, emotion, cognition, and reward. The final part of the book presents the MRI findings that are obtained in all the major psychiatric disorders using the previously discussed techniques. Numerous carefully chosen images support the informative text, making this an ideal reference work for all practitioners and trainees with an interest in this flourishing field.

  17. Superconductive MRI system, FLEXARTTM

    International Nuclear Information System (INIS)

    Suzuki, Hirokazu; Nishikawa, Mineki; Goro, Takehiko

    1994-01-01

    Since the establishment of TAMI (Toshiba America MRI Inc.) in 1989, it has been jointly working with Toshiba on developing a new infrastructure for computer and software technologies to be applied to new MRI (magnetic resonance imaging) systems. As a result of these efforts, the first product of a new series of MRI systems has been introduced on the market. Known as FLEXART TM (a newly created word combining FLEXible and ART), this MRI system incorporates a new 32-bit RISC computer and a new controller for pulse sequences and data acquisition. The product concepts of FLEXART TM are high image quality, high patient throughput, and ease of use, all of which are necessary features for an MRI system in the premium mid-field MRI market segment. (author)

  18. Quantitative analysis of organizational culture in occupational health research: a theory-based validation in 30 workplaces of the organizational culture profile instrument

    Science.gov (United States)

    2013-01-01

    Background This study advances a measurement approach for the study of organizational culture in population-based occupational health research, and tests how different organizational culture types are associated with psychological distress, depression, emotional exhaustion, and well-being. Methods Data were collected over a sample of 1,164 employees nested in 30 workplaces. Employees completed the 26-item OCP instrument. Psychological distress was measured with the General Health Questionnaire (12-item); depression with the Beck Depression Inventory (21-item); and emotional exhaustion with five items from the Maslach Burnout Inventory general survey. Exploratory factor analysis evaluated the dimensionality of the OCP scale. Multilevel regression models estimated workplace-level variations, and the contribution of organizational culture factors to mental health and well-being after controlling for gender, age, and living with a partner. Results Exploratory factor analysis of OCP items revealed four factors explaining about 75% of the variance, and supported the structure of the Competing Values Framework. Factors were labeled Group, Hierarchical, Rational and Developmental. Cronbach’s alphas were high (0.82-0.89). Multilevel regression analysis suggested that the four culture types varied significantly between workplaces, and correlated with mental health and well-being outcomes. The Group culture type best distinguished between workplaces and had the strongest associations with the outcomes. Conclusions This study provides strong support for the use of the OCP scale for measuring organizational culture in population-based occupational health research in a way that is consistent with the Competing Values Framework. The Group organizational culture needs to be considered as a relevant factor in occupational health studies. PMID:23642223

  19. Quantitative analysis of organizational culture in occupational health research: a theory-based validation in 30 workplaces of the organizational culture profile instrument.

    Science.gov (United States)

    Marchand, Alain; Haines, Victor Y; Dextras-Gauthier, Julie

    2013-05-04

    This study advances a measurement approach for the study of organizational culture in population-based occupational health research, and tests how different organizational culture types are associated with psychological distress, depression, emotional exhaustion, and well-being. Data were collected over a sample of 1,164 employees nested in 30 workplaces. Employees completed the 26-item OCP instrument. Psychological distress was measured with the General Health Questionnaire (12-item); depression with the Beck Depression Inventory (21-item); and emotional exhaustion with five items from the Maslach Burnout Inventory general survey. Exploratory factor analysis evaluated the dimensionality of the OCP scale. Multilevel regression models estimated workplace-level variations, and the contribution of organizational culture factors to mental health and well-being after controlling for gender, age, and living with a partner. Exploratory factor analysis of OCP items revealed four factors explaining about 75% of the variance, and supported the structure of the Competing Values Framework. Factors were labeled Group, Hierarchical, Rational and Developmental. Cronbach's alphas were high (0.82-0.89). Multilevel regression analysis suggested that the four culture types varied significantly between workplaces, and correlated with mental health and well-being outcomes. The Group culture type best distinguished between workplaces and had the strongest associations with the outcomes. This study provides strong support for the use of the OCP scale for measuring organizational culture in population-based occupational health research in a way that is consistent with the Competing Values Framework. The Group organizational culture needs to be considered as a relevant factor in occupational health studies.

  20. MRI Brain Tumor Segmentation Methods- A Review

    OpenAIRE

    Gursangeet, Kaur; Jyoti, Rani

    2016-01-01

    Medical image processing and its segmentation is an active and interesting area for researchers. It has reached at the tremendous place in diagnosing tumors after the discovery of CT and MRI. MRI is an useful tool to detect the brain tumor and segmentation is performed to carry out the useful portion from an image. The purpose of this paper is to provide an overview of different image segmentation methods like watershed algorithm, morphological operations, neutrosophic sets, thresholding, K-...

  1. MRI of meningioma

    International Nuclear Information System (INIS)

    Yamamoto, Yoshio; Hiraki, Yoshio; Kaji, Mitumasa

    1988-01-01

    MRI has gained a prominent position in the diagnosis of brain tumors. We examined 30 cases of meningiomas and distinguished their subtype according to the criteria of Rubinic histology. We discussed the MRI findings and compared then with X-CT findings so to their intensity, delination of tumors, whether accompanied by peripheral edema, and T 1 values. MRI delinated the tumors as well as CE-CT. No remarkable difference was found between the subtypes. (author)

  2. TH-A-17A-01: Innovation in PET Instrumentation and Applications

    Energy Technology Data Exchange (ETDEWEB)

    Casey, M [Siemens Healthcare, Knoxville, Tennessee (United States); Miyaoka, R [University of Washington, Seattle, WA (United States); Shao, Y [University of Texas MD Anderson Cancer Center, Houston, TX (United States)

    2014-06-15

    Innovation in PET instrumentation has led to the new millennium revolutionary imaging applications for diagnosis, therapeutic guidance, and development of new molecular imaging probes, etc. However, after several decades innovations, will the advances of PET technology and applications continue with the same trend and pace? What will be the next big thing beyond the PET/CT, PET/MRI, and Time-of-flight PET? How will the PET instrumentation and imaging performance be further improved by novel detector research and advanced imaging system development? Or will the development of new algorithms and methodologies extend the limit of current instrumentation and leapfrog the imaging quality and quantification for practical applications? The objective of this session is to present an overview of current status and advances in the PET instrumentation and applications with speakers from leading academic institutes and a major medical imaging company. Presenting with both academic research projects and commercial technology developments, this session will provide a glimpse of some latest advances and challenges in the field, such as using semiconductor photon-sensor based PET detectors to improve performance and enable new applications, as well as the technology trend that may lead to the next breakthrough in PET imaging for clinical and preclinical applications. Both imaging and image-guided therapy subjects will be discussed. Learning Objectives: Describe the latest innovations in PET instrumentation and applications Understand the driven force behind the PET instrumentation innovation and development Learn the trend of PET technology development for applications.

  3. TH-A-17A-01: Innovation in PET Instrumentation and Applications

    International Nuclear Information System (INIS)

    Casey, M; Miyaoka, R; Shao, Y

    2014-01-01

    Innovation in PET instrumentation has led to the new millennium revolutionary imaging applications for diagnosis, therapeutic guidance, and development of new molecular imaging probes, etc. However, after several decades innovations, will the advances of PET technology and applications continue with the same trend and pace? What will be the next big thing beyond the PET/CT, PET/MRI, and Time-of-flight PET? How will the PET instrumentation and imaging performance be further improved by novel detector research and advanced imaging system development? Or will the development of new algorithms and methodologies extend the limit of current instrumentation and leapfrog the imaging quality and quantification for practical applications? The objective of this session is to present an overview of current status and advances in the PET instrumentation and applications with speakers from leading academic institutes and a major medical imaging company. Presenting with both academic research projects and commercial technology developments, this session will provide a glimpse of some latest advances and challenges in the field, such as using semiconductor photon-sensor based PET detectors to improve performance and enable new applications, as well as the technology trend that may lead to the next breakthrough in PET imaging for clinical and preclinical applications. Both imaging and image-guided therapy subjects will be discussed. Learning Objectives: Describe the latest innovations in PET instrumentation and applications Understand the driven force behind the PET instrumentation innovation and development Learn the trend of PET technology development for applications

  4. MRI assessment program

    International Nuclear Information System (INIS)

    1988-05-01

    Usage, cost and efficacy data from the MRI Assessment Program to 30 March 1988 is presented, as a continuation of an earlier analysis. Analysis has been performed on data from 8565 examinations relating to 7997 patients at 4 hospitals. MRI was used mainly for examination of the head and spine. Some details of the follow up studies being conducted on selected patients and disease categories are given. A consensus statement is included which summaries the view of the Technical Committee on the potential applications of MRI in Australia. The MRI unit quench incident at Royal Adelaide Hospital is described. Refs., 10 figs., tabs

  5. Report of the second research co-ordination meeting on the co-ordinated research programme: rapid instrumental and separation methods for monitoring radionuclides in food and environmental samples

    International Nuclear Information System (INIS)

    1992-10-01

    The purpose of this Second Research Co-ordinated Meeting (12-16 August 1991) on Rapid Instrumental and Separation Methods for Monitoring Radionuclides in Food and Environmental Samples is to discuss the progress of the programmes since the First Research Co-ordination Meeting, discuss how to validate the methodologies developed (e.g. reference samples, intercomparisons), and outline a schedule for CRP completion by the end of 1992. Radioactive contamination of the environment after a nuclear accident, such as had occurred at Chernobyl, is of serious concern to government officials and members of the general public. In 1990/1991 the Agency was asked to organize the International Chernobyl Project to assess the situation in the USSR. A network of laboratories was organized to carry out the environmental assessment needed for this project. The following recommendations are based on the experience gained by many of the laboratories involved in this project. 1. Maintain a network of analytical laboratories with special skills and experience to provide assessments of radionuclide contamination in the environment in case of a radiological emergency. 2. Methodologies for assessment of contamination in the environment should take into consideration potential trajectories, radioecology, and food chain parameters. 3. Focus on areas of representative sample collection, is situ instrumental and chemical analysis, as well as advanced streamlined laboratory analyses which will facilitate the timeline of an assessment. 4. Conduct intercomparison and testing of technologies, employing standard reference materials and procedures, and field measurements at significantly contaminated area. 5. Conduct training of Member State laboratory personnel through fellowships, special courses, and workshops. 5 refs

  6. WE-EF-BRD-01: Past, Present and Future: MRI-Guided Radiotherapy From 2005 to 2025

    Energy Technology Data Exchange (ETDEWEB)

    Lagendijk, J. [University Medical Center Utrecht (Netherlands)

    2015-06-15

    MRI-guided treatment is a growing area of medicine, particularly in radiotherapy and surgery. The exquisite soft tissue anatomic contrast offered by MRI, along with functional imaging, makes the use of MRI during therapeutic procedures very attractive. Challenging the utility of MRI in the therapy room are many issues including the physics of MRI and the impact on the environment and therapeutic instruments, the impact of the room and instruments on the MRI; safety, space, design and cost. In this session, the applications and challenges of MRI-guided treatment will be described. The session format is: Past, present and future: MRI-guided radiotherapy from 2005 to 2025: Jan Lagendijk Battling Maxwell’s equations: Physics challenges and solutions for hybrid MRI systems: Paul Keall I want it now!: Advances in MRI acquisition, reconstruction and the use of priors to enable fast anatomic and physiologic imaging to inform guidance and adaptation decisions: Yanle Hu MR in the OR: The growth and applications of MRI for interventional radiology and surgery: Rebecca Fahrig Learning Objectives: To understand the history and trajectory of MRI-guided radiotherapy To understand the challenges of integrating MR imaging systems with linear accelerators To understand the latest in fast MRI methods to enable the visualisation of anatomy and physiology on radiotherapy treatment timescales To understand the growing role and challenges of MRI for image-guided surgical procedures My disclosures are publicly available and updated at: http://sydney.edu.au/medicine/radiation-physics/about-us/disclosures.php.

  7. WE-EF-BRD-04: MR in the OR: The Growth and Applications of MRI for Interventional Radiology and Surgery

    Energy Technology Data Exchange (ETDEWEB)

    Fahrig, R. [Stanford University (United States)

    2015-06-15

    MRI-guided treatment is a growing area of medicine, particularly in radiotherapy and surgery. The exquisite soft tissue anatomic contrast offered by MRI, along with functional imaging, makes the use of MRI during therapeutic procedures very attractive. Challenging the utility of MRI in the therapy room are many issues including the physics of MRI and the impact on the environment and therapeutic instruments, the impact of the room and instruments on the MRI; safety, space, design and cost. In this session, the applications and challenges of MRI-guided treatment will be described. The session format is: Past, present and future: MRI-guided radiotherapy from 2005 to 2025: Jan Lagendijk Battling Maxwell’s equations: Physics challenges and solutions for hybrid MRI systems: Paul Keall I want it now!: Advances in MRI acquisition, reconstruction and the use of priors to enable fast anatomic and physiologic imaging to inform guidance and adaptation decisions: Yanle Hu MR in the OR: The growth and applications of MRI for interventional radiology and surgery: Rebecca Fahrig Learning Objectives: To understand the history and trajectory of MRI-guided radiotherapy To understand the challenges of integrating MR imaging systems with linear accelerators To understand the latest in fast MRI methods to enable the visualisation of anatomy and physiology on radiotherapy treatment timescales To understand the growing role and challenges of MRI for image-guided surgical procedures My disclosures are publicly available and updated at: http://sydney.edu.au/medicine/radiation-physics/about-us/disclosures.php.

  8. WE-EF-BRD-02: Battling Maxwell’s Equations: Physics Challenges and Solutions for Hybrid MRI Systems

    Energy Technology Data Exchange (ETDEWEB)

    Keall, P. [University of Sydney (Australia)

    2015-06-15

    MRI-guided treatment is a growing area of medicine, particularly in radiotherapy and surgery. The exquisite soft tissue anatomic contrast offered by MRI, along with functional imaging, makes the use of MRI during therapeutic procedures very attractive. Challenging the utility of MRI in the therapy room are many issues including the physics of MRI and the impact on the environment and therapeutic instruments, the impact of the room and instruments on the MRI; safety, space, design and cost. In this session, the applications and challenges of MRI-guided treatment will be described. The session format is: Past, present and future: MRI-guided radiotherapy from 2005 to 2025: Jan Lagendijk Battling Maxwell’s equations: Physics challenges and solutions for hybrid MRI systems: Paul Keall I want it now!: Advances in MRI acquisition, reconstruction and the use of priors to enable fast anatomic and physiologic imaging to inform guidance and adaptation decisions: Yanle Hu MR in the OR: The growth and applications of MRI for interventional radiology and surgery: Rebecca Fahrig Learning Objectives: To understand the history and trajectory of MRI-guided radiotherapy To understand the challenges of integrating MR imaging systems with linear accelerators To understand the latest in fast MRI methods to enable the visualisation of anatomy and physiology on radiotherapy treatment timescales To understand the growing role and challenges of MRI for image-guided surgical procedures My disclosures are publicly available and updated at: http://sydney.edu.au/medicine/radiation-physics/about-us/disclosures.php.

  9. WE-EF-BRD-02: Battling Maxwell’s Equations: Physics Challenges and Solutions for Hybrid MRI Systems

    International Nuclear Information System (INIS)

    Keall, P.

    2015-01-01

    MRI-guided treatment is a growing area of medicine, particularly in radiotherapy and surgery. The exquisite soft tissue anatomic contrast offered by MRI, along with functional imaging, makes the use of MRI during therapeutic procedures very attractive. Challenging the utility of MRI in the therapy room are many issues including the physics of MRI and the impact on the environment and therapeutic instruments, the impact of the room and instruments on the MRI; safety, space, design and cost. In this session, the applications and challenges of MRI-guided treatment will be described. The session format is: Past, present and future: MRI-guided radiotherapy from 2005 to 2025: Jan Lagendijk Battling Maxwell’s equations: Physics challenges and solutions for hybrid MRI systems: Paul Keall I want it now!: Advances in MRI acquisition, reconstruction and the use of priors to enable fast anatomic and physiologic imaging to inform guidance and adaptation decisions: Yanle Hu MR in the OR: The growth and applications of MRI for interventional radiology and surgery: Rebecca Fahrig Learning Objectives: To understand the history and trajectory of MRI-guided radiotherapy To understand the challenges of integrating MR imaging systems with linear accelerators To understand the latest in fast MRI methods to enable the visualisation of anatomy and physiology on radiotherapy treatment timescales To understand the growing role and challenges of MRI for image-guided surgical procedures My disclosures are publicly available and updated at: http://sydney.edu.au/medicine/radiation-physics/about-us/disclosures.php

  10. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... or patients with claustrophobia. Other MRI machines are open on the sides (open MRI). Open units are especially helpful for examining larger patients or those with claustrophobia. Newer open MRI units provide very high quality images for ...

  11. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... does not completely surround you. Some newer MRI machines have a larger diameter bore which can be ... size patients or patients with claustrophobia. Other MRI machines are open on the sides (open MRI). Open ...

  12. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... in the first three to four months of pregnancy unless the potential benefit from the MRI exam ... the MRI Safety page for more information about pregnancy and MRI. If you have claustrophobia (fear of ...

  13. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... information on the chemicals present in the body's cells, may also be performed during the MRI exam ... medically necessary. MRI may not always distinguish between cancer tissue and fluid, known as edema . MRI typically ...

  14. Post-mortem MRI as an alternative to non-forensic autopsy in foetuses and children: from research into clinical practice

    Science.gov (United States)

    Addison, S; Arthurs, O J

    2014-01-01

    Although post-mortem MRI (PMMR) was proposed as an alternative to conventional autopsy more than a decade ago, the lack of systematic validation has limited its clinical uptake. Minimally invasive autopsy (MIA) using PMMR together with ancillary investigations has now been shown to be as accurate as conventional autopsy in foetuses, newborns and infants and is particularly useful for cerebral, cardiac and genitourinary imaging. Unlike conventional autopsy, PMMR provides a permanent three-dimensional auditable record, with accurate estimation of internal organ volumes. MIA is becoming highly acceptable to parents and professionals, and there is widespread political support and public interest in its clinical implementation in the UK. In the short to medium term, it is desirable that a supraregional network of specialist centres should be established to provide this service within the current National Health Service framework. PMID:24288400

  15. A systematic critical appraisal for non-pharmacological management of osteoarthritis using the appraisal of guidelines research and evaluation II instrument.

    Science.gov (United States)

    Brosseau, Lucie; Rahman, Prinon; Toupin-April, Karine; Poitras, Stéphane; King, Judy; De Angelis, Gino; Loew, Laurianne; Casimiro, Lynn; Paterson, Gail; McEwan, Jessica

    2014-01-01

    Clinical practice CPGs (CPGs) have been developed to summarize evidence related to the management of osteoarthritis (OA). CPGs facilitate uptake of evidence-based knowledge by consumers, health professionals, health administrators and policy makers. The objectives of the present review were: 1) to assess the quality of the CPGs on non-pharmacological management of OA; using a standardized and validated instrument--the Appraisal of Guidelines Research and Evaluation (AGREE II) tool--by three pairs of trained appraisers; and 2) to summarize the recommendations based on only high-quality existing CPGs. Scientific literature databases from 2001 to 2013 were systematically searched for the state of evidence, with 17 CPGs for OA being identified. Most CPGs effectively addressed only a minority of AGREE II domains. Scope and purpose was effectively addressed in 10 CPGs on the management of OA, stakeholder involvement in 12 CPGs, rigour of development in 10 CPGs, clarity/presentation in 17 CPGs, editorial independence in 2 CPGs, and applicability in none of the OA CPGs. The overall quality of the included CPGs, according to the 7-point AGREE II scoring system, is 4.8 ± 0.41 for OA. Therapeutic exercises, patient education, transcutaneous electrical nerve stimulation, acupuncture, orthoses and insoles, heat and cryotherapy, patellar tapping, and weight control are commonly recommended for the non-pharmacological management of OA by the high-quality CPGs. The general clinical management recommendations tended to be similar among high-quality CPGs, although interventions addressed varied. Non-pharmacological management interventions were superficially addressed in more than half of the selected CPGs. For CPGs to be standardized uniform creators should use the AGREE II criteria when developing CPGs. Innovative and effective methods of CPG implementation to users are needed to ultimately enhance the quality of life of arthritic individuals.

  16. Research on the Design of Automatic Instrument in Chemical Industry%化工企业中自动化仪表的设计探究

    Institute of Scientific and Technical Information of China (English)

    鞠伟亚

    2015-01-01

    The production and operation environment of chemical enterprises is high pressure, high temperature, vacuum and other special environment, but in this special environment, automatic instrument plays a very important role. Therefore, we must do a good job in the design of chemical enterprise automation instrument; improve the stability and reliability of the automation instrument. Through the analysis of common chemical enterprise automatic instrument classification and instrument design selection, this paper describes the chemical enterprise automation instrument design technology, for reference.%化工企业的生产运营环境多是高压、高温、真空等特殊环境,而在这种特殊环境中,自动化仪表发挥着非常重要的作用.因此,必须做好化工企业的自动化仪表设计工作,提高自动化仪表的稳定性和可靠性.通过分析常见的化工企业自动化仪表分类和仪表设计选型,阐述了化工企业自动化仪表设计技术,以供参考.

  17. Seismic instrumentation

    International Nuclear Information System (INIS)

    1984-06-01

    RFS or Regles Fondamentales de Surete (Basic Safety Rules) applicable to certain types of nuclear facilities lay down requirements with which compliance, for the type of facilities and within the scope of application covered by the RFS, is considered to be equivalent to compliance with technical French regulatory practice. The object of the RFS is to take advantage of standardization in the field of safety, while allowing for technical progress in that field. They are designed to enable the operating utility and contractors to know the rules pertaining to various subjects which are considered to be acceptable by the Service Central de Surete des Installations Nucleaires, or the SCSIN (Central Department for the Safety of Nuclear Facilities). These RFS should make safety analysis easier and lead to better understanding between experts and individuals concerned with the problems of nuclear safety. The SCSIN reserves the right to modify, when considered necessary, any RFS and specify, if need be, the terms under which a modification is deemed retroactive. The aim of this RFS is to define the type, location and operating conditions for seismic instrumentation needed to determine promptly the seismic response of nuclear power plants features important to safety to permit comparison of such response with that used as the design basis

  18. Meteorological instrumentation

    International Nuclear Information System (INIS)

    1982-06-01

    RFS or ''Regles Fondamentales de Surete'' (Basic Safety Rules) applicable to certain types of nuclear facilities lay down requirements with which compliance, for the type of facilities and within the scope of application covered by the RFS, is considered to be equivalent to compliance with technical French regulatory practice. The object of the RFS is to take advantage of standardization in the field of safety , while allowing for technical progress in that field. They are designed to enable the operating utility and contractors to know the rules pertaining to various subjects which are considered to be acceptable by the ''Service Central de Surete des Installations Nucleaires'' or the SCSIN (Central Department for the Safety of Nuclear Facilities). These RFS should make safety analysis easier and lead to better understanding between experts and individuals concerned with the problems of nuclear safety. The SCSIN reserves the right to modify, when considered necessary any RFS and specify, if need be, the terms under which a modification is deemed retroactive. The purpose of this RFS is to specify the meteorological instrumentation required at the site of each nuclear power plant equipped with at least one pressurized water reactor

  19. MRI in sarcoglycanopathies

    DEFF Research Database (Denmark)

    Tasca, Giorgio; Monforte, Mauro; Díaz-Manera, Jordi

    2018-01-01

    OBJECTIVES: To characterise the pattern and spectrum of involvement on muscle MRI in a large cohort of patients with sarcoglycanopathies, which are limb-girdle muscular dystrophies (LGMD2C-2F) caused by mutations in one of the four genes coding for muscle sarcoglycans. METHODS: Lower limb MRI sca...

  20. MRI of the Chest

    Medline Plus

    Full Text Available ... Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info About Us News Physician ... absolutely necessary for medical treatment. See the MRI Safety page for more information about pregnancy and MRI. ...

  1. MRI of the Chest

    Medline Plus

    Full Text Available ... internal body structures. MRI does not use ionizing radiation (x-rays). Detailed MR images allow physicians to evaluate various ... seen by other imaging modalities, such as chest x-ray or CT. A special form of MRI called ...

  2. MRI of the Chest

    Medline Plus

    Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos About Us News Physician ... Magnetic resonance imaging (MRI) is a noninvasive medical test that physicians use to diagnose medical conditions. MRI ...

  3. MRI of the Chest

    Medline Plus

    Full Text Available ... fitting and has no metal fasteners. Guidelines about eating and drinking before an MRI exam vary with the specific exam and with the imaging facility. Unless you are told otherwise, you may follow your regular daily routine and take food and medications as usual. Some MRI examinations may ...

  4. MRI of the Chest

    Medline Plus

    Full Text Available ... metallic items, which can distort MRI images removable dental work pens, pocket knives and eyeglasses body piercings In most cases, an MRI exam is safe for patients with metal implants, except for a few types. People with the ...

  5. MRI of neonatal encephalopathy

    International Nuclear Information System (INIS)

    Khong, P.L.; Lam, B.C.C.; Tung, H.K.S.; Wong, V.; Chan, F.L.; Ooi, G.C.

    2003-01-01

    We present the magnetic resonance imaging (MRI) findings in neonatal encephalopathy, including hypoxic-ischaemic encephalopathy, perinatal/neonatal stroke, metabolic encephalopathy from inborn errors of metabolism, congenital central nervous system infections and birth trauma. The applications of advanced MRI techniques, such as diffusion-weighted imaging and magnetic resonance spectroscopy are emphasized

  6. MRI of the Chest

    Medline Plus

    Full Text Available ... body structures. MRI does not use ionizing radiation (x-rays). Detailed MR images allow physicians to evaluate various ... seen by other imaging modalities, such as chest x-ray or CT. A special form of MRI called ...

  7. MRI of the Chest

    Medline Plus

    Full Text Available ... structure of an organ and how it is working. MRI enables the discovery of abnormalities that might be obscured by bone with other imaging methods. The contrast material used in MRI exams is less likely to produce an allergic reaction than the ...

  8. MRI of the Chest

    Medline Plus

    Full Text Available ... computer to produce detailed pictures of organs, soft tissues, bone and virtually all other internal body structures. MRI ... cancer, heart and vascular disease, heart valve abnormalities, bone and other soft tissue abnormalities of the chest. MRI is also useful ...

  9. MRI of the Chest

    Medline Plus

    Full Text Available ... other internal body structures. MRI does not use ionizing radiation (x-rays). Detailed MR images allow physicians to ... computed tomography (CT) scans, MRI does not utilize ionizing radiation. Instead, radiofrequency pulses re-align hydrogen atoms that ...

  10. MRI of the Chest

    Medline Plus

    Full Text Available ... Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos About Us ... absolutely necessary for medical treatment. See the MRI Safety page for more information about pregnancy and MRI. ...

  11. ACRF Instrumentation Status: New, Current, and Future January 2007

    Energy Technology Data Exchange (ETDEWEB)

    Liljegren, JC

    2007-01-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Program Climate Research Facility instrumentation status. The report is divided into four sections: (1) new instrumentation in the process of being acquired and deployed, (2) existing instrumentation and progress on improvements or upgrades, (3) proposed future instrumentation, and (4) Small Business Innovation Research instrument development.

  12. ACRF Instrumentation Status: New, Current, and Future October 2006

    Energy Technology Data Exchange (ETDEWEB)

    JC Liljegren

    2006-10-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Program Climate Research Facility instrumentation status. The report is divided into four sections: (1) new instrumentation in the process of being acquired and deployed, (2) existing instrumentation and progress on improvements or upgrades, (3) proposed future instrumentation, and (4) Small Business Innovation Research instrument development.

  13. ACRF Instrumentation Status: New, Current, and Future May 2007

    Energy Technology Data Exchange (ETDEWEB)

    JC Liljegren

    2007-05-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Program Climate Research Facility instrumentation status. The report is divided into four sections: (1) new instrumentation in the process of being acquired and deployed, (2) existing instrumentation and progress on improvements or upgrades, (3) proposed future instrumentation, and (4) Small Business Innovation Research instrument development.

  14. ACRF Instrumentation Status: New, Current, and Future February 2007

    Energy Technology Data Exchange (ETDEWEB)

    JC Liljegren

    2007-02-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Program Climate Research Facility instrumentation status. The report is divided into four sections: (1) new instrumentation in the process of being acquired and deployed, (2) existing instrumentation and progress on improvements or upgrades, (3) proposed future instrumentation, and (4) Small Business Innovation Research instrument development

  15. ACRF Instrumentation Status: New, Current, and Future May 2007

    Energy Technology Data Exchange (ETDEWEB)

    JC Liljegren

    2007-04-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Program Climate Research Facility instrumentation status. The report is divided into four sections: (1) new instrumentation in the process of being acquired and deployed, (2) existing instrumentation and progress on improvements or upgrades, (3) proposed future instrumentation, and (4) Small Business Innovation Research instrument development.

  16. ACRF Instrumentation Status: New, Current, and Future March 2007

    Energy Technology Data Exchange (ETDEWEB)

    JC Liljegren

    2007-03-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Program Climate Research Facility instrumentation status. The report is divided into four sections: (1) new instrumentation in the process of being acquired and deployed, (2) existing instrumentation and progress on improvements or upgrades, (3) proposed future instrumentation, and (4) Small Business Innovation Research instrument development.

  17. ACRF Instrumentation Status: New, Current, and Future - February 2008

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2008-03-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following four sections: (1) new instrumentation in the process of being acquired and deployed, (2) existing instrumentation and progress on improvements or upgrades, (3) proposed future instrumentation, and (4) Small Business Innovation Research instrument development.

  18. ACRF Instrumentation Status: New, Current, and Future - March 2008

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2008-04-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following four sections: (1) new instrumentation in the process of being acquired and deployed, (2) existing instrumentation and progress on improvements or upgrades, (3) proposed future instrumentation, and (4) Small Business Innovation Research instrument development.

  19. Advanced Instrumentation, Information and Control (II&C) Research and Development Facility Buildout and Project Execution of LWRS II&C Pilot Projects 1 and 3

    Energy Technology Data Exchange (ETDEWEB)

    Ronald Farris; Johanna Oxstrand; Gregory Weatherby

    2011-09-01

    The U.S. Department of Energy (DOE) is sponsoring research, development, and deployment on light water reactor sustainability (LWRS), in which the Idaho National Laboratory (INL) is working closely with nuclear utilities to develop technologies and solutions to help ensure the safe operational life extension of current reactors. As technologies are introduced that change the operation of the plant, the LWRS pilot projects can help identify their best-advanced uses and help demonstrate the safety of these technologies. In early testing of operator performance given these emerging technologies will ensure the safety and usability of systems prior to large-scale deployment and costly verification and validation at the plant. The aim of these collaborations, demonstrations, and approaches are intended to lessen the inertia that sustains the current status quo of today's II&C systems technology, and to motivate transformational change and a shift in strategy to a long-term approach to II&C modernization that is more sustainable. Research being conducted under Pilot Project 1 regards understanding the conditions and behaviors that can be modified, either through process improvements and/or technology deployment, to improve the overall safety and efficiency of outage control at nuclear facilities. The key component of the research in this pilot project is accessing the delivery of information that will allow researchers to simulate the control room, outage control center (OCC) information, and plant status data. The simulation also allows researchers to identify areas of opportunity where plant operating status and outage activities can be analyzed to increase overall plant efficiency. For Pilot Project 3 the desire is to demonstrate the ability of technology deployment and the subsequent impact on maximizing the 'Collective Situational Awareness' of the various stakeholders in a commercial nuclear power plant. Specifically, the desire is to show positive

  20. Advanced Instrumentation, Information and Control (II and C) Research and Development Facility Buildout and Project Execution of LWRS II and C Pilot Projects 1 and 3

    International Nuclear Information System (INIS)

    Farris, Ronald; Oxstrand, Johanna; Weatherby, Gregory

    2011-01-01

    The U.S. Department of Energy (DOE) is sponsoring research, development, and deployment on light water reactor sustainability (LWRS), in which the Idaho National Laboratory (INL) is working closely with nuclear utilities to develop technologies and solutions to help ensure the safe operational life extension of current reactors. As technologies are introduced that change the operation of the plant, the LWRS pilot projects can help identify their best-advanced uses and help demonstrate the safety of these technologies. In early testing of operator performance given these emerging technologies will ensure the safety and usability of systems prior to large-scale deployment and costly verification and validation at the plant. The aim of these collaborations, demonstrations, and approaches are intended to lessen the inertia that sustains the current status quo of today's II and C systems technology, and to motivate transformational change and a shift in strategy to a long-term approach to II and C modernization that is more sustainable. Research being conducted under Pilot Project 1 regards understanding the conditions and behaviors that can be modified, either through process improvements and/or technology deployment, to improve the overall safety and efficiency of outage control at nuclear facilities. The key component of the research in this pilot project is accessing the delivery of information that will allow researchers to simulate the control room, outage control center (OCC) information, and plant status data. The simulation also allows researchers to identify areas of opportunity where plant operating status and outage activities can be analyzed to increase overall plant efficiency. For Pilot Project 3 the desire is to demonstrate the ability of technology deployment and the subsequent impact on maximizing the 'Collective Situational Awareness' of the various stakeholders in a commercial nuclear power plant. Specifically, the desire is to show positive results