WorldWideScience

Sample records for research findings point

  1. Finding a single point of truth

    Energy Technology Data Exchange (ETDEWEB)

    Sokolov, S.; Thijssen, H. [Autodesk Inc, Toronto, ON (Canada); Laslo, D.; Martin, J. [Autodesk Inc., San Rafael, CA (United States)

    2010-07-01

    Electric utilities collect large volumes of data at every level of their business, including SCADA, Smart Metering and Smart Grid initiatives, LIDAR and other 3D imagery surveys. Different types of database systems are used to store the information, rendering data flow within the utility business process extremely complicated. The industry trend has been to endure redundancy of data input and maintenance of multiple copies of the same data across different solution data sets. Efforts have been made to improve the situation with point to point interfaces, but with the tools and solutions available today, a single point of truth can be achieved. Consolidated and validated data can be published into a data warehouse at the right point in the process, making the information available to all other enterprise systems and solutions. This paper explained how the single point of truth spatial data warehouse and process automation services can be configured to streamline the flow of data within the utility business process using the initiate-plan-execute-close (IPEC) utility workflow model. The paper first discussed geospatial challenges faced by utilities and then presented the approach and technology aspects. It was concluded that adoption of systems and solutions that can function with and be controlled by the IPEC workflow can provide significant improvement for utility operations, particularly if those systems are coupled with the spatial data warehouse that reflects a single point of truth. 6 refs., 3 figs.

  2. Knowledge translation of research findings

    Directory of Open Access Journals (Sweden)

    Grimshaw Jeremy M

    2012-05-01

    Full Text Available Abstract Background One of the most consistent findings from clinical and health services research is the failure to translate research into practice and policy. As a result of these evidence-practice and policy gaps, patients fail to benefit optimally from advances in healthcare and are exposed to unnecessary risks of iatrogenic harms, and healthcare systems are exposed to unnecessary expenditure resulting in significant opportunity costs. Over the last decade, there has been increasing international policy and research attention on how to reduce the evidence-practice and policy gap. In this paper, we summarise the current concepts and evidence to guide knowledge translation activities, defined as T2 research (the translation of new clinical knowledge into improved health. We structure the article around five key questions: what should be transferred; to whom should research knowledge be transferred; by whom should research knowledge be transferred; how should research knowledge be transferred; and, with what effect should research knowledge be transferred? Discussion We suggest that the basic unit of knowledge translation should usually be up-to-date systematic reviews or other syntheses of research findings. Knowledge translators need to identify the key messages for different target audiences and to fashion these in language and knowledge translation products that are easily assimilated by different audiences. The relative importance of knowledge translation to different target audiences will vary by the type of research and appropriate endpoints of knowledge translation may vary across different stakeholder groups. There are a large number of planned knowledge translation models, derived from different disciplinary, contextual (i.e., setting, and target audience viewpoints. Most of these suggest that planned knowledge translation for healthcare professionals and consumers is more likely to be successful if the choice of knowledge

  3. Knowledge translation of research findings.

    Science.gov (United States)

    Grimshaw, Jeremy M; Eccles, Martin P; Lavis, John N; Hill, Sophie J; Squires, Janet E

    2012-05-31

    One of the most consistent findings from clinical and health services research is the failure to translate research into practice and policy. As a result of these evidence-practice and policy gaps, patients fail to benefit optimally from advances in healthcare and are exposed to unnecessary risks of iatrogenic harms, and healthcare systems are exposed to unnecessary expenditure resulting in significant opportunity costs. Over the last decade, there has been increasing international policy and research attention on how to reduce the evidence-practice and policy gap. In this paper, we summarise the current concepts and evidence to guide knowledge translation activities, defined as T2 research (the translation of new clinical knowledge into improved health). We structure the article around five key questions: what should be transferred; to whom should research knowledge be transferred; by whom should research knowledge be transferred; how should research knowledge be transferred; and, with what effect should research knowledge be transferred? We suggest that the basic unit of knowledge translation should usually be up-to-date systematic reviews or other syntheses of research findings. Knowledge translators need to identify the key messages for different target audiences and to fashion these in language and knowledge translation products that are easily assimilated by different audiences. The relative importance of knowledge translation to different target audiences will vary by the type of research and appropriate endpoints of knowledge translation may vary across different stakeholder groups. There are a large number of planned knowledge translation models, derived from different disciplinary, contextual (i.e., setting), and target audience viewpoints. Most of these suggest that planned knowledge translation for healthcare professionals and consumers is more likely to be successful if the choice of knowledge translation strategy is informed by an assessment of the

  4. Researchers Find a Mechanism for Schizophrenia

    Science.gov (United States)

    ... issue Health Capsule Researchers Find a Mechanism for Schizophrenia En español Send us your comments Scientists uncovered a mechanism behind genetic variations previously linked to schizophrenia. The findings may lead to new clinical approaches. ...

  5. Sharing Research Findings with Research Participants and Communities

    Directory of Open Access Journals (Sweden)

    LE Ferris

    2011-06-01

    Full Text Available In occupational and environmental health research, individual, group and community research participants have a unique and vested interest in the research findings. The ethical principles of autonomy, non-maleficence and beneficence are helpful in considering the ethical issues in the disclosure of research findings in occupational and environmental health research. Researchers need to include stakeholders, such as groups and communities, in these discussions and in planning for the dissemination of research findings. These discussions need to occur early in the research process.

  6. 77 FR 38632 - Findings of Research Misconduct

    Science.gov (United States)

    2012-06-28

    ... Institute on Drug Abuse (NIDA), NIH. ORI found that the Respondent engaged in research misconduct by... animal model of Parkinson's disease, 2006 (``manuscript''). Specifically, ORI finds that the Respondent...

  7. FINDING CUBOID-BASED BUILDING MODELS IN POINT CLOUDS

    Directory of Open Access Journals (Sweden)

    W. Nguatem

    2012-07-01

    Full Text Available In this paper, we present an automatic approach for the derivation of 3D building models of level-of-detail 1 (LOD 1 from point clouds obtained from (dense image matching or, for comparison only, from LIDAR. Our approach makes use of the predominance of vertical structures and orthogonal intersections in architectural scenes. After robustly determining the scene's vertical direction based on the 3D points we use it as constraint for a RANSAC-based search for vertical planes in the point cloud. The planes are further analyzed to segment reliable outlines for rectangular surface within these planes, which are connected to construct cuboid-based building models. We demonstrate that our approach is robust and effective over a range of real-world input data sets with varying point density, amount of noise, and outliers.

  8. 77 FR 22320 - Findings of Research Misconduct

    Science.gov (United States)

    2012-04-13

    ... have injected retinal pigment epithelial (RPE) cells obtained from Rhesus monkey embryonic stem cells... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Findings of Research Misconduct... Research Integrity (ORI) has taken final action in the following case: Peter J. Francis, M.D., Ph.D...

  9. FIND: Douglas Point Nuclear Generating Station, Units 1 and 2

    International Nuclear Information System (INIS)

    Moore, M.M.

    1975-12-01

    This index is presented as a guide to microfiche items 1 through 136 in Docket 50448, which was assigned to Potomac Electric Power Company's Application for Licenses to construct and operate Douglas Point Nuclear Generating Station, Units 1 and 2. Information received from August, 1973 through July, 1975 is included

  10. An algebraic approach to finding the Fermat-Torricelli point

    Science.gov (United States)

    Palacios-Vélez, Óscar Luis; Pedraza-Oropeza, Felipe J. A.; Escobar-Villagran, Bernardo Samuel

    2015-11-01

    Using a calculus and an algebraic approach, the Cartesian coordinates of the Fermat-Torricelli point are deduced for triangles with no internal angle greater than 120°. Although in theory, the deduction of these coordinates could be made 'by hand', in practice it is very laborious to obtain them without the aid of mathematical computer software, but with human guidance, since there are mathematical artifices not yet incorporated into the software. It is also shown that these coordinates can be conveniently expressed in terms of the side lengths and the area of the triangle. These coordinates are contrasted with the coordinates of a similar point: one whose sum of the squares of the distances to the vertices of an arbitrary triangle is a minimum.

  11. Individual patient data analysis of progression-free survival versus overall survival as a first-line end point for metastatic colorectal cancer in modern randomized trials: findings from the analysis and research in cancers of the digestive system database.

    Science.gov (United States)

    Shi, Qian; de Gramont, Aimery; Grothey, Axel; Zalcberg, John; Chibaudel, Benoist; Schmoll, Hans-Joachim; Seymour, Matthew T; Adams, Richard; Saltz, Leonard; Goldberg, Richard M; Punt, Cornelis J A; Douillard, Jean-Yves; Hoff, Paulo M; Hecht, Joel Randolph; Hurwitz, Herbert; Díaz-Rubio, Eduardo; Porschen, Rainer; Tebbutt, Niall C; Fuchs, Charles; Souglakos, John; Falcone, Alfredo; Tournigand, Christophe; Kabbinavar, Fairooz F; Heinemann, Volker; Van Cutsem, Eric; Bokemeyer, Carsten; Buyse, Marc; Sargent, Daniel J

    2015-01-01

    Progression-free survival (PFS) has previously been established as a surrogate for overall survival (OS) for first-line metastatic colorectal cancer (mCRC). Because mCRC treatment has advanced in the last decade with extended OS, this surrogacy requires re-examination. Individual patient data from 16,762 patients were available from 22 first-line mCRC studies conducted from 1997 to 2006; 12 of those studies tested antiangiogenic and/or anti-epidermal growth factor receptor agents. The relationship between PFS (first event of progression or death) and OS was evaluated by using R(2) statistics (the closer the value is to 1, the stronger the correlation) from weighted least squares regression of trial-specific hazard ratios estimated by using Cox and Copula models. Forty-four percent of patients received a regimen that included biologic agents. Median first-line PFS was 8.3 months, and median OS was 18.2 months. The correlation between PFS and OS was modest (R(2), 0.45 to 0.69). Analyses limited to trials that tested treatments with biologic agents, nonstrategy trials, or superiority trials did not improve surrogacy. In modern mCRC trials, in which survival after the first progression exceeds time to first progression, a positive but modest correlation was observed between OS and PFS at both the patient and trial levels. This finding demonstrates the substantial variability in OS introduced by the number of lines of therapy and types of effective subsequent treatments and the associated challenge to the use of OS as an end point to assess the benefit attributable to a single line of therapy. PFS remains an appropriate primary end point for first-line mCRC trials to detect the direct treatment effect of new agents. © 2014 by American Society of Clinical Oncology.

  12. What is access – finding the nearest possible vantage point?

    DEFF Research Database (Denmark)

    Gaborit, Liv Stoltze

    Access is an issue often discussed in prison research. These discussions often revolve around the issue of getting permission to enter prisons or certain areas of prisons. This paper argues for expanding the ways we think about access....

  13. 77 FR 54917 - Findings of Research Misconduct

    Science.gov (United States)

    2012-09-06

    ... monkeys were able to understand communicative gestures performed by a human. Specifically, (1) in the... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Findings of Research Misconduct... RR003640-13, National Institute on Deafness and Other Communication Disorders (NIDCD), NIH, grant 5 R01...

  14. 77 FR 69627 - Findings of Research Misconduct

    Science.gov (United States)

    2012-11-20

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Findings of Research Misconduct... Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH, grant R56 DK063025, and National... Physiol. 291(6):C1271-8, 2006 Am J. Physiol. Cell Physiol. 294(1):C295-305, 2008 J. Lipid Res. 42:1444...

  15. 78 FR 21125 - Findings of Research Misconduct

    Science.gov (United States)

    2013-04-09

    ... compared to wild type NE in Figure 4A, NEM, Figure 6A, CMA, Figure 8, HL73063-01, and Figure 7, HL79615-01.... Respondent agreed not to appeal the ORI findings of research misconduct set forth above. He has agreed...

  16. 78 FR 8148 - Findings of Research Misconduct

    Science.gov (United States)

    2013-02-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Findings of Research Misconduct AGENCY: Office of the Secretary, HHS. ACTION: Notice. SUMMARY: Notice is hereby given that the Office of... Philosophy, August 2009; hereafter referred to as the ``Dissertation.'' Doreian, B.W., Fulop, T.G...

  17. 75 FR 39530 - Findings of Research Misconduct

    Science.gov (United States)

    2010-07-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Findings of Research Misconduct... retinal gene profile data that he purportedly obtained from three-week old normal dogs and dogs with X... normal dogs and dogs with X-linked progressive retinal atrophy in abstracts and poster presentations for...

  18. Finding Exoplanets Using Point Spread Function Photometry on Kepler Data

    Science.gov (United States)

    Amaro, Rachael Christina; Scolnic, Daniel; Montet, Ben

    2018-01-01

    The Kepler Mission has been able to identify over 5,000 exoplanet candidates using mostly aperture photometry. Despite the impressive number of discoveries, a large portion of Kepler’s data set is neglected due to limitations using aperture photometry on faint sources in crowded fields. We present an alternate method that overcomes those restrictions — Point Spread Function (PSF) photometry. This powerful tool, which is already used in supernova astronomy, was used for the first time on Kepler Full Frame Images, rather than just looking at the standard light curves. We present light curves for stars in our data set and demonstrate that PSF photometry can at least get down to the same photometric precision as aperture photometry. As a check for the robustness of this method, we change small variables (stamp size, interpolation amount, and noise correction) and show that the PSF light curves maintain the same repeatability across all combinations for one of our models. We also present our progress in the next steps of this project, including the creation of a PSF model from the data itself and applying the model across the entire data set at once.

  19. 77 FR 5254 - Findings of Research Misconduct

    Science.gov (United States)

    2012-02-02

    ..., former Research Assistant and Data Base Manager, CU, engaged in research misconduct in research funded by... present responsibility to be a steward of Federal funds. 2 CFR 180.125, 180.800(d), 376.10. The following...

  20. 77 FR 32116 - Findings of Research Misconduct

    Science.gov (United States)

    2012-05-31

    ..., R. Thomas, D. Neil Hayes, M. Meyerson, D.J. Kwiatkowski, and K.-K. Wong, submitted to the Journal of... supervisory plan must be designed to ensure the scientific integrity of his research contribution; Respondent... application for PHS funds or any report, manuscript, or abstract of PHS-funded research in which he is...

  1. 75 FR 77641 - Findings of Research Misconduct

    Science.gov (United States)

    2010-12-13

    ... significance, used to calculate repression ratios and RNA decay rates. Dr. Mungekar also claimed to have... proposed or that uses him in any capacity on PHS-supported research, or that submits a report of PHS-funded...

  2. 78 FR 67363 - Findings of Research Misconduct

    Science.gov (United States)

    2013-11-12

    ... University--Canada (formerly University of Western Ontario): Based on the report of an investigation conducted by Western University--Canada (WU) and ORI's subsequent oversight analysis, ORI found that Dr. Hao...-supported research, Respondent shall ensure that a plan for supervision of his duties is submitted to ORI...

  3. 77 FR 52034 - Findings of Research Misconduct

    Science.gov (United States)

    2012-08-28

    ... fellow, Department of Developmental and Stem Cell Biology, Joslin, engaged in research misconduct in... regulate ageing and rejuventation of blood stem cell niches.'' Nature 463:495-500, 2010. Mayack, S.R., & Wagers, A.J. ``Osteolineage niche cells initiate hemotopoietic stem cell mobilization.'' Blood 112:519...

  4. 77 FR 40059 - Findings of Research Misconduct

    Science.gov (United States)

    2012-07-06

    ... experimental results from her prior work in Korea with human embryonic stem cells (hESCs) to confirm the generation, differentiation, and verification of human induced pluripotent stem cells (iPSCs). The false data...--121508.ppt' 5. Falsified research materials when the Respondent distributed cells to laboratory members...

  5. 75 FR 18836 - Findings of Research Misconduct

    Science.gov (United States)

    2010-04-13

    ... case: Emily M. Horvath, Indiana University: Based on the Respondent's own admissions in sworn testimony... National Center for Complementary and Alternative Medicine (NCCAM), National Institutes of Health (NIH... admitted to falsifying the original research data when entering values into computer programs for...

  6. DIAGNOSTIC FEATURES RESEARCH OF AC ELECTRIC POINT MOTORS

    Directory of Open Access Journals (Sweden)

    S. YU. Buryak

    2014-05-01

    Full Text Available Purpose.Considerable responsibility for safety of operation rests on signal telephone and telegraph department of railway. One of the most attackable nodes (both automation systems, and railway in whole is track switches. The aim of this investigation is developing such system for monitoring and diagnostics of track switches, which would fully meet the requirements of modern conditions of high-speed motion and heavy trains and producing diagnostics, collection and systematization of data in an automated way. Methodology. In order to achieve the desired objectives research of a structure and the operating principle description of the switch electric drive, sequence of triggering its main units were carried out. The operating characteristics and settings, operating conditions, the causes of failures in the work, andrequirements for electric drives technology and their service were considered and analyzed. Basic analysis principles of dependence of nature of the changes the current waveform, which flows in the working circuit of AC electric point motor were determined. Technical implementation of the monitoring and diagnosing system the state of AC electric point motors was carried out. Findings. Signals taken from serviceable and defective electric turnouts were researched. Originality. Identified a strong interconnectionbetween the technical condition of the track switchand curve shape that describes the current in the circuit of AC electric point motor during operation which is based on the research processes that have influence on it during operation. Practical value. Shown the principles of the technical approach to the transition from scheduled preventive maintenance to maintenance of real condition for a more objective assessment and thus more rapid response to emerging or failures when they occur gradually, damages and any other shortcomings in the work track switch AC drives.

  7. Translational findings from cardiovascular stem cell research.

    Science.gov (United States)

    Mazhari, Ramesh; Hare, Joshua M

    2012-01-01

    The possibility of using stem cells to regenerate damaged myocardium has been actively investigated since the late 1990s. Consistent with the traditional view that the heart is a "postmitotic" organ that possesses minimal capacity for self-repair, much of the preclinical and clinical work has focused exclusively on introducing stem cells into the heart, with the hope of differentiation of these cells into functioning cardiomyocytes. This approach is ongoing and retains promise but to date has yielded inconsistent successes. More recently, it has become widely appreciated that the heart possesses endogenous repair mechanisms that, if adequately stimulated, might regenerate damaged cardiac tissue from in situ cardiac stem cells. Accordingly, much recent work has focused on engaging and enhancing endogenous cardiac repair mechanisms. This article reviews the literature on stem cell-based myocardial regeneration, placing emphasis on the mutually enriching interaction between basic and clinical research. Copyright © 2012 Elsevier Inc. All rights reserved.

  8. Open Data in Global Environmental Research: Findings from the Community

    Energy Technology Data Exchange (ETDEWEB)

    Van Honk, J.; Calero-Medina, C.; Costas, R.

    2016-07-01

    This paper presents findings from the Belmont Forum’s survey on Open Data which targeted the global environmental research and data infrastructure community (Schmidt, Gemeinholzer & Treloar, 2016). It highlights users’ perceptions of the term “open data”, expectations of infrastructure functionalities, and barriers and enablers for the sharing of data. A wide range of good practice examples was pointed out by the respondents which demonstrates a substantial uptake of data sharing through e-infrastructures and a further need for enhancement and consolidation. Among all policy responses, funder policies seem to be the most important motivator. This supports the conclusion that stronger mandates will strengthen the case for data sharing. The Belmont Forum, a group of high-level representatives from major funding agencies across the globe, coordinates funding for collaborative research to address the challenges and opportunities of global environmental change. In particular, the E-Infrastructure and Data Management Collaborative Research Action has brought together domain scientists, computer and information scientists, legal scholars, social scientists, and other experts from more than 14 countries to establish recommendations on how the Belmont Forum can implement a more coordinated, holistic, and sustainable approach to the funding and support of global environmental change research. (Author)

  9. Establishing the credibility of qualitative research findings: the plot thickens.

    Science.gov (United States)

    Cutcliffe, J R; McKenna, H P

    1999-08-01

    Qualitative research is increasingly recognized and valued and its unique place in nursing research is highlighted by many. Despite this, some nurse researchers continue to raise epistemological issues about the problems of objectivity and the validity of qualitative research findings. This paper explores the issues relating to the representativeness or credibility of qualitative research findings. It therefore critiques the existing distinct philosophical and methodological positions concerning the trustworthiness of qualitative research findings, which are described as follows: quantitative studies should be judged using the same criteria and terminology as quantitative studies; it is impossible, in a meaningful way, for any criteria to be used to judge qualitative studies; qualitative studies should be judged using criteria that are developed for and fit the qualitative paradigm; and the credibility of qualitative research findings could be established by testing out the emerging theory by means of conducting a deductive quantitative study. The authors conclude by providing some guidelines for establishing the credibility of qualitative research findings.

  10. Helping Teachers Use Research Findings: The Consumer-Validation Process.

    Science.gov (United States)

    Eaker, Robert E.; Huffman, James O.

    A program stressing teacher involvement and classroom implementation of educational research findings is described. The program was designed to familiarize teachers with current findings, have them apply the findings in their classrooms, analyze their own teaching behavior, and critically evaluate the findings in terms of their applicability to…

  11. 77 FR 25131 - Turning Point Solar LLC: Notice of Finding of No Significant Impact

    Science.gov (United States)

    2012-04-27

    ... monocrystalline photovoltaic panels mounted on fixed solar racking equipment and the construction of access roads... DEPARTMENT OF AGRICULTURE Rural Utilities Service Turning Point Solar LLC: Notice of Finding of No... Environmental Assessment (EA) associated with a solar generation project. The EA was prepared in accordance with...

  12. Grade point average and biographical data in personal resumes: Predictors of finding employment

    NARCIS (Netherlands)

    Sulastri, A.; Handoko, M.; Janssens, J.M.A.M.

    2015-01-01

    This study aimed to examine relationships between graduates' grade point average (GPA), biographical data and success in finding a job in general and a psychology-based job in particular. Two hundred six psychology graduates participated in a two-wave longitudinal study. Biographical data assessed

  13. NIH Researchers Find Potential Genetic Cause of Cushing Syndrome

    Science.gov (United States)

    ... 2017 NIH researchers find potential genetic cause of Cushing syndrome Finding may lead to therapies that prevent pituitary ... mutations in the gene CABLES1 may lead to Cushing syndrome, a rare disorder in which the body overproduces ...

  14. Surrogate end points in clinical research: hazardous to your health.

    Science.gov (United States)

    Grimes, David A; Schulz, Kenneth F

    2005-05-01

    Surrogate end points in clinical research pose real danger. A surrogate end point is an outcome measure, commonly a laboratory test, that substitutes for a clinical event of true importance. Resistance to activated protein C, for example, has been used as a surrogate for venous thrombosis in women using oral contraceptives. Other examples of inappropriate surrogate end points in contraception include the postcoital test instead of pregnancy to evaluate new spermicides, breakage and slippage instead of pregnancy to evaluate condoms, and bone mineral density instead of fracture to assess the safety of depo-medroxyprogesterone acetate. None of these markers captures the effect of the treatment on the true outcome. A valid surrogate end point must both correlate with and accurately predict the outcome of interest. Although many surrogate markers correlate with an outcome, few have been shown to capture the effect of a treatment (for example, oral contraceptives) on the outcome (venous thrombosis). As a result, thousands of useless and misleading reports on surrogate end points litter the medical literature. New drugs have been shown to benefit a surrogate marker, but, paradoxically, triple the risk of death. Thousands of patients have died needlessly because of reliance on invalid surrogate markers. Researchers should avoid surrogate end points unless they have been validated; that requires at least one well done trial using both the surrogate and true outcome. The clinical maxim that "a difference to be a difference must make a difference" applies to research as well. Clinical research should focus on outcomes that matter.

  15. The Value of Surprising Findings for Research on Marketing

    OpenAIRE

    JS Armstrong

    2004-01-01

    In the work of Armstrong (Journal of Business Research, 2002), I examined empirical research on the scientific process and related these to marketing science. The findings of some studies were surprising. In this reply, I address surprising findings and other issues raised by commentators.

  16. Using the Chandra Source-Finding Algorithm to Automatically Identify Solar X-ray Bright Points

    Science.gov (United States)

    Adams, Mitzi L.; Tennant, A.; Cirtain, J. M.

    2009-01-01

    This poster details a technique of bright point identification that is used to find sources in Chandra X-ray data. The algorithm, part of a program called LEXTRCT, searches for regions of a given size that are above a minimum signal to noise ratio. The algorithm allows selected pixels to be excluded from the source-finding, thus allowing exclusion of saturated pixels (from flares and/or active regions). For Chandra data the noise is determined by photon counting statistics, whereas solar telescopes typically integrate a flux. Thus the calculated signal-to-noise ratio is incorrect, but we find we can scale the number to get reasonable results. For example, Nakakubo and Hara (1998) find 297 bright points in a September 11, 1996 Yohkoh image; with judicious selection of signal-to-noise ratio, our algorithm finds 300 sources. To further assess the efficacy of the algorithm, we analyze a SOHO/EIT image (195 Angstroms) and compare results with those published in the literature (McIntosh and Gurman, 2005). Finally, we analyze three sets of data from Hinode, representing different parts of the decline to minimum of the solar cycle.

  17. "Response to Comments": Finding the Narrative in Narrative Research

    Science.gov (United States)

    Coulter, Cathy A.

    2009-01-01

    The author responds to comments by Barone (2009), Clandinin and Murphy (2009), and M. W. Smith (2009) on "The Construction Zone: Literary Elements in Narrative Research" (Coulter & M. L. Smith, 2009). She clarifies issues regarding point of view, authorial surplus, narrative coherence, and the relational qualities of narrative research. She…

  18. Managing incidental findings in human subjects research: analysis and recommendations.

    Science.gov (United States)

    Wolf, Susan M; Lawrenz, Frances P; Nelson, Charles A; Kahn, Jeffrey P; Cho, Mildred K; Clayton, Ellen Wright; Fletcher, Joel G; Georgieff, Michael K; Hammerschmidt, Dale; Hudson, Kathy; Illes, Judy; Kapur, Vivek; Keane, Moira A; Koenig, Barbara A; Leroy, Bonnie S; McFarland, Elizabeth G; Paradise, Jordan; Parker, Lisa S; Terry, Sharon F; Van Ness, Brian; Wilfond, Benjamin S

    2008-01-01

    No consensus yet exists on how to handle incidental findings (IFs) in human subjects research. Yet empirical studies document IFs in a wide range of research studies, where IFs are findings beyond the aims of the study that are of potential health or reproductive importance to the individual research participant. This paper reports recommendations of a two-year project group funded by NIH to study how to manage IFs in genetic and genomic research, as well as imaging research. We conclude that researchers have an obligation to address the possibility of discovering IFs in their protocol and communications with the IRB, and in their consent forms and communications with research participants. Researchers should establish a pathway for handling IFs and communicate that to the IRB and research participants. We recommend a pathway and categorize IFs into those that must be disclosed to research participants, those that may be disclosed, and those that should not be disclosed.

  19. APPLYING RESEARCH FINDINGS IN COMPREHENSION TO CLASSROOM PRACTICE.

    Science.gov (United States)

    WILLIAMS, RICHARD P.

    RESEARCH SHOWS THAT, IN SPITE OF THE FAVORABLE ATTITUDE TOWARD SCIENTIFIC RESEARCH, A GAP EXISTS BETWEEN THE INITIATION OF AN INNOVATION AND ITS WIDE ACCEPTANCE. TO HELP CLOSE THE GAP, TEACHERS ARE ENCOURAGED TO APPLY RESEARCH FINDINGS TO CLASSROOM PRACTICE AND TO DETERMINE THEIR FEASIBILITY. SIXTEEN STUDIES ON COMPREHENSION CITED IN THIS ARTICLE…

  20. African elephants can use human pointing cues to find hidden food.

    Science.gov (United States)

    Smet, Anna F; Byrne, Richard W

    2013-10-21

    How animals gain information from attending to the behavior of others has been widely studied, driven partly by the importance of referential pointing in human cognitive development [1-4], but species differences in reading human social cues remain unexplained. One explanation is that this capacity evolved during domestication [5, 6], but it may be that only those animals able to interpret human-like social cues were successfully domesticated. Elephants are a critical taxon for this question: despite their longstanding use by humans, they have never been domesticated [7]. Here we show that a group of 11 captive African elephants, seven of them significantly as individuals, could interpret human pointing to find hidden food. We suggest that success was not due to prior training or extensive learning opportunities. Elephants successfully interpreted pointing when the experimenter's proximity to the hiding place was varied and when the ostensive pointing gesture was visually subtle, suggesting that they understood the experimenter's communicative intent. The elephant's native ability in interpreting social cues may have contributed to its long history of effective use by man. Copyright © 2013 Elsevier Ltd. All rights reserved.

  1. Do Students Eventually Get to Publish their Research Findings? The ...

    African Journals Online (AJOL)

    research findings to other scientist and to advance scientific discovery. ... publication in a scientific journal with a total of 22 journal articles, giving a mean publication rate of 0.17 ..... publication and advice policy on the necessary actions to.

  2. Social Science Research Findings and Educational Policy Dilemmas

    Directory of Open Access Journals (Sweden)

    Steven I. Miller

    2000-01-01

    Full Text Available The article attempts to raise several distinctions regarding the presumed relationship of social science research findings to social policy making. The distinctions are made using Glymour's critique of the Bell Curve. An argument is made that (1 social science models and research findings are largely irrelevant to the actual concerns of policy makers and (2 what is relevant, but overlooked by Glymour, is how ideological factors mediate the process. The forms that ideological mediation may take are indicated.

  3. Multiple Perpetrator Rape: Naming an Offence and Initial Research Findings

    Science.gov (United States)

    Horvath, Miranda Angel Helena; Kelly, Liz

    2009-01-01

    Multiple perpetrator rape presents a significant problem nationally and internationally. However, previous research is limited and findings are often contradictory. The details of 101 rape allegations recorded in a six-month period in a large police force in England were analysed. Findings are presented about case classification, victim and…

  4. "Atmospheric Radiation Measurement (ARM) Research Facility at Oliktok Point Alaska"

    Science.gov (United States)

    Helsel, F.; Ivey, M.; Hardesty, J.; Roesler, E. L.; Dexheimer, D.

    2017-12-01

    Scientific Infrastructure To Support Atmospheric Science, Aerosol Science and UAS's for The Department Of Energy's Atmospheric Radiation Measurement Programs At The Mobile Facility 3 Located At Oliktok Point, Alaska.The Atmospheric Radiation Measurement (ARM) Program's Mobile Facility 3 (AMF3) located at Oliktok Point, Alaska is a U.S. Department of Energy (DOE) site designed to collect data and help determine the impact that clouds and aerosols have on solar radiation. AMF3 provides a scientific infrastructure to support instruments and collect arctic data for the international arctic research community. The infrastructure at AMF3/Oliktok is designed to be mobile and it may be relocated in the future to support other ARM science missions. AMF3's present base line instruments include: scanning precipitation Radars, cloud Radar, Raman Lidar, Eddy correlation flux systems, Ceilometer, Balloon sounding system, Atmospheric Emitted Radiance Interferometer (AERI), Micro-pulse Lidar (MPL) Along with all the standard metrological measurements. In addition AMF3 provides aerosol measurements with a Mobile Aerosol Observing System (MAOS). Ground support for Unmanned Aerial Systems (UAS) and tethered balloon flights. Data from these instruments and systems are placed in the ARM data archives and are available to the international research community. This poster will discuss what instruments and systems are at the ARM Research Facility at Oliktok Point Alaska.

  5. Do students eventually get to publish their research findings? The ...

    African Journals Online (AJOL)

    As a result, researchers are encouraged to share their research findings with the scientific world through peer review publications. In this study, we looked at the characteristics and publication rate of theses that documented studies on human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome in Cameroon ...

  6. Managing incidental findings in population based biobank research

    Directory of Open Access Journals (Sweden)

    Berge Solberg

    2012-04-01

    Full Text Available With the introduction of whole genome sequencing in medical research, the debate on how to handle incidental findings is becoming omnipresent. Much of the literature on the topic so far, seems to defend the researcher’s duty to inform, the participant’s right to know combined with a thorough informed consent in order to protect and secure high ethical standards in research. In this paper, we argue that this ethical response to incidental findings and whole genome sequencing is appropriate in a clinical context, in what we call therapeutic research. However, we further argue, that it is rather inappropriate in basic research, like the research going on in public health oriented population based biobanks. Our argument is based on two premises: First, in population based biobank research the duties and rights involved are radically different from a clinical based setting. Second, to introduce the ethical framework from the clinical setting into population based basic research, is not only wrong, but it may lead to unethical consequences. A Norwegian population based biobank and the research-ethical debate in Norway on the regulation of whole genome sequencing is used as an illustrative case to demonstrate the pitfalls when approaching the debate on incidental findings in population based biobank research.

  7. Recruiting Underserved Mothers to Medical Research: Findings from North Carolina

    Science.gov (United States)

    Spears, Chaya R.; Sandberg, Joanne C.; O’Neill, Jenna L.; Grzywacz, Joseph G.; Howard, Timothy D.; Feldman, Steven R.; Arcury, Thomas A.

    2014-01-01

    Representative samples are required for ethical, valid, and useful health research. Yet, recruiting participants, especially from historically underserved communities, can be challenging. This paper presents findings from in-depth interviews with 40 mothers about factors that might influence their willingness to participate or allow their children to participate in medical research. Saliency analysis organizes the findings. Frequent and important salient themes about research participation included concerns that it might cause participants harm, hope that participants might gain a health benefit, and recognition that time and transportation resources could limit participation. Ultimately, we propose that a theoretical model, such as the Theory of Planned Behavior (TPB), will facilitate more systematic evaluation of effective methods for recruitment and retention of participants in medical research. Future research should explore the utility of such a model for development of effective recruitment and retention strategies. PMID:24185171

  8. Incidental findings in youths volunteering for brain MRI research.

    Science.gov (United States)

    Gur, R E; Kaltman, D; Melhem, E R; Ruparel, K; Prabhakaran, K; Riley, M; Yodh, E; Hakonarson, H; Satterthwaite, T; Gur, R C

    2013-10-01

    MRIs are obtained in research in healthy and clinical populations, and incidental findings have been reported. Most studies have examined adults with variability in parameters of image acquisition and clinical measures available. We conducted a prospective study of youths and documented the frequency and concomitants of incidental findings. Youths (n = 1400) with an age range from 8-23 years were imaged on the same 3T scanner, with a standard acquisition protocol providing 1.0 mm(3) isotropic resolution of anatomic scans. All scans were reviewed by an experienced board-certified neuroradiologist and were categorized into 3 groups: 1) normal: no incidental findings; 2) coincidental: incidental finding(s) were noted, further reviewed with an experienced pediatric neuroradiologist, but were of no clinical significance; 3) incidental findings that on further review were considered to have potential clinical significance and participants were referred for appropriate clinical follow-up. Overall, 148 incidental findings (10.6% of sample) were noted, and of these, 12 required clinical follow-up. Incidental findings were not related to age. However, whites had a higher incidence of pineal cysts, and males had a higher incidence of cavum septum pellucidum, which was associated with psychosis-related symptoms. Incidental findings, moderated by race and sex, occur in approximately one-tenth of participants volunteering for pediatric research, with few requiring follow-up. The incidence supports a 2-tiered approach of neuroradiologic reading and clinical input to determine the potential significance of incidental findings detected on research MR imaging scans.

  9. Researchers Find Essential Brain Circuit in Visual Development

    Science.gov (United States)

    ... 2013 Researchers find essential brain circuit in visual development NIH-funded study could lead to new treatments for amblyopia. The cartoon at left shows the connections from the eyes to the brain in a mouse. The right image shows the binocular zone of the mouse ...

  10. Nest predation research: Recent findings and future perspectives

    Science.gov (United States)

    Chalfoun, Anna D.; Ibanez-Alamo, J. D.; Magrath, R. D.; Schmidt, Kenneth A.; Thomson, R. L.; Oteyza, Juan C.; Haff, T. M.; Martin, T.E.

    2016-01-01

    Nest predation is a key source of selection for birds that has attracted increasing attention from ornithologists. The inclusion of new concepts applicable to nest predation that stem from social information, eavesdropping or physiology has expanded our knowledge considerably. Recent methodological advancements now allow focus on all three players within nest predation interactions: adults, offspring and predators. Indeed, the study of nest predation now forms a vital part of avian research in several fields, including animal behaviour, population ecology, evolution and conservation biology. However, within nest predation research there are important aspects that require further development, such as the comparison between ecological and evolutionary antipredator responses, and the role of anthropogenic change. We hope this review of recent findings and the presentation of new research avenues will encourage researchers to study this important and interesting selective pressure, and ultimately will help us to better understand the biology of birds.

  11. The Ultrasonographic Findings of Trigger Points of Myofascial Pain Syndrome in a Rabbit Model

    International Nuclear Information System (INIS)

    Moon, Kyung Mi; Park, Seog Hee; Lee, Sang Heon; Kim, Joo Hyun; Kim, Han Kyum

    2005-01-01

    Myofascial pain syndrome (MPS) is a common cause of musculoskeletal pain. Myofascial trigger points (MTrPs) have been repeatedly described by numerous authors. However, there have been few studies in which their existence and behavior was supported and their location confirmed. The purpose of this study was to determine whether diagnostic ultrasonography is an objective diagnostic tool which is able to significantly identify or detect the soft tissue changes in the region of clinically identified active MTrPs by using a rabbit experimental model. Ten MPS model rabbits were used in this study. We made an MPS animal model by causing the rabbits to overuse one leg for 3 weeks by cutting the contralateral L4 spinal nerve root. We compared the ultrasonographic findings of the taut band at pre-OP with those at post-OP during the consecutive three week period. To find the taut bands of the muscle, after skin exposure, the muscles were gently rubbed or pinched with the thumb and index finger on the two opposing surfaces of the muscle across the direction of the fibers. Then, the muscle was held in the same way, but with a 5-8 MHz stick probe being used in place of the thumb. After the palpation of various muscles, we selected the hardest and largest myofascial trigger nodule, in order to observe the ultrasonographic and power Doppler findings of the MPS. The size, shape, echogenecity and vascularity of the MTrPs were observed. The analysis of the results of the ultrasonography revealed that all MTrPs have a hyperechoic area. The mean thickness of the hyperechoic lesion in the biceps was 0.96±0.14 cm in the MPS site (at pre-OP?), and 0.49±0.12 cm at post-OP 3weeks (p < 0.01). The hyperechoic lesions in all of the studied biceps femoris of the rabbits were observed by high resolution ultrasonography. No definitively decreased vascularity was observed within the hyperechoic area by power Doppler imaging. Until now, there has been no objective method for the diagnosis of MPS

  12. POLITENESS IN REQUESTS: SOME RESEARCH FINDINGS RELEVANT FOR INTERCULTURAL ENCOUNTERS

    Directory of Open Access Journals (Sweden)

    Aura CODREANU; Alina DEBU

    2011-01-01

    Full Text Available The major aim of this article is to analyze the relationship between indirectness and politeness in requests. The research project supporting the findings of the paper was undertaken in order to find out to what extent politeness and indirectness are viewed as overlapping or mutually excluding categories by Romanians compared to other nationalities, such as the British and the Hebrew. Another inherent goal of the paper is to provide an example of the socio linguistics instruments that can be employed in the investigation of the differences and similarities likely to emerge in intercultural encounters. Thus, we believe that only through similar research undertaken in the fields contributing to the emerging field of interculturality one can actually trespass the theoretical assumptions and move on to the identification of the right tools and means through which intercultural discourse to be approached at a pragmatic level and thus better understood and taught in educational establishments.

  13. Research findings can change attitudes about corporal punishment.

    Science.gov (United States)

    Holden, George W; Brown, Alan S; Baldwin, Austin S; Croft Caderao, Kathryn

    2014-05-01

    Positive attitudes toward the use of corporal punishment (CP) predict subsequent spanking behavior. Given that CP has frequently been associated with behavior problems in children and child maltreatment, this prevention work was designed to test whether adults' attitudes could be changed by informing participants about the research findings on problematic behaviors associated with CP. Two random assignment studies are reported. In Study 1, we tested whether an active reading condition would result in more attitude change than a passive condition. With a sample of 118 non-parent adults, we found that after reading very brief research summaries on the problems associated with CP, there was a significant decrease in favorable attitudes toward CP. Contrary to expectations, the magnitude of the change was comparable for active and passive processing conditions. In Study 2, we extended our approach to a sample of 520 parents and included a control group. A significant decrease in positive attitudes toward spanking was observed in the intervention group, but no change for the control group. Parents who were unaware of the research showed more change after reading the summaries. Thus, these studies demonstrate that a brief and cost-effective approach to raise awareness of research findings can reduce positive attitudes toward CP. Implications for prevention and intervention are discussed. Copyright © 2013. Published by Elsevier Ltd.

  14. Ethical responsibilities in nursing: research findings and issues.

    Science.gov (United States)

    Cassidy, V R

    1991-01-01

    Discussions in the literature assert that nurses are becoming increasingly cognizant of their ethical responsibilities, but that they are often ill prepared to participate in ethical decision making. A review of selected research literature from 1970 to 1987 was undertaken to validate these assertions. A total of 12 studies related to ethical responsibilities was identified in the review; all studies were published between 1980 and 1987. The majority of studies were at the descriptive and exploratory levels and employed Kohlberg's cognitive theory of moral development as their conceptual framework. Significant findings related to educational level and ethical responsibilities were consistent across studies. Findings related to age and clinical experience were mixed; the effects of economic level, religion-religiosity, ethnicity, and other variables on ethical responsibilities were not significant. Issues raised in the light of the existing research include the use of Kohlberg's theory as a conceptual orientation in nursing groups and limited data on the reliability and validity of instruments used in measuring ethical constructs. Recommendations for future research on ethical responsibilities include the validation of Kohlberg's theory for nursing investigations, exploration of other frameworks for developing a multidimensional view of ethical responsibilities, and the use of qualitative research designs.

  15. Research on Nonlinear Feature of Electrical Resistance of Acupuncture Points

    Directory of Open Access Journals (Sweden)

    Jianzi Wei

    2012-01-01

    Full Text Available A highly sensitive volt-ampere characteristics detecting system was applied to measure the volt-ampere curves of nine acupuncture points, LU9, HT7, LI4, PC6, ST36, SP6, KI3, LR3, and SP3, and corresponding nonacupuncture points bilaterally from 42 healthy volunteers. Electric currents intensity was increased from 0 μA to 20 μA and then returned to 0 μA again. The results showed that the volt-ampere curves of acupuncture points had nonlinear property and magnetic hysteresis-like feature. On all acupuncture point spots, the volt-ampere areas of the increasing phase were significantly larger than that of the decreasing phase (P<0.01. The volt-ampere areas of ten acupuncture point spots were significantly smaller than those of the corresponding nonacupuncture point spots when intensity was increase (P<0.05~P<0.001. And when intensity was decrease, eleven acupuncture point spots showed the same property as above (P<0.05~P<0.001, while two acupuncture point spots showed opposite phenomenon in which the areas of two acupuncture point spots were larger than those of the corresponding nonacupuncture point spots (P<0.05~P<0.01. These results show that the phenomenon of low skin resistance does not exist to all acupuncture points.

  16. Transforming the findings of narrative research into poetry.

    Science.gov (United States)

    Edwards, Sharon Lorraine

    2015-05-01

    To offer dramatic poetry as representing findings from narrative research that is more accessible. This article is drawn from the author's doctorate work on how students' stories about their 'clinical' experiences can aid learning. Nursing students' stories of clinical practice experiences when engaged in the care of patients represented as dramatic poetry. Qualitative analytical approaches in narrative data analysis to provide a review of student stories from a variety of perspectives. This article illustrates a method for converting story data to poetry. It suggests that a range of audiences can learn from nursing students' stories of clinical practice when translated into dramatic poetry. Audiences can come close to understanding what students are experiencing in practice when engaged in the care of patients and learning from their practice experiences, when these experiences are expressed as dramatic poetry. Representing findings from narrative research as dramatic poetry can help audiences engage with nursing students' experiences at an emotional level. Enabling researchers and readers to become immersed in the poem transforming their understanding of what the students have learned.

  17. Validation of intermediate end points in cancer research.

    Science.gov (United States)

    Schatzkin, A; Freedman, L S; Schiffman, M H; Dawsey, S M

    1990-11-21

    Investigations using intermediate end points as cancer surrogates are quicker, smaller, and less expensive than studies that use malignancy as the end point. We present a strategy for determining whether a given biomarker is a valid intermediate end point between an exposure and incidence of cancer. Candidate intermediate end points may be selected from case series, ecologic studies, and animal experiments. Prospective cohort and sometimes case-control studies may be used to quantify the intermediate end point-cancer association. The most appropriate measure of this association is the attributable proportion. The intermediate end point is a valid cancer surrogate if the attributable proportion is close to 1.0, but not if it is close to 0. Usually, the attributable proportion is close to neither 1.0 nor 0; in this case, valid surrogacy requires that the intermediate end point mediate an established exposure-cancer relation. This would in turn imply that the exposure effect would vanish if adjusted for the intermediate end point. We discuss the relative advantages of intervention and observational studies for the validation of intermediate end points. This validation strategy also may be applied to intermediate end points for adverse reproductive outcomes and chronic diseases other than cancer.

  18. Japanese attitudes toward the elderly: A review of research findings.

    Science.gov (United States)

    Koyano, W

    1989-10-01

    Reviewed are research findings related to Japanese attitudes toward the elderly. Although several studies approaching this theme have been published in Japan since 1952, most of them are not known outside Japan because they were written in Japanese. These studies explored the presence of negative attitudes which were usually masked with rituals of respect for the elderly. People's proper use of tatemae, culturally defined normative meaning, and honne, actual feeling, in their attitudes toward the elderly is discussed as a potential source of the American idealization of aging in Japan.

  19. Educating to Tolerance: Effects of Communicating Social Psychology Research Findings

    Directory of Open Access Journals (Sweden)

    Francesco La Barbera

    2015-08-01

    Full Text Available The effect of communicating social psychology research findings on ingroup bias in a classroom setting has been investigated. Two hundred and twenty one high school students either read or did not read a brief report about three classical social psychological studies, then completed evaluation scales for the ingroup and the outgroup. Participants’ motivation was manipulated, and the messages were different as regards the congruency between the content and participants’ actual intergroup experience. Results showed that communication exerted a significant effect in reducing ingroup bias for participants in the high motivation/high congruency condition, that is, the communication effect was moderated by the individual’s level of motivation and the content of the arguments proposed in the report. Practical implications of results for education work and stereotype change, limitations of the study, as well as possible directions for future research are discussed.

  20. Finding Non-Zero Stable Fixed Points of the Weighted Kuramoto model is NP-hard

    OpenAIRE

    Taylor, Richard

    2015-01-01

    The Kuramoto model when considered over the full space of phase angles [$0,2\\pi$) can have multiple stable fixed points which form basins of attraction in the solution space. In this paper we illustrate the fundamentally complex relationship between the network topology and the solution space by showing that determining the possibility of multiple stable fixed points from the network topology is NP-hard for the weighted Kuramoto Model. In the case of the unweighted model this problem is shown...

  1. Significant events in psychotherapy: An update of research findings.

    Science.gov (United States)

    Timulak, Ladislav

    2010-11-01

    Significant events research represents a specific approach to studying client-identified important moments in the therapy process. The current study provides an overview of the significant events research conducted, the methodology used together with findings and implications. PsychInfo database was searched with keywords such as significant events, important events, significant moments, important moments, and counselling or psychotherapy. The references of the selected studies were also searched. This process led to the identification of 41 primary studies that used client-identified significant event(s) as a main or secondary focus of the study. These were consequently reviewed with regard to their methodology and findings. The findings are presented according to type of study conducted. The impacts of helpful events reported by clients are focused on contributions to therapeutic relationship and to in-session outcomes. Hindering events focus on some client disappointment with the therapist or therapy. The group therapy modality highlighted additional helpful impacts (like learning from others). Perspectives on what is significant in therapy differ between clients and therapists. The intensive qualitative studies reviewed confirm that the processes involved in significant events are complex and ambiguous. Studies show that the helpful events may also contain many hindering elements and that specific events are deeply contextually embedded in the preceding events of therapy. Some studies suggest that helpful significant events are therapeutically productive although this may need to be established further. Specific intensive studies show that the clients' perceptions in therapy may differ dramatically from that of the therapist. Furthermore, the relational and emotional aspects of significant moments may be more important for the clients than the cognitive aspects of therapy which are frequently stressed by therapists. 2010 The British Psychological Society.

  2. Incidental Findings in Imaging Research: Evaluating Incidence, Benefit and Burden

    Science.gov (United States)

    Orme, Nicholas M.; Fletcher, Joel G.; Siddiki, Hassan A.; Harmsen, W. Scott; O’Byrne, Megan M.; Port, John D.; Tremaine, William J.; Pitot, Henry C.; McFarland, Beth; Robinson, Marguerite E.; Koenig, Barabara A.; King, Bernard F.; Wolf, Susan M.

    2013-01-01

    Context Little information exists concerning the frequency of clinically significant incidental findings (IFs) identified in the course of imaging research across a broad spectrum of imaging modalities and body regions. Objective To estimate the frequency with which research imaging IFs generate further clinical action, and the medical benefit/burden of identifying these IFs. Design, Setting, and Participants Retrospective review of subjects undergoing a research imaging exam that was interpreted by a radiologist for IFs in the first quarter of 2004, with 3-year clinical follow-up. An expert panel reviewed IFs generating clinical action to determine medical benefit/burden based on predefined criteria. Main Outcome Measures Frequency of (1) IFs that generated further clinical action by modality, body part, age, gender, and (2) IFs resulting in clear medical benefit or burden. Results 1376 patients underwent 1426 research imaging studies. 40% (567/1426) of exams had at least one IF (1055 total). Risk of an IF increased significantly by age (OR=1.5; [1.4–1.7=95% C.I.] per decade increase). Abdominopelvic CT generated more IFs than other exams (OR=18.9 compared with ultrasound; 9.2% with subsequent clinical action), with CT Thorax and MR brain next (OR=11.9 and 5.9; 2.8% and 2.2% with action, respectively). Overall 6.2% of exams (35/567) with an IF generated clinical action, resulting in clear medical benefit in 1.1% (6/567) and clear medical burden in 0.5% (3/567). In most instances, medical benefit/burden was unclear (4.6%; 26/567). Conclusions The frequency of IFs in imaging research exams varies significantly by imaging modality, body region and age. Research imaging studies at high risk for generating IFs can be identified. Routine evaluation of research images by radiologists may result in identification of IFs in a substantial number of cases and subsequent clinical action to address them in much smaller number. Such clinical action can result in medical

  3. Pairwise contact energy statistical potentials can help to find probability of point mutations.

    Science.gov (United States)

    Saravanan, K M; Suvaithenamudhan, S; Parthasarathy, S; Selvaraj, S

    2017-01-01

    To adopt a particular fold, a protein requires several interactions between its amino acid residues. The energetic contribution of these residue-residue interactions can be approximated by extracting statistical potentials from known high resolution structures. Several methods based on statistical potentials extracted from unrelated proteins are found to make a better prediction of probability of point mutations. We postulate that the statistical potentials extracted from known structures of similar folds with varying sequence identity can be a powerful tool to examine probability of point mutation. By keeping this in mind, we have derived pairwise residue and atomic contact energy potentials for the different functional families that adopt the (α/β) 8 TIM-Barrel fold. We carried out computational point mutations at various conserved residue positions in yeast Triose phosphate isomerase enzyme for which experimental results are already reported. We have also performed molecular dynamics simulations on a subset of point mutants to make a comparative study. The difference in pairwise residue and atomic contact energy of wildtype and various point mutations reveals probability of mutations at a particular position. Interestingly, we found that our computational prediction agrees with the experimental studies of Silverman et al. (Proc Natl Acad Sci 2001;98:3092-3097) and perform better prediction than i Mutant and Cologne University Protein Stability Analysis Tool. The present work thus suggests deriving pairwise contact energy potentials and molecular dynamics simulations of functionally important folds could help us to predict probability of point mutations which may ultimately reduce the time and cost of mutation experiments. Proteins 2016; 85:54-64. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  4. Rater cognition: review and integration of research findings.

    Science.gov (United States)

    Gauthier, Geneviève; St-Onge, Christina; Tavares, Walter

    2016-05-01

    . This framework could help bridge the gap between researchers adopting different perspectives when studying rater cognition and enable the interpretation of contradictory findings of raters' performance by determining which mechanism is enabled or disabled in any given context. © 2016 John Wiley & Sons Ltd.

  5. On Finding the Shortest Distance of a Point From a Line: Which ...

    Indian Academy of Sciences (India)

    One more application is in disaster management in the vicinity of high ... A proper safety dis- .... of a point in the n-dimensional Euclidean space Rn from a hyper- plane. Let the ... Let the coordinates in the new system be represented by. (x ,y ).

  6. LITERATURE REVIEWING WITH RESEARCH TOOLS, Part 2: Finding proper articles

    OpenAIRE

    Ebrahim, Nader Ale

    2017-01-01

    Research Tools” enable researchers to collect, organize, analyze, visualize and publicized research outputs. Dr. Nader has collected over 700 tools that enable students to follow the correct path in research and to ultimately produce high-quality research outputs with more accuracy and efficiency. It is assembled as an interactive Web-based mind map, titled “Research Tools”, which is updated periodically. “Research Tools” consists of a hierarchical set of nodes. It has four main nodes: (1)...

  7. Progress and results in Zero-Point Energy research

    International Nuclear Information System (INIS)

    King, M.B.

    1992-01-01

    This paper reports that the vacuum polarization of atomic nuclei may trigger a coherence in the zero-point energy (ZPE) whenever a large number of nuclei undergo abrupt, synchronous motion. Experimental evidence arises from the energy anomalies observed in heavy-ion collisions, ion-acoustic plasma oscillations, sonoluminescence, fractoemission, large charge density plasmoids, abrupt electric discharges, and light water cold fusion experiments. Further evidence arises from inventions that utilize coherent ion-acoustic activity to output anomalously excessive power

  8. Beyond the Page: A Process Review of Using Ethnodrama to Disseminate Research Findings.

    Science.gov (United States)

    Taylor, Jamilah; Namey, Emily; Carrington Johnson, Annette; Guest, Greg

    2017-06-01

    Public health researchers are charged with communicating study findings to appropriate audiences. Dissemination activities typically target the academic research community. However, as participatory research grows, researchers are increasingly exploring innovative dissemination techniques to reach broader audiences, particularly research participants and their communities. One technique is ethnodrama/ethnotheatre, a written or live performance based on study findings. Though used effectively in social change programs, dramas are seldom used to distribute research findings exclusively. Therefore, little information is available about planning and implementing an ethnodrama for this purpose. We present a case study describing the process of planning and implementing an ethnodrama in the context of the Durham Focus Group Study, which explored men's health-seeking behaviors and experiences with health and healthcare services in Durham, North Carolina. Here, we highlight lessons learned throughout the production of the ethnodrama, and how we addressed challenges associated with transforming research data into educational entertainment. Additionally, we provide discussion of audience feedback, which indicated that our ethnodrama evoked an urgency to change health behaviors among lay persons (67%) and delivery of health services among those identifying as providers (84%), pointing to the success of the performance in both entertaining and educating the audience.

  9. Uptake of Community-Based Peer Administered HIV Point-of-Care Testing: Findings from the PROUD Study.

    Directory of Open Access Journals (Sweden)

    Lisa Lazarus

    Full Text Available HIV prevalence among people who inject drugs (PWID in Ottawa is estimated at about 10%. The successful integration of peers into outreach efforts and wider access to HIV point-of-care testing (POCT create opportunities to explore the role of peers in providing HIV testing. The PROUD study, in partnership with Ottawa Public Health (OPH, sought to develop a model for community-based peer-administered HIV POCT.PROUD draws on community-based participatory research methods to better understand the HIV risk environment of people who use drugs in Ottawa. From March-October 2013, 593 people who reported injecting drugs or smoking crack cocaine were enrolled through street-based recruitment. Trained peer or medical student researchers administered a quantitative survey and offered an HIV POCT (bioLytical INSTI test to participants who did not self-report as HIV positive.550 (92.7% of the 593 participants were offered a POCT, of which 458 (83.3% consented to testing. Of those participants, 74 (16.2% had never been tested for HIV. There was no difference in uptake between testing offered by a peer versus a non-peer interviewer (OR = 1.05; 95% CI = 0.67-1.66. Despite testing those at high risk for HIV, only one new reactive test was identified.The findings from PROUD demonstrate high uptake of community-based HIV POCT. Peers were able to successfully provide HIV POCT and reach participants who had not previously been tested for HIV. Community-based and peer testing models provide important insights on ways to scale-up HIV prevention and testing among people who use drugs.

  10. Points of emphasis and objectives of reactor safety research

    International Nuclear Information System (INIS)

    Krewer, K.H.

    1982-01-01

    Reactor safety research is part of the presently running second programme on energy research and energy-engineering with which the Federal Government is connecting a whole bundle of economic and ecological aims: medium- and long-term assurance of energy supply, provision and efficient utilization of energy at favourable economic total costs, improvement of the technological performance, consideration of the requirements of the environmental protection, of the careful treatment of the resources, as well as of the protection of the population and personnel from the risks of conversion and use of energy. (orig.) [de

  11. Safety culture in a Belgian nuclear research centre from a social science point of view

    International Nuclear Information System (INIS)

    Fucks, I.; Hardeman, F.

    2002-01-01

    This paper is the result of a reflection within the framework of a Ph.D. research at SCK-CEN (Belgian Nuclear Research Centre) in collaboration with the University of Liege. The starting point of the work was the 'safety culture' model presented in the IAEA report 75-INSAG-4. This model is applied to the working organization of the SCK-CEN, also considering the safety culture as an open concept given its multi dimensionality. The methodology is based on three methods: observations, focus groups and interviews. The fieldwork was limited to two main installations: a research reactor, and a dismantling site. The preliminary findings are based on the data resulting from 4 Focus Groups. The most prominent components of a safety culture and the multiplicity of safety cultures in a large organization such as SCK-CEN will be discussed. (author)

  12. Some Growth Points in African Child Development Research

    Science.gov (United States)

    Serpell, Robert; Marfo, Kofi

    2014-01-01

    We reflect on ways in which research presented in earlier chapters responds to challenges of generating an African child development field and identify additional issues calling for the field's attention. The chapters collectively display a variety of African contexts and reflexive evidence of the authors' African cultural roots. Connecting…

  13. Securing medical research: a cybersecurity point of view.

    Science.gov (United States)

    Schneier, Bruce

    2012-06-22

    The problem of securing biological research data is a difficult and complicated one. Our ability to secure data on computers is not robust enough to ensure the security of existing data sets. Lessons from cryptography illustrate that neither secrecy measures, such as deleting technical details, nor national solutions, such as export controls, will work.

  14. Research review on flash point and explosion point for flammable liquids

    OpenAIRE

    POROWSKI RAFAŁ; RUDY WOJCIECH

    2011-01-01

    Основной причиной, из-за которой горючую жидкость обозначают параметром flash point, т.е. её температуру воспламенения, является оценка угрозы взрыва во время ее использования. Этот параметр определяется как минимальная температура жидкости, при которой образуется взрывоопасная атмосфера паров жидкости с воздухом, на поверхности жидкости или внутри устройства, в зависимости от исследовательского метода. С другой стороны, PN-EN 15794 вводит очередной параметр для легковоспламеняющихся жидкосте...

  15. [Evaluation and prioritisation of the scientific research in Spain. Researchers' point of view].

    Science.gov (United States)

    María Martín-Moreno, José; Juan Toharia, José; Gutiérrez Fuentes, José Antonio

    2008-12-01

    The assessment and prioritisation of research activity are essential components of any Science, Technology and Industry System. Data on researchers' perspectives in this respect are scarce. The objective of this paper was to describe Spanish scientists' point of view on the current evaluation system in Spain and how they believe this system should be functionally structured. From the sampling frame formed by established Spanish scientists, listed in the databases of CSIC and FIS (Institute of Health Carlos III), clinical, biomedical-non clinical, and physics and chemical researchers were randomly selected. Two hundred and eleven interviews were carried out by means of a computer-assisted telephone interviewing system. Researchers expressed their acknowledgement of progress in the Spanish research field but made their wish clear to progress towards better scientific scenarios. In their assessment, they gave a score of 5.4 to scientific policy, as opposed to 9.4 when speaking about the goals, reflecting the desire for a better policy definition, with clear objectives, stable strategies and better coordination of R&D activities (the current coordination received a score of 3.9, while the desirable coordination was valued as high as 9.2). There was certain agreement regarding the need for a prioritisation criteria which preserves some degree of creativity by researchers. They also stated that they would like to see an independent research structure with social prestige and influence. The interviewed researchers believe that the evaluation of scientific activities is fundamental in formulating a sound scientific policy. Prioritisation should arise from appropriate evaluation. Strategies properly coordinated among all the stakeholders (including the private sector) should be fostered. Budget sufficiency, stability, and better organization of independent researchers should be the backbone of any strategy tailored to increase their capacity to influence future scientific

  16. English-Language Teachers' Engagement with Research: Findings from Bangladesh

    Science.gov (United States)

    Anwaruddin, Sardar M.; Pervin, Nasrin

    2015-01-01

    In this article, we report on a small-scale study in which we investigated English-language teachers' engagement with educational research. We conceptualized engagement with research as reading and systematically using research for professional development. Using questionnaires and in-depth interviews, we gathered empirical materials from 40…

  17. Joining forces to find answers — The International Research Chairs ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-10-08

    Oct 8, 2010 ... Mobile Nav Footer Links ... the environment, and information technology hopes the new research program that ... Alper observes that the Canada Research Chairs program's success in achieving this goal provides one ... Like the Canada Research Chairs program, the IRCI emphasizes training students to ...

  18. Research on Language Learning Strategies: Methods, Findings, and Instructional Issues.

    Science.gov (United States)

    Oxford, Rebecca; Crookall, David

    1989-01-01

    Surveys research on formal and informal second-language learning strategies, covering the effectiveness of research methods involving making lists, interviews and thinking aloud, note-taking, diaries, surveys, and training. Suggestions for future and improved research are presented. (131 references) (CB)

  19. Research findings from the use of probiotics in tilapia aquaculture: A review.

    Science.gov (United States)

    Hai, Ngo Van

    2015-08-01

    This study aims to present research findings from the use of probiotics in tilapia aquaculture. In omnivorous species of tilapia aquaculture, intestines and gonads, rearing water and sediments or even commercial products, can be sources for acquiring appropriate probiotics. Administration of probiotics varies from direct oral/water routine to feed additives, of which the latter is most commonly used. Probiotic applications can be either mono or multiple strains. Dosage and duration of time are significant factors in providing desired results. As probiotics have been proven to be either immune enhancers and/or growth promoters in aquatic animals, several modes of actions of probiotics in enhancement of immune responses, and an improvement of growth and survival rates of tilapia are presented, while the effects of others are not yet understood to the same degree as for other fish species. Some points extracted from the research findings are emphasised for further investigation and development. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Dabrowski's Theory of Positive Disintegration and Giftedness: Overexcitability Research Findings

    Science.gov (United States)

    Mendaglio, Sal; Tillier, William

    2006-01-01

    During the past 20 years, a significant body of literature has emerged focusing on the application of Dabrowski's theory of positive disintegration (TPD) to the study of gifted individuals. Although much of this literature is prescriptive, some research reports spanning this time period are available. A perusal of research on TPD's applicability…

  1. Finding the Fabulous Few: Why Your Program Needs Sophisticated Research.

    Science.gov (United States)

    Pfizenmaier, Emily

    1981-01-01

    Fund raising, it is argued, needs sophisticated prospect research. Professional prospect researchers play an important role in helping to identify prospective donors and also in helping to stimulate interest in gift giving. A sample of an individual work-up on a donor and a bibliography are provided. (MLW)

  2. CASE STUDY: Lebanon — Researchers find new ways to resolve ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-12-13

    Dec 13, 2010 ... Communication is the key to conflict resolution A research team in ... as a model for a new applied research unit at the American University of Beirut. ... The LUN, for example, created a forum for discussing problems and ...

  3. Researching in education findings visibility: How Cubans are doing?

    Directory of Open Access Journals (Sweden)

    Torres, Paúl A.

    2012-07-01

    Full Text Available The paper presents an analysis of Cuban educational research visibility by considering international ranking positioning of intellectual production in the field of education. A case study is conducted with outstanding Cuban educational researchers comparing their results with other prestigious professionals in the continent. Finally, new basic resources are proposed and explained for improving Bibliometric indicators by taking advantage of Google Scholar potentials in favoring international ranking positioning.

  4. Finding Qualitative Research Evidence for Health Technology Assessment.

    Science.gov (United States)

    DeJean, Deirdre; Giacomini, Mita; Simeonov, Dorina; Smith, Andrea

    2016-08-01

    Health technology assessment (HTA) agencies increasingly use reviews of qualitative research as evidence for evaluating social, experiential, and ethical aspects of health technologies. We systematically searched three bibliographic databases (MEDLINE, CINAHL, and Social Science Citation Index [SSCI]) using published search filters or "hedges" and our hybrid filter to identify qualitative research studies pertaining to chronic obstructive pulmonary disease and early breast cancer. The search filters were compared in terms of sensitivity, specificity, and precision. Our screening by title and abstract revealed that qualitative research constituted only slightly more than 1% of all published research on each health topic. The performance of the published search filters varied greatly across topics and databases. Compared with existing search filters, our hybrid filter demonstrated a consistently high sensitivity across databases and topics, and minimized the resource-intensive process of sifting through false positives. We identify opportunities for qualitative health researchers to improve the uptake of qualitative research into evidence-informed policy making. © The Author(s) 2016.

  5. Finding weak points automatically

    International Nuclear Information System (INIS)

    Archinger, P.; Wassenberg, M.

    1999-01-01

    Operators of nuclear power stations have to carry out material tests at selected components by regular intervalls. Therefore a full automaticated test, which achieves a clearly higher reproducibility, compared to part automaticated variations, would provide a solution. In addition the full automaticated test reduces the dose of radiation for the test person. (orig.) [de

  6. User research of a voting machine: Preliminary findings and experiences

    NARCIS (Netherlands)

    de Jong, Menno D.T.; van Hoof, Joris Jasper; Gosselt, Jordi Franciscus

    2007-01-01

    This paper describes a usability study of the Nedap voting machine in the Netherlands. On the day of the national elections, 566 voters participated in our study immediately after having cast their real vote. The research focused on the correspondence between voter intents and voting results,

  7. Improving the production of applied health research findings: insights from a qualitative study of operational research.

    Science.gov (United States)

    Crowe, Sonya; Turner, Simon; Utley, Martin; Fulop, Naomi J

    2017-09-08

    Knowledge produced through applied health research is often of a form not readily accessible to or actionable by policymakers and practitioners, which hinders its implementation. Our aim was to identify research activities that can support the production of knowledge tailored to inform policy and practice. To do this, we studied an operational research approach to improving the production of applied health research findings. A 2-year qualitative study was conducted of the operational research contribution to a multidisciplinary applied health research project that was successful in rapidly informing national policy. Semi-structured interviews (n = 20) were conducted with all members of the project's research team and advisory group (patient and health professional representatives and academics). These were augmented by participant (> 150 h) and non-participant (> 15 h) observations focusing on the process and experience of attempting to support knowledge production. Data were analysed thematically using QSR NVivo software. Operational research performed a knowledge mediation role shaped by a problem-focused approach and an intent to perform those tasks necessary to producing readily implementable knowledge but outwith the remit of other disciplinary strands of the project. Three characteristics of the role were found to support this: engaging and incorporating different perspectives to improve services by capturing a range of health professional and patient views alongside quantitative and qualitative research evidence; rendering data meaningful by creating and presenting evidence in forms that are accessible to and engage different audiences, enabling them to make sense of it for practical use; and maintaining perceived objectivity and rigour by establishing credibility, perceived neutrality and confidence in the robustness of the research in order to unite diverse professionals in thinking creatively about system-wide service improvement. Our study

  8. Considering Actionability at the Participant's Research Setting Level for Anticipatable Incidental Findings from Clinical Research.

    Science.gov (United States)

    Ortiz-Osorno, Alberto Betto; Ehler, Linda A; Brooks, Judith

    2015-01-01

    Determining what constitutes an anticipatable incidental finding (IF) from clinical research and defining whether, and when, this IF should be returned to the participant have been topics of discussion in the field of human subject protections for the last 10 years. It has been debated that implementing a comprehensive IF-approach that addresses both the responsibility of researchers to return IFs and the expectation of participants to receive them can be logistically challenging. IFs have been debated at different levels, such as the ethical reasoning for considering their disclosure or the need for planning for them during the development of the research study. Some authors have discussed the methods for re-contacting participants for disclosing IFs, as well as the relevance of considering the clinical importance of the IFs. Similarly, other authors have debated about when IFs should be disclosed to participants. However, no author has addressed how the "actionability" of the IFs should be considered, evaluated, or characterized at the participant's research setting level. This paper defines the concept of "Actionability at the Participant's Research Setting Level" (APRSL) for anticipatable IFs from clinical research, discusses some related ethical concepts to justify the APRSL concept, proposes a strategy to incorporate APRSL into the planning and management of IFs, and suggests a strategy for integrating APRSL at each local research setting. © 2015 American Society of Law, Medicine & Ethics, Inc.

  9. Convenience samples and caregiving research: how generalizable are the findings?

    Science.gov (United States)

    Pruchno, Rachel A; Brill, Jonathan E; Shands, Yvonne; Gordon, Judith R; Genderson, Maureen Wilson; Rose, Miriam; Cartwright, Francine

    2008-12-01

    We contrast characteristics of respondents recruited using convenience strategies with those of respondents recruited by random digit dial (RDD) methods. We compare sample variances, means, and interrelationships among variables generated from the convenience and RDD samples. Women aged 50 to 64 who work full time and provide care to a community-dwelling older person were recruited using either RDD (N = 55) or convenience methods (N = 87). Telephone interviews were conducted using reliable, valid measures of demographics, characteristics of the care recipient, help provided to the care recipient, evaluations of caregiver-care recipient relationship, and outcomes common to caregiving research. Convenience and RDD samples had similar variances on 68.4% of the examined variables. We found significant mean differences for 63% of the variables examined. Bivariate correlations suggest that one would reach different conclusions using the convenience and RDD sample data sets. Researchers should use convenience samples cautiously, as they may have limited generalizability.

  10. Smoking cessation in women: findings from qualitative research.

    Science.gov (United States)

    Puskar, M

    1995-11-01

    The purpose of this descriptive exploratory study is to describe the experience of successful smoking cessation in adult women. The convenience sample included 10 women, ages 25 to 42, who had abstained from smoking for at least 6 months but not longer than 3 years. A semistructured interview format was used to elicit descriptions of the experience of successful smoking cessation from these subjects. The interview format explored the experience, including initial contemplation, the process of quitting, and maintenance of smoking abstinence. Interviews were audiotaped, transcribed, and then analyzed using methods outlined by Miles and Huberman [1]. Four themes emerged from the data: evolving commitment to health and personal growth, being stigmatized, changing conceptualization of smoking, and smoking cessation as a relational phenomenon. These findings were consistent with Pender's Health Promotion Model and have implications for nurse practitioners who counsel women on smoking cessation.

  11. Gate valve and motor-operator research findings

    International Nuclear Information System (INIS)

    Steele, R. Jr.; DeWall, K.G.; Watkins, J.C.; Russell, M.J.; Bramwell, D.

    1995-09-01

    This report provides an update on the valve research being sponsored by the US Nuclear Regulatory Commission (NRC) and conducted at the Idaho National Engineering Laboratory (INEL). The research addresses the need to provide assurance that motor-operated valves can perform their intended safety function, usually to open or close against specified (design basis) flow and pressure loads. This report describes several important developments: Two methods for estimating or bounding the design basis stem factor (in rising-stem valves), using data from tests less severe than design basis tests; a new correlation for evaluating the opening responses of gate valves and for predicting opening requirements; an extrapolation method that uses the results of a best effort flow test to estimate the design basis closing requirements of a gate valve that exhibits atypical responses (peak force occurs before flow isolation); and the extension of the original INEL closing correlation to include low- flow and low-pressure loads. The report also includes a general approach, presented in step-by-step format, for determining operating margins for rising-stem valves (gate valves and globe valves) as well as quarter-turn valves (ball valves and butterfly valves)

  12. EU socio-economic research on fusion: findings and program

    International Nuclear Information System (INIS)

    Tosato, G.C.

    2002-01-01

    In 1997 the European Commission launched a Socio-Economic Research program to study under which conditions future fusion power plants may become competitive, compatible with the energy supply system and acceptable for the public. The program is developed by independent experts making use of well established international methodologies. It has been shown, among others, that: 1) local communities are ready to support the construction of an experimental fusion facility, if appropriate communication and awareness campaigns are carried out; 2) since the externalities are much lower than for competitors, fusion power plants may become the major producer of base load electricity at the end of the century in Europe, if climate changes have to be mitigated, if the construction of new nuclear fission power plants continues to be constrained and if nuclear fusion power plants become commercially available in 2050. Cooperating with major international organizations, the program for next year aims to demonstrate that the potential global benefits of fusion power plants in the second half of the century largely outdo the RD and D costs borne in the first half to make it available. (author)

  13. EU socio-economic research on fusion: Findings and program

    International Nuclear Information System (INIS)

    Tosato, G.C.

    2003-01-01

    In 1997 the European Commission launched a Socio-Economic Research program to study under which conditions future fusion power plants may become competitive, compatible with the energy supply system and acceptable for the public. It has been shown, among others, that: 1) local communities are ready to support the construction of an experimental fusion facility, if appropriate communication and awareness campaigns are carried out; 2) since the externalities are much lower than for competitors, fusion power plants may become the major producer of base load electricity at the end of the century in Europe, if climate changes have to be mitigated, if the construction of new nuclear fission power plants continues to be constrained and if nuclear fusion power plants become commercially available in 2050. Cooperating with major international organizations, the program for next year aims to demonstrating, through technical economic programming models and global multi-regional energy environmental scenarios, that the potential global benefits of fusion power plants in the second half of the century largely outdo the RD and D costs borne in the first half to make it available. Making the public aware of such benefits through field experiences will be part of the program. (author)

  14. Exploiting multimedia in reproductive science education: research findings.

    Science.gov (United States)

    Senger, P L; Oki, A C; Trevisan, M S; McLean, D J

    2012-08-01

    Education in reproductive science is operating from an outdated paradigm of teaching and learning. Traditionally, reproductive education follows the pattern where students read a textbook, listen to instructor presentations, re-read the textbook and class notes and then complete a test. This paradigm is inefficient, costly and has not incorporated the potential that technology can offer with respect to increases in student learning. Further, teachers of reproductive science (and all of science for that matter) have little training in the use of documented methods of instructional design and cognitive psychology. Thus, most of us have learned to teach by repeating the approaches our mentors used (both good and bad). The technology now exists to explain complex topics using multimedia presentations in which digital animation and three-dimensional anatomical reconstructions greatly reduce time required for delivery while at the same time improving student understanding. With funding from the Small Business Innovation Research program through the U.S. Department of Education, we have developed and tested a multimedia approach to teaching complex concepts in reproductive physiology. The results of five separate experiments involving 1058 university students and 122 patients in an OB/GYN clinic indicate that students and patients learned as much or more in less time when viewing the multimedia presentations when compared to traditional teaching methodologies. © 2012 Blackwell Verlag GmbH.

  15. Researching the meaning of life: finding new sources of hope.

    Science.gov (United States)

    Alon, Shirly

    2010-01-01

    -disciplinary staff. Case illustrations for meaning--centered interventions will be discussed in the course of the paper. Cultural and traditional differences within the Israeli society, expressed in themes of work with patients, will lead to the conclusion, that there are many creative ways for researching meaning of life and sources for hope.

  16. Childhood leukaemia risks: from unexplained findings near nuclear installations to recommendations for future research

    International Nuclear Information System (INIS)

    Laurier, D; Jacob, S; Grosche, B; Dehos, A; Hornhardt, S; Ziegelberger, G

    2014-01-01

    Recent findings related to childhood leukaemia incidence near nuclear installations have raised questions which can be answered neither by current knowledge on radiation risk nor by other established risk factors. In 2012, a workshop was organised on this topic with two objectives: (a) review of results and discussion of methodological limitations of studies near nuclear installations; (b) identification of directions for future research into the causes and pathogenesis of childhood leukaemia. The workshop gathered 42 participants from different disciplines, extending widely outside of the radiation protection field. Regarding the proximity of nuclear installations, the need for continuous surveillance of childhood leukaemia incidence was highlighted, including a better characterisation of the local population. The creation of collaborative working groups was recommended for consistency in methodologies and the possibility of combining data for future analyses. Regarding the causes of childhood leukaemia, major fields of research were discussed (environmental risk factors, genetics, infections, immunity, stem cells, experimental research). The need for multidisciplinary collaboration in developing research activities was underlined, including the prevalence of potential predisposition markers and investigating further the infectious aetiology hypothesis. Animal studies and genetic/epigenetic approaches appear of great interest. Routes for future research were pointed out. (review)

  17. Entry Points When Undergraduate Research Mentors Reflect on Their Role: A Qualitative Case Study

    Science.gov (United States)

    Wallin, Patric; Adawi, Tom

    2018-01-01

    Graduate students and postdoctoral researchers are increasingly taking on mentoring roles in undergraduate research (UR). There is, however, a paucity of research focusing on how they conceptualize their mentoring role. In this qualitative interview study, we identified three entry points that mentors reflect on to define their role: (1) What are…

  18. Science in the Eyes of Preschool Children: Findings from an Innovative Research Tool

    Science.gov (United States)

    Dubosarsky, Mia D.

    How do young children view science? Do these views reflect cultural stereotypes? When do these views develop? These fundamental questions in the field of science education have rarely been studied with the population of preschool children. One main reason is the lack of an appropriate research instrument that addresses preschool children's developmental competencies. Extensive body of research has pointed at the significance of early childhood experiences in developing positive attitudes and interests toward learning in general and the learning of science in particular. Theoretical and empirical research suggests that stereotypical views of science may be replaced by authentic views following inquiry science experience. However, no preschool science intervention program could be designed without a reliable instrument that provides baseline information about preschool children's current views of science. The current study presents preschool children's views of science as gathered from a pioneering research tool. This tool, in the form of a computer "game," does not require reading, writing, or expressive language skills and is operated by the children. The program engages children in several simple tasks involving picture recognition and yes/no answers in order to reveal their views about science. The study was conducted with 120 preschool children in two phases and found that by the age of 4 years, participants possess an emergent concept of science. Gender and school differences were detected. Findings from this interdisciplinary study will contribute to the fields of early childhood, science education, learning technologies, program evaluation, and early childhood curriculum development.

  19. Obstacles of Scientific Research with Faculty of University of Jadara from Their Point of View

    Science.gov (United States)

    Hatamleh, Habes Moh'd

    2016-01-01

    This study aimed to estimate the existence of the scientific research obstacles' degree from the point of faculty at the University of Jadara from their point of view. The number of members that responded to the study reached 100 samples, and this number accounts for 80% of the study society. To achieve the objectives of the study, the researcher…

  20. Translating research findings into practice – the implementation of kangaroo mother care in Ghana

    Directory of Open Access Journals (Sweden)

    Bergh Anne-Marie

    2012-08-01

    Full Text Available Abstract Background Kangaroo mother care (KMC is a safe and effective method of caring for low birth weight infants and is promoted for its potential to improve newborn survival. Many countries find it difficult to take KMC to scale in healthcare facilities providing newborn care. KMC Ghana was an initiative to scale up KMC in four regions in Ghana. Research findings from two outreach trials in South Africa informed the design of the initiative. Two key points of departure were to equip healthcare facilities that conduct deliveries with the necessary skills for KMC practice and to single out KMC for special attention instead of embedding it in other newborn care initiatives. This paper describes the contextualisation and practical application of previous research findings and the results of monitoring the progress of the implementation of KMC in Ghana. Methods A three-phase outreach intervention was adapted from previous research findings to suit the local setting. A more structured system of KMC regional steering committees was introduced to drive the process and take the initiative forward. During Phase I, health workers in regions and districts were oriented in KMC and received basic support for the management of the outreach. Phase II entailed the strengthening of the regional steering committees. Phase III comprised a more formal assessment, utilising a previously validated KMC progress-monitoring instrument. Results Twenty-six out of 38 hospitals (68 % scored over 10 out of 30 and had reached the level of ‘evidence of practice’ by the end of Phase III. Seven hospitals exceeded expected performance by scoring at the level of ‘evidence of routine and institutionalised practice.’ The collective mean score for all participating hospitals was 12.07. Hospitals that had attained baby-friendly status or had been re-accredited in the five years before the intervention scored significantly better than the rest, with a mean score of 14

  1. Early Career Researchers Demand Full-text and Rely on Google to Find Scholarly Sources

    Directory of Open Access Journals (Sweden)

    Richard Hayman

    2017-12-01

    Full Text Available A Review of: Nicholas, D., Boukacem-Zeghmouri, C., Rodríguez-Bravo, B., Xu, J., Watkinson, A., Abrizah, A., Herman, E., & Świgoń, M. (2017. Where and how early career researchers find scholarly information. Learned Publishing, 30(1, 19-29. http://dx.doi.org/10.1002/leap.1087 Abstract Objective – To examine the attitudes and information behaviours of early career researchers (ECRs when locating scholarly information. Design – Qualitative longitudinal study. Setting – Research participants from the United Kingdom, United States of America, China, France, Malaysia, Poland, and Spain. Subjects – A total 116 participants from various disciplines, aged 35 and younger, who were holding or had previously held a research position, but not in a tenured position. All participants held a doctorate or were in the process of earning one. Methods – Using structured interviews of 60-90 minutes, researchers asked 60 questions of each participant via face-to-face, Skype, or telephone interviews. The interview format and questions were formed via focus groups. Main Results – As part of a longitudinal project, results reported are limited to the first year of the study, and focused on three primary questions identified by the authors: where do ECRs find scholarly information, whether they use their smartphones to locate and read scholarly information, and what social media do they use to find scholarly information. Researchers describe how ECRs themselves interpreted the phrase scholarly information to primarily mean journal articles, while the researchers themselves had a much expanded definition to include professional and “scholarly contacts, ideas, and data” (p. 22. This research shows that Google and Google Scholar are widely used by ECRs for locating scholarly information regardless of discipline, language, or geography. Their analysis by country points to currency and the combined breadth-and-depth search experience that Google provides as

  2. Text-in-context: a method for extracting findings in mixed-methods mixed research synthesis studies.

    Science.gov (United States)

    Sandelowski, Margarete; Leeman, Jennifer; Knafl, Kathleen; Crandell, Jamie L

    2013-06-01

    Our purpose in this paper is to propose a new method for extracting findings from research reports included in mixed-methods mixed research synthesis studies. International initiatives in the domains of systematic review and evidence synthesis have been focused on broadening the conceptualization of evidence, increased methodological inclusiveness and the production of evidence syntheses that will be accessible to and usable by a wider range of consumers. Initiatives in the general mixed-methods research field have been focused on developing truly integrative approaches to data analysis and interpretation. The data extraction challenges described here were encountered, and the method proposed for addressing these challenges was developed, in the first year of the ongoing (2011-2016) study: Mixed-Methods Synthesis of Research on Childhood Chronic Conditions and Family. To preserve the text-in-context of findings in research reports, we describe a method whereby findings are transformed into portable statements that anchor results to relevant information about sample, source of information, time, comparative reference point, magnitude and significance and study-specific conceptions of phenomena. The data extraction method featured here was developed specifically to accommodate mixed-methods mixed research synthesis studies conducted in nursing and other health sciences, but reviewers might find it useful in other kinds of research synthesis studies. This data extraction method itself constitutes a type of integration to preserve the methodological context of findings when statements are read individually and in comparison to each other. © 2012 Blackwell Publishing Ltd.

  3. The African Research Cloud - A Friendly Entry Point to Research Computing

    OpenAIRE

    Walt, Anelda Van der; Pretorius, Boeta

    2016-01-01

    The slides were presented at the first African Research Cloud Workshop in Pretoria, South Africa on 27 - 28 October 2016 [1].The slides formed part of an introduction for a session about using cloud infrastructure, and specifically the African Research Cloud, for training purposes.The session was co-facilitated with Dr Bradley Frank and Dr Michelle Cluver.[1] "African Research Cloud Workshop." The Institute for Data Intensive Astronomy (IDIA). IDIA, n.d. Web. 3 Nov. 2016.  

  4. Impact of point-of-sale tobacco display bans: findings from the International Tobacco Control Four Country Survey

    Science.gov (United States)

    Li, Lin; Borland, Ron; Fong, Geoffrey T.; Thrasher, James F.; Hammond, David; Cummings, Kenneth M.

    2013-01-01

    This study examined the impact of point-of-sale (POS) tobacco marketing restrictions in Australia and Canada, in relation to the United Kingdom and the United States where there were no such restrictions during the study period (2006–10). The data came from the International Tobacco Control Four Country Survey, a prospective multi-country cohort survey of adult smokers. In jurisdictions where POS display bans were implemented, smokers’ reported exposure to tobacco marketing declined markedly. From 2006 to 2010, in Canada, the percentages noticing POS tobacco displays declined from 74.1 to 6.1% [adjusted odds ratio (OR) = 0.26, P advertising decreased from 40.3 to 14.1% (adjusted OR = 0.61, P marketing in the United States and United Kingdom remained high during this period. In parallel, there were declines in reported exposures to other forms of advertising/promotion in Canada and Australia, but again, not in the United States or United Kingdom. Impulse purchasing of cigarettes was lower in places that enacted POS display bans. These findings indicate that implementing POS tobacco display bans does result in lower exposure to tobacco marketing and less frequent impulse purchasing of cigarettes. PMID:23640986

  5. Support for a ban on tobacco powerwalls and other point-of-sale displays: findings from focus groups.

    Science.gov (United States)

    Schmitt, Carol L; Allen, Jane A; Kosa, Katherine M; Curry, Laurel E

    2015-02-01

    This study uses focus group data to document consumer perceptions of powerwall and other point-of-sale (POS) tobacco displays, and support for a ban on tobacco displays. Four focus groups were conducted in 2012 by a trained moderator. The study comprised 34 adult residents of New York State, approximately half with children under age 18 years living at home. Measures used in the study were awareness and perceptions of powerwall and other POS displays, and level of support for a ban on tobacco displays. Analysis focused on perceptions of powerwall and other POS displays, level of support for a ban on tobacco displays and reasons participants oppose a display ban. This study documents a general lack of concern about tobacco use in the community, which does not appear to be associated with support for a ban on POS tobacco displays. Although all participants had seen tobacco powerwalls and most considered them to be a form of advertising, participants were divided as to whether they played a role in youth smoking. Additional research is warranted to determine what factors individuals weigh in assigning value to a ban on POS tobacco displays and other tobacco control policies and how educational efforts can influence those assessments. © The Author 2014. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  6. Malnutrition is independently associated with skin tears in hospital inpatient setting-Findings of a 6-year point prevalence audit.

    Science.gov (United States)

    Munro, Emma L; Hickling, Donna F; Williams, Damian M; Bell, Jack J

    2018-05-24

    Skin tears cause pain, increased length of stay, increased costs, and reduced quality of life. Minimal research reports the association between skin tears, and malnutrition using robust measures of nutritional status. This study aimed to articulate the association between malnutrition and skin tears in hospital inpatients using a yearly point prevalence of inpatients included in the Queensland Patient Safety Bedside Audit, malnutrition audits and skin tear audits conducted at a metropolitan tertiary hospital between 2010 and 2015. Patients were excluded if admitted to mental health wards or were <18 years. A total of 2197 inpatients were included, with a median age of 71 years. The overall prevalence of skin tears was 8.1%. Malnutrition prevalence was 33.5%. Univariate analysis demonstrated associations between age (P ˂ .001), body mass index (BMI) (P < .001) and malnutrition (P ˂ .001) but not gender (P = .319). Binomial logistic regression analysis modelling demonstrated that malnutrition diagnosed using the Subjective Global Assessment was independently associated with skin tear incidence (odds ratio, OR: 1.63; 95% confidence interval, CI: 1.13-2.36) and multiple skin tears (OR 2.48 [95% CI 1.37-4.50]). BMI was not independently associated with skin tears or multiple skin tears. This study demonstrated independent associations between malnutrition and skin tear prevalence and multiple skin tears. It also demonstrated the limitations of BMI as a nutritional assessment measure. © 2018 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

  7. Humor Scholarship and TESOL: Applying Findings and Establishing a Research Agenda

    Science.gov (United States)

    Bell, Nancy D.

    2011-01-01

    Research in the areas of second language (L2) pragmatics and of conversational humor has increased in recent decades, resulting in a strong base of knowledge from which applied linguists can draw information for teaching purposes and undertake future research. Yet, whereas empirical findings in L2 pragmatics are beginning to find their way into…

  8. Stakeholders in psychiatry and their attitudes toward receiving pertinent and incident findings in genomic research

    DEFF Research Database (Denmark)

    Sundby, Anna; Boolsen, Merete Watt; Burgdorf, Kristoffer Solvsten

    2017-01-01

    potential research participants and health professionals toward receiving pertinent and incidental findings. A cross-sectional online survey was developed to investigate the attitudes among research participants toward receiving genomic findings. A total of 2,637 stakeholders responded: 241 persons...... and information that is not of serious health importance. Psychiatrists and clinical geneticists were less positive about receiving genomic findings compared with blood donors. The attitudes toward receiving findings were very positive. Stakeholders were willing to refrain from receiving incidental information......Increasingly more psychiatric research studies use whole genome sequencing or whole exome sequencing. Consequently, researchers face difficult questions, such as which genomic findings to return to research participants and how. This study aims to gain more knowledge on the attitudes among...

  9. Power Trip Set-points of Reactor Protection System for New Research Reactor

    International Nuclear Information System (INIS)

    Lee, Byeonghee; Yang, Soohyung

    2013-01-01

    This paper deals with the trip set-point related to the reactor power considering the reactivity induced accident (RIA) of new research reactor. The possible scenarios of reactivity induced accidents were simulated and the effects of trip set-point on the critical heat flux ratio (CHFR) were calculated. The proper trip set-points which meet the acceptance criterion and guarantee sufficient margins from normal operation were then determined. The three different trip set-points related to the reactor power are determined based on the RIA of new research reactor during FP condition, over 0.1%FP and under 0.1%FP. Under various reactivity insertion rates, the CHFR are calculated and checked whether they meet the acceptance criterion. For RIA at FP condition, the acceptance criterion can be satisfied even if high power set-point is only used for reactor trip. Since the design of the reactor is still progressing and need a safety margin for possible design changes, 18 MW is recommended as a high power set-point. For RIA at 0.1%FP, high power setpoint of 18 MW and high log rate of 10%pp/s works well and acceptance criterion is satisfied. For under 0.1% FP operations, the application of high log rate is necessary for satisfying the acceptance criterion. Considering possible decrease of CHFR margin due to design changes, the high log rate is suggested to be 8%pp/s. Suggested trip set-points have been identified based on preliminary design data for new research reactor; therefore, these trip set-points will be re-established by considering design progress of the reactor. The reactor protection system (RPS) of new research reactor is designed for safe shutdown of the reactor and preventing the release of radioactive material to environment. The trip set point of RPS is essential for reactor safety, therefore should be determined to mitigate the consequences from accidents. At the same time, the trip set-point should secure margins from normal operational condition to avoid

  10. Social Science Research Related to Wildfire Management: An Overview of Recent Findings and Future Research Needs

    Science.gov (United States)

    Sarah M. McCaffrey; Eric Toman; Melanie Stidham; Bruce. Shindler

    2012-01-01

    As with other aspects of natural-resource management, the approach to managing wildland fires has evolved over time as scientific understanding has advanced and the broader context surrounding management decisions has changed. Prior to 2000 the primary focus of most fire research was on the physical and ecological aspects of fire; social science research was limited to...

  11. Researcher Tales and Research Ethics: The Spaces in Which We Find Ourselves

    Science.gov (United States)

    White, Julie; Fitzgerald, Tanya

    2010-01-01

    The tales we tell here focus on the ethical issues arising from our research practice with vulnerable young participants and those for whom research has been inextricably linked with European imperialism and colonialism. The importance of relational obligations, temporality and potential for a continuing narrative approach to ethical research…

  12. Capillary Discourses, Fissure Points, and Tacitly Confessing the Self: Foucault's Later Work and Educational Research

    Science.gov (United States)

    Worthman, Christopher; Troiano, Beverly

    2016-01-01

    This article draws on Foucault's later work to consider in an exploratory but specific way how that work can inform educational research. It introduces the concepts of "capillary discourses" and "fissure points" to show, by way of example, how a regime of truth such as neoliberalism shapes lifelong learning theory, the pedagogy…

  13. 76 FR 33763 - Findings of Misconduct in Science/Research Misconduct

    Science.gov (United States)

    2011-06-09

    ..., Ph.D., St. Jude Children's Research Hospital: Based on the findings of an investigation report by St... oversight review, ORI found that Philippe Bois, Ph.D., former postdoctoral fellow, Department of Biochemistry, St. Jude, engaged in misconduct in science and research misconduct in research funded by National...

  14. Sense of place in natural resource recreation and tourism: an evaluation and assessment of research findings.

    Science.gov (United States)

    Jennifer Farnum; Troy Hall; Linda E. Kruger

    2005-01-01

    Understanding sense of place and related concepts often presents challenges for both managers and researchers. Inconsistent application of terms, questions regarding their origin, and a lack of awareness of research findings contribute to the ambiguity of these concepts. This integrative review of research provides relevant, current information on the role of sense of...

  15. Information technology for clinical, translational and comparative effectiveness research. Findings from the section clinical research informatics.

    Science.gov (United States)

    Daniel, C; Choquet, R

    2013-01-01

    To summarize advances of excellent current research in the new emerging field of Clinical Research Informatics. Synopsis of four key articles selected for the IMIA Yearbook 2013. The selection was performed by querying PubMed and Web of Science with predefined keywords. From the original set of 590 papers, a first subset of 461 articles which was in the scope of Clinical Research Informatics was refined into a second subset of 79 relevant articles from which 15 articles were retained for peer-review. The four selected articles exemplify current research efforts conducted in the areas of data representation and management in clinical trials, secondary use of EHR data for clinical research, information technology platforms for translational and comparative effectiveness research and implementation of privacy control. The selected articles not only illustrate how innovative information technology supports classically organized randomized controlled trials but also demonstrate that the long promised benefits of electronic health care data for research are becoming a reality through concrete platforms and projects.

  16. Mechanism research on coupling effect between dew point corrosion and ash deposition

    International Nuclear Information System (INIS)

    Wang, Yun-Gang; Zhao, Qin-Xin; Zhang, Zhi-Xiang; Zhang, Zhi-Chao; Tao, Wen-Quan

    2013-01-01

    In order to study the coupling mechanism between ash deposition and dew point corrosion, five kinds of tube materials frequently used as anti-dew point corrosion materials were selected as research objects. Dew point corrosion and ash deposition experiments were performed with a new type experimental device in a Chinese thermal power plant. The microstructures of the materials and the composition of ash deposition were analyzed by X-ray diffraction (XRD) and Energy Dispersive Spectrometer (EDS). The results showed that the ash deposition layer could be divided into non-condensation zone, the main condensation zone and the secondary condensation zone. The acid vapor condensed in the main condensation zone rather than directly on the tube wall surface. The dew point corrosion mainly is oxygen corrosion under the condition of the viscosity ash deposition, and the corrosion products are composed of the ash and acid reaction products in the outer layer, iron sulfate in the middle layer, and iron oxide in the inner layer. The innermost layer is the main corrosion layer. With the increase of the tube wall temperature, the ash deposition changes from the viscosity ash deposition to the dry loose ash deposition, the ash deposition rate decreases dramatically and dew point corrosion is alleviated efficiently. The sulfuric dew point corrosion resistance of the five test materials is as follows: 316L > ND > Corten>20G > 20 steel. -- Highlights: ► Dew point corrosion and ash deposition tests of five materials were performed. ► Acid vapor condensed in the ash deposit rather than directly on the tube surface. ► Dew point corrosion resistance is as follow: 316L > ND > Corten>20G > 20 steel. ► Dew point corrosion mainly is oxygen corrosion under viscosity ash deposition

  17. Disseminating research findings: what should researchers do? A systematic scoping review of conceptual frameworks

    Science.gov (United States)

    2010-01-01

    Background Addressing deficiencies in the dissemination and transfer of research-based knowledge into routine clinical practice is high on the policy agenda both in the UK and internationally. However, there is lack of clarity between funding agencies as to what represents dissemination. Moreover, the expectations and guidance provided to researchers vary from one agency to another. Against this background, we performed a systematic scoping to identify and describe any conceptual/organising frameworks that could be used by researchers to guide their dissemination activity. Methods We searched twelve electronic databases (including MEDLINE, EMBASE, CINAHL, and PsycINFO), the reference lists of included studies and of individual funding agency websites to identify potential studies for inclusion. To be included, papers had to present an explicit framework or plan either designed for use by researchers or that could be used to guide dissemination activity. Papers which mentioned dissemination (but did not provide any detail) in the context of a wider knowledge translation framework, were excluded. References were screened independently by at least two reviewers; disagreements were resolved by discussion. For each included paper, the source, the date of publication, a description of the main elements of the framework, and whether there was any implicit/explicit reference to theory were extracted. A narrative synthesis was undertaken. Results Thirty-three frameworks met our inclusion criteria, 20 of which were designed to be used by researchers to guide their dissemination activities. Twenty-eight included frameworks were underpinned at least in part by one or more of three different theoretical approaches, namely persuasive communication, diffusion of innovations theory, and social marketing. Conclusions There are currently a number of theoretically-informed frameworks available to researchers that can be used to help guide their dissemination planning and activity

  18. Disseminating research findings: what should researchers do? A systematic scoping review of conceptual frameworks

    Directory of Open Access Journals (Sweden)

    Calnan Mike W

    2010-11-01

    Full Text Available Abstract Background Addressing deficiencies in the dissemination and transfer of research-based knowledge into routine clinical practice is high on the policy agenda both in the UK and internationally. However, there is lack of clarity between funding agencies as to what represents dissemination. Moreover, the expectations and guidance provided to researchers vary from one agency to another. Against this background, we performed a systematic scoping to identify and describe any conceptual/organising frameworks that could be used by researchers to guide their dissemination activity. Methods We searched twelve electronic databases (including MEDLINE, EMBASE, CINAHL, and PsycINFO, the reference lists of included studies and of individual funding agency websites to identify potential studies for inclusion. To be included, papers had to present an explicit framework or plan either designed for use by researchers or that could be used to guide dissemination activity. Papers which mentioned dissemination (but did not provide any detail in the context of a wider knowledge translation framework, were excluded. References were screened independently by at least two reviewers; disagreements were resolved by discussion. For each included paper, the source, the date of publication, a description of the main elements of the framework, and whether there was any implicit/explicit reference to theory were extracted. A narrative synthesis was undertaken. Results Thirty-three frameworks met our inclusion criteria, 20 of which were designed to be used by researchers to guide their dissemination activities. Twenty-eight included frameworks were underpinned at least in part by one or more of three different theoretical approaches, namely persuasive communication, diffusion of innovations theory, and social marketing. Conclusions There are currently a number of theoretically-informed frameworks available to researchers that can be used to help guide their

  19. Increasing Use of Research Findings in Improving Evidence-Based Health Policy at the National Level

    Directory of Open Access Journals (Sweden)

    Meiwita Budiharsana

    2017-11-01

    Full Text Available In February 2016, the Minister of Health decided to increase the use of research findings in improving the quality of the national health policy and planning. The Ministry of Health has instructed the National Institute of Health Research and Development or NIHRD to play a stronger role of monitoring and evaluating all health programs, because “their opinion and research findings should be the basis for changes in national health policies and planning”. Compared to the past, the Ministry of Health has increased the research budget for evidence-based research tremendously. However, there is a gap between the information needs of program and policy-makers and the information offered by researchers. A close dialogue is needed between the users (program managers, policy makers and planners and the suppliers (researchers and evaluators to ensure that the evidence-based supplied by research is useful for programs, planning and health policy.

  20. Registered nurses' use of research findings in the care of older people.

    Science.gov (United States)

    Boström, Anne-Marie; Kajermo, Kerstin Nilsson; Nordström, Gun; Wallin, Lars

    2009-05-01

    To describe registered nurses' reported use of research in the care of older people and to examine associations between research use and factors related to the elements: the communication channels, the adopter and the social system. Research use among registered nurses working in hospital settings has been reported in many studies. Few studies, however, have explored the use of research among registered nurses working in the care of older people. A cross-sectional survey. In eight municipalities, all registered nurses (n = 210) working in older people care were invited to participate (response rate 67%). The Research Utilisation Questionnaire was adopted. Questions concerning the work organisation and research-related resources were sent to the Community Chief Nurse at each municipality. Descriptive statistics and logistic regression were applied. The registered nurses reported a relatively low use of research findings in daily practice, despite reporting a positive attitude to research. The registered nurses reported lack of access to research reports at the work place and that they had little support from unit managers and colleagues. Registered nurses working in municipalities with access to research-related resources reported more use of research than registered nurses without resources. The factors 'Access to research findings at work place', 'Positive attitudes to research' and 'Nursing programme at university level' were significantly associated with research use. There is a great potential to increase registered nurses' use of research findings in the care of older people. Factors which were linked to the communication channels and the adopter were associated with research use. Strategies to enhance research use should focus on access to and adequate training in using information sources, increased knowledge on research methodology and nursing science and a supportive organisation.

  1. Ileocaecal Intussusception with a Lead Point: Unusual MDCT Findings of Active Crohn’s Disease Involving the Appendix

    Directory of Open Access Journals (Sweden)

    Ebru Ozan

    2015-01-01

    Full Text Available Adult intussusception is a rare entity accounting for 1% of all bowel obstructions. Unlike intussusceptions in children, which are idiopathic in 90% of cases, adult intussusceptions have an identifiable cause (lead point in the majority of cases. Crohn’s disease (CD may affect any part of the gastrointestinal tract, including the appendix. It was shown to be a predisposing factor for intussusception. Here, we report a rare case of adult intussusception with a lead point, emphasizing diagnostic input of multidetector computed tomography (MDCT in a patient with active CD that involves the appendix.

  2. Standardized End Point Definitions for Coronary Intervention Trials: The Academic Research Consortium-2 Consensus Document.

    Science.gov (United States)

    Garcia-Garcia, Hector M; McFadden, Eugène P; Farb, Andrew; Mehran, Roxana; Stone, Gregg W; Spertus, John; Onuma, Yoshinobu; Morel, Marie-Angèle; van Es, Gerrit-Anne; Zuckerman, Bram; Fearon, William F; Taggart, David; Kappetein, Arie-Pieter; Krucoff, Mitchell W; Vranckx, Pascal; Windecker, Stephan; Cutlip, Donald; Serruys, Patrick W

    2018-06-14

    The Academic Research Consortium (ARC)-2 initiative revisited the clinical and angiographic end point definitions in coronary device trials, proposed in 2007, to make them more suitable for use in clinical trials that include increasingly complex lesion and patient populations and incorporate novel devices such as bioresorbable vascular scaffolds. In addition, recommendations for the incorporation of patient-related outcomes in clinical trials are proposed. Academic Research Consortium-2 is a collaborative effort between academic research organizations in the United States and Europe, device manufacturers, and European, US, and Asian regulatory bodies. Several in-person meetings were held to discuss the changes that have occurred in the device landscape and in clinical trials and regulatory pathways in the last decade. The consensus-based end point definitions in this document are endorsed by the stakeholders of this document and strongly advocated for clinical trial purposes. This Academic Research Consortium-2 document provides further standardization of end point definitions for coronary device trials, incorporating advances in technology and knowledge. Their use will aid interpretation of trial outcomes and comparison among studies, thus facilitating the evaluation of the safety and effectiveness of these devices.

  3. Impact of problem finding on the quality of authentic open inquiry science research projects

    Science.gov (United States)

    Labanca, Frank

    2008-11-01

    Problem finding is a creative process whereby individuals develop original ideas for study. Secondary science students who successfully participate in authentic, novel, open inquiry studies must engage in problem finding to determine viable and suitable topics. This study examined problem finding strategies employed by students who successfully completed and presented the results of their open inquiry research at the 2007 Connecticut Science Fair and the 2007 International Science and Engineering Fair. A multicase qualitative study was framed through the lenses of creativity, inquiry strategies, and situated cognition learning theory. Data were triangulated by methods (interviews, document analysis, surveys) and sources (students, teachers, mentors, fair directors, documents). The data demonstrated that the quality of student projects was directly impacted by the quality of their problem finding. Effective problem finding was a result of students using resources from previous, specialized experiences. They had a positive self-concept and a temperament for both the creative and logical perspectives of science research. Successful problem finding was derived from an idiosyncratic, nonlinear, and flexible use and understanding of inquiry. Finally, problem finding was influenced and assisted by the community of practicing scientists, with whom the students had an exceptional ability to communicate effectively. As a result, there appears to be a juxtaposition of creative and logical/analytical thought for open inquiry that may not be present in other forms of inquiry. Instructional strategies are suggested for teachers of science research students to improve the quality of problem finding for their students and their subsequent research projects.

  4. An Attachment Perspective on the Child--Dog Bond: Interdisciplinary and International Research Findings

    Science.gov (United States)

    Jalongo, Mary Renck

    2015-01-01

    Understanding the process of attachment formation in young children has been a focal point in child development research for decades. However, young children's attachments are not only with human beings; they also form bonds with companion animals, particularly dogs ("Canis familiaris"). Given the number of dogs that are kept by families…

  5. The Ademe research programme on atmospheric emissions from composting. Research findings and literature review - final report

    International Nuclear Information System (INIS)

    Deportes, Isabelle; Mallard, Pascal; Loyon, Laurence; Guiziou, Fabrice; Fraboulet, Isaline; Clincke, Anne-Sophie; Fraboulet, Isaline; Tognet, Frederic; Bessagnet, Bertrand; Durif, Marc; Poulleau, Jean; Bacheley, Helene; Delabre, Karine; Zan-Alvarez, Patricia; Gourland, Pauline; Wery, Nathalie; Moletta-Denat, Marina; Deportes, Isabelle; Stavrakakis, Christophe; Schlosser, Olivier; Decottignies, Virginie; Akerman, Anna; Martel, Jean Luc; Senante, Elena; Givelet, Arnaud; Batton-Hubert, Mireille; Vaillant, Herve; Chovelon, Jean-Marc; Pradelle, Frederic; Sassi, Jean-Francois; Teigne, Delphine; Duchaine, Caroline; Jean, Thierry; Lavoie, Jacques; Le Cloarec, Pierre; Levasseur, Jean-Pierre; Morcet, Muriel; Rivet, Marie; Romain, Anne-Claude

    2012-07-01

    Emissions of gas and particulates (dusts, mineral and organic) linked to composting wastes essentially come from the biodegradation of organic matter by micro-organisms and from the related site management activities, especially material handling (of the raw waste, mixes and compost): movements, turning, sieving and loading. Carbon dioxide (CO 2 ) is, in terms of mass, the main gas produced (along with water vapor) during composting. However, many other gases emitted in small amounts can also have a major impact on the environment and/or health risks. Such is the case for nitrous oxide (N 2 O) and methane (CH 4 ) with respect to global warming, and also for ammonia (NH 3 ) with respect to acidification and eutrophication of the local environment, and of a wide range of sulfur-based and volatile organic compounds which can potentially lead to very unpleasant (or offensive) odors and health risks. In the case of emitted dust particles, these can often carry micro-organisms and/or biological compounds with the known health effects of inflammation, allergic reactions and infection. Thus dealing with these emissions and the evaluation of their health and environmental impacts represents key aspects in the long term sustainability of the composting option. Even if the understanding of these emissions remains incomplete, taking into account the wide range of solid wastes treated and of the methods of composting available, efforts have been made these last years to better characterize the substrate and to improve the related measurement methods. ADEME launched in 2006 a research programme specifically addressing this theme in particular, involving many research organizations, technical centres, research consultancies and industrial partners. The work carried out in this framework has enabled an improvement in the knowledge of characterizing emissions, of their sources and controlling factors, of their metrology (whether at the source or within the environment around

  6. Impact of point-of-sale tobacco display bans: findings from the International Tobacco Control Four Country Survey

    OpenAIRE

    Li, Lin; Borland, Ron; Fong, Geoffrey T.; Thrasher, James F.; Hammond, David; Cummings, Kenneth M.

    2013-01-01

    This study examined the impact of point-of-sale (POS) tobacco marketing restrictions in Australia and Canada, in relation to the United Kingdom and the United States where there were no such restrictions during the study period (2006–10). The data came from the International Tobacco Control Four Country Survey, a prospective multi-country cohort survey of adult smokers. In jurisdictions where POS display bans were implemented, smokers’ reported exposure to tobacco marketing declined markedly....

  7. Recruitment methods for survey research: Findings from the Mid-South Clinical Data Research Network.

    Science.gov (United States)

    Heerman, William J; Jackson, Natalie; Roumie, Christianne L; Harris, Paul A; Rosenbloom, S Trent; Pulley, Jill; Wilkins, Consuelo H; Williams, Neely A; Crenshaw, David; Leak, Cardella; Scherdin, Jon; Muñoz, Daniel; Bachmann, Justin; Rothman, Russell L; Kripalani, Sunil

    2017-11-01

    The objective of this study was to report survey response rates and demographic characteristics of eight recruitment approaches to determine acceptability and effectiveness of large-scale patient recruitment among various populations. We conducted a cross sectional analysis of survey data from two large cohorts. Patients were recruited from the Mid-South Clinical Data Research Network using clinic-based recruitment, research registries, and mail, phone, and email approaches. Response rates are reported as patients who consented for the survey divided by the number of eligible patients approached. We contacted more than 90,000 patients and 13,197 patients completed surveys. Median age was 56.3years (IQR 40.9, 67.4). Racial/ethnic distribution was 84.1% White, non-Hispanic; 9.9% Black, non-Hispanic; 1.8% Hispanic; and 4.0% other, non-Hispanic. Face-to-face recruitment had the highest response rate of 94.3%, followed by participants who "opted-in" to a registry (76%). The lowest response rate was for unsolicited emails from the clinic (6.1%). Face-to-face recruitment enrolled a higher percentage of participants who self-identified as Black, non-Hispanic compared to other approaches (18.6% face-to-face vs. 8.4% for email). Technology-enabled recruitment approaches such as registries and emails are effective for recruiting but may yield less racial/ethnic diversity compared to traditional, more time-intensive approaches. Copyright © 2017. Published by Elsevier Inc.

  8. Reconciling incongruous qualitative and quantitative findings in mixed methods research: exemplars from research with drug using populations.

    Science.gov (United States)

    Wagner, Karla D; Davidson, Peter J; Pollini, Robin A; Strathdee, Steffanie A; Washburn, Rachel; Palinkas, Lawrence A

    2012-01-01

    Mixed methods research is increasingly being promoted in the health sciences as a way to gain more comprehensive understandings of how social processes and individual behaviours shape human health. Mixed methods research most commonly combines qualitative and quantitative data collection and analysis strategies. Often, integrating findings from multiple methods is assumed to confirm or validate the findings from one method with the findings from another, seeking convergence or agreement between methods. Cases in which findings from different methods are congruous are generally thought of as ideal, whilst conflicting findings may, at first glance, appear problematic. However, the latter situation provides the opportunity for a process through which apparently discordant results are reconciled, potentially leading to new emergent understandings of complex social phenomena. This paper presents three case studies drawn from the authors' research on HIV risk amongst injection drug users in which mixed methods studies yielded apparently discrepant results. We use these case studies (involving injection drug users [IDUs] using a Needle/Syringe Exchange Program in Los Angeles, CA, USA; IDUs seeking to purchase needle/syringes at pharmacies in Tijuana, Mexico; and young street-based IDUs in San Francisco, CA, USA) to identify challenges associated with integrating findings from mixed methods projects, summarize lessons learned, and make recommendations for how to more successfully anticipate and manage the integration of findings. Despite the challenges inherent in reconciling apparently conflicting findings from qualitative and quantitative approaches, in keeping with others who have argued in favour of integrating mixed methods findings, we contend that such an undertaking has the potential to yield benefits that emerge only through the struggle to reconcile discrepant results and may provide a sum that is greater than the individual qualitative and quantitative parts

  9. Collection and accumulation of seismic safety research findings, and considerations for information dissemination

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-08-15

    Seismic Safety Division of JNES is collecting and analyzing the findings of seismic safety research, and is developing a system to organize and disseminate the information internally and internationally. These tasks have been conducted in response to the lessons learned from Fukushima Daiichi NPP accident. The overview of the tasks is as follows; 1) Collection of the knowledge and findings from seismic safety research. JNES collects information on seismic safety researches including the 2011 off the Pacific coast of Tohoku Earthquake. The information is analyzed whether it is important for regulation to increase seismic safety of NPP. 2) Constructing database of seismic safety research. JNES collects information based on documents published by committee and constructs database of active faults around NPP sites in order to incorporate in the seismic safety review. 3) Dissemination of information related to seismic safety. JNES disseminates outcomes of own researches internally and internationally. (author)

  10. Collection and accumulation of seismic safety research findings, and considerations for information dissemination

    International Nuclear Information System (INIS)

    2013-01-01

    Seismic Safety Division of JNES is collecting and analyzing the findings of seismic safety research, and is developing a system to organize and disseminate the information internally and internationally. These tasks have been conducted in response to the lessons learned from Fukushima Daiichi NPP accident. The overview of the tasks is as follows; 1) Collection of the knowledge and findings from seismic safety research. JNES collects information on seismic safety researches including the 2011 off the Pacific coast of Tohoku Earthquake. The information is analyzed whether it is important for regulation to increase seismic safety of NPP. 2) Constructing database of seismic safety research. JNES collects information based on documents published by committee and constructs database of active faults around NPP sites in order to incorporate in the seismic safety review. 3) Dissemination of information related to seismic safety. JNES disseminates outcomes of own researches internally and internationally. (author)

  11. Commenting on Findings in Qualitative and Quantitative Research Articles’ Discussion Sections in Applied Linguistics

    Directory of Open Access Journals (Sweden)

    Leila Dobakhti

    2013-09-01

    Full Text Available Research articles have received a wide interest in discourse studies particularly in genre analysis over the last few decades. A vast number of studies have focused on identifying the organizational patterns of research articles in various fields. However, to date, no study has been conducted on generic structure of qualitative and quantitative research articles. This study investigates the importance of commenting on findings in Discussion section of qualitative and quantitative research articles and the strategies that these two types of articles employ in making comments. The analysis shows that while commenting on findings is an important feature in both sets of articles, different strategies of commenting are favored in each type of articles. The differences can be attributed to the different epistemology of qualitative and quantitative research.

  12. RESEARCH OF REGISTRATION APPROACHES OF THERMAL INFRARED IMAGES AND INTENSITY IMAGES OF POINT CLOUD

    Directory of Open Access Journals (Sweden)

    L. Liu

    2017-09-01

    Full Text Available In order to realize the analysis of thermal energy of the objects in 3D vision, the registration approach of thermal infrared images and TLS (Terrestrial Laser Scanner point cloud was studied. The original data was pre-processed. For the sake of making the scale and brightness contrast of the two kinds of data meet the needs of basic matching, the intensity image of point cloud was produced and projected to spherical coordinate system, histogram equalization processing was done for thermal infrared image.This paper focused on the research of registration approaches of thermal infrared images and intensity images of point cloud based on SIFT,EOH-SIFT and PIIFD operators. The latter of which is usually used for medical image matching with different spectral character. The comparison results of the experiments showed that PIIFD operator got much more accurate feature point correspondences compared to SIFT and EOH-SIFT operators. The thermal infrared image and intensity image also have ideal overlap results by quadratic polynomial transformation. Therefore, PIIFD can be used as the basic operator for the registration of thermal infrared images and intensity images, and the operator can also be further improved by incorporating the iteration method.

  13. Novel approach to improve molecular imaging research: Correlation between macroscopic and molecular pathological findings in patients

    Energy Technology Data Exchange (ETDEWEB)

    Boehm, Ingrid, E-mail: i.boehm@uni-bonn.de [Department of Diagnostic Radiology, ZARF Project, Center for Molecular Imaging Research MBMB, Philipps University of Marburg, Baldingerstrasse, 35039 Marburg (Germany)

    2011-09-15

    Purpose: Currently, clinical research approaches are sparse in molecular imaging studies. Moreover, possible links between imaging features and pathological laboratory parameters are unknown, so far. Therefore, the goal was to find a possible relationship between imaging features and peripheral blood cell apoptosis, and thereby to present a novel way to complement molecular imaging research. Materials and methods: The investigation has been done in systemic lupus erythematosus (SLE), a prototype of an autoimmune disease characterized by multiorgan involvement, autoantibody production, and disturbed apoptosis. Retrospectively, radiological findings have been compared to both autoantibody findings and percentage apoptotic blood cells. Results: Two SLE groups could be identified: patients with normal (annexin V binding < 20%), and with increased apoptosis (annexin V binding > 20%) of peripheral blood cells. The frequency of radiological examinations in SLE patients significantly correlated with an increased percentage of apoptotic cells (p < 0.005). In patients with characteristic imaging findings (e.g. lymph node swelling, pleural effusion) an elevated percentage of apoptotic cells was present. In contrast SLE-patients with normal imaging findings or uncharacteristic results of minimal severity had normal percentages of apoptotic blood cells. Conclusion: This correlation between radiographic findings and percentage of apoptotic blood cells provides (1) further insight into pathological mechanisms of SLE, (2) will offer the possibility to introduce apoptotic biomarkers as molecular probes for clinical molecular imaging approaches in future to early diagnose organ complaints in patients with SLE, and (3) is a plea to complement molecular imaging research by this clinical approach.

  14. Early Career Researchers Demand Full-text and Rely on Google to Find Scholarly Sources

    OpenAIRE

    Richard Hayman

    2017-01-01

    A Review of: Nicholas, D., Boukacem-Zeghmouri, C., Rodríguez-Bravo, B., Xu, J., Watkinson, A., Abrizah, A., Herman, E., & Świgoń, M. (2017). Where and how early career researchers find scholarly information. Learned Publishing, 30(1), 19-29. http://dx.doi.org/10.1002/leap.1087 Abstract Objective – To examine the attitudes and information behaviours of early career researchers (ECRs) when locating scholarly information. Design – Qualitative longitudinal study. Setting – R...

  15. Clinical verification of genetic results returned to research participants: findings from a Colon Cancer Family Registry.

    Science.gov (United States)

    Laurino, Mercy Y; Truitt, Anjali R; Tenney, Lederle; Fisher, Douglass; Lindor, Noralane M; Veenstra, David; Jarvik, Gail P; Newcomb, Polly A; Fullerton, Stephanie M

    2017-11-01

    The extent to which participants act to clinically verify research results is largely unknown. This study examined whether participants who received Lynch syndrome (LS)-related findings pursued researchers' recommendation to clinically verify results with testing performed by a CLIA-certified laboratory. The Fred Hutchinson Cancer Research Center site of the multinational Colon Cancer Family Registry offered non-CLIA individual genetic research results to select registry participants (cases and their enrolled relatives) from 2011 to 2013. Participants who elected to receive results were counseled on the importance of verifying results at a CLIA-certified laboratory. Twenty-six (76.5%) of the 34 participants who received genetic results completed 2- and 12-month postdisclosure surveys; 42.3% of these (11/26) participated in a semistructured follow-up interview. Within 12 months of result disclosure, only 4 (15.4%) of 26 participants reported having verified their results in a CLIA-certified laboratory; of these four cases, all research and clinical results were concordant. Reasons for pursuing clinical verification included acting on the recommendation of the research team and informing future clinical care. Those who did not verify results cited lack of insurance coverage and limited perceived personal benefit of clinical verification as reasons for inaction. These findings suggest researchers will need to address barriers to seeking clinical verification in order to ensure that the intended benefits of returning genetic research results are realized. © 2017 The Authors. Molecular Genetics & Genomic Medicine published by Wiley Periodicals, Inc.

  16. Populating a Control Point Database: A cooperative effort between the USGS, Grand Canyon Monitoring and Research Center and the Grand Canyon Youth Organization

    Science.gov (United States)

    Brown, K. M.; Fritzinger, C.; Wharton, E.

    2004-12-01

    The Grand Canyon Monitoring and Research Center measures the effects of Glen Canyon Dam operations on the resources along the Colorado River from Glen Canyon Dam to Lake Mead in support of the Grand Canyon Adaptive Management Program. Control points are integral for geo-referencing the myriad of data collected in the Grand Canyon including aerial photography, topographic and bathymetric data used for classification and change-detection analysis of physical, biologic and cultural resources. The survey department has compiled a list of 870 control points installed by various organizations needing to establish a consistent reference for data collected at field sites along the 240 mile stretch of Colorado River in the Grand Canyon. This list is the foundation for the Control Point Database established primarily for researchers, to locate control points and independently geo-reference collected field data. The database has the potential to be a valuable mapping tool for assisting researchers to easily locate a control point and reduce the occurrance of unknowingly installing new control points within close proximity of an existing control point. The database is missing photographs and accurate site description information. Current site descriptions do not accurately define the location of the point but refer to the project that used the point, or some other interesting fact associated with the point. The Grand Canyon Monitoring and Research Center (GCMRC) resolved this problem by turning the data collection effort into an educational exercise for the participants of the Grand Canyon Youth organization. Grand Canyon Youth is a non-profit organization providing experiential education for middle and high school aged youth. GCMRC and the Grand Canyon Youth formed a partnership where GCMRC provided the logistical support, equipment, and training to conduct the field work, and the Grand Canyon Youth provided the time and personnel to complete the field work. Two data

  17. ISRIA statement: ten-point guidelines for an effective process of research impact assessment.

    Science.gov (United States)

    Adam, Paula; Ovseiko, Pavel V; Grant, Jonathan; Graham, Kathryn E A; Boukhris, Omar F; Dowd, Anne-Maree; Balling, Gert V; Christensen, Rikke N; Pollitt, Alexandra; Taylor, Mark; Sued, Omar; Hinrichs-Krapels, Saba; Solans-Domènech, Maite; Chorzempa, Heidi

    2018-02-08

    As governments, funding agencies and research organisations worldwide seek to maximise both the financial and non-financial returns on investment in research, the way the research process is organised and funded is becoming increasingly under scrutiny. There are growing demands and aspirations to measure research impact (beyond academic publications), to understand how science works, and to optimise its societal and economic impact. In response, a multidisciplinary practice called research impact assessment is rapidly developing. Given that the practice is still in its formative stage, systematised recommendations or accepted standards for practitioners (such as funders and those responsible for managing research projects) across countries or disciplines to guide research impact assessment are not yet available.In this statement, we propose initial guidelines for a rigorous and effective process of research impact assessment applicable to all research disciplines and oriented towards practice. This statement systematises expert knowledge and practitioner experience from designing and delivering the International School on Research Impact Assessment (ISRIA). It brings together insights from over 450 experts and practitioners from 34 countries, who participated in the school during its 5-year run (from 2013 to 2017) and shares a set of core values from the school's learning programme. These insights are distilled into ten-point guidelines, which relate to (1) context, (2) purpose, (3) stakeholders' needs, (4) stakeholder engagement, (5) conceptual frameworks, (6) methods and data sources, (7) indicators and metrics, (8) ethics and conflicts of interest, (9) communication, and (10) community of practice.The guidelines can help practitioners improve and standardise the process of research impact assessment, but they are by no means exhaustive and require evaluation and continuous improvement. The prima facie effectiveness of the guidelines is based on the systematised

  18. The Effects of Ability Grouping: A Meta-Analysis of Research Findings.

    Science.gov (United States)

    Noland, Theresa Koontz; Taylor, Bob L.

    The study reported in this paper quantitatively integrated the recent research findings on ability grouping in order to generalize about these effects on student achievement and student self-concept. Meta-analysis was used to statistically integrate the empirical data. The relationships among various experimental variables including grade level,…

  19. Strategic niche management and sustainable innovation journeys : theory, findings, research agenda, and policy

    NARCIS (Netherlands)

    Schot, J.W.; Geels, F.W.

    2008-01-01

    This article discusses empirical findings and conceptual elaborations of the last 10 years in strategic niche management research (SNM). The SNM approach suggests that sustainable innovation journeys can be facilitated by creating technological niches, i.e. protected spaces that allow the

  20. Programme Implementation in Social and Emotional Learning: Basic Issues and Research Findings

    Science.gov (United States)

    Durlak, Joseph A.

    2016-01-01

    This paper discusses the fundamental importance of achieving quality implementation when assessing the impact of social and emotional learning interventions. Recent findings in implementation science are reviewed that include a definition of implementation, its relation to programme outcomes, current research on the factors that affect…

  1. 75 FR 62892 - Massachusetts Institute of Technology Research Reactor Environmental Assessment and Finding of No...

    Science.gov (United States)

    2010-10-13

    ... NUCLEAR REGULATORY COMMISSION [Docket No. 50-020; NRC-2010-0313] Massachusetts Institute of Technology Research Reactor Environmental Assessment and Finding of No Significant Impact Correction In notice document 2010-24809 beginning on page 61220 in the issue of Monday, October 4, 2010, make the...

  2. Internet Consumer Catalog Shopping: Findings from an Exploratory Study and Directions for Future Research.

    Science.gov (United States)

    Jones, Joseph M.; Vijayasarathy, Leo R.

    1998-01-01

    Presents findings from an exploratory, empirical investigation of perceptions of Internet catalog shopping compared to more traditional print catalog shopping. Two factors that might influence perceptions, personality, and important other people are examined, and directions for further research are suggested. (Author/LRW)

  3. Plagiarism: Examination of Conceptual Issues and Evaluation of Research Findings on Using Detection Services

    Science.gov (United States)

    Konstantinidis, Angelos; Theodosiadou, Dimitra; Pappos, Christos

    2013-01-01

    The purpose of this review is to analyze and evaluate the research findings on using Plagiarism Detection Services (PDS) in universities. In order to do that, conceptual issues about plagiarism are examined and the complex nature of plagiarism is discussed. Subsequently, the pragmatic forms of student plagiarism are listed and PDS strategies on…

  4. Numerical methods for finding periodic points in discrete maps. High order islands chains and noble barriers in a toroidal magnetic configuration

    Energy Technology Data Exchange (ETDEWEB)

    Steinbrecher, G. [Association Euratom-Nasti Romania, Dept. of Theoretical Physics, Physics Faculty, University of Craiova (Romania); Reuss, J.D.; Misguich, J.H. [Association Euratom-CEA Cadarache, 13 - Saint-Paul-lez-Durance (France). Dept. de Recherches sur la Fusion Controlee

    2001-11-01

    We first remind usual physical and mathematical concepts involved in the dynamics of Hamiltonian systems, and namely in chaotic systems described by discrete 2D maps (representing the intersection points of toroidal magnetic lines in a poloidal plane in situations of incomplete magnetic chaos in Tokamaks). Finding the periodic points characterizing chains of magnetic islands is an essential step not only to determine the skeleton of the phase space picture, but also to determine the flux of magnetic lines across semi-permeable barriers like Cantori. We discuss here several computational methods used to determine periodic points in N dimensions, which amounts to solve a set of N nonlinear coupled equations: Newton method, minimization techniques, Laplace or steepest descend method, conjugated direction method and Fletcher-Reeves method. We have succeeded to improve this last method in an important way, without modifying its useful double-exponential convergence. This improved method has been tested and applied to finding periodic points of high order m in the 2D 'Tokamap' mapping, for values of m along rational chains of winding number n/m converging towards a noble value where a Cantorus exists. Such precise positions of periodic points have been used in the calculation of the flux across this Cantorus. (authors)

  5. Investigation and optimisation of mobile NaI(Tl) and 3He-based neutron detectors for finding point sources

    International Nuclear Information System (INIS)

    Nilsson, Jonas M.C.; Finck, Robert R.; Rääf, Christopher

    2015-01-01

    Neutron radiation produces high-energy gamma radiation through (n,γ) reactions in matter. This can be used to detect neutron sources indirectly using gamma spectrometers. The sensitivity of a gamma spectrometer to neutrons can be amplified by surrounding it with polyvinyl chloride (PVC). The hydrogen in the PVC acts as a moderator and the chlorine emits prompt gammas when a neutron is captured. A 4.7-l 3 He-based mobile neutron detector was compared to a 4-l NaI(Tl)-detector covered with PVC using this principle. Methods were also developed to optimise the measurement parameters of the systems. The detector systems were compared with regard to their ability to find 241 AmBe, 252 Cf and 238 Pu– 13 C neutron sources. Results from stationary measurements were used to calculate optimal integration times as well as minimum detectable neutron emission rates. It was found that the 3 He-based detector was more sensitive to 252 Cf sources whereas the NaI(Tl) detector was more sensitive to 241 AmBe and 238 Pu– 13 C sources. The results also indicated that the sensitivity of the detectors to sources at known distances could theoretically be improved by 60% by changing from fixed integration times to list mode in mobile surveys

  6. A systematic approach to find the best road map for enhancement of a power plant with dew point inlet air pre-cooling of the air compressor

    International Nuclear Information System (INIS)

    Sohani, Ali; Farasati, Yashar; Sayyaadi, Hoseyn

    2017-01-01

    Highlights: • Dew-point cooler was proposed in order to enhance a power plant. • A systematic method to find the best road map was offered. • Investigation was done considering four optimization scenarios and different investment plans. • Payback period of the final plan was 2.67 years. • Annual net power and steam generation’s capability were improved 6.02% and 8.92%. - Abstract: Dimensional characteristics and operating parameters of the optimized Maisotsenko indirect evaporative cooler for pre-cooling of the compressor’s inlet air and consequently enhancement of the gas-turbine power generation system as well as the best investment strategy for it were found for an in-operation combined cycle power plant through a systematic approach. Four optimization scenarios were proposed considering different combinations of annual average of net power of the gas-turbine power generation system, payback period time and enthalpy difference of exhaust gases compared to the reference state of each gas-turbine power generation system as objective functions. In each scenario, optimization was conducted for different possible percentages of investment allocated to the research and development of the project. After that, analytical hierarchy process was used to find the best percentage of investment allocated to the research and development of the project of each scenario and the final selected one. Having introduced the approach, it was implemented for Montazer-Ghaem combined cycle power plant in Iran. The results showed for that case study, the analytical hierarchy process selected an optimization scenario in which the annual average of the net power and the enthalpy difference of the exhaust gases compared to the reference state were the objective functions and 15% of the total profit of the gas-turbine power generation system sold electricity was dedicated to the improvement project. This optimization had the payback period time of 2.67 years and it also improved

  7. Finding the Middle Ground in Violent Video Game Research: Lessons From Ferguson (2015).

    Science.gov (United States)

    Markey, Patrick M

    2015-09-01

    Ferguson's comprehensive meta-analysis provides convincing data that violent video games have almost no effect on children's aggression. Although this finding is unlikely to bring unity to a divided field, Ferguson's article (2015, this issue) provides important rules that should aid all researchers. First, we need to be more accepting of results that are inconsistent with our own theories. Second, extraneous variables are often responsible for the relations previous studies have found between violent media and aggression. Third, we should avoid using unstandardized assessments of important variables whenever possible. Finally, caution is warranted when generalizing laboratory research findings to severe acts of violent in the "real world." It is hoped that, by accepting these basic rules, researchers and others will adopt less extreme positions concerning the effects of violent video games. © The Author(s) 2015.

  8. Building a Better Mousetrap: How Design-Based Research Was Used to Improve Homemade PowerPoint Games

    Science.gov (United States)

    Siko, Jason P.; Barbour, Michael K.

    2016-01-01

    This paper is a review of a three-cycle, design-based research study that explored the relationship between the pedagogical research and the actual implementation of a game design project using Microsoft PowerPoint. Much of the initial literature on using homemade PowerPoint games showed no significant improvement in test scores when students…

  9. Can We Trust Positive Findings of Intervention Research? The Role of Conflict of Interest.

    Science.gov (United States)

    Gorman, Dennis M

    2018-04-01

    In recent years, there has been increased attention to the issue of conflict of interest within prevention research. The aims of this paper are to discuss these developments and to relate them to discussions of conflict of interest in the broader scientific literature. Although there has been concern expressed about the extent to which conflicts of interest can be defined and measured, empirical research suggests that financial conflicts can be easily identified and assessed in meta-analyses focused on their effects on research quality. Research evidence also shows that conflict of interest is associated with use of flexible data analysis practices and the reporting of chance positive findings, both within prevention research and related disciplines such as public health and psychology. However, the overwhelming majority of published studies report positive results, and there are a number of other influences within academia (such as pressure to publish) that account for this and for the use of flexible data analysis practices. Accordingly, introducing measures to improve research quality in general, rather than just focusing on problems specific to research in which there is a clearly identifiable conflict of interest, may prove more effective and less controversial. Most such efforts focus on introducing greater transparency into research design, practice, and reporting. These both curtail employment of flexible data analysis practices and make their use transparent to investigators seeking to assess their effects on research quality. Also, requiring detailed disclosures of conflicts be reported by all investigators (not just senior authors) would improve current disclosure practices.

  10. Incidental findings in healthy control research subjects using whole-body MRI

    International Nuclear Information System (INIS)

    Morin, S.H.X.; Cobbold, J.F.L.; Lim, A.K.P.; Eliahoo, J.; Thomas, E.L.; Mehta, S.R.; Durighel, G.; Fitzpatrick, J.; Bell, J.D.

    2009-01-01

    Aim: Magnetic resonance imaging (MRI) is a powerful clinical tool used increasingly in the research setting. We aimed to assess the prevalence of incidental findings in a sequential cohort of healthy volunteers undergoing whole-body MRI as part of a normal control database for imaging research studies. Materials and methods: 148 healthy volunteers (median age 36 years, range 21-69 years; 63.5% males, 36.5% females) were enrolled into a prospective observational study at a single hospital-based MRI research unit in London, UK. Individuals with a clinical illness, treated or under investigation were excluded from the study. Results: 43 (29.1%) scans were abnormal with a total of 49 abnormalities detected. Of these, 20 abnormalities in 19 patients (12.8%) were of clinical significance. The prevalence of incidental findings increased significantly with both increasing age and body mass index (BMI). Obese subjects had a fivefold greater risk of having an incidental abnormality on MRI (OR 5.4, CI 2.1-14.0). Conclusions: This study showed that more than one quarter of healthy volunteers have MR-demonstrable abnormalities. There was an increased risk of such findings in obese patients. This has ethical and financial implications for future imaging research, particularly with respect to informed consent and follow-up of those with abnormalities detected during the course of imaging studies.

  11. How Chemistry Graduate Students and Researchers Are Finding and Using Chemical Information: Findings from Interviews in a Chinese University

    Science.gov (United States)

    Zhang, Yuening

    2017-01-01

    Although scholarship has addressed issues around serving international students in U.S. and Canadian libraries, reports on how Chinese graduate students use information in Chinese universities, especially for a particular discipline, are rare. In this study, the author interviewed 15 graduate students and researchers in a top-ranked chemistry…

  12. Embodiment of the interpersonal nexus: revealing qualitative research findings on shoulder surgery patients

    Directory of Open Access Journals (Sweden)

    Glass N

    2012-03-01

    qualitative findings in patient experiences of shoulder surgery.Keywords: interpersonal, qualitative research, pain management, patient experiences, shoulder surgery

  13. Bridges between multiple-point geostatistics and texture synthesis: Review and guidelines for future research

    Science.gov (United States)

    Mariethoz, Gregoire; Lefebvre, Sylvain

    2014-05-01

    Multiple-Point Simulations (MPS) is a family of geostatistical tools that has received a lot of attention in recent years for the characterization of spatial phenomena in geosciences. It relies on the definition of training images to represent a given type of spatial variability, or texture. We show that the algorithmic tools used are similar in many ways to techniques developed in computer graphics, where there is a need to generate large amounts of realistic textures for applications such as video games and animated movies. Similarly to MPS, these texture synthesis methods use training images, or exemplars, to generate realistic-looking graphical textures. Both domains of multiple-point geostatistics and example-based texture synthesis present similarities in their historic development and share similar concepts. These disciplines have however remained separated, and as a result significant algorithmic innovations in each discipline have not been universally adopted. Texture synthesis algorithms present drastically increased computational efficiency, patterns reproduction and user control. At the same time, MPS developed ways to condition models to spatial data and to produce 3D stochastic realizations, which have not been thoroughly investigated in the field of texture synthesis. In this paper we review the possible links between these disciplines and show the potential and limitations of using concepts and approaches from texture synthesis in MPS. We also provide guidelines on how recent developments could benefit both fields of research, and what challenges remain open.

  14. Topical review: sluggish cognitive tempo: research findings and relevance for pediatric psychology.

    Science.gov (United States)

    Becker, Stephen P

    2013-11-01

    To summarize recent research on sluggish cognitive tempo (SCT) and consider the potential relevance of SCT for the field of pediatric psychology. Literature review. Recent empirical evidence shows SCT symptoms consisting of sluggish/sleepy and daydreamy behaviors to be distinct from Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) Attention-Deficit/Hyperactivity Disorder (ADHD) symptoms. SCT is associated with psychosocial functioning in children and adolescents, including internalizing symptoms, social withdrawal, and, possibly, academic impairment. The recent findings reviewed suggest that SCT is an important construct for pediatric psychologists to be aware of and may also be directly useful for the research and practice of pediatric psychology.

  15. Communicating Academic Research Findings to IS Professionals: An Analysis of Problems

    Directory of Open Access Journals (Sweden)

    Michael Lang

    2003-01-01

    Full Text Available Because research findings often do not have direct or immediate relevance to IS professionals in industry, the question arises as to how those findings should be disseminated to them in a suitable form at such time as they do become relevant. A central argument of this paper is that the traditional mechanisms whereby academic researchers disseminate their work are prone to numerous communication breakdowns, and that much work which could potentially make valuable contributions to practice is haplessly lost within the vaults of academia. Using the well-known Shannon & Weaver communication model, three major problems are analyzed: the choice of dissemination channels, language barriers, and the alienation of academia from industry.

  16. Exploring the Best Practices of Nursing Research Councils in Magnet® Organizations: Findings From a Qualitative Research Study.

    Science.gov (United States)

    Day, Jennifer; Lindauer, Cathleen; Parks, Joyce; Scala, Elizabeth

    2017-05-01

    The objective of this descriptive qualitative study was to identify best practices of nursing research councils (NRCs) at Magnet®-designated hospitals. Nursing research (NR) is essential, adding to the body of nursing knowledge. Applying NR to the bedside improves care, enhances patient safety, and is an imperative for nursing leaders. We interviewed NR designees at 26 Magnet-recognized hospitals about the structure and function of their NRCs and used structural coding to identify best practices. Most organizations link NR and evidence-based practice. Council membership includes leadership and clinical nurses. Councils conduct scientific reviews for nursing studies, supporting nurse principal investigators. Tracking and reporting of NR vary widely and are challenging. Councils provide education, sponsor research days, and collaborate interprofessionally, including with academic partners. Findings from this study demonstrate the need to create formal processes to track and report NR and to develop outcome-focused NR education.

  17. Experimental study of radiation dose rate at different strategic points of the BAEC TRIGA Research Reactor.

    Science.gov (United States)

    Ajijul Hoq, M; Malek Soner, M A; Salam, M A; Haque, M M; Khanom, Salma; Fahad, S M

    2017-12-01

    The 3MW TRIGA Mark-II Research Reactor of Bangladesh Atomic Energy Commission (BAEC) has been under operation for about thirty years since its commissioning at 1986. In accordance with the demand of fundamental nuclear research works, the reactor has to operate at different power levels by utilizing a number of experimental facilities. Regarding the enquiry for safety of reactor operating personnel and radiation workers, it is necessary to know the radiation level at different strategic points of the reactor where they are often worked. In the present study, neutron, beta and gamma radiation dose rate at different strategic points of the reactor facility with reactor power level of 2.4MW was measured to estimate the rising level of radiation due to its operational activities. From the obtained results high radiation dose is observed at the measurement position of the piercing beam port which is caused by neutron leakage and accordingly, dose rate at the stated position with different reactor power levels was measured. This study also deals with the gamma dose rate measurements at a fixed position of the reactor pool top surface for different reactor power levels under both Natural Convection Cooling Mode (NCCM) and Forced Convection Cooling Mode (FCCM). Results show that, radiation dose rate is higher for NCCM in compared with FCCM and increasing with the increase of reactor power. Thus, concerning the radiological safety issues for working personnel and the general public, the radiation dose level monitoring and the experimental analysis performed within this paper is so much effective and the result of this work can be utilized for base line data and code verification of the nuclear reactor. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. A Mixed Method Research for Finding a Model of Administrative Decentralization

    OpenAIRE

    Tahereh Feizy; Alireza Moghali; Masuod Geramipoor; Reza Zare

    2015-01-01

    One of the critical issues of administrative decentralization in translating theory into practice is understanding its meaning. An important method to identify administrative decentralization is to address how it can be planned and implemented, and what are its implications, and how it would overcome challenges. The purpose of this study is finding a model for analyzing and evaluating administrative decentralization, so a mixed method research was used to explore and confirm the model of Admi...

  19. Return of individual research results and incidental findings in the clinical trials cooperative group setting.

    Science.gov (United States)

    Ferriere, Michael; Van Ness, Brian

    2012-04-01

    The National Cancer Institute (NCI)-funded cooperative group cancer clinical trial system develops experimental therapies and often collects samples from patients for correlative research. The cooperative group bank (CGB) system maintains biobanks with a current policy not to return research results to individuals. An online survey was created, and 10 directors of CGBs completed the surveys asking about understanding and attitudes in changing policies to consider return of incidental findings (IFs) and individual research results (IRRs) of health significance. The potential impact of the 10 consensus recommendations of Wolf et al. presented in this issue are examined. Reidentification of samples is often not problematic; however, changes to the current banking and clinical trial systems would require significant effort to fulfill an obligation of recontact of subjects. Additional resources, as well as a national advisory board would be required to standardize implementation.

  20. Assessing the effectiveness of a longitudinal knowledge dissemination intervention: Sharing research findings in rural South Africa

    Directory of Open Access Journals (Sweden)

    Rhian Twine

    2017-06-01

    Full Text Available Knowledge dissemination interventions (KDIs are integral to knowledge brokerage activities in research as part of the ethics of practice, but are seldom evaluated. In this case study, we critically reflect on an annual KDI as part of knowledge brokerage activities in the MRC/Wits-Agincourt Unit health and demographic surveillance system (HDSS in rural South Africa from 2001 to 2015. The HDSS findings on births, deaths and migrations, as well as nested research project results, were shared with villagers, village leaders and service providers. The data used for this case study comprised secondary analysis of 13 reports and 762 evaluation forms of annual village-based meetings; records of requests for data from stakeholders; and qualitative analysis of 15 individual and five focus group interviews with local leaders and service providers involving 60 people. Over time, the KDI evolved from taking place over one week a year to being extended over six months, and to include briefings with service providers and local leaders. Attendance at village-level meetings remained low at an average of 3 per cent of the total adult population. Since 2011, the KDI village-based meetings have developed into an embedded community forum for discussion of topical village issues. There has been a decrease in requests for health-care and other services from the research unit, with a concurrent increase in research-related questions and requests for data from service providers, village leaders and political representatives. We conclude that, in this setting, the dissemination of research findings is not a linear exchange of information from the researchers to village residents and their leadership, but is increasingly multi-directional. KDIs are a key component of knowledge brokerage activities and involve, influence and are influenced by other aspects of knowledge brokerage, such as identifying, engaging and connecting with stakeholders and supporting sustainability.

  1. Brands matter: Major findings from the Alcohol Brand Research Among Underage Drinkers (ABRAND) project.

    Science.gov (United States)

    Roberts, Sarah P; Siegel, Michael B; DeJong, William; Ross, Craig S; Naimi, Timothy; Albers, Alison; Skeer, Margie; Rosenbloom, David L; Jernigan, David H

    Alcohol research focused on underage drinkers has not comprehensively assessed the landscape of brand-level drinking behaviors among youth. This information is needed to profile youth alcohol use accurately, explore its antecedents, and develop appropriate interventions. We collected national data on the alcohol brand-level consumption of underage drinkers in the United States and then examined the association between those preferences and several factors including youth exposure to brand-specific alcohol advertising, corporate sponsorships, popular music lyrics, and social networking sites, and alcohol pricing. This paper summarizes our findings, plus the results of other published studies on alcohol branding and youth drinking. Our findings revealed several interesting facts regarding youth drinking. For example, we found that: 1) youth are not drinking the cheapest alcohol brands; 2) youth brand preferences differ from those of adult drinkers; 3) underage drinkers are not opportunistic in their alcohol consumption, but instead consume a very specific set of brands; 4) the brands that youth are heavily exposed to in magazines and television advertising correspond to the brands they most often report consuming; and 5) youth consume more of the alcohol brands to whose advertising they are most heavily exposed. The findings presented here suggests that brand-level alcohol research will provide important insight into youth drinking behaviors, the factors that contribute to youth alcohol consumption, and potential avenues for effective public health surveillance and programming.

  2. Top-cited publications on point-of-care ultrasound: The evolution of research trends.

    Science.gov (United States)

    Liao, Shao-Feng; Chen, Pai-Jung; Chaou, Chung-Hsien; Lee, Ching-Hsing

    2018-01-06

    Point-of-care ultrasound (POCUS) has been a rapidly growing and broadly used modality in recent decades. The purpose of this study was to determine how POCUS is incorporated into clinical medicine by analyzing trends of use in the published literature. POCUS-related publications were retrieved from the Web of Science (WoS) database. The search results were ranked according to the number of times an article was cited during three time frames and average annual number of citations. Of the top 100 most cited publications in the four rankings, information regarding the publication journal, publication year, first author's nationality, field of POCUS application, and number of times the article was cited was recorded for trend analysis. A total of 7860 POCUS-related publications were retrieved, and publications related to POCUS increased from 8 in 1990 to 754 in 2016. The top 148 cited publications from the four ranking groups were included in this study. Trauma was the leading application field in which POCUS was studied prior to 2001. After 2004, thorax, cardiovascular, and procedure-guidance were the leading fields in POCUS research. >79% (118/148) of the top-cited publications were conducted by authors in the United States, Italy, and France. The majority of publications were published in critical care medicine and emergency medicine journals. In recent years, publications relating to POCUS have increased. POCUS-related research has mainly been performed in thorax, cardiovascular, and procedure-guidance ultrasonography fields, replacing trauma as the major field in which POCUS was previously studied. Copyright © 2018 Elsevier Inc. All rights reserved.

  3. An algorithm for finding a common solution for a system of mixed equilibrium problem, quasi-variational inclusion problem and fixed point problem of nonexpansive semigroup

    Directory of Open Access Journals (Sweden)

    Liu Min

    2010-01-01

    Full Text Available In this paper, we introduce a hybrid iterative scheme for finding a common element of the set of solutions for a system of mixed equilibrium problems, the set of common fixed points for a nonexpansive semigroup and the set of solutions of the quasi-variational inclusion problem with multi-valued maximal monotone mappings and inverse-strongly monotone mappings in a Hilbert space. Under suitable conditions, some strong convergence theorems are proved. Our results extend some recent results in the literature.

  4. Application of research findings and summary of research needs: Bud Britton Memorial Symposium on Metabolic Disorders of Feedlot Cattle.

    Science.gov (United States)

    Galyean, M L; Eng, K S

    1998-01-01

    Updated research findings with acidosis, feedlot bloat, liver abscesses, and sudden death syndromes were presented at the Bud Britton Memorial Symposium on Metabolic Disorders of Feedlot Cattle. Possible industry applications include the need to establish guidelines for use of clostridial vaccines in feedlot cattle, further assessment of the relationship between acidosis and polioencephalomalacia, examination of the effects of various ionophores on the incidence of metabolic disorders, and evaluation of the effects of feed bunk management and limit- and restricted-feeding programs on the incidence of metabolic disorders. A multidisciplinary approach among researchers, consulting nutritionists and veterinarians, and feedlot managers will be required for effective progress in research and in the application of research findings. Areas suggested for further research include 1) assessment of feed consumption patterns and social behavior of cattle in large-pen, feedlot settings; 2) evaluation of the relationship between feed intake management systems (feed bunk management programs, limit- and programmed-feeding) and the incidence of metabolic disorders, including delineation of the role of variability in feed intake in the etiology of such disorders; 3) efforts to improve antemortem and postmortem diagnosis, and to establish standardized regional or national epidemiological databases for various metabolic disorders; 4) ascertaining the accuracy of diagnosis of metabolic disorders and determining the relationship of previous health history of animals to the incidence of metabolic disorders; 5) further defining ruminal and intestinal microbiology as it relates to metabolic disorders and deeper evaluation of metabolic changes that occur with such disorders; 6) continued appraisal of the effects of grain processing and specific feed ingredients and nutrients on metabolic disorders, and development of new feed additives to control or prevent these disorders; and 7

  5. PLUME-FEATHER, referencing and finding software for research and education

    International Nuclear Information System (INIS)

    Bénassy, O; Caron, C; Ferret-Canape, C; Cheylus, A; Courcelle, E; Dantec, C; Dayre, P; Dostes, T; Durand, A; Facq, A; Gambini, G; Morris, F; Geahchan, E; Helft, C; Hoffmann, D; Ingarao, M; Joly, P; Kieffer, J; Larré, J-M; Libes, M

    2014-01-01

    PLUME-FEATHER is a non-profit project created to Promote economicaL, Useful and Maintained softwarEFor theHigher Education And THE Research communities. The site references software, mainly Free/Libre Open Source Software (FLOSS) from French universities and national research organisations, (CNRS, INRA...), laboratories or departments as well as other FLOSS software used and evaluated by users within these institutions. Each software is represented by a reference card, which describes origin, aim, installation, cost (if applicable) and user experience from the point of view of an academic user for academic users. Presently over 1000 programs are referenced on PLUME by more than 900 contributors. Although the server is maintained by a French institution, it is open to international contributions in the academic domain. All contained and validated contents are visible to anonymous public, whereas (presently more than 2000) registered users can contribute, starting with comments on single software reference cards up to help with the organisation and presentation of the referenced software products. The project has been presented to the HEP community in 2012 for the first time [1]. This is an update of the status and a call for (further) contributions.

  6. PLUME-FEATHER, Referencing and Finding Software for Research and Education

    Science.gov (United States)

    Bénassy, O.; Caron, C.; Ferret-Canape, C.; Cheylus, A.; Courcelle, E.; Dantec, C.; Dayre, P.; Dostes, T.; Durand, A.; Facq, A.; Gambini, G.; Geahchan, E.; Helft, C.; Hoffmann, D.; Ingarao, M.; Joly, P.; Kieffer, J.; Larré, J.-M.; Libes, M.; Morris, F.; Parmentier, H.; Pérochon, L.; Porte, O.; Romier, G.; Rousse, D.; Tournoy, R.; Valeins, H.

    2014-06-01

    PLUME-FEATHER is a non-profit project created to Promote economicaL, Useful and Maintained softwarEFor theHigher Education And THE Research communities. The site references software, mainly Free/Libre Open Source Software (FLOSS) from French universities and national research organisations, (CNRS, INRA...), laboratories or departments as well as other FLOSS software used and evaluated by users within these institutions. Each software is represented by a reference card, which describes origin, aim, installation, cost (if applicable) and user experience from the point of view of an academic user for academic users. Presently over 1000 programs are referenced on PLUME by more than 900 contributors. Although the server is maintained by a French institution, it is open to international contributions in the academic domain. All contained and validated contents are visible to anonymous public, whereas (presently more than 2000) registered users can contribute, starting with comments on single software reference cards up to help with the organisation and presentation of the referenced software products. The project has been presented to the HEP community in 2012 for the first time [1]. This is an update of the status and a call for (further) contributions.

  7. PLUME–FEATHER, Referencing and Finding Software for Research and Education

    International Nuclear Information System (INIS)

    Hoffmann, Dirk; Romier, Geneviève

    2012-01-01

    PLUME-FEATHER is a non-profit project created to Promote economicaL, Useful and Maintained softwarE For the Higher Education And THE Research communities. The site references software, mainly Free/Libre Open Source Software (FLOSS) from French universities and national research organisations, (CNRS, INRA…), laboratories or departments as well as other FLOSS software used and evaluated by users within these institutions. Each software is represented by a reference card, which describes origin, aim, installation, cost (if applicable) and user experience from the point of view of an academic user for academic users. Presently over 1000 programs are referenced on PLUME. Although the server is maintained by a french institution, it is completely open to international contributions in the academic domainb. All contained and validated contents are visible to anonymous public, whereas registered users can contribute, starting with comments on single software reference cards up to help with the organisation and presentation of the referenced software products. This first presentation is call for (further) contributions from the HEP community.

  8. Using Interactive Technology to Disseminate Research Findings to a Diverse Population

    Directory of Open Access Journals (Sweden)

    Denise Stockley

    2009-09-01

    Full Text Available This paper demonstrates how case stories can be used to disseminate the findings of several case studies on negotiating accommodations in the workplace. It highlights the power of interactive technology and of the partnership between the researchers and the Canadian Council for Rehabilitation and Work (CCRW. The paper describes the process of designing an interactive web-based case story for the purpose of disseminating research findings. The interactive case story is an extension of both the case study and the narrative case story. As part of a larger research project, it is our goal to use interactive case stories to investigate the impact of essential skills training on workers with disabilities who negotiate with employers for workplace accommodations. Résumé Le présent article montre comment les histoires de cas peuvent être utilisées pour diffuser les conclusions de plusieurs études de cas sur la négociation entourant l’aménagement du milieu de travail. Il met en évidence le pouvoir de la technologie interactive et du partenariat entre les chercheurs et le Conseil canadien de la réadaptation et du travail (CCRT. L’article décrit le processus de conception d’une histoire de cas interactive en ligne visant à diffuser des résultats de recherche. L’histoire de cas interactive est un prolongement à la fois de l’étude de cas et du récit de l’histoire de cas. Dans le cadre d’un plus vaste projet de recherche, notre but est d’utiliser des histoires de cas interactives pour étudier l’impact de la formation sur les compétences essentielles chez les travailleurs handicapés qui négocient avec leur employeur pour l’aménagement de leur milieu de travail.

  9. Human Performance Optimization Metrics: Consensus Findings, Gaps, and Recommendations for Future Research.

    Science.gov (United States)

    Nindl, Bradley C; Jaffin, Dianna P; Dretsch, Michael N; Cheuvront, Samuel N; Wesensten, Nancy J; Kent, Michael L; Grunberg, Neil E; Pierce, Joseph R; Barry, Erin S; Scott, Jonathan M; Young, Andrew J; OʼConnor, Francis G; Deuster, Patricia A

    2015-11-01

    Human performance optimization (HPO) is defined as "the process of applying knowledge, skills and emerging technologies to improve and preserve the capabilities of military members, and organizations to execute essential tasks." The lack of consensus for operationally relevant and standardized metrics that meet joint military requirements has been identified as the single most important gap for research and application of HPO. In 2013, the Consortium for Health and Military Performance hosted a meeting to develop a toolkit of standardized HPO metrics for use in military and civilian research, and potentially for field applications by commanders, units, and organizations. Performance was considered from a holistic perspective as being influenced by various behaviors and barriers. To accomplish the goal of developing a standardized toolkit, key metrics were identified and evaluated across a spectrum of domains that contribute to HPO: physical performance, nutritional status, psychological status, cognitive performance, environmental challenges, sleep, and pain. These domains were chosen based on relevant data with regard to performance enhancers and degraders. The specific objectives at this meeting were to (a) identify and evaluate current metrics for assessing human performance within selected domains; (b) prioritize metrics within each domain to establish a human performance assessment toolkit; and (c) identify scientific gaps and the needed research to more effectively assess human performance across domains. This article provides of a summary of 150 total HPO metrics across multiple domains that can be used as a starting point-the beginning of an HPO toolkit: physical fitness (29 metrics), nutrition (24 metrics), psychological status (36 metrics), cognitive performance (35 metrics), environment (12 metrics), sleep (9 metrics), and pain (5 metrics). These metrics can be particularly valuable as the military emphasizes a renewed interest in Human Dimension efforts

  10. Disclosing incidental findings in brain research: the rights of minors in decision-making.

    Science.gov (United States)

    Di Pietro, Nina C; Illes, Judy

    2013-11-01

    MRI is used routinely in research with children to generate new knowledge about brain development. The detection of unexpected brain abnormalities (incidental findings; IFs) in these studies presents unique challenges. While key issues surrounding incidence and significance, duty of care, and burden of disclosure have been addressed substantially for adults, less empirical data and normative analyses exist for minors who participate in minimal risk research. To identify ethical concerns and fill existing gaps, we conducted a comprehensive review of papers that focused explicitly on the discovery of IFs in minors. The discourse in the 21 papers retrieved for this analysis amply covered practical issues such as informed consent and screening, difficulties in ascertaining clinical significance, the economic costs and burden of responsibility on researchers, and risks (physical or psychological). However, we found little discussion about the involvement of minors in decisions about disclosure of IFs in the brain, especially for IFs of low clinical significance. In response, we propose a framework for managing IFs that integrates practical considerations with explicit appreciation of rights along the continuum of maturity. This capacity-adjusted framework emphasizes the importance of involving competent minors and respecting their right to make decisions about disclosure. Copyright © 2013 Wiley Periodicals, Inc.

  11. [Research on infrared radiation characteristics of skin covering two acupuncture points in the hand and forearm, NeiGuan and LaoGong points].

    Science.gov (United States)

    Wang, Zhen; Yu, Wenlong; Cui, Han; Shi, Huafeng; Jin, Lei

    2013-06-01

    In order to research the infrared radiation characteristics of the skin covering Traditional Chinese acupuncture points, which are NeiGuan in the forearm and LaoGong in the center of the palm, we detected continuously the infrared radiation spectra of the human body surface by using Fourier Transform Infrared Spectroscopy. The experimental results showed that firstly, the differences of the infrared radiation spectra of the human body surface were obvious between individuals. Secondly, the infrared radiation intensity of the human body surface changed with time changing. The infrared radiation intensity in two special wavelength ranges (wavelengths from 6. 79 microm to 6. 85 microm and from 13. 6 microm to 14. 0 microm) changed much more than that in other ranges obviously. Thirdly, the proportions of the infrared radiation spectra changed, which were calculated from the spectra of two different aupuncture points, were same in these two special wavelength ranges, but their magnitude changes were different. These results suggested that the infrared radiation of acupuncture points have the same biological basis, and the mechanism of the infrared radiation in these two special wavelength ranges is different from other tissue heat radiation.

  12. Strengthening government health and family planning programs: findings from an action research project in rural Bangladesh.

    Science.gov (United States)

    Simmons, R; Phillips, J F; Rahman, M

    1984-01-01

    An ongoing study at the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B) is based on the premise that public sector health and family planning programs can be improved through an assessment of the dysfunctional aspects of their operations, the development of problem-solving capabilities, and the transfer of strategies successfully tested in a small-scale pilot project. This paper reports findings from a field trial implemented in a subunit of the project area at an early stage of the project. Operational barriers to public sector program implementation are discussed with regard to the quantity of work, the quality of work, supplies and facilities, integration of health and family planning, and leadership, supervision, and decision making. Initial results of the ICDDR,B intervention on these managerial processes are also indicated.

  13. Findings from working for the IAEA initiative on research reactor ageing and ageing management

    International Nuclear Information System (INIS)

    Roegler, H.-J.

    2010-01-01

    1995 the last sharing and compiling the existing knowledge about of the Research Reactor (RR) Ageing and the respective Fighting took place during a well attended conference at Geesthacht, Germany, documented in a bulky conference report. In 2008, the International Atomic Energy Agency has initiated another collecting and evaluating in order to make the recent experience in that field available to the entire RR Community. In this respect, RR operators, plant and system fabricators, and authorities as well as independent experts have been approached worldwide for providing contributions and fortunately about every second member of the RR Community replied. The paper is going to inform on the experience gained by the contacts and communication, the replies as well as the non-replies, underlying motives as problems, and mainly, some statistical evaluation of the findings. The respective IAEA data base being accessible to all members of the RR Community will be briefly characterised in structures and contents. (author)

  14. Trust in leadership: meta-analytic findings and implications for research and practice.

    Science.gov (United States)

    Dirks, Kurt T; Ferrin, Donald L

    2002-08-01

    In this study, the authors examined the findings and implications of the research on trust in leadership that has been conducted during the past 4 decades. First, the study provides estimates of the primary relationships between trust in leadership and key outcomes, antecedents, and correlates (k = 106). Second, the study explores how specifying the construct with alternative leadership referents (direct leaders vs. organizational leadership) and definitions (types of trust) results in systematically different relationships between trust in leadership and outcomes and antecedents. Direct leaders (e.g., supervisors) appear to be a particularly important referent of trust. Last, a theoretical framework is offered to provide parsimony to the expansive literature and to clarify the different perspectives on the construct of trust in leadership and its operation.

  15. Cross-pollination of research findings, although uncommon, may accelerate discovery of human disease genes

    Directory of Open Access Journals (Sweden)

    Duda Marlena

    2012-11-01

    Full Text Available Abstract Background Technological leaps in genome sequencing have resulted in a surge in discovery of human disease genes. These discoveries have led to increased clarity on the molecular pathology of disease and have also demonstrated considerable overlap in the genetic roots of human diseases. In light of this large genetic overlap, we tested whether cross-disease research approaches lead to faster, more impactful discoveries. Methods We leveraged several gene-disease association databases to calculate a Mutual Citation Score (MCS for 10,853 pairs of genetically related diseases to measure the frequency of cross-citation between research fields. To assess the importance of cooperative research, we computed an Individual Disease Cooperation Score (ICS and the average publication rate for each disease. Results For all disease pairs with one gene in common, we found that the degree of genetic overlap was a poor predictor of cooperation (r2=0.3198 and that the vast majority of disease pairs (89.56% never cited previous discoveries of the same gene in a different disease, irrespective of the level of genetic similarity between the diseases. A fraction (0.25% of the pairs demonstrated cross-citation in greater than 5% of their published genetic discoveries and 0.037% cross-referenced discoveries more than 10% of the time. We found strong positive correlations between ICS and publication rate (r2=0.7931, and an even stronger correlation between the publication rate and the number of cross-referenced diseases (r2=0.8585. These results suggested that cross-disease research may have the potential to yield novel discoveries at a faster pace than singular disease research. Conclusions Our findings suggest that the frequency of cross-disease study is low despite the high level of genetic similarity among many human diseases, and that collaborative methods may accelerate and increase the impact of new genetic discoveries. Until we have a better

  16. Some recent research findings on the social dynamics of environmental risk perception

    International Nuclear Information System (INIS)

    Horlick-Jones, T.; Marchi, B. de; Del Zotto, M.; Pellizzoni, L.; Ungaro, D.; Prades Lopez, A.; Diaz Hidalgo, M.; Pidgeon, N.; Sime, J.

    1998-01-01

    Full text of publication follows: key themes: social dynamics of public risk perception; trust, tolerability, and risk management; discourses of environmental risk; implications for risk communication and environmental valuation; application of mixed qualitative/quantitative methods in risk perception research. This paper presents some of the key findings of a two-year comparative European study (the PRISP Project) on public perception of risks associated with industrial sites in the UK, Italy and Spain. The project utilised a mixed-method approach (comprising community ethnography, semi-structured interviews, questionnaire survey and focus groups), within a Grounded Theory framework, to examine the social dynamics of risk comprehension, tolerability and politics in settings adjacent to a range of industrial facilities. These often complex industrial zones present a portfolio of 'acute' and 'chronic' risks including hazards associated with sites regulated by the European Union COMAH Directive. Our findings have important implications for the regulation of both major accident hazard and pollution risks, risk communication programmes, industrial risk management practices and for the methodological basis of health and safety and environmental valuation techniques. (authors)

  17. RESEARCH ON FEATURE POINTS EXTRACTION METHOD FOR BINARY MULTISCALE AND ROTATION INVARIANT LOCAL FEATURE DESCRIPTOR

    Directory of Open Access Journals (Sweden)

    Hongwei Ying

    2014-08-01

    Full Text Available An extreme point of scale space extraction method for binary multiscale and rotation invariant local feature descriptor is studied in this paper in order to obtain a robust and fast method for local image feature descriptor. Classic local feature description algorithms often select neighborhood information of feature points which are extremes of image scale space, obtained by constructing the image pyramid using certain signal transform method. But build the image pyramid always consumes a large amount of computing and storage resources, is not conducive to the actual applications development. This paper presents a dual multiscale FAST algorithm, it does not need to build the image pyramid, but can extract feature points of scale extreme quickly. Feature points extracted by proposed method have the characteristic of multiscale and rotation Invariant and are fit to construct the local feature descriptor.

  18. The Research and Application of SURF Algorithm Based on Feature Point Selection Algorithm

    Directory of Open Access Journals (Sweden)

    Zhang Fang Hu

    2014-04-01

    Full Text Available As the pixel information of depth image is derived from the distance information, when implementing SURF algorithm with KINECT sensor for static sign language recognition, there can be some mismatched pairs in palm area. This paper proposes a feature point selection algorithm, by filtering the SURF feature points step by step based on the number of feature points within adaptive radius r and the distance between the two points, it not only greatly improves the recognition rate, but also ensures the robustness under the environmental factors, such as skin color, illumination intensity, complex background, angle and scale changes. The experiment results show that the improved SURF algorithm can effectively improve the recognition rate, has a good robustness.

  19. The Role of Serotonin (5-HT) in Behavioral Control: Findings from Animal Research and Clinical Implications

    Science.gov (United States)

    Sanchez, CL; Biskup, CS; Herpertz, S; Gaber, TJ; Kuhn, CM; Hood, SH

    2015-01-01

    The neurotransmitters serotonin and dopamine both have a critical role in the underlying neurobiology of different behaviors. With focus on the interplay between dopamine and serotonin, it has been proposed that dopamine biases behavior towards habitual responding, and with serotonin offsetting this phenomenon and directing the balance toward more flexible, goal-directed responding. The present focus paper stands in close relationship to the publication by Worbe et al. (2015), which deals with the effects of acute tryptophan depletion, a neurodietary physiological method to decrease central nervous serotonin synthesis in humans for a short period of time, on the balance between hypothetical goal-directed and habitual systems. In that research, acute tryptophan depletion challenge administration and a following short-term reduction in central nervous serotonin synthesis were associated with a shift of behavioral performance towards habitual responding, providing further evidence that central nervous serotonin function modulates the balance between goal-directed and stimulus-response habitual systems of behavioral control. In the present focus paper, we discuss the findings by Worbe and colleagues in light of animal experiments as well as clinical implications and discuss potential future avenues for related research. PMID:25991656

  20. Rape treatment outcome research: empirical findings and state of the literature.

    Science.gov (United States)

    Vickerman, Katrina A; Margolin, Gayla

    2009-07-01

    This article reviews empirical support for treatments targeting women sexually assaulted during adolescence or adulthood. Thirty-two articles were located using data from 20 separate samples. Of the 20 samples, 12 targeted victims with chronic symptoms, three focused on the acute period post-assault, two included women with chronic and acute symptoms, and three were secondary prevention programs. The majority of studies focus on posttraumatic stress disorder (PTSD), depression, and/or anxiety as treatment targets. Cognitive Processing Therapy and Prolonged Exposure have garnered the most support with this population. Stress Inoculation Training and Eye Movement Desensitization and Reprocessing also show some efficacy. Of the four studies that compared active treatments, few differences were found. Overall, cognitive behavioral interventions lead to better PTSD outcomes than supportive counseling does. However, even in the strongest treatments more than one-third of women retain a PTSD diagnosis at post-treatment or drop out of treatment. Discussion highlights the paucity of research in this area, methodological limitations of examined studies, generalizability of findings, and important directions for future research at various stages of trauma recovery.

  1. Findings by the Commission Evaluating Nuclear Safety and Repository Research in Germany

    International Nuclear Information System (INIS)

    Sandtner, W.; Closs, K.D.

    2000-01-01

    The Commission Evaluating Nuclear Safety and Repository Research in Germany, which had been appointed by the German Federal Ministry of Economics on September 24, 1999, submitted its report. Here is the gist of the Commission's findings: Irrespective of the criteria established with the political decision to terminate the use of nuclear power in Germany, competence in nuclear safety must be maintained over the next few decades. Only in this way can the government perform its duty and make provisions for the future, and can the safety of nuclear facilities and waste management pathways be ensured in accordance with the international state of the art. In view of the considerable reduction in funding in recent years and also in future, measures must be taken to ensure that further decreases in-roject funding and institutionalized government financing are excluded so as to avoid further declines in terms of manpower and competence in this field. Reactor safety and repository research must be financed at a level allowing the federal government to discharge its legal duties. The full report by the Commission, with its annexes, is available on the GRS web site (http://www.grs.de) as a PDF file. (orig.) [de

  2. Institutional review board perspectives on obligations to disclose genetic incidental findings to research participants.

    Science.gov (United States)

    Gliwa, Catherine; Yurkiewicz, Ilana R; Lehmann, Lisa Soleymani; Hull, Sara Chandros; Jones, Nathan; Berkman, Benjamin E

    2016-07-01

    Researchers' obligations to disclose genetic incidental findings (GIFs) have been widely debated, but there has been little empirical study of the engagement of institutional review boards (IRBs) with this issue. This article presents data from the first extensive (n = 796) national survey of IRB professionals' understanding of, experience with, and beliefs surrounding GIFs. Most respondents had dealt with questions about GIFs (74%), but only a minority (47%) felt prepared to address them. Although a majority believed that there is an obligation to disclose GIFs (78%), there is still not consensus about the supporting ethical principles. Respondents generally did not endorse the idea that researchers' additional time and effort (7%), and lack of resources (29%), were valid reasons for diminishing a putative obligation. Most (96%) supported a right not to know, but this view became less pronounced (63%) when framed in terms of specific case studies. IRBs are actively engaged with GIFs but have not yet reached consensus. Respondents were uncomfortable with arguments that could be used to limit an obligation to return GIFs. This could indicate that IRBs are providing some of the impetus for the trend toward returning GIFs, although questions remain about the relative contribution of other stakeholders.Genet Med 18 7, 705-711.

  3. Rape Treatment Outcome Research: Empirical Findings and State of the Literature

    Science.gov (United States)

    Vickerman, Katrina A.; Margolin, Gayla

    2009-01-01

    This article reviews empirical support for treatments targeting women sexually assaulted during adolescence or adulthood. Thirty-two articles were located using data from 20 separate samples. Of the 20 samples, 12 targeted victims with chronic symptoms, three focused on the acute period post-assault, two included women with chronic and acute symptoms, and three were secondary prevention programs. The majority of studies focus on posttraumatic stress disorder (PTSD), depression, and/or anxiety as treatment targets. Cognitive Processing Therapy and Prolonged Exposure have garnered the most support with this population. Stress Inoculation Training and Eye Movement Desensitization and Reprocessing also show some efficacy. Of the four studies that compared active treatments, few differences were found. Overall, cognitive behavioral interventions lead to better PTSD outcomes than supportive counseling does. However, even in the strongest treatments more than one-third of women retain a PTSD diagnosis at post-treatment or drop out of treatment. Discussion highlights the paucity of research in this area, methodological limitations of examined studies, generalizability of findings, and important directions for future research at various stages of trauma recovery. PMID:19442425

  4. Recruiting community health centers into pragmatic research: Findings from STOP CRC.

    Science.gov (United States)

    Coronado, Gloria D; Retecki, Sally; Schneider, Jennifer; Taplin, Stephen H; Burdick, Tim; Green, Beverly B

    2016-04-01

    uninsured patients, limited clinic capacity to prepare mailings required by the study protocol, discomfort with randomization, and concerns about delaying program implementation at some clinics due to the research requirements. Our findings address an important research gap and may inform future efforts to recruit community health centers into pragmatic research. © The Author(s) 2015.

  5. Visitor’s Guide to Oliktok Point Atmospheric Radiation Measurement Climate Research Facility, North Slope of Alaska

    Energy Technology Data Exchange (ETDEWEB)

    Desilets, Darin [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Helsel, Fred M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Bendure, Al O. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lucero, Daniel A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Ivey, Mark D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Dexheimer, Danielle N. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-04-01

    The importance of Oliktok Point, Alaska, as a focal point for climate research in the Arctic continues to grow with the addition of a U.S. Department of Energy (DOE) Atmospheric Radiation Monitoring (ARM) Climate Research Facility Mobile Facility (AMF) and the expansion of infrastructure to support airborne measurements. The site hosts a suite of instruments for making multi-year, high-fidelity atmospheric measurements; serves as a base of operations for field campaigns; and contains the only Restricted Airspace and Warning Area in the U.S. Arctic, which enables the use of unmanned aircraft systems. The use of this site by climate researchers involves several considerations, including its remoteness, harsh climate, and location amid the North Slope oilfields. This guide is intended to help visitors to Oliktok Point navigate this unique physical and administrative environment, and thereby facilitate safe and productive operations.

  6. [Analysis and research on cleaning points of HVAC systems in public places].

    Science.gov (United States)

    Yang, Jiaolan; Han, Xu; Chen, Dongqing; Jin, Xin; Dai, Zizhu

    2010-03-01

    To analyze cleaning points of HVAC systems, and to provides scientific base for regulating the cleaning of HVAC systems. Based on the survey results on the cleaning situation of HVAC systems around China for the past three years, we analyzes the cleaning points of HVAC systems from various aspects, such as the major health risk factors of HVAC systems, the formulation strategy of the cleaning of HVAC systems, cleaning methods and acceptance points of the air ducts and the parts of HVAC systems, the onsite protection and individual protection, the waste treatment and the cleaning of the removed equipment, inspection of the cleaning results, video record, and the final acceptance of the cleaning. The analysis of the major health risk factors of HVAC systems and the formulation strategy of the cleaning of HVAC systems is given. The specific methods for cleaning the air ducts, machine units, air ports, coil pipes and the water cooling towers of HVAC systems, the acceptance points of HVAC systems and the requirements of the report on the final acceptance of the cleaning of HVAC systems are proposed. By the analysis of the points of the cleaning of HVAC systems and proposal of corresponding measures, this study provides the base for the scientific and regular launch of the cleaning of HVAC systems, a novel technology service, and lays a foundation for the revision of the existing cleaning regulations, which may generate technical and social benefits to some extent.

  7. Research on point source simulating the γ-ray detection efficiencies of stander source

    International Nuclear Information System (INIS)

    Tian Zining; Jia Mingyan; Shen Maoquan; Yang Xiaoyan; Cheng Zhiwei

    2010-01-01

    For φ 75 mm x 25 mm sample, the full energy peak efficiencies on different heights of sample radius were obtained using the point sources, and the function parameters about the full energy peak efficiencies of point sources based on radius was fixed. The 59.54 keV γ-ray, 661.66 keV γ-ray, 1173.2 keV γ-ray, 1332.5 keV γ-ray detection efficiencies on different height of samples were obtained, based on the full energy peak efficiencies of point sources and its height, and the function parameters about the full energy peak efficiencies of surface sources based on sample height was fixed. The detection efficiency of (75 mm x 25 mm calibration source can be obtained by integrality, the detection efficiencies simulated by point sources are consistent with the results of stander source in 10%. Therefore, the calibration method of stander source can be substituted by the point source simulation method, and it tis feasible when there is no stander source.) (authors)

  8. Research of generation mechanism of plasma points in Z-pinch

    Energy Technology Data Exchange (ETDEWEB)

    Afonin, V I; Garafov, A M; Kovalev, V P; Ostashev, V I; Potapov, A V [All-Russian Research Inst. of Technical Physics, Snezhinsk (Russian Federation); Lazarchuk, V P; Petrov, S I [All-Russian Scientific Research Inst. of Experimental Physics, Sarov (Russian Federation)

    1997-12-31

    The results of experimental investigations of hot points formed at explosion of thin aluminium wires are reported. The experiments were performed at the fast high-current pulsed generator SIGNAL, which was modernized with the purpose to increase the load current up to 210 kA. The parameters of the plasma in hot points were determined on the base of analysis of the recorded soft x-ray spectra. The estimated electron temperature lies within the range of 0.4-0.9 keV, and the electron density reaches the value of 1023 cm-3. Certain contradictions following from the analysis of the measured data might be caused by significant temperature and density gradients in the hot points. It is shown that the experimental results can be most completely interpreted within the framework of the radiation compression model. (J.U.). 3 figs., 7 refs.

  9. Centralized adjudication of cardiovascular end points in cardiovascular and noncardiovascular pharmacologic trials: a report from the Cardiac Safety Research Consortium.

    Science.gov (United States)

    Seltzer, Jonathan H; Turner, J Rick; Geiger, Mary Jane; Rosano, Giuseppe; Mahaffey, Kenneth W; White, William B; Sabol, Mary Beth; Stockbridge, Norman; Sager, Philip T

    2015-02-01

    This white paper provides a summary of presentations and discussions at a cardiovascular (CV) end point adjudication think tank cosponsored by the Cardiac Safety Research Committee and the US Food and Drug Administration (FDA) that was convened at the FDA's White Oak headquarters on November 6, 2013. Attention was focused on the lack of clarity concerning the need for end point adjudication in both CV and non-CV trials: there is currently an absence of widely accepted academic or industry standards and a definitive regulatory policy on how best to structure and use clinical end point committees (CECs). This meeting therefore provided a forum for leaders in the fields of CV clinical trials and CV safety to develop a foundation of initial best practice recommendations for use in future CEC charters. Attendees included representatives from pharmaceutical companies, regulatory agencies, end point adjudication specialist groups, clinical research organizations, and active, academically based adjudicators. The manuscript presents recommendations from the think tank regarding when CV end point adjudication should be considered in trials conducted by cardiologists and by noncardiologists as well as detailing key issues in the composition of a CEC and its charter. In addition, it presents several recommended best practices for the establishment and operation of CECs. The science underlying CV event adjudication is evolving, and suggestions for additional areas of research will be needed to continue to advance this science. This manuscript does not constitute regulatory guidance. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. Source memory errors in schizophrenia, hallucinations and negative symptoms: a synthesis of research findings.

    Science.gov (United States)

    Brébion, G; Ohlsen, R I; Bressan, R A; David, A S

    2012-12-01

    Previous research has shown associations between source memory errors and hallucinations in patients with schizophrenia. We bring together here findings from a broad memory investigation to specify better the type of source memory failure that is associated with auditory and visual hallucinations. Forty-one patients with schizophrenia and 43 healthy participants underwent a memory task involving recall and recognition of lists of words, recognition of pictures, memory for temporal and spatial context of presentation of the stimuli, and remembering whether target items were presented as words or pictures. False recognition of words and pictures was associated with hallucination scores. The extra-list intrusions in free recall were associated with verbal hallucinations whereas the intra-list intrusions were associated with a global hallucination score. Errors in discriminating the temporal context of word presentation and the spatial context of picture presentation were associated with auditory hallucinations. The tendency to remember verbal labels of items as pictures of these items was associated with visual hallucinations. Several memory errors were also inversely associated with affective flattening and anhedonia. Verbal and visual hallucinations are associated with confusion between internal verbal thoughts or internal visual images and perception. In addition, auditory hallucinations are associated with failure to process or remember the context of presentation of the events. Certain negative symptoms have an opposite effect on memory errors.

  11. Religion, spirituality, and medicine: research findings and implications for clinical practice.

    Science.gov (United States)

    Koenig, Harold G

    2004-12-01

    A growing body of scientific research suggests connections between religion, spirituality, and both mental and physical health. The findings are particularly strong in patients with severe or chronic illnesses who are having stressful psychologic and social changes, as well as existential struggles related to meaning and purpose. Recent studies indicate that religious beliefs influence medical decisions, such as the use of chemotherapy and other life-saving treatments, and at times may conflict with medical care. This article addresses the ways physicians can use such information. Spirituality is an area that makes many physicians uncomfortable, since training in medical schools and continuing medical education programs are limited. Not only do most physicians lack the necessary training, they worry about spending additional time with patients and overstepping ethical boundaries. While these concerns are valid, each can be addressed in a sensible way. Taking a spiritual history, supporting the patient's beliefs, and orchestrating the fulfillment of spiritual needs are among the topics this article will address. The goal is to help physicians provide medical care that is sensitive to the way many patients understand and cope with medical illness.

  12. Frontal alpha asymmetry as a pathway to behavioural withdrawal in depression: Research findings and issues.

    Science.gov (United States)

    Jesulola, Emmanuel; Sharpley, Christopher F; Bitsika, Vicki; Agnew, Linda L; Wilson, Peter

    2015-10-01

    Depression has been described as a process of behavioural withdrawal from overwhelming aversive stressors, and which manifests itself in the diagnostic symptomatology for Major Depressive Disorder (MDD). The underlying neurobiological pathways to that behavioural withdrawal are suggested to include greater activation in the right vs the left frontal lobes, described as frontal EEG asymmetry. However, despite a previous meta-analysis that provided overall support for this EEG asymmetry hypothesis, inconsistencies and several methodological confounds exist. The current review examines the literature on this issue, identifies inconsistencies in findings and discusses several key research issues that require addressing for this field to move towards a defensible theoretical model of depression and EEG asymmetry. In particular, the position of EEG asymmetry in the brain, measurement of severity and symptoms profiles of depression, and the effects of gender are considered as potential avenues to more accurately define the specific nature of the depression-EEG asymmetry association. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Problems Teachers Face When Doing Action Research and Finding Possible Solutions: Three Cases

    Science.gov (United States)

    Zhou, Jun

    2012-01-01

    Through case studies, this paper explores problems teachers face when doing action research: for instance, teachers may misunderstand the research, mistrust university researchers, lack the time or adequate library resources to conduct research, lack theoretical guidance or knowledge of research methodology, and feel pressure or frustration during…

  14. Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science

    Directory of Open Access Journals (Sweden)

    Alexander Jeffery A

    2009-08-01

    Full Text Available Abstract Background Many interventions found to be effective in health services research studies fail to translate into meaningful patient care outcomes across multiple contexts. Health services researchers recognize the need to evaluate not only summative outcomes but also formative outcomes to assess the extent to which implementation is effective in a specific setting, prolongs sustainability, and promotes dissemination into other settings. Many implementation theories have been published to help promote effective implementation. However, they overlap considerably in the constructs included in individual theories, and a comparison of theories reveals that each is missing important constructs included in other theories. In addition, terminology and definitions are not consistent across theories. We describe the Consolidated Framework For Implementation Research (CFIR that offers an overarching typology to promote implementation theory development and verification about what works where and why across multiple contexts. Methods We used a snowball sampling approach to identify published theories that were evaluated to identify constructs based on strength of conceptual or empirical support for influence on implementation, consistency in definitions, alignment with our own findings, and potential for measurement. We combined constructs across published theories that had different labels but were redundant or overlapping in definition, and we parsed apart constructs that conflated underlying concepts. Results The CFIR is composed of five major domains: intervention characteristics, outer setting, inner setting, characteristics of the individuals involved, and the process of implementation. Eight constructs were identified related to the intervention (e.g., evidence strength and quality, four constructs were identified related to outer setting (e.g., patient needs and resources, 12 constructs were identified related to inner setting (e.g., culture

  15. Improving the Grade Point Average of Our At-Risk Students: A Collaborative Group Action Research Approach.

    Science.gov (United States)

    Saurino, Dan R.; Hinson, Kenneth; Bouma, Amy

    This paper focuses on the use of a group action research approach to help student teachers develop strategies to improve the grade point average of at-risk students. Teaching interventions such as group work and group and individual tutoring were compared to teaching strategies already used in the field. Results indicated an improvement in the…

  16. Death, cadavers and post-mortem biomedical research: a point of view from a Christian community.

    Science.gov (United States)

    Charlier, Philippe; Joly, Alain; Champagnat, Julie; Brun, Luc; de la Grandmaison, Geoffroy Lorin; Hervé, Christian

    2013-12-01

    Facing modern developments of medicine and biomedical researches, religious communities are a strong source of ethics principles and orientations. Human dignity does not disappear after life, in a context of biomedical research on cadavers. Moral, political, social and scientific aspects of research on human cadavers (mainly autopsies) have been widely discussed in biomedical publications, whereas the religious ones (which could be predominant for some) have rarely been analyzed and presented. This article will present the results of a survey carried out a French Benedictine Abbey (relative to death, cadaver's status and biomedical research) and subsequent Christian background according to canonic texts and practical cases from anthropological, historical, archeological and biomedical origin.

  17. Research cardiac magnetic resonance imaging in end stage renal disease - incidence, significance and implications of unexpected incidental findings

    Energy Technology Data Exchange (ETDEWEB)

    Rutherford, Elaine; Weir-McCall, Jonathan R.; Houston, J.G.; Struthers, Allan D. [Ninewells Hospital, Division of Cardiovascular and Diabetes Medicine, Dundee (United Kingdom); Patel, Rajan K.; Jardine, Alan G.; Mark, Patrick B. [Institute of Cardiovascular and Medical Sciences, Glasgow (United Kingdom); Roditi, Giles [NHS Greater Glasgow and Clyde, Department of Radiology, Glasgow Royal Infirmary, Glasgow (United Kingdom)

    2017-01-15

    Left ventricular mass (LVM) at cardiac magnetic resonance imaging (CMR) is a frequent end point in clinical trials in nephrology. Trial participants with end stage renal disease (ESRD) may have a greater frequency of incidental findings (IF). We retrospectively investigated prevalence of IF in previous research CMR and reviewed their subsequent impact on participants. Between 2002 and 2006, 161 ESRD patients underwent CMR in a transplant assessment study. Images were used to assess LV mass and function. In the current study a radiologist reviewed the scans for IF. Review of patient records determined the subsequent clinical significance of IF. There were 150 IF in 95 study participants. Eighty-four (56 %) were new diagnoses. One hundred and two were non-cardiac. Fifteen were suspicious of malignancy. There was a clinically significant IF for 14.9 % of the participants. In six cases earlier identification of an IF may have improved quality of life or survival. Without radiology support clinically important IF may be missed on CMR. Patients undergoing CMR in trials should be counselled about the frequency and implications of IF. Patients with ESRD have a higher prevalence of IF than reported in other populations. Nephrology studies require mechanisms for radiologist reporting and strategies for dealing with IF. (orig.)

  18. A Research on Fast Face Feature Points Detection on Smart Mobile Devices

    Directory of Open Access Journals (Sweden)

    Xiaohe Li

    2018-01-01

    Full Text Available We explore how to leverage the performance of face feature points detection on mobile terminals from 3 aspects. First, we optimize the models used in SDM algorithms via PCA and Spectrum Clustering. Second, we propose an evaluation criterion using Linear Discriminative Analysis to choose the best local feature descriptions which plays a critical role in feature points detection. Third, we take advantage of multicore architecture of mobile terminal and parallelize the optimized SDM algorithm to improve the efficiency further. The experiment observations show that our final accomplished GPC-SDM (improved Supervised Descent Method using spectrum clustering, PCA, and GPU acceleration suppresses the memory usage, which is beneficial and efficient to meet the real-time requirements.

  19. The Association between Point-of-Sale Advertising Bans and Youth Experimental Smoking: Findings from the Global Youth Tobacco Survey (GYTS

    Directory of Open Access Journals (Sweden)

    Ce Shang

    2015-12-01

    Full Text Available Background and Objectives: while existing research has demonstrated a positive association between exposure to point-of-sale (POS tobacco advertising and youth smoking, there is limited evidence on the relationship between POS advertising restrictions and experimental smoking among youth. This study aims to fill this research gap by analyzing the association between POS advertising bans and youths' experimental smoking. Methods: Global Youth Tobacco Surveys from 130 countries during 2007-2011 were linked to the WHO “MPOWER” tobacco control policy measures to analyze the association between POS advertising bans (a dichotomous measure of the existence of such bans and experimental smoking using weighted logistic regressions. All analyses were clustered at the country level and controlled for age, parents' smoking status, GDP per capita, and country-level tobacco control scores in monitoring tobacco use, protecting people from smoke, offering help to quit, warning about the dangers of tobacco, enforcing promotion/advertising bans, and raising taxes on tobacco. Results: The results suggest that a POS advertising ban is significantly associated with reduced experimental smoking among youth (OR = 0.63, p p p < 0.001. Conclusions: POS advertising bans are significantly associated with reduced experimental smoking among youth. Adopting POS advertising bans has the potential to reduce tobacco use among their youth in countries currently without such bans.

  20. The Association between Point-of-Sale Advertising Bans and Youth Experimental Smoking: Findings from the Global Youth Tobacco Survey (GYTS).

    Science.gov (United States)

    Shang, Ce; Huang, Jidong; Li, Qing; Chaloupka, Frank J

    while existing research has demonstrated a positive association between exposure to point-of-sale (POS) tobacco advertising and youth smoking, there is limited evidence on the relationship between POS advertising restrictions and experimental smoking among youth. This study aims to fill this research gap by analyzing the association between POS advertising bans and youths' experimental smoking. Global Youth Tobacco Surveys from 130 countries during 2007-2011 were linked to the WHO "MPOWER" tobacco control policy measures to analyze the association between POS advertising bans (a dichotomous measure of the existence of such bans) and experimental smoking using weighted logistic regressions. All analyses were clustered at the country level and controlled for age, parents' smoking status, GDP per capita, and country-level tobacco control scores in monitoring tobacco use, protecting people from smoke, offering help to quit, warning about the dangers of tobacco, enforcing promotion/advertising bans, and raising taxes on tobacco. The results suggest that a POS advertising ban is significantly associated with reduced experimental smoking among youth (OR = 0.63, p advertising bans are significantly associated with reduced experimental smoking among youth. Adopting POS advertising bans has the potential to reduce tobacco use among their youth in countries currently without such bans.

  1. Development of the pediatric daily ulcerative colitis signs and symptoms scale (DUCS): qualitative research findings.

    Science.gov (United States)

    Flood, Emuella; Silberg, Debra G; Romero, Beverly; Beusterien, Kathleen; Erder, M Haim; Cuffari, Carmen

    2017-09-25

    The purpose of this study is to develop patient-reported (PRO) and observer-reported (ObsRO) outcome measures of ulcerative colitis (UC) signs/symptoms in children aged 5-17 with mild/moderate UC. The daily ulcerative colitis signs and symptoms scale (DUCS) was developed in two phases. Phase I involved concept elicitation interviews with patients and healthcare providers, review of website posts and item generation. Phase II involved cognitive debriefing and assessment of usability and feasibility of the eDiaries. Participants were recruited from five US clinical sites, a research recruitment agency, and internet advertising. Thematic and content analysis was performed to identify concepts from Phase I. The Phase II cognitive debriefing interviews were analyzed iteratively to identify problems with clarity and relevance of eDiary content. The US Food and Drug Administration (FDA) also reviewed and provided feedback on the eDiaries. Phase I included 32 participants (22 remission; 10 active disease). Phase II included 38 participants (22 remission; 16 active disease). A core set of seven signs and symptoms emerged that were reported by at least 30% of the patients interviewed: abdominal pain, blood in stool, frequent stools, diarrhea, stool urgency, nighttime stools, and tiredness. Participant input influenced changes such as refinement of item wording, revision of graphics, and selection of response scales. Revisions suggested by FDA included simplifying the response scale and adding questions to capture symptoms during sleeping hours. The findings of instrument development suggest that the DUCS PRO and ObsRO eDiaries are content-valid instruments for capturing the daily signs and symptoms of pediatric patients with mild to moderate UC in a clinical trial setting.

  2. Finding, Serving, and Housing the Homeless: Using Collaborative Research to Prepare Social Work Students for Research and Practice

    Science.gov (United States)

    Lane, Shannon R.; McClendon, Jennifer; Matthews, Natalie

    2017-01-01

    Social work plays a key role in engaging with clients and communities directly affected by housing insecurity and homelessness, and advocating for the right to safe and affordable housing. This article describes methodologies of the Point-in-Time Count and Homeless Management Information Systems and proposes strategies for integrating additional…

  3. INDUSTRY-UNIVERSITY COLLABORATION FROM THE POINT OF VIEW OF COMPANIES AS RESEARCH CUSTOMERS

    DEFF Research Database (Denmark)

    Gerstlberger, Wolfgang; Kesting, Tobias

    With regard to the increasing competitive situation in many industries due to continuous globalisation, companies more and more have to take into account external research support in order to maintain or even improve their competitiveness. In order to gain new and more detailed insights...... provide the core for a proposed segmentation framework concept for universities as suppliers on research markets. Following this idea, combined with the theoretical framework of market segmentation and transferring the customer segmentation approach to research markets, our paper gives concrete managerial...... into the actual experiences and perceived benefits of companies cooperating with universities and other external research institutions concerning particularly innovation-related support like product or prototype development, we conducted a transnational empirical survey in 2009. It addressed companies from...

  4. Point of View: The Importance of Teaching Neuroscience Research at Historically Black Colleges and Universities

    Science.gov (United States)

    Cohen, Jeremy

    2016-01-01

    This column shares reflections or thoughtful opinions on issues of broad interest to the community. This month's issue discusses the importance of the insights that are gained through neuroscience research.

  5. Testicular germ cell tumors and related research from a historical point of view

    DEFF Research Database (Denmark)

    Damjanov, Ivan; Albrechtsen, Nicolai Jacob Wewer

    2013-01-01

    and histogenesis have been elucidated in part by contributions in the field of experimental pathology and developmental biology. Correlation between clinical oncologic findings, pathology and experimental studies of germ cell tumors and related topics ushered the era of cellular and genetic engineering that have...

  6. Incidental findings are frequent in young healthy individuals undergoing magnetic resonance imaging in brain research imaging studies

    DEFF Research Database (Denmark)

    Hartwigsen, Gesa; Siebner, Hartwig R; Deuschl, Günther

    2010-01-01

    There is an ongoing debate about how to handle incidental findings (IF) detected in healthy individuals who participate in research-driven magnetic resonance imaging (MRI) studies. There are currently no established guidelines regarding their management....

  7. All-sky-imaging capabilities for ionospheric space weather research using geomagnetic conjugate point observing sites

    Science.gov (United States)

    Martinis, C.; Baumgardner, J.; Wroten, J.; Mendillo, M.

    2018-04-01

    Optical signatures of ionospheric disturbances exist at all latitudes on Earth-the most well known case being visible aurora at high latitudes. Sub-visual emissions occur equatorward of the auroral zones that also indicate periods and locations of severe Space Weather effects. These fall into three magnetic latitude domains in each hemisphere: (1) sub-auroral latitudes ∼40-60°, (2) mid-latitudes (20-40°) and (3) equatorial-to-low latitudes (0-20°). Boston University has established a network of all-sky-imagers (ASIs) with sites at opposite ends of the same geomagnetic field lines in each hemisphere-called geomagnetic conjugate points. Our ASIs are autonomous instruments that operate in mini-observatories situated at four conjugate pairs in North and South America, plus one pair linking Europe and South Africa. In this paper, we describe instrument design, data-taking protocols, data transfer and archiving issues, image processing, science objectives and early results for each latitude domain. This unique capability addresses how a single source of disturbance is transformed into similar or different effects based on the unique "receptor" conditions (seasonal effects) found in each hemisphere. Applying optical conjugate point observations to Space Weather problems offers a new diagnostic approach for understanding the global system response functions operating in the Earth's upper atmosphere.

  8. 78 FR 23255 - Findings of Misconduct in Science/Research Misconduct

    Science.gov (United States)

    2013-04-18

    ... research misconduct in research funded by National Institute of General Medical Sciences (NIGMS), National... peptide, and by falsely inserting a band in lane 3 to represent the [alpha]VBS peptide, in Figure 4B of...

  9. Considerations and Future Research Directions for E-Cigarette Warnings?Findings from Expert Interviews

    OpenAIRE

    Wackowski, Olivia A.; Hammond, David; O?Connor, Richard J.; Strasser, Andrew A.; Delnevo, Cristine D.

    2017-01-01

    Tobacco warning labels are important sources of risk information but research historically has been cigarette-centric. This qualitative study aimed to inform future direction and research on warnings for e-cigarettes. Between June and August 2016, we conducted interviews with 10 researchers with expertise in tobacco warning label research. Interviewees were registrants of a 2016 National Cancer Institute grantee meeting on tobacco warnings. Several participants agreed that the Food and Drug A...

  10. Leading US nano-scientists’ perceptions about media coverage and the public communication of scientific research findings

    International Nuclear Information System (INIS)

    Corley, Elizabeth A.; Kim, Youngjae; Scheufele, Dietram A.

    2011-01-01

    Despite the significant increase in the use of nanotechnology in academic research and commercial products over the past decade, there have been few studies that have explored scientists’ perceptions and attitudes about the technology. In this article, we use survey data from the leading U.S. nano-scientists to explore their perceptions about two issues: the public communication of research findings and media coverage of nanotechnology, which serves as one relatively rapid outlet for public communication. We find that leading U.S. nano-scientists do see an important connection between the public communication of research findings and public attitudes about science. Also, there is a connection between the scientists’ perceptions about media coverage and their views on the timing of public communication; scientists with positive attitudes about the media are more likely to support immediate public communication of research findings, while others believe that communication should take place only after research findings have been published through a peer-review process. We also demonstrate that journalists might have a more challenging time getting scientists to talk with them about nanotechnology news stories because nano-scientists tend to view media coverage of nanotechnology as less credible and less accurate than general science media coverage. We conclude that leading U.S. nano-scientists do feel a sense of responsibility for communicating their research findings to the public, but attitudes about the timing and the pathway of that communication vary across the group.

  11. Leading US nano-scientists' perceptions about media coverage and the public communication of scientific research findings

    Science.gov (United States)

    Corley, Elizabeth A.; Kim, Youngjae; Scheufele, Dietram A.

    2011-12-01

    Despite the significant increase in the use of nanotechnology in academic research and commercial products over the past decade, there have been few studies that have explored scientists' perceptions and attitudes about the technology. In this article, we use survey data from the leading U.S. nano-scientists to explore their perceptions about two issues: the public communication of research findings and media coverage of nanotechnology, which serves as one relatively rapid outlet for public communication. We find that leading U.S. nano-scientists do see an important connection between the public communication of research findings and public attitudes about science. Also, there is a connection between the scientists' perceptions about media coverage and their views on the timing of public communication; scientists with positive attitudes about the media are more likely to support immediate public communication of research findings, while others believe that communication should take place only after research findings have been published through a peer-review process. We also demonstrate that journalists might have a more challenging time getting scientists to talk with them about nanotechnology news stories because nano-scientists tend to view media coverage of nanotechnology as less credible and less accurate than general science media coverage. We conclude that leading U.S. nano-scientists do feel a sense of responsibility for communicating their research findings to the public, but attitudes about the timing and the pathway of that communication vary across the group.

  12. The nuclear physician's point of view: positron emission tomography in research activities: how? why?

    International Nuclear Information System (INIS)

    Billotey, C.; Janier, M.

    2005-01-01

    Positron Emission Tomography (PET) constitutes a non-traumatic, dynamic and quantitative functional imaging method, particularly adapted for biological and medical investigations. Various topics can be investigated by PET, such as animal models of human pathologies, physiopathological processes, therapeutic and diagnostic strategies. The number and variety of questions for which PET can provide answers depends on the development and adaptation of tools offered by PET research centres and especially depends on the variety of available radiopharmaceutical agents. To answer researchers' questions, these centres should be equipped with dedicated and functional imaging platforms, as well as having a defined development policy. The objectives of this policy should be agreed by consensus by a multidisciplinary team under the leadership of medical and biological researchers. (author)

  13. Research on Scheduling Algorithm for Multi-satellite and Point Target Task on Swinging Mode

    Science.gov (United States)

    Wang, M.; Dai, G.; Peng, L.; Song, Z.; Chen, G.

    2012-12-01

    Nowadays, using satellite in space to observe ground is an important and major method to obtain ground information. With the development of the scientific technology in the field of space, many fields such as military and economic and other areas have more and more requirement of space technology because of the benefits of the satellite's widespread, timeliness and unlimited of area and country. And at the same time, because of the wide use of all kinds of satellites, sensors, repeater satellites and ground receiving stations, ground control system are now facing great challenge. Therefore, how to make the best value of satellite resources so as to make full use of them becomes an important problem of ground control system. Satellite scheduling is to distribute the resource to all tasks without conflict to obtain the scheduling result so as to complete as many tasks as possible to meet user's requirement under considering the condition of the requirement of satellites, sensors and ground receiving stations. Considering the size of the task, we can divide tasks into point task and area task. This paper only considers point targets. In this paper, a description of satellite scheduling problem and a chief introduction of the theory of satellite scheduling are firstly made. We also analyze the restriction of resource and task in scheduling satellites. The input and output flow of scheduling process are also chiefly described in the paper. On the basis of these analyses, we put forward a scheduling model named as multi-variable optimization model for multi-satellite and point target task on swinging mode. In the multi-variable optimization model, the scheduling problem is transformed the parametric optimization problem. The parameter we wish to optimize is the swinging angle of every time-window. In the view of the efficiency and accuracy, some important problems relating the satellite scheduling such as the angle relation between satellites and ground targets, positive

  14. Behavioral and Social Sciences at the National Institutes of Health: adoption of research findings in health research and practice as a scientific priority.

    Science.gov (United States)

    Riley, William T

    2017-06-01

    The National Institutes of Health's Office of Behavioral and Social Sciences Research (OBSSR) recently released its Strategic Plan for 2017 to 2021. This plan highlights three scientific priorities: (1) improve the synergy of basic and applied behavioral and social sciences research, (2) enhance and promote the research infrastructure, methods, and measures needed to support a more cumulative and integrated approach to behavioral and social sciences research, and (3) facilitate the adoption of behavioral and social sciences research findings in health research and in practice. This commentary focuses on the challenges and opportunities to facilitate the adoption of research findings in health research and in practice. In addition to the ongoing NIH support for dissemination and implementation (D&I) research, we must address transformative challenges and opportunities such as better disseminating and implementing D&I research, merging research and practice, adopting more rigorous and diverse methods and measures for both D&I and clinical trials research, evaluating technological-based delivery of interventions, and transitioning from minimally adaptable intervention packages to planned adaptations rooted in behavior change principles. Beyond translation into practice and policy, the OBSSR Strategic Plan also highlights the need for translation of behavioral and social science findings into the broader biomedical research enterprise.

  15. WEBER‘S “SPIRIT OF CAPITALISM“ THESIS AS A STARTING POINT FOR FINDING SPIRITUAL POTENTIALS IN BUSINESS AND MANAGEMENT ENVIRONMENT

    Directory of Open Access Journals (Sweden)

    Kučera Dušan

    2015-12-01

    Full Text Available The study is focused on identification of spiritual factors in entrepreneurship and management. The author uses Weber’s thesis as a starting point for the processing of general spiritual concepts which have a major impact on the emergence, development and maintenance of the economic environment, business and management. The clarification of a fundamental understanding of the phenomenon of spirituality is followed by a description of spiritual factors in entrepreneurial and managerial activities looking for a  “new spirit of capitalism” today. The practical part is devoted to provision of a proof of spiritual influences on business and economic developments in the world (selection of studies. The work culminates in original research into positive and negative spiritual factors and potentials of entrepreneurship and management among selected entrepreneurs and managers in the Czech Republic. The collected factors and potentials are summarised, evaluated and proposed for use in entrepreneurial and managerial practice or as an impulse for managerial training.

  16. Turning Points in Qualitative Research: Tying Knots in a Handkerchief. Crossroads in Qualitative Inquiry Series.

    Science.gov (United States)

    Lincoln, Yvonna S., Ed.; Denzin, Norman K., Ed.

    The chapters of this volume traces the changes in the discipline of qualitative inquiry over the last five decades. The collection serves as a textbook for training scholars in the history and trajectory of qualitative research. The chapters of part 1, The Revolution of Representation: Feminist and Race/Ethnic Studies Discourses, are: (1) Situated…

  17. Assessment of Landscape Changes: Theoretical Starting Points for Study and the Research Reality

    Czech Academy of Sciences Publication Activity Database

    Kolejka, Jaromír; Trnka, P.

    2008-01-01

    Roč. 16, č. 3 (2008), s. 2-15 ISSN 1210-8812 Institutional research plan: CEZ:AV0Z30860518 Keywords : criteria of landscape changes * landscape structures * space- time - dynamics Subject RIV: DE - Earth Magnetism, Geodesy, Geography

  18. Why Understanding Science Matters: The IES Research Guidelines as a Case in Point

    Science.gov (United States)

    Rudolph, John L.

    2014-01-01

    The author outlines the rise of a hard-science model advocated by the Institute for Education Sciences, including the application of research and development approaches to education following the Second World War, and describes the attraction of these hard-science approaches for education policymakers. He notes that in the face of complex and…

  19. Barriers to Point-of-Care Testing in India: Results from Qualitative Research across Different Settings, Users and Major Diseases

    Science.gov (United States)

    Engel, Nora; Ganesh, Gayatri; Patil, Mamata; Yellappa, Vijayashree; Pant Pai, Nitika; Vadnais, Caroline; Pai, Madhukar

    2015-01-01

    Background Successful point-of-care testing, namely ensuring the completion of the test and treat cycle in the same encounter, has immense potential to reduce diagnostic and treatment delays, and impact patient outcomes. However, having rapid tests is not enough, as many barriers may prevent their successful implementation in point-of-care testing programs. Qualitative research on diagnostic practices may help identify such barriers across different points of care in health systems. Methods In this exploratory qualitative study, we conducted 78 semi-structured interviews and 13 focus group discussions in an urban and rural area of Karnataka, India, with healthcare providers (doctors, nurses, specialists, traditional healers, and informal providers), patients, community health workers, test manufacturers, laboratory technicians, program managers and policy-makers. Participants were purposively sampled to represent settings of hospitals, peripheral labs, clinics, communities and homes, in both the public and private sectors. Results In the Indian context, the onus is on the patient to ensure successful point-of-care testing across homes, clinics, labs and hospitals, amidst uncoordinated providers with divergent and often competing practices, in settings lacking material, money and human resources. We identified three overarching themes affecting point-of-care testing: the main theme is ‘relationships’ among providers and between providers and patients, influenced by the cross-cutting theme of ‘infrastructure’. Challenges with both result in ‘modified practices’ often favouring empirical (symptomatic) treatment over treatment guided by testing. Conclusions Even if tests can be conducted on the spot and infrastructure challenges have been resolved, relationships among providers and between patients and providers are crucial for successful point-of-care testing. Furthermore, these barriers do not act in isolation, but are interlinked and need to be examined

  20. Barriers to Point-of-Care Testing in India: Results from Qualitative Research across Different Settings, Users and Major Diseases.

    Directory of Open Access Journals (Sweden)

    Nora Engel

    Full Text Available Successful point-of-care testing, namely ensuring the completion of the test and treat cycle in the same encounter, has immense potential to reduce diagnostic and treatment delays, and impact patient outcomes. However, having rapid tests is not enough, as many barriers may prevent their successful implementation in point-of-care testing programs. Qualitative research on diagnostic practices may help identify such barriers across different points of care in health systems.In this exploratory qualitative study, we conducted 78 semi-structured interviews and 13 focus group discussions in an urban and rural area of Karnataka, India, with healthcare providers (doctors, nurses, specialists, traditional healers, and informal providers, patients, community health workers, test manufacturers, laboratory technicians, program managers and policy-makers. Participants were purposively sampled to represent settings of hospitals, peripheral labs, clinics, communities and homes, in both the public and private sectors.In the Indian context, the onus is on the patient to ensure successful point-of-care testing across homes, clinics, labs and hospitals, amidst uncoordinated providers with divergent and often competing practices, in settings lacking material, money and human resources. We identified three overarching themes affecting point-of-care testing: the main theme is 'relationships' among providers and between providers and patients, influenced by the cross-cutting theme of 'infrastructure'. Challenges with both result in 'modified practices' often favouring empirical (symptomatic treatment over treatment guided by testing.Even if tests can be conducted on the spot and infrastructure challenges have been resolved, relationships among providers and between patients and providers are crucial for successful point-of-care testing. Furthermore, these barriers do not act in isolation, but are interlinked and need to be examined as such. Also, a test alone has only

  1. [Taking evaluation of post-marketing as point of cut-in to promote systematic research of traditional Chinese medicine].

    Science.gov (United States)

    Wang, Yong-yan; Wang, Zhi-fei; Xie, Yan-ming

    2014-09-01

    Research on post-marketing Chinese medicine should be the systematic study from application to mechanism. Clinical evaluation is the basis of mechanism study, we can find the clue from clinical evaluation, then make a mechanism study to find the reason, then apply the results to clinic. So it is a virtuous circle. In order to achieve it, we cannot be limited to traditional Chinese medicine, we should form multi-disciplinary team under the direction of grand science thinking, try hard to put industry-university-research institute collaboration association to use, and if necessary, explore the new model of the whole nation system. An appropriate operation mechanism is very important.

  2. Development and Pilot Testing of a Decision Aid for Genomic Research Participants Notified of Clinically Actionable Research Findings for Cancer Risk.

    Science.gov (United States)

    Willis, Amanda M; Smith, Sian K; Meiser, Bettina; Ballinger, Mandy L; Thomas, David M; Tattersall, Martin; Young, Mary-Anne

    2018-02-17

    Germline genomic testing is increasingly used in research to identify genetic causes of disease, including cancer. However, there is evidence that individuals who are notified of clinically actionable research findings have difficulty making informed decisions regarding uptake of genetic counseling for these findings. This study aimed to produce and pilot test a decision aid to assist participants in genomic research studies who are notified of clinically actionable research findings to make informed choices regarding uptake of genetic counseling. Development was guided by published literature, the International Patient Decision Aid Standards, and the expertise of a steering committee of clinicians, researchers, and consumers. Decision aid acceptability was assessed by self-report questionnaire. All 19 participants stated that the decision aid was easy to read, clearly presented, increased their understanding of the implications of taking up research findings, and would be helpful in decision-making. While low to moderate levels of distress/worry were reported after reading the booklet, a majority of participants also reported feeling reassured. All participants would recommend the booklet to others considering uptake of clinically actionable research findings. Results indicate the decision aid is acceptable to the target audience, with potential as a useful decision support tool for genomic research participants.

  3. Impact of mesh points number on the accuracy of deterministic calculations of control rods worth for Tehran research reactor

    International Nuclear Information System (INIS)

    Boustani, Ehsan; Amirkabir University of Technology, Tehran; Khakshournia, Samad

    2016-01-01

    In this paper two different computational approaches, a deterministic and a stochastic one, were used for calculation of the control rods worth of the Tehran research reactor. For the deterministic approach the MTRPC package composed of the WIMS code and diffusion code CITVAP was used, while for the stochastic one the Monte Carlo code MCNPX was applied. On comparing our results obtained by the Monte Carlo approach and those previously reported in the Safety Analysis Report (SAR) of Tehran research reactor produced by the deterministic approach large discrepancies were seen. To uncover the root cause of these discrepancies, some efforts were made and finally was discerned that the number of spatial mesh points in the deterministic approach was the critical cause of these discrepancies. Therefore, the mesh optimization was performed for different regions of the core such that the results of deterministic approach based on the optimized mesh points have a good agreement with those obtained by the Monte Carlo approach.

  4. Impact of mesh points number on the accuracy of deterministic calculations of control rods worth for Tehran research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Boustani, Ehsan [Nuclear Science and Technology Research Institute (NSTRI), Tehran (Iran, Islamic Republic of); Amirkabir University of Technology, Tehran (Iran, Islamic Republic of). Energy Engineering and Physics Dept.; Khakshournia, Samad [Amirkabir University of Technology, Tehran (Iran, Islamic Republic of). Energy Engineering and Physics Dept.

    2016-12-15

    In this paper two different computational approaches, a deterministic and a stochastic one, were used for calculation of the control rods worth of the Tehran research reactor. For the deterministic approach the MTRPC package composed of the WIMS code and diffusion code CITVAP was used, while for the stochastic one the Monte Carlo code MCNPX was applied. On comparing our results obtained by the Monte Carlo approach and those previously reported in the Safety Analysis Report (SAR) of Tehran research reactor produced by the deterministic approach large discrepancies were seen. To uncover the root cause of these discrepancies, some efforts were made and finally was discerned that the number of spatial mesh points in the deterministic approach was the critical cause of these discrepancies. Therefore, the mesh optimization was performed for different regions of the core such that the results of deterministic approach based on the optimized mesh points have a good agreement with those obtained by the Monte Carlo approach.

  5. Achievements, Challenges, and Opportunities in DNA-Encoded Library Research: An Academic Point of View.

    Science.gov (United States)

    Yuen, Lik Hang; Franzini, Raphael M

    2017-05-04

    DNA-encoded chemical libraries (DECLs) are pools of DNA-tagged small molecules that enable facile screening and identification of bio-macromolecule binders. The successful development of DECLs has led to their increasingly important role in drug development, and screening hits have entered clinical trials. In this review, we summarize the development and currently active research areas of DECLs with a focus on contributions from groups at academic institutes. We further look at opportunities and future directions of DECL research in medicinal chemistry and chemical biology based on the symbiotic relationship between academia and industry. Challenges associated with the application of DECLs in academic drug discovery are further discussed. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Improving Hawaiian and Filipino involvement in clinical research opportunities: qualitative findings from Hawai'i.

    Science.gov (United States)

    Gollin, Lisa X; Harrigan, Rosanne C; Calderón, José L; Perez, John; Easa, David

    2005-01-01

    Investigate the barriers to participation in medical research that involves Asian and Pacific Islander (API) populations in Hawai'i. Fifty people (27 Filipinos, 23 Hawaiian/Pacific Islanders) in five different communities on Oahu. Nine focus groups with an ethnically matched moderator were held to explore people's feelings, problems, and recommendations regarding medical research. Sessions were audiotaped, transcribed, and qualitatively analyzed with the constant comparison method. Only 12% of study participants said that they absolutely would not participate in a clinical study. Most agreed that research is vital. Filipino participants were more optimistic about the safety and value of joining in medical research. Hawaiian groups were more hesitant and fearful. Reasons for nonparticipation included negative feelings about the purpose and intent of clinical trials and language and cultural barriers. Suggestions on how to encourage API populations to participate in research investigations included improving peoples' understanding of the benefits to family and community. Hawaiian and Filipino groups differed only slightly in their assessments of the type of research needed in their communities. Recruitment campaigns must improve people's awareness of the process of informed consent, research safeguards, and benefits to family and community. Attention should focus on K-12 health education to use members of the younger generations to access and educate elders, involving persons with medical research experience as a recruitment resource, returning results to study participants, and increasing the number of healthcare professionals and researchers that are culturally and linguistically matched to the community.

  7. An analysis of market development strategy of a point-of-sale solutions provider's market research database

    OpenAIRE

    Medina, Ahmed

    2007-01-01

    This paper is a strategic analysis of Vivonet Inc. and its restaurant performance-benchmarking tool ZATA. Vivonet is a Point of Sales (POS) systems provider for the hospitality and the retail industry. Its ZATA product captures POS and other related information from restaurants and allows the restaurants to compare their performance with restaurants in their market segment. With ZATA, Vivonet has the opportunity to extend beyond the POS systems segment and compete in the market research i...

  8. Applications of Operational Research Techniques in Optimization to Visit Tourist Points of Vina del Mar

    Directory of Open Access Journals (Sweden)

    Joao CARDOSO NETO

    2012-01-01

    Full Text Available Chile is a country with great attractions for tourists in South America and the whole world. Among the many tourist Chilean attractions the city of Vina del Mar is one of the highlights, recognized nationally and internationally as one of the most beautiful places for summer. In Vina del Mar tourists have many options for leisure, besides pretty beaches, e.g. playa renaca, the city has beautiful squares and castles, e.g. Castillo Wulff built more than 100 (one hundred years ago. It is noteworthy that already exist over there five (5 tourist itineraries, so this work was developed in order to determine the best routes to these existing itineraries, and create a unique route that includes all the tourist points in Vina del Mar, because in this way, the tourists visiting this city can minimize the time spent in traveling, as well as optimize their moments of leisure, taking the opportunity to know all the city attractions. To determine shorter ways to do it and then propose some suggestions for improvement of the quality of the tourist service offered, it had used the exact method, by solving the mathematical model of the TSP (Traveling Salesman Problem, and the heuristic method, using the most economic insertion algorithm.

  9. Towards Understanding EFL Teachers' Conceptions of Research: Findings from Argentina

    Science.gov (United States)

    Banegas, Darío Luis

    2018-01-01

    This paper investigates the conceptions of research held by English as a foreign language teachers in Argentina. Quantitative data from 622 participants from an online questionnaire were followed by qualitative data from online interviews with 40 of those participants. Results show that the teachers conceptualised research through conventional…

  10. Research for Safe and Pin-point Lunar Landing and Exploration

    OpenAIRE

    松本, 甲太郎; MATSUMOTO, Kohtaro; 佐々, 修一; SASA, Shuichi; 若林, 幸子; WAKABAYASHI, Sachiko; 片山, 保宏; KATAYAMA, Yasuhiro; 二宮, 哲次郎; NINOMIYA, Tetsujiro; 濱田, 吉郎; HAMADA, Yoshiro; 藤原, 健; FUJIWARA, Takeshi

    2003-01-01

    The moon is widely regarded as the next step into space for us. NASA, ESA and other agencies have recently begun new missions in the next thrust towards lunar exploration. NAL has started fundamental studies of the technologies needed for the long-term utilization of the moon as a technological and scientific base. NAL is currently taking part in the research phase of the Selenological and Engineering Explorer - B (SELENE-B) project, which was separated from SELENE in 2000, and in 2001 was de...

  11. Research of HCR Gearing Properties from Warm Scuffing Damage Point of View

    Directory of Open Access Journals (Sweden)

    Kuzmanović Siniša

    2014-12-01

    Full Text Available The issue of design and dimensioning of HCR gearing, particularly of the gearings with an internal engagement, it nowadays, especially in the design of hybrid cars drives, highly topical. This kind of gearing has many advantages in operation, but at the same time it is more complicated in stage of its design and load capacity calculation. Authors in this contribution present some results of temperature scuffing research of internal and external HCR gearing. There are given the equations for calculation of warm scuffing resistance of both external and internal HCR gearing derived according to the integral temperature criterion.

  12. Modularity in automakers: a research under the strategy point of view

    Directory of Open Access Journals (Sweden)

    José Antonio Carnevalli

    2015-06-01

    Full Text Available The relationships between the application of modularity in the car industry and the organizational strategies are a study field which needs to be better understood. This study is intended to research the organizational strategies and competencies inherent to the modularity process in the car-making enterprises. Case-based research was conducted in two car-makers. The study shows that the modularity process has been used to transfer fixed costs to the suppliers generating dependence among the enterprises and making the change of supplier difficult whenever necessary. There is concern of the car-makers in creating strategies capable of preventing the loss of know how. For this reason, not all the projects of the modules are outsourced. It was found that the enterprises studied reached partially the essential competencies and operate at the level of the distinctive competencies, but enough to give support to modular strategy. The set of organizational strategies and competencies conquered held in the construction of competitive advantage in those enterprises.

  13. Considerations and Future Research Directions for E-Cigarette Warnings—Findings from Expert Interviews

    Science.gov (United States)

    Wackowski, Olivia A.; Hammond, David; O’Connor, Richard J.; Strasser, Andrew A.; Delnevo, Cristine D.

    2017-01-01

    Tobacco warning labels are important sources of risk information but research historically has been cigarette-centric. This qualitative study aimed to inform future direction and research on warnings for e-cigarettes. Between June and August 2016, we conducted interviews with 10 researchers with expertise in tobacco warning label research. Interviewees were registrants of a 2016 National Cancer Institute grantee meeting on tobacco warnings. Several participants agreed that the Food and Drug Administration’s new nicotine addiction warning for e-cigarettes could be informative but that it might not resonate with young people. Many agreed that more than one warning would be important as e-cigarette science evolves and that research on additional warning themes (e.g., nicotine exposure, harmful constituents) and execution styles (including use of pictorials) was important. Participants were somewhat mixed about the use of reduced-risk messages within e-cigarette warnings, but agreed that research on how to communicate about cigarette/e-cigarette relative risks was needed. Overall, more research is needed on tobacco warnings for non-cigarette products, including on the message content, placement, execution and potential impact on audiences’ product knowledge, risk perceptions and use intentions. This is particularly needed for products such as e-cigarettes which may have harm-reduction potential relative to cigarettes and require unique considerations. PMID:28708124

  14. Considerations and Future Research Directions for E-Cigarette Warnings-Findings from Expert Interviews.

    Science.gov (United States)

    Wackowski, Olivia A; Hammond, David; O'Connor, Richard J; Strasser, Andrew A; Delnevo, Cristine D

    2017-07-14

    Tobacco warning labels are important sources of risk information but research historically has been cigarette-centric. This qualitative study aimed to inform future direction and research on warnings for e-cigarettes. Between June and August 2016, we conducted interviews with 10 researchers with expertise in tobacco warning label research. Interviewees were registrants of a 2016 National Cancer Institute grantee meeting on tobacco warnings. Several participants agreed that the Food and Drug Administration's new nicotine addiction warning for e-cigarettes could be informative but that it might not resonate with young people. Many agreed that more than one warning would be important as e-cigarette science evolves and that research on additional warning themes (e.g., nicotine exposure, harmful constituents) and execution styles (including use of pictorials) was important. Participants were somewhat mixed about the use of reduced-risk messages within e-cigarette warnings, but agreed that research on how to communicate about cigarette/e-cigarette relative risks was needed. Overall, more research is needed on tobacco warnings for non-cigarette products, including on the message content, placement, execution and potential impact on audiences' product knowledge, risk perceptions and use intentions. This is particularly needed for products such as e-cigarettes which may have harm-reduction potential relative to cigarettes and require unique considerations.

  15. Women finding the way: American Indian women leading intervention research in Native communities.

    Science.gov (United States)

    Brave Heart, Maria Yellow Horse; Chase, Josephine; Elkins, Jennifer; Martin, Jennifer; Nanez, Jennifer; Mootz, Jennifer

    2016-01-01

    Although there is literature concentrating on cross-cultural approaches to academic and community partnerships with Native communities, few address the process and experiences of American Indian women leading federally funded and culturally grounded behavioral health intervention research in Native communities. This paper summarizes relevant literature on community-engaged research with Native communities, examines traditional roles and modern challenges for American Indian women, describes the culturally grounded collaborative process for the authors' behavioral health intervention development with Native communities, and considers emergent themes from our own research experiences navigating competing demands from mainstream and Native communities. It concludes with recommendations for supporting and enhancing resilience.

  16. Analysis and research on Maximum Power Point Tracking of Photovoltaic Array with Fuzzy Logic Control and Three-point Weight Comparison Method

    Institute of Scientific and Technical Information of China (English)

    LIN; Kuang-Jang; LIN; Chii-Ruey

    2010-01-01

    The Photovoltaic Array has a best optimal operating point where the array operating can obtain the maximum power.However, the optimal operating point can be compromised by the strength of solar radiation,angle,and by the change of environment and load.Due to the constant changes in these conditions,it has become very difficult to locate the optimal operating point by following a mathematical model.Therefore,this study will focus mostly on the application of Fuzzy Logic Control theory and Three-point Weight Comparison Method in effort to locate the optimal operating point of solar panel and achieve maximum efficiency in power generation. The Three-point Weight Comparison Method is the comparison between the characteristic curves of the voltage of photovoltaic array and output power;it is a rather simple way to track the maximum power.The Fuzzy Logic Control,on the other hand,can be used to solve problems that cannot be effectively dealt with by calculation rules,such as concepts,contemplation, deductive reasoning,and identification.Therefore,this paper uses these two kinds of methods to make simulation successively. The simulation results show that,the Three-point Comparison Method is more effective under the environment with more frequent change of solar radiation;however,the Fuzzy Logic Control has better tacking efficiency under the environment with violent change of solar radiation.

  17. Where to find weather and climatic data for forest research studies and management planning.

    Science.gov (United States)

    Donald A. Haines

    1977-01-01

    Forest-range research or operational study designs should include the possible effects of weather and climate. This document describes the meteorological observational networks, the data available from them, and where the information is stored.

  18. The North American long-term soil productivity experiment: findings from the first decade of research

    Science.gov (United States)

    Robert F. Powers; D. Andrew Scott; Felipe g. Sanchez; Richard A. Voldseth; Deborah Page-Dumroese; John D. Elioff; Douglas M. Stone

    2005-01-01

    First decade findings on the impacts of organic matter removal and soil compaction are reported for the 26 oldest installations in the nation-wide network of long-term soil productivity sites. Complete removal of surface organic matter led to declines in soil C concentration to 20 cm depth and to reduced nutrient availability. The effect is attributed mainly to the...

  19. Partnership for Equity in Education through Research (PEER): Findings from the First Year of Research on AANAPISIs

    Science.gov (United States)

    National Commission on Asian American and Pacific Islander Research in Education, 2013

    2013-01-01

    Through generous support from the Kresge Foundation, Lumina Foundation, USA Funds, and Walmart Foundation, the National Commission on Asian American and Pacific Islander Research on Education (CARE) teamed up with the Asian & Pacific Islander American Scholarship Fund (APIASF) and three AANAPISI campus partners--City College of San Francisco,…

  20. Steps to strengthen ethics in organizations: research findings, ethics placebos, and what works.

    Science.gov (United States)

    Pope, Kenneth S

    2015-01-01

    Research shows that many organizations overlook needs and opportunities to strengthen ethics. Barriers can make it hard to see the need for stronger ethics and even harder to take effective action. These barriers include the organization's misleading use of language, misuse of an ethics code, culture of silence, strategies of justification, institutional betrayal, and ethical fallacies. Ethics placebos tend to take the place of steps to see, solve, and prevent problems. This article reviews relevant research and specific steps that create change.

  1. Analysing Personal Characteristics of Lone-Actor Terrorists: Research Findings and Recommendations

    OpenAIRE

    Roy, de, van Zuijdewijn J.; Bakker, E.

    2016-01-01

    This Research Note presents the outcome of a project that looked at the personal characteristics of lone-actor terrorists. It is part of the larger Countering Lone-Actor Terrorism (CLAT) project. The project described here aimed to improve understanding of, and responses to, the phenomenon of (potentially) violent lone-actors based on an analysis of 120 cases from across Europe. The Research Note focuses on the personal characteristics of lone-actor terrorists.[1] First of all, it presents th...

  2. Cyberbullying Victimization and Behaviors Among Girls: Applying Research Findings in the Field

    OpenAIRE

    Patricia A. Snell; Elizabeth K. Englander

    2010-01-01

    Problem statement: Prior research on cyberbullying has been conducted; however specific research on gender differences has yet to be examined. The current study focuses on gender trends, specifically females, in cyberbullying victimization and behaviors. Approach: A survey was given to undergraduate students at Bridgewater State College in an effort to see what gender trends exist in cyberbullying behaviors. A pilot program focused on girls and cyberbullying is also examined in this article. ...

  3. Exploring the role of the nurse manager in supporting point-of-care nurses' adoption of electronic health records: protocol for a qualitative research study.

    Science.gov (United States)

    Strudwick, Gillian; Booth, Richard G; Bjarnadottir, Ragnhildur I; Collins, Sarah; Srivastava, Rani

    2017-10-12

    An increasing number of electronic health record (EHR) systems have been implemented in clinical practice environments where nurses work. Findings from previous studies have found that a number of intended benefits of the technology have not yet been realised to date, partially due to poor system adoption among health professionals such as nurses. Previous studies have suggested that nurse managers can support the effective adoption and use of the technology by nurses. However, no known studies have identified what role nurse managers have in supporting technology adoption, nor the specific strategies that managers can employ to support their staff. Therefore, the purpose of this research is to better understand the role of the nurse manager in point-of-care nurses' use of EHRs, and to identify strategies that may be effective in supporting clinical adoption. This study will use a qualitative descriptive design. Interviews with both nurse managers and point-of-care nursing staff will be conducted in a Canadian mental health and addiction healthcare organisation where an EHR has been implemented. A semistructured interview guide will be used, and interviews will be audio recorded. Transcripts will be analysed using a directed content analysis technique. Strategies to ensure the trustworthiness of the data analysis procedure and findings will be employed. Ethical approval for this study has been obtained. Dissemination strategies may include a paper submission to a peer-reviewed journal, a conference submission and meetings to share findings with the study site leadership team. Findings from this research will be used to inform a future study which aims to assess levels of competencies and perform a psychometric analysis of the Nursing Informatics Competency Assessment for the Nurse Leader instrument in a Canadian context. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is

  4. Strategies for Enhancing Family Participation in Research in the ICU: Findings From a Qualitative Study.

    Science.gov (United States)

    Dotolo, Danae; Nielsen, Elizabeth L; Curtis, J Randall; Engelberg, Ruth A

    2017-08-01

    Family members of critically ill patients who participate in research focused on palliative care issues have been found to be systematically different from those who do not. These differences threaten the validity of research and raise ethical questions about worsening disparities in care by failing to represent diverse perspectives. This study's aims were to explore: 1) barriers and facilitators influencing family members' decisions to participate in palliative care research; and 2) potential methods to enhance research participation. Family members who were asked to participate in a randomized trial testing the efficacy of a facilitator to improve clinician-family communication in the intensive care unit (ICU). Family members who participated (n = 17) and those who declined participation (n = 7) in Family Communication Study were interviewed about their recruitment experiences. We also included family members of currently critically ill patients to assess current experiences (n = 4). Interviews were audio-recorded and transcribed. Investigators used thematic analysis to identify factors influencing family members' decisions. Transcripts were co-reviewed to synthesize codes and themes. Three factors influencing participants' decisions were identified: Altruism, Research Experience, and Enhanced Resources. Altruism and Research Experience described intrinsic characteristics that are less amenable to strategies for improving participation rates. Enhanced Resources reflects families' desires for increased access to information and logistical and emotional support. Family members found their recruitment experiences to be positive when staff were knowledgeable about the ICU, sensitive to the stressful circumstances, and conveyed a caring attitude. By training research staff to be supportive of families' emotional needs and need for logistical knowledge about the ICU, recruitment of a potentially more diverse sample of families may be enhanced. Copyright © 2017

  5. Barriers to participation in mental health research: findings from the Genetics and Psychosis (GAP) Study.

    Science.gov (United States)

    Woodall, Anna; Howard, Louise; Morgan, Craig

    2011-01-01

    The aim of this study was to investigate why people with a first episode of psychosis choose or decline to participate in mental health research, using a qualitative study design. Participants were recruited via referrals from the Genetics and Psychosis (GAP) study. A total of 26 individuals with a first-episode of psychosis (nine of whom declined participation in the GAP study and 17 who participated) were individually interviewed and asked about their attitudes towards mental health research participation. Thematic analysis of interview transcripts was used to determine dominant themes and sub-themes on what constituted barriers and facilitators to participation. Reasons for research participation identified included a desire to help others, curiosity, and positive experiences with clinicians. Decisions to participate or not were also influenced by practical issues, including the timing of the approach, researchers' communication skills and whether individuals had concerns that it may be potentially harmful to their health. Other barriers to participation included patients' conceptualizations of mental health problems and the influence of other inpatients. Information on barriers and facilitators to recruitment in mental health research could inform recruitment strategies, thereby maximizing recruitment rates and minimizing the risk of selection biases.

  6. A Starting Point for Fluorescence-Based Single-Molecule Measurements in Biomolecular Research

    Directory of Open Access Journals (Sweden)

    Alexander Gust

    2014-09-01

    Full Text Available Single-molecule fluorescence techniques are ideally suited to provide information about the structure-function-dynamics relationship of a biomolecule as static and dynamic heterogeneity can be easily detected. However, what type of single-molecule fluorescence technique is suited for which kind of biological question and what are the obstacles on the way to a successful single-molecule microscopy experiment? In this review, we provide practical insights into fluorescence-based single-molecule experiments aiming for scientists who wish to take their experiments to the single-molecule level. We especially focus on fluorescence resonance energy transfer (FRET experiments as these are a widely employed tool for the investigation of biomolecular mechanisms. We will guide the reader through the most critical steps that determine the success and quality of diffusion-based confocal and immobilization-based total internal reflection fluorescence microscopy. We discuss the specific chemical and photophysical requirements that make fluorescent dyes suitable for single-molecule fluorescence experiments. Most importantly, we review recently emerged photoprotection systems as well as passivation and immobilization strategies that enable the observation of fluorescently labeled molecules under biocompatible conditions. Moreover, we discuss how the optical single-molecule toolkit has been extended in recent years to capture the physiological complexity of a cell making it even more relevant for biological research.

  7. Main points of research in crude oil processing and petrochemistry. [German Democratic Republic

    Energy Technology Data Exchange (ETDEWEB)

    Keil, G.; Nowak, S.; Fiedrich, G.; Klare, H.; Apelt, E.

    1982-04-01

    This article analyzes general aspects in the development of petrochemistry and carbochemistry on a global scale and for industry in the German Democratic Republic. Diagrams are given for liquid and solid carbon resources and their natural hydrogen content showing the increasing hydrogen demand for chemical fuel conversion processes. The petrochemical and carbochemical industry must take a growing level of hydrogen demand into account, which is at present 25 Mt/a on a global scale and which increases by 7% annually. Various methods for chemical processing of crude oil and crude oil residues are outlined. Advanced coal conversion processes with prospects for future application in the GDR are also explained, including the methanol carbonylation process, which achieves 90% selectivity and which is based on carbon monoxide hydrogenation, further the Transcat process, using ethane for vinyl chloride production. Acetylene and carbide carbochemistry in the GDR is a further major line in research and development. Technological processes for the pyrolysis of vacuum gas oil are also evaluated. (27 refs.)

  8. Insomnia in places of detention: a review of the most recent research findings

    OpenAIRE

    Elger, Bernice Simone

    2007-01-01

    Up to 40% of prisoner patients in a general medicine outpatient service seek medical consultation for sleep problems. This paper provides a brief overview of what is known about insomnia and its treatment from studies on non-detained patients and discusses the relevance of the findings from studies in liberty for prison health care. The clinical and ethical issues of insomnia in prison are described, followed by a summary of the existing studies on insomnia in prison. The results of the repor...

  9. Domestic Violence Between Same-Gender Partners: Recent Findings and Future Research

    Science.gov (United States)

    McClennen, Joan C.

    2005-01-01

    Empirical literature about same-gender domestic violence was relatively nonexistent until the past 20 years, and conducting research with this population about a sensitive topic remains a daunting endeavor. Existing studies reveal similarities between opposite- and same-gender domestic violence in prevalence, types of abuse, and various dynamics,…

  10. Informing Intervention Strategies to Reduce Energy Drink Consumption in Young People: Findings From Qualitative Research.

    Science.gov (United States)

    Francis, Jacinta; Martin, Karen; Costa, Beth; Christian, Hayley; Kaur, Simmi; Harray, Amelia; Barblett, Ann; Oddy, Wendy Hazel; Ambrosini, Gina; Allen, Karina; Trapp, Gina

    2017-10-01

    To determine young people's knowledge of energy drinks (EDs), factors influencing ED consumption, and intervention strategies to decrease ED consumption in young people. Eight group interviews with young people (aged 12-25 years). Community groups and secondary schools in Perth, Western Australia. Forty-one young people, 41% of whom were male and 73% of whom consumed EDs. Factors influencing ED consumption and intervention strategies informed by young people to reduce ED consumption. Two researchers conducted a qualitative content analysis on the data using NVivo software. Facilitators of ED consumption included enhanced energy, pleasant taste, low cost, peer pressure, easy availability, and ED promotions. Barriers included negative health effects, unpleasant taste, high cost, and parents' disapproval. Strategies to reduce ED consumption included ED restrictions, changing ED packaging, increasing ED prices, reducing visibility in retail outlets, and research and education. Because many countries allow the sale of EDs to people aged consumption. In addition to more research and education, these strategies included policy changes targeting ED sales, packaging, price, and visibility. Future research might examine the feasibility of implementing such interventions. Copyright © 2017 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  11. The Meaning of Work among Chinese University Students: Findings from Prototype Research Methodology

    Science.gov (United States)

    Zhou, Sili; Leung, S. Alvin; Li, Xu

    2012-01-01

    This study examined Chinese university students' conceptualization of the meaning of work. One hundred and ninety students (93 male, 97 female) from Beijing, China, participated in the study. Prototype research methodology (J. Li, 2001) was used to explore the meaning of work and the associations among the identified meanings. Cluster analysis was…

  12. Census of Institutional Repositories in the United States: MIRACLE Project Research Findings. CLIR Publication No. 140

    Science.gov (United States)

    Markey, Karen; Rieh, Soo Young; St. Jean, Beth; Kim, Jihyun; Yakel, Elizabeth

    2007-01-01

    In this report, the authors describe results of a nationwide census of institutional repositories in U.S. academic institutions. The census is one of several activities of the MIRACLE Project, an Institute of Museum and Library Services (IMLS)-funded research program based at the University of Michigan. The acronym MIRACLE means "Making…

  13. The influence of plants on productivity : A critical assessment of research findings and test methods

    NARCIS (Netherlands)

    Bakker, I; van der Voordt, Theo

    2010-01-01

    Purpose
    This paper aims to review available research into the impact of plants on people and labour productivity in order to test a number of hypotheses and the reliability and validity of “evidence based” statements.
    Methodology
    An extended literature review has been conducted of

  14. The Challenge of Finding Faculty Time for Applied Research Activities in Ontario Colleges

    Science.gov (United States)

    Rosenkrantz, Otte

    2013-01-01

    The purpose of this study was to explore how the role of Ontario college faculty has evolved since the advent of the Post-Secondary Education Choice and Excellence Act of 2000 and the Colleges of Applied Arts and Technology Act of 2002 in terms of whether or not the decision to create a research culture at the colleges included making time…

  15. A rural virtual health sciences library project: research findings with implications for next generation library services*

    OpenAIRE

    Richwine, Margaret (Peggy); McGowan, Julie J.

    2001-01-01

    Purpose: The Shared Hospital Electronic Library of Southern Indiana (SHELSI) research project was designed to determine whether access to a virtual health sciences library and training in its use would support medical decision making in rural southern Indiana and achieve the same level of impact seen by targeted information services provided by health sciences librarians in urban hospitals.

  16. The Planning of Teaching in the Context of Lesson Study: Research Findings

    Science.gov (United States)

    Kanellopoulou, Eurydice-Maria; Darra, Maria

    2018-01-01

    The main purpose of the present study is to examine the attitudes, perceptions and experiences of the teachers participating in the planning of teaching in the context of the Lesson Study. The present work, which is part of a wider research effort, followed a mixed methodological planning for reasons of triangulation. The survey was conducted from…

  17. Can We Find Solutions with People? Participatory Action Research with Small Organic Producers in Andalusia

    Science.gov (United States)

    Cuellar-Padilla, Mamen; Calle-Collado, Angel

    2011-01-01

    This paper reports on an experiment linking science with people. Taking as a paradigm the holistic scientific approach fostered by agroecology, we present a methodological proposal for the implementation of participatory action research in rural areas. Our aims were various: to solve a specific problem, i.e. the exclusion of small- and…

  18. Analysing Personal Characteristics of Lone-Actor Terrorists : Research Findings and Recommendations

    NARCIS (Netherlands)

    Roy, de van Zuijdewijn J.; Bakker, E.

    2016-01-01

    This Research Note presents the outcome of a project that looked at the personal characteristics of lone-actor terrorists. It is part of the larger Countering Lone-Actor Terrorism (CLAT) project. The project described here aimed to improve understanding of, and responses to, the phenomenon of

  19. Quality of the working environment and productivity : research findings and case studies

    NARCIS (Netherlands)

    Greef, M. de; Broek, K. van den; Jongkind, R.; Kenny, L.; Shechtman, O.; Kuhn, K.

    2004-01-01

    The purpose of this working paper, prepared by the Topic Centre on Research - Work and Health of the European Agency for Safety and Health at Work, is to look at the link between a good working environment and productivity. A better understanding of positive effects of a good working environment

  20. Better Together: Research Findings on the Relationship between Racial Justice Organizations and LGBT Communities. Report

    Science.gov (United States)

    Sen, Rinku; Wessler, Seth; Apollon, Dominique

    2010-01-01

    In partnership with the Arcus Foundation, the Applied Research Center (ARC) has undertaken a study of the relationship between racial justice organizations and lesbian/gay/bisexual/transgender (LGBT) constituencies and issues, with the understanding that communities of color themselves, including their LGBT members, have a good deal at stake in…

  1. The ABCs of Keeping on Track to Graduation: Research Findings from Baltimore

    Science.gov (United States)

    Mac Iver, Martha Abele; Messel, Matthew

    2013-01-01

    This study of graduation outcomes in Baltimore uses multivariate analysis of longitudinal student cohort data to examine the impact of factors identified in previous research as early warning indicators of a dropout outcome. Student cohort files were constructed from longitudinal administrative data (following all first-time 2004-2005 and…

  2. Teachers' Commitment To, and Experiences of, the Teaching Profession in Tanzania: Findings of Focus Group Research

    Science.gov (United States)

    Mkumbo, Kitila A. K.

    2012-01-01

    This qualitative study examined teachers' commitment to, and experiences of, the teaching profession in six regions of Tanzania. The study used focus group discussions as research method and data collection tool. Twenty four groups were conducted, with group membership ranging from five to nine participants. The results show that the teachers'…

  3. Highlights of the Russian health studies program and updated research findings

    International Nuclear Information System (INIS)

    Fountos, Barrett N.

    2017-01-01

    Recognized for conducting cutting-edge science in the field of radiation health effects research, the Department of Energy's (DOE) Russian Health Studies Program has continued to generate excitement and enthusiasm throughout its 23-year mission to assess worker and public health risks from radiation exposure resulting from nuclear weapons production activities in the former Soviet Union. The three goals of the Program are to: (1) clarify the relationship between health effects and chronic, low-to-medium dose radiation exposure; (2) estimate the cancer risks from exposure to gamma, neutron, and alpha radiation; and (3) provide information to the national and international organizations that determine radiation protection standards and practices. Research sponsored by DOE's Russian Health Studies Program is conducted under the authority of the Joint Coordinating Committee for Radiation Effects Research (JCCRER), a bi-national committee representing Federal agencies in the United States and the Russian Federation. Signed in 1994, the JCCRER Agreement established the legal basis for the collaborative research between USA and Russian scientists to determine the risks associated with working at or living near Russian former nuclear weapons production sites. The products of the Program are peer-reviewed publications on cancer risk estimates from worker and community exposure to ionizing radiation following the production of nuclear weapons in Russia. The scientific return on investment has been substantial. Through 31 December 2015, JCCRER researchers have published 299 peer-reviewed publications. To date, the research has focused on the Mayak Production Association (Mayak) in Ozersk, Russia, which is the site of the first Soviet nuclear weapons production facility, and people in surrounding communities along the Techa River. There are five current projects in the Russian Health Studies Program: two radiation epidemiology studies; two historical dose reconstruction

  4. End-of-Life care in a community garden: Findings from a Participatory Action Research project in regional Australia.

    Science.gov (United States)

    Marsh, Pauline; Gartrell, Gabrielle; Egg, Gwen; Nolan, Andrew; Cross, Merylin

    2017-05-01

    This article presents findings from research that explored how a community garden might function as a place of end-of-life and bereavement support. Adopting Participatory Action Research (PAR) methods, and informed by Third Place theory and notions of therapeutic landscape, creative consultations were held in the Garden and people's homes. The findings provide insights into the nature of informal care as it is played out in the liminal garden space, between home and institution. The results illuminate the therapeutic landscape of community gardens, and contribute new understandings to the fields of PAR, health geography and end-of-life care. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Calorie labeling in a rural middle school influences food selection: findings from community-based participatory research.

    Science.gov (United States)

    Hunsberger, Monica; McGinnis, Paul; Smith, Jamie; Beamer, Beth Ann; O'Malley, Jean

    2015-01-01

    Calorie labeling at the point-of-purchase in chain restaurants has been shown to reduce energy intake. To investigate the impact of point-of-purchase calorie information at one rural middle school. With a community-based participatory research framework a mixed method approach was used to evaluate the impact of point-of-purchase calorie information. Students in grades 6-8, dining at the school cafeteria January and February 2010, participated for 17 school days each month; in January a menu was offered in the usual manner without calorie labels; the same menu was prepared in February with the addition of calorie labels at point-of-purchase. Gross calories served per student were measured each day allowing for matched comparison by menu. In March/April of 2010, 32 students who ate in the cafeteria 3 or more times per week were interviewed regarding their views on menu labeling. Calorie consumption decreased by an average of 47 calories/day; fat intake reduced by 2.1 grams/day. Five main themes were consistent throughout the interviews. Point-of-purchase calorie labels can play a role in reducing the number of calories consumed by middle school age children at the lunch. The majority of students interviewed found the calorie labels helped them choose healthier food.

  6. Finding the right doctoral thesis - an innovative research fair for medical students.

    Science.gov (United States)

    Steffen, Julius; Grabbert, Markus; Pander, Tanja; Gradel, Maximilian; Köhler, Lisa-Maria; Fischer, Martin R; von der Borch, Philip; Dimitriadis, Konstantinos

    2015-01-01

    The importance of research, as promoted by the CanMEDS framework, is widely acknowledged. Many medical students in Germany work on a research project as part of their doctoral thesis whilst still going to medical school. However, a significant amount of projects are abandoned unfinished, which leads to substantial wastage of resources. One reason for this is an information deficit concerning undergraduate research projects. To counteract this, we introduced an annual event at LMU Munich called DoktaMed with more than 600 visitors each year. It combines medical convention and research fair including keynote lectures, workshops and poster sessions as well as an exhibition of research groups and institutes. DoktaMed is a peer-to-peer event organized by a team of 40 students. A needs analysis before its implementation underlined the information deficit as a possible cause for the high rate of abandoned projects. In the annual evaluation, visitors of DoktaMed rate the event with an average grade of 2.1 on a six-level Likert scale (n=558, SD=1.06, with "1=very good", "6=poor"). They stated to now feel better informed about the topic and regarded visiting DoktaMed as a worthwhile investment of time. Students are generally satisfied with the event and feel better informed after visiting DoktaMed. However, many students never visit DoktaMed for various reasons. A possible improvement would be to present a greater number of clinical studies in addition to the laboratory work that DoktaMed focuses on now. Evaluation after six years of DoktaMed is very promising. Visitors seem to be better informed. Nevertheless there is space for improvement in order to get more students and more faculty members involved. More studies are needed to assess long-term effects.

  7. Finding the right doctoral thesis – an innovative research fair for medical students

    Directory of Open Access Journals (Sweden)

    Steffen, Julius

    2015-08-01

    Full Text Available Introduction: The importance of research, as promoted by the framework, is widely acknowledged. Many medical students in Germany work on a research project as part of their doctoral thesis whilst still going to medical school. However, a significant amount of projects are abandoned unfinished, which leads to substantial wastage of resources. One reason for this is an information deficit concerning undergraduate research projects.Project description: To counteract this, we introduced an annual event at LMU Munich called with more than 600 visitors each year. It combines medical convention and research fair including keynote lectures, workshops and poster sessions as well as an exhibition of research groups and institutes. is a peer-to-peer event organized by a team of 40 students. Results: A needs analysis before its implementation underlined the information deficit as a possible cause for the high rate of abandoned projects. In the annual evaluation, visitors of rate the event with an average grade of 2.1 on a six-level Likert scale (n=558, SD=1.06, with "1=very good", "6=poor". They stated to now feel better informed about the topic and regarded visiting as a worthwhile investment of time.Discussion: Students are generally satisfied with the event and feel better informed after visiting . However, many students never visit DoktaMed for various reasons. A possible improvement would be to present a greater number of clinical studies in addition to the laboratory work that focuses on now.Conclusion: Evaluation after six years of is very promising. Visitors seem to be better informed. Nevertheless there is space for improvement in order to get more students and more faculty members involved. More studies are needed to assess long-term effects.

  8. Methodically finding solutions of equipments for carrying out experiments in materials testing and research. Pt. 2

    International Nuclear Information System (INIS)

    Findeisen, D.; Nachtweide, D.; Kuntze, G.

    1983-01-01

    In comparison with the development of industrial products the development of test equipments is of special kind, which is demonstrated by methodical proceeding for finding solutions and by potentialities for technical design and production of test equipment engineering. Some general principles are turned out and explained by several realized examples of design belonging to the sphere of materials testing in den Federal Institute of Materials Testing (BAM) representative of other problems. User are large scientific institutes independent of university, scientific institutes as members of university just as test stands and quality control offices of industrial works. (orig.) [de

  9. The Internet as a Source of Academic Research Information: Findings of Two Pilot Studies

    Directory of Open Access Journals (Sweden)

    Harry M. Kibirige

    2017-09-01

    Full Text Available As a source of serious subject-oriented information, the Internet has been a powerful feature in the information arena since its inception in the last quarter of the twentieth century. It was, however, initially restricted to government contractors or major research universities operating under the aegis of the Advanced Research Projects Network (ARPANET.(1 In the 1990s, the content and use of the Internet was expanded to includemundane subjects covered in business, industry, education,government, entertainment, and a host of otherareas. It has become a magnanimous network of networks the measurement of whose size, impact, and content often elude serious scholarly effort.(2 Opening the Internet to common usage literally opened the flood gates of what has come to be known as the information superhighway. Currently, there is virtually no subject that cannot be found on the Internet in one form or another.

  10. Bioremediation via Methanotrophy: Overview of Recent Findings and Suggestions for Future Research

    Directory of Open Access Journals (Sweden)

    Jeremy eSemrau

    2011-10-01

    Full Text Available Microbially-mediated bioremediation of polluted sites has been a subject of much research over the past 30 years, with many different compounds shown to be degraded under both aerobic and anaerobic conditions. Aerobic-mediated bioremediation commonly examines the use of methanotrophs, microorganisms that consume methane as their sole source of carbon and energy. Given the diverse environments in which methanotrophs have been found, the range of substrates they can degrade and the fact that they can be easily stimulated with the provision of methane and oxygen, these microorganisms in particular have been examined for aerobic degradation of chlorinated hydrocarbons. The physiological and phylogenetic diversity of methanotrophy, however, has increased substantially in just the past five years. Here in this review, the current state of knowledge of methanotrophy, particularly as it applies to pollutant degradation is summarized, and suggestions for future research provided.

  11. Requirements Engineering as Creative Problem Solving: A Research Agenda for Idea Finding

    OpenAIRE

    Maiden, N.; Jones, S.; Karlsen, I. K.; Neill, R.; Zachos, K.; Milne, A.

    2010-01-01

    This vision paper frames requirements engineering as a creative problem solving process. Its purpose is to enable requirements researchers and practitioners to recruit relevant theories, models, techniques and tools from creative problem solving to understand and support requirements processes more effectively. It uses 4 drivers to motivate the case for requirements engineering as a creative problem solving process. It then maps established requirements activities onto one of the longest-esta...

  12. Finding CreativeVoice: Applying Arts-Based Research in the Context of Biodiversity Conservation

    Directory of Open Access Journals (Sweden)

    Flor Rivera Lopez

    2018-05-01

    Full Text Available The integration of creative arts–based methods into scientific research offers a host of advantages, including the ability to capture the complex texture of lived experience, explore interconnections between nature and culture, support nonhierarchical relations, and communicate insights in engaging and empowering new ways. In this article, we describe a new method—CreativeVoice—integrating the creative arts and qualitative research, which we developed and applied in a context of pursuing community-based conservation of agricultural biodiversity. We developed CreativeVoice as an integrative method to help us understand the local contexts, cultures, and perspectives from community members of different ages and genders, in two contrasting farming communities in Oaxaca, Mexico. CreativeVoice effectively adapts and extends the Photovoice method so as to retain its benefits but address some of its limitations. This includes allowing participants to choose a genre of artistic expression connected to their own specific individual or cultural contexts and providing the capacity to move beyond capturing present-day realities to directly bring in connections to the past and visions for the future. This article describes both the CreativeVoice approach and the significant value of integrating arts-based methods into research for advancing sustainability.

  13. Newborn Care in the Home and Health Facility: Formative Findings for Intervention Research in Cambodia

    Directory of Open Access Journals (Sweden)

    Alessandra N. Bazzano

    2016-12-01

    Full Text Available Global coverage and scale up of interventions to reduce newborn mortality remains low, though progress has been achieved in improving newborn survival in many low-income settings. An important factor in the success of newborn health interventions, and moving to scale, is appropriate design of community-based programs and strategies for local implementation. We report the results of formative research undertaken to inform the design of a newborn health intervention in Cambodia. Information was gathered on newborn care practices over a period of three months using multiple qualitative methods of data collection in the primary health facility and home setting. Analysis of the data indicated important gaps, both at home and facility level, between recommended newborn care practices and those typical in the study area. The results of this formative research have informed strategies for behavior change and improving referral of sick infants in the subsequent implementation study. Collection and dissemination of data on newborn care practices from settings such as these can contribute to efforts to advance survival, growth and development of newborns for intervention research, and for future newborn health programming.

  14. Scientific Productivity on Research in Ethical Issues over the Past Half Century: A JoinPoint Regression Analysis.

    Science.gov (United States)

    Long, Nguyen Phuoc; Huy, Nguyen Tien; Trang, Nguyen Thi Huyen; Luan, Nguyen Thien; Anh, Nguyen Hoang; Nghi, Tran Diem; Hieu, Mai Van; Hirayama, Kenji; Karbwang, Juntra

    2014-09-01

    Ethics is one of the main pillars in the development of science. We performed a JoinPoint regression analysis to analyze the trends of ethical issue research over the past half century. The question is whether ethical issues are neglected despite their importance in modern research. PubMed electronic library was used to retrieve publications of all fields and ethical issues. JoinPoint regression analysis was used to identify the significant time trends of publications of all fields and ethical issues, as well as the proportion of publications on ethical issues to all fields over the past half century. Annual percent changes (APC) were computed with their 95% confidence intervals, and a p-value years (from 1996 to 2013). When comparing the absolute number of ethics related articles (APEI) to all publications of all fields (APAF) on PubMed, the results showed that the proportion of APEI to APAF statistically increased during the periods of 1965-1974, 1974-1986, and 1986-1993, with APCs of 11.0, 2.1, and 8.8, respectively. However, the trend has gradually dropped since 1993 and shown a marked decrease from 2002 to 2013 with an annual percent change of -7.4%. Scientific productivity in ethical issues research on over the past half century rapidly increased during the first 30-year period but has recently been in decline. Since ethics is an important aspect of scientific research, we suggest that greater attention is needed in order to emphasize the role of ethics in modern research.

  15. The conceptual analysis of the instructional process: Research findings on students’ teacher reflections in art education

    Directory of Open Access Journals (Sweden)

    Lucie Hajdušková

    2010-12-01

    Full Text Available The paper focuses on the linking pedagogical theory to teaching practicewith the aim to improve quality of education through its analytic reflection by teachersor student teachers. The text deals with the original method of didactic reflection– concept analysis. Concept analysis is characterized as a methodical instrument forreflection and evaluation of the instruction. It is based on investigation of didacticcontent transformation in educational processes and it is oriented to creative approachand experiential learning in the instruction. The explanation uses the results of research(2009–2010 on the state of didactic skills and pedagogical content knowledge of arteducation teachers during their didactic training.

  16. New findings and setting the research agenda for soil and water conservation for sustainable land management

    Science.gov (United States)

    Keesstra, Saskia; Argaman, Eli; Gomez, Jose Alfonso; Quinton, John

    2014-05-01

    The session on soil and water conservation for sustainable land management provides insights into the current research producing viable measures for sustainable land management and enhancing the lands role as provider of ecosystem services. The insights into degradation processes are essential for designing and implementing feasible measures to mitigate against degradation of the land resource and adapt to the changing environment. Land degradation occurs due to multiple pressures on the land, such as population growth, land-use and land-cover changes, climate change and over exploitation of resources, often resulting in soil erosion due to water and wind, which occurs in many parts of the world. Understanding the processes of soil erosion by wind and water and the social and economic constraints faced by farmers forms an essential component of integrated land development projects. Soil and water conservation measures are only viable and sustainable if local environmental and socio-economic conditions are taken into account and proper enabling conditions and policies can be achieved. Land degradation increasingly occurs because land use, and farming systems are subject to rapid environmental and socio-economic changes without implementation of appropriate soil and water conservation technologies. Land use and its management are thus inextricably bound up with development; farmers must adapt in order to sustain the quality of their, and their families, lives. In broader perspective, soil and water conservation is needed as regulating ecosystem service and as a tool to enhance food security and biodiversity. Since land degradation occurs in many parts of the world and threatens food production and environmental stability it affects those countries with poorer soils and resilience in the agriculture sector first. Often these are the least developed countries. Therefore the work from researchers from developing countries together with knowledge from other disciplines

  17. An Example of the Use of Research Methods and Findings as an Experiential Learning Exercise in an Accounting Theory Course

    Science.gov (United States)

    Bublitz, Bruce; Philipich, Kirk; Blatz, Robert

    2015-01-01

    The purpose of this teaching note is to describe an experiential learning exercise used in a master's level financial accounting theory course. The experiential exercise illustrates how order effects can affect user's judgments, a long-standing research finding. This experiential exercise was used in an attempt to make students more cognizant of…

  18. Statement Summarizing Research Findings on the Issue of the Relationship Between Food-Additive-Free Diets and Hyperkinesis in Children.

    Science.gov (United States)

    Lipton, Morris; Wender, Esther

    The National Advisory Committee on Hyperkinesis and Food Additives paper summarized some research findings on the issue of the relationship between food-additive-free diets and hyperkinesis in children. Based on several challenge studies, it is concluded that the evidence generally refutes Dr. B. F. Feingold's claim that artificial colorings in…

  19. Findings of Visual Arts Research in Early Childhood and Primary Education

    Directory of Open Access Journals (Sweden)

    Marijana Županić Benić

    2016-12-01

    Full Text Available Arts research was introduced in the field of education during the 1990s by Barone and Eisner, but their methodology is rarely used because it is not considered to be consistent with traditional paradigms of the scientific method. This review identified only seven visual arts research studies in early childhood education and primary education. Four studies were conducted in early childhood education settings, and two of those studies used quantitative methods to investigate the effects of art on early childhood development. The three studies that were conducted in primary education used a case study approach to examine art projects in the community or the classroom. Participation in visual arts was associated with enhanced learning outcomes in other areas and the development of individual and social competences, but it was not found to facilitate the development of age-dependent abilities, such as visual or grapho-motor abilities. Visual arts also proved to be an effective method of communication for children in preschool and primary education institutions because it is easier for them to express their opinions and beliefs to adults with visual media than with words.

  20. Evaluation applications of instrument calibration research findings in psychology for very small samples

    Science.gov (United States)

    Fisher, W. P., Jr.; Petry, P.

    2016-11-01

    Many published research studies document item calibration invariance across samples using Rasch's probabilistic models for measurement. A new approach to outcomes evaluation for very small samples was employed for two workshop series focused on stress reduction and joyful living conducted for health system employees and caregivers since 2012. Rasch-calibrated self-report instruments measuring depression, anxiety and stress, and the joyful living effects of mindfulness behaviors were identified in peer-reviewed journal articles. Items from one instrument were modified for use with a US population, other items were simplified, and some new items were written. Participants provided ratings of their depression, anxiety and stress, and the effects of their mindfulness behaviors before and after each workshop series. The numbers of participants providing both pre- and post-workshop data were low (16 and 14). Analysis of these small data sets produce results showing that, with some exceptions, the item hierarchies defining the constructs retained the same invariant profiles they had exhibited in the published research (correlations (not disattenuated) range from 0.85 to 0.96). In addition, comparisons of the pre- and post-workshop measures for the three constructs showed substantively and statistically significant changes. Implications for program evaluation comparisons, quality improvement efforts, and the organization of communications concerning outcomes in clinical fields are explored.

  1. Synergies, strengths and challenges: findings on community capability from a systematic health systems research literature review

    Directory of Open Access Journals (Sweden)

    Asha S. George

    2016-11-01

    Full Text Available Abstract Background Community capability is the combined influence of a community’s social systems and collective resources that can address community problems and broaden community opportunities. We frame it as consisting of three domains that together support community empowerment: what communities have; how communities act; and for whom communities act. We sought to further understand these domains through a secondary analysis of a previous systematic review on community participation in health systems interventions in low and middle income countries (LMICs. Methods We searched for journal articles published between 2000 and 2012 related to the concepts of “community”, “capability/participation”, “health systems research” and “LMIC.” We identified 64 with rich accounts of community participation involving service delivery and governance in health systems research for thematic analysis following the three domains framing community capability. Results When considering what communities have, articles reported external linkages as the most frequently gained resource, especially when partnerships resulted in more community power over the intervention. In contrast, financial assets were the least mentioned, despite their importance for sustainability. With how communities act, articles discussed challenges of ensuring inclusive participation and detailed strategies to improve inclusiveness. Very little was reported about strengthening community cohesiveness and collective efficacy despite their importance in community initiatives. When reviewing for whom communities act, the importance of strong local leadership was mentioned frequently, while conflict resolution strategies and skills were rarely discussed. Synergies were found across these elements of community capability, with tangible success in one area leading to positive changes in another. Access to information and opportunities to develop skills were crucial to community

  2. What Counts in After School? Findings from the Massachusetts Afterschool Research Study (MARS

    Directory of Open Access Journals (Sweden)

    Beth M. Miller

    2007-03-01

    Full Text Available This article discusses the Massachusetts Afterschool Research Study (MARS. Conducted during 2003-2005, MARS took an in-depth look at program structure and quality in 78 varied programs across Massachusetts, using data sources that included interviews with program directors, afterschool program site observations, school district student data, attendance data, and surveys with afterschool program staff, day school teachers, and afterschool program youth. The MARS study offers many useful insights into what afterschool programs look like, approaches to providing high quality experiences for youth, and the connections between high quality and improved outcomes for the young people attending these programs. The results may be useful to programs, policy makers, and others in the field by deepening our understanding of how youth participation leads to a variety of youth outcomes.

  3. Disaster media coverage and psychological outcomes: descriptive findings in the extant research.

    Science.gov (United States)

    Pfefferbaum, Betty; Newman, Elana; Nelson, Summer D; Nitiéma, Pascal; Pfefferbaum, Rose L; Rahman, Ambreen

    2014-09-01

    This review of the literature on disaster media coverage describes the events, samples, and forms of media coverage (television, newspapers, radio, internet) studied and examines the association between media consumption and psychological outcomes. A total of 36 studies representing both man-made and natural events met criteria for review in this analysis. Most studies examined disaster television viewing in the context of terrorism and explored a range of outcomes including posttraumatic stress disorder (PTSD) caseness and posttraumatic stress (PTS), depression, anxiety, stress reactions, and substance use. There is good evidence establishing a relationship between disaster television viewing and various psychological outcomes, especially PTSD caseness and PTS, but studies are too few to draw definitive conclusions about the other forms of media coverage that have been examined. As media technology continues to advance, future research is needed to investigate these additional media forms especially newer forms such as social media.

  4. Informed consent for exome sequencing research in families with genetic disease: the emerging issue of incidental findings.

    Science.gov (United States)

    Bergner, Amanda L; Bollinger, Juli; Raraigh, Karen S; Tichnell, Crystal; Murray, Brittney; Blout, Carrie Lynn; Telegrafi, Aida Bytyci; James, Cynthia A

    2014-11-01

    Genomic sequencing technology is increasingly used in genetic research. Studies of informed consent for exome and genome sequencing (ES/GS) research have largely involved hypothetical scenarios or healthy individuals enrolling in population-based studies. Studies have yet to explore the consent experiences of adults with inherited disease. We conducted a qualitative interview study of 15 adults recently enrolled in a large-scale ES/GS study (11 affected adults, four parents of affected children). Our study had two goals: (1) to explore three theoretical barriers to consent for ES/GS research (interpretive/technical complexity, possibility of incidental findings, and risks of loss of privacy); and (2) to explore how interviewees experienced the consent process. Interviewees could articulate study goals and processes, describe incidental findings, discuss risks of privacy loss, and reflect on their consent experience. Few expected the study would identify the genetic cause of their condition. All elected to receive incidental findings. Interviewees acknowledged paying little attention to potential implications of incidental findings in light of more pressing goals of supporting research regarding their own medical conditions. Interviewees suggested that experience living with a genetic condition prepared them to adjust to incidental findings. Interviewees also expressed little concern about loss of confidentiality of study data. Some experienced the consent process as very long. None desired reconsent prior to return of study results. Families with inherited disease likely would benefit from a consent process in which study risks and benefits were discussed in the context of prior experiences with genetic research and genetic disease. © 2014 Wiley Periodicals, Inc.

  5. Exploring arts-based knowledge translation: sharing research findings through performing the patterns, rehearsing the results, staging the synthesis.

    Science.gov (United States)

    Rieger, Kendra; Schultz, Annette S H

    2014-04-01

    Cultivation of knowledge translation (KT) strategies that actively engage health professionals in critical reflection of their practice and research-based evidence are imperative to address the research-practice gap. While research-based evidence is exponentially growing, our ability to facilitate uptake by nurses and other health professionals has not kept pace. Innovative approaches that extend epistemological bias beyond a singular standpoint of postpositivism, such as the utilization of arts-based methods, expand the possibility to address the complexities of context, engage audience members, promote dissemination within communities of practice, and foster new audiences interested in research findings. In this paper, we address the importance of adopting a social constructivist epistemological stance to facilitate knowledge translation to diverse audiences, explore various arts-based knowledge translation (ABKT) strategies, and open a dialogue concerning evaluative tenets of ABKT. ABKT utilizes various art forms to disseminate research knowledge to diverse audiences and promote evidence-informed practice. ABKT initiatives translate knowledge not based upon a linear model, which views knowledge as an objective entity, but rather operate from the premise that knowledge is socially situated, which demands acknowledging and engaging the learner within their context. Theatre, dance, photography, and poetry are art forms that are commonly used to communicate research findings to diverse audiences. Given the emerging interest and importance of utilizing this KT strategy situated within a social constructivist epistemology, potential challenges and plausible evaluative criteria specific to ABKT are presented. ABKT is an emerging KT strategy that is grounded in social constructivist epistemological tenets, and holds potential for meaningfully sharing new research knowledge with diverse audiences. ABKT is an innovative and synergistic approach to traditional

  6. EMSODEV and EPOS-IP: key findings for effective management of EU research infrastructure projects

    Science.gov (United States)

    Materia, Paola; Bozzoli, Sabrina; Beranzoli, Laura; Cocco, Massimo; Favali, Paolo; Freda, Carmela; Sangianantoni, Agata

    2017-04-01

    EMSO (European Multidisciplinary Seafloor and water-column Observatory, http://www.emso-eu.org) and EPOS (European Plate Observing System, https://www.epos-ip.org) are pan-European Research Infrastructures (RIs) in the ESFRI 2016 Roadmap. EMSO has recently become an ERIC (European Research Infrastructure Consortium), whilst EPOS application is in progress. Both ERICs will be hosted in Italy and the "Representing Entity" is INGV. EMSO consists of oceanic environment observation systems spanning from the Arctic through the Atlantic and Mediterranean, to the Black Sea for long-term, high-resolution, real-time monitoring of natural and man-induced processes such as hazards, climate, and marine ecosystems changes to study their evolution and interconnections. EPOS aims at creating a pan-European infrastructure for solid Earth science to support a safe and sustainable society. EPOS will enable innovative multidisciplinary research for a better understanding of Earth's physical and chemical processes controlling earthquakes, volcanic eruptions, ground instability, tsunami, and all those processes driving tectonics and Earth's surface dynamics. Following the conclusion of their Preparatory Phases the two RIs are now in their Implementation Phase still supported by the EC through the EMSODEV and EPOS-IP projects, both run by dedicated Project Management Offices at INGV with sound experience in EU projects. EMSODEV (H2020 project, 2015-2018) involves 11 partners and 9 associate partners and aims at improving the harmonization among the EMSO ERIC observation systems through the realization of EMSO Generic Instrument Modules (EGIMs), and a Data Management Platform (DMP) to implement interoperability and standardization. The DMP will provide access to data from all EMSO nodes, providing a unified, homogeneous, infrastructure-scale and user-oriented platform integrated with the increased measurement capabilities and functions provided by the EGIMs. EPOS IP (H2020 project, 2015

  7. Soil erosion and degradation in Mediterranean Type Ecosystems. The Soil Erosion and Degradation Research Group (SEDER) approach and findings

    Science.gov (United States)

    Cerdà, Artemi; Keesstra, Saskia; Pulido, Manuel; Jordán, Antonio; Novara, Agata; Giménez-Morera, Antonio; Borja, Manuel Esteban Lucas; Francisco Martínez-Murillo, Juan; Rodrigo-Comino, Jesús; Pereira, Paulo; Nadal-Romero, Estela; Taguas, Tani; Úbeda, Xavier; Brevik, Eric C.; Tarolli, Paolo; Bagarello, Vicenzo; Parras Alcantara, Luis; Muñoz-Rojas, Miriam; Oliva, Marc; di Prima, Simone

    2017-04-01

    The Soil Erosion and Degradation Reseach Group (SEDER) is developing a research program since 2002 to assess the soil erosion and degradation processes at the Canyoles River watershed in Eastern Spain. The research study site was selected as representative of the environmental changes that take place in the Mediterranean: abandonment of the agriculture land in the mountains, forest fire expansion, intensification of the agriculture, impact of the infraesturctures such as rail and road embankments, and soil sealing due to the urban expansion. The research is based on the continuous measurements in the Montesa and El Teularet research stations and the sampling of the soils, topographical measurements and the use of rainfall simulators, minidisk infiltrometers, ring infiltrometers and Water Drop Penetration Time tests. The research is moving from a pure scientific approach to a more socio-economic view, and the stakeholders are being researched from a perception point of view. SEDER is also moving from pure to applied science, with the objective to design new managements that will satisfy the stakeholders and will achieve the sustainability. The research is being carried out in vineyards and orchards as they show extremely high erosion rates. But also we are interested in the impact of forest fires and the road embankments. In all three research topics, SEDER wish to find the sustainable managements. Acknowledgements The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 603498 (RECARE project) and the CGL2013- 47862-C2-1-R and CGL2016-75178-C2-2-R national research projects. References Bodí, M. B., Martin, D. A., Balfour, V. N., Santín, C., Doerr, S. H., Pereira, P., . . . Mataix-Solera, J. (2014). Corrigendum to "wildland fire ash: Production, composition and eco-hydro-geomorphic effects", earth sci. rev. 130 (2014) [103-127]. Earth-Science Reviews, 138, 503. doi:10

  8. Why public information works: Research findings on organizational and individual impact

    International Nuclear Information System (INIS)

    Bisconti, A.S.

    1989-01-01

    Broad and growing public recognition of the importance of nuclear energy in the United States is evident in the public opinion polls, continued defeat of antinuclear referenda, positive Congressional actions, and open support by politicians-from the National Conference of State Legislatures to President Bush. At leadership levels, the need to address the looming electricity crisis without increasing dependence on foreign oil or greenhouse gas emissions is being voiced increasingly. Within this context, the industry is beginning to be successful in getting its message across to the American public through national advertising and media and public relations programs of the U.S. Council for Energy Awareness (USCEA). And the author knows that the American Nuclear Society (ANS) Public Information Committee is working hard in complementary kinds of public education. Research shows that the public's attitudes toward nuclear energy become more favorable when they are exposed to public information and that a more active scientific community could greatly increase public recognition of the benefits that nuclear energy provides

  9. Finding an optimization of the plate element of Egyptian research reactor using genetic algorithm

    International Nuclear Information System (INIS)

    Wahed, M.; Ibrahim, W.; Effat, A.

    2008-01-01

    The second Egyptian research reactor ET-RR-2 went critical on the 27th of November 1997. The National Center of Nuclear Safety and Radiation Control (NCNSRC) has the responsibility of the evaluation and assessment of the safety of this reactor. The purpose of this paper is to present an approach to optimization of the fuel element plate. For an efficient search through the solution space we use a multi objective genetic algorithm which allows us to identify a set of Pareto optimal solutions providing the decision maker with the complete spectrum of optimal solutions with respect to the various targets. The aim of this paper is to propose a new approach for optimizing the fuel element plate in the reactor. The fuel element plate is designed with a view to improve reliability and lifetime and it is one of the most important elements during the shut down. In this present paper, we present a conceptual design approach for fuel element plate, in conjunction with a genetic algorithm to obtain a fuel plate that maximizes a fitness value to optimize the safety design of the fuel plate. (authors)

  10. Environmental policy instruments and technological change in the energy sector: findings from comparative empirical research

    International Nuclear Information System (INIS)

    Skjaerseth, J.B.; Christiansen, A.C.

    2006-01-01

    This article explores the extent to which and in what ways environmental policy instruments may affect patterns of environmental friendly technological change in the energy sector. Our argument is based on the assumption, however, that technological change is also affected by the political context in which the instruments are applied and by the nature of the problem itself. Comparative empirical research involving different European countries, sectors and policy fields were examined, including climate change, air pollution and wind power. The relationship between environmental policy instruments and technological change is extremely complex, not least due to the impact of other factors that may be more decisive than environmental ones. Against this backdrop, it was concluded that: 1) a portfolio of policy instruments works to the extent that different types of policy instruments affect the different drivers and stages behind technological change needed to solve specific problems. The need for a portfolio of policy instruments depends on the technological challenge being faced; 2) voluntary approaches facilitated constructive corporate strategies, but mandatory approaches tended to be more effective in stimulating short term major technological change; 3) voluntary approaches work well in the short term when the problem to be solved is characterized by lack of information and coordination. (author)

  11. Finding cancer driver mutations in the era of big data research.

    Science.gov (United States)

    Poulos, Rebecca C; Wong, Jason W H

    2018-04-02

    In the last decade, the costs of genome sequencing have decreased considerably. The commencement of large-scale cancer sequencing projects has enabled cancer genomics to join the big data revolution. One of the challenges still facing cancer genomics research is determining which are the driver mutations in an individual cancer, as these contribute only a small subset of the overall mutation profile of a tumour. Focusing primarily on somatic single nucleotide mutations in this review, we consider both coding and non-coding driver mutations, and discuss how such mutations might be identified from cancer sequencing datasets. We describe some of the tools and database that are available for the annotation of somatic variants and the identification of cancer driver genes. We also address the use of genome-wide variation in mutation load to establish background mutation rates from which to identify driver mutations under positive selection. Finally, we describe the ways in which mutational signatures can act as clues for the identification of cancer drivers, as these mutations may cause, or arise from, certain mutational processes. By defining the molecular changes responsible for driving cancer development, new cancer treatment strategies may be developed or novel preventative measures proposed.

  12. A rural virtual health sciences library project: research findings with implications for next generation library services.

    Science.gov (United States)

    Richwine, M P; McGowan, J J

    2001-01-01

    The Shared Hospital Electronic Library of Southern Indiana (SHELSI) research project was designed to determine whether access to a virtual health sciences library and training in its use would support medical decision making in rural southern Indiana and achieve the same level of impact seen by targeted information services provided by health sciences librarians in urban hospitals. Based on the results of a needs assessment, a virtual medical library was created; various levels of training were provided. Virtual library users were asked to complete a Likert-type survey, which included questions on intent of use and impact of use. At the conclusion of the project period, structured interviews were conducted. Impact of the virtual health sciences library showed a strong correlation with the impact of information provided by health sciences librarians. Both interventions resulted in avoidance of adverse health events. Data collected from the structured interviews confirmed the perceived value of the virtual library. While librarians continue to hold a strong position in supporting information access for health care providers, their roles in the information age must begin to move away from providing information toward selecting and organizing knowledge resources and instruction in their use.

  13. A rural virtual health sciences library project: research findings with implications for next generation library services*

    Science.gov (United States)

    Richwine, Margaret (Peggy); McGowan, Julie J.

    2001-01-01

    Purpose: The Shared Hospital Electronic Library of Southern Indiana (SHELSI) research project was designed to determine whether access to a virtual health sciences library and training in its use would support medical decision making in rural southern Indiana and achieve the same level of impact seen by targeted information services provided by health sciences librarians in urban hospitals. Methods: Based on the results of a needs assessment, a virtual medical library was created; various levels of training were provided. Virtual library users were asked to complete a Likert-type survey, which included questions on intent of use and impact of use. At the conclusion of the project period, structured interviews were conducted. Results: Impact of the virtual health sciences library showed a strong correlation with the impact of information provided by health sciences librarians. Both interventions resulted in avoidance of adverse health events. Data collected from the structured interviews confirmed the perceived value of the virtual library. Conclusion: While librarians continue to hold a strong position in supporting information access for health care providers, their roles in the information age must begin to move away from providing information toward selecting and organizing knowledge resources and instruction in their use. PMID:11209799

  14. On norms and bodies: findings from field research on cosmetic surgery in Rio de Janeiro, Brazil.

    Science.gov (United States)

    Dorneles de Andrade, Daniela

    2010-05-01

    Brazil has the second highest rate of cosmetic surgery worldwide, provided in a large number of public and private clinics and hospitals, especially in the southeast. This qualitative field research in Rio de Janeiro included participant observation and in-depth interviews with 18 women cosmetic surgery patients, 10 key informants (e.g. psychologists and sociologists) and 12 plastic surgeons. Fifteen of the women were either pre- or post-operative; three had not decided whether to have surgery. When asked about their motivations and expectations of the surgery, the majority of the women said they wanted to be "normal". Most of the surgeons said they acted as empathic companions from decision-making through surgery and beyond. Many of the key informants were critical of what was happening to medical ethics in relation to cosmetic surgery. With the growth in a consumer culture, they saw ethics in medicine becoming more bendable and subject to the "law" of the market. The cult of the body has become a mass phenomenon and taken on an important social dimension in a society where norms and images are broadcast widely by the media. The trend towards body-modification by cosmetic surgery at an early age is increasing dramatically. What demands critical thinking and further investigation are the consequences of cosmetic surgery for physical and mental health. Copyright 2010 Reproductive Health Matters. Published by Elsevier Ltd. All rights reserved.

  15. Construction ages of the Upton Stone Chamber: Preliminary findings and suggestions for future luminescence research

    Science.gov (United States)

    Mahan, Shannon; Martin, Frederick; Taylor, Cathy

    2015-01-01

    The Upton Chamber in Massachusetts, an earth-covered stone structure 3.4 meters (m) in diameter, with a corbelled stone dome, and a 4.3 m long entrance passageway, is studied with the aim of determining whether optically stimulated luminescence (OSL) dating methods can be used to establish the approximate construction date of the entranceway. Three samples, taken from soil behind the lowest stones in the wall of the entrance passageway, returned OSL ages between 385 and 660 years ago (or from 1625 A.D. to 1350 A.D.; using the year 2011 as the 0 year). One sample, taken below the bottom of the artifact layers in an archeological test pit in front of the chamber entrance, returned OSL ages between 650 and 880 years ago. A modern sample collected from a nearby fluvial channel returned an age between 55 and 175 years. The Upton Chamber OSL sampling results are challenging to interpret because there are mixtures in the samples of both younger and older grains that likely result from human modification, root or soil processes, animal bioturbation (i.e. ants and worms), and/or partial bleaching. The ages were determined using the lowest component of the finite mixture model as applied to a distribution of quartz grains. Further research may enable us to determine whether older components are of anthropomorphic or geological origin.

  16. Factors associated with home hazards: Findings from the Malaysian Elders Longitudinal Research study.

    Science.gov (United States)

    Romli, Muhammad H; Tan, Maw P; Mackenzie, Lynette; Lovarini, Meryl; Kamaruzzaman, Shahrul B; Clemson, Lindy

    2018-03-01

    Previous studies have investigated home hazards as a risk factor for falls without considering factors associated with the presence of home hazards. The present study aimed to determine patterns of home hazards among urban community-dwelling older Malaysians, and to identify factors contributing to home hazards. Cross-sectional data from the initial wave of the Malaysian Elders Longitudinal Research study were used. Basic demographics were obtained from the Global Questionnaire. Basic and instrumental activities of daily living were measured using the Katz and Lawton-Brody scales, and home hazards were identified using the Home Falls and Accidents Screening Tool. Participants were also asked if they had fallen in the previous 12 months. Data were analyzed from 1489 participants. Hazards were frequently identified (>30%) in the toilet and bathroom areas (no grab rail, no non-slip mat, distant toilet), slippery floors, no bedside light access and inappropriate footwear. Lower educational attainment, traditional housing, Chinese ethnicity, greater number of home occupants, lower monthly expenditure, poor vision and younger age were the factors independently associated with home hazards. This study provides evidence that home hazards are a product of the interaction of the individual's function within their home environment. Hazards are also influenced by local sociocultural and environmental factors. The relationship between home hazards and falls appears complex and deserves further evaluation. Geriatr Gerontol Int 2018; 18: 387-395. © 2017 Japan Geriatrics Society.

  17. Judicial Performance and Experiences of Judicial Work: Findings from Socio-legal Research

    Directory of Open Access Journals (Sweden)

    Sharyn Roach Anleu

    2014-12-01

    Full Text Available Judicial performance evaluation processes and programs tend to imply an abstract, normative model of the proper judge. The focus is on the individual judicial officer, identifying how judges ought to perform their judicial work and assessing any departures from the model. However, there is considerable diversity in judging which abstract models of JPE may not anticipate. Importantly, judicial performance occurs within a context – the practical and natural settings in which every day judicial work is undertaken. This entails time constraints, workload patterns, and dependence on the activities of others, factors over which the judicial officer may have little control, but which in turn may affect his/her behaviour. Often, judicial performance is taken to refer to in-court work only. Judicial work also occurs outside court and outside regular court hours and so may be less visible for judicial performance evaluation. Although there is considerable variety in judicial experiences of judging, JPE only sometimes includes self-perceptions or judges’ own reflections on their work. Social science and socio-legal research, including original empirical data from Australia, investigates judging in various contexts and explores judicial officers’ experiences of their work. Such empirical research can widen understandings of judicial performance and evaluation. Los procesos y programas de evaluación del rendimiento judicial tienden a implicar un modelo normativo abstracto del juez competente. La atención se centra en el funcionario judicial individual, identificando cómo deben realizar su labor los jueces y determinando cualquier desviación respecto al modelo. Sin embargo, a la hora de juzgar, existe una gran diversidad que los modelos abstractos de evaluación del rendimiento judicial no pueden anticipar. Es importante destacar que el desempeño judicial se produce en un contexto – el marco práctico y natural en el que se desarrolla cada d

  18. Witness for Wellness: preliminary findings from a community-academic participatory research mental health initiative.

    Science.gov (United States)

    Bluthenthal, Ricky N; Jones, Loretta; Fackler-Lowrie, Nicole; Ellison, Marcia; Booker, Theodore; Jones, Felica; McDaniel, Sharon; Moini, Moraya; Williams, Kamau R; Klap, Ruth; Koegel, Paul; Wells, Kenneth B

    2006-01-01

    Quality improvement programs promoting depression screening and appropriate treatment can significantly reduce racial and ethnic disparities in mental-health care and outcomes. However, promoting the adoption of quality-improvement strategies requires more than the simple knowledge of their potential benefits. To better understand depression issues in racial and ethnic minority communities and to discover, refine, and promote the adoption of evidence-based interventions in these communities, a collaborative academic-community participatory partnership was developed and introduced through a community-based depression conference. This partnership was based on the community-influenced model used by Healthy African-American Families, a community-based agency in south Los Angeles, and the Partners in Care model developed at the UCLA/RAND NIMH Health Services Research Center. The integrated model is described in this paper as well as the activities and preliminary results based on multimethod program evaluation techniques. We found that combining the two models was feasible. Significant improvements in depression identification, knowledge about treatment options, and availability of treatment providers were observed among conference participants. In addition, the conference reinforced in the participants the importance of community mobilization for addressing depression and mental health issues in the community. Although the project is relatively new and ongoing, already substantial gains in community activities in the area of depression have been observed. In addition, new applications of this integrated model are underway in the areas of diabetes and substance abuse. Continued monitoring of this project should help refine the model as well as assist in the identification of process and outcome measures for such efforts.

  19. Genomic research with human samples. Points of view from scientists and research subjects about disclosure of results and risks of genomic research. Ethical and empirical approach.

    Science.gov (United States)

    Valle Mansilla, José Ignacio

    2011-01-01

    Biomedical researchers often now ask subjects to donate samples to be deposited in biobanks. This is not only of interest to researchers, patients and society as a whole can benefit from the improvements in diagnosis, treatment, and prevention that the advent of genomic medicine portends. However, there is a growing debate regarding the social and ethical implications of creating biobanks and using stored human tissue samples for genomic research. Our aim was to identify factors related to both scientists and patients' preferences regarding the sort of information to convey to subjects about the results of the study and the risks related to genomic research. The method used was a survey addressed to 204 scientists and 279 donors from the U.S. and Spain. In this sample, researchers had already published genomic epidemiology studies; and research subjects had actually volunteered to donate a human sample for genomic research. Concerning the results, patients supported more frequently than scientists their right to know individual results from future genomic research. These differences were statistically significant after adjusting by the opportunity to receive genetic research results from the research they had previously participated and their perception of risks regarding genetic information compared to other clinical data. A slight majority of researchers supported informing participants about individual genomic results only if the reliability and clinical validity of the information had been established. Men were more likely than women to believe that patients should be informed of research results even if these conditions were not met. Also among patients, almost half of them would always prefer to be informed about individual results from future genomic research. The three main factors associated to a higher support of a non-limited access to individual results were: being from the US, having previously been offered individual information and considering

  20. A training programme to build cancer research capacity in low- and middle-income countries: findings from Guatemala.

    Science.gov (United States)

    Arnold, Lauren D; Barnoya, Joaquin; Gharzouzi, Eduardo N; Benson, Peter; Colditz, Graham A

    2014-04-01

    Guatemala is experiencing an increasing burden of cancer but lacks capacity for cancer prevention, control and research. In partnership with a medical school in the United States of America, a multidisciplinary Cancer Control Research Training Institute was developed at the Instituto de Cancerología (INCAN) in Guatemala City. This institute provided a year-long training programme for clinicians that focused on research methods in population health and sociocultural anthropology. The programme included didactic experiences in Guatemala and the United States as well as applied training in which participants developed research protocols responsive to Guatemala's cancer needs. Although INCAN is the point of referral and service for Guatemala's cancer patients, the institute's administration is also interested in increasing cancer research - with a focus on population health. INCAN is thus a resource for capacity building within the context of cancer prevention and control. Trainees increased their self-efficacy for the design and conduct of research. Value-added benefits included establishment of an annual cancer seminar and workshops in cancer pathology and qualitative analysis. INCAN has recently incorporated some of the programme's components into its residency training and established a research department. A training programme for clinicians can build cancer research capacity in low- and middle-income countries. Training in population-based research methods will enable countries such as Guatemala to gather country-specific data. Once collected, such data can be used to assess the burden of cancer-related disease, guide policy for reducing it and identify priority areas for cancer prevention and treatment.

  1. Increasing Capacity for Stewardship of Oceans and Coasts: Findings of the National Research Council Report

    Science.gov (United States)

    Roberts, S. J.; Feeley, M. H.

    2008-05-01

    With the increasing stress on ocean and coastal resources, ocean resource management will require greater capacity in terms of people, institutions, technology and tools. Successful capacity-building efforts address the needs of a specific locale or region and include plans to maintain and expand capacity after the project ends. In 2008, the US National Research Council published a report that assesses past and current capacity-building efforts to identify barriers to effective management of coastal and marine resources. The report recommends ways that governments and organizations can strengthen marine conservation and management capacity. Capacity building programs instill the tools, knowledge, skills, and attitudes that address: ecosystem function and change; processes of governance that influence societal and ecosystem change; and assembling and managing interdisciplinary teams. Programs require efforts beyond traditional sector-by-sector planning because marine ecosystems range from the open ocean to coastal waters and land use practices. Collaboration among sectors, scaling from local community-based management to international ocean policies, and ranging from inland to offshore areas, will be required to establish coordinated and efficient governance of ocean and coastal ecosystems. Barriers Most capacity building activities have been initiated to address particular issues such as overfishing or coral reef degradation, or they target a particular region or country facing threats to their marine resources. This fragmentation inhibits the sharing of information and experience and makes it more difficult to design and implement management approaches at appropriate scales. Additional barriers that have limited the effectiveness of capacity building programs include: lack of an adequate needs assessment prior to program design and implementation; exclusion of targeted populations in decision- making efforts; mismanagement, corruption, or both; incomplete or

  2. Landscape planning as a contribution to the assessment and finding of sites for energy facilities from an ecological and creative point of view

    International Nuclear Information System (INIS)

    Buchwald, K.

    1977-01-01

    The environmental agreeability examination through landscape planning in connection with the finding of sites for power stations and their integration into area planning is explained. The procedure of landscape planning for the assessment of power station sites is also presented. (RW) [de

  3. Putting Research Findings into Clinical Practice; Feasibility of integrated evidence-based care pathways in otorhinolaryngology head and neck surgery at Sultan Qaboos University Hospital, Oman

    Directory of Open Access Journals (Sweden)

    Deepa Bhargava

    2012-05-01

    Full Text Available Objectives: A perception exists that clinicians in Oman are reluctant to adopt evidence-based practice (EBP. This pilot study was undertaken to study the feasibility of using EBP pathways at the point of care in otorhinolaryngology head and neck surgery. The ultimate aim was to facilitate EBP with the probability of developing a new system for implementing research findings/translational research at the clinical point of care. Methods: A cross-sectional prospective questionnaire pilot survey of clinicians at Sultan Qaboos University Hospital (SQUH, Oman, a tertiary care medical centre, was undertaken. Respondents included 135 physicians and surgeons with between 3 months and 25 years of clinical experience and included personnel ranging from interns to senior consultants, in areas ranging from primary care to specialist care. Results: Of those polled, 90% (95% confidence interval (CI 85–95% either strongly agreed or agreed that evidence-based practice protocols (EBPP could help in decision making. A total of 87.4% of participants (95% CI 81.8–93% either strongly agreed or agreed that EBPPs can improve clinical outcomes; 91.8% of participants (95% CI 87.2–96.4% would use and apply EBPP in day-to-day care if they were available at the point of care and embedded in the hospital information system. Conclusions: The perception that clinicians at SQUH are reluctant to adopt EBP is incorrect. The introduction of EBP pathways is very feasible at the primary care level. Institutional support for embedding EBP in hospital information systems is needed as well as further outcome research to assess the improvement in quality of care.

  4. Service user involvement in research may lead to contrary rather than collaborative accounts: findings from a qualitative palliative care study.

    Science.gov (United States)

    Forbat, Liz; Hubbard, Gill

    2016-04-01

    The aim of this study was to explore what data emerge when former carergivers (co-researchers) are trained to interview current care-givers about their experiences. Despite a trend of involving service users in conducting research interviews, there have been few examinations of how and whether a common service user identity has an impact on the data generated. Four co-researchers were recruited, trained and supported to conduct qualitative interviews with 11 current carers of people receiving palliative services. Conversation analysis was used to examine the conversational characteristics of the research interviews. Data were collected in 2010-2011. Conversation analysis identified that interactional difficulties were evident across the data. When co-researchers talked about their own experiences as carers, interviewees frequently changed the topic of conversation, thereby closing-down opportunities for further disclosure or elaboration from the interviewee about the original topic. Conversation analysis identifies how caregiving identities are co-constructed and points where there is agreement and disagreement in the co-construction. © 2015 John Wiley & Sons Ltd.

  5. Exposure to point-of-sale displays and changes in susceptibility to smoking: findings from a cohort study of school students.

    Science.gov (United States)

    Bogdanovica, Ilze; Szatkowski, Lisa; McNeill, Ann; Spanopoulos, Dionysis; Britton, John

    2015-04-01

    To investigate the association between frequency of visiting shops and noticing of tobacco point-of-sale (PoS) displays and the development of susceptibility to smoking, or smoking uptake, in secondary school students. Two surveys of a school based cohort study carried out in 2011 and 2012. Nottinghamshire, UK. A total of 2270 children aged 11-16 years from eight schools in Nottinghamshire. We investigated changes in susceptibility to smoking and smoking status in relation to frequency of visiting shops and noticing PoS displays and number of tobacco brands recognized, controlling for a range of potential confounders. Susceptibility to smoking was defined using a set of three questions covering intentions to try smoking, to smoke within the next year and likelihood of smoking if a best friend offered a cigarette. For the analysis we used multinomial logistic regression. Among non-susceptible never smokers, noticing PoS displays more frequently was associated independently with an increased risk of becoming susceptible to smoking [adjusted relative risk ratio (RRR) = 1.74; 99% confidence interval (CI) = 1.13-2.69], but was not associated with smoking uptake. Recognizing a higher number of brands among non-susceptible never smokers doubled the risk of becoming susceptible to smoking and of becoming a smoker, but this did not have a significant effect on transition to smoking among susceptible never smokers. Frequency of noticing tobacco PoS displays was not associated significantly with smoking uptake among those who were susceptible never smokers at baseline. Noticing tobacco point-of-sale displays more often and recognizing a higher number of tobacco brands is associated with an increased risk of becoming susceptible to smoking among adolescents in the United Kingdom, and recognizing a higher number of brands is associated positively with an increased risk of smoking uptake. © 2014 Society for the Study of Addiction.

  6. Do Students Eventually Get to Publish their Research Findings? The Case of Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Research in Cameroon.

    Science.gov (United States)

    Munung, Ns; Vidal, L; Ouwe-Missi-Oukem-Boyer, O

    2014-05-01

    Scientific publication is commonly used to communicate research findings and in most academic/research settings, to evaluate the potential of a researcher and for recruitment and promotion. It has also been said that researchers have the duty to make public, the findings of their research. As a result, researchers are encouraged to share their research findings with the scientific world through peer review publications. In this study, we looked at the characteristics and publication rate of theses that documented studies on human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome in Cameroon. TO CHECK IF A THESIS RESULTED IN A PUBLICATION, WE SEARCHED: A database of publications on HIV in Cameroon, African Journals Online, PubMed and Google scholar. For each publication we recorded if the student was an author, the position of the student in the author listing, the journal and where the journal was indexed. We also looked at the impact factor of the journals. One hundred and thirty theses/dissertations were included in the study, 74.6% (97/130) were written as part of a medical degree (MD), 23.8% (31/130) a postgraduate (PG) degree and 1.5% (2/130) for a Doctorate/PhD. On a whole, 13.9% (18/130) of the theses resulted in at least one publication in a scientific journal with a total of 22 journal articles, giving a mean publication rate of 0.17 article/thesis, 86.4% (11/22) were indexed on PubMed, 9.1% (2/22) on African Journals Online and 4.6% (1/22) on Google scholar. One PG thesis led to two book chapters. The student was the first author in 22.7% (5/22) of the articles and not an author in 9.1% (2/22) of the articles. Student supervisor was an author in all the articles. This study reveals that most students in Cameroon failed to transform their theses/dissertations to scientific publications. This indicates an urgent need to sensitize students on the importance of presenting their research findings in scientific meetings and peer reviewed journals

  7. Impact of initial platelet count on baseline angiographic finding and end-points in ST-elevation myocardial infarction referred for primary percutaneous coronary intervention.

    Science.gov (United States)

    Kaplan, Sahin; Kaplan, Safiye Tuba; Kiris, Abdulkadir; Gedikli, Omer

    2014-01-01

    The baseline platelet count (BPC) in patients with acute ST elevation myocardial infarction (STEMI) may reflect the baseline anjiografic finding and may also predic long-term outcomes after primary percutaneous coronary intervention (PPCI). Available data for the value of BPC in patients with STEMI treated with PPCI are still questionable. Therefore, we sought to determine the prognostic value of BPC for baseline angiographic finding and the impact of BPC on clinical outcomes of patients treating with PPCI. Blood sample for BPC was obtained on admission in 140 consecutive patients undergoing PPCI. Patients were divided 2 groups that group-1 (104 patients): TIMI flow-grade 0 and group-2 (36 patients): TIMI flow-grade 1-3. Follow-up was performed at 1-9 months. Baseline demographics were comparable, but, BPC was significantly higher in group-1 comparing 2 (293.7±59.8x10(9)/L vs. 237.7±50.9x10(9)/L, pmeasuring of a BPC on admission may also provide further practical and therapeutic profits.

  8. Impact of Point-of-Sale Tobacco Display Bans in Thailand: Findings from the International Tobacco Control (ITC) Southeast Asia Survey.

    Science.gov (United States)

    Li, Lin; Borland, Ron; Yong, Hua-Hie; Sirirassamee, Buppha; Hamann, Stephen; Omar, Maizurah; Quah, Anne C K

    2015-08-13

    In September 2005 Thailand became the first Asian country to implement a complete ban on the display of cigarettes and other tobacco products at point-of-sale (POS). This paper examined the impact of the POS tobacco display ban in Thailand, with Malaysia (which did not impose bans) serving as a comparison. The data came from the International Tobacco Control Southeast Asia Survey (2005-2011), a prospective cohort survey designed to evaluate the psychosocial and behavioral impacts of tobacco control policies. Main measures included smokers' reported awareness of tobacco displays and advertising at POS. At the first post-ban survey wave over 90% of smokers in Thailand were aware of the display ban policy and supported it, and about three quarters thought the ban was effective. Noticing tobacco displays in stores was lowest (16.9%) at the first post-ban survey wave, but increased at later survey waves; however, the levels were consistently lower than those in Malaysia. Similarly, exposure to POS tobacco advertising was lower in Thailand. The display ban has reduced exposure to tobacco marketing at POS. The trend toward increased noticing is likely at least in part due to some increase in violations of the display bans and/or strategies to circumvent them.

  9. Impact of Point-of-Sale Tobacco Display Bans in Thailand: Findings from the International Tobacco Control (ITC Southeast Asia Survey

    Directory of Open Access Journals (Sweden)

    Lin Li

    2015-08-01

    Full Text Available In September 2005 Thailand became the first Asian country to implement a complete ban on the display of cigarettes and other tobacco products at point-of-sale (POS. This paper examined the impact of the POS tobacco display ban in Thailand, with Malaysia (which did not impose bans serving as a comparison. The data came from the International Tobacco Control Southeast Asia Survey (2005–2011, a prospective cohort survey designed to evaluate the psychosocial and behavioral impacts of tobacco control policies. Main measures included smokers’ reported awareness of tobacco displays and advertising at POS. At the first post-ban survey wave over 90% of smokers in Thailand were aware of the display ban policy and supported it, and about three quarters thought the ban was effective. Noticing tobacco displays in stores was lowest (16.9% at the first post-ban survey wave, but increased at later survey waves; however, the levels were consistently lower than those in Malaysia. Similarly, exposure to POS tobacco advertising was lower in Thailand. The display ban has reduced exposure to tobacco marketing at POS. The trend toward increased noticing is likely at least in part due to some increase in violations of the display bans and/or strategies to circumvent them.

  10. Support for removal of point-of-purchase tobacco advertising and displays: findings from the International Tobacco Control (ITC) Canada survey.

    Science.gov (United States)

    Brown, Abraham; Boudreau, Christian; Moodie, Crawford; Fong, Geoffrey T; Li, Grace Y; McNeill, Ann; Thompson, Mary E; Hassan, Louise M; Hyland, Andrew; Thrasher, James F; Yong, Hua-Hie; Borland, Ron; Hastings, Gerard; Hammond, David

    2012-11-01

    Although most countries now have at least some restrictions on tobacco marketing, the tobacco industry meet these restrictions by re-allocating expenditure to unregulated channels, such as at point-of-purchase. Longitudinal data from 10 Canadian provinces in the International Tobacco Control Survey was analysed to examine adult smokers' support for a ban on tobacco advertising and displays in stores and whether this support is associated with noticing either advertising or displays in stores, and quit intentions, over time. In total, there were 4580 respondents in wave 5 (October 2006 to February 2007), wave 6 (September 2007 to February 2008) and wave 7 (October 2008 to June 2009). The surveys were conducted before, during and in some cases after the implementation of display bans in most Canadian provinces and territories. Smokers in all provinces showed strong support for a ban on tobacco displays over the study period. Levels of support for an advertising and display ban were comparable between Canadian provinces over time, irrespective of whether they had been banned or not. Noticing tobacco displays and signs in-store was demonstrably less likely to predict support for display (OR=0.73, p=0.005) and advertising (OR=0.78, p=0.02) ban, respectively. Smokers intending to quit were more likely to support advertising and display bans over time. This study serves as a timely reminder that the implementation of tobacco control measures, such as the removal of tobacco displays, appear to sustain support among smokers, those most likely to oppose such measures.

  11. Disentangling the roles of point-of-sale ban, tobacco retailer density and proximity on cessation and relapse among a cohort of smokers: findings from ITC Canada Survey.

    Science.gov (United States)

    Fleischer, Nancy L; Lozano, Paula; Wu, Yun-Hsuan; Hardin, James W; Meng, Gang; Liese, Angela D; Fong, Geoffrey T; Thrasher, James F

    2018-03-08

    To examine how point-of-sale (POS) display bans, tobacco retailer density and tobacco retailer proximity were associated with smoking cessation and relapse in a cohort of smokers in Canada, where provincial POS bans were implemented differentially over time from 2004 to 2010. Data from the 2005 to 2011 administrations of the International Tobacco Control (ITC) Canada Survey, a nationally representative cohort of adult smokers, were linked via residential geocoding with tobacco retailer data to derive for each smoker a measure of retailer density and proximity. An indicator variable identified whether the smoker's province banned POS displays at the time of the interview. Outcomes included cessation for at least 1 month at follow-up among smokers from the previous wave and relapse at follow-up among smokers who had quit at the previous wave. Logistic generalised estimating equation models were used to determine the relationship between living in a province with a POS display ban, tobacco retailer density and tobacco retailer proximity with cessation (n=4388) and relapse (n=866). Provincial POS display bans were not associated with cessation. In adjusted models, POS display bans were associated with lower odds of relapse which strengthened after adjusting for retailer density and proximity, although results were not statistically significant (OR 0.66, 95% CI 0.41 to 1.07, p=0.089). Neither tobacco retailer density nor proximity was associated with cessation or relapse. Banning POS retail displays shows promise as an additional tool to prevent relapse, although these results need to be confirmed in larger longitudinal studies. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  12. Experience of adjunctive cannabis use for chronic non-cancer pain: findings from the Pain and Opioids IN Treatment (POINT) study.

    Science.gov (United States)

    Degenhardt, Louisa; Lintzeris, Nicholas; Campbell, Gabrielle; Bruno, Raimondo; Cohen, Milton; Farrell, Michael; Hall, Wayne D

    2015-02-01

    There is increasing debate about cannabis use for medical purposes, including for symptomatic treatment of chronic pain. We investigated patterns and correlates of cannabis use in a large community sample of people who had been prescribed opioids for chronic non-cancer pain. The POINT study included 1514 people in Australia who had been prescribed pharmaceutical opioids for chronic non-cancer pain. Data on cannabis use, ICD-10 cannabis use disorder and cannabis use for pain were collected. We explored associations between demographic, pain and other patient characteristics and cannabis use for pain. One in six (16%) had used cannabis for pain relief, 6% in the previous month. A quarter reported that they would use it for pain relief if they had access. Those using cannabis for pain on average were younger, reported greater pain severity, greater interference from and poorer coping with pain, and more days out of role in the past year. They had been prescribed opioids for longer, were on higher opioid doses, and were more likely to be non-adherent with their opioid use. Those using cannabis for pain had higher pain interference after controlling for reported pain severity. Almost half (43%) of the sample had ever used cannabis for recreational purposes, and 12% of the entire cohort met criteria for an ICD-10 cannabis use disorder. Cannabis use for pain relief purposes appears common among people living with chronic non-cancer pain, and users report greater pain relief in combination with opioids than when opioids are used alone. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  13. Support for removal of point-of-purchase tobacco advertising and displays: findings from the International Tobacco Control (ITC) Canada survey

    Science.gov (United States)

    Brown, Abraham; Boudreau, Christian; Moodie, Crawford; Fong, Geoffrey T; Li, Grace Y; McNeill, Ann; Thompson, Mary E; Hassan, Louise M; Hyland, Andrew; Thrasher, James F; Yong, Hua-Hie; Borland, Ron; Hastings, Gerard; Hammond, David

    2013-01-01

    Background Although most countries now have at least some restrictions on tobacco marketing, the tobacco industry meet these restrictions by re-allocating expenditure to unregulated channels, such as at point-of-purchase. Methods Longitudinal data from 10 Canadian provinces in the International Tobacco Control Survey was analysed to examine adult smokers’ support for a ban on tobacco advertising and displays in stores and whether this support is associated with noticing either advertising or displays in stores, and quit intentions, over time. In total, there were 4580 respondents in wave 5 (October 2006 to February 2007), wave 6 (September 2007 to February 2008) and wave 7 (October 2008 to June 2009). The surveys were conducted before, during and in some cases after the implementation of display bans in most Canadian provinces and territories. Results Smokers in all provinces showed strong support for a ban on tobacco displays over the study period. Levels of support for an advertising and display ban were comparable between Canadian provinces over time, irrespective of whether they had been banned or not. Noticing tobacco displays and signs in-store was demonstrably less likely to predict support for displays (OR=0.73, p=0.005) and advertising (OR=0.78, p=0.02) ban, respectively. Smokers intending to quit were more likely to support advertising and display bans over time. Conclusion This study serves as a timely reminder that the implementation of tobacco control measures, such as the removal of tobacco displays, appear to sustain support among smokers, those most likely to oppose such measures. PMID:23076786

  14. The ROOTS study: a 10-year review of findings on adolescent depression, and recommendations for future longitudinal research.

    Science.gov (United States)

    Lewis, Gemma; Jones, Peter B; Goodyer, Ian M

    2016-02-01

    The purpose of this study is to review longitudinal findings on adolescent mental health from the 'ROOTS study', and provide directions and recommendations for future longitudinal research. To do this, we discuss relevant findings from the ROOTS study, and review its strengths and limitations. We examined all publications from the ROOTS study up to July 2015, selected those examining adolescent mental health, and classified them as investigating (a) childhood risk factors for adolescent depression, (b) genetic and cognitive vulnerability to depression in adolescence, (c) genetic markers, childhood adversities, and neuroendophenotypes, (d) morning cortisol and depression, (e) physical activity and depression symptoms, and (f) the underlying structure of mental health in adolescence. We reviewed the strengths and limitations of the ROOTS study, and how they feed into recommendations for future longitudinal research. There was evidence supporting a putative hormonal biomarker for the emergence of depression in boys. Environmental pathways from child adversity to adolescent depression were confirmed in girls, partly accounted for by negative life events in early adolescence. The preceding role of automatic cognitive biases assessed using behavioural tasks was substantiated, with evidence for genetic susceptibility. Novel latent statistical models of child adversity, depression, anxiety, and psychotic experiences were produced, with concurrent and prospective validity. Our experiences conducting the ROOTS study resulted in a set of strengths, limitations, and recommendations for future longitudinal studies. The ROOTS study has advanced knowledge on the aetiology of adolescent depression by investigating environmental, genetic, hormonal, and neural risk factors. Findings provide a foundation for future research integrating cognitive neuroscience with epidemiology.

  15. Radical university-industry innovation – research design and preliminary findings from an on-going qualitative case study

    DEFF Research Database (Denmark)

    Gertsen, Frank; Nielsen, René Nesgaard

    and it is arguing that there is a lack of in-depth understanding of such collaborative radical innovation processes. The paper then suggests an abductive research design for an explorative in-depth case study of collaborative radical innovation involving a university and an established Danish manufacturing firm....... Some preliminary findings are presented and briefly discussed, including the role of the university’s formal set-up to deal with IPR/commercialisation and the researchers’ personal networking with industry as well as challenges concerning the sharing of IPR/commercialisation outcomes....

  16. Tipping Points and Balancing Acts: Grand Challenges and Synergistic Opportunities of Integrating Research and Education, Science and Solutions

    Science.gov (United States)

    McCaffrey, M. S.; Stroeve, J. C.

    2011-12-01

    thousands of US high schools that integrate climate science and solutions in a way that inspires and informs youth, and similar programs exist internationally. Other approaches to prepare vulnerable communities, especially young people, for natural hazards and human-induced environmental change include programs such as Plan International's "Child Centered Disaster Risk Reduction- Building Resilience Through Participation," and their "Weathering the Storm" project, focusing on integrating the needs of teenage girls with climate change adaptation and risk reduction. While minimizing global environmental and climate change is crucial, these and related programs that weave research with education, science with solutions offer the potential for addressing the "Grand Challenges" by better preparing for societal and environmental tipping points through a more balanced and integrated approach to addressing change."

  17. Informed consent instead of assent is appropriate in children from the age of twelve: Policy implications of new findings on children's competence to consent to clinical research.

    Science.gov (United States)

    Hein, Irma M; De Vries, Martine C; Troost, Pieter W; Meynen, Gerben; Van Goudoever, Johannes B; Lindauer, Ramón J L

    2015-11-09

    For many decades, the debate on children's competence to give informed consent in medical settings concentrated on ethical and legal aspects, with little empirical underpinnings. Recently, data from empirical research became available to advance the discussion. It was shown that children's competence to consent to clinical research could be accurately assessed by the modified MacArthur Competence Assessment Tool for Clinical Research. Age limits for children to be deemed competent to decide on research participation have been studied: generally children of 11.2 years and above were decision-making competent, while children of 9.6 years and younger were not. Age was pointed out to be the key determining factor in children's competence. In this article we reflect on policy implications of these findings, considering legal, ethical, developmental and clinical perspectives. Although assessment of children's competence has a normative character, ethics, law and clinical practice can benefit from research data. The findings may help to do justice to the capacities children possess and challenges they may face when deciding about treatment and research options. We discuss advantages and drawbacks of standardized competence assessment in children on a case-by-case basis compared to application of a fixed age limit, and conclude that a selective implementation of case-by-case competence assessment in specific populations is preferable. We recommend the implementation of age limits based on empirical evidence. Furthermore, we elaborate on a suitable model for informed consent involving children and parents that would do justice to developmental aspects of children and the specific characteristics of the parent-child dyad. Previous research outcomes showed that children's medical decision-making capacities could be operationalized into a standardized assessment instrument. Recommendations for policies include a dual consent procedure, including both child as well as parents

  18. Finding and engaging patients and the public to work collaboratively on an acute infection microbiology research public panel.

    Science.gov (United States)

    Grier, Sally; Evans, David; Gibson, Andy; Chin, Teh Li; Stoddart, Margaret; Kok, Michele; Campbell, Richard; Kenny, Val; MacGowan, Alasdair

    2018-01-01

    In 2015 a microbiology team in Bristol joined a European research project that aims to develop new antibiotics to fight drug resistant infections. The microbiology team were convinced of the benefits of patient and public involvement, but had found it difficult to find former patients to work with on earlier microbiology research. This paper describes how the team overcame this challenge to successfully recruit a PPI panel to develop PPI within the European project.The advice from people with experience in public involvement was to decide what criteria were desirable for panel membership, think about what the work of the panel might involve and how long the project will go on. The team decided that experience of suffering a serious acute infection would qualify people to comment on this project. Next, the team needed to identify ways of finding people to join the PPI panel.The microbiology research team tried different ways to approach potential panel members. These included distributing flyers at public research events, sending emails to potentially interested people, posting a message on the hospital Facebook page and approaching eligible people known to the team. A direct approach was the most successful method - either by email, mail or in person. Ultimately 16 people were selected to form the panel. Key factors for success were planning what the work of the panel might be, perseverance despite early lack of success, and one person having overall responsibility for setting up the panel, with the support of the whole team. Background In 2015 the microbiology research team became involved in a large European programme of research aiming to bring new antimicrobial drugs onto the market to combat the increasing problem of multi-drug resistant infection. With the purpose of developing patient and public involvement (PPI) in this project, the team decided to recruit a PPI panel to work with. The microbiology team had previously worked with a PPI panel on other

  19. The financial management of research centers and institutes at U.S. medical schools: findings from six institutions.

    Science.gov (United States)

    Mallon, William T

    2006-06-01

    To explore three questions surrounding the financial management of research centers and institutes at U.S. medical schools: How do medical schools allocate institutional funds to centers and institutes? How and by whom are those decisions made? What are the implications of these decision-making models on the future of the academic biomedical research enterprise? Using a qualitative research design, the author and associates interviewed over 150 faculty members and administrators at six medical schools and their parent universities in 2004. Interview data were transcribed, coded, and analyzed using a grounded theory approach. This methodology generated rich descriptions and explanations of the six medical schools, which can produce extrapolations to, but not necessarily generalizable findings to, other institutions and settings. An examination of four dimensions of financial decision-making-funding timing, process, structure, and culture-produces two essential models of how medical schools approach the financial management of research centers. In the first, a "charity" model, center directors make hat-in-hand appeals directly to the dean, the result of which may depend on individual negotiation skills and personal relationships. In the second, a "planned-giving" model, the process for obtaining and renewing funds is institutionalized, agreed upon, and monitored. The ways in which deans, administrators, department chairs, and center directors attend to, decide upon, and carry out financial decisions can influence how people throughout the medical school think about interdisciplinary and collaborative activities marshalled though centers and institutes.

  20. The relevance of large scale environmental research infrastructures from the point of view of Ethics: the case of EMSO

    Science.gov (United States)

    Favali, Paolo; Beranzoli, Laura; Best, Mairi; Franceschini, PierLuigi; Materia, Paola; Peppoloni, Silvia; Picard, John

    2014-05-01

    instability and failure; • connecting scientific outcomes to stakeholders and policy makers, including to government decision-makers. The development of a large research infrastructure initiatives like EMSO must continuously take into account wide-reaching environmental and socio-economic implications and objectives. For this reason, an Ethics Commitee was established early in EMSO's initial Preparatory Phase with responsibility for overseeing the key ethical and social aspects of the project. These include: • promoting inclusive science communication and data dissemination services to civil society according to Open Access principles; • guaranteeing top quality scientific information and data as results of top quality research; • promoting the increased adoption of eco-friendly, sustainable technologies through the dissemination of advanced scientific knowledge and best practices to the private sector and to policy makers; • developing Education Strategies in cooperation with academia and industry aimed at informing and sensitizing the general public on the environmental and socio-economic implications and benefits of large research infrastructure initiatives such as EMSO; • carrying out Excellent Science following strict criteria of research integrity, as expressed in the Montreal Statement (2013); • promoting Geo-ethical awareness and innovation by spurring innovative approaches in the management of environmental aspects of large research projects; • supporting technological Innovation by working closely in support of SMEs; • providing a constant, qualified and authoritative one-stop-shopping Reference Point and Advisory for politicians and decision-makers. The paper shows how Geoethics is an essential tool for guiding methodological and operational choices, and management of an European project with great impact on the environment and society.

  1. Point Source contamination approach for hydrological risk assessment of a major hypothetical accident from second research reactor at Inshas site

    International Nuclear Information System (INIS)

    Sadek, M.A.; Tawfik, F.S.

    2002-01-01

    The point source contamination mechanism and the deterministic conservative approach have been implemented to demonstrate the hazards of hydrological pollution due to a major hypothetical accident in the second research reactor at Inshas. The radioactive inventory is assumed to be dissolved in 75% of the cooling water (25% are lost) and comes directly into contact with ground water and moved down gradient. Five radioisotopes(I-129, Sr-90, Ru-106, Cs-134 and Cs-137) of the entire inventory are found to be highly durable and represent vulnerability in the environment. Their downstream spread indices; C max : maximum concentration at the focus of the moving ellipse, delta: pollution duration at different distances, A:polluted area at different distances and X min : safety distance from the reactor, were calculated based on analytical solutions of the convection-dispersion partial differential equation for absorbable and decaying species. The largest downstream contamination range was found for Sr-90 and Ru-106 but still no potential. The geochemical and hydrological parameters of the water bearing formations play a great role in buffering and limiting the radiation effects. These reduce the retention time of the radioisotopes several order of magnitudes in the polluted distances. Sensitivity analysis of the computed pollution ranges shows low sensitivity to possible potential for variations activity of nuclide inventory, dispersivity and saturated thickness and high sensitivity for possible variations in groundwater velocity and retention factors

  2. Cyberbullying as a negative result of cyber-culture of Slovak children and adolescents: selected research findings

    Directory of Open Access Journals (Sweden)

    Hollá Katarína

    2016-05-01

    Full Text Available Cyber-culture points out the life in cyberspace and goes beyond national cultures. It is particularly attractive for the young people who use Information and Communications Technologies (ICT to express their attitudes, values, beliefs and thinking. Those do not need to be necessarily in accordance with the standards of an individual society. Cyberculture becomes dangerous. Great risk lies in cyberbullying that represents negative impact of cyber-culture on human behavior. The aim of the study is to detect cyberbullying as a negative impact of cyber-culture among of Slovak children and adolescents. The research was carried out on a sample of 1619 11-18-year old respondents (average age was 14.51. Results of cyberbullying research carried out using Latent Class Analysis (LCA have proved the appropriateness of 3-latent-class module. Relative entropy of the module reached 0.915. It was demonstrated that 52.9% of respondents belonged to the group of uninvolved, 42.7% were victims and 4.4% were victims-aggressors. Being a negative consequence of cyber-culture, cyberbullying is a challenge that educators - including other assisting professions - face when educating children and adolescents to orientate in cyberspace, behave responsibly, express themselves in a way that would not interfere others’ integrity and identity (personal and virtual. The study was written under VEGA MŠVVaŠ SR a SAV č. 1/0244/15: “Detekcia a riešenie kyberšikany”.

  3. Cognitive Biases in Children and Adolescents With Chronic Pain: A Review of Findings and a Call for Developmental Research.

    Science.gov (United States)

    Lau, Jennifer Y F; Heathcote, Lauren C; Beale, Sarah; Gray, Suzy; Jacobs, Konrad; Wilkinson, Nick; Crombez, Geert

    2018-06-01

    Cognitive biases that emphasize bodily harm, injury, and illness could play a role in the maintenance of chronic pain by facilitating fear and avoidance. Whereas extensive research has established attention, interpretation, and memory biases in adults with chronic pain, far less is known about these same biases in children and adolescents with pain. Studying cognitive biases in attention, interpretation, and memory in relation to pain occurring in youth is important because youth is a time when pain can first become chronic, and when relationships between cognitive biases and pain outcomes emerge and stabilize. Thus, youth potentially offers a time window for the prevention of chronic pain problems. In this article, we summarize the growing corpus of data that have measured cognitive biases in relation to pediatric pain. We conclude that although biases in attention, interpretation, and memory characterize children and adolescents with varying pain experiences, questions regarding the direction, magnitude, nature, and role of these biases remain. We call for independent extension of cognitive bias research in children and adolescents, using well powered longitudinal studies with wide age ranges and psychometrically sound experimental measures to clarify these findings and any developmental trends in the links between cognitive biases and pain outcomes. This article provides a rationale for the theoretical and practical importance of studying the role of cognitive biases in children and adolescents with chronic pain, which has to date, been relatively understudied. Existing findings are reviewed critically, and recommendations for future research are offered. Copyright © 2018 The American Pain Society. Published by Elsevier Inc. All rights reserved.

  4. Scientific findings of Alexander von Humboldt's expedition into the Spanish-American Tropics (1799-1804 from a geographical point of view

    Directory of Open Access Journals (Sweden)

    Gerd Kohlhepp

    2005-06-01

    Full Text Available Alexander von Humboldt's expedition from 1799 till 1804 to the "equinoctial regions of the new world" led through Venezuela, Cuba, Colombia, Ecuador, Peru, and Mexico. In Europe an increased knowledge of the "New World" was connected with the privately funded journey, which served purely scientific purposes and had nothing to do with the exploration and exploitation of natural resources. Besides the research results, which were based on new measuring methods and the quantitative ascertainment of scientific basics, the journey also made possible detailed descriptions in matters of regional studies including social, socio-economic, political, and economic-geographic circumstances, which were based on empirical field studies. The expedition took place shortly before the political change in Latin America. Humboldt, who still experienced the feudal character of global economy based on slave labor in the colonies, vehemently criticized this economic structure - although he was a noble - and its unbearable social conditions. This is the reason why Humboldt is still admired in Latin America till this day. In Europe the scientific insights of his journey to the tropics and his innovative impulses in geog raphy as well as in many other disciplines brought him fame and lasting recognition as a universal scholar, who had crucial influence on the development of the sciences during the first half of the 19th century.A expedição científica de Alexander von Humboldt de 1799 a 1804 pela região equinocial do novo mundo foi realizada através dos países Venezuela, Cuba, Colômbia, Equador, Peru e México. Esta viagem, destinada à obtenção de novos conhecimentos aprofundados sobre o "novo mundo" para a Europa, foi financiada com meios particulares e tinha exclusivamente objetivos científicos e não a exploração de recursos naturais. Paralelamente aos resultados de pesquisa, fundamentados em novos métodos de medida e da elaboração quantitativa de

  5. Lessons for tsunami risk mitigation from recent events occured in Chile: research findings for alerting and evacuation from interdisciplinary perspectives

    Science.gov (United States)

    Cienfuegos, R.; Catalan, P. A.; Leon, J.; Gonzalez, G.; Repetto, P.; Urrutia, A.; Tomita, T.; Orellana, V.

    2016-12-01

    In the wake of the 2010 tsunami that hit Chile, a major public effort to promote interdisciplinary disaster reseach was undertaken by the Comisión Nacional de Investigación Científica y Tecnológica (Conicyt) allocating funds to create the Center for Integrated Research on Natural Risks Management (CIGIDEN). This effort has been key in promoting associativity between national and international research teams in order to transform the frequent occurrence of extreme events that affect Chile into an opportunity for interdisciplinary research. In this presentation we will summarize some of the fundamental research findings regarding tsunami forecasting, alerting, and evacuation processes based on interdisciplinary field work campaigns and modeling efforts conducted in the wake of the three most recent destructive events that hit Chile in 2010, 2014, and 2015. One of the main results that we shall emphatize from these findings, is that while research and operational efforts to model and forecast tsunamis are important, technological positivisms should not undermine educational efforts that have proved to be effective in reducing casualties due to tsunamis in the near field. Indeed, in recent events that hit Chile, first tsunami waves reached the adjacent generation zones in time scales comparable with the required time for data gathering and modeling even for the most sophisticated early warning tsunami algorithms currently available. The latter emphasizes self-evacuation from coastal areas, while forecasting and monitoring tsunami hazards remain very important for alerting more distant areas, and are essential for alert cancelling especially when shelf and embayment resonance, and edge wave propagation may produce destructive late tsunami arrivals several hours after the nucleation of the earthquake. By combining some of the recent evidence we have gathered in Chile on seismic source uncertainities (both epistemic and aleatoric), tsunami hydrodynamics, the response

  6. Climate change and human infectious diseases: A synthesis of research findings from global and spatio-temporal perspectives.

    Science.gov (United States)

    Liang, Lu; Gong, Peng

    2017-06-01

    The life cycles and transmission of most infectious agents are inextricably linked with climate. In spite of a growing level of interest and progress in determining climate change effects on infectious disease, the debate on the potential health outcomes remains polarizing, which is partly attributable to the varying effects of climate change, different types of pathogen-host systems, and spatio-temporal scales. We summarize the published evidence and show that over the past few decades, the reported negative or uncertain responses of infectious diseases to climate change has been growing. A feature of the research tendency is the focus on temperature and insect-borne diseases at the local and decadal scale. Geographically, regions experiencing higher temperature anomalies have been given more research attention; unfortunately, the Earth's most vulnerable regions to climate variability and extreme events have been less studied. From local to global scales, agreements on the response of infectious diseases to climate change tend to converge. So far, an abundance of findings have been based on statistical methods, with the number of mechanistic studies slowly growing. Research gaps and trends identified in this study should be addressed in the future. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  7. FIRST AND SECOND LANGUAGE DEVELOPMENT IN YOUNG CHILDREN AND BILINGUALISM IN LIGHT OF LINGUISTICS, NEUROLINGUISTICS AND FINDINGS FROM BRAIN RESEARCH

    Directory of Open Access Journals (Sweden)

    Yunus PINAR

    2015-10-01

    Full Text Available The present review shows that infants begin picking up elements of what will be their first language in the womb, and certainly long before their first coo according to the current guidelines and it presents a descriptive approach to bilingualism and multilingualism. This article is the outcome of a thorough survey of literature and primarily it aims to present the similarities and differences between the L1 and L2 acquisition in light of linguistics, neurolinguistics and findings from brain research. This Review will illustrate various thought and new hypotheses on first and second language development, bilingualism and multilingualism derived from studies in linguistics, neurolinguistics and brain research. In the context of our paper we shall try to describe aspects and stages of first language acquisition from even before birth especially the 20th week of the fetal development of the baby to 60th week of life, as well as the second language acquisition process, which is divided into three types: simultaneous, consecutive and adult. In particular, we will present and discuss some of the main results of the brain researchers like Franceschini and De Bleser and we shall interpret them.

  8. The impact on healthcare, policy and practice from 36 multi-project research programmes: findings from two reviews.

    Science.gov (United States)

    Hanney, Steve; Greenhalgh, Trisha; Blatch-Jones, Amanda; Glover, Matthew; Raftery, James

    2017-03-28

    We sought to analyse the impacts found, and the methods used, in a series of assessments of programmes and portfolios of health research consisting of multiple projects. We analysed a sample of 36 impact studies of multi-project research programmes, selected from a wider sample of impact studies included in two narrative systematic reviews published in 2007 and 2016. We included impact studies in which the individual projects in a programme had been assessed for wider impact, especially on policy or practice, and where findings had been described in such a way that allowed them to be collated and compared. Included programmes were highly diverse in terms of location (11 different countries plus two multi-country ones), number of component projects (8 to 178), nature of the programme, research field, mode of funding, time between completion and impact assessment, methods used to assess impact, and level of impact identified. Thirty-one studies reported on policy impact, 17 on clinician behaviour or informing clinical practice, three on a combined category such as policy and clinician impact, and 12 on wider elements of impact (health gain, patient benefit, improved care or other benefits to the healthcare system). In those multi-programme projects that assessed the respective categories, the percentage of projects that reported some impact was policy 35% (range 5-100%), practice 32% (10-69%), combined category 64% (60-67%), and health gain/health services 27% (6-48%). Variations in levels of impact achieved partly reflected differences in the types of programme, levels of collaboration with users, and methods and timing of impact assessment. Most commonly, principal investigators were surveyed; some studies involved desk research and some interviews with investigators and/or stakeholders. Most studies used a conceptual framework such as the Payback Framework. One study attempted to assess the monetary value of a research programme's health gain. The widespread

  9. Use of portable blood physiology point-of-care devices for basic and applied research on vertebrates: a review.

    Science.gov (United States)

    Stoot, Lauren J; Cairns, Nicholas A; Cull, Felicia; Taylor, Jessica J; Jeffrey, Jennifer D; Morin, Félix; Mandelman, John W; Clark, Timothy D; Cooke, Steven J

    2014-01-01

    Non-human vertebrate blood is commonly collected and assayed for a variety of applications, including veterinary diagnostics and physiological research. Small, often non-lethal samples enable the assessment and monitoring of the physiological state and health of the individual. Traditionally, studies that rely on blood physiology have focused on captive animals or, in studies conducted in remote settings, have required the preservation and transport of samples for later analysis. In either situation, large, laboratory-bound equipment and traditional assays and analytical protocols are required. The use of point-of-care (POC) devices to measure various secondary blood physiological parameters, such as metabolites, blood gases and ions, has become increasingly popular recently, due to immediate results and their portability, which allows the freedom to study organisms in the wild. Here, we review the current uses of POC devices and their applicability to basic and applied studies on a variety of non-domesticated species. We located 79 individual studies that focused on non-domesticated vertebrates, including validation and application of POC tools. Studies focused on a wide spectrum of taxa, including mammals, birds and herptiles, although the majority of studies focused on fish, and typical variables measured included blood glucose, lactate and pH. We found that calibrations for species-specific blood physiology values are necessary, because ranges can vary within and among taxa and are sometimes outside the measurable range of the devices. In addition, although POC devices are portable and robust, most require durable cases, they are seldom waterproof/water-resistant, and factors such as humidity and temperature can affect the performance of the device. Overall, most studies concluded that POC devices are suitable alternatives to traditional laboratory devices and eliminate the need for transport of samples; however, there is a need for greater emphasis on rigorous

  10. Using Research Case Studies in eCommerce Marketing Courses: Customer Satisfaction at Point-of-Purchase and Post-Purchase

    Science.gov (United States)

    Nawi, Noorshella Che; Fong, Michelle; Tatnall, Arthur

    2014-01-01

    This paper describes a research case study of Internet apparel marketing by small businesses in Malaysia which can beneficially be included in postgraduate business courses for understanding the importance of measuring customer satisfaction at point-of-purchase and post-purchase in online purchases. The sample size in this research is 154…

  11. Behaviour change strategies for reducing blood pressure-related disease burden: findings from a global implementation research programme.

    Science.gov (United States)

    Peiris, David; Thompson, Simon R; Beratarrechea, Andrea; Cárdenas, María Kathia; Diez-Canseco, Francisco; Goudge, Jane; Gyamfi, Joyce; Kamano, Jemima Hoine; Irazola, Vilma; Johnson, Claire; Kengne, Andre P; Keat, Ng Kien; Miranda, J Jaime; Mohan, Sailesh; Mukasa, Barbara; Ng, Eleanor; Nieuwlaat, Robby; Ogedegbe, Olugbenga; Ovbiagele, Bruce; Plange-Rhule, Jacob; Praveen, Devarsetty; Salam, Abdul; Thorogood, Margaret; Thrift, Amanda G; Vedanthan, Rajesh; Waddy, Salina P; Webster, Jacqui; Webster, Ruth; Yeates, Karen; Yusoff, Khalid

    2015-11-09

    . The findings highlight the importance of contextual factors in driving success and failure of research programmes. Forthcoming outcome and process evaluations from each project will build on this exploratory work and provide a greater understanding of factors that might influence scale-up of intervention strategies.

  12. [Great discoveries: from the painstaking efforts of researchers to the contribution of accidental findings and the dissemination of study results].

    Science.gov (United States)

    Garattini, Silvio

    2015-06-01

    This article takes its cue from the original work of sir Alexander Fleming on penicillin, published in the first issue of Recenti Progressi in Medicina in 1946 and reproduced here on the occasion of the approaching 70-year anniversary of the journal. The path that brought Fleming to the discovery of penicillin, one of the major milestones in the history of clinical pharmacology, provides insight for a range of considerations: the painstaking efforts of researchers, the contribution from accidental findings, and the dissemination of study results. Although the discovery of penicillin has changed the course of medicine, the benefits deriving from such an important advance are most likely to be offset by the overprescription of antibiotics, which is the leading cause of antimicrobial resistance and one of the most serious public health problems of our time.

  13. Adolescent perceptions of violence: formative research findings from a social marketing campaign to reduce violence among middle school youth.

    Science.gov (United States)

    Quinn, G P; Bell-Ellison, B A; Loomis, W; Tucci, M

    2007-05-01

    To identify the specific barriers and benefits of violent behaviours as noted by middle school youth and to develop a social marketing campaign that attends to the needs and wants of the target audience. A non-experimental, qualitative study design was used to assess youth perceptions of violence in a large, southeast urban school district. Using a social marketing approach, a series of in-depth interviews were conducted with middle school youths, to gain an understanding of perceived barriers and benefits of violent behaviours. Additionally, interviews assessed youth preferences for an effective spokesperson for an anti-violence campaign. Qualitative analysis of coded transcripts revealed key themes that were incorporated into a multi-media initiative. Critical themes of the research highlighted that the majority of violence occurs at school, during school hours and most of the youths believed the use of violence was necessary to defend themselves from other peers or to protect family members. Another key finding pertained to adolescent views on violent people; although the majority of respondents reported engaging in violent acts, they did not view themselves as violent. Results were used to inform the development of a social marketing campaign designed to reduce youth violence among middle school students in a large, urban central Florida school district. Findings from the formative research led to the creation and pre-testing of five potential campaign brands. The campaign slogan that tested best with the target audience emphasized the choice youth have to either engage in violent behaviour and suffer the consequences or to 'rise above' physical conflict and reap the benefits.

  14. Characterizing fixed points

    Directory of Open Access Journals (Sweden)

    Sanjo Zlobec

    2017-04-01

    Full Text Available A set of sufficient conditions which guarantee the existence of a point x⋆ such that f(x⋆ = x⋆ is called a "fixed point theorem". Many such theorems are named after well-known mathematicians and economists. Fixed point theorems are among most useful ones in applied mathematics, especially in economics and game theory. Particularly important theorem in these areas is Kakutani's fixed point theorem which ensures existence of fixed point for point-to-set mappings, e.g., [2, 3, 4]. John Nash developed and applied Kakutani's ideas to prove the existence of (what became known as "Nash equilibrium" for finite games with mixed strategies for any number of players. This work earned him a Nobel Prize in Economics that he shared with two mathematicians. Nash's life was dramatized in the movie "Beautiful Mind" in 2001. In this paper, we approach the system f(x = x differently. Instead of studying existence of its solutions our objective is to determine conditions which are both necessary and sufficient that an arbitrary point x⋆ is a fixed point, i.e., that it satisfies f(x⋆ = x⋆. The existence of solutions for continuous function f of the single variable is easy to establish using the Intermediate Value Theorem of Calculus. However, characterizing fixed points x⋆, i.e., providing answers to the question of finding both necessary and sufficient conditions for an arbitrary given x⋆ to satisfy f(x⋆ = x⋆, is not simple even for functions of the single variable. It is possible that constructive answers do not exist. Our objective is to find them. Our work may require some less familiar tools. One of these might be the "quadratic envelope characterization of zero-derivative point" recalled in the next section. The results are taken from the author's current research project "Studying the Essence of Fixed Points". They are believed to be original. The author has received several feedbacks on the preliminary report and on parts of the project

  15. Finding people who will tell you their thoughts on genomics-recruitment strategies for social sciences research.

    Science.gov (United States)

    Middleton, A; Bragin, E; Parker, M

    2014-10-01

    This paper offers a description of how social media, traditional media and direct invitation were used as tools for the recruitment of 6,944 research participants for a social sciences study on genomics. The remit was to gather the views of various stakeholders towards sharing incidental findings from whole genome studies. This involved recruiting members of the public, genetic health professionals, genomic researchers and non-genetic health professionals. A novel survey was designed that contained ten integrated films; this was made available online and open for completion by anyone worldwide. The recruitment methods are described together with the convenience and snowballing sampling framework. The most successful strategy involved the utilisation of social media; Facebook, Blogging, Twitter, LinkedIn and Google Ads led to the ascertainment of over 75 % of the final sample. We conclude that the strategies used were successful in recruiting in eclectic mix of appropriate participants. Design of the survey and results from the study are presented separately.

  16. RESEARCH OF APPROACHES TO INCREASE THE EFFICIENCY OF FUNCTIONING OF RAILWAY TRANSPORT SUBDIVISIONS FROM THE POINT OF VIEW OF SUSTAINABLE DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    O. I. Kharchenko

    2014-07-01

    Full Text Available Purpose. Modern transport systems are not stable and can not stand up to the destabilizing factors. Global track record in the economic and commercial management systems is the use of the concept of sustainable development. It is necessary on the basis of analysis of literary sources to define the directions of efficiency increase of functioning of railway transport subdivisions from the point of view of sustainable development. Methodology. To achieve the purpose the features of the use of sustainable development conception and its realization were investigated at a management of the complex systems. The existent models were also analyzed in the field of efficiency increase of functioning of railway transport subdivisions. Findings. On the basis of literary sources analysis, keeping up the conceptual essence of the sustainable development, the main directions of efficiency increase of subdivisions functioning were selected. They take into account the basic requirements of steady development and should be considered as a complex. Originality. New directions to consider the efficiency increase issues from position of sustainable development were offered by the author. Three components of conceptions of sustainable development (economic, ecological and social should be examined in a balanced way. Thus, the above mentioned theoretical studies can promote the forming of new economy model corresponding to the purposes and principles of sustainable development. Practical value. The conducted analysis development confirms the necessity of researches on perspective directions of development of railway transport subdivisions, which are marked by the guidance of Ukrzaliznytsia. It enables to select basic directions for further research in the area of efficiency increase.

  17. The impact of sleep disorders on driving safety-findings from the Second Strategic Highway Research Program naturalistic driving study.

    Science.gov (United States)

    Liu, Shu-Yuan; Perez, Miguel A; Lau, Nathan

    2018-04-01

    This study investigated the association between driving safety and seven sleep disorders amongst 3541 participants of the Second Strategic Highway Research Program (SHRP 2) naturalistic driving study. SHRP 2 collected naturalistic driving data from participants between 16 and 98 years old by instrumenting participants' vehicles. The analyses used logistic regression to determine the likelihood of crash or near-crash involvement, Poisson log-linear regression to assess crash or near-crash rate, and ordinal logistic regression to assess driver maneuver appropriateness and crash or near-crash severity. These analyses did not account for any medical treatments for the sleep disorders. Females with restless legs syndrome/Willis-Ekbom disease (RLS/WED), drivers with insomnia or narcolepsy, are associated with significantly higher risk of crash or near-crash. Drivers with shift work sleep disorder (SWSD) are associated with significantly increased crash or near-crash rate. Females with RLS/WED or sleep apnea and drivers with SWSD are associated with less safe driver maneuver and drivers with periodic limb movement disorder are associated with more severe events. The four analyses provide no evidence of safety decrements associated with migraine. This study is the first examination on the association between seven sleep disorders and different measures of driving risk using large-scale naturalistic driving study data. The results corroborate much of the existing simulator and epidemiological research related to sleep-disorder patients and their driving safety, but add ecological validity to those findings. These results contribute to the empirical basis for medical professionals, policy makers, and employers in making decisions to aid individuals with sleep disorders in balancing safety and personal mobility.

  18. Country variations in depressive symptoms profile in Asian countries: Findings of the Research on Asia Psychotropic Prescription (REAP) studies.

    Science.gov (United States)

    Chee, Kok-Yoon; Tripathi, Adarsh; Avasthi, Ajit; Chong, Mian-Yoon; Xiang, Yu-Tao; Sim, Kang; Si, Tian-Mei; Kanba, Shigenobu; He, Yan-Ling; Lee, Min-Soo; Fung-Kum Chiu, Helen; Yang, Shu-Yu; Kuga, Hironori; Udormatn, Pichet; Kallivayalil, Roy A; Tanra, Andi J; Maramis, Margarita; Grover, Sandeep; Chin, Loi-Fei; Dahlan, Rahima; Mohamad Isa, Mohd Fadzli; Ebenezer, Esther Gunaseli M; Nordin, Norhayati; Shen, Winston W; Shinfuku, Naotaka; Tan, Chay-Hoon; Sartorius, Norman

    2015-09-01

    This study was to assess differences in the symptom profile of depressive illness across various countries/territories in Asia. The study was a part of the Research on Asia Psychotropic Prescription project. The participating countries/territories include China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, Singapore, Taiwan, and Thailand. The pattern of depressive symptoms in 1,400 subjects with depressive disorder from 42 psychiatric centers in 10 Asian countries/territories was assessed. We collected information on socio-demographic and clinical characteristics with a standardized protocol and data collection procedure. The most common presentations of depressive symptoms were persistent sadness, loss of interest, and insomnia. Similar findings were found regardless of the region, country, or its income level. Patients with depressive disorder from high-income countries presented significantly more with vegetative symptom cluster (P countries had significantly more with both mood (P countries, patients with depressive symptoms had significantly less mood symptom cluster (P countries/territories, core depressive symptoms remain the same. Variations have been found in presentation of depressive symptoms with regards to the level of income of countries. Physical or vegetative symptoms were reported more by centers in higher income countries, while depressive cognition and suicidal thoughts/acts were more frequently reported from lower income countries. © 2015 Wiley Publishing Asia Pty Ltd.

  19. Experimental findings on actinide recovery utilizing oxidation by peroxydisulfate followed by ion exchange: Fuel cycle research & development

    Energy Technology Data Exchange (ETDEWEB)

    Hobbs, D. T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Shehee, T. C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-08-31

    Our research seeks to determine if inorganic ion-exchange materials can be exploited to provide effective minor actinide (Am, Cm) separation from lanthanides. Previous work has established that a number of inorganic and UMOF ion-exchange materials exhibit varying affinities for actinides and lanthanides, which may be exploited for effective separations. During FY15, experimental work focused on investigating methods to oxidize americium in dilute nitric and perchloric acid with subsequent ion-exchange performance measurements of ion exchangers with the oxidized americium in dilute nitric acid. Ion-exchange materials tested included a variety of alkali titanates. Americium oxidation testing sought to determine the influence that other redox active components may have on the oxidation of AmIII. Experimental findings indicated that CeIII, NpV, and RuII are oxidized by peroxydisulfate, but there are no indications that the presence of CeIII, NpV, and RuII affected the rate or extent of americium oxidation at the concentrations of peroxydisulfate being used.

  20. Using Abductive Research Logic: "The Logic of Discovery", to Construct a Rigorous Explanation of Amorphous Evaluation Findings

    Science.gov (United States)

    Levin-Rozalis, Miri

    2010-01-01

    Background: Two kinds of research logic prevail in scientific research: deductive research logic and inductive research logic. However, both fail in the field of evaluation, especially evaluation conducted in unfamiliar environments. Purpose: In this article I wish to suggest the application of a research logic--"abduction"--"the logic of…

  1. Correspondence : Some general points regarding Ledberg and Wennberg, BMC Medical Research Methodology 2014 April 27;14:58

    NARCIS (Netherlands)

    Boehning, Dankmar; van der Heijden, Peter G. M.

    2015-01-01

    The purpose of this note is to contribute some general points on a recent paper by Ledberg and Wennberg (BMC Med Res Meth 14:58, 2014) which need to be rectified. They advocate the capture-removal estimator. First, we will discuss drawbacks of this estimator in comparison to the Lincoln-Petersen

  2. Experimental research and numerical optimisation of multi-point sheet metal forming implementation using a solid elastic cushion system

    Science.gov (United States)

    Tolipov, A. A.; Elghawail, A.; Shushing, S.; Pham, D.; Essa, K.

    2017-09-01

    There is a growing demand for flexible manufacturing techniques that meet the rapid changes in customer needs. A finite element analysis numerical optimisation technique was used to optimise the multi-point sheet forming process. Multi-point forming (MPF) is a flexible sheet metal forming technique where the same tool can be readily changed to produce different parts. The process suffers from some geometrical defects such as wrinkling and dimpling, which have been found to be the cause of the major surface quality problems. This study investigated the influence of parameters such as the elastic cushion hardness, blank holder force, coefficient of friction, cushion thickness and radius of curvature, on the quality of parts formed in a flexible multi-point stamping die. For those reasons, in this investigation, a multipoint forming stamping process using a blank holder was carried out in order to study the effects of the wrinkling, dimpling, thickness variation and forming force. The aim was to determine the optimum values of these parameters. Finite element modelling (FEM) was employed to simulate the multi-point forming of hemispherical shapes. Using the response surface method, the effects of process parameters on wrinkling, maximum deviation from the target shape and thickness variation were investigated. The results show that elastic cushion with proper thickness and polyurethane with the hardness of Shore A90. It has also been found that the application of lubrication cans improve the shape accuracy of the formed workpiece. These final results were compared with the numerical simulation results of the multi-point forming for hemispherical shapes using a blank-holder and it was found that using cushion hardness realistic to reduce wrinkling and maximum deviation.

  3. Ethical concerns and career satisfaction in obstetrics and gynecology: a review of recent findings from the Collaborative Ambulatory Research Network.

    Science.gov (United States)

    Farrow, Victoria A; Leddy, Meaghan A; Lawrence, Hal; Schulkin, Jay

    2011-09-01

    Obstetricians-gynecologists (ob-gyns) are frequently confronted with situations that have ethical implications (e.g., whether to accept gifts or samples from drug companies or disclosing medical errors to patients). Additionally, various factors, including specific job-related tasks, costs, and benefits, may impact ob-gyns' career satisfaction. Ethical concerns and career satisfaction can play a role in the quality of women's health care. This article summarizes the studies published between 2005 and 2009 by the Research Department of the American College of Obstetricians and Gynecologists, which encompass ethical concerns regarding interactions with pharmaceutical representatives and patient safety/medical error reporting, as well as ob-gyn career satisfaction. Additionally, a brief discussion regarding ethical concerns in the ob-gyn field, in general, highlights key topics for the last 30 years. Ethical dilemmas continue to be of concern for ob-gyns. Familiarity with guidelines on appropriate interactions with industry is associated with lower percentages of potentially problematic relationships with pharmaceutical industries. Physicians report that the expense of patient safety initiatives is one of the top barriers for improving patient safety, followed by fear of liability. Overall, respondents reported being satisfied with their careers. However, half of the respondents reported that they were extremely concerned about the impact of professional liability costs on the duration of their careers. Increased familiarity with guidelines may lead to a decreased ob-gyn reliance on pharmaceutical representatives and free samples, whereas specific and practical tools may help them implement patient safety techniques. The easing of malpractice insurance and threat of litigation may enhance career satisfaction among ob-gyns. This article will discuss related findings in recent years. Obstetricians & Gynecologists and Family Physicians. After the completing the CME

  4. Project-based production and project management: Findings and trends in research on temporary systems in multiple contexts

    Directory of Open Access Journals (Sweden)

    Tinus Pretorius

    2014-02-01

    Full Text Available Globalisation is challenging almost every aspect of the political, economic, social and technological environment. Organisations, whether public or private, have to adapt their strategies and operations to stay competitive and efficient. Historically, organisations adopted project-based operations as a mode to stay competitive, although the applications tended to be the oneoff type of operations such as construction and system development projects (Edum-Fotwe & McCaffer, 2000. As the world changed from an industrially driven to a more knowledge driven economy and the pace of continuous change became more intense, organisations adopted a project-based mode of operations on a broader scale. The knowledge economy lead to the creation of many service orientated industries. Organisations started facing portfolios of projects where the nature of these projects differed in technological complexity, urgency, customer value and social impact (Gutjahr & Froeschl, 2013. Based on their experience with more technically orientated projects, organisations focused their attention more intensely on new project management methods, tools and processes and not necessarily on the human and organisational interfaces. This paradigm changed however, especially since the 1980s and more and more organisations adopted temporary organisational forms (Bakker, 2010 in order to improve their competitiveness. The contributions in this special edition of the South African Journal of Economic and Management Sciences have a common focus on the importance of the human and organisational interface of project-based operations on project success. The purpose of this concluding article is to analyse the findings and recommendations in these papers and to detect trends and future research opportunities in the field of project-based operations.

  5. Game Design and Homemade PowerPoint Games: An Examination of the Justifications and a Review of the Research

    Science.gov (United States)

    Siko, Jason; Barbour, Michael

    2013-01-01

    Research on educational games often focuses on the benefits that playing games has on student achievement. However, there is a growing body of research examining the benefits of having students design games rather than play them. Problems with game design as an instructional tool include the additional instruction on the programming language…

  6. Focal points and developments in wind energy research of the Federal Ministry for the Environment since 2001

    Energy Technology Data Exchange (ETDEWEB)

    Kutscher, J. [Forschungszentrum Juelich GmbH (DE). Projekttraeger Juelich (PTJ)

    2007-07-01

    This article gives a short review on the wind energy research supported by the German Federal Government since 2001. The basis for this governmental support is the 5th Energy Research Programme of the Federal Government and under this programme the publication of funding schemes for wind energy research of November 2004 and of September 2006. The overall objectives of funding are directed towards a still improved and competitive position of wind energy in the national energy market as a renewable source with high potential. Further improvement of generator technologies, grid characteristics and production processes shall enable the wind industry to successfully participate in the rapidly growing world market and expand the wind energy deployment as a climate compatible technology worldwide. A focus in research is given to new offshore specific aspects especially for offshore wind energy deployment far from the shore, as it will be the case in Germany. The article gives some information about the development of the research budget and highlights some important research projects without being able to consider the complete spectrum of research of the last years. (orig.)

  7. Synthesis of qualitative linguistic research--a pilot review integrating and generalizing findings on doctor-patient interaction.

    Science.gov (United States)

    Nowak, Peter

    2011-03-01

    There is a broad range qualitative linguistic research (sequential analysis) on doctor-patient interaction that had only a marginal impact on clinical research and practice. At least in parts this is due to the lack of qualitative research synthesis in the field. Available research summaries are not systematic in their methodology. This paper proposes a synthesis methodology for qualitative, sequential analytic research on doctor-patient interaction. The presented methodology is not new but specifies standard methodology of qualitative research synthesis for sequential analytic research. This pilot review synthesizes twelve studies on German-speaking doctor-patient interactions, identifies 45 verbal actions of doctors and structures them in a systematics of eight interaction components. Three interaction components ("Listening", "Asking for information", and "Giving information") seem to be central and cover two thirds of the identified action types. This pilot review demonstrates that sequential analytic research can be synthesized in a consistent and meaningful way, thus providing a more comprehensive and unbiased integration of research. Future synthesis of qualitative research in the area of health communication research is very much needed. Qualitative research synthesis can support the development of quantitative research and of educational materials in medical training and patient training. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  8. Correspondence: Some general points regarding Ledberg and Wennberg, BMC Medical Research Methodology 2014 April 27;14:58.

    Science.gov (United States)

    Böhning, Dankmar; van der Heijden, Peter G M

    2015-07-07

    The purpose of this note is to contribute some general points on a recent paper by Ledberg and Wennberg (BMC Med Res Meth 14:58, 2014) which need to be rectified. They advocate the capture-removal estimator. First, we will discuss drawbacks of this estimator in comparison to the Lincoln-Petersen estimator. Second, we show that their evaluation of the Chao estimator is flawed. We conclude that some statements in Ledberg and Wennberg with respect to Chao's estimator and removal estimation need to be taken with great caution.

  9. The Impact of Personality Factors and Preceding User Comments on the Processing of Research Findings on Deep Brain Stimulation: A Randomized Controlled Experiment in a Simulated Online Forum

    OpenAIRE

    Feinkohl, Insa; Flemming, Danny; Cress, Ulrike; Kimmerle, Joachim

    2016-01-01

    Background Laypeople frequently discuss medical research findings on Web-based platforms, but little is known about whether they grasp the tentativeness that is inherent in these findings. Potential influential factors involved in understanding medical tentativeness have hardly been assessed to date. Objective The research presented here aimed to examine the effects of personality factors and of other users? previous contributions in a Web-based forum on laypeople?s understanding of the tenta...

  10. Who Has Used Internal Company Documents for Biomedical and Public Health Research and Where Did They Find Them?

    OpenAIRE

    Wieland, L. Susan; Rutkow, Lainie; Vedula, S. Swaroop; Kaufmann, Christopher N.; Rosman, Lori M.; Twose, Claire; Mahendraratnam, Nirosha; Dickersin, Kay

    2014-01-01

    OBJECTIVE: To describe the sources of internal company documents used in public health and healthcare research. METHODS: We searched PubMed and Embase for articles using internal company documents to address a research question about a health-related topic. Our primary interest was where authors obtained internal company documents for their research. We also extracted information on type of company, type of research question, type of internal documents, and funding source. RESULTS: Our search...

  11. Experiences in the Dissemination and Utilisation of Information and Communication Technology (ICT) Research Findings from Three Southern African Universities

    Science.gov (United States)

    Kaino, Luckson M.; Mtetwa, David; Kasanda, Choshi

    2014-01-01

    The dissemination and utilisation of research knowledge produced at universities has been debated in recent times. Recent changes and developments at universities suggest an entrepreneurial model of academic research production in which universities have the responsibility not only to carry out research and teaching but also to disseminate…

  12. The Continuing Search to Find a More Effective and Less Intimidating Way to Teach Research Methods in Higher Education

    Science.gov (United States)

    Bell, Robin

    2016-01-01

    Existing literature examining the teaching of research methods highlights difficulties students face when developing research competencies. Studies of student-centred teaching approaches have found increased student performance and improved confidence in undertaking research projects. To develop a student-centred approach, it could be beneficial…

  13. Research

    African Journals Online (AJOL)

    research process, as part of which students must find and appraise evidence from research.[5] This highlights that teaching research methodology is inclined towards equipping students ... Students believed that evidence-based practice was vital, yet their understanding of the concept was restricted when compared with the.

  14. Do countries rely on the World Health Organization for translating research findings into clinical guidelines? A case study.

    Science.gov (United States)

    Noor, Ramadhani A; Geldsetzer, Pascal; Bärnighausen, Till; Fawzi, Wafaie

    2016-10-06

    The World Health Organization's (WHO) antiretroviral therapy (ART) guidelines have generally been adopted rapidly and with high fidelity by countries in sub-Saharan Africa. Thus far, however, WHO has not published specific guidance on nutritional care and support for (non-pregnant) adults living with HIV despite a solid evidence base for some interventions. This offers an opportunity for a case study on whether national clinical guidelines in sub-Saharan Africa provide concrete recommendations in the face of limited guidance by WHO. This study, therefore, aims to determine if national HIV treatment guidelines in sub-Saharan Africa contain specific guidance on nutritional care and support for non-pregnant adults living with HIV. We identified the most recent national HIV treatment guidelines in sub-Saharan African countries with English as an official language. Using pre-specified criteria, we determined for each guideline whether it provides guidance to clinicians on each of five components of nutritional care and support for adults living with HIV: assessment of nutritional status, dietary counseling, micronutrient supplementation, ready-to-use therapeutic or supplementary foods, and food subsidies. We found that national HIV treatment guidelines in sub-Saharan Africa generally do not contain concrete recommendations on nutritional care and support for non-pregnant adults living with HIV. Given that decisions on nutritional care and support are inevitably being made at the clinician-patient level, and that clinicians have a relative disadvantage in systematically identifying, summarizing, and weighing up research evidence compared to WHO and national governments, there is a need for more specific clinical guidance. In our view, such guidance should at a minimum recommend daily micronutrient supplements for adults living with HIV who are in pre-ART stages, regular dietary counseling, periodic assessment of anthropometric status, and additional nutritional

  15. E-Cigarettes Use Behavior and Experience of Adults: Qualitative Research Findings to Inform E-Cigarette Use Measure Development.

    Science.gov (United States)

    Kim, Hyoshin; Davis, Andrew H; Dohack, Jaime L; Clark, Pamela I

    2017-02-01

    findings reveal that vaping is not a mere replacement for combustible cigarette smoking and that many users of e-cigarettes enjoy product characteristics such as flavors and "clouds" that are unavailable in combustible cigarettes. Therefore, commonly available cigarette smoking measures are not well suited to measurement of e-cigarette use behavior, and indication that new measures need to be developed to accurately track e-cigarette use. © The Author 2016. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  16. Researching the value system of interest groups as the starting point for directing urbanisation of the countryside

    Directory of Open Access Journals (Sweden)

    Mojca Golobič

    2001-01-01

    Full Text Available When planning rehabilitation of transitory, rural space, where processes of restructuring agriculture intertwine with urban processes, key definitions concern places where restructuring agriculture and changes in land use are causing degradation and places where further urbanisation or re-naturation are the better option. In these definitions it is necessary to follow opinions and goals of users that are nevertheless difficult to obtain in a mode that can be directly integrated in standardised rational procedures of physical planning. The presented procedure facilitates the procurement of such knowledge and its transparent integration in local development plans. Thus we can identify interest groups, their viewpoints, and potential conflicts in initial value systems and check their conflicting or harmonising starting points in space.

  17. Musical Development and Learning Characteristics of Students: A Compilation of Key Points from the Research Literature Organized by Age

    Science.gov (United States)

    Gooding, Lori; Standley, Jayne M.

    2011-01-01

    Development involves progressive changes in knowledge and abilities that occur across the life span. Current research on musical abilities suggests that the development of skills necessary for musicality begins in utero and continues through adulthood. Many of these skills, such as the ability to carry a tune, move in time to music, and respond…

  18. Decompression Sickness and U-2 Operations: Summary of Research, Findings, and Recommendations Regarding Use of Exercise During Prebreathe

    Science.gov (United States)

    2010-03-01

    Research Laboratory Hypobaric DCS Research Database developed at Brooks AFB, TX, which has detailed information on over 3,000 research chamber... hyperbaric oxygen therapy resulting in complete resolution of all symptoms. After instituting EDP, the same pilot flew 36 U-2 high flights without any...consultation with base SGP and USAFSAM Hyperbarics and MAJCOM/SGPA. Earlier guidance in the 1980’s was much more restrictive and, in fact, permanently

  19. The influence of organic production on food quality - research findings, gaps and future challenges

    DEFF Research Database (Denmark)

    Załęcka, Aneta; Bügel, Susanne Gjedsted; Paoletti, Flavio

    2014-01-01

    in order to identify research gaps and suggest future research challenges. Organic food is described according to a quality model already published. The influence of organic production on food quality is structured in primary production and processing. Furthermore, organic food authentication is discussed...... with so called 'conventional' food seems not to be appropriate, because 'conventional' is not defined. In organic food quality research a system approach is needed from which systemic markers can be selected. Research on the impact of processing technologies on the quality according to organic principles...

  20. An Overview of Research Strategies and Findings (1971-1975) of the Kamehameha Early Education Program. Technical Report #66.

    Science.gov (United States)

    Gallimore, Ronald; Tharp, Roland G.

    This report reviews the major lines of investigation of the Kamehameha Early Education Program (KEEP) for the period 1971-75. A brief introductory section describes the selection of initial research strategies, identification of problems, issues in research design (such as internal versus external validity) and problems pertaining to the process…

  1. Knowledge creation for practice in public sector management accounting by consultants and academics: Preliminary findings and directions for future research

    NARCIS (Netherlands)

    van Helden, G.J.; Aardema, H.; ter Bogt, H.J.; Groot, T.L.C.M.

    2010-01-01

    This study is about knowledge creation for practice in public sector management accounting by consultants and academics. It shows that researchers emphasize the importance of practice, but worry about the prospects of a successful cross-fertilization between practice and research, because of the

  2. Knowledge creation for practice in public sector management accounting by consultants and academics : Preliminary findings and directions for future research

    NARCIS (Netherlands)

    van Helden, G. Jan; Aardema, Harrie; ter Bogt, Henk J.; Groot, Tom L. C. M.

    This study is about knowledge creation for practice in public sector management accounting by consultants and academics. It shows that researchers emphasize the importance of practice, but worry about the prospects of a successful cross-fertilization between practice and research, because of the

  3. Young people's views about the purpose and composition of research ethics committees: findings from the PEARL qualitative study.

    Science.gov (United States)

    Audrey, Suzanne; Brown, Lindsey; Campbell, Rona; Boyd, Andy; Macleod, John

    2016-09-02

    Avon Longitudinal Study of Parents and Children (ALSPAC) is a birth cohort study within which the Project to Enhance ALSPAC through Record Linkage (PEARL) was established to enrich the ALSPAC resource through linkage between ALSPAC participants and routine sources of health and social data. PEARL incorporated qualitative research to seek the views of young people about data linkage, including their opinions about appropriate safeguards and research governance. In this paper we focus on views expressed about the purpose and composition of research ethics committees. Digitally recorded interviews were conducted with 48 participants aged 17-19 years. Participants were asked about whether medical research should be monitored and controlled, their knowledge of research ethics committees, who should sit on these committees and what their role should be. Interview recordings were fully transcribed and anonymised. Thematic analysis was undertaken, assisted by the Framework approach to data management. The majority of interviewees had little or no specific knowledge of ethics committees. Once given basic information about research ethics committees, only three respondents suggested there was no need for such bodies to scrutinise research. The key tasks of ethics committees were identified as monitoring the research process and protecting research participants. The difficulty of balancing the potential to inhibit research against the need to protect research participants was acknowledged. The importance of relevant research and professional expertise was identified but it was also considered important to represent wider public opinion, and to counter the bias potentially associated with self-selection possibly through a selection process similar to 'jury duty'. There is a need for more education and public awareness about the role and composition of research ethics committees. Despite an initial lack of knowledge, interviewees were able to contribute their ideas and balance

  4. Finding the Words to Work Together: Developing a Research Design to Explore Risk and Adult Protection in Co-Produced Research

    Science.gov (United States)

    Brookes, Ian; Archibald, Sylvia; McInnes, Kerry; Cross, Beth; Daniel, Brigid; Johnson, Fiona

    2012-01-01

    Although co-production of research with people who access support services is increasingly common, details about how people who access support services can take more of an assertive role in developing research proposals and method design remains sketchy. This article reflects on the development of a research project on adult protection practice in…

  5. Procedures of recruiting, obtaining informed consent, and compensating research participants in Qatar: findings from a qualitative investigation.

    Science.gov (United States)

    Killawi, Amal; Khidir, Amal; Elnashar, Maha; Abdelrahim, Huda; Hammoud, Maya; Elliott, Heather; Thurston, Michelle; Asad, Humna; Al-Khal, Abdul Latif; Fetters, Michael D

    2014-02-04

    Very few researchers have reported on procedures of recruiting, obtaining informed consent, and compensating participants in health research in the Arabian Gulf Region. Empirical research can inform the debate about whether to adjust these procedures for culturally diverse settings. Our objective was to delineate procedures related to recruiting, obtaining informed consent, and compensating health research participants in the extremely high-density multicultural setting of Qatar. During a multistage mixed methods project, field observations and qualitative interviews were conducted in a general medicine clinic of a major medical center in Qatar. Participants were chosen based on gender, age, literacy, and preferred language, i.e., Arabic, English, Hindi and Urdu. Qualitative analysis identified themes about recruitment, informed consent, compensation, and other research procedures. A total of 153 individuals were approached and 84 enrolled; the latter showed a diverse age range (18 to 75 years); varied language representation: Arabic (n = 24), English (n = 20), Hindi (n = 20), and Urdu (n = 20); and balanced gender distribution: women (n = 43) and men (n = 41). Primary reasons for 30 declinations included concern about interview length and recording. The study achieved a 74% participation rate. Qualitative analytics revealed key themes about hesitation to participate, decisions about participation with family members as well as discussions with them as "incidental research participants", the informed consent process, privacy and gender rules of the interview environment, reactions to member checking and compensation, and motivation for participating. Vulnerability emerged as a recurring issue throughout the process among a minority of participants. This study from Qatar is the first to provide empirical data on recruitment, informed consent, compensation and other research procedures in a general adult population in the Middle East and Arabian Gulf. This

  6. Auto-ethnographical investigation of turning points in dance education – a method for creating awareness of one’s own pre-understanding in qualitative research

    Directory of Open Access Journals (Sweden)

    Trine Ørbæk

    2013-06-01

    Full Text Available This article presents an auto-ethnographical investigation of a pedagogical practice in creative dance education. This research is a part of the PhD-project “To create dance” in physical education teacher education based at The Norwegian School of Sport Sciences and The Norwegian National Graduate School in Teacher Education. The method used is based on life stories, and turning points are used as analytical tools. The turning point analysis highlights that an auto-ethnographical investigation is relevant when it comes to creating awareness of pre-understandings in the development of pedagogical experiences from one’s own research field. In addition, the article shows that the turning point analysis may contribute to increasing knowledge on how one’s own experience can change when narrated in new ways. Finally, the study shows that making use of auto-ethnography may also have value as a reflexive approach for becoming more conscious of one’s own research process.

  7. Who has used internal company documents for biomedical and public health research and where did they find them?

    Directory of Open Access Journals (Sweden)

    L Susan Wieland

    Full Text Available OBJECTIVE: To describe the sources of internal company documents used in public health and healthcare research. METHODS: We searched PubMed and Embase for articles using internal company documents to address a research question about a health-related topic. Our primary interest was where authors obtained internal company documents for their research. We also extracted information on type of company, type of research question, type of internal documents, and funding source. RESULTS: Our searches identified 9,305 citations of which 357 were eligible. Scanning of reference lists and consultation with colleagues identified 4 additional articles, resulting in 361 included articles. Most articles examined internal tobacco company documents (325/361; 90%. Articles using documents from pharmaceutical companies (20/361; 6% were the next most common. Tobacco articles used documents from repositories; pharmaceutical documents were from a range of sources. Most included articles relied upon internal company documents obtained through litigation (350/361; 97%. The research questions posed were primarily about company strategies to promote or position the company and its products (326/361; 90%. Most articles (346/361; 96% used information from miscellaneous documents such as memos or letters, or from unspecified types of documents. When explicit information about study funding was provided (290/361 articles, the most common source was the US-based National Cancer Institute. We developed an alternative and more sensitive search targeted at identifying additional research articles using internal pharmaceutical company documents, but the search retrieved an impractical number of citations for review. CONCLUSIONS: Internal company documents provide an excellent source of information on health topics (e.g., corporate behavior, study data exemplified by articles based on tobacco industry documents. Pharmaceutical and other industry documents appear to have been

  8. Who has used internal company documents for biomedical and public health research and where did they find them?

    Science.gov (United States)

    Wieland, L Susan; Rutkow, Lainie; Vedula, S Swaroop; Kaufmann, Christopher N; Rosman, Lori M; Twose, Claire; Mahendraratnam, Nirosha; Dickersin, Kay

    2014-01-01

    To describe the sources of internal company documents used in public health and healthcare research. We searched PubMed and Embase for articles using internal company documents to address a research question about a health-related topic. Our primary interest was where authors obtained internal company documents for their research. We also extracted information on type of company, type of research question, type of internal documents, and funding source. Our searches identified 9,305 citations of which 357 were eligible. Scanning of reference lists and consultation with colleagues identified 4 additional articles, resulting in 361 included articles. Most articles examined internal tobacco company documents (325/361; 90%). Articles using documents from pharmaceutical companies (20/361; 6%) were the next most common. Tobacco articles used documents from repositories; pharmaceutical documents were from a range of sources. Most included articles relied upon internal company documents obtained through litigation (350/361; 97%). The research questions posed were primarily about company strategies to promote or position the company and its products (326/361; 90%). Most articles (346/361; 96%) used information from miscellaneous documents such as memos or letters, or from unspecified types of documents. When explicit information about study funding was provided (290/361 articles), the most common source was the US-based National Cancer Institute. We developed an alternative and more sensitive search targeted at identifying additional research articles using internal pharmaceutical company documents, but the search retrieved an impractical number of citations for review. Internal company documents provide an excellent source of information on health topics (e.g., corporate behavior, study data) exemplified by articles based on tobacco industry documents. Pharmaceutical and other industry documents appear to have been less used for research, indicating a need for funding for

  9. Research to Operations: From Point Positions, Earthquake and Tsunami Modeling to GNSS-augmented Tsunami Early Warning

    Science.gov (United States)

    Stough, T.; Green, D. S.

    2017-12-01

    This collaborative research to operations demonstration brings together the data and algorithms from NASA research, technology, and applications-funded projects to deliver relevant data streams, algorithms, predictive models, and visualization tools to the NOAA National Tsunami Warning Center (NTWC) and Pacific Tsunami Warning Center (PTWC). Using real-time GNSS data and models in an operational environment, we will test and evaluate an augmented capability for tsunami early warning. Each of three research groups collect data from a selected network of real-time GNSS stations, exchange data consisting of independently processed 1 Hz station displacements, and merge the output into a single, more accurate and reliable set. The resulting merged data stream is delivered from three redundant locations to the TWCs with a latency of 5-10 seconds. Data from a number of seismogeodetic stations with collocated GPS and accelerometer instruments are processed for displacements and seismic velocities and also delivered. Algorithms for locating and determining the magnitude of earthquakes as well as algorithms that compute the source function of a potential tsunami using this new data stream are included in the demonstration. The delivered data, algorithms, models and tools are hosted on NOAA-operated machines at both warning centers, and, once tested, the results will be evaluated for utility in improving the speed and accuracy of tsunami warnings. This collaboration has the potential to dramatically improve the speed and accuracy of the TWCs local tsunami information over the current seismometer-only based methods. In our first year of this work, we have established and deployed an architecture for data movement and algorithm installation at the TWC's. We are addressing data quality issues and porting algorithms into the TWCs operating environment. Our initial module deliveries will focus on estimating moment magnitude (Mw) from Peak Ground Displacement (PGD), within 2

  10. Work in progress Tim Radford on research that aims to find a tiny error in Einstein's theory of special relativity

    CERN Multimedia

    Radford, T

    2004-01-01

    "Ben Varcoe wants to find a relatively small mistake in Einstein's theory of special relativity. To do this, he will slow light down from 300,000 km per second to 10 metres per second - about the speed of Darren Campbell - and see how it behaves" (1 page)

  11. Accelerated Proficiency and Facilitated Retention: Recommendations Based on an Integration of Research and Findings from a Working Meeting

    Science.gov (United States)

    2010-12-01

    skill loss occurs early, within the first year, and that skill loss slows marginally after that. To relativize the above findings, which might be...civilian and contractor scientists, engineers and technicians. He directs all civil engineering, security, morale and welfare, and professional

  12. Finding the team for Mars: a psychological and human factors analysis of a Mars Desert Research Station crew.

    Science.gov (United States)

    Sawyer, Benjamin D; Hancock, P A; Deaton, John; Suedfeld, Peter

    2012-01-01

    A two-week mission in March and April of 2011 sent six team members to the Mars Desert Research Station (MDRS). MDRS, a research facility in the high Utah desert, provides an analogue for the harsh and unusual working conditions that will be faced by men and women who one day explore Mars. During the mission a selection of quantitative and qualitative psychological tests were administered to the international, multidisciplinary team. A selection of the results are presented along with discussion.

  13. Behind the Headlines: Media Representation of Children and Young People in Northern Ireland:Summary of Research Findings

    OpenAIRE

    Gordon, Faith; McAlister, Siobhán; Scraton, Phil

    2015-01-01

    Funded by the Economic and Social Research Council this partnership project between the Childhood, Transition and Social Justice Initiative at Queen’s University and Include Youth focuses on the negative stereotyping of children and young people and the role and responsibilities of the media in the creation and transmission of negative images. Engaging with children, young people, organisations working with children and young people and media representatives, the project uses research evidenc...

  14. Consulting patients in setting priorities in Myalgic Encephalomyelitis (M.E.) research: findings from a national on-line survey.

    Science.gov (United States)

    Childs, Nicola; Robinson, Lisa; Chowdhury, Sonya; Ogden, Clare; Newton, Julia L

    2015-01-01

    Myalgic encephalitis (M.E.) is a common condition, the cause of which is not known and there are no treatments available. In this study the national patient support group Action for M.E. sought the opinions of their members via an online survey as to what they felt should be future priorities for M.E. Respondents were asked what they considered first, second and third research priorities to be from a list of 13 pre-defined options. Individuals were invited to provide additional free text comments about Action for M.E.'s research priorities in general. Of the 1144 respondents: 822 had M.E.; 94 were a supporting a member of Action for M.E. ; 66 were carers for someone with M.E.; 26 were professionals with an interest in M.E.; 136 had a family member or colleague with M.E. Individuals selected more than one category as applicable. The top five research priorities identified were: disease processes to achieve a better understanding of the causes of M.E.; more effective treatments; faster and more accurate diagnosis; clinical course of M.E.; outcomes and natural history; and severely affected patients. Least popular priorities were: sleep; economic research towards identifying the cost of ME; and psychological aspects. Much of the free text comments emphasised the importance of funding biomedical research into disease processes to achieve a better understanding of the causes of M.E. Three themes were identified in relation to this topic: accurate diagnosis and awareness; risk factors and causes; drug development and curative therapies. In conclusion; individuals affected by M.E. have clear views regarding priorities for research investment. These have informed Action for M.E.'s ongoing research strategy and ultimately will inform national and international research priorities.

  15. Finding the community in sustainable online community engagement: Not-for-profit organisation websites, service-learning and research

    OpenAIRE

    Dodd, Alice

    2017-01-01

    This article explores the use of action research (2008–2014) based on a case study of the Sustainable Online Community Engagement (SOCE) Project, a service-learning project in which University of South Australia students build websites for not-for-profit (NFP) organisations, to demonstrate that effective teaching, public service and research are interdependent. A significant problem experienced in the SOCE project was that, despite some training and ongoing assistance, the community organisat...

  16. Finding the community in sustainable online community engagement: Not-for-profit organisation websites, service-learning and research

    Directory of Open Access Journals (Sweden)

    Alice Dodd

    2017-06-01

    Full Text Available This article explores the use of action research (2008–2014 based on a case study of the Sustainable Online Community Engagement (SOCE Project, a service-learning project in which University of South Australia students build websites for not-for-profit (NFP organisations, to demonstrate that effective teaching, public service and research are interdependent. A significant problem experienced in the SOCE project was that, despite some training and ongoing assistance, the community organisations reported that they found it difficult to make effective use of their websites. One of the proposed solutions was to develop an online community of the participating organisations that would be self-supporting, member-driven and collaborative, and enable the organisations to share information about web-based technology. The research reported here explored the usefulness of developing such an online community for the organisations involved and sought alternative ways to assist the organisations to maintain an effective and sustainable web presence. The research used a three-phase ethnographic action research approach. The first phase was a content analysis and review of the editing records of 135 organisational websites hosted by the SOCE project. The second phase was an online survey sent to 145 community organisation members responsible for the management of these websites, resulting in 48 responses. The third phase consisted of semi-structured, in-depth interviews with 18 of the website managers from 12 of these organisations. The research revealed the extent to which organisations were unable to manage their websites and found that the proposed solution of an online community would not be useful. More importantly, it suggested other useful strategies which have been implemented. In Furco’s (2010 model of the engaged campus, public engagement can be used to advance the public service, teaching and research components of higher education’s tripartite

  17. Tipping Point

    Medline Plus

    Full Text Available ... en español Blog About OnSafety CPSC Stands for Safety The Tipping Point Home > 60 Seconds of Safety (Videos) > The Tipping Point The Tipping Point by ... danger death electrical fall furniture head injury product safety television tipover tv Watch the video in Adobe ...

  18. Developing skills and competence of employees of the Kujawsko-Pomorskie regional operational programme managing body – research findings

    Directory of Open Access Journals (Sweden)

    Małgorzata Michalcewicz-Kaniowska

    2011-01-01

    Full Text Available In the contemporary world it is the employees or the human capital of any company who are responsible for effective management and caring for the future of their business. Organisations change all the time which means that continual staff training should be provided. The purpose of the research was to evaluate the training policy of the managing body of the Kujawsko-Pomorskie Regional Operational Programme (IZ RPO WK-P and its employees’ development potential. The research participants preferred mentoring (47%, coaching (27% and briefing (26% techniques. They also benefited from a range of educational techniques such as training courses, post-graduate studies etc. and a wide choice of subjects. Thus, it is necessary to conduct periodic research on training requirements, focusing on subjects and training techniques.

  19. Changes in symptoms during urologic chronic pelvic pain syndrome symptom flares: findings from one site of the MAPP Research Network.

    Science.gov (United States)

    Sutcliffe, Siobhan; Colditz, Graham A; Pakpahan, Ratna; Bradley, Catherine S; Goodman, Melody S; Andriole, Gerald L; Lai, H Henry

    2015-02-01

    To provide the first description and quantification of symptom changes during interstitial cystitis/bladder pain syndrome and chronic prostatitis/chronic pelvic pain syndrome symptom exacerbations ("flares"). Participants at one site of the Trans-Multidisciplinary Approaches to the study of chronic Pelvic Pain Epidemiology and Phenotyping Study completed two 10-day diaries over the 1-year study follow-up period, one at baseline and one during their first flare (if not at baseline). On each day of the diary, participants reported whether they were currently experiencing a flare, defined as "symptoms that are much worse than usual" for at least 1 day, and their levels of urination-related pain, pelvic pain, urgency, and frequency on a scale of 0-10. Linear mixed models were used to calculate mean changes in symptoms between non-flare and flare days from the same participant. Eighteen of 27 women and 9 of 29 men reported at least one flare during follow-up, for a total of 281 non-flare and 210 flare days. Of these participants, 44.4% reported one flare, 29.6% reported two flares, and 25.9% reported ≥ 3 flares over the combined 20-day diary observation period, with reported flares ranging in duration from 1 day to >2 weeks. During these flares, each of the main symptoms worsened significantly by a mean of at least two points and total symptoms worsened by a mean of 11 points for both sexes (all P ≤ 0.01). Flares are common and correspond to a global worsening of urologic and pelvic pain symptoms. © 2013 Wiley Periodicals, Inc.

  20. Findings on the Development and Use of Technology-Infused Curricula in Preschool Classrooms. Interactive STEM Research Brief

    Science.gov (United States)

    Stiles, Jennifer; Louie, Jo

    2016-01-01

    Mobile tablets are becoming more prevalent in educational settings, but little is known about the impact of using technology-infused curricula in preschool classrooms. The research summarized in this brief suggests that well-designed tablet-based activities can indeed improve student learning outcomes at the preschool level. These positive…

  1. The influence of organic production on food quality - research findings, gaps and future challenges.

    Science.gov (United States)

    Załęcka, Aneta; Bügel, Susanne; Paoletti, Flavio; Kahl, Johannes; Bonanno, Adriana; Dostalova, Anne; Rahmann, Gerold

    2014-10-01

    Although several meta-analysis studies have been published comparing the quality of food derived from organic and non-organic origin, it is still not clear if food from organic production per se can guarantee product-related added value to consumers. This paper aims to summarize the status quo in order to identify research gaps and suggest future research challenges. Organic food is described according to a quality model already published. The influence of organic production on food quality is structured in primary production and processing. Furthermore, organic food authentication is discussed. Organic food seems to contain fewer pesticide residues and statistically more selected health-related compounds such as polyphenols in plant products and polyunsaturated fatty acids in milk and meat products, but the health relevance for consumers is not clear yet. Comparing food from organic origin with so called 'conventional' food seems not to be appropriate, because 'conventional' is not defined. In organic food quality research a system approach is needed from which systemic markers can be selected. Research on the impact of processing technologies on the quality according to organic principles seems of high relevance, since most of the food is processed. © 2014 Society of Chemical Industry.

  2. Dentists' use of caries risk assessment in children: findings from the Dental Practice-Based Research Network

    DEFF Research Database (Denmark)

    Riley, Joseph L; Qvist, Vebeke; Fellows, Jeffrey L

    2010-01-01

    This study surveyed Dental Practice-Based Research Network (DPBRN) member dentists (from four regions in the U.S. and Scandinavia) who perform restorative dentistry in their practices. The survey asked a range of questions about caries risk assessment in patients aged 6 to 18. Among respondents, 73...

  3. Restorative treatment thresholds for interproximal primary caries based on radiographic images: findings from the Dental Practice-Based Research Network

    DEFF Research Database (Denmark)

    Gordan, Valeria V; Garvan, Cynthia W; Heft, Marc W

    2009-01-01

    with restorative intervention in lesions that have penetrated only the enamel surface. This study surveyed dentists from the Dental Practice-Based Research Network (DPBRN) who had reported doing at least some restorative dentistry (n = 901). Dentists were asked to indicate the depth at which they would restore...

  4. The Search for Extension: 7 Steps to Help People Find Research-Based Information on the Internet

    Science.gov (United States)

    Hill, Paul; Rader, Heidi B.; Hino, Jeff

    2012-01-01

    For Extension's unbiased, research-based content to be found by people searching the Internet, it needs to be organized in a way conducive to the ranking criteria of a search engine. With proper web design and search engine optimization techniques, Extension's content can be found, recognized, and properly indexed by search engines and…

  5. Young Children's Research Behaviour? Children Aged Four to Eight Years Finding Solutions at Home and at School

    Science.gov (United States)

    Murray, Jane M.

    2013-01-01

    Children's research abilities have become increasingly recognised by adults, yet children remain excluded from the academy. This restricts children's freedom to make choices in matters affecting them, underestimates their capabilities and denies children particular rights. The present paper reports on young children's problem-solving as part of a…

  6. Methods and impact of engagement in research, from theory to practice and back again: early findings from the Patient-Centered Outcomes Research Institute.

    Science.gov (United States)

    Forsythe, Laura; Heckert, Andrea; Margolis, Mary Kay; Schrandt, Suzanne; Frank, Lori

    2018-01-01

    Since 2012, PCORI has been funding patient-centered comparative effectiveness research with a requirement for engaging patients and other stakeholders in the research, a requirement that is unique among the US funders of clinical research. This paper presents PCORI's evaluation framework for assessing the short- and long-term impacts of engagement; describes engagement in PCORI projects (types of stakeholders engaged, when in the research process they are engaged and how they are engaged, contributions of their engagement); and identifies the effects of engagement on study design, processes, and outcomes selection, as reported by both PCORI-funded investigators and patient and other stakeholder research partners. Detailed quantitative and qualitative information collected annually from investigators and their partners was analyzed via descriptive statistics and cross-sectional qualitative content and thematic analysis, and compared against the outcomes expected from the evaluation framework and its underlying conceptual model. The data support the role of engaged research partners in refinements to the research questions, selection of interventions to compare, choice of study outcomes and how they are measured, contributions to strategies for recruitment, and ensuring studies are patient-centered. The evaluation framework and the underlying conceptual model are supported by results to date. PCORI will continue to assess the effects of engagement as the funded projects progress toward completion, dissemination, and uptake into clinical decision making.

  7. Searching for sex- and gender-sensitive tuberculosis research in public health: finding a needle in a haystack

    Science.gov (United States)

    Vissandjee, Bilkis; Mourid, Assia; Greenaway, Christina A; Short, Wendy E; Proctor, Jodi A

    2016-01-01

    Despite broadening consideration of sex- and gender-based issues in health research, when seeking information on how sex and gender contribute to disease contexts for specific health or public health topics, a lack of consistent or systematic use of terminology in health literature means that it remains difficult to identify research with a sex or gender focus. These inconsistencies are driven, in part, by the complexity and terminological inflexibility of the indexing systems for gender- and sex-related terms in public health databases. Compounding the issue are authors’ diverse vocabularies, and in some cases lack of accuracy in defining and using fundamental sex–gender terms in writing, and when establishing keyword lists and search criteria. Considering the specific case of the tuberculosis (TB) prevention and management literature, an analysis of sex and gender sensitivity in three health databases was performed. While there is an expanding literature exploring the roles of both sex and gender in the trajectory and lived experience of TB, we demonstrate the potential to miss relevant research when attempting to retrieve literature using only the search criteria currently available. We, therefore, argue that for good clinical practice to be achieved; there is a need for both public health researchers and users to be better educated in appropriate usage of the terminology associated with sex and gender. In addition, public health database indexers ought to accept the task of developing and implementing adequate definitions of sex and gender terms so as to facilitate access to sex- and gender-related research. These twin advances will allow clinicians to more readily recognize and access knowledge pertaining to systems of redress that respond to gendered risks that compound existing health inequalities in disease management and control, particularly when dealing with already complex diseases. Given the methodological and linguistic challenges presented by the

  8. Searching for sex- and gender-sensitive tuberculosis research in public health: finding a needle in a haystack.

    Science.gov (United States)

    Vissandjee, Bilkis; Mourid, Assia; Greenaway, Christina A; Short, Wendy E; Proctor, Jodi A

    2016-01-01

    Despite broadening consideration of sex- and gender-based issues in health research, when seeking information on how sex and gender contribute to disease contexts for specific health or public health topics, a lack of consistent or systematic use of terminology in health literature means that it remains difficult to identify research with a sex or gender focus. These inconsistencies are driven, in part, by the complexity and terminological inflexibility of the indexing systems for gender- and sex-related terms in public health databases. Compounding the issue are authors' diverse vocabularies, and in some cases lack of accuracy in defining and using fundamental sex-gender terms in writing, and when establishing keyword lists and search criteria. Considering the specific case of the tuberculosis (TB) prevention and management literature, an analysis of sex and gender sensitivity in three health databases was performed. While there is an expanding literature exploring the roles of both sex and gender in the trajectory and lived experience of TB, we demonstrate the potential to miss relevant research when attempting to retrieve literature using only the search criteria currently available. We, therefore, argue that for good clinical practice to be achieved; there is a need for both public health researchers and users to be better educated in appropriate usage of the terminology associated with sex and gender. In addition, public health database indexers ought to accept the task of developing and implementing adequate definitions of sex and gender terms so as to facilitate access to sex- and gender-related research. These twin advances will allow clinicians to more readily recognize and access knowledge pertaining to systems of redress that respond to gendered risks that compound existing health inequalities in disease management and control, particularly when dealing with already complex diseases. Given the methodological and linguistic challenges presented by the

  9. Finding research information on the web: how to make the most of Google and other free search tools.

    Science.gov (United States)

    Blakeman, Karen

    2013-01-01

    The Internet and the World Wide Web has had a major impact on the accessibility of research information. The move towards open access and development of institutional repositories has resulted in increasing amounts of information being made available free of charge. Many of these resources are not included in conventional subscription databases and Google is not always the best way to ensure that one is picking up all relevant material on a topic. This article will look at how Google's search engine works, how to use Google more effectively for identifying research information, alternatives to Google and will review some of the specialist tools that have evolved to cope with the diverse forms of information that now exist in electronic form.

  10. The genetics of auricular development and malformation: new findings in model systems driving future directions for microtia research

    Science.gov (United States)

    Cox, Timothy C.; Camci, Esra D.; Vora, Siddharth; Luquetti, Daniela V.; Turner, Eric E.

    2014-01-01

    Microtia is a term used to describe a wide array of phenotypic presentations of the outer ear. Although the majority of the cases are isolated in nature, much of our understanding of the causes of microtia has been driven by the identification of genes underlying syndromic forms where the anomaly co-presents with various other craniofacial and extra-craniofacial structural defects. In this review we discuss recent findings in mice deficient in Hoxa2, a key regulator of branchial arch patterning, which has necessitated a revision to the canonical model of pinna morphogenesis. The revised model will likely impact current classification schemes for microtia and, as we argue in this review, the interpretation of the developmental basis for various auricular malformations. In addition, we highlight recent studies in other mammalian species that are providing the first clues as to possible causes of at least some isolated anomalies and thus should now accelerate the search for the more elusive genetic contributions to the many isolated and non-syndromic cases of microtia. These findings, together with the application of new genome-level sequencing technologies and more thorough quantitative assessment of available mutant mouse resources, promise an exciting future for genetic studies in microtia. PMID:24880027

  11. Caring communities as collective learning process: findings and lessons learned from a participatory research project in Austria.

    Science.gov (United States)

    Wegleitner, Klaus; Schuchter, Patrick

    2018-04-01

    By now, the public health end-of-life care approach is well established and has induced diverse initiatives-subsumed under the concept of compassionate or caring communities-to engage the community in supporting vulnerable, dying people and their beloved ones. In the light of a participatory research project our paper examines the question: what are the deeper ideas behind caring communities and what constitutes a caring community? A multi-level analysis based on (I) qualitative research with focus groups and interviews with community members within the project; (II) the reflection of the role of participatory research in caring community initiatives, and (III) the meta-analysis of an international expert workshop, which allowed to discuss our experiences and insights in the light of international caring community models and expertise. Our analysis of qualities ("ingredients") of a caring community, from the perspective of community members, highlighted the importance of the co-creation of supportive care relationships in the local care web, through everyday life solidarity in the neighbourhood, appreciating and exchanging the wisdom of care, and also marked the role of professionals as enablers. Participatory research in caring community developments has the potential to engage and empower citizens, and to interlink existential care-stories with questions about the structural and political environments of appropriate end-of-life care. The caring community movement and public health end-of-life care has to maintain their critical potential against the commercialization and fragmentation of care (services), but also without "romanticizing" communities. Prospective caring community progresses need (I) an ecological health-promotion framework for action and (II) social learning processes along the existential experiences and the wisdom of community members, complementing each other. Organizing existential-political care dialogues can contribute to an ethic of caring

  12. A single qualitative study can show same findings as years of quantitative research: Obstructive sleep apnoea as an example

    Directory of Open Access Journals (Sweden)

    Howard Tandeter

    2016-06-01

    Full Text Available Background Many years of quantitative research led to our present knowledge of the symptoms and associated features (S&AF of the obstructive sleep apnoea (OSA syndrome. Aims 1. To prove that a qualitative research approach may identify symptoms and associated features of OSA in less time/effort than that used in a quantitative approach; 2. To describe the experience of patients with OSA and the effects of the syndrome on their quality of life and that of their spouses and families (issues that quantitative methods fail to recognize. Methods We used a narrative inquiry methodology (qualitative research. The sample was selected using the “snowball sampling technique". The sample included 10 patients with moderate to severe OSA who had good adherence to CPAP and significant clinical improvement after treatment, and 3 of the patient’s spouses. Results The following issues were identified: A long pre-diagnosis phase of OSA (20 years in one of the patients; Characteristic S&AF of the syndrome as experienced by patients and their spouses; The need for increased awareness of both the public and the medical establishment in regards to this disorder; Premature ejaculation (not reported previously and nightmares (non-conclusive in the literature were identified and improved with CPAP therapy. Conclusion With the use of quantitative research methods it took decades to discover things that we found in one simple qualitative study. We therefore urge scientists to use more often these qualitative methods when looking for S&AF of diseases and syndromes.

  13. Money for Research, Not for Energy Bills: Finding Energy and Cost Savings in High Performance Computer Facility Designs

    Energy Technology Data Exchange (ETDEWEB)

    Drewmark Communications; Sartor, Dale; Wilson, Mark

    2010-07-01

    High-performance computing facilities in the United States consume an enormous amount of electricity, cutting into research budgets and challenging public- and private-sector efforts to reduce energy consumption and meet environmental goals. However, these facilities can greatly reduce their energy demand through energy-efficient design of the facility itself. Using a case study of a facility under design, this article discusses strategies and technologies that can be used to help achieve energy reductions.

  14. Social Media Technology and Public Health in Ontario: Findings from a Planning Meeting Exploring Current Practices and Future Research Directions.

    Science.gov (United States)

    Booth, Richard; McMurray, Josephine; Regan, Sandra; Kothari, Anita; Donelle, Lorie; McBride, Susan; Sobel, Annette; Hall, Jodi; Fraser, Robert; Foisey, Lyndsay

    2017-01-01

    In the province of Ontario, many of the public health units (PHUs) now possess and use social media as part of their daily health promotion and communication operations. To explore this topic, a planning meeting was held to generate deeper insights toward the use of these forms of technology for preventative services delivery. The planning meeting was held with 50 participants, comprising representatives from 20 of the 36 PHUs in Ontario, interested academics, students and government representatives. A nominal group technique (NGT) was used to build consensus related to future research needs, as related to public health and social media. Participants generated a range of insights around the use of social media, including the need for: leadership buy-in and resource allocation; social media policy and governance structure; performance measurement and evaluation; practices related to engagement with program recipients and addressing the lack of resources faced by many health units. Future research priorities were also generated, related to evaluating the cost-benefit of social media activities and understanding behaviour change implications. Further research is needed to evaluate the functionality, leadership and competency requirements and impact(s) of these new forms of health communication technology within public health service delivery. Copyright © 2017 Longwoods Publishing.

  15. Development of a Pilot Data Management Infrastructure for Biomedical Researchers at University of Manchester – Approach, Findings, Challenges and Outlook of the MaDAM Project

    Directory of Open Access Journals (Sweden)

    Meik Poschen

    2012-12-01

    Full Text Available Management and curation of digital data has been becoming ever more important in a higher education and research environment characterised by large and complex data, demand for more interdisciplinary and collaborative work, extended funder requirements and use of e-infrastructures to facilitate new research methods and paradigms. This paper presents the approach, technical infrastructure, findings, challenges and outlook (including future development within the successor project, MiSS of the ‘MaDAM: Pilot data management infrastructure for biomedical researchers at University of Manchester’ project funded under the infrastructure strand of the JISC Managing Research Data (JISCMRD programme. MaDAM developed a pilot research data management solution at the University of Manchester based on biomedical researchers’ requirements, which includes technical and governance components with the flexibility to meet future needs across multiple research groups and disciplines.

  16. Patient responses to research recruitment and follow-up surveys: findings from a diverse multicultural health care setting in Qatar

    Directory of Open Access Journals (Sweden)

    Amal Khidir

    2016-01-01

    Full Text Available Abstract Background Health care researchers working in the Arabian Gulf need information on how to optimize recruitment and retention of study participants in extremely culturally diverse settings. Implemented in Doha, Qatar in 2012 with 4 language groups, namely Arabic, English, Hindi, and Urdu, this research documents persons’ responses to recruitment, consent, follow-up, and reminder procedures during psychometric testing of the Multicultural Assessment Instrument (MAI, a novel self- or interviewer-administered survey. Methods Bilingual research assistants recruited adults in outpatient clinics by approaching persons in particular who appeared to be from a target language group. Participants completed the MAI, a second acculturation instrument used for content-validity assessment, and a demographics questionnaire. Participants were asked to take the MAI again in 2–3 weeks, in person or by post, to assess test-retest reliability. Recruitment data were analyzed by using nonparametric statistics. Results Of 1503 persons approached during recruitment, 400 enrolled (27 %—100 per language group. The enrollment rates in the language groups were: Arabic-32 %; English-33 %; Hindi-18 %; Urdu-30 %. The groups varied somewhat in their preferences regarding consent procedure, follow-up survey administration, contact mode for follow-up reminders, and disclosure of personal mailing address (for postal follow-up. Over all, telephone was the preferred medium for follow-up reminders. Of 64 persons who accepted a research assistant’s invitation for in-person follow-up, 40 participants completed the interview (follow-up rate, 63 %; among 126 persons in the postal group with a deliverable address, 29 participants mailed back a completed follow-up survey (response rate, 23 %. Conclusions Researchers in the Arabian Gulf face challenges to successfully identify, enroll, and retain eligible study participants. Although bilingual assistants

  17. [Yes to research, no to utilization? Medical, pharmacological and toxicological utilization of human embryonic stem cells from an ethical point of view].

    Science.gov (United States)

    Kress, H

    2008-09-01

    In exceptional cases, the German Stem Cell Act allows research on human embryonic stem cells. However, it does not allow the implementation of the research results if this in turn requires the use of further embryonic stem cell lines. It has, in the meantime, transpired that such research results could be of concrete use. Thus, in the distant future, it could be used in the clinical treatment of patients. Already in the nearer future the use of human embryonic stem cell lines can be envisaged for both the development and testing of medicines as well as in the field of toxicology. To this end, research concerning embryo toxicity and neurotoxicity is ground-breaking. The toxicological and pharmacological use of human embryonic stem cell lines should serve the protection of human health as well as the safe and reliable use of medicines. In addition, animal experiments could be reduced, which is desirable from a point of view of animal protection ethics. Since research on human embryonic stem cell lines is actually permitted in Germany, the use of the respective research results should be allowed all the more. This follows from the basic human right to health protection and health care. Legal ambiguities, which still exist in this respect, should be removed.

  18. The bad apple effect and social value orientation in public-goods dilemmas: replication and extension of research findings.

    Science.gov (United States)

    Wu, Song; Sun, Jiaqing; Cai, Wei; Jin, Shenghua

    2014-06-01

    Two studies were conducted to replicate and extend previous findings on the effect of uncooperative behavior on group cooperation (the "bad apple" effect). Study 1 (56 women, 40 men; M age = 23.5 yr.) manipulated information about contributions from the bad apple, controlling for overall contributions to a group account. Study 2 (50 women, 34 men; M age = 20.4 yr.) compared the effects of a bad apple and a good apple on cooperation. The social value orientation of participants was measured to explore individual differences in the bad apple effect. The results revealed a bad apple (a) decreased cooperation among individuals with proself and prosocial orientations in Study 1, and (b) had a greater effect than a good apple on those who were proself compared to prosocial in Study 2.

  19. Searching for sex- and gender-sensitive tuberculosis research in public health: finding a needle in a haystack

    Directory of Open Access Journals (Sweden)

    Vissandjee B

    2016-12-01

    Full Text Available Bilkis Vissandjee,1 Assia Mourid,2 Christina A Greenaway,3 Wendy E Short,4 Jodi A Proctor5 1Faculty of Nursing, Public Health Research Institute, Université de Montréal, Montréal, Montréal, QC, Canada; 2Allied Health Library, Université de Montréal, Montréal, QC, Canada; 3Department of Medicine, McGill University, Division of Infectious Diseases, Jewish General Hospital, Montréal, QC, Canada; 4Faculty of Humanities and Social Sciences, School of Social Sciences, University of Queensland, St Lucia, QLD, Australia; 5School of Social Work, McGill University, Montréal, QC, Canada Abstract: Despite broadening consideration of sex- and gender-based issues in health research, when seeking information on how sex and gender contribute to disease contexts for specific health or public health topics, a lack of consistent or systematic use of terminology in health literature means that it remains difficult to identify research with a sex or gender focus. These inconsistencies are driven, in part, by the complexity and terminological inflexibility of the indexing systems for gender- and sex-related terms in public health databases. Compounding the issue are authors’ diverse vocabularies, and in some cases lack of accuracy in defining and using fundamental sex–gender terms in writing, and when establishing keyword lists and search criteria. Considering the specific case of the tuberculosis (TB prevention and management literature, an analysis of sex and gender sensitivity in three health databases was performed. While there is an expanding literature exploring the roles of both sex and gender in the trajectory and lived experience of TB, we demonstrate the potential to miss relevant research when attempting to retrieve literature using only the search criteria currently available. We, therefore, argue that for good clinical practice to be achieved; there is a need for both public health researchers and users to be better educated in appropriate

  20. The TIMSS Videotape Classroom Study: Methods and Findings from an Exploratory Research Project on Eighth-Grade Mathematics Instruction in Germany, Japan, and the United States.

    Science.gov (United States)

    Stigler, James W.; Gonzales, Patrick; Kawanaka, Takako; Knoll, Steffen; Serrano, Ana

    1999-01-01

    Describes the methods and preliminary findings of the Videotape Classroom Study, a video survey of eighth-grade mathematics lessons in Germany, Japan, and the United States. Part of the Third International Mathematics and Science study, this research project is the first study of videotaped records from national probability samples. (SLD)

  1. Evaluating the Development of Chemistry Undergraduate Researchers' Scientific Thinking Skills Using Performance-Data: First Findings from the Performance Assessment of Undergraduate Research (PURE) Instrument

    Science.gov (United States)

    Harsh, Joseph; Esteb, John J.; Maltese, Adam V.

    2017-01-01

    National calls in science, technology, engineering, and technology education reform efforts have advanced the wide-scale engagement of students in undergraduate research for the preparation of a workforce and citizenry able to attend to the challenges of the 21st century. Awareness of the potential benefits and costs of these experiences has led…

  2. Effects of capturing and collaring on polar bears: findings from long-term research on the southern Beaufort Sea population

    Science.gov (United States)

    Rode, Karyn D.; Pagano, Anthony M.; Bromaghin, Jeffrey F.; Atwood, Todd C.; Durner, George M.; Simac, Kristin S.; Amstrup, Steven C.

    2014-01-01

    Context: The potential for research methods to affect wildlife is an increasing concern among both scientists and the public. This topic has a particular urgency for polar bears because additional research is needed to monitor and understand population responses to rapid loss of sea ice habitat.Aims: This study used data collected from polar bears sampled in the Alaska portion of the southern Beaufort Sea to investigate the potential for capture to adversely affect behaviour and vital rates. We evaluated the extent to which capture, collaring and handling may influence activity and movement days to weeks post-capture, and body mass, body condition, reproduction and survival over 6 months or more.Methods: We compared post-capture activity and movement rates, and relationships between prior capture history and body mass, body condition and reproductive success. We also summarised data on capture-related mortality.Key results: Individual-based estimates of activity and movement rates reached near-normal levels within 2–3 days and fully normal levels within 5 days post-capture. Models of activity and movement rates among all bears had poor fit, but suggested potential for prolonged, lower-level rate reductions. Repeated captures was not related to negative effects on body condition, reproduction or cub growth or survival. Capture-related mortality was substantially reduced after 1986, when immobilisation drugs were changed, with only 3 mortalities in 2517 captures from 1987–2013.Conclusions: Polar bears in the southern Beaufort Sea exhibited the greatest reductions in activity and movement rates 3.5 days post-capture. These shorter-term, post-capture effects do not appear to have translated into any long-term effects on body condition, reproduction, or cub survival. Additionally, collaring had no effect on polar bear recovery rates, body condition, reproduction or cub survival.Implications: This study provides empirical evidence that current capture

  3. Preventative lipid-based nutrient supplements (LNS) and young child feeding practices: findings from qualitative research in Haiti.

    Science.gov (United States)

    Lesorogol, Carolyn; Jean-Louis, Sherlie; Green, Jamie; Iannotti, Lora

    2015-12-01

    To prevent undernutrition in an urban slum in Haiti, a lipid-based nutrient supplement (LNS) was introduced through a randomised control trial. Food supplementation for young child nutrition has a long history in Haiti, but there is little empirical information regarding the effects of supplementation on young child feeding practices. One of the concerns raised by supplementation is that it may disrupt other positive feeding practices such as breastfeeding and use of other complementary foods, with negative consequences for child nutrition. We conducted 29 in-depth interviews with mother-baby pairs from the three comparison groups: control, 3-month LNS supplementation and 6-month LNS supplementation. Findings from those in the LNS groups indicated high acceptance and satisfaction with LNS and perceptions that it positively affects child health and development. LNS was integrated into and enhanced ongoing complementary feeding practices. The effects of LNS use on duration and perceived quantity of breastfeeding were variable, but generally, breastfeeding was maintained during and after the intervention. Interviews generated insights into beliefs regarding infant and young child feeding practices such as introduction and use of complementary foods, and breastfeeding duration, exclusivity and cessation. Implications for the use of LNS in public health nutrition programmes are discussed. © 2014 John Wiley & Sons Ltd.

  4. Family Pet Ownership during Childhood: Findings from a UK Birth Cohort and Implications for Public Health Research

    Science.gov (United States)

    Westgarth, Carri; Heron, Jon; Ness, Andy R.; Bundred, Peter; Gaskell, Rosalind M.; Coyne, Karen P.; German, Alexander J.; McCune, Sandra; Dawson, Susan

    2010-01-01

    In developed nations, approximately half of household environments contain pets. Studies of Human-Animal Interaction (HAI) have proposed that there are health benefits and risks associated with pet ownership. However, accurately demonstrating and understanding these relationships first requires a better knowledge of factors associated with ownership of different pet types. A UK birth cohort, the Avon Longitudinal Study of Parents and Children (ALSPAC), were used to collect pet ownership data from the mothers, from gestation to child age 10 years old. 14,663 children were included in the study, of which mothers of 13,557 reported pet information at gestation, and 7,800 by age 10. Pet types recorded include cat, dog, rabbit, rodent, bird, fish and tortoise/turtle. The dataset also contains a number of demographic, socioeconomic and behavioural variables relevant to human health behaviour. Logistic regression was used to build multivariable models for ownership of each pet type at age 7 years. Family pet ownership increased during childhood, in particular rabbits, rodents and fish. A number of socioeconomic and demographic factors were associated with ownership of different pet types and the effects differed depending on the pet type studied. Variables which require consideration by researchers include gender, presence of older siblings, ethnicity, maternal and paternal education, maternal and paternal social class, maternal age, number of people in the household, house type, and concurrent ownership of other pets. Whether the mother had pets during her childhood was a strong predictor of pet ownership in all models. In HAI studies, care should be taken to control for confounding factors, and to treat each pet type individually. ALSPAC and other similar birth cohorts can be considered a potential resource for research into the effects of pet ownership during childhood. PMID:21139856

  5. Family Pet Ownership during Childhood: Findings from a UK Birth Cohort and Implications for Public Health Research

    Directory of Open Access Journals (Sweden)

    Jon Heron

    2010-10-01

    Full Text Available In developed nations, approximately half of household environments contain pets. Studies of Human-Animal Interaction (HAI have proposed that there are health benefits and risks associated with pet ownership. However, accurately demonstrating and understanding these relationships first requires a better knowledge of factors associated with ownership of different pet types. A UK birth cohort, the Avon Longitudinal Study of Parents and Children (ALSPAC, were used to collect pet ownership data from the mothers, from gestation to child age 10 years old. 14,663 children were included in the study, of which mothers of 13,557 reported pet information at gestation, and 7,800 by age 10. Pet types recorded include cat, dog, rabbit, rodent, bird, fish and tortoise/turtle. The dataset also contains a number of demographic, socioeconomic and behavioural variables relevant to human health behaviour. Logistic regression was used to build multivariable models for ownership of each pet type at age 7 years. Family pet ownership increased during childhood, in particular rabbits, rodents and fish. A number of socioeconomic and demographic factors were associated with ownership of different pet types and the effects differed depending on the pet type studied. Variables which require consideration by researchers include gender, presence of older siblings, ethnicity, maternal and paternal education, maternal and paternal social class, maternal age, number of people in the household, house type, and concurrent ownership of other pets. Whether the mother had pets during her childhood was a strong predictor of pet ownership in all models. In HAI studies, care should be taken to control for confounding factors, and to treat each pet type individually. ALSPAC and other similar birth cohorts can be considered a potential resource for research into the effects of pet ownership during childhood.

  6. Informing a Behavior Change Communication Strategy: Formative Research Findings From the Scaling Up Nutrition Movement in Mozambique.

    Science.gov (United States)

    Kodish, Stephen; Aburto, Nancy; Dibari, Filippo; Brieger, William; Agostinho, Saozinha P; Gittelsohn, Joel

    2015-09-01

    Nutrition interventions targeting the first 1000 days show promise to improve nutritional status, but they require effective implementation. Formative research is thus invaluable for developing such interventions, but there have been few detailed studies that describe this phase of work within the Scaling Up Nutrition (SUN) movement. To inform a stunting prevention intervention in Cabo Delgado, Mozambique, by describing the sociocultural landscape and elucidating characteristics related to young child food, illness, and health. This formative research utilized a rapid assessment procedures (RAP) approach with 3 iterative phases that explored local perceptions and behaviors around food and illness among the Macua, Mwani, and Maconde ethnic groups. Ethnographic methods, including in-depth interviews, direct observations, free lists, and pile sorts, were used to collect data from community leaders, caregivers, and children 6 to 23 months. Data were analyzed drawing from grounded theory and cultural domain analysis. Geographic differences drive sociocultural characteristics amid 3 ethnic groups that allow for segmentation of the population into 2 distinct audiences for behavior change communications. These 2 communities have similar classification systems for children's foods but different adult dietary patterns. Small-quantity lipid-based nutrient supplement did not fall into the existing food classification systems of either community, and participants preferred its promotion through community leader channels. Community members in both groups have little recognition of and perceived severity toward nutrition-related illnesses. Within Cabo Delgado, the cultural heterogeneity yields substantial differences related to food, illness, and health that are necessary to consider for developing an effective nutrition intervention. © The Author(s) 2015.

  7. Fixed Points

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 5; Issue 5. Fixed Points - From Russia with Love - A Primer of Fixed Point Theory. A K Vijaykumar. Book Review Volume 5 Issue 5 May 2000 pp 101-102. Fulltext. Click here to view fulltext PDF. Permanent link:

  8. Tipping Point

    Medline Plus

    Full Text Available ... OnSafety CPSC Stands for Safety The Tipping Point Home > 60 Seconds of Safety (Videos) > The Tipping Point ... 24 hours a day. For young children whose home is a playground, it’s the best way to ...

  9. Tipping Point

    Medline Plus

    Full Text Available ... 60 Seconds of Safety (Videos) > The Tipping Point The Tipping Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture head injury product safety television tipover tv Watch the video in Adobe Flash ...

  10. Publication of statistically significant research findings in prosthodontics & implant dentistry in the context of other dental specialties.

    Science.gov (United States)

    Papageorgiou, Spyridon N; Kloukos, Dimitrios; Petridis, Haralampos; Pandis, Nikolaos

    2015-10-01

    To assess the hypothesis that there is excessive reporting of statistically significant studies published in prosthodontic and implantology journals, which could indicate selective publication. The last 30 issues of 9 journals in prosthodontics and implant dentistry were hand-searched for articles with statistical analyses. The percentages of significant and non-significant results were tabulated by parameter of interest. Univariable/multivariable logistic regression analyses were applied to identify possible predictors of reporting statistically significance findings. The results of this study were compared with similar studies in dentistry with random-effects meta-analyses. From the 2323 included studies 71% of them reported statistically significant results, with the significant results ranging from 47% to 86%. Multivariable modeling identified that geographical area and involvement of statistician were predictors of statistically significant results. Compared to interventional studies, the odds that in vitro and observational studies would report statistically significant results was increased by 1.20 times (OR: 2.20, 95% CI: 1.66-2.92) and 0.35 times (OR: 1.35, 95% CI: 1.05-1.73), respectively. The probability of statistically significant results from randomized controlled trials was significantly lower compared to various study designs (difference: 30%, 95% CI: 11-49%). Likewise the probability of statistically significant results in prosthodontics and implant dentistry was lower compared to other dental specialties, but this result did not reach statistical significant (P>0.05). The majority of studies identified in the fields of prosthodontics and implant dentistry presented statistically significant results. The same trend existed in publications of other specialties in dentistry. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Comparative effectiveness research in DARTNet primary care practices: point of care data collection on hypoglycemia and over-the-counter and herbal use among patients diagnosed with diabetes.

    Science.gov (United States)

    Libby, Anne M; Pace, Wilson; Bryan, Cathy; Anderson, Heather Orton; Ellis, Samuel L; Allen, Richard Read; Brandt, Elias; Huebschmann, Amy G; West, David; Valuck, Robert J

    2010-06-01

    The Distributed Ambulatory Research in Therapeutics Network (DARTNet) is a federated network of electronic health record (EHR) data, designed as a platform for next-generation comparative effectiveness research in real-world settings. DARTNet links information from nonintegrated primary care clinics that use EHRs to deliver ambulatory care to overcome limitations with traditional observational research. Test the ability to conduct a remote, electronic point of care study in DARTNet practices by prompting clinic staff to obtain specific information during a patient encounter. Prospective survey of patients identified through queries of clinical data repositories in federated network organizations. On patient visit, survey is triggered and data are relinked to the EHR, de-identified, and copied for evaluation. Adult patients diagnosed with diabetes mellitus that scheduled a clinic visit for any reason in a 2-week period in DARTNet primary care practices. Survey on hypoglycemic events (past month) and over-the-counter and herbal supplement use. DARTNet facilitated point of care data collection triggered by an electronic prompt for additional information at a patient visit. More than one-third of respondents (33% response rate) reported either mild (45%) or severe hypoglycemic events (5%) in the month before the survey; only 3 of those were also coded using the ICD-9 (a significant difference in detection rates 37% vs. 1%). Nearly one-quarter of patients reported taking an OTC/herbal, 4% specifically for the treatment of symptoms of diabetes. Prospective data collection is feasible in DARTNet and can enable comparative effectiveness and safety research.

  12. Concordance between patient satisfaction and the dentist’s view: findings from the National Dental Practice-Based Research Network

    Science.gov (United States)

    Riley, Joseph L.; Hudak-Boss, Susan; Fellows, Jeffery L.; Rindal, Brad; Gilbert, Gregg H.

    2014-01-01

    Objectives This study examined the dentist’s view of the patient’s experience and concordance with the patient’s rating of satisfaction. Methods Practitioners from 197 practices in the National Dental Practice-Based Research Network recruited consecutively seen patients who had defective restorations that were replaced or repaired. At the end of the treatment visit, the treating dentist and 5,879 patients completed and returned a survey that asked about the patient’s satisfaction. Results Dentists viewed their patients as satisfied with their treatment experience (89% n=4,719) and that they had been perceived as friendly (97%, n=5,136). Dentists had less strong feelings about whether patients had a preference for the restorative material (43%, n=2,271) or an interest in information about the procedure (33%, n=1,757). Overall, patients were satisfied, and most of the time dentists correctly predicted this. Among patients who were less than satisfied, there was a substantial subset of cases where dentists were not aware. Conclusion For improved patient-centered care, patient desires, expectations and perception of the dental care experience need to be assessed by the dentist and then managed or corrected as needed. Practice implications By taking a patient-centered approach, dentists should seek to understand how patients evaluate and rate the service provided, thereby enabling themselves to focus on what each patient values most. PMID:24686969

  13. Impacts of reintroduced bison on first nations people in Yukon, Canada: Finding common ground through participatory research and social learning

    Directory of Open Access Journals (Sweden)

    Douglas A Clark

    2016-01-01

    Full Text Available From 1988-1992 wood bison (Bison bison athabascae were transplanted to the southwest Yukon, inadvertently creating concerns among local First Nations about their impacts on other wildlife, habitat, and their members' traditional livelihoods. To understand these concerns we conducted a participatory impact assessment based on a multistage analysis of existing and new qualitative data. We found wood bison had since become a valued food resource, though there was a socially-determined carrying capacity for this population. Study participants desire a population large enough to sustainably harvest but avoid crossing a threshold beyond which bison may alter the regional ecosystem. An alternative problem definition emerged that focuses on how wildlife and people alike are adapting to the observed long-term changes in climate and landscape; suggesting that a wider range of acceptable policy alternatives likely exists than may have previously been thought. Collective identification of this new problem definition indicates that this specific assessment acted as a social learning process in which the participants jointly discovered new perspectives on a problem at both individual and organisational levels. Subsequent regulatory changes, based on this research, demonstrate the efficacy of participatory impact assessment for ameliorating human-wildlife conflicts.

  14. Family conflict, emotional security, and child development: translating research findings into a prevention program for community families.

    Science.gov (United States)

    Cummings, E Mark; Schatz, Julie N

    2012-03-01

    The social problem posed by family conflict to the physical and psychological health and well-being of children, parents, and underlying family relationships is a cause for concern. Inter-parental and parent-child conflict are linked with children's behavioral, emotional, social, academic, and health problems, with children's risk particularly elevated in distressed marriages. Supported by the promise of brief psycho-educational programs (e.g., Halford et al. in Journal of Family Psychology 22:497-505, 2008; Sanders in Journal of Family Psychology 22:506-517, 2008), the present paper presents the development and evaluation of a prevention program for community families with children, concerned with family-wide conflict and relationships, and building on Emotional Security Theory (Davies and Cummings in Psychological Bulletin 116:387-411, 1994). This program uniquely focuses on translating research and theory in this area into brief, engaging programs for community families to improve conflict and emotional security for the sake of the children. Evaluation is based on multi-domain and multi-method assessments of family-wide and child outcomes in the context of a randomized control design. A series of studies are briefly described in the programmatic development of a prevention program for conflict and emotional security for community families, culminating in a program for family-wide conflict and emotional security for families with adolescents. With regard to this ongoing program, evidence is presented at the post-test for improvements in family-wide functioning, consideration of the relative benefits for different groups within the community, and preliminary support for the theoretical bases for program outcomes.

  15. Dentist Material Selection for Single-Unit Crowns: Findings from The National Dental Practice-Based Research Network

    Science.gov (United States)

    Makhija, Sonia K.; Lawson, Nathaniel C.; Gilbert, Gregg H.; Litaker, Mark S.; McClelland, Jocelyn A.; Louis, David R.; Gordan, Valeria V.; Pihlstrom, Daniel J.; Meyerowitz, Cyril; Mungia, Rahma; McCracken, Michael S.

    2016-01-01

    Objectives Dentists enrolled in the National Dental Practice-Based Research Network completed a study questionnaire about techniques and materials used for single-unit crowns and an enrollment questionnaire about dentist/practice characteristics. The objectives were to quantify dentists’ material recommendations and test the hypothesis that dentist’s and practice’s characteristics are significantly associated with these recommendations. Methods Surveyed dentists responded to a contextual scenario asking what material they would use for a single-unit crown on an anterior and posterior tooth. Material choices included: full metal, porcelain-fused-to-metal (PFM), all-zirconia, layered zirconia, lithium disilicate, leucite-reinforced ceramic, or other. Results 1,777 of 2,132 eligible dentists responded (83%). The top 3 choices for anterior crowns were lithium disilicate (54%), layered zirconia (17%), and leucite-reinforced glass ceramic (13%). There were significant differences (p<0.05) by dentist’s gender, race, years since graduation, practice type, region, practice busyness, hours worked/week, and location type. The top 3 choices for posterior crowns were all-zirconia (32%), PFM (31%), and lithium disilicate (21%). There were significant differences (p<0.05) by dentist’s gender, practice type, region, practice busyness, insurance coverage, hours worked/week, and location type. Conclusions Network dentists use a broad range of materials for single-unit crowns for anterior and posterior teeth, adopting newer materials into their practices as they become available. Material choices are significantly associated with dentist’s and practice’s characteristics. Clinical Significance Decisions for crown material may be influenced by factors unrelated to tooth and patient variables. Dentists should be cognizant of this when developing an evidence-based approach to selecting crown material. PMID:27693778

  16. Treatment Recommendations for Single-Unit Crowns: Findings from The National Dental Practice-Based Research Network

    Science.gov (United States)

    McCracken, Michael S.; Louis, David R.; Litaker, Mark S.; Minyé, Helena M.; Mungia, Rahma; Gordan, Valeria V.; Marshall, Don G.; Gilbert, Gregg H.

    2016-01-01

    Background Objectives were to: (1) quantify practitioner variation in likelihood to recommend a crown; and (2) test whether certain dentist, practice, and clinical factors are significantly associated with this likelihood. Methods Dentists in the National Dental Practice-Based Research Network completed a questionnaire about indications for single-unit crowns. In four clinical scenarios, practitioners ranked their likelihood of recommending a single-unit crown. These responses were used to calculate a dentist-specific “Crown Factor” (CF; range 0–12). A higher score implies a higher likelihood to recommend a crown. Certain characteristics were tested for statistically significant associations with the CF. Results 1,777 of 2,132 eligible dentists responded (83%). Practitioners were most likely to recommend crowns for teeth that were fractured, cracked, endodontically-treated, or had a broken restoration. Practitioners overwhelmingly recommended crowns for posterior teeth treated endodontically (94%). Practice owners, Southwest practitioners, and practitioners with a balanced work load were more likely to recommend crowns, as were practitioners who use optical scanners for digital impressions. Conclusions There is substantial variation in the likelihood of recommending a crown. While consensus exists in some areas (posterior endodontic treatment), variation dominates in others (size of an existing restoration). Recommendations varied by type of practice, network region, practice busyness, patient insurance status, and use of optical scanners. Practical Implications Recommendations for crowns may be influenced by factors unrelated to tooth and patient variables. A concern for tooth fracture -- whether from endodontic treatment, fractured teeth, or large restorations -- prompted many clinicians to recommend crowns. PMID:27492046

  17. Use of caries-preventive agents in children: findings from the dental practice-based research network.

    Science.gov (United States)

    Riley, J L; Richman, Joshua S; Rindal, D Brad; Fellows, Jeffrey L; Qvist, Vibeke; Gilbert, Gregg H; Gordan, Valeria V

    2010-01-01

    Scientific evidence supports the application of caries-preventive agents in children and adolescents, and this knowledge must be applied to the practice of dentistry. There are few multi-region data that allow for comparisons of practice patterns between types of dental practices and geographical regions. The objective of the present study was to characterise the use of specific caries-preventive agents for paediatric patients in a large multi-region sample of practising clinicians. The present study surveyed clinicians from the Dental Practice-based Research Network who perform restorative dentistry in their practices. The survey consisted of a questionnaire that presented a range of questions about caries risk assessment and the use of preventive techniques in children aged 6 to 18 years. Dental sealants (69%) or in-office fluoride (82%) were the most commonly used caries-preventive agents of the caries preventive regimens. The recommendation of at-home caries-preventive agents ranged from 36% to 7%,with the most commonly used agent being non-prescription fluoride rinse. Clinicians who practised in a large group practice model and clinicians who come from the Scandinavian region use caries risk assessment more frequently compared to clinicians who come from regions that had, predominantly, clinicians in private practice. Whether or not clinicians used caries risk assessment with their paediatric patients was poorly correlated with the likelihood of actually using caries-preventive treatments on patients. Although clinicians reported the use of some form of in-office caries-preventive agent, there was considerable variability across practices. These differences could represent a lack of consensus across practising clinicians about the benefits of caries-preventive agents, or a function of differing financial incentives, or patient pools with differing levels of overall caries risk.

  18. The incidence of eating disorders in the UK in 2000-2009: findings from the General Practice Research Database.

    Science.gov (United States)

    Micali, Nadia; Hagberg, Katrina W; Petersen, Irene; Treasure, Janet L

    2013-05-28

    Few studies have investigated the incidence of eating disorders (EDs). Important questions about changes in the incidence of diagnosed disorders in recent years, disorder and gender-specific onset and case detection remain unanswered. Understanding changes in incidence is important for public health, clinical practice and service provision. The aim of this study was to estimate the annual (age-specific, gender-specific and subtype-specific) incidence of diagnosed ED: anorexia nervosa (AN), bulimia nervosa (BN) and eating disorder not otherwise specified (EDNOS) in primary care over a 10-year period in the UK (2000-2009); to examine the changes within the study period; and to describe peak age at diagnosis. Register-based study. Primary care. Data were obtained from a primary care register, the General Practice Research Database, which contains anonymised records representing about 5% of the UK population. All patients with a first-time diagnosis of AN, BN and EDNOS were identified. Annual crude and age-standardised incidence rates were calculated. A total of 9072 patients with a first-time diagnosis of an ED were identified. The age-standardised annual incidence rate of all diagnosed ED for ages 10-49 increased from 32.3 (95% CI 31.7 to 32.9) to 37.2 (95% CI 36.6 to 37.9) per 100 000 between 2000 and 2009. The incidence of AN and BN was stable; however, the incidence of EDNOS increased. The incidence of the diagnosed ED was highest for girls aged 15-19 and for boys aged 10-14. The age-standardised incidence of ED increased in primary care between 2000 and 2009. New diagnoses of EDNOS increased, and EDNOS is the most common ED in primary care.

  19. The incidence of eating disorders in the UK in 2000–2009: findings from the General Practice Research Database

    Science.gov (United States)

    Micali, Nadia; Hagberg, Katrina W; Petersen, Irene; Treasure, Janet L

    2013-01-01

    Objectives Few studies have investigated the incidence of eating disorders (EDs). Important questions about changes in the incidence of diagnosed disorders in recent years, disorder and gender-specific onset and case detection remain unanswered. Understanding changes in incidence is important for public health, clinical practice and service provision. The aim of this study was to estimate the annual (age-specific, gender-specific and subtype-specific) incidence of diagnosed ED: anorexia nervosa (AN), bulimia nervosa (BN) and eating disorder not otherwise specified (EDNOS) in primary care over a 10-year period in the UK (2000–2009); to examine the changes within the study period; and to describe peak age at diagnosis. Design Register-based study. Setting Primary care. Data were obtained from a primary care register, the General Practice Research Database, which contains anonymised records representing about 5% of the UK population. Participants All patients with a first-time diagnosis of AN, BN and EDNOS were identified. Primary outcome Annual crude and age-standardised incidence rates were calculated. Results A total of 9072 patients with a first-time diagnosis of an ED were identified. The age-standardised annual incidence rate of all diagnosed ED for ages 10–49 increased from 32.3 (95% CI 31.7 to 32.9) to 37.2 (95% CI 36.6 to 37.9) per 100 000 between 2000 and 2009. The incidence of AN and BN was stable; however, the incidence of EDNOS increased. The incidence of the diagnosed ED was highest for girls aged 15–19 and for boys aged 10–14. Conclusions The age-standardised incidence of ED increased in primary care between 2000 and 2009. New diagnoses of EDNOS increased, and EDNOS is the most common ED in primary care. PMID:23793681

  20. Correlation between symptoms and external characteristics of cracked teeth: Findings from The National Dental Practice-Based Research Network.

    Science.gov (United States)

    Hilton, Thomas J; Funkhouser, Ellen; Ferracane, Jack L; Gilbert, Gregg H; Baltuck, Camille; Benjamin, Paul; Louis, David; Mungia, Rahma; Meyerowitz, Cyril

    2017-04-01

    Cracked teeth are ubiquitous in the adult dentition. The objective of this study was to determine which patient traits and behaviors and external tooth and crack characteristics correlate with cracked teeth being symptomatic. Dentists in The National Dental Practice-Based Research Network enrolled a convenience sample of patients each with a single, vital posterior tooth with at least 1 observable external crack in this observational study; they enrolled 2,975 cracked teeth from 209 practitioners. The authors collected data at the patient level, tooth level, and crack level. They used generalized estimating equations to obtain significant (P crack. Characteristics positively associated with cracked tooth symptoms, after adjusting for demographics, included patients who clenched, ground, or pressed their teeth together (OR, 1.30; 95% confidence interval [CI], 1.12-1.50), molars (OR, 1.58; 95% CI, 1.30-1.92), teeth with a wear facet through enamel (OR, 1.22; 95% CI, 1.01-1.40), carious lesions (OR, 1.31; 95% CI, 1.07-1.60), cracks that were on the distal surface of the tooth (OR, 1.31; 95% CI, 1.13-1.52), and cracks that blocked transilluminated light (OR, 1.31, 95% CI, 1.09-1.57). Teeth with stained cracks were negatively associated with having cracked tooth symptoms (OR, 0.68; 95% CI, 0.55-0.84). The greatest likelihood of a cracked tooth being symptomatic was found when patients reported clenching or grinding their teeth and had a molar with a distal crack that blocked transilluminated light. This information can help inform dentists in the decision-making process regarding the prognosis for a cracked tooth. Copyright © 2017 American Dental Association. Published by Elsevier Inc. All rights reserved.

  1. Tuberculosis Case Finding With Combined Rapid Point-of-Care Assays (Xpert MTB/RIF and Determine TB LAM) in HIV-Positive Individuals Starting Antiretroviral Therapy in Mozambique.

    Science.gov (United States)

    Floridia, Marco; Ciccacci, Fausto; Andreotti, Mauro; Hassane, Archa; Sidumo, Zita; Magid, Nurja A; Sotomane, Horacio; David, Muhlavasse; Mutemba, Elsa; Cebola, Junia; Mugunhe, Remigio Josè; Riccardi, Fabio; Marazzi, Maria Cristina; Giuliano, Marina; Palombi, Leonardo; Mancinelli, Sandro

    2017-11-13

    Tuberculosis is a major health concern in several countries, and effective diagnostic algorithms for use in human immunodeficiency virus (HIV)-positive patients are urgently needed. At prescription of antiretroviral therapy, all patients in 3 Mozambican health centers were screened for tuberculosis, with a combined approach: World Health Organization (WHO) 4-symptom screening (fever, cough, night sweats, and weight loss), a rapid test detecting mycobacterial lipoarabinomannan in urine (Determine TB LAM), and a molecular assay performed on a sputum sample (Xpert MTB/RIF; repeated if first result was negative). Patients with positive LAM or Xpert MTB/RIF results were referred for tuberculosis treatment. Among 972 patients with a complete diagnostic algorithm (58.5% female; median CD4 cell count, 278/μL; WHO HIV stage I, 66.8%), 98 (10.1%) tested positive with Xpert (90, 9.3%) or LAM (34, 3.5%) assays. Compared with a single-test Xpert strategy, dual Xpert tests improved case finding by 21.6%, LAM testing alone improved it by 13.5%, and dual Xpert tests plus LAM testing improved it by 32.4%. Rifampicin resistance in Xpert-positive patients was infrequent (2.5%). Among patients with positive results, 22 of 98 (22.4%) had no symptoms at WHO 4-symptom screening. Patients with tuberculosis diagnosed had significantly lower CD4 cell counts and hemoglobin levels, more advanced WHO stage, and higher HIV RNA levels. Fifteen (15.3%) did not start tuberculosis treatment, mostly owing to rapidly deteriorating clinical conditions or logistical constraints. The median interval between start of the diagnostic algorithm and start of tuberculosis treatment was 7 days. The prevalence of tuberculosis among Mozambican HIV-positive patients starting antiretroviral therapy was 10%, with limited rifampicin resistance. Use of combined point-of-care tests increased case finding, with a short time to treatment. Interventions are needed to remove logistical barriers and prevent presentation

  2. The Impact of Personality Factors and Preceding User Comments on the Processing of Research Findings on Deep Brain Stimulation: A Randomized Controlled Experiment in a Simulated Online Forum.

    Science.gov (United States)

    Feinkohl, Insa; Flemming, Danny; Cress, Ulrike; Kimmerle, Joachim

    2016-03-03

    Laypeople frequently discuss medical research findings on Web-based platforms, but little is known about whether they grasp the tentativeness that is inherent in these findings. Potential influential factors involved in understanding medical tentativeness have hardly been assessed to date. The research presented here aimed to examine the effects of personality factors and of other users' previous contributions in a Web-based forum on laypeople's understanding of the tentativeness of medical research findings, using the example of research on deep brain stimulation. We presented 70 university students with an online news article that reported findings on applying deep brain stimulation as a novel therapeutic method for depression, which participants were unfamiliar with. In a randomized controlled experiment, we manipulated the forum such that the article was either accompanied by user comments that addressed the issue of tentativeness, by comments that did not address this issue, or the article was accompanied by no comments at all. Participants were instructed to write their own individual user comments. Their scientific literacy, epistemological beliefs, and academic self-efficacy were measured. The outcomes measured were perceived tentativeness and tentativeness addressed in the participants' own comments. More sophisticated epistemological beliefs enhanced the perception of tentativeness (standardized β=.26, P=.034). Greater scientific literacy (stand. β=.25, P=.025) and greater academic self-efficacy (stand. β=.31, P=.007) were both predictors of a more extensive discussion of tentativeness in participants' comments. When forum posts presented in the experiment addressed the issue of tentativeness, participants' subsequent behavior tended to be consistent with what they had read in the forum, F2,63=3.66; P=.049, ηp(2)=.092. Students' understanding of the tentativeness of research findings on deep brain stimulation in an online forum is influenced by a

  3. Dew Point

    OpenAIRE

    Goldsmith, Shelly

    1999-01-01

    Dew Point was a solo exhibition originating at PriceWaterhouseCoopers Headquarters Gallery, London, UK and toured to the Centre de Documentacio i Museu Textil, Terrassa, Spain and Gallery Aoyama, Tokyo, Japan.

  4. Tipping Point

    Medline Plus

    Full Text Available ... Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture head injury product safety television tipover tv Watch the video in Adobe Flash ...

  5. Tipping Point

    Science.gov (United States)

    ... Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture head injury product safety television tipover tv Watch the video in Adobe Flash ...

  6. Tipping Point

    Medline Plus

    Full Text Available ... Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture head ... see news reports about horrible accidents involving young children and furniture, appliance and tv tip-overs. The ...

  7. Tipping Point

    Medline Plus

    Full Text Available ... Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture head ... TV falls with about the same force as child falling from the third story of a building. ...

  8. Tipping Point

    Medline Plus

    Full Text Available ... Tipping Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture ... about horrible accidents involving young children and furniture, appliance and tv tip-overs. The force of a ...

  9. The simulation research of dissolved nitrogen and phosphorus non-point source pollution in Xiao-Jiang watershed of Three Gorges Reservoir area.

    Science.gov (United States)

    Wu, Lei; Long, Tian-Yu; Li, Chong-Ming

    2010-01-01

    Xiao-jiang, with a basin area of almost 5,276 km(2) and a length of 182.4 km, is located in the center of the Three Gorges Reservoir Area, and is the largest tributary of the central section in Three Gorges Reservoir Area, farmland accounts for a large proportion of Xiao-jiang watershed, and the hilly cropland of purple soil is much of the farmland of the watershed. After the second phase of water storage in the Three Gorges Reservoir, the majority of sub-rivers in the reservoir area experienced eutrophication phenomenon frequently, and non-point source (NPS) pollution has become an important source of pollution in Xiao-jiang Watershed. Because dissolved nitrogen and phosphorus non-point source pollution are related to surface runoff and interflow, using climatic, topographic and land cover data from the internet and research institutes, the Semi-Distributed Land-use Runoff Process (SLURP) hydrological model was introduced to simulate the complete hydrological cycle of the Xiao-jiang Watershed. Based on the SLURP distributed hydrological model, non-point source pollution annual output load models of land use and rural residents were respectively established. Therefore, using GIS technology, considering the losses of dissolved nitrogen and phosphorus in the course of transport, a dissolved non-point source pollution load dynamic model was established by the organic coupling of the SLURP hydrological model and land-use output model. Through the above dynamic model, the annual dissolved non-point source nitrogen and phosphorus pollution output as well as the load in different types were simulated and quantitatively estimated from 2001 to 2008, furthermore, the loads of Xiao-jiang Watershed were calculated and expressed by temporal and spatial distribution in the Three Gorges Reservoir Area. The simulation results show that: the temporal changes of dissolved nitrogen and phosphorus load in the watershed are close to the inter-annual changes of rainfall runoff, and the

  10. Associations between use of crack cocaine and HIV-1 disease progression: research findings and implications for mother-to-infant transmission

    OpenAIRE

    Cook, Judith A.

    2011-01-01

    Recent in vitro and in vivo research has suggested that cocaine has a direct effect on the pathogenesis of AIDS. These findings are confirmed by epidemiological studies linking the use of injected, inhaled, and smoked (crack) cocaine and indicators of HIV disease progression, even among adherent users of highly active antiretroviral therapy. Recent studies of vertical HIV transmission suggest that cocaine use may play a role in mother-to-child infection via alteration of maternal immune respo...

  11. Point specificity in acupuncture

    Directory of Open Access Journals (Sweden)

    Choi Emma M

    2012-02-01

    Full Text Available Abstract The existence of point specificity in acupuncture is controversial, because many acupuncture studies using this principle to select control points have found that sham acupoints have similar effects to those of verum acupoints. Furthermore, the results of pain-related studies based on visual analogue scales have not supported the concept of point specificity. In contrast, hemodynamic, functional magnetic resonance imaging and neurophysiological studies evaluating the responses to stimulation of multiple points on the body surface have shown that point-specific actions are present. This review article focuses on clinical and laboratory studies supporting the existence of point specificity in acupuncture and also addresses studies that do not support this concept. Further research is needed to elucidate the point-specific actions of acupuncture.

  12. Iowa Geologic Sampling Points

    Data.gov (United States)

    Iowa State University GIS Support and Research Facility — Point locations of geologic samples/files in the IGS repository. Types of samples include well cuttings, outcrop samples, cores, drillers logs, measured sections,...

  13. The TIMSS Videotape Classroom Study: Methods and Findings from an Exploratory Research Project on Eighth-Grade Mathematics Instruction in Germany, Japan, and the United States. A Research and Development Report.

    Science.gov (United States)

    Stigler, James W.; Gonzales, Patrick; Kwanaka, Takako; Knoll, Steffen; Serrano, Ana

    This report presents the methods and preliminary findings of the Videotape Classroom Study, a video study of eighth-grade mathematics lessons in Germany, Japan, and the United States. This exploratory research project is part of the Third International Mathematics and Science Study (TIMSS). The study included 231 eighth-grade mathematics…

  14. Housing First for People With Severe Mental Illness Who Are Homeless: A Review of the Research and Findings From the At Home–Chez soi Demonstration Project

    Science.gov (United States)

    Aubry, Tim; Nelson, Geoffrey; Tsemberis, Sam

    2015-01-01

    Objective: To provide a review of the extant research literature on Housing First (HF) for people with severe mental illness (SMI) who are homeless and to describe the findings of the recently completed At Home (AH)–Chez soi (CS) demonstration project. HF represents a paradigm shift in the delivery of community mental health services, whereby people with SMI who are homeless are supported through assertive community treatment or intensive case management to move into regular housing. Method: The AH–CS demonstration project entailed a randomized controlled trial conducted in 5 Canadian cities between 2009 and 2013. Mixed methods were used to examine the implementation of HF programs and participant outcomes, comparing 1158 people receiving HF to 990 people receiving standard care. Results: Initial research conducted in the United States shows HF to be a promising approach, yielding superior outcomes in helping people to rapidly exit homelessness and establish stable housing. Findings from the AH–CS demonstration project reveal that HF can be successfully adapted to different contexts and for different populations without losing its fidelity. People receiving HF achieved superior housing outcomes and showed more rapid improvements in community functioning and quality of life than those receiving treatment as usual. Conclusions: Knowledge translation efforts have been undertaken to disseminate the positive findings and lessons learned from the AH–CS project and to scale up the HF approach across Canada. PMID:26720504

  15. Barriers and opportunities for enhancing patient recruitment and retention in clinical research: findings from an interview study in an NHS academic health science centre.

    Science.gov (United States)

    Adams, Mary; Caffrey, Louise; McKevitt, Christopher

    2015-03-12

    In the UK, the recruitment of patients into clinical research is a national health research and development policy priority. There has been limited investigation of how national level factors operate as barriers or facilitators to recruitment work, particularly from the perspective of staff undertaking patient recruitment work. The aim of this study is to identify and examine staff views of the key organisational barriers and facilitators to patient recruitment work in one clinical research group located in an NHS Academic Health Science Centre. A qualitative study utilizing in-depth, one-to-one semi-structured interviews with 11 purposively selected staff with particular responsibilities to recruit and retain patients as clinical research subjects. Thematic analysis classified interview data by recurring themes, concepts, and emergent categories for the purposes of establishing explanatory accounts. The findings highlight four key factors that staff perceived to be most significant for the successful recruitment and retention of patients in research and identify how staff located these factors within patients, studies, the research centre, the trust, and beyond the trust. Firstly, competition for research participants at an organisational and national level was perceived to undermine recruitment success. Secondly, the tension between clinical and clinical research workloads was seen to interrupt patient recruitment into studies, despite national funding arrangements to manage excess treatment costs. Thirdly, staff perceived an imbalance between personal patient burden and benefit. Ethical committee regulation, designed to protect patients, was perceived by some staff to detract from clarification and systematisation of incentivisation strategies. Finally, the structure and relationships within clinical research teams, in particular the low tacit status of recruitment skills, was seen as influential. The results of this case-study, conducted in an exemplary NHS

  16. Using the Consolidated Framework for Implementation Research (CFIR) to produce actionable findings: a rapid-cycle evaluation approach to improving implementation.

    Science.gov (United States)

    Keith, Rosalind E; Crosson, Jesse C; O'Malley, Ann S; Cromp, DeAnn; Taylor, Erin Fries

    2017-02-10

    Much research does not address the practical needs of stakeholders responsible for introducing health care delivery interventions into organizations working to achieve better outcomes. In this article, we present an approach to using the Consolidated Framework for Implementation Research (CFIR) to guide systematic research that supports rapid-cycle evaluation of the implementation of health care delivery interventions and produces actionable evaluation findings intended to improve implementation in a timely manner. To present our approach, we describe a formative cross-case qualitative investigation of 21 primary care practices participating in the Comprehensive Primary Care (CPC) initiative, a multi-payer supported primary care practice transformation intervention led by the Centers for Medicare and Medicaid Services. Qualitative data include observational field notes and semi-structured interviews with primary care practice leadership, clinicians, and administrative and medical support staff. We use intervention-specific codes, and CFIR constructs to reduce and organize the data to support cross-case analysis of patterns of barriers and facilitators relating to different CPC components. Using the CFIR to guide data collection, coding, analysis, and reporting of findings supported a systematic, comprehensive, and timely understanding of barriers and facilitators to practice transformation. Our approach to using the CFIR produced actionable findings for improving implementation effectiveness during this initiative and for identifying improvements to implementation strategies for future practice transformation efforts. The CFIR is a useful tool for guiding rapid-cycle evaluation of the implementation of practice transformation initiatives. Using the approach described here, we systematically identified where adjustments and refinements to the intervention could be made in the second year of the 4-year intervention. We think the approach we describe has broad

  17. Multispectral Image Feature Points

    Directory of Open Access Journals (Sweden)

    Cristhian Aguilera

    2012-09-01

    Full Text Available This paper presents a novel feature point descriptor for the multispectral image case: Far-Infrared and Visible Spectrum images. It allows matching interest points on images of the same scene but acquired in different spectral bands. Initially, points of interest are detected on both images through a SIFT-like based scale space representation. Then, these points are characterized using an Edge Oriented Histogram (EOH descriptor. Finally, points of interest from multispectral images are matched by finding nearest couples using the information from the descriptor. The provided experimental results and comparisons with similar methods show both the validity of the proposed approach as well as the improvements it offers with respect to the current state-of-the-art.

  18. Making SharePoint® Chemically Aware™.

    Science.gov (United States)

    Tallapragada, Kartik; Chewning, Joseph; Kombo, David; Ludwick, Beverly

    2012-01-12

    The use of SharePoint® collaboration software for content management has become a critical part of today's drug discovery process. SharePoint 2010 software has laid a foundation which enables researchers to collaborate and search on various contents. The amount of data generated during a transition of a single compound from preclinical discovery to commercialization can easily range in terabytes, thus there is a greater demand of a chemically aware search algorithm that supplements SharePoint which enables researchers to query for information in a more intuitive and effective way. Thus by supplementing SharePoint with Chemically Aware™ features provides a great value to the pharmaceutical and biotech companies and makes drug discovery more efficient. Using several tools we have integrated SharePoint with chemical, compound, and reaction databases, thereby improving the traditional search engine capability and enhancing the user experience. This paper describes the implementation of a Chemically Aware™ system to supplement SharePoint. A Chemically Aware SharePoint (CASP) allows users to tag documents by drawing a structure and associating it with the related content. It also allows the user to search SharePoint software content and internal/external databases by carrying out substructure, similarity, SMILES, and IUPAC name searches. Building on traditional search, CASP takes SharePoint one step further by providing a intuitive GUI to the researchers to base their search on their knowledge of chemistry than textual search. CASP also provides a way to integrate with other systems, for example a researcher can perform a sub-structure search on pdf documents with embedded molecular entities. A Chemically Aware™ system supplementing SharePoint is a step towards making drug discovery process more efficient and also helps researchers to search for information in a more intuitive way. It also helps the researchers to find information which was once difficult to find

  19. Making SharePoint® Chemically Aware™

    Directory of Open Access Journals (Sweden)

    Tallapragada Kartik

    2012-01-01

    Full Text Available Abstract Background The use of SharePoint® collaboration software for content management has become a critical part of today's drug discovery process. SharePoint 2010 software has laid a foundation which enables researchers to collaborate and search on various contents. The amount of data generated during a transition of a single compound from preclinical discovery to commercialization can easily range in terabytes, thus there is a greater demand of a chemically aware search algorithm that supplements SharePoint which enables researchers to query for information in a more intuitive and effective way. Thus by supplementing SharePoint with Chemically Aware™ features provides a great value to the pharmaceutical and biotech companies and makes drug discovery more efficient. Using several tools we have integrated SharePoint with chemical, compound, and reaction databases, thereby improving the traditional search engine capability and enhancing the user experience. Results This paper describes the implementation of a Chemically Aware™ system to supplement SharePoint. A Chemically Aware SharePoint (CASP allows users to tag documents by drawing a structure and associating it with the related content. It also allows the user to search SharePoint software content and internal/external databases by carrying out substructure, similarity, SMILES, and IUPAC name searches. Building on traditional search, CASP takes SharePoint one step further by providing a intuitive GUI to the researchers to base their search on their knowledge of chemistry than textual search. CASP also provides a way to integrate with other systems, for example a researcher can perform a sub-structure search on pdf documents with embedded molecular entities. Conclusion A Chemically Aware™ system supplementing SharePoint is a step towards making drug discovery process more efficient and also helps researchers to search for information in a more intuitive way. It also helps the

  20. 30 March 2009 - Representatives of the Danish Council for Independent Research Natural Sciences visiting the LHC tunnel at Point 1 with Collaboration Spokesperson F. Gianotti, Former Spokesperson P. Jenni and Transition Radiation Tracker Project Leader C. Rembser.

    CERN Document Server

    Maximilien Brice

    2009-01-01

    30 March 2009 - Representatives of the Danish Council for Independent Research Natural Sciences visiting the LHC tunnel at Point 1 with Collaboration Spokesperson F. Gianotti, Former Spokesperson P. Jenni and Transition Radiation Tracker Project Leader C. Rembser.

  1. Evidence-informed health policy 1 - synthesis of findings from a multi-method study of organizations that support the use of research evidence.

    Science.gov (United States)

    Lavis, John N; Oxman, Andrew D; Moynihan, Ray; Paulsen, Elizabeth J

    2008-12-17

    Organizations have been established in many countries and internationally to support the use of research evidence by producing clinical practice guidelines, undertaking health technology assessments, and/or directly supporting the use of research evidence in developing health policy on an international, national, and state or provincial level. Learning from these organizations can reduce the need to 'reinvent the wheel' and inform decisions about how best to organize support for such organizations, particularly in low- and middle-income countries (LMICs). We undertook a multi-method study in three phases - a survey, interviews, and case descriptions that drew on site visits - and in each of the second and third phases we focused on a purposive sample of those involved in the previous phase. We used the seven main recommendations that emerged from the advice offered in the interviews to organize much of the synthesis of findings across phases and methods. We used a constant comparative method to identify themes from across phases and methods. Seven recommendations emerged for those involved in establishing or leading organizations that support the use of research evidence in developing health policy: 1) collaborate with other organizations; 2) establish strong links with policymakers and involve stakeholders in the work; 3) be independent and manage conflicts of interest among those involved in the work; 4) build capacity among those working in the organization; 5) use good methods and be transparent in the work; 6) start small, have a clear audience and scope, and address important questions; and 7) be attentive to implementation considerations, even if implementation is not a remit. Four recommendations emerged for the World Health Organization (WHO) and other international organizations and networks: 1) support collaborations among organizations; 2) support local adaptation efforts; 3) mobilize support; and 4) create global public goods. This synthesis of

  2. Evidence-informed health policy 1 – Synthesis of findings from a multi-method study of organizations that support the use of research evidence

    Directory of Open Access Journals (Sweden)

    Moynihan Ray

    2008-12-01

    Full Text Available Abstract Background Organizations have been established in many countries and internationally to support the use of research evidence by producing clinical practice guidelines, undertaking health technology assessments, and/or directly supporting the use of research evidence in developing health policy on an international, national, and state or provincial level. Learning from these organizations can reduce the need to 'reinvent the wheel' and inform decisions about how best to organize support for such organizations, particularly in low- and middle-income countries (LMICs. Methods We undertook a multi-method study in three phases – a survey, interviews, and case descriptions that drew on site visits – and in each of the second and third phases we focused on a purposive sample of those involved in the previous phase. We used the seven main recommendations that emerged from the advice offered in the interviews to organize much of the synthesis of findings across phases and methods. We used a constant comparative method to identify themes from across phases and methods. Results Seven recommendations emerged for those involved in establishing or leading organizations that support the use of research evidence in developing health policy: 1 collaborate with other organizations; 2 establish strong links with policymakers and involve stakeholders in the work; 3 be independent and manage conflicts of interest among those involved in the work; 4 build capacity among those working in the organization; 5 use good methods and be transparent in the work; 6 start small, have a clear audience and scope, and address important questions; and 7 be attentive to implementation considerations, even if implementation is not a remit. Four recommendations emerged for the World Health Organization (WHO and other international organizations and networks: 1 support collaborations among organizations; 2 support local adaptation efforts; 3 mobilize support; and 4 create

  3. Point, Counterpoint.

    Science.gov (United States)

    Reich, Robert B.; Goleman, Daniel

    1999-01-01

    Robert B. Reich, former U.S. Secretary of Labor, and Daniel Goleman, researcher and author, debate the pros and cons of trends revealed by American Society for Training and Development's 1999 State of the Industry Report. (Author/JOW)

  4. [Modeling the requirements on routine data of general practitioners from the health-care researcher's point of view with the help of unified modeling langauge (UML)].

    Science.gov (United States)

    Kersting, M; Hauswaldt, J; Lingner, H

    2012-08-01

    Health-care research is, besides primary acquired study data, based on data from widely differing secondary sources. In order to link, compare and analyze data sources uniform models and methods are needed. This could be facilitated by a more structured description of requirements, models and methods of health-care research than those currently used. Suitable methods of presentation were sought in an approach to this target and the unified modeling language (UML) identified as a possible alternative. Using different tools 3 UML diagrams were created to represent some individual aspects of a scientific use file (SUF): A use case diagram as well as an activity and a class diagram. In the use case diagram we attempted to represent the general use cases of an SUF based on general practitioners routine data. Secondly a class diagram was constructed to visualize the contents and structure of a SUF. Thirdly an activity diagram was developed to graphically represent the concept of a general practitioner's episode of care. The creation of the UML diagrams was possible without any technical difficulties. Regarding the content the 3 diagrams must still be considered as prototypes. The use case diagram shows possible uses and users of an SUF, e. g. a research worker, industry but also the general practitioner who supplies the data. The class diagram reveals a general data structure that can serve information processes in practice and research. Besides aggregation, possibilities for specialization and generalization are essential elements of the class diagram that can be used meaningfully. The activity diagram for the schematic representation of a general practitioner's episode of care reveals the existence of multiple endpoints of an episode and the possibility to form relationships by means of episodes (diagnosis>therapy). The constructed diagrams are preliminary results and should be refined in future steps. Use case diagrams enable a rapid overview of the meaning and

  5. Cocaine treatment admissions at three sentinel sites in South Africa (1997–2006: findings and implications for policy, practice and research

    Directory of Open Access Journals (Sweden)

    Plüddemann Andreas

    2007-12-01

    Full Text Available Abstract Background Accurate prevalence data on cocaine use, that points to where problems exist and the extent of these problems, is necessary to guide the formulation of effective substance abuse policy and practice. The purpose of this study was to provide surveillance information about the nature and extent of problematic cocaine use in South Africa. Methods Data were collected between January 1997 and December 2006 on admissions for drug abuse treatment through a regular monitoring system involving 56 drug treatment centres and programmes in Cape Town, Gauteng Province (Johannesburg and Pretoria and the Eastern Cape every six months as part of the South African Community Epidemiology Network on Drug Use (SACENDU. A one-page form was completed by treatment centre personnel to obtain demographic data, the patients' primary and secondary substances of abuse, the mode, frequency and age of first use of substance, and information on prior treatment. Results Treatment indicators point to a significant increase in cocaine related admissions over time in all sites, but with substantial inter-site variation, particularly in recent years. The data indicate high levels of crack cocaine use and high levels of daily usage among patients, most of whom were first time admissions. Patients with cocaine related problems continue to be predominantly male, with a mean age of around 30 years. Substantial changes in the racial profile of patients have occurred over time. Poly drug use is high with cocaine often used with alcohol, cannabis and other drugs. Conclusion These trends point to the possibility of cocaine use becoming a serious health and social issue in South Africa and demonstrate the utility of continued monitoring of cocaine treatment admissions in the future. They also highlight the need to address cocaine use in national and provincial policy planning and intervention efforts. In terms of treatment, the findings highlight the need to ensure that

  6. Systematic review finds that study data not published in full text articles have unclear impact on meta-analyses results in medical research.

    Science.gov (United States)

    Schmucker, Christine M; Blümle, Anette; Schell, Lisa K; Schwarzer, Guido; Oeller, Patrick; Cabrera, Laura; von Elm, Erik; Briel, Matthias; Meerpohl, Joerg J

    2017-01-01

    A meta-analysis as part of a systematic review aims to provide a thorough, comprehensive and unbiased statistical summary of data from the literature. However, relevant study results could be missing from a meta-analysis because of selective publication and inadequate dissemination. If missing outcome data differ systematically from published ones, a meta-analysis will be biased with an inaccurate assessment of the intervention effect. As part of the EU-funded OPEN project (www.open-project.eu) we conducted a systematic review that assessed whether the inclusion of data that were not published at all and/or published only in the grey literature influences pooled effect estimates in meta-analyses and leads to different interpretation. Systematic review of published literature (methodological research projects). Four bibliographic databases were searched up to February 2016 without restriction of publication year or language. Methodological research projects were considered eligible for inclusion if they reviewed a cohort of meta-analyses which (i) compared pooled effect estimates of meta-analyses of health care interventions according to publication status of data or (ii) examined whether the inclusion of unpublished or grey literature data impacts the result of a meta-analysis. Seven methodological research projects including 187 meta-analyses comparing pooled treatment effect estimates according to different publication status were identified. Two research projects showed that published data showed larger pooled treatment effects in favour of the intervention than unpublished or grey literature data (Ratio of ORs 1.15, 95% CI 1.04-1.28 and 1.34, 95% CI 1.09-1.66). In the remaining research projects pooled effect estimates and/or overall findings were not significantly changed by the inclusion of unpublished and/or grey literature data. The precision of the pooled estimate was increased with narrower 95% confidence interval. Although we may anticipate that

  7. Finding potentially new multimorbidity patterns of psychiatric and somatic diseases: exploring the use of literature-based discovery in primary care research.

    Science.gov (United States)

    Vos, Rein; Aarts, Sil; van Mulligen, Erik; Metsemakers, Job; van Boxtel, Martin P; Verhey, Frans; van den Akker, Marjan

    2014-01-01

    Multimorbidity, the co-occurrence of two or more chronic medical conditions within a single individual, is increasingly becoming part of daily care of general medical practice. Literature-based discovery may help to investigate the patterns of multimorbidity and to integrate medical knowledge for improving healthcare delivery for individuals with co-occurring chronic conditions. To explore the usefulness of literature-based discovery in primary care research through the key-case of finding associations between psychiatric and somatic diseases relevant to general practice in a large biomedical literature database (Medline). By using literature based discovery for matching disease profiles as vectors in a high-dimensional associative concept space, co-occurrences of a broad spectrum of chronic medical conditions were matched for their potential in biomedicine. An experimental setting was chosen in parallel with expert evaluations and expert meetings to assess performance and to generate targets for integrating literature-based discovery in multidisciplinary medical research of psychiatric and somatic disease associations. Through stepwise reductions a reference set of 21,945 disease combinations was generated, from which a set of 166 combinations between psychiatric and somatic diseases was selected and assessed by text mining and expert evaluation. Literature-based discovery tools generate specific patterns of associations between psychiatric and somatic diseases: one subset was appraised as promising for further research; the other subset surprised the experts, leading to intricate discussions and further eliciting of frameworks of biomedical knowledge. These frameworks enable us to specify targets for further developing and integrating literature-based discovery in multidisciplinary research of general practice, psychology and psychiatry, and epidemiology.

  8. Power, paradigms and dominance in marketing research in Brazil: an analysis of the national production of the discipline from the point of view of epistemic matrices

    Directory of Open Access Journals (Sweden)

    Fernanda Bueno Cardoso Scussel

    2017-09-01

    Full Text Available Literature has indicated the insufficiency of the paradigmatic logic to study the social phenomena encompassed by marketing, also revealing the need for a maturation of the discipline’s epistemology. Considering this, we used epistemic matrices, an alternative approach to knowledge production in organizational studies, whose application to marketing is presented and discussed in this paper. Thus, this article articulates a debate on power, paradigms and dominance issues in marketing research in Brazil, presenting the results of an epistemological analysis that included 311 papers from the Anpad Marketing Congress (Encontro de Marketing da Anpad – EMA in the last five years. The information extracted from the articles were framework of the study and epistemological orientation. This analysis allowed us to identify the most frequent topics that were conceptually debated, the dominant logics of the empirical studies and the perspectives for the development of future investigations. Among the main findings are the need fortheoretical construction within the discipline, the emergence of interpretative and critical studies, and the strengthening of multi-method studies, that bring hopes of overcoming the duality between positive and interpretive logic, thus leading marketing to the study of phenomena as a whole.

  9. The impact of a tobacco point-of-sale display ban on youth in the United Kingdom: findings from a repeat cross-sectional survey pre-, mid- and post-implementation

    Directory of Open Access Journals (Sweden)

    Allison Ford

    2018-03-01

    Full Text Available Background The display of tobacco products at the point-of-sale (POS allows tobacco companies to showcase their products and communicate with consumers. Evidence suggests that exposure to POS tobacco displays is associated with impulse tobacco purchasing among adult smokers and smoking susceptibility among never smoking youth. In the United Kingdom (UK a ban on the open display of tobacco products was phased in between 2012 and 2015. Three waves of the Youth Tobacco Policy Survey were used to examine the impact of the ban on youth pre-, mid- and post-implementation. Methods A repeat cross-sectional survey was conducted with 11-16 year olds across the UK. Data was collected via an in-home face-to-face interview and self-completion questionnaire at three time points: pre- (2011, n=1373, mid- (2014, n=1205, and post-display ban (2016, n=1213. We examined whether the salience of displays was associated with smoking susceptibility among never smokers. Measures also explored cigarette brand awareness, attractiveness of displays and support for a display ban. Results In 2011, pre-ban, susceptibility to smoke was positively associated with noticing cigarettes displayed at POS and higher brand awareness. Susceptibility to smoke decreased from 28% in 2011 (pre-ban to 18% in 2016 (post-ban, with the mean number of brands recalled falling from 1.56 (SD=1.88 in 2011 to 1.01 (SD=1.42 in 2016. With respect to support for the ban, in 2016 the vast majority of our sample (87% indicated that shops should have to keep cigarettes behind closed shutters. They also felt that having them behind closed shutters made them seem unappealing (73% and made them think that it's not ok to smoke (83%. Conclusions That smoking susceptibility was lower following the ban suggests that placing tobacco out of sight helps safeguard young people and justifies this policy approach in the UK and elsewhere.

  10. The Influence of Setting on Findings Produced in Qualitative Health Research: A Comparison between Face-to-Face and Online Discussion Groups about HIV/AIDS

    Directory of Open Access Journals (Sweden)

    Guendalina Graffigna

    2006-09-01

    Full Text Available The authors focus their analysis in this article on online focus groups (FGs, in an attempt to describe how the setting shapes the conversational features of the discussion and influences data construction. Starting from a review of current dominant viewpoints, they compare face-to-face discussion groups with different formats of online FGs about AIDS, from a discourse analysis perspective. They conducted 2 face-to-face FGs, 2 chats, 2 forums, and 2 forums+plus+chat involving 64 participants aged 18 to 25 and living in Italy. Their findings seem not only to confirm the hypothesis of a general difference between a face-to-face discussion setting and an Internet-mediated one but also reveal differences among the forms of online FG, in terms of both the thematic articulation of discourse and the conversational and relational characteristics of group exchange, suggesting that exchanges on HIV/AIDS are characterized by the setting. This characterization seems to be important for situating the choice of tool, according to research objectives, and for better defining the technical aspects of the research project.

  11. Reliability of routine clinical measurements of neonatal circumferences and research measurements of neonatal skinfold thicknesses: findings from the Born in Bradford study

    Science.gov (United States)

    West, Jane; Manchester, Ben; Wright, John; Lawlor, Debbie A; Waiblinger, Dagmar

    2011-01-01

    Summary West J, Manchester B, Wright J, Lawlor DA, Waiblinger D. Reliability of routine clinical measurements of neonatal circumferences and research measurements of neonatal skinfold thicknesses: findings from the Born in Bradford study. Paediatric and Perinatal Epidemiology 2011. Assessing neonatal size reliably is important for research and clinical practice. The aim of this study was to examine the reliability of routine clinical measurements of neonatal circumferences and of skinfold thicknesses assessed for research purposes. All measurements were undertaken on the same population of neonates born in a large maternity unit in Bradford, UK. Technical error of measurement (TEM), relative TEM and the coefficient of reliability are reported. Intra-observer TEMs for routine circumference measurements were all below 0.4 cm and were generally within ±2-times the mean. Inter-observer TEM ranged from 0.20 to 0.36 cm for head circumference, 0.19 to 0.39 cm for mid upper arm circumference and from 0.39 to 0.77 cm for abdominal circumference. Intra and inter-observer TEM for triceps skinfold thickness ranged from 0.22 to 0.35 mm and 0.15 to 0.54 mm, respectively. Subscapular skinfold thickness TEM values were 0.14 to 0.25 mm for intra-observer measurements and 0.17 to 0.63 mm for inter-observer measurements. Relative TEM values for routine circumferences were all below 4.00% but varied between 2.88% and 14.23% for research skinfold measurements. Reliability was mostly between 80% and 99% for routine circumference measurements and ≥70% for most research skinfold measurements. Routine clinical measurements of neonatal circumferences are reliably assessed in Bradford. Assessing skinfolds in neonates has variable reliability, but on the whole is good. The greater intra-observer, compared with inter-observer, reliability for both sets of measurements highlights the importance of having a minimal number of assessors whenever possible. PMID:21281329

  12. The Research Seminar “New Sources on the Medieval Turkic-Tatar History: New Findings, Interpretation, Prospects for Research” (Kazan, December 6, 2017

    Directory of Open Access Journals (Sweden)

    L.S. Giniyatullina

    2018-03-01

    Full Text Available The research seminar “New Sources on the Medieval Turkic-Tatar History: New Findings, Interpretation, Prospects for Research” was held at the Sh. Marjani Institute of History of Tatarstan Academy of Sciences on December 6, 2017 in the framework of the International Scientific and Practical Conference, “The Epoch through the Person’s Prism: 130th Anniversary of Gaziz Gubaidullin”. The head of the M.A. Usmanov Center for Research of the Golden Horde and the Tatar Khanate (Sh. Marjani Institute of History of the Tatarstan Academy of Sciences, I.M. Mirgaleev, acted as the coordinator of the seminar and spoke about the importance of studying new sources on medieval Turkic-Tatar history and introducing them into current scholarly discussions. Scholars from academic centers of Russia, Great Britain, and Finland took part in the seminar. Doctor of Historical Studies, Ilya Vladimirovich Zaitsev, acted as its main spea­ker. His speech was devoted to the recently discovery of the “History of Chinggis Khan” by Mansur ibn Abdarrakhman (1741. I.V. Zaitsev described the biography of the author, the history of the creation, and the present study of this work. The next meeting of the editorial board of the research journal, “Golden Horde Review”, was held on the same day, where the following issues related to the development of the journal’s activities were discussed: – the work of the editorial board; – peer review problems; – increasing the proportion of English articles; – unification of bibliographic format. The editor-in-chief, I.M. Mirgaleev, briefly acquainted colleagues with activities of the journal’s editorial board and discussed the successful inclusion of the journal in the citation databases Scopus and WoS, as well as in the list of the Higher Attestation Commission.

  13. Advanced Visualization and Interactive Display Rapid Innovation and Discovery Evaluation Research (VISRIDER) Program Task 6: Point Cloud Visualization Techniques for Desktop and Web Platforms

    Science.gov (United States)

    2017-04-01

    backend point cloud server ................... 34 List of Tables Table 1 - Measured frame rate from point cloud benchmark...variant, OpenGL ES, that is is used by all modern phones and tablets to provide hardware acceleration in the mobile space. WebGL is a JavaScript language...WebGL. These mainly reside in complex buffer operations that aren’t exposed in the mobile version OpenGL ES. The biggest omission from WebGL though

  14. Finding Sliesthorp?

    DEFF Research Database (Denmark)

    Dobat, Andres S.

    2016-01-01

    In 2003, a hitherto unknown Viking age settlement was discovered at Füsing in Northern Germany close to Hedeby/Schleswig, the largest of the early Scandinavian towns. Finds and building features suggest a high status residence and a seat of some chiefly elite that flourished from around 700 to th...... and the transformation of socio‐political structures in Northern Europe as it transitioned from prehistory into the middle Ages....

  15. Anticipate and communicate: Ethical management of incidental and secondary findings in the clinical, research, and direct-to-consumer contexts (December 2013 report of the Presidential Commission for the Study of Bioethical Issues).

    Science.gov (United States)

    Weiner, Christine

    2014-09-15

    Genomic population research increases the possibility of finding genetic coding anomalies that are not the primary object of research but may have significance for the current and future medical care of research participants and progeny. The December 2013 Report of the Presidential Commission for the Study of Bioethical Issues (Anticipate and Communicate: Ethical Management of Incidental and Secondary Findings in the Clinical, Research, and Direct-to-Consumer Contexts (http://bioethics.gov/sites/default/files/FINALAnticipateCommunicate_PCSBI_0.pdf)) recommends that a researcher anticipate these findings and make a plan that addresses which findings will be communicated to research participants and how. Following these recommendations will be disruptive for both investigators and institutional review boards (IRBs) until the research community reaches consensus, or a mechanism for evolving consensus, on which results should be returned to research participants. A protocol-by-protocol approach, though laborious, makes sense for both investigators and IRBs as the research community thinks through the implications of genomic research. Epidemiologists will note that discussion of the return of results and the plan for communicating findings should be included in both the participant consent agreement and the research protocol submitted to the IRB. © The Author 2014. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  16. Research Update: Point defects in CdTexSe1−x crystals grown from a Te-rich solution for applications in detecting radiation

    International Nuclear Information System (INIS)

    Gul, R.; Roy, U. N.; Bolotnikov, A. E.; Camarda, G. S.; Cui, Y.; Hossain, A.; Yang, G.; James, R. B.; Lee, W.; Cui, Y.; Burger, A.

    2015-01-01

    We investigated cadmium telluride selenide (CdTeSe) crystals, newly grown by the Traveling Heater Method (THM), for the presence and abundance of point defects. Current Deep Level Transient spectroscopy (I-DLTS) was used to determine the energies of the traps, their capture cross sections, and densities. The bias across the detectors was varied from 1 to 30 V. Four types of point defects were identified, ranging from 10 meV to 0.35 eV. Two dominant traps at energies of 0.18 eV and 0.14 eV were studied in depth. Cd vacancies are found at lower concentrations than other point defects present in the material

  17. The Human Mind As General Problem Solver, Is Observed To Find ``Best'' Solutions, That Correspond To Highest Mental Coherence: Will Discuss ``sing Glass Type Theory'' of Princeton Physicist J J Hopfield, Points To How Best Use Our Own Human Mind!!

    Science.gov (United States)

    Gurr, Henry

    2014-03-01

    Princeton Physicist J. J. Hopfield's Mathematical Model of the Mammalian Brain, (Similar To Ising Glass Model of a crystal of magnetic spin particles) says our Brain-Work for Memory, Perception, Language, Thinking, etc, (Even the AHA-EUREKA-Flash Of Insight Type Problem Solving), is achieved by our massively inter-connected CNS Neurons ... working together ... MINIMIZING an analog of physical energy ... thus yielding Optimal Solutions: These ``best'' answers, correspond to highest mental coherence, for most facets organism response, beit mental (eg: perception, memory, ideas, thinking, etc) or physical-muscular-actions (eg speaking, tool using, trail following, etc). Our brain is this way, because living creature, MUST be evolved, so they will find & use the best actions, for survival!!! Our human heritage, is to instantly compute near optimal future plans, (mental & physical-muscular), and be able to accomplish plans reliably & efficiently. If you know of book or articles in these topic areas, please email to HenryG--USCA.edu How to work well, with your own ``self'', called mind-body, will follow!! Conjectures: Who is the ``I'' that appears to make decisions? Am ``I'' the master of my domain? Is there an ``I'' or am ``I'' merely an illusion of reality.

  18. Examining Neighborhood Social Cohesion in the Context of Community-based Participatory Research: Descriptive Findings from an Academic-Community Partnership.

    Science.gov (United States)

    Bateman, Lori Brand; Fouad, Mona N; Hawk, Bianca; Osborne, Tiffany; Bae, Sejong; Eady, Sequoya; Thompson, Joanice; Brantley, Wendy; Crawford, Lovie; Heider, Laura; Schoenberger, Yu-Mei M

    2017-01-01

    The purpose of this article is to describe the process of conducting an assessment of neighborhood perceptions and cohesion by a community coalition-academic team created in the context of community-based participatory research (CBPR), to guide the design of locally relevant health initiatives. Guided by CBPR principles, a collaborative partnership was established between an academic center and a local, urban, underserved neighborhood in Birmingham, Alabama to identify and address community concerns and priorities. A cross-sectional survey was conducted in September 2016 among community residents (N=90) to examine perceptions of neighborhood characteristics, including social cohesion and neighborhood problems. The major concerns voiced by the coalition were violence and lack of neighborhood cohesion and safety. The community survey verified the concerns of the coalition, with the majority of participants mentioning increasing safety and stopping the violence as the things to change about the community and the greatest hope for the community. Furthermore, results indicated residents had a moderate level of perceived social cohesion (mean = 2.87 [.67]). The Mid-South TCC Academic and Community Engagement (ACE) Core successfully partnered with community members and stakeholders to establish a coalition whose concerns and vision for the community matched the concerns of residents of the community. Collecting data from different groups strengthened the interpretation of the findings and allowed for a rich understanding of neighborhood concerns.

  19. Ernst Rüdin's Unpublished 1922-1925 Study "Inheritance of Manic-Depressive Insanity": Genetic Research Findings Subordinated to Eugenic Ideology.

    Science.gov (United States)

    Kösters, Gundula; Steinberg, Holger; Kirkby, Kenneth Clifford; Himmerich, Hubertus

    2015-11-01

    In the early 20th century, there were few therapeutic options for mental illness and asylum numbers were rising. This pessimistic outlook favoured the rise of the eugenics movement. Heredity was assumed to be the principal cause of mental illness. Politicians, scientists and clinicians in North America and Europe called for compulsory sterilisation of the mentally ill. Psychiatric genetic research aimed to prove a Mendelian mode of inheritance as a scientific justification for these measures. Ernst Rüdin's seminal 1916 epidemiological study on inheritance of dementia praecox featured large, systematically ascertained samples and statistical analyses. Rüdin's 1922-1925 study on the inheritance of "manic-depressive insanity" was completed in manuscript form, but never published. It failed to prove a pattern of Mendelian inheritance, counter to the tenets of eugenics of which Rüdin was a prominent proponent. It appears he withheld the study from publication, unable to reconcile this contradiction, thus subordinating his carefully derived scientific findings to his ideological preoccupations. Instead, Rüdin continued to promote prevention of assumed hereditary mental illnesses by prohibition of marriage or sterilisation and was influential in the introduction by the National Socialist regime of the 1933 "Law for the Prevention of Hereditarily Diseased Offspring" (Gesetz zur Verhütung erbkranken Nachwuchses).

  20. Ernst Rüdin’s Unpublished 1922-1925 Study “Inheritance of Manic-Depressive Insanity”: Genetic Research Findings Subordinated to Eugenic Ideology

    Science.gov (United States)

    Kösters, Gundula; Steinberg, Holger; Kirkby, Kenneth Clifford; Himmerich, Hubertus

    2015-01-01

    In the early 20th century, there were few therapeutic options for mental illness and asylum numbers were rising. This pessimistic outlook favoured the rise of the eugenics movement. Heredity was assumed to be the principal cause of mental illness. Politicians, scientists and clinicians in North America and Europe called for compulsory sterilisation of the mentally ill. Psychiatric genetic research aimed to prove a Mendelian mode of inheritance as a scientific justification for these measures. Ernst Rüdin’s seminal 1916 epidemiological study on inheritance of dementia praecox featured large, systematically ascertained samples and statistical analyses. Rüdin’s 1922–1925 study on the inheritance of “manic-depressive insanity” was completed in manuscript form, but never published. It failed to prove a pattern of Mendelian inheritance, counter to the tenets of eugenics of which Rüdin was a prominent proponent. It appears he withheld the study from publication, unable to reconcile this contradiction, thus subordinating his carefully derived scientific findings to his ideological preoccupations. Instead, Rüdin continued to promote prevention of assumed hereditary mental illnesses by prohibition of marriage or sterilisation and was influential in the introduction by the National Socialist regime of the 1933 “Law for the Prevention of Hereditarily Diseased Offspring” (Gesetz zur Verhütung erbkranken Nachwuchses). PMID:26544949

  1. The Philosophy of Turning Points

    DEFF Research Database (Denmark)

    Turcan, Romeo V.

    2013-01-01

    business and management field, the turning point is seen as a valuable unit of analysis within the research field. It is expected that this paper will encourage a dynamic scholarly conversation about the concept of turning point and how it can aid international business researchers in the development...

  2. Detecting Change-Point via Saddlepoint Approximations

    Institute of Scientific and Technical Information of China (English)

    Zhaoyuan LI; Maozai TIAN

    2017-01-01

    It's well-known that change-point problem is an important part of model statistical analysis.Most of the existing methods are not robust to criteria of the evaluation of change-point problem.In this article,we consider "mean-shift" problem in change-point studies.A quantile test of single quantile is proposed based on saddlepoint approximation method.In order to utilize the information at different quantile of the sequence,we further construct a "composite quantile test" to calculate the probability of every location of the sequence to be a change-point.The location of change-point can be pinpointed rather than estimated within a interval.The proposed tests make no assumptions about the functional forms of the sequence distribution and work sensitively on both large and small size samples,the case of change-point in the tails,and multiple change-points situation.The good performances of the tests are confirmed by simulations and real data analysis.The saddlepoint approximation based distribution of the test statistic that is developed in the paper is of independent interest and appealing.This finding may be of independent interest to the readers in this research area.

  3. Finding Bureaucracy

    OpenAIRE

    Rønningstad, Chris Andre

    2015-01-01

    This thesis will use survey data from Norwegian managers to answer the following research question: Are managers in public administrations more bureaucratic in their attitudes toward structure and values than managers in private enterprises? I will argue that the classical bureaucracy, as described by Max Weber, can be understood as defined by structure and values. One often disparages the structural elements of bureaucracy and forgets about the bureaucratic values. The mean scores from AFF's...

  4. Surgical Findings and Outcomes in Premenopausal Breast Cancer Patients Undergoing Oophorectomy: A Multicenter Review From the Society of Gynecologic Surgeons Fellows Pelvic Research Network.

    Science.gov (United States)

    Harvey, Lara F B; Abramson, Vandana G; Alvarez, Jimena; DeStephano, Christopher; Hur, Hye-Chun; Lee, Katherine; Mattingly, Patricia; Park, Beau; Piszczek, Carolyn; Seifi, Farinaz; Stuparich, Mallory; Yunker, Amanda

    2018-01-01

    To describe the procedures performed, intra-abdominal findings, and surgical pathology in a cohort of women with premenopausal breast cancer who underwent oopherectomy. Multicenter retrospective chart review (Canadian Task Force classification II-3). Nine US academic medical centers participating in the Fellows' Pelvic Research Network (FPRN). One hundred twenty-seven women with premenopausal breast cancer undergoing oophorectomy between January 2013 and March 2016. Surgical castration. The mean patient age was 45.8 years. Fourteen patients (11%) carried a BRCA mutations, and 22 (17%) carried another germline or acquired mutation, including multiple variants of uncertain significance. There was wide variation in surgical approach. Sixty-five patients (51%) underwent pelvic washings, and 43 (35%) underwent concurrent hysterectomy. Other concomitant procedures included midurethral sling placement, appendectomy, and hysteroscopy. Three patients experienced complications (transfusion, wound cellulitis, and vaginal cuff dehiscence). Thirteen patients (10%) had ovarian pathology detected on analysis of the surgical specimen, including metastatic tumor, serous cystadenomas, endometriomas, and Brenner tumor. Eight patients (6%) had Fallopian tube pathology, including 3 serous tubal intraepithelial cancers. Among the 44 uterine specimens, 1 endometrial adenocarcinoma and 1 multifocal endometrial intraepithelial neoplasia were noted. Regarding the entire study population, the number of patients meeting our study criteria and seen by gynecologic surgeons in the FPRN for oophorectomy increased by nearly 400% from 2013 to 2015. Since publication of the Suppression of Ovarian Function Trial data, bilateral oophorectomy has been recommended for some women with premenopausal breast cancer to facilitate breast cancer treatment with aromatase inhibitors. These women may be at elevated risk for occult abdominal pathology compared with the general population. Gynecologic surgeons

  5. Improving Aboriginal maternal and infant health services in the 'Top End' of Australia; synthesis of the findings of a health services research program aimed at engaging stakeholders, developing research capacity and embedding change.

    Science.gov (United States)

    Barclay, Lesley; Kruske, Sue; Bar-Zeev, Sarah; Steenkamp, Malinda; Josif, Cathryn; Narjic, Concepta Wulili; Wardaguga, Molly; Belton, Suzanne; Gao, Yu; Dunbar, Terry; Kildea, Sue

    2014-06-02

    Health services research is a well-articulated research methodology and can be a powerful vehicle to implement sustainable health service reform. This paper presents a summary of a five-year collaborative program between stakeholders and researchers that led to sustainable improvements in the maternity services for remote-dwelling Aboriginal women and their infants in the Top End (TE) of Australia. A mixed-methods health services research program of work was designed, using a participatory approach. The study area consisted of two large remote Aboriginal communities in the Top End of Australia and the hospital in the regional centre (RC) that provided birth and tertiary care for these communities. The stakeholders included consumers, midwives, doctors, nurses, Aboriginal Health Workers (AHW), managers, policy makers and support staff. Data were sourced from: hospital and health centre records; perinatal data sets and costing data sets; observations of maternal and infant health service delivery and parenting styles; formal and informal interviews with providers and women and focus groups. Studies examined: indicator sets that identify best care, the impact of quality of care and remoteness on health outcomes, discrepancies in the birth counts in a range of different data sets and ethnographic studies of 'out of hospital' or health centre birth and parenting. A new model of maternity care was introduced by the health service aiming to improve care following the findings of our research. Some of these improvements introduced during the five-year research program of research were evaluated. Cost effective improvements were made to the acceptability, quality and outcomes of maternity care. However, our synthesis identified system-wide problems that still account for poor quality of infant services, specifically, unacceptable standards of infant care and parent support, no apparent relationship between volume and acuity of presentations and staff numbers with the

  6. FIND Tuberculosis Strain Bank: a Resource for Researchers and Developers Working on Tests To Detect Mycobacterium tuberculosis and Related Drug Resistance.

    Science.gov (United States)

    Tessema, Belay; Nabeta, Pamela; Valli, Eloise; Albertini, Audrey; Collantes, Jimena; Lan, Nguyen Huu; Romancenco, Elena; Tukavdze, Nestani; Denkinger, Claudia M; Dolinger, David L

    2017-04-01

    The spread of multidrug-resistant (MDR) tuberculosis (TB) and extensively drug-resistant (XDR) TB hampers global efforts in the fight against tuberculosis. To enhance the development and evaluation of diagnostic tests quickly and efficiently, well-characterized strains and samples from drug-resistant tuberculosis patients are necessary. In this project, the Foundation for Innovative New Diagnostics (FIND) has focused on the collection, characterization, and storage of such well-characterized reference materials and making them available to researchers and developers. The collection is being conducted at multiple centers in Southeast Asia, South America, Eastern Europe, and soon the sub-Saharan Africa regions. Strains are characterized for their phenotypic resistances and MICs to first-line drugs (FLDs) and second-line drugs (SLDs) using the automated MGIT 960 system following validated procedures and WHO criteria. Analysis of resistance-associated mutations is done by whole-genome sequencing (WGS) using the Illumina NextSeq system. Mycobacterial interspersed repetitive-unit-variable-number tandem-repeat analysis and WGS are used to determine strain lineages. All strains are maintained frozen at -80°C ± 10°C as distinct mother and daughter lots. All strains are extensively quality assured. The data presented here represent an analysis of the initial part of the collection. Currently, the bank contains 118 unique strains with extracted genomic DNA and matched sputum, serum, and plasma samples and will be expanded to a minimum of 1,000 unique strains over the next 3 years. Analysis of the current strains by phenotypic resistance testing shows 102 (86.4%), 10 (8.5%), and 6 (5.1%) MDR, XDR, and mono/poly resistant strains, respectively. Two of the strains are resistant to all 11 drugs that were phenotypically tested. WGS mutation analysis revealed FLD resistance-associated mutations in the rpoB , katG , inhA , embB , embA , and pncA genes; SLD resistance in the gyr

  7. Rationale and design of the DP-TRANSFERS project: diabetes prevention-transferring findings from European research to society in Catalonia.

    Science.gov (United States)

    Costa, Bernardo; Castell, Conxa; Cos, Xavier; Solé, Claustre; Mestre, Santiago; Canela, Marta; Boquet, Antoni; Cabré, Joan-Josep; Barrio, Francisco; Flores-Mateo, Gemma; Ferrer-Vidal, Daniel; Lindström, Jaana

    2016-04-27

    Compelling evidence has been accumulated to support the effectiveness of intensive lifestyle intervention in delaying progression to Type 2 diabetes even in people identified as being at high risk determined by the Finnish diabetes risk score. The DE-PLAN-CAT project (diabetes in Europe-prevention using lifestyle, physical activity and nutritional intervention-Catalonia) evidenced that intensive lifestyle intervention was feasible and cost-effective on a short scale in real-life primary care settings, at least over 4 years. However, transferring such lifestyle interventions to society remains the major challenge of research in the field of diabetes prevention. The derived DP-TRANSFERS (diabetes prevention-transferring findings from European research to society) is a large scale national programme aimed at translating a tailored lifestyle intervention to the maximum of primary care centres where feasible through a core proposal agreed with all the partners. The method is built upon a 3-step (screening, intervention and follow-up) real-life, community-wide structure on the basis of a dual intensity lifestyle intervention (basic and continuity modules) and supported by a 4-channel transfer strategy (institutional relationships, facilitators' workshops, collaborative groupware and programme WEB page). Participation will initially cover nine health departments (7 million inhabitants) through nine coordinating centres located in metropolitan (3.2 million), semi-urban (2.9 million) and rural (0.9 million) areas from which it is expected accessing 25 % of all primary care settings, equivalent to 90 associated centres (1.6-1.8 million people) with an estimate of 0.32 million participants aged 45-75 years at high risk of future development of diabetes. To ascertain sustainability, effect, satisfaction and quality of the translation programme statistical analyses will be performed from both the entire population (facilitators and participants) and a stratified

  8. Identification of risk factors for new-onset sciatica in Japanese workers: findings from the Japan epidemiological research of Occupation-related Back pain study.

    Science.gov (United States)

    Matsudaira, Ko; Kawaguchi, Mika; Isomura, Tatsuya; Arisaka, Mayumi; Fujii, Tomoko; Takeshita, Katsushi; Kitagawa, Tomoaki; Miyoshi, Kota; Konishi, Hiroaki

    2013-12-15

    Two-year, prospective cohort data collected for the Japan epidemiological research of Occupation-related Back pain study were used for the analysis. To identify potential risk factors for the development of new-onset sciatica in initially symptom-free Japanese workers with no history of sciatica. Although the associations between individual and occupational factors and cases of new-onset sciatica are established, the effect of psychosocial factors on the development of sciatica has still not been adequately clarified. In total, 5310 participants responded to a self-administered baseline questionnaire (response rate: 86.5%). Furthermore, 3194 (60.2%) completed both 1- and 2-year follow-up questionnaires. The baseline questionnaire assessed individual characteristics, ergonomic work demands, and work-related psychosocial factors. The outcome of interest was new-onset sciatica with or without low back pain during the 2-year follow-up period. Incidence was calculated for participants who reported no low back pain in the preceding year and no history of lumbar radicular pain (sciatica) at baseline. Logistical regression assessed risk factors associated with new-onset sciatica. Of 765 eligible participants, 141 (18.4%) reported a new episode of sciatica during the 2-year follow-up. In crude analysis, significant associations were found between new-onset sciatica and age and obesity. In adjusted analysis, significant associations were found for obesity and mental workload in a qualitative aspect after controlling for age and sex. Consequently, in multivariate analysis with all the potential risk factors, age and obesity remained statistically significant (odds ratios: 1.59, 95% confidence interval: 1.01-2.52; odds ratios: 1.77, 95% confidence interval: 1.17-2.68, respectively). In previously asymptomatic Japanese workers, the risk of developing new-onset sciatica is mediated by individual factors. Our findings suggest that the management of obesity may prevent new

  9. Public stigma against family members of people with mental illness: findings from the Gilgel Gibe Field Research Center (GGFRC), Southwest Ethiopia

    Science.gov (United States)

    2014-01-01

    Background Public stigma against family members of people with mental illness is a negative attitude by the public which blame family members for the mental illness of their relatives. Family stigma can result in self social restrictions, delay in treatment seeking and poor quality of life. This study aimed at investigating the degree and correlates of family stigma. Methods A quantitative cross-sectional house to house survey was conducted among 845 randomly selected urban and rural community members in the Gilgel Gibe Field Research Center, Southwest Ethiopia. An interviewer administered and pre-tested questionnaire adapted from other studies was used to measure the degree of family stigma and to determine its correlates. Data entry was done by using EPI-DATA and the analysis was performed using STATA software. Unadjusted and adjusted linear regression analysis was done to identify the correlates of family stigma. Results Among the total 845 respondents, 81.18% were female. On a range of 1 to 5 score, the mean family stigma score was 2.16 (±0.49). In a multivariate analysis, rural residents had significantly higher stigma scores (std. β = 0.43, P supernatural (std. β = -0.12, P supernatural explanation of mental illness was significantly correlated with lower stigma among individuals with lower level of exposure to people with mental illness (PWMI). On the other hand, high exposure to PWMI was significantly associated with lower stigma among respondents who had high education. Stigma scores increased with increasing income among respondents who had lower educational status. Conclusions Our findings revealed moderate level of family stigma. Place of residence, perceived signs and explanations of mental illness were independent correlates of public stigma against family members of people with mental illness. Therefore, mental health communication programs to inform explanations and signs of mental illness need to be implemented. PMID:24555444

  10. Public stigma against family members of people with mental illness: findings from the Gilgel Gibe Field Research Center (GGFRC), Southwest Ethiopia.

    Science.gov (United States)

    Girma, Eshetu; Möller-Leimkühler, Anne Maria; Müller, Norbert; Dehning, Sandra; Froeschl, Guenter; Tesfaye, Markos

    2014-02-21

    Public stigma against family members of people with mental illness is a negative attitude by the public which blame family members for the mental illness of their relatives. Family stigma can result in self social restrictions, delay in treatment seeking and poor quality of life. This study aimed at investigating the degree and correlates of family stigma. A quantitative cross-sectional house to house survey was conducted among 845 randomly selected urban and rural community members in the Gilgel Gibe Field Research Center, Southwest Ethiopia. An interviewer administered and pre-tested questionnaire adapted from other studies was used to measure the degree of family stigma and to determine its correlates. Data entry was done by using EPI-DATA and the analysis was performed using STATA software. Unadjusted and adjusted linear regression analysis was done to identify the correlates of family stigma. Among the total 845 respondents, 81.18% were female. On a range of 1 to 5 score, the mean family stigma score was 2.16 (± 0.49). In a multivariate analysis, rural residents had significantly higher stigma scores (std. β = 0.43, P mental illness increased, the stigma scores decreased significantly. High supernatural explanation of mental illness was significantly correlated with lower stigma among individuals with lower level of exposure to people with mental illness (PWMI). On the other hand, high exposure to PWMI was significantly associated with lower stigma among respondents who had high education. Stigma scores increased with increasing income among respondents who had lower educational status. Our findings revealed moderate level of family stigma. Place of residence, perceived signs and explanations of mental illness were independent correlates of public stigma against family members of people with mental illness. Therefore, mental health communication programs to inform explanations and signs of mental illness need to be implemented.

  11. The research of the coupled orbital-attitude controlled motion of celestial body in the neighborhood of the collinear libration point L1

    Science.gov (United States)

    Shmyrov, A.; Shmyrov, V.; Shymanchuk, D.

    2017-10-01

    This article considers the motion of a celestial body within the restricted three-body problem of the Sun-Earth system. The equations of controlled coupled attitude-orbit motion in the neighborhood of collinear libration point L1 are investigated. The translational orbital motion of a celestial body is described using Hill's equations of circular restricted three-body problem of the Sun-Earth system. Rotational orbital motion is described using Euler's dynamic equations and quaternion kinematic equation. We investigate the problem of stability of celestial body rotational orbital motion in relative equilibrium positions and stabilization of celestial body rotational orbital motion with proposed control laws in the neighborhood of collinear libration point L1. To study stabilization problem, Lyapunov function is constructed in the form of the sum of the kinetic energy and special "kinematic function" of the Rodriguez-Hamiltonian parameters. Numerical modeling of the controlled rotational motion of a celestial body at libration point L1 is carried out. The numerical characteristics of the control parameters and rotational motion are given.

  12. Research

    African Journals Online (AJOL)

    abp

    2016-04-26

    Apr 26, 2016 ... 2001 [11,12]: Risk factors weighting 5 points (stroke < 1 month), 3 points (age of 75 years or ... Thereafter, a general clinical exam was conducted, taking in symptoms and .... Cameroun (à propos de 18 cas). Med Trop (Mars).

  13. Main findings

    International Nuclear Information System (INIS)

    2014-01-01

    Licensing regimes vary from country to country. When the license regime involves several regulators and several licenses, this may lead to complex situations. Identifying a leading organisation in charge of overall coordination including preparation of the licensing decision is a useful practice. Also, if a stepwise licensing process is implemented, it is important to fix in legislation decisions and/or time points and to identify the relevant actors. There is considerable experience in civil and mining engineering that can be applied when constructing a deep geological disposal facility. Specific challenges are, however, the minimization of disturbances to the host rock and the understanding of its long-term behavior. Construction activities may affect the geo-hydraulic and geochemical properties of the various system components which are important safety features of the repository system. Clearly defined technical specifications and an effective quality management plan are important in ensuring successful repository implementation which is consistent with safety requirements. Monitoring plan should also be defined in advance. The regulatory organization should prepare itself to the licensing review before construction by allocating sufficient resources. It should increase its competence, e.g., by interacting early with the implementer and through its own R and D. This will allow the regulator to define appropriate technical conditions associated to the construction license and to elaborate a relevant inspection plan of the construction work. After construction, obtaining the operational license is the most important and crucial step. Main challenges include (a) establishing sufficient confidence so that the methods for closing the individual disposal units comply with the safety objectives and (b) addressing the issue of ageing of materials during a 50-100 years operational period. This latter challenge is amplified when reversibility/retrievability is required

  14. Electroencephalographic findings in panic disorder

    Directory of Open Access Journals (Sweden)

    Marcele Regine de Carvalho

    2013-12-01

    Full Text Available Some studies have reported the importance of electroencephalography (EEG as a method for investigating abnormal parameters in psychiatric disorders. Different findings in time and frequency domain analysis with regard to central nervous system arousal during acute panic states have already been obtained. This study aimed to systematically review the EEG findings in panic disorder (PD, discuss them having a currently accepted neuroanatomical hypothesis for this pathology as a basis, and identify limitations in the selected studies. Literature search was conducted in the databases PubMed and ISI Web of Knowledge, using the keywords electroencephalography and panic disorder; 16 articles were selected. Despite the inconsistency of EEG findings in PD, the major conclusions about the absolute power of alpha and beta bands point to a decreased alpha power, while beta power tends to increase. Different asymmetry patterns were found between studies. Coherence studies pointed to a lower degree of inter-hemispheric functional connectivity at the frontal region and intra-hemispheric at the bilateral temporal region. Studies on possible related events showed changes in memory processing in PD patients when exposed to aversive stimuli. It was noticed that most findings reflect the current neurobiological hypothesis of PD, where inhibitory deficits of the prefrontal cortex related to the modulation of amygdala activity, and the subsequent activation of subcortical regions, may be responsible to trigger anxiety responses. We approached some important issues that need to be considered in further researches, especially the use of different methods for analyzing EEG signals. Keywords: Electroencephalography, panic disorder, neurobiology, brain mapping.

  15. Critical Points in Distance Learning System

    Directory of Open Access Journals (Sweden)

    Airina Savickaitė

    2013-08-01

    Full Text Available Purpose – This article presents the results of distance learning system analysis, i.e. the critical elements of the distance learning system. The critical points of distance learning are a part of distance education online environment interactivity/community process model. The most important is the fact that the critical point is associated with distance learning participants. Design/methodology/approach – Comparative review of articles and analysis of distance learning module. Findings – A modern man is a lifelong learner and distance learning is a way to be a modern person. The focus on a learner and feedback is the most important thing of learning distance system. Also, attention should be paid to the lecture-appropriate knowledge and ability to convey information. Distance system adaptation is the way to improve the learner’s learning outcomes. Research limitations/implications – Different learning disciplines and learning methods may have different critical points. Practical implications – The information of analysis could be important for both lecturers and students, who studies distance education systems. There are familiar critical points which may deteriorate the quality of learning. Originality/value – The study sought to develop remote systems for applications in order to improve the quality of knowledge. Keywords: distance learning, process model, critical points. Research type: review of literature and general overview.

  16. Research on an uplink carrier sense multiple access algorithm of large indoor visible light communication networks based on an optical hard core point process.

    Science.gov (United States)

    Nan, Zhufen; Chi, Xuefen

    2016-12-20

    The IEEE 802.15.7 protocol suggests that it could coordinate the channel access process based on the competitive method of carrier sensing. However, the directionality of light and randomness of diffuse reflection would give rise to a serious imperfect carrier sense (ICS) problem [e.g., hidden node (HN) problem and exposed node (EN) problem], which brings great challenges in realizing the optical carrier sense multiple access (CSMA) mechanism. In this paper, the carrier sense process implemented by diffuse reflection light is modeled as the choice of independent sets. We establish an ICS model with the presence of ENs and HNs for the multi-point to multi-point visible light communication (VLC) uplink communications system. Considering the severe optical ICS problem, an optical hard core point process (OHCPP) is developed, which characterizes the optical CSMA for the indoor VLC uplink communications system. Due to the limited coverage of the transmitted optical signal, in our OHCPP, the ENs within the transmitters' carrier sense region could be retained provided that they could not corrupt the ongoing communications. Moreover, because of the directionality of both light emitting diode (LED) transmitters and receivers, theoretical analysis of the HN problem becomes difficult. In this paper, we derive the closed-form expression for approximating the outage probability and transmission capacity of VLC networks with the presence of HNs and ENs. Simulation results validate the analysis and also show the existence of an optimal physical carrier-sensing threshold that maximizes the transmission capacity for a given emission angle of LED.

  17. What Does It Mean to Be a Friendly Outsider? Critical Reflection on Finding a Role as an Action Researcher with Communities Developing Renewable Energy Projects

    Science.gov (United States)

    Rogers, Jennifer; Convery, Ian; Simmons, Eunice; Weatherall, Andrew

    2012-01-01

    This paper is a reflective account exploring the value of using action research in a relatively new context in the United Kingdom; the development of community renewable-energy projects. There is a strong rationale for using action research in this setting due to the synergies between the principles and practice of action research and localised…

  18. Historical overview of the synchrotron radiation research in Japan. From the view point of creative works in the development of light sources and related technology

    International Nuclear Information System (INIS)

    Kamitsubo, Hiromichi

    2007-01-01

    Synchrotron radiation research in Japan started in early 1960's when the first electron synchrotron was commissioned at the Institute of Nuclear Study (INS), University of Tokyo (UT). This review covers the parasite use of the INS electron synchrotron and research works done at the light sources in Japan such as SOR-RING, Photon Factory (KEK-PF) Accumulator Ring (KEK-AR), and SPring-8. History of synchrotron radiation research in Japan was overviewed by paying attention to the creative works in the development of light sources and related technology, as well as the pioneering works on the development of experimental techniques and methods. At present there are more than ten synchrotron radiation sources are in operation and the number of their users, especially users from industries in Japan is increasing very rapidly and the research fields of users are also developing. Accordingly the synchrotron radiation facility becomes more and more indispensable facility in the society in Japan. (author)

  19. Canadian Research Librarians have Little Time for Scholarship. A review of: Fox, David. “Finding Time for Scholarship: A Survey of Canadian Research University Librarians.” Portal: Libraries and the Academy 7.4 (2007: 451-62.

    Directory of Open Access Journals (Sweden)

    Pamela Haley

    2008-06-01

    responsibilities and 5% less time on scholarship. Participation rates in scholarship related leaves are low, with less than 25% of those surveyed engaging in these opportunities.Conclusion – Based on the study’s findings, research librarians are not participating in scholarship to any great degree due to the perceived lack of time.

  20. Parental decision-making on utilisation of out-of-home respite in children's palliative care: findings of qualitative case study research - a proposed new model.

    Science.gov (United States)

    Ling, J; Payne, S; Connaire, K; McCarron, M

    2016-01-01

    Respite in children's palliative care aims to provide a break for family's from the routine of caring. Parental decision-making regarding the utilisation of out-of-home respite is dependent on many interlinking factors including the child's age, diagnosis, geographical location and the family's capacity to meet their child's care needs. A proposed model for out-of-home respite has been developed based on the findings of qualitative case study research. Utilising multiple, longitudinal, qualitative case study design, the respite needs and experiences of parents caring for a child with a life-limiting condition were explored. Multiple, in-depth interviews were undertaken with the parents identified by a hospital-based children's palliative care team. Data were analysed using thematic analysis. Each individual case consists of a whole study. Cross-case comparison was also conducted. Nine families were recruited and followed for two years. A total of 19 in-depth interviews were conducted with mothers and fathers (one or both) caring for a child with a life-limiting condition in Ireland. Each family reported vastly different needs and experiences of respite from their own unique perspective. Cross-case comparison showed that for all parents utilising respite care, regardless of their child's age and condition, home was the location of choice. Many interlinking factors influencing these decisions included: past experience of in-patient care, and trust and confidence in care providers. Issues were raised regarding the impact of care provision in the home on family life, siblings and the concept of home. Respite is an essential element of children's palliative care. Utilisation of out-of-home respite is heavily dependent on a number of interlinked and intertwined factors. The proposed model of care offers an opportunity to identify how these decisions are made and may ultimately assist in identifying the elements of responsive and family-focused respite that are important

  1. Beam finding algorithms at the interaction point of B factories

    International Nuclear Information System (INIS)

    Kozanecki, W.

    1992-10-01

    We review existing methods to bring beams in collision in circular machines, and examine collision alignment strategies proposed for e + e - B-factories. The two-ring feature of such machines, while imposing more stringent demands on beam control, also opens up new diagnostic possibilities

  2. Point and track-finding processors for multiwire chambers

    CERN Document Server

    Hansroul, M

    1973-01-01

    The hardware processors described below are designed to be used in conjunction with multi-wire chambers. They have the characteristic of being based on computational methods in contrast to analogue procedures. In a sense, they are hardware implementations of computer programs. But, being specially designed for their purpose, they are free of the restrictions imposed by the architecture of the computer on which the equivalent program is to run. The parallelism inherent in the algorithms can thus be fully exploited. Combined with the use of fast access scratch-pad memories and the non-sequential nature of the control program, the parallelism accounts for the fact that these processors are expected to execute 2-3 orders of magnitude faster than the equivalent Fortran programs on a CDC 7600 or 6600. As a consequence, methods which are simple and straightforward, but which are impractical because they require an exorbitant amount of computer time can on the contrary be very attractive for hardware implementation. ...

  3. Research

    African Journals Online (AJOL)

    abp

    2013-03-11

    Mar 11, 2013 ... From a practical point of view, apart from the data on age that are easily obtained from recorded ..... Washington D.C. : Academy for Educational Development 2003. ... learning: data mining, inference and prediction. New York:.

  4. The Rossendorf research reactor. Operating and dismantling from a point of view of the emission control; Der Rossendorfer Forschungsreaktor. Betrieb und Rueckbau aus Sicht der Emissionsueberwachung

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, B.; Beutmann, A.; Kaden, M.; Scheibke, J. [VKTA, Dresden (Germany); Boessert, W.; Jansen, K.; Walter, M.

    2016-07-01

    The Rossendorf research reactor went in operation in 1957 as GDR's first nuclear reactor and Germanys second after FRM Garching. It was a heterogeneously structured, light-water moderated and cooled tank-reactor of the Soviet type WWR-S. During his time of operation, he served both the research and the production of radioisotopes. The history of exhaust air emission monitoring and its results are presented. With view to the decommissioning time selected results are discussed. The estimated discharges are compared by the actually recognized.

  5. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-03-02

    Mar 2, 2015 ... Joseph Daniels1,&, Ruth Nduati1,2, James Kiarie1,3, Carey Farquhar1,4,5 .... or basic science research career (Socio-Behavioral Research, .... a research environment that supports knowledge sharing to develop research ...

  6. The point on.

    International Nuclear Information System (INIS)

    1996-01-01

    In this last article, we find the point of view about the world petroleum activity, the reserves and the recent discoveries, the deep offshore, the technological developments in petroleum upstream. The petroleum situation in China is treated. The trends of world refining are described. The recent technological developments in the petroleum downstream are detailed. The prices of crude oil and the refining margins are the subject of a chapter. The investments of hydrocarbons area are given, the world trade and the lng projects, the gas availability in Western Europe have their place. The trends of European automobile industry and the fuels distribution are also discussed. (N.C.)

  7. What We Thought We Knew and How We Came to Know It: Four Decades of Cross-Cultural Research from a Piagetian Point of View

    Science.gov (United States)

    Maynard, Ashley E.

    2008-01-01

    The major tenets of Piagetian theory, such as adaptation and constructionism, are compatible with a cross-cultural approach to the study of cognitive development, but there have been significant methodological and theoretical advances over the past 40 years. Piagetian theory directly influenced three phases of cross-cultural research, ranging from…

  8. A Systematic Review of Consent Procedures, Participation Rates, and Main Findings of Health-Related Research in Alternative High Schools from 2010 to 2015

    Science.gov (United States)

    Johnson, Karen E.; Morris, Marian; Rew, Lynn; Simonton, Amanda J.

    2016-01-01

    There is a well-established link between educational attainment and health. Alternative high schools (AHSs) serve students who are at risk for school dropout. Health-related research conducted in AHSs has been sparse. Achieving high participation rates is critical to producing generalizable results and can be challenging in research with…

  9. Putting the Radical Notion of Equality in the Service of Disrupting Inequality in Education: Research Findings and Conceptual Advances on the Infinity of Human Potential

    Science.gov (United States)

    Stetsenko, Anna

    2017-01-01

    Research on disrupting inequality in education can benefit from situating it within the debates on varying and often conflicting meanings of equality and its perils and promises. Especially in the wake of achievement testing and resurgent biological determinism, researchers continue to equivocate between commitment to the idea that "all"…

  10. Translational Researchers' Perceptions of Data Management Practices and Data Curation Needs: Findings from a Focus Group in an Academic Health Sciences Library

    Science.gov (United States)

    Bardyn, Tania P.; Resnick, Taryn; Camina, Susan K.

    2012-01-01

    How translational researchers use data is becoming an important support function for libraries to understand. Libraries' roles in this increasingly complex area of Web librarianship are often unclearly defined. The authors conducted two focus groups with physicians and researchers at an academic medical center, the UCLA David Geffen School of…

  11. Cultural Attitudes and Body Dissatisfaction: Morgan State Researchers Find that Perceptions of Body Image among Young African Americans May Be Life Threatening

    Science.gov (United States)

    Hawkins, B. Denise

    2005-01-01

    Young African Americans don't appear to perceive obesity in the way the medical community does, putting them at greater risk for developing chronic diseases such as diabetes, hypertension and cancer, says a first-ever study led by researchers at the Morgan State University Prevention Sciences Research Center. The pilot study, which provides a rare…

  12. Mathematical points as didactical ideas

    DEFF Research Database (Denmark)

    Mogensen, Arne

    Mathematics teaching in Denmark was recently recommended better organized in sequences with clear mathematical pedagogical goals and a focus on mathematical points. In this paper I define a mathematical point and inform on coding of transcripts in a video based Danish research study on grade 8 te...

  13. The NIDDK Information Network: A Community Portal for Finding Data, Materials, and Tools for Researchers Studying Diabetes, Digestive, and Kidney Diseases.

    Directory of Open Access Journals (Sweden)

    Patricia L Whetzel

    Full Text Available The NIDDK Information Network (dkNET; http://dknet.org was launched to serve the needs of basic and clinical investigators in metabolic, digestive and kidney disease by facilitating access to research resources that advance the mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK. By research resources, we mean the multitude of data, software tools, materials, services, projects and organizations available to researchers in the public domain. Most of these are accessed via web-accessible databases or web portals, each developed, designed and maintained by numerous different projects, organizations and individuals. While many of the large government funded databases, maintained by agencies such as European Bioinformatics Institute and the National Center for Biotechnology Information, are well known to researchers, many more that have been developed by and for the biomedical research community are unknown or underutilized. At least part of the problem is the nature of dynamic databases, which are considered part of the "hidden" web, that is, content that is not easily accessed by search engines. dkNET was created specifically to address the challenge of connecting researchers to research resources via these types of community databases and web portals. dkNET functions as a "search engine for data", searching across millions of database records contained in hundreds of biomedical databases developed and maintained by independent projects around the world. A primary focus of dkNET are centers and projects specifically created to provide high quality data and resources to NIDDK researchers. Through the novel data ingest process used in dkNET, additional data sources can easily be incorporated, allowing it to scale with the growth of digital data and the needs of the dkNET community. Here, we provide an overview of the dkNET portal and its functions. We show how dkNET can be used to address a variety of use cases

  14. Research

    African Journals Online (AJOL)

    A descriptive qualitative research design was used to determine whether participants ... simulation as a teaching method; a manikin offering effective learning; confidence ..... Tesch R. Qualitative Research: Analysis Types and Software Tools.

  15. Impact of Combat Duty in Iraq and Afghanistan on Family Functioning: Findings from the Walter Reed Army Institute of Research Land Combat Study

    National Research Council Canada - National Science Library

    Huge, Charles W; Castro, Carl A; Eaton, Karen M

    2006-01-01

    .... However, most studies of the impact of combat on military families have not been conducted proximal to the time of deployments, and there are many research gaps in understanding the full impact of combat deployment...

  16. Research

    African Journals Online (AJOL)

    raoul

    2011-09-16

    Sep 16, 2011 ... discrimination was also good (Area Under Curve: 0.915, 95%CI: 0,901- 0,928). .... The median AHR were rounded to the nearest number to determine the points. ... Data management and statistical analysis. Statistical .... risk factors like the need to pay for treatment, macro-economic factors and limitations in ...

  17. Report on activities and findings under DOE grant “Collaborative research. An Interactive Multi-Model for Consensus on Climate Change”

    Energy Technology Data Exchange (ETDEWEB)

    Duane, Gregory S. [Univ. of Colorado, Boulder, CO (United States); Tsonis, Anastasios [Univ. of Wisconsin, Madison, WI (United States); Kocarev, Ljupco [Univ. of California, San Diego, CA (United States); Tribbia, Joseph [National Center for Atmospheric Research, Boulder, CO (United States)

    2015-10-30

    The project takes a hierarchical approach. The supermodeling scheme was first studied exhaustively with simple systems of ordinary differential equations. Results were described in detail in the previous report. The principal findings were that 1) for highly non-linear systems, such as Lorenz-63, including systems which describe phenomena on very different (atmosphere/ocean) times scales, supermodeling is far superior to any form of output-averaging; 2) negative coefficients can be used to advantage in situations where all models err in the same way, but to different degrees; 3) an interesting variant of supermodeling, “weighted supermodeling”, is the limiting case where inter-model nudging coefficients in the originally conceived “connected supermodel” become infinite, but with fixed ratios, corresponding to a direct combination of the tendencies that appear in corresponding equations for the alternative models; 4) noise is useful for avoiding local optima in training the inter-model coefficients in the supermodel. The supermodeling scheme was then investigated with simple quasigeostrophic (QG) models. As described in the previous report, it was found that QG models on a sphere can be coupled most efficaciously by working in a basis which captures the most variance, rather than the most instability, a somewhat unexpected result that still deserves scrutiny in a broader context. Further studies (since the last report) with QG channel models addressed the central question of when supermodeling is superior to output averaging in situations where nonlinearites are less extreme than with the ODEs initially studied. It was found that for realistic variations in a parameter in the QG model, output averaging is sufficient to capture all but the most subtle quantitative and qualitative behavior. Supermodeling helps when qualitative differences between the models result from unrealistically large parameter differences, or when very detailed spatial structure of the

  18. A Systematic Review of Consent Procedures, Participation Rates, and Main Findings of Health-Related Research in Alternative High Schools From 2010 to 2015.

    Science.gov (United States)

    Johnson, Karen E; Morris, Marian; Rew, Lynn; Simonton, Amanda J

    2016-02-01

    There is a well-established link between educational attainment and health. Alternative high schools (AHSs) serve students who are at risk for school dropout. Health-related research conducted in AHSs has been sparse. Achieving high participation rates is critical to producing generalizable results and can be challenging in research with adolescents for reasons such as using active consent. These challenges become greater when working with vulnerable populations of adolescents. In this systematic review, we examined health-related studies conducted in AHSs between 2010 and 2015. Results indicated that (1) health-related research in AHSs has increased over the past 5 years, (2) AHS students continue to experience significant disparities, (3) active consent is commonly used with AHS students, (4) 42% of studies reported participation rates or provided enough information to calculate participation rates, and (5) school nurses are missing from health-related research conducted in AHSs. Implications for future research and school nursing are discussed. © The Author(s) 2015.

  19. Research of the Rock Art from the point of view of geography: the neolithic painting of the Mediterranean area of the Iberian Peninsula

    Directory of Open Access Journals (Sweden)

    Cruz Berrocal, María

    2004-12-01

    Full Text Available The rock art of the Mediterranean Arch (which includes what are conventionally called Levantine Rock Art, Schematic Rock Art and Macroschematic Rock Art, among other styles, designated as part of the Human Heritage in 1997, is studied from the point of view of the Archaeology of Landscape. The information sources used were field work, cartographic analysis and analysis in GIS, besides two Rock Art Archives: the UNESCO Document and the Corpus of Levantine Cave Painting (Corpus de Pintura Rupestre Levantina. The initial hypothesis was that this rock art was involved in the process of neolithisation of the Eastern part of Iberia, of which it is a symptom and a result, and it must be understood as an element of landscape construction. If this is true, it would have a concrete distribution in the form of locational patterns. Through statistical procedures and heuristical approaches, it has been demonstrated that there is a structure of the neolithic landscape, defined by rock art, which is possible to interpret functional and economically.

    Se estudia el arte rupestre del Arco Mediterráneo (que incluye a los convencionalmente conocidos como Arte Levantino, Arte Esquemático y Arte Macroesquemático, entre otros estilos, nombrado Patrimonio de la Humanidad en 1998, desde el punto de vista de su localización. Las fuentes de información utilizadas fueron trabajo de campo, revisión cartográfica y análisis en Sistema de Información Geográfica, además de dos archivos de arte rupestre: el Expediente UNESCO y el Corpus de Pintura Rupestre Levantina. La hipótesis inicial fue que este arte rupestre se imbrica en el proceso de neolitización del Levante peninsular, del que es síntoma y resultado, y debe entenderse como un elemento de construcción paisajística, de lo que se deduce que ha de presentar una distribución determinable en forma de patrones locacionales. Por medio tanto de contrastes y descripciones estadísticas como de

  20. Non-financial constraints to scaling-up small and medium-sized energy enterprises: Findings from field research in Ghana, Senegal, Tanzania and Zambia

    DEFF Research Database (Denmark)

    Haselip, James Arthur; Desgain, Denis DR; Mackenzie, Gordon A.

    2015-01-01

    constraint to establishing and expanding local small and medium-sized energy businesses, a range of significant non-financial constraints were also identified. This article provides a critical evaluation of these non-financial constraints as they were encountered in Ghana, Senegal, Tanzania and Zambia, based...... on the findings of a wider study into the key outcomes of the AREED project. These barriers include the institutional frameworks, human capacities and social and cultural factors....