WorldWideScience

Sample records for research focus estimates

  1. Doing focus group research

    DEFF Research Database (Denmark)

    Lindegaard, Laura Bang

    2014-01-01

    Scholars of ethnomethodologically informed discourse studies are often sceptical of the use of interview data such as focus group data. Some scholars quite simply reject interview data with reference to a general preference for so-called naturally occurring data. Other scholars acknowledge...... that interview data can be of some use if the distinction between natural and contrived data is given up and replaced with a distinction between interview data as topic or as resource. In greater detail, such scholars argue that interview data are perfectly adequate if the researcher wants to study the topic...... of interview interaction, but inadequate as data for studying phenomena that go beyond the phenomenon of interview interaction. Neither of these more and less sceptical positions are, on the face of it, surprising due to the ethnomethodological commitment to study social order as accomplished in situ...

  2. Focus on International Cooperation in D and D Cost Estimations for Research Reactors and the Role of the IAEA in It

    International Nuclear Information System (INIS)

    Daniska, V.; Laraia, M.

    2009-01-01

    Estimating decommissioning costs and collecting funds are the prerequisites for safe, timely and cost effective decommissioning. These issues were addressed by main international organizations involved in decommissioning - IAEA, OECD/NEA and European Commission. While the activities of OECD/NEA and European Commission are focused mainly on nuclear power plants, the activities of IAEA involve the whole spectrum of nuclear facilities worldwide and the aspects of decommissioning of research reactors, due to their spread in member states, have the special position in IAEA activities. The experience in decommissioning of research reactors was accumulated in developed countries and international activities are needed to support the planning and implementation of decommissioning of research reactors in other IAEA Member States. Decommissioning costing plays the key role among these issues. One of the main results of the common effort of the above listed organisations in costing is the standardised structure of decommissioning cost items which was jointly published as the common platform for harmonisation in decommissioning costing and is recommended for general use. Main subject of the paper is the preliminary presentation of a new IAEA project planned for the period 2009-2011 with the objectives to develop the robust standardised cost estimation methodology, which implements the standardised cost structure. The aim of the proposed methodology is to support the Member States to prepare their own specific cost estimates for research reactors. The planned target is the parametric cost estimating model applicable for various types of research reactors and for various national decommissioning backgrounds. The model is supported by facility inventory database and database of unit factors and data specific for facility to be decommissioned. The paper reviews main types of research reactors; the currant practice for decommissioning costing which will be implemented in the

  3. Focus groups in organizational research

    Directory of Open Access Journals (Sweden)

    L. Kamfer

    1989-05-01

    Full Text Available Focus groups are commonly used in marketing research. In this article an application of the focus group technique within an organizational context is described. Nine focus groups were conducted during the planning stage of a survey intended to establish employee perceptions of advancement policies and practices in a major South African manufacturing company. Fourteen themes emerged from a content analysis of the discussions. Two of these reflected aspects requiring commitment decisions from management toward the survey. The others indicated areas of concern which should be included in the survey. In this way, the focus groups contributed useful information for the subsequent sample survey. Opsomming Fokusgroepe word algemeen in bemarkingsnavorsing aangewend. In hierdie studie word 'n toepassingvan die fokusgroeptegniek in die konteks van 'n opname binne 'n organisasie beskryf. Nege fokusgroepbesprekings is gevoer tydens die beplanningstadium van 'n opname wat binne 'n Suid-Afrikaanse vervaardigingsonderneming gedoen is. Die doel van die opname was om die persepsies van werknemers teenoor die bestaande personeel- en bestuursontwikkelingsbeleid en -praktyke van die maatskappy te bepaal. Veertien temas is deur middel van 'n inhoudontleding gei'dentifiseer. Twee hiervan het aspekte aangedui waaroor bestuur beginselbesluite t.o.v. die opname sou moes neem. Die ander het probleemareas aangedui wat by die ondersoek selfingesluit behoort te word. Sodoende het die fokusgroepe inligting verskafwat vir die latere vraelysopname belangrik was.

  4. Focus on nuclear fusion research

    Czech Academy of Sciences Publication Activity Database

    Křenek, Petr; Mlynář, Jan

    2011-01-01

    Roč. 61, - (2011), s. 62-63 ISSN 0375-8842 Institutional research plan: CEZ:AV0Z20430508 Keywords : ITER * COMPASS * fusion energy * tokamak * EURATOM Subject RIV: BL - Plasma and Gas Discharge Physics http://www.ipp.cas.cz/Tokamak/clanky/energetika_COMPASS.pdf

  5. BIOENERGIA - Focus on wood in bioenergy research

    Energy Technology Data Exchange (ETDEWEB)

    Asplund, D. [Jyvaeskylae Science Park, Jyvaeskylae (Finland)

    1996-12-31

    The most important area of research on wood fuel production is the development of various methods, machines and systems connected to this area, in order to produce economically competitive fuels. The integrated harvesting methods, which supply both raw material to wood products industry and wood fuel for energy production, have been chosen the main research area because they seem to be most promising. The growing amount of small-sized trees ant the need of their first thinnings have created a demand for new harvesting methods. At the moment the economical aspects restrict the harvesting of the first thinning trees either for industrial use or energy production. Research on peat production focuses on the complete use of a bog and on the development of peat production methods and machines. Development work in this area aims at decreasing production costs and also at reducing the drainage water and other elements in environmental load around the peat production sites. The use of bioenergy research will be focused on the small-scale (<20 MW{sub th},) applications. In the long term, the increase of bioenergy in heating of small houses and farms and buildings, as well as in the production of heat and power has been estimated. Research into the conversion of biomass is concentrated on the production of biomass-based liquid fuels

  6. Using Focus Group Research in Public Relations.

    Science.gov (United States)

    Grunig, Larissa A.

    1990-01-01

    Analyzes a recent instance of focus group research applied to a public relations case (rather than a marketing case). Reviews the advantages and disadvantages of this qualitative method, and describes the case of a county department of mental health relying on focus group research to help plan a program aimed at reducing the stigma of mental…

  7. An improved estimation and focusing scheme for vector velocity estimation

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt; Munk, Peter

    1999-01-01

    to reduce spatial velocity dispersion. Examples of different velocity vector conditions are shown using the Field II simulation program. A relative accuracy of 10.1 % is obtained for the lateral velocity estimates for a parabolic velocity profile for a flow perpendicular to the ultrasound beam and a signal...

  8. Virtual Focus Groups: New Frontiers in Research

    Directory of Open Access Journals (Sweden)

    Lyn Turney

    2005-06-01

    Full Text Available New information and communication technologies in the form of learning management systems provide unique and inventive opportunities for qualitative researchers. Their intrinsic ability to record discursive data in text format accurately and to provide safe, secure, and anonymous environments for participants makes them amenable for use as advanced research tools. In this article, the authors report on a collaborative project that tested the potential of online discussion boards for use in virtual focus groups. What the researchers found was that not only was the method theoretically sound, it actually enhanced their ability to connect with difficult-to-access populations that were disparately spread.

  9. Fast focus estimation using frequency analysis in digital holography.

    Science.gov (United States)

    Oh, Seungtaik; Hwang, Chi-Young; Jeong, Il Kwon; Lee, Sung-Keun; Park, Jae-Hyeung

    2014-11-17

    A novel fast frequency-based method to estimate the focus distance of digital hologram for a single object is proposed. The focus distance is computed by analyzing the distribution of intersections of smoothed-rays. The smoothed-rays are determined by the directions of energy flow which are computed from local spatial frequency spectrum based on the windowed Fourier transform. So our method uses only the intrinsic frequency information of the optical field on the hologram and therefore does not require any sequential numerical reconstructions and focus detection techniques of conventional photography, both of which are the essential parts in previous methods. To show the effectiveness of our method, numerical results and analysis are presented as well.

  10. Cost estimation for decommissioning of research reactors

    International Nuclear Information System (INIS)

    Grossi, Pablo Andrade; Tello, Cledola Cassia Oliveira de; Segabinaze, Roberto de Oliveira; Daniska, Vladimir

    2013-01-01

    In the case of research reactors, the limited data that is available tends to provide only overall decommissioning costs, without any breakdown of the main cost elements. In order to address this subject, it is important to collect and analyse all available data of decommissioning costs for the research reactors. The IAEA has started the DACCORD Project focused on data analysis and costing of research reactors decommissioning. Data collection is organized in accordance with the International Structure for Decommissioning Costing (ISDC), developed jointly by the IAEA, the OECD Nuclear Energy Agency and the European Commission. The specific aims of the project include the development of representative and comparative data and datasets for preliminary costing for decommissioning. This paper will focus on presenting a technique to consider several representative input data in accordance with the ISDC structure and using the CERREX (Cost Estimation for Research Reactors in Excel) software developed by IAEA. (author)

  11. Auditing as Institutional Research: A Qualitative Focus.

    Science.gov (United States)

    Fetterman, David M.

    1991-01-01

    Internal institutional auditing can improve effectiveness and efficiency and protect an institution's assets. Many of the concepts and techniques used to analyze higher education institutions are qualitative in nature and suited to institutional research, including fiscal, operational, data-processing, investigative, management consulting,…

  12. Focus on uranium research in Senegal

    International Nuclear Information System (INIS)

    Kanoute, M.

    2014-01-01

    Two periods stand out in the history of mining exploration for uranium in Senegal: • 1957 - 1965 in the context of a general inventory of the uranium potential of Africa, which is also the time that the large deposits of Niger and Gabon were discovered; • 1973 to the present, is characterized by surveys more focused on specific topics such as Birrimian Superior Precambrian Sedimentary, Secondary and Tertiary Phosphates. The collapse of uranium price that began since 1980 calls into question the validity of these surveys on areas away from the coast that lack infrastructure and forces the elimination of targets where there is little hope of finding high enough concentrations of uranium for possible mining.

  13. 21 CFR 312.86 - Focused FDA regulatory research.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Focused FDA regulatory research. 312.86 Section 312.86 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... Severely-debilitating Illnesses § 312.86 Focused FDA regulatory research. At the discretion of the agency...

  14. Focus on Basics: Connecting Research & Practice. Volume 7, Issue D

    Science.gov (United States)

    Garner, Barbara, Ed.

    2005-01-01

    "Focus on Basics" is the quarterly publication of the National Center for the Study of Adult Learning and Literacy. It presents best practices, current research on adult learning and literacy, and how research is used by adult basic education teachers, counselors, program administrators, and policymakers. "Focus on Basics" is…

  15. Focus Group in Community Mental Health Research: Need for Adaption.

    Science.gov (United States)

    Zupančič, Vesna; Pahor, Majda; Kogovšek, Tina

    2018-04-27

    The article presents an analysis of the use of focus groups in researching community mental health users, starting with the reasons for using them, their implementation in mental health service users' research, and the adaptations of focus group use when researching the experiences of users. Based on personal research experience and a review of scientific publications in the Google Scholar, Web of Science, ProQuest, EBSCOhost, and Scopus databases, 20 articles published between 2010 and 2016 were selected for targeted content analysis. A checklist for reporting on the use of focus groups with community mental health service users, aiming to improve the comparability, verifiability and validity was developed. Adaptations of the implementation of focus groups in relation to participants' characteristics were suggested. Focus groups are not only useful as a scientific research technique, but also for ensuring service users' participation in decision-making in community mental health and evaluating the quality of the mental health system and services .

  16. Reengineering Clinical Research Science: A Focus on Translational Research

    Science.gov (United States)

    Ferrell, Courtney B.

    2009-01-01

    The burden of disease in the United States is high. Mental illness is currently the leading cause of disease burden among 15- to 44-year-olds. This phenomenon is occurring despite the many advances that have been made in clinical research. Several efficacious interventions are available to treat many of these disorders; however, they are greatly…

  17. The use of focused ethnography in nursing research.

    Science.gov (United States)

    Cruz, Edward Venzon; Higginbottom, Gina

    2013-03-01

    To provide an overview of the relevance and strengths of focused ethnography in nursing research. The paper provides descriptions of focused ethnography and discusses using exemplars to show how focused ethnographies can enhance and understand nursing practice. Orthodox ethnographic approaches may not always be suitable or desirable for research in diverse nursing contexts. Focused ethnography has emerged as a promising method for applying ethnography to a distinct issue or shared experience in cultures or sub-cultures and in specific settings, rather than throughout entire communities. Unfortunately, there is limited guidance on using focused ethnography, particularly as applied to nursing research. Research studies performed by nurses using focused ethnography are summarised to show how they fulfilled three main purposes of the genre in nursing research. Additional citations are provided to help demonstrate the versatility of focused ethnography in exploring distinct problems in a specific context in different populations and groups of people. The unique role that nurses play in health care, coupled with their skills in enquiry, can contribute to the further development of the discipline. Focused ethnography offers an opportunity to gain a better understanding and appreciation of nursing as a profession, and the role it plays in society. Focused ethnography has emerged as a relevant research methodology that can be used by nurse researchers to understand specific societal issues that affect different facets of nursing practice. As nurse researchers endeavour to understand experiences in light of their health and life situations, focused ethnography enables them to understand the interrelationship between people and their environments in the society in which they live.

  18. Research Timeline: Form-Focused Instruction and Second Language Acquisition

    Science.gov (United States)

    Nassaji, Hossein

    2016-01-01

    This article provides a timeline of research on form-focused instruction (FFI). Over the past 40 years, research on the role of instruction has undergone many changes. Much of the early research concentrated on determining whether formal instruction makes any difference in the development of learner language. This question was motivated in part by…

  19. Estimating Focus and Radial Distances, and Fault Residuals from CD Player Sensor Signals by use of a Kalman Estimator

    DEFF Research Database (Denmark)

    Odgaard, Peter Fogh; Stoustrup, Jakob; Andersen, Palle

    2003-01-01

    Cross coupling between focus and radial loops in Compact Disc players is a problem both in nominal operations, but also in detection of defects such as scratches and finger prints. Using a Kalman estimator with an internal reference, the actual focus and radial distances are estimated. The sensor...

  20. Research and Its Relationship to Nurse Education: Focus and Capacity.

    Science.gov (United States)

    Newell, Robert

    2002-01-01

    Examination of two British mental health journals and a government document on the future of nursing found a lack of focus on clinical research and little reference to the role of research and development in practice. The increasing importance of evidence-based practice demands a strategy for developing nurses' capacity to understand, undertake,…

  1. The Research Focus of Nations: Economic vs. Altruistic Motivations.

    Science.gov (United States)

    Klavans, Richard; Boyack, Kevin W

    2017-01-01

    What motivates the research strategies of nations and institutions? We suggest that research primarily serves two masters-altruism and economic growth. Some nations focus more research in altruistic (or non-economic) fields while others focus more research in fields associated with economic growth. What causes this difference? Are there characteristics that would suggest why a nation is more aligned with altruism or economic growth? To answer this question, we have identified nine major fields of research by analyzing the publication activity of 4429 institutions using Scopus data. Two fields of research are clearly altruistic (there is relatively little involvement by industry) and two fields are clearly aligned with economic growth. The altruistic vs. economic nature of nations based on their publication profiles across these fields is correlated with national indicators on wealth, education, capitalism, individualism, power, religion, and language. While previous research has suggested that national research strategy is aligned with national wealth, our analysis shows that national wealth is not highly correlated with the tradeoff between altruistic and economic motives. Instead, the tradeoff is largely captured by a culture of individualism. Accordingly, implications for national research strategies are discussed.

  2. Clinical Perspective Qualitative adolescent health researchfocus ...

    African Journals Online (AJOL)

    This paper introduces nine steps that are recommended in conducting focus group discussions in rural communities and gives an example of how they can appropriately and fruitfully be employed in adolescent health behavioural research. The paper also reviewed issues related to methods of data collection, data analysis, ...

  3. Focusing Information Systems Post-Graduate Research Projects

    Directory of Open Access Journals (Sweden)

    Gail Ridley

    1996-11-01

    Full Text Available This paper reports on an investigation of mechanisms that assist Information Systems post-graduate research students to focus their projects. An evaluation is presented of the experiences of Information Systems research students in focussing their research projects based on a survey conducted of students who participated in two of the first three Information Systems doctoral consortia to be held in Australia. The survey sought to determine whether a doctoral consortium or 'systematic expert review' is the most valuable mechanism for focussing a research proposal. Systematic expert review was considered by the students to be more effective than the doctoral consortium process for the purpose of focussing their research project proposals.

  4. Focus Group Interview in Family Practice Research: Implementing a qualitative research method

    OpenAIRE

    Wood, Marjorie L.

    1992-01-01

    Focus group interviews, described as a qualitative research method with good potential in family medicine, are traced from their origins in market research to their growing role in sociology and medicine. Features of this method are described, including design, conduct, and analysis. Both proven and potential areas for primary care research using focus groups are outlined.

  5. The Focus on Youth Prevention and Education Research Programme

    Directory of Open Access Journals (Sweden)

    Lynette Deveaux

    2016-10-01

    Full Text Available Like many developing or transitional countries affected by the HIV epidemic, The Bahamas has been deeply committed to HIV and sexually transmitted infection reduction and continues to make great strides in controlling the epidemic within its boundaries. Encouraged by the impact of the Focus on Youth Caribbean (FOYC, a school-based HIV/AIDS prevention programme and its parenting component on Grade 6 and Grade 10 students and their parents, a team of researchers from The Bahamas and the United States sought to implement a similar programme at a national level, while simultaneously evaluating factors that impact the sustainability of sexual risk-reduction programmes like FOYC. This paper describes five research projects conducted in The Bahamas between 1998 and 2016 and includes a list of over 40 published research articles

  6. Ganando Confianza: Research Focus Groups with Immigrant Mexican Mothers.

    Science.gov (United States)

    Hausmann-Stabile, Carolina; Zayas, Luis H; Runes, Sandra; Abenis-Cintron, Anna; Calzada, Esther

    2011-03-01

    Immigrant families with children with developmental disabilities must be served using culturally sensitive approaches to service and research to maximize treatment benefits. In an effort to better understand cultural issues relevant to the provision of parenting programs for immigrant Mexican mothers of children with developmental disabilities, we conducted sustained focus groups through which we could learn more about our participants and thereby improve services. This paper reports on the challenges and lessons learned from these groups. We characterize the key lessons as (a) recruitment and retention is more than agreement to participate; (b) confidentiality is not just a word but an activity; (c) the complicated nature of language; (d) cultural norms shape the group process; (e) appreciating the value of taking time; and (f) gender issues and group interaction. Service providers and researchers who work with Mexican families may benefit from our experiences as they promote and develop programs and projects in the developmental disabilities field.

  7. Revisiting the use of focus group in social research

    Directory of Open Access Journals (Sweden)

    Betina Freidin

    2016-06-01

    Full Text Available The methodological reflections on focus groups presented in this article draw from a research project on middle-class people living in Metropolitan Buenos Aires. The study addresses health discourses and practices in the contemporary scenario characterized by the diversification of specialists, the growing media coverage of recommendations of healthy living and wellbeing, the implementation of public policies on health promotion, and the expansion of the industry of related products and services.  The objective of the article is to reflect, based on our fieldwork experience, on two aspects that have received special attention in the recent methodological literature: the criteria to compose the groups and their consequences on the conversational dynamic, and the strategies to account for the group interaction in data analysis. Included in the latter, we explore the potential of GF research to observe health identity work. We frame our study and the decisions about design issues into the current debates on the variety of uses of the research group methodology.

  8. Translational toxicology: a developmental focus for integrated research strategies.

    Science.gov (United States)

    Hughes, Claude; Waters, Michael; Allen, David; Obasanjo, Iyabo

    2013-09-30

    Given that toxicology studies the potential adverse effects of environmental exposures on various forms of life and that clinical toxicology typically focuses on human health effects, what can and should the relatively new term of "translational toxicology" be taken to mean? Our assertion is that the core concept of translational toxicology must incorporate existing principles of toxicology and epidemiology, but be driven by the aim of developing safe and effective interventions beyond simple reduction or avoidance of exposure to prevent, mitigate or reverse adverse human health effects of exposures.The field of toxicology has now reached a point where advances in multiple areas of biomedical research and information technologies empower us to make fundamental transitions in directly impacting human health. Translational toxicology must encompass four action elements as follows: 1) Assessing human exposures in critical windows across the lifespan; 2) Defining modes of action and relevance of data from animal models; 3) Use of mathematical models to develop plausible predictions as the basis for: 4) Protective and restorative human health interventions. The discussion focuses on the critical window of in-utero development. Exposure assessment, basic toxicology and development of certain categories of mathematical models are not new areas of research; however overtly integrating these in order to conceive, assess and validate effective interventions to mitigate or reverse adverse effects of environmental exposures is our novel opportunity. This is what we should do in translational toxicology so that we have a portfolio of interventional options to improve human health that include both minimizing exposures and specific preventative/restorative/mitigative therapeutics.

  9. Plutonium Focus Area research and development plan. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    The Department of Energy (DOE) committed to a research and development program to support the technology needs for converting and stabilizing its nuclear materials for safe storage. The R and D Plan addresses five of the six material categories from the 94-1 Implementation Plan: plutonium (Pu) solutions, plutonium metals and oxides, plutonium residues, highly enriched uranium, and special isotopes. R and D efforts related to spent nuclear fuel (SNF) stabilization were specifically excluded from this plan. This updated plan has narrowed the focus to more effectively target specific problem areas by incorporating results form trade studies. Specifically, the trade studies involved salt; ash; sand, slag, and crucible (SS and C); combustibles; and scrub alloy. The plan anticipates possible disposition paths for nuclear materials and identifies resulting research requirements. These requirements may change as disposition paths become more certain. Thus, this plan represents a snapshot of the current progress and will continue to be updated on a regular basis. The paper discusses progress in safeguards and security, plutonium stabilization, special isotopes stabilization, highly-enriched uranium stabilization--MSRE remediation project, storage technologies, engineered systems, core technology, and proposed DOE/Russian technology exchange projects.

  10. Plutonium Focus Area research and development plan. Revision 1

    International Nuclear Information System (INIS)

    1996-11-01

    The Department of Energy (DOE) committed to a research and development program to support the technology needs for converting and stabilizing its nuclear materials for safe storage. The R and D Plan addresses five of the six material categories from the 94-1 Implementation Plan: plutonium (Pu) solutions, plutonium metals and oxides, plutonium residues, highly enriched uranium, and special isotopes. R and D efforts related to spent nuclear fuel (SNF) stabilization were specifically excluded from this plan. This updated plan has narrowed the focus to more effectively target specific problem areas by incorporating results form trade studies. Specifically, the trade studies involved salt; ash; sand, slag, and crucible (SS and C); combustibles; and scrub alloy. The plan anticipates possible disposition paths for nuclear materials and identifies resulting research requirements. These requirements may change as disposition paths become more certain. Thus, this plan represents a snapshot of the current progress and will continue to be updated on a regular basis. The paper discusses progress in safeguards and security, plutonium stabilization, special isotopes stabilization, highly-enriched uranium stabilization--MSRE remediation project, storage technologies, engineered systems, core technology, and proposed DOE/Russian technology exchange projects

  11. Cost Estimation for Research Reactor Decommissioning

    International Nuclear Information System (INIS)

    2013-01-01

    One of the IAEA's statutory objectives is to 'seek to accelerate and enlarge the contribution of atomic energy to peace, health and prosperity throughout the world'. One way this objective is achieved is through the publication of a range of technical series. Two of these are the IAEA Nuclear Energy Series and the IAEA Safety Standards Series. According to Article III.A.6 of the IAEA Statute, the safety standards establish 'standards of safety for protection of health and minimization of danger to life and property.' The safety standards include the Safety Fundamentals, Safety Requirements and Safety Guides. These standards are written primarily in a regulatory style, and are binding on the IAEA for its own programmes. The principal users are the regulatory bodies in Member States and other national authorities. The IAEA Nuclear Energy Series comprises reports designed to encourage and assist R and D on, and application of, nuclear energy for peaceful uses. This includes practical examples to be used by owners and operators of utilities in Member States, implementing organizations, academia, and government officials, among others. This information is presented in guides, reports on technology status and advances, and best practices for peaceful uses of nuclear energy based on inputs from international experts. The IAEA Nuclear Energy Series complements the IAEA Safety Standards Series. The purpose of this publication is to develop a costing methodology and a software tool in order to support cost estimation for research reactor decommissioning. The costing methodology is intended for the preliminary cost estimation stages for research reactor decommissioning with limited inventory data and other input data available. Existing experience in decommissioning costing is considered. As the basis for the cost calculation structure, the costing model uses the International Structure for Decommissioning Costing (ISDC) that is recommended by the IAEA, the Organisation for

  12. Contingency Cost estimation for Research reactor Decommissioning

    International Nuclear Information System (INIS)

    Jin, Hyung Gon; Hong, Yun Jeong

    2016-01-01

    There are many types of cost items in decommissioning cost estimation, however, contingencies are for unforeseen elements of cost within the defined project scope. Regulatory body wants to reasonable quantification for this issue. Many countries have adopted the breakdown of activity dependent and period-dependent costs to structure their estimates. Period-dependent costs could be broken down into defined time frames to reduce overall uncertainties. Several countries apply this notion by having different contingency factors for different phases of the project. This study is a compilation of contingency cost of research reactor and for each country. Simulation techniques using TRIM, MATLAB, and PSpice can be useful tools for designing detector channels. Thus far TRIM, MATLAB and PSpice have been used to calculate the detector current output pulse for SiC semiconductor detectors and to model the pulses that propagate through potential detector channels. This model is useful for optimizing the detector and the resolution for application to neutron monitoring in the Generation IV power reactors

  13. Contingency Cost estimation for Research reactor Decommissioning

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Hyung Gon; Hong, Yun Jeong [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    There are many types of cost items in decommissioning cost estimation, however, contingencies are for unforeseen elements of cost within the defined project scope. Regulatory body wants to reasonable quantification for this issue. Many countries have adopted the breakdown of activity dependent and period-dependent costs to structure their estimates. Period-dependent costs could be broken down into defined time frames to reduce overall uncertainties. Several countries apply this notion by having different contingency factors for different phases of the project. This study is a compilation of contingency cost of research reactor and for each country. Simulation techniques using TRIM, MATLAB, and PSpice can be useful tools for designing detector channels. Thus far TRIM, MATLAB and PSpice have been used to calculate the detector current output pulse for SiC semiconductor detectors and to model the pulses that propagate through potential detector channels. This model is useful for optimizing the detector and the resolution for application to neutron monitoring in the Generation IV power reactors.

  14. LIS Practitioner-focused Research Trends Toward Open Access Journals, Academic-focused Research Toward Traditional Journals

    Directory of Open Access Journals (Sweden)

    Richard Hayman

    2018-03-01

    with academic-student collaborations (21.5%, practitioner librarian collaborations (15.5%, and librarian-academic collaborations (13.2%. Conclusion – LIS practitioner-focused research tends to appear more often in open access journals, while academic-focused researcher tends to appear more often in non-OA journals. These trends also appear in research collaborations, with co-authored works involving librarians appearing more often in OA journals, and collaborations that include academics more likely to appear in non-OA journals.

  15. A review of the effects on IRT item parameter estimates with a focus on misbehaving common items in test equating

    Directory of Open Access Journals (Sweden)

    Michalis P Michaelides

    2010-10-01

    Full Text Available Many studies have investigated the topic of change or drift in item parameter estimates in the context of Item Response Theory. Content effects, such as instructional variation and curricular emphasis, as well as context effects, such as the wording, position, or exposure of an item have been found to impact item parameter estimates. The issue becomes more critical when items with estimates exhibiting differential behavior across test administrations are used as common for deriving equating transformations. This paper reviews the types of effects on IRT item parameter estimates and focuses on the impact of misbehaving or aberrant common items on equating transformations. Implications relating to test validity and the judgmental nature of the decision to keep or discard aberrant common items are discussed, with recommendations for future research into more informed and formal ways of dealing with misbehaving common items.

  16. A Review of the Effects on IRT Item Parameter Estimates with a Focus on Misbehaving Common Items in Test Equating.

    Science.gov (United States)

    Michaelides, Michalis P

    2010-01-01

    Many studies have investigated the topic of change or drift in item parameter estimates in the context of item response theory (IRT). Content effects, such as instructional variation and curricular emphasis, as well as context effects, such as the wording, position, or exposure of an item have been found to impact item parameter estimates. The issue becomes more critical when items with estimates exhibiting differential behavior across test administrations are used as common for deriving equating transformations. This paper reviews the types of effects on IRT item parameter estimates and focuses on the impact of misbehaving or aberrant common items on equating transformations. Implications relating to test validity and the judgmental nature of the decision to keep or discard aberrant common items are discussed, with recommendations for future research into more informed and formal ways of dealing with misbehaving common items.

  17. Evidence-based research: understanding the best estimate

    Directory of Open Access Journals (Sweden)

    Bauer JG

    2016-09-01

    Full Text Available Janet G Bauer,1 Sue S Spackman,2 Robert Fritz,2 Amanjyot K Bains,3 Jeanette Jetton-Rangel3 1Advanced Education Services, 2Division of General Dentistry, 3Center of Dental Research, Loma Linda University School of Dentistry, Loma Linda, CA, USA Introduction: Best estimates of intervention outcomes are used when uncertainties in decision making are evidenced. Best estimates are often, out of necessity, from a context of less than quality evidence or needing more evidence to provide accuracy. Purpose: The purpose of this article is to understand the best estimate behavior, so that clinicians and patients may have confidence in its quantification and validation. Methods: To discover best estimates and quantify uncertainty, critical appraisals of the literature, gray literature and its resources, or both are accomplished. Best estimates of pairwise comparisons are calculated using meta-analytic methods; multiple comparisons use network meta-analysis. Manufacturers provide margins of performance of proprietary material(s. Lower margin performance thresholds or requirements (functional failure of materials are determined by a distribution of tests to quantify performance or clinical competency. The same is done for the high margin performance thresholds (estimated true value of success and clinician-derived critical values (material failure to function clinically. This quantification of margins and uncertainties assists clinicians in determining if reported best estimates are progressing toward true value as new knowledge is reported. Analysis: The best estimate of outcomes focuses on evidence-centered care. In stochastic environments, we are not able to observe all events in all situations to know without uncertainty the best estimates of predictable outcomes. Point-in-time analyses of best estimates using quantification of margins and uncertainties do this. Conclusion: While study design and methodology are variables known to validate the quality of

  18. How to conduct focus groups: researching group priorities through discussion.

    Science.gov (United States)

    1992-01-01

    Focus groups serve to uncover priorities and beliefs of a target group, but health project designers do not always take the time to seek this information beforehand. Focus groups also allow various local subgroups to communicate their concerns before the project starts. Focus groups can also breed ideas and dialogue that individual interviews cannot and they provide baseline information so managers can determine if attitudes or priorities have resulted from the project. Diverse people have different beliefs, e.g., women who have young children view oral rehydration therapy differently from women with no children. Project designers can use these basic differences to arrive at some conclusions about general attitudes. Focus group facilitators should have a discussion outline to help keep the group on the topic of concern. They should limit sessions to 60-90 minutes. Each focus groups should include 8-10 people. It is important to have members of various community subgroups in each group. Yet group designers should be careful not to include within the same group, those who may intimidate other people in the group, e.g., in situations where farmers depend on middlemen, farmers may not be open if middlemen are also in the focus group. Facilitators should launch each session with an attempt to encourage the members to be open and to feel comfortable. For example, in Malawi, a facilitator leads her focus group discussions with songs. Stories are another icebreaker. It is important that all focus groups centering around a certain project discuss the same topics. Facilitators need to stress to the group that all discussions are to be kept confidential. The designers should also carefully word the questions so that facilitators will not impart their bias. Facilitators should not direct the group to certain conclusions, but instead keep the discussions focused.

  19. EPA Toxicologists Focus Innovative Research on PFAS Compounds

    Science.gov (United States)

    EPA researchers have partnered with researchers at the National Toxicology Program to develop a tiered testing approach to quickly generate toxicity and kinetic information for approximately 75 PFAS compounds.

  20. Focused ultrasound transducer spatial peak intensity estimation: a comparison of methods

    Science.gov (United States)

    Civale, John; Rivens, Ian; Shaw, Adam; ter Haar, Gail

    2018-03-01

    Characterisation of the spatial peak intensity at the focus of high intensity focused ultrasound transducers is difficult because of the risk of damage to hydrophone sensors at the high focal pressures generated. Hill et al (1994 Ultrasound Med. Biol. 20 259-69) provided a simple equation for estimating spatial-peak intensity for solid spherical bowl transducers using measured acoustic power and focal beamwidth. This paper demonstrates theoretically and experimentally that this expression is only strictly valid for spherical bowl transducers without a central (imaging) aperture. A hole in the centre of the transducer results in over-estimation of the peak intensity. Improved strategies for determining focal peak intensity from a measurement of total acoustic power are proposed. Four methods are compared: (i) a solid spherical bowl approximation (after Hill et al 1994 Ultrasound Med. Biol. 20 259-69), (ii) a numerical method derived from theory, (iii) a method using measured sidelobe to focal peak pressure ratio, and (iv) a method for measuring the focal power fraction (FPF) experimentally. Spatial-peak intensities were estimated for 8 transducers at three drive powers levels: low (approximately 1 W), moderate (~10 W) and high (20-70 W). The calculated intensities were compared with those derived from focal peak pressure measurements made using a calibrated hydrophone. The FPF measurement method was found to provide focal peak intensity estimates that agreed most closely (within 15%) with the hydrophone measurements, followed by the pressure ratio method (within 20%). The numerical method was found to consistently over-estimate focal peak intensity (+40% on average), however, for transducers with a central hole it was more accurate than using the solid bowl assumption (+70% over-estimation). In conclusion, the ability to make use of an automated beam plotting system, and a hydrophone with good spatial resolution, greatly facilitates characterisation of the FPF, and

  1. Canada's International Education Strategy: Focus on Scholarships. CBIE Research

    Science.gov (United States)

    Embleton, Sheila

    2011-01-01

    Based on a survey of approximately 40 professionals involved in various disciplines associated with international education across Canada, this study examines Canada's (federal, provincial, and territorial government) offering of scholarships to international students. Focused at the university level, the study elaborates on relevant international…

  2. Report Focuses on Integrity and Accessibility of Research Data

    Science.gov (United States)

    Showstack, Randy

    2009-08-01

    Rapid advances in digital technologies and enormous increases in the amount of data generated by research projects and a variety of instruments and sensors are providing new research opportunities. These advances, however, also can present challenges for ensuring that digital technologies are not used inappropriately and for managing an increasing amount of data, according to a new report issued by the U.S. National Academy of Sciences, National Academy of Engineering, and Institute of Medicine on 22 July. The new report, entitled “Ensuring the integrity, accessibility, and stewardship of research data in the digital age,” provides general principles and recommendations about the handling of research data. The report notes that the development of policies, standards, and infrastructure “is a critically important task” that will require a sustained effort from stakeholders including researchers, research institutions and sponsors, and professional societies and journals.

  3. Advances in research methods for information systems research data mining, data envelopment analysis, value focused thinking

    CERN Document Server

    Osei-Bryson, Kweku-Muata

    2013-01-01

    Advances in social science research methodologies and data analytic methods are changing the way research in information systems is conducted. New developments in statistical software technologies for data mining (DM) such as regression splines or decision tree induction can be used to assist researchers in systematic post-positivist theory testing and development. Established management science techniques like data envelopment analysis (DEA), and value focused thinking (VFT) can be used in combination with traditional statistical analysis and data mining techniques to more effectively explore

  4. Airbreathing Hypersonic Systems Focus at NASA Langley Research Center

    Science.gov (United States)

    Hunt, James L.; Rausch, Vincent L.

    1998-01-01

    This paper presents the status of the airbreathing hypersonic airplane and space-access vehicle design matrix, reflects on the synergies and issues, and indicates the thrust of the effort to resolve the design matrix and to focus/advance systems technology maturation. Priority is given to the design of the vision operational vehicles followed by flow-down requirements to flight demonstrator vehicles and their design for eventual consideration in the Future-X Program.

  5. Interview series focuses on IDRC-funded research on climate ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    In Conversation is a series of interviews and videos of research partners working on climate change adaptation projects in Africa, Asia, and Latin America and the Caribbean, funded through IDRC's Climate Change and Water program.

  6. Focus on CSIR research in pollution and waste: environmental health

    CSIR Research Space (South Africa)

    Godfrey, Linda K

    2007-08-01

    Full Text Available A healthy population is seen as an important precondition for economic growth and competitiveness. Research into environmental health is therefore concerned with understanding the exposure and magnitude of impact on humans from environmental hazards...

  7. "Ganando Confianza": Research Focus Groups with Immigrant Mexican Mothers

    Science.gov (United States)

    Hausmann-Stabile, Carolina; Zayas, Luis H.; Runes, Sandra; Abenis-Cintron, Anna; Calzada, Esther

    2011-01-01

    Immigrant families with children with developmental disabilities must be served using culturally sensitive approaches to service and research to maximize treatment benefits. In an effort to better understand cultural issues relevant to the provision of parenting programs for immigrant Mexican mothers of children with developmental disabilities, we…

  8. A Research Focused on Improving Vocalisation Level on Violin Education

    Science.gov (United States)

    Parasiz, Gökalp

    2018-01-01

    The research aimed to improve vocalisation levels of music teacher's candidates on performance works for violin education moving from difficulties faced by prospective teachers. At the same time, it was aimed to provide new perspectives to violin educators. Study group was composed of six 3rd grade students studying violin education in a State…

  9. Focus Article: Replication in Second Language Writing Research

    Science.gov (United States)

    Porte, Graeme; Richards, Keith

    2012-01-01

    This paper discusses the meaning and range of replication in L2 research from both quantitative and qualitative perspectives. In the first half of the paper, it will be argued that key quantitative studies need to be replicated to have their robustness and generalizability tested and that this is a requirement of scientific inquiry. Such research…

  10. Faculty at Work: Focus on Research, Scholarship, and Service.

    Science.gov (United States)

    Blackburn, Robert T.; And Others

    1991-01-01

    A study compared selected personal and environmental motivational variables in college faculty with allocation of work effort to research, scholarship, and service. Faculty were from eight liberal arts and sciences departments in a range of institution types. For all institutional types, self-valuation motivators significantly accounted for the…

  11. Refocusing International Astronomy Education Research Using a Cognitive Focus

    Science.gov (United States)

    Slater, Timothy F.; Slater, Stephanie J.

    2015-08-01

    For over 40 years, the international astronomy education community has given its attention to cataloging the substantial body of "misconceptions" in individual's thinking about astronomy, and to addressing the consequences of those misconceptions in the science classroom. Despite the tremendous amount of effort given to researching and disseminating information related to misconceptions, and the development of a theory of conceptual change to mitigate misconceptions, progress continues to be less than satisfying. An analysis of the literature and our own research has motivated the CAPER Center for Astronomy & Physics Education Research to advance a new model that allowing us to operate on students' astronomical learning difficulties in a more fruitful manner. Previously, much of the field's work binned erroneous student thinking into a single construct, and from that basis, curriculum developers and instructors addressed student misconceptions with a single instructional strategy. In contrast this model suggests that "misconceptions" are a mixture of at least four learning barriers: incorrect factual information, inappropriately applied mental algorithms (e.g., phenomenological primitives), insufficient cognitive structures (e.g., spatial reasoning), and affective/emotional difficulties. Each of these types of barriers should be addressed with an appropriately designed instructional strategy. Initial applications of this model to learning problems in astronomy and the space sciences have been fruitful, suggesting that an effort towards categorizing persistent learning difficulties in astronomy beyond the level of "misconceptions" may allow our community to craft tailored and more effective learning experiences for our students and the general public.

  12. Knowledge Exchange: selecting research opportunities through estimation.

    Science.gov (United States)

    Cudd, Peter; Fowler-Davis, Sally; Evans, Laura; Mawson, Sue

    2015-01-01

    A systematic way to select new ideas for research and development between two organisations is reported. It was applied to ideas that were generated from acute clinical settings by Occupational Therapists with a view to collaborate with nearby university academics from many disciplines. The process, assessment factors, use of ordinal scales with thresholding and an arbitrary formula are described. Challenges in the approach are discussed. Suitability for use by others in the AT field, other care related or even very different contexts is noted with some adaption and caveats.

  13. Family-Focused Autism Spectrum Disorder Research: A Review of the Utility of Family Systems Approaches

    Science.gov (United States)

    Cridland, Elizabeth K.; Jones, Sandra C.; Magee, Christopher A.; Caputi, Peter

    2014-01-01

    A family member with an autism spectrum disorder presents pervasive and bidirectional influences on the entire family system, suggesting a need for family-focused autism spectrum disorder research. While there has been increasing interest in this research area, family-focused autism spectrum disorder research can still be considered relatively…

  14. Health Services Research and Health Economy - Quality Care Training in Gynaecology, with Focus On Gynaecological Oncology.

    Science.gov (United States)

    Lux, M P; Fasching, P A; Loehberg, C R; Jud, S M; Schrauder, M G; Bani, M R; Thiel, F C; Hack, C C; Hildebrandt, T; Beckmann, M W

    2011-12-01

    In the era of cost increases and reduced resources in the German healthcare system, the value of health services research and health economics is increasing more and more. Health services research attempts to develop concepts for the most effective ways to organise, manage, finance and deliver high-quality care and evaluates the implementation of these concepts with regard to daily routine conditions. Goals are the assessment of benefits and the economic advantages and disadvantages of new and established diagnostic methods, drugs and vaccines. Regarding these goals, it is clear that health services research goes hand in hand with health economics, which evaluates the benefits of diagnostic and therapeutic procedures in relation to the costs. Both scientific fields have focus principally on gynaecology and particularly on gynaecological oncology in Germany, as can be seen by numerous publications. These present several advantages compared with clinical trials - they uncover gaps in health care, question the material, staffing and consequently the financial resources required and they allow the estimation of value and the comparison of different innovations to identify the best options for our patients.

  15. Precincts and Prospects in the Use of Focus Groups in Social and Behavioral Science Research

    Science.gov (United States)

    Sagoe, Dominic

    2012-01-01

    Over the past few years, the focus group method has assumed a very important role as a method for collecting qualitative data in social and behavioural science research. This article elucidates theoretical and practical problems and prospects associated with the use of focus groups as a qualitative research method in social and behavioural science…

  16. The small-animal radiation research platform (SARRP): dosimetry of a focused lens system

    Energy Technology Data Exchange (ETDEWEB)

    Deng Hua [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Kennedy, Christopher W [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Armour, Elwood [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Tryggestad, Erik [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Ford, Eric [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); McNutt, Todd [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Jiang Licai [OSMIC Inc., 1900 Taylor Rd., Auburn Hills, MI (United States); Wong, John [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States)

    2007-05-21

    A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min{sup -1} at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of {+-}5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD.

  17. The small-animal radiation research platform (SARRP): dosimetry of a focused lens system.

    Science.gov (United States)

    Deng, Hua; Kennedy, Christopher W; Armour, Elwood; Tryggestad, Erik; Ford, Eric; McNutt, Todd; Jiang, Licai; Wong, John

    2007-05-21

    A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min(-1) at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of +/-5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD.

  18. The small-animal radiation research platform (SARRP): dosimetry of a focused lens system

    International Nuclear Information System (INIS)

    Deng Hua; Kennedy, Christopher W; Armour, Elwood; Tryggestad, Erik; Ford, Eric; McNutt, Todd; Jiang Licai; Wong, John

    2007-01-01

    A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min -1 at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of ±5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD

  19. Focus group interview: an underutilized research technique for improving theory and practice in health education.

    Science.gov (United States)

    Basch, C E

    1987-01-01

    The purpose of this article is to increase awareness about and stimulate interest in using focus group interviews, a qualitative research technique, to advance the state-of-the-art of education and learning about health. After a brief discussion of small group process in health education, features of focus group interviews are presented, and a theoretical framework for planning a focus group study is summarized. Then, literature describing traditional and health-related applications of focus group interviews is reviewed and a synthesis of methodological limitations and advantages of this technique is presented. Implications are discussed regarding: need for more inductive qualitative research in health education; utility of focus group interviews for research and for formative and summative evaluation of health education programs; applicability of marketing research to understanding and influencing consumer behavior, despite notable distinctions between educational initiatives and marketing; and need for professional preparation faculty to consider increasing emphasis on qualitative research methods.

  20. Estimation of Oil Production Rates in Reservoirs Exposed to Focused Vibrational Energy

    KAUST Repository

    Jeong, Chanseok

    2014-01-01

    Elastic wave-based enhanced oil recovery (EOR) is being investigated as a possible EOR method, since strong wave motions within an oil reservoir - induced by earthquakes or artificially generated vibrations - have been reported to improve the production rate of remaining oil from existing oil fields. To date, there are few theoretical studies on estimating how much bypassed oil within an oil reservoir could be mobilized by such vibrational stimulation. To fill this gap, this paper presents a numerical method to estimate the extent to which the bypassed oil is mobilized from low to high permeability reservoir areas, within a heterogeneous reservoir, via wave-induced cross-flow oscillation at the interface between the two reservoir permeability areas. This work uses the finite element method to numerically obtain the pore fluid wave motion within a one-dimensional fluid-saturated porous permeable elastic solid medium embedded in a non-permeable elastic semi-infinite solid. To estimate the net volume of mobilized oil from the low to the high permeability area, a fluid flow hysteresis hypothesis is adopted to describe the behavior at the interface between the two areas. Accordingly, the fluid that is moving from the low to the high permeability areas is assumed to transport a larger volume of oil than the fluid moving in the opposite direction. The numerical experiments were conducted by using a prototype heterogeneous oil reservoir model, subjected to ground surface dynamic loading operating at low frequencies (1 to 50 Hz). The numerical results show that a sizeable amount of oil could be mobilized via the elastic wave stimulation. It is observed that certain wave frequencies are more effective than others in mobilizing the remaining oil. We remark that these amplification frequencies depend on the formation’s elastic properties. This numerical work shows that the wave-based mobilization of the bypassed oil in a heterogeneous oil reservoir is feasible, especially

  1. Focusing the HIV response through estimating the major modes of HIV transmission: a multi-country analysis

    Science.gov (United States)

    Gouws, Eleanor; Cuchi, Paloma

    2012-01-01

    Objective An increasing number of countries have been estimating the distribution of new adult HIV infections by modes of transmission (MOT) to help prioritise prevention efforts. We compare results from studies conducted between 2008 and 2012 and discuss their use for planning and responding to the HIV epidemic. Methods The UNAIDS recommended MOT model helps countries to estimate the proportion of new HIV infections that occur through key transmission modes including sex work, injecting drug use (IDU), men having sex with men (MSM), multiple sexual partnerships, stable relationships and medical interventions. The model typically forms part of a country-led process that includes a comprehensive review of epidemiological data. Recent revisions to the model are described. Results Modelling results from 25 countries show large variation between and within regions. In sub-Saharan Africa, new infections occur largely in the general heterosexual population because of multiple partnerships or in stable discordant relationships, while sex work contributes significantly to new infections in West Africa. IDU and sex work are the main contributors to new infections in the Middle East and North Africa, with MSM the main contributor in Latin America. Patterns vary substantially between countries in Eastern Europe and Asia in terms of the relative contribution of sex work, MSM, IDU and spousal transmission. Conclusions The MOT modelling results, comprehensive review and critical assessment of data in a country can contribute to a more strategically focused HIV response. To strengthen this type of research, improved epidemiological and behavioural data by risk population are needed. PMID:23172348

  2. Design Research with a Focus on Learning Processes: An Overview on Achievements and Challenges

    Science.gov (United States)

    Prediger, Susanne; Gravemeijer, Koeno; Confrey, Jere

    2015-01-01

    Design research continues to gain prominence as a significant methodology in the mathematics education research community. This overview summarizes the origins and the current state of design research practices focusing on methodological requirements and processes of theorizing. While recognizing the rich variations in the foci and scale of design…

  3. Evaluating direct medical expenditures estimation methods of adults using the medical expenditure panel survey: an example focusing on head and neck cancer.

    Science.gov (United States)

    Coughlan, Diarmuid; Yeh, Susan T; O'Neill, Ciaran; Frick, Kevin D

    2014-01-01

    To inform policymakers of the importance of evaluating various methods for estimating the direct medical expenditures for a low-incidence condition, head and neck cancer (HNC). Four methods of estimation have been identified: 1) summing all health care expenditures, 2) estimating disease-specific expenditures consistent with an attribution approach, 3) estimating disease-specific expenditures by matching, and 4) estimating disease-specific expenditures by using a regression-based approach. A literature review of studies (2005-2012) that used the Medical Expenditure Panel Survey (MEPS) was undertaken to establish the most popular expenditure estimation methods. These methods were then applied to a sample of 120 respondents with HNC, derived from pooled data (2003-2008). The literature review shows that varying expenditure estimation methods have been used with MEPS but no study compared and contrasted all four methods. Our estimates are reflective of the national treated prevalence of HNC. The upper-bound estimate of annual direct medical expenditures of adult respondents with HNC between 2003 and 2008 was $3.18 billion (in 2008 dollars). Comparable estimates arising from methods focusing on disease-specific and incremental expenditures were all lower in magnitude. Attribution yielded annual expenditures of $1.41 billion, matching method of $1.56 billion, and regression method of $1.09 billion. This research demonstrates that variation exists across and within expenditure estimation methods applied to MEPS data. Despite concerns regarding aspects of reliability and consistency, reporting a combination of the four methods offers a degree of transparency and validity to estimating the likely range of annual direct medical expenditures of a condition. © 2013 International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Published by International Society for Pharmacoeconomics and Outcomes Research (ISPOR) All rights reserved.

  4. Directional velocity estimation using focusing along the flow direction - I: Theory and simulation

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt

    2003-01-01

    A new method for directional velocity estimation is presented. The method uses beamformation along the flow direction to generate data in which the correct velocity magnitude can be directly estimated from the shift in position of the received consecutive signals. The shift is found by cross-corr...

  5. State Estimation in Fermentation of Lignocellulosic Ethanol. Focus on the Use of pH Measurements

    DEFF Research Database (Denmark)

    Mauricio Iglesias, Miguel; Gernaey, Krist; Huusom, Jakob Kjøbsted

    2015-01-01

    The application of the continuous-discrete extended Kalman filter (CD-EKF) as a powerful tool for state estimation in biochemical systems is assessed here. Using a fermentation process for ethanol production as a case study, the CD-EKF can effectively estimate the model states even when highly non...

  6. Puzzle-solving in psychology : The neo-Galtonian vs. nomothetic research focuses

    NARCIS (Netherlands)

    Vautier, Stephane; Lacot, Emilie; Veldhuis, Michiel

    We compare the neo-Galtonian and nomothetic approaches of psychological research. While the former focuses on summarized statistics that depict average subjects, the latter focuses on general facts of form 'if conditions then restricted outcomes'. The nomothetic approach does not require

  7. Establishing a research agenda for scientific and technical information (STI) - Focus on the user

    Science.gov (United States)

    Pinelli, Thomas E.

    1992-01-01

    This report addresses the relationship between library science and information science theory and practice, between the development of conceptual understanding, and the practical competence of information professionals. Consideration is given to the concept of research, linking theory with practice, and the reality of theory based practice. Attention is given to the need for research and research priorities, focus on the user and information-seeking behavior, and a user-oriented research agenda for STI.

  8. Establishing a research agenda for Scientific and Technical Information (STI): Focus on the user

    Science.gov (United States)

    Pinelli, Thomas E.

    1992-01-01

    This report addresses the relationship between library science and information science theory and practice, between the development of conceptual understanding, and the practical competence of information professionals. Consideration is given to the concept of research, linking theory with practice, and the reality of theory based practice. Attention is given to the need for research and research priorities, focus on the user and information-seeking behavior, and a user-oriented research agenda for STI.

  9. Planning focus group interviews with asylum seekers: Factors related to the researcher, interpreter and asylum seekers.

    Science.gov (United States)

    Eklöf, Niina; Hupli, Maija; Leino-Kilpi, Helena

    2017-10-01

    The aim of this article was to discuss factors related to the researcher, interpreter and asylum seekers when planning focus group interviews with asylum seekers. Focus group interview is one of the basic data collection methods in descriptive nursing and health research. It has been used in multicultural research, allowing an opportunity to participate without literacy and to have linguistic and cultural support from other participants. Asylum seekers form a specific, vulnerable group, and the growing number of asylum seekers increases the need for research related to them. A culturally, methodologically and ethically high-quality focus group interview is based on the researcher's special knowledge and skills, acknowledgement of asylum seekers as both individuals and part of cultural and communal groups, and careful planning of the interpreter's role during the interviews. © 2017 John Wiley & Sons Ltd.

  10. Focus on CSIR research in water resources: water and human health research in CSIR

    CSIR Research Space (South Africa)

    Genthe, Bettina

    2007-08-01

    Full Text Available The Water and Human Health team researches water related science to address the CSIR’s mandate, national priorities and to improve quality of life for all. The overall aim of the research is to achieve a sustainable balance between the use of water...

  11. [Bioethical Approach for Nursing Research -Focused on the Use of Research Ethics Committees].

    Science.gov (United States)

    Jeong, Ihn Sook

    2015-06-01

    This paper was written to introduce methods of using the research ethics committee (RES) from requesting the initial review to reporting the close-out for nursing researchers. General ethical principles were described by reviewing the 'Bioethics and Safety Act' and other related guidelines, and constructing some questions and answers. The results were composed of three parts; definition of RES, steps in using RES, and archiving. The 7 steps for using RES were; identifying whether the study needed to be reviewed, by the RES identifying whether the study could be exempted, requesting the initial review after preparing documents, requesting the re-review, requesting an amendment review, requesting a continuing review and reporting the close-out. Nursing researchers need to receive RES approval before starting nursing research involving human subjects. Nursing researchers are urged to use the steps reported in this paper to receive RES approval easily and quickly.

  12. Symbolic Interaction and Applied Social Research: A FOCUS ON TRANSLATIONAL SCIENCE RESEARCH1.

    Science.gov (United States)

    Kotarba, Joseph A

    2014-08-01

    In symbolic interaction, a traditional yet unfortunate and unnecessary distinction has been made between basic and applied research. The argument has been made that basic research is intended to generate new knowledge, whereas applied research is intended to apply knowledge to the solution of practical (social and organizational) problems. I will argue that the distinction between basic and applied research in symbolic interaction is outdated and dysfunctional. The masters of symbolic interactionist thought have left us a proud legacy of shaping their scholarly thinking and inquiry in response to and in light of practical issues of the day (e.g., Znaniecki, and Blumer). Current interactionist work continues this tradition in topical areas such as social justice studies. Applied research, especially in term of evaluation and needs assessment studies, can be designed to serve both basic and applied goals. Symbolic interaction provides three great resources to do this. The first is its orientation to dynamic sensitizing concepts that direct research and ask questions instead of supplying a priori and often impractical answers. The second is its orientation to qualitative methods, and appreciation for the logic of grounded theory. The third is interactionism's overall holistic approach to interfacing with the everyday life world. The primary illustrative case here is the qualitative component of the evaluation of an NIH-funded, translational medical research program. The qualitative component has provided interactionist-inspired insights into translational research, such as examining cultural change in medical research in terms of changes in the form and content of formal and informal discourse among scientists; delineating the impact of significant symbols such as "my lab" on the social organization of science; and appreciating the essence of the self-concept "scientist" on the increasingly bureaucratic and administrative identities of medical researchers. This

  13. Implications for Focusing Research in Career and Technical Education and Workforce Development

    Science.gov (United States)

    Lambeth, Jeanea M.; Joerger, Richard M.; Elliot, Jack

    2009-01-01

    Education and educational research is shaped by philosophy, psychology, practice, and ever changing educational policies. Previous studies have expressed a need for a relevant and focused research agenda for career and technical education (CTE), workforce development education and career and technical education. A need for a relevant and timely…

  14. Linking Teacher Evaluation to Professional Development: Focusing on Improving Teaching and Learning. Research & Policy Brief

    Science.gov (United States)

    Goe, Laura; Biggers, Kietha; Croft, Andrew

    2012-01-01

    Recently, teacher evaluation has become a major focus in educational policy debates and research efforts. This increased attention to teacher evaluation has raised questions about the relationship between evaluation and student outcomes. Rivkin, Hanushek, and Kain (2005) and others have demonstrated with value-added research that there are…

  15. Process research on Emotionally Focused Therapy (EFT) for couples: linking theory to practice.

    Science.gov (United States)

    Greenman, Paul S; Johnson, Susan M

    2013-03-01

    The focus of this article is on the link among theory, process, and outcome in the practice of Emotionally Focused Therapy (EFT) for couples. We describe the EFT model of change and the EFT perspective on adult love as the reflection of underlying attachment processes. We outline the manner in which theory and research inform EFT interventions. This leads into a detailed review of the literature on the processes of change in EFT. We highlight the client responses and therapist operations that have emerged from process research and their relation to treatment outcomes. We discuss the implications of this body of research for clinical practice and training. © FPI, Inc.

  16. Estimation of Oil Production Rates in Reservoirs Exposed to Focused Vibrational Energy

    KAUST Repository

    Jeong, Chanseok; Kallivokas, Loukas F.; Huh, Chun; Lake, Larry W.

    2014-01-01

    the production rate of remaining oil from existing oil fields. To date, there are few theoretical studies on estimating how much bypassed oil within an oil reservoir could be mobilized by such vibrational stimulation. To fill this gap, this paper presents a

  17. Effects of Focus of Accounting Research on the Quality of Accounting Education in Malaysian Universities

    OpenAIRE

    Kabiru Isa Dandago; Nor Azlina Binti Shaari

    2013-01-01

    This paper reviews the impact of focus of research in accounting on the quality of accounting education in Malaysian Universities. Research in accounting is very important in Malaysian Universities, in particular, and the Malaysian tertiary educational institutions, in general, and it is expected that academic research in accounting would improve the quality of accounting education in the country. The study is mainly a literature review type, with some informal interviews conducted for confir...

  18. Estimating Return on Investment in Translational Research: Methods and Protocols

    Science.gov (United States)

    Trochim, William; Dilts, David M.; Kirk, Rosalind

    2014-01-01

    Assessing the value of clinical and translational research funding on accelerating the translation of scientific knowledge is a fundamental issue faced by the National Institutes of Health and its Clinical and Translational Awards (CTSA). To address this issue, the authors propose a model for measuring the return on investment (ROI) of one key CTSA program, the clinical research unit (CRU). By estimating the economic and social inputs and outputs of this program, this model produces multiple levels of ROI: investigator, program and institutional estimates. A methodology, or evaluation protocol, is proposed to assess the value of this CTSA function, with specific objectives, methods, descriptions of the data to be collected, and how data are to be filtered, analyzed, and evaluated. This paper provides an approach CTSAs could use to assess the economic and social returns on NIH and institutional investments in these critical activities. PMID:23925706

  19. Estimating return on investment in translational research: methods and protocols.

    Science.gov (United States)

    Grazier, Kyle L; Trochim, William M; Dilts, David M; Kirk, Rosalind

    2013-12-01

    Assessing the value of clinical and translational research funding on accelerating the translation of scientific knowledge is a fundamental issue faced by the National Institutes of Health (NIH) and its Clinical and Translational Awards (CTSAs). To address this issue, the authors propose a model for measuring the return on investment (ROI) of one key CTSA program, the clinical research unit (CRU). By estimating the economic and social inputs and outputs of this program, this model produces multiple levels of ROI: investigator, program, and institutional estimates. A methodology, or evaluation protocol, is proposed to assess the value of this CTSA function, with specific objectives, methods, descriptions of the data to be collected, and how data are to be filtered, analyzed, and evaluated. This article provides an approach CTSAs could use to assess the economic and social returns on NIH and institutional investments in these critical activities.

  20. Lin Receives 2010 Natural Hazards Focus Group Award for Graduate Research

    Science.gov (United States)

    2010-11-01

    Ning Lin has been awarded the Natural Hazards Focus Group Award for Graduate Research, given annually to a recent Ph.D. recipient for outstanding contributions to natural hazards research. Lin's thesis is entitled “Multi-hazard risk analysis related to hurricanes.” She is scheduled to present an invited talk in the Extreme Natural Events: Modeling, Prediction, and Mitigation session (NH20) during the 2010 AGU Fall Meeting, held 13-17 December in San Francisco, Calif. Lin will be formally presented with the award at the Natural Hazards focus group reception on 14 December 2010.

  1. Focusing on Cause or Cure?: Priorities and Stakeholder Presence in Childhood Psychiatry Research.

    Science.gov (United States)

    Milner, Lauren C; Cho, Mildred K

    2014-01-01

    Biomedical research is influenced by many factors, including the involvement of stakeholder groups invested in research outcomes. Stakeholder involvement in research efforts raise questions of justice as their specific interests and motivations play a role in directing research resources that ultimately produce knowledge shaping how different conditions (and affected individuals) are understood and treated by society. This issue is highly relevant to child psychiatry research where diagnostic criteria and treatment strategies are often controversial. Biological similarities and stakeholder differences between attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) provide an opportunity to explore this issue by comparing research foci and stakeholder involvement in these conditions. A subset of ADHD and ASD research articles published between 1970-2010 were randomly selected from the PubMed database and coded for research focus, funding source(s), and author-reported conflicts of interest (COIs). Chi-square analyses were performed to identify differences between and within ADHD and ASD research across time. The proportion of ADHD research dedicated to basic, description, and treatment research was roughly similar and remained stable over time, while ASD research showed a significant increase in basic research over the past decade. Government was the primary research funder for both conditions, but for-profit funders were a notable presence in ADHD research, while joint-funding efforts between non-profit and government funders were a notable presence in ASD research. Lastly, COIs were noted more frequently in ADHD than in ASD research. Our study shows significant differences in research foci and funding sources between the conditions, and identifies the specific involvement of for-profit and non-profit groups in ADHD and ASD, respectively. Our findings highlight the relationship between stakeholders outside the research community and

  2. A Review of the Research in Emotionally Focused Therapy for Couples.

    Science.gov (United States)

    Wiebe, Stephanie A; Johnson, Susan M

    2016-09-01

    Emotionally Focused Therapy for Couples (EFT) is a brief evidence-based couple therapy based in attachment theory. Since the development of EFT, efficacy and effectiveness research has accumulated to address a range of couple concerns. EFT meets or exceeds the guidelines for classification as an evidence-based couple therapy outlined for couple and family research. Furthermore, EFT researchers have examined the process of change and predictors of outcome in EFT. Future research in EFT will continue to examine the process of change in EFT and test the efficacy and effectiveness of EFT in new applications and for couples of diverse backgrounds and concerns. © 2016 Family Process Institute.

  3. Estimating Exchange Rate Exposure over Various Return Horizons: Focusing on Major Countries in East Asia

    Directory of Open Access Journals (Sweden)

    Jeong Wook Lee

    2016-12-01

    Full Text Available In this paper, we estimate the exchange rate exposure, indicating the effect of exchange rate movements on firm values, for a sample of 1,400 firms in seven East Asian countries. The exposure estimates based on various exchange rate variables, return horizons and a control variable are compared. A key result from our analysis is that the long term effect of exchange rate movements on firm values is greater than the short term effect. And we find very similar results from using other exchange rate variables such as the U.S. dollar exchange rate, etc. Second, we add exchange rate volatility as a control variable and find that the extent of exposure is not much changed. Third, we examine the changes in exposure to exchange rate volatility with an increase in return horizon. Consequently the ratio of firms with significant exposures increases with the return horizons. Interestingly, the increase of exposure with the return horizons is faster for exposure to volatility than for exposure to exchange rate itself. Taken as a whole, our findings suggest that the so-called "exposure puzzle" may be a matter of the methodology used to measure exposure.

  4. Methodological Reflections on the Use of Asynchronous Online Focus Groups in Health Research

    Directory of Open Access Journals (Sweden)

    Sarah Williams PhD

    2012-09-01

    Full Text Available The Internet is increasingly used as a tool in qualitative research. In particular, asynchronous online focus groups are used when factors such as cost, time, or access to participants can make conducting face-to-face research difficult. In this article we consider key methodological issues involved in using asynchronous online focus groups to explore experiences of health and illness. The written nature of Internet communication, the lack of physical presence, and the asynchronous, longitudinal aspects enable participants who might not normally contribute to research studies to reflect on their personal stories before disclosing them to the researcher. Implications for study design, recruitment strategies, and ethics should be considered when deciding whether to use this method.

  5. Estimation of Threshold for the Signals of the BLMs around the LHC Final Focus Triplet Magnets

    CERN Document Server

    Cerutti, F; Ferrari, A; Hoa, C; Mauri, M; Mereghetti, A; Sapinski, M; Wildner, E; CERN. Geneva. ATS Department

    2012-01-01

    The Interaction Points of the Large Hadron Collider are the regions where the two circulating beams collide. Hence, the magnets the closest to any Interaction Point are exposed to an elevated radiation field due to the collision debris. In this study the signal in the Beam Loss Monitors due to the debris is estimated. In addition, for three different scenarios of beam losses, the energy density in the coils and the signal in the Beam Loss Monitors at quench are computed. It is shown that the Beam Loss Monitors, as presently installed on the vacuum vessel of the magnets, cannot disentangle the signal due to a localised loss from the constant signal due to the debris in case of steady-state losses.

  6. Pin cushion plasmonic device for polarization beam splitting, focusing, and beam position estimation.

    Science.gov (United States)

    Lerman, Gilad M; Levy, Uriel

    2013-03-13

    Great hopes rest on surface plasmon polaritons' (SPPs) potential to bring new functionalities and applications into various branches of optics. In this paper, we demonstrate a pin cushion structure capable of coupling light from free space into SPPs, split them based on the polarization content of the illuminating beam of light, and focus them into small spots. We also show that for a circularly or randomly polarized light, four focal spots will be generated at the center of each quarter circle comprising the pin cushion device. Furthermore, following the relation between the relative intensity of the obtained four focal spots and the relative position of the illuminating beam with respect to the structure, we propose and demonstrate the potential use of our structure as a miniaturized plasmonic version of the well-known four quadrant detector. Additional potential applications may vary from multichannel microscopy and multioptical traps to real time beam tracking systems.

  7. Ten Reasons to Still Keep the Focus on Teen Childbearing. Research Brief, Publication #2009-10

    Science.gov (United States)

    Holcombe, Emily; Peterson, Kristen; Manlove, Jennifer; Scarupa, Harriet J., Ed.

    2009-01-01

    In 2002, Child Trends drew on statistics and research findings to produce a report called "Ten Reasons to Keep the Focus on Teen Childbearing." That report took note of the steady decline in the nation's teenage pregnancy and childbearing rates, beginning in 1991, while citing multiple reasons to continue to be concerned about teen childbearing.…

  8. Broadening the focus of bat conservation and research in the USA for the 21st century

    Science.gov (United States)

    Theodore Weller; Paul Cryan; O’Shea Thomas

    2009-01-01

    Appropriately, bat conservation in the USA during the 20th century focused on species that tend to aggregate in large numbers and locations (e.g. maternity roosts, hibernacula) where populations are most vulnerable. Extensive research into habitat needs (primarily for roosting) of reproductive females during the previous 2 decades has produced a wealth of information...

  9. A Program to Improve Student Engagement at Research-Focused Universities

    Science.gov (United States)

    Whillans, Ashley V.; Hope, Sally E.; Wylie, Lauren J.; Zhao, Bob; Souza, Michael J.

    2018-01-01

    Promoting undergraduate engagement is an important and challenging obstacle at large research-focused universities. Thus, the current study evaluated whether a peer-led program of student-geared events could improve engagement among a diverse group of psychology students early on in their degrees. We randomly assigned interested second-year…

  10. Focus on CSIR research in pollution and waste: Integrated waste management

    CSIR Research Space (South Africa)

    Godfrey, Linda K

    2007-08-01

    Full Text Available Research into integrated waste management is undertaken in view of the impact of increasing populations and a strong national focus on industrial, agricultural and urban growth that is likely to result in the increase of human induced pressures...

  11. Teachers' Commitment To, and Experiences of, the Teaching Profession in Tanzania: Findings of Focus Group Research

    Science.gov (United States)

    Mkumbo, Kitila A. K.

    2012-01-01

    This qualitative study examined teachers' commitment to, and experiences of, the teaching profession in six regions of Tanzania. The study used focus group discussions as research method and data collection tool. Twenty four groups were conducted, with group membership ranging from five to nine participants. The results show that the teachers'…

  12. Risk of vicarious trauma in nursing research: a focused mapping review and synthesis.

    Science.gov (United States)

    Taylor, Julie; Bradbury-Jones, Caroline; Breckenridge, Jenna P; Jones, Christine; Herber, Oliver Rudolf

    2016-10-01

    To provide a snapshot of how vicarious trauma is considered within the published nursing research literature. Vicarious trauma (secondary traumatic stress) has been the focus of attention in nursing practice for many years. The most pertinent areas to invoke vicarious trauma in research have been suggested as abuse/violence and death/dying. What is not known is how researchers account for the risks of vicarious trauma in research. Focused mapping review and synthesis. Empirical studies meeting criteria for abuse/violence or death/dying in relevant Scopus ranked top nursing journals (n = 6) January 2009 to December 2014. Relevant papers were scrutinised for the extent to which researchers discussed the risk of vicarious trauma. Aspects of the studies were mapped systematically to a pre-defined template, allowing patterns and gaps in authors' reporting to be determined. These were synthesised into a coherent profile of current reporting practices and from this, a new conceptualisation seeking to anticipate and address the risk of vicarious trauma was developed. Two thousand five hundred and three papers were published during the review period, of which 104 met the inclusion criteria. Studies were distributed evenly by method (52 qualitative; 51 quantitative; one mixed methods) and by focus (54 abuse/violence; 50 death/dying). The majority of studies (98) were carried out in adult populations. Only two papers reported on vicarious trauma. The conceptualisation of vicarious trauma takes account of both sensitivity of the substantive data collected, and closeness of those involved with the research. This might assist researchers in designing ethical and protective research and foreground the importance of managing risks of vicarious trauma. Vicarious trauma is not well considered in research into clinically important topics. Our proposed framework allows for consideration of these so that precautionary measures can be put in place to minimise harm to staff. © 2016

  13. Genetic parameter and breeding value estimation of donkeys' problem-focused coping styles.

    Science.gov (United States)

    Navas González, Francisco Javier; Jordana Vidal, Jordi; León Jurado, José Manuel; Arando Arbulu, Ander; McLean, Amy Katherine; Delgado Bermejo, Juan Vicente

    2018-05-12

    Donkeys are recognized therapy or leisure-riding animals. Anecdotal evidence has suggested that more reactive donkeys or those more easily engaging flight mechanisms tend to be easier to train compared to those displaying the natural donkey behaviour of fight. This context brings together the need to quantify such traits and to genetically select donkeys displaying a neutral reaction during training, because of its implication with handler/rider safety and trainability. We analysed the scores for coping style traits from 300 Andalusian donkeys from 2013 to 2015. Three scales were applied to describe donkeys' response to 12 stimuli. Genetic parameters were estimated using multivariate models with year, sex, husbandry system and stimulus as fixed effects and age as a linear and quadratic covariable. Heritabilities were moderate, 0.18 ± 0.020 to 0.21 ± 0.021. Phenotypic correlations between intensity and mood/emotion or response type were negative and moderate (-0.21 and -0.25, respectively). Genetic correlations between the same variables were negative and moderately high (-0.46 and -0.53, respectively). Phenotypic and genetic correlations between mood/emotion and response type were positive and high (0.92 and 0.95, respectively). Breeding values enable selection methods that could lead to endangered breed preservation and genetically selecting donkeys for the uses that they may be most suitable. Copyright © 2018 Elsevier B.V. All rights reserved.

  14. Design and Fabrication of Solar Updraft Tower and Estimation of Power Generation; Initially Focused on Bangladesh

    Science.gov (United States)

    Ayub, F.; Akhand, S.; Khan, A. S.; Saklayen, G.

    2018-05-01

    In our studies we focused on area of sourcing, converting and delivering sustainable energy, concentrating at the potential role of solar power. Power generation through a solar updraft tower (SUT) has been a promising approach for sustainable generation of renewable energy. Developing nations are faced with many challenges. Conventional sources are insufficient to meet the increasing demand of a developing, industrious nation (e.g. Bangladesh). Our project aims in reducing electricity crisis and forming a solution for our country, Bangladesh. The electricity generated can be supplied to the national grid. This will mean reduced cost for the government in the long run and also allow the government to reduce its dependency on costly and unsustainable fossil fuel. This cost reduction benefit can be passed on to the public as reduced energy cost or preferably through nationwide energy infrastructure development. This technology will not only help with the energy concern of Bangladesh but also will help to improve the situations of other developing countries alike Bangladesh. All in all implementing this technology will pave the way towards a better world and form a part of an integrated ecosystem of sustainable energy technology.

  15. Multivariate return periods in hydrology: a critical and practical review focusing on synthetic design hydrograph estimation

    Directory of Open Access Journals (Sweden)

    B. Gräler

    2013-04-01

    Full Text Available Most of the hydrological and hydraulic studies refer to the notion of a return period to quantify design variables. When dealing with multiple design variables, the well-known univariate statistical analysis is no longer satisfactory, and several issues challenge the practitioner. How should one incorporate the dependence between variables? How should a multivariate return period be defined and applied in order to yield a proper design event? In this study an overview of the state of the art for estimating multivariate design events is given and the different approaches are compared. The construction of multivariate distribution functions is done through the use of copulas, given their practicality in multivariate frequency analyses and their ability to model numerous types of dependence structures in a flexible way. A synthetic case study is used to generate a large data set of simulated discharges that is used for illustrating the effect of different modelling choices on the design events. Based on different uni- and multivariate approaches, the design hydrograph characteristics of a 3-D phenomenon composed of annual maximum peak discharge, its volume, and duration are derived. These approaches are based on regression analysis, bivariate conditional distributions, bivariate joint distributions and Kendall distribution functions, highlighting theoretical and practical issues of multivariate frequency analysis. Also an ensemble-based approach is presented. For a given design return period, the approach chosen clearly affects the calculated design event, and much attention should be given to the choice of the approach used as this depends on the real-world problem at hand.

  16. The Impact of Natural Disasters on Youth: A Focus on Emerging Research beyond Internalizing Disorders.

    Science.gov (United States)

    Self-Brown, Shannon; Lai, Betty; Patterson, Alexandria; Glasheen, Theresa

    2017-08-01

    This paper reviews youth outcomes following exposure to natural disaster, with a focus on three relatively understudied outcomes: externalizing behavior problems, physical health, and posttraumatic growth. Recent, high-impact studies focusing on each outcome are summarized. Studies highlighted in this review utilize innovative and comprehensive approaches to improve our current understanding of youth broad-based physical and mental health outcomes beyond PTSD. The review concludes with recommendations to advance the field of youth disaster research by exploring how disasters may impact children across multiple domains, as well as using cutting edge ecobiological approaches and advanced modeling strategies to better understand how youth adjust and thrive following natural disaster.

  17. Patient informed governance of distributed research networks: results and discussion from six patient focus groups.

    Science.gov (United States)

    Mamo, Laura A; Browe, Dennis K; Logan, Holly C; Kim, Katherine K

    2013-01-01

    Understanding how to govern emerging distributed research networks is essential to their success. Distributed research networks aggregate patient medical data from many institutions leaving data within the local provider security system. While much is known about patients' views on secondary medical research, little is known about their views on governance of research networks. We conducted six focus groups with patients from three medical centers across the U.S. to understand their perspectives on privacy, consent, and ethical concerns of sharing their data as part of research networks. Participants positively endorsed sharing their health data with these networks believing that doing so could advance healthcare knowledge. However, patients expressed several concerns regarding security and broader ethical issues such as commercialism, public benefit, and social responsibility. We suggest that network governance guidelines move beyond strict technical requirements and address wider socio-ethical concerns by fully including patients in governance processes.

  18. Research reactor loading pattern optimization using estimation of distribution algorithms

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, S. [Dept. of Earth Science and Engineering, Applied Modeling and Computation Group AMCG, Imperial College, London, SW7 2AZ (United Kingdom); Ziver, K. [Dept. of Earth Science and Engineering, Applied Modeling and Computation Group AMCG, Imperial College, London, SW7 2AZ (United Kingdom); AMCG Group, RM Consultants, Abingdon (United Kingdom); Carter, J. N.; Pain, C. C.; Eaton, M. D.; Goddard, A. J. H. [Dept. of Earth Science and Engineering, Applied Modeling and Computation Group AMCG, Imperial College, London, SW7 2AZ (United Kingdom); Franklin, S. J.; Phillips, H. J. [Imperial College, Reactor Centre, Silwood Park, Buckhurst Road, Ascot, Berkshire, SL5 7TE (United Kingdom)

    2006-07-01

    A new evolutionary search based approach for solving the nuclear reactor loading pattern optimization problems is presented based on the Estimation of Distribution Algorithms. The optimization technique developed is then applied to the maximization of the effective multiplication factor (K{sub eff}) of the Imperial College CONSORT research reactor (the last remaining civilian research reactor in the United Kingdom). A new elitism-guided searching strategy has been developed and applied to improve the local convergence together with some problem-dependent information based on the 'stand-alone K{sub eff} with fuel coupling calculations. A comparison study between the EDAs and a Genetic Algorithm with Heuristic Tie Breaking Crossover operator has shown that the new algorithm is efficient and robust. (authors)

  19. Research reactor loading pattern optimization using estimation of distribution algorithms

    International Nuclear Information System (INIS)

    Jiang, S.; Ziver, K.; Carter, J. N.; Pain, C. C.; Eaton, M. D.; Goddard, A. J. H.; Franklin, S. J.; Phillips, H. J.

    2006-01-01

    A new evolutionary search based approach for solving the nuclear reactor loading pattern optimization problems is presented based on the Estimation of Distribution Algorithms. The optimization technique developed is then applied to the maximization of the effective multiplication factor (K eff ) of the Imperial College CONSORT research reactor (the last remaining civilian research reactor in the United Kingdom). A new elitism-guided searching strategy has been developed and applied to improve the local convergence together with some problem-dependent information based on the 'stand-alone K eff with fuel coupling calculations. A comparison study between the EDAs and a Genetic Algorithm with Heuristic Tie Breaking Crossover operator has shown that the new algorithm is efficient and robust. (authors)

  20. Online Facebook Focus Group Research of Hard-to-Reach Participants

    Directory of Open Access Journals (Sweden)

    Anastasia Aldelina Lijadi

    2015-12-01

    Full Text Available Conducting discovery-oriented qualitative research about the life experiences of hard-to-reach individuals posed several challenges for recruiting participants and collecting rich textual data. In a study pertaining the experiences of Third Culture Kids (TCKs, we explored the benefits of the social media, such as Facebook as a platform to collect data. TCKs are individuals who define their sense of belonging to the third culture trailing their parents moving across borders during their developmental years. Adult TCKs live in many different countries, and accessing and interviewing respondents could be a difficult and costly endeavor. In this article, the authors share their experience conducting online, asynchronous focus groups using a Facebook platform. We reflect upon the process of setting up a secret Facebook focus group for research purposes, recruiting participants, rapport building between facilitator and participants, monitoring and keeping track of participants’ responses, and the dynamics emerging within an online focus group. We also discuss the novelty, limitations, and benefits of the Facebook focus group as an emerging mode for collecting qualitative data from hard-to-reach participants.

  1. Future Deltas Utrecht University research focus area: towards sustainable management of sinking deltas

    Science.gov (United States)

    Stouthamer, E.; van Asselen, S.

    2015-11-01

    Deltas are increasingly under pressure from human impact and climate change. To deal with these pressures that threat future delta functioning, we need to understand interactions between physical, biological, chemical and social processes in deltas. This requires an integrated approach, in which knowledge on natural system functioning is combined with knowledge on spatial planning, land and water governance and legislative frameworks. In the research focus area Future Deltas of Utrecht University an interdisciplinary team from different research groups therefore works together. This allows developing integrated sustainable and resilient delta management strategies, which is urgently needed to prevent loss of vital delta services.

  2. The use of Facebook for virtual asynchronous focus groups in qualitative research.

    Science.gov (United States)

    Biedermann, Narelle

    2018-02-01

    The Internet and the development of more user-engaging applications have opened a whole new world for researchers as a means of recruitment and data collection source. This paper describes the methodological approach of a research study that explored the experiences of Australian military spouses who packed up their family and home to accompany their spouse on an overseas posting. The study used Facebook as a recruitment tool and then as a data source through the conduct of an asynchronous virtual focus group. This paper outlines the advantages and disadvantages of this unique data source as a means of capturing the voices of a hard-to-reach population.

  3. What should autism research focus upon? Community views and priorities from the United Kingdom

    Science.gov (United States)

    Dinsmore, Adam; Charman, Tony

    2014-01-01

    The rise in the measured prevalence of autism has been accompanied by much new research and research investment internationally. This study sought to establish whether the pattern of current UK autism research funding maps on to the concerns of the autism community. Interviews and focus groups were conducted with autistic adults, family members, practitioners and researchers to identify their priorities for research. We also captured the views of a large number of stakeholders via an online survey. There was a clear disparity between the United Kingdom’s pattern of funding for autism research and the priorities articulated by the majority of participants. There was general consensus that future priorities for autism research should lie in those areas that make a difference to people’s day-to-day lives. There needs to be greater involvement of the autism community both in priority setting and in research more broadly to ensure that resources reach where they are most needed and can make the most impact. PMID:24789871

  4. Distributed and grid computing projects with research focus in human health.

    Science.gov (United States)

    Diomidous, Marianna; Zikos, Dimitrios

    2012-01-01

    Distributed systems and grid computing systems are used to connect several computers to obtain a higher level of performance, in order to solve a problem. During the last decade, projects use the World Wide Web to aggregate individuals' CPU power for research purposes. This paper presents the existing active large scale distributed and grid computing projects with research focus in human health. There have been found and presented 11 active projects with more than 2000 Processing Units (PUs) each. The research focus for most of them is molecular biology and, specifically on understanding or predicting protein structure through simulation, comparing proteins, genomic analysis for disease provoking genes and drug design. Though not in all cases explicitly stated, common target diseases include research to find cure against HIV, dengue, Duchene dystrophy, Parkinson's disease, various types of cancer and influenza. Other diseases include malaria, anthrax, Alzheimer's disease. The need for national initiatives and European Collaboration for larger scale projects is stressed, to raise the awareness of citizens to participate in order to create a culture of internet volunteering altruism.

  5. Linking research and education: an undergraduate research apprenticeship focusing on geologic and ecological impacts of the Elwha River Restoration

    Science.gov (United States)

    Ogston, A. S.; Eidam, E.; Webster, K. L.; Hale, R. P.

    2016-02-01

    Experiential learning is becoming well-rooted in undergraduate curriculum as a means of stimulating interest in STEM fields, and of preparing students for future careers in scientific research and communication. To further these goals in coastal sciences, an intensive, research-focused course was developed at the UW Friday Harbor Labs. The course revolved around an active NSF-funded research project concerning the highly publicized Elwha River Restoration project. Between 2008 and 2014, four groups of research "apprentices" spent their academic quarter in residence at a small, coastal marine lab in a learning environment that integrated interdisciplinary lectures, workshops on data analysis and laboratory methods, and the research process from proposal to oceanographic research cruise to publication. This environment helped students gain important skills in fieldwork planning and execution, laboratory and digital data analyses, and manuscript preparation from start to finish—all while elevating their knowledge of integrated earth science topics related to a coastal restoration project. Students developed their own research proposals and pursued their individual interests within the overall research topic, thereby expanding the overall breadth of the NSF-funded research program. The topics of student interest were often beyond the researcher's expertise, which ultimately led to more interdisciplinary findings beyond the quarter-long class. This also provided opportunities for student creativity and leadership, and for collaboration with fellow course participants and with students from many other disciplines in residence at the marine lab. Tracking the outcomes of the diverse student group undertaking this program indicates that these undergraduate (and post-bac) students are generally attending graduate school at a high rate, and launching careers in education, coastal management, and other STEM fields.

  6. Indicators of national focus of the research published by Public Health journals edited in Brazil.

    Science.gov (United States)

    Packer, Abel Laerte

    2015-07-01

    This report presents a set of bibliometric indicators and statistics which explain the high level of production of articles on research in public and collective health in Brazil which are published in the main nationally edited journals in the field. The predominance of publications in the Portuguese language by Brazilian authors results in a lower impact in terms of citations received as measured by the bibliometric indexes Scimago/Scopus and JCR/WoS. These bibliometric indexes are used to measure the production and performance of research and journals. Nevertheless, the performance of these same journals stands out in SciELO, and is competitive internationally in the broader context of Google Scholar Metrics. The challenge faced by journals in Brazil is developing and applying editorial policies for the valuation of research with a national focus, and its internationalization.

  7. Shifting the focus from quantitative to qualitative exercise characteristics in exercise and cognition research.

    Science.gov (United States)

    Pesce, Caterina

    2012-12-01

    In exercise and cognition research, few studies have investigated whether and how the qualitative aspects of physical exercise may impact cognitive performance in the short or long term. This commentary, after recalling the evidence on the "dose-response" relationship, shifts the focus to intersections between different research areas that are proposed to shed light on how qualitative exercise characteristics can be used to obtain cognitive benefits. As concerns the acute exercise area, this commentary highlights the applied relevance of developmental and aging studies investigating the effects of exercise bouts differing in movement task complexity and cognitive demands. As regards the chronic exercise area, potential links to research on cognitive expertise in sport, functional ability in aging, and life skills training during development are discussed. "Gross-motor cognitive training" is proposed as a key concept with relevant implications for intervention strategies in childhood and older adulthood.

  8. Developing a plasma focus research training system for the fusion energy age

    International Nuclear Information System (INIS)

    Lee, S.

    2014-01-01

    The 3 kJ UNU/ICTP Plasma Focus Facility is the most significant device associated with the AAAPT (Asian African Association for Plasma Training). In original and modified/upgraded form it has trained generations of plasma focus (PF) researchers internationally, producing many PhD theses and peer-reviewed papers. The Lee Model code was developed for the design of this PF. This code has evolved to cover all PF machines for design, interpretation and optimization, for derivation of radiation scaling laws; and to provide insights into yield scaling limitations, radiative collapse, speed-enhanced and current-stepped PF variants. As example of fresh perspectives derivable from this code, this paper presents new results on energy transfers of the axial and radial phases of generalized PF devices. As the world moves inexorably towards the Fusion Energy Age it becomes ever more important to train plasma fusion researchers. A recent workshop in Nepal shows that demand for such training continues. Even commercial project development consultants are showing interest. We propose that the AAAPT-proven research package be upgraded, by modernizing the small PF for extreme modes of operation, switchable from the typical strong-focus mode to a slow-mode which barely pinches, thus producing a larger, more uniform plasma stream with superior deposition properties. Such a small device would be cost-effective and easily duplicated, and have the versatility of a range of experiments from intense multi-radiation generation and target damage studies to superior advanced-materials deposition. The complementary code is used to reference experiments up to the largest existing machine. This is ideal for studying machine limitations and scaling laws and to suggest new experiments. Such a modernized versatile PF machine complemented by the universally versatile code would extend the utility of the PF experience; so that AAAPT continues to provide leadership in pulsed plasma research training in

  9. Integrating utilization-focused evaluation with business process modeling for clinical research improvement.

    Science.gov (United States)

    Kagan, Jonathan M; Rosas, Scott; Trochim, William M K

    2010-10-01

    New discoveries in basic science are creating extraordinary opportunities to design novel biomedical preventions and therapeutics for human disease. But the clinical evaluation of these new interventions is, in many instances, being hindered by a variety of legal, regulatory, policy and operational factors, few of which enhance research quality, the safety of study participants or research ethics. With the goal of helping increase the efficiency and effectiveness of clinical research, we have examined how the integration of utilization-focused evaluation with elements of business process modeling can reveal opportunities for systematic improvements in clinical research. Using data from the NIH global HIV/AIDS clinical trials networks, we analyzed the absolute and relative times required to traverse defined phases associated with specific activities within the clinical protocol lifecycle. Using simple median duration and Kaplan-Meyer survival analysis, we show how such time-based analyses can provide a rationale for the prioritization of research process analysis and re-engineering, as well as a means for statistically assessing the impact of policy modifications, resource utilization, re-engineered processes and best practices. Successfully applied, this approach can help researchers be more efficient in capitalizing on new science to speed the development of improved interventions for human disease.

  10. Technology Estimating: A Process to Determine the Cost and Schedule of Space Technology Research and Development

    Science.gov (United States)

    Cole, Stuart K.; Reeves, John D.; Williams-Byrd, Julie A.; Greenberg, Marc; Comstock, Doug; Olds, John R.; Wallace, Jon; DePasquale, Dominic; Schaffer, Mark

    2013-01-01

    NASA is investing in new technologies that include 14 primary technology roadmap areas, and aeronautics. Understanding the cost for research and development of these technologies and the time it takes to increase the maturity of the technology is important to the support of the ongoing and future NASA missions. Overall, technology estimating may help provide guidance to technology investment strategies to help improve evaluation of technology affordability, and aid in decision support. The research provides a summary of the framework development of a Technology Estimating process where four technology roadmap areas were selected to be studied. The framework includes definition of terms, discussion for narrowing the focus from 14 NASA Technology Roadmap areas to four, and further refinement to include technologies, TRL range of 2 to 6. Included in this paper is a discussion to address the evaluation of 20 unique technology parameters that were initially identified, evaluated and then subsequently reduced for use in characterizing these technologies. A discussion of data acquisition effort and criteria established for data quality are provided. The findings obtained during the research included gaps identified, and a description of a spreadsheet-based estimating tool initiated as a part of the Technology Estimating process.

  11. Using the Human Systems Simulation Laboratory at Idaho National Laboratory for Safety Focused Research

    Energy Technology Data Exchange (ETDEWEB)

    Joe, Jeffrey .C; Boring, Ronald L.

    2016-07-01

    Under the United States (U.S.) Department of Energy (DOE) Light Water Reactor Sustainability (LWRS) program, researchers at Idaho National Laboratory (INL) have been using the Human Systems Simulation Laboratory (HSSL) to conduct critical safety focused Human Factors research and development (R&D) for the nuclear industry. The LWRS program has the overall objective to develop the scientific basis to extend existing nuclear power plant (NPP) operating life beyond the current 60-year licensing period and to ensure their long-term reliability, productivity, safety, and security. One focus area for LWRS is the NPP main control room (MCR), because many of the instrumentation and control (I&C) system technologies installed in the MCR, while highly reliable and safe, are now difficult to replace and are therefore limiting the operating life of the NPP. This paper describes how INL researchers use the HSSL to conduct Human Factors R&D on modernizing or upgrading these I&C systems in a step-wise manner, and how the HSSL has addressed a significant gap in how to upgrade systems and technologies that are built to last, and therefore require careful integration of analog and new advanced digital technologies.

  12. Research on health equity in the SDG era: the urgent need for greater focus on implementation.

    Science.gov (United States)

    Rasanathan, Kumanan; Diaz, Theresa

    2016-12-09

    The tremendous increase in knowledge on inequities in health and their drivers in recent decades has not been matched by improvements in health inequities themselves, or by systematic evidence of what works to reduce health inequities. Within health equity research there is a skew towards diagnostic studies in comparison to intervention studies showing evidence of how interventions can reduce disparities. The lack of sufficient specific evidence on how to implement specific policies and interventions in specific contexts to reduce health inequities creates policy confusion and partly explains the lack of progress on health inequities. In the field of research on equity in health, the time has come to stop focusing so much energy on prevalence and pathways, and instead shift to proposing and testing solutions. Four promising approaches to do so are implementation research, natural experimental policy studies, research on buy-in by policy-makers to action on health inequities, and geospatial analysis. The case for action on social determinants and health inequities has well and truly been made. The community of researchers on health equity now need to turn their attention to supporting implementation efforts towards achievements of the Sustainable Development Goals and substantive reductions in health inequities.

  13. How much are we spending? The estimation of research expenditures on cardiovascular disease in Canada

    Science.gov (United States)

    2012-01-01

    Background Cardiovascular disease (CVD) is a leading cause of death in Canada and is a priority area for medical research. The research funding landscape in Canada has changed quite a bit over the last few decades, as have funding levels. Our objective was to estimate the magnitude of expenditures on CVD research for the public and charitable (not-for profit) sectors in Canada between 1975 and 2005. Methods To estimate research expenditures for the public and charitable sectors, we compiled a complete list of granting agencies in Canada, contacted each agency and the Canadian Institutes of Health Research (CIHR), and extracted data from the organizations’ annual reports and the Reference Lists of health research in Canada. Two independent reviewers scanned all grant and fellowship/scholarship titles (and summary/key words, when available) of all research projects funded to determine their inclusion in our analysis; only grants and fellowships/scholarships that focused on heart and peripheral vascular diseases were selected. Results Public/charitable sector funding increased 7.5 times, from close to $13 million (in constant dollars) in 1975 to almost $96 million (in constant dollars) in 2005 (base year). The Medical Research Council of Canada (MRCC)/CIHR and the Heart & Stroke Foundation of Canada have been the main founders of this type of research during our analysis period; the Alberta Heritage Foundation for Medical Research and the Fonds de la recherche en santé du Quebec have played major roles at the provincial level. The Indirect Costs Research Program and Canada Foundation for Innovation have played major roles in terms of funding in the last years of our analysis. Conclusion Public/charitable-funded research expenditures devoted to CVD have increased substantially over the last three decades. By international standards, the evidence suggests Canada spends less on health-related research than the UK and the US, at least in absolute terms. However, this

  14. Technology Estimating 2: A Process to Determine the Cost and Schedule of Space Technology Research and Development

    Science.gov (United States)

    Cole, Stuart K.; Wallace, Jon; Schaffer, Mark; May, M. Scott; Greenberg, Marc W.

    2014-01-01

    As a leader in space technology research and development, NASA is continuing in the development of the Technology Estimating process, initiated in 2012, for estimating the cost and schedule of low maturity technology research and development, where the Technology Readiness Level is less than TRL 6. NASA' s Technology Roadmap areas consist of 14 technology areas. The focus of this continuing Technology Estimating effort included four Technology Areas (TA): TA3 Space Power and Energy Storage, TA4 Robotics, TA8 Instruments, and TA12 Materials, to confine the research to the most abundant data pool. This research report continues the development of technology estimating efforts completed during 2013-2014, and addresses the refinement of parameters selected and recommended for use in the estimating process, where the parameters developed are applicable to Cost Estimating Relationships (CERs) used in the parametric cost estimating analysis. This research addresses the architecture for administration of the Technology Cost and Scheduling Estimating tool, the parameters suggested for computer software adjunct to any technology area, and the identification of gaps in the Technology Estimating process.

  15. Healthy lifestyle: Perceptions and attitudes of students (the results of a focus group research

    Directory of Open Access Journals (Sweden)

    Zh V Puzanova

    2014-12-01

    Full Text Available The article presents the results of the research conducted in December 2013 at the Peoples’ Friendship University of Russia with the method of focus groups. The study aimed at identification not only the differences in understanding healthy lifestyles among students and their attitudes to a healthy lifestyle, but also its components, obstacles for the realization and opportunities to overcome them. The focus group research was just another stage of the project aimed at studying health and healthy lifestyles as values and the characteristics of the formation and manifestation of a health-preserving behavior. Despite many opportunities to motivate a health-preserving behavior among students, we still see obstacles for its formation due to both social and cultural characteristics. The study revealed that the value of health at this stage of life is rather declarative: only a small percentage of respondents are fully aware of the necessity of a health-preserving behavior and do really adopt a healthy lifestyle. The basic factors influencing the formation of the healthy lifestyle among the youth are the family, social environment and mass media. The respondents, in particular, confirm the significant impact of their social circle on the commitment to the bad habits as well as to healthy hobbies. The main factors hindering the healthy lifestyles among students include lack of free time, welfare, Internet addiction, lack of sufficient motivation and self-organization.

  16. Family-Focused Therapy for Bipolar Disorder: Reflections on 30 Years of Research.

    Science.gov (United States)

    Miklowitz, David J; Chung, Bowen

    2016-09-01

    Family-focused therapy (FFT) is an evidence-based intervention for adults and children with bipolar disorder (BD) and their caregivers, usually given in conjunction with pharmacotherapy after an illness episode. The treatment consists of conjoint sessions of psychoeducation regarding bipolar illness, communication enhancement training, and problem-solving skills training. This paper summarizes over 30 years of research on FFT and family processes in BD. Across eight randomized controlled trials with adults and adolescents with BD, FFT and mood-stabilizing medications have been found to hasten recovery from mood episodes, reduce recurrences, and reduce levels of symptom severity compared to briefer forms of psychoeducation and medications over 1-2 years. Several studies indicate that the effects of FFT on symptom improvement are greater among patients with high-expressed emotion relatives. New research focuses on FFT as an early intervention for youth at risk for BD, neuroimaging as a means of evaluating treatment mechanisms, and progress in implementing FFT in community mental health settings. © 2016 Family Process Institute.

  17. The social process of escalation: a promising focus for crisis management research

    Directory of Open Access Journals (Sweden)

    Bergström Johan

    2012-06-01

    Full Text Available Abstract Background This study identifies a promising, new focus for the crisis management research in the health care domain. After reviewing the literature on health care crisis management, there seems to be a knowledge-gap regarding organisational change and adaption, especially when health care situations goes from normal, to non-normal, to pathological and further into a state of emergency or crisis. Discussion Based on studies of escalating situations in obstetric care it is suggested that two theoretical perspectives (contingency theory and the idea of failure as a result of incomplete interaction tend to simplify the issue of escalation rather than attend to its complexities (including the various power relations among the stakeholders involved. However studying the process of escalation as inherently complex and social allows us to see the definition of a situation as normal or non-normal as an exercise of power in itself, rather than representing a putatively correct response to a particular emergency. Implications The concept of escalation, when treated this way, can help us further the analysis of clinical and institutional acts and competence. It can also turn our attention to some important elements in a class of social phenomenon, crises and emergencies, that so far have not received the attention they deserve. Focusing on organisational choreography, that interplay of potential factors such as power, professional identity, organisational accountability, and experience, is not only a promising focus for future naturalistic research but also for developing more pragmatic strategies that can enhance organisational coordination and response in complex events.

  18. Towards a new understanding of cohabitation: Insights from focus group research across Europe and Australia

    Directory of Open Access Journals (Sweden)

    Brienna Perelli-Harris

    2014-11-01

    Full Text Available Background: Across the industrialized world, more couples are living together without marrying. Although researchers have compared cohabitation cross-nationally using quantitative data, few have compared union formation using qualitative data. Objective: We use focus group research to compare social norms of cohabitation and marriage in Australia and nine countries in Europe. We explore questions such as: what is the meaning of cohabitation? To what extent is cohabitation indistinguishable from marriage, a prelude to marriage, or an alternative to being single? Are the meanings of cohabitation similar across countries? Methods: Collaborators conducted seven to eight focus groups in each country using a standardized guideline. They analyzed the discussions with bottom-up coding in each thematic area. They then collated the data in a standardized report. The first and second authors systematically analyzed the reports, with direct input from collaborators. Results: The results describe a specific picture of union formation in each country. However, three themes emerge in all focus groups: commitment, testing, and freedom. The pervasiveness of these concepts suggests that marriage and cohabitation have distinct meanings, with marriage representing a stronger level of commitment. Cohabitation is a way to test the relationship, and represents freedom. Nonetheless, other discourses emerged, suggesting that cohabitation has multiple meanings. Conclusions: This study illuminates how context shapes partnership formation, but also presents underlying reasons for the development of cohabitation. We find that the increase in cohabitation has not devalued the concept of marriage, but has become a way to preserve marriage as an ideal for long-term commitment.

  19. Outlining and dictating scientific manuscripts is a useful method for health researchers: A focus group interview.

    Science.gov (United States)

    Andresen, Kristoffer; Laursen, Jannie; Rosenberg, Jacob

    2018-01-01

    Young researchers may experience difficulties when writing scientific articles for publication in biomedical journals. Various methods may facilitate the writing process including outlining the paper before the actual writing and using dictation instead of writing the first draft. The aim of this study was to investigate the experiences and difficulties for young, experienced researchers when writing articles using a detailed outline and dictation of the first draft. We used qualitative focus group interviews and the study was reported according to the COnsolidated criteria for REporting Qualitative research guideline. Participants were sampled from a group of researchers participating in a writing retreat/course. The interviews were recorded on a digital recorder and transcribed. The text was analyzed according to content analysis and coded and condensed into themes and subthemes. Groups of participants were added until data saturation was reached. A total of 14 researchers participated (9 women and 5 men). Their clinical experience was median (range) of 6 (1-11) years since graduation from medical school. Two themes arose during the analyses of the data: "Process guidance with the outline as the map" and "arrival at dictation." The outline was used in the preparation phase leading up to the day of dictation and was used in collaboration with co-authors and supervisors. The participants found it to be a useful tool for preparing the manuscript and dictating their initial first full draft. Experienced young researchers found beneficial effects of using a structured outline to prepare for dictation of scientific articles. The outline was a tool that would develop in close collaboration with co-authors and mentors. With dictation, a full first draft of a manuscript can be produced in a few hours. Participants positively evaluated this structured and reproducible way of producing scientific articles.

  20. The possible worlds of global health research: An ethics-focused discourse analysis.

    Science.gov (United States)

    Brisbois, Ben; Plamondon, Katrina

    2018-01-01

    Representations of the world enable global health research (GHR), discursively constructing sites in which studies can legitimately take place. Depoliticized portrayals of the global South frequently obscure messy legacies of colonialism and motivate technical responses to health problems with political and economic root causes. Such problematic representations of the world have not yet been rigorously examined in relation to global health ethics, a major site of scholarly effort towards GHR that promotes justice and fairness. We carried out a discourse analysis of four guidance documents relevant to the ethical practice of GHR, purposively selecting texts covering different genres (UN documents and journal articles) and prominent GHR foci (HIV and clinical trials). In light of increasing acknowledgement of the lessons Indigenous health scholarship holds for global health ethics, the four analyzed texts also included a set of principles developed to support Indigenous nation-building. Three of four documents featured global disparities as reasons for ethical caution. These inequalities appeared without explanation or causes, with generation of new scientific knowledge following as a logical response to such disparities. The fourth - Indigenous health-focused - document clearly identified 'colonialism' as a reason for both inequities in society, and related harmful research practices. Solutions to disparities in this text did not necessarily involve cutting-edge research, but focused instead on empowerment and responsiveness to community priorities and needs. These contrasting representations of the world were accomplished in ways that depended on texts' 'participants', or the people they represented; specific vocabularies or language usages; intertextual relationships to prior texts; and overall objectives or intentions of the author(s). Our results illustrate how ethics and other guidance documents serve as an important terrain for constructing, naturalizing or

  1. Strategies for Sharing Scientific Research on Sea Level Rise: Suggestions from Stakeholder Focus Groups

    Science.gov (United States)

    DeLorme, D.; Hagen, S. C.; Stephens, S. H.

    2013-12-01

    This presentation reports results of focus groups with coastal resource managers on suggestions for effectively sharing sea level rise (SLR) scientific research with the public and other target audiences. The focus groups were conducted during three annual stakeholder workshops as an important and innovative component of an ongoing five-year multi-disciplinary NOAA-funded project, Ecological Effects of Sea Level Rise in the Northern Gulf of Mexico (EESLR-NGOM). The EESLR-NGOM project is assessing SLR risks to the natural and built environment along the Mississippi, Alabama, and Florida Panhandle coasts. The purpose was to engage stakeholders (e.g., coastal resource managers) in helping target, translate, and tailor the EESLR-NGOM project's scientific findings and emerging products so they are readily accessible, understandable, and useful. The focus groups provided insight into stakeholders' SLR informational and operational needs, solicited input on the project's products, and gathered suggestions for public communication and outreach. A total of three ninety-minute focus groups of between eight and thirteen participants each were conducted at annual workshops in Alabama, Florida, and Mississippi. The moderator asked a series of open-ended questions about SLR-related topics using an interview guide and encouraged participant interaction. All focus group audio-recordings were transcribed, and analyzed by carefully reading the 102 total pages of transcript data and identifying patterns and themes. Participants thought outreach about SLR impact and the EESLR-NGOM project scientific research/products was vital and acknowledged various communication challenges and opportunities. They identified three target audiences (local officials, general public, coastal resource managers themselves) that likely require different educational efforts and tools. Participants felt confident the EESLR-NGOM project products will benefit their resource planning and decision making and

  2. Dosimetry in radiotherapy using a-Si EPIDs: Systems, methods, and applications focusing on 3D patient dose estimation

    Science.gov (United States)

    McCurdy, B. M. C.

    2013-06-01

    An overview is provided of the use of amorphous silicon electronic portal imaging devices (EPIDs) for dosimetric purposes in radiation therapy, focusing on 3D patient dose estimation. EPIDs were originally developed to provide on-treatment radiological imaging to assist with patient setup, but there has also been a natural interest in using them as dosimeters since they use the megavoltage therapy beam to form images. The current generation of clinically available EPID technology, amorphous-silicon (a-Si) flat panel imagers, possess many characteristics that make them much better suited to dosimetric applications than earlier EPID technologies. Features such as linearity with dose/dose rate, high spatial resolution, realtime capability, minimal optical glare, and digital operation combine with the convenience of a compact, retractable detector system directly mounted on the linear accelerator to provide a system that is well-suited to dosimetric applications. This review will discuss clinically available a-Si EPID systems, highlighting dosimetric characteristics and remaining limitations. Methods for using EPIDs in dosimetry applications will be discussed. Dosimetric applications using a-Si EPIDs to estimate three-dimensional dose in the patient during treatment will be overviewed. Clinics throughout the world are implementing increasingly complex treatments such as dynamic intensity modulated radiation therapy and volumetric modulated arc therapy, as well as specialized treatment techniques using large doses per fraction and short treatment courses (ie. hypofractionation and stereotactic radiosurgery). These factors drive the continued strong interest in using EPIDs as dosimeters for patient treatment verification.

  3. Australian Aboriginal and Torres Strait Islander-focused primary healthcare social and emotional wellbeing research: a systematic review protocol.

    Science.gov (United States)

    Farnbach, Sara; Eades, Anne-Marie; Hackett, Maree Lisa

    2015-12-30

    Research with a focus on Aboriginal and Torres Strait Islander Australian's (hereafter referred to as Indigenous(1)) needs is crucial to ensure culturally appropriate evidence-based strategies are developed to improve health. However, concerns surrounding this research exist, arising from some previous research lacking community consultation, resulting in little community benefit or infringing on important cultural values. Values and Ethics: Guidelines for Ethical conduct in Aboriginal and Torres Strait Islander Health Research (hereafter referred to as Values and Ethics), developed by The National Health and Medical Research Council of Australia in 2003, is the ethical standard for Indigenous-focused health research. Researchers must address its Values in research design and conduct. However, its impact on research processes is unclear. Local Protocols should also be considered. This review aims to systematically examine practices related to Values and Ethics, Local Protocols and the processes of conducting Indigenous-focused primary healthcare research in collaboration with external researchers. The following electronic databases and grey literature will be searched (2003 to current): MEDLINE, EMBASE, CINAHL, Informit and HealthInfoNet--an Indigenous-specific research and program website. Indigenous-focused research will be included. Research must be conducted in one or more primary healthcare services, in collaboration with external researchers and with a focus on social and emotional well being. One reviewer will review titles and abstracts to remove obviously irrelevant research articles. Full-text research articles will be retrieved and independently examined by two reviewers. Data and quality assessment will be completed by one reviewer and verified by a second reviewer. Quality will be assessed using modified versions of established quality assessment tools. This review will provide information on research processes and the impact of Values and Ethics on

  4. Mapping patterns of change in emotion-focused psychotherapy: Implications for theory, research, practice, and training.

    Science.gov (United States)

    Watson, Jeanne C

    2018-05-01

    An important objective in humanistic-experiential psychotherapies and particularly emotion-focused psychotherapy (EFT) is to map patterns of change. Effective mapping of the processes and pathways of change requires that in-session processes be linked to in-session resolutions, immediate post-session changes, intermediate outcome, final therapy outcome, and longer-term change. This is a challenging and long-term endeavour. Fine-grained descriptions of in-session processes that lead to resolution of specific interpersonal and intrapersonal issues linked with longer-term outcomes are the foundation of EFT, the process-experiential approach. In this paper, evidence in support of EFT as a treatment approach will be reviewed along with research on two mechanisms of change, viewed as central to EFT, clients' emotional processing and the therapeutic relationship conditions. The implications for psychotherapy research are discussed. Given the methodological constraints, there is a need for more innovative methodologies and strategies to investigate specific psychotherapy processes within and across different approaches to map patterns and mechanisms of change to enhance theory, research, practice, and training.

  5. A European Perspective on Auditory Processing Disorder-Current Knowledge and Future Research Focus

    Directory of Open Access Journals (Sweden)

    Vasiliki (Vivian Iliadou

    2017-11-01

    Full Text Available Current notions of “hearing impairment,” as reflected in clinical audiological practice, do not acknowledge the needs of individuals who have normal hearing pure tone sensitivity but who experience auditory processing difficulties in everyday life that are indexed by reduced performance in other more sophisticated audiometric tests such as speech audiometry in noise or complex non-speech sound perception. This disorder, defined as “Auditory Processing Disorder” (APD or “Central Auditory Processing Disorder” is classified in the current tenth version of the International Classification of diseases as H93.25 and in the forthcoming beta eleventh version. APDs may have detrimental effects on the affected individual, with low esteem, anxiety, and depression, and symptoms may remain into adulthood. These disorders may interfere with learning per se and with communication, social, emotional, and academic-work aspects of life. The objective of the present paper is to define a baseline European APD consensus formulated by experienced clinicians and researchers in this specific field of human auditory science. A secondary aim is to identify issues that future research needs to address in order to further clarify the nature of APD and thus assist in optimum diagnosis and evidence-based management. This European consensus presents the main symptoms, conditions, and specific medical history elements that should lead to auditory processing evaluation. Consensus on definition of the disorder, optimum diagnostic pathway, and appropriate management are highlighted alongside a perspective on future research focus.

  6. Securing Canada’s Information-Technology Infrastructure: Context, Principles, and Focus Areas of Cybersecurity Research

    Directory of Open Access Journals (Sweden)

    Dan Craigen

    2013-07-01

    Full Text Available This article addresses the challenges of cybersecurity and ultimately the provision of a stable and resilient information-technology infrastructure for Canada and, more broadly, the world. We describe the context of current cybersecurity challenges by synthesizing key source material whose importance was informed by our own real-world experiences. Furthermore, we present a checklist of guiding principles to a unified response, complete with a set of action-oriented research topics that are linked to known operational limitations. The focus areas are used to drive the formulation of a unified and relevant research and experimental development program, thereby moving us towards a stable and resilient cyberinfrastructure. When cybersecurity is viewed as an inherently interdisciplinary problem of societal concern, we expect that fundamentally new research perspectives will emerge in direct response to domain-specific protection requirements for information-technology infrastructure. Purely technical responses to cybersecurity challenges will be inadequate because human factors are an inherent aspect of the problem. This article will interest managers and entrepreneurs. Senior management teams can assess new technical developments and product releases to fortify their current security solutions, while entrepreneurs can harness new opportunities to commercialize novel technology to solve a high-impact cybersecurity problem..

  7. Transferring diffractive optics from research to commercial applications: Part II - size estimations for selected markets

    Science.gov (United States)

    Brunner, Robert

    2014-04-01

    In a series of two contributions, decisive business-related aspects of the current process status to transfer research results on diffractive optical elements (DOEs) into commercial solutions are discussed. In part I, the focus was on the patent landscape. Here, in part II, market estimations concerning DOEs for selected applications are presented, comprising classical spectroscopic gratings, security features on banknotes, DOEs for high-end applications, e.g., for the semiconductor manufacturing market and diffractive intra-ocular lenses. The derived market sizes are referred to the optical elements, itself, rather than to the enabled instruments. The estimated market volumes are mainly addressed to scientifically and technologically oriented optical engineers to serve as a rough classification of the commercial dimensions of DOEs in the different market segments and do not claim to be exhaustive.

  8. Work-life balance of nursing faculty in research- and practice-focused doctoral programs.

    Science.gov (United States)

    Smeltzer, Suzanne C; Sharts-Hopko, Nancy C; Cantrell, Mary Ann; Heverly, Mary Ann; Jenkinson, Amanda; Nthenge, Serah

    2015-01-01

    The growing shortage of nursing faculty and the need for faculty to teach doctoral students to address the shortage call for examination of factors that may contribute to the shortage, including those that are potentially modifiable, including work-life balance.This descriptive study examined work-life balance of a national sample of nursing faculty teaching in research-focused and practice-focused doctoral programs. Data were collected through an online survey of 554 doctoral program faculty members to identify their perceptions of work-life balance and predictors of work-life balance. Work-life balance scores indicated better work-life balance than expected. Factors associated with good work-life balance included higher academic rank, having tenure, older age, years in education, current faculty position, and no involvement in clinical practice. Current faculty position was the best predictor of work-life balance. Although work-life balance was viewed positively by study participants, efforts are needed to strengthen factors related to positive work/life in view of the increasing workload of doctoral faculty as the numbers of doctoral students increase and the number of seasoned faculty decrease with anticipated waves of retirements. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Tanks Focus Area Alternative Salt Processing Research and Development Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Harmon, Harry D.

    2000-05-15

    In March 2000, DOE-Headquarters (HQ) requested the Tanks Focus Area (TFA)to assume management responsibility for the Salt Processing Project technology development program at Savannah River Site. The TFA was requested to conduct several activities, including review and revision of the technology development roadmaps, development of down-selection criteria, and preparation of a comprehensive Research and Development (R&D) Program Plan for three candidate cesium removal technologies, as well as the Alpha and strontium removal processes that must also be carried out. The three cesium removal candidate technologies are Crystalline Silicotitanate (CST) Non-Elutable Ion Exchange, Caustic Side Solvent Extraction (CSSX), and Small Tank Tetraphenylborate Precipitation (STTP). This plan describes the technology development needs for each process that must be satisfied in order to reach a down-selection decision, as well as continuing technology development required to support conceptual design activities.

  10. Tanks Focus Area Alternative Salt Processing Research and Development Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Harmon, Harry D.

    2000-11-30

    In March 2000, DOE-Headquarters (HQ) requested the Tanks Focus Area (TFA) to assume management responsibility for the Salt Processing Project technology development program at Savannah River Site. The TFA was requested to conduct several activities, including review and revision of the technology development roadmaps, development of down-selection criteria, and preparation of a comprehensive Research and Development (R&D) Program Plan for three candidate cesium removal technologies, as well as the Alpha and strontium removal processes that must also be carried out. The three cesium removal candidate technologies are Crystalline Silicotitanate (CST) Non-Elutable Ion Exchange, Caustic Side Solvent Extraction (CSSX), and Small Tank Tetraphenylborate Precipitation (STTP). This plan describes the technology development needs for each process that must be satisfied in order to reach a down-selection decision, as well as continuing technology development required to support conceptual design activities.

  11. EPR researches of tree cuts for estimating radio - ecological situation

    International Nuclear Information System (INIS)

    Bitenbayev, M.I.; Polyakov, A.I.

    2007-01-01

    Full text: The basic aim of present work is to study a possibility of nature object application, in this case the annual rings of trees, for reveal of the effects of post - radiation action for them by EPR method. The cuts of poplars at the age 70 years and older grown in various regions of Kazakhstan with increased level of radiation background were selected as the research objects. EPR spectra were registered for every annual ring separately at the room temperatures. On the basis of EPR experimental results it was ascertained that the EPR spectra of annual rings may be symbolically divided for two groups every of which is possessed of its own definite kind of the spectrum. The first group are the spectra of the annual rings relating to 1981 - 1999 years (in 1999 the trees were cut), and the second group are these of the rings relating 1934 - 1980 years. At that it has been showed that an additional exposure to γ-ray of Co 60 transforms the first group spectrum to the form typical for the second group, i.e. the radiation effect becomes apparent in these experiments. The analyses of EPR spectra parameters has been performed and a correlation between the dependences of intensity of certain components in the spectrum on gamma - irradiation dose and the age of the annul rings has been showed. One can suppose that the intensity changing of these spectrum components in the second group, concerned with free radical accumulation, was the results of long-term action to the object by ionizing radiations. The studied effects can be used for average estimation of absorbed doses of ionizing radiation by environment objects, in particular, by residents of regions surveyed

  12. Nuclear Waste Separation and Transmutation Research with Special Focus on Russian Transmutation Projects Sponsored by ISTC

    International Nuclear Information System (INIS)

    Conde, Henri; Blomgren, Jan; Olsson, Nils

    2003-03-01

    High-level nuclear reactor waste is made up of relatively few long-lived radioactive species, among them plutonium, that contribute to difficulties with its storage and disposal. Separation of these species from larger waste volumes mainly constituting of uranium (about 95 %) coupled with nuclear incineration to fission products of plutonium and the so called minor actinides (Neptunium, Americium, and Curium) and transmutation of some of the long lived fission products to short lived or stable isotopes represents a viable nuclear waste management strategy to drastically reduce the time and space requirements for a bed-rock repository of the remaining waste. A remarkable increase in the international research and development on partitioning and transmutation has occurred during the recent years. The road-map report published in April 2001 by The European Technical Working Group on ADS for the development of a European demonstration facility for nuclear waste transmutation has high-lighted the ongoing European research and pointed out the need for further research. The road-map has given the different research activities a position in the ultimate goal of producing an ADS demonstrator and is guiding research planning on the national as well as on the EU level. The Advanced Accelerator Application (3A) program in the US, with the long term goals to enhance long term public safety, provide benefits for the repository, reduce proliferation risks and improve prospects for nuclear power has focused the research on nuclear waste transmutation. The reports on the 3A program indicates a change of the US former abandonment position towards reprocessing and fast reactors due to a strong incentive to eliminate the reactor plutonium and to lower the amount of high level reactor waste for the Yucca Mountain repository. The SKB's proposed research and development program for the next 3 years (FUD01) was presented by SKB in September 2001. It is proposed that the research program

  13. A Study of Factors Related to Dissertation Progress among Doctoral Candidates: Focus on Students' Research Self-Efficacy as a Result of Their Research Training and Experiences.

    Science.gov (United States)

    Faghihi, Forooz; Rakow, Ernest A.; Ethington, Corinna

    This study examined relationships among doctoral candidates' background characteristics, research preparation, research environment, research involvement, student-advisor relationship, research self-efficacy, and dissertation progress. The study focused on differences in research self-efficacy and dissertation progress among students from the…

  14. [Advances in research on cognitive function related to temporal lobe epilepsy: focus on social cognitive function].

    Science.gov (United States)

    Yamano, Mitsuhiko; Akamatsu, Naoki; Tsuji, Sadatoshi

    2012-09-01

    Research on cognitive function related to temporal lobe epilepsy has thus far focused on memory, language, and general intelligence. Recently, however, the concept of social cognitive function has been proposed in the field of neuropsychology. Social cognitive function refers collectively to the higher cognitive functions that are essential in our social lives, and its representative aspects are facial expression recognition and decision-making. Emotional processing centered around the amygdala is thought to play a key role in the neural mechanism of this function. We conducted a study on the social cognitive function (decision-making) of patients with temporal lobe epilepsy, and found that this function is reduced in these patients, and that the right amygdalo-hippocampal complexes play an important role. In order to ensure the best possible treatment for epilepsy patients, it is necessary not only to make an accurate diagnosis and provide appropriate treatment, but also to provide support for enabling a smoother social life from the perspective of social cognitive function. Future research developments in this field are expected to contribute to total management in medical care for epilepsy patients.

  15. Innovation in Researching the Effects of Frame – Focused Instruction on Second Language Acquisition

    Directory of Open Access Journals (Sweden)

    Elena SOKOLOVA

    2010-01-01

    Full Text Available In the context of globalization the research of innovative teaching methods and techniques becomes relevant. The traditional teaching approach where the training of practice material is preceded by rule-presentation (explanation + mechanical formoriented practice doesn’t meet the requirements of constantly developing rational language processing. Contemporary studies are considering the ways how to allow second language learners to be rational in the sense that their mental models of language functioning are the most optimal. This paper outlines current cognitive perspectives on second language acquisition. Language learning involves the acquisition of frame instructions or input-processing instructions (explanation + structured-input activities. Competence and performance both emerge from the dynamic system of frequently used memorized constructions. Frames are dynamic contextualized activation of stereotyped situations. This system proves to be rational since it aims at optimal reflection of prior first language usage and induces learners to think consciously about some sort of rule in order to work out the meaning. The frame–based instruction consists of activities which present learners with a stimulus and require them to respond choosing the appropriate language form for communication. The targeted feature of such communicative tasks has two aims: 1. to stimulate communicative language use and 2. to target the use of a particular predetermined linguistic feature. The empirical research shows that frame-focused tasks direct learners attention to the meaning realized by the target form. Methodological basis includes some theoretical propositions from recent Relevance theory and cognitive linguistics.

  16. Advances in Proteomic Techniques for Cytokine Analysis: Focus on Melanoma Research

    Directory of Open Access Journals (Sweden)

    Helena Kupcova Skalnikova

    2017-12-01

    Full Text Available Melanoma is a skin cancer with permanently increasing incidence and resistance to therapies in advanced stages. Reports of spontaneous regression and tumour infiltration with T-lymphocytes makes melanoma candidate for immunotherapies. Cytokines are key factors regulating immune response and intercellular communication in tumour microenvironment. Cytokines may be used in therapy of melanoma to modulate immune response. Cytokines also possess diagnostic and prognostic potential and cytokine production may reflect effects of immunotherapies. The purpose of this review is to give an overview of recent advances in proteomic techniques for the detection and quantification of cytokines in melanoma research. Approaches covered span from mass spectrometry to immunoassays for single molecule detection (ELISA, western blot, multiplex assays (chemiluminescent, bead-based (Luminex and planar antibody arrays, ultrasensitive techniques (Singulex, Simoa, immuno-PCR, proximity ligation/extension assay, immunomagnetic reduction assay, to analyses of single cells producing cytokines (ELISpot, flow cytometry, mass cytometry and emerging techniques for single cell secretomics. Although this review is focused mainly on cancer and particularly melanoma, the discussed techniques are in general applicable to broad research field of biology and medicine, including stem cells, development, aging, immunology and intercellular communication.

  17. Detection and estimation research of high-speed railway catenary

    CERN Document Server

    Liu, Zhigang

    2017-01-01

    This book describes the wave characteristics of contact lines taking wind into consideration and discusses new methods for detecting catenary geometry, pantograph slide fault, and catenary support system faults. It also introduces wire-irregularity detection methods for catenary estimation, and discusses modern spectrum estimation tools for catenary. It is organized in three parts: the first discusses statistical characteristics of pantograph-catenary data, such as stationarity, periodicity, correlation, high-order statistical properties and wave characteristics of contact lines, which are the basis of pantograph-catenary relationship analysis. The second part includes geometry parameter detection and support-system fault detection in catenary, as well as slide-fault detection in pantographs, and presents some new detection algorithms and plans. The final part addresses catenary estimation, including detection of contact-line wire irregularities and estimation of catenary based on spectrum, and presents detec...

  18. Engaging families in physical activity research: a family-based focus group study.

    Science.gov (United States)

    Brown, Helen Elizabeth; Schiff, Annie; van Sluijs, Esther M F

    2015-11-25

    Family-based interventions present a much-needed opportunity to increase children's physical activity levels. However, little is known about how best to engage parents and their children in physical activity research. This study aimed to engage with the whole family to understand how best to recruit for, and retain participation in, physical activity research. Families (including a 'target' child aged between 8 and 11 years, their parents, siblings, and others) were recruited through schools and community groups. Focus groups were conducted using a semi-structured approach (informed by a pilot session). Families were asked to order cards listing the possible benefits of, and the barriers to, being involved in physical activity research and other health promotion activities, highlighting the items they consider most relevant, and suggesting additional items. Duplicate content analysis was used to identify transcript themes and develop a coding frame. Eighty-two participants from 17 families participated, including 17 'target' children (mean age 9.3 ± 1.1 years, 61.1% female), 32 other children and 33 adults (including parents, grandparents, and older siblings). Social, health and educational benefits were cited as being key incentives for involvement in physical activity research, with emphasis on children experiencing new things, developing character, and increasing social contact (particularly for shy children). Children's enjoyment was also given priority. The provision of child care or financial reward was not considered sufficiently appealing. Increased time commitment or scheduling difficulties were quoted as the most pertinent barriers to involvement (especially for families with several children), but parents commented these could be overcome if the potential value for children was clear. Lessons learned from this work may contribute to the development of effective recruitment and retention strategies for children and their families. Making the wide

  19. RESEARCH CAPACITIES OF UNIVERSITIES: ESTIMATION OF PARAMETERS AND MODELING OF THE DYNAMICS OF THE RESEARCH SYSTEMS

    Directory of Open Access Journals (Sweden)

    CAROLINA DELGADO HURTADO

    2017-12-01

    Full Text Available Research capacities are developed scientific skills that enable universities to accomplish the dissemination of high-quality scientific knowledge. Nowadays, the modeling of their dynamics is one of the most important concerns for the stakeholders related to the scientific activity, including university managers, private sector and government. In this context, the present article aims to approach the issue of modeling the capacities of the Universities’ research systems, presenting Systems Dynamics as an effective methodological tool for the treatment of data contained in intellectual capital indicators, allowing to estimate parameters, conditions and scenarios. The main contribution lays on the modeling and simulations accomplished for several scenarios, which display the critical variables and the more sensitive ones when building or strengthening research capacities. The establishment of parameters through regression techniques allowed to more accurately model the dynamics of the variables. This is an interesting contribution in terms of the accuracy of the simulations that later might be used to propose and carry out changes related to the management of the universities research. Future research with alternative modeling for social systems will allow to broaden the scope of the study.

  20. Focus group positioning and analysis: a commentary on adjuncts for enhancing the design of health care research.

    Science.gov (United States)

    Johnson, B C

    1990-01-01

    As health care competition increases, and as the penalties for making poor decisions become potentially more devastating, market research continues to play an increasingly important role in the decision-making process for hospitals. Concern over the appropriate use of market research and the costs related to it remains high. As such, efficiency in research design and clarity in research outcome are clearly the goals. This paper examines the focus group process and its adjunctive role in enhancing the overall design of health care market research. Specifically, the function and placement of focus groups within the research plan as well as several methods of creative focus group analysis are considered within the context of an effective research design.

  1. The Alsep Data Recovery Focus Group of NASA's Solar System Exploration Research Virtual Institute

    Science.gov (United States)

    Nagihara, S.; Lewis, L. R.; Nakamura, Y.; Williams, D. R.; Taylor, P. T.; Hills, H. K.; Kiefer, W. S.; Neal, C. R.; Schmidt, G. K.

    2014-12-01

    Astronauts on Apollo 12, 14, 15, 16, and 17 deployed instruments on the Moon for 14 geophysical experiments (passive & active seismic, heat flow, magnetics, etc.) from 1969 to 1972. These instruments were called Apollo Lunar Surface Experiments Packages (ALSEPs). ALSEPs kept transmitting data to the Earth until September 1977. When the observation program ended in 1977, a large portion of these data were not delivered to the National Space Science Data Center for permanent archive. In 2010, for the purpose of searching, recovering, preserving, and analyzing the data that were not previously archived, NASA's then Lunar Science Institute formed the ALSEP Data Recovery Focus Group. The group consists of current lunar researchers and those involved in the ALSEP design and data analysis in the 1960s and 1970s. Among the data not previously archived were the 5000+ 7-track open-reel tapes that recorded raw data from all the ALSEP instruments from April 1973 to February 1976 ('ARCSAV tapes'). These tapes went missing in the decades after Apollo. One of the major achievements of the group so far is that we have found 450 ARCSAV tapes from April to June 1975 and that we are extracting data from them. There are 3 other major achievements by the group. First, we have established a web portal at the Lunar and Planetary Institute, where ~700 ALSEP-related documents, totaling ~40,000 pages, have been digitally scanned and cataloged. Researchers can search and download these documents at www.lpi.usra.edu/ lunar/ALSEP/. Second, we have been retrieving notes and reports left behind by the now deceased/retired ALSEP investigators at their home institutions. Third, we have been re-analyzing the ALSEP data using the information from the recently recovered metadata (instrument calibration data, operation logs, etc.). Efforts are ongoing to get these data permanently archived in the Planetary Data System (PDS).

  2. How to estimate the health benefits of additional research and changing clinical practice

    OpenAIRE

    Claxton, Karl; Griffin, Susan; Koffijberg, Hendrik; McKenna, Claire

    2015-01-01

    A simple extension of standard meta-analysis can provide quantitative estimates of the potential health benefits of further research and of implementing the findings of existing research, which can help inform research prioritisation and efforts to change clinical practice

  3. How to estimate the health benefits of additional research and changing clinical practice

    OpenAIRE

    Claxton, Karl; Griffin, Susan; Koffijberg, Hendrik; McKenna, Claire

    2015-01-01

    A simple extension of standard metaanalysis can provide quantitative estimates of the potential health benefits of further research and of implementing the findings of existing research, which can help inform research prioritisation and efforts to change clinical practice

  4. Focus on the research utility of intravascular ultrasound - comparison with other invasive modalities

    Directory of Open Access Journals (Sweden)

    Hoye Angela

    2011-01-01

    Full Text Available Abstract Intravascular ultrasound (IVUS is an invasive modality which provides cross-sectional images of a coronary artery. In these images both the lumen and outer vessel wall can be identified and accurate estimations of their dimensions and of the plaque burden can be obtained. In addition, further processing of the IVUS backscatter signal helps in the characterization of the type of the plaque and thus it has been used to study the natural history of the atherosclerotic evolution. On the other hand its indigenous limitations do not allow IVUS to assess accurately stent struts coverage, existence of thrombus or exact site of plaque rupture and to identify some of the features associated with increased plaque vulnerability. In order this information to be obtained, other modalities such as optical coherence tomography, angioscopy, near infrared spectroscopy and intravascular magnetic resonance imaging have either been utilized or are under evaluation. The aim of this review article is to present the current utilities of IVUS in research and to discuss its advantages and disadvantages over the other imaging techniques.

  5. Participatory design in Parkinson's research with focus on the symptomatic domains to be measured.

    Science.gov (United States)

    Serrano, J Artur; Larsen, Frank; Isaacs, Tom; Matthews, Helen; Duffen, Joy; Riggare, Sara; Capitanio, Fulvio; Ferreira, Joaquim J; Domingos, Josefa; Maetzler, Walter; Graessner, Holm

    2015-01-01

    There is a growing interest in the objective assessment of health related outcomes using technology providing quality measurements to be applied not only in daily clinical practice, but also in scientific research. Differences in the understandings of the condition and the terminology used between people with Parkinson's (PwPs), clinicians and technical developers may influence the progress of a participatory design process. This paper reports on a participatory design process to achieve a consensus among PwPs, clinicians and technologists over the selection of a set of symptomatic domains to be continuously assessed, in order to provide results relevant to both PwPs and clinicians. The methods used were a Web based user survey, end-user focus groups, ranking by combined methods, a Delphi process performed among clinicians and scientists, and prioritization of the results in a concertation workshop for PwPs, clinicians and technologists. The following symptomatic domains were commonly agreed by PwPs and clinicians to be of central importance in a system of continuous assessment: hypokinesia/bradykinesia, tremor, sway, gait, sleep and cognition. This list satisfied both the needs of the PwPs and the concerns of the clinicians regarding the means of advancing new strategies in assessment and interventions in PD. A participatory design strategy allowed the definition of a consensual list of symptomatic domains. Both the strategy and the achieved results may be of relevance for similar interdisciplinary approaches in the field of PD using a participatory design involving patients, clinicians and technologists.

  6. Development of X-ray and ion diagnostic methods for plasma focus research

    International Nuclear Information System (INIS)

    Sadowski, M.

    1986-12-01

    A review of experimental methods used for investigation of X-rays and ion-beams emmited from plasma focus facilities is presented. The research program has been realized at the Institute for Nuclear Studies in Swierk and at the Institut fuer Plasmaforschung in Stuttgart, within the frames of an international co-operation. The studies on ion emission from different PF facilities are reviewed. The application of CN-films with Al-filters and of different ion-pinhole cameras is described. The use of a Thomson mass-spectrometer adopted for plasma studies is presented. The time-resolved measurements combined with a simultaneous mass- and energy-analysis of the ion beams are also described. The most important results of these studies are summarized. Particular attention is also paid to the studies of the X-ray emission. The use of stereoscopic sets of vacuum pinhole cameras with thin Be-filters is described. The application of X-ray pinhole cameras equipped with miniature scintillators for time-resolved measurements is also presented. The most important results of the X-ray emission studies are summarized. 35 refs., 12 figs. (author)

  7. Lunar e-Library: A Research Tool Focused on the Lunar Environment

    Science.gov (United States)

    McMahan, Tracy A.; Shea, Charlotte A.; Finckenor, Miria; Ferguson, Dale

    2007-01-01

    As NASA plans and implements the Vision for Space Exploration, managers, engineers, and scientists need lunar environment information that is readily available and easily accessed. For this effort, lunar environment data was compiled from a variety of missions from Apollo to more recent remote sensing missions, such as Clementine. This valuable information comes not only in the form of measurements and images but also from the observations of astronauts who have visited the Moon and people who have designed spacecraft for lunar missions. To provide a research tool that makes the voluminous lunar data more accessible, the Space Environments and Effects (SEE) Program, managed at NASA's Marshall Space Flight Center (MSFC) in Huntsville, AL, organized the data into a DVD knowledgebase: the Lunar e-Library. This searchable collection of 1100 electronic (.PDF) documents and abstracts makes it easy to find critical technical data and lessons learned from past lunar missions and exploration studies. The SEE Program began distributing the Lunar e-Library DVD in 2006. This paper describes the Lunar e-Library development process (including a description of the databases and resources used to acquire the documents) and the contents of the DVD product, demonstrates its usefulness with focused searches, and provides information on how to obtain this free resource.

  8. Traditional, complementary, and alternative medicine: Focusing on research into traditional Tibetan medicine in China.

    Science.gov (United States)

    Song, Peipei; Xia, Jufeng; Rezeng, Caidan; Tong, Li; Tang, Wei

    2016-07-19

    As a form of traditional, complementary, and alternative medicine (TCAM), traditional Tibetan medicine has developed into a mainstay of medical care in Tibet and has spread from there to China and then to the rest of the world. Thus far, research on traditional Tibetan medicine has focused on the study of the plant and animal sources of traditional medicines, study of the histology of those plants and animals, chemical analysis of traditional medicines, pharmacological study of those medicines, and evaluation of the clinical efficacy of those medicines. A number of papers on traditional Tibetan medicines have been published, providing some evidence of the efficacy of traditional Tibetan medicine. However, many traditional Tibetan medicines have unknown active ingredients, hampering the establishment of drug quality standards, the development of new medicines, commercial production of medicines, and market availability of those medicines. Traditional Tibetan medicine must take several steps to modernize and spread to the rest of the world: the pharmacodynamics of traditional Tibetan medicines need to be determined, the clinical efficacy of those medicines needs to be verified, criteria to evaluate the efficacy of those medicines need to be established in order to guide their clinical use, and efficacious medicines need to be acknowledged by the pharmaceutical market. The components of traditional Tibetan medicine should be studied, traditional Tibetan medicines should be screened for their active ingredients, and techniques should be devised to prepare and manufacture those medicines.

  9. Utilizing Dietary Micronutrient Ratios in Nutritional Research May be More Informative than Focusing on Single Nutrients

    Directory of Open Access Journals (Sweden)

    Owen J. Kelly

    2018-01-01

    Full Text Available The 2015 US dietary guidelines advise the importance of good dietary patterns for health, which includes all nutrients. Micronutrients are rarely, if ever, consumed separately, they are not tissue specific in their actions and at the molecular level they are multitaskers. Metabolism functions within a seemingly random cellular milieu however ratios are important, for example, the ratio of adenosine triphosphate to adenosine monophosphate, or oxidized to reduced glutathione. Health status is determined by simple ratios, such as the waist hip ratio, or ratio of fat mass to lean mass. Some nutrient ratios exist and remain controversial such as the omega-6/omega-3 fatty acid ratio and the sodium/potassium ratio. Therefore, examining ratios of micronutrients may convey more information about how diet and health outcomes are related. Summarized micronutrient intake data, from food only, from the National Health and Nutrition Examination Survey, were used to generate initial ratios. Overall, in this preliminary analysis dietary ratios of micronutrients showed some differences between intakes and recommendations. Principles outlined here could be used in nutritional epidemiology and in basic nutritional research, rather than focusing on individual nutrient intakes. This paper presents the concept of micronutrient ratios to encourage change in the way nutrients are regarded.

  10. Building a science of partnership-focused research: forging and sustaining partnerships to support child mental health prevention and services research.

    Science.gov (United States)

    Bradshaw, Catherine P; Haynes, Katherine Taylor

    2012-07-01

    Building on growing interest in translational research, this paper provides an overview of a special issue of Administration and Policy in Mental Health and Mental Health Service Research, which is focused on the process of forging and sustaining partnerships to support child mental health prevention and services research. We propose that partnership-focused research is a subdiscipline of translational research which requires additional research to better refine the theoretical framework and the core principles that will guide future research and training efforts. We summarize some of the major themes across the eight original articles and three commentaries included in the special issue. By advancing the science of partnership-focused research we will be able to bridge the gap between child mental health prevention and services research and practice.

  11. Cost Estimation for Cross-organizational ERP Projects: Research Perspectives

    NARCIS (Netherlands)

    Daneva, Maia; Bieman, J.; Wieringa, Roelf J.

    There are many methods for estimating size, effort, schedule and other cost aspects of IS projects, but only one specifically developed for Enterprise Resource Planning (ERP) [67] and none for simultaneous, interdependent ERP projects in a cross-organizational context. The objective of this paper is

  12. Family Literacy and Second Language Literacy Research: Focus on Language Minority Children

    Directory of Open Access Journals (Sweden)

    Özgür Yıldırım

    2013-04-01

    Full Text Available Problem Statement: Countries like the U. S. A. or Canada have citizens from various ethnic backgrounds. Although English is the dominant language in many parts of these countries, immigrants generally prefer speaking their native language when they are in their homes. Whatever the reason for using native language at home is, when we consider the children in these families, we can say that being exposed to different languages at home and at school may be a problem for their language development.Purpose of Study: There are many studies conducted in order to better understand the problems of language minority children. A great deal of literature on language minority students focuses on the ties between these children‟s literacy development and their literacy practices at home. In other words, these studies aim to see how the literacy events these children are exposed to at home affect their literacy learning in the second language.Methods: This paper is an attempt to put together and discuss various theoretical and empirical studies conducted on the literacy development of language minority children in English speaking countries.Findings: Literacy education of language minority students is not an easy task. It is very complicated and difficult to achieve as it requires a complete collaboration among all the responsible parties (teachers, families, researchers, education policy makers, school administrators. Conclusion and Recommendations: Successful collaboration among all the involved parties would bring successful outcomes in terms of children‟s healthy literacy development. The collaboration between teachers and families is the most vital one because these two parties are the ones that have one-to-one interaction with children.

  13. Cost estimation of hydrogen and DME produced by nuclear heat utilization system. Joint research

    International Nuclear Information System (INIS)

    Shiina, Yasuaki; Nishihara, Tetsuo

    2003-09-01

    Research of hydrogen energy has been performed in order to spread use of the hydrogen energy in 2020 or 2030. It will take, however, many years for the hydrogen energy to be used very easily like gasoline, diesel oil and city gas in all of countries. During the periods, low CO 2 release liquid fuels would be used together with hydrogen. Recently, di-methyl-either (DME) has been noticed as one of the substitute liquid fuels of petroleum. Such liquid fuels can be produced from the mixed gas such as hydrogen and carbon oxide which are produced by steam reforming hydrogen generation system by the use of nuclear heat. Therefore, the system would be one of the candidates of future system of nuclear heat utilization. In the present study, we focused on the production of hydrogen and DME. Economic evaluation was estimated for hydrogen and DME production in commercial and nuclear heat utilization plant. At first, heat and mass balance of each process in commercial plant of hydrogen production was estimated and commercial prices of each process were derived. Then, price was estimated when nuclear heat was used instead of required heat of commercial plant. Results showed that the production prices produced by nuclear heat were cheaper by 10% for hydrogen and 3% for DME. With the consideration of reduction effect of CO 2 release, utilization of nuclear heat would be more effective. (author)

  14. Focus Groups in Qualitative Research: Culturally Sensitive Methodology for the Arabian Gulf?

    Science.gov (United States)

    Thomas, Andrew

    2008-01-01

    This article explores whether focus groups can constitute a culturally sensitive method of data gathering for educational leadership, management and related areas in a Gulf-Arab cultural context. Reviewing the literature on focus groups and cross-cultural psychology for the Arab region, it identifies key notions related to societal values such as…

  15. The need for mental health services research focusing on poor young women.

    Science.gov (United States)

    Miranda, Jeanne; Green, Bonnie L.

    1999-06-01

    to be learned about the mental health status and needs of poor women, along with the impact of loss of public support on their physical and mental health. Access to mental health care within a managed care setting also needs to be addressed, and care taken to understand the particular needs of poor populations that will actually make these services accessible to them. Insufficient attention has thus far been paid to the cost implications of providing these services to the poor. While providing treatment is associated with significant costs, the costs of not providing care, especially the effects of depression on offspring, should not be overlooked. CHALLENGES TO EXAMINING MENTAL HEALTH IN POOR WOMEN: A number of suggestions were made for addressing practical and methodological challenges to providing mental health services. These include placing services for these individuals within their familiar medical settings, which requires close working relationships between psychiatric and medical personnel within these settings. Outreach is a necessary part of getting poor women into treatment, and should be a routine part of helping women become engaged with caregivers. Providing culturally sensitive treatments is an important focus too, through developing knowledge about the culturally based customs and expectations of target groups. Measurement issues need to be attended to, as most research instruments have been developed on middle class populations, and have not been examined for their psychometric properties and norms in less advantaged groups. Careful translation techniques are also required. Finally, working with institutions sponsoring research to educate them about special problems and challenges with these groups will help improve the quality and efficiency of the work accomplished.

  16. Focus on CSIR research in water resources: CSIR’S environmental human health risk assessment

    CSIR Research Space (South Africa)

    Genthe, Bettina

    2007-08-01

    Full Text Available Environmental health risk assessment deals with risks associated with manmade and natural environmental hazards. Environmental health risk assessment provides a means of estimating the probability of adverse health effects associated with hazards...

  17. Focus on sex differences in grant applications submitted to the Netherlands Organization for Health Research and Development

    NARCIS (Netherlands)

    Keuken, Debby G.; Haafkens, Joke A.; Klazinga, Niek S.

    2007-01-01

    ABSTRACT: BACKGROUND: Several measures have been implemented at international level to ensure that there is a greater focus on sex differences in health research. This study evaluates the effect of various formal incentives that were introduced by a Dutch financer of health research to encourage

  18. Case Study Observational Research: A Framework for Conducting Case Study Research Where Observation Data Are the Focus.

    Science.gov (United States)

    Morgan, Sonya J; Pullon, Susan R H; Macdonald, Lindsay M; McKinlay, Eileen M; Gray, Ben V

    2017-06-01

    Case study research is a comprehensive method that incorporates multiple sources of data to provide detailed accounts of complex research phenomena in real-life contexts. However, current models of case study research do not particularly distinguish the unique contribution observation data can make. Observation methods have the potential to reach beyond other methods that rely largely or solely on self-report. This article describes the distinctive characteristics of case study observational research, a modified form of Yin's 2014 model of case study research the authors used in a study exploring interprofessional collaboration in primary care. In this approach, observation data are positioned as the central component of the research design. Case study observational research offers a promising approach for researchers in a wide range of health care settings seeking more complete understandings of complex topics, where contextual influences are of primary concern. Future research is needed to refine and evaluate the approach.

  19. Health effects research and regulation of diesel exhaust: an historical overview focused on lung cancer risk.

    Science.gov (United States)

    Hesterberg, Thomas W; Long, Christopher M; Bunn, William B; Lapin, Charles A; McClellan, Roger O; Valberg, Peter A

    2012-06-01

    The mutagenicity of organic solvent extracts from diesel exhaust particulate (DEP), first noted more than 55 years ago, initiated an avalanche of diesel exhaust (DE) health effects research that now totals more than 6000 published studies. Despite an extensive body of results, scientific debate continues regarding the nature of the lung cancer risk posed by inhalation of occupational and environmental DE, with much of the debate focused on DEP. Decades of scientific scrutiny and increasingly stringent regulation have resulted in major advances in diesel engine technologies. The changed particulate matter (PM) emissions in "New Technology Diesel Exhaust (NTDE)" from today's modern low-emission, advanced-technology on-road heavy-duty diesel engines now resemble the PM emissions in contemporary gasoline engine exhaust (GEE) and compressed natural gas engine exhaust more than those in the "traditional diesel exhaust" (TDE) characteristic of older diesel engines. Even with the continued publication of epidemiologic analyses of TDE-exposed populations, this database remains characterized by findings of small increased lung cancer risks and inconsistent evidence of exposure-response trends, both within occupational cohorts and across occupational groups considered to have markedly different exposures (e.g. truckers versus railroad shopworkers versus underground miners). The recently published National Institute for Occupational Safety and Health (NIOSH)-National Cancer Institute (NCI) epidemiologic studies of miners provide some of the strongest findings to date regarding a DE-lung cancer association, but some inconsistent exposure-response findings and possible effects of bias and exposure misclassification raise questions regarding their interpretation. Laboratory animal studies are negative for lung tumors in all species, except for rats under lifetime TDE-exposure conditions with durations and concentrations that lead to "lung overload." The species specificity of the

  20. Health effects research and regulation of diesel exhaust: an historical overview focused on lung cancer risk

    Science.gov (United States)

    Hesterberg, Thomas W.; Long, Christopher M.; Bunn, William B.; Lapin, Charles A.; McClellan, Roger O.; Valberg, Peter A.

    2012-01-01

    The mutagenicity of organic solvent extracts from diesel exhaust particulate (DEP), first noted more than 55 years ago, initiated an avalanche of diesel exhaust (DE) health effects research that now totals more than 6000 published studies. Despite an extensive body of results, scientific debate continues regarding the nature of the lung cancer risk posed by inhalation of occupational and environmental DE, with much of the debate focused on DEP. Decades of scientific scrutiny and increasingly stringent regulation have resulted in major advances in diesel engine technologies. The changed particulate matter (PM) emissions in “New Technology Diesel Exhaust (NTDE)” from today's modern low-emission, advanced-technology on-road heavy-duty diesel engines now resemble the PM emissions in contemporary gasoline engine exhaust (GEE) and compressed natural gas engine exhaust more than those in the “traditional diesel exhaust” (TDE) characteristic of older diesel engines. Even with the continued publication of epidemiologic analyses of TDE-exposed populations, this database remains characterized by findings of small increased lung cancer risks and inconsistent evidence of exposure-response trends, both within occupational cohorts and across occupational groups considered to have markedly different exposures (e.g. truckers versus railroad shopworkers versus underground miners). The recently published National Institute for Occupational Safety and Health (NIOSH)-National Cancer Institute (NCI) epidemiologic studies of miners provide some of the strongest findings to date regarding a DE-lung cancer association, but some inconsistent exposure-response findings and possible effects of bias and exposure misclassification raise questions regarding their interpretation. Laboratory animal studies are negative for lung tumors in all species, except for rats under lifetime TDE-exposure conditions with durations and concentrations that lead to'lung overload."The species specificity

  1. Still Human: A Call for Increased Focus on Ethical Standards in Cadaver Research.

    Science.gov (United States)

    Bach, Michelle C

    2016-12-01

    Research on human cadavers is an important mechanism of scientific progress and comprises a large industry in the United States. However, despite its importance and influence, there is little ethical or regulatory oversight of cadaver-based research. This lack of transparency raises important ethical questions. Thus, this paper serves as a call for ethicists and regulators to pay increased attention to cadaver research. I argue that cadaver research ought to be considered a subset of human subjects research and held accountable to higher ethical standards. After describing current practices, I argue that oversight of cadaver research as a form of human subjects research is appropriate because cadaver research is similar to other types of human research, participants in cadaver research incur risks of harm, and a current lack of oversight has allowed the cadaver industry to entice research participation through ethically questionable practices. This paper urges greater dialogue among human subjects research ethicists and regulators about what constitutes appropriate protections for participants in cadaver research.

  2. [Priorities for health policy and systems research focused on human resources in health].

    Science.gov (United States)

    Reveiz, Ludovic; Chapman, Evelina; Flórez, Carlos E Pinzón; Torres, Rubén

    2013-11-01

    Identify priorities for health policy and systems research related to human resources in Latin America and Caribbean countries. An online survey was designed based on a search in PubMed, Cochrane Library, and LILACS that contributed previously prioritized research questions. Respondents, mainly researchers and decision-makers, were identified through various sources. The first round, directed at researchers, aimed at refining and adding research questions and prioritizing questions that researchers regarded as relevant or very relevant. The second round was directed at researchers and decision-makers. A question was considered a priority when 50% (or more) of respondents described it as "relevant" or "very relevant." The first round included 20 questions on human resources and 33/66 researchers responded. Questions suggested by the researchers were added, resulting in 26 questions for the second round, which were sent to 121 researchers and decision-makers. Respondent representation by country was uniform in both rounds. In the second round, 14/26 (54%) questions were described as very relevant. Priority issues related to regulation of the market, integration of education and health care needs, and distribution of human resources. The response rate was 50% in the first round (33/66), and 34% in the second round (41/121). The results of this exercise provide a starting point for mobilization of resources for health policy and systems research. Identification of health systems research priorities is an effective and efficient strategy for reorienting political, financial, management, and social organization efforts for attaining universal health coverage.

  3. Using prediction markets to estimate the reproducibility of scientific research

    Science.gov (United States)

    Dreber, Anna; Pfeiffer, Thomas; Almenberg, Johan; Isaksson, Siri; Wilson, Brad; Chen, Yiling; Nosek, Brian A.; Johannesson, Magnus

    2015-01-01

    Concerns about a lack of reproducibility of statistically significant results have recently been raised in many fields, and it has been argued that this lack comes at substantial economic costs. We here report the results from prediction markets set up to quantify the reproducibility of 44 studies published in prominent psychology journals and replicated in the Reproducibility Project: Psychology. The prediction markets predict the outcomes of the replications well and outperform a survey of market participants’ individual forecasts. This shows that prediction markets are a promising tool for assessing the reproducibility of published scientific results. The prediction markets also allow us to estimate probabilities for the hypotheses being true at different testing stages, which provides valuable information regarding the temporal dynamics of scientific discovery. We find that the hypotheses being tested in psychology typically have low prior probabilities of being true (median, 9%) and that a “statistically significant” finding needs to be confirmed in a well-powered replication to have a high probability of being true. We argue that prediction markets could be used to obtain speedy information about reproducibility at low cost and could potentially even be used to determine which studies to replicate to optimally allocate limited resources into replications. PMID:26553988

  4. Research on parafoil stability using a rapid estimate model

    Directory of Open Access Journals (Sweden)

    Hua YANG

    2017-10-01

    Full Text Available With the consideration of rotation between canopy and payload of parafoil system, a four-degree-of-freedom (4-DOF longitudinal static model was used to solve parafoil state variables in straight steady flight. The aerodynamic solution of parafoil system was a combination of vortex lattice method (VLM and engineering estimation method. Based on small disturbance assumption, a 6-DOF linear model that considers canopy additional mass was established with benchmark state calculated by 4-DOF static model. Modal analysis of a dynamic model was used to calculate the stability parameters. This method, which is based on a small disturbance linear model and modal analysis, is high-efficiency to the study of parafoil stability. It is well suited for rapid stability analysis in the preliminary stage of parafoil design. Using this method, this paper shows that longitudinal and lateral stability will both decrease when a steady climbing angle increases. This explains the wavy track of the parafoil observed during climbing.

  5. Using prediction markets to estimate the reproducibility of scientific research.

    Science.gov (United States)

    Dreber, Anna; Pfeiffer, Thomas; Almenberg, Johan; Isaksson, Siri; Wilson, Brad; Chen, Yiling; Nosek, Brian A; Johannesson, Magnus

    2015-12-15

    Concerns about a lack of reproducibility of statistically significant results have recently been raised in many fields, and it has been argued that this lack comes at substantial economic costs. We here report the results from prediction markets set up to quantify the reproducibility of 44 studies published in prominent psychology journals and replicated in the Reproducibility Project: Psychology. The prediction markets predict the outcomes of the replications well and outperform a survey of market participants' individual forecasts. This shows that prediction markets are a promising tool for assessing the reproducibility of published scientific results. The prediction markets also allow us to estimate probabilities for the hypotheses being true at different testing stages, which provides valuable information regarding the temporal dynamics of scientific discovery. We find that the hypotheses being tested in psychology typically have low prior probabilities of being true (median, 9%) and that a "statistically significant" finding needs to be confirmed in a well-powered replication to have a high probability of being true. We argue that prediction markets could be used to obtain speedy information about reproducibility at low cost and could potentially even be used to determine which studies to replicate to optimally allocate limited resources into replications.

  6. Research highlights from the 2017 ERS International Congress: airway diseases in focus

    Directory of Open Access Journals (Sweden)

    Cecilia Andersson

    2018-03-01

    Full Text Available For another year, high-quality research studies from around the world transformed the annual ERS International Congress into a vivid platform to discuss trending research topics, to produce new research questions and to further push the boundaries of respiratory medicine and science. This article reviews only some of the high-quality research studies on asthma, chronic obstructive pulmonary disease (COPD, bronchiectasis and chronic cough that were presented during the congress through the Airway Diseases Assembly (ERS Assembly 5 and places them into the context of current knowledge and research challenges.

  7. Research as an event: a novel approach to promote patient-focused drug development

    Directory of Open Access Journals (Sweden)

    Tsai JH

    2018-05-01

    Full Text Available Jui-Hua Tsai, Ellen Janssen, John FP Bridges Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA Abstract: Patient groups are increasingly engaging in research to understand patients’ preferences and incorporate their perspectives into drug development and regulation. Several models of patient engagement have emerged, but there is little guidance on how to partner with patient groups to engage the disease community. Our group has been using an approach to engage patient groups that we call research as an event. Research as an event is a method for researchers to use a community-centered event to engage patients in their own environment at modest incremental cost. It is a pragmatic solution to address the challenges of engaging patients in research to minimize patients’ frustration, decrease the time burden, and limit the overall cost. The community, the event, and the research are the three components that constitute the research as an event framework. The community represents a disease-specific community. The event is a meeting of common interest for patients and other stakeholders, such as a patient advocacy conference. The research describes activities in engaging the community for the purpose of research. Research as an event follows a six-step approach. A case study is used to demonstrate the six steps followed by recommendations for future implementation. Keywords: patients’ perspectives, decision making, drug approval, patient engagement, patient organization, patients’ preference

  8. Mrg: A Magnitude Scale for 1 s Rayleigh Waves at Local Distances with Focus on Yield Estimation

    Science.gov (United States)

    2016-08-23

    definition for filtering Rg near 1 s period at distances between 2-100 km. We used the new formula to estimate MRg for 39 small (37 ≤ Y ≤ 12,270 kg TNT...the Butterworth filter order (Russell, 2006). Filter Definition . To estimate the time-domain amplitude of Rg, we filter the time series with a 2nd... phenomenology experiments, including the Arizona Source Phenomenology Experiment (AZ-SPE), Bighorn Active Seismic Experiment (BASE), the HUMMING ALBATROS

  9. Focus Group Research on the Implications of Adopting the Unified English Braille Code

    Science.gov (United States)

    Wetzel, Robin; Knowlton, Marie

    2006-01-01

    Five focus groups explored concerns about adopting the Unified English Braille Code. The consensus was that while the proposed changes to the literary braille code would be minor, those to the mathematics braille code would be much more extensive. The participants emphasized that "any code that reduces the number of individuals who can access…

  10. Guidance on Performing Focused Ethnographies with an Emphasis on Healthcare Research

    Science.gov (United States)

    Higginbottom, Gina M. A.; Pillay, Jennifer J.; Boadu, Nana Y.

    2013-01-01

    Focused ethnographies can have meaningful and useful application in primary care, community, or hospital healthcare practice, and are often used to determine ways to improve care and care processes. They can be pragmatic and efficient ways to capture data on a specific topic of importance to individual clinicians or clinical specialties. While…

  11. Challenges to socio-economic research in a changing society - with a special focus on Greenland

    DEFF Research Database (Denmark)

    Poppel, Birger; Rasmussen, Rasmus Ole; Winther, Gorm

    2005-01-01

    The process of changes in Arctic societies has been from a cultural order to an economic order, and from a closed society based on barter and subsistence to a society based on economic exchange through monetary means. Consequently, understanding the currents of change requires a definite focus...

  12. A New Method for Research on the Center-Focus Problem of Differential Systems

    OpenAIRE

    Zhou, Zhengxin

    2014-01-01

    We will introduce Mironenko’s method to discuss the Poincaré center-focus problem, and compare the methods of Lyapunov and Mironenko. We apply the Mironenko method to discuss the qualitative behavior of solutions of some planar polynomial differential systems and derive the sufficient conditions for a critical point to be a center.

  13. Focus on Basics: Connecting Research and Practice: Workplace Education, Volume 7, Issue B

    Science.gov (United States)

    National Center for the Study of Adult Learning and Literacy, 2004

    2004-01-01

    This issue focuses on workplace education and includes the following articles: "After the Grant Is Over" (Connie Nelson); "Around to Stay" (Shirley Penn and Mary Zorn); "A Conversation with FOB: What Benefits Does Workplace Ed Offer the Provider?"; "Reading Work" (Tracy Defoe and Sue Folinsbee); "Much More than ABE" (Don Block and Lori…

  14. COURSE : a new industry led consortium to focus and accelerate energy resources research at Alberta University

    Energy Technology Data Exchange (ETDEWEB)

    Rodgers, R.J. [Imperial Oil Resources Ltd., Calgary, AB (Canada); Bailey, R. [Alberta Oil Sands Technology and Research Authority, Edmonton, AB (Canada); Kirk, M. [Calgary Univ., AB (Canada); Luhning, R.W. [Petroleum Recovery Inst., Calgary, AB (Canada); Kratochvil, R. [Alberta Univ., Edmonton, AB (Canada)

    2000-06-01

    This paper described a new initiative entitled COURSE (Coordination of University Research for Synergy and Effectiveness) which has been created through the collaboration of the energy industry, universities and the Alberta government to promote research in the field of energy resources. Calls for research proposals went out in June 1999 and January 2000. The selected projects will be funded by the Alberta Ministry of Innovation and Science through the Alberta Oil Sands Technology and Research Authority (AOSTRA). The major objectives of COURSE are to increase and align fundamental breakthrough university research with the industry needs, and to provide results that exceed what would be achieved by one university alone. An agreement has been reached whereby the universities own the technology and are the exclusive license agents of the research.

  15. Perspectives on Research Participation and Facilitation Among Dialysis Patients, Clinic Personnel, and Medical Providers: A Focus Group Study.

    Science.gov (United States)

    Flythe, Jennifer E; Narendra, Julia H; Dorough, Adeline; Oberlander, Jonathan; Ordish, Antoinette; Wilkie, Caroline; Dember, Laura M

    2017-12-19

    Most prospective studies involving individuals receiving maintenance dialysis have been small, and many have had poor clinical translatability. Research relevance can be enhanced through stakeholder engagement. However, little is known about dialysis clinic stakeholders' perceptions of research participation and facilitation. The objective of this study was to characterize the perspectives of dialysis clinic stakeholders (patients, clinic personnel, and medical providers) on: (1) research participation by patients and (2) research facilitation by clinic personnel and medical providers. We also sought to elucidate stakeholder preferences for research communication. Qualitative study. 7 focus groups (59 participants: 8 clinic managers, 14 nurses/patient care technicians, 8 social workers/dietitians, 11 nephrologists/advanced practice providers, and 18 patients/care partners) from 7 North Carolina dialysis clinics. Clinics and participants were purposively sampled. Focus groups were recorded and transcribed. Thematic analysis. We identified 11 themes that captured barriers to and facilitators of research participation by patients and research facilitation by clinic personnel and medical providers. We collapsed these themes into 4 categories to create an organizational framework for considering stakeholder (narrow research understanding, competing personal priorities, and low patient literacy and education levels), relationship (trust, buy-in, and altruistic motivations), research design (convenience, follow-up, and patient incentives), and dialysis clinic (professional demands, teamwork, and communication) aspects that may affect stakeholder interest in participating in or facilitating research. These themes appear to shape the degree of research readiness of a dialysis clinic environment. Participants preferred short research communications delivered in multiple formats. Potential selection bias and inclusion of English-speaking participants only. Our findings

  16. Overview on neutron beam industry-focused strategic research in Malaysia

    International Nuclear Information System (INIS)

    Abdul Aziz Mohamed; Razali Kassim; Abdul Jalil Abdul Hamid; Azali Muhammad; Muhammad Rawi Mohd Zain; Azhar Azmi

    2002-01-01

    The TRIGA MARK II research reactor (RTP) at the Malaysian Institute for Nuclear Technology Research (MINT) was commissioned in July 1982. RTP is a 1 MW steady state reactor which being used for reactor training and research related to neutron. Since then various works have been performed to utilise the neutrons produced from this steady state reactor. Projects undertaken are the development and utilization of the neutron radiography (myNR) and small angle neutron scattering (mySANS) facilities. This poster highlights the recent status the above neutron beam facilities and their application in materials science and technology research and education. (Author)

  17. The logic of comparative life history studies for estimating key parameters, with a focus on natural mortality rate

    Science.gov (United States)

    Hoenig, John M; Then, Amy Y.-H.; Babcock, Elizabeth A.; Hall, Norman G.; Hewitt, David A.; Hesp, Sybrand A.

    2016-01-01

    There are a number of key parameters in population dynamics that are difficult to estimate, such as natural mortality rate, intrinsic rate of population growth, and stock-recruitment relationships. Often, these parameters of a stock are, or can be, estimated indirectly on the basis of comparative life history studies. That is, the relationship between a difficult to estimate parameter and life history correlates is examined over a wide variety of species in order to develop predictive equations. The form of these equations may be derived from life history theory or simply be suggested by exploratory data analysis. Similarly, population characteristics such as potential yield can be estimated by making use of a relationship between the population parameter and bio-chemico–physical characteristics of the ecosystem. Surprisingly, little work has been done to evaluate how well these indirect estimators work and, in fact, there is little guidance on how to conduct comparative life history studies and how to evaluate them. We consider five issues arising in such studies: (i) the parameters of interest may be ill-defined idealizations of the real world, (ii) true values of the parameters are not known for any species, (iii) selecting data based on the quality of the estimates can introduce a host of problems, (iv) the estimates that are available for comparison constitute a non-random sample of species from an ill-defined population of species of interest, and (v) the hierarchical nature of the data (e.g. stocks within species within genera within families, etc., with multiple observations at each level) warrants consideration. We discuss how these issues can be handled and how they shape the kinds of questions that can be asked of a database of life history studies.

  18. Peer Mentoring for Undergraduates in a Research-Focused Diversity Initiative

    Science.gov (United States)

    Keller, Thomas E.; Logan, Kay; Lindwall, Jennifer; Beals, Caitlyn

    2017-01-01

    To provide multi-dimensional support for undergraduates from traditionally underrepresented backgrounds who aspire to careers in research, the BUILD EXITO project, part of a major NIH-funded diversity initiative, matches each scholar with three mentors: peer mentor (advanced student), career mentor (faculty adviser), and research mentor (research…

  19. The Focus of Current HCI Research in Usability Evaluation and Feedback

    DEFF Research Database (Denmark)

    Høegh, Rune Thaarup

    2007-01-01

    This paper presents the findings from a systematic literature study of the research on usability evaluation and feedback. The literature study covers the papers published from five key human-computer interaction journals for a period of four years, and depicts the most current research within...... the field with regard to usability evaluation and feedback....

  20. Geography should not be destiny: focusing HIV/AIDS implementation research and programs on microepidemics in US neighborhoods.

    Science.gov (United States)

    Nunn, Amy; Yolken, Annajane; Cutler, Blayne; Trooskin, Stacey; Wilson, Phill; Little, Susan; Mayer, Kenneth

    2014-05-01

    African Americans and Hispanics are disproportionately affected by the HIV/AIDS epidemic. Within the most heavily affected cities, a few neighborhoods account for a large share of new HIV infections. Addressing racial and economic disparities in HIV infection requires an implementation program and research agenda that assess the impact of HIV prevention interventions focused on increasing HIV testing, treatment, and retention in care in the most heavily affected neighborhoods in urban areas of the United States. Neighborhood-based implementation research should evaluate programs that focus on community mobilization, media campaigns, routine testing, linkage to and retention in care, and block-by-block outreach strategies.

  1. Focusing ethnography

    DEFF Research Database (Denmark)

    Woermann, Niklas

    2018-01-01

    underpinnings of focusing ethnographic research by comparing different schools of thought and suggesting a practice theory-based approach. It argues that many research projects are focused but do not reflect on the process of focusing, describes how to identify focal settings or practices, and introduces......Building theory with ethnography and filmic research increasingly requires focussing on key practices or settings, instead of painting a broad panorama of a culture. But few authors discuss why and how to focus. This article provides a systematic discussion of the theoretical and methodological...

  2. Researches focused on structure of aluminium alloys processed by rapid solidification, used in automotive industry

    International Nuclear Information System (INIS)

    Sfat, C.; Vasile, T.; Vasilescu, M.

    2001-01-01

    The paper present some new results focused on an aluminium high temperature alloy, obtained by 'melt spinning method'. alloy composition, processing conditions, resulted structures and the influence between them are presented. There are studied the two zone structures of the alloy and the relation between processing conditions and the characteristics of the zones, with implications on mechanical behavior in real conditions. The final conclusion show that is possible to control the structure in order to improve material behavior. (author)

  3. Contextualize that sort focus in the work and research training of the pedagogical career

    Directory of Open Access Journals (Sweden)

    David Ruiz-Ducasse

    2017-04-01

    Full Text Available This paper have purpose of perfecting continuous for learning and teaching process in the pedagogy careers, in this case, from a sort focus perspective. From development didactic of the labor investigative practice, he suggests idea about of the woman role. This work will let a change in the way proceeding of the professors’ future, to using the possibility that offer of the subject, for to guarantee a tally behaved and educate formation, which will let a first educate labor.

  4. FOCUS-GROUP AND ITS IMPACT IN THE QUESTIONNAIRE OF MARKETING RESEARCH ON THE ROMANIAN CAR MARKET

    Directory of Open Access Journals (Sweden)

    MANEA Constantin

    2010-12-01

    Full Text Available Designing a questionnaire is the most profound activity which makes an impact on a research in marketing. The investigation instrument finally determines the quality of this type of research. Never will a market research be able to exceed its questionnaire in point of quality. The present contribution succinctly itemizes a research project for the Romanian car market, emphasizing the importance of focus group, and appends, at the end, the concrete result, applied to the Romanian car market. The first part describes the hypotheses and sets out the objectives of the research, focusing on the market leader, i.e. Automobile Dacia Renault. The second section describes the practical process of designing the questionnaire, with a special stress laid on the impact of focus-group in the final version. The synthesis of focus group is materialized through a number of final remarks on the manner of concretely writing the questionnaire, which was put to practical use on the Romanian car market.

  5. Eastern forested watersheds: the OHER/ERD research focus at Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Reichle, D.E.

    1985-01-01

    An overview of the environmental research programs conducted at Oak Ridge National Laboratory (ORNL) under the auspices of the DOE Office of Health and Environmental Research (OHER) is presented. The research is focussed on the pathways of movement of chemicals from the atmosphere, through terrestrial environments, to receiving water bodies and the effects of these chemicals and other anthropogenic activities on biological systems and biogeochemical processes exposed during transport. Three fundamental levels of the environmental hierarchy are encompassed: process, system, and landscape. 5 refs

  6. Topical and Geographical Focus of Chinese Oceanographic Research - A Study of Trends in Publication

    National Research Council Canada - National Science Library

    Chu, Peter C; Li, Rongfeng

    2008-01-01

    .... Funds increase rapidly for education and scientific research. From 1993 to 2006, enrollment of full time students in universities and colleges grew from 924,000 to 5,400,000, total number of students (including part-time...

  7. Building Capacity in Community-Based Participatory Research Partnerships Through a Focus on Process and Multiculturalism.

    Science.gov (United States)

    Corbie-Smith, Giselle; Bryant, Angela R; Walker, Deborah J; Blumenthal, Connie; Council, Barbara; Courtney, Dana; Adimora, Ada

    2015-01-01

    In health research, investigators and funders are emphasizing the importance of collaboration between communities and academic institutions to achieve health equity. Although the principles underlying community-academic partnered research have been well-articulated, the processes by which partnerships integrate these principles when working across cultural differences are not as well described. We present how Project GRACE (Growing, Reaching, Advocating for Change and Empowerment) integrated participatory research principles with the process of building individual and partnership capacity. We worked with Vigorous Interventions In Ongoing Natural Settings (VISIONS) Inc., a process consultant and training organization, to develop a capacity building model. We present the conceptual framework and multicultural process of change (MPOC) that was used to build individual and partnership capacity to address health disparities. The process and capacity building model provides a common language, approach, and toolset to understand differences and the dynamics of inequity. These tools can be used by other partnerships in the conduct of research to achieve health equity.

  8. Postinfectious Functional Gastrointestinal Disorders: A Focus on Epidemiology and Research Agendas

    OpenAIRE

    Deising, Adam; Gutierrez, Ramiro L.; Porter, Chad K.; Riddle, Mark S.

    2013-01-01

    Epidemiologic research is fundamental and complementary to our understanding of disease and development of primary, secondary, and tertiary interventions. To put the current evidence into context and identify gaps and research priorities in the areas of disease attribution, burden of disease, clinical characterization, and management of postinfectious functional gastrointestinal disorders (PI-FGDs), we took a multidisciplinary approach from the domains of infectious disease, gastroenterology,...

  9. Focus on CSIR research in pollution waste: Water resource governance systems

    CSIR Research Space (South Africa)

    Rascher, J

    2007-08-01

    Full Text Available series of high level research programmes for ecosystem governance. These are illustrated in the fi gure below. The size of the individual circles indicates the priority attributed to the specifi c research theme by the symposium participants... Governance Socio-econ Define Economy of scale Context application Generic strategies/methods Link to democracy 3 Science Communication, learning & knowledge sharing 4 Integration of formal & traditional systems Hydrological boundaries Value...

  10. Improving wastewater-based epidemiology to estimate cannabis use : focus on the initial aspects of the analytical procedure

    NARCIS (Netherlands)

    Causanilles, A.; Baz-Lomba, J.A.; Burgard, D.A.; Emke, E.; González-Mariño, I.; Krizman-Matasic, I.; Li, A.; Löve, A.S.C.; McKall, A.K.; Montes, R.; van Nuijs, A.L.N.; Ort, C.; Quintana, J.B.; Senta, I.; Terzic, S.; Hernández, F.; de Voogt, P.; Bijlsma, L.

    2017-01-01

    Wastewater-based epidemiology is a promising and complementary tool for estimating drug use by the general population, based on the quantitative analysis of specific human metabolites of illicit drugs in urban wastewater. Cannabis is the most commonly used illicit drug and of high interest for

  11. Focused Ethnography as Research Method: A Case Study of Techno Music Producers in Home-Recording Studios

    Directory of Open Access Journals (Sweden)

    Jan Michael Kühn

    2013-05-01

    Full Text Available Translator's Introduction: Jan-Michael Kühn's essay introduces the reader to Hubert Knoblauch's focused ethnography [fokussierte Ethnographie] as an ethnographic fieldwork method. More than a decade after Knoblauch's first publications on this method, there are precious few guides to focused ethnography in the English language, save one (Knoblauch 2005. At any rate, there are certainly no introductions to this methodology that also use EDM scenes as a case study. Kühn's article was originally published in German in Soziologie Magazin, a student-run journal published from Martin Luther University in Halle (Saale but operated by an editorial network that spans Germany. As a result, Kühn orients his writing towards an audience of junior researchers, post-docs and graduate students, highlighting the ways in which focused ethnography suits the circumstances of early research careers, where one may have difficulty securing long-term research stays for fieldwork of broader scope. In particular, he notes that Knoblauch's methods require a very narrow scope for the project (i.e., a "field sector" rather than the whole field, a reliance on the researcher's previous knowledge of the field, and short bursts of intense ethnographic activity in order to create work that is tightly focused but still rigorous and generative of fresh knowledge and new concepts.KEYWORDS: qualitative methods; cultural production; music production; home-recording; technoculture

  12. Risk of Bias in Reports of In Vivo Research: A Focus for Improvement.

    Directory of Open Access Journals (Sweden)

    Malcolm R Macleod

    2015-10-01

    Full Text Available The reliability of experimental findings depends on the rigour of experimental design. Here we show limited reporting of measures to reduce the risk of bias in a random sample of life sciences publications, significantly lower reporting of randomisation in work published in journals of high impact, and very limited reporting of measures to reduce the risk of bias in publications from leading United Kingdom institutions. Ascertainment of differences between institutions might serve both as a measure of research quality and as a tool for institutional efforts to improve research quality.

  13. Organisation and management of research and development facilities - from cost to profit focus

    NARCIS (Netherlands)

    Kerssens-van Drongelen, I.C.; Pearson, Alan; Nixon, Bill

    2003-01-01

    In this publication, we present the main findings of a research project into differences in organisation, management and activities between R&D cost centres, semi-profit centres, profit centres, and independent R&D businesses. First, a theoretical framework is presented and then the empirical

  14. A Framework for Teaching Practice-Based Research with a Focus on Service Users

    Science.gov (United States)

    Austin, Michael J.; Isokuortti, Nanne

    2016-01-01

    The integration of research and practice in social work education and agency practice is both complex and challenging. The analysis presented here builds upon the classic social work generalist framework (engagement, assessment, service planning and implementation, service evaluation, and termination) by developing a three-part framework to…

  15. Integrating Program Assessment and a Career Focus into a Research Methods Course

    Science.gov (United States)

    Senter, Mary Scheuer

    2017-01-01

    Sociology research methods students in 2013 and 2016 implemented a series of "real world" data gathering activities that enhanced their learning while assisting the department with ongoing program assessment and program review. In addition to the explicit collection of program assessment data on both students' development of sociological…

  16. Plant invasions research in Latin America. Fast track to a more focused agenda

    Czech Academy of Sciences Publication Activity Database

    Gardener, M. R.; Bustamante, R.O.; Herrera, I.; Durigan, G.; Pivello, V.R.; Moro, M. F.; Stoll, A.; Langdon, B.; Baruch, Z.; Rico, Adriana; Arredondo-Nuńez, A.; Flores, S.

    2012-01-01

    Roč. 5, č. 2 (2012), s. 225-232 ISSN 1755-0874 Institutional research plan: CEZ:AV0Z60870520 Keywords : control * eradication * globalisation * inventories * novel ecosystem s * plant invasions * quarantine * Weed Risk Assessment Subject RIV: EH - Ecology, Behaviour Impact factor: 0.924, year: 2012

  17. "Just Imagine That…": A Solution Focused Approach to Doctoral Research Supervision in Health and Social Care

    Science.gov (United States)

    Walsh, Kenneth; Doherty, Kathleen; Andersen, Loretta; Bingham, Sharon; Crookes, Patrick; Ford, Karen; McSherry, Robert

    2018-01-01

    Effective supervision in doctoral research is critical to successful and timely completion. However, supervision is a complex undertaking with structural as well as relational challenges for both students and supervisors. This instructional paper describes an internationally applicable approach to supervision that we have developed in the health…

  18. NNSA Laboratory Directed Research and Development Program 2008 Symposium--Focus on Energy Security

    Energy Technology Data Exchange (ETDEWEB)

    Kotta, P R; Sketchley, J A

    2008-08-20

    The Laboratory Directed Research and Development (LDRD) Program was authorized by Congress in 1991 to fund leading-edge research and development central to the national laboratories core missions. LDRD anticipates and engages in projects on the forefront of science and engineering at the Department of Energy (DOE) national laboratories, and has a long history of addressing pressing national security needs at the National Nuclear Security Administration (NNSA) laboratories. LDRD has been a scientific success story, where projects continue to win national recognition for excellence through prestigious awards, papers published and cited in peer-reviewed journals, mainstream media coverage, and patents granted. The LDRD Program is also a powerful means to attract and retain top researchers from around the world, to foster collaborations with other prominent scientific and technological institutions, and to leverage some of the world's most technologically advanced assets. This enables the LDRD Program to invest in high-risk and potentially high-payoff research that creates innovative technical solutions for some of our nation's most difficult challenges. Worldwide energy demand is growing at an alarming rate, as developing nations continue to expand their industrial and economic base on the back of limited global resources. The resulting international conflicts and environmental consequences pose serious challenges not only to this nation, but to the international community as well. The NNSA and its national security laboratories have been increasingly called upon to devote their scientific and technological capabilities to help address issues that are not limited solely to the historic nuclear weapons core mission, but are more expansive and encompass a spectrum of national security missions, including energy security. This year's symposium highlights some of the exciting areas of research in alternative fuels and technology, nuclear power, carbon

  19. Recent problems in research on transition to adulthood: Country focus Serbia

    Directory of Open Access Journals (Sweden)

    Ignjatović Suzana

    2009-01-01

    Full Text Available The paper explores theoretical and methodological aspects of transition to adulthood. The concept is discussed within the framework of life course paradigm. The concept of transition to adulthood is operationalized as four dimensions: family transition, professional (career transition, financial status transition and housing transition. We discuss in detail the process of becoming an adult in Serbian society. The thesis of specific type of transition to adulthood, named prolonged adolescence, has been fully examined. The analysis is based on data collected in a survey (2003 of young people aged 17-35. In the paper we focus on the sub sample of respondents aged 34-35 being a post-transitional cohort. The 34-35 cohort trajectory to adulthood is explored as an indicator of general trend in transition to adulthood in a period of radical social turmoil. .

  20. Status quo and future research challenges on organic food quality determination with focus on laboratory methods.

    Science.gov (United States)

    Kahl, Johannes; Bodroza-Solarov, Marija; Busscher, Nicolaas; Hajslova, Jana; Kneifel, Wolfgang; Kokornaczyk, Maria Olga; van Ruth, Saskia; Schulzova, Vera; Stolz, Peter

    2014-10-01

    Organic food quality determination needs multi-dimensional evaluation tools. The main focus is on the authentication as an analytical verification of the certification process. New fingerprinting approaches such as ultra-performance liquid chromatography-mass spectrometry, gas chromatography-mass spectrometry, direct analysis in real time-high-resolution mass spectrometry as well as crystallization with and without the presence of additives seem to be promising methods in terms of time of analysis and detecting organic system-related parameters. For further methodological development, a system approach is recommended, which also takes into account food structure aspects. Furthermore, the authentication of processed organic samples needs more consciousness, hence most of organic food is complex and processed. © 2013 Society of Chemical Industry.

  1. The Future of Research on Evidence-based Developmental Violence Prevention in Europe – Introduction to the Focus Section

    Directory of Open Access Journals (Sweden)

    Manuel Eisner

    2012-12-01

    Full Text Available Across Europe, there is an increasing demand for good evidence that can inform policies aimed at reducing violence against and among children and adolescents. However, there is still a paucity of high-quality research on effective prevention of bullying and violence, and researchers from different parts of Europe rarely discuss their findings. The focus section of this issue of the International Journal of Conflict and Violence brings together work by prominent preventionscholars from across Europe, who show that significant progress is being made. The introduction presents nine recommendations about how prevention research could be further strengthened in Europe.

  2. A European Perspective on Auditory Processing Disorder-Current Knowledge and Future Research Focus

    DEFF Research Database (Denmark)

    IIiadou, Vasiliki; Ptok, Martin; Grech, Helen

    2017-01-01

    Current notions of "hearing impairment," as reflected in clinical audiological practice, do not acknowledge the needs of individuals who have normal hearing pure tone sensitivity but who experience auditory processing difficulties in everyday life that are indexed by reduced performance in other...... of diseases as H93.25 and in the forthcoming beta eleventh version. APDs may have detrimental effects on the affected individual, with low esteem, anxiety, and depression, and symptoms may remain into adulthood. These disorders may interfere with learning per se and with communication, social, emotional......, and academic-work aspects of life. The objective of the present paper is to define a baseline European APD consensus formulated by experienced clinicians and researchers in this specific field of human auditory science. A secondary aim is to identify issues that future research needs to address in order...

  3. Research on long-lived radioactive waste management: focus on environmental issues

    International Nuclear Information System (INIS)

    Andre Jehan, R.

    1994-01-01

    Studies are in progress on deep geologic media to examine their potential for retrievable or non retrievable nuclear waste disposal. The primary objective of site investigations and experiments for the coming years will be the development of underground laboratories (observation of host rocks and fluids). Geologic research programs are designed to investigate the potential for deep construction and the ability of the underground media to isolate radioelements from the biosphere. Researches covered the following topics: understanding the media likely to be found in underground laboratories using 3-D geologic modelling; predicting the materials behaviour under various mechanical, thermal and radiation loadings; describing fluid transfers through the geosphere and assessing radioactive materials transport and/or blockage by understanding the multiple geochemical mechanisms involved. The geologic and climatic long term behaviours are also taken into account. (author). 13 figs

  4. Text data extraction for a prospective, research-focused data mart: implementation and validation.

    Science.gov (United States)

    Hinchcliff, Monique; Just, Eric; Podlusky, Sofia; Varga, John; Chang, Rowland W; Kibbe, Warren A

    2012-09-13

    Translational research typically requires data abstracted from medical records as well as data collected specifically for research. Unfortunately, many data within electronic health records are represented as text that is not amenable to aggregation for analyses. We present a scalable open source SQL Server Integration Services package, called Regextractor, for including regular expression parsers into a classic extract, transform, and load workflow. We have used Regextractor to abstract discrete data from textual reports from a number of 'machine generated' sources. To validate this package, we created a pulmonary function test data mart and analyzed the quality of the data mart versus manual chart review. Eleven variables from pulmonary function tests performed closest to the initial clinical evaluation date were studied for 100 randomly selected subjects with scleroderma. One research assistant manually reviewed, abstracted, and entered relevant data into a database. Correlation with data obtained from the automated pulmonary function test data mart within the Northwestern Medical Enterprise Data Warehouse was determined. There was a near perfect (99.5%) agreement between results generated from the Regextractor package and those obtained via manual chart abstraction. The pulmonary function test data mart has been used subsequently to monitor disease progression of patients in the Northwestern Scleroderma Registry. In addition to the pulmonary function test example presented in this manuscript, the Regextractor package has been used to create cardiac catheterization and echocardiography data marts. The Regextractor package was released as open source software in October 2009 and has been downloaded 552 times as of 6/1/2012. Collaboration between clinical researchers and biomedical informatics experts enabled the development and validation of a tool (Regextractor) to parse, abstract and assemble structured data from text data contained in the electronic health

  5. Text data extraction for a prospective, research-focused data mart: implementation and validation

    Directory of Open Access Journals (Sweden)

    Hinchcliff Monique

    2012-09-01

    Full Text Available Abstract Background Translational research typically requires data abstracted from medical records as well as data collected specifically for research. Unfortunately, many data within electronic health records are represented as text that is not amenable to aggregation for analyses. We present a scalable open source SQL Server Integration Services package, called Regextractor, for including regular expression parsers into a classic extract, transform, and load workflow. We have used Regextractor to abstract discrete data from textual reports from a number of ‘machine generated’ sources. To validate this package, we created a pulmonary function test data mart and analyzed the quality of the data mart versus manual chart review. Methods Eleven variables from pulmonary function tests performed closest to the initial clinical evaluation date were studied for 100 randomly selected subjects with scleroderma. One research assistant manually reviewed, abstracted, and entered relevant data into a database. Correlation with data obtained from the automated pulmonary function test data mart within the Northwestern Medical Enterprise Data Warehouse was determined. Results There was a near perfect (99.5% agreement between results generated from the Regextractor package and those obtained via manual chart abstraction. The pulmonary function test data mart has been used subsequently to monitor disease progression of patients in the Northwestern Scleroderma Registry. In addition to the pulmonary function test example presented in this manuscript, the Regextractor package has been used to create cardiac catheterization and echocardiography data marts. The Regextractor package was released as open source software in October 2009 and has been downloaded 552 times as of 6/1/2012. Conclusions Collaboration between clinical researchers and biomedical informatics experts enabled the development and validation of a tool (Regextractor to parse, abstract and assemble

  6. Advances in Proteomic Techniques for Cytokine Analysis: Focus on Melanoma Research

    Czech Academy of Sciences Publication Activity Database

    Kupcová Skalníková, Helena; Čížková, Jana; Červenka, Jakub; Vodička, Petr

    2017-01-01

    Roč. 18, č. 12 (2017), č. článku 2697. E-ISSN 1422-0067 R&D Projects: GA ČR GA16-05534S; GA MŠk(CZ) LO1609 Institutional support: RVO:67985904 Keywords : cytokine * cancer * melanoma * secretome * proteomics Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Biochemical research methods Impact factor: 3.226, year: 2016

  7. Easily configured real-time CPOE Pick Off Tool supporting focused clinical research and quality improvement.

    Science.gov (United States)

    Rosenbaum, Benjamin P; Silkin, Nikolay; Miller, Randolph A

    2014-01-01

    Real-time alerting systems typically warn providers about abnormal laboratory results or medication interactions. For more complex tasks, institutions create site-wide 'data warehouses' to support quality audits and longitudinal research. Sophisticated systems like i2b2 or Stanford's STRIDE utilize data warehouses to identify cohorts for research and quality monitoring. However, substantial resources are required to install and maintain such systems. For more modest goals, an organization desiring merely to identify patients with 'isolation' orders, or to determine patients' eligibility for clinical trials, may adopt a simpler, limited approach based on processing the output of one clinical system, and not a data warehouse. We describe a limited, order-entry-based, real-time 'pick off' tool, utilizing public domain software (PHP, MySQL). Through a web interface the tool assists users in constructing complex order-related queries and auto-generates corresponding database queries that can be executed at recurring intervals. We describe successful application of the tool for research and quality monitoring.

  8. Regularization parameter estimation for underdetermined problems by the χ 2 principle with application to 2D focusing gravity inversion

    International Nuclear Information System (INIS)

    Vatankhah, Saeed; Ardestani, Vahid E; Renaut, Rosemary A

    2014-01-01

    The χ 2 principle generalizes the Morozov discrepancy principle to the augmented residual of the Tikhonov regularized least squares problem. For weighting of the data fidelity by a known Gaussian noise distribution on the measured data, when the stabilizing, or regularization, term is considered to be weighted by unknown inverse covariance information on the model parameters, the minimum of the Tikhonov functional becomes a random variable that follows a χ 2 -distribution with m+p−n degrees of freedom for the model matrix G of size m×n, m⩾n, and regularizer L of size p × n. Then, a Newton root-finding algorithm, employing the generalized singular value decomposition, or singular value decomposition when L = I, can be used to find the regularization parameter α. Here the result and algorithm are extended to the underdetermined case, m 2 algorithms when m 2 and unbiased predictive risk estimator of the regularization parameter are used for the first time in this context. For a simulated underdetermined data set with noise, these regularization parameter estimation methods, as well as the generalized cross validation method, are contrasted with the use of the L-curve and the Morozov discrepancy principle. Experiments demonstrate the efficiency and robustness of the χ 2 principle and unbiased predictive risk estimator, moreover showing that the L-curve and Morozov discrepancy principle are outperformed in general by the other three techniques. Furthermore, the minimum support stabilizer is of general use for the χ 2 principle when implemented without the desirable knowledge of the mean value of the model. (paper)

  9. The quality of Australian Indigenous primary health care research focusing on social and emotional wellbeing: a systematic review.

    Science.gov (United States)

    Farnbach, Sara; Eades, Anne-Maree; Fernando, Jamie K; Gwynn, Josephine D; Glozier, Nick; Hackett, Maree L

    2017-10-11

    Objectives and importance of the study: Primary health care research focused on Aboriginal and Torres Strait Islander (Indigenous) people is needed to ensure that key frontline services provide evidence based and culturally appropriate care. We systematically reviewed the published primary health care literature to identify research designs, processes and outcomes, and assess the scientific quality of research focused on social and emotional wellbeing. This will inform future research to improve evidence based, culturally appropriate primary health care. Systematic review in accordance with PRISMA and MOOSE guidelines. Four databases and one Indigenous-specific project website were searched for qualitative, quantitative and mixed-method published research. Studies that were conducted in primary health care services and focused on the social and emotional wellbeing of Indigenous people were included. Scientific quality was assessed using risk-of-bias assessment tools that were modified to meet our aims. We assessed community acceptance by identifying the involvement of community governance structures and representation during research development, conduct and reporting. Data were extracted using standard forms developed for this review. We included 32 articles, which reported on 25 studies. Qualitative and mixed methods were used in 18 studies. Twelve articles were judged as high or unclear risk of bias, four as moderate and five as low risk of bias. Another four studies were not able to be assessed as they did not align with the risk-of-bias tools. Of the five articles judged as low risk of bias, two also had high community acceptance and both of these were qualitative. One used a phenomenological approach and the other combined participatory action research with a social-ecological perspective and incorporated 'two-way learning' principles. Of the 16 studies where a primary outcome was identified, eight aimed to identify perceptions or experiences. The

  10. The quality of Australian Indigenous primary health care research focusing on social and emotional wellbeing: a systematic review

    Directory of Open Access Journals (Sweden)

    Sara Farnbach

    2017-10-01

    Full Text Available Objectives and importance of the study: Primary health care research focused on Aboriginal and Torres Strait Islander (Indigenous people is needed to ensure that key frontline services provide evidence based and culturally appropriate care. We systematically reviewed the published primary health care literature to identify research designs, processes and outcomes, and assess the scientific quality of research focused on social and emotional wellbeing. This will inform future research to improve evidence based, culturally appropriate primary health care. Study type: Systematic review in accordance with PRISMA and MOOSE guidelines. Methods: Four databases and one Indigenous-specific project website were searched for qualitative, quantitative and mixed-method published research. Studies that were conducted in primary health care services and focused on the social and emotional wellbeing of Indigenous people were included. Scientific quality was assessed using risk-of-bias assessment tools that were modified to meet our aims. We assessed community acceptance by identifying the involvement of community governance structures and representation during research development, conduct and reporting. Data were extracted using standard forms developed for this review. Results: We included 32 articles, which reported on 25 studies. Qualitative and mixed methods were used in 18 studies. Twelve articles were judged as high or unclear risk of bias, four as moderate and five as low risk of bias. Another four studies were not able to be assessed as they did not align with the risk-of-bias tools. Of the five articles judged as low risk of bias, two also had high community acceptance and both of these were qualitative. One used a phenomenological approach and the other combined participatory action research with a social–ecological perspective and incorporated ‘two-way learning’ principles. Of the 16 studies where a primary outcome was identified, eight aimed

  11. A Family-Focused Delirium Educational Initiative With Practice and Research Implications.

    Science.gov (United States)

    Paulson, Christina May; Monroe, Todd; McDougall, Graham J; Fick, Donna M

    2016-01-01

    Delirium is burdensome and psychologically distressing for formal and informal caregivers, yet family caregivers often have very little understanding or knowledge about delirium. As part of a large multisite intervention study, the Early Nurse Detection of Delirium Superimposed on Dementia (END-DSD), the authors identified a need for family educational materials. This educational initiative's purpose was to develop a delirium admission brochure for family members to aid in the prevention and earlier identification of delirium during hospitalization. A brochure was developed using an iterative approach with an expert panel. Following three iterations, a final brochure was approved. The authors found that an iterative expert consensus approach can be used to develop a brochure for families. Major content areas were helping families understand the difference between delirium and dementia, signs and symptoms of delirium, causes of delirium, and strategies family members can use to prevent delirium. A caregiver-focused educational brochure is one intervention to use in targeting older adults hospitalized with delirium.

  12. The need for a behavioural science focus in research on mental health and mental disorders.

    Science.gov (United States)

    Wittchen, Hans-Ulrich; Knappe, Susanne; Andersson, Gerhard; Araya, Ricardo; Banos Rivera, Rosa M; Barkham, Michael; Bech, Per; Beckers, Tom; Berger, Thomas; Berking, Matthias; Berrocal, Carmen; Botella, Christina; Carlbring, Per; Chouinard, Guy; Colom, Francesc; Csillag, Claudio; Cujipers, Pim; David, Daniel; Emmelkamp, Paul M G; Essau, Cecilia A; Fava, Giovanni A; Goschke, Thomas; Hermans, Dirk; Hofmann, Stefan G; Lutz, Wolfgang; Muris, Peter; Ollendick, Thomas H; Raes, Filip; Rief, Winfried; Riper, Heleen; Tossani, Eliana; van der Oord, Saskia; Vervliet, Bram; Haro, Josep M; Schumann, Gunter

    2014-01-01

    Psychology as a science offers an enormous diversity of theories, principles, and methodological approaches to understand mental health, abnormal functions and behaviours and mental disorders. A selected overview of the scope, current topics as well as strength and gaps in Psychological Science may help to depict the advances needed to inform future research agendas specifically on mental health and mental disorders. From an integrative psychological perspective, most maladaptive health behaviours and mental disorders can be conceptualized as the result of developmental dysfunctions of psychological functions and processes as well as neurobiological and genetic processes that interact with the environment. The paper presents and discusses an integrative translational model, linking basic and experimental research with clinical research as well as population-based prospective-longitudinal studies. This model provides a conceptual framework to identify how individual vulnerabilities interact with environment over time, and promote critical behaviours that might act as proximal risk factors for ill-health and mental disorders. Within the models framework, such improved knowledge is also expected to better delineate targeted preventive and therapeutic interventions that prevent further escalation in early stages before the full disorder and further complications thereof develop. In contrast to conventional "personalized medicine" that typically targets individual (genetic) variation of patients who already have developed a disease to improve medical treatment, the proposed framework model, linked to a concerted funding programme of the "Science of Behaviour Change", carries the promise of improved diagnosis, treatment and prevention of health-risk behaviour constellations as well as mental disorders. Copyright © 2013 John Wiley & Sons, Ltd.

  13. Strategies to control costs and quality: a focus on outcomes research for disease management.

    Science.gov (United States)

    Villagra, Victor

    2004-04-01

    Rapid adoption of disease management has outpaced systematic evaluation of its net value in improving health outcomes and mitigating healthcare cost. This article identifies areas in which outcomes research in disease management is needed to demonstrate its value or to enhance its performance. Patient identification for disease management relies on administrative database queries but the trade-offs in sensitivity, specificity, and predictive value of alternative queries are not well known. Large-scale deployment, rapid patient engagement, and repeated interactions between patients and nurses could be important attributes for attaining measurable improvements in quality and cost reduction over short periods of time, but these hypothesis need to be tested. There is a trend toward integration of multiple chronic disease management programs onto a single platform. To support this trend, there is a need for a corresponding set of integrated clinical guidelines or "meta-guidelines" that combine the contents of individual practice guidelines. The relative contribution of various disease management interventions in improving clinical results, lowering costs, and their respective ease of implementation is not known. Research leading to a better understanding of tradeoffs could lead to more rational resource allocation and better overall outcomes. Coordination between disease management programs and physician practices is lacking. Research aimed at defining operational and technical interfaces and cultural and behavioral professional adjustments necessary to achieve integration and coordination is needed. The lack of a consistent analytical framework for evaluating clinical and financial outcomes has made comparisons of reported results impossible and has rendered many reports unreliable. Theoretical work on a standard methodology that integrates clinical and financial outcomes and empiric validation is needed.

  14. Mexican medicinal plants with anxiolytic or antidepressant activity: Focus on preclinical research.

    Science.gov (United States)

    López-Rubalcava, Carolina; Estrada-Camarena, Erika

    2016-06-20

    Anxiety and depression are considered the most prevalent psychiatric disorders worldwide. In Mexico, the use of medicinal plants to alleviate the symptoms associated with these psychiatric disorders is increasing. However, there is little scientific evidence that validates the efficacy of these plants. This evidence needs to be critically revised, and further studied to provided scientific support for their use. To identify the plants that are used in Mexico for the treatment of disorders related to anxiety and depression, and to review the current preclinical and when available, clinical information of these plants. We searched in scientific databases (Pubmed, Web of Science, Scopus and other web sources such as "Biblioteca digital de la medicina tradicional Mexicana" ) for Mexican plants used for the treatment of anxiety and depression that have been analyzed in preclinical studies. Additional information was obtained from published books. For this review, we also consider those plants used in Mexican traditional medicine for the treatment of "nervios," "susto" or "espanto;" common terms that describe symptoms related to anxiety and depression disorders. The bibliographic search identified 49 plants used in Mexican traditional medicine for the treatment of disorders related to anxiety and depression. From all these plants, 59% were analyzed in preclinical research, and only 8% were tested in clinical studies; only a few of these studies tried to elucidate their mechanism of action. In general, it is proposed that the plant extracts interact with the GABAergic system. However, only part of these studies attempted to analyze other neurotransmitter systems. Finally, in some cases, drug-herbal interactions were reported. There is a large number of Mexican medicinal plants used as a treatment for anxiety and depression disorders. Although some of these plants have been studied in preclinical research, in most cases these studies are preliminary, and the understanding

  15. Transit forecasting accuracy : ridership forecasts and capital cost estimates, final research report.

    Science.gov (United States)

    2009-01-01

    In 1992, Pickrell published a seminal piece examining the accuracy of ridership forecasts and capital cost estimates for fixed-guideway transit systems in the US. His research created heated discussions in the transit industry regarding the ability o...

  16. Focusing on What Counts: Using Exploratory Focus Groups to Enhance the Development of an Electronic Survey in a Mixed-Methods Research Design

    Science.gov (United States)

    Galliott, Natal'ya; Graham, Linda J.

    2016-01-01

    This paper illustrates the use of exploratory focus groups to inform the development of a survey instrument in a sequential phase mixed-methods study investigating differences in secondary students' career choice capability. Five focus groups were conducted with 23 Year 10 students in the state of New South Wales, Australia. Analysis of the focus…

  17. Risk-avoidance or utmost commitment. : Dutch focus group research on views on cohabitation and marriage.

    Directory of Open Access Journals (Sweden)

    Renske Keizer

    2015-02-01

    Full Text Available Background: Dutch adults grew up in a highly individualized country, characterized by high divorce rates, which may have influenced their views on cohabitation and marriage. Objective: We examine Dutch adults' perceptions of how similar or different cohabitation and marriage are, whether they believe that cohabitation would be a strategy to avoid the risk of divorce, as well as their views on why people marry in individualized societies. Methods: We analyze seven focus group interviews with 40 Dutch participants, collected in 2012 in Rotterdam, the Netherlands. Results: Many participants discussed differences and similarities between cohabitation and marriage in a context of high divorce rates, and frequently viewed cohabitation as a risk-reduction strategy. At the same time, marriage was often seen as ―the real deal‖, in terms of legal arrangements, but also as a symbol of utmost commitment. Less educated participants viewed more financial advantages in cohabitation compared to marriage, and felt more strongly about the symbolic value of marriage than their highly educated counterparts. There was strong consensus that there is not, and should not be, a social norm to marry. Conclusions: In a context of high relationship instability, cohabitation has become a risk-reduction strategy. When norms to marry are weak, people may marry in order to emphasize the uniqueness of their relationship. However, the individualistic nature of Dutch society is mirrored in respondents' reluctance to set standards or proscribe norms on why and when to marry and their emphasis that cohabitation can also imply high levels of commitment.

  18. Teaching research ethics better: focus on excellent science, not bad scientists.

    Science.gov (United States)

    Yarborough, Mark; Hunter, Lawrence

    2013-06-01

    A recent report of the United States' Presidential Commission for the Study of Bioethical Issues highlights how important it is for the research community to enjoy the "earned confidence" of the public and how creating a "culture of responsibility" can contribute to that confidence. It identifies a major role for "creative, flexible, and innovative" ethics education in creating such a culture. Other recent governmental reports from various nations similarly call for a renewed emphasis on ethics education in the sciences. We discuss why some common approaches to ethics education in the graduate sciences fail to meet the goals envisioned in the reports and we describe an approach, animated by primary attention on excellent science as opposed to bad scientists, that we have employed in our ethics teaching that we think is better suited for inspiring and sustaining responsible, trustworthy science. © 2013 Wiley Periodicals, Inc.

  19. The need for a behavioural science focus in research on mental health and mental disorders

    DEFF Research Database (Denmark)

    Wittchen, Hans-Ulrich; Knappe, Susanne; Andersson, Gerhard

    2014-01-01

    of patients who already have developed a disease to improve medical treatment, the proposed framework model, linked to a concerted funding programme of the "Science of Behaviour Change", carries the promise of improved diagnosis, treatment and prevention of health-risk behaviour constellations as well......Psychology as a science offers an enormous diversity of theories, principles, and methodological approaches to understand mental health, abnormal functions and behaviours and mental disorders. A selected overview of the scope, current topics as well as strength and gaps in Psychological Science may...... help to depict the advances needed to inform future research agendas specifically on mental health and mental disorders. From an integrative psychological perspective, most maladaptive health behaviours and mental disorders can be conceptualized as the result of developmental dysfunctions...

  20. Using Focus Groups to Research Sensitive Issues: Insights from Group Interviews on Nursing in the Northern Ireland “Troubles”

    Directory of Open Access Journals (Sweden)

    Joanne Jordan

    2007-12-01

    Full Text Available In this article the authors discuss the usefulness of focus groups for researching sensitive issues using evidence from a study examining the experiences of nurses providing care in the context of the Northern Ireland Troubles. They conducted three group interviews with nurses during which they asked about the issues the nurses face(d in providing nursing care amid enduring social division. Through a discursive analysis of within-group interaction, they demonstrate how participants employ a range of interpretive resources, the effect of which is to prioritize particular knowledge concerning the nature of nursing care. The identification of such patterned activity highlights the ethnographic value of focus groups to reveal social conventions guiding the production of accounts but also suggests that accounts cannot be divorced from the circumstances of their production. Consequently, the authors argue that focus groups should be considered most useful for illuminating locally sanctioned ways of talking about sensitive issues.

  1. English Water Meadows: historic relics or focus for environmental management and inter-disciplinary research?

    Science.gov (United States)

    Cook, Hadrian

    2015-04-01

    Irrigated water meadows are found across Europe, from southern Scandinavia to Spain and in the Alpine regions and Italy. While the practice of engineering 'floated' meadow land for deliberate irrigation on hillsides and floodplains is widespread and ancient, since about 1600 AD the practice was widely adopted on floodplains in southern England where they improved the timing and productivity of grazing land and produced hay crops. They also became a part of English consciousness through art and literature. To some, water meadows are a relic of an agrarian past, to others they are the object of a range of foci for conservation, education, sustainable grass production, community engagement and recent research suggests water returned from meadow irrigation is beneficial to river water quality. Historically floodplain 'bedwork' water meadows grew from, and were integral in, the farming system of 'Wessex' involving sheep which produced dung for arable land and later supporting dairy and beef production, as well as hay. Where systems remain, this is largely due to the whim of individuals, the outcome of agri-environmental schemes. Water meadows may be managed by public, voluntary or private sector bodies. What is needed is a fresh look at how land owners, or communities, might micro-target them for heritage, habitat and grassland management. There are therefore interesting questions concerning their future: Who might invest in their restoration and maintenance? How might they be integrated into commercial farming? Are they of sufficient interest to restore en masse to become (once more) a major feature of the English chalk stream valleys? Do they provide a way into academic and public perception, combining environmental science, history, cultural heritage and environmental management? How might restoration and management become vehicles for public engagement? While each of these questions represents a major topic for discussion, this paper is an attempt to consolidate

  2. THE EDUCATIONAL RESEARCH ON THE WEB – A TWO-EDGED TOOL IN FOCUS

    Directory of Open Access Journals (Sweden)

    R.M. Lima

    2006-07-01

    Full Text Available Although  the  use  of  the  internet  is  expanding  rapidly  on  college  campuses,  little  is  known  about  student internet  use,  how  students  perceive  the  reality of  internet  information and  how successful they  are  in  searching  the internet.  The  aim  of  this  project  is  to  analyze  the  biochemical  issues  available  in  web  pages,  evaluating  contents quality,  trustworthiness  and  effectiveness.  Fourteen  sites  were  analyzed  regarding  to  contents,  presence  of bibliographical  references,  authorship,  titles  responsibility  and  adequacy  to  target  public.  The  great  majority  did  not mention  bibliographic  references  and  target  public.  Less  than  half  of  the  researched  sites  divulged  names  and/or graduation  status  of  information providers.  Some  sites  contained  critical  conceptual  errors,  such  as:  participation  of H2O  in  the  photosynthesis  dark  phase,  carnivore  animals  feeding  only  on  herbivores,  the  overall  equation  of photosynthesis with errors, NADH2 instead NAD+, etc. Half of them presented identical texts and figures. None of the analyzed  sites  was  thus  considered  excellent.  Our  data  strengthen  the  need  for  rigorous  evaluation  concerning  to educational research of biochemical themes on the web.

  3. On Moderator Detection in Anchoring Research: Implications of Ignoring Estimate Direction

    Directory of Open Access Journals (Sweden)

    Nathan N. Cheek

    2018-05-01

    Full Text Available Anchoring, whereby judgments assimilate to previously considered standards, is one of the most reliable effects in psychology. In the last decade, researchers have become increasingly interested in identifying moderators of anchoring effects. We argue that a drawback of traditional moderator analyses in the standard anchoring paradigm is that they ignore estimate direction—whether participants’ estimates are higher or lower than the anchor value. We suggest that failing to consider estimate direction can sometimes obscure moderation in anchoring tasks, and discuss three potential analytic solutions that take estimate direction into account. Understanding moderators of anchoring effects is essential for a basic understanding of anchoring and for applied research on reducing the influence of anchoring in real-world judgments. Considering estimate direction reduces the risk of failing to detect moderation.

  4. Utilizing the ratio and the summation of two spectral lines for estimation of optical depth: Focus on thick plasmas

    Science.gov (United States)

    Rezaei, Fatemeh; Tavassoli, Seyed Hassan

    2016-11-01

    In this paper, a study is performed on the spectral lines of plasma radiations created from focusing of the Nd:YAG laser on Al standard alloys at atmospheric air pressure. A new theoretical method is presented to investigate the evolution of the optical depth of the plasma based on the radiative transfer equation, in LTE condition. This work relies on the Boltzmann distribution, lines broadening equations, and as well as the self-absorption relation. Then, an experimental set-up is devised to extract some of plasma parameters such as temperature from modified line ratio analysis, electron density from Stark broadening mechanism, line intensities of two spectral lines in the same order of ionization from similar species, and the plasma length from the shadowgraphy section. In this method, the summation and the ratio of two spectral lines are considered for evaluation of the temporal variations of the plasma parameters in a LIBS homogeneous plasma. The main advantage of this method is that it comprises the both of thin and thick laser induced plasmas without straight calculation of self-absorption coefficient. Moreover, the presented model can also be utilized for evaluation the transition of plasma from the thin condition to the thick one. The results illustrated that by measuring the line intensities of two spectral lines at different evolution times, the plasma cooling and the growth of the optical depth can be followed.

  5. Understanding public opinion in debates over biomedical research: looking beyond political partisanship to focus on beliefs about science and society.

    Directory of Open Access Journals (Sweden)

    Matthew Nisbet

    Full Text Available As social scientists have investigated the political and social factors influencing public opinion in science-related policy debates, there has been growing interest in the implications of this research for public communication and outreach. Given the level of political polarization in the United States, much of the focus has been on partisan differences in public opinion, the strategies employed by political leaders and advocates that promote those differences, and the counter-strategies for overcoming them. Yet this focus on partisan differences tends to overlook the processes by which core beliefs about science and society impact public opinion and how these schema are often activated by specific frames of reference embedded in media coverage and popular discourse. In this study, analyzing cross-sectional, nationally representative survey data collected between 2002 and 2010, we investigate the relative influence of political partisanship and science-related schema on Americans' support for embryonic stem cell research. In comparison to the influence of partisan identity, our findings suggest that generalized beliefs about science and society were more chronically accessible, less volatile in relation to media attention and focusing events, and an overall stronger influence on public opinion. Classifying respondents into four unique audience groups based on their beliefs about science and society, we additionally find that individuals within each of these groups split relatively evenly by partisanship but differ on other important dimensions. The implications for public engagement and future research on controversies related to biomedical science are discussed.

  6. Understanding public opinion in debates over biomedical research: looking beyond political partisanship to focus on beliefs about science and society.

    Science.gov (United States)

    Nisbet, Matthew; Markowitz, Ezra M

    2014-01-01

    As social scientists have investigated the political and social factors influencing public opinion in science-related policy debates, there has been growing interest in the implications of this research for public communication and outreach. Given the level of political polarization in the United States, much of the focus has been on partisan differences in public opinion, the strategies employed by political leaders and advocates that promote those differences, and the counter-strategies for overcoming them. Yet this focus on partisan differences tends to overlook the processes by which core beliefs about science and society impact public opinion and how these schema are often activated by specific frames of reference embedded in media coverage and popular discourse. In this study, analyzing cross-sectional, nationally representative survey data collected between 2002 and 2010, we investigate the relative influence of political partisanship and science-related schema on Americans' support for embryonic stem cell research. In comparison to the influence of partisan identity, our findings suggest that generalized beliefs about science and society were more chronically accessible, less volatile in relation to media attention and focusing events, and an overall stronger influence on public opinion. Classifying respondents into four unique audience groups based on their beliefs about science and society, we additionally find that individuals within each of these groups split relatively evenly by partisanship but differ on other important dimensions. The implications for public engagement and future research on controversies related to biomedical science are discussed.

  7. Understanding Public Opinion in Debates over Biomedical Research: Looking beyond Political Partisanship to Focus on Beliefs about Science and Society

    Science.gov (United States)

    Nisbet, Matthew; Markowitz, Ezra M.

    2014-01-01

    As social scientists have investigated the political and social factors influencing public opinion in science-related policy debates, there has been growing interest in the implications of this research for public communication and outreach. Given the level of political polarization in the United States, much of the focus has been on partisan differences in public opinion, the strategies employed by political leaders and advocates that promote those differences, and the counter-strategies for overcoming them. Yet this focus on partisan differences tends to overlook the processes by which core beliefs about science and society impact public opinion and how these schema are often activated by specific frames of reference embedded in media coverage and popular discourse. In this study, analyzing cross-sectional, nationally representative survey data collected between 2002 and 2010, we investigate the relative influence of political partisanship and science-related schema on Americans' support for embryonic stem cell research. In comparison to the influence of partisan identity, our findings suggest that generalized beliefs about science and society were more chronically accessible, less volatile in relation to media attention and focusing events, and an overall stronger influence on public opinion. Classifying respondents into four unique audience groups based on their beliefs about science and society, we additionally find that individuals within each of these groups split relatively evenly by partisanship but differ on other important dimensions. The implications for public engagement and future research on controversies related to biomedical science are discussed. PMID:24558393

  8. Estimating study costs for use in VOI, a study of dutch publicly funded drug related research

    NARCIS (Netherlands)

    Van Asselt, A.D.; Ramaekers, B.L.; Corro Ramos, I.; Joore, M.A.; Al, M.J.; Lesman-Leegte, I.; Postma, M.J.; Vemer, P.; Feenstra, T.F.

    2016-01-01

    Objectives: To perform value of information (VOI) analyses, an estimate of research costs is needed. However, reference values for such costs are not available. This study aimed to analyze empirical data on research budgets and, by means of a cost tool, provide an overview of costs of several types

  9. Medical research and audit skills training for undergraduates: an international analysis and student-focused needs assessment.

    Science.gov (United States)

    2018-01-01

    Interpreting, performing and applying research is a key part of evidence-based medical practice, however, incorporating these within curricula is challenging. This study aimed to explore current provision of research skills training within medical school curricula, provide a student-focused needs assessment and prioritise research competencies. A international, cross-sectional survey of final year UK and Irish medical students was disseminated at each participating university. The questionnaire investigated research experience, and confidence in the Medical Education in Europe (MEDINE) 2 consensus survey research competencies. Fully completed responses were received from 521 final year medical students from 32 medical schools (43.4% male, mean age 24.3 years). Of these, 55.3% had an additional academic qualification (49.5% Bachelor's degree), and 38.8% had been a named author on an academic publication. Considering audit and research opportunities and teaching experience, 47.2% reported no formal audit training compared with 27.1% who reported no formal research training. As part of their medical school course, 53.4% had not performed an audit, compared with 29.9% who had not participated in any clinical or basic science research. Nearly a quarter of those who had participated in research reported doing so outside of their medical degree course. Low confidence areas included selecting and performing the appropriate statistical test, selecting the appropriate research method, and critical appraisal. Following adjustment, several factors were associated with increased confidence including previous clinical research experience (OR 4.21, 2.66 to 6.81, Paudit skills training in the curriculum (OR 1.52, 1.03 to 2.26, P= 0.036) and research methods taught in a student selected component (OR 1.75, 1.21 to 2.54, P=0.003). Nearly one-third of students lacked formal training on undertaking research, and half of students lacked formal audit training and opportunities to

  10. Calculating the Unit Cost Factors for Decommissioning Cost Estimation of the Nuclear Research Reactor

    International Nuclear Information System (INIS)

    Jeong, Kwan Seong; Lee, Dong Gyu; Jung, Chong Hun; Lee, Kune Woo

    2006-01-01

    The estimated decommissioning cost of nuclear research reactor is calculated by applying a unit cost factor-based engineering cost calculation method on which classification of decommissioning works fitted with the features and specifications of decommissioning objects and establishment of composition factors are based. Decommissioning cost of nuclear research reactor is composed of labor cost, equipment and materials cost. Labor cost of decommissioning costs in decommissioning works are calculated on the basis of working time consumed in decommissioning objects. In this paper, the unit cost factors and work difficulty factors which are needed to calculate the labor cost in estimating decommissioning cost of nuclear research reactor are derived and figured out.

  11. Analysis of the intellectual structure of human space exploration research using a bibliometric approach: Focus on human related factors

    Science.gov (United States)

    Lee, Tai Sik; Lee, Yoon-Sun; Lee, Jaeho; Chang, Byung Chul

    2018-02-01

    Human space exploration (HSE) is an interdisciplinary field composed of a range of subjects that have developed dramatically over the last few decades. This paper investigates the intellectual structure of HSE research with a focus on human related factors. A bibliometric approach with quantitative analytical techniques is applied to study the development and growth of the research. This study retrieves 1921 papers on HSE related to human factors from the year 1990 to the year 2016 from Web of Science and constructs a critical citation network composed of 336 papers. Edge-betweenness-based clustering is used to classify the citation network into twelve distinct research clusters based on four research themes: "biological risks from space radiation," "health and performance during long-duration spaceflight," "program and in-situ resources for HSE missions," and "habitat and life support systems in the space environment." These research themes are also similar to the classification results of a co-occurrence analysis on keywords for a total of 1921 papers. Papers with high centrality scores are identified as important papers in terms of knowledge flow. Moreover, the intermediary role of papers in exchanging knowledge between HSE sub-areas is identified using brokerage analysis. The key-route main path highlights the theoretical development trajectories. Due to the recent dramatic increase in investment by international governments and the private sector, the theoretical development trajectories of key research themes have been expanding from furthering scientific and technical knowledge to include various social and economic issues, thus encouraging massive public participation. This study contributes to an understanding of research trends and popular issues in the field of HSE by introducing a powerful way of determining major research themes and development trajectories. This study will help researchers seek the underlying knowledge diffusion flow from multifaceted

  12. Overview of recent endeavors on personal aerial vehicles: A focus on the US and Europe led research activities

    Science.gov (United States)

    Liu, Yaolong; Kreimeier, Michael; Stumpf, Eike; Zhou, Yaoming; Liu, Hu

    2017-05-01

    Personal aerial vehicles, an innovative transport mode to bridge the niche between scheduled airliners and ground transport, are seen by aviation researchers and engineers as a solution to provide fast urban on-demand mobility. This paper reviews recent research efforts on the personal aerial vehicle (PAV), with a focus on the US and Europe led research activities. As an extension of the programmatic level overview, several enabling technologies, such as vertical/short take-off and landing (V/STOL), automation, distributed electric propulsion, which might promote the deployment of PAVs, are introduced and discussed. Despite the dramatic innovation in PAV concept development and related technologies, some challenging issues remain, especially safety, infrastructure and public acceptance. As such, further efforts by many stakeholders are required to enable the real implementation and application of PAVs.

  13. Estimating drought induced tree mortality in the Amazon rainforest: A simulation study with a focus on plant hydraulic processes

    Science.gov (United States)

    Papastefanou, P.; Fleischer, K.; Hickler, T.; Grams, T.; Lapola, D.; Quesada, C. A.; Zang, C.; Rammig, A.

    2017-12-01

    The Amazon basin was recently hit by severe drought events that were unprecedented in their severity and spatial extent, e.g. during 2005, 2010 and 2015/2016. Significant amounts of biomass were lost, turning large parts of the rainforest from a carbon sink into a carbon source. It is assumed that drought-induced tree mortality from hydraulic failure played an important role during these events and may become more frequent in the Amazon region in the future. Many state-of-the-art dynamic vegetation models do not include plant hydraulic processes and fail to reproduce observed rainforest responses to drought events, such as e.g. increased tree mortality. We address this research gap by developing a simple plant-hydraulic module for the dynamic vegetation model LPJ-GUESS. This plant-hydraulic module uses leaf water potential and cavitation as baseline processes to simulate tree mortality under drought stress. Furthermore, we introduce different plant strategies in the model, which describe e.g. differences in the stomatal regulation under drought stress. To parameterize and evaluate our hydraulic module, we use a set of available observational data from the Amazon region. We apply our model to the Amazon Basin and highlight similarities and differences across other measured and predicted drought responses, e.g. extrapolated observations and data derived from satellite measurements. Our results highlight the importance of including plant hydraulic processes in dynamic vegetation models to correctly predict vegetation dynamics under drought stress and show major differences on the vegetation dynamics depending on the selected plant strategies. We also identify gaps in process understanding of the triggering factors, the extent and the consequences of drought responses that hampers our ability to predict potential impact of future drought events on the Amazon rainforest.

  14. Research on pinches driven by Speed-2 generator: Hard X-ray and neutron emission in plasma focus configuration

    Energy Technology Data Exchange (ETDEWEB)

    Soto, L.; Moreno, J.; Silva, P.; Sylvester, G.; Zambra, M.; Pavez, C. [Comision Chilena de Energia Nuclear, Santiago (Chile); Pavez, C. [Universidad de Concepcion (Chile); Raspa, V. [Buenos Aires Univ., PLADEMA, CONICET and INFIP (Argentina); Castillo, F. [Insitituto de Ciencias Nucleares, UNAM (Mexico); Kies, W. [Heinrich-Heine-Univ., Dusseldorf (Germany)

    2004-07-01

    Speed-2 is a generator based on Marx technology and was designed in the University of Dusseldorf. Speed-2 consists on 40 +/- Marx modules connected in parallel (4.1 {mu}F equivalent Marx generator capacity, 300 kV, 4 MA in short circuit, 187 kJ, 400 ns rise time, dI/dt {approx} 10{sup 13} A/s). Currently Speed-2 is operating at CCHEN (Chilean nuclear energy commission), being the most powerful and energetic device for dense transient plasma in the Southern Hemisphere. Most of the previous works developed in Speed-2 at Dusseldorf were done in a plasma focus configuration for soft X-ray emission and the neutron emission from Speed-2 was not completely studied. The research program at CCHEN considers experiments in different pinch configurations (plasma focus, gas puffed plasma focus, gas embedded Z-pinch, wire arrays) at current of hundred of kilo- to mega-amperes, using the Speed-2 generator. The Chilean operation has begun implementing and developing diagnostics in a conventional plasma focus configuration operating in deuterium in order to characterize the neutron emission and the hard X-ray production. Silver activation counters, plastics CR39 and scintillator-photomultiplier detectors are used to characterize the neutron emission. Images of metallic plates with different thickness are obtained on commercial radiographic film, Agfa Curix ST-G2, in order to characterize an effective energy of the hard X-ray outside of the discharge. (authors)

  15. Cascadia GeoSciences: Community-Based Earth Science Research Focused on Geologic Hazard Assessment and Environmental Restoration.

    Science.gov (United States)

    Williams, T. B.; Patton, J. R.; Leroy, T. H.

    2007-12-01

    Cascadia GeoSciences (CG) is a new non-profit membership governed corporation whose main objectives are to conduct and promote interdisciplinary community based earth science research. The primary focus of CG is on geologic hazard assessment and environmental restoration in the Western U.S. The primary geographic region of interest is Humboldt Bay, NW California, within the southern Cascadia subduction zone (SCSZ). This region is the on-land portion of the accretionary prism to the SCSZ, a unique and exciting setting with numerous hazards in an active, dynamic geologic environment. Humboldt Bay is also a region rich in history. Timber harvesting has been occurring in California's coastal forestlands for approximately 150 years. Timber products transported with ships and railroads from Mendocino and Humboldt Counties helped rebuild San Francisco after the 1906 earthquake. Historic land-use of this type now commonly requires the services of geologists, engineers, and biologists to restore road networks as well as provide safe fish passage. While Humboldt Bay is a focus of some of our individual research goals, we welcome regional scientists to utilize CG to support its mission while achieving their goals. An important function of CG is to provide student opportunities in field research. One of the primary charitable contributions of the organization is a student grant competition. Funds for the student grant will come from member fees and contributions, as well as a percent of all grants awarded to CG. A panel will review and select the student research proposal annually. In addition to supporting student research financially, professional members of CG will donate their time as mentors to the student researchers, promoting a student mentor program. The Humboldt Bay region is well suited to support annual student research. Thorough research like this will help unravel some of the mysteries of regional earthquake-induced land-level changes, as well as possible fault

  16. A Teaching Strategy with a Focus on Argumentation to Improve Undergraduate Students’ Ability to Read Research Articles

    Science.gov (United States)

    Lacum, Edwin B. Van; Goedhart, Martin J.

    2014-01-01

    The aim of this study is to evaluate a teaching strategy designed to teach first-year undergraduate life sciences students at a research university how to learn to read authentic research articles. Our approach—based on the work done in the field of genre analysis and argumentation theory—means that we teach students to read research articles by teaching them which rhetorical moves occur in research articles and how they can identify these. Because research articles are persuasive by their very nature, we focused on the rhetorical moves that play an important role in authors’ arguments. We designed a teaching strategy using cognitive apprenticeship as the pedagogical approach. It was implemented in a first-year compulsory course in the life sciences undergraduate program. Comparison of the results of a pretest with those of the posttest showed that students’ ability to identify these moves had improved. Moreover, students themselves had also perceived that their ability to read and understand a research article had increased. The students’ evaluations demonstrated that they appreciated the pedagogical approach used and experienced the assignments as useful. On the basis of our results, we concluded that students had taken a first step toward becoming expert readers. PMID:26086657

  17. Grupo focal em pesquisa qualitativa sobre leitura com jovens Focus groups in qualitative research about reading with youths

    Directory of Open Access Journals (Sweden)

    Márcia Cabral da Silva

    2012-03-01

    Full Text Available Este artigo trata de uma experiência em pesquisa qualitativa sobre leitura com jovens na área da Educação, utilizando-se como método de coleta de dados o grupo focal. O método foi descrito e analisado à luz da abordagem sócio-histórica da linguagem. Além disso, o texto discute os desafios e as reflexões éticas em relação à utilização do método.This paper describes a qualitative research about reading with youths in the educational fields using focus groups methodology. The concept of focus groups was described and analyzed in the light of the social historical perspective of language. Furthermore, this text discusses the challenges and the ethical concerns regarding this methodology.

  18. On researching erosion-corrosion wear in pipelines: the rate and residual lifetime estimation

    International Nuclear Information System (INIS)

    Baranenko, V.I.; Yanchenko, Yu.A.; Gulina, O.M.; Dokukin, D.A.

    2010-01-01

    To base the normative document on calculation of pipelines erosive-corrosive wear (ECW) rate and residual lifetime this research of ECW regularities for pearlitic steel NPP pipelines was performed. The estimates of control data treatment statistical procedures efficiency were presented. The influence of the scheme of piping control on the ECW rate and residual lifetime estimation results was demonstrated. The simplified scheme is valid only in case of complete information. It's usage under data uncertainties leads to essential residual lifetime overstating [ru

  19. Action research in rehabilitation with chronic stroke recovery: A case report with a focus on neural plasticity.

    Science.gov (United States)

    Pedersen, Malene; Bundgaard, Tina H; Zeeman, Peter; Jørgensen, Jørgen R; Sørensen, Peter M B; Berro, Hamza M; Larsson, Bodil W

    2016-06-27

    Chronic stroke patients are primarily referred to general rehabilitation, rather than to specific neurorehabilitation. Currently, there are no Danish clinical guidelines for chronic stroke, but recent research in neuroplasticity has contributed to possible rehabilitation interventions for these patients. The purpose of this project is to describe the use of a specialized neuroplastic approach in combination with an already existing training program. The project is designed as an action research project concerning four participants with chronic stroke. Through ten intervention, a neuroplastic focus has been added to their group training program including daily home training. Participants were tested before and after the intervention with MAS, DGI, 6MWT, SSQLS. All four participants improved their functional levels and their quality of life following the intervention. This report indicates that a specific neuroplastic focus in combination with action research has an impact on the participants with chronic stroke. However, there is still no clarity regarding what type of rehabilitation methods can be considered the most efficacious in promoting neuroplasticity. This case report serves as a pilot project for further studies of how to implement neuroplasticity in physical therapy.

  20. How to Research People's First Impressions of Websites? Eye-Tracking as a Usability Inspection Method and Online Focus Group Research

    Science.gov (United States)

    Herendy, Csilla

    The visual surface of the Hungarian governmental portal - magyarorszag.hu - was inspected in 2007 with two different inspection methods: Eye tacking research and Online focus group research. Both methods help to understand and to chart not only the usability of different websites but also the affective imp ressions associated with the websites. In this study, an Experimental and a Control-group were tested to assess the usability of the site and the emotional re actions to it. The results reveal that the Hungarian government website is too complicated, dull and difficult to apprehend at a glance.

  1. Perceptions of Faculty toward Integrating Technology in Undergraduate Higher Education Traditional Classrooms at Research-Focused Regional Universities in South Texas

    Science.gov (United States)

    Shipman, Cheri Deann

    2017-01-01

    This qualitative study examined the perceptions of faculty members who use technology in undergraduate higher education traditional classrooms in research-focused regional universities in South Texas. Faculty members at research-focused regional universities are expected to divide time judiciously into three major areas: research, service, and…

  2. Economic terms and beyond how researchers in specialised varieties of English can benefit from focusing on terms

    CERN Document Server

    Resche, Catherine

    2013-01-01

    This book, which is aimed at researchers in specialised varieties of English, provides an illustration of how linguists can use terms, i.e. the expression of concepts in specialised fields, as entry points to explore any specialised domain, whether academic or professional, and to get acquainted with its history, its culture, and the evolution of the ideas that have nurtured it. Choosing the field of economics as an example, the author approaches terms from a diachronic, descriptive and contextual perspective, focusing on neonyms, metaphorical, ambiguous or indeterminate terms, as well as inte

  3. PROVISION OF RESEARCH SUPPORT SERVICES TO ODL LEARNERS BY TUTORS: A Focus on the Zimbabwe Open University’s Bachelor of Education (Educational Management Research Students’ Supervision Experiences

    Directory of Open Access Journals (Sweden)

    Tichaona MAPOLISA

    2012-04-01

    Full Text Available The study examined the ODL learners’ perceptions of the quality of provision of research support services to the ODL learners by tutors. It focused on the Zimbabwe Open University’s (ZOU Bachelor of Education (Educational Management research students’ experiences. It was a qualitative multiple case study of four of the 10 Regional Centres of the ZOU. It purposively sampled 40 out of 160 research participants because they possessed desirable research characteristics for this study. The study was deemed significant in influencing tutors and policy makers to consider their research students’ supervision experiences as a basis for improving the quality of services for future research supervision practices and research projects. The study was guided by a two fold theory namely, thee Facilitation Theory (Nyawaranda, 2005 and the Nurturing Theory (Anderson, Pay and Mac Laughlin, 2006. Both theories advocate for the need of the supervisors to give their students a big heart. In terms of research supervision services offered by tutors the study indicated the time students were offered to meet research supervisors, prompt returns of marked work, and tutor student motivation and counselling as key services. In connection with the joys about research supervision, the students highly regarded: the manner in which tutors motivated them, tutors guidance in choosing research topic, tutor mentorship during research supervision and provision of workshops to polish up their research skills. In line with the challenges to the provision of research support services, three categories of challenges emerged. First, student-related challenges included lack of time, lack of money, lack of library facilities, lack of motivation and commitment to do research, lack of adequate theory in the area being researched on and family problems. Second, supervisor-related challenges included: too little direction, too little practical help given, too few meeting with students

  4. Focused Ethnography

    Directory of Open Access Journals (Sweden)

    Hubert Knoblauch

    2005-09-01

    Full Text Available In this paper I focus on a distinctive kind of sociological ethnography which is particularly, though not exclusively, adopted in applied research. It has been proposed that this branch of ethno­graphy be referred to as focused ethnography. Focused ethnography shall be delineated within the context of other common conceptions of what may be called conventional ethnography. However, rather than being opposed to it, focused ethno­graphy is rather complementary to conventional ethnography, particularly in fields that are charac­teristic of socially and functionally differentiated contemporary society. The paper outlines the back­ground as well as the major methodological features of focused ethnography, such as short-term field visits, data intensity and time intensity, so as to provide a background for future studies in this area. URN: urn:nbn:de:0114-fqs0503440

  5. Patients’ and caregivers’ needs, experiences, preferences and research priorities in spiritual care: A focus group study across nine countries

    Science.gov (United States)

    Selman, Lucy Ellen; Brighton, Lisa Jane; Sinclair, Shane; Karvinen, Ikali; Egan, Richard; Speck, Peter; Powell, Richard A; Deskur-Smielecka, Ewa; Glajchen, Myra; Adler, Shelly; Puchalski, Christina; Hunter, Joy; Gikaara, Nancy; Hope, Jonathon

    2017-01-01

    Background: Spiritual distress is prevalent in advanced disease, but often neglected, resulting in unnecessary suffering. Evidence to inform spiritual care practices in palliative care is limited. Aim: To explore spiritual care needs, experiences, preferences and research priorities in an international sample of patients with life-limiting disease and family caregivers. Design: Focus group study. Setting/participants: Separate patient and caregiver focus groups were conducted at 11 sites in South Africa, Kenya, South Korea, the United States, Canada, the United Kingdom, Belgium, Finland and Poland. Discussions were transcribed, translated into English and analysed thematically. Results: A total of 74 patients participated: median age 62 years; 53 had cancer; 48 were women. In total, 71 caregivers participated: median age 61 years; 56 were women. Two-thirds of participants were Christian. Five themes are described: patients’ and caregivers’ spiritual concerns, understanding of spirituality and its role in illness, views and experiences of spiritual care, preferences regarding spiritual care, and research priorities. Participants reported wide-ranging spiritual concerns spanning existential, psychological, religious and social domains. Spirituality supported coping, but could also result in framing illness as punishment. Participants emphasised the need for staff competence in spiritual care. Spiritual care was reportedly lacking, primarily due to staff members’ de-prioritisation and lack of time. Patients’ research priorities included understanding the qualities of human connectedness and fostering these skills in staff. Caregivers’ priorities included staff training, assessment, studying impact, and caregiver’s spiritual care needs. Conclusion: To meet patient and caregiver preferences, healthcare providers should be able to address their spiritual concerns. Findings should inform patient- and caregiver-centred spiritual care provision, education and

  6. A Teaching Strategy with a Focus on Argumentation to Improve Undergraduate Students' Ability to Read Research Articles.

    Science.gov (United States)

    Van Lacum, Edwin B; Ossevoort, Miriam A; Goedhart, Martin J

    2014-01-01

    The aim of this study is to evaluate a teaching strategy designed to teach first-year undergraduate life sciences students at a research university how to learn to read authentic research articles. Our approach-based on the work done in the field of genre analysis and argumentation theory-means that we teach students to read research articles by teaching them which rhetorical moves occur in research articles and how they can identify these. Because research articles are persuasive by their very nature, we focused on the rhetorical moves that play an important role in authors' arguments. We designed a teaching strategy using cognitive apprenticeship as the pedagogical approach. It was implemented in a first-year compulsory course in the life sciences undergraduate program. Comparison of the results of a pretest with those of the posttest showed that students' ability to identify these moves had improved. Moreover, students themselves had also perceived that their ability to read and understand a research article had increased. The students' evaluations demonstrated that they appreciated the pedagogical approach used and experienced the assignments as useful. On the basis of our results, we concluded that students had taken a first step toward becoming expert readers. © 2014 E. B. Van Lacum et al. CBE—Life Sciences Education © 2014 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  7. Experiments, conceptual design, preliminary cost estimates and schedules for an underground research facility

    International Nuclear Information System (INIS)

    Korbin, G.; Wollenberg, H.; Wilson, C.; Strisower, B.; Chan, T.; Wedge, D.

    1981-09-01

    Plans for an underground research facility are presented, incorporating techniques to assess the hydrological and thermomechanical response of a rock mass to the introduction and long-term isolation of radioactive waste, and to assess the effects of excavation on the hydrologic integrity of a repository and its subsequent backfill, plugging, and sealing. The project is designed to utilize existing mine or civil works for access to experimental areas and is estimated to last 8 years at a total cost for contruction and operation of $39.0 million (1981 dollars). Performing the same experiments in an existing underground research facility would reduce the duration to 7-1/2 years and cost $27.7 million as a lower-bound estimate. These preliminary plans and estimates should be revised after specific sites are identified which would accommodate the facility

  8. Enhancing Research Ethics Review Systems in Egypt: The Focus of an International Training Program Informed by an Ecological Developmental Approach to Enhancing Research Ethics Capacity.

    Science.gov (United States)

    Edwards, Hillary Anne; Hifnawy, Tamer; Silverman, Henry

    2015-12-01

    Recently, training programs in research ethics have been established to enhance individual and institutional capacity in research ethics in the developing world. However, commentators have expressed concern that the efforts of these training programs have placed 'too great an emphasis on guidelines and research ethics review', which will have limited effect on ensuring ethical conduct in research. What is needed instead is a culture of ethical conduct supported by national and institutional commitment to ethical practices that are reinforced by upstream enabling conditions (strong civil society, public accountability, and trust in basic transactional processes), which are in turn influenced by developmental conditions (basic freedoms of political freedoms, economic facilities, social opportunities, transparency guarantees, and protective security). Examining this more inclusive understanding of the determinants of ethical conduct enhances at once both an appreciation of the limitations of current efforts of training programs in research ethics and an understanding of what additional training elements are needed to enable trainees to facilitate national and institutional policy changes that enhance research practices. We apply this developmental model to a training program focused in Egypt to describe examples of such additional training activities. © 2014 John Wiley & Sons Ltd.

  9. Using a creativity-focused science program to foster general creativity in young children: A teacher action research study

    Science.gov (United States)

    Gomes, Joan Julieanne Mariani

    The importance of thinking and problem-solving skills, and the ability to integrate and analyze information has been recognized and yet may be lacking in schools. Creativity is inherently linked to problem finding, problem solving, and divergent thinking (Arieti, 1976; Csikszentmihalyi, 1990; Milgram, 1990). The importance of early childhood education and its role in the formation of young minds has been recognized (Caine & Caine, 1991; Montessori, 1967a, 1967b; Piaget, 1970). Early childhood education also impacts creativity (Gardner, 1999). The features of brain-based learning (Caine & Caine, 1991; Jensen, 1998; Sousa, 2001; Wolfe, 2001) have a clear connection to nurturing the creative potential in students. Intrinsic motivation and emotions affect student learning and creativity as well (Hennessey & Amabile, 1987). The purpose of this study was to discern if a creativity-focused science curriculum for the kindergarteners at a Montessori early learning center could increase creativity in students. This action research study included observations of the students in two classrooms, one using the creativity-focused science curriculum, and the other using the existing curriculum. The data collected for this interpretive study included interviews with the students, surveys and interviews with their parents and teachers, teacher observations, and the administration of Torrance's (1981) Thinking Creatively in Action and Movement (TCAM) test. The interpretation of the data indicated that the enhanced science curriculum played a role in enhancing the creativity of the children in the creativity-focused group. The results of the TCAM (Torrance, 1981) showed a significant increase in scores for the children in the creativity-focused group. The qualitative data revealed a heightened interest in science and the observation of creative traits, processes, and products in the creativity-focused group children. The implications of this study included the need for meaningful

  10. Future Estimation of Convenience Living Facilities Withdrawal due to Population Decline all Over Japan from 2010 TO 2040 - Focus on Supermarkets, Convenience Stores and Drugstores

    Science.gov (United States)

    Nishimoto, Yuka; Akiyama, Yuki; Shibasaki, Ryosuke

    2016-06-01

    Population explosion is considered to be one of the most crucial problems in the world. However, in Japan, the opposite problem: population decline has become serious now. Japanese population is estimated to decrease by twenty millions in 2040. This negative situation will cause to increase areas where many residents cannot make a daily living all over Japan because many convenience living facilities such as supermarkets, convenience stores and drugstores will be difficult to maintain their market area population due to future population decline. In our research, we used point data of convenience living facilities developed by address geocoding of digital telephone directory and point data of future population projection developed by distribution of Japanese official population projection data proportionally among the building volume of digital residential map, which can monitor building volumes all over Japan. In conclusion, we estimated that various convenience living facilities in Japan will shrink and close by population decline in near future. In particular, it is cleared that approximately 14.7% of supermarkets will be possible to withdraw all over Japan by 2040. In addition, it is cleared that over 40% of supermarkets in some countryside prefectures will be possible to withdraw by 2040. Thus, we estimated future distributions of convenience living facilities that cannot maintain their market area population due to future population decline. Moreover, we estimated the number of people that they will become inconvenience in buying fresh foods.

  11. FUTURE ESTIMATION OF CONVENIENCE LIVING FACILITIES WITHDRAWAL DUE TO POPULATION DECLINE ALL OVER JAPAN FROM 2010 TO 2040 - FOCUS ON SUPERMARKETS, CONVENIENCE STORES AND DRUGSTORES

    Directory of Open Access Journals (Sweden)

    Y. Nishimoto

    2016-06-01

    Full Text Available Population explosion is considered to be one of the most crucial problems in the world. However, in Japan, the opposite problem: population decline has become serious now. Japanese population is estimated to decrease by twenty millions in 2040. This negative situation will cause to increase areas where many residents cannot make a daily living all over Japan because many convenience living facilities such as supermarkets, convenience stores and drugstores will be difficult to maintain their market area population due to future population decline. In our research, we used point data of convenience living facilities developed by address geocoding of digital telephone directory and point data of future population projection developed by distribution of Japanese official population projection data proportionally among the building volume of digital residential map, which can monitor building volumes all over Japan. In conclusion, we estimated that various convenience living facilities in Japan will shrink and close by population decline in near future. In particular, it is cleared that approximately 14.7% of supermarkets will be possible to withdraw all over Japan by 2040. In addition, it is cleared that over 40% of supermarkets in some countryside prefectures will be possible to withdraw by 2040. Thus, we estimated future distributions of convenience living facilities that cannot maintain their market area population due to future population decline. Moreover, we estimated the number of people that they will become inconvenience in buying fresh foods.

  12. Future PMPs Estimation in Korea under AR5 RCP 8.5 Climate Change Scenario: Focus on Dew Point Temperature Change

    Science.gov (United States)

    Okjeong, Lee; Sangdan, Kim

    2016-04-01

    According to future climate change scenarios, future temperature is expected to increase gradually. Therefore, it is necessary to reflect the effects of these climate changes to predict Probable Maximum Precipitations (PMPs). In this presentation, PMPs will be estimated with future dew point temperature change. After selecting 174 major storm events from 1981 to 2005, new PMPs will be proposed with respect to storm areas (25, 100, 225, 400, 900, 2,025, 4,900, 10,000 and 19,600 km2) and storm durations (1, 2, 4, 6, 8, 12, 18, 24, 48 and 72 hours) using the Korea hydro-meteorological method. Also, orographic transposition factor will be applied in place of the conventional terrain impact factor which has been used in previous Korean PMPs estimation reports. After estimating dew point temperature using future temperature and representative humidity information under the Korea Meteorological Administration AR5 RCP 8.5, changes in the PMPs under dew point temperature change will be investigated by comparison with present and future PMPs. This research was supported by a grant(14AWMP-B082564-01) from Advanced Water Management Research Program funded by Ministry of Land, Infrastructure and Transport of Korean government.

  13. Editorial: Illuminating the dark matter of developmental neuropsychiatric genetics - strategic focus for future research in child psychology and psychiatry.

    Science.gov (United States)

    Lesch, Klaus-Peter

    2014-03-01

    Research on genetic factors influencing cognitive and behavioural traits or which are central to the aetiology of neuropsychiatric diseases has been complicated by a furtive discrepancy between high heritability estimates and a scarcity of replicable gene-disorder associations. This 'missing heritability' has been either euphemised as the 'dark matter' of gene-trait association or aggravated as the 'looming crisis in behavioural genetics'. Nevertheless, in recognising the importance of this topic for our understanding of child psychiatric conditions and highlighting its commitment to the field, the Journal of Child Psychology and Psychiatry (JCPP) has for the first time appointed an editor with special responsibility for molecular (epi)genetics. © 2014 The Authors. Journal of Child Psychology and Psychiatry. © 2014 Association for Child and Adolescent Mental Health.

  14. [Research Progress of Vitreous Humor Detection Technique on Estimation of Postmortem Interval].

    Science.gov (United States)

    Duan, W C; Lan, L M; Guo, Y D; Zha, L; Yan, J; Ding, Y J; Cai, J F

    2018-02-01

    Estimation of postmortem interval (PMI) plays a crucial role in forensic study and identification work. Because of the unique anatomy location, vitreous humor is considered to be used for estima- ting PMI, which has aroused interest among scholars, and some researches have been carried out. The detection techniques of vitreous humor are constantly developed and improved which have been gradually applied in forensic science, meanwhile, the study of PMI estimation using vitreous humor is updated rapidly. This paper reviews various techniques and instruments applied to vitreous humor detection, such as ion selective electrode, capillary ion analysis, spectroscopy, chromatography, nano-sensing technology, automatic biochemical analyser, flow cytometer, etc., as well as the related research progress on PMI estimation in recent years. In order to provide a research direction for scholars and promote a more accurate and efficient application in PMI estimation by vitreous humor analysis, some inner problems are also analysed in this paper. Copyright© by the Editorial Department of Journal of Forensic Medicine.

  15. How do scientists perceive the current publication culture? A qualitative focus group interview study among Dutch biomedical researchers.

    Science.gov (United States)

    Tijdink, J K; Schipper, K; Bouter, L M; Maclaine Pont, P; de Jonge, J; Smulders, Y M

    2016-02-17

    To investigate the biomedical scientist's perception of the prevailing publication culture. Qualitative focus group interview study. Four university medical centres in the Netherlands. Three randomly selected groups of biomedical scientists (PhD, postdoctoral staff members and full professors). Main themes for discussion were selected by participants. Frequently perceived detrimental effects of contemporary publication culture were the strong focus on citation measures (like the Journal Impact Factor and the H-index), gift and ghost authorships and the order of authors, the peer review process, competition, the funding system and publication bias. These themes were generally associated with detrimental and undesirable effects on publication practices and on the validity of reported results. Furthermore, senior scientists tended to display a more cynical perception of the publication culture than their junior colleagues. However, even among the PhD students and the postdoctoral fellows, the sentiment was quite negative. Positive perceptions of specific features of contemporary scientific and publication culture were rare. Our findings suggest that the current publication culture leads to negative sentiments, counterproductive stress levels and, most importantly, to questionable research practices among junior and senior biomedical scientists. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  16. A Study on Environmental Research Trends Using Text-Mining Method - Focus on Spatial information and ICT -

    Science.gov (United States)

    Lee, M. J.; Oh, K. Y.; Joung-ho, L.

    2016-12-01

    Recently there are many research about analysing the interaction between entities by text-mining analysis in various fields. In this paper, we aimed to quantitatively analyse research-trends in the area of environmental research relating either spatial information or ICT (Information and Communications Technology) by Text-mining analysis. To do this, we applied low-dimensional embedding method, clustering analysis, and association rule to find meaningful associative patterns of key words frequently appeared in the articles. As the authors suppose that KCI (Korea Citation Index) articles reflect academic demands, total 1228 KCI articles that have been published from 1996 to 2015 were reviewed and analysed by Text-mining method. First, we derived KCI articles from NDSL(National Discovery for Science Leaders) site. And then we pre-processed their key-words elected from abstract and then classified those in separable sectors. We investigated the appearance rates and association rule of key-words for articles in the two fields: spatial-information and ICT. In order to detect historic trends, analysis was conducted separately for the four periods: 1996-2000, 2001-2005, 2006-2010, 2011-2015. These analysis were conducted with the usage of R-software. As a result, we conformed that environmental research relating spatial information mainly focused upon such fields as `GIS(35%)', `Remote-Sensing(25%)', `environmental theme map(15.7%)'. Next, `ICT technology(23.6%)', `ICT service(5.4%)', `mobile(24%)', `big data(10%)', `AI(7%)' are primarily emerging from environmental research relating ICT. Thus, from the analysis results, this paper asserts that research trends and academic progresses are well-structured to review recent spatial information and ICT technology and the outcomes of the analysis can be an adequate guidelines to establish environment policies and strategies. KEY WORDS: Big data, Test-mining, Environmental research, Spatial-information, ICT Acknowledgements: The

  17. Nonparametric estimation for censored mixture data with application to the Cooperative Huntington's Observational Research Trial.

    Science.gov (United States)

    Wang, Yuanjia; Garcia, Tanya P; Ma, Yanyuan

    2012-01-01

    This work presents methods for estimating genotype-specific distributions from genetic epidemiology studies where the event times are subject to right censoring, the genotypes are not directly observed, and the data arise from a mixture of scientifically meaningful subpopulations. Examples of such studies include kin-cohort studies and quantitative trait locus (QTL) studies. Current methods for analyzing censored mixture data include two types of nonparametric maximum likelihood estimators (NPMLEs) which do not make parametric assumptions on the genotype-specific density functions. Although both NPMLEs are commonly used, we show that one is inefficient and the other inconsistent. To overcome these deficiencies, we propose three classes of consistent nonparametric estimators which do not assume parametric density models and are easy to implement. They are based on the inverse probability weighting (IPW), augmented IPW (AIPW), and nonparametric imputation (IMP). The AIPW achieves the efficiency bound without additional modeling assumptions. Extensive simulation experiments demonstrate satisfactory performance of these estimators even when the data are heavily censored. We apply these estimators to the Cooperative Huntington's Observational Research Trial (COHORT), and provide age-specific estimates of the effect of mutation in the Huntington gene on mortality using a sample of family members. The close approximation of the estimated non-carrier survival rates to that of the U.S. population indicates small ascertainment bias in the COHORT family sample. Our analyses underscore an elevated risk of death in Huntington gene mutation carriers compared to non-carriers for a wide age range, and suggest that the mutation equally affects survival rates in both genders. The estimated survival rates are useful in genetic counseling for providing guidelines on interpreting the risk of death associated with a positive genetic testing, and in facilitating future subjects at risk

  18. Inclusion as a focus of employment-related research in intellectual disability from 2000 to 2010: a scoping review.

    Science.gov (United States)

    Lysaght, Rosemary; Cobigo, Virginie; Hamilton, Kate

    2012-01-01

    This paper presents the results of a scoping review of the research literature on community-based employment for individuals with intellectual disabilities from 2000 to 2010. The review examined the variables studied in each paper, and considered the degree to which elements of social inclusion were addressed. The search strategy identified a total of 245 articles, the total pool of which was reduced to 42 following abstract and text review. Two researchers reviewed the final set of articles and extracted information relevant to the study goals. Independent and dependent measures used in the studies were categorized relative to a conceptual model of social inclusion. The frequency with which each aspect of inclusion was addressed in the studies was totalled, and the resulting pattern analyzed qualitatively. The analysis revealed that the majority of papers identified the work role achieved (i.e. employment and pay rates, job titles) as the primary construct of interest, while fewer than 5 articles focused on central aspects of inclusion, such as sense of belonging, reciprocity, and need fulfillment. This study profiles the evidence base relative to inclusive employment for people with intellectual disabilities. The lack of evidence on the degree to which social inclusion is being achieved through community-based employment highlights a critical area requiring attention.

  19. [Measurement and estimation methods and research progress of snow evaporation in forests].

    Science.gov (United States)

    Li, Hui-Dong; Guan, De-Xin; Jin, Chang-Jie; Wang, An-Zhi; Yuan, Feng-Hui; Wu, Jia-Bing

    2013-12-01

    Accurate measurement and estimation of snow evaporation (sublimation) in forests is one of the important issues to the understanding of snow surface energy and water balance, and it is also an essential part of regional hydrological and climate models. This paper summarized the measurement and estimation methods of snow evaporation in forests, and made a comprehensive applicability evaluation, including mass-balance methods (snow water equivalent method, comparative measurements of snowfall and through-snowfall, snow evaporation pan, lysimeter, weighing of cut tree, weighing interception on crown, and gamma-ray attenuation technique) and micrometeorological methods (Bowen-ratio energy-balance method, Penman combination equation, aerodynamics method, surface temperature technique and eddy covariance method). Also this paper reviewed the progress of snow evaporation in different forests and its influencal factors. At last, combining the deficiency of past research, an outlook for snow evaporation rearch in forests was presented, hoping to provide a reference for related research in the future.

  20. In vitro psoriasis models with focus on reconstructed skin models as promising tools in psoriasis research.

    Science.gov (United States)

    Desmet, Eline; Ramadhas, Anesh; Lambert, Jo; Van Gele, Mireille

    2017-06-01

    skin or the disease pathology. This work provides a complete overview of the different available in vitro psoriasis models and suggests improvements for future models. Moreover, a focus was given to psoriatic skin equivalent models, as they offer several advantages over the other models, including commercial availability and validity. The potential and reported applicability of these models in psoriasis pre-clinical research is extensively discussed. As such, this work offers a guide to researchers in their choice of pre-clinical psoriasis model depending on their type of research question.

  1. A comparison of methods for calculating population exposure estimates of daily weather for health research

    Directory of Open Access Journals (Sweden)

    Dear Keith BG

    2006-09-01

    Full Text Available Abstract Background To explain the possible effects of exposure to weather conditions on population health outcomes, weather data need to be calculated at a level in space and time that is appropriate for the health data. There are various ways of estimating exposure values from raw data collected at weather stations but the rationale for using one technique rather than another; the significance of the difference in the values obtained; and the effect these have on a research question are factors often not explicitly considered. In this study we compare different techniques for allocating weather data observations to small geographical areas and different options for weighting averages of these observations when calculating estimates of daily precipitation and temperature for Australian Postal Areas. Options that weight observations based on distance from population centroids and population size are more computationally intensive but give estimates that conceptually are more closely related to the experience of the population. Results Options based on values derived from sites internal to postal areas, or from nearest neighbour sites – that is, using proximity polygons around weather stations intersected with postal areas – tended to include fewer stations' observations in their estimates, and missing values were common. Options based on observations from stations within 50 kilometres radius of centroids and weighting of data by distance from centroids gave more complete estimates. Using the geographic centroid of the postal area gave estimates that differed slightly from the population weighted centroids and the population weighted average of sub-unit estimates. Conclusion To calculate daily weather exposure values for analysis of health outcome data for small areas, the use of data from weather stations internal to the area only, or from neighbouring weather stations (allocated by the use of proximity polygons, is too limited. The most

  2. Budget estimates: Fiscal year 1994. Volume 3: Research and program management

    Science.gov (United States)

    1994-01-01

    The research and program management (R&PM) appropriation provides the salaries, other personnel and related costs, and travel support for NASA's civil service workforce. This FY 1994 budget funds costs associated with 23,623 full-time equivalent (FTE) work years. Budget estimates are provided for all NASA centers by categories such as space station and new technology investments, space flight programs, space science, life and microgravity sciences, advanced concepts and technology, center management and operations support, launch services, mission to planet earth, tracking and data programs, aeronautical research and technology, and safety, reliability, and quality assurance.

  3. The unit cost factors and calculation methods for decommissioning - Cost estimation of nuclear research facilities

    International Nuclear Information System (INIS)

    Kwan-Seong Jeong; Dong-Gyu Lee; Chong-Hun Jung; Kune-Woo Lee

    2007-01-01

    Available in abstract form only. Full text of publication follows: The uncertainties of decommissioning costs increase high due to several conditions. Decommissioning cost estimation depends on the complexity of nuclear installations, its site-specific physical and radiological inventories. Therefore, the decommissioning costs of nuclear research facilities must be estimated in accordance with the detailed sub-tasks and resources by the tasks of decommissioning activities. By selecting the classified activities and resources, costs are calculated by the items and then the total costs of all decommissioning activities are reshuffled to match with its usage and objectives. And the decommissioning cost of nuclear research facilities is calculated by applying a unit cost factor method on which classification of decommissioning works fitted with the features and specifications of decommissioning objects and establishment of composition factors are based. Decommissioning costs of nuclear research facilities are composed of labor cost, equipment and materials cost. Of these three categorical costs, the calculation of labor costs are very important because decommissioning activities mainly depend on labor force. Labor costs in decommissioning activities are calculated on the basis of working time consumed in decommissioning objects and works. The working times are figured out of unit cost factors and work difficulty factors. Finally, labor costs are figured out by using these factors as parameters of calculation. The accuracy of decommissioning cost estimation results is much higher compared to the real decommissioning works. (authors)

  4. Focus on focusing

    International Nuclear Information System (INIS)

    Anon.

    1985-01-01

    The discovery and impact of the principle of strong focusing was celebrated at a history Symposium at Stanford on 25 July in the course of the 1985 US Summer School on Particle Accelerators. Burt Richter, Stanford Linac Director, who introduced all the speakers with well chosen reminders about their various contributions related to the theme of the symposium, remarked that it was an appropriate time to be lauding the great contributions of accelerator physicists following the Nobel Prize award to Simon van der Meer for outstanding achievements in accelerator physics

  5. Focus on focusing

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1985-10-15

    The discovery and impact of the principle of strong focusing was celebrated at a history Symposium at Stanford on 25 July in the course of the 1985 US Summer School on Particle Accelerators. Burt Richter, Stanford Linac Director, who introduced all the speakers with well chosen reminders about their various contributions related to the theme of the symposium, remarked that it was an appropriate time to be lauding the great contributions of accelerator physicists following the Nobel Prize award to Simon van der Meer for outstanding achievements in accelerator physics.

  6. Research data management support for large-scale, long-term, interdisciplinary collaborative research centers with a focus on environmental sciences

    Science.gov (United States)

    Curdt, C.; Hoffmeister, D.; Bareth, G.; Lang, U.

    2017-12-01

    Science conducted in collaborative, cross-institutional research projects, requires active sharing of research ideas, data, documents and further information in a well-managed, controlled and structured manner. Thus, it is important to establish corresponding infrastructures and services for the scientists. Regular project meetings and joint field campaigns support the exchange of research ideas. Technical infrastructures facilitate storage, documentation, exchange and re-use of data as results of scientific output. Additionally, also publications, conference contributions, reports, pictures etc. should be managed. Both, knowledge and data sharing is essential to create synergies. Within the coordinated programme `Collaborative Research Center' (CRC), the German Research Foundation offers funding to establish research data management (RDM) infrastructures and services. CRCs are large-scale, interdisciplinary, multi-institutional, long-term (up to 12 years), university-based research institutions (up to 25 sub-projects). These CRCs address complex and scientifically challenging research questions. This poster presents the RDM services and infrastructures that have been established for two CRCs, both focusing on environmental sciences. Since 2007, a RDM support infrastructure and associated services have been set up for the CRC/Transregio 32 (CRC/TR32) `Patterns in Soil-Vegetation-Atmosphere-Systems: Monitoring, Modelling and Data Assimilation' (www.tr32.de). The experiences gained have been used to arrange RDM services for the CRC1211 `Earth - Evolution at the Dry Limit' (www.crc1211.de), funded since 2016. In both projects scientists from various disciplines collect heterogeneous data at field campaigns or by modelling approaches. To manage the scientific output, the TR32DB data repository (www.tr32db.de) has been designed and implemented for the CRC/TR32. This system was transferred and adapted to the CRC1211 needs (www.crc1211db.uni-koeln.de) in 2016. Both

  7. Research focus and trends in nuclear science and technology in Ghana: a bibliometric study based on the INIS database

    International Nuclear Information System (INIS)

    Agyeman, E. A.; Bilson, A.

    2015-01-01

    The peaceful application of atomic energy was introduced into Ghana about fifty years ago. This is the first bibliometric study of nuclear science and technology research publications originating from Ghana and listed in the International Nuclear Information System (INIS) Database. The purpose was to use the simple document counting method to determine the geographical distribution, annual growth and the subject areas of the publications as well as communication channels, key journals and authorship trends. The main findings of the study were that, a greater number of the nuclear science and technology records listed in the Database were published in Ghana (598 or 56.57% against 459 or 43.43% published outside Ghana). There has been a steady growth in the number of publications over the years with the most productive year being 2012. The main focus of research has been in the area of applied life sciences, comprising plant cultivation & breeding, pest & disease control, food protection and preservation, human nutrition and animal husbandry; followed by chemistry; environmental sciences; radiation protection; nuclear reactors; physics; energy; and radiology and nuclear medicine. The area with the least number of publications was safeguards and physical protection. The main channel of communicating research results was peer reviewed journals and a greater number of the journal articles were published in Ghana followed by the United Kingdom, Hungary and the Netherlands. The core journals identified in this study were Journal of Applied Science and Technology; Journal of Radioanalytical and Nuclear Chemistry; Journal of the Ghana Science Association; Radiation Protection Dosimetry; Journal of the Kumasi University of Science and Technology; West African Journal of Applied Ecology; Ghana Journal of Science; Applied Radiation and Isotopes; Annals of Nuclear Energy, IOP Conference Series (Earth and Environmental Science) and Radiation Physics and Chemistry. Eighty percent

  8. Simulation methods to estimate design power: an overview for applied research.

    Science.gov (United States)

    Arnold, Benjamin F; Hogan, Daniel R; Colford, John M; Hubbard, Alan E

    2011-06-20

    Estimating the required sample size and statistical power for a study is an integral part of study design. For standard designs, power equations provide an efficient solution to the problem, but they are unavailable for many complex study designs that arise in practice. For such complex study designs, computer simulation is a useful alternative for estimating study power. Although this approach is well known among statisticians, in our experience many epidemiologists and social scientists are unfamiliar with the technique. This article aims to address this knowledge gap. We review an approach to estimate study power for individual- or cluster-randomized designs using computer simulation. This flexible approach arises naturally from the model used to derive conventional power equations, but extends those methods to accommodate arbitrarily complex designs. The method is universally applicable to a broad range of designs and outcomes, and we present the material in a way that is approachable for quantitative, applied researchers. We illustrate the method using two examples (one simple, one complex) based on sanitation and nutritional interventions to improve child growth. We first show how simulation reproduces conventional power estimates for simple randomized designs over a broad range of sample scenarios to familiarize the reader with the approach. We then demonstrate how to extend the simulation approach to more complex designs. Finally, we discuss extensions to the examples in the article, and provide computer code to efficiently run the example simulations in both R and Stata. Simulation methods offer a flexible option to estimate statistical power for standard and non-traditional study designs and parameters of interest. The approach we have described is universally applicable for evaluating study designs used in epidemiologic and social science research.

  9. Research on an estimation method of DOA for wireless location based on TD-SCDMA

    Science.gov (United States)

    Zhang, Yi; Luo, Yuan; Cheng, Shi-xin

    2004-03-01

    To meet the urgent need of personal communication and hign-speed data services,the standardization and products development for International Mobile Telecommunication-2000 (IMT-2000) have become a hot point in wordwide. The wireless location for mobile terminals has been an important research project. Unlike GPS which is located by 24 artificial satellities, it is based on the base-station of wireless cell network, and the research and development of it are correlative with IMT-2000. While the standard for the third generation mobile telecommunication (3G)-TD-SCDMA, which is proposed by China and the intellective property right of which is possessed by Chinese, is adopted by ITU-T at the first time, the research for wireless location based on TD-SCDMA has theoretic meaning, applied value and marketable foreground. First,the basic principle and method for wireless location, i.e. Direction of Angle(DOA), Time of Arrival(TOA) or Time Difference of Arrival(TDOA), hybridized location(TOA/DOA,TDOA/DOA,TDOA/DOA),etc. is introduced in the paper. So the research of DOA is very important in wireless location. Next, Main estimation methods of DOA for wireless location, i.e. ESPRIT, MUSIC, WSF, Min-norm, etc. are researched in the paper. In the end, the performances of DOA estimation for wireless location based on mobile telecommunication network are analyzed by the research of theory and simulation experiment and the contrast algorithms between and Cramer-Rao Bound. Its research results aren't only propitious to the choice of algorithms for wireless location, but also to the realization of new service of wireless location .

  10. Theoretical Foundations of Research Focused on HIV Prevention Among Substance-Involved Women: A Review of Observational and Intervention Studies.

    Science.gov (United States)

    Auerbach, Judith D; Smith, Laramie R

    2015-06-01

    Although substance use continues to be a significant component of HIV risk among women worldwide, to date, relatively little attention has been paid in research, services, or policy to substance-involved women (SIW). HIV acquisition for SIW stems from transmission risks directly related to substance use and risks associated with sexual activity in which power to negotiate risk and safety are influenced by dynamics of male partnerships, sex work, and criminalization (of both drug use and sex work), among other factors. As such, HIV risk for SIW resides as much in the environment—physical, social, cultural, economic, and political—in which drug use occurs as it does from transmission-related behaviors of individual women. To reduce HIV infections among SIW, it is important to specify the interaction of individual- and environmental-level factors, including, but not limited to those related to women's own substance use, that can and ought to be changed. This involves theorizing about the interplay of gender, substance use, and HIV risk, and incorporating that theoretical understanding into intervention design and evaluation. A review of the published literature focused on HIV prevention among SIW revealed a general lack of theoretical and conceptual foundation specific to the gender-related and environmental drivers of HIV in this population. Greater theoretical linkages to intersectionality and syndemic approaches are recommended to better identify and target relevant mechanisms by which the interplay of gender dynamics and substance use potentiate the likelihood of HIV acquisition and transmission among SIW.

  11. Study of human factors and its basic aspects, focusing the operators of IEA-R1 research reactor

    International Nuclear Information System (INIS)

    Martins, Maria da Penha Sanches; Andrade, Delvonei Alves de

    2008-01-01

    Human factors and situational variables, which ca, when modified, interfere in the actions of operators of nuclear installations is studied. This work is focused in the operators of the IEA-R1 research reactor, which is located in the Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Brazil. The accidents in Nuclear Plants have shown that the most serious have occurred due to human failure. This work also considers the item 5.5.3 of CNEN-NN-3.01 standard - 'Actions must be taken to reduce, as much as possible, the human failures that can lead to accidents or even other events which can originate inadvertent or unintentional expositions in any individual'. The model named 'Behavioral Analysis' is adopted. Relevant factors and aspects of the operators' routine are also considered. It is worth to remind that the performance depends on a series of variables, not only on the individual, but also situational, including in these categories; physical variables, work environment, organizational and the social ones. The subjective factors are also considered, such as: attitude, ability, motivation etc., aiming at a global perspective of the situation, which counts on a set of principles for the behaviour analysis and comprehension. After defining the applicability scenario, mechanisms and corrective actions to contribute with the reduction of failures will be proposed. (author)

  12. Diagnostic systems for the nuclear fusion and plasma research in the PF-24 plasma focus laboratory at the IFJ PAN

    Directory of Open Access Journals (Sweden)

    Marciniak Łukasz

    2016-12-01

    Full Text Available This paper presents a set of diagnostics dedicated to PF-24 - new medium size - plasma focus (PF device built and operated at the Institute of Nuclear Physics Polish Academy of Sciences (IFJ PAN. The PF-24 can operate at energy level up to 93 kJ and charging voltage up to 40 kV. Each condenser is connected with a specially designed spark gap with a very small jitter, which ensures a high effi ciency and a low current rise time. The working parameters of PF-24 generator make it a suitable tool for testing new detection systems to be used in fusion research. Four types of such detection systems are presented in this article: three diagnostic systems used to measure electric quantities (Rogowski coil, magnetic probe, capacitance probe, neutron counter based on beryllium activation, fast neutron pinhole camera based on small-area BCF-12 plastic scintillation detectors and high-speed four-frame soft X-ray camera with microchannel plate.

  13. Study of human factors and its basic aspects, focusing the operators of IEA-R1 research reactor

    International Nuclear Information System (INIS)

    Martins, Maria da Penha Sanches; Andrade, Delvonei Alves de

    2007-01-01

    The objective of this work is the study of human factors and situational variables, which, when modified, can interfere in the work actions of the operators of nuclear installations. This work is focused on the operators of the IEA-R1 research reactor, which is located in the Instituto de Pesquisas Energeticas e Nucleares - IPEN - CNEN/SP. The accidents in Nuclear Plants have shown that the most serious have occurred due to human failure. This work also considers the item 5.5.3 of CNEN-NN-3.01 standard - 'Actions must be taken to reduce, as much as possible, the human failures that may lead to accidents or even other events which may originate inadvertent or unintentional expositions in any individual'. The model named - Behavioral Analysis - is adopted. Relevant factors and aspects of the operators' routine are also considered. It is worth to remind that the performance depends on a series of variables, not only on the individual, but also the situational ones, which include physical, work, environment, organizational and social variables. Subjective factors are also considered, such as: attitude, ability, motivation etc., aiming at a global perspective of the situation, which counts on a set of principles for the behavior analysis and comprehension. After defining the applicability scenario, mechanisms and corrective actions to contribute with the reduction of failures will be proposed. (author)

  14. Department of the Air Force Supporting Data for Fiscal Year 1983, Budget Estimates Submitted to Congress February 1982. Descriptive Summaries. Research, Development, Test and Evaluation.

    Science.gov (United States)

    1982-02-01

    TACTICAL riCHTH Advanced Tactical Fighter. Joint Engine Development•• ADVANCED TACTICAL AH REC0NKAISSANC2 SYSTEM ( ATARS ). AIRCRAFT NOKNUCLEAR...1981 FY 1982 Title Actual Estimate TDTC FOR PROGRAM ELEMENT 116,435’ 135,999 Physics 12,994 14,657 Chemistry 11,926 13,778 Mathematics 10,700...to improved, stable spacecraft with extended life, Chemistry and materials research will focus on new ’«ramie, polymeric, and caroon-caroon concepts

  15. An open dialogue on the draft focus and themes for the next ITS strategic research plan : engaging stakeholders in their discussion and development.

    Science.gov (United States)

    2012-12-01

    The : purpose : of : this : document : is : to : identify : the : focus : and : themes : for : the : next : installment : of : the : ITS : Strategic : Research : Plan : and : to : invite : stakeholders : to : participate : in : their : discussion. : ...

  16. A practical approach to risk-benefit estimation in pediatric drug research.

    Science.gov (United States)

    Koren, Gideon

    2015-02-01

    One of the most difficult challenges in pediatric drug research is in exposing children to risk, often without a balanced chance of benefits. While the concept of risk is similar in adult research, the adult patient can decide for himself/herself on an acceptable level of risk, whereas children have to accept the decisions of their guardians. This paper attempts to put the complexities of estimating risk in pediatric drug research into their practical perspective, and to familiarize the reader with the way such processes are conducted in different parts of the world. Although there are regional differences, all authorities typically quantify risks of pediatric research in general, and drug research in particular, in three levels: those experienced in day-to-day life; risks slightly above this 'baseline' risk; and risks substantially above 'baseline risk'. Proportionally, the diligence of the ethics process depends on these levels, as well as on the potential benefits (or lack of) to the child involved in the research. Importantly, risk is context dependent, and a particular intervention may be effective or safe in one setting but not in another, based on local experience, staffing levels, and similar variabilities.

  17. Conceptual Design and Cost Estimate of a Subsonic NASA Testbed Vehicle (NTV) for Aeronautics Research

    Science.gov (United States)

    Nickol, Craig L.; Frederic, Peter

    2013-01-01

    A conceptual design and cost estimate for a subsonic flight research vehicle designed to support NASA's Environmentally Responsible Aviation (ERA) project goals is presented. To investigate the technical and economic feasibility of modifying an existing aircraft, a highly modified Boeing 717 was developed for maturation of technologies supporting the three ERA project goals of reduced fuel burn, noise, and emissions. This modified 717 utilizes midfuselage mounted modern high bypass ratio engines in conjunction with engine exhaust shielding structures to provide a low noise testbed. The testbed also integrates a natural laminar flow wing section and active flow control for the vertical tail. An eight year program plan was created to incrementally modify and test the vehicle, enabling the suite of technology benefits to be isolated and quantified. Based on the conceptual design and programmatic plan for this testbed vehicle, a full cost estimate of $526M was developed, representing then-year dollars at a 50% confidence level.

  18. Quantitative Risk reduction estimation Tool For Control Systems, Suggested Approach and Research Needs

    Energy Technology Data Exchange (ETDEWEB)

    Miles McQueen; Wayne Boyer; Mark Flynn; Sam Alessi

    2006-03-01

    For the past year we have applied a variety of risk assessment technologies to evaluate the risk to critical infrastructure from cyber attacks on control systems. More recently, we identified the need for a stand alone control system risk reduction estimation tool to provide owners and operators of control systems with a more useable, reliable, and credible method for managing the risks from cyber attack. Risk is defined as the probability of a successful attack times the value of the resulting loss, typically measured in lives and dollars. Qualitative and ad hoc techniques for measuring risk do not provide sufficient support for cost benefit analyses associated with cyber security mitigation actions. To address the need for better quantitative risk reduction models we surveyed previous quantitative risk assessment research; evaluated currently available tools; developed new quantitative techniques [17] [18]; implemented a prototype analysis tool to demonstrate how such a tool might be used; used the prototype to test a variety of underlying risk calculational engines (e.g. attack tree, attack graph); and identified technical and research needs. We concluded that significant gaps still exist and difficult research problems remain for quantitatively assessing the risk to control system components and networks, but that a useable quantitative risk reduction estimation tool is not beyond reach.

  19. A Method of Estimating Pressure and Intensity Distributions of Multielement Phased Array High Intensity Focused Ultrasonic Field at Full Power Using a Needle Hydrophone

    International Nuclear Information System (INIS)

    Yu Ying; Shen Guofeng; Bai Jingfeng; Chen Yazhu

    2011-01-01

    The pressure and intensity distribution of high intensity focused ultrasound (HIFU) fields at full power are critical for predicting heating patterns and ensuring safety of the therapy. With the limitations of maximum pressure at the hydrophone and damage from cavitation or thermal effects, it is hard to measure pressure and intensity directly when HIFU is at full power. HIFU-phased arrays are usually composed of large numbers of small elements and the sound power radiated from some of them at full power is measureable using a hydrophone, we grouped them based on the limitation of maximum permissible pressure at the hydrophone and the characteristics of the element arrangement in the array. Then sound field measurement of the group was carried out at full power level. Using the acoustic coherence principle, the pressure and intensity distribution of the array at full power level can be calculated from corresponding values from the groups. With this method, computer simulations and sound field measurement of a 65-element concentric distributed phased array was carried out. The simulation results demonstrate theoretically the feasibility of this method. Measurements on the 65-element phased array also verify the effectiveness of this method for estimating the pressure and intensity distribution of phased array at full power level using a needle hydrophone.

  20. Residual heat estimation by using Cherenkov radiation in Tehran Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Arkani, M. [Department of Nuclear Engineering, Azad University, Tehran (Iran, Islamic Republic of); Gharib, M. [Tehran Research Reactor, Nuclear Science and Technology Research Institute (NSTRI), Tehran 14395-836 (Iran, Islamic Republic of)], E-mail: mgharib@aeoi.org.ir

    2008-11-11

    An experiment is set up in Tehran 5 MW research reactor to observe Cherenkov radiation response during post-shutdown periods. An ordinary PC camera is used for this purpose. Theoretical estimation of the total power including decay heat and neutronic power is checked against detector response. A general agreement suggests that the same setup could equally serve as an independent channel for similar purposes in other reactors. This suggested that a similar setup based on present experience could be utilized in other reactors especially with the aim of fuel surveillance and monitoring.

  1. Research of Block-Based Motion Estimation Methods for Video Compression

    Directory of Open Access Journals (Sweden)

    Tropchenko Andrey

    2016-08-01

    Full Text Available This work is a review of the block-based algorithms used for motion estimation in video compression. It researches different types of block-based algorithms that range from the simplest named Full Search to the fast adaptive algorithms like Hierarchical Search. The algorithms evaluated in this paper are widely accepted by the video compressing community and have been used in implementing various standards, such as MPEG-4 Visual and H.264. The work also presents a very brief introduction to the entire flow of video compression.

  2. Residual heat estimation by using Cherenkov radiation in Tehran Research Reactor

    International Nuclear Information System (INIS)

    Arkani, M.; Gharib, M.

    2008-01-01

    An experiment is set up in Tehran 5 MW research reactor to observe Cherenkov radiation response during post-shutdown periods. An ordinary PC camera is used for this purpose. Theoretical estimation of the total power including decay heat and neutronic power is checked against detector response. A general agreement suggests that the same setup could equally serve as an independent channel for similar purposes in other reactors. This suggested that a similar setup based on present experience could be utilized in other reactors especially with the aim of fuel surveillance and monitoring.

  3. A stepwise validation of a wearable system for estimating energy expenditure in field-based research

    International Nuclear Information System (INIS)

    Rumo, Martin; Mäder, Urs; Amft, Oliver; Tröster, Gerhard

    2011-01-01

    Regular physical activity (PA) is an important contributor to a healthy lifestyle. Currently, standard sensor-based methods to assess PA in field-based research rely on a single accelerometer mounted near the body's center of mass. This paper introduces a wearable system that estimates energy expenditure (EE) based on seven recognized activity types. The system was developed with data from 32 healthy subjects and consists of a chest mounted heart rate belt and two accelerometers attached to a thigh and dominant upper arm. The system was validated with 12 other subjects under restricted lab conditions and simulated free-living conditions against indirect calorimetry, as well as in subjects' habitual environments for 2 weeks against the doubly labeled water method. Our stepwise validation methodology gradually trades reference information from the lab against realistic data from the field. The average accuracy for EE estimation was 88% for restricted lab conditions, 55% for simulated free-living conditions and 87% and 91% for the estimation of average daily EE over the period of 1 and 2 weeks

  4. Plasma Focus

    International Nuclear Information System (INIS)

    Bernard, Alain; Jolas, Alain; Garconnet, J.-P.; Mascureau, J. de; Nazet, Christian; Coudeville, Alain; Bekiarian, Andre.

    1977-01-01

    The present report is the edition of the lectures given in a conference on the Focus experiment held at the Centre d'etudes de Limeil, on Oct. 1975. After a survey of the early laboratories one will find the main results obtained in Limeil concerning interferometry, laser scattering, electric and magnetic-measurements, X-ray and neutron emission and also the possible use of explosive current generators instead of capacitor banks at high energy levels. The principal lines of future research are given in the conclusion [fr

  5. Translational Researchers' Perceptions of Data Management Practices and Data Curation Needs: Findings from a Focus Group in an Academic Health Sciences Library

    Science.gov (United States)

    Bardyn, Tania P.; Resnick, Taryn; Camina, Susan K.

    2012-01-01

    How translational researchers use data is becoming an important support function for libraries to understand. Libraries' roles in this increasingly complex area of Web librarianship are often unclearly defined. The authors conducted two focus groups with physicians and researchers at an academic medical center, the UCLA David Geffen School of…

  6. A focus on the state of the art of food waste/losses issue and suggestions for future researches.

    Science.gov (United States)

    Muriana, Cinzia

    2017-10-01

    Today, the role of the supply chain (SC) strategies in Food-Waste/Losses (F-W/L) generation is neglected, because F-W/L are generally considered an unavoidable consequence of accidental events. Therefore, only operating plans are today put into practice, which aim at reducing the impact of product losses along the SC. This involves that structured analyses and strategic SC approaches are not available for the prevention/minimization of F-W/L. The paper aims at changing the perspective, and promoting the hypothesis that generation of F-W/L mainly depends on the SC strategies put into practice that are usually optimized on the basis of the market demand. The paper considers the F-W/L an intrinsic characteristic of the SC, which must be put in relation with the market demand and the shelf life of products, for given boundary conditions (legal constraints, politic decisions, climatic and micro macro-economic factors). Thus, the paper aims at reviewing the state of the art of the F-W/L issue, and proposing new research topics in the field of the prevention and minimization of F-W/L, by focusing on: (i) the forecasting of F-W/L, the implementation of adaptive-holistic approaches that model the non-stationary and holistic behaviour of the phenomenon; (ii) the determination of analytical conditions that entail the generation of F-W/L, in relation to the implementation of specific SC strategies; (iii) the study of mathematical models for the assessment of the shelf life, and the evaluation of innovative technologies, which enable the shelf life monitoring; (iv) the study of new shelf life-dependent demand models based on the consumer-utility theory; (v) the redesign of the logistic SC management models, by proposing new SC coordination models, planning and replenishment strategies, and pricing models, for the prevention/minimization of the predictable component of F-W/L; (vi) the design of new risk assessment plans for the management of the accidental component of F

  7. Extracting objective estimates of sedentary behavior from accelerometer data: measurement considerations for surveillance and research applications.

    Directory of Open Access Journals (Sweden)

    Youngdeok Kim

    Full Text Available Accelerometer-based activity monitors are widely used in research and surveillance applications for quantifying sedentary behavior (SB and physical activity (PA. Considerable research has been done to refine methods for assessing PA, but relatively little attention has been given to operationalizing SB parameters (i.e., sedentary time and breaks from accelerometer data - particularly in relation to health outcomes. This study investigated: (a the accrued patterns of sedentary time and breaks; and (b the associations of sedentary time and breaks in different bout durations with cardiovascular risk factors.Accelerometer data on 5,917 adults from the National Health Examination and Nutrition Survey (NHANES 2003-2006 were used. Sedentary time and breaks at different bout durations (i.e., 1, 2-4, 5-9, 10-14, 15-19, 20-24, 25-29, and ≥ 30-min were obtained using a threshold of < 100 counts per minute. Sedentary time and breaks were regressed on cardiovascular risk factors (waist circumference, triglyceride, and high-density lipoprotein cholesterol and body mass index across bout durations.The results revealed that the majority of sedentary time occurred within relatively short bout durations (≈ 70% and ≈ 85% for < 5-min and < 10-min, respectively. The associations of sedentary time and breaks with health outcomes varied depending on how bout time was defined. Estimates of SB parameters based on bout durations of 5 min or shorter were associated with reduced cardiovascular risk factors while durations longer than 10-min were generally associated with increased risk factors.The present study demonstrates that the duration of sedentary bouts should be further considered when operationalizing the SB parameters from accelerometer data. The threshold of 5 minutes to define a bout is defensible, but a 10 minute threshold would provide a more conservative estimate to clearly capture the prolonged nature of sedentary behavior. Additional research is

  8. Trends in Research on the Security of Medical Information in Korea: Focused on Information Privacy Security in Hospitals.

    Science.gov (United States)

    Kim, Yong-Woon; Cho, Namin; Jang, Hye-Jung

    2018-01-01

    Information technology involves a risk of privacy violation in providing easy access to confidential information,such as personal information and medical information through the Internet. In this study, we investigated medical information security to gain a better understanding of trends in research related to medical information security. We researched papers published on '의료정보' and 'medical information' in various Korean journals during a 10-year period from 2005 to 2015. We also analyzed these journal papers for each fiscal year; these papers were categorized into the areas of literature research and empirical research, and were further subdivided according to themes and subjects. It was confirmed that 48 papers were submitted to 35 academic journals. There were 33 (68.8%) literature review articles, and analysis of secondary data was not carried out at all. In terms of empirical research, 8 (16.7%) surveys and 7 (14.6%) program developments were studied. As a result of analyzing these papers according to the research theme by research method, 17 (35.4%) papers on laws, systems, and policies were the most numerous. It was found that among the literature research papers on medical personnel were the most common, and among the empirical research papers, research on experts in information protection and medical personnel were the most common. We suggest that further research should be done in terms of social perception, human resource development, and technology development to improve risk management in medical information systems.

  9. Without 'Focus'

    Directory of Open Access Journals (Sweden)

    Aldo Sevi

    2010-12-01

    Full Text Available It is widely accepted that a notion of 'focus', more or less as conceived of in Jackendoff (1972, must be incorporated into our theory of grammar, as a means of accounting for certain observed correlations between prosodic facts and semantic/pragmatic facts. In this paper, we put forth the somewhat radical idea that the time has come to give up this customary view, and eliminate 'focus' from our theory of grammar. We argue that such a move is both economical and fruitful.Research over the years has revealed that the correlations between prosody, 'focus', and the alleged semantic/pragmatic effects of focus are much less clear and systematic than we may have initially hoped. First we argue that this state of affairs detracts significantly from the utility of our notion of 'focus', to the point of calling into question the very motivation for including it in the grammar. Then we look at some of the central data, and show how they might be analyzed without recourse to a notion of 'focus'. We concentrate on (i the effect of pitch accent placement on discourse congruence, and (ii the choice of 'associate' for the so-called 'focus sensitive' adverb only. We argue that our focus-free approach to the data improves empirical coverage, and begins to reveal patterns that have previously been obscured by preconceptions about 'focus'.ReferencesBeaver, D. & Clark, B. 2008. Sense and Sensitivity: How Focus Determines Meaning. Blackwell.Beaver, D., Clark, B., Flemming, E., Jaeger, T. F. & Wolters, M. 2007. ‘When semantics meets phonetics: Acoustical studies of second occurrence focus’. Language 83.2: 245–76.http://dx.doi.org/10.1353/lan.2007.0053Beckman, M. & Hirschberg, J. 1994. ‘The ToBI Annotation Conventions’. Ms.,http://www.cs.columbia.edu/~julia/files/conv.pdf.Bolinger, D. 1972. ‘Accent is predictable (if you are a mind-reader’. Language 48.3: 633–44.http://dx.doi.org/10.2307/412039Büring, D. 2006. ‘Focus projection and default

  10. Two-Stage Residual Inclusion Estimation in Health Services Research and Health Economics.

    Science.gov (United States)

    Terza, Joseph V

    2018-06-01

    Empirical analyses in health services research and health economics often require implementation of nonlinear models whose regressors include one or more endogenous variables-regressors that are correlated with the unobserved random component of the model. In such cases, implementation of conventional regression methods that ignore endogeneity will likely produce results that are biased and not causally interpretable. Terza et al. (2008) discuss a relatively simple estimation method that avoids endogeneity bias and is applicable in a wide variety of nonlinear regression contexts. They call this method two-stage residual inclusion (2SRI). In the present paper, I offer a 2SRI how-to guide for practitioners and a step-by-step protocol that can be implemented with any of the popular statistical or econometric software packages. We introduce the protocol and its Stata implementation in the context of a real data example. Implementation of 2SRI for a very broad class of nonlinear models is then discussed. Additional examples are given. We analyze cigarette smoking as a determinant of infant birthweight using data from Mullahy (1997). It is hoped that the discussion will serve as a practical guide to implementation of the 2SRI protocol for applied researchers. © Health Research and Educational Trust.

  11. Gamma exposure rate estimation in irradiation facilities of nuclear research reactors

    International Nuclear Information System (INIS)

    Daoud, Adrian

    2009-01-01

    There are experimental situations in the nuclear field, in which dose estimations due to energy-dependent radiation fields are required. Nuclear research reactors provide such fields under normal operation or due to radioactive disintegration of fission products and structural materials activation. In such situations, it is necessary to know the exposure rate of gamma radiation the different materials under experimentation are subject to. Detectors of delayed reading are usually used for this purpose. Direct evaluation methods using portable monitors are not always possible, because in some facilities the entrance with such devices is often impracticable and also unsafe. Besides, these devices only provide information of the place where the measurement was performed, but not of temporal and spatial fluctuations the radiation fields could have. In this work a direct evaluation method was developed for the 'in-situ' gamma exposure rate for the irradiation facilities of the RA-1 reactor. This method is also applicable in any similar installation, and may be complemented by delayed evaluations without problem. On the other hand, it is well known that the residual effect of radiation modifies some properties of the organic materials used in reactors, such as density, colour, viscosity, oxidation level, among others. In such cases, a correct dosimetric evaluation enables in service estimation of material duration with preserved properties. This evaluation is for instance useful when applied to lubricating oils for the primary circuit pumps in nuclear power plants, thus minimizing waste generation. In this work the necessary elements required to estimate in-situ time and space integrated dose are also established for a gamma irradiated sample in an irradiation channel of a nuclear facility with zero neutron flux. (author)

  12. Estimation of metal pollutant loads from Nuclear and Energy Research Institute (Brazil)

    Energy Technology Data Exchange (ETDEWEB)

    Marques, Joyce R.; Monteiro, Lucilena R.; Soares, Sabrina M.V.; Stellato, Thamiris B.; Silva, Tatiane B.S.C.; Silva, Douglas B. da; Faustino, Mainara G.; Pires, Maria A.F.; Cotrim, Marycel E.B., E-mail: joyce.marques@usp.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    According to National Environmental Council's (CONAMA) Resolution 357/05, pollutant load can be defined as the amount of a particular pollutant released in receiving water body; it is commonly expressed in a mass-time ratio. As specified in CONAMA's Resolution 430/11, the responsible for the pollutant source must present the Pollutant Load Declaration to environmental authorities. However, pollutant load knowledge is also important to the water quality maintenance and its environmental rating that must be kept to meet the requirements of the most restrictive use. In the control of metals releases is also important due public health matters, since they can cause harmful environmental contamination and major public health issues. Therefore this work aims to present the estimated metal pollutant load released by Nuclear and Energy Research Institute (IPEN/CNEN - Brazil), between 2013 and 2014. Results of cadmium, lead, copper, chromium, zinc, nickel, manganese, iron, barium, silver, boron and tin in composite samples (weekly) via Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) and bromide (Br-) released as a tracer, to measure the wastewater flow were used to estimate IPEN's Metal Pollutant load. This study is part of the environmental assessment Program at IPEN, instituted since 2006 to the attendance of the current environmental legislation (CONAMA's Resolution 430/11, Article 19-A of State Decree 8.468/76 and State Decree 15.425/80). (author)

  13. Estimation of dynamic rotor loads for the rotor systems research aircraft: Methodology development and validation

    Science.gov (United States)

    Duval, R. W.; Bahrami, M.

    1985-01-01

    The Rotor Systems Research Aircraft uses load cells to isolate the rotor/transmission systm from the fuselage. A mathematical model relating applied rotor loads and inertial loads of the rotor/transmission system to the load cell response is required to allow the load cells to be used to estimate rotor loads from flight data. Such a model is derived analytically by applying a force and moment balance to the isolated rotor/transmission system. The model is tested by comparing its estimated values of applied rotor loads with measured values obtained from a ground based shake test. Discrepancies in the comparison are used to isolate sources of unmodeled external loads. Once the structure of the mathematical model has been validated by comparison with experimental data, the parameters must be identified. Since the parameters may vary with flight condition it is desirable to identify the parameters directly from the flight data. A Maximum Likelihood identification algorithm is derived for this purpose and tested using a computer simulation of load cell data. The identification is found to converge within 10 samples. The rapid convergence facilitates tracking of time varying parameters of the load cell model in flight.

  14. The Precision of Effect Size Estimation From Published Psychological Research: Surveying Confidence Intervals.

    Science.gov (United States)

    Brand, Andrew; Bradley, Michael T

    2016-02-01

    Confidence interval ( CI) widths were calculated for reported Cohen's d standardized effect sizes and examined in two automated surveys of published psychological literature. The first survey reviewed 1,902 articles from Psychological Science. The second survey reviewed a total of 5,169 articles from across the following four APA journals: Journal of Abnormal Psychology, Journal of Applied Psychology, Journal of Experimental Psychology: Human Perception and Performance, and Developmental Psychology. The median CI width for d was greater than 1 in both surveys. Hence, CI widths were, as Cohen (1994) speculated, embarrassingly large. Additional exploratory analyses revealed that CI widths varied across psychological research areas and that CI widths were not discernably decreasing over time. The theoretical implications of these findings are discussed along with ways of reducing the CI widths and thus improving precision of effect size estimation.

  15. Improved Monte Carlo-perturbation method for estimation of control rod worths in a research reactor

    International Nuclear Information System (INIS)

    Kalcheva, Silva; Koonen, Edgar

    2009-01-01

    A hybrid method dedicated to improve the experimental technique for estimation of control rod worths in a research reactor is presented. The method uses a combination of Monte Carlo technique and perturbation theory. Perturbation method is used to obtain the equation for the relative efficiency of control rod insertion. A series of coefficients, describing the axial absorption profile are used to correct the equation for a composite rod, having a complicated burn-up irradiation history. These coefficients have to be determined - by experiment or by using some theoretical/numerical method. In the present paper they are derived from the macroscopic absorption cross-sections, obtained from detailed Monte Carlo calculations by MCNPX 2.6.F of the axial burn-up profile during control rod life. The method is validated on measurements of control rod worths at the BR2 reactor. Comparison with direct MCNPX evaluations of control rod worths is also presented

  16. Student teaching and research laboratory focusing on brain-computer interface paradigms--A creative environment for computer science students.

    Science.gov (United States)

    Rutkowski, Tomasz M

    2015-08-01

    This paper presents an applied concept of a brain-computer interface (BCI) student research laboratory (BCI-LAB) at the Life Science Center of TARA, University of Tsukuba, Japan. Several successful case studies of the student projects are reviewed together with the BCI Research Award 2014 winner case. The BCI-LAB design and project-based teaching philosophy is also explained. Future teaching and research directions summarize the review.

  17. ESTIMATION OF SURVIVAL IN PATIENTS WITH ADVANCED OVARIAN CANCER – ABSTRACT OF THE RESEARCH PROJECT

    Directory of Open Access Journals (Sweden)

    Špela Smrkolj

    2018-02-01

    Full Text Available Background: Morbidity and mortality caused by cancer persist to be an important health problem world- wide and in the European Union member states as well. In Slovenia, most ovarian cancer cases are detected in advanced stages, hence a rather high mortality rate. Aims: The purpose of this research project is to analyze the primary cytoreduction in the patients with advanced ovarian cancer. The main objective of the project is to assess the use of lap- aroscopy in the prediction of optimal cytoreduction in these patients. Applicative research project ‘Estimation of survial in patients with advanced ovarian can- cer based on primary laparoscopical assessment of optimal cytoreduction’ (L3-2371 was approved and has been financed by the Slovene Research Agency and co-financed by the Ministry of Health of RS; Duration: May 1, 2009–April 30, 2012. Methods: The research project will consist of retrospective and prospective study. In all the patients with advanced ovarian cancer managed at the Department of Obstetrics and Gynecol- ogy, University Medical Centre Ljubljana in the years 2003–2008, and in whom optimal primary cytoreduction was made using either laparoscopy or laparotomy, certain clinical and pathomorphological factors will be compared, and the effects of all analyzed factors on the outcome of treatment assessed. In the prospective study, we will aim at assessing the use of laparoscopy in the prediction of optimal cytoreduction in all newly detected cases using a laparoscopy-based score (Fagotti’s scoring system. Conclusions: The standard management of advanced ovarian cancer patients consists of primary surgical optimal and/or suboptimal cytoreduction followed by aggressive cytotoxic chemotherapy. In line with our experience and with that published most recently, laparoscopy seems to be a promising method with which we will attempt to most accurately assess the optimal cytoreduction in surgical treatment of ovarian cancer patients.

  18. Estimation of the future nuclear power research in Romania, based on the present Cernavoda NPP evolution

    International Nuclear Information System (INIS)

    Dumitrache, Ion

    2001-01-01

    For more than four decades, the electric power needs of Romania were evaluated on the basis of the State Plan for Economic Development. To identify the optimal solution, the 'least price per produced MWh' was practically the only criterion. Now, there is no convincing estimation of the future economic development and at least two additional criteria play a significant role, 'the safety in the supply of the needed electric power', and 'the need of limiting the environmental impact of electricity generation'. The analysis dedicated to evaluation of future electric power solutions must take into account several features of the present situation. There are no available internal funds to finance the construction of new generating units of the order of several hundreds of MW. Even the so-called 'refurbishing' of the existing thermal power plants is based on foreign loan. In the 2000 year, about 80 electricity generation units reached 30 years of operation, i.e., the design life. Other thermal power plants proved very modest performances during 15-20 years of operation. Consequently, the future of almost 100 generating units is either in shutdown + decommissioning or shutdown + modernization situation. The Government analyzed the situation and decided to continue the completion of the Cernavoda NPP. The Unit 2 will be commissioned in a couple of years, and there is a schedule of negotiations relating the future of the Unit 3. After almost five years of successful operation of the Unit 1, the collaboration between RDT Institutes and NPP has clear features. Based on the experience related to this collaboration and taking into account the evolution of the Cernavoda NPP, we estimated that five research domains have significant chances to obtain a stable (and, hopefully, consistent) financial support. 1. Nuclear Safety, in particular Accident Analysis. As the Government re-iterated the firm decision to meet the conditions required for European integration, most of the nuclear

  19. Felt Stigma in Injection Drug Users and Sex Workers: Focus Group Research with HIV-Risk Populations in Puerto Rico.

    Science.gov (United States)

    Jiménez, Julio; Puig, Marieva; Sala, Ana Cecilia; Ramos, Juan Carlos; Castro, Eida; Morales, Marangelie; Santiago, Lydia; Zorrilla, Carmen

    Though many studies have conclusively linked felt stigma and HIV, few have focused on the experiences of rejection felt by members of such socially marginalized groups as intravenous drug users (IDU) and sex workers (SW). Using focus groups, our study explored these experiences in 34 individuals (17 male UDUs and 17 female SWs) at risk of becoming infected with HIV, the objective being to discover why they engaged in maladaptive behaviors as a way of coping with felt stigma. We used deductive and inductive analysis to codify the resulting data. Concepts associated with the word stigma, emotional reactions to felt stigma, and the impact of felt stigma on self-schema helped elucidate how the internalization of felt stigma can lead to negative affective states and self-destructive behaviors (e.g., drug use and syringe exchange). Results underline the importance of developing intervention models that reduce stigma as a means of HIV prevention in vulnerable populations.

  20. The Body as a Substrate of Differentiation. Shifting the Focus from Race Science to Life Scientists' Research on Human Variation

    OpenAIRE

    Lipphardt, Veronika

    2017-01-01

    Abstract This article suggests to focus on the history of human variation instead of focussing on the history of race science. It views the latter as a subset of the former, hence views race science as embedded into the larger field of life scientists' investigations into human variation. This paper explores why human variation is such an attractive and productive object particularly for the life sciences. It proposes that knowledge about human variation is incomplete in a promising way, and ...

  1. Swelling Estimation of Multi-wire U-Mo Monolithic Fuel for HANARO Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Yoon-Sang; Ryu, Ho-Jin; Park, Jong-Man; Oh, Jong-Myeong; Kim, Chang-Kyu [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2008-10-15

    In order to use low-enriched uranium (LEU) instead of highly enriched uranium (HEU) for high performance research reactors, the reduced enrichment for research and test reactors (RERTR) program is developing high uranium density fuel such as U-Mo/Al dispersion fuel. U-Mo alloys have an excellent irradiation performance when compared to other uranium alloys or compounds. But the results from the post-irradiation examination of the U-Mo/Al dispersion fuels indicate that an interaction between the U-Mo alloy fuel and the Al matrix phases occurs readily during an irradiation and it is sensitively dependent on the temperature. In order to lessen these severe interactions, a concept of a multi-wire type fuel was proposed. The fuel configuration is that three to six U-Mo fuel wires (1.5 mm - 2 mm in diameter) are symmetrically arranged at the periphery side in the Al matrix. In this study temperature calculations and a swelling estimation of a multi-wire monolithic fuel were carried out. Also the results of a post irradiation analysis of this fuel will be introduced.

  2. A guide to writing a scientific paper: a focus on high school through graduate level student research.

    Science.gov (United States)

    Hesselbach, Renee A; Petering, David H; Berg, Craig A; Tomasiewicz, Henry; Weber, Daniel

    2012-12-01

    This article presents a detailed guide for high school through graduate level instructors that leads students to write effective and well-organized scientific papers. Interesting research emerges from the ability to ask questions, define problems, design experiments, analyze and interpret data, and make critical connections. This process is incomplete, unless new results are communicated to others because science fundamentally requires peer review and criticism to validate or discard proposed new knowledge. Thus, a concise and clearly written research paper is a critical step in the scientific process and is important for young researchers as they are mastering how to express scientific concepts and understanding. Moreover, learning to write a research paper provides a tool to improve science literacy as indicated in the National Research Council's National Science Education Standards (1996), and A Framework for K-12 Science Education (2011), the underlying foundation for the Next Generation Science Standards currently being developed. Background information explains the importance of peer review and communicating results, along with details of each critical component, the Abstract, Introduction, Methods, Results, and Discussion. Specific steps essential to helping students write clear and coherent research papers that follow a logical format, use effective communication, and develop scientific inquiry are described.

  3. Application of best estimate thermalhydraulic codes for the safety analysis of research reactors

    International Nuclear Information System (INIS)

    Adorni, M.; Bousbia-salah, A.; D'Auria, F.; Hamidouche, T.

    2006-01-01

    An established international expertise in relation to computational tools, procedures for their application including Best Estimate (BE) methods supported by uncertainty evaluation, and comprehensive experimental database exists within the safety technology of Nuclear Power Plant (NPP). The importance of transferring NPP safety technology tools and methods to RR safety technology has been noted in recent IAEA activities. However, the ranges of parameters of interest to RR are different from those for NPP: this is namely true for fuel composition, system pressure, adopted materials and overall system geometric configuration. The large variety of research reactors prevented so far the achievement of systematic and detailed lists of initiating events based upon qualified Probabilistic Safety Assessment (PSA) studies with results endorsed by the international community. However, bounding and generalized lists of events are available from IAEA documents and can be considered for deeper studies in the area. In the area of acceptance criteria, established standards accepted by the international community are available. Therefore no major effort is needed, but an effort appears worthwhile to check that those standards are adopted and that the related thresholds are fulfilled. The importance of suitable experimental assessment is recognized. A large amount of data exists as the kinetic dynamic core behaviour form SPERT reactors tests. However, not all data are accessible to all institutions and the relationship between the range of parameters of experiments and the range of parameters relevant to RR technology is not always established. However, code-assessment through relevant set of experimental data are recorded and properly stored. An established technology exists for development, qualification and application of system thermal-hydraulics codes suitable to be adopted for accident analysis in research reactors. This derives from NPP technology. The applicability of

  4. Re-appraisal and extension of the Gratton-Vargas two-dimensional analytical snowplow model of plasma focus evolution in the context of contemporary research

    International Nuclear Information System (INIS)

    Auluck, S. K. H.

    2013-01-01

    Recent resurgence of interest in applications of dense plasma focus and doubts about the conventional view of dense plasma focus as a purely irrotational compressive flow have re-opened questions concerning device optimization. In this context, this paper re-appraises and extends the analytical snowplow model of plasma focus sheath evolution developed by F. Gratton and J. M. Vargas [Energy Storage, Compression and Switching, edited by V. Nardi, H. Sahlin, and W. H. Bostick (Plenum, New York, 1983), Vol. 2, p. 353)] and shows its relevance to contemporary research. The Gratton-Vargas (GV) model enables construction of a special orthogonal coordinate system in which the plasma flow problem can be simplified and a model of sheath structure can be formulated. The Lawrenceville Plasma Physics (LPP) plasma focus facility, which reports neutron yield better than global scaling law, is shown to be operating closer to an optimum operating point of the GV model as compared with PF-1000

  5. Estimating resting motor thresholds in transcranial magnetic stimulation research and practice: a computer simulation evaluation of best methods.

    Science.gov (United States)

    Borckardt, Jeffrey J; Nahas, Ziad; Koola, Jejo; George, Mark S

    2006-09-01

    Resting motor threshold is the basic unit of dosing in transcranial magnetic stimulation (TMS) research and practice. There is little consensus on how best to estimate resting motor threshold with TMS, and only a few tools and resources are readily available to TMS researchers. The current study investigates the accuracy and efficiency of 5 different approaches to motor threshold assessment for TMS research and practice applications. Computer simulation models are used to test the efficiency and accuracy of 5 different adaptive parameter estimation by sequential testing (PEST) procedures. For each approach, data are presented with respect to the mean number of TMS trials necessary to reach the motor threshold estimate as well as the mean accuracy of the estimates. A simple nonparametric PEST procedure appears to provide the most accurate motor threshold estimates, but takes slightly longer (on average, 3.48 trials) to complete than a popular parametric alternative (maximum likelihood PEST). Recommendations are made for the best starting values for each of the approaches to maximize both efficiency and accuracy. In light of the computer simulation data provided in this article, the authors review and suggest which techniques might best fit different TMS research and clinical situations. Lastly, a free user-friendly software package is described and made available on the world wide web that allows users to run all of the motor threshold estimation procedures discussed in this article for clinical and research applications.

  6. Medical records confidentiality and public health research: two values at stake? An italian survey focus on individual preferences

    Directory of Open Access Journals (Sweden)

    Virgilia Toccaceli

    2015-02-01

    Full Text Available In a time when Europe is preparing to introduce new regulations on privacy protection, we conducted a survey among 1700 twins enrolled in the Italian Twin Register about the access and use of their medical records for public health research without explicit informed consent. A great majority of respondents would refuse or are doubtful about the access and use of hospital discharge records or clinical data without their explicit consent. Young and female individuals represent the modal profile of these careful people. As information retrieved from medical records is crucial for progressing knowledge, it is important to promote a better understanding of the value of public health research activities among the general population. Furthermore, public opinions are relevant to policy making, and concerns and preferences about privacy and confidentiality in research can contribute to the design of procedures to exploit medical records effectively and customize the protection of individuals’ medical data.

  7. Focus on CSIR research in water resources: Modelling complex biophysical processes associated with diseases. Case study: the ecology of vibriocholerae in the Mozambican channel

    CSIR Research Space (South Africa)

    Du Preez, M

    2007-08-01

    Full Text Available will be undertaken. Non-linear dynamics and chaos theory will be applied to enhance our understanding of the link between the microbial ecology, remote sensing and meteorological data. Focus on CSIR Research in Water Resources Contact details: CSIR Natural...

  8. A critical reflection on the use of focus groups as a research method: lessons from trying to hear the voices of NGO beneficiaries in Ghana

    NARCIS (Netherlands)

    Agyemang, G.; Awumbila, M.; O'Dwyer, B.

    2009-01-01

    The focus group method has been used extensively in social science research in order to gain a deep understanding of participant perceptions of specific topics of interest. However, the method has rarely been used in the social accounting and accountability literature. This paper reviews and

  9. Estimating the returns to United Kingdom publicly funded musculoskeletal disease research in terms of net value of improved health outcomes.

    Science.gov (United States)

    Glover, Matthew; Montague, Erin; Pollitt, Alexandra; Guthrie, Susan; Hanney, Stephen; Buxton, Martin; Grant, Jonathan

    2018-01-10

    Building on an approach applied to cardiovascular and cancer research, we estimated the economic returns from United Kingdom public- and charitable-funded musculoskeletal disease (MSD) research that arise from the net value of the improved health outcomes in the United Kingdom. To calculate the economic returns from MSD-related research in the United Kingdom, we estimated (1) the public and charitable expenditure on MSD-related research in the United Kingdom between 1970 and 2013; (2) the net monetary benefit (NMB), derived from the health benefit in quality adjusted life years (QALYs) valued in monetary terms (using a base-case value of a QALY of £25,000) minus the cost of delivering that benefit, for a prioritised list of interventions from 1994 to 2013; (3) the proportion of NMB attributable to United Kingdom research; and (4) the elapsed time between research funding and health gain. The data collected from these four key elements were used to estimate the internal rate of return (IRR) from MSD-related research investments on health benefits. We analysed the uncertainties in the IRR estimate using a one-way sensitivity analysis. Expressed in 2013 prices, total expenditure on MSD-related research from 1970 to 2013 was £3.5 billion, and for the period used to estimate the rate of return, 1978-1997, was £1.4 billion. Over the period 1994-2013 the key interventions analysed produced 871,000 QALYs with a NMB of £16 billion, allowing for the net NHS costs resulting from them and valuing a QALY at £25,000. The proportion of benefit attributable to United Kingdom research was 30% and the elapsed time between funding and impact of MSD treatments was 16 years. Our best estimate of the IRR from MSD-related research was 7%, which is similar to the 9% for CVD and 10% for cancer research. Our estimate of the IRR from the net health gain to public and charitable funding of MSD-related research in the United Kingdom is substantial, and justifies the research investments

  10. A Meta-Analysis of Distributed Leadership from 2002 to 2013: Theory Development, Empirical Evidence and Future Research Focus

    Science.gov (United States)

    Tian, Meng; Risku, Mika; Collin, Kaija

    2016-01-01

    This article provides a meta-analysis of research conducted on distributed leadership from 2002 to 2013. It continues the review of distributed leadership commissioned by the English National College for School Leadership (NCSL) ("Distributed Leadership: A Desk Study," Bennett et al., 2003), which identified two gaps in the research…

  11. The Influence of Power Shifts in Data Collection and Analysis Stages: A Focus on Qualitative Research Interview

    Science.gov (United States)

    Anyan, Frederick

    2013-01-01

    This paper analyzes the power relation between the interviewer and the interviewee in the qualitative research interview methodology. The paper sets out to grapple with the extent to which the dynamisms in power shifts influence data collection and analysis in the interview methodology. The exploration of power shifts in the qualitative research…

  12. Research Productivity in Rehabilitation, Disability, and Allied Health Programs: A Focus Group Perspective on Minority-Serving Institutions

    Science.gov (United States)

    Aref, Fariborz; Manyibe, Edward O.; Washington, Andre L.; Johnson, Jean; Davis, Dytisha; Eugene-Cross, Kenyotta; Moore, Cayla A.

    2017-01-01

    Purpose: The article outlines select individual and institutional factors that could contribute to rehabilitation, disability, and health research productivity among minority-serving institutions (MSIs; i.e., historically Black colleges/universities, Hispanic-serving institutions, and American Indian tribal colleges/universities). Method: We…

  13. Qualitative to Quantitative and Spectrum to Report: An Instrument-Focused Research Methods Course for First-Year Students

    Science.gov (United States)

    Thomas, Alyssa C.; Boucher, Michelle A.; Pulliam, Curtis R.

    2015-01-01

    Our Introduction to Research Methods course is a first-year majors course built around the idea of helping students learn to work like chemists, write like chemists, and think like chemists. We have developed this course as a hybrid hands-on/ lecture experience built around instrumentation use and report preparation. We take the product from one…

  14. Left Brain/Right Brain: Research and Learning. Focused Access to Selected Topics (FAST) Bibliography No. 12.

    Science.gov (United States)

    Eppele, Ruth

    This 27-item bibliography represents the variety of articles added to the ERIC database from 1983 through 1988 on left-brain/right-brain research, theory, and application as it relates to classroom incorporation. Included are conflicting opinions as to the usefulness of left-brain/right-brain studies and their application in the learning…

  15. The Contribution of Mixed Methods Research to the Field of Childhood Trauma: A Narrative Review focused on Data Integration

    NARCIS (Netherlands)

    Boeije, H.R.; Slagt, M.I.; van Wesel, F.

    2013-01-01

    In mixed methods research (MMR), integrating the quantitative and the qualitative components of a study is assumed to result in additional knowledge (or "yield"). This narrative review examines the extent to which MMR is used in the field of childhood trauma and provides directions for improving

  16. The contribution of mixed methods research to the field of childhood trauma: a narrative review focused on data integration.

    NARCIS (Netherlands)

    Boeije, H.; Slagt, M.; Wesel, F. van

    2013-01-01

    In mixed methods research (MMR), integrating the quantitative and the qualitative components of a study is assumed to result in additional knowledge (or “yield”). This narrative review examines the extent to which MMR is used in the field of childhood trauma and provides directions for improving

  17. The Contribution of Mixed Methods Research to the Field of Childhood Trauma: A Narrative Review Focused on Data Integration

    Science.gov (United States)

    Boeije, Hennie; Slagt, Meike; van Wesel, Floryt

    2013-01-01

    In mixed methods research (MMR), integrating the quantitative and the qualitative components of a study is assumed to result in additional knowledge (or "yield"). This narrative review examines the extent to which MMR is used in the field of childhood trauma and provides directions for improving mixed methods studies in this field. A…

  18. Estimating rainforest biomass stocks and carbon loss from deforestation and degradation in Papua New Guinea 1972-2002: Best estimates, uncertainties and research needs.

    Science.gov (United States)

    Bryan, Jane; Shearman, Phil; Ash, Julian; Kirkpatrick, J B

    2010-01-01

    Reduction of carbon emissions from tropical deforestation and forest degradation is being considered a cost-effective way of mitigating the impacts of global warming. If such reductions are to be implemented, accurate and repeatable measurements of forest cover change and biomass will be required. In Papua New Guinea (PNG), which has one of the world's largest remaining areas of tropical forest, we used the best available data to estimate rainforest carbon stocks, and emissions from deforestation and degradation. We collated all available PNG field measurements which could be used to estimate carbon stocks in logged and unlogged forest. We extrapolated these plot-level estimates across the forested landscape using high-resolution forest mapping. We found the best estimate of forest carbon stocks contained in logged and unlogged forest in 2002 to be 4770 Mt (+/-13%). Our best estimate of gross forest carbon released through deforestation and degradation between 1972 and 2002 was 1178 Mt (+/-18%). By applying a long-term forest change model, we estimated that the carbon loss resulting from deforestation and degradation in 2001 was 53 Mt (+/-18%), rising from 24 Mt (+/-15%) in 1972. Forty-one percent of 2001 emissions resulted from logging, rising from 21% in 1972. Reducing emissions from logging is therefore a priority for PNG. The large uncertainty in our estimates of carbon stocks and fluxes is primarily due to the dearth of field measurements in both logged and unlogged forest, and the lack of PNG logging damage studies. Research priorities for PNG to increase the accuracy of forest carbon stock assessments are the collection of field measurements in unlogged forest and more spatially explicit logging damage studies. Copyright 2009 Elsevier Ltd. All rights reserved.

  19. Privilege and status in an unequal society: shifting the focus of health promotion research to include the maintenance of advantage.

    Science.gov (United States)

    Stephens, Christine

    2010-10-01

    There has been a great deal of social policy and health promotion practice directed toward the inclusion of underprivileged groups with the aim of improving their health. This focus on disadvantaged people and poor communities, to help them empower themselves and improve their lot, often fails because it ignores the role of the broader society. We neglect to note the crucial part that the advantaged play in perpetuating inequalities. Theory and empirical work from sociology and anthropology points to the everyday ways in which privileged people are able to maintain their advantage and even hi-jack the benefits of public health programmes designed to improve the health of the poor. Some examples from these other disciplines suggest ways in which a social psychological perspective can contribute to an understanding of how inequalities and poverty are perpetuated in everyday life. These understandings will inform the effectiveness of social programmes to reduce inequalities.

  20. Research on anisotropy of fusion-produced protons and neutrons emission from high-current plasma-focus discharges

    Energy Technology Data Exchange (ETDEWEB)

    Malinowski, K., E-mail: karol.malinowski@ncbj.gov.pl; Sadowski, M. J.; Szydlowski, A. [National Centre for Nuclear Research (NCBJ), 05-400 Otwock (Poland); Institute of Plasma Physics and Laser Microfusion (IFPiLM), 01-497 Warsaw (Poland); Skladnik-Sadowska, E.; Czaus, K.; Kwiatkowski, R.; Zaloga, D. [National Centre for Nuclear Research (NCBJ), 05-400 Otwock (Poland); Paduch, M.; Zielinska, E. [Institute of Plasma Physics and Laser Microfusion (IFPiLM), 01-497 Warsaw (Poland)

    2015-01-15

    The paper concerns fast protons and neutrons from D-D fusion reactions in a Plasma-Focus-1000U facility. Measurements were performed with nuclear-track detectors arranged in “sandwiches” of an Al-foil and two PM-355 detectors separated by a polyethylene-plate. The Al-foil eliminated all primary deuterons, but was penetrable for fast fusion protons. The foil and first PM-355 detector were penetrable for fast neutrons, which were converted into recoil-protons in the polyethylene and recorded in the second PM-355 detector. The “sandwiches” were irradiated by discharges of comparable neutron-yields. Analyses of etched tracks and computer simulations of the fusion-products behavior in the detectors were performed.

  1. Basic research on lattice structures focused on the reliance of the cross sectional area and additional coatings

    Directory of Open Access Journals (Sweden)

    Kessler Julia

    2017-01-01

    Full Text Available This scientific survey is about periodic lattice structures which are made by Selective Laser Melting (SLM. Selective laser melting is based on Additive Manufacturing. The increased use and increasing demand of lattice structures in different fields of applications forms the necessity of a closer look on complex structures. Lattice structures can be found in different fields of applications for example in lightweight applications, filters and heat exchangers. Because of the expanding of application areas and thus arising requirements, the quality improvement is indispensable. Additive manufacturing and especially the SLM process enable the manufacturing of highly complex shapes and structures. Further it allows the integration of lightweight structures within to be manufactured applications. These high performance structures and applications need specific boundary and process conditions [1-3]. The main aim of this survey is an extraction of important parameters concerning the shape of lattices. A first focus will be on mechanical properties and the therefore necessary tensile tests.

  2. Creating Learning Experiences that Promote Informal Science Education: Designing Conservation-Focused Interactive Zoo Exhibits through Action Research

    Science.gov (United States)

    Kalenda, Peter

    Research on exhibit design over the past twenty years has started to identify many different methods to increase the learning that occurs in informal education environments. This study utilized relevant research on exhibit design to create and study the effectiveness of a mobile interactive exhibit at the Seneca Park Zoo that promotes socialization, engagement in science, and conservation-related practices among guests. This study will serve as one component of a major redesign project at the Seneca Park Zoo for their Rocky Coasts exhibit. This action research study targeted the following question, "How can interactive exhibits be designed to promote socialization, engagement in science, and real-world conservation-related practices (RCPs) among zoo guests?" Specific research questions included: 1. In what ways did guests engage with the exhibit? 2. In what ways were guests impacted by the exhibit? a) What evidence exists, if any, of guests learning science content from the exhibit? b) What evidence exists, if any, of guests being emotionally affected by the exhibit? c) What evidence exists, if any, of guests changing their RCPs after visiting the exhibit? Data were collected through zoo guest surveys completed by zoo guests comparing multiple exhibits, interviews with guests before and after they used the prototype exhibit, observations and audio recordings of guests using the prototype exhibit, and follow-up phone interviews with guests who volunteered to participate. Data were analyzed collaboratively with members of the zoo's exhibit Redesign Team using grounded theory qualitative data analysis techniques to find patterns and trends among data. Initial findings from data analysis were used to develop shifts in the exhibit in order to increase visitor engagement and learning. This process continued for two full action research spirals, which resulted in three iterations of the prototype exhibit. The overall findings of this study highlight the ways in which

  3. A decade of research on health content in the media: the focus on health challenges and sociocultural context and attendant informational and ideological problems.

    Science.gov (United States)

    Kline, Kimberly N

    2006-01-01

    There is a burgeoning interest in the health and illness content of popular media in the domains of advertising, journalism, and entertainment. This article reviews the past 10 years of this research, describing the relationship between the health topics addressed in the research, the shifting focus of concerns about the media, and, ultimately, the variation in problems for health promotion. I suggest that research attending to topics related to bodily health challenges focused on whether popular media accurately or appropriately represented health challenges. The implication was that there is some consensus about more right or wrong, complete or incomplete ways of representing an issue; the problem was that the media are generally wrong. Alternatively, research addressing topics related to sociocultural context issues focused on how certain interests are privileged in the media. The implication was that competing groups are making claims on the system, but the problem was that popular media marginalizes certain interests. In short, popular media is not likely to facilitate understandings helpful to individuals coping with health challenges and is likely to perpetuate social and political power differentials with regard to health-related issues. I conclude by offering some possibilities for future health media content research.

  4. Research of principles for estimating the freshness of meat products by color analysis method

    Science.gov (United States)

    Gorbunova, Elena V.; Chertov, Aleksandr N.; Petukhova, Daria B.; Alekhin, Artem A.; Korotaev, Valery V.

    2015-03-01

    Color is one of the most important metrics of foodstuffs quality. It gives an indication of freshness, ingredient composition as well as about the presence or absence of falsification. Most often, the color is estimated visually, and thus, the evaluation is subjective. By automating the color analysis a wide application for this method could be found. The aim of this research is to study the principles of color analysis as applied to the task of evaluating the freshness of meat products using modern machine vision systems. From a scientific point of view, the color of meat depends on the proportion of myoglobin and its derivatives. It's the main pigment that characterizes the freshness of meat. Further color of meat can change due to oxidation of myoglobin during storage. Myoglobin exists in three forms. There are oxygenated form, oxidized form and form without oxygen. The meat color changes not only due to the conversion of one form into another. The content of amino acids and ammonia are another characteristics and constant signs of meat products spoilage. The paper presents the results of meat color computer simulation based on data on the content of various forms of myoglobin in different proportions. The spectral characteristic of the light source used to illuminate the meat sample is taken into account. Also the experimental studies were conducted using samples of beef. As a result the correlations between said biochemical indicators of the quality and color of the meat obtained with the help of machine vision system were found.

  5. Experimental estimation of moderator temperature coefficient of reactivity of the IPEN/MB-01 research reactor

    International Nuclear Information System (INIS)

    Silva, Rubens C. da; Bitelli, Ulysses D.; Mura, Luiz Ernesto C.

    2017-01-01

    The aim of this article is to present the procedure for the experimental estimation of the Moderator Temperature Coefficient of Reactivity of the IPEN/MB-01 Research Reactor, a parameter that has an important role in the physics and the control operations of any reactor facility. At the experiment, the IPEN/MB-01 reactor went critical at the power of 1W (1% of its total power), and whose core configuration was 28 x 26 rectangular array of UO_2 fuel rods, inside a light water (moderator) tank. In addition, there was a heavy water (D_2O) reflector installed in the West side of the core to obtain an adequate neutron reflection along the experiment. The moderator temperature was increased in steps of 4 °C, and the measurement of the mean moderator temperature was acquired using twelve calibrated thermocouples, placed around the reactor core. As a result, the mean value of -4.81 pcm/°C was obtained for such coefficient. The curves of ρ(T) (Reactivity x Temperature) and α"M_T(T)(Moderator Temperature Coefficient of Reactivity x Temperature) were developed using data from an experimental measurement of the integral reactivity curves through the Stable Period and Inverse Kinetics Methods, that was carried out at the reactor with the same core configuration. Such curves were compared and showed a very similar behavior between them. (author)

  6. Wanted: studies on mortality estimation methods for humanitarian emergencies, suggestions for future research

    Directory of Open Access Journals (Sweden)

    2007-06-01

    Full Text Available Abstract Measuring rates and circumstances of population mortality (in particular crude and under-5 year mortality rates is essential to evidence-based humanitarian relief interventions. Because prospective vital event registration is absent or deteriorates in nearly all crisis-affected populations, retrospective household surveys are often used to estimate and describe patterns of mortality. Originally designed for measuring vaccination coverage, the two-stage cluster survey methodology is frequently employed to measure mortality retrospectively due to limited time and resources during humanitarian emergencies. The method tends to be followed without considering alternatives, and there is a need for expert advice to guide health workers measuring mortality in the field. In a workshop in France in June 2006, we deliberated the problems inherent in this method when applied to measure outcomes other than vaccine coverage and acute malnutrition (specifically, mortality, and considered recommendations for improvement. Here we describe these recommendations and outline outstanding issues in three main problem areas in emergency mortality assessment discussed during the workshop: sampling, household data collection issues, and cause of death ascertainment. We urge greater research on these issues. As humanitarian emergencies become ever more complex, all agencies should benefit from the most recently tried and tested survey tools.

  7. Experimental estimation of moderator temperature coefficient of reactivity of the IPEN/MB-01 research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Rubens C. da; Bitelli, Ulysses D.; Mura, Luiz Ernesto C., E-mail: rubensrcs@usp.br, E-mail: ubitelli@ipen.br, E-mail: credidiomura@gmail.com [Universidade de Sao Paulo (PNV/POLI/USP), SP (Brazil). Arquitetura Naval e Departamento de Engenharia Oceanica; Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2017-07-01

    The aim of this article is to present the procedure for the experimental estimation of the Moderator Temperature Coefficient of Reactivity of the IPEN/MB-01 Research Reactor, a parameter that has an important role in the physics and the control operations of any reactor facility. At the experiment, the IPEN/MB-01 reactor went critical at the power of 1W (1% of its total power), and whose core configuration was 28 x 26 rectangular array of UO{sub 2} fuel rods, inside a light water (moderator) tank. In addition, there was a heavy water (D{sub 2}O) reflector installed in the West side of the core to obtain an adequate neutron reflection along the experiment. The moderator temperature was increased in steps of 4 °C, and the measurement of the mean moderator temperature was acquired using twelve calibrated thermocouples, placed around the reactor core. As a result, the mean value of -4.81 pcm/°C was obtained for such coefficient. The curves of ρ(T) (Reactivity x Temperature) and α{sup M}{sub T}(T)(Moderator Temperature Coefficient of Reactivity x Temperature) were developed using data from an experimental measurement of the integral reactivity curves through the Stable Period and Inverse Kinetics Methods, that was carried out at the reactor with the same core configuration. Such curves were compared and showed a very similar behavior between them. (author)

  8. Improved Monte Carlo - Perturbation Method For Estimation Of Control Rod Worths In A Research Reactor

    International Nuclear Information System (INIS)

    Kalcheva, Silva; Koonen, Edgar

    2008-01-01

    A hybrid method dedicated to improve the experimental technique for estimation of control rod worths in a research reactor is presented. The method uses a combination of Monte Carlo technique and perturbation theory. The perturbation theory is used to obtain the relation between the relative rod efficiency and the buckling of the reactor with partially inserted rod. A series of coefficients, describing the axial absorption profile are used to correct the buckling for an arbitrary composite rod, having complicated burn up irradiation history. These coefficients have to be determined - by experiment or by using some theoretical/numerical method. In the present paper they are derived from the macroscopic absorption cross sections, obtained from detailed Monte Carlo calculations by MCNPX 2.6.F of the axial burn up profile during control rod life. The method is validated on measurements of control rod worths at the BR2 reactor. Comparison with direct Monte Carlo evaluations of control rod worths is also presented. The uncertainties, arising from the used approximations in the presented hybrid method are discussed. (authors)

  9. Final report on the project research 'stochastic effects of irradiation and risk estimation'

    International Nuclear Information System (INIS)

    1989-03-01

    The title project research was carried out through 1983-1987, by three groups for the studies of radiation carcinogenesis, human genetic effects, and radiotoxicology. 8 reports by the first group, 3 by the second, and 6 by the third group are collected in this issue. The contents are as follows. Serial sacrifice study on tumorigenesis in male C57BL/6J mice exposed to gamma-ray or fast neutron radiation; Influence of biological variables on radiation carcinogenesis; Studies on radiation-induced thymic lymphomagenesis; Modifying factors of radiation induced myeloid leukemia of C3H/He mouse; Cell kinetic studies on radiation induced leukemogenesis; Cytogenetical studies on the mechanism of radiation induced neoplasmas; Molecular biological study on genetic stability of the genome; Protein factors regulating proliferation and differentiation of normal and neoplastic cells; Studies on dose-radiation relationships for induction of chromosome abberations in stem-spermatogonia of three crab-eating monkey after low and high dose rate γ-irradiation; Risk estimation of radiation mutagenesis in man by using cultured mammalian cells; Effects of ionizing radiation on male germ cells of crabeating monkey; Movement and metabolism of radioactive particles in the respiratory tract; Studies on dosimetry for internally deposited alpha-emitters; Comparative toxicological studies on the effects of internal exposures; Studies on treatment of alpha-radioactive wastes; Methodological studies on the inhalation of radioactive aerosols; Removal of transuranic elements by DTPA. (A. Y.)

  10. 137Cs use in estimating soil erosion: 30 years of research

    International Nuclear Information System (INIS)

    Ritchie, J.C.

    1998-01-01

    Significant amounts of fallout 137 Cs from nuclear weapons tests were introduced to the landscape during the 1950s and 1960s. Once 137 Cs reaches the soil surface it is strongly and quickly adsorbed by clay particles, and is essentially nonexchangeable in most environments. Thus, 137 Cs becomes and effective tracer of the movement of soil particles across the landscape. Over the past 30 years, researchers have shown that 137 Cs can be used to study soil movement. Early work used empirical relationships between soil loss and 137 Cs loss to estimate erosion. This was followed by the development of proportional and theoretical models to relate 137 Cs movement and soil redistribution. Most of the problems related to the 137 Cs technique are the same as those encountered with other techniques (i.e., sampling, measurement). The 137 Cs technique can make actual measurements of soil loss and redeposition in fields, fostering the formulation of better plans to conserve the quality of the landscape. This paper reviews the development of the 137 Cs technique to show how it can be used to understand erosion and soil movement on the landscape. (author)

  11. Toward an integrative understanding of narrative and emotion processes in Emotion-focused therapy of depression: implications for theory, research and practice.

    Science.gov (United States)

    Angus, Lynne

    2012-01-01

    This paper addresses the fundamental contributions of client narrative disclosure in psychotherapy and its importance for the elaboration of new emotional meanings and self understanding in the context of Emotion-focused therapy (EFT) of depression. An overview of the multi-methodological steps undertaken to empirically investigate the contributions of client story telling, emotional differentiation and meaning-making processes (Narrative Processes Coding System; Angus et al., 1999) in EFT treatments of depression is provided, followed by a summary of key research findings that informed the development of a narrative-informed approach to Emotion-focused therapy of depression (Angus & Greenberg, 2011). Finally, the clinical practice and training implications of adopting a research-informed approach to working with narrative and emotion processes in EFT are described, and future research directions discussed.

  12. A Bayesian approach for estimating under-reported dengue incidence with a focus on non-linear associations between climate and dengue in Dhaka, Bangladesh.

    Science.gov (United States)

    Sharmin, Sifat; Glass, Kathryn; Viennet, Elvina; Harley, David

    2018-04-01

    Determining the relation between climate and dengue incidence is challenging due to under-reporting of disease and consequent biased incidence estimates. Non-linear associations between climate and incidence compound this. Here, we introduce a modelling framework to estimate dengue incidence from passive surveillance data while incorporating non-linear climate effects. We estimated the true number of cases per month using a Bayesian generalised linear model, developed in stages to adjust for under-reporting. A semi-parametric thin-plate spline approach was used to quantify non-linear climate effects. The approach was applied to data collected from the national dengue surveillance system of Bangladesh. The model estimated that only 2.8% (95% credible interval 2.7-2.8) of all cases in the capital Dhaka were reported through passive case reporting. The optimal mean monthly temperature for dengue transmission is 29℃ and average monthly rainfall above 15 mm decreases transmission. Our approach provides an estimate of true incidence and an understanding of the effects of temperature and rainfall on dengue transmission in Dhaka, Bangladesh.

  13. Highly cited German research contributions to the fields of radiation oncology, biology, and physics. Focus on collaboration and diversity

    Energy Technology Data Exchange (ETDEWEB)

    Nieder, C. [Nordland Hospital, Bodoe (Norway). Dept. of Oncology and Palliative Medicine; Tromsoe Univ. (Norway). Inst. of Clinical Medicine

    2012-10-15

    Background and purpose: Tight budgets and increasing competition for research funding pose challenges for highly specialized medical disciplines such as radiation oncology. Therefore, a systematic review was performed of successfully completed research that had a high impact on clinical practice. These data might be helpful when preparing new projects. Methods: Different measures of impact, visibility, and quality of published research are available, each with its own pros and cons. For this study, the article citation rate was chosen (minimum 15 citations per year on average). Highly cited German contributions to the fields of radiation oncology, biology, and physics (published between 1990 and 2010) were identified from the Scopus database. Results: Between 1990 and 2010, 106 articles published in 44 scientific journals met the citation requirement. The median average of yearly citations was 21 (maximum 167, minimum 15). All articles with {>=} 40 citations per year were published between 2003 and 2009, consistent with the assumption that the citation rate gradually increases for up to 2 years after publication. Most citations per year were recorded for meta-analyses and randomized phase III trials, which typically were performed by collaborative groups. Conclusion: A large variety of clinical radiotherapy, biology, and physics topics achieved high numbers of citations. However, areas such as quality of life and side effects, palliative radiotherapy, and radiotherapy for nonmalignant disorders were underrepresented. Efforts to increase their visibility might be warranted. (orig.)

  14. Highly cited German research contributions to the fields of radiation oncology, biology, and physics. Focus on collaboration and diversity

    International Nuclear Information System (INIS)

    Nieder, C.; Tromsoe Univ.

    2012-01-01

    Background and purpose: Tight budgets and increasing competition for research funding pose challenges for highly specialized medical disciplines such as radiation oncology. Therefore, a systematic review was performed of successfully completed research that had a high impact on clinical practice. These data might be helpful when preparing new projects. Methods: Different measures of impact, visibility, and quality of published research are available, each with its own pros and cons. For this study, the article citation rate was chosen (minimum 15 citations per year on average). Highly cited German contributions to the fields of radiation oncology, biology, and physics (published between 1990 and 2010) were identified from the Scopus database. Results: Between 1990 and 2010, 106 articles published in 44 scientific journals met the citation requirement. The median average of yearly citations was 21 (maximum 167, minimum 15). All articles with ≥ 40 citations per year were published between 2003 and 2009, consistent with the assumption that the citation rate gradually increases for up to 2 years after publication. Most citations per year were recorded for meta-analyses and randomized phase III trials, which typically were performed by collaborative groups. Conclusion: A large variety of clinical radiotherapy, biology, and physics topics achieved high numbers of citations. However, areas such as quality of life and side effects, palliative radiotherapy, and radiotherapy for nonmalignant disorders were underrepresented. Efforts to increase their visibility might be warranted. (orig.)

  15. Doing Institutional Research: A Focus on Professional Development. Papers from the Annual Meeting of the North East Association for Institutional Research (9th, Durham, New Hampshire, October 17-19, 1982).

    Science.gov (United States)

    Green, Diana M., Ed.

    Institutional research that focuses on professional development is addressed in 35 papers from the 1982 meeting of the North East Association for Institutional Research. Titles and authors include the following: "Modeling College Student Adjustment and Retention for the Individual Institution" (Norman D. Aitken); "The Development Saga of an…

  16. Elsevier Trophoblast Research Award lecture: Molecular mechanisms underlying estrogen functions in trophoblastic cells--focus on leptin expression.

    Science.gov (United States)

    Gambino, Y P; Maymó, J L; Pérez Pérez, A; Calvo, J C; Sánchez-Margalet, V; Varone, C L

    2012-02-01

    The steroid hormone 17β-estradiol is an estrogen that influences multiple aspects of placental function and fetal development in humans. During early pregnancy it plays a role in the regulation of blastocyst implantation, trophoblast differentiation and invasiveness, remodeling of uterine arteries, immunology and trophoblast production of hormones such as leptin. Estradiol exerts some effects through the action of classical estrogen receptors ERα and ERβ, which act as ligand-activated transcription factors and regulate gene expression. In addition, estradiol can elicit rapid responses from membrane-associated receptors, like activation of protein-kinase pathways. Thus, the cellular effects of estradiol will depend on the specific receptors expressed and the integration of their signaling events. Leptin, the 16,000MW protein product of the obese gene, was originally considered an adipocyte-derived signaling molecule for the central control of metabolism. However, pleiotropic effects of leptin have been identified in reproduction and pregnancy. The leptin gene is expressed in placenta, where leptin promotes proliferation and survival of trophoblastic cells. Expression of leptin in placenta is highly regulated by key pregnancy molecules as hCG and estradiol. The aim of this paper is to review the molecular mechanisms underlying estrogen functions in trophoblastic cells; focusing on mechanisms involved in estradiol regulation of placental leptin expression. Copyright © 2012 Elsevier Ltd. All rights reserved.

  17. Theoretical Research on Thermal Shock Resistance of Ultra-High Temperature Ceramics Focusing on the Adjustment of Stress Reduction Factor

    Directory of Open Access Journals (Sweden)

    Daining Fang

    2013-02-01

    Full Text Available The thermal shock resistance of ceramics depends on not only the mechanical and thermal properties of materials, but also the external constraint and thermal condition. So, in order to study the actual situation in its service process, a temperature-dependent thermal shock resistance model for ultra-high temperature ceramics considering the effects of the thermal environment and external constraint was established based on the existing theory. The present work mainly focused on the adjustment of the stress reduction factor according to different thermal shock situations. The influences of external constraint on both critical rupture temperature difference and the second thermal shock resistance parameter in either case of rapid heating or cooling conditions had been studied based on this model. The results show the necessity of adjustment of the stress reduction factor in different thermal shock situations and the limitations of the applicable range of the second thermal shock resistance parameter. Furthermore, the model was validated by the finite element method.

  18. Using customer-focused research and design to build a self-service online store: a case study

    Directory of Open Access Journals (Sweden)

    Ahmadi MB

    2013-02-01

    Full Text Available Michael B Ahmadi,1 William Trefzger,2 Rich Morey,1 Ileana Quintas31Substance Abuse and Mental Health Services Administration, Rockville, 2Centers for Medicare and Medicaid Services, Baltimore, 3IQ Solutions, Inc, Rockville, MD, USAAbstract: American government information centers need to be responsive to an increasingly customer driven information environment while ensuring the sustainability of operations. Enhanced self-service options offer one avenue for addressing both of these needs. This article presents a case study of how the US Substance Abuse and Mental Health Services Administration used extensive stakeholder research and a customer-centric design to reframe its service model by building a self-service online store that integrates access to more than 1300 behavioral health publications previously housed in two separate clearinghouses. The redesigned Substance Abuse and Mental Health Services Administration Store offers users a modern e-commerce website that not only helps customers find, order, download, and share products, but also encourages serendipitous content exploration, which has led to increased orders containing both substance abuse and mental health publications.Keywords: customer research, taxonomy, usability testing, web analytics, web design

  19. Fund my treatment!: A call for ethics-focused social science research into the use of crowdfunding for medical care.

    Science.gov (United States)

    Snyder, Jeremy; Mathers, Annalise; Crooks, Valorie A

    2016-11-01

    Crowdfunding involves raising money from large groups of individuals, often through the use of websites dedicated to this purpose. Crowdfunding campaigns aimed at raising money to pay for expenses related to receiving medical treatment are receiving increased media attention and there is evidence that medical crowdfunding websites are heavily used. Nonetheless, virtually no scholarly attention has been paid to these medical crowdfunding campaigns and there is no systematic evidence about how widely they are used and for what reasons, and what effects they have on the provision of medical care and individuals' relationships to their health systems. Ethical concerns have been raised in relation to these campaigns, focusing on issues for campaigners and donors such as exposure to fraudulent campaigns, loss of privacy, and fairness in how medical crowdfunding funds are distributed. Medical crowdfunding websites themselves have not been systematically studied, despite their significant influence on how these campaigns are developed and promoted. In this paper, we identify three very broad and pressing ethical questions regarding medical crowdfunding for social scientists to address and offer some preliminary insights into key issues informing future answers to each: Who benefits the most from medical crowdfunding and how does medical crowdfunding affect access to medical care; How does medical crowdfunding affect our understanding of the causes of inadequate access to medical care; and How are campaigner and donor privacy affected by website design? Our observations indicate the need for increased scholarly attention to the ethical and practical effects of medical crowdfunding for campaigners, recipients, donors, and the health system as a whole. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Research on State-of-Charge (SOC) estimation using current integration based on temperature compensation

    Science.gov (United States)

    Yin, J.; Shen, Y.; Liu, X. T.; Zeng, G. J.; Liu, D. C.

    2017-11-01

    The traditional current integral method for the state-of-charge (SOC) estimation has an unusable estimation accuracy because of the current measuring error. This paper proposed a closed-loop temperature compensation method to improve the SOC estimation accuracy of current integral method by eliminating temperature drift. Through circuit simulation result in Multisim, the stability of current measuring accuracy is improved by more than 10 times. In a designed 70 charge-discharge experimental circle, the SOC estimation error with temperature compensation had 30 times less than error in normal situation without compensation.

  1. A survey of the state-of-the-art and focused research in range systems, task 1

    Science.gov (United States)

    Omura, J. K.

    1986-07-01

    This final report presents the latest research activity in voice compression. We have designed a non-real time simulation system that is implemented around the IBM-PC where the IBM-PC is used as a speech work station for data acquisition and analysis of voice samples. A real-time implementation is also proposed. This real-time Voice Compression Board (VCB) is built around the Texas Instruments TMS-3220. The voice compression algorithm investigated here was described in an earlier report titled, Low Cost Voice Compression for Mobile Digital Radios, by the author. We will assume the reader is familiar with the voice compression algorithm discussed in this report. The VCB compresses speech waveforms at data rates ranging from 4.8 K bps to 16 K bps. This board interfaces to the IBM-PC 8-bit bus, and plugs into a single expansion slot on the mother board.

  2. Assessment of Soft Power Strategies: Towards an Aggregative Analytical Model for Country-Focused Case Study Research

    Directory of Open Access Journals (Sweden)

    Patalakh Artem

    2016-10-01

    Full Text Available The paper advances a realist analytical model for case studies of national soft power policies. First, it argues that for the purposes of realist analysis, a soft power policy must be considered as a rational strategy pursued under the conditions of competition. Furthermore, it emphasises the importance of taking into account the specificities of the recipient state as well as the fact that a soft power strategy is targeted at both its elite and its public. In addition, the article substantiates the necessity to draw a clear-cut distinction between soft power sources and instruments and shows possible shortcomings that research can have should this distinction fail to be made. Finally, the paper discusses the impact of a competitor’s presence on a soft power strategy and specifies the terms under which disregarding this impact may engender a wrong conclusion.

  3. Cost estimation: An expert-opinion approach. [cost analysis of research projects using the Delphi method (forecasting)

    Science.gov (United States)

    Buffalano, C.; Fogleman, S.; Gielecki, M.

    1976-01-01

    A methodology is outlined which can be used to estimate the costs of research and development projects. The approach uses the Delphi technique a method developed by the Rand Corporation for systematically eliciting and evaluating group judgments in an objective manner. The use of the Delphi allows for the integration of expert opinion into the cost-estimating process in a consistent and rigorous fashion. This approach can also signal potential cost-problem areas. This result can be a useful tool in planning additional cost analysis or in estimating contingency funds. A Monte Carlo approach is also examined.

  4. Meteorological Research Institute multivariate ocean variational estimation (MOVE) system: Some early results

    Science.gov (United States)

    Usui, Norihisa; Ishizaki, Shiro; Fujii, Yosuke; Tsujino, Hiroyuki; Yasuda, Tamaki; Kamachi, Masafumi

    The Meteorological Research Institute multivariate ocean variational estimation (MOVE) System has been developed as the next-generation ocean data assimilation system in Japan Meteorological Agency. A multivariate three-dimensional variational (3DVAR) analysis scheme with vertical coupled temperature salinity empirical orthogonal function modes is adopted. The MOVE system has two varieties, the global (MOVE-G) and North Pacific (MOVE-NP) systems. The equatorial Pacific and western North Pacific are analyzed with assimilation experiments using MOVE-G and -NP, respectively. In each system, the salinity and velocity fields are well reproduced, even in cases without salinity data. Changes in surface and subsurface zonal currents during the 1997/98 El Niño event are captured well, and their transports are reasonably consistent with in situ observations. For example, the eastward transport in the upper layer around the equator has 70 Sv in spring 1997 and weakens in spring 1998. With MOVE-NP, the Kuroshio transport has 25 Sv in the East China Sea, and 40 Sv crossing the ASUKA (Affiliated Surveys of the Kuroshio off Cape Ashizuri) line south of Japan. The variations in the Kuroshio transports crossing the ASUKA line agree well with observations. The Ryukyu Current System has a transport ranging from 6 Sv east of Taiwan to 17 Sv east of Amami. The Oyashio transport crossing the OICE (Oyashio Intensive observation line off Cape Erimo) line south of Hokkaido has 14 Sv southwestward (near shore) and 11 Sv northeastward (offshore). In the Kuroshio Oyashio transition area east of Japan, the eastward transport has 41 Sv (32 36°N) and 12 Sv (36 39°N) crossing the 145°E line.

  5. Bias Correction for the Maximum Likelihood Estimate of Ability. Research Report. ETS RR-05-15

    Science.gov (United States)

    Zhang, Jinming

    2005-01-01

    Lord's bias function and the weighted likelihood estimation method are effective in reducing the bias of the maximum likelihood estimate of an examinee's ability under the assumption that the true item parameters are known. This paper presents simulation studies to determine the effectiveness of these two methods in reducing the bias when the item…

  6. Focus group discussions

    CERN Document Server

    Hennink, Monique M

    2014-01-01

    The Understanding Research series focuses on the process of writing up social research. The series is broken down into three categories: Understanding Statistics, Understanding Measurement, and Understanding Qualitative Research. The books provide researchers with guides to understanding, writing, and evaluating social research. Each volume demonstrates how research should be represented, including how to write up the methodology as well as the research findings. Each volume also reviews how to appropriately evaluate published research. Focus Group Discussions addresses the challenges associated with conducting and writing focus group research. It provides detailed guidance on the practical and theoretical considerations in conducting focus group discussions including: designing the discussion guide, recruiting participants, training a field team, moderating techniques and ethical considerations. Monique Hennink describes how a methodology section is read and evaluated by others, such as journal reviewers or ...

  7. Research

    African Journals Online (AJOL)

    Research. December 2017, Vol. 9, No. 4 AJHPE 171. During curriculum development, teachers ... Ideally, examiners need an educational method to determine ..... A major focus of this study was addressing the human resource gap when.

  8. Acquisition of a Multi-Domain Advanced Real-Time Simulator to Support DoD-focused Interdisciplinary Research at CSUB

    Science.gov (United States)

    2017-10-17

    SECURITY CLASSIFICATION OF: 1. REPORT DATE (DD-MM-YYYY) 4. TITLE AND SUBTITLE 13. SUPPLEMENTARY NOTES 12. DISTRIBUTION AVAILIBILITY STATEMENT 6...0704-0188 3. DATES COVERED (From - To) - Approved for public release; distribution is unlimited. UU UU UU UU 17-10-2017 25-Jul-2016 24-Jul-2017 Final...Report: Acquisition of a Multi-Domain Advanced Real- Time Simulator to Support DoD-focused Interdisciplinary Research at CSUB The views, opinions and

  9. A Design-Based Research Project on Information Literacy Focusing on Process, Reflections and Self-Feedback

    Directory of Open Access Journals (Sweden)

    Majbritt Ursula Johansen

    2016-12-01

    Full Text Available Many curriculums assume that the new generation of students are digital natives and information literate. However, studies show that this is not often the case. From these studies and our own experiences working with multidisciplinary students in the Health Sciences we found that students were not as information literate as required in the curriculum. Using Design Based Research as a method (following the four phases below, we developed a new information search process and a web-based tool with feedback opportunities from teachers and librarians in order to qualify the students competencies. Problem identification: Despite earlier initiatives from library and department, the students didn’t achieve higher levels of information literacy. Prototyping: Requirements and educational material were merged and tested while gathering feedback. Iterations: The prototype and feedback were evaluated and developed into a new information search process, which was tested and evaluated. Reflection and generalization: Initiative was taken to develope a web-based application visualizing the steps with the learning points: self-feedback, peer-feedback and counselor feedback. The result of the project is a new information search process model and a web-based learning environment called B!NKO 2.0. The evaluations have shown positive feedback on both the process and the web tool. The project has opened up new possibilities that go beyond the Health multidisciplinary students. A new project concerning the Humanities and Social Sciences is incipient. In this project new functionalities are also expected. B!NKO 2.0 has to a great extent shown its worth to help Health multidisciplinary students to get a deeper understanding of information literacy, and how to develop and change searches to get better results. B!NKO 2.0 has also given a positive "side effect” on the librarians work. Time spend on the "Book a Librarian” service have decreased for the librarians using

  10. Age estimates for the buckwheat family Polygonaceae based on sequence data calibrated by fossils and with a focus on the amphi-Pacific Muehlenbeckia.

    Directory of Open Access Journals (Sweden)

    Tanja M Schuster

    Full Text Available The buckwheat family Polygonaceae is a diverse group of plants and is a good model for investigating biogeography, breeding systems, coevolution with symbionts such as ants and fungi, functional trait evolution, hybridization, invasiveness, morphological plasticity, pollen morphology and wood anatomy. The main goal of this study was to obtain age estimates for Polygonaceae by calibrating a Bayesian phylogenetic analysis, using a relaxed molecular clock with fossil data. Based on the age estimates, we also develop hypotheses about the historical biogeography of the Southern Hemisphere group Muehlenbeckia. We are interested in addressing whether vicariance or dispersal could account for the diversification of Muehlenbeckia, which has a "Gondwanan" distribution. Eighty-one species of Polygonaceae were analysed with MrBayes to infer species relationships. One nuclear (nrITS and three chloroplast markers (the trnL-trnF spacer region, matK and ndhF genes were used. The molecular data were also analysed with Beast to estimate divergence times. Seven calibration points including fossil pollen and a leaf fossil of Muehlenbeckia were used to infer node ages. Results of the Beast analyses indicate an age of 110.9 (exponential/lognormal priors/118.7 (uniform priors million years (Myr with an uncertainty interval of (90.7-125.0 Myr for the stem age of Polygonaceae. This age is older than previously thought (Maastrichtian, approximately 65.5-70.6 Myr. The estimated divergence time for Muehlenbeckia is 41.0/41.6 (39.6-47.8 Myr and its crown clade is 20.5/22.3 (14.2-33.5 Myr old. Because the breakup of Gondwana occurred from 95-30 Myr ago, diversification of Muehlenbeckia is best explained by oceanic long-distance and maybe stepping-stone dispersal rather than vicariance. This study is the first to give age estimates for clades of Polygonaceae and functions as a jumping-off point for future studies on the historical biogeography of the family.

  11. The relevance of preclinical research models for the development of antimigraine drugs: Focus on 5-HT1B/1D and CGRP receptors

    DEFF Research Database (Denmark)

    Gupta, S.; Villalon, C.M.

    2010-01-01

    to the relief of migraineurs. Pathophysiological factors culminating into migraine headaches have not yet been completely deciphered and, thus, pose an additional challenge for preclinical research in the absence of any direct experimental marker. Migraine provocation experiments in humans use a head......-score to evaluate migraine, as articulated by the volunteer, which cannot be applied to laboratory animals. Therefore, basic research focuses on different symptoms and putative mechanisms, one at a time or in combination, to validate the hypotheses. Studies in several species, utilizing different preclinical...... incorporating the newer ideas/techniques in order to get better insights into migraine pathophysiology. (C) 2010 Elsevier Inc. All rights reserved...

  12. Are there differences between unconditional and conditional demand estimates? implications for future research and policy

    Directory of Open Access Journals (Sweden)

    Hidayat Budi

    2008-08-01

    Full Text Available Abstract Background Estimations of the demand for healthcare often rely on estimating the conditional probabilities of being ill. Such estimate poses several problems due to sample selectivity problems and an under-reporting of the incidence of illness. This study examines the effects of health insurance on healthcare demand in Indonesia, using samples that are both unconditional and conditional on being ill, and comparing the results. Methods The demand for outpatient care in three alternative providers was modeled using a multinomial logit regression for samples unconditional on being ill (N = 16485 and conditional on being ill (N = 5055. The ill sample was constructed from two measures of health status – activity of daily living impairments and severity of illness – derived from the second round of panel data from the Indonesian Family Life Survey. The recycling prediction method was used to predict the distribution of utilization rates based on having health insurance and income status, while holding all other variables constant. Results Both unconditional and conditional estimates yield similar results in terms of the direction of the most covariates. The magnitude effects of insurance on healthcare demand are about 7.5% (public providers and 20% (private providers higher for unconditional estimates than for conditional ones. Further, exogenous variables in the former estimates explain a higher variation of the model than that in the latter ones. Findings confirm that health insurance has a positive impact on the demand for healthcare, with the highest effect found among the lowest income group. Conclusion Conditional estimates do not suffer from statistical selection bias. Such estimates produce smaller demand effects for health insurance than unconditional ones do. Whether to rely on conditional or unconditional demand estimates depends on the purpose of study in question. Findings also demonstrate that health insurance programs

  13. Research on Modified Root-MUSIC Algorithm of DOA Estimation Based on Covariance Matrix Reconstruction

    Directory of Open Access Journals (Sweden)

    Changgan SHU

    2014-09-01

    Full Text Available In the standard root multiple signal classification algorithm, the performance of direction of arrival estimation will reduce and even lose effect in circumstances that a low signal noise ratio and a small signals interval. By reconstructing and weighting the covariance matrix of received signal, the modified algorithm can provide more accurate estimation results. The computer simulation and performance analysis are given next, which show that under the condition of lower signal noise ratio and stronger correlation between signals, the proposed modified algorithm could provide preferable azimuth estimating performance than the standard method.

  14. Research on the Method of Noise Error Estimation of Atomic Clocks

    Science.gov (United States)

    Song, H. J.; Dong, S. W.; Li, W.; Zhang, J. H.; Jing, Y. J.

    2017-05-01

    The simulation methods of different noises of atomic clocks are given. The frequency flicker noise of atomic clock is studied by using the Markov process theory. The method for estimating the maximum interval error of the frequency white noise is studied by using the Wiener process theory. Based on the operation of 9 cesium atomic clocks in the time frequency reference laboratory of NTSC (National Time Service Center), the noise coefficients of the power-law spectrum model are estimated, and the simulations are carried out according to the noise models. Finally, the maximum interval error estimates of the frequency white noises generated by the 9 cesium atomic clocks have been acquired.

  15. Research

    African Journals Online (AJOL)

    abp

    2015-08-31

    Aug 31, 2015 ... 2. Introduction. Recent estimates show that the overall ante-natal care (ANC) ... important milestones required to achieve optimum maternal and child health. ... 15-49 years. The survey was conducted by the National Population .... means univariate analyses to determine the odds of utilization of focused ...

  16. Gender- and sex-specific sports-related injury research in emergency medicine: a consensus on future research direction and focused application.

    Science.gov (United States)

    Raukar, Neha P; Zonfrillo, Mark R; Kane, Kathleen; Davenport, Moira; Espinoza, Tamara R; Weiland, Jessica; Franco, Vanessa; Vaca, Federico E

    2014-12-01

    Title IX, the commercialization of sports, the social change in sports participation, and the response to the obesity epidemic have contributed to the rapid proliferation of participation in both competitive organized sports and nontraditional athletic events. As a consequence, emergency physicians are regularly involved in the acute diagnosis, management, disposition, and counseling of a broad range of sports-related pathology. Three important and highly publicized mechanisms of injury in sports relevant to emergency medicine (EM) include concussion, heat illness, and sudden cardiac death. In conjunction with the 2014 Academic Emergency Medicine consensus conference "Gender-specific Research in Emergency Care: Investigate, Understand, and Translate How Gender Affects Patient Outcomes," a consensus group consisting of experts in EM, emergency neurology, sports medicine, and public health convened to deliberate and develop research questions that could ultimately advance the field of sports medicine and allow for meaningful application in the emergency department (ED) clinical setting. Sex differences in injury risk, diagnosis, ED treatment, and counseling are identified in each of these themes. This article presents the consensus-based priority research agenda. © 2014 by the Society for Academic Emergency Medicine.

  17. DOTD support for UTC project : travel time estimation using bluetooth, [research project capsule].

    Science.gov (United States)

    2013-10-01

    Travel time estimates are useful tools for measuring congestion in an urban area. Current : practice involves using probe vehicles or video cameras to measure travel time, but this is a laborintensive and expensive means of obtaining the information....

  18. [Research Progress of Carrion-breeding Phorid Flies for Post-mortem Interval Estimation in Forensic Medicine].

    Science.gov (United States)

    Li, L; Feng, D X; Wu, J

    2016-10-01

    It is a difficult problem of forensic medicine to accurately estimate the post-mortem interval. Entomological approach has been regarded as an effective way to estimate the post-mortem interval. The developmental biology of carrion-breeding flies has an important position at the post-mortem interval estimation. Phorid flies are tiny and occur as the main or even the only insect evidence in relatively enclosed environments. This paper reviews the research progress of carrion-breeding phorid flies for estimating post-mortem interval in forensic medicine which includes their roles, species identification and age determination of immatures. Copyright© by the Editorial Department of Journal of Forensic Medicine.

  19. A bibliometric review of drug and alcohol research focused on Indigenous peoples of Australia, New Zealand, Canada and the United States.

    Science.gov (United States)

    Clifford, Anton; Shakeshaft, Anthony

    2017-07-01

    Indigenous peoples of Australia, New Zealand, Canada and the United States experience a disproportionately high burden of harms from substance misuse. Research is therefore required to improve our understanding of substance use in Indigenous populations and provide evidence on strategies effective for reducing harmful use. A search of 13 electronic databases for peer-reviewed articles published between 1993 and 2014 focusing on substance use and Indigenous peoples of Australia, New Zealand, Canada and the United States. Relevant abstracts were classified as data or non-data based research. Data-based studies were further classified as measurement, descriptive or intervention and their trends examined by country and drug type. Intervention studies were classified by type and their evaluation designs classified using the Cochrane Effective Practice and Organisation of Care (EPOC) data collection checklist. There was a statistically significant increase from 1993 to 2014 in the percentage of total publications that were data-based (P Indigenous drug and alcohol field are required. The dominance of descriptive research in the Indigenous drug and alcohol field is less than optimal for generating evidence to inform Indigenous drug and alcohol policy and programs. [Clifford A, Shakeshaft A. A bibliometric review of drug and alcohol research focused on Indigenous peoples of Australia, New Zealand, Canada and the United States. Drug Alcohol Rev 2017;36:509-522]. © 2017 Australasian Professional Society on Alcohol and other Drugs.

  20. Research on bathymetry estimation by Worldview-2 based with the semi-analytical model

    Science.gov (United States)

    Sheng, L.; Bai, J.; Zhou, G.-W.; Zhao, Y.; Li, Y.-C.

    2015-04-01

    South Sea Islands of China are far away from the mainland, the reefs takes more than 95% of south sea, and most reefs scatter over interested dispute sensitive area. Thus, the methods of obtaining the reefs bathymetry accurately are urgent to be developed. Common used method, including sonar, airborne laser and remote sensing estimation, are limited by the long distance, large area and sensitive location. Remote sensing data provides an effective way for bathymetry estimation without touching over large area, by the relationship between spectrum information and bathymetry. Aimed at the water quality of the south sea of China, our paper develops a bathymetry estimation method without measured water depth. Firstly the semi-analytical optimization model of the theoretical interpretation models has been studied based on the genetic algorithm to optimize the model. Meanwhile, OpenMP parallel computing algorithm has been introduced to greatly increase the speed of the semi-analytical optimization model. One island of south sea in China is selected as our study area, the measured water depth are used to evaluate the accuracy of bathymetry estimation from Worldview-2 multispectral images. The results show that: the semi-analytical optimization model based on genetic algorithm has good results in our study area;the accuracy of estimated bathymetry in the 0-20 meters shallow water area is accepted.Semi-analytical optimization model based on genetic algorithm solves the problem of the bathymetry estimation without water depth measurement. Generally, our paper provides a new bathymetry estimation method for the sensitive reefs far away from mainland.

  1. Authentic Leadership, Research Integrity, and Institutions of Higher Learning: Why Focusing on Departmental Leadership is Critical for Preserving the Sanctity of Science

    Science.gov (United States)

    Echols, Katherine I.

    One of the most overlooked and complex problems that universities and colleges face nation-wide is how to reduce and eliminate research misconduct. Because of the confidential nature of allegations of research misconduct and the high rate of underreporting, administrators at scholarly institutions struggle with understanding the cause of such behavior. Without a clear picture of the prevalence of misconduct or the barriers to reporting, leaders at institutions of higher learning find themselves at a disadvantage when dealing with these problems. This uncertainty coupled with a growing regulatory emphasis from federal funding agencies, results in a reactionary approach while questionable practices go unchecked. In the early 2000s, federal funding agencies began requiring colleges and universities to provide training in the responsible conduct of research prior to receiving funding. The Responsible Conduct of Research (RCR) training covers research misconduct (falsification of data, fabricating data, and plagiarism) as well as other topics related to research misbehaviors (mentoring, peer review, data management, authorship, etc). This emphasis on training, while well intended, has not had a significant impact on faculty and student knowledge about misconduct. Authentic Leadership Theory is based on Aristotle's concept of authenticity and has gained attention over the last decade. It is comprised of four main components: Balanced processing, internalized moral perspective, relational transparency, and self-awareness. These types of leaders focus on moral standards and values and that is what guides his or her leadership. This study evaluates the impact authentic leaders have on shaping the ethical attitudes of faculty when they are placed in direct departmental supervisory positions. A survey of faculty from 15 Mississippi colleges and universities was conducted. Results indicate that the self-awareness and relational transparency constructs of authentic leadership

  2. Conditional random slope: A new approach for estimating individual child growth velocity in epidemiological research.

    Science.gov (United States)

    Leung, Michael; Bassani, Diego G; Racine-Poon, Amy; Goldenberg, Anna; Ali, Syed Asad; Kang, Gagandeep; Premkumar, Prasanna S; Roth, Daniel E

    2017-09-10

    Conditioning child growth measures on baseline accounts for regression to the mean (RTM). Here, we present the "conditional random slope" (CRS) model, based on a linear-mixed effects model that incorporates a baseline-time interaction term that can accommodate multiple data points for a child while also directly accounting for RTM. In two birth cohorts, we applied five approaches to estimate child growth velocities from 0 to 12 months to assess the effect of increasing data density (number of measures per child) on the magnitude of RTM of unconditional estimates, and the correlation and concordance between the CRS and four alternative metrics. Further, we demonstrated the differential effect of the choice of velocity metric on the magnitude of the association between infant growth and stunting at 2 years. RTM was minimally attenuated by increasing data density for unconditional growth modeling approaches. CRS and classical conditional models gave nearly identical estimates with two measures per child. Compared to the CRS estimates, unconditional metrics had moderate correlation (r = 0.65-0.91), but poor agreement in the classification of infants with relatively slow growth (kappa = 0.38-0.78). Estimates of the velocity-stunting association were the same for CRS and classical conditional models but differed substantially between conditional versus unconditional metrics. The CRS can leverage the flexibility of linear mixed models while addressing RTM in longitudinal analyses. © 2017 The Authors American Journal of Human Biology Published by Wiley Periodicals, Inc.

  3. Research on Radar Micro-Doppler Feature Parameter Estimation of Propeller Aircraft

    Science.gov (United States)

    He, Zhihua; Tao, Feixiang; Duan, Jia; Luo, Jingsheng

    2018-01-01

    The micro-motion modulation effect of the rotated propellers to radar echo can be a steady feature for aircraft target recognition. Thus, micro-Doppler feature parameter estimation is a key to accurate target recognition. In this paper, the radar echo of rotated propellers is modelled and simulated. Based on which, the distribution characteristics of the micro-motion modulation energy in time, frequency and time-frequency domain are analyzed. The micro-motion modulation energy produced by the scattering points of rotating propellers is accumulated using the Inverse-Radon (I-Radon) transform, which can be used to accomplish the estimation of micro-modulation parameter. Finally, it is proved that the proposed parameter estimation method is effective with measured data. The micro-motion parameters of aircraft can be used as the features of radar target recognition.

  4. Measurements for kinetic parameters estimation in the RA-0 research reactor

    International Nuclear Information System (INIS)

    Gomez, A; Bellino, P A

    2012-01-01

    In the present work, measurements based on the neutron noise technique and the inverse kinetic method were performed to estimate the different kinetic parameters of the reactor in its critical state. By means of the neutron noise technique, we obtained the current calibration factor of the ionization chamber M6 belonging to the power range channels of the reactor instrumentation. The maximum current allowed compatible with the maximum power authorized by the operation license was also obtained. Using the neutron noise technique, the reduced mean reproduction time (Λ*) was estimated. This parameter plays a fundamental role in the deterministic analysis of criticality accidents. Comparison with previous values justified performing new measurements to study systematic trends in the value of Λ*. Using the inverse kinetics method, the reactivity worth of the control rods was estimated, confirming the existence of spatial effects and trends previously observed (author)

  5. The estimated evacuation time for the emergency planning zone of the Kori nuclear site, with a focus on the precautionary action zone

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jang Hee; Jeong, Jae Jun [School of Mechanical Engineering, Pusan National University, Busan (Korea, Republic of); Shin, Won Ki; Song, Eun Young; Cho, Cheol Woo [Div. of Nuclear Safety, Busan Metropolitan City, Busan (Korea, Republic of)

    2016-09-15

    The emergency planning zone (EPZ) of the city of Busan is divided into the precautionary actions zone (PAZ) and the urgent protective action planning zone; which have a 5-km radius and a 20-km to 21-km radius from the nuclear power plant site, respectively. In this study, we assumed that a severe accident occurred at Shin-Kori nuclear unit 3 and evaluated the dispersion speed of radiological material at each distance at various wind speeds, and estimated the effective dose equivalent and the evacuation time of PAZ residents with the goal of supporting off-site emergency action planning for the nuclear site. The total effective dose equivalent, which shows the effect of released radioactive materials on the residents, was evaluated using the RASCAL 4.2 program. In addition, a survey of 1,036 residents was performed using a standardized questionnaire, and the resident evacuation time according to road and distance was analyzed using the VISSIM 6.0 program. According to the results obtained using the VISSIM and RASCAL programs, it would take approximately 80 to 252.2 minutes for permanent residents to move out of the PAZ boundary, 40 to 197.2 minutes for students, 60 to 232.2 minutes for the infirm, such as elderly people and those in a nursing home or hospital, and 30 to 182.2 minutes for those temporarily within the area. Consequently, in the event of any delay in the evacuation, it is estimated that the residents would be exposed to up to 10 mSv·h-1 of radiation at the Exclusion Area Boundaries (EAB) boundary and 4-6 mSv·h-1 at the PAZ boundary. It was shown that the evacuation time for the residents is adequate in light of the time lapse from the initial moment of a severe accident to the radiation release. However, in order to minimize the evacuation time, it is necessary to maintain a system of close collaboration to avoid traffic congestion and spontaneous evacuation attempts.

  6. The estimated evacuation time for the emergency planning zone of the Kori nuclear site, with a focus on the precautionary action zone

    International Nuclear Information System (INIS)

    Lee, Jang Hee; Jeong, Jae Jun; Shin, Won Ki; Song, Eun Young; Cho, Cheol Woo

    2016-01-01

    The emergency planning zone (EPZ) of the city of Busan is divided into the precautionary actions zone (PAZ) and the urgent protective action planning zone; which have a 5-km radius and a 20-km to 21-km radius from the nuclear power plant site, respectively. In this study, we assumed that a severe accident occurred at Shin-Kori nuclear unit 3 and evaluated the dispersion speed of radiological material at each distance at various wind speeds, and estimated the effective dose equivalent and the evacuation time of PAZ residents with the goal of supporting off-site emergency action planning for the nuclear site. The total effective dose equivalent, which shows the effect of released radioactive materials on the residents, was evaluated using the RASCAL 4.2 program. In addition, a survey of 1,036 residents was performed using a standardized questionnaire, and the resident evacuation time according to road and distance was analyzed using the VISSIM 6.0 program. According to the results obtained using the VISSIM and RASCAL programs, it would take approximately 80 to 252.2 minutes for permanent residents to move out of the PAZ boundary, 40 to 197.2 minutes for students, 60 to 232.2 minutes for the infirm, such as elderly people and those in a nursing home or hospital, and 30 to 182.2 minutes for those temporarily within the area. Consequently, in the event of any delay in the evacuation, it is estimated that the residents would be exposed to up to 10 mSv·h-1 of radiation at the Exclusion Area Boundaries (EAB) boundary and 4-6 mSv·h-1 at the PAZ boundary. It was shown that the evacuation time for the residents is adequate in light of the time lapse from the initial moment of a severe accident to the radiation release. However, in order to minimize the evacuation time, it is necessary to maintain a system of close collaboration to avoid traffic congestion and spontaneous evacuation attempts

  7. An International Comparison of Tax Assistance for Research and Development: Estimates and Policy Implication

    Directory of Open Access Journals (Sweden)

    John Lester

    2014-11-01

    Full Text Available Business spending on research and development (R&D is generally recognized as a private activity providing broader economic benefits that justify government support. But subsidizing R&D has costs as well as benefits, and governments need to exercise judgement to ensure that subsidies are set at a level that results in a net economic benefit for society as a whole, not just for the recipients of the assistance. A key finding of the international comparison undertaken in this paper is that Canada and nine other of the 36 countries in the comparison group are providing R&D subsidies that are likely too high to generate a net economic benefit. Subsidy rates in this group of countries range from 25 to 45 per cent. The risk of excessive subsidization is confined to small firms in Canada, which receive a subsidy of almost 41 per cent through the tax system. Canada’s subsidy rate for small firms is the third highest, behind Chile and France. Other countries providing subsidy rates close to 40 per cent are Spain and India. This paper also assesses several design features of tax assistance measures, including enhanced benefits for small and young firms, refundability of benefits and incentives based on increases in R&D spending above a base level. While the best policy for R&D subsidies may be a uniform rate for all businesses regardless of age or size, the case for favouring young firms is somewhat stronger than for favouring all small firms. Focusing on young firms avoids providing benefits to small firms that are not growth-oriented; but, it is difficult to design a program that can be completely restricted to young firms since entrepreneurs would have an incentive to create new firms to avoid losing higher benefits. Even with this “leakage”, however, an age-dependent incentive could be more cost-effective than size-dependent enhanced benefits. There is a particularly strong case for providing refundability to young firms, which are unlikely to

  8. Support vector machine based estimation of remaining useful life: current research status and future trends

    International Nuclear Information System (INIS)

    Huang, Hong Zhong; Wang, Hai Kun; Li, Yan Feng; Zhang, Longlong; Liu, Zhiliang

    2015-01-01

    Estimation of remaining useful life (RUL) is helpful to manage life cycles of machines and to reduce maintenance cost. Support vector machine (SVM) is a promising algorithm for estimation of RUL because it can easily process small training sets and multi-dimensional data. Many SVM based methods have been proposed to predict RUL of some key components. We did a literature review related to SVM based RUL estimation within a decade. The references reviewed are classified into two categories: improved SVM algorithms and their applications to RUL estimation. The latter category can be further divided into two types: one, to predict the condition state in the future and then build a relationship between state and RUL; two, to establish a direct relationship between current state and RUL. However, SVM is seldom used to track the degradation process and build an accurate relationship between the current health condition state and RUL. Based on the above review and summary, this paper points out that the ability to continually improve SVM, and obtain a novel idea for RUL prediction using SVM will be future works.

  9. Estimating motor carrier management information system crash file underreporting from carrier records : research brief.

    Science.gov (United States)

    2017-08-01

    This study estimated a significant amount of underreporting to the MCMIS crash file by the States, for the carriers who cooperated in the study. For the study carriers, it appears that the MCMIS file contained about 66 percent of their reportable cra...

  10. Exploratory graph analysis: A new approach for estimating the number of dimensions in psychological research

    NARCIS (Netherlands)

    Golino, H.F.; Epskamp, S.

    2017-01-01

    The estimation of the correct number of dimensions is a long-standing problem in psychometrics. Several methods have been proposed, such as parallel analysis (PA), Kaiser-Guttman’s eigenvalue-greater-than-one rule, multiple average partial procedure (MAP), the maximum-likelihood approaches that use

  11. The Application Research of Inverse Finite Element Method for Frame Deformation Estimation

    Directory of Open Access Journals (Sweden)

    Yong Zhao

    2017-01-01

    Full Text Available A frame deformation estimation algorithm is investigated for the purpose of real-time control and health monitoring of flexible lightweight aerospace structures. The inverse finite element method (iFEM for beam deformation estimation was recently proposed by Gherlone and his collaborators. The methodology uses a least squares principle involving section strains of Timoshenko theory for stretching, torsion, bending, and transverse shearing. The proposed methodology is based on stain-displacement relations only, without invoking force equilibrium. Thus, the displacement fields can be reconstructed without the knowledge of structural mode shapes, material properties, and applied loading. In this paper, the number of the locations where the section strains are evaluated in the iFEM is discussed firstly, and the algorithm is subsequently investigated through a simple supplied beam and an experimental aluminum wing-like frame model in the loading case of end-node force. The estimation results from the iFEM are compared with reference displacements from optical measurement and computational analysis, and the accuracy of the algorithm estimation is quantified by the root-mean-square error and percentage difference error.

  12. Nonparametric estimation for censored mixture data with application to the Cooperative Huntington’s Observational Research Trial

    Science.gov (United States)

    Wang, Yuanjia; Garcia, Tanya P.; Ma, Yanyuan

    2012-01-01

    This work presents methods for estimating genotype-specific distributions from genetic epidemiology studies where the event times are subject to right censoring, the genotypes are not directly observed, and the data arise from a mixture of scientifically meaningful subpopulations. Examples of such studies include kin-cohort studies and quantitative trait locus (QTL) studies. Current methods for analyzing censored mixture data include two types of nonparametric maximum likelihood estimators (NPMLEs) which do not make parametric assumptions on the genotype-specific density functions. Although both NPMLEs are commonly used, we show that one is inefficient and the other inconsistent. To overcome these deficiencies, we propose three classes of consistent nonparametric estimators which do not assume parametric density models and are easy to implement. They are based on the inverse probability weighting (IPW), augmented IPW (AIPW), and nonparametric imputation (IMP). The AIPW achieves the efficiency bound without additional modeling assumptions. Extensive simulation experiments demonstrate satisfactory performance of these estimators even when the data are heavily censored. We apply these estimators to the Cooperative Huntington’s Observational Research Trial (COHORT), and provide age-specific estimates of the effect of mutation in the Huntington gene on mortality using a sample of family members. The close approximation of the estimated non-carrier survival rates to that of the U.S. population indicates small ascertainment bias in the COHORT family sample. Our analyses underscore an elevated risk of death in Huntington gene mutation carriers compared to non-carriers for a wide age range, and suggest that the mutation equally affects survival rates in both genders. The estimated survival rates are useful in genetic counseling for providing guidelines on interpreting the risk of death associated with a positive genetic testing, and in facilitating future subjects at risk

  13. Estimation on the Flow Phenomena and the Pressure Loss for the Inlet Part of a Research Reactor Vessel

    International Nuclear Information System (INIS)

    Seo, Kyoung Woo; Oh, Jae Min; Seo, Jae Kwang; Yoon, Ju Hyeon; Lee, Doo Jeong

    2009-01-01

    For a research reactor, a conceptual primary cooling system (PCS) was designed for an adequate cooling to the reactor core. The developed primary cooling circuit consisted of decay tanks, pumps, heat exchangers, vacuum breakers, some isolation and check valves, connection piping, and instruments. The main function of the primary cooling pumps (PCPs) of the PCS was to circulate the reactor coolant through the fuel core and the heat exchangers during a normal operation. The head according to the design flow rate which was determined by the thermal hydraulic design analysis for the core should be estimated to design the PCPs in the fluid system. The pressure loss in the PCS can be calculated by the dimensional analysis of the pipe flow and the head loss coefficient of the components. However, it is insufficient to estimate the pressure loss for 3-dimensional flow phenomena such as the flow path in the reactor with the theoretical dimensional analysis based on experimental data. The purpose of this research is to evaluate the pressure loss of the part of a research reactor vessel. For evaluating the pressure loss, the commercially available CFD computer model, FLUENT, was employed. First, for validating the application of FLUENT to the pressure loss, a simple case was calculated and compared with the Idelchik empirical correlation. Secondly, several cases for the inlet part of a research reactor vessel were estimated by a FLUENT 3- dimensional calculation

  14. Research on Single Base-Station Distance Estimation Algorithm in Quasi-GPS Ultrasonic Location System

    International Nuclear Information System (INIS)

    Cheng, X C; Su, S J; Wang, Y K; Du, J B

    2006-01-01

    In order to identify each base-station in quasi-GPS ultrasonic location system, a unique pseudo-random code is assigned to each base-station. This article primarily studies the distance estimation problem between Autonomous Guide Vehicle (AGV) and single base-station, and then the ultrasonic spread-spectrum distance measurement Time Delay Estimation (TDE) model is established. Based on the above model, the envelope correlation fast TDE algorithm based on FFT is presented and analyzed. It shows by experiments that when the m sequence used in the received signal is as same as the reference signal, there will be a sharp correlation value in their envelope correlation function after they are processed by the above algorithm; otherwise, the will be no prominent correlation value. So, the AGV can identify each base-station easily

  15. Research on Single Base-Station Distance Estimation Algorithm in Quasi-GPS Ultrasonic Location System

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, X C; Su, S J; Wang, Y K; Du, J B [Instrument Department, College of Mechatronics Engineering and Automation, National University of Defense Technology, ChangSha, Hunan, 410073 (China)

    2006-10-15

    In order to identify each base-station in quasi-GPS ultrasonic location system, a unique pseudo-random code is assigned to each base-station. This article primarily studies the distance estimation problem between Autonomous Guide Vehicle (AGV) and single base-station, and then the ultrasonic spread-spectrum distance measurement Time Delay Estimation (TDE) model is established. Based on the above model, the envelope correlation fast TDE algorithm based on FFT is presented and analyzed. It shows by experiments that when the m sequence used in the received signal is as same as the reference signal, there will be a sharp correlation value in their envelope correlation function after they are processed by the above algorithm; otherwise, the will be no prominent correlation value. So, the AGV can identify each base-station easily.

  16. Exploratory graph analysis: A new approach for estimating the number of dimensions in psychological research.

    Science.gov (United States)

    Golino, Hudson F; Epskamp, Sacha

    2017-01-01

    The estimation of the correct number of dimensions is a long-standing problem in psychometrics. Several methods have been proposed, such as parallel analysis (PA), Kaiser-Guttman's eigenvalue-greater-than-one rule, multiple average partial procedure (MAP), the maximum-likelihood approaches that use fit indexes as BIC and EBIC and the less used and studied approach called very simple structure (VSS). In the present paper a new approach to estimate the number of dimensions will be introduced and compared via simulation to the traditional techniques pointed above. The approach proposed in the current paper is called exploratory graph analysis (EGA), since it is based on the graphical lasso with the regularization parameter specified using EBIC. The number of dimensions is verified using the walktrap, a random walk algorithm used to identify communities in networks. In total, 32,000 data sets were simulated to fit known factor structures, with the data sets varying across different criteria: number of factors (2 and 4), number of items (5 and 10), sample size (100, 500, 1000 and 5000) and correlation between factors (orthogonal, .20, .50 and .70), resulting in 64 different conditions. For each condition, 500 data sets were simulated using lavaan. The result shows that the EGA performs comparable to parallel analysis, EBIC, eBIC and to Kaiser-Guttman rule in a number of situations, especially when the number of factors was two. However, EGA was the only technique able to correctly estimate the number of dimensions in the four-factor structure when the correlation between factors were .7, showing an accuracy of 100% for a sample size of 5,000 observations. Finally, the EGA was used to estimate the number of factors in a real dataset, in order to compare its performance with the other six techniques tested in the simulation study.

  17. Il campo dello sviluppo e le migrazioni contemporanee: analisi di un’esperienza di ricerca - The development field and contemporary migrations: focusing on a research experience

    Directory of Open Access Journals (Sweden)

    Selenia Marabello

    2014-11-01

    Full Text Available The relationship between migration and development, mainly connotated in favourable terms, proposes with urgency migrants as development agents. They are defined as the new diasporas. Exploring a co-development project financed by the MIDA Ghana-Senegal Programme involving Ghanaian migrants in Modena (Italy, a retrospective analysis focuses on the research setting conditions and opportunities. As an anthropologist, the researcher was first involved as a consultant for the evaluation project implementation and subsequently continued the analysis within academic institutions. With the aim to illustrate the potentialities for applied anthropology, the author will look at the discrepancies and the circular nature of the ethnographic data production and elaboration within the two fieldwork experiences.

  18. Design-related bias in estimates of accuracy when comparing imaging tests: examples from breast imaging research

    International Nuclear Information System (INIS)

    Houssami, Nehmat; Ciatto, Stefano

    2010-01-01

    This work highlights concepts on the potential for design-related factors to bias estimates of test accuracy in comparative imaging research. We chose two design factors, selection of eligible subjects and the reference standard, to examine the effect of design limitations on estimates of accuracy. Estimates of sensitivity in a study of the comparative accuracy of mammography and ultrasound differed according to how subjects were selected. Comparison of a new imaging test with an existing test should distinguish whether the new test is to be used as a replacement for, or as an adjunct to, the conventional test, to guide the method for subject selection. Quality of the reference standard, examined in a meta-analysis of preoperative breast MRI, varied across studies and was associated with estimates of incremental accuracy. Potential solutions to deal with the reference standard are outlined where an ideal reference standard may not be available in all subjects. These examples of breast imaging research demonstrate that design-related bias, when comparing a new imaging test with a conventional imaging test, may bias accuracy in a direction that favours the new test by overestimating the accuracy of the new test or by underestimating that of the conventional test. (orig.)

  19. Human Heredity and Health (H3) in Africa Kidney Disease Research Network: A Focus on Methods in Sub-Saharan Africa.

    Science.gov (United States)

    Osafo, Charlotte; Raji, Yemi Raheem; Burke, David; Tayo, Bamidele O; Tiffin, Nicki; Moxey-Mims, Marva M; Rasooly, Rebekah S; Kimmel, Paul L; Ojo, Akinlolu; Adu, Dwomoa; Parekh, Rulan S

    2015-12-07

    CKD affects an estimated 14% of adults in sub-Saharan Africa, but very little research has been done on the cause, progression, and prevention of CKD there. As part of the Human Heredity and Health in Africa (H3Africa) Consortium, the H3Africa Kidney Disease Research Network was established to study prevalent forms of kidney disease in sub-Saharan Africa and increase the capacity for genetics and genomics research. The study is performing comprehensive phenotypic characterization and analyzing environmental and genetic factors from nine clinical centers in four African countries (Ghana, Nigeria, Ethiopia, and Kenya) over a 5-year period. Approximately 4000 participants with specified kidney disease diagnoses and 4000 control participants will be enrolled in the four African countries. In addition, approximately 50 families with hereditary glomerular disease will be enrolled. The study includes both pediatric and adult participants age research infrastructure can be successfully established in Africa. This study will provide clinical, biochemical, and genotypic data that will greatly increase the understanding of CKD in sub-Saharan Africa. Copyright © 2015 by the American Society of Nephrology.

  20. Material focus

    DEFF Research Database (Denmark)

    Sokoler, Tomas; Vallgårda, Anna K. A.

    2009-01-01

    In this paper we build on the notion of computational composites, which hold a material perspective on computational technology. We argue that a focus on the material aspects of the technology could be a fruitful approach to achieve new expressions and to gain a new view on the technology's role...... in design. We study two of the computer's material properties: computed causality and connectability and through developing two computational composites that utilize these properties we begin to explore their potential expressions....

  1. A systematic review of biochar research, with a focus on its stability in situ and its promise as a climate mitigation strategy.

    Directory of Open Access Journals (Sweden)

    Noel P Gurwick

    Full Text Available BACKGROUND: Claims about the environmental benefits of charring biomass and applying the resulting "biochar" to soil are impressive. If true, they could influence land management worldwide. Alleged benefits include increased crop yields, soil fertility, and water-holding capacity; the most widely discussed idea is that applying biochar to soil will mitigate climate change. This claim rests on the assumption that biochar persists for hundreds or thousands of years, thus storing carbon that would otherwise decompose. We conducted a systematic review to quantify research effort directed toward ten aspects of biochar and closely evaluated the literature concerning biochar's stability. FINDINGS: We identified 311 peer-reviewed research articles published through 2011. We found very few field studies that addressed biochar's influence on several ecosystem processes: one on soil nutrient loss, one on soil contaminants, six concerning non-CO2 greenhouse gas (GHG fluxes (some of which fail to support claims that biochar decreases non-CO2 GHG fluxes, and 16-19 on plants and soil properties. Of 74 studies related to biochar stability, transport or fate in soil, only seven estimated biochar decomposition rates in situ, with mean residence times ranging from 8 to almost 4,000 years. CONCLUSIONS: Our review shows there are not enough data to draw conclusions about how biochar production and application affect whole-system GHG budgets. Wide-ranging estimates of a key variable, biochar stability in situ, likely result from diverse environmental conditions, feedstocks, and study designs. There are even fewer data about the extent to which biochar stimulates decomposition of soil organic matter or affects non-CO2 GHG emissions. Identifying conditions where biochar amendments yield favorable GHG budgets requires a systematic field research program. Finally, evaluating biochar's suitability as a climate mitigation strategy requires comparing its effects with

  2. RESEARCH ON THE BREEDING VALUE ESTIMATION FOR BEEF TRAITS BY A SIMPLIFIED MIXED MODEL

    Directory of Open Access Journals (Sweden)

    Agatha POPESCU

    2014-10-01

    Full Text Available The paper purpose was to apply a simplified mixed model BLUP for estimating bulls' breeding value for meat production in terms of weight daily gain and establish their hierarchy, Also, it aimed to compare the bulls' ranging obtained by a simplified BLUP mixed model with their hierarchy set up by contemporary comparison. A sample of 1,705 half sibs steers, offspring of 106 Friesian bulls were used as biological material. Bulls' breeding value varied between + 244.5 g for the best bull and -204.7 g for the bull with the weakest records. A number of 57 bulls ( 53.77% registered positive breeding values. The accuracy of the breeding value estimation varied between 80, the highest precision, in case of the bull number 21 and 53, the lowest precision, in case of the bull number 38. A number of 7 bulls of the total of 57 with a positive breeding value were situated aproximately on the same positions at a difference of 0 to 1 points on the both lists established by BLUP and contemporary comparison. As a conclusion, BLUP could be largely and easily applied in bull evaluation for meat production traits in term of weight daily gain, considered the key parameter during the fattening period and its precision is very high, a guarantee that the bulls' hierarchy is a correct one. If a farmer would chose a high breeding value bull from a catalogue, he could be sure of the improvement of beef production by genetic gain.

  3. Topics on the problem of genetic risk estimates health research foundation

    International Nuclear Information System (INIS)

    Nakai, Sayaka

    1995-01-01

    Reanalysis of the data on untoward pregnancy outcome (UPO) for atomic bomb survivors was undertaken based on following current results of cytogenetic studies obtained in Japan: 1) Human gametes were very sensitive to the production of chromosome aberrations either spontaneous or radiation induced origin. 2) The shape of dose-response relations against to radiations showed humped curve at relatively low dose-range below 3Gy. 3) Existence of very severe selection to the embryo having chromosome aberrations represented during fetus development before the birth. It was concluded that 1) Humped dose-response model was more fitted than the linear dose model. 2) Regression coefficient for the slope of UPO at low doses derived from humped dose model was about 6 times more higher than the previous value based on linear model. 3) Risk factor for genetic detriment in term of UPO was estimated as 0.015/Gy under the condition exposed radiation below 1Gy. 4) It was difficult to find out positive evidence supporting the view which is given by Neel et al. that present estimates of doubling dose based on mouse data thought to be underestimated figure. (author)

  4. The Pitt Innovation Challenge (PInCh): Driving Innovation in Translational Research Through an Incentive-Based, Problem-Focused Competition.

    Science.gov (United States)

    Fitzpatrick, Nicole Edgar; Maier, John; Yasko, Laurel; Mathias, David; Qua, Kacy; Wagner, Erika; Miller, Elizabeth; Reis, Steven E

    2017-05-01

    Translational research aims to move scientific discoveries across the biomedical spectrum from the laboratory to humans, and to ultimately transform clinical practice and public health policies. Despite efforts to accelerate translational research through national initiatives, several major hurdles remain. The authors created the Pitt Innovation Challenge (PInCh) as an incentive-based, problem-focused approach to solving identified clinical or public health problems at the University of Pittsburgh Clinical and Translational Science Institute in spring 2014. With input from a broad range of stakeholders, PInCh leadership arrived at the challenge question: How do we empower individuals to take control of their own health outcomes? The authors developed the PInCh's three-round proposal submission and review process as well as an online contest management tool to support the process. Ninety-two teams submitted video proposals in round one. Proposals included mobile applications (29; 32%), other information technology (19; 21%), and community program (22; 24%) solutions. Ten teams advanced to the final round, where three were awarded $100,000 to implement their solution over 12 months. In a 6-month follow-up survey, 6/11 (55%) team leaders stated the PInCh helped to facilitate connections outside their normal sphere of collaborators. Additional educational training sessions related to problem-focused research will be developed. The PInCh will be expanded to engage investment and industry communities to facilitate the translation of solutions to clinical practice via commercialization pathways. External organizations and other universities will be engaged to use the PInCh as a mechanism to fuel innovation in their spaces.

  5. Estimates of Arab world research productivity associated with groundwater: a bibliometric analysis

    Science.gov (United States)

    Zyoud, Shaher H.; Fuchs-Hanusch, Daniela

    2017-06-01

    The sustainable management of groundwater resources is a pressing necessity for most countries. As most of the Arab world is facing severe water scarcity, threats of depletion of non-renewable groundwater, and problems of pollution and salt-water intrusions into groundwater aquifers, much effort should be devoted to eliminate these dangers in advance. This work was devoted to bring up insights into Arab world research activities in groundwater, which is a crucial task to identify their status and can help in shaping up and improving future research activities. A bibliometric analysis has been conducted to track these activities. The study identified 1417 documents which represent 3.3% of global research productivity. Egypt was the most productive country (313; 22.1%), followed by Saudi Arabia (254; 17.9%). Total citations were 9720 with an average of 6.9. The h-index of the retrieved documents was 39, and the highest one was 22 for Egypt. The most common subject category was Environmental Science, and the most productive journal was Arabian Journal of Geosciences (99; 7.0%). In international research collaboration, France was the most collaborated country with Arab world (125; 8.8%), followed by the United States (113; 8.0%). The most productive institution was King Abdul-Aziz University, Saudi Arabia (66; 4.7%). The outcomes shows remarkable improvements in groundwater research activities originated from the Arab world. Even though, constructive efforts should be pursued vigorously to bridge the gaps in groundwater-based research. Moreover, promotion of better evaluation tools to assess the risks arising from the mismanagement of groundwater resources is required urgently.

  6. The evaluation of scientific research on the basis of estimation parameters in economics

    Directory of Open Access Journals (Sweden)

    Salvatore Lorusso

    2014-12-01

    Full Text Available Below are some considerations following on from a past Editorial entitled “The evaluation of scientific research: the result of merit-based or discretionary criteria?” published in issue No.11 (2011 of the historical-technical journal “Conservation Science in Cultural Heritage”. The Editorial looked at various tools for evaluating scientific research and expressed some reservations about the bibliometric criteria: - Impact Factor (IF, the most well-known bibliometric tool, owned by Thomson Reuters – Institute for Scientific Information (ISI, which collects data from over 14,000 journals in its web portal: an evaluation system that determines the frequency with which an article is cited in a given period; - Peer Review, a quality indicator typically used in selecting articles for publication; - Open Linking, a reference service offered by aggregators which transforms citations into hyperlinks and allows researchers to browse online from article to article regardless of the journal or publisher; - H Factor or H Index, which aims to quantify the overall scientific contribution of a researcher.

  7. Strategies for Handling Missing Data with Maximum Likelihood Estimation in Career and Technical Education Research

    Science.gov (United States)

    Lee, In Heok

    2012-01-01

    Researchers in career and technical education often ignore more effective ways of reporting and treating missing data and instead implement traditional, but ineffective, missing data methods (Gemici, Rojewski, & Lee, 2012). The recent methodological, and even the non-methodological, literature has increasingly emphasized the importance of…

  8. Innovative research reactor core designed. Estimation and analysis of gamma heating distribution

    International Nuclear Information System (INIS)

    Setiyanto

    2014-01-01

    The Gamma heating value is an important factor needed for safety analysis of each experiments that will be realized on research reactor core. Gamma heat is internal heat source occurs in each irradiation facilities or any material irradiated in reactor core. This value should be determined correctly because of the safety related problems. The gamma heating value is in general depend on. reactor core characteristics, different one and other, and then each new reactor design should be completed by gamma heating data. The Innovative Research Reactor is one of the new reactor design that should be completed with any safety data, including the gamma heating value. For this reasons, calculation and analysis of gamma heating in the hole of reactor core and irradiation facilities in reflector had been done by using of modified and validated Gamset computer code. The result shown that gamma heating value of 11.75 W/g is the highest value at the center of reactor core, higher than gamma heating value of RSG-GAS. However, placement of all irradiation facilities in reflector show that safety characteristics for irradiation facilities of innovative research reactor more better than RSG-GAS reactor. Regarding the results obtained, and based on placement of irradiation facilities in reflector, can be concluded that innovative research reactor more safe for any irradiation used. (author)

  9. Research on the method of information system risk state estimation based on clustering particle filter

    Science.gov (United States)

    Cui, Jia; Hong, Bei; Jiang, Xuepeng; Chen, Qinghua

    2017-05-01

    With the purpose of reinforcing correlation analysis of risk assessment threat factors, a dynamic assessment method of safety risks based on particle filtering is proposed, which takes threat analysis as the core. Based on the risk assessment standards, the method selects threat indicates, applies a particle filtering algorithm to calculate influencing weight of threat indications, and confirms information system risk levels by combining with state estimation theory. In order to improve the calculating efficiency of the particle filtering algorithm, the k-means cluster algorithm is introduced to the particle filtering algorithm. By clustering all particles, the author regards centroid as the representative to operate, so as to reduce calculated amount. The empirical experience indicates that the method can embody the relation of mutual dependence and influence in risk elements reasonably. Under the circumstance of limited information, it provides the scientific basis on fabricating a risk management control strategy.

  10. Research on the method of information system risk state estimation based on clustering particle filter

    Directory of Open Access Journals (Sweden)

    Cui Jia

    2017-05-01

    Full Text Available With the purpose of reinforcing correlation analysis of risk assessment threat factors, a dynamic assessment method of safety risks based on particle filtering is proposed, which takes threat analysis as the core. Based on the risk assessment standards, the method selects threat indicates, applies a particle filtering algorithm to calculate influencing weight of threat indications, and confirms information system risk levels by combining with state estimation theory. In order to improve the calculating efficiency of the particle filtering algorithm, the k-means cluster algorithm is introduced to the particle filtering algorithm. By clustering all particles, the author regards centroid as the representative to operate, so as to reduce calculated amount. The empirical experience indicates that the method can embody the relation of mutual dependence and influence in risk elements reasonably. Under the circumstance of limited information, it provides the scientific basis on fabricating a risk management control strategy.

  11. Research on Investment Estimation when Deciding to Start a new Business.

    Directory of Open Access Journals (Sweden)

    Guga, L.

    2014-06-01

    Full Text Available An entrepreneur has to follow several steps when deciding to start a new business. Starting a business involves planning, making key financial decisions, completing a series of legal activities, hiring reliable employees and after all of this the success of the new firm is determined by a few steps, which every manager must take into account. One of these steps is adopting a company name, the calling card of the business, taking into consideration the related tips regarding its selection. Entrepreneur must estimate the initial investment and the necessary financial resources. When talking about a company its mission must be clear and easy to understand. Thus, the description of the main activity and the general environment must be present in the business plan as well.

  12. Research of Subgraph Estimation Page Rank Algorithm for Web Page Rank

    Directory of Open Access Journals (Sweden)

    LI Lan-yin

    2017-04-01

    Full Text Available The traditional PageRank algorithm can not efficiently perform large data Webpage scheduling problem. This paper proposes an accelerated algorithm named topK-Rank,which is based on PageRank on the MapReduce platform. It can find top k nodes efficiently for a given graph without sacrificing accuracy. In order to identify top k nodes,topK-Rank algorithm prunes unnecessary nodes and edges in each iteration to dynamically construct subgraphs,and iteratively estimates lower/upper bounds of PageRank scores through subgraphs. Theoretical analysis shows that this method guarantees result exactness. Experiments show that topK-Rank algorithm can find k nodes much faster than the existing approaches.

  13. Focus: Digital

    DEFF Research Database (Denmark)

    Technology has been an all-important and defining element within the arts throughout the 20th century, and it has fundamentally changed the ways in which we produce and consume music. With this Focus we investigate the latest developments in the digital domain – and their pervasiveness and rapid...... production and reception of contemporary music and sound art. With ‘Digital’ we present four composers' very different answers to how technology impact their work. To Juliana Hodkinson it has become an integral part of her sonic writing. Rudiger Meyer analyses the relationships between art and design and how...

  14. Advanced maintenance strategies for power plant operators - introducing inter-plant life cycle management. ZES research focus 'condition-based maintenance in power engineering'

    Energy Technology Data Exchange (ETDEWEB)

    Graeber, U.

    2003-07-01

    The optimisation of maintenance activities observed in recent years can be attributed above all to the use and continuing development of testing and diagnostic techniques, to the increased level of system and component automation and to more efficient work organisation. Despite the considerable success of these efforts, the potential for further cost reductions is still far from exhausted. The risks connected to reliability, availability and safety need to be analysed in greater detail in order to ensure the sustainability of the savings already achieved as well as those yet to be realised. The systematic application of condition-based maintenance and the introduction of structured life cycle management are essential prerequisites. Within the framework of its ''Condition-Based Maintenance in Power Engineering'' research focus, the Energy Research Centre (ZES) has set up a specialist network in which experts from various institutes belonging to the Faculty of Mechanical Engineering and the Faculty of Informatic, Electrical Engineering and Information Technology can develop interdisciplinary solutions for advanced maintenance strategies. The ZES offers the industry a platform for cooperating on current issues relating to the supply of energy and supports the movement towards sustainable improvements to competitiveness through research and consulting activities. It applies professional project and quality management procedures to ensure that contracts covering interdisciplinary topics and projects are handled in a coherent manner. (orig.)

  15. Learning from research on the information behaviour of healthcare professionals: a review of the literature 2004-2008 with a focus on emotion.

    Science.gov (United States)

    Fourie, Ina

    2009-09-01

    A review, focusing on emotion, was conducted of reported studies on the information behaviour of healthcare professionals (2004-2008). Findings were intended to offer guidelines on information services and information literacy training, to note gaps in research and to raise research interest. Databases were searched for literature published from January 2004 to December 2008 and indexed on eric, Library and Information Science Abstracts, medline, PsycINFO, Social Services Abstracts, Sociological Abstracts, Health Source: Nursing/Academic Edition; Library, Information Science & Technology Abstracts; Psychology and Behavioral Sciences Collection; Social Work Abstracts; SocINDEX with Full Text; SPORTDiscus; cinhal; and the ISI Web of Knowledge databases. Key journals were manually scanned and citations followed. Literature was included if reporting on issues concerning emotion. Emotion in information behaviour in healthcare contexts is scantily addressed. This review, however, offers some insight into the difficulty in identifying and expressing information needs; sense making and the need to fill knowledge gaps; uncertainty; personality and coping skills; motivation to seeking information; emotional experiences during information seeking; self-confidence and attitude; emotional factors in the selection of information channels; and seeking information for psychological or emotional reasons. Suggestions following findings, address information literacy programs, information services and research gaps.

  16. Advanced maintenance strategies for power plant operators - introducing inter-plant life cycle management. ZES research focus 'condition-based maintenance in power engineering'

    International Nuclear Information System (INIS)

    Graeber, U.

    2003-01-01

    The optimisation of maintenance activities observed in recent years can be attributed above all to the use and continuing development of testing and diagnostic techniques, to the increased level of system and component automation and to more efficient work organisation. Despite the considerable success of these efforts, the potential for further cost reductions is still far from exhausted. The risks connected to reliability, availability and safety need to be analysed in greater detail in order to ensure the sustainability of the savings already achieved as well as those yet to be realised. The systematic application of condition-based maintenance and the introduction of structured life cycle management are essential prerequisites. Within the framework of its ''Condition-Based Maintenance in Power Engineering'' research focus, the Energy Research Centre (ZES) has set up a specialist network in which experts from various institutes belonging to the Faculty of Mechanical Engineering and the Faculty of Informatic, Electrical Engineering and Information Technology can develop interdisciplinary solutions for advanced maintenance strategies. The ZES offers the industry a platform for cooperating on current issues relating to the supply of energy and supports the movement towards sustainable improvements to competitiveness through research and consulting activities. It applies professional project and quality management procedures to ensure that contracts covering interdisciplinary topics and projects are handled in a coherent manner. (orig.)

  17. Research

    African Journals Online (AJOL)

    However, a focus on competence alone is inadequate to produce graduates who are capable of adapting to the changing needs of health systems. While knowledge and technical ... shared their responses to guided questions. There were three sessions; after each session the researcher aggregated participant responses ...

  18. Lines of experimental research in developing mathematical models for estimating internal radiation

    International Nuclear Information System (INIS)

    Bad'in, V.I.; Ermilov, A.P.; Margulis, U.Ya.; Khrushch, V.T.

    The report presents material involved with the statistical approach to the problem of modeling internal radiation and the trend of experimental research dictated by that approach. The content of a radioactive isotope in an organ must be viewed as a random function for which the ratio of two independent incorporations, on the average by probability, corresponds to the ratio of the corresponding amounts of the isotope that have accumulated in the organism. This tenet determines the principle of similarity. Specifically, it follows from it that the distribution of the arbitrary amount in the organism with multiple repetition of the experiment will be subordinate to a log-normal law. Second, the vital condition for creating the quantitative statistical model of the metabolism is a large volume of experimental data. This requires perfection of the unified rapid methods of research

  19. Nuclear based technologies for estimating microbial protein supply in ruminant livestock. Proceedings of the second research co-ordination meeting of a co-ordinated research project (phase 1)

    International Nuclear Information System (INIS)

    1999-06-01

    The Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture through its Co-ordinated Research Projects (CRPs), has been assisting national agricultural research systems in Member States to develop and apply nuclear and related techniques for improving livestock productivity. The programmes have focused on animal nutrition, animal reproduction and more recently on animal nutrition/reproduction interactions with emphasis on smallholder farming systems. The measurement of microbial protein supply to ruminant livestock has been an important area of research in ruminant nutrition. An estimate of microbial protein contribution to the intestinal protein flow is important for estimating the protein requirement of ruminant animals. Understanding the process of microbial protein synthesis has been difficult however, and due to the lack of simple and accurate methods for measuring microbial protein production in vivo, the methods used are based on complex microbial markers which require surgically prepared animals. As a result of a consultants meeting held in May 1995 to advise the Joint FAO/IAEA Division on the feasibility of using nuclear and related techniques for the development and validation of techniques for measuring microbial protein supply in ruminant animals, an FAO/IAEA Co-ordinated Research Project on Development, Standardization and Validation of Nuclear Based Technologies for Measuring Microbial Protein Supply in Ruminant Livestock for Improving Productivity was initiated in 1996, with a view to validating and adapting this technology for use in developing countries. To assist scientists participating in the CRP, a laboratory manual containing experimental protocols and methodologies for standardization and validation of the urine purine derivative technique and the development of models to suit local conditions, was published as IAEA-TECDOC-945. The present publication contains the final reports from participants in Phase 1 of the project

  20. Nuclear based technologies for estimating microbial protein supply in ruminant livestock. Proceedings of the second research co-ordination meeting of a co-ordinated research project (phase 1)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-06-01

    The Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture through its Co-ordinated Research Projects (CRPs), has been assisting national agricultural research systems in Member States to develop and apply nuclear and related techniques for improving livestock productivity. The programmes have focused on animal nutrition, animal reproduction and more recently on animal nutrition/reproduction interactions with emphasis on smallholder farming systems. The measurement of microbial protein supply to ruminant livestock has been an important area of research in ruminant nutrition. An estimate of microbial protein contribution to the intestinal protein flow is important for estimating the protein requirement of ruminant animals. Understanding the process of microbial protein synthesis has been difficult however, and due to the lack of simple and accurate methods for measuring microbial protein production in vivo, the methods used are based on complex microbial markers which require surgically prepared animals. As a result of a consultants meeting held in May 1995 to advise the Joint FAO/IAEA Division on the feasibility of using nuclear and related techniques for the development and validation of techniques for measuring microbial protein supply in ruminant animals, an FAO/IAEA Co-ordinated Research Project on Development, Standardization and Validation of Nuclear Based Technologies for Measuring Microbial Protein Supply in Ruminant Livestock for Improving Productivity was initiated in 1996, with a view to validating and adapting this technology for use in developing countries. To assist scientists participating in the CRP, a laboratory manual containing experimental protocols and methodologies for standardization and validation of the urine purine derivative technique and the development of models to suit local conditions, was published as IAEA-TECDOC-945. The present publication contains the final reports from participants in Phase 1 of the project

  1. Should Research on the Nutritional Potential and Health Benefits of Fermented Cereals Focus More on the General Health Status of Populations in Developing Countries?

    Science.gov (United States)

    Laurent-Babot, Caroline; Guyot, Jean-Pierre

    2017-07-25

    Cereal foods fermented by lactic acid bacteria are staples in many countries around the world particularly in developing countries, but some aspects of the nutritional and health benefits of traditional fermented foods in developing countries have not been sufficiently investigated compared to fermented foods in high-income countries. Today, malnutrition worldwide is characterized by a double burden, excess leading to non-communicable diseases like obesity or diabetes alongside micronutrient deficiencies. In addition, populations in developing countries suffer from infectious and parasitic diseases that can jeopardize the health benefits provided by their traditional fermented foods. Using examples, we argue that research on traditional fermented cereals in developing countries should focus more on their effect on inflammation and oxidative stress under conditions including infectious or non-infectious gut inflammation.

  2. Should Research on the Nutritional Potential and Health Benefits of Fermented Cereals Focus More on the General Health Status of Populations in Developing Countries?

    Directory of Open Access Journals (Sweden)

    Caroline Laurent-Babot

    2017-07-01

    Full Text Available Cereal foods fermented by lactic acid bacteria are staples in many countries around the world particularly in developing countries, but some aspects of the nutritional and health benefits of traditional fermented foods in developing countries have not been sufficiently investigated compared to fermented foods in high-income countries. Today, malnutrition worldwide is characterized by a double burden, excess leading to non-communicable diseases like obesity or diabetes alongside micronutrient deficiencies. In addition, populations in developing countries suffer from infectious and parasitic diseases that can jeopardize the health benefits provided by their traditional fermented foods. Using examples, we argue that research on traditional fermented cereals in developing countries should focus more on their effect on inflammation and oxidative stress under conditions including infectious or non-infectious gut inflammation.

  3. 氪气工质霍尔推力器束聚焦特性研究%Research on Beam Focusing Characteristics of Krypton Hall Thruster

    Institute of Scientific and Technical Information of China (English)

    夏国俊; 宁中喜; 欧阳磊; 王亚楠; 黎润; 于达仁

    2017-01-01

    以研究氪气替代氙气作为霍尔推力器工质时,等离子体束发散程度大等束聚焦特性问题为目的,通过以霍尔推力器磁场参数、放电电压和阳极工质流量分别作为单一变量进行实验研究,考察其对推力器等离子体束聚焦影响情况.使用HET-P70霍尔推力器进行相关实验,通过改变磁场参数来研究磁场位形对氪气工质推力器性能的影响,最终发现合适磁场位形形成的磁聚焦状态,即实验一中的工况3,可以使羽流发散角达到11.5°,此时推力器放电电压在400V,阳极工质流量3mg/s.另外,通过实验二和实验三,考察阳极工质流量和放电电压对氪等离子体束聚焦的影响机理,发现两个放电参数的变化主要改变了中性气体主电离区位置,进而影响等离子体束聚焦状态.电离位置在设定工况下外移9%,会使得羽流发散半角增大约12°.所以,磁场位形和中性气体的电离位置是影响氪等离子体束聚焦的重要因素,在对氪气霍尔推力器进行设计优化时应予重点考虑.%For the purpose to study the problems of plasma beam focusing,like bad spreading state of plas-ma beam,when krypton is used to replace xenon as the propellant of the electric propulsion,regarding magnet-ic field parameters,discharge voltage and propellant flow of anode as a single variable respectively,three exper-imental researches have been carried out to investigate their effects on beam focusing of the thruster. Experiments was made by the HET-P70 hall thruster to study the effects of magnetic field configuration on krypton thruster performance by changing the parameters of magnetic field,finally finding that the appropriate field configuration can form magnetic focusing state,as case 3 of the first experiment,it can make the plume divergence angle to be 11.5°. And the discharge voltage is 400V,while the propellant flow of anode is 3mg/s at the moment. In addi-tion,the influencing mechanism of

  4. [Research on Oil Sands Spectral Characteristics and Oil Content by Remote Sensing Estimation].

    Science.gov (United States)

    You, Jin-feng; Xing, Li-xin; Pan, Jun; Shan, Xuan-long; Liang, Li-heng; Fan, Rui-xue

    2015-04-01

    Visible and near infrared spectroscopy is a proven technology to be widely used in identification and exploration of hydrocarbon energy sources with high spectral resolution for detail diagnostic absorption characteristics of hydrocarbon groups. The most prominent regions for hydrocarbon absorption bands are 1,740-1,780, 2,300-2,340 and 2,340-2,360 nm by the reflectance of oil sands samples. These spectral ranges are dominated by various C-H overlapping overtones and combination bands. Meanwhile, there is relatively weak even or no absorption characteristics in the region from 1,700 to 1,730 nm in the spectra of oil sands samples with low bitumen content. With the increase in oil content, in the spectral range of 1,700-1,730 nm the obvious hydrocarbon absorption begins to appear. The bitumen content is the critical parameter for oil sands reserves estimation. The absorption depth was used to depict the response intensity of the absorption bands controlled by first-order overtones and combinations of the various C-H stretching and bending fundamentals. According to the Pearson and partial correlation relationships of oil content and absorption depth dominated by hydrocarbon groups in 1,740-1,780, 2,300-2,340 and 2,340-2,360 nm wavelength range, the scheme of association mode was established between the intensity of spectral response and bitumen content, and then unary linear regression(ULR) and partial least squares regression (PLSR) methods were employed to model the equation between absorption depth attributed to various C-H bond and bitumen content. There were two calibration equations in which ULR method was employed to model the relationship between absorption depth near 2,350 nm region and bitumen content and PLSR method was developed to model the relationship between absorption depth of 1,758, 2,310, 2,350 nm regions and oil content. It turned out that the calibration models had good predictive ability and high robustness and they could provide the scientific

  5. NPP estimation and seasonal change research of Gansu province in northwest China

    Science.gov (United States)

    Han, Tao; Wang, Dawei; Hao, Xiaocui; Jiang, Youyan

    2018-03-01

    Based on GIS and remote sensing technology, this paper estimates the NPP of the 2015 year-round and every season of Gansu province in northwest China by using the CASA(Carnegie Ames Stanford Approach) light energy utilization model. The result shows that the total annual NPP of Gansu province gradually decline from southeast to northwest in the space, which is in accordance with the water and heat condition in Gansu province. The results show that the summer NPP in Gansu Province is the maximum in each season. The maximum value of summer NPP in Gansu Province reached 695 (gCm-2•season-1), and the maximum value was 473 in spring, and 288 in the autumn, and the NPP in the winter in Gansu province were under 60. The fluctuation range of NPP value is large, this is due to the diversity of ecosystem types in Gansu province, including desert, grassland, farmland and forest, among them, the grassland area is the largest, and the grassland type is very diverse, the grassland coverage is obviously different, especially the low coverage grassland growth is affected by precipitation and temperature and other meteorological factors obviously.

  6. Focusing horn

    CERN Multimedia

    1980-01-01

    This was the first magnetic horn developed by Simon Van der Meer to collect antiprotons in the AD complex. It was used for the AA (antiproton accumulator). Making an antiproton beam took a lot of time and effort. Firstly, protons were accelerated to an energy of 26 GeV/c (protons at 26GeV/c, antiprotons at 3.6GeV/c) in the PS and ejected onto a metal target. From the spray of emerging particles, a magnetic horn picked out 3.6 GeV antiprotons for injection into the AA through a wide-aperture focusing quadrupole magnet. For a million protons hitting the target, just one antiproton was captured, 'cooled' and accumulated. It took 3 days to make a beam of 3 x 10^11 -, three hundred thousand million - antiprotons. The development of this technology was a key step to the functioning of CERN's Super Proton Synchrotron as a proton - antiproton collider.

  7. Reactive bromine in the low troposphere of Antarctica. Estimations at two research sites

    OpenAIRE

    Prados-Roman, Cristina; Gómez-Martín, Laura; Puentedura, Olga; Navarro-Comas, Mónica; Iglesias, Javier; Mingo, José Ramón; Pérez, Manuel; Ochoa, Héctor; Barlasina, María Elena; Carbajal, Gerardo; Yela, Margarita

    2018-01-01

    For decades, reactive halogen species (RHS) have been subject of detailed scientific research due to their influence on the oxidizing capacity of the atmosphere and on the climate. From the RHS, those containing bromine are of particular interest in the polar troposphere as a result of their link to ozone depletion events (ODEs) and to the perturbation of the cycle of e.g. the toxic mercury. Given its remoteness and related limited accessibility compared to the Arctic region, the RHS in the A...

  8. Using the cost distribution report in estimating private sector payments: what adjustments should researchers make?

    Science.gov (United States)

    Nugent, Gary; Grippen, Glen; Parris, Y C; Mitchell, Mary

    2003-06-01

    To reapportion Veterans Health Administration (VA) annual expenditures into benefit categories for comparison with estimated payments by private sector providers. Total expenditures for six VA medical centers for federal fiscal year 1999 were reapportioned by benefit category using the cost distribution report (CDR). Health benefit categories were based on those of health care insurers. Cost reapportionment was based on CDR data and reviews of source accounting and payroll documents. Actual expenditures for many benefits can be accurately identified and reapportioned using CDR data, but other expenditures were not identifiable in the CDR and required inspection of source documents. Inpatient expenditures amounting to $75,110,094 US dollars and outpatient expenditures amounting to $73,594,284 US dollars were reapportioned into other benefit categories, primarily professional fees. Expenditures for some VA benefits could not be identified because of differences in accounting and clinical practice between the VA and the community. Revisions to bring the CDR more in line with private sector payment categories would improve effectiveness for internal VA analyses and external expenditure comparisons. CDR revisions would require changes in recording some clinical workload (eg, rehabilitation and extended care) and classifying residential and domiciliary programs separate from inpatient care. Benefits that were not assigned expenditures for comparison with payments represent a potential liability if the VA were to purchase health care services in the marketplace. Variation among hospitals on expenditures not clearly identified in the CDR was significant and raises questions about the effectiveness of capitated budget methodologies using either the CDR or the decision support system.

  9. Place-focused physical activity research, human agency, and social justice in public health: taking agency seriously in studies of the built environment.

    Science.gov (United States)

    Blacksher, Erika; Lovasi, Gina S

    2012-03-01

    Built environment characteristics have been linked to health outcomes and health disparities. However, the effects of an environment on behavior may depend on human perception, interpretation, motivation, and other forms of human agency. We draw on epidemiological and ethical concepts to articulate a critique of research on the built environment and physical activity. We identify problematic assumptions and enumerate both scientific and ethical reasons to incorporate subjective perspectives and public engagement strategies into built environment research and interventions. We maintain that taking agency seriously is essential to the pursuit of health equity and the broader demands of social justice in public health, an important consideration as studies of the built environment and physical activity increasingly focus on socially disadvantaged communities. Attention to how people understand their environment and navigate competing demands can improve the scientific value of ongoing efforts to promote active living and health, while also better fulfilling our ethical obligations to the individuals and communities whose health we strive to protect. Copyright © 2011 Elsevier Ltd. All rights reserved.

  10. Tropical cyclones-Pacific Asian Research Campaign for Improvement of Intensity estimations/forecasts (T-PARCII): A research plan of typhoon aircraft observations in Japan

    Science.gov (United States)

    Tsuboki, Kazuhisa

    2017-04-01

    Typhoons are the most devastating weather system occurring in the western North Pacific and the South China Sea. Violent wind and heavy rainfall associated with a typhoon cause huge disaster in East Asia including Japan. In 2013, Supertyphoon Haiyan struck the Philippines caused a very high storm surge and more than 7000 people were killed. In 2015, two typhoons approached the main islands of Japan and severe flood occurred in the northern Kanto region. Typhoons are still the largest cause of natural disaster in East Asia. Moreover, many researches have projected increase of typhoon intensity with the climate change. This suggests that a typhoon risk is increasing in East Asia. However, the historical data of typhoon include large uncertainty. In particular, intensity data of the most intense typhoon category have larger error after the US aircraft reconnaissance of typhoon was terminated in 1987.The main objective of the present study is improvements of typhoon intensity estimations and of forecasts of intensity and track. We will perform aircraft observation of typhoon and the observed data are assimilated to numerical models to improve intensity estimation. Using radars and balloons, observations of thermodynamical and cloud-microphysical processes of typhoons will be also performed to improve physical processes of numerical model. In typhoon seasons (mostly in August and September), we will perform aircraft observations of typhoons. Using dropsondes from the aircraft, temperature, humidity, pressure, and wind are measured in surroundings of the typhoon inner core region. The dropsonde data are assimilated to a cloud-resolving model which has been developed in Nagoya University and named the Cloud Resolving Storm Simulator (CReSS). Then, more accurate estimations and forecasts of the typhoon intensity will be made as well as typhoon tracks. Furthermore, we will utilize a ground-based balloon with microscope camera, X-band precipitation radar, Ka-band cloud radar

  11. Recent estimates of capital flight

    OpenAIRE

    Claessens, Stijn; Naude, David

    1993-01-01

    Researchers and policymakers have in recent years paid considerable attention to the phenomenon of capital flight. Researchers have focused on four questions: What concept should be used to measure capital flight? What figure for capital flight will emerge, using this measure? Can the occurrence and magnitude of capital flight be explained by certain (economic) variables? What policy changes can be useful to reverse capital flight? The authors focus strictly on presenting estimates of capital...

  12. Focus: Spain

    International Nuclear Information System (INIS)

    Ferguson, M.P.

    1992-01-01

    Historically, Spain's nuclear program has had its share of successes and challenges. The country currently operates nine nuclear reactors totalling over 7,100 MWe of capacity and accounting for more than a third of Spain's electricity generation. Yet four reactors at advanced stages of construction remain mothballed due to a government-imposed moratorium, and a fire at one reactor in 1989 led to its premature closure and to a revival of anti-nuclear sentiment in the country. In the new national energy plan, Spain opted to continue the moratorium and rely upon conservation measures, additional natural gas imports, and electricity imports to meet expected demand. The current nuclear facilities will continue to operate, and the government will continue to pursue advanced reactor research, and expansion of the country's domestic uranium industry. Spain's integration into the European Community also is affecting the country's energy plans, prompting consolidation within the Spanish electricity sector in order to be more competitive in Europe

  13. Preliminary Results from Powell Research Group on Integrating GRACE Satellite and Ground-based Estimates of Groundwater Storage Changes

    Science.gov (United States)

    Scanlon, B. R.; Zhang, Z.; Reitz, M.; Rodell, M.; Sanford, W. E.; Save, H.; Wiese, D. N.; Croteau, M. J.; McGuire, V. L.; Pool, D. R.; Faunt, C. C.; Zell, W.

    2017-12-01

    Groundwater storage depletion is a critical issue for many of the major aquifers in the U.S., particularly during intense droughts. GRACE (Gravity Recovery and Climate Experiment) satellite-based estimates of groundwater storage changes have attracted considerable media attention in the U.S. and globally and interest in GRACE products continues to increase. For this reason, a Powell Research Group was formed to: (1) Assess variations in groundwater storage using a variety of GRACE products and other storage components (snow, surface water, and soil moisture) for major aquifers in the U.S., (2) Quantify long-term trends in groundwater storage from ground-based monitoring and regional and national modeling, and (3) Use ground-based monitoring and modeling to interpret GRACE water storage changes within the context of extreme droughts and over-exploitation of groundwater. The group now has preliminary estimates from long-term trends and seasonal fluctuations in water storage using different GRACE solutions, including CSR, JPL and GSFC. Approaches to quantifying uncertainties in GRACE data are included. This work also shows how GRACE sees groundwater depletion in unconfined versus confined aquifers, and plans for future work will link GRACE data to regional groundwater models. The wealth of ground-based observations for the U.S. provides a unique opportunity to assess the reliability of GRACE-based estimates of groundwater storage changes.

  14. Applied Prevalence Ratio estimation with different Regression models: An example from a cross-national study on substance use research.

    Science.gov (United States)

    Espelt, Albert; Marí-Dell'Olmo, Marc; Penelo, Eva; Bosque-Prous, Marina

    2016-06-14

    To examine the differences between Prevalence Ratio (PR) and Odds Ratio (OR) in a cross-sectional study and to provide tools to calculate PR using two statistical packages widely used in substance use research (STATA and R). We used cross-sectional data from 41,263 participants of 16 European countries participating in the Survey on Health, Ageing and Retirement in Europe (SHARE). The dependent variable, hazardous drinking, was calculated using the Alcohol Use Disorders Identification Test - Consumption (AUDIT-C). The main independent variable was gender. Other variables used were: age, educational level and country of residence. PR of hazardous drinking in men with relation to women was estimated using Mantel-Haenszel method, log-binomial regression models and poisson regression models with robust variance. These estimations were compared to the OR calculated using logistic regression models. Prevalence of hazardous drinkers varied among countries. Generally, men have higher prevalence of hazardous drinking than women [PR=1.43 (1.38-1.47)]. Estimated PR was identical independently of the method and the statistical package used. However, OR overestimated PR, depending on the prevalence of hazardous drinking in the country. In cross-sectional studies, where comparisons between countries with differences in the prevalence of the disease or condition are made, it is advisable to use PR instead of OR.

  15. Sensitivity estimations for cloud droplet formation in the vicinity of the high-alpine research station Jungfraujoch (3580 m a.s.l.

    Directory of Open Access Journals (Sweden)

    E. Hammer

    2015-09-01

    Full Text Available Aerosol radiative forcing estimates suffer from large uncertainties as a result of insufficient understanding of aerosol–cloud interactions. The main source of these uncertainties is dynamical processes such as turbulence and entrainment but also key aerosol parameters such as aerosol number concentration and size distribution, and to a much lesser extent, the composition. From June to August 2011 a Cloud and Aerosol Characterization Experiment (CLACE2011 was performed at the high-alpine research station Jungfraujoch (Switzerland, 3580 m a.s.l. focusing on the activation of aerosol to form liquid-phase clouds (in the cloud base temperature range of −8 to 5 °C. With a box model the sensitivity of the effective peak supersaturation (SSpeak, an important parameter for cloud activation, to key aerosol and dynamical parameters was investigated. The updraft velocity, which defines the cooling rate of an air parcel, was found to have the greatest influence on SSpeak. Small-scale variations in the cooling rate with large amplitudes can significantly alter CCN activation. Thus, an accurate knowledge of the air parcel history is required to estimate SSpeak. The results show that the cloud base updraft velocities estimated from the horizontal wind measurements made at the Jungfraujoch can be divided by a factor of approximately 4 to get the updraft velocity required for the model to reproduce the observed SSpeak. The aerosol number concentration and hygroscopic properties were found to be less important than the aerosol size in determining SSpeak. Furthermore turbulence is found to have a maximum influence when SSpeak is between approximately 0.2 and 0.4 %. Simulating the small-scale fluctuations with several amplitudes, frequencies and phases, revealed that independently of the amplitude, the effect of the frequency on SSpeak shows a maximum at 0.46 Hz (median over all phases and at higher frequencies, the maximum SSpeak decreases again.

  16. Estimating Cloud optical thickness from SEVIRI, for air quality research, by implementing a semi-analytical cloud retrieval algorithm

    Science.gov (United States)

    Pandey, Praveen; De Ridder, Koen; van Looy, Stijn; van Lipzig, Nicole

    2010-05-01

    Clouds play an important role in Earth's climate system. As they affect radiation hence photolysis rate coefficients (ozone formation),they also affect the air quality at the surface of the earth. Thus, a satellite remote sensing technique is used to retrieve the cloud properties for air quality research. The geostationary satellite, Meteosat Second Generation (MSG) has onboard, the Spinning Enhanced Visible and Infrared Imager (SEVIRI). The channels in the wavelength 0.6 µm and 1.64 µm are used to retrieve cloud optical thickness (COT). The study domain is over Europe covering a region between 35°N-70°N and 5°W-30°E, centred over Belgium. The steps involved in pre-processing the EUMETSAT level 1.5 images are described, which includes, acquisition of digital count number, radiometric conversion using offsets and slopes, estimation of radiance and calculation of reflectance. The Sun-earth-satellite geometry also plays an important role. A semi-analytical cloud retrieval algorithm (Kokhanovsky et al., 2003) is implemented for the estimation of COT. This approach doesn't involve the conventional look-up table approach, hence it makes the retrieval independent of numerical radiative transfer solutions. The semi-analytical algorithm is implemented on a monthly dataset of SEVIRI level 1.5 images. Minimum reflectance in the visible channel, at each pixel, during the month is accounted as the surface albedo of the pixel. Thus, monthly variation of COT over the study domain is prepared. The result so obtained, is compared with the COT products of Satellite Application Facility on Climate Monitoring (CM SAF). Henceforth, an approach to assimilate the COT for air quality research is presented. Address of corresponding author: Praveen Pandey, VITO- Flemish Institute for Technological Research, Boeretang 200, B 2400, Mol, Belgium E-mail: praveen.pandey@vito.be

  17. The Individually Focused Interview

    DEFF Research Database (Denmark)

    Clausen, Aksel Skovgaard

    2012-01-01

    relatively “strong” interviewees (interview persons: IPs) with diverse backgrounds; (2) thorough planning of the interview with well-focused themes; and (3) a thorough and repeated introduction to the interview. The omission of audio transcriptions is an obvious solution to the researcher who wants a breadth...... of range of statements stemming from the use of many more interviewees than is often possible. The Individually Focused Interview (TIFI) also provides more time for involvement in the field and further analysis....

  18. Decontamination & decommissioning focus area

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-08-01

    In January 1994, the US Department of Energy Office of Environmental Management (DOE EM) formally introduced its new approach to managing DOE`s environmental research and technology development activities. The goal of the new approach is to conduct research and development in critical areas of interest to DOE, utilizing the best talent in the Department and in the national science community. To facilitate this solutions-oriented approach, the Office of Science and Technology (EM-50, formerly the Office of Technology Development) formed five Focus AReas to stimulate the required basic research, development, and demonstration efforts to seek new, innovative cleanup methods. In February 1995, EM-50 selected the DOE Morgantown Energy Technology Center (METC) to lead implementation of one of these Focus Areas: the Decontamination and Decommissioning (D & D) Focus Area.

  19. Cellular and molecular research to reduce uncertainties in estimates of health effects from low-level radiation

    Energy Technology Data Exchange (ETDEWEB)

    Elkind, M.M.; Bedford, J.; Benjamin, S.A.; Waldren, C.A. (Colorado State Univ., Fort Collins, CO (USA)); Gotchy, R.L. (Science Applications International Corp., McLean, VA (USA))

    1990-10-01

    A study was undertaken by five radiation scientists to examine the feasibility of reducing the uncertainties in the estimation of risk due to protracted low doses of ionizing radiation. In addressing the question of feasibility, a review was made by the study group: of the cellular, molecular, and mammalian radiation data that are available; of the way in which altered oncogene properties could be involved in the loss of growth control that culminates in tumorigenesis; and of the progress that had been made in the genetic characterizations of several human and animal neoplasms. On the basis of this analysis, the study group concluded that, at the present time, it is feasible to mount a program of radiation research directed at the mechanism(s) of radiation-induced cancer with special reference to risk of neoplasia due to protracted, low doses of sparsely ionizing radiation. To implement a program of research, a review was made of the methods, techniques, and instruments that would be needed. This review was followed by a survey of the laboratories and institutions where scientific personnel and facilities are known to be available. A research agenda of the principal and broad objectives of the program is also discussed. 489 refs., 21 figs., 14 tabs.

  20. Cellular and molecular research to reduce uncertainties in estimates of health effects from low-level radiation

    International Nuclear Information System (INIS)

    Elkind, M.M.; Bedford, J.; Benjamin, S.A.; Waldren, C.A.; Gotchy, R.L.

    1990-10-01

    A study was undertaken by five radiation scientists to examine the feasibility of reducing the uncertainties in the estimation of risk due to protracted low doses of ionizing radiation. In addressing the question of feasibility, a review was made by the study group: of the cellular, molecular, and mammalian radiation data that are available; of the way in which altered oncogene properties could be involved in the loss of growth control that culminates in tumorigenesis; and of the progress that had been made in the genetic characterizations of several human and animal neoplasms. On the basis of this analysis, the study group concluded that, at the present time, it is feasible to mount a program of radiation research directed at the mechanism(s) of radiation-induced cancer with special reference to risk of neoplasia due to protracted, low doses of sparsely ionizing radiation. To implement a program of research, a review was made of the methods, techniques, and instruments that would be needed. This review was followed by a survey of the laboratories and institutions where scientific personnel and facilities are known to be available. A research agenda of the principal and broad objectives of the program is also discussed. 489 refs., 21 figs., 14 tabs

  1. Focused ultrasound in ophthalmology

    Directory of Open Access Journals (Sweden)

    Silverman RH

    2016-09-01

    Full Text Available Ronald H Silverman1,2 1Department of Ophthalmology, Columbia University Medical Center, 2F.L. Lizzi Center for Biomedical Engineering, Riverside Research, New York, NY, USA Abstract: The use of focused ultrasound to obtain diagnostically significant information about the eye goes back to the 1950s. This review describes the historical and technological development of ophthalmic ultrasound and its clinical application and impact. Ultrasound, like light, can be focused, which is crucial for formation of high-resolution, diagnostically useful images. Focused, single-element, mechanically scanned transducers are most common in ophthalmology. Specially designed transducers have been used to generate focused, high-intensity ultrasound that through thermal effects has been used to treat glaucoma (via cilio-destruction, tumors, and other pathologies. Linear and annular transducer arrays offer synthetic focusing in which precise timing of the excitation of independently addressable array elements allows formation of a converging wavefront to create a focus at one or more programmable depths. Most recently, linear array-based plane-wave ultrasound, in which the array emits an unfocused wavefront and focusing is performed solely on received data, has been demonstrated for imaging ocular anatomy and blood flow. While the history of ophthalmic ultrasound extends back over half-a-century, new and powerful technologic advances continue to be made, offering the prospect of novel diagnostic capabilities. Keywords: ophthalmic ultrasound, ultrasound biomicroscopy (UBM, high-intensity focused ultrasound (HIFU, ultrafast imaging, Doppler imaging 

  2. Adjusting for overdispersion in piecewise exponential regression models to estimate excess mortality rate in population-based research.

    Science.gov (United States)

    Luque-Fernandez, Miguel Angel; Belot, Aurélien; Quaresma, Manuela; Maringe, Camille; Coleman, Michel P; Rachet, Bernard

    2016-10-01

    In population-based cancer research, piecewise exponential regression models are used to derive adjusted estimates of excess mortality due to cancer using the Poisson generalized linear modelling framework. However, the assumption that the conditional mean and variance of the rate parameter given the set of covariates x i are equal is strong and may fail to account for overdispersion given the variability of the rate parameter (the variance exceeds the mean). Using an empirical example, we aimed to describe simple methods to test and correct for overdispersion. We used a regression-based score test for overdispersion under the relative survival framework and proposed different approaches to correct for overdispersion including a quasi-likelihood, robust standard errors estimation, negative binomial regression and flexible piecewise modelling. All piecewise exponential regression models showed the presence of significant inherent overdispersion (p-value regression modelling, with either a quasi-likelihood or robust standard errors, was the best approach as it deals with both, overdispersion due to model misspecification and true or inherent overdispersion.

  3. Processing deficits in monitoring analog and digital displays: Implications for attentional theory and mental-state estimation research

    Science.gov (United States)

    Payne, David G.; Gunther, Virginia A. L.

    1988-01-01

    Subjects performed short term memory tasks, involving both spatial and verbal components, and a visual monitoring task involving either analog or digital display formats. These two tasks (memory vs. monitoring) were performed both singly and in conjunction. Contrary to expectations derived from multiple resource theories of attentional processes, there was no evidence that when the two tasks involved the same cognitive codes (i.e., either both spatial or both verbal/linguistics) there was more of a dual task performance decrement than when the two tasks employed different cognitive codes/processes. These results are discussed in terms of their implications for theories of attentional processes and also for research in mental state estimation.

  4. Utility of Recent Studies to Assess the National Research Council 2001 Estimates of Cancer Risk from Ingested Arsenic

    Science.gov (United States)

    Gibb, Herman; Haver, Cary; Gaylor, David; Ramasamy, Santhini; Lee, Janice S.; Lobdell, Danelle; Wade, Timothy; Chen, Chao; White, Paul; Sams, Reeder

    2011-01-01

    Objective The purpose of this review is to evaluate the impact of recent epidemiologic literature on the National Research Council (NRC) assessment of the lung and bladder cancer risks from ingesting low concentrations (ecologic nature of the Taiwanese studies on which the NRC estimates are based present certain limitations, the data from these studies have particular strengths in that they describe lung and bladder cancer risks resulting from lifetime exposure in a large population and remain the best data on which to conduct quantitative risk assessment. Continued follow-up of a population in northeastern Taiwan, however, offers the best opportunity to improve the cancer risk assessment for arsenic in drinking water. Future studies of arsenic < 100 μg/L in drinking water and lung and bladder cancer should consider adequacy of the sample size, the synergistic relationship of arsenic and smoking, duration of arsenic exposure, age when exposure began and ended, and histologic subtype. PMID:21030336

  5. Plutonium focus area

    International Nuclear Information System (INIS)

    1996-08-01

    To ensure research and development programs focus on the most pressing environmental restoration and waste management problems at the U.S. Department of Energy (DOE), the Assistant Secretary for the Office of Environmental Management (EM) established a working group in August 1993 to implement a new approach to research and technology development. As part of this new approach, EM developed a management structure and principles that led to the creation of specific Focus Areas. These organizations were designed to focus the scientific and technical talent throughout DOE and the national scientific community on the major environmental restoration and waste management problems facing DOE. The Focus Area approach provides the framework for intersite cooperation and leveraging of resources on common problems. After the original establishment of five major Focus Areas within the Office of Technology Development (EM-50, now called the Office of Science and Technology), the Nuclear Materials Stabilization Task Group (EM-66) followed the structure already in place in EM-50 and chartered the Plutonium Focus Area (PFA). The following information outlines the scope and mission of the EM, EM-60, and EM-66 organizations as related to the PFA organizational structure

  6. US EPA Office of Research and Development Community-Focused Exposure and Risk Screening Tool (C-FERST) Air Pollutants 2011 web mapping service

    Data.gov (United States)

    U.S. Environmental Protection Agency — This map service displays all air-related layers used in the USEPA Community/Tribal-Focused Exposure and Risk Screening Tool (C/T-FERST) mapping application...

  7. US EPA Office of Research and Development Community-Focused Exposure and Risk Screening Tool (C-FERST) Air web mapping service

    Data.gov (United States)

    U.S. Environmental Protection Agency — This map service displays all air-related layers used in the USEPA Community/Tribal-Focused Exposure and Risk Screening Tool (C/T-FERST) mapping application...

  8. A critical review of anaesthetised animal models and alternatives for military research, testing and training, with a focus on blast damage, haemorrhage and resuscitation.

    Science.gov (United States)

    Combes, Robert D

    2013-11-01

    Military research, testing, and surgical and resuscitation training, are aimed at mitigating the consequences of warfare and terrorism to armed forces and civilians. Traumatisation and tissue damage due to explosions, and acute loss of blood due to haemorrhage, remain crucial, potentially preventable, causes of battlefield casualties and mortalities. There is also the additional threat from inhalation of chemical and aerosolised biological weapons. The use of anaesthetised animal models, and their respective replacement alternatives, for military purposes -- particularly for blast injury, haemorrhaging and resuscitation training -- is critically reviewed. Scientific problems with the animal models include the use of crude, uncontrolled and non-standardised methods for traumatisation, an inability to model all key trauma mechanisms, and complex modulating effects of general anaesthesia on target organ physiology. Such effects depend on the anaesthetic and influence the cardiovascular system, respiration, breathing, cerebral haemodynamics, neuroprotection, and the integrity of the blood-brain barrier. Some anaesthetics also bind to the NMDA brain receptor with possible differential consequences in control and anaesthetised animals. There is also some evidence for gender-specific effects. Despite the fact that these issues are widely known, there is little published information on their potential, at best, to complicate data interpretation and, at worst, to invalidate animal models. There is also a paucity of detail on the anaesthesiology used in studies, and this can hinder correct data evaluation. Welfare issues relate mainly to the possibility of acute pain as a side-effect of traumatisation in recovered animals. Moreover, there is the increased potential for animals to suffer when anaesthesia is temporary, and the procedures invasive. These dilemmas can be addressed, however, as a diverse range of replacement approaches exist, including computer and mathematical

  9. Estimates of genetic parameters, genetic trends, and inbreeding in a crossbred dairy sheep research flock in the United States.

    Science.gov (United States)

    Murphy, T W; Berger, Y M; Holman, P W; Baldin, M; Burgett, R L; Thomas, D L

    2017-10-01

    For the past 2 decades, the Spooner Agriculture Research Station (ARS) of the University of Wisconsin-Madison operated the only dairy sheep research flock in North America. The objectives of the present study were to 1) obtain estimates of genetic parameters for lactation and reproductive traits in dairy ewes, 2) estimate the amount of genetic change in these traits over time, and 3) quantify the level of inbreeding in this flock over the last 20 yr. Multiple-trait repeatability models (MTRM) were used to analyze ewe traits through their first 6 parities. The first MTRM jointly analyzed milk (180-d-adjusted milk yield [180d MY]), fat (180-d-adjusted fat yield [180d FY]), and protein (180-d-adjusted protein yield [180d PY]) yields adjusted to 180 d of lactation; number of lambs born per ewe lambing (NLB); and lactation average test-day somatic cell score (LSCS). A second MTRM analyzed 180d MY, NLB, LSCS, and percentage milk fat (%F) and percentage milk protein (%P). The 3 yield traits were moderately heritable (0.26 to 0.32) and strongly genetically correlated (0.91 to 0.96). Percentage milk fat and %P were highly heritable (0.53 and 0.61, respectively) and moderately genetically correlated (0.61). Milk yield adjusted to 180 d was negatively genetically correlated with %F and %P (-0.31 and -0.34, respectively). Ewe prolificacy was not significantly ( > 0.67) genetically correlated with yield traits, %P, or LSCS but lowly negatively correlated with %F (-0.26). Lactation somatic cell score was unfavorably genetically correlated with yield traits (0.28 to 0.39) but not significantly ( > 0.09) correlated with %F, %P, and NLB. Within-trait multiple-trait models through the first 4 parities revealed that 180d MY, 180d FY, 180d PY, %F, and %P were strongly genetically correlated across parity (0.67 to 1.00). However, the genetic correlations across parity for NLB and LSCS were somewhat lower (0.51 to 0.96). Regressing predicted breeding values for 180d MY, without and with

  10. A European Research Agenda for Somatic Symptom Disorders, Bodily Distress Disorders, and Functional Disorders: Results of an Estimate-Talk-Estimate Delphi Expert Study

    Directory of Open Access Journals (Sweden)

    Christina M. van der Feltz-Cornelis

    2018-05-01

    Full Text Available Background: Somatic Symptom Disorders (SSD, Bodily Distress Disorders (BDD and functional disorders (FD are associated with high medical and societal costs and pose a substantial challenge to the population and health policy of Europe. To meet this challenge, a specific research agenda is needed as one of the cornerstones of sustainable mental health research and health policy for SSD, BDD, and FD in Europe.Aim: To identify the main challenges and research priorities concerning SSD, BDD, and FD from a European perspective.Methods: Delphi study conducted from July 2016 until October 2017 in 3 rounds with 3 workshop meetings and 3 online surveys, involving 75 experts and 21 European countries. EURONET-SOMA and the European Association of Psychosomatic Medicine (EAPM hosted the meetings.Results: Eight research priorities were identified: (1 Assessment of diagnostic profiles relevant to course and treatment outcome. (2 Development and evaluation of new, effective interventions. (3 Validation studies on questionnaires or semi-structured interviews that assess chronic medical conditions in this context. (4 Research into patients preferences for diagnosis and treatment. (5 Development of new methodologic designs to identify and explore mediators and moderators of clinical course and treatment outcomes (6. Translational research exploring how psychological and somatic symptoms develop from somatic conditions and biological and behavioral pathogenic factors. (7 Development of new, effective interventions to personalize treatment. (8 Implementation studies of treatment interventions in different settings, such as primary care, occupational care, general hospital and specialty mental health settings. The general public and policymakers will benefit from the development of new, effective, personalized interventions for SSD, BDD, and FD, that will be enhanced by translational research, as well as from the outcomes of research into patient involvement, GP

  11. Urban adolescent high-risk sexual behavior: corroboration of focus group discussions through pile-sorting. The AIDS Youth Research Team.

    Science.gov (United States)

    Stanton, B F; Aronson, R; Borgatti, S; Galbraith, J; Feigelman, S

    1993-01-01

    Risk activities for acquisition of the human immunodeficiency virus (HIV) remain prevalent among urban adolescents. While interdisciplinary approaches to examine the variables contributing to risk/protective behaviors have been promoted, strategies for such explorations require further formulation. Recently we employed focus group discussions to explore factors placing urban adolescents at risk for engaging in HIV risk behaviors. The focus group format enables substantial interaction on a topic in a limited time period, but does not always provide expression of the full range of behavioral options. In this study we investigated the use of pile-sorts for confirmation of impressions from focus group discussions among 57 urban youths aged 10-14. The pile-sorts revealed some support for most of the views expressed in the group discussions. However, the sorts revealed more variability in views than was expressed in the group discussions. Substantial gender and age-based differences in perceptions were revealed with potentially important intervention implications.

  12. Modern contraceptive use, unmet need, and demand satisfied among women of reproductive age who are married or in a union in the focus countries of the Family Planning 2020 initiative: a systematic analysis using the Family Planning Estimation Tool.

    Science.gov (United States)

    Cahill, Niamh; Sonneveldt, Emily; Stover, John; Weinberger, Michelle; Williamson, Jessica; Wei, Chuchu; Brown, Win; Alkema, Leontine

    2018-03-03

    The London Summit on Family Planning in 2012 inspired the Family Planning 2020 (FP2020) initiative and the 120×20 goal of having an additional 120 million women and adolescent girls become users of modern contraceptives in 69 of the world's poorest countries by the year 2020. Working towards achieving 120 × 20 is crucial for ultimately achieving the Sustainable Development Goals of universal access and satisfying demand for reproductive health. Thus, a performance assessment is required to determine countries' progress. An updated version of the Family Planning Estimation Tool (FPET) was used to construct estimates and projections of the modern contraceptive prevalence rate (mCPR), unmet need for, and demand satisfied with modern methods of contraception among women of reproductive age who are married or in a union in the focus countries of the FP2020 initiative. We assessed current levels of family planning indicators and changes between 2012 and 2017. A counterfactual analysis was used to assess if recent levels of mCPR exceeded pre-FP2020 expectations. In 2017, the mCPR among women of reproductive age who are married or in a union in the FP2020 focus countries was 45·7% (95% uncertainty interval [UI] 42·4-49·1), unmet need for modern methods was 21·6% (19·7-23·9), and the demand satisfied with modern methods was 67·9% (64·4-71·1). Between 2012 and 2017 the number of women of reproductive age who are married or in a union who use modern methods increased by 28·8 million (95% UI 5·8-52·5). At the regional level, Asia has seen the mCPR among women of reproductive age who are married or in a union grow from 51·0% (95% UI 48·5-53·4) to 51·8% (47·3-56·5) between 2012 and 2017, which is slow growth, particularly when compared with a change from 23·9% (22·9-25·0) to 28·5% (26·8-30·2) across Africa. At the country level, based on a counterfactual analysis, we found that 61% of the countries that have made a commitment to FP2020 exceeded pre

  13. Winter wheat yield estimation of remote sensing research based on WOFOST crop model and leaf area index assimilation

    Science.gov (United States)

    Chen, Yanling; Gong, Adu; Li, Jing; Wang, Jingmei

    2017-04-01

    Accurate crop growth monitoring and yield predictive information are significant to improve the sustainable development of agriculture and ensure the security of national food. Remote sensing observation and crop growth simulation models are two new technologies, which have highly potential applications in crop growth monitoring and yield forecasting in recent years. However, both of them have limitations in mechanism or regional application respectively. Remote sensing information can not reveal crop growth and development, inner mechanism of yield formation and the affection of environmental meteorological conditions. Crop growth simulation models have difficulties in obtaining data and parameterization from single-point to regional application. In order to make good use of the advantages of these two technologies, the coupling technique of remote sensing information and crop growth simulation models has been studied. Filtering and optimizing model parameters are key to yield estimation by remote sensing and crop model based on regional crop assimilation. Winter wheat of GaoCheng was selected as the experiment object in this paper. And then the essential data was collected, such as biochemical data and farmland environmental data and meteorological data about several critical growing periods. Meanwhile, the image of environmental mitigation small satellite HJ-CCD was obtained. In this paper, research work and major conclusions are as follows. (1) Seven vegetation indexes were selected to retrieve LAI, and then linear regression model was built up between each of these indexes and the measured LAI. The result shows that the accuracy of EVI model was the highest (R2=0.964 at anthesis stage and R2=0.920 at filling stage). Thus, EVI as the most optimal vegetation index to predict LAI in this paper. (2) EFAST method was adopted in this paper to conduct the sensitive analysis to the 26 initial parameters of the WOFOST model and then a sensitivity index was constructed

  14. Theoretical basis, application, reliability, and sample size estimates of a Meridian Energy Analysis Device for Traditional Chinese Medicine Research

    Directory of Open Access Journals (Sweden)

    Ming-Yen Tsai

    Full Text Available OBJECTIVES: The Meridian Energy Analysis Device is currently a popular tool in the scientific research of meridian electrophysiology. In this field, it is generally believed that measuring the electrical conductivity of meridians provides information about the balance of bioenergy or Qi-blood in the body. METHODS AND RESULTS: PubMed database based on some original articles from 1956 to 2014 and the authoŕs clinical experience. In this short communication, we provide clinical examples of Meridian Energy Analysis Device application, especially in the field of traditional Chinese medicine, discuss the reliability of the measurements, and put the values obtained into context by considering items of considerable variability and by estimating sample size. CONCLUSION: The Meridian Energy Analysis Device is making a valuable contribution to the diagnosis of Qi-blood dysfunction. It can be assessed from short-term and long-term meridian bioenergy recordings. It is one of the few methods that allow outpatient traditional Chinese medicine diagnosis, monitoring the progress, therapeutic effect and evaluation of patient prognosis. The holistic approaches underlying the practice of traditional Chinese medicine and new trends in modern medicine toward the use of objective instruments require in-depth knowledge of the mechanisms of meridian energy, and the Meridian Energy Analysis Device can feasibly be used for understanding and interpreting traditional Chinese medicine theory, especially in view of its expansion in Western countries.

  15. What Matters for Staying On-Track and Graduating in Chicago Public Schools: A Focus on English Language Learners. Research Report

    Science.gov (United States)

    Gwynne, Julia; Pareja, Amber Stitziel; Ehrlich, Stacy B.; Allensworth, Elaine

    2012-01-01

    One out of every seven students in the Chicago Public Schools (CPS) is designated as an English language learner (ELL), and 30 percent of students in the entire district have been designated as ELLs at some point while enrolled in CPS. Many of the policies, programs, and resources targeting the needs of ELL students focus on students in elementary…

  16. Progress, opportunities, and key fields for groundwater quality research under the impacts of human activities in China with a special focus on western China.

    Science.gov (United States)

    Li, Peiyue; Tian, Rui; Xue, Chenyang; Wu, Jianhua

    2017-05-01

    Groundwater quality research is extremely important for supporting the safety of the water supply and human health in arid and semi-arid areas of China. This review article was constructed to report the latest research progress of groundwater quality in western China where groundwater quality is undergoing fast deterioration because of fast economic development and extensive anthropogenic activities. The opportunities brought by increasing public awareness of groundwater quality protection were also highlighted and discussed. To guide and promote further development of groundwater quality research in China, especially in western China, ten key groundwater quality research fields were proposed. The review shows that the intensification of human activities and the associated impacts on groundwater quality in China, especially in western China, has made groundwater quality research increasingly important, and has caught the attention of local, national, and international agencies and scholars. China has achieved some progress in groundwater quality research in terms of national and regional laws, regulations, and financial supports. The future of groundwater quality research in China, especially in western China, is promising reflected by the opportunities highlighted. The key research fields proposed in this article may also inform groundwater quality protection and management at the national and international level.

  17. Authentic Leadership, Research Integrity, and Institutions of Higher Learning: Why Focusing on Departmental Leadership Is Critical for Preserving the Sanctity of Science

    Science.gov (United States)

    Echols, Katherine I.

    2017-01-01

    One of the most overlooked and complex problems that universities and colleges face nation-wide is how to reduce and eliminate research misconduct. Because of the confidential nature of allegations of research misconduct and the high rate of underreporting, administrators at scholarly institutions struggle with understanding the cause of such…

  18. FAIRNESS 2016 [4. workshop for young scientists with research interests focused on physics at FAIR (Facility for Antiproton and Ion Research), Garmisch-Partenkirchen (Germany), 14-19 Feb 2016

    International Nuclear Information System (INIS)

    2016-01-01

    FAIRNESS 2016 was the fourth edition in a series of workshops designed to bring together excellent international young scientists with research interests focused on physics at FAIR (Facility for Antiproton and Ion Research) and was held on February 14-19 2016 in Garmisch-Partenkirchen, Germany. The topics of the workshops cover a wide range of aspects in both theoretical developments and current experimental status, concentrated around the four scientific pillars of FAIR. FAIR is a new accelerator complex with brand new experimental facilities, that is currently being built next to the existing GSI facility close to Darmstadt, Germany. The spirit of the conference is to bring together young scientists, e.g. young non-tenured scientists, postdocs and advanced PhD students to present their work, to foster active informal discussions and build up networks. Every participant in the meeting with the exception of the organizers gives an oral presentation, and all sessions are followed by an hour long discussion period. During the talks, questions are anonymously collected in a box to stimulate discussions. The broad physics program at FAIR is reflected in the wide range of topics covered by the workshop: • Atomic and plasma physics, biophysics, material sciences and applications • Nuclear structure, astrophysics and reactions • Physics of hot and dense nuclear matter, QCD phase transitions and critical point • Hadron Spectroscopy, Hadrons in matter and Hypernuclei • Experimental programs APPA, CBM, HADES, PANDA, NUSTAR, as well as BES, NICA and the RHIC beam energy scan For these different areas one invited speaker was selected to give a longer introductory presentation. The write-ups of the talks presented at FAIRNESS 2016 are the content of this issue of Journal of Physics: Conference Series and have been refereed according to the IOP standard for peer review. This issue constitutes therefore a collection of the forefront of research that is dedicated to the

  19. Numerical discretization-based estimation methods for ordinary differential equation models via penalized spline smoothing with applications in biomedical research.

    Science.gov (United States)

    Wu, Hulin; Xue, Hongqi; Kumar, Arun

    2012-06-01

    Differential equations are extensively used for modeling dynamics of physical processes in many scientific fields such as engineering, physics, and biomedical sciences. Parameter estimation of differential equation models is a challenging problem because of high computational cost and high-dimensional parameter space. In this article, we propose a novel class of methods for estimating parameters in ordinary differential equation (ODE) models, which is motivated by HIV dynamics modeling. The new methods exploit the form of numerical discretization algorithms for an ODE solver to formulate estimating equations. First, a penalized-spline approach is employed to estimate the state variables and the estimated state variables are then plugged in a discretization formula of an ODE solver to obtain the ODE parameter estimates via a regression approach. We consider three different order of discretization methods, Euler's method, trapezoidal rule, and Runge-Kutta method. A higher-order numerical algorithm reduces numerical error in the approximation of the derivative, which produces a more accurate estimate, but its computational cost is higher. To balance the computational cost and estimation accuracy, we demonstrate, via simulation studies, that the trapezoidal discretization-based estimate is the best and is recommended for practical use. The asymptotic properties for the proposed numerical discretization-based estimators are established. Comparisons between the proposed methods and existing methods show a clear benefit of the proposed methods in regards to the trade-off between computational cost and estimation accuracy. We apply the proposed methods t an HIV study to further illustrate the usefulness of the proposed approaches. © 2012, The International Biometric Society.

  20. Work-life balance – the impact of national policies. A comparative study between Germany and Greece with a special focus on early career researchers

    OpenAIRE

    Lola, Magda; Meyer, Dagmar M.

    2007-01-01

    A number of studies have been conducted regarding the link between good work-life balance and the representation of women in senior professional positions. However, many of these studies are not entirely applicable to the case of researchers, or they miss out on a number of aspects that are rather specific to researchers. In this paper we discuss some of the issues that have a bearing on the topic of work-life balance for researchers from the perspective of two different counties, Germany...

  1. Focus on CSIR research in water resources: antimicrobial properties of copper and its effects on micro-organisms in drinking water distribution systems

    CSIR Research Space (South Africa)

    Genthe, Bettina

    2007-08-01

    Full Text Available understanding of the mechanisms involved in copper toxicity in bacteria to better understand the potential applications of copper in treating drinking water. Further research is needed to determine why the growth continues after initial inactivation and whether...

  2. Comparing Different Approaches of Bias Correction for Ability Estimation in IRT Models. Research Report. ETS RR-08-13

    Science.gov (United States)

    Lee, Yi-Hsuan; Zhang, Jinming

    2008-01-01

    The method of maximum-likelihood is typically applied to item response theory (IRT) models when the ability parameter is estimated while conditioning on the true item parameters. In practice, the item parameters are unknown and need to be estimated first from a calibration sample. Lewis (1985) and Zhang and Lu (2007) proposed the expected response…

  3. Effectiveness of Item Response Theory (IRT) Proficiency Estimation Methods under Adaptive Multistage Testing. Research Report. ETS RR-15-11

    Science.gov (United States)

    Kim, Sooyeon; Moses, Tim; Yoo, Hanwook Henry

    2015-01-01

    The purpose of this inquiry was to investigate the effectiveness of item response theory (IRT) proficiency estimators in terms of estimation bias and error under multistage testing (MST). We chose a 2-stage MST design in which 1 adaptation to the examinees' ability levels takes place. It includes 4 modules (1 at Stage 1, 3 at Stage 2) and 3 paths…

  4. Using Focus Groups in the Consumer Research Phase of a Social Marketing Program to Promote Moderate-Intensity Physical Activity and Walking Trail Use in Sumter County, South Carolina

    OpenAIRE

    Burroughs, Ericka; Peck, Lara E; Sharpe, Patricia A; Granner, Michelle L; Bryant, Carol A; Fields, Regina

    2005-01-01

    Introduction The use of social marketing approaches in public health practice is increasing. Using marketing concepts such as the "four Ps" (product, price, place, and promotion), social marketing borrows from the principles of commercial marketing but promotes beneficial health behaviors. Consumer research is used to segment the population and develop a strategy based on those marketing concepts. In a community-based participatory research study, 17 focus groups were used in consumer researc...

  5. Subsurface contaminants focus area

    International Nuclear Information System (INIS)

    1996-08-01

    The US Department of Enregy (DOE) Subsurface Contaminants Focus Area is developing technologies to address environmental problems associated with hazardous and radioactive contaminants in soil and groundwater that exist throughout the DOE complex, including radionuclides, heavy metals; and dense non-aqueous phase liquids (DNAPLs). More than 5,700 known DOE groundwater plumes have contaminated over 600 billion gallons of water and 200 million cubic meters of soil. Migration of these plumes threatens local and regional water sources, and in some cases has already adversely impacted off-site rsources. In addition, the Subsurface Contaminants Focus Area is responsible for supplying technologies for the remediation of numerous landfills at DOE facilities. These landfills are estimated to contain over 3 million cubic meters of radioactive and hazardous buried Technology developed within this specialty area will provide efective methods to contain contaminant plumes and new or alternative technologies for development of in situ technologies to minimize waste disposal costs and potential worker exposure by treating plumes in place. While addressing contaminant plumes emanating from DOE landfills, the Subsurface Contaminants Focus Area is also working to develop new or alternative technologies for the in situ stabilization, and nonintrusive characterization of these disposal sites

  6. Subsurface contaminants focus area

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-08-01

    The US Department of Enregy (DOE) Subsurface Contaminants Focus Area is developing technologies to address environmental problems associated with hazardous and radioactive contaminants in soil and groundwater that exist throughout the DOE complex, including radionuclides, heavy metals; and dense non-aqueous phase liquids (DNAPLs). More than 5,700 known DOE groundwater plumes have contaminated over 600 billion gallons of water and 200 million cubic meters of soil. Migration of these plumes threatens local and regional water sources, and in some cases has already adversely impacted off-site rsources. In addition, the Subsurface Contaminants Focus Area is responsible for supplying technologies for the remediation of numerous landfills at DOE facilities. These landfills are estimated to contain over 3 million cubic meters of radioactive and hazardous buried Technology developed within this specialty area will provide efective methods to contain contaminant plumes and new or alternative technologies for development of in situ technologies to minimize waste disposal costs and potential worker exposure by treating plumes in place. While addressing contaminant plumes emanating from DOE landfills, the Subsurface Contaminants Focus Area is also working to develop new or alternative technologies for the in situ stabilization, and nonintrusive characterization of these disposal sites.

  7. A situated practice of ethics for participatory visual and digital methods in public health research and practice: a focus on digital storytelling.

    Science.gov (United States)

    Gubrium, Aline C; Hill, Amy L; Flicker, Sarah

    2014-09-01

    This article explores ethical considerations related to participatory visual and digital methods for public health research and practice, through the lens of an approach known as "digital storytelling." We begin by briefly describing the digital storytelling process and its applications to public health research and practice. Next, we explore 6 common challenges: fuzzy boundaries, recruitment and consent to participate, power of shaping, representation and harm, confidentiality, and release of materials. We discuss their complexities and offer some considerations for ethical practice. We hope this article serves as a catalyst for expanded dialogue about the need for high standards of integrity and a situated practice of ethics wherein researchers and practitioners reflexively consider ethical decision-making as part of the ongoing work of public health.

  8. Suggestions for the New Social Entrepreneurship Initiative: Focus on Building a Body of Research-Proven Programs, Shown to Produce Major Gains in Education, Poverty Reduction, Crime Prevention, and Other Areas

    Science.gov (United States)

    Coalition for Evidence-Based Policy, 2009

    2009-01-01

    This paper outlines a possible approach to implementing the Social Entrepreneurship initiative, focused on building a body of research-proven program models/strategies, and scaling them up, so as to produce major progress in education, poverty reduction, crime prevention, and other areas. The paper summarizes the rationale for this approach, then…

  9. Inhibitions and implications associated with celebrity participation in health-related social marketing: an exploratory research focused on HIV prevention in Portugal.

    Science.gov (United States)

    Casais, Beatriz; Proença, João F

    2012-01-01

    This article discusses motivations and inhibitions among celebrities to participate in health-related social marketing. The research identifies the implications that this involvement may have upon their lives. Results from in-depth interviews with 27 Portuguese celebrities show that they expect a fee for endorsements of commercial and government social marketing, despite the positive image they may gain from endorsing public health. The results demonstrate an absence of celebrity prejudice against HIV because of its serious nature and the social stigma attached to AIDS. This research suggests there is a positive bias and presents helpful information for negotiations between institutions and celebrities.

  10. An overview of coefficient alpha and a reliability matrix for estimating adequacy of internal consistency coefficients with psychological research measures.

    Science.gov (United States)

    Ponterotto, Joseph G; Ruckdeschel, Daniel E

    2007-12-01

    The present article addresses issues in reliability assessment that are often neglected in psychological research such as acceptable levels of internal consistency for research purposes, factors affecting the magnitude of coefficient alpha (alpha), and considerations for interpreting alpha within the research context. A new reliability matrix anchored in classical test theory is introduced to help researchers judge adequacy of internal consistency coefficients with research measures. Guidelines and cautions in applying the matrix are provided.

  11. Gas-hydrate concentration estimated from P- and S-wave velocities at the Mallik 2L-38 research well, Mackenzie Delta, Canada

    Science.gov (United States)

    Carcione, José M.; Gei, Davide

    2004-05-01

    We estimate the concentration of gas hydrate at the Mallik 2L-38 research site using P- and S-wave velocities obtained from well logging and vertical seismic profiles (VSP). The theoretical velocities are obtained from a generalization of Gassmann's modulus to three phases (rock frame, gas hydrate and fluid). The dry-rock moduli are estimated from the log profiles, in sections where the rock is assumed to be fully saturated with water. We obtain hydrate concentrations up to 75%, average values of 37% and 21% from the VSP P- and S-wave velocities, respectively, and 60% and 57% from the sonic-log P- and S-wave velocities, respectively. The above averages are similar to estimations obtained from hydrate dissociation modeling and Archie methods. The estimations based on the P-wave velocities are more reliable than those based on the S-wave velocities.

  12. Detailed Geoecological Research of Terroir with the Focus on Georelief and Soil – A Case Study of Krátke Kesy Vineyards

    Directory of Open Access Journals (Sweden)

    Falťan Vladimír

    2017-09-01

    Full Text Available The aim of this research is to present the application of the detailed geoecological research for use by the identification of natural elements of terroir, based on the example of cadastral area Krátke Kesy. The characteristics of georelief (influencing the microclimate of vineyards and soil characteristics (affecting the vineyard nutrition are the most important elements of a terroir on a local scale. We present maps of 10 types of geoecological complexes in topic dimension, whose borders were allocated on the base of georelief as a leading factor of regionalization. Foot slopes, transport slopes and terraces prevail in the vineyard. Cultivated Haplic and Luvi-Haplic Chernozem of the Danube Lowland have excellent conditions for precision agriculture. The impact of soil factors on vineyards was evaluated with the use of accredited laboratory analysis. Using statistical methods, we confirmed the hypothesis that the relationship between observed relevant soil elements in the study area and sugar content of grape is direct, and between the soil elements and acids in must is indirect. The biggest dependence was seen for magnesium, zinc and copper. Research results were presented in the form of maps and tables that can find use in vineyard and landscape-ecological practice.

  13. Focus Groups Help To Focus the Marketing Strategy.

    Science.gov (United States)

    Ashar, Hanna; Lane, Maureen

    1996-01-01

    A university-based degree completion program for adults conducted focus group research to refine market positioning and promotion. Focus groups averaged five current students and recent graduates who reflected, demographically, the current student population. Results gave insight into reasons for selecting the university, aspects of the program…

  14. Cosmological Final Focus Systems

    International Nuclear Information System (INIS)

    Irwin, J

    2004-01-01

    We develop the many striking parallels between the dynamics of light streams from distant galaxies and particle beams in accelerator final focus systems. Notably the deflections of light by mass clumps are identical to the kicks arising from the long-range beam-beam interactions of two counter-rotating particle beams (known as parasitic crossings). These deflections have sextupolar as well as quadrupolar components. We estimate the strength of such distortions for a variety of circumstances and argue that the sextupolar distortions from clumping within clusters may be observable. This possibility is enhanced by the facts that (1) the sextupolar distortions of background galaxies is a factor of 5 smaller than the quadrupolar distortion, (2) the angular orientation of the sextupolar and quadrupolar distortions from a mass distribution would be correlated, appearing as a slightly curved image, (3) these effects should be spatially clumped on the sky

  15. Blending Multiple Nitrogen Dioxide Data Sources for Neighborhood Estimates of Long-Term Exposure for Health Research.

    Science.gov (United States)

    Hanigan, Ivan C; Williamson, Grant J; Knibbs, Luke D; Horsley, Joshua; Rolfe, Margaret I; Cope, Martin; Barnett, Adrian G; Cowie, Christine T; Heyworth, Jane S; Serre, Marc L; Jalaludin, Bin; Morgan, Geoffrey G

    2017-11-07

    Exposure to traffic related nitrogen dioxide (NO 2 ) air pollution is associated with adverse health outcomes. Average pollutant concentrations for fixed monitoring sites are often used to estimate exposures for health studies, however these can be imprecise due to difficulty and cost of spatial modeling at the resolution of neighborhoods (e.g., a scale of tens of meters) rather than at a coarse scale (around several kilometers). The objective of this study was to derive improved estimates of neighborhood NO 2 concentrations by blending measurements with modeled predictions in Sydney, Australia (a low pollution environment). We implemented the Bayesian maximum entropy approach to blend data with uncertainty defined using informative priors. We compiled NO 2 data from fixed-site monitors, chemical transport models, and satellite-based land use regression models to estimate neighborhood annual average NO 2 . The spatial model produced a posterior probability density function of estimated annual average concentrations that spanned an order of magnitude from 3 to 35 ppb. Validation using independent data showed improvement, with root mean squared error improvement of 6% compared with the land use regression model and 16% over the chemical transport model. These estimates will be used in studies of health effects and should minimize misclassification bias.

  16. The Elsevier Trophoblast Research Award Lecture: Importance of metzincin proteases in trophoblast biology and placental development: a focus on ADAM12.

    Science.gov (United States)

    Aghababaei, Mahroo; Beristain, Alexander G

    2015-04-01

    Placental development is a highly regulated process requiring signals from both fetal and maternal uterine compartments. Within this complex system, trophoblasts, placental cells of epithelial lineage, form the maternal-fetal interface controlling nutrient, gas and waste exchange. The commitment of progenitor villous cytotrophoblasts to differentiate into diverse trophoblast subsets is a fundamental process in placental development. Differentiation of trophoblasts into invasive stromal- and vascular-remodeling subtypes is essential for uterine arterial remodeling and placental function. Inadequate placentation, characterized by defects in trophoblast differentiation, may underlie the earliest cellular events driving pregnancy disorders such as preeclampsia and fetal growth restriction. Molecularly, invasive trophoblasts acquire characteristics defined by profound alterations in cell-cell and cell-matrix adhesion, cytoskeletal reorganization and production of proteolytic factors. To date, most studies have investigated the importance of the matrix metalloproteinases (MMPs) and their ability to efficiently remodel components of the extracellular matrix (ECM). However, it is now becoming clear that besides MMPs, other related proteases regulate trophoblast invasion via mechanisms other than ECM turnover. In this review, we will summarize the current knowledge on the regulation of trophoblast invasion by members of the metzincin family of metalloproteinases. Specifically, we will discuss the emerging roles that A Disintegrin and Metalloproteinases (ADAMs) play in placental development, with a particular focus on the ADAM subtype, ADAM12. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Current clinical research environment: focus on psychiatry Cenário atual da pesquisa clínica: foco em psiquiatria

    Directory of Open Access Journals (Sweden)

    Sonia Mansoldo Dainesi

    2007-09-01

    Full Text Available The introduction of international guidelines on Good Clinical Practices (GCP in 1996, immediately followed by the publication of Resolution CNS 196/96 in Brazil, created a great opportunity for Brazilian research centers to participate in international trials. Such studies must be strictly monitored in order to assure compliance with the regulations, as well as with the standards of patient safety. Clear agreement among the investigator, the sponsor and the institution carrying out the study must be previously defined in order to avoid any conflicts of interest during or after the study. Operational aspects, such as the time needed to gain regulatory approval of the study design, strategies for patient recruitment/retention and appropriate logistics, are also important. In 2005, the Brazilian National Clinical Research Network was established, bringing together a number of research centers in teaching hospitals. The objective was to subsidize public clinical research with state-of-the-art practices and appropriate technical/scientific training programs. The development of research protocols that prioritize public health care needs in Brazil is other fundamental goal of this network. This article addresses general aspects of clinical research, as well as some specific issues in psychiatry. Improving the health and quality of life of the global population is certainly the major objective of all of the work done in this area.A introdução de diretrizes internacionais de Boas Práticas Clínicas, em 1996, imediatamente seguida pela publicação da Resolução do Conselho Nacional de Saúde 196/96, abriu uma grande oportunidade para a participação de centros de pesquisa brasileiros em estudos internacionais. Tais estudos devem ser estritamente monitorados, a fim de assegurar a adesão às legislações, assim como garantir a segurança dos pacientes envolvidos. A fim de evitar possíveis conflitos de interesse durante e após o estudo, todos os

  18. Exploring Children’s Peer Relationships through Verbal and Non-verbal Communication: A Qualitative Action Research Focused on Waldorf Pedagogy

    Directory of Open Access Journals (Sweden)

    Aida Milena Montenegro Mantilla

    2007-12-01

    Full Text Available This study analyzes the relationships that children around seven and eight years old establish in a classroom. It shows that peer relationships have a positive dimension with features such as the development of children’s creativity to communicate and modify norms. These features were found through an analysis of children’s verbal and non-verbal communication and an interdisciplinary view of children’s learning process from Rudolf Steiner, founder of Waldorf Pedagogy, and Jean Piaget and Lev Vygotsky, specialists in children’s cognitive and social dimensions. This research is an invitation to recognize children’s capacity to construct their own rules in peer relationships.

  19. Alliance for NanoHealth (ANH) Training Program for the development of future generations of interdisciplinary scientists and collaborative research focused upon the advancement of nanomedicine

    Energy Technology Data Exchange (ETDEWEB)

    Gorenstein, David [Univ. of Texas Health Science Center, Houston, TX (United States)

    2013-12-23

    The objectives of this program are to promote the mission of the Department of Energy (DOE) Science, Technology, Engineering, Math (STEM) Program by recruiting students to science and engineering disciplines with the intent of mentoring and supporting the next generation of scientists; to foster interdisciplinary and collaborative research under the sponsorship of ANH for the discovery and design of nano-based materials and devices with novel structures, functions, and properties; and to prepare a diverse work force of scientists, engineers, and clinicians by utilizing the unique intellectual and physical resources to develop novel nanotechnology paradigms for clinical application.

  20. Meeting Report of the 33rd Annual Meeting of the Academy of Surgical Research: Summary of Presentations, Labs, and Workshops, Focusing on Experimental Surgery, Las Vegas, NV, October 4-6, 2017.

    Science.gov (United States)

    Graham, Melanie L; Ziegelhofer, Tracy; Ehrmann, Jon

    2018-04-11

    The 33rd Annual Meeting of the Academy of Surgical Research was held from October 4 to 6, 2017 in Las Vegas, Nevada. The meeting welcomed >160 participants from 27 different states and five countries representing the organization's diverse membership of technicians, veterinarians, medical doctors, and biomedical researchers. The Academy's annual meeting is focused on promoting the advancement of professional and academic standards, education, and research related to the art and science of experimental surgery. Presentations included four invited keynote speakers and 30 selected lectures and posters. A primary strength of the meeting was that lectures were complimented with practical sessions that included four wet lab and two dry lab half-day courses. Likewise, participants were brought together in workshops emphasizing research workflow from starting experimental design to readying results for publication. In this report, we present the highlights from this meeting and some selected abstracts that illustrate the diverse scientific expertise of the Academy and progress in surgical research.

  1. Propensity score estimation to address calendar time-specific channeling in comparative effectiveness research of second generation antipsychotics.

    Directory of Open Access Journals (Sweden)

    Stacie B Dusetzina

    Full Text Available Channeling occurs when a medication and its potential comparators are selectively prescribed based on differences in underlying patient characteristics. Drug safety advisories can provide new information regarding the relative safety or effectiveness of a drug product which might increase selective prescribing. In particular, when reported adverse effects vary among drugs within a therapeutic class, clinicians may channel patients toward or away from a drug based on the patient's underlying risk for an adverse outcome. If channeling is not identified and appropriately managed it might lead to confounding in observational comparative effectiveness studies.To demonstrate channeling among new users of second generation antipsychotics following a Food and Drug Administration safety advisory and to evaluate the impact of channeling on cardiovascular risk estimates over time.Florida Medicaid data from 2001-2006.Retrospective cohort of adults initiating second generation antipsychotics. We used propensity scores to match olanzapine initiators with other second generation antipsychotic initiators. To evaluate channeling away from olanzapine following an FDA safety advisory, we estimated calendar time-specific propensity scores. We compare the performance of these calendar time-specific propensity scores with conventionally-estimated propensity scores on estimates of cardiovascular risk.Increased channeling away from olanzapine was evident for some, but not all, cardiovascular risk factors and corresponded with the timing of the FDA advisory. Covariate balance was optimized within period and across all periods when using the calendar time-specific propensity score. Hazard ratio estimates for cardiovascular outcomes did not differ across models (Conventional PS: 0.97, 95%CI: 0.81-3.18 versus calendar time-specific PS: 0.93, 95%CI: 0.77-3.04.Changes in channeling over time was evident for several covariates but had limited impact on cardiovascular risk

  2. Young Black Gay/Bisexual and Other Men Who Have Sex With Men: A Review and Content Analysis of Health-Focused Research Between 1988 and 2013.

    Science.gov (United States)

    Wade, Ryan M; Harper, Gary W

    2017-09-01

    Black young gay, bisexual, and other men who have sex with men (YGBMSM) are at high risk for negative health outcomes, though this population is underrepresented in the health literature. An extensive literature review and content analysis of health-related peer-reviewed articles (1988-2013) was conducted that targeted Black YGBMSM, examining five content areas: sexual health, health care, substance use, psychosocial functioning, and sociostructural factors. A coding sheet was created to collect information on all content areas and related subtopics and computed descriptive statistics. Out of 54 articles, most were published after 2004 ( N = 49; 90.7%) and addressed some aspect of sexual health ( N = 50; 92.6%). Few articles included content on psychosocial functioning, including bullying/harassment, suicide, and racial/ethnic identity. Data on health care delivery/receipt and health insurance were underrepresented; tobacco use and substance abuse were seldom addressed. Important sociostructural factors, including sexual networks and race-based discrimination, were poorly represented. Last, there was a noteworthy deficit of qualitative studies and research exploring intersectional identity and health. This review concludes that studies on Black YGBMSM health places sex at the forefront to the neglect of other critical health domains. More research is needed on the diverse health issues of a vulnerable and underexamined population.

  3. Study of human factors, and its basic aspects focusing the IEA-R1 research reactor operators, aiming at the prevention of accidents caused by human failures

    International Nuclear Information System (INIS)

    Martins, Maria da Penha Sanches

    2008-01-01

    This work presents a study of human factors and possible human failure reasons that can cause incidents, accidents and workers exposition, associated to risks intrinsic to the profession. The objective is to contribute with the operators of IEA-R1 reactor located at IPEN CNEN/S P. Accidents in the technological field, including the nuclear, have shown that the causes are much more connected to human failure than to system and equipment failures, what has led the regulatory bodies to consider studies on human failure. The research proposed in this work is quantitative/qualitative and also descriptive. Two questionnaires were used to collect data. The first of them was elaborated from the safety culture attributes which are described by the International Atomic Energy Agency - IAEA. The second considered individual and situational factors composing categories that could affect people in the work area. A carefully selected transcription of the theoretical basis according to the study of human factors was used. The methodology demonstrated a good reliability degree. Results lead to mediate factors which need direct actions concerning the needs of the group and of the individual. This research shows that it is necessary to have a really effective unit of planning and organization, not only to the physical and psychological health issues but also to the safety in the work. (author)

  4. A two-step approach to estimating selectivity and fishing power of research gill nets used in Greenland waters

    DEFF Research Database (Denmark)

    Hovgård, Holger

    1996-01-01

    by normal distributions and could be related to mesh size in accordance with the principle of geometrical similarity. In the second step the selection parameters were estimated by a nonlinear least squares fit. The model also estimated the relative efficiency of the two capture processes and the fishing......Catches of Atlantic cod (Gadus morhua) from Greenland gill-net surveys were analyzed by a two-step approach. In the initial step the form of the selection curve was identified as binormal, which was caused by fish being gilled or caught by the maxillae. Both capture processes could be described...

  5. The Role of Physiotherapy Extended Scope Practitioners in Musculoskeletal care with Focus on Decision Making and Clinical Outcomes: A Systematic Review of Quantitative and Qualitative Research.

    Science.gov (United States)

    Thompson, Jonathan; Yoward, Samantha; Dawson, Pamela

    2017-06-01

    Physiotherapy extended scope practitioner (ESP) roles are widely utilized in the management of musculoskeletal conditions. The present article reviews the current literature, with particular emphasis on the decision-making process, patient/clinician interaction and clinical outcomes. A systematic review of musculoskeletal extended scope practice was carried out. The review focused on the outcome of interventions, and the interactions and decision-making processes between ESPs and their patients. A wide search strategy was employed, through multiple databases, grey literature and experts in the field. Qualitative and quantitative studies alike were included and a mixed-methods synthesis approach was undertaken in analysing the findings of included studies. A total of 476 articles were identified for inclusion, 25 of which (22 quantitative and three qualitative) meeting the criteria for full quality appraisal and synthesis. It was not possible to conduct a meta-analysis owing to data heterogeneity. The results showed high patient satisfaction with the ESP role, support for ESP staff listing patients for orthopaedic surgery, a high positive correlation of decision making between ESPs and orthopaedic surgeons and evidence of a positive impact on patient outcomes. Qualitative themes reflected the importance of ESP clinical decision making and interpersonal skills and their role in patient education. There is broad support for the physiotherapy ESP role and evidence of favourable outcomes from ESP intervention. Clinical decisions made by ESPs correlate well with those of medical colleagues, although there is a lack of detail explaining the ESP decision-making process itself and the influences and mechanisms by which this occurs. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  6. Estimation on the Pressure Loss of the Conceptual Primary Cooling System and Design of the Primary Cooling Pump for a Research Reactor

    International Nuclear Information System (INIS)

    Seo, Kyoung Woo; Oh, Jae Min; Park, Jong Hark; Chae, Hee Taek; Seo, Jae Kwang; Park, Cheon Tae; Yoon, Ju Hyeon; Lee, Doo Jeong

    2009-01-01

    A new conceptual primary cooling system (PCS) for a research reactor has been designed for an adequate cooling to the reactor core which has various powers ranging from 30MW through 80MW. The developed primary cooling system consisted of decay tanks, pumps, heat exchangers, vacuum breakers, some isolation and check valves, connection piping, and instruments. Because the system flow rate should be determined by the thermal hydraulic design analysis for the core, the heads to design the primary cooling pumps (PCPs) in a PCS will be estimated by the variable system flow rates. The heads of the part of a research reactor vessel was evaluated by the previous study. The various pressure losses of the PCS can be calculated by the dimensional analysis of the pipe flow and the head loss coefficient of the components. The purpose of this research is to estimate the various pressure losses and to design the PCPs

  7. CTE's Focus on Continuous Improvement

    Science.gov (United States)

    Foster, John; Kelley, Patricia; Pritz, Sandy; Hodes, Carol

    2011-01-01

    Just one of the ways career and technical education (CTE) is revamping its image is through increased attention to data-driven instructional techniques as a means of improving and focusing instruction on what matters most. Accountability and data have increasingly become a core focus of research, news, and commentary about education in recent…

  8. Recent advances in mid- and near-infrared spectroscopy with applications for research and teaching, focusing on petrochemistry and biotechnology relevant products

    International Nuclear Information System (INIS)

    Heise, H M; Fritzsche, J; Tkatsch, H; Waag, F; Karch, K; Henze, K; Delbeck, S; Budde, J

    2013-01-01

    Mid- and near-infrared spectroscopy is introduced as a versatile analytical method for characterizing liquid and solid chemicals as obtained from petrochemistry and biotechnology processes. Besides normal transmission measurements, special equipment with silver halide fiber-optic probes allowing efficient analysis based on mid-infrared attenuated total reflection, and an accessory for near-infrared diffuse reflection measurements, are presented. The latter technique can be used advantageously for powdered samples such as microalgae biomass and polysaccharides, as well as for different tissues such as meat samples. The advantages and disadvantages of both methods, which can be used for industrial process monitoring and chemical quality control applications, are discussed, and have been used in several research projects of BSc students within their degree course of bio- and nano-technologies of our University of Applied Sciences. (paper)

  9. Recent advances in mid- and near-infrared spectroscopy with applications for research and teaching, focusing on petrochemistry and biotechnology relevant products

    Science.gov (United States)

    Heise, H. M.; Fritzsche, J.; Tkatsch, H.; Waag, F.; Karch, K.; Henze, K.; Delbeck, S.; Budde, J.

    2013-11-01

    Mid- and near-infrared spectroscopy is introduced as a versatile analytical method for characterizing liquid and solid chemicals as obtained from petrochemistry and biotechnology processes. Besides normal transmission measurements, special equipment with silver halide fiber-optic probes allowing efficient analysis based on mid-infrared attenuated total reflection, and an accessory for near-infrared diffuse reflection measurements, are presented. The latter technique can be used advantageously for powdered samples such as microalgae biomass and polysaccharides, as well as for different tissues such as meat samples. The advantages and disadvantages of both methods, which can be used for industrial process monitoring and chemical quality control applications, are discussed, and have been used in several research projects of BSc students within their degree course of bio- and nano-technologies of our University of Applied Sciences.

  10. Risk factors and study designs used in research of youths' suicide behaviour-an epidemiological discussion with focus on level of evidence

    DEFF Research Database (Denmark)

    Christiansen, Erik; Larsen, Kim Juul; Agerbo, Esben

    2014-01-01

    to level of evidence (LoE). Methods: We searched PubMed and psycINFO in order to identify relevant individual studies. Results: We included 36 studies of children and youth on suicidal behaviour and ideation-many rank low on LoE. For suicide, cohort design was often used, and mental illness (depression......Introduction: Many different epidemiology study designs have been used to analyse risk factors for suicide behaviour. The purpose of this study was to obtain an insight into the current study design used in research on youths' risk factors for suicide behaviour and to rank the studies according......, substance abuse and severity of mental illness) was the most common risk factor. Cohort studies are ranked 2b, which is high according to LoE. For suicide attempts, survey was often used, and psychopathology, substance abuse and being exposed to suicidal behaviour were the most common risk factors...

  11. Can National Research Assessment Exercises Be Used Locally to Inform Research Strategy Development? The Description of a Methodological Approach to the UK RAE 2008 Results with a Focus on One Institution

    Science.gov (United States)

    Reidpath, Daniel D.; Allotey, Pascale

    2010-01-01

    National mechanisms for comparing the research profiles of higher education institutions (HEIs) have become increasingly common. Probably the best known of these is the Research Assessment Exercise (RAE) conducted in the United Kingdom, and used as the basis for the allocation of research funding. Such exercises are expensive. They would have…

  12. A Concurrent Mixed Methods Approach to Examining the Quantitative and Qualitative Meaningfulness of Absolute Magnitude Estimation Scales in Survey Research

    Science.gov (United States)

    Koskey, Kristin L. K.; Stewart, Victoria C.

    2014-01-01

    This small "n" observational study used a concurrent mixed methods approach to address a void in the literature with regard to the qualitative meaningfulness of the data yielded by absolute magnitude estimation scaling (MES) used to rate subjective stimuli. We investigated whether respondents' scales progressed from less to more and…

  13. Prevalence Estimation and Validation of New Instruments in Psychiatric Research: An Application of Latent Class Analysis and Sensitivity Analysis

    Science.gov (United States)

    Pence, Brian Wells; Miller, William C.; Gaynes, Bradley N.

    2009-01-01

    Prevalence and validation studies rely on imperfect reference standard (RS) diagnostic instruments that can bias prevalence and test characteristic estimates. The authors illustrate 2 methods to account for RS misclassification. Latent class analysis (LCA) combines information from multiple imperfect measures of an unmeasurable latent condition to…

  14. First Order Estimates of Energy Requirements for Pollution Control. Interagency Energy-Environment Research and Development Program Report.

    Science.gov (United States)

    Barker, James L.; And Others

    This U.S. Environmental Protection Agency report presents estimates of the energy demand attributable to environmental control of pollution from stationary point sources. This class of pollution source includes powerplants, factories, refineries, municipal waste water treatment plants, etc., but excludes mobile sources such as trucks, and…

  15. Particle Accelerator Focus Automation

    Science.gov (United States)

    Lopes, José; Rocha, Jorge; Redondo, Luís; Cruz, João

    2017-08-01

    The Laboratório de Aceleradores e Tecnologias de Radiação (LATR) at the Campus Tecnológico e Nuclear, of Instituto Superior Técnico (IST) has a horizontal electrostatic particle accelerator based on the Van de Graaff machine which is used for research in the area of material characterization. This machine produces alfa (He+) and proton (H+) beams of some μA currents up to 2 MeV/q energies. Beam focusing is obtained using a cylindrical lens of the Einzel type, assembled near the high voltage terminal. This paper describes the developed system that automatically focuses the ion beam, using a personal computer running the LabVIEW software, a multifunction input/output board and signal conditioning circuits. The focusing procedure consists of a scanning method to find the lens bias voltage which maximizes the beam current measured on a beam stopper target, which is used as feedback for the scanning cycle. This system, as part of a wider start up and shut down automation system built for this particle accelerator, brings great advantages to the operation of the accelerator by turning it faster and easier to operate, requiring less human presence, and adding the possibility of total remote control in safe conditions.

  16. Particle Accelerator Focus Automation

    Directory of Open Access Journals (Sweden)

    Lopes José

    2017-08-01

    Full Text Available The Laboratório de Aceleradores e Tecnologias de Radiação (LATR at the Campus Tecnológico e Nuclear, of Instituto Superior Técnico (IST has a horizontal electrostatic particle accelerator based on the Van de Graaff machine which is used for research in the area of material characterization. This machine produces alfa (He+ and proton (H+ beams of some μA currents up to 2 MeV/q energies. Beam focusing is obtained using a cylindrical lens of the Einzel type, assembled near the high voltage terminal. This paper describes the developed system that automatically focuses the ion beam, using a personal computer running the LabVIEW software, a multifunction input/output board and signal conditioning circuits. The focusing procedure consists of a scanning method to find the lens bias voltage which maximizes the beam current measured on a beam stopper target, which is used as feedback for the scanning cycle. This system, as part of a wider start up and shut down automation system built for this particle accelerator, brings great advantages to the operation of the accelerator by turning it faster and easier to operate, requiring less human presence, and adding the possibility of total remote control in safe conditions.

  17. Use of Multiple Imputation Method to Improve Estimation of Missing Baseline Serum Creatinine in Acute Kidney Injury Research

    Science.gov (United States)

    Peterson, Josh F.; Eden, Svetlana K.; Moons, Karel G.; Ikizler, T. Alp; Matheny, Michael E.

    2013-01-01

    Summary Background and objectives Baseline creatinine (BCr) is frequently missing in AKI studies. Common surrogate estimates can misclassify AKI and adversely affect the study of related outcomes. This study examined whether multiple imputation improved accuracy of estimating missing BCr beyond current recommendations to apply assumed estimated GFR (eGFR) of 75 ml/min per 1.73 m2 (eGFR 75). Design, setting, participants, & measurements From 41,114 unique adult admissions (13,003 with and 28,111 without BCr data) at Vanderbilt University Hospital between 2006 and 2008, a propensity score model was developed to predict likelihood of missing BCr. Propensity scoring identified 6502 patients with highest likelihood of missing BCr among 13,003 patients with known BCr to simulate a “missing” data scenario while preserving actual reference BCr. Within this cohort (n=6502), the ability of various multiple-imputation approaches to estimate BCr and classify AKI were compared with that of eGFR 75. Results All multiple-imputation methods except the basic one more closely approximated actual BCr than did eGFR 75. Total AKI misclassification was lower with multiple imputation (full multiple imputation + serum creatinine) (9.0%) than with eGFR 75 (12.3%; Pcreatinine) (15.3%) versus eGFR 75 (40.5%; P<0.001). Multiple imputation improved specificity and positive predictive value for detecting AKI at the expense of modestly decreasing sensitivity relative to eGFR 75. Conclusions Multiple imputation can improve accuracy in estimating missing BCr and reduce misclassification of AKI beyond currently proposed methods. PMID:23037980

  18. Focus on Organic Conductors

    Directory of Open Access Journals (Sweden)

    Shinya Uji, Takehiko Mori and Toshihiro Takahashi

    2009-01-01

    Full Text Available Organic materials are usually thought of as electrical insulators. Progress in chemical synthesis, however, has brought us a rich variety of conducting organic materials, which can be classified into conducting polymers and molecular crystals. Researchers can realize highly conducting molecular crystals in charge-transfer complexes, where suitable combinations of organic electron donor or acceptor molecules with counter ions or other organic molecules provide charge carriers. By means of a kind of chemical doping, the charge-transfer complexes exhibit high electrical conductivity and, thanks to their highly crystalline nature, even superconductivity has been observed. This focus issue of Science and Technology of Advanced Materials is devoted to the research into such 'organic conductors'The first organic metal was (TTF(TCNQ, which was found in 1973 to have high conductivity at room temperature and a metal–insulator transition at low temperatures. The first organic superconductor was (TMTSF2PF6, whose superconductivity under high pressures was reported by J´erome in 1980. After these findings, the research on organic conductors exploded. Hundreds of organic conductors have been reported, among which more than one hundred exhibit superconductivity. Recently, a single-component organic conductor has been found with metallic conductivity down to low temperatures.In these organic conductors, in spite of their simple electronic structures, much new physics has arisen from the low dimensionality. Examples are charge and spin density waves, characteristic metal–insulator transitions, charge order, unconventional superconductivity, superconductor–insulator transitions, and zero-gap conductors with Dirac cones. The discovery of this new physics is undoubtedly derived from the development of many intriguing novel organic conductors. High quality single crystals are indispensable to the precise measurement of electronic states.This focus issue

  19. Cooperative research with the Institute of Resources and Environment Technology. Estimation and investigation of estimation method on property change accompanied with excavation. Intermediate report in 1994 and 1995 fiscal year

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    The Power Reactor and Nuclear Fuel Development Corporation (PRNFDC) and the Institute of Resources and Environment Technology (IRET) of Agency of Industrial Science and Technology conducted a cooperative research on a testing study based on in-door fundamental examination on Acoustic emission (AE) original position measuring tester to catch property change due to micro elastic wave formed with generation and propagation of rock deformation and fracture and AE measurement and specific resistance tomography under 3 years plan from 1989 fiscal year. In 1994 fiscal year, survey on the specific resistance tomography for pre-research on tunnel excavation effect test and experiment on the specific resistance measurement at in-door scale for fundamental study of estimation method were conducted. And, in 1995 fiscal year, by laying a main point of the experiment at in-door scale, the estimation and investigation on the excavation effect estimation method on a base of the past study results on the fundamental experiment results were conducted. In this paper, these experiment results conducted at IRET and PRNFDC in 1994 and 1995 fiscal years were reported. (G.K.)

  20. The Formation of Methodical Approach to Estimation of Scientific-Research, Scientific-Technical, and Innovative Activity of Institutions of Higher Education

    Directory of Open Access Journals (Sweden)

    Yermachenko Volodymyr Ye.

    2017-12-01

    Full Text Available The research is aimed at developing a methodical approach to the construction of an innovative system of estimation of research, scientific, technical, and innovative activities of higher education institutions (HEI on the basis of elaborate structured system of indicators. The proposed methodical approach contains five stages, the research discloses the content of each of them. Based on the results of a comparative analysis of international and national systems of HEI-rating, as well as the usage of economic and mathematical instrumentarium, a list of indicators for estimating their scientific activities in terms of the selected factors and directions of estimation was formed and substantiated. An approach to formation of cluster aggregates of HEI by the criterion of their scientific performance has been suggested. Proposals on formation of a HEI-rating within the limits of the allocated homogeneous groups by means of the system of integral indicators were developed. Prospects for further scientific researches in this direction imply formation of directions of development of managerial decisions in accordance with the obtained results of rating, which will be directed on strengthening and search for new ways of development of scientific activity of HEI, increase of its level of competitiveness and image, and also strengthening of its contribution to the solution of actual problems of economy and society.

  1. Research on the Effectiveness of Different Estimation Algorithm on the Autonomous Orbit Determination of Lagrangian Navigation Constellation

    Directory of Open Access Journals (Sweden)

    Youtao Gao

    2016-01-01

    Full Text Available The accuracy of autonomous orbit determination of Lagrangian navigation constellation will affect the navigation accuracy for the deep space probes. Because of the special dynamical characteristics of Lagrangian navigation satellite, the error caused by different estimation algorithm will cause totally different autonomous orbit determination accuracy. We apply the extended Kalman filter and the fading–memory filter to determinate the orbits of Lagrangian navigation satellites. The autonomous orbit determination errors are compared. The accuracy of autonomous orbit determination using fading-memory filter can improve 50% compared to the autonomous orbit determination accuracy using extended Kalman filter. We proposed an integrated Kalman fading filter to smooth the process of autonomous orbit determination and improve the accuracy of autonomous orbit determination. The square root extended Kalman filter is introduced to deal with the case of inaccurate initial error variance matrix. The simulations proved that the estimation method can affect the accuracy of autonomous orbit determination greatly.

  2. Research and Development of Methods for Estimating Physicochemical Properties of Organic Compounds of Environmental Concern. Part 2.

    Science.gov (United States)

    1981-06-01

    lar orbital considerations. The basis of light scattering in Raman spec- troscopy is the dipole moment induced in the molecule when hit by the...of 6 25-9 APPENDICES SIMPLE LINEAR REGRESSION B-1 Scatter Plot of Twenty-five Observations of Two Variables B-2 B-2 Violation of Regression Assumptions...parachor values com- puted by the Sugden method and the McGowan method, respectively. Example 12-2 Estimate the normal boiling point for nicotine . (1

  3. Variables influencing wearable sensor outcome estimates in individuals with stroke and incomplete spinal cord injury: a pilot investigation validating two research grade sensors.

    Science.gov (United States)

    Jayaraman, Chandrasekaran; Mummidisetty, Chaithanya Krishna; Mannix-Slobig, Alannah; McGee Koch, Lori; Jayaraman, Arun

    2018-03-13

    Monitoring physical activity and leveraging wearable sensor technologies to facilitate active living in individuals with neurological impairment has been shown to yield benefits in terms of health and quality of living. In this context, accurate measurement of physical activity estimates from these sensors are vital. However, wearable sensor manufacturers generally only provide standard proprietary algorithms based off of healthy individuals to estimate physical activity metrics which may lead to inaccurate estimates in population with neurological impairment like stroke and incomplete spinal cord injury (iSCI). The main objective of this cross-sectional investigation was to evaluate the validity of physical activity estimates provided by standard proprietary algorithms for individuals with stroke and iSCI. Two research grade wearable sensors used in clinical settings were chosen and the outcome metrics estimated using standard proprietary algorithms were validated against designated golden standard measures (Cosmed K4B2 for energy expenditure and metabolic equivalent and manual tallying for step counts). The influence of sensor location, sensor type and activity characteristics were also studied. 28 participants (Healthy (n = 10); incomplete SCI (n = 8); stroke (n = 10)) performed a spectrum of activities in a laboratory setting using two wearable sensors (ActiGraph and Metria-IH1) at different body locations. Manufacturer provided standard proprietary algorithms estimated the step count, energy expenditure (EE) and metabolic equivalent (MET). These estimates were compared with the estimates from gold standard measures. For verifying validity, a series of Kruskal Wallis ANOVA tests (Games-Howell multiple comparison for post-hoc analyses) were conducted to compare the mean rank and absolute agreement of outcome metrics estimated by each of the devices in comparison with the designated gold standard measurements. The sensor type, sensor location

  4. Patterns of symptom control and palliative care-focused original research articles in the International Journal of Radiation Oncology *Biology* Physics and the Radiotherapy and Oncology Journal, 2005-2014.

    Science.gov (United States)

    Shi, Diana D; DiGiovanni, Julia; Skamene, Sonia; Noveroske Philbrick, Sarah; Wang, Yanbing; Barnes, Elizabeth A; Chow, Edward; Sullivan, Adam; Balboni, Tracy A

    2018-04-01

    A significant portion of radiation treatment (30-40%) is delivered with palliative intent. Given the frequency of palliative care (PC) in radiation oncology, we determined the patterns of research focusing on symptom control and palliative care (SCPC) in two prominent radiation oncology journals from 2005-2014. Original research manuscripts published from 2005-2014 in the International Journal of Radiation Oncology *Biology* Physics (Red Journal) and the Radiotherapy and Oncology Journal (Green Journal) were reviewed to categorize articles as PC and/or SCPC. Articles were categorized as PC if it pertained to any aspect of treatment of metastatic cancer, and as SCPC if symptom control in the metastatic cancer setting was the goal of the research inquiry and/or any domain of palliative clinical practice guidelines was the goal of research inquiry. From 2005-2014, 4.9% (312/6,386) of original research articles published in the Red Journal and 3.5% (84/2,406) published in the Green Journal pertained to metastatic cancer, and were categorized as PC. In the Red Journal, 1.3% (84/6,386) of original research articles were categorized as SCPC; 1.3% (32/2,406) of articles in the Green Journal were categorized as SCPC. There was no trend observed in the proportion of SCPC articles published over time in the Red Journal (P=0.76), the Green Journal (P=0.48), or both journals in aggregate (P=0.38). Despite the fact that palliative radiotherapy is a critical part of radiation oncology practice, PC and SCPC-focused original research is poorly represented in the Red Journal and the Green Journal.

  5. Research protocol for an epidemiological study on estimating disease burden of pediatric HIV in Belgaum district, India

    Directory of Open Access Journals (Sweden)

    Anju Sinha

    2016-05-01

    Full Text Available Abstract Background Pediatric HIV is poised to become a major public health problem in India with the rising trend of HIV infection in pregnant women (Department of AIDS Control, Ministry of Health and Family Welfare, http://www.naco.gov.in. There is lack of information on the epidemiology of pediatric HIV infection in India. Existing surveillance systems tend to underestimate the Pediatric burden. The overall aim of the present study is to estimate the disease burden of pediatric HIV among children in Belgaum district in the state of Karnataka in Southern India. An innovative multipronged epidemiological approach to comb the district is proposed. Methods The primary objectives of the study would be attained under three strategies. A prospective cohort design for objective (i to determine the incidence rate of HIV by early case detection in infants and toddlers (0–18 months born to HIV infected pregnant women; and cross sectional design for objectives (ii to determine the prevalence of HIV infection in children (0–14 years of HIV infected parents and (iii to determine the prevalence of HIV in sick children (0–14 years presenting with suspected signs and symptoms using age specific criteria for screening. Burden of pediatric HIV will be calculated as a product of cases detected in each strategy multiplied by a net inflation factor for each strategy. Study participants (i (ii (iii: HIV infected pregnant women and their live born children (ii Any HIV-infected man/woman, of age 18–49 years, having a biological child of age 0–14 years (iii Sick children of age 0–14 years presenting with suspected signs and symptoms and satisfying age-specific criteria for screening. Setting and conduct: Belgaum district which is a Category ‘A’ district (with more than 1 % antenatal prevalence in the district over the last 3 years before the study. Age-appropriate testing is used to detect HIV infection. Discussion There is a need to strengthen

  6. Research protocol for an epidemiological study on estimating disease burden of pediatric HIV in Belgaum district, India.

    Science.gov (United States)

    Sinha, Anju; Nath, Anita; Sethumadhavan, Rajeev; Isac, Shajy; Washington, Reynold

    2016-05-26

    Pediatric HIV is poised to become a major public health problem in India with the rising trend of HIV infection in pregnant women (Department of AIDS Control, Ministry of Health and Family Welfare, http://www.naco.gov.in). There is lack of information on the epidemiology of pediatric HIV infection in India. Existing surveillance systems tend to underestimate the Pediatric burden. The overall aim of the present study is to estimate the disease burden of pediatric HIV among children in Belgaum district in the state of Karnataka in Southern India. An innovative multipronged epidemiological approach to comb the district is proposed. The primary objectives of the study would be attained under three strategies. A prospective cohort design for objective (i) to determine the incidence rate of HIV by early case detection in infants and toddlers (0-18 months) born to HIV infected pregnant women; and cross sectional design for objectives (ii) to determine the prevalence of HIV infection in children (0-14 years) of HIV infected parents and (iii) to determine the prevalence of HIV in sick children (0-14 years) presenting with suspected signs and symptoms using age specific criteria for screening. Burden of pediatric HIV will be calculated as a product of cases detected in each strategy multiplied by a net inflation factor for each strategy. Study participants (i) (ii) (iii): HIV infected pregnant women and their live born children (ii) Any HIV-infected man/woman, of age 18-49 years, having a biological child of age 0-14 years (iii) Sick children of age 0-14 years presenting with suspected signs and symptoms and satisfying age-specific criteria for screening. Setting and conduct: Belgaum district which is a Category 'A' district (with more than 1 % antenatal prevalence in the district over the last 3 years before the study). Age-appropriate testing is used to detect HIV infection. There is a need to strengthen existing pediatric HIV estimation methods in India and other

  7. Using focus groups in the consumer research phase of a social marketing program to promote moderate-intensity physical activity and walking trail use in Sumter County, South Carolina.

    Science.gov (United States)

    Burroughs, Ericka; Peck, Lara E; Sharpe, Patricia A; Granner, Michelle L; Bryant, Carol A; Fields, Regina

    2006-01-01

    The use of social marketing approaches in public health practice is increasing. Using marketing concepts such as the "four Ps" (product, price, place, and promotion), social marketing borrows from the principles of commercial marketing but promotes beneficial health behaviors. Consumer research is used to segment the population and develop a strategy based on those marketing concepts. In a community-based participatory research study, 17 focus groups were used in consumer research to develop a social marketing program to promote walking and other moderate-intensity physical activities. Two phases of focus groups were conducted. Phase 1 groups, which included both men and women, were asked to respond to questions that would guide the development of a social marketing program based on social marketing concepts. Phase 1 also determined the intervention's target audience, which was irregularly active women aged 35 to 54. Phase 2 groups, composed of members of the target audience, were asked to further define the product and discuss specific promotion strategies. Phase 1 participants determined that the program product, or target behavior, should be walking. In addition, they identified price, place, and promotion strategies. Phase 2 participants determined that moderate-intensity physical activity is best promoted using the term exercise and offered suggestions for marketing walking, or exercise, to the target audience. There have been few published studies of social marketing campaigns to promote physical activity. In this study, focus groups were key to understanding the target audience in a way that would not have been accomplished with quantitative data alone. The group discussions generated important insights into values and motivations that affect consumers' decisions to adopt a product or behavior. The focus group results guided the development of a social marketing program to promote physical activity in the target audience in Sumter County, South Carolina.

  8. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-03-02

    Mar 2, 2015 ... Joseph Daniels1,&, Ruth Nduati1,2, James Kiarie1,3, Carey Farquhar1,4,5 .... or basic science research career (Socio-Behavioral Research, .... a research environment that supports knowledge sharing to develop research ...

  9. A Bayesian approach to unanticipated events frequency estimation in the decision making context of a nuclear research reactor facility

    International Nuclear Information System (INIS)

    Chatzidakis, S.; Staras, A.

    2013-01-01

    Highlights: • The Bayes’ theorem is employed to support the decision making process in a research reactor. • The intention is to calculate parameters related to unanticipated occurrence of events. • Frequency, posterior distribution and confidence limits are calculated. • The approach is demonstrated using two real-world numerical examples. • The approach can be used even if no failures have been observed. - Abstract: Research reactors are considered as multi-tasking environments having the multiple roles of commercial, research and training facilities. Yet, reactor managers have to make decisions, frequently with high economic impact, based on little available knowledge. A systematic approach employing the Bayes’ theorem is proposed to support the decision making process in a research reactor environment. This approach is characterized by low level complexity, appropriate for research reactor facilities. The methodology is demonstrated through the study of two characteristic events that lead to unanticipated system shutdown, namely the de-energization of the control rod magnet and the flapper valve opening. The results obtained demonstrate the suitability of the Bayesian approach in the decision making context when unanticipated events are considered

  10. Research

    African Journals Online (AJOL)

    ebutamanya

    2016-06-10

    Jun 10, 2016 ... for an estimated 16 million people resident in the state. The facility ... Summary data is ... Mediastinal lymphadenopathy can either be due to malignant or .... appropriate therapy be instituted as opposed to blind therapy [4].

  11. Research

    African Journals Online (AJOL)

    abp

    2016-06-09

    Jun 9, 2016 ... trachoma by nurse data collectors supervised by ophthalmic supervisors using the WHO simplified clinical .... determining the sample size, we estimated the prevalence of ..... Their argument was that flies may breed on animal.

  12. Research

    African Journals Online (AJOL)

    abp

    2017-09-14

    Sep 14, 2017 ... from 2006–2014 is $400.0 million-$2.4 billion, resulting in an economic gain of $10,732-$63,949 per CLP patient (Table 3). Considering an estimated total cost of US$13,045,900 and between. $400.0 million-$2.4 billion economic gain using the VSL approach, the estimated BCR ranges from 30.1-184.

  13. Research

    African Journals Online (AJOL)

    abp

    2016-03-30

    Mar 30, 2016 ... 1School of Public Health, University of Alberta, Edmonton, Alberta, Canada, 2Aga Khan .... “Focus on Opportunity, Ability and Motivation” (FOAM) framework ... children (-28%), before eating (-4%), and after attending to a child.

  14. Research

    African Journals Online (AJOL)

    abp

    2013-08-08

    Aug 8, 2013 ... Preconception genetic screening and counselling should be the main focus of .... important variable that influences the acceptability, practice and success of ... attention. Study done among health care workers and medical.

  15. Trends and Recent Estimates: Contraceptive Use among U.S. Teens. Child Trends Research Brief. Publication #2006-04

    Science.gov (United States)

    Franzetta, Kerry; Terry-Humen, Elizabeth; Manlove, Jennifer; Ikramullah, Erum

    2006-01-01

    This Research Brief draws on recently released nationally representative data to provide information on teenagers' patterns of contraceptive use during heterosexual, vaginal intercourse. In this brief, the authors examine these patterns for males and females, for members of racial and ethnic groups, and for younger and older teenagers. Among the…

  16. Turnover in Principalship Focus of Research

    Science.gov (United States)

    Viadero, Debra

    2009-01-01

    Data available from a handful of states suggest that only about half of beginning principals remain in the same job five years later, and that many leave the principalship altogether when they go. Whether this apparent churn in the principal's office signals a problem, progress, or business as usual seems to be a matter for debate, though. Among…

  17. Four Dimensions of Brand-Focused Research

    Science.gov (United States)

    Lischick, Caity McLaughlin

    2017-01-01

    Not long ago, "brand" was an unmentionable word in the higher education landscape--one that came with suspicious connotations of consumer packaged goods and retail. Today, however, there is increasingly broad acceptance that a higher education institution's (HEI's) brand is critical to attracting and retaining the best students and…

  18. Plutonium focus area. Technology summary

    International Nuclear Information System (INIS)

    1997-09-01

    The Assistant Secretary for the Office of Environmental Management (EM) at the U.S. Department of Energy (DOE) chartered the Plutonium Focus Area (PFA) in October 1995. The PFA open-quotes...provides for peer and technical reviews of research and development in plutonium stabilization activities...close quotes In addition, the PFA identifies and develops relevant research and technology. The purpose of this document is to focus attention on the requirements used to develop research and technology for stabilization, storage, and preparation for disposition of nuclear materials. The PFA Technology Summary presents the approach the PFA uses to identify, recommend, and review research. It lists research requirements, research being conducted, and gaps where research is needed. It also summarizes research performed by the PFA in the traditional research summary format. This document encourages researchers and commercial enterprises to do business with PFA by submitting research proposals or open-quotes white papers.close quotes In addition, it suggests ways to increase the likelihood that PFA will recommend proposed research to the Nuclear Materials Stabilization Task Group (NMSTG) of DOE

  19. Research

    African Journals Online (AJOL)

    A descriptive qualitative research design was used to determine whether participants ... simulation as a teaching method; a manikin offering effective learning; confidence ..... Tesch R. Qualitative Research: Analysis Types and Software Tools.

  20. Characteristics of neutron irradiation facility and dose estimation method for neutron capture therapy at Kyoto University research reactor institute

    International Nuclear Information System (INIS)

    Kobayashi, T.; Sakurai, Y.; Kanda, K.

    2001-01-01

    The neutron irradiation characteristics of the Heavy Water Neutron Irradiation Facility (HWNIF) at the Kyoto University Research Reactor Institute (KIJRRI) for boron neutron capture therapy (BNCT), is described. The present method of dose measurement and its evaluation at the KURRI, is explained. Especially, the special feature and noticeable matters were expounded for the BNCT with craniotomy, which has been applied at present only in Japan. (author)