WorldWideScience

Sample records for research council trial

  1. [Population Council responsible for RU486 clinical trials in USA].

    Science.gov (United States)

    Aguillaume, C J

    1993-04-01

    As a result of the sudden political change that came with the Clinton Administration, RU-486's manufacturer, Roussel-Uclaf, and the Population Council agreed on April 20, 1992, on the manufacture and distribution of RU-486 in the US. In the US, there are less than 1.6 million induced abortions annually. From now on, US women will be able to have a choice between medical and surgical abortion. The Population Council and Roussel-Uclaf have had a contract since 1982. The Council is solely responsible for the phase 2 clinical trial of RU-486 in the US and other countries. It must present to the US Food and Drug Administration (FDA) an amendment allowing it to begin phase 3 clinical trials. The Council will also lead the US medical facilities in this study. It will identify partners for future production of RU-486 and its distribution in the US. It will also submit to FDA a New Drug Application (NDA). FDA will review the scientific literature on RU-486 and evaluate all data submitted by the Population Council. There are still obstacles to be surmounted. The Population Council must demonstrate good judgment when selecting the criteria for choosing a pharmaceutical firm before a Technical Committee which will be part of a group of players promoting women's health, scientific experts, and other interested parties. It must find the necessary funds to conduct the clinical trials and prepare the NDA. Phase 3 clinical trials in the US must have at least 2000 women. They will test RU-486's efficacy, safety, and acceptability among women choosing medical abortion over surgical abortion. Since the Council operates in almost all countries in the world, has innovated contraceptive research and development activities, and has been endorsed by the UN, product approval of RU-486 in the US will affect policy in all countries concerned about abortion.

  2. Involvement of consumers in studies run by the Medical Research Council Clinical Trials Unit: Results of a survey

    Directory of Open Access Journals (Sweden)

    Vale Claire L

    2012-01-01

    Full Text Available Abstract Background We aimed to establish levels of consumer involvement in randomised controlled trials (RCTs, meta-analyses and other studies carried out by the UK Medical Research Council (MRC Clinical Trials Unit across the range of research programs, predominantly in cancer and HIV. Methods Staff responsible for studies that were included in a Unit Progress Report (MRC CTU, April 2009 were asked to complete a semi-structured questionnaire survey regarding consumer involvement. This was defined as active involvement of consumers as partners in the research process and not as subjects of that research. The electronic questionnaires combined open and closed questions, intended to capture quantitative and qualitative information on whether studies had involved consumers; types of activities undertaken; recruitment and support; advantages and disadvantages of involvement and its perceived impact on aspects of the research. Results Between October 2009 and April 2010, 138 completed questionnaires (86% were returned. Studies had been conducted over a 20 year period from 1989, and around half were in cancer; 30% in HIV and 20% were in other disease areas including arthritis, tuberculosis and blood transfusion medicine. Forty-three studies (31% had some consumer involvement, most commonly as members of trial management groups (TMG [88%]. A number of positive impacts on both the research and the researcher were identified. Researchers generally felt involvement was worthwhile and some felt that consumer involvement had improved the credibility of the research. Benefits in design and quality, trial recruitment, dissemination and decision making were also perceived. Researchers felt they learned from consumer involvement, albeit that there were some barriers. Conclusions Whilst most researchers identified benefits of involving consumers, most of studies included in the survey had no involvement. Information from this survey will inform the development

  3. Involvement of consumers in studies run by the Medical Research Council Clinical Trials Unit: results of a survey.

    Science.gov (United States)

    Vale, Claire L; Thompson, Lindsay C; Murphy, Claire; Forcat, Silvia; Hanley, Bec

    2012-01-13

    We aimed to establish levels of consumer involvement in randomised controlled trials (RCTs), meta-analyses and other studies carried out by the UK Medical Research Council (MRC) Clinical Trials Unit across the range of research programs, predominantly in cancer and HIV. Staff responsible for studies that were included in a Unit Progress Report (MRC CTU, April 2009) were asked to complete a semi-structured questionnaire survey regarding consumer involvement. This was defined as active involvement of consumers as partners in the research process and not as subjects of that research. The electronic questionnaires combined open and closed questions, intended to capture quantitative and qualitative information on whether studies had involved consumers; types of activities undertaken; recruitment and support; advantages and disadvantages of involvement and its perceived impact on aspects of the research. Between October 2009 and April 2010, 138 completed questionnaires (86%) were returned. Studies had been conducted over a 20 year period from 1989, and around half were in cancer; 30% in HIV and 20% were in other disease areas including arthritis, tuberculosis and blood transfusion medicine. Forty-three studies (31%) had some consumer involvement, most commonly as members of trial management groups (TMG) [88%]. A number of positive impacts on both the research and the researcher were identified. Researchers generally felt involvement was worthwhile and some felt that consumer involvement had improved the credibility of the research. Benefits in design and quality, trial recruitment, dissemination and decision making were also perceived. Researchers felt they learned from consumer involvement, albeit that there were some barriers. Whilst most researchers identified benefits of involving consumers, most of studies included in the survey had no involvement. Information from this survey will inform the development of a unit policy on consumer involvement, to guide future

  4. Foresight and strategy in national research councils and research programmes

    DEFF Research Database (Denmark)

    Andersen, Per Dannemand; Borup, Mads

    2009-01-01

    This paper addresses the issue of foresight and strategy processes of national research councils and research programmes. It is based on a study of strategy processes in national research councils and programmes and the challenges faced by their strategy activities. We analysed the strategy...... processes of two organisations: the Danish Technical Research Council and the Danish Energy Research Programme. We analysed the mechanisms of the strategy processes and studied the actors involved. The actors’ understanding of strategy was also included in the analysis. Based on these analyses we argue...... that the impact of foresight exercises can be improved if we have a better understanding of the traditions and new challenges faced by the research councils. We also argue that a more formal use of foresight elements might improve the legitimacy and impact of the strategic considerations of research councils...

  5. Wood Protection Research Council: Research Priorities 2013

    Science.gov (United States)

    Carol A Clausen; Frederick Green III; Grant T. Kirker; Stan T. Lebow

    2014-01-01

    This report summarizes presentations and comments from the inaugural Wood Protection Research Council meeting. Research needs for the wood protection industry were identified and prioritized. Methods for successfully addressing research needs were discussed by industry, academia, and association representatives.

  6. The Swedish Research Councils' Laboratory progress report for 1975

    International Nuclear Information System (INIS)

    Rudstam, G.

    1976-01-01

    The Swedish Research Councils' Laboratory herewith presents its progress report for 1975. The report summarizes the current projects carried out by the research groups working at the laboratory. The very efficient assistance of the staff of the laboratory is greatfully acknowledged. The laboratory has been financially supported by the Atomic Research Council, the Medical Research Council, the Natural Science Research Council, and the Board of Technical Development. Valuable support in various ways has also been given by the Atomic Energy Company (AB Atomenergi). (author)

  7. Hewitt launches Research Councils UK

    CERN Multimedia

    2002-01-01

    "Trade and Industry Secretary Patricia Hewitt today launched 'Research Councils UK' - a new strategic partnership that will champion research in science, engineering and technology across the UK" (1 page).

  8. The value of Internet research to Danish council reporters

    DEFF Research Database (Denmark)

    Sparre, Kirsten

    2008-01-01

    This article presents the findings from qualitative interviews with nine Danish council reporters on how they use the Internet for research on council affairs. Through qualitative interviews, the article aims to qualify and expand findings from survey research on journalists' use of the Internet...... for research and asks how much value journalists add to information found on the Internet and how important Internet research is compared to other types of research. The journalists interviewed found that the council website was useful as a provider of factual information about the council and a searchable...

  9. EPERC: The European Pressure Equipment Research Council

    International Nuclear Information System (INIS)

    Darlaston, J.; McAllister, S.

    1998-01-01

    The European Pressure Equipment Research Council (EPERC) is a European Network of industries, research laboratories, inspection bodies and governmental institutions set up to foster co-operative research for the greater benefit of the European industry. The concept of a European Research Council originated at the PVRC meeting in Cannes in 1989 and since this time volunteers from the industry, research laboratories and of the European Commission Joint Research Centre, Petten have worked together to create a Statute for EPERC. In the context of the pressure equipment industry, the creation of EPERC is extremely pertinent, since in the near future, a Council directive on pressure equipment will replace the existing national regulations. In parallel to this, work is in progress for the elaboration of European Standards. It is useful to recall that ''Harmonised Standards'' will be the privileged means of complying with the Essential Safety Requirements of the directive. (author)

  10. International fusion research council

    International Nuclear Information System (INIS)

    Belozerov, A.N.

    1977-01-01

    A brief history of the International Fusion Research Council (IFRC) is given and the minutes of the 1976 meeting in Garching are summarized. At the Garching meeting, the IFRC evaluated the quality of papers presented at recent IAEA conferences on plasma physics and controlled thermonuclear research, and made recommendations on the organization and timing of future meetings on nuclear fusion

  11. Research council faces financial ‘catastrophe’

    Science.gov (United States)

    Catanzaro, Michele

    2013-08-01

    Spain’s biggest scientific institution - the Spanish National Research Council (CSIC) - has announced it is in financial difficulty and that it has already clawed back unspent cash for research projects funded before 2012 in order to survive until October.

  12. Using the Medical Research Council framework for the development and evaluation of complex interventions in a theory-based infant feeding intervention to prevent childhood obesity: the baby milk intervention and trial.

    Science.gov (United States)

    Lakshman, Rajalakshmi; Griffin, Simon; Hardeman, Wendy; Schiff, Annie; Kinmonth, Ann Louise; Ong, Ken K

    2014-01-01

    We describe our experience of using the Medical Research Council framework on complex interventions to guide the development and evaluation of an intervention to prevent obesity by modifying infant feeding behaviours. We reviewed the epidemiological evidence on early life risk factors for obesity and interventions to prevent obesity in this age group. The review suggested prevention of excess weight gain in bottle-fed babies and appropriate weaning as intervention targets; hence we undertook systematic reviews to further our understanding of these behaviours. We chose theory and behaviour change techniques that demonstrated evidence of effectiveness in altering dietary behaviours. We subsequently developed intervention materials and evaluation tools and conducted qualitative studies with mothers (intervention recipients) and healthcare professionals (intervention deliverers) to refine them. We developed a questionnaire to assess maternal attitudes and feeding practices to understand the mechanism of any intervention effects. In addition to informing development of our specific intervention and evaluation materials, use of the Medical Research Council framework has helped to build a generalisable evidence base for early life nutritional interventions. However, the process is resource intensive and prolonged, and this should be taken into account by public health research funders. This trial is registered with ISRTCN: 20814693 Baby Milk Trial.

  13. Using the Medical Research Council Framework for the Development and Evaluation of Complex Interventions in a Theory-Based Infant Feeding Intervention to Prevent Childhood Obesity: The Baby Milk Intervention and Trial

    Directory of Open Access Journals (Sweden)

    Rajalakshmi Lakshman

    2014-01-01

    Full Text Available Introduction. We describe our experience of using the Medical Research Council framework on complex interventions to guide the development and evaluation of an intervention to prevent obesity by modifying infant feeding behaviours. Methods. We reviewed the epidemiological evidence on early life risk factors for obesity and interventions to prevent obesity in this age group. The review suggested prevention of excess weight gain in bottle-fed babies and appropriate weaning as intervention targets; hence we undertook systematic reviews to further our understanding of these behaviours. We chose theory and behaviour change techniques that demonstrated evidence of effectiveness in altering dietary behaviours. We subsequently developed intervention materials and evaluation tools and conducted qualitative studies with mothers (intervention recipients and healthcare professionals (intervention deliverers to refine them. We developed a questionnaire to assess maternal attitudes and feeding practices to understand the mechanism of any intervention effects. Conclusions. In addition to informing development of our specific intervention and evaluation materials, use of the Medical Research Council framework has helped to build a generalisable evidence base for early life nutritional interventions. However, the process is resource intensive and prolonged, and this should be taken into account by public health research funders. This trial is registered with ISRTCN: 20814693 Baby Milk Trial.

  14. Lord Sainsbury announces outcome of Research Council review

    CERN Multimedia

    Dept. Trade & Industry

    2002-01-01

    Science and Innovation Minister, Lord Sainsbury, today announced the outcome of a review of the Council for the Central Laboratory of the Research Councils (CCLRC). The report is the second stage of a five-yearly review, which outlines ways to strengthen and promote greater value for money from the UK's investment in science (1 page).

  15. 78 FR 30847 - Forestry Research Advisory Council

    Science.gov (United States)

    2013-05-23

    ..., Forestry Research Advisory Council, USDA Forest Service Research and Development, Mail Stop 1120, 1400... Service Office of the Deputy Chief for Research and Development, 202-205-1665. Individuals who use telecommunication devices for the deaf (TDD) may call the Federal Information Relay Service (FIRS) at 1-800-877-8339...

  16. Report of the Science and Engineering Research Council, 1 April 1993 - 31 March 1994

    International Nuclear Information System (INIS)

    1994-01-01

    This final Annual Report of the Science and Engineering Research Council (SERC) covers the work of the organization for 1993-1994 and explains the structures and missions of the organizations which replace it. SERC funds and supports United Kingdom research programs covering many aspects of science and engineering. Its work will be split between the new Engineering and Physical Sciences Research Council, the Particle Physics and Astronomy Research Council, the Biotechnology and Biological Sciences Research Council and the Natural Environment Research Council. Research achievements and training initiatives are reported for each of SERC's current Boards. (UK)

  17. Writing a Research Proposal to The Research Council of Oman

    OpenAIRE

    Al-Shukaili, Ahmed; Al-Maniri, Abdullah

    2017-01-01

    Writing a research proposal can be a challenging task for young researchers. This article explains how to write a strong research proposal to apply for funding, specifically, a proposal for The Research Council (TRC) of Oman. Three different research proposal application forms are currently used in TRC, including Open Research Grant (ORG), Graduate Research Support Program (GRSP), and Faculty-mentored Undergraduate Research Award Program (FURAP). The application forms are filled and submitted...

  18. 77 FR 26734 - Forestry Research Advisory Council

    Science.gov (United States)

    2012-05-07

    ... and proposals by May 31, 2012 to Daina Apple, Designated Federal Officer, Forestry Research Advisory...: Daina Apple, Forest Service, Office of the Deputy Chief for Research and Development, (202) 205-1665. SUPPLEMENTARY INFORMATION: The meeting is open to the public. Council discussion is limited to Forest Service...

  19. Maximising the value of combining qualitative research and randomised controlled trials in health research: the QUAlitative Research in Trials (QUART) study--a mixed methods study.

    Science.gov (United States)

    O'Cathain, Alicia; Thomas, Kate J; Drabble, Sarah J; Rudolph, Anne; Goode, Jackie; Hewison, Jenny

    2014-06-01

    Researchers sometimes undertake qualitative research with randomised controlled trials (RCTs) of health interventions. To systematically explore how qualitative research is being used with trials and identify ways of maximising its value to the trial aim of providing evidence of effectiveness of health interventions. A sequential mixed methods study with four components. (1) Database search of peer-reviewed journals between January 2008 and September 2010 for articles reporting the qualitative research undertaken with specific trials, (2) systematic search of database of registered trials to identify studies combining qualitative research and trials, (3) survey of 200 lead investigators of trials with no apparent qualitative research and (4) semistructured telephone interviews with 18 researchers purposively sampled from the first three methods. Qualitative research was undertaken with at least 12% of trials. A large number of articles reporting qualitative research undertaken with trials (n=296) were published between 2008 and 2010. A total of 28% (82/296) of articles reported qualitative research undertaken at the pre-trial stage and around one-quarter concerned drugs or devices. The articles focused on 22 aspects of the trial within five broad categories. Some focused on more than one aspect of the trial, totalling 356 examples. The qualitative research focused on the intervention being trialled (71%, 254/356), the design and conduct of the trial (15%, 54/356), the outcomes of the trial (1%, 5/356), the measures used in the trial (3%, 10/356), and the health condition in the trial (9%, 33/356). The potential value of the qualitative research to the trial endeavour included improving the external validity of trials and facilitating interpretation of trial findings. This value could be maximised by using qualitative research more at the pre-trial stage and reporting findings with explicit attention to the implications for the trial endeavour. During interviews

  20. 78 FR 2950 - Forestry Research Advisory Council

    Science.gov (United States)

    2013-01-15

    ... Advisory Council, USDA Forest Service Research and Development, Mail Stop 1120, 1400 Independence Ave. SW... of the Deputy Chief for Research and Development, 202-205-1665. Individuals who use telecommunication devices for the deaf (TDD) may call the Federal Information Relay Service (FIRS) at 1-800-877-8339 between...

  1. IRIS and the National Research Council (NRC)

    Science.gov (United States)

    Since the 2011 National Academies’ National Research Council (NRC) review of the IRIS Program's assessment of Formaldehyde, EPA and NRC have had an ongoing relationship into the improvements of developing the IRIS Assessments.

  2. Annual report of the Science and Engineering Research Council 1992-1993

    International Nuclear Information System (INIS)

    1993-01-01

    Details of expenditure and reports of the activities of the four Boards which operate as the Science and Engineering Research Council are given. These are the Astronomical and Planetry Science Board, the Engineering Board, the Nuclear Physics Board and the Science Board. There is also a report on the optical physics and optoelectronic research supported by the Council. Committee membership, studentship, fellowships research grants and administration details are reported. (UK)

  3. 76 FR 43651 - Forestry Research Advisory Council

    Science.gov (United States)

    2011-07-21

    ... send their names and proposals by August 1, 2011 to Daina Apple, Designated Federal Officer, Forestry... INFORMATION CONTACT: Daina Apple, Forest Service Office of the Deputy Chief for Research and Development, (202) 205-1665. SUPPLEMENTARY INFORMATION: The meeting is open to the public. Council discussion is limited...

  4. Building Digital Economy - The Research Councils Programme and the Vision

    Science.gov (United States)

    Hand, John

    We at the Research Councils believe that there are many aspects of society and business that could be transformed by the innovative design and use of digital technologies. This has led to the Digital Economy Programme. The Digital Economy is an RCUK Cross-Research Council Programme, led by the EPSRC, but working closely with ESRC, MRC, AHRC and TSB. What is Digital Economy? Digital Economy is the novel design or use of information and communication technology to help transform the lives of individuals, society or business. All Digital Economy research involves the user community. This can include industry, government, society, charities or other groups as applicable. The research will understand the technologies and also why change is needed, what the impacts will be and who will benefit. Research in this cross-research council area can be driven by economic, social or technical need. The early involvement of the user community is vital if new technologies are to be integrated successfully into business opportunities, technical solutions or commercial products and processes. Challenges in the Digital Economy will require multi-disciplinary academic input, including, but not limited to, the arts and humanities, economic and social sciences and medical sciences, in addition to engineering and physical sciences.

  5. Questions raised over future of UK research council

    Science.gov (United States)

    Banks, Michael

    2010-02-01

    Five senior physicists have written to the UK science minister, Lord Drayson, about the "dismal future" for researchers in the country in the wake of a £40m shortfall in the budget of the Science and Technology Facilities Council (STFC). The physicists, who chair the STFC's five advisory panels, have also called for structural reforms to be made to the council. They warn that unless the government takes action to reverse the situation, the UK will be "perceived as an untrustworthy partner in global projects" and predict that a brain drain of the best UK scientists to positions overseas will ensue.

  6. [Antibiotic resistance: recommendations from the Advisory Council for Health Research

    NARCIS (Netherlands)

    Hoogkamp-Korstanje, J.A.A.

    2001-01-01

    The Advisory Council for Health Research (RGO) advised the Dutch Minister of Health on research into the epidemiology, prevention and research of antibiotic resistance in the Netherlands. Good antimicrobial practice, insight into antibiotic use, implementation of measures to prevent development of

  7. Models and impact of patient and public involvement in studies carried out by the Medical Research Council Clinical Trials Unit at University College London: findings from ten case studies.

    Science.gov (United States)

    South, Annabelle; Hanley, Bec; Gafos, Mitzy; Cromarty, Ben; Stephens, Richard; Sturgeon, Kate; Scott, Karen; Cragg, William J; Tweed, Conor D; Teera, Jacqueline; Vale, Claire L

    2016-07-29

    Patient and public involvement (PPI) in studies carried out by the UK Medical Research Council Clinical Trials Unit (MRC CTU) at University College London varies by research type and setting. We developed a series of case studies of PPI to document and share good practice. We used purposive sampling to identify studies representing the scope of research at the MRC CTU and different approaches to PPI. We carried out semi-structured interviews with staff and patient representatives. Interview notes were analysed descriptively to categorise the main aims and motivations for involvement; activities undertaken; their impact on the studies and lessons learned. We conducted 19 interviews about ten case studies, comprising one systematic review, one observational study and 8 randomised controlled trials in HIV and cancer. Studies were either open or completed, with start dates between 2003 and 2011. Interviews took place between March and November 2014 and were updated in summer 2015 where there had been significant developments in the study (i.e. if the study had presented results subsequent to the interview taking place). A wide range of PPI models, including representation on trial committees or management groups, community engagement, one-off task-focused activities, patient research partners and participant involvement had been used. Overall, interviewees felt that PPI had a positive impact, leading to improvements, for example in the research question; study design; communication with potential participants; study recruitment; confidence to carry out or complete a study; interpretation and communication of results; and influence on future research. A range of models of PPI can benefit clinical studies. Researchers should consider different approaches to PPI, based on the desired impact and the people they want to involve. Use of multiple models may increase the potential impacts of PPI in clinical research.

  8. Exploring the Best Practices of Nursing Research Councils in Magnet® Organizations: Findings From a Qualitative Research Study.

    Science.gov (United States)

    Day, Jennifer; Lindauer, Cathleen; Parks, Joyce; Scala, Elizabeth

    2017-05-01

    The objective of this descriptive qualitative study was to identify best practices of nursing research councils (NRCs) at Magnet®-designated hospitals. Nursing research (NR) is essential, adding to the body of nursing knowledge. Applying NR to the bedside improves care, enhances patient safety, and is an imperative for nursing leaders. We interviewed NR designees at 26 Magnet-recognized hospitals about the structure and function of their NRCs and used structural coding to identify best practices. Most organizations link NR and evidence-based practice. Council membership includes leadership and clinical nurses. Councils conduct scientific reviews for nursing studies, supporting nurse principal investigators. Tracking and reporting of NR vary widely and are challenging. Councils provide education, sponsor research days, and collaborate interprofessionally, including with academic partners. Findings from this study demonstrate the need to create formal processes to track and report NR and to develop outcome-focused NR education.

  9. How the Recovery Act's Federal Coordinating Council paved the way for the Patient-Centered Outcomes Research Institute.

    Science.gov (United States)

    Conway, Patrick H

    2010-11-01

    The American Recovery and Reinvestment Act of 2009 provided $1.1 billion for comparative effectiveness research and established the Federal Coordinating Council for Comparative Effectiveness Research to direct that investment. The council laid a critical foundation for comparative effectiveness research in the steps it took to gather information, invite public input, set priorities, coordinate project solicitations, and stress the importance of evaluating research investments. Although the council has been superseded by a successor--the Patient-Centered Outcomes Research Institute--the experiences of the council can and should inform the work of the new institute as it begins its operations.

  10. 78 FR 15928 - Forestry Research Advisory Council

    Science.gov (United States)

    2013-03-13

    ... apportionment of funds. Advisory Council Organization The Council will be comprised of not more than 20 members. The members appointed to the Council will be fairly balanced in terms of the points of view... relevancy to a membership category. Geographic balance and a balanced distribution among the categories are...

  11. Educating for a Critical Democracy: Civic Participation Reimagined in the Council of Youth Research

    Science.gov (United States)

    Mirra, Nicole; Morrell, Ernest D.; Cain, Ebony; Scorza, D'Artagnan; Ford, Arlene

    2013-01-01

    This article explores civic learning, civic participation, and the development of civic agency within the Council of Youth Research (the Council), a program that engages high school students in youth participatory action research projects that challenge school inequalities and mobilize others in pursuit of educational justice. We critique the…

  12. 75 FR 14131 - Effect on Propane Consumers of the Propane Education and Research Council's Operations, Market...

    Science.gov (United States)

    2010-03-24

    ... Propane Education and Research Council's Operations, Market Changes and Federal Programs AGENCY... Education and Research Council (PERC), in conjunction with the cumulative effects of market changes and... requirements under the Propane Education and Research Act of 1996 that established PERC and requires the...

  13. The hazards to man of nuclear and allied radiations. A second report to the Medical Research Council

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1960-12-01

    In March, 1955, the Prime Minister requested that the Medical Research Council should appoint an independent committee to report on the medical and genetic aspects of nuclear radiation and in the following month the Council appointed us members of such a committee, under the chairmanship of Sir Harold Himsworth, to undertake this task. In June, 1956, our Report to the Medical Research Council (Cmd. 9780) was presented to Parliament by the Lord President of the Council. In the following months our Genetics Panel met twice for the primary purpose of putting forward further recommendations for research and in June, 1958, we ourselves, at the Council's request, met again in full session to prepare a statement (Cmnd. 508) on the Report of the United Nations Scientific Committee on the Effects of Atomic Radiation. During the whole of this period the subject has been kept under regular review by various standing committees of the Council. We ourselves met again in November, 1959, following a request from the Medical Research Council that we should prepare a further considered statement of the position in this field and the report which follows is the result of this request.

  14. The hazards to man of nuclear and allied radiations. A second report to the Medical Research Council

    International Nuclear Information System (INIS)

    1960-12-01

    In March, 1955, the Prime Minister requested that the Medical Research Council should appoint an independent committee to report on the medical and genetic aspects of nuclear radiation and in the following month the Council appointed us members of such a committee, under the chairmanship of Sir Harold Himsworth, to undertake this task. In June, 1956, our Report to the Medical Research Council (Cmd. 9780) was presented to Parliament by the Lord President of the Council. In the following months our Genetics Panel met twice for the primary purpose of putting forward further recommendations for research and in June, 1958, we ourselves, at the Council's request, met again in full session to prepare a statement (Cmnd. 508) on the Report of the United Nations Scientific Committee on the Effects of Atomic Radiation. During the whole of this period the subject has been kept under regular review by various standing committees of the Council. We ourselves met again in November, 1959, following a request from the Medical Research Council that we should prepare a further considered statement of the position in this field and the report which follows is the result of this request

  15. Forging Links for Health Research: Perspectives from the Council on ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    As part of the lead up to the October 2000 International Conference on Health Research for Development in Bangkok, the Council on Health Research for Development (COHRED) called upon its associates around the world to reflect on achievements and setbacks in the 1990s. This book is the result of those reflections.

  16. Participant verification: Prevention of co‑enrolment in clinical trials in ...

    African Journals Online (AJOL)

    Methods. The Medical Research Council (MRC) HIV Prevention Research ... which uses fingerprint-based biometric technology to identify participants. ... and clinical trial sites, with new participant information loaded at first visit to a trial site.

  17. Science councils in South Africa

    CSIR Research Space (South Africa)

    Scholes, RJ

    2008-11-01

    Full Text Available for Scien- tific and Industrial Research (CSIR), the Medical Research Council, Agricultural Research Council, Human Sciences Research Council, Council for Geosciences, Mintek, and the Nuclear Energy Corporation of SA. Legally, it includes the National... with social or commercial impact is long and uncer- tain, and becomes more and more expen- sive the closer the development gets to implementation. It is hard for a single organization to span this entire contin- uum effectively—it requires ‘interfacial...

  18. 75 FR 24773 - Research and Innovative Technology Administration Advisory Council on Transportation Statistics...

    Science.gov (United States)

    2010-05-05

    ... DEPARTMENT OF TRANSPORTATION Bureau of Transportation Statistics Research and Innovative Technology Administration Advisory Council on Transportation Statistics; Notice of Meeting AGENCY: Research... Transportation, Research and Innovative Technology Administration, Bureau of Transportation Statistics, Attention...

  19. Modifying the Medical Research Council grading system through Rasch analyses

    NARCIS (Netherlands)

    Vanhoutte, Els Karla; Faber, Catharina Gerritdina; van Nes, Sonja Ingrid; Jacobs, Bart Casper; van Doorn, Pieter Antoon; van Koningsveld, Rinske; Cornblath, David Reid; van der Kooi, Anneke Jelly; Cats, Elisabeth Aviva; van den Berg, Leonard Hendrik; Notermans, Nicolette Claudia; van der Pol, Willem Lodewijk; Hermans, Mieke Catharina Elisabeth; van der Beek, Nadine Anna Maria Elisabeth; Gorson, Kenneth Craig; Eurelings, Marijke; Engelsman, Jeroen; Boot, Hendrik; Meijer, Ronaldus Jacobus; Lauria, Giuseppe; Tennant, Alan; Merkies, Ingemar Sergio José; Barreira, A. A.; Bennett, D.; van den Bergh, P. Y. K.; Bril, V.; Devigili, G.; Hadden, R. D.; Hahn, A. F.; Hartung, H.-P.; Hughes, R. A. C.; Illa, I.; Katzberg, H.; Léger, J.-M.; Lewis, R. A.; Lunn, M. P. T.; Nascimento, O. J. M.; Nobile-Orazio, E.; Padua, L.; Pouget, J.; Reilly, M. M.; van Schaik, I.; Smith, B.; de Visser, M.; Walk, D.

    2012-01-01

    The Medical Research Council grading system has served through decades for the evaluation of muscle strength and has been recognized as a cardinal feature of daily neurological, rehabilitation and general medicine examination of patients, despite being respectfully criticized due to the unequal

  20. Modifying the Medical Research Council grading system through Rasch analyses

    NARCIS (Netherlands)

    E.K. Vanhoutte (Els); C.G. Faber (Carin); S.I. van Nes (Sonja); B.C. Jacobs (Bart); P.A. van Doorn (Pieter); R. van Koningsveld (Rinske); D.R. Cornblath (David); A.J. Kooj (Anneke); E.A. Cats (Elisabeth); L.H. van den Berg (Leonard); N.C. Notermans (Nicolette); W.L. van der Pol (Ludo); M.C.E. Hermans; N.A.M.E. van der Beek (Nadine); K.C. Gorson (Kenneth); M. Eurelings (Marijke); L. Engelsman (Lyda); H. Boot (Hendrik); R.J. Meijer (Ron); G. Lauria (Giuseppe); C. Tennant (Christopher); I.S.J. Merkies (Ingemar)

    2012-01-01

    textabstractThe Medical Research Council grading system has served through decades for the evaluation of muscle strength and has been recognized as a cardinal feature of daily neurological, rehabilitation and general medicine examination of patients, despite being respectfully criticized due to the

  1. 75 FR 55634 - National Research Advisory Council; Notice of Meeting

    Science.gov (United States)

    2010-09-13

    ... DEPARTMENT OF VETERANS AFFAIRS National Research Advisory Council; Notice of Meeting The Department of Veterans Affairs (VA) gives notice under Public Law 92-463 (Federal Advisory Committee Act... Phoenix Park Hotel, Federal City Room, 520 North Capitol Street, NW., Washington, DC. The meeting will...

  2. Writing a Research Paper for Journal of Nepal Agricultural Research Council

    Directory of Open Access Journals (Sweden)

    Bal Krishna Joshi

    2018-05-01

    Full Text Available Agricultural research findings are required to reach soon to the farmers, extensionists, media, researchers, policy makers, businessperson, students, teachers and so many other stakeholders. Among different types of publications, research paper is generally published in journal considered as standard type of publication in term of quality and recognition. Most of the journals follow similar pattern and framework; however, the style, format and process may be different with each other. A research (scientific paper is a written describing original research result using standard methods and materials. The major sections in a journal paper are abstract, introduction, materials and methods, results, discussion, conclusion, and references. Accordingly Journal of Nepal Agricultural Research Council has its own style and format. Author needs to follow guidelines strictly on the use of punctuation marks such as comma (,, period (., space, justification etc; otherwise submitted manuscripts could be immediately return to author without considering in review process. In general, we received manuscripts with many errors on citation and references, poor elaboration of results of experiments, weak discussion, missing to acknowledge funding agencies, submitting non-editable figures, very few numbers of citations of Nepalese researchers, statements not in logical order, etc. In general, the scientific papers should be written in simple way with new but sufficient justification backed up by data in the form of tables, graphs, flow diagrams etc so that readers can understand easily with high readability. The submitted manuscript in the journal office are sent to two to three reviewers for specific recommendation on the originality of the work, appropriateness of the approach and experimental design, adequacy of experimental techniques, soundness of conclusions and interpretations, relevance of discussion and importance of the research. The language clarity and

  3. Writing a Research Proposal to The Research Council of Oman.

    Science.gov (United States)

    Al-Shukaili, Ahmed; Al-Maniri, Abdullah

    2017-05-01

    Writing a research proposal can be a challenging task for young researchers. This article explains how to write a strong research proposal to apply for funding, specifically, a proposal for The Research Council (TRC) of Oman. Three different research proposal application forms are currently used in TRC, including Open Research Grant (ORG), Graduate Research Support Program (GRSP), and Faculty-mentored Undergraduate Research Award Program (FURAP). The application forms are filled and submitted electronically on TRC website. Each of the proposals submitted to TRC is selected through a rigorous reviewing and screening process. Novelty and originality of the research idea is the most crucial element in writing a research proposal. Performing an in-depth review of the literature will assist you to compose a good researchable question and generate a strong hypothesis. The development of a good hypothesis will offer insight into the specific objectives of a study. Research objectives should be focused, measurable, and achievable by a specific time using the most appropriate methodology. Moreover, it is essential to select a proper study design in-line with the purpose of the study and the hypothesis. Furthermore, social/economic impact and reasonable budget of proposed research are important criteria in research proposal evaluation by TRC. Finally, ethical principles should be observed before writing a research proposal involving human or animal subjects.

  4. Writing a Research Proposal to The Research Council of Oman

    Directory of Open Access Journals (Sweden)

    Ahmed Al-Shukaili

    2017-05-01

    Full Text Available Writing a research proposal can be a challenging task for young researchers. This article explains how to write a strong research proposal to apply for funding, specifically, a proposal for The Research Council (TRC of Oman. Three different research proposal application forms are currently used in TRC, including Open Research Grant (ORG, Graduate Research Support Program (GRSP, and Faculty-mentored Undergraduate Research Award Program (FURAP. The application forms are filled and submitted electronically on TRC website. Each of the proposals submitted to TRC is selected through a rigorous reviewing and screening process. Novelty and originality of the research idea is the most crucial element in writing a research proposal. Performing an in-depth review of the literature will assist you to compose a good researchable question and generate a strong hypothesis. The development of a good hypothesis will offer insight into the specific objectives of a study. Research objectives should be focused, measurable, and achievable by a specific time using the most appropriate methodology. Moreover, it is essential to select a proper study design in-line with the purpose of the study and the hypothesis. Furthermore, social/economic impact and reasonable budget of proposed research are important criteria in research proposal evaluation by TRC. Finally, ethical principles should be observed before writing a research proposal involving human or animal subjects.

  5. Mental illness research in the Gulf Cooperation Council: a scoping review.

    Science.gov (United States)

    Hickey, Jason E; Pryjmachuk, Steven; Waterman, Heather

    2016-08-04

    Rapid growth and development in recent decades has seen mental health and mental illness emerge as priority health concerns for the Gulf Cooperation Council (Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates). As a result, mental health services in the region are being redefined and expanded. However, there is a paucity of local research to guide ongoing service development. Local research is important because service users' experience of mental illness and mental health services are linked to their sociocultural context. In order for service development to be most effective, there is a need for increased understanding of the people who use these services.This article aims to review and synthesize mental health research from the Gulf Cooperation Council. It also seeks to identify gaps in the literature and suggest directions for future research. A scoping framework was used to conduct this review. To identify studies, database searches were undertaken, regional journals were hand-searched, and reference lists of included articles were examined. Empirical studies undertaken in the Gulf Cooperation Council that reported mental health service users' experience of mental illness were included. Framework analysis was used to synthesize results. Fifty-five studies met inclusion criteria and the following themes were identified: service preferences, illness (symptomology, perceived cause, impact), and recovery (traditional healing, family support, religion). Gaps included contradictory findings related to the supportive role of the Arabic extended family and religion, under-representation of women in study samples, and limited attention on illness management outside of the hospital setting.From this review, it is clear that the sociocultural context in the region is linked to service users' experience of mental illness. Future research that aims to fill the identified gaps and develop and test culturally appropriate interventions will aid practice

  6. The National Research Council study: "Making sense of ballistic missile defense"

    Science.gov (United States)

    Wilkening, Dean A.

    2014-05-01

    This chapter explains and summarizes the main findings of a recent National Research Council study entitled Making Sense of Ballistic Missile Defense: An Assessment of Concepts and Systems for U.S. Boost-Phase Missile Defense in Comparison to Other Alternatives.

  7. Disposition of recommendations of the National Research Council in the report ''Revitalizing Nuclear Safety Research''

    International Nuclear Information System (INIS)

    1988-06-01

    On December 8, 1986, the Committee on Nuclear Safety Research of the National Research Council submitted its report, ''Revitalizing Nuclear Safety Research,'' to the US Nuclear Regulatory Commission (NRC). The Commission and its staff have carefully reviewed the Committee's report and have extensively examined the planning, implementation, and management of NRC research programs in order to respond most effectively to the Committee's recommendations. This report presents the Commission's view of the Committee's report and describes the actions that are under way in response to its recommendations

  8. Section 4: National Research Council

    International Nuclear Information System (INIS)

    Arseneau, R.; Zelle, J.

    1991-01-01

    A study was carried out to produce a compendium of electric and magnetic field levels in various environments throughout Canada. The contribution of the National Research Council of Canada in cooperation with Ottawa Hydro was to study the magnetic field environment of 29 sites in the Ottawa area, including private residences, place of employment, distribution and transmission lines, and close to padmount transformers. At most sites the electric fields were too low to be measured. Magnetic fields near padmount transformers can be larger than 300 mG, however this rapidly decreases and at 3 feet from the transformers is below 20 mG. Magnetic fields of unbalanced distribution lines can be larger than the fields of balanced lines. The magnetic fields of a high voltage transmission line were measurable at distances up to 100 m from the line. Electric fields were low outside the right-of-way. 6 refs., 4 figs., 2 tabs

  9. National Safety Council

    Science.gov (United States)

    ... work, in homes and communities, and on the road through leadership, research, education and advocacy. NSC Newsletter Sign up for our newsletter! Like Us on Facebook National Safety Council © National Safety Council. All rights reserved. Contact ...

  10. The Geotechnical Board National Research Council. [Annual] activities report, March 1, 1991--June 30, 1992

    Energy Technology Data Exchange (ETDEWEB)

    Smeallie, P.H.

    1993-08-11

    This report covers the activities of the Geotechnical Board and its two national committees, the US National Committee for Rock Mechanics (USNC/RM) and the US National Committee on Tunneling Technology (USNC/TT), for the period from March 1, 1991 to June 30, 1992. The report covers a 16-month period, through June of this year, to bring the reporting period in line with the National Research Council`s (NRC) fiscal year. Subsequent reports will cover the 12-month period July 1--June 30, unless individual contracts require otherwise. A description of the Geotechnical Board and its committees within the context of the National Academy of Sciences/National Research Council, as well as lists of current members of the board and national committees can be found in Attachment A.

  11. Open Letter to Research Councils UK: Rebuttal of ALPSP Critique

    OpenAIRE

    Berners-Lee, Tim; De Roure, Dave; Harnad, Stevan; Shadbolt, Nigel

    2005-01-01

    The Research Councils of the UK (RCUK) propose to require that the authors of all journal articles resulting from RCUK-funded research must make them openly accessible by self-archiving them on the web in order maximise their usage and impact. ALPSP (Association of Learned and Professional Society Publishers) claim that this will have a negative effect on journals, but the only evidence they provide fails to support their claim and all existing evidence is to the contrary: Journal publication...

  12. Introduction to Medical Research Council Delivery Plan during 2009 to 2014

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    @@ Introduction The Medical Research Foundation is the Medical Research Council's (MRC) independently managed charity.It receives funds from the giving public to support medical research, training, public engagement and dissemination of knowledge.Since it was first established in 1920, the MRC has been able to accept charitable bequests, endowments and donations from the public to contribute towards the costs of the research that it undertakes.The MRC registered these charitable funds with the Charity Commission in the late 1960's and its charity - the Medical Research Foundation-has been successfully supporting medical research for over 80 years.

  13. Digital Games and the US National Research Council's Science Proficiency Goals

    Science.gov (United States)

    Martinez-Garza, Mario; Clark, Douglas B.; Nelson, Brian C.

    2013-01-01

    This review synthesises research on digital games and science learning as it supports the goals for science proficiency outlined in the report by the US National Research Council on science education reform. The review is organised in terms of these research-based goals for science proficiency in light of their alignment with current science…

  14. A National Research Agenda for Virtual Reality: Report by the National Research Council Committee on VR R&D

    OpenAIRE

    Pausch, Randy; Aviles, Walter; Durlach, Nathaniel; Robinett, Warren; Zyda, Michael

    1995-01-01

    In 1992, at the request of a consortium of federal agencies, the National Research Council established a committee to "recommand a national research and development agenda in the area of virtual reality" to set U.S. government R&D funding priorities for virtual reality (VR) for the next decade....

  15. 75 FR 57520 - NASA Advisory Council; Planetary Science Subcommittee; Supporting Research and Technology Working...

    Science.gov (United States)

    2010-09-21

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (10-112)] NASA Advisory Council; Planetary Science Subcommittee; Supporting Research and Technology Working Group; Meeting AGENCY: National... announces a meeting of the Supporting Research and Technology Working Group of the Planetary Science...

  16. Report of the Science and Engineering Research Council for the year 1987-88

    International Nuclear Information System (INIS)

    1988-12-01

    The paper presents the Annual Report of the Science and Engineering Research Council (SERC), United Kingdom 1987/8. The contents contains the reports of the four Boards of the Council - the Astronomy and Planetary Science Board, the Engineering Board, the Nuclear Physics Board and the Science Board. The SERC report also contains eleven review articles on major advances in Science in recent years, including high temperature superconductivity and the supernova in the Large Magellanic Cloud, as well as details of fourteen ''highlights'' of 1987/8 including the dating of the Turin Shroud. (U.K.)

  17. New roles and strategies of a research council: intermediation of the principal-agent relationship

    NARCIS (Netherlands)

    van der Meulen, Barend

    2003-01-01

    Research councils have mediated the principal-agent relation between government and science: they are expected to mediate the political and policy interests in scientific research into the world of science and technology and promote the interests of science and technology in the policy world.

  18. The Medical Research Council (UK)/Uganda Virus Research Institute Uganda Research Unit on AIDS--'25 years of research through partnerships'.

    Science.gov (United States)

    Kaleebu, P; Kamali, A; Seeley, J; Elliott, A M; Katongole-Mbidde, E

    2015-02-01

    For the past 25 years, the Medical Research Council/Uganda Virus Research Institute Uganda Research Unit on AIDS has conducted research on HIV-1, coinfections and, more recently, on non-communicable diseases. Working with various partners, the research findings of the Unit have contributed to the understanding and control of the HIV epidemic both in Uganda and globally, and informed the future development of biomedical HIV interventions, health policy and practice. In this report, as we celebrate our silver jubilee, we describe some of these achievements and the Unit's multidisciplinary approach to research. We also discuss the future direction of the Unit; an exemplar of a partnership that has been largely funded from the north but led in the south. © 2014 The Authors. Tropical Medicine & International Health Published by John Wiley & Sons Ltd.

  19. The impact of CFD on development test facilities - A National Research Council projection. [computational fluid dynamics

    Science.gov (United States)

    Korkegi, R. H.

    1983-01-01

    The results of a National Research Council study on the effect that advances in computational fluid dynamics (CFD) will have on conventional aeronautical ground testing are reported. Current CFD capabilities include the depiction of linearized inviscid flows and a boundary layer, initial use of Euler coordinates using supercomputers to automatically generate a grid, research and development on Reynolds-averaged Navier-Stokes (N-S) equations, and preliminary research on solutions to the full N-S equations. Improvements in the range of CFD usage is dependent on the development of more powerful supercomputers, exceeding even the projected abilities of the NASA Numerical Aerodynamic Simulator (1 BFLOP/sec). Full representation of the Re-averaged N-S equations will require over one million grid points, a computing level predicted to be available in 15 yr. Present capabilities allow identification of data anomalies, confirmation of data accuracy, and adequateness of model design in wind tunnel trials. Account can be taken of the wall effects and the Re in any flight regime during simulation. CFD can actually be more accurate than instrumented tests, since all points in a flow can be modeled with CFD, while they cannot all be monitored with instrumentation in a wind tunnel.

  20. Gender equality observations and actions by the European Research Council

    Science.gov (United States)

    Rydin, Claudia Alves de Jesus; Farina Busto, Luis; Penny, Martin

    2016-04-01

    Women have historically been underrepresented in science. Much positive progress in attracting women to research careers has been achieved in recent years; however, the most influential and high profile positions in most countries are still predominantly occupied by men. The European Research Council (ERC), Europe's premiere funding agency for frontier research, views gender equality as an important challenge. The ERC monitors closely gender figures on every call and has taken actions to tackle gender imbalances and potential unconscious biases. The ERC talk is focused on efforts made to understand and ensure equal treatment of all candidates, with particular focus on gender balance and with specific attention to geosciences. Data and statistics collected from ERC's internationally recognised funding schemes are presented.

  1. Research Areas - Clinical Trials

    Science.gov (United States)

    Information about NCI programs and initiatives that sponsor, conduct, develop, or support clinical trials, including NCI’s Clinical Trial Network (NCTN) and NCI Community Oncology Research Program (NCORP) initiatives.

  2. Review of the National Research Council report: Physics through the 1990's

    International Nuclear Information System (INIS)

    1987-02-01

    The report of the National Research Council (NRC), Physics through the 1990s, highlights past developments and research opportunities in the various subfields of physics and addresses general issues concerning the present state of the discipline in the United States. At the request of the Secretary of Energy, the Energy Research Advisory Board (ERAB) reviewed this report and identified the areas that relate to the programs and objectives of the Department of Energy (DOE). The present report provides the conclusions of this review and the recommendations for the Department's actions

  3. National Research Council Research Associateships Program with Methane Hydrates Fellowships Program/National Energy Technology Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Basques, Eric O. [National Academy of Sciences, Washington, DC (United States)

    2014-03-20

    This report summarizes work carried out over the period from July 5, 2005-January 31, 2014. The work was carried out by the National Research Council Research Associateships Program of the National Academies, under the US Department of Energy's National Energy Technology Laboratory (NETL) program. This Technical Report consists of a description of activity from 2005 through 2014, broken out within yearly timeframes, for NRC/NETL Associateships researchers at NETL laboratories which includes individual tenure reports from Associates over this time period. The report also includes individual tenure reports from associates over this time period. The report also includes descriptions of program promotion efforts, a breakdown of the review competitions, awards offered, and Associate's activities during their tenure.

  4. Inconsistencies in quality of life data collection in clinical trials: a potential source of bias? Interviews with research nurses and trialists.

    Science.gov (United States)

    Kyte, Derek; Ives, Jonathan; Draper, Heather; Keeley, Thomas; Calvert, Melanie

    2013-01-01

    Patient-reported outcomes (PROs), such as health-related quality of life (HRQL) are increasingly used to evaluate treatment effectiveness in clinical trials, are valued by patients, and may inform important decisions in the clinical setting. It is of concern, therefore, that preliminary evidence, gained from group discussions at UK-wide Medical Research Council (MRC) quality of life training days, suggests there are inconsistent standards of HRQL data collection in trials and appropriate training and education is often lacking. Our objective was to investigate these reports, to determine if they represented isolated experiences, or were indicative of a potentially wider problem. We undertook a qualitative study, conducting 26 semi-structured interviews with research nurses, data managers, trial coordinators and research facilitators involved in the collection and entry of HRQL data in clinical trials, across one primary care NHS trust, two secondary care NHS trusts and two clinical trials units in the UK. We used conventional content analysis to analyze and interpret our data. Our study participants reported (1) inconsistent standards in HRQL measurement, both between, and within, trials, which appeared to risk the introduction of bias; (2), difficulties in dealing with HRQL data that raised concern for the well-being of the trial participant, which in some instances led to the delivery of non-protocol driven co-interventions, (3), a frequent lack of HRQL protocol content and appropriate training and education of trial staff, and (4) that HRQL data collection could be associated with emotional and/or ethical burden. Our findings suggest there are inconsistencies in the standards of HRQL data collection in some trials resulting from a general lack of HRQL-specific protocol content, training and education. These inconsistencies could lead to biased HRQL trial results. Future research should aim to develop HRQL guidelines and training programmes aimed at supporting

  5. 7 CFR 1230.6 - Council.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Council. 1230.6 Section 1230.6 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION Pork Promotion, Research, and Consumer Information Order Definitions § 1230.6 Council...

  6. Report of The Science and Engineering Research Council for the year 1989-90

    International Nuclear Information System (INIS)

    1990-01-01

    This twenty-fifth anniversary issue of the Science and Engineering Research Council's (SERC) Annual Report opens by reemphasizing the continuing need to plan research expenditure on a greater than annual basis. Exciting developments in every branch and discipline continue to emerge. This year has seen advances in public relations for SERC with the plans for a science centre on the Royal Observatory, Edinburgh site, and a national essay competition for school children. (UK)

  7. 7α-methyl-19-nortestosterone (MENTR): the population council's contribution to research on male contraception and treatment of hypogonadism.

    Science.gov (United States)

    Nieschlag, Eberhard; Kumar, Narender; Sitruk-Ware, Régine

    2013-03-01

    Testosterone is an essential part of all regimens for hormonal male contraception tested to date. Initial efficacy trials revealed that the half-life of the testosterone preparations available at that time was too short to be used for male contraception. The ensuing search for long-acting preparations yielded testosterone buciclate and undecanoate as well as 7α-methyl-19-nortestosterone (MENT). Following description of the principle of male hormonal contraception and the efficacy trials performed to date, the systematic development of MENT for substitution of male hypogonadism and use in male contraception by the Population Council is reviewed here. Copyright © 2013. Published by Elsevier Inc.

  8. Science Granting Councils Initiative: Research uptake | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The Science Granting Councils Initiative in sub-Saharan Africa aims to ... The strategy identifies a wide range of activities to collect, package, and share lessons ... Organization for Women in Science for the Developing World (OWSD), IDRC is ...

  9. EPRI/Alberta Research Council Clean Soil Process

    International Nuclear Information System (INIS)

    Spear, C.E.

    1992-12-01

    The EPRI/Alberta Research Council Clean Soil Process can remove hydrocarbon contamination from waste material from manufactured gas plants. The process uses coal as an absorbent to remove hydrocarbons. For petroleum contaminated soils, the process can bring residual concentration of petroleum below 0.1 percent and polycyclic aromatic hydrocarbon (PAH) concentration to 1--5 ppM. For coal tar contaminated soils, the process can reduce tar concentrations to about 0.05-0.5 percent and the PAH concentration to about 10--60 ppM. Additional post-treatment may be required for some precleaned soils. The process yields by-product agglomerates suitable for combustion in industrial boilers. Light hydrocarbons such as benzene are vaporized from the soil, condensed and collected in the Process and disposed of off-site. The Clean Soil Process has been tested at pilot-plant scale. A conceptual design for a 200-tons-per-day plant yielded a capital cost estimated at $3.1 million with a per-ton operating cost of $40

  10. Cohort Profile : The National Academy of Sciences-National Research Council Twin Registry (NAS-NRC Twin Registry)

    NARCIS (Netherlands)

    Gatz, Margaret; Harris, Jennifer R.; Kaprio, Jaakko; McGue, Matt; Smith, Nicholas L.; Snieder, Harold; Spiro, Avron; Butler, David A.

    The National Academy of Sciences-National Research Council Twin Registry (NAS-NRC Twin Registry) is a comprehensive registry of White male twin pairs born in the USA between 1917 and 1927, both of the twins having served in the military. The purpose was medical research and ultimately improved

  11. Late Gastrointestinal Toxicity After Dose-Escalated Conformal Radiotherapy for Early Prostate Cancer: Results From the UK Medical Research Council RT01 Trial (ISRCTN47772397)

    International Nuclear Information System (INIS)

    Syndikus, Isabel; Morgan, Rachel C.; Sydes, Matthew R.; Graham, John D.; Dearnaley, David P.

    2010-01-01

    Purpose: In men with localized prostate cancer, dose-escalated conformal radiotherapy (CFRT) improves efficacy outcomes at the cost of increased toxicity. We present a detailed analysis to provide further information about the incidence and prevalence of late gastrointestinal side effects. Methods and Materials: The UK Medical Research Council RT01 trial included 843 men with localized prostate cancer, who were treated for 6 months with neoadjuvant radiotherapy and were randomly assigned to either 64-Gy or 74-Gy CFRT. Toxicity was evaluated before CFRT and during long-term follow-up using Radiation Therapy Oncology Group (RTOG) grading, the Late Effects on Normal Tissue: Subjective, Objective, Management (LENT/SOM) scale, and Royal Marsden Hospital assessment scores. Patients regularly completed Functional Assessment of Cancer Therapy--Prostate (FACT-P) and University of California, Los Angeles, Prostate Cancer Index (UCLA-PCI) questionnaires. Results: In the dose-escalated group, the hazard ratio (HR) for rectal bleeding (LENT/SOM grade ≥2) was 1.55 (95% CI, 1.17-2.04); for diarrhea (LENT/SOM grade ≥2), the HR was 1.79 (95% CI, 1.10-2.94); and for proctitis (RTOG grade ≥2), the HR was 1.64 (95% CI, 1.20-2.25). Compared to baseline scores, the prevalence of moderate and severe toxicities generally increased up to 3 years and than lessened. At 5 years, the cumulative incidence of patient-reported severe bowel problems was 6% vs. 8% (standard vs. escalated, respectively) and severe distress was 4% vs. 5%, respectively. Conclusions: There is a statistically significant increased risk of various adverse gastrointestinal events with dose-escalated CFRT. This remains at clinically acceptable levels, and overall prevalence ultimately decreases with duration of follow-up.

  12. Theory of Change: a theory-driven approach to enhance the Medical Research Council's framework for complex interventions.

    Science.gov (United States)

    De Silva, Mary J; Breuer, Erica; Lee, Lucy; Asher, Laura; Chowdhary, Neerja; Lund, Crick; Patel, Vikram

    2014-07-05

    The Medical Research Councils' framework for complex interventions has been criticized for not including theory-driven approaches to evaluation. Although the framework does include broad guidance on the use of theory, it contains little practical guidance for implementers and there have been calls to develop a more comprehensive approach. A prospective, theory-driven process of intervention design and evaluation is required to develop complex healthcare interventions which are more likely to be effective, sustainable and scalable. We propose a theory-driven approach to the design and evaluation of complex interventions by adapting and integrating a programmatic design and evaluation tool, Theory of Change (ToC), into the MRC framework for complex interventions. We provide a guide to what ToC is, how to construct one, and how to integrate its use into research projects seeking to design, implement and evaluate complex interventions using the MRC framework. We test this approach by using ToC within two randomized controlled trials and one non-randomized evaluation of complex interventions. Our application of ToC in three research projects has shown that ToC can strengthen key stages of the MRC framework. It can aid the development of interventions by providing a framework for enhanced stakeholder engagement and by explicitly designing an intervention that is embedded in the local context. For the feasibility and piloting stage, ToC enables the systematic identification of knowledge gaps to generate research questions that strengthen intervention design. ToC may improve the evaluation of interventions by providing a comprehensive set of indicators to evaluate all stages of the causal pathway through which an intervention achieves impact, combining evaluations of intervention effectiveness with detailed process evaluations into one theoretical framework. Incorporating a ToC approach into the MRC framework holds promise for improving the design and evaluation of complex

  13. Research use and support needs, and research activity in social care: a cross-sectional survey in two councils with social services responsibilities in the UK.

    Science.gov (United States)

    Cooke, Jo; Bacigalupo, Ruth; Halladay, Linsay; Norwood, Hayley

    2008-09-01

    The purpose of this study was to investigate the level of research activity, research use, research interests and research skills in the social care workforce in two UK councils with social service responsibilities (CSSRs). A cross-sectional survey was conducted of the social care workforce in two CSSRs (n = 1512) in 2005. The sample was identified in partnership with the councils, and included employees with professional qualifications (social workers and occupational therapists); staff who have a role to assess, plan and monitor care; service managers; commissioners of services; and those involved with social care policy, information management and training. The survey achieved a response rate of 24% (n = 368). The Internet was reported as an effective source of research information; conversely, research-based guidelines were reported to have a low impact on practice. Significant differences were found in research use, by work location, and postgraduate training. Most respondents saw research as useful for practice (69%), and wanted to collaborate in research (68%), but only 11% were planning to do research within the next 12 months. Having a master's degree was associated with a greater desire to lead or collaborate in research. A range of research training needs, and the preferred modes of delivery were identified. Support to increase research activity includes protected time and mentorship. The study concludes that a range of mechanisms to make research available for the social care workforce needs to be in place to support evidence-informed practice. Continual professional development to a postgraduate level supports the use and production of evidence in the social care workforce, and promotes the development of a research culture. The term research is used to include service user consultations, needs assessment and service evaluation. The findings highlight a relatively large body of the social care workforce willing to collaborate and conduct research

  14. Council Chamber exhibition

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    To complete the revamp of CERN’s Council Chamber, a new exhibition is being installed just in time for the June Council meetings.   Panels will showcase highlights of CERN’s history, using some of the content prepared for the exhibitions marking 50 years of the PS, which were displayed in the main building last November. The previous photo exhibition in the Council Chamber stopped at the 1970s. To avoid the new panels becoming quickly out of date, photos are grouped together around specific infrastructures, rather than following a classic time-line. “We have put the focus on the accelerators – the world-class facilities that CERN has been offering researchers over the years, from the well-known large colliders to the lesser-known smaller facilities,” says Emma Sanders, who worked on the content. The new exhibition will be featured in a future issue of the Bulletin with photos and an interview with Fabienne Marcastel, designer of the exhibit...

  15. Alberta Research Council 1999 annual report: innovation for a new millennium

    International Nuclear Information System (INIS)

    1999-01-01

    The Alberta Research Council (ARC) develops and commercializes technologies to give its clients a competitive advantage. It carries out applied R and D on a contract or fee basis, and co-ventures with others to develop new technologies, deriving a return on investment from the commercialization of new products and services. ARC carries out research in the following sectors: 1) agriculture and biotechnology; 2) energy: conventional and heavy oil recovery and production technologies, reservoir management processes and protocols, novel downhole oilfield equipment, speciality sensors and instrumentation, and upgrading technologies for improved recovery and cost efficiency; and as well industrial processes and technologies related to water and land management and climate change to ensure sustainable development; 3) forestry; 4) environment: research to comprehend and mitigate the impact of industrial activities on air, water and land resources, including climate change, greenhouse gases and carbon dioxide management strategies; clean process and waste minimization technologies; and advanced environmental analyses and toxicology

  16. A Very Early Rehabilitation Trial after stroke (AVERT): a Phase III, multicentre, randomised controlled trial.

    Science.gov (United States)

    Langhorne, Peter; Wu, Olivia; Rodgers, Helen; Ashburn, Ann; Bernhardt, Julie

    2017-09-01

    outcome at 3 months cautioning against very early high-dose mobilisation. At 12 months, health-related QoL was similar regardless of group. Shorter, more frequent mobilisation early after stroke may be associated with a more favourable outcome. These results informed a new trial proposal [A Very Early Rehabilitation Trial - DOSE (AVERT-DOSE)] aiming to determine the optimal frequency and dose of EM. The trial is registered with the Australian New Zealand Clinical Trials Registry number ACTRN12606000185561, Current Controlled Trials ISRCTN98129255 and ISRCTN98129255. This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment ; Vol. 21, No. 54. See the NIHR Journals Library website for further project information. Funding was also received from the National Health and Medical Research Council Australia, Singapore Health, Chest Heart and Stroke Scotland, Northern Ireland Chest Heart and Stroke, and the Stroke Association. In addition, National Health and Medical Research Council fellowship funding was provided to Julie Bernhardt (1058635), who also received fellowship funding from the Australia Research Council (0991086) and the National Heart Foundation (G04M1571). The Florey Institute of Neuroscience and Mental Health, which hosted the trial, acknowledges the support received from the Victorian Government via the Operational Infrastructure Support Scheme.

  17. Advances in cardiovascular research. 15th Annual Meeting of the European Council for Cardiovascular Research (ECCR). La Colle sur Loup, France, 8–10 October 2010

    NARCIS (Netherlands)

    Steckelings, U. Muscha; de Mey, Jo G. R.; Pinto-Sietsma, Sara-Joan; Henrion, Daniel; Unger, Thomas

    2011-01-01

    The 15th Annual Meeting of the European Council of Cardiovascular Research brought together basic and clinical scientists working in the cardiovascular field in La Colle sur Loup, France. Upfront basic and clinical research addressing the mechanisms of disease, identification of biomarkers or

  18. Qualitative research within trials: developing a standard operating procedure for a clinical trials unit

    Science.gov (United States)

    2013-01-01

    Background Qualitative research methods are increasingly used within clinical trials to address broader research questions than can be addressed by quantitative methods alone. These methods enable health professionals, service users, and other stakeholders to contribute their views and experiences to evaluation of healthcare treatments, interventions, or policies, and influence the design of trials. Qualitative data often contribute information that is better able to reform policy or influence design. Methods Health services researchers, including trialists, clinicians, and qualitative researchers, worked collaboratively to develop a comprehensive portfolio of standard operating procedures (SOPs) for the West Wales Organisation for Rigorous Trials in Health (WWORTH), a clinical trials unit (CTU) at Swansea University, which has recently achieved registration with the UK Clinical Research Collaboration (UKCRC). Although the UKCRC requires a total of 25 SOPs from registered CTUs, WWORTH chose to add an additional qualitative-methods SOP (QM-SOP). Results The qualitative methods SOP (QM-SOP) defines good practice in designing and implementing qualitative components of trials, while allowing flexibility of approach and method. Its basic principles are that: qualitative researchers should be contributors from the start of trials with qualitative potential; the qualitative component should have clear aims; and the main study publication should report on the qualitative component. Conclusions We recommend that CTUs consider developing a QM-SOP to enhance the conduct of quantitative trials by adding qualitative data and analysis. We judge that this improves the value of quantitative trials, and contributes to the future development of multi-method trials. PMID:23433341

  19. 75 FR 52719 - South Atlantic Fishery Management Council; Public Meetings

    Science.gov (United States)

    2010-08-27

    ... will receive a report on outreach and research activities associated with the Oculina Bank Experimental...-Based Management Committee will receive an overview of the actions and alternatives currently in draft... documents, review the Council's research plan, develop recommendations relative to Council stock assessment...

  20. Design of the Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial

    OpenAIRE

    Bradford, A.; Lees, K.

    2000-01-01

    The Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial is a multicentre,randomised, placebo-controlled trial of magnesium sulphate (MgSO4) funded by the UK Medical Research Council. When complete, it will be the largest single neuroprotective study undertaken to date. Conscious patients presenting within 12 h of acute stroke with limb weakness are eligible. The primary outcome measure is combined death and disability as measured using the Barthel Index at 90-day follow up. By rando...

  1. Guidance for Researchers Developing and Conducting Clinical Trials in Practice-based Research Networks (PBRNs)

    Science.gov (United States)

    Dolor, Rowena J.; Schmit, Kristine M.; Graham, Deborah G.; Fox, Chester H.; Baldwin, Laura Mae

    2015-01-01

    Background There is increased interest nationally in multicenter clinical trials to answer questions about clinical effectiveness, comparative effectiveness, and safety in real-world community settings. Primary care practice-based research networks (PBRNs), comprising community- and/or academically affiliated practices committed to improving medical care for a range of health problems, offer ideal settings for these trials, especially pragmatic clinical trials. However, many researchers are not familiar with working with PBRNs. Methods Experts in practice-based research identified solutions to challenges that researchers and PBRN personnel experience when collaborating on clinical trials in PBRNs. These were organized as frequently asked questions in a draft document presented at a 2013 Agency for Health care Research and Quality PBRN conference workshop, revised based on participant feedback, then shared with additional experts from the DARTNet Institute, Clinical Translational Science Award PBRN, and North American Primary Care Research Group PBRN workgroups for further input and modification. Results The “Toolkit for Developing and Conducting Multi-site Clinical Trials in Practice-Based Research Networks” offers guidance in the areas of recruiting and engaging practices, budgeting, project management, and communication, as well as templates and examples of tools important in developing and conducting clinical trials. Conclusion Ensuring the successful development and conduct of clinical trials in PBRNs requires a highly collaborative approach between academic research and PBRN teams. PMID:25381071

  2. National research council report and its impact on nuclear engineering education at the University of Michigan

    International Nuclear Information System (INIS)

    Martin, W.R.

    1991-01-01

    A recent report by the National Research Council raised a number of important issues that will have an impact on nuclear engineering departments across the country. The report has been reviewed in the context of its relevance to the Department of Nuclear Engineering at the University of Michigan (UM), and some observations and conclusions have been drawn. This paper focuses on those portions of Ref. 1 concerning undergraduate and graduate curricula, research facilities and laboratories, faculty research interests, and funding for research and graduate student support because these topics have a direct impact on current and future directions for the department

  3. Council dinner

    CERN Multimedia

    1980-01-01

    Jean Teillac (President of the Council) gives the speech. The occasion was the end-of-term of Leon Van Hove and John Adams as Research and Executive Director-General, respectively, to be succeeded by Herwig Schopper. The venue was the Hotel Beau-Rivage in Geneva. Beside Jean Teillac are (on the left) G.H. Stafford and Mme Van Hove, (on the right) Mme Schopper.

  4. Observations and actions to ensure equal treatment of all candidates by the European Research Council

    Science.gov (United States)

    Rydin, Claudia Alves de Jesus; Farina Busto, Luis; El Mjiyad, Nadia; Kota, Jhansi; Thelen, Lionel

    2017-04-01

    The European Research Council (ERC), Europe's premiere funding agency for frontier research, views equality of opportunities as an important challenge. The ERC monitors closely gender figures on every call and has taken actions to tackle imbalances and potential unconscious biases. The ERC talk is focused on efforts made to understand and ensure equal treatment of all candidates, with particular focus on gender balance and with specific attention to geosciences. Data and statistics collected in running highly competitive and internationally recognised funding schemes are presented. Recent initiatives to tackle geographical imbalances will also be presented.

  5. Ocean Science for Decision-Making: Current Activities of the National Research Council's Ocean Studies Board

    Science.gov (United States)

    Roberts, S.; Glickson, D.; Mengelt, C.; Forrest, S.; Waddell, K.

    2012-12-01

    The National Research Council is a private, nonprofit organization chartered by Congress in 1916 as an expansion of the U.S. National Academy of Sciences. Its mission is to improve the use of science in government decision making and public policy, increase public understanding, and promote the acquisition and dissemination of knowledge in matters involving science, engineering, technology, and health. Within the National Research Council, the Ocean Studies Board (OSB) mission is to explore the science, policies, and infrastructure needed to understand, manage, and conserve coastal and marine environments and resources. OSB undertakes studies and workshops on emerging scientific and policy issues at the request of federal agencies, Congress, and others; provides program reviews and guidance; and facilitates communication on oceanographic issues among different sectors. OSB also serves as the U.S. National Committee to the international, nongovernmental Scientific Committee on Oceanic Research (SCOR). OSB has produced reports on a wide range of topics of interest to researchers and educators, the federal government, the non-profit sector, and industry. Recent reports have focused on ecosystem services in the Gulf of Mexico after the Deepwater Horizon oil spill, sea level rise on the U.S. west coast, scientific ocean drilling needs and accomplishments, requirements for sustained ocean color measurements, critical infrastructure for ocean research, tsunami warning and preparedness, ocean acidification, and marine and hydrokinetic power resource assessments. Studies that are currently underway include responding to oil spills in the Arctic, evaluating the effectiveness of fishery stock rebuilding plans, and reviewing the National Ocean Acidification Research Plan. OSB plays an important role in helping create policy decisions and disseminating important information regarding various aspects of ocean science.

  6. NIH Clinical Research Trials and You

    Science.gov (United States)

    ... Info Lines Health Services Locator HealthCare.gov NIH Clinical Research Trials and You Talking to Your Doctor Science ... Labs & Clinics Training Opportunities Library Resources Research Resources Clinical Research Resources Safety, Regulation and Guidance More » Quick Links ...

  7. News from Council - September 2016

    CERN Multimedia

    2016-01-01

    I would like to inform you of the main news from the Council this week. First of all, the Council congratulated CERN and the Collaborations on the superb performance of the accelerator complex and experiments. It has been a great year so far, with important physics results across the whole spectrum of the CERN research programme.   Looking forward, one of the main accomplishments from this week’s meetings is that the Council has approved the opening of a credit facility with the European Investment Bank (EIB) to cover the cash shortage during the peak years of the High-Luminosity LHC (HL-LHC) construction. This is very good news since it will allow us to carry out the work necessary for the HL-LHC without compromising the rest of the Laboratory’s scientific programme. Turning to the scientific and geographical enlargement, the Council approved the admission of India as an Associate Member State, and I very much hope that the agreement can be signed in the near future so that Indi...

  8. Exploring the experiences of substitute decision-makers with an exception to consent in a paediatric resuscitation randomised controlled trial: study protocol for a qualitative research study

    Science.gov (United States)

    de Laat, Sonya; Schwartz, Lisa

    2016-01-01

    Introduction Prospective informed consent is required for most research involving human participants; however, this is impracticable under some circumstances. The Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans (TCPS) outlines the requirements for research involving human participants in Canada. The need for an exception to consent (deferred consent) is recognised and endorsed in the TCPS for research in individual medical emergencies; however, little is known about substitute decision-maker (SDM) experiences. A paediatric resuscitation trial (SQUEEZE) (NCT01973907) using an exception to consent process began enrolling at McMaster Children's Hospital in January 2014. This qualitative research study aims to generate new knowledge on SDM experiences with the exception to consent process as implemented in a randomised controlled trial. Methods and analysis The SDMs of children enrolled into the SQUEEZE pilot trial will be the sampling frame from which ethics study participants will be derived. Design: Qualitative research study involving individual interviews and grounded theory methodology. Participants: SDMs for children enrolled into the SQUEEZE pilot trial. Sample size: Up to 25 SDMs. Qualitative methodology: SDMs will be invited to participate in the qualitative ethics study. Interviews with consenting SDMs will be conducted in person or by telephone, taped and professionally transcribed. Participants will be encouraged to elaborate on their experience of being asked to consent after the fact and how this process occurred. Analysis: Data gathering and analysis will be undertaken simultaneously. The investigators will collaborate in developing the coding scheme, and data will be coded using NVivo. Emerging themes will be identified. Ethics and dissemination This research represents a rare opportunity to interview parents/guardians of critically ill children enrolled into a resuscitation trial without their knowledge or prior consent

  9. Public information about clinical trials and research.

    Science.gov (United States)

    Plétan, Yannick; Zannad, Faïez; Jaillon, Patrice

    2003-01-01

    Be it to restore the confused image of clinical research in relation to the lay public, or to develop new ways of accruing healthy volunteers or patients for clinical trials, there is a need to draft some guidance on how best to provide information on research. Although the French legal and regulatory armamentarium in this area is essentially liberal, there is currently little-justified reluctance among study sponsors to advertise publicly. A group of academic and pharmaceutical industry researchers, assembled for a workshop, together with regulators, journalists, representatives from ethics committees, social security, patient and health consumer groups and other French institutional bodies, has suggested the following series of recommendations: there is no need for additional legal or regulatory constraints; sponsors should be aware of and make use of direct public information on trials; a 'good practice charter' on public communication about clinical trials should be developed; all professionals should be involved in this communication platform; communication in the patient's immediate vicinity should be preferred (primary-care physician, local press); clinical databases and websites accessible to professionals, but also to patients and non-professionals, should be developed; genuine instruction on clinical trials for physicians and health professionals unfamiliar with such trials should be developed and disseminated; media groups should receive at least some training in the fundamentals of clinical research.

  10. Meeting of the ITER Council

    International Nuclear Information System (INIS)

    Drew, M.

    2001-01-01

    Full text: A meeting of the ITER Council took place in Toronto, Canada, on 27-28 February 2001 (Canada participates in the ITER EDA as an associate of the EU Party). The delegations to the Council were led by Dr. U. Finzi, Principal Advisor in charge of Fusion R and D in the Directorate-General for Research of the European Commission, Mr. T. Sugawa, Deputy Director-General of the Research and Development Bureau of the Ministry of Education, Culture, Sport, Science and Technology of Japan, and Academician E. Velikhov, President of the RRC ''Kurchatov Institute''. The European delegation was joined by Canadian experts including a representative from the Canadian Department of Natural Resources. The Council heard presentations from Dr. H. Kishimoto on the successful completion of the Explorations concerning future joint implementation of ITER, and from Dr. J.-P. Rager on the ITER International Industry Liaison Meeting held in Toronto in November 2000. Having noted statements of Parties' status, in particular concerning the readiness to start negotiations and the progress toward site offers, the Council encouraged the Parties to pursue preparations toward future implementation of ITER along the general lines proposed in the Explorers' final report. The Council also noted the readiness the of the RF and EU Parties to instruct specified current JCT members to remain at their places of assignment after the end of the EDA, in preparation for a transition to the Co-ordinated Technical Activities foreseen as support to ITER negotiations. The Council was pleased to hear that meetings with the Director of the ITER Parties' Designated Safety Representatives had started, and commended the progress toward achieving timely licensing processes with a good common understanding. The Council noted with appreciation the Director's view that no difficulties of principle in the licensing approach had been identified during the informal discussions with the regulatory representatives and

  11. Science Granting Councils Initiative in Sub-Saharan Africa ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    This initiative seeks to strengthen the capacities of science granting councils in East Africa and other selected sub-Saharan African countries. The goal is to contribute to economic and social development in the region through research and evidence-based policies. About the science granting councils initiative The Science ...

  12. What Triggers the Establishment of a Works Council?

    OpenAIRE

    Jens Mohrenweiser; Paul Marginson; Uschi Backes-Gellner

    2009-01-01

    This paper analyses events that trigger the establishment of a works council and the actor or agent who triggers it. The paper extends previous research in two dimensions. First, we examine specific events that motivate workers to establish a works council, such as a change of owner, founding a spin-off, a firm-acquisition or a radical restructuring. These events express risk protection as workers’ primary motivation for establishing a works council. Second, we analyse the actor or agent who ...

  13. News from Council

    CERN Multimedia

    2016-01-01

    With this message I would like to share with you some highlights of this week’s Council meetings.   A major topic was the approval of CERN’s Medium Term Plan (MTP) 2017-2021, along with the budget for 2017. In approving the document, Council expressed its very strong support for the research programme the MTP outlines for the coming years.  Another important topic this week was the formal approval of the High Luminosity LHC project, HL-LHC. This comes as extremely good news not only for CERN, but also for particle physics globally. HL-LHC is the top priority of the European Strategy for Particle Physics in its 2013 update, and is part of the 2016 roadmap of the European Strategy Forum on Research Infrastructures, ESFRI. It was also identified as a priority in the US P5 strategy process, and in Japan’s strategic vision for the field. It secures CERN’s future until 2035, and ensures that we will achieve the maximum scientific return on the investment...

  14. Modern Trends in Continuous Professional Development of Foreign Language Teachers (On the Basis of the British Council Research)

    Science.gov (United States)

    Sadovets, Olesia

    2017-01-01

    Research conducted by the British Council concerning modern continuous professional development of teachers has been analyzed. The issue concerning foreign language teachers' professional development has been considered. Productive approach to this process that gives a teacher the opportunities to define aspects of their professional activities…

  15. Networking Africa's science granting councils | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Networking Africa's science granting councils ... to support research and evidence-based policies that contribute to social and economic development. ... exchanges and forums, online training, on-site coaching, and collaborative research.

  16. Design of the Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial [ISRCTN19943732

    OpenAIRE

    Bradford, Andrew; Lees, Kennedy

    2000-01-01

    Abstract The Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial is a multicentre,randomised, placebo-controlled trial of magnesium sulphate (MgSO4) funded by the UK Medical Research Council. When complete, it will be the largest single neuroprotective study undertaken to date. Conscious patients presenting within 12 h of acute stroke with limb weakness are eligible. The primary outcome measure is combined death and disability as measured using the Barthel Index at 90-day follow up....

  17. Clinical trials: bringing research to the bedside.

    Science.gov (United States)

    Arvay, C A

    1991-02-01

    Over the years, clinical trials with their structured treatment plans and multicenter involvement have been instrumental in developing new treatments and establishing standard of care therapy. While clinical trials strive to advance medical knowledge, they provide scientifically sound, state of the art care and their use should be increased. The Brain Tumor Cooperative Group, one such NCI-sponsored cooperative group, has been the primary group for the treatment of malignant gliomas. As the field of neuro-oncology expands, the neuroscience nurse needs to develop an understanding of clinical trials and their operation. The nurse is in an optimal position to support medical research and the research participant.

  18. Councils of Urgent Studies

    Science.gov (United States)

    Cellarius, Richard A.; Platt, John

    1972-01-01

    Discusses the role of national or international coordinating councils in focusing research on solutions of major human problems. Presents a taxonomy of 25 areas under the major heading: Physical Technology and Engineering; Biotechnology; Behavior and Personal Relations; National Social Structures; World Structure; and Channels of Effectiveness.…

  19. Conducting qualitative research within Clinical Trials Units: avoiding potential pitfalls.

    Science.gov (United States)

    Cooper, Cindy; O'Cathain, Alicia; Hind, Danny; Adamson, Joy; Lawton, Julia; Baird, Wendy

    2014-07-01

    The value of using qualitative research within or alongside randomised controlled trials (RCTs) is becoming more widely accepted. Qualitative research may be conducted concurrently with pilot or full RCTs to understand the feasibility and acceptability of the interventions being tested, or to improve trial conduct. Clinical Trials Units (CTUs) in the United Kingdom (UK) manage large numbers of RCTs and, increasingly, manage the qualitative research or collaborate with qualitative researchers external to the CTU. CTUs are beginning to explicitly manage the process, for example, through the use of standard operating procedures for designing and implementing qualitative research with trials. We reviewed the experiences of two UK Clinical Research Collaboration (UKCRC) registered CTUs of conducting qualitative research concurrently with RCTs. Drawing on experiences gained from 15 studies, we identify the potential for the qualitative research to undermine the successful completion or scientific integrity of RCTs. We show that potential problems can arise from feedback of interim or final qualitative findings to members of the trial team or beyond, in particular reporting qualitative findings whilst the trial is on-going. The problems include: We make recommendations for improving the management of qualitative research within CTUs. Copyright © 2014. Published by Elsevier Inc.

  20. Construction of ethics in clinical research: clinical trials registration

    Directory of Open Access Journals (Sweden)

    C. A. Caramori

    2007-01-01

    Full Text Available Scientific development that has been achieved through decades finds in clinical research a great possibility of translating findings to human health application. Evidence given by clinical trials allows everyone to have access to the best health services. However, the millionaire world of pharmaceutical industries has stained clinical research with doubt and improbability. Study results (fruits of controlled clinical trials and scientific publications (selective, manipulated and with wrong conclusions led to an inappropriate clinical practice, favoring the involved economic aspect. In 2005, the International Committee of Medical Journal Editors (ICMJE, supported by the World Association of Medical Editors, started demanding as a requisite for publication that all clinical trials be registered at the database ClinicalTrials.gov. In 2006, the World Health Organization (WHO created the International Clinical Trial Registry Platform (ICTRP, which gathers several registry centers from all over the world, and required that all researchers and pharmaceutical industries register clinical trials. Such obligatory registration has progressed and will extend to all scientific journals indexed in all worldwide databases. Registration of clinical trials means another step of clinical research towards transparency, ethics and impartiality, resulting in real evidence to the forthcoming changes in clinical practice as well as in the health situation.

  1. 76 FR 37064 - Gulf of Mexico Fishery Management Council (Council); Public Meeting

    Science.gov (United States)

    2011-06-24

    ... meeting. SUMMARY: The Gulf of Mexico Fishery Management Council will convene a public meeting via webinar... meeting will be held via webinar. Council address: Gulf of Mexico Fishery Management Council, 2203 North... Executive Director, Gulf of Mexico Fishery Management Council; telephone: (813) 348-1630. SUPPLEMENTARY...

  2. Qualitative research within trials: developing a standard operating procedure for a clinical trials unit

    OpenAIRE

    Rapport, Frances; Clement, Clare

    2013-01-01

    BackgroundQualitative research methods are increasingly used within trials to address broader research questions than quantitative methods can address alone. Qualitative methods enable health professionals, service users and other stakeholders to contribute their views and experiences when evaluating health care treatments, interventions or policies. They can influence trial design, allowing for a fuller engagement with research questions, aims and objectives and clarify the complexities of p...

  3. [Municipal Health Councils: activity and representation of grassroots communities].

    Science.gov (United States)

    Gerschman, Silvia

    2004-01-01

    This article was based on the results of research concerning health policy in municipalities that achieved the most extensive development of decentralization and innovation in the State of Rio de Janeiro, Brazil. The study applied a questionnaire for health system users' representatives in Municipal Health Councils. The central issues were: the Councils' political role; social control by the Councils, viewed as surveillance by organized society over government actions; the nature of social representation exercised by the Council members; and the type of mandate they serve. Community representatives in the Councils reinforce aspects pertaining to the exercise of representation in unequal societies. There is a predominance of a differentiated elite consisting of older males with more schooling and higher income than the community average. The notion of "social control" as the basis for the Councils is difficult for the members to grasp. Exercise of representation is diffuse, occurring by way of designation by community associations, election in assemblies, or designation by institutional health policy agencies.

  4. The Geosciences Division of the Council on Undergraduate Research (GeoCUR): Supporting Faculty that Mentor Undergraduate Researchers

    Science.gov (United States)

    Fox, L. K.; Guertin, L. A.; Manley, P. L.; Fortner, S. K.

    2012-12-01

    Undergraduate research is a proven effective pedagogy that has a number of benefits including: enhancing student learning through mentoring relationships with faculty; increasing retention; increasing enrollment in graduate programs; developing critical thinking, creativity, problem solving and intellectual independence; and, developing an understanding of research methodology. Undergraduate research also has been demonstrated in preparing students for careers. In addition to developing disciplinary and technical expertise, participation in undergraduate research helps students improve communication skills (written, oral, and graphical) and time management. Early involvement in undergraduate research improves retention and, for those engaged at the 2YC level, helps students successfully transfers to 4YC. The Geosciences Division of the Council on Undergraduate Research (GeoCUR) supports faculty in their development of undergraduate research programs at all levels. GeoCUR leads workshops for new and future faculty covering all aspects of undergraduate research including incorporating research into coursework, project design, mentoring students, sustaining programs, and funding sources. GeoCUR members support new faculty by providing a range of services including: peer-review of grant proposals; advice on establishing an undergraduate research program; balancing teaching and research demands; and networking with other geoscientist. GeoCUR has also developed web resources that support faculty and departments in development of undergraduate research programs (http://serc.carleton.edu/NAGTWorkshops/undergraduate_research/index.html). This presentation will describe the services provided by GeoCUR and highlight examples of programs and resources available to geoscientists in all career stages for effective undergraduate research mentoring and development.

  5. News from Council

    CERN Multimedia

    2015-01-01

    Today concludes a very busy week for Council. As you’ll have seen from the press release this morning, Council elected a new President, who will take up his mandate on 1 January along with the new management team, which was also approved by Council yesterday.   You’ll find full details of the incoming Director-General’s management team and structures here. Completing the configuration for the immediate future, Council also approved the medium term plan, along with the budget for 2016. In other Council business, two complete applications for Associate Membership were discussed. Following an earlier letter, India’s complete application was received and considered by Council. Consequently, a fact-finding mission has been established to report back before the end of the year. A new application was also received from Azerbaijan, with a fact-finding mission to be established. India’s involvement with CERN goes back to the 1970s, and the country...

  6. Report of the Science and Engineering Research Council for the year 1986-87

    International Nuclear Information System (INIS)

    1987-01-01

    The report covers the year to March 31 1987. The expenditure of the Council over the year is given. Highlights of the year are summarized -these include laser holography, supercomputers and aerodynamic design, achievements in the Alvey programme, the compact synchrotron X-ray source, observation of the w-boson decay, results form Giotto, fish farming and genetic fingerprinting. Reports of the four boards -astronomy and planetary science, engineering, nuclear physics and science -are presented. Twelve articles then review major advances in recent years. These include the UK at CERN, scanning tunnelling microscopy, recent research using synchrotron x radiation, the European X-ray observatory EXOSAT and global solar oscillations. (U.K.)

  7. Agenda Responsiveness in the European Council

    DEFF Research Database (Denmark)

    Alexandrova, Petya; Rasmussen, Anne; Toshkov, Dimiter

    2016-01-01

    The existence of political responsiveness in multi-level systems like the EU remains an open question despite significant recent research on the topic. This article studies whether the European Council responds to the shifting policy priorities of European citizens. More specifically, it explores......, a detailed examination of the shifts in prioritisation of single issues over time reveals little evidence for dynamic issue responsiveness. Recently the European Council has paid more attention to the issues that the public considered the most pressing problems but the convergence could possibly be driven...

  8. Exploring the experiences of substitute decision-makers with an exception to consent in a paediatric resuscitation randomised controlled trial: study protocol for a qualitative research study.

    Science.gov (United States)

    Parker, Melissa J; de Laat, Sonya; Schwartz, Lisa

    2016-09-13

    Prospective informed consent is required for most research involving human participants; however, this is impracticable under some circumstances. The Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans (TCPS) outlines the requirements for research involving human participants in Canada. The need for an exception to consent (deferred consent) is recognised and endorsed in the TCPS for research in individual medical emergencies; however, little is known about substitute decision-maker (SDM) experiences. A paediatric resuscitation trial (SQUEEZE) (NCT01973907) using an exception to consent process began enrolling at McMaster Children's Hospital in January 2014. This qualitative research study aims to generate new knowledge on SDM experiences with the exception to consent process as implemented in a randomised controlled trial. The SDMs of children enrolled into the SQUEEZE pilot trial will be the sampling frame from which ethics study participants will be derived. Qualitative research study involving individual interviews and grounded theory methodology. SDMs for children enrolled into the SQUEEZE pilot trial. Up to 25 SDMs. Qualitative methodology: SDMs will be invited to participate in the qualitative ethics study. Interviews with consenting SDMs will be conducted in person or by telephone, taped and professionally transcribed. Participants will be encouraged to elaborate on their experience of being asked to consent after the fact and how this process occurred. Data gathering and analysis will be undertaken simultaneously. The investigators will collaborate in developing the coding scheme, and data will be coded using NVivo. Emerging themes will be identified. This research represents a rare opportunity to interview parents/guardians of critically ill children enrolled into a resuscitation trial without their knowledge or prior consent. Findings will inform implementation of the exception to consent process in the planned definitive SQUEEZE

  9. Comparing German and Danish industrial relations actors on European works councils

    DEFF Research Database (Denmark)

    Bicknell, Helen; Knudsen, Herman Lyhne

    The paper brings together recent research carried out by the two authors on German and Danish representatives and representation systems within the context of European Works Councils (EWCs).......The paper brings together recent research carried out by the two authors on German and Danish representatives and representation systems within the context of European Works Councils (EWCs)....

  10. 7 CFR 1209.4 - Council.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Council. 1209.4 Section 1209.4 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION ORDER Mushroom Promotion, Research, and Consumer Information Order Definitions § 1209...

  11. Implementing falls prevention research into policy and practice: an overview of a new National Health and Medical Research Council Partnership Grant.

    Science.gov (United States)

    Lord, Stephen R; Delbaere, Kim; Tiedemann, Anne; Smith, Stuart T; Sturnieks, Daina L

    2011-06-01

    Preventing falls and fall-related injuries among older people is an urgent public health challenge. This paper provides an overview of the background to and research planned for a 5-year National Health and Medical Research Council Partnership Grant on implementing falls prevention research findings into policy and practice. This program represents a partnership between key Australian falls prevention researchers, policy makers and information technology companies which aims to: (1) fill gaps in evidence relating to the prevention of falls in older people, involving new research studies of risk factor assessment and interventions for falls prevention; (2) translate evidence into policy and practice, examining the usefulness of new risk-identification tools in clinical practice; and (3) disseminate evidence to health professionals working with older people, via presentations, new evidence-based guidelines, improved resources and learning tools, to improve the workforce capacity to prevent falls and associated injuries in the future.

  12. Research priorities in Maternal, Newborn, & Child Health & Nutrition for India: An Indian Council of Medical Research-INCLEN Initiative

    Directory of Open Access Journals (Sweden)

    Narendra K Arora

    2017-01-01

    Full Text Available In India, research prioritization in Maternal, Newborn, and Child Health and Nutrition (MNCHN themes has traditionally involved only a handful of experts mostly from major cities. The Indian Council of Medical Research (ICMR-INCLEN collaboration undertook a nationwide exercise engaging faculty from 256 institutions to identify top research priorities in the MNCHN themes for 2016-2025. The Child Health and Nutrition Research Initiative method of priority setting was adapted. The context of the exercise was defined by a National Steering Group (NSG and guided by four Thematic Research Subcommittees. Research ideas were pooled from 498 experts located in different parts of India, iteratively consolidated into research options, scored by 893 experts against five pre-defined criteria (answerability, relevance, equity, investment and innovation and weighed by a larger reference group. Ranked lists of priorities were generated for each of the four themes at national and three subnational (regional levels [Empowered Action Group & North-Eastern States, Southern and Western States, & Northern States (including West Bengal]. Research priorities differed between regions and from overall national priorities. Delivery domain of research which included implementation research constituted about 70 per cent of the top ten research options under all four themes. The results were endorsed in the NSG meeting. There was unanimity that the research priorities should be considered by different governmental and non-governmental agencies for investment with prioritization on implementation research and issues cutting across themes.

  13. Comparison of Indian Council for Medical Research and Lunar Databases for Categorization of Male Bone Mineral Density.

    Science.gov (United States)

    Singh, Surya K; Patel, Vivek H; Gupta, Balram

    2017-06-19

    The mainstay of diagnosis of osteoporosis is dual-energy X-ray absorptiometry (DXA) scan measuring areal bone mineral density (BMD) (g/cm 2 ). The aim of the present study was to compare the Indian Council of Medical Research database (ICMRD) and the Lunar ethnic reference database of DXA scans in the diagnosis of osteoporosis in male patients. In this retrospective study, all male patients who underwent a DXA scan were included. The areal BMD (g/cm 2 ) was measured at either the lumbar spine (L1-L4) or the total hip using the Lunar DXA machine (software version 8.50) manufactured by GE Medical Systems (Shanghai, China). The Indian Council of Medical Research published a reference data for BMD in the Indian population derived from the population-based study conducted in healthy Indian individuals, which was used to analyze the BMD result by Lunar DXA scan. The 2 results were compared for various values using statistical software SPSS for Windows (version 16; SPSS Inc., Chicago, IL). A total 238 male patients with a mean age of 57.2 yr (standard deviation ±15.9) were included. Overall, 26.4% (66/250) and 2.8% (7/250) of the subjects were classified in the osteoporosis group according to the Lunar database and the ICMRD, respectively. Out of the 250 sites of the DXA scan, 28.8% (19/66) and 60.0% (40/66) of the cases classified as osteoporosis by the Lunar database were reclassified as normal and osteopenia by ICMRD, respectively. In conclusion, the Indian Council of Medical Research data underestimated the degree of osteoporosis in male subjects that might result in deferring of treatment. In view of the discrepancy, the decision on the treatment of osteoporosis should be based on the multiple fracture risk factors and less reliably on the BMD T-score. Copyright © 2017 The International Society for Clinical Densitometry. Published by Elsevier Inc. All rights reserved.

  14. List of publications resulting from the Neutron Beam Scattering Programme supported by the Science and Engineering Research Council for 1984

    International Nuclear Information System (INIS)

    1984-12-01

    The paper lists the references of publications resulting from the Neutron Beam Scattering Programme supported by the Science and Engineering Research Council, covering the year 1984, but also including publications from 1983 not given in the previous issue of this listing. (author)

  15. 40 CFR 1508.6 - Council.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Council. 1508.6 Section 1508.6 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY TERMINOLOGY AND INDEX § 1508.6 Council. Council means the Council on Environmental Quality established by title II of the Act. ...

  16. Undergraduate Research as a Process for STEM Teaching and Learning Systemic Change: Lessons Learned from the Council on Undergraduate Research NSF CCLI and TUES Projects

    Science.gov (United States)

    Ambos, E. L.; Havholm, K. G.; Malachowski, M.; Osborn, J.; Karukstis, K.

    2013-12-01

    For more than seven years, the Council on Undergraduate Research (CUR), the primary organization supporting programs, services, and advocacy for undergraduate research, has been working with support from the NSF's Division of Undergraduate Education (DUE) to enhance, sustain, and institutionalize undergraduate research in diverse STEM disciplines and higher education settings. The Council on Undergraduate Research comprises more than 9000 individual and 670 institutional members within a divisional structure that includes geosciences, as well as 11 other thematic areas. Through its most recent grant: 'Transformational Learning through Undergraduate Research: Comprehensive Support for Faculty, Institutions, State Systems and Consortia' (NSF DUE CCLI III Award #09-20275), CUR has been collaborating with six higher education systems, each selected after a rigorous national application process in 2010 and 2011. These six systems, which collectively represent 79 individual institutions, are the Council of Public Liberal Arts Colleges (COPLAC), University of Wisconsin System (UWS), California State University System (CSU), City University of New York (CUNY), Great Lakes Colleges Association (GLCA), and Pennsylvania State System of Higher Education (PASSHE). The more than 350 participants of faculty and senior-level administrators from the six systems are engaged in shared multi-faceted and multi-year professional development experiences. Teams from each system attended customized institutes facilitated by CUR experts in 2011-2012, during which the teams developed specific action plans focused on institutionalizing undergraduate research on their campus and within their system. The systems were reconvened as a group a year after the first institute, to chart progress toward achieving their goals. Based on interviews and surveys with participants, campus teams are making substantial progress toward implementation of robust undergraduate research programs, and are making

  17. What can qualitative research do for randomised controlled trials? A systematic mapping review

    Science.gov (United States)

    O'Cathain, A; Thomas, K J; Drabble, S J; Rudolph, A; Hewison, J

    2013-01-01

    Objective To develop an empirically based framework of the aspects of randomised controlled trials addressed by qualitative research. Design Systematic mapping review of qualitative research undertaken with randomised controlled trials and published in peer-reviewed journals. Data sources MEDLINE, PreMEDLINE, EMBASE, the Cochrane Library, Health Technology Assessment, PsycINFO, CINAHL, British Nursing Index, Social Sciences Citation Index and ASSIA. Eligibility criteria Articles reporting qualitative research undertaken with trials published between 2008 and September 2010; health research, reported in English. Results 296 articles met the inclusion criteria. Articles focused on 22 aspects of the trial within five broad categories. Some articles focused on more than one aspect of the trial, totalling 356 examples. The qualitative research focused on the intervention being trialled (71%, 254/356); the design, process and conduct of the trial (15%, 54/356); the outcomes of the trial (1%, 5/356); the measures used in the trial (3%, 10/356); and the target condition for the trial (9%, 33/356). A minority of the qualitative research was undertaken at the pretrial stage (28%, 82/296). The value of the qualitative research to the trial itself was not always made explicit within the articles. The potential value included optimising the intervention and trial conduct, facilitating interpretation of the trial findings, helping trialists to be sensitive to the human beings involved in trials, and saving money by steering researchers towards interventions more likely to be effective in future trials. Conclusions A large amount of qualitative research undertaken with specific trials has been published, addressing a wide range of aspects of trials, with the potential to improve the endeavour of generating evidence of effectiveness of health interventions. Researchers can increase the impact of this work on trials by undertaking more of it at the pretrial stage and being explicit

  18. Evaluating the design and reporting of pragmatic trials in osteoarthritis research.

    Science.gov (United States)

    Ali, Shabana Amanda; Kloseck, Marita; Lee, Karen; Walsh, Kathleen Ellen; MacDermid, Joy C; Fitzsimmons, Deborah

    2018-01-01

    Among the challenges in health research is translating interventions from controlled experimental settings to clinical and community settings where chronic disease is managed daily. Pragmatic trials offer a method for testing interventions in real-world settings but are seldom used in OA research. The aim of this study was to evaluate the literature on pragmatic trials in OA research up to August 2016 in order to identify strengths and weaknesses in the design and reporting of these trials. We used established guidelines to assess the degree to which 61 OA studies complied with pragmatic trial design and reporting. We assessed design according to the pragmatic-explanatory continuum indicator summary and reporting according to the pragmatic trials extension of the CONsolidated Standards of Reporting Trials guidelines. None of the pragmatic trials met all 11 criteria evaluated and most of the trials met between 5 and 8 of the criteria. Criteria most often unmet pertained to practitioner expertise (by requiring specialists) and criteria most often met pertained to primary outcome analysis (by using intention-to-treat analysis). Our results suggest a lack of highly pragmatic trials in OA research. We identify this as a point of opportunity to improve research translation, since optimizing the design and reporting of pragmatic trials can facilitate implementation of evidence-based interventions for OA care. © The Author 2017. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  19. Coeducational or Single-Sex Schools? A Review of the Literature. New Zealand Council for Educational Research, Set 76, Number 1 Item 9.

    Science.gov (United States)

    Irving, James

    This article is part of an informational kit for teachers published by the New Zealand Council for Educational Research. The focus of this article is on the advantages and disadvantages of co-educational and single-sex secondary schools as discussed in research efforts from England and New Zealand. (JLL)

  20. Randomised controlled trials in Scandinavian educational research

    DEFF Research Database (Denmark)

    Pontoppidan, Maiken; Keilow, Maria; Dietrichson, Jens

    2018-01-01

    of this paper is to examine the history of randomised controlled trials in Scandinavian compulsory schools (grades 0–10; pupil ages 6-15). Specifically, we investigate drivers and barriers for randomised controlled trials in educational research and the differences between the three Scandinavian countries...... crucial for the implementation of RCTs and are likely more important in smaller countries such as the Scandinavian ones. Supporting institutions have now been established in all three countries, and we believe that the use of RCTs in Scandinavian educational research is likely to continue....... or more interventions were randomly assigned to groups of students and carried out in a school setting with the primary aim of improving the academic performance of children aged 6-15 in grades 0–10 in Denmark, Norway, or Sweden. We included both conducted and ongoing trials. Publications that seemed...

  1. 75 FR 62109 - Gulf of Mexico Fishery Management Council (Council); Public Meetings

    Science.gov (United States)

    2010-10-07

    ... meetings. SUMMARY: The Gulf of Mexico Fishery Management Council (GMFMC) will convene public meetings... Embassy Suites Hotel, 4914 Constitution Ave., Baton Rouge, LA 70808. Council address: Gulf of Mexico... CONTACT: Dr. Stephen Bortone, Executive Director, Gulf of Mexico Fishery Management Council; telephone...

  2. Ethics review of health research on human participants in South Africa.

    Science.gov (United States)

    van Wyk, Christa

    2010-06-01

    In terms of South African legislation, all health research on human participants must be submitted to an accredited research ethics committee for independent ethics review. Health research covers a broad spectrum of research, including clinical trials. This article sets out the ethical-legal framework for the functioning and composition of such committees. It also deals with the newly created National Health Research Ethics Council, which registers and audits health research ethics committees. Special attention is given to the conduct of clinical trials. In conclusion, it is submitted that the National Health Act, the Draft Regulations Relating to Research on Human Subjects, and two sets of ethical guidelines adopted by the Department of Health provide a much needed and coherent ethical-legal framework for research in South Africa.

  3. 78 FR 54868 - New England Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-09-06

    ..., spawning areas and/or dedicated habitat research areas. Prior to a lunch break, the Council will receive an... plaice rebuilding plans, and small-mesh accountability measures (AMs) for the Georges Bank yellowtail... will be addressed. After a lunch break, the Scallop Committee will update the Council on the...

  4. Evaluation and validation of social and psychological markers in randomised trials of complex interventions in mental health: a methodological research programme.

    Science.gov (United States)

    Dunn, Graham; Emsley, Richard; Liu, Hanhua; Landau, Sabine; Green, Jonathan; White, Ian; Pickles, Andrew

    2015-11-01

    The development of the capability and capacity to evaluate the outcomes of trials of complex interventions is a key priority of the National Institute for Health Research (NIHR) and the Medical Research Council (MRC). The evaluation of complex treatment programmes for mental illness (e.g. cognitive-behavioural therapy for depression or psychosis) not only is a vital component of this research in its own right but also provides a well-established model for the evaluation of complex interventions in other clinical areas. In the context of efficacy and mechanism evaluation (EME) there is a particular need for robust methods for making valid causal inference in explanatory analyses of the mechanisms of treatment-induced change in clinical outcomes in randomised clinical trials. The key objective was to produce statistical methods to enable trial investigators to make valid causal inferences about the mechanisms of treatment-induced change in these clinical outcomes. The primary objective of this report is to disseminate this methodology, aiming specifically at trial practitioners. The three components of the research were (1) the extension of instrumental variable (IV) methods to latent growth curve models and growth mixture models for repeated-measures data; (2) the development of designs and regression methods for parallel trials; and (3) the evaluation of the sensitivity/robustness of findings to the assumptions necessary for model identifiability. We illustrate our methods with applications from psychological and psychosocial intervention trials, keeping the technical details to a minimum, leaving the reporting of the more theoretical and mathematically demanding results for publication in appropriate specialist journals. We show how to estimate treatment effects and introduce methods for EME. We explain the use of IV methods and principal stratification to evaluate the role of putative treatment effect mediators and therapeutic process measures. These results are

  5. Efficient design of clinical trials and epidemiological research: is it possible?

    Science.gov (United States)

    Lauer, Michael S; Gordon, David; Wei, Gina; Pearson, Gail

    2017-08-01

    Randomized clinical trials and large-scale, cohort studies continue to have a critical role in generating evidence in cardiovascular medicine; however, the increasing concern is that ballooning costs threaten the clinical trial enterprise. In this Perspectives article, we discuss the changing landscape of clinical research, and clinical trials in particular, focusing on reasons for the increasing costs and inefficiencies. These reasons include excessively complex design, overly restrictive inclusion and exclusion criteria, burdensome regulations, excessive source-data verification, and concerns about the effect of clinical research conduct on workflow. Thought leaders have called on the clinical research community to consider alternative, transformative business models, including those models that focus on simplicity and leveraging of digital resources. We present some examples of innovative approaches by which some investigators have successfully conducted large-scale, clinical trials at relatively low cost. These examples include randomized registry trials, cluster-randomized trials, adaptive trials, and trials that are fully embedded within digital clinical care or administrative platforms.

  6. 76 FR 35481 - NASA Advisory Council; Science Committee; Astrophysics Subcommittee; Meeting

    Science.gov (United States)

    2011-06-17

    ... Update. --Research and Analysis Update. --Wide-Field Infrared Survey Telescope Science Definition Team... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 11-054] NASA Advisory Council; Science... Subcommittee of the NASA Advisory Council (NAC). This subcommittee reports to the Science Committee of the NAC...

  7. Science or public relations? The inside story of the Asbestosis Research Council, 1957-1990.

    Science.gov (United States)

    Tweedale, G

    2000-12-01

    In 1957, the leading British asbestos companies (Turner & Newall, Cape Asbestos, and British Belting & Asbestos) founded the Asbestosis Research Council (ARC). This was a response to rising asbestosis and asbestos cancer mortality in the UK and the attendant political and social problems that threatened the existence of the asbestos industry. An ARC research program was launched, that by the 1970s was mainly based within the Institute of Occupational Medicine at Edinburgh University. By the end of the 1980s, well over a hundred papers had been published with ARC support. The bulk of the work involved animal experiments and the chemical analysis of fibers, but the asbestos companies showed little enthusiasm for wider epidemiological studies or for exploring the cancer threat. The sponsoring companies dictated the ARC's research strategy and also vetted (and sometimes censored) publications; while using the ARC as a counterweight to government regulation and media attacks. The ARC's history highlights the compromises that were made by individual scientists and demonstrates the dilemmas inherent in industry-controlled research. Copyright 2000 Wiley-Liss, Inc.

  8. Assessing Clinical Trial-Associated Workload in Community-Based Research Programs Using the ASCO Clinical Trial Workload Assessment Tool.

    Science.gov (United States)

    Good, Marjorie J; Hurley, Patricia; Woo, Kaitlin M; Szczepanek, Connie; Stewart, Teresa; Robert, Nicholas; Lyss, Alan; Gönen, Mithat; Lilenbaum, Rogerio

    2016-05-01

    Clinical research program managers are regularly faced with the quandary of determining how much of a workload research staff members can manage while they balance clinical practice and still achieve clinical trial accrual goals, maintain data quality and protocol compliance, and stay within budget. A tool was developed to measure clinical trial-associated workload, to apply objective metrics toward documentation of work, and to provide clearer insight to better meet clinical research program challenges and aid in balancing staff workloads. A project was conducted to assess the feasibility and utility of using this tool in diverse research settings. Community-based research programs were recruited to collect and enter clinical trial-associated monthly workload data into a web-based tool for 6 consecutive months. Descriptive statistics were computed for self-reported program characteristics and workload data, including staff acuity scores and number of patient encounters. Fifty-one research programs that represented 30 states participated. Median staff acuity scores were highest for staff with patients enrolled in studies and receiving treatment, relative to staff with patients in follow-up status. Treatment trials typically resulted in higher median staff acuity, relative to cancer control, observational/registry, and prevention trials. Industry trials exhibited higher median staff acuity scores than trials sponsored by the National Institutes of Health/National Cancer Institute, academic institutions, or others. The results from this project demonstrate that trial-specific acuity measurement is a better measure of workload than simply counting the number of patients. The tool was shown to be feasible and useable in diverse community-based research settings. Copyright © 2016 by American Society of Clinical Oncology.

  9. Modifying the Clinical Research Infrastructure at a Dedicated Clinical Trials Unit: Assessment of Trial Development, Activation, and Participant Accrual.

    Science.gov (United States)

    Tang, Chad; Hess, Kenneth R; Sanders, Dwana; Davis, Suzanne E; Buzdar, Aman U; Kurzrock, Razelle; Lee, J Jack; Meric-Bernstam, Funda; Hong, David S

    2017-03-15

    Purpose: Information on processes for trials assessing investigational therapeutics is sparse. We assessed the trial development processes within the Department of Investigational Cancer Therapeutics (ICT) at MD Anderson Cancer Center (Houston, TX) and analyzed their effects on the trial activation timeline and enrolment. Experimental Design: Data were from a prospectively maintained registry that tracks all clinical studies at MD Anderson. From this database, we identified 2,261 activated phase I-III trials; 221 were done at the ICT. ICT trials were matched to trials from other MD Anderson departments by phase, sponsorship, and submission year. Trial performance metrics were compared with paired Wilcoxon signed rank tests. Results: We identified three facets of the ICT research infrastructure: parallel processing of trial approval steps; a physician-led research team; and regular weekly meetings to foster research accountability. Separate analyses were conducted stratified by sponsorship [industry (133 ICT and 133 non-ICT trials) or institutional (68 ICT and 68 non-ICT trials)]. ICT trial development was faster from IRB approval to activation (median difference of 1.1 months for industry-sponsored trials vs. 2.3 months for institutional) and from activation to first enrolment (median difference of 0.3 months for industry vs. 1.2 months for institutional; all matched P infrastructure within a large academic cancer center was associated with efficient trial development and participant accrual. Clin Cancer Res; 23(6); 1407-13. ©2016 AACR . ©2016 American Association for Cancer Research.

  10. Legal rights of client councils and their role in policy of long-term care organisations in the Netherlands

    Directory of Open Access Journals (Sweden)

    Westert Gert P

    2011-09-01

    Full Text Available Abstract Background Legislation demands the establishment of client councils in Dutch nursing homes and residential care facilities. The members of those councils are residents or their representatives. Client councils have the right to participate in the strategic management of long-term care facilities. More specifically, they need to be consulted regarding organisational issues and a right to consent on issues regarding daily living of residents, including CQ-index research. CQ-index research concerns a method that measures, analyses and report clients' experiences about the quality of care. Research questions were: 'Do client councils exercise their rights to be consulted and to give their consent?' and 'What is the role of client councils in the process of measuring clients' experiences with the CQ-index and what is their opinion about the CQ-index?' Methods Postal questionnaires were sent to members of 1,540 client councils of Dutch nursing homes and residential care facilities. The questionnaire focussed on background information and client councils' involvement in decision-making and strategic management. Results The response rate was 34% (n = 524. Most councils consisted of seven members (range: 5 to 12 members. One out of four members participating in the client councils were clients themselves. Although councils have a legal right to be consulted for organisational issues like finance, vision, annual report, and accommodation, less than half the councils (31-46% reported that they exercised this right. The legal right to consent was perceived by 18 to 36% of the councils regarding client care issues like food and drink, complaints registration, respectful treatment, and activities. For CQ-index research, only 18% of the client councils perceived a right to consent. Their rights to choose an approved contractor -who performs CQ-index research- and indicating improvement priorities, were hardly used. Conclusions Client councils play a

  11. Tribulations of a prostate cancer trial - lessons learned from TOAD, a cancer council Victoria and Transtasman Radiation Oncology Group Trial

    International Nuclear Information System (INIS)

    Duchesne, Gillian M.

    2010-01-01

    Full text: From 2004-2009 a total of 226 out of a target of 750 prostate cancer patients have been randomised into the Timing of Androgen Deprivation trial between immediate and delayed androgen deprivation. A screening log was kept by participating centres for the first 928 patients, which documented the reasons for non-entry into the trial; 42.7% of screened patients were ineligible and a further 33.0% were not entered for other reasons. Fewer than 10% of patients cited not wanting to be part of a clinical trial as a reason for non-entry. Strategies to improve recruitment included broadening the eligibility criteria, encouraging international collaboration, the use and support of research nurses in the private health care environment, and the use of phone follow-up. Recruitment will be completed at the number originally intended to inform the interim analysis designed to test the validity of the statistical assumptions, and a combined survival analysis with the Canadian study is planned.

  12. 78 FR 12294 - Gulf of Mexico Fishery Management Council (Council); Public Meetings

    Science.gov (United States)

    2013-02-22

    ... meetings. SUMMARY: The Gulf of Mexico and South Atlantic Fishery Management Councils will convene a Science.... to 4 p.m. EST on Tuesday, March 12, 2013. ADDRESSES: The meeting will be held at the Gulf of Mexico.... Council address: Gulf of Mexico Fishery Management Council, 2203 North Lois Avenue, Suite 1100, Tampa, FL...

  13. 77 FR 69869 - National Advisory Council on Alcohol Abuse and Alcoholism, National Advisory Council on Drug...

    Science.gov (United States)

    2012-11-21

    ... Alcohol Abuse and Alcoholism, National Advisory Council on Drug Abuse, and National Cancer Advisory Board... Advisory Council on Alcohol Abuse and Alcoholism, National Advisory Council on Drug Abuse, and National...: National Advisory Council on Alcohol Abuse and Alcoholism, National Advisory Council on Drug Abuse, and...

  14. What Value Can Qualitative Research Add to Quantitative Research Design? An Example From an Adolescent Idiopathic Scoliosis Trial Feasibility Study.

    Science.gov (United States)

    Toye, Francine; Williamson, Esther; Williams, Mark A; Fairbank, Jeremy; Lamb, Sarah E

    2016-08-09

    Using an example of qualitative research embedded in a non-surgical feasibility trial, we explore the benefits of including qualitative research in trial design and reflect on epistemological challenges. We interviewed 18 trial participants and used methods of Interpretive Phenomenological Analysis. Our findings demonstrate that qualitative research can make a valuable contribution by allowing trial stakeholders to see things from alternative perspectives. Specifically, it can help to make specific recommendations for improved trial design, generate questions which contextualize findings, and also explore disease experience beyond the trial. To make the most out of qualitative research embedded in quantitative design it would be useful to (a) agree specific qualitative study aims that underpin research design, (b) understand the impact of differences in epistemological truth claims, (c) provide clear thematic interpretations for trial researchers to utilize, and (d) include qualitative findings that explore experience beyond the trial setting within the impact plan. © The Author(s) 2016.

  15. Japanese fusion research

    International Nuclear Information System (INIS)

    Uchida, T.

    1987-01-01

    The Japan experience during thirty years in nuclear fusion research is reported, after attending the 1st Geneva Conference in 1955, Osaka University, immedeately began linear pinch study using capacitor bank discharge. Subsequently to his trial several groups were organized to ward fusion R and D at universities in Tokyo, Nagoya, Kyoto, Sendai and son on. Based upon the recommendation of Japan Science Council, Institut of Plasma Physics (IPP) was established at Nagoya University in 1961 When the 1st International Conference on Plasma Physics and Controlled Nuclear Fusion Research was held in Saltzburg. The gloomy Bohm barrier had stood in front of many of experiments at that time. (author) [pt

  16. 77 FR 20792 - New England Fishery Management Council (NEFMC); Public Meeting

    Science.gov (United States)

    2012-04-06

    ... Enforcement offices. During this period, the Council will receive an overview of activities related to the... experimental fishery permit applications that have been made available since the January 2012 Council meeting... ask for approval of research priorities to be used in soliciting proposals funded through the NEFMC's...

  17. 75 FR 31418 - Intermountain Region, Payette National Forest, Council Ranger District; Idaho; Mill Creek-Council...

    Science.gov (United States)

    2010-06-03

    ... Ranger District; Idaho; Mill Creek--Council Mountain Landscape Restoration Project AGENCY: Forest Service... the Mill Creek--Council Mountain Landscape Restoration Project. The approximate 51,900 acre project area is located about two miles east of Council, Idaho. The Mill Creek--Council Mountain Landscape...

  18. Bureaucracy stifles medical research in Britain: a tale of three trials.

    Science.gov (United States)

    Snooks, Helen; Hutchings, Hayley; Seagrove, Anne; Stewart-Brown, Sarah; Williams, John; Russell, Ian

    2012-08-16

    Recent developments aiming to standardise and streamline processes of gaining the necessary approvals to carry out research in the National Health Service (NHS) in the United Kingdom (UK), have resulted in lengthy and costly delays. The national UK governmental Department of Health's Research Governance Framework (RGF) for Health and Social Care requires that appropriate checks be conducted before research involving human participants, their organs, tissues or data can commence in the NHS. As a result, medical research has been subjected to increased regulation and governance, with the requirement for approvals from numerous regulatory and monitoring bodies. In addition, the processes and outcomes of the attribution of costs in NHS research have caused additional difficulties for researchers. The purpose of this paper is to illustrate, through three trial case studies, the difficulties encountered during the set-up and recruitment phases of these trials, related to gaining the necessary ethical and governance approvals and applying for NHS costs to undertake and deliver the research. Empirical evidence about delays and difficulties related to regulation and governance of medical research was gathered during the period 2009-2010 from three UK randomised controlled trials with sites in England, Wales and Scotland (1. SAFER 2- an emergency care based trial of a protocol for paramedics to refer patients directly to community based falls services; 2. COnStRUCT- a trial of two drugs for acute ulcerative colitis; and 3. Family Links - a trial of a public health intervention, a 10 week community based parenting programme). Findings and recommendations were reported in response to a call for evidence from The Academy of Medical Sciences regarding difficulties encountered in conducting medical research arising from R&D governance and regulation, to inform national policy. Difficulties and delays in navigating and gaining the appropriate approvals and NHS costs required to

  19. Getting added value from using qualitative research with randomized controlled trials: a qualitative interview study

    Science.gov (United States)

    2014-01-01

    Background Qualitative research is undertaken with randomized controlled trials of health interventions. Our aim was to explore the perceptions of researchers with experience of this endeavour to understand the added value of qualitative research to the trial in practice. Methods A telephone semi-structured interview study with 18 researchers with experience of undertaking the trial and/or the qualitative research. Results Interviewees described the added value of qualitative research for the trial, explaining how it solved problems at the pretrial stage, explained findings, and helped to increase the utility of the evidence generated by the trial. From the interviews, we identified three models of relationship of the qualitative research to the trial. In ‘the peripheral’ model, the trial was an opportunity to undertake qualitative research, with no intention that it would add value to the trial. In ‘the add-on’ model, the qualitative researcher understood the potential value of the qualitative research but it was viewed as a separate and complementary endeavour by the trial lead investigator and wider team. Interviewees described how this could limit the value of the qualitative research to the trial. Finally ‘the integral’ model played out in two ways. In ‘integral-in-theory’ studies, the lead investigator viewed the qualitative research as essential to the trial. However, in practice the qualitative research was under-resourced relative to the trial, potentially limiting its ability to add value to the trial. In ‘integral-in-practice’ studies, interviewees described how the qualitative research was planned from the beginning of the study, senior qualitative expertise was on the team from beginning to end, and staff and time were dedicated to the qualitative research. In these studies interviewees described the qualitative research adding value to the trial although this value was not necessarily visible beyond the original research team due

  20. Getting added value from using qualitative research with randomized controlled trials: a qualitative interview study.

    Science.gov (United States)

    O'Cathain, Alicia; Goode, Jackie; Drabble, Sarah J; Thomas, Kate J; Rudolph, Anne; Hewison, Jenny

    2014-06-09

    Qualitative research is undertaken with randomized controlled trials of health interventions. Our aim was to explore the perceptions of researchers with experience of this endeavour to understand the added value of qualitative research to the trial in practice. A telephone semi-structured interview study with 18 researchers with experience of undertaking the trial and/or the qualitative research. Interviewees described the added value of qualitative research for the trial, explaining how it solved problems at the pretrial stage, explained findings, and helped to increase the utility of the evidence generated by the trial. From the interviews, we identified three models of relationship of the qualitative research to the trial. In 'the peripheral' model, the trial was an opportunity to undertake qualitative research, with no intention that it would add value to the trial. In 'the add-on' model, the qualitative researcher understood the potential value of the qualitative research but it was viewed as a separate and complementary endeavour by the trial lead investigator and wider team. Interviewees described how this could limit the value of the qualitative research to the trial. Finally 'the integral' model played out in two ways. In 'integral-in-theory' studies, the lead investigator viewed the qualitative research as essential to the trial. However, in practice the qualitative research was under-resourced relative to the trial, potentially limiting its ability to add value to the trial. In 'integral-in-practice' studies, interviewees described how the qualitative research was planned from the beginning of the study, senior qualitative expertise was on the team from beginning to end, and staff and time were dedicated to the qualitative research. In these studies interviewees described the qualitative research adding value to the trial although this value was not necessarily visible beyond the original research team due to the challenges of publishing this research

  1. Participant verification: prevention of co-enrolment in clinical trials in South Africa.

    Science.gov (United States)

    Harichund, C; Haripersad, K; Ramjee, R

    2013-05-15

    As KwaZulu-Natal Province is the epicentre of the HIV epidemic in both South Africa (SA) and globally, it is an ideal location to conduct HIV prevention and therapeutic trials. Numerous prevention trials are currently being conducted here; the potential for participant co-enrolment may compromise the validity of these studies and is therefore of great concern. To report the development and feasibility of a digital, fingerprint-based participant identification method to prevent co-enrolment at multiple clinical trial sites. The Medical Research Council (MRC) HIV Prevention Research Unit (HPRU) developed the Biometric Co-enrolment Prevention System (BCEPS), which uses fingerprint-based biometric technology to identify participants. A trial website was used to determine the robustness and usability of the system. After successful testing, the BCEPS was piloted in July 2010 across 7 HPRU clinical research sites. The BCEPS was pre-loaded with study names and clinical trial sites, with new participant information loaded at first visit to a trial site. We successfully implemented the BCEPS at the 7 HPRU sites. Using the BCEPS, we performed real-time 'flagging' of women who were already enrolled in another study as they entered a trial at an HPRU site and, where necessary, excluded them from participation on site. This system has promise in reducing co-enrolment in clinical trials and represents a valuable tool for future implementation by all groups conducting trials. The MRC is currently co-ordinating this effort with clinical trial sites nationally.

  2. Class Councils in Switzerland: Citizenship Education in Classroom Communities?

    Directory of Open Access Journals (Sweden)

    Corinne Wyss

    2012-09-01

    Full Text Available Democracy depends on the participation of citizens. Citizenship educationis taking place in classroom communities to prepare pupils for their role ascitizens. Class councils are participatory forms of citizenship educationguaranteeing the children’s right to form and express their views freely aswritten down in the Convention on the Rights of the Child. Theoreticaldeficiencies and empirical objections have been formulated againstparticipation in the school setting. Despite widespread practices, empiricaldata about class councils in Switzerland barely exists. In our researchproject we video-recorded fourteen class councils in secondary schools, weinterviewed the teacher and four pupils of each class, and all the pupilsfilled in a standardized questionnaire. Class councils are very popular formsof education with pupils although the actual power to influence decisions bydeliberation is doubted to some extent. Quantitative analysis of the videorecordingsshows the wide range of forms of class councils that exist inrespect to the talking time of the pupils. To express one’s own viewpointand to understand the standpoint of other discussants, constructarguments and counterarguments, participate, and lead discussions aredifficult tasks. Based on the empirical research the project describes threeforms of class councils that differ in the degree of favouring thedevelopment of communicative competences as a part of citizenshipeducation.

  3. Research gaps identified during systematic reviews of clinical trials: glass-ionomer cements.

    Science.gov (United States)

    Mickenautsch, Steffen

    2012-06-29

    To report the results of an audit concerning research gaps in clinical trials that were accepted for appraisal in authored and published systematic reviews regarding the application of glass-ionomer cements (GIC) in dental practice Information concerning research gaps in trial precision was extracted, following a framework that included classification of the research gap reasons: 'imprecision of information (results)', 'biased information', 'inconsistency or unknown consistency' and 'not the right information', as well as research gap characterization using PICOS elements: population (P), intervention (I), comparison (C), outcomes (O) and setting (S). Internal trial validity assessment was based on the understanding that successful control for systematic error cannot be assured on the basis of inclusion of adequate methods alone, but also requires empirical evidence about whether such attempt was successful. A comprehensive and interconnected coverage of GIC-related clinical topics was established. The most common reasons found for gaps in trial precision were lack of sufficient trials and lack of sufficient large sample size. Only a few research gaps were ascribed to 'Lack of information' caused by focus on mainly surrogate trial outcomes. According to the chosen assessment criteria, a lack of adequate randomisation, allocation concealment and blinding/masking in trials covering all reviewed GIC topics was noted (selection- and detection/performance bias risk). Trial results appear to be less affected by loss-to-follow-up (attrition bias risk). This audit represents an adjunct of the systematic review articles it has covered. Its results do not change the systematic review's conclusions but highlight existing research gaps concerning the precision and internal validity of reviewed trials in detail. These gaps should be addressed in future GIC-related clinical research.

  4. Construction of ethics in clinical research: clinical trials registration

    OpenAIRE

    C. A. Caramori

    2007-01-01

    Scientific development that has been achieved through decades finds in clinical research a great possibility of translating findings to human health application. Evidence given by clinical trials allows everyone to have access to the best health services. However, the millionaire world of pharmaceutical industries has stained clinical research with doubt and improbability. Study results (fruits of controlled clinical trials) and scientific publications (selective, manipulated and with wrong c...

  5. APA Council Reports.

    Science.gov (United States)

    2017-10-01

    At the fall component meetings of the American Psychiatric Association in Arlington, Va., September 13-16, 2017, the APA councils heard reports from their components. Following are summaries of the activities of the councils and their components.

  6. Describing qualitative research undertaken with randomised controlled trials in grant proposals: a documentary analysis.

    Science.gov (United States)

    Drabble, Sarah J; O'Cathain, Alicia; Thomas, Kate J; Rudolph, Anne; Hewison, Jenny

    2014-02-18

    There is growing recognition of the value of conducting qualitative research with trials in health research. It is timely to reflect on how this qualitative research is presented in grant proposals to identify lessons for researchers and research commissioners. As part of a larger study focusing on how to maximise the value of undertaking qualitative research with trials, we undertook a documentary analysis of proposals of funded studies. Using the metaRegister of Controlled Trials (mRCT) database we identified trials funded in the United Kingdom, ongoing between 2001 and 2010, and reporting the use of qualitative research. We requested copies of proposals from lead researchers. We extracted data from the proposals using closed and open questions, analysed using descriptive statistics and content analysis respectively. 2% (89/3812) of trials in the mRCT database described the use of qualitative research undertaken with the trial. From these 89 trials, we received copies of 36 full proposals, of which 32 met our inclusion criteria. 25% used less than a single paragraph to describe the qualitative research. The aims of the qualitative research described in these proposals focused mainly on the intervention or trial conduct. Just over half (56%) of the proposals included an explicit rationale for conducting the qualitative research with the trial, the most frequent being to optimise implementation into clinical practice or to interpret trial findings. Key information about methods, expertise and resources was missing in a large minority of proposals, in particular sample size, type of analysis, and non-personnel resources. 28% specifically stated that qualitative researchers would conduct the qualitative research. Our review of proposals of successfully funded studies identified good practice but also identified limited space given to describing the qualitative research, with an associated lack of attention to the rationale for doing the qualitative research and

  7. 78 FR 16505 - Office of the Assistant Secretary for Planning and Evaluation; Advisory Council on Alzheimer's...

    Science.gov (United States)

    2013-03-15

    ... Evaluation; Advisory Council on Alzheimer's Research, Care, and Services AGENCY: Department of Health and... Alzheimer's Research, Care, and Services to fill the position of representative of a voluntary health... Council on Alzheimer's Research, Care, and Services meets quarterly to discuss programs that impact people...

  8. Pharmaceutical companies vs. the State: who is responsible for post-trial provision of drugs in Brazil?

    Science.gov (United States)

    Wang, Daniel Wei L; Ferraz, Octavio Luiz Motta

    2012-01-01

    This paper discusses the post-trial access to drugs for patients who participated in clinical trials in Brazil. The ethical guidance for clinical trials in Brazil is arguably one of the clearest in the world in attributing to research sponsors the responsibility for providing post-trial drugs to patients who participated in their experiments. The Federal Constitution recognizes health as a fundamental right to be fulfilled by the State. Based on the Brazilian constitution and on the National Health Council resolutions, courts have been accepting patients' claims and ordering the State and the pharmaceutical companies to provide these patients with the tested treatment in the quantity and duration they need it. This generous interpretation of the duties of the pharmaceutical companies and the State makes the Brazilian model for post-trial access unique when compared to the experience of other countries and thus should be followed with attention by future research in order to assess its consequences for patients, research sponsors, and the public health system. © 2012 American Society of Law, Medicine & Ethics, Inc.

  9. ITER council proceedings: 1992

    International Nuclear Information System (INIS)

    1994-01-01

    At the signing of the ITER EDA Agreement on July, 1992, each of the Parties presented to the Director General the names of their designated members of the ITER Council. Upon receiving those names, the Director General stated that the ITER Engineering Design Activities were ''ready to begin''. The next step in this process was the convening of the first meeting of the ITER Council. The first meeting of the Council, held in Vienna, was opened by Director General Hans Blix. The second meeting was held in Moscow, the formal seat of the Council. This volume presents records of these first two Council meetings and, together with the previous volumes on the text of the Agreement and Protocol 1 and the preparations for their signing respectively, represents essential information on the evolution of the ITER EDA

  10. Research gaps identified during systematic reviews of clinical trials: glass-ionomer cements

    Directory of Open Access Journals (Sweden)

    Mickenautsch Steffen

    2012-06-01

    Full Text Available Abstract Background To report the results of an audit concerning research gaps in clinical trials that were accepted for appraisal in authored and published systematic reviews regarding the application of glass-ionomer cements (GIC in dental practice Methods Information concerning research gaps in trial precision was extracted, following a framework that included classification of the research gap reasons: ‘imprecision of information (results’, ‘biased information’, ‘inconsistency or unknown consistency’ and ‘not the right information’, as well as research gap characterization using PICOS elements: population (P, intervention (I, comparison (C, outcomes (O and setting (S. Internal trial validity assessment was based on the understanding that successful control for systematic error cannot be assured on the basis of inclusion of adequate methods alone, but also requires empirical evidence about whether such attempt was successful. Results A comprehensive and interconnected coverage of GIC-related clinical topics was established. The most common reasons found for gaps in trial precision were lack of sufficient trials and lack of sufficient large sample size. Only a few research gaps were ascribed to ‘Lack of information’ caused by focus on mainly surrogate trial outcomes. According to the chosen assessment criteria, a lack of adequate randomisation, allocation concealment and blinding/masking in trials covering all reviewed GIC topics was noted (selection- and detection/performance bias risk. Trial results appear to be less affected by loss-to-follow-up (attrition bias risk. Conclusion This audit represents an adjunct of the systematic review articles it has covered. Its results do not change the systematic review’s conclusions but highlight existing research gaps concerning the precision and internal validity of reviewed trials in detail. These gaps should be addressed in future GIC-related clinical research.

  11. Research in Nursing Practice, Education, and Administration: Collaborative, Methodological, and Ethical Implications. Proceedings of the Research Conference of the Southern Council on Collegiate Education for Nursing (3rd, Baltimore, Maryland, December 2-3, 1983).

    Science.gov (United States)

    Strickland, Ora L., Ed.; Damrosch, Shirley P., Ed.

    Collaborative research in nursing is discussed in five papers from the 1983 conference of the Southern Council on Collegiate Education for Nursing. Also included are 32 abstracts of nursing research, focusing on clinical practice, as well as nursing education and research models. Paper titles and authors are as follows: "Building a Climate…

  12. Diversity in Action conference | Council Chamber | 30 September

    CERN Multimedia

    2015-01-01

    Promoting sustainable excellence through diversity in research careers, by Dr Pippa Wells (CERN) and Dr Claartje Vinkenburg (VU University Amsterdam).   Wednesday, 30 September 1.30 p.m. - 3.00 p.m. Council Chamber To register, please click here. Excellence is a non-negotiable in science, a necessary condition for a successful career as well as the funding of research projects. Scientific excellence is the sole criterion used by the European Research Council (ERC) to award frontier research grants. However, statistics show that there are still persistent inequalities between men and women scientists in ERC funding success as well as other career outcomes.  Dr Claartje Vinkenburg, of the VU University of Amsterdam, will illustrate two projects commissioned by the ERC Gender Balance Working Group to uncover and address this phenomenon. The first project [ERCAREER (Vinkenburg PI, 2012-2014)] is about unconventional careers and career breaks...

  13. Consumer input into research: the Australian Cancer Trials website.

    Science.gov (United States)

    Dear, Rachel F; Barratt, Alexandra L; Crossing, Sally; Butow, Phyllis N; Hanson, Susan; Tattersall, Martin Hn

    2011-06-26

    The Australian Cancer Trials website (ACTO) was publicly launched in 2010 to help people search for cancer clinical trials recruiting in Australia, provide information about clinical trials and assist with doctor-patient communication about trials. We describe consumer involvement in the design and development of ACTO and report our preliminary patient evaluation of the website. Consumers, led by Cancer Voices NSW, provided the impetus to develop the website. Consumer representative groups were consulted by the research team during the design and development of ACTO which combines a search engine, trial details, general information about trial participation and question prompt lists. Website use was analysed. A patient evaluation questionnaire was completed at one hospital, one week after exposure to the website. ACTO's main features and content reflect consumer input. In February 2011, it covered 1, 042 cancer trials. Since ACTO's public launch in November 2010, until the end of February 2011, the website has had 2, 549 new visits and generated 17, 833 page views. In a sub-study of 47 patient users, 89% found the website helpful for learning about clinical trials and all respondents thought patients should have access to ACTO. The development of ACTO is an example of consumers working with doctors, researchers and policy makers to improve the information available to people whose lives are affected by cancer and to help them participate in their treatment decisions, including consideration of clinical trial enrolment. Consumer input has ensured that the website is informative, targets consumer priorities and is user-friendly. ACTO serves as a model for other health conditions.

  14. World Radiopharmaceutical Therapy Council: A report on the 5th International Radiopharmaceutical Therapy Colloquium and the Final Planning Meeting of the World Radiopharmaceutical Therapy Council held at Santiago, Chile, 29 September, 2002

    International Nuclear Information System (INIS)

    Turner, J.V.

    2003-01-01

    Full text: The 5th International Radiopharmaceutical Therapy Colloquium was held on 29th October 2002 as a pre-congress meeting of the World Federation of Nuclear Medicine and Biology Congress in Santiago, Chile. Work-in-Progress research papers were presented by leaders in the field of therapeutic nuclear oncology. Speakers gave untitled presentations without abstracts and reported data from studies performed only days or weeks before the meeting. Such cutting edge research presentations stimulated lively discussion which also addressed the problems encountered and ways in which they may be circumvented. Radioimmunotherapy of haematological malignancy was discussed by Greg Wiseman of the Mayo Clinic, and Thomas Behr of the University of Marburg. Radiopeptide therapy of neuroendocrine tumours was presented by Larry Kvols from the University of Florida, and locoregional therapy of glioma was presented by John Buscombe of the Royal Free Hospital, London. All speakers reported encouraging clinical results with objective tumour responses, increased survival and improved quality of life, which encourages wider clinical application of these novel radiopharmaceutical therapies. The Round Table Discussion on clinical applications of Rhenium-188 radiopharmaceuticals was chaired by Russ Knapp from Oak Ridge National Laboratory and Hans Biersack of the University of Bonn. Following an outline of current developments by Russ Knapp preliminary results of clinical trials were presented for discussion. Hans Biersack, Javier Gaudiano from Montevideo and Achim Kropp from Dresden reported effective palliation of painful skeletal metastases with 188Re-HEDP. Ajit Padhy gave an update of the IAEA multicentre trial of intrahepatic arterial 188Re-Lipiodol therapy of hepatocellular carcinoma and Harvey Turner reported preliminary results in hepatoma patients using an alternative kit formulation of 188Re-Lipiodol in Fremantle. Early experience with Rhenium 188 in the prevention of re

  15. Describing qualitative research undertaken with randomised controlled trials in grant proposals: a documentary analysis

    Science.gov (United States)

    2014-01-01

    Background There is growing recognition of the value of conducting qualitative research with trials in health research. It is timely to reflect on how this qualitative research is presented in grant proposals to identify lessons for researchers and research commissioners. As part of a larger study focusing on how to maximise the value of undertaking qualitative research with trials, we undertook a documentary analysis of proposals of funded studies. Methods Using the metaRegister of Controlled Trials (mRCT) database we identified trials funded in the United Kingdom, ongoing between 2001 and 2010, and reporting the use of qualitative research. We requested copies of proposals from lead researchers. We extracted data from the proposals using closed and open questions, analysed using descriptive statistics and content analysis respectively. Results 2% (89/3812) of trials in the mRCT database described the use of qualitative research undertaken with the trial. From these 89 trials, we received copies of 36 full proposals, of which 32 met our inclusion criteria. 25% used less than a single paragraph to describe the qualitative research. The aims of the qualitative research described in these proposals focused mainly on the intervention or trial conduct. Just over half (56%) of the proposals included an explicit rationale for conducting the qualitative research with the trial, the most frequent being to optimise implementation into clinical practice or to interpret trial findings. Key information about methods, expertise and resources was missing in a large minority of proposals, in particular sample size, type of analysis, and non-personnel resources. 28% specifically stated that qualitative researchers would conduct the qualitative research. Conclusions Our review of proposals of successfully funded studies identified good practice but also identified limited space given to describing the qualitative research, with an associated lack of attention to the rationale for

  16. When ethics constrains clinical research: trial design of control arms in "greater than minimal risk" pediatric trials.

    Science.gov (United States)

    de Melo-Martín, Inmaculada; Sondhi, Dolan; Crystal, Ronald G

    2011-09-01

    For more than three decades clinical research in the United States has been explicitly guided by the idea that ethical considerations must be central to research design and practice. In spite of the centrality of this idea, attempting to balance the sometimes conflicting values of advancing scientific knowledge and protecting human subjects continues to pose challenges. Possible conflicts between the standards of scientific research and those of ethics are particularly salient in relation to trial design. Specifically, the choice of a control arm is an aspect of trial design in which ethical and scientific issues are deeply entwined. Although ethical quandaries related to the choice of control arms may arise when conducting any type of clinical trials, they are conspicuous in early phase gene transfer trials that involve highly novel approaches and surgical procedures and have children as the research subjects. Because of children's and their parents' vulnerabilities, in trials that investigate therapies for fatal, rare diseases affecting minors, the scientific and ethical concerns related to choosing appropriate controls are particularly significant. In this paper we use direct gene transfer to the central nervous system to treat late infantile neuronal ceroid lipofuscinosis to illustrate some of these ethical issues and explore possible solutions to real and apparent conflicts between scientific and ethical considerations.

  17. Appraisal of the Effectiveness of CODE; The Coordinated Delivery System for the South Central Research Library Council, January to December 1970.

    Science.gov (United States)

    Faibisoff, Sylvia G.

    A major concern of the South Central Research Library Council in establishing an interlibrary loan network was the development of a Coordinated Delivery system (CODE). Several means of delivery were considered--the U.S. mails, commercial trucking (Greyhound, United Parcel Service), and use of the public library system's delivery services. A…

  18. European works councils

    DEFF Research Database (Denmark)

    Knudsen, Herman Lyhne

    2004-01-01

    The theme addressed by this artcle is the opportunities for European Works Councils of gaining influence on corporate decisions in multinational companies.......The theme addressed by this artcle is the opportunities for European Works Councils of gaining influence on corporate decisions in multinational companies....

  19. Identifying research priorities for effective retention strategies in clinical trials.

    Science.gov (United States)

    Kearney, Anna; Daykin, Anne; Shaw, Alison R G; Lane, Athene J; Blazeby, Jane M; Clarke, Mike; Williamson, Paula; Gamble, Carrol

    2017-08-31

    The failure to retain patients or collect primary-outcome data is a common challenge for trials and reduces the statistical power and potentially introduces bias into the analysis. Identifying strategies to minimise missing data was the second highest methodological research priority in a Delphi survey of the Directors of UK Clinical Trial Units (CTUs) and is important to minimise waste in research. Our aim was to assess the current retention practices within the UK and priorities for future research to evaluate the effectiveness of strategies to reduce attrition. Seventy-five chief investigators of NIHR Health Technology Assessment (HTA)-funded trials starting between 2009 and 2012 were surveyed to elicit their awareness about causes of missing data within their trial and recommended practices for improving retention. Forty-seven CTUs registered within the UKCRC network were surveyed separately to identify approaches and strategies being used to mitigate missing data across trials. Responses from the current practice surveys were used to inform a subsequent two-round Delphi survey with registered CTUs. A consensus list of retention research strategies was produced and ranked by priority. Fifty out of seventy-five (67%) chief investigators and 33/47 (70%) registered CTUs completed the current practice surveys. Seventy-eight percent of trialists were aware of retention challenges and implemented strategies at trial design. Patient-initiated withdrawal was the most common cause of missing data. Registered CTUs routinely used newsletters, timeline of participant visits, and telephone reminders to mitigate missing data. Whilst 36 out of 59 strategies presented had been formally or informally evaluated, some frequently used strategies, such as site initiation training, have had no research to inform practice. Thirty-five registered CTUs (74%) participated in the Delphi survey. Research into the effectiveness of site initiation training, frequency of patient contact

  20. Report from Council

    CERN Document Server

    2015-01-01

    This week’s Council meeting was dominated by discussions about the long-term, sustainable future of CERN. Key points are progress on the Medium-Term Plan, the successful LHC restart, and enlargement.   The budget proposed by management for 2016 was well received, as were the measures to mitigate against the recent change in exchange rates. These items will be put to the vote in September. Discussions on CERN staff employment conditions were conducted in a constructive atmosphere this week, and will continue in future Council meetings. The Council also clearly voiced its congratulations for the smooth and successful start of LHC run 2, coming on top of a clear run of spectacular scientific and technological successes over recent years. In the current climate of austerity, these developments are a strong endorsement from the Council. Nevertheless, it would be disingenuous of me to pretend that everything is rosy. There has been an air of unease at CERN over recent months, which was v...

  1. Legal Status Of The Election Organizer Ethics Council An Analysis Of Indonesian Election Systems

    Directory of Open Access Journals (Sweden)

    Ardin

    2015-08-01

    Full Text Available This research aims to identify and to analyze the legal status of the Election Organizer Ethics Council in the General Election in Indonesia. This research is a normative research by using statute approach official records and the judges verdict which is then described qualitatively. These results indicate that the legal status of the Election Organizer Ethics Council in the general election in Indonesia as supporting organ that serves to uphold ethics rule of ethics and guarding democracy. The authority of Election Organizer Ethics Council in the general election in Indonesia sometimes out of authority. Ideal concept of the legal status of the Election Organizer Ethics Council in general elections was as supporting organ which have the infrastructure secretary general and administrative staff so it has a public legal entity as similar to the Election organizers serve as code of ethics enforcement agencies code of ethics and can equated to other state institutions.

  2. Consumer input into research: the Australian Cancer Trials website

    Directory of Open Access Journals (Sweden)

    Butow Phyllis N

    2011-06-01

    Full Text Available Abstract Background The Australian Cancer Trials website (ACTO was publicly launched in 2010 to help people search for cancer clinical trials recruiting in Australia, provide information about clinical trials and assist with doctor-patient communication about trials. We describe consumer involvement in the design and development of ACTO and report our preliminary patient evaluation of the website. Methods Consumers, led by Cancer Voices NSW, provided the impetus to develop the website. Consumer representative groups were consulted by the research team during the design and development of ACTO which combines a search engine, trial details, general information about trial participation and question prompt lists. Website use was analysed. A patient evaluation questionnaire was completed at one hospital, one week after exposure to the website. Results ACTO's main features and content reflect consumer input. In February 2011, it covered 1, 042 cancer trials. Since ACTO's public launch in November 2010, until the end of February 2011, the website has had 2, 549 new visits and generated 17, 833 page views. In a sub-study of 47 patient users, 89% found the website helpful for learning about clinical trials and all respondents thought patients should have access to ACTO. Conclusions The development of ACTO is an example of consumers working with doctors, researchers and policy makers to improve the information available to people whose lives are affected by cancer and to help them participate in their treatment decisions, including consideration of clinical trial enrolment. Consumer input has ensured that the website is informative, targets consumer priorities and is user-friendly. ACTO serves as a model for other health conditions.

  3. Understanding and Improving Recruitment to Randomised Controlled Trials: Qualitative Research Approaches.

    Science.gov (United States)

    Elliott, Daisy; Husbands, Samantha; Hamdy, Freddie C; Holmberg, Lars; Donovan, Jenny L

    2017-11-01

    The importance of evidence from randomised trials is now widely recognised, although recruitment is often difficult. Qualitative research has shown promise in identifying the key barriers to recruitment, and interventions have been developed to reduce organisational difficulties and support clinicians undertaking recruitment. This article provides an introduction to qualitative research techniques and explains how this approach can be used to understand-and subsequently improve-recruitment and informed consent within a range of clinical trials. A literature search was performed using Medline, Embase, and CINAHL. All studies with qualitative research methods that focused on the recruitment activity of clinicians were included in the review. The majority of studies reported that organisational difficulties and lack of time for clinical staff were key barriers to recruitment. However, a synthesis of qualitative studies highlighted the intellectual and emotional challenges that arise when combining research with clinical roles, particularly in relation to equipoise and patient eligibility. To support recruiters to become more comfortable with the design and principles of randomised controlled trials, interventions have been developed, including the QuinteT Recruitment Intervention, which comprises in-depth investigation of recruitment obstacles in real time, followed by implementation of tailored strategies to address these challenges as the trial proceeds. Qualitative research can provide important insights into the complexities of recruitment to trials and inform the development of interventions, and provide support and training initiatives as required. Investigators should consider implementing such methods in trials expected to be challenging or recruiting below target. Qualitative research is a term used to describe a range of methods that can be implemented to understand participants' perspectives and behaviours. Data are gathered from interviews, focus groups

  4. 76 FR 54216 - Pacific Fishery Management Council (Council); Work Session To Review Proposed Salmon Methodology...

    Science.gov (United States)

    2011-08-31

    ... Fishery Management Council (Council); Work Session To Review Proposed Salmon Methodology Changes AGENCY.... ACTION: Notice of a public meeting. SUMMARY: The Pacific Fishery Management Council's Salmon Technical Team (STT), Scientific and Statistical Committee (SSC) Salmon Subcommittee, and Model Evaluation...

  5. 78 FR 41914 - South Atlantic Fishery Management Council (Council); Public Meetings

    Science.gov (United States)

    2013-07-12

    ... Atlantic Fishery Management Council (Council); Public Meetings AGENCY: National Marine Fisheries Service... as well as Framework actions to the Coastal Migratory Pelagics FMP. DATES: The meetings will be held... and Framework Actions to the Coastal Migratory Pelagics (CMP) FMP 1. Amendment 19 is a joint Gulf of...

  6. 7 CFR 1218.23 - U.S. Highbush Blueberry Council.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false U.S. Highbush Blueberry Council. 1218.23 Section 1218... SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Definitions...

  7. From bricks to buildings: adapting the Medical Research Council framework to develop programs of research in simulation education and training for the health professions.

    Science.gov (United States)

    Haji, Faizal A; Da Silva, Celina; Daigle, Delton T; Dubrowski, Adam

    2014-08-01

    Presently, health care simulation research is largely conducted on a study-by-study basis. Although such "project-based" research generates a plethora of evidence, it can be chaotic and contradictory. A move toward sustained, thematic, theory-based programs of research is necessary to advance knowledge in the field. Recognizing that simulation is a complex intervention, we present a framework for developing research programs in simulation-based education adapted from the Medical Research Council (MRC) guidance. This framework calls for an iterative approach to developing, refining, evaluating, and implementing simulation interventions. The adapted framework guidance emphasizes: (1) identification of theory and existing evidence; (2) modeling and piloting interventions to clarify active ingredients and identify mechanisms linking the context, intervention, and outcomes; and (3) evaluation of intervention processes and outcomes in both the laboratory and real-world setting. The proposed framework will aid simulation researchers in developing more robust interventions that optimize simulation-based education and advance our understanding of simulation pedagogy.

  8. Does clinical equipoise apply to cluster randomized trials in health research?

    Science.gov (United States)

    2011-01-01

    This article is part of a series of papers examining ethical issues in cluster randomized trials (CRTs) in health research. In the introductory paper in this series, Weijer and colleagues set out six areas of inquiry that must be addressed if the cluster trial is to be set on a firm ethical foundation. This paper addresses the third of the questions posed, namely, does clinical equipoise apply to CRTs in health research? The ethical principle of beneficence is the moral obligation not to harm needlessly and, when possible, to promote the welfare of research subjects. Two related ethical problems have been discussed in the CRT literature. First, are control groups that receive only usual care unduly disadvantaged? Second, when accumulating data suggests the superiority of one intervention in a trial, is there an ethical obligation to act? In individually randomized trials involving patients, similar questions are addressed by the concept of clinical equipoise, that is, the ethical requirement that, at the start of a trial, there be a state of honest, professional disagreement in the community of expert practitioners as to the preferred treatment. Since CRTs may not involve physician-researchers and patient-subjects, the applicability of clinical equipoise to CRTs is uncertain. Here we argue that clinical equipoise may be usefully grounded in a trust relationship between the state and research subjects, and, as a result, clinical equipoise is applicable to CRTs. Clinical equipoise is used to argue that control groups receiving only usual care are not disadvantaged so long as the evidence supporting the experimental and control interventions is such that experts would disagree as to which is preferred. Further, while data accumulating during the course of a CRT may favor one intervention over another, clinical equipoise supports continuing the trial until the results are likely to be broadly convincing, often coinciding with the planned completion of the trial

  9. 77 FR 1670 - Gulf of Mexico Fishery Management Council (Council); Public Meetings

    Science.gov (United States)

    2012-01-11

    ... INFORMATION CONTACT: Dr. Stephen Bortone, Executive Director, Gulf of Mexico Fishery Management Council....--Scientific & Statistical Committee (SSC) Selection Committee will discuss duties and responsibilities of the... p.m.--Scientific & Statistical Committee (SSC) Selection Committee--Full Council (Closed Session...

  10. Why we need easy access to all data from all clinical trials and how to accomplish it

    DEFF Research Database (Denmark)

    Gotzsche, Peter C

    2011-01-01

    ABSTRACT: International calls for registering all trials involving humans and for sharing the results, and sometimes also the raw data and the trial protocols, have increased in recent years. Such calls have come, for example, from the Organization for Economic Cooperation and Development (OECD......), the World Health Organization (WHO), the US National Institutes of Heath, the US Congress, the European Commission, the European ombudsman, journal editors, The Cochrane Collaboration, and several funders, for example the UK Medical Research Council, the Wellcome Trust, the Bill and Melinda Gates Foundation...... why it is a moral imperative to render all results from all trials involving humans, also healthy volunteers, publicly available. Respect for trial participants who often run a personal and unknown risk by participating in trials requires that they - and therefore also the society at large...

  11. A report from Council

    CERN Multimedia

    2014-01-01

    The June meeting of Council is always a very busy one, having approval of the next year’s budget and the MTP as fixed agenda points. This year in addition, we had discussions on enlargement, as well as on the pension fund. I’d like to use this message to bring you up to date on all of those matters.   I’ll begin with the good news that the 2015 budget and MTP were recommended for approval by Finance Committee on Wednesday, and approved by Council on Thursday. This is extremely good news, and a solid vote of confidence from Council in the current economic situation. Coupled with that, I am pleased to report that at the half way stage of 2014, some 89% of budget contributions for the year have been received. Turning now to enlargement, I can inform you that the task force that went to Pakistan came back with a positive report, and as a consequence Council has authorised us to finalise discussion with Pakistan for Associate Membership. Council also authoris...

  12. 76 FR 34074 - Office of the Assistant Secretary for Planning and Evaluation; Advisory Council on Alzheimer's...

    Science.gov (United States)

    2011-06-10

    ... Evaluation; Advisory Council on Alzheimer's Research, Care, and Services AGENCY: Office of the Assistant... establishment of the Advisory Council on Alzheimer's Research, Care, and Services and request for nominations. SUMMARY: The National Alzheimer's Project Act, Public Law 111-375 (42 U.S.C. 11225), requires that the...

  13. Design and development of a film-based intervention about teenage men and unintended pregnancy: Applying the Medical Research Council framework in practice.

    LENUS (Irish Health Repository)

    Aventin, Aine

    2014-11-15

    Following the UK Medical Research Council\\'s (MRC) guidelines for the development and evaluation of complex interventions, this study aimed to design, develop and optimise an educational intervention about young men and unintended teenage pregnancy based around an interactive film. The process involved identification of the relevant evidence base, development of a theoretical understanding of the phenomenon of unintended teenage pregnancy in relation to young men, and exploratory mixed methods research. The result was an evidence-based, theory-informed, user-endorsed intervention designed to meet the much neglected pregnancy education needs of teenage men and intended to increase both boys\\' and girls\\' intentions to avoid an unplanned pregnancy during adolescence. In prioritising the development phase, this paper addresses a gap in the literature on the processes of research-informed intervention design. It illustrates the application of the MRC guidelines in practice while offering a critique and additional guidance to programme developers on the MRC prescribed processes of developing interventions. Key lessons learned were: (1) know and engage the target population and engage gatekeepers in addressing contextual complexities; (2) know the targeted behaviours and model a process of change; and (3) look beyond development to evaluation and implementation.

  14. The Ethics of Clinical Trials Research in Severe Mood Disorders.

    Science.gov (United States)

    Nugent, Allison C; Miller, Franklin G; Henter, Ioline D; Zarate, Carlos A

    2017-07-01

    Mood disorders, including major depressive disorder (MDD) and bipolar disorder (BD), are highly prevalent, frequently disabling, and sometimes deadly. Additional research and more effective medications are desperately needed, but clinical trials research in mood disorders is fraught with ethical issues. Although many authors have discussed these issues, most do so from a theoretical viewpoint. This manuscript uses available empirical data to inform a discussion of the primary ethical issues raised in mood disorders research. These include issues of consent and decision-making capacity, including patients' motivations for participating in research. We also address drug withdrawals, placebo controls, and the overall safety of research. Finally, we examine the extant literature for studies discussing potential indirect benefits of clinical trials research to participants. Taken together, the evidence suggests that clinical trials research incorporating drug withdrawals and placebo controls can be conducted safely and ethically, even in patients with severe or treatment-resistant mood disorders. In fact, given the dearth of effective treatment options for this population, it is our opinion that a moral imperative exists to extend the offer of research participation to severely ill or treatment-resistant groups. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.

  15. Supporting open access to clinical trial data for researchers: The Duke Clinical Research Institute-Bristol-Myers Squibb Supporting Open Access to Researchers Initiative.

    Science.gov (United States)

    Pencina, Michael J; Louzao, Darcy M; McCourt, Brian J; Adams, Monique R; Tayyabkhan, Rehbar H; Ronco, Peter; Peterson, Eric D

    2016-02-01

    There are growing calls for sponsors to increase transparency by providing access to clinical trial data. In response, Bristol-Myers Squibb and the Duke Clinical Research Institute have collaborated on a new initiative, Supporting Open Access to Researchers. The aim is to facilitate open sharing of Bristol-Myers Squibb trial data with interested researchers. Key features of the Supporting Open Access to Researchers data sharing model include an independent review committee that ensures expert consideration of each proposal, stringent data deidentification/anonymization and protection of patient privacy, requirement of prespecified statistical analysis plans, and independent review of manuscripts before submission for publication. We believe that these approaches will promote open science by allowing investigators to verify trial results as well as to pursue interesting secondary uses of trial data without compromising scientific integrity. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. Practical and conceptual issues of clinical trial registration for Brazilian researchers

    Directory of Open Access Journals (Sweden)

    Carolina Gomes Freitas

    Full Text Available CONTEXT AND OBJECTIVE: Clinical trial registration is a prerequisite for publication in respected scientific journals. Recent Brazilian regulations also require registration of some clinical trials in the Brazilian Clinical Trials Registry (ReBEC but there is little information available about practical issues involved in the registration process. This article discusses the importance of clinical trial registration and the practical issues involved in this process. DESIGN AND SETTING: Descriptive study conducted by researchers within a postgraduate program at a public university in São Paulo, Brazil. METHODS: Information was obtained from clinical trial registry platforms, article reference lists and websites (last search: September 2014 on the following topics: definition of a clinical trial, history, purpose and importance of registry platforms, the information that should be registered and the registration process. RESULTS: Clinical trial registration aims to avoid publication bias and is required by Brazilian journals indexed in LILACS and SciELO and by journals affiliated to the International Committee of Medical Journal Editors (ICMJE. Recent Brazilian regulations require that all clinical trials (phases I to IV involving new drugs to be marketed in this country must be registered in ReBEC. The pros and cons of using different clinical trial registration platforms are discussed. CONCLUSIONS: Clinical trial registration is important and various mechanisms to enforce its implementation now exist. Researchers should take into account national regulations and publication requirements when choosing the platform on which they will register their trial.

  17. Clinical Trials: A Crucial Key to Human Health Research

    Science.gov (United States)

    ... Past Issues Clinical Trials: A Crucial Key to Human Health Research Past Issues / Summer 2006 Table of Contents ... Javascript on. Photo: PhotoDisc At the forefront of human health research today are clinical trials—studies that use ...

  18. Shedding light on research participation effects in behaviour change trials: a qualitative study examining research participant experiences.

    Science.gov (United States)

    MacNeill, Virginia; Foley, Marian; Quirk, Alan; McCambridge, Jim

    2016-01-29

    The sequence of events in a behaviour change trial involves interactions between research participants and the trial process. Taking part in such a study has the potential to influence the behaviour of the participant, and if it does, this can engender bias in trial outcomes. Since participants' experience has received scant attention, the aim of this study is thus to generate hypotheses about which aspects of the conduct of behaviour change trials might matter most to participants, and thus have potential to alter subsequent behaviours and bias trial outcomes Twenty participants were opportunistically screened for a health compromising behaviour (unhealthy diet, lack of exercise, smoking or alcohol consumption) and recruited if eligible. Semi structured face to face interviews were conducted, after going through the usual processes involved in trial recruitment, baseline assessment and randomisation. Participants were given information on the contents of an intervention or control condition in a behaviour change trial, which was not actually implemented. Three months later they returned to reflect on these experiences and whether they had any effect on their behaviour during the intervening period. Data from the latter interview were analysed thematically using a modified grounded theory approach. The early processes of trial participation raised awareness of unhealthy behaviours, although most reported having had only fleeting intentions to change their behaviour as a result of taking part in this study, in the absence of interventions. However, careful examination of the accounts revealed evidence of subtle research participation effects, which varied according to the health behaviour, and its perceived social acceptability. Participants' relationships with the research study were viewed as somewhat important in stimulating thinking about whether and how to make lifestyle changes. These participants described no dramatic impacts attributable to taking part in

  19. ITER council proceedings: 2001

    International Nuclear Information System (INIS)

    2001-01-01

    Continuing the ITER EDA, two further ITER Council Meetings were held since the publication of ITER EDA documentation series no, 20, namely the ITER Council Meeting on 27-28 February 2001 in Toronto, and the ITER Council Meeting on 18-19 July in Vienna. That Meeting was the last one during the ITER EDA. This volume contains records of these Meetings, including: Records of decisions; List of attendees; ITER EDA status report; ITER EDA technical activities report; MAC report and advice; Final report of ITER EDA; and Press release

  20. Advances in cardiovascular research. 15th Annual Meeting of the European Council for Cardiovascular Research (ECCR). La Colle sur Loup, France, 8–10 October 2010.

    Science.gov (United States)

    Steckelings, U Muscha; De Mey, Jo G R; Pinto-Sietsma, Sara-Joan; Henrion, Daniel; Unger, Thomas

    2011-01-01

    The 15th Annual Meeting of the European Council of Cardiovascular Research brought together basic and clinical scientists working in the cardiovascular field in La Colle sur Loup, France. Upfront basic and clinical research addressing the mechanisms of disease, identification of biomarkers or development of new treatments was communicated in 101 presentations, 35 of them as a part of five on-topic oral sessions and three workshops. Three keynote lectures reviewed current knowledge and the latest data about mechanosensitive channels in pressure regulation, cell therapy in cardiovascular disease and mechanisms of cardiovascular risk associated with diabetic nephropathy. This article summarizes highlights of the oral sessions, workshops and keynote lectures.

  1. Big-pharmaceuticalisation: clinical trials and Contract Research Organisations in India.

    Science.gov (United States)

    Sariola, Salla; Ravindran, Deapica; Kumar, Anand; Jeffery, Roger

    2015-04-01

    The World Trade Organisation's Trade Related Intellectual Property Rights [TRIPS] agreement aimed to harmonise intellectual property rights and patent protection globally. In India, the signing of this agreement resulted in a sharp increase in clinical trials since 2005. The Indian government, along with larger Indian pharmaceutical companies, believed that they could change existing commercial research cultures through the promotion of basic research as well as attracting international clinical trials, and thus create an international level, innovation-based drug industry. The effects of the growth of these outsourced and off-shored clinical trials on local commercial knowledge production in India are still unclear. What has been the impact of the increasing scale and commercialisation of clinical research on corporate science in India? In this paper we describe Big-pharmaceuticalisation in India, whereby the local pharmaceutical industry is moving from generic manufacturing to innovative research. Using conceptual frameworks of pharmaceuticalisation and innovation, this paper analyses data from research conducted in 2010-2012 and describes how Contract Research Organisations (CROs) enable outsourcing of randomised control trials to India. Focussing on twenty-five semi-structured interviews CRO staff, we chart the changes in Indian pharmaceutical industry, and implications for local research cultures. We use Big-pharmaceuticalisation to extend the notion of pharmaceuticalisation to describe the spread of pharmaceutical research globally and illustrate how TRIPS has encouraged a concentration of capital in India, with large companies gaining increasing market share and using their market power to rewrite regulations and introduce new regulatory practices in their own interest. Contract Research Organisations, with relevant, new, epistemic skills and capacities, are both manifestations of the changes in commercial research cultures, as well as the vehicles to

  2. [An Investigation of the Role Responsibilities of Clinical Research Nurses in Conducting Clinical Trials].

    Science.gov (United States)

    Kao, Chi-Yin; Huang, Guey-Shiun; Dai, Yu-Tzu; Pai, Ya-Ying; Hu, Wen-Yu

    2015-06-01

    Clinical research nurses (CRNs) play an important role in improving the quality of clinical trials. In Taiwan, the increasing number of clinical trials has increased the number of practicing CRNs. Understanding the role responsibilities of CRNs is necessary to promote professionalism in this nursing category. This study investigates the role responsibilities of CRNs in conducting clinical trials / research. A questionnaire survey was conducted in a medical center in Taipei City, Taiwan. Eighty CRNs that were registered to facilitate and conduct clinical trials at this research site completed the survey. "Subject protection" was the CRN role responsibility most recognized by participants, followed by "research coordination and management", "subject clinical care", and "advanced professional nursing". Higher recognition scores were associated with higher importance scores and lower difficulty scores. Participants with trial training had significantly higher difficulty scores for "subject clinical care" and "research coordination and management" than their peers without this training (p research coordination and management" (p clinical practice.

  3. The UK clinical research network--has it been a success for dermatology clinical trials?

    Science.gov (United States)

    Thomas, Kim S; Koller, Karin; Foster, Katharine; Perdue, Jo; Charlesworth, Lisa; Chalmers, Joanne R

    2011-06-16

    Following the successful introduction of five topic-specific research networks in the UK, the Comprehensive Local Research Network (CLRN) was established in 2008 in order to provide a blanket level of support across the whole country regardless of the clinical discipline. The role of the CLRN was to facilitate recruitment into clinical trials, and to encourage greater engagement in research throughout the National Health Service (NHS). This report evaluates the impact of clinical research networks in supporting clinical trials in the UK, with particular reference to our experiences from two non-commercial dermatology trials. It covers our experience of engaging with the CLRN (and other research networks) using two non-commercial dermatology trials as case studies. We present the circumstances that led to our approach to the research networks for support, and the impact that this support had on the delivery of these trials. In both cases, recruitment was boosted considerably following the provision of additional support, although other factors such as the availability of experienced personnel, and the role of advertising and media coverage in promoting the trials were also important in translating this additional resource into increased recruitment. Recruitment into clinical trials is a complex task that can be influenced by many factors. A world-class clinical research infrastructure is now in place in England (with similar support available in Scotland and Wales), and it is the responsibility of the research community to ensure that this unique resource is used effectively and responsibly.

  4. Strengthening Africa's science granting councils as champions of ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Science granting councils are central to funding and catalyzing research and innovation, particularly in national science systems in sub-Saharan Africa. The availability of reliable indicators—to monitor Africa's scientific and technological developments, implement science policies and strategies, track public investment in ...

  5. 78 FR 44187 - National Women's Business Council

    Science.gov (United States)

    2013-07-23

    ... SMALL BUSINESS ADMINISTRATION National Women's Business Council ACTION: Notice of open Federal..., and agenda for the next meeting of the National Women's Business Council (NWBC). The meeting will be... the meeting of the National Women's Business Council. The National Women's Business Council is tasked...

  6. Regulatory Framework for Conducting Clinical Research in Canada.

    Science.gov (United States)

    Alas, Josmar K; Godlovitch, Glenys; Mohan, Connie M; Jelinski, Shelly A; Khan, Aneal A

    2017-09-01

    Research in human subjects is at the core of achieving improvements in health outcomes. For clinical trials, in addition to the peer review of the results before publication, it is equally important to consider whether the trial will be conducted in a manner that generates data of the highest quality and provides a measure of safety for the participating subjects. In Canada, there is no definitive legislation that governs the conduct of research involving human subjects, but a network of regulations at different levels does provide a framework for both principal investigators and sponsors. In this paper, we provide an overview of the federal, provincial and institutional legislation, guidelines and policies that will inform readers about the requirements for clinical trial research. This includes a review of the role of the Food and Drug Regulations under the Food and Drugs Act and the Tri-Council Policy Statement (TCPS2), an overview of provincial legislation across the country, and a focus on selected policies from institutional research ethics boards and public health agencies. Many researchers may find navigation through regulations frustrating, and there is a paucity of information that explains the interrelationship between the different regulatory agencies in Canada. Better understanding the process, we feel, will facilitate investigators interested in clinical trials and also enhance the long-term health of Canadians.

  7. Elections to Staff Council

    CERN Multimedia

    Saff Association

    2013-01-01

    2013 Elections to Staff Council   Vote! Make your voice heard and be many to elect the new Staff Council. More details on the elections can be found on the Staff Association web site (https://ap-vote.web.cern.ch/elections-2013).   Timetable elections Monday 28 October to Monday 11 November, 12:00 am voting Monday 18 and Monday 25 November, publication of the results in Echo Tuesday 19 November, Staff Association Assizes Tuesday 3 December, first meeting of the new Staff Council and election of the new Executive Committee The voting procedure is monitored by the Election Committee.

  8. Members of the State Council of Geneva

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    Luncheon hosted by the Director-General for members of the State Council of Geneva: From left to right A. Naudi; J. May; M. Carlo Lamprecht, State Council - Employement, Foreign Office and Economic Departement; M. Robert Hensler, State Chancellor; L. Maiani, CERN Director General; H.F. Hoffmann; M. Robert Cramer, State Council - Environment, Agriculture and Interior Departement; J.Van Der Boon; M. Laurent Moutinot, State Council - Installation, equipment and housing Departement; C. Détraz; C. Wyss; P. Jenni; G. Hentsch; M. Pierre-François Unger, State Council - Health and Social Action Departement; G. Stassinakis; M. Bourquin, CERN Council President.

  9. Researchers', Regulators', and Sponsors' Views on Pediatric Clinical Trials: A Multinational Study.

    Science.gov (United States)

    Joseph, Pathma D; Craig, Jonathan C; Tong, Allison; Caldwell, Patrina H Y

    2016-10-01

    The last decade has seen dramatic changes in the regulatory landscape to support more trials involving children, but child-specific challenges and inequitable conduct across income regions persist. The goal of this study was to describe the attitudes and opinions of stakeholders toward trials in children, to inform additional strategies to promote more high-quality, relevant pediatric trials across the globe. Key informant semi-structured interviews were conducted with stakeholders (researchers, regulators, and sponsors) who were purposively sampled from low- to middle-income countries and high-income countries. The transcripts were thematically analyzed. Thirty-five stakeholders from 10 countries were interviewed. Five major themes were identified: addressing pervasive inequities (paucity of safety and efficacy data, knowledge disparities, volatile environment, double standards, contextual relevance, market-driven forces, industry sponsorship bias and prohibitive costs); contending with infrastructural barriers (resource constraints, dearth of pediatric trial expertise, and logistical complexities); navigating complex ethical and regulatory frameworks ("draconian" oversight, ambiguous requirements, exploitation, excessive paternalism and precariousness of coercion versus volunteerism); respecting uniqueness of children (pediatric research paradigms, child-appropriate approaches, and family-centered empowerment); and driving evidence-based child health (advocacy, opportunities, treatment access, best practices, and research prioritization). Stakeholders acknowledge that changes in the regulatory environment have encouraged more trials in children, but they contend that inequities and political, regulatory, and resource barriers continue to exist. Embedding trials as part of routine clinical care, addressing the unique needs of children, and streamlining regulatory approvals were suggested. Stakeholders recommended increasing international collaboration

  10. The South African Medical Research Council's Guidelines on Ethics ...

    African Journals Online (AJOL)

    Children are at risk of HIV infection, stand to benefit from the development of HIV preventive vaccines, and therefore should be enrolled in trials of HIV vaccines in order to generate relevant safety, immunogenicity and efficacy data. In. South Africa, the national vaccine initiative is considering the future conduct of trials ...

  11. 77 FR 40400 - National Women's Business Council

    Science.gov (United States)

    2012-07-09

    ... SMALL BUSINESS ADMINISTRATION National Women's Business Council AGENCY: U.S. Small Business... Business Council (NWBC). The meeting will be open to the public. DATES: The meeting will be held on July 17... Business Council. The National Women's Business Council is tasked with providing policy recommendations on...

  12. 77 FR 42297 - National Petroleum Council

    Science.gov (United States)

    2012-07-18

    ... DEPARTMENT OF ENERGY National Petroleum Council AGENCY: Department of Energy, Office of Fossil... National Petroleum Council. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that... Matters Discussion of Any Other Business Properly Brought Before the National Petroleum Council...

  13. 76 FR 53889 - National Petroleum Council

    Science.gov (United States)

    2011-08-30

    ... DEPARTMENT OF ENERGY National Petroleum Council AGENCY: Department of Energy, Office of Fossil... Petroleum Council. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public... Properly Brought Before the National, Petroleum Council, Adjournment. Public Participation: The meeting is...

  14. European Research Council supports an extensive study of the astrophysical p-process

    International Nuclear Information System (INIS)

    Gyuerky, Gy.

    2008-01-01

    Complete text of publication follows. The astrophysical p-process, the production mechanism of the heavy proton rich isotopes (the so-called p-nuclei) is still one of the least understood processes of nucleosynthesis. The modeling of the process requires a huge network of thousands of reactions where the rates of the involved reactions represent one of the biggest uncertainty in the resulting abundances of p-nuclei. In lack of experimental data the required reaction rates are taken from statistical model calculations which proved to be inaccurate in the mass and energy range relevant for the p-process. The systematic experimental study of the relevant reactions is therefore crucial to test the calculated reaction rates, to select the best input parameters for the calculations and, consequently, to contribute to a better understanding of the astrophysical p-process. The European Research Council (ERC) has acknowledged this need for experimental data when they decided to support a project devoted to this subject. In 2007 the first call of the ERC Frontier Research Scheme (Starting Grants) has been launched within the FP7 Specific Programme 'IDEAS'. From the very high number of applications, the peer reviewers of the ERC Scientific Council has recommended for funding the proposal entitled 'Nuclear reaction studies relevant to the astrophysical p-process nucleosynthesis'. An amount of 750,000 Euro has been allocated to the project for a 5 year duration. The starting date of the project was 1st July, 2008. With the ERC support, an extensive experimental study of the p-process is being carried out. The experiments will be carried out almost exclusively with the accelerators of the ATOMKI. The financial support allows to largely improve the available experimental technique. The purchase of two large volume HPGe detectors is in progress as a result of a public procurement. The upgrade of the nuclear electronics and data acquisition system used for p-process related

  15. 78 FR 45580 - Hispanic Council on Federal Employment

    Science.gov (United States)

    2013-07-29

    ... OFFICE OF PERSONNEL MANAGEMENT Hispanic Council on Federal Employment AGENCY: Office of Personnel Management. ACTION: Cancelling and re-scheduling of Council meetings. SUMMARY: The Hispanic Council on Federal Employment (Council) is cancelling the August 29, 2013 Council meeting and will hold its remaining...

  16. 78 FR 65010 - Hispanic Council on Federal Employment

    Science.gov (United States)

    2013-10-30

    ... OFFICE OF PERSONNEL MANAGEMENT Hispanic Council on Federal Employment AGENCY: Office of Personnel Management. ACTION: Cancelling and Re-Scheduling of Council Meetings. SUMMARY: The Hispanic Council on Federal Employment (Council) is cancelling the October 31, 2013 Council meeting and will hold its...

  17. Biased and inadequate citation of prior research in reports of cardiovascular trials is a continuing source of waste in research.

    Science.gov (United States)

    Sawin, Veronica I; Robinson, Karen A

    2016-01-01

    We assessed citation of prior research over time and the association of citation with the agreement of results between the trial being reported and the prior trial. Groups of pharmacologic trials in cardiovascular disease were created using meta-analyses, and we assessed citation within these groups. We calculated the proportion of prior trials cited, the proportion of study participants captured in citations, and agreement of results between citing and cited trials. Analysis included 86 meta-analyses with 580 trials published between 1982 and 2011. Reports of trials cited 25% (median; 95% confidence interval [CI], 23-27%) of prior trials, capturing 31% (95% CI, 25-36%) of trial participants. Neither measure differed by publication of the citing trial before vs. after 2005. Prior trials with results that agreed with the reports of trials (supportive trials) were significantly more likely to be cited than nonsupportive trials (relative risk 1.45; 95% CI, 1.30-1.61, P < 0.001). Selective undercitation of prior research continues; three quarters of existing evidence is ignored. This source of waste may result in unnecessary, unethical, and unscientific studies. Copyright © 2016 Elsevier Inc. All rights reserved.

  18. 75 FR 20832 - National Coal Council

    Science.gov (United States)

    2010-04-21

    ... DEPARTMENT OF ENERGY National Coal Council AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the National Coal Council (NCC). The Federal Advisory... Biomass/Coal Blending to Generate Electricity Council Business: [cir] Finance Report by Committee Chairman...

  19. 78 FR 40131 - National Petroleum Council

    Science.gov (United States)

    2013-07-03

    ... DEPARTMENT OF ENERGY National Petroleum Council AGENCY: Office of Fossil Energy, Department of... Petroleum Council. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public... Administrative Matters Discussion of Any Other Business Properly Brought Before the National Petroleum Council...

  20. Does a research article's country of origin affect perception of its quality and relevance? A national trial of US public health researchers.

    Science.gov (United States)

    Harris, M; Macinko, J; Jimenez, G; Mahfoud, M; Anderson, C

    2015-12-30

    The source of research may influence one's interpretation of it in either negative or positive ways, however, there are no robust experiments to determine how source impacts on one's judgment of the research article. We determine the impact of source on respondents' assessment of the quality and relevance of selected research abstracts. Web-based survey design using four healthcare research abstracts previously published and included in Cochrane Reviews. All Council on the Education of Public Health-accredited Schools and Programmes of Public Health in the USA. 899 core faculty members (full, associate and assistant professors) Each of the four abstracts appeared with a high-income source half of the time, and low-income source half of the time. Participants each reviewed the same four abstracts, but were randomly allocated to receive two abstracts with high-income source, and two abstracts with low-income source, allowing for within-abstract comparison of quality and relevance Within-abstract comparison of participants' rating scores on two measures--strength of the evidence, and likelihood of referral to a peer (1-10 rating scale). OR was calculated using a generalised ordered logit model adjusting for sociodemographic covariates. Participants who received high income country source abstracts were equal in all known characteristics to the participants who received the abstracts with low income country sources. For one of the four abstracts (a randomised, controlled trial of a pharmaceutical intervention), likelihood of referral to a peer was greater if the source was a high income country (OR 1.28, 1.02 to 1.62, pincome source in their rating of research abstracts. More research may be needed to explore how the origin of a research article may lead to stereotype activation and application in research evaluation. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  1. Maximising the impact of qualitative research in feasibility studies for randomised controlled trials: guidance for researchers

    NARCIS (Netherlands)

    O’Cathain, A.; Hoddinott, P.; Lewin, S.; Thomas, K.J.; Young, B.; Adamson, J.; Jansen, J.F.M.; Mills, N.; Moore, G.; Donovan, J.L.

    2015-01-01

    Feasibility studies are increasingly undertaken in preparation for randomised controlled trials in order to explore uncertainties and enable trialists to optimise the intervention or the conduct of the trial. Qualitative research can be used to examine and address key uncertainties prior to a full

  2. A ten-year history: the Cancer Quality Council of Ontario.

    Science.gov (United States)

    Anas, Rebecca; Bell, Robert; Brown, Adalsteinn; Evans, William; Sawka, Carol

    2012-01-01

    One of the longest-established quality oversight organizations in Canadian healthcare, the Cancer Quality Council of Ontario (CQCO) is an advisory group formed in 2002 by the Ministry of Health and Long-Term Care. Although quasi-independent from Cancer Care Ontario (CCO), the council was established to provide advice to CCO and the ministry in their efforts to improve the quality of cancer care in the province. The council is composed of a multidisciplinary group of healthcare providers, cancer survivors and experts in the areas of oncology, health system policy and administration, governance, performance measurement and health services research. Its mandate is to monitor and report publicly on the performance of the Ontario cancer system and to motivate improvement through national and international benchmarking. Since its formation, the council has played an evolving role in improving the quality of care received by Ontario cancer patients. This article will briefly describe the origins and founding principles of the CQCO, its changing role in monitoring quality and its relationship with CCO. Copyright © 2012 Longwoods Publishing.

  3. A Linguistic Analysis of the Sample Numeracy Skills Test Items for Pre-Service Teachers Issued by the Australian Council for Educational Research (ACER)

    Science.gov (United States)

    O'Keeffe, Lisa; O'Halloran, Kay L.; Wignell, Peter; Tan, Sabine

    2017-01-01

    In 2015, the Australian Council for Educational Research (ACER) was tasked with developing literacy and numeracy skills testing for pre-service teachers. All undergraduate and postgraduate trainee teachers are now required to pass these literacy and numeracy tests at some stage on their journey to becoming a teacher; for commencing students from…

  4. 78 FR 12107 - Hispanic Council on Federal Employment

    Science.gov (United States)

    2013-02-21

    ... OFFICE OF PERSONNEL MANAGEMENT Hispanic Council on Federal Employment AGENCY: Office of Personnel Management. ACTION: Scheduling of Council Meetings. SUMMARY: The Hispanic Council on Federal Employment will hold its 2013 Council meetings on the dates and location shown below. The Council is an advisory...

  5. 76 FR 45516 - Gulf of Mexico Fishery Management Council (Council); Public Meetings

    Science.gov (United States)

    2011-07-29

    ... meeting will be held August 15-19, 2011. ADDRESSES: The meeting will be held at the Crowne Plaza Hotel... Collection; Budget/Personnel; and Administrative Policy. 12:30 p.m.-4:30 p.m.--The Council will receive... Panels. 9 a.m.-9:30 a.m.--Closed Session--The Budget/Personnel Committee/ Full Council will meet to...

  6. 77 FR 52067 - NASA Advisory Council; Commercial Space Committee; Meeting

    Science.gov (United States)

    2012-08-28

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [12-069] NASA Advisory Council; Commercial Space.... DATES: Tuesday, September 18, 2012, 11:45 a.m.-5:30 p.m.; Local Time. ADDRESSES: NASA Ames Research Center (ARC), The Showroom, Building M-3, NASA Ames Conference Center, 500 Severyns Road, NASA Research...

  7. Shedding light on research participation effects in behaviour change trials: a qualitative study examining research participant experiences

    Directory of Open Access Journals (Sweden)

    Virginia MacNeill

    2016-01-01

    Full Text Available Abstract Background The sequence of events in a behaviour change trial involves interactions between research participants and the trial process. Taking part in such a study has the potential to influence the behaviour of the participant, and if it does, this can engender bias in trial outcomes. Since participants’ experience has received scant attention, the aim of this study is thus to generate hypotheses about which aspects of the conduct of behaviour change trials might matter most to participants, and thus have potential to alter subsequent behaviours and bias trial outcomes Methods Twenty participants were opportunistically screened for a health compromising behaviour (unhealthy diet, lack of exercise, smoking or alcohol consumption and recruited if eligible. Semi structured face to face interviews were conducted, after going through the usual processes involved in trial recruitment, baseline assessment and randomisation. Participants were given information on the contents of an intervention or control condition in a behaviour change trial, which was not actually implemented. Three months later they returned to reflect on these experiences and whether they had any effect on their behaviour during the intervening period. Data from the latter interview were analysed thematically using a modified grounded theory approach. Results The early processes of trial participation raised awareness of unhealthy behaviours, although most reported having had only fleeting intentions to change their behaviour as a result of taking part in this study, in the absence of interventions. However, careful examination of the accounts revealed evidence of subtle research participation effects, which varied according to the health behaviour, and its perceived social acceptability. Participants’ relationships with the research study were viewed as somewhat important in stimulating thinking about whether and how to make lifestyle changes. Conclusion These

  8. Developing a clinical trial unit to advance research in an academic institution.

    Science.gov (United States)

    Croghan, Ivana T; Viker, Steven D; Limper, Andrew H; Evans, Tamara K; Cornell, Alissa R; Ebbert, Jon O; Gertz, Morie A

    2015-11-01

    Research, clinical care, and education are the three cornerstones of academic health centers in the United States. The research climate has always been riddled with ebbs and flows, depending on funding availability. During a time of reduced funding, the number and scope of research studies have been reduced, and in some instances, a field of study has been eliminated. Recent reductions in the research funding landscape have led institutions to explore new ways to continue supporting research. Mayo Clinic in Rochester, MN has developed a clinical trial unit within the Department of Medicine, which provides shared resources for many researchers and serves as a solution for training and mentoring new investigators and study teams. By building on existing infrastructure and providing supplemental resources to existing research, the Department of Medicine clinical trial unit has evolved into an effective mechanism for conducting research. This article discusses the creation of a central unit to provide research support in clinical trials and presents the advantages, disadvantages, and required building blocks for such a unit. Copyright © 2015 Mayo Clinic. Published by Elsevier Inc. All rights reserved.

  9. The UK clinical research network - has it been a success for dermatology clinical trials?

    Directory of Open Access Journals (Sweden)

    Charlesworth Lisa

    2011-06-01

    Full Text Available Abstract Background Following the successful introduction of five topic-specific research networks in the UK, the Comprehensive Local Research Network (CLRN was established in 2008 in order to provide a blanket level of support across the whole country regardless of the clinical discipline. The role of the CLRN was to facilitate recruitment into clinical trials, and to encourage greater engagement in research throughout the National Health Service (NHS. Methods This report evaluates the impact of clinical research networks in supporting clinical trials in the UK, with particular reference to our experiences from two non-commercial dermatology trials. It covers our experience of engaging with the CLRN (and other research networks using two non-commercial dermatology trials as case studies. We present the circumstances that led to our approach to the research networks for support, and the impact that this support had on the delivery of these trials. Results In both cases, recruitment was boosted considerably following the provision of additional support, although other factors such as the availability of experienced personnel, and the role of advertising and media coverage in promoting the trials were also important in translating this additional resource into increased recruitment. Conclusions Recruitment into clinical trials is a complex task that can be influenced by many factors. A world-class clinical research infrastructure is now in place in England (with similar support available in Scotland and Wales, and it is the responsibility of the research community to ensure that this unique resource is used effectively and responsibly.

  10. 76 FR 74049 - National Coal Council

    Science.gov (United States)

    2011-11-30

    ... DEPARTMENT OF ENERGY National Coal Council AGENCY: Office of Fossil Energy, Department of Energy..., notice is hereby given that the National Coal Council will be renewed for a two-year period beginning... general policy matters relating to coal issues. Additionally, the renewal of the Council has been...

  11. 78 FR 7424 - National Coal Council

    Science.gov (United States)

    2013-02-01

    ... DEPARTMENT OF ENERGY National Coal Council AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the National Coal Council (NCC). The Federal Advisory... 2013 meeting of the National Coal Council. Agenda: 1. Opening Remarks by NCC Chairman John Eaves 2...

  12. 78 FR 23242 - National Coal Council

    Science.gov (United States)

    2013-04-18

    ... DEPARTMENT OF ENERGY National Coal Council AGENCY: Department of Energy. ACTION: Notice of open meetings. SUMMARY: This notice announces two meetings of the National Coal Council (NCC). The Federal...: Agenda for Thursday, May 16, 2013 1. Call to Order by John Eaves, Chairman, National Coal Council 2...

  13. Notification of upcoming AGU Council meeting

    Science.gov (United States)

    Williams, Billy

    2012-10-01

    The AGU Council will meet on Sunday, 2 December 2012, at the InterContinental Hotel in San Francisco, Calif. The meeting, which is open to all AGU members, will include discussions of AGU's new Grand Challenge Project (a project that will be introduced to members at the 2012 Fall Meeting), the proposed AGU scientific ethics policy, publishing strategies, future plans for honors and recognition, and leadership transition as new members join the Council. This year the Council experimented with a new approach to conducting business. By holding virtual meetings throughout the year, Council members have been able to act in a more timely manner and provide input on important membership and science issues on the Board of Directors' agenda. The Council Leadership Team—an elected subset of the Council—also experimented with a new approach, meeting every month to keep moving projects forward. This approach has increased communication and improved effectiveness in Council decision making.

  14. [The participation in health councils and its interface with politics culture].

    Science.gov (United States)

    de Oliveira, Lucia Conde; Pinheiro, Roseni

    2010-08-01

    The objective of this paper is to analyse the participation of current health councils in a city in the north-eastern of Brazil and its relationship with local political culture. The following theoretical presumption served as starting point: The practices adopted by health councils initiate a new institution that involves new social actors - the users - in the public sphere. The process of democratisation in the Brazilian society expands this sphere and leads to a confrontation of traditional and democratic political cultures. This is a qualitative research with the following data collection methods: documentary analysis, participant observation and semi-structured interviews. Within the evidence emerged, the dominance of traditional political culture resulted as one of the conditioning elements of participation practices in the Council, expressed in the authoritarianism and cooptation involving municipal managers and representatives of civil society. The majority of counsellors recognises the fragile power of the Council in terms of deliberative and fiscal issues. Despite confirming the frailties of the health councils, it is obvious that their importance in the democratisation of the relationship between State and civil society in the fight for the implementation of the right to health care.

  15. Clinical Trial Design for HIV Prevention Research: Determining Standards of Prevention.

    Science.gov (United States)

    Dawson, Liza; Zwerski, Sheryl

    2015-06-01

    This article seeks to advance ethical dialogue on choosing standards of prevention in clinical trials testing improved biomedical prevention methods for HIV. The stakes in this area of research are high, given the continued high rates of infection in many countries and the budget limitations that have constrained efforts to expand treatment for all who are currently HIV-infected. New prevention methods are still needed; at the same time, some existing prevention and treatment interventions have been proven effective but are not yet widely available in the countries where they most urgently needed. The ethical tensions in this field of clinical research are well known and have been the subject of extensive debate. There is no single clinical trial design that can optimize all the ethically important goals and commitments involved in research. Several recent articles have described the current ethical difficulties in designing HIV prevention trials, especially in resource limited settings; however, there is no consensus on how to handle clinical trial design decisions, and existing international ethical guidelines offer conflicting advice. This article acknowledges these deep ethical dilemmas and moves beyond a simple descriptive approach to advance an organized method for considering what clinical trial designs will be ethically acceptable for HIV prevention trials, balancing the relevant criteria and providing justification for specific design decisions. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.

  16. 36 CFR 801.4 - Council comments.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Council comments. 801.4 Section 801.4 Parks, Forests, and Public Property ADVISORY COUNCIL ON HISTORIC PRESERVATION HISTORIC PRESERVATION REQUIREMENTS OF THE URBAN DEVELOPMENT ACTION GRANT PROGRAM § 801.4 Council comments. The following...

  17. 78 FR 71592 - National Coal Council

    Science.gov (United States)

    2013-11-29

    ... DEPARTMENT OF ENERGY National Coal Council AGENCY: Department of Energy, Office of Fossil Energy..., notice is hereby given that the National Coal Council (NCC) will be renewed for a two-year period. The... matters relating to coal issues. Additionally, the renewal of the National Coal Council has been...

  18. Parent-School Councils in Beijing, China

    Science.gov (United States)

    Lewis, Wayne D.; Bjork, Lars G.; Zhao, Yuru; Chi, Bin

    2011-01-01

    This exploratory study examines how schools in Beijing have responded to a Chinese national policy mandate to establish and maintain parent councils. We surveyed principals and parent council members across schools in the Beijing municipality about the establishment and functions of their schools' parent councils. Survey results provide insights…

  19. Council | About IASc | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Council. The affairs and property of the Academy are administered by a Council of 20, consisting of a President, four Vice-Presidents, a Treasurer, two Secretaries, and twelve other members. The Council, with a term of three years, is elected by the Fellows triennially. Members of the Council for the period 2016 to 2018:.

  20. Governance systems in family SMEs: the substitution effects between family councils and corporate governance mechanisms

    OpenAIRE

    L. Gnan; D. Montemerlo; M. Huse

    2015-01-01

    The main objective of this paper is to explore the role of family councils vis-à-vis corporate governance mechanisms. Particularly, the paper explores whether family councils perform only their distinctive family governance role or if they also substitute for the roles performed by corporate governance control mechanisms. Based on a sample of 243 Italian family SMEs, our research findings show that the family council partially substitutes the shareholders' meeting and the board of directors i...

  1. Undergraduate Research as a Primary Pathway to STEM Careers: Perspectives from the Council on Undergraduate Research

    Science.gov (United States)

    Manley, P. L.; Ambos, E. L.

    2012-12-01

    Undergraduate research (UR) is one of the most authentic and effective ways to promote student learning, and is a high-impact educational practice that can lead to measurable gains in student retention and graduation rates, as well as career aspirations. In recent years, UR has expanded from intensive summer one-on-one faculty-student mentored experiences to application in a variety of educational settings, including large lower division courses. The Council on Undergraduate Research (CUR), founded in 1978, is a national organization of individual (8000) and institutional members (650) within a divisional structure that includes geosciences, as well as 10 other thematic areas. CUR's main mission is to support and promote high-quality undergraduate student-faculty collaborative research and scholarship that develops learning through research. CUR fulfills this mission through extensive publication offerings, faculty and student-directed professional development events, and outreach and advocacy activities that share successful models and strategies for establishing, institutionalizing, and sustaining undergraduate research programs. Over the last decade, CUR has worked with hundreds of academic institutions, including two-year colleges, to develop practices to build undergraduate research into campus cultures and operations. As documented in CUR publications such as Characteristics of Excellence in Undergraduate Research (COEUR), strategies institutions may adopt to enhance and sustain UR often include: (1) the establishment of a central UR campus office, (2) extensive student and faculty participation in campus-based, as well as regional UR celebration events, (3) development of a consistent practice of assessment of UR's impact on student success, and, (4) establishment of clear policies for recognizing and rewarding faculty engagement in UR, particularly with respect to mentorship and publication with student scholars. Three areas of current focus within the

  2. Advocacy for active transport: advocate and city council perspectives

    Directory of Open Access Journals (Sweden)

    Rosenby Marieah

    2010-01-01

    Full Text Available Abstract Background Effective advocacy is an important part of efforts to increase population participation in physical activity. Research about effective health advocacy is scarce, however, the health sector can learn from the experiences and knowledge of community advocates and those who are on the receiving end of this advocacy. The aim of this study is to explore advocacy for active transport from the perspectives of community advocates and representatives from City councils. Methods Cycling and walking advocates were identified from the local contact list of Cycling Advocates Network and Living Streets Aotearoa. Semi-structured telephone interviews were conducted with cycle and walking advocates from throughout New Zealand. Advocates also nominated a suitable council officer at their local City council to be interviewed. Interviews were recorded and transcribed and categories of responses for each of the questions created. Results Several processes were used by advocates to engage with council staff, including formal council submissions, meetings, stakeholder forums and partnership in running community events promoting active transport. Several other agencies were identified as being influential for active transport, some as potential coalition partners and others as potential adversaries. Barriers to improving conditions for active transport included a lack of funding, a lack of will-power among either council staff or councillors, limited council staff capacity (time or training and a culture of providing infrastructure for motor vehicles instead of people. Several suggestions were made about how the health sector could contribute to advocacy efforts, including encouraging political commitment, engaging the media, communicating the potential health benefits of active transport to the general public and being role models in terms of personal travel mode choice and having workplaces that support participation in active transport

  3. The Council of Academic Hospitals of Ontario (CAHO) Adopting Research to Improve Care (ARTIC) Program: Reach, Sustainability, Spread and Lessons Learned from an Implementation Funding Model

    OpenAIRE

    Moore, Julia E.; Grouchy, Michelle; Graham, Ian D.; Shandling, Maureen; Doyle, Winnie; Straus, Sharon E.

    2016-01-01

    Despite evidence on what works in healthcare, there is a significant gap in the time it takes to bring research into practice. The Council of Academic Hospitals of Ontario's Adopting Research to Improve Care program addresses this research-to-practice gap by incorporating the following components into its funding program: strategic selection of evidence for implementation, education and training for implementation, implementation supports, executive champions and governance, and evaluation. F...

  4. The trials methodological research agenda: results from a priority setting exercise

    Science.gov (United States)

    2014-01-01

    Background Research into the methods used in the design, conduct, analysis, and reporting of clinical trials is essential to ensure that effective methods are available and that clinical decisions made using results from trials are based on the best available evidence, which is reliable and robust. Methods An on-line Delphi survey of 48 UK Clinical Research Collaboration registered Clinical Trials Units (CTUs) was undertaken. During round one, CTU Directors were asked to identify important topics that require methodological research. During round two, their opinion about the level of importance of each topic was recorded, and during round three, they were asked to review the group’s average opinion and revise their previous opinion if appropriate. Direct reminders were sent to maximise the number of responses at each round. Results are summarised using descriptive methods. Results Forty one (85%) CTU Directors responded to at least one round of the Delphi process: 25 (52%) responded in round one, 32 (67%) responded in round two, 24 (50%) responded in round three. There were only 12 (25%) who responded to all three rounds and 18 (38%) who responded to both rounds two and three. Consensus was achieved amongst CTU Directors that the top three priorities for trials methodological research were ‘Research into methods to boost recruitment in trials’ (considered the highest priority), ‘Methods to minimise attrition’ and ‘Choosing appropriate outcomes to measure’. Fifty other topics were included in the list of priorities and consensus was reached that two topics, ‘Radiotherapy study designs’ and ‘Low carbon trials’, were not priorities. Conclusions This priority setting exercise has identified the research topics felt to be most important to the key stakeholder group of Directors of UKCRC registered CTUs. The use of robust methodology to identify these priorities will help ensure that this work informs the trials methodological research agenda, with

  5. Elections to Staff Council

    CERN Multimedia

    Staff Association

    2011-01-01

    Elections to fill all seats in the Staff Council are being organized this month. The voting takes place from the 31st of October to the 14th of November, at noon. As you may have noted when reading Echo, many issues concerning our employment conditions are on the agenda of the coming months and will keep the next Staff Council very busy. So, make your voice heard and take part in the elections for a new Staff Council. By doing so, you will be encouraging the men and women who will be representing you over the next two years and they will doubtless appreciate your gratitude. Every member of the Staff Association will have received an email containing a link to the webpage which will allow voting. If you are a member of the Staff Association and you did not receive such an email, please contact the Staff Association secretariat (staff.association@cern.ch). Do not forget to vote * * * * * * * Vote Make your voice heard and be many to elect the new Staff Council. More details on the election...

  6. Digital pathology in nephrology clinical trials, research, and pathology practice.

    Science.gov (United States)

    Barisoni, Laura; Hodgin, Jeffrey B

    2017-11-01

    In this review, we will discuss (i) how the recent advancements in digital technology and computational engineering are currently applied to nephropathology in the setting of clinical research, trials, and practice; (ii) the benefits of the new digital environment; (iii) how recognizing its challenges provides opportunities for transformation; and (iv) nephropathology in the upcoming era of kidney precision and predictive medicine. Recent studies highlighted how new standardized protocols facilitate the harmonization of digital pathology database infrastructure and morphologic, morphometric, and computer-aided quantitative analyses. Digital pathology enables robust protocols for clinical trials and research, with the potential to identify previously underused or unrecognized clinically useful parameters. The integration of digital pathology with molecular signatures is leading the way to establishing clinically relevant morpho-omic taxonomies of renal diseases. The introduction of digital pathology in clinical research and trials, and the progressive implementation of the modern software ecosystem, opens opportunities for the development of new predictive diagnostic paradigms and computer-aided algorithms, transforming the practice of renal disease into a modern computational science.

  7. More ethical and more efficient clinical research: multiplex trial design.

    Science.gov (United States)

    Keus, Frederik; van der Horst, Iwan C C; Nijsten, Maarten W

    2014-08-14

    Today's clinical research faces challenges such as a lack of clinical equipoise between treatment arms, reluctance in randomizing for multiple treatments simultaneously, inability to address interactions and increasingly restricted resources. Furthermore, many trials are biased by extensive exclusion criteria, relatively small sample size and less appropriate outcome measures. We propose a 'Multiplex' trial design that preserves clinical equipoise with a continuous and factorial trial design that will also result in more efficient use of resources. This multiplex design accommodates subtrials with appropriate choice of treatment arms within each subtrial. Clinical equipoise should increase consent rates while the factorial design is the best way to identify interactions. The multiplex design may evolve naturally from today's research limitations and challenges, while principal objections seem absent. However this new design poses important infrastructural, organisational and psychological challenges that need in depth consideration.

  8. 18 CFR 701.76 - The Water Resources Council Staff.

    Science.gov (United States)

    2010-04-01

    ... Council Staff. 701.76 Section 701.76 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Headquarters Organization § 701.76 The Water Resources Council Staff. The Water Resources Council Staff (hereinafter the Staff) serves the Council and the Chairman in the performance of...

  9. News and Views: Research council resource allocations: managing demand; e-MERLIN radio telescope network is up and running

    Science.gov (United States)

    2011-02-01

    The research councils discovered in December the allocation of money from the UK government's Comprehensive Spending Review, and have set out their delivery plans outlining how they will spend it. Details and decisions will follow consultation in the coming months. The first image from eMerlin, the UK's national radio astronomy facility, shows the power of the enhanced network of radio telescopes spread over 220 km and now linked by fibre optics. These links and advanced receivers will allow astronomers to see in a single day what would have previously taken them more than a year of observations.

  10. DECLARATION TO COUNCIL

    CERN Multimedia

    Staff Association

    2015-01-01

    One year ago, the Staff Association, together with the CERN-ESO Pensioners' Association, organized a staff meeting in front of this building to express our concern about certain actions of this Committee. Today we deem it necessary to come before you and convey in person, dear delegates, the concerns and worries of the staff. Indeed, the last 18 months we have observed a tendency of Council to take matters, in particular in the field of pensions, into its own hands, bypassing established governance structures, which Council has itself put into place. As a result, the Director General was prevented from playing his essential role of intermediary between staff and Council, an essential element of the established social dialogue. The creation of CERN in 1954 was very much based on the willingness of many countries of the old Continent to share resources to create a joint fundamental physics laboratory. The emphasis was on sharing resources for the common good to allow European scientists to engage in...

  11. Uganda gets set for vaccine trials, but the ethical debate continues.

    Science.gov (United States)

    1997-04-01

    An HIV vaccine trial scheduled for 1997 involves 2000 male and female members of the Uganda People's Defence Force. The volunteers are 18-40 years old and have been evaluated for 18 months. The trial of Alvac-HIV vaccine developed by Pasteur Manieux Connaught will be conducted by the Joint Clinical Research Council, a joint venture of Makerere University and the Ministries of Health and Defence, in collaboration with the Johns Hopkins University. The vaccine has already been tested on 300 volunteers in France and the US. The initial stage of testing will involve a randomized, placebo-controlled, double-blind trial comparing the safety and immunogenicity of four successive injections in 20 HIV-negative and 20 HIV-positive volunteers. Follow-up will continue for a year. While volunteers will get free medical attention if they develop a severe reaction to the vaccine and will receive a full explanation about the experimental nature of the vaccine, it has not been determined how volunteers will be compensated if something unforeseen goes wrong. Additional concerns revolve around Uganda's readiness to institute proper legal controls and ethical standards in cases of biomedical research.

  12. 77 FR 2275 - Manufacturing Council

    Science.gov (United States)

    2012-01-17

    ... DEPARTMENT OF COMMERCE International Trade Administration Manufacturing Council AGENCY... candidate's proven experience in promoting, developing and marketing programs in support of manufacturing... participating in Council meetings and events are responsible for their travel, living and other personal...

  13. 78 FR 54257 - Advisory Council on Blood Stem Cell Transplantation; Request for Nominations for Voting Members

    Science.gov (United States)

    2013-09-03

    ...; Program priorities; research priorities; and the scope and design of the Stem Cell Therapeutic Outcomes... Council on Blood Stem Cell Transplantation; Request for Nominations for Voting Members AGENCY: Health... on the Advisory Council on Blood Stem Cell Transplantation (ACBSCT). The ACBSCT was established...

  14. 76 FR 11491 - Advisory Council on Blood Stem Cell Transplantation; Request for Nominations for Voting Members

    Science.gov (United States)

    2011-03-02

    ... transplantation, Program priorities, research priorities, and the scope and design of the Stem Cell Therapeutic... Council on Blood Stem Cell Transplantation; Request for Nominations for Voting Members AGENCY: Health... on Blood Stem Cell Transplantation. The Advisory Council on Blood Stem Cell Transplantation was...

  15. 76 FR 33244 - Manufacturing Council

    Science.gov (United States)

    2011-06-08

    ... DEPARTMENT OF COMMERCE International Trade Administration Manufacturing Council AGENCY... experience in promoting, developing and marketing programs in support of manufacturing industries, in job... Council meetings and events are responsible for their travel, living and other personal expenses. Meetings...

  16. Setting the pace: the 2011 Australasian Podiatry Council conference

    Science.gov (United States)

    2011-01-01

    The 2011 Australasian Podiatry Council conference was held from April 26 to 29 in Melbourne, Victoria, Australia. This commentary provides a brief overview of the conference, including the speakers and topic areas covered, selected original research highlights, and award winning presentations. PMID:21762520

  17. 76 FR 16643 - NASA Advisory Council; Aeronautics Committee; Meeting

    Science.gov (United States)

    2011-03-24

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-024)] NASA Advisory Council; Aeronautics... Aeronautics and Space Administration announces a meeting of the Aeronautics Committee of the NASA Advisory.... ADDRESSES: Thursday, April 14, 2011--NASA Dryden Flight Research Center (DFRC), Lilly Drive Building 4825...

  18. 75 FR 41240 - NASA Advisory Council; Aeronautics Committee; Meeting

    Science.gov (United States)

    2010-07-15

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (10-079)] NASA Advisory Council; Aeronautics... Aeronautics and Space Administration announces a meeting of the Aeronautics Committee of the NASA Advisory....m. to 4 p.m. (local time). ADDRESSES: NASA Glenn Research Center, Building 15, Small Dining...

  19. ITER council proceedings: 1996

    International Nuclear Information System (INIS)

    1997-01-01

    Records of the 10. ITER Council Meeting (IC-10), held on 26-27 July 1996, in St. Petersburg, Russia, and the 11. ITER Council Meeting (IC-11) held on 17-18 December 1996, in Tokyo, Japan, are presented, giving essential information on the evolution of the ITER Engineering Design Activities (EDA) and the cost review and safety analysis. Figs, tabs

  20. ITER council proceedings: 1995

    International Nuclear Information System (INIS)

    1996-01-01

    Records of the 8. ITER Council Meeting (IC-8), held on 26-27 July 1995, in San Diego, USA, and the 9. ITER Council Meeting (IC-9) held on 12-13 December 1995, in Garching, Germany, are presented, giving essential information on the evolution of the ITER Engineering Design Activities (EDA) and the ITER Interim Design Report Package and Relevant Documents. Figs, tabs

  1. 76 FR 55363 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2011-09-07

    ... Pacific Fishery Management Council's (Pacific Council) Groundfish Management Team (GMT) [[Page 55364... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National...; telephone: (206) 526-6150. Council address: Pacific Fishery Management Council, 7700 NE Ambassador Place...

  2. 77 FR 75614 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-12-21

    ... Pacific Fishery Management Council's (Pacific Council) Highly Migratory Species Management Team (HMSMT... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National.... Council address: Pacific Fishery Management Council, 7700 NE. Ambassador Place, Suite 101, Portland, OR...

  3. 75 FR 80470 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-12-22

    ... Pacific Fishery Management Council's (Council) Groundfish Management Team (GMT) will hold a working... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National.... Council address: Pacific Fishery Management Council, 7700 NE. Ambassador Place, Suite 101, Portland, OR...

  4. Simulation Performance and National Council Licensure Examination for Registered Nurses Outcomes: Field Research Perspectives.

    Science.gov (United States)

    Brackney, Dana E; Lane, Susan Hayes; Dawson, Tyia; Koontz, Angie

    2017-11-01

    This descriptive field study examines processes used to evaluate simulation for senior-level Bachelor of Science in Nursing (BSN) students in a capstone course, discusses challenges related to simulation evaluation, and reports the relationship between faculty evaluation of student performance and National Council Licensure Examination for Registered Nurses (NCLEX-RN) first-time passing rates. Researchers applied seven terms used to rank BSN student performance (n = 41, female, ages 22-24 years) in a senior-level capstone simulation. Faculty evaluation was correlated with students' NCLEX-RN outcomes. Students evaluated as "lacking confidence" and "flawed" were less likely to pass the NCLEX-RN on the first attempt. Faculty evaluation of capstone simulation performance provided additional evidence of student preparedness for practice in the RN role, as evidenced by the relationship between the faculty assessment and NCLEX-RN success. Simulation has been broadly accepted as a powerful educational tool that may also contribute to verification of student achievement of program outcomes and readiness for the RN role.

  5. 75 FR 81971 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-12-29

    ... Pacific Fishery Management Council's (Council) Highly Migratory Species Management Team (HMSMT) will hold... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National...., Carlsbad, CA 92011; telephone: (760) 431-9440. Council address: Pacific Fishery Management Council, 7700 NE...

  6. 77 FR 74469 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-12-14

    ... Pacific Fishery Management Council's (Pacific Council) Groundfish Management Team (GMT) will hold a week... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National...) 634-2000. Council address: Pacific Fishery Management Council, 7700 NE Ambassador Place, Suite 101...

  7. Turning Failure into Success: Trials of the Heart Failure Clinical Research Network.

    Science.gov (United States)

    Joyce, Emer; Givertz, Michael M

    2016-12-01

    The Heart Failure Clinical Research Network (HFN) was established in 2008 on behalf of the NIH National Heart, Lung and Blood Institute, with the primary goal of improving outcomes in heart failure (HF) by designing and conducting high-quality concurrent clinical trials testing interventions across the spectrum of HF. Completed HFN trials have answered several important and relevant clinical questions concerning the safety and efficacy of different decongestive and adjunctive vasodilator therapies in hospitalized acute HF, phosphodiesterase-5 inhibition and nitrate therapies in HF with preserved ejection fraction, and the role of xanthine oxidase inhibition in hyperuricemic HF. These successes, independent of the "positive" or "negative" result of each individual trial, have helped to shape the current clinical care of HF patients and serve as a platform to inform future research directions and trial designs.

  8. 77 FR 71200 - Hispanic Council on Federal Employment

    Science.gov (United States)

    2012-11-29

    ... OFFICE OF PERSONNEL MANAGEMENT Hispanic Council on Federal Employment AGENCY: Office of Personnel Management. ACTION: Scheduling of Council Meeting. SUMMARY: The Hispanic Council on Federal Employment (HCFE) will hold a meeting on Monday, December 13th, at the time and location shown below. The Council is an...

  9. Setting the pace: the 2011 Australasian Podiatry Council conference

    Directory of Open Access Journals (Sweden)

    Firth Julia

    2011-07-01

    Full Text Available Abstract The 2011 Australasian Podiatry Council conference was held from April 26 to 29 in Melbourne, Victoria, Australia. This commentary provides a brief overview of the conference, including the speakers and topic areas covered, selected original research highlights, and award winning presentations.

  10. 75 FR 17166 - NASA Advisory Council; Aeronautics Committee; Meeting

    Science.gov (United States)

    2010-04-05

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (10-038)] NASA Advisory Council; Aeronautics... Aeronautics and Space Administration announces a meeting of the Aeronautics Committee of the NASA Advisory... a.m. to 1 p.m.; Eastern Daylight Time. ADDRESSES: NASA Langley Research Center, Building 1219, Room...

  11. 3 CFR 101.4 - National Security Council.

    Science.gov (United States)

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false National Security Council. 101.4 Section 101.4... PROCEDURES ACT § 101.4 National Security Council. Freedom of Information regulations for the National Security Council appear at 32 CFR Ch. XXI. ...

  12. Governor's Council on Disabilities and Special Education

    Science.gov (United States)

    State Employees Governor's Council on Disabilities and Special Education DHSS State of Alaska Home ; Governor's Council on Disabilities and Special Education Page Content Untitled Document Patrick Reinhart : follow GCDSE to 40404 The Governor's Council on Disabilities & Special Education is pleased to award

  13. Reporting of clinical trials: a review of research funders' guidelines

    Directory of Open Access Journals (Sweden)

    Williamson Paula R

    2008-11-01

    Full Text Available Abstract Background Randomised controlled trials (RCTs represent the gold standard methodological design to evaluate the effectiveness of an intervention in humans but they are subject to bias, including study publication bias and outcome reporting bias. National and international organisations and charities give recommendations for good research practice in relation to RCTs but to date no review of these guidelines has been undertaken with respect to reporting bias. Methods National and international organisations and UK based charities listed on the Association for Medical Research Charities website were contacted in 2007; they were considered eligible for this review if they funded RCTs. Guidelines were obtained and assessed in relation to what was written about trial registration, protocol adherence and trial publication. It was also noted whether any monitoring against these guidelines was undertaken. This information was necessary to discover how much guidance researchers are given on the publication of results, in order to prevent study publication bias and outcome reporting bias. Results Seventeen organisations and 56 charities were eligible of 140 surveyed for this review, although there was no response from 12. Trial registration, protocol adherence, trial publication and monitoring against the guidelines were often explicitly discussed or implicitly referred too. However, only eleven of these organisations or charities mentioned the publication of negative as well as positive outcomes and just three of the organisations specifically stated that the statistical analysis plan should be strictly adhered to and all changes should be reported. Conclusion Our review indicates that there is a need to provide more detailed guidance for those conducting and reporting clinical trials to help prevent the selective reporting of results. Statements found in the guidelines generally refer to publication bias rather than outcome reporting bias

  14. 77 FR 61626 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2012-10-10

    ...-FVWF97920900000-XXX] Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife Service, Interior... meeting of the Sport Fishing and Boating Partnership Council (Council). A Federal advisory committee, the... Sport Fishing and Boating Partnership Council will hold a meeting. Background The Council was formed in...

  15. Reducing Disparities in Cancer Screening and Prevention through Community-Based Participatory Research Partnerships with Local Libraries: A Comprehensive Dynamic Trial.

    Science.gov (United States)

    Rapkin, Bruce D; Weiss, Elisa; Lounsbury, David; Michel, Tamara; Gordon, Alexis; Erb-Downward, Jennifer; Sabino-Laughlin, Eilleen; Carpenter, Alison; Schwartz, Carolyn E; Bulone, Linda; Kemeny, Margaret

    2017-09-01

    Reduction of cancer-related disparities requires strategies that link medically underserved communities to preventive care. In this community-based participatory research project, a public library system brought together stakeholders to plan and undertake programs to address cancer screening and risk behavior. This study was implemented over 48 months in 20 large urban neighborhoods, selected to reach diverse communities disconnected from care. In each neighborhood, Cancer Action Councils were organized to conduct a comprehensive dynamic trial, an iterative process of program planning, implementation and evaluation. This process was phased into neighborhoods in random, stepped-wedge sequence. Population-level outcomes included self-reported screening adherence and smoking cessation, based on street intercept interviews. Event-history regressions (n = 9374) demonstrated that adherence outcomes were associated with program implementation, as were mediators such as awareness of screening programs and cancer information seeking. Findings varied by ethnicity, and were strongest among respondents born outside the U.S. or least engaged in care. This intervention impacted health behavior in diverse, underserved and vulnerable neighborhoods. It has been sustained as a routine library system program for several years after conclusion of grant support. In sum, participatory research with the public library system offers a flexible, scalable approach to reduce cancer health disparities. © Society for Community Research and Action 2017.

  16. Addiction research centres and the nurturing of creativity: The Alcohol & Drug Abuse Research Unit at the South African Medical Research Council - strengthening substance abuse research and policy in South Africa.

    Science.gov (United States)

    Parry, Charles; Morojele, Neo; Myers, Bronwyn; Plüddemann, Andreas

    2013-01-01

    The Alcohol and Drug Abuse Research Unit (ADARU) was established at the South African Medical Research Council (MRC) at the beginning of 2001, although its origins lie in the activities of the Centre for Epidemiological Research in Southern Africa and other MRC entities. Initial challenges included attracting external funding, recruiting new staff, developing the skills of junior staff, publishing in international journals and building national and international collaborative networks. ADARU currently comprises a core staff of 33 members who work on 22 projects spanning substance use epidemiology and associated consequences, intervention studies with at-risk populations and services research. A large component of this portfolio focuses on the link between alcohol and other drug use and human immunodeficiency virus (HIV) risk behaviour, with funding from the US Centers for Disease Control and Prevention. Junior staff members are encouraged to develop independent research interests and pursue PhD studies. Research outputs, such as the 20 papers that were published in 2010 and the 35 conference presentations from that year, form an important part of the unit's research translation activities. We engage actively with policy processes at the local, provincial, national and international levels, and have given particular attention to alcohol policy in recent years. The paper includes an analysis of major challenges currently facing the unit and how we are attempting to address them. It ends with some thoughts on what the unit intends doing to enhance the quality of its research, the capacity of its staff and its international standing. © 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.

  17. 78 FR 55114 - Native American Employment and Training Council (Council) Charter; Notice of Intent To Renew

    Science.gov (United States)

    2013-09-09

    ... equitable distribution of influence with the Council leadership; (3) opportunity for current members to take on more of a leadership role; (4) flexibility to maintain a healthy Council balance of experience and...

  18. Protocol for the mixed-methods process and context evaluation of the TB & Tobacco randomised controlled trial in Bangladesh and Pakistan: a hybrid effectiveness–implementation study

    Science.gov (United States)

    Nohavova, Iveta; Dogar, Omara; Kralikova, Eva; Pankova, Alexandra; Zvolska, Kamila; Huque, Rumana; Fatima, Razia; Noor, Maryam; Elsey, Helen; Sheikh, Aziz; Siddiqi, Kamran; Kotz, Daniel

    2018-01-01

    Introduction Tuberculosis (TB) remains a significant public health problem in South Asia. Tobacco use increases the risks of TB infection and TB progression. The TB& Tobacco placebo-controlled randomised trial aims to (1) assess the effectiveness of the tobacco cessation medication cytisine versus placebo when combined with behavioural support and (2) implement tobacco cessation medication and behavioural support as part of general TB care in Bangladesh and Pakistan. This paper summarises the process and context evaluation protocol embedded in the effectiveness–implementation hybrid design. Methods and analysis We are conducting a mixed-methods process and context evaluation informed by an intervention logic model that draws on the UK Medical Research Council’s Process Evaluation Guidance. Our approach includes quantitative and qualitative data collection on context, recruitment, reach, dose delivered, dose received and fidelity. Quantitative data include patient characteristics, reach of recruitment among eligible patients, routine trial data on dose delivered and dose received, and a COM-B (‘capability’, ‘opportunity’, ‘motivation’ and ‘behaviour’) questionnaire filled in by participating health workers. Qualitative data include semistructured interviews with TB health workers and patients, and with policy-makers at district and central levels in each country. Interviews will be analysed using the framework approach. The behavioural intervention delivery is audio recorded and assessed using a predefined fidelity coding index based on behavioural change technique taxonomy. Ethics and dissemination The study complies with the guidelines of the Declaration of Helsinki. Ethics approval for the study and process evaluation was granted by the University of Leeds (qualitative components), University of York (trial data and fidelity assessment), Bangladesh Medical Research Council and Bangladesh Drug Administration (trial data and qualitative

  19. News from the CERN Council

    CERN Multimedia

    The CERN Council today thanked the Organization’s outgoing management, and welcomed in the new. Outgoing Director General Robert Aymar, looked back on his five years at the helm, while new Director General, Rolf Heuer, presented his vision for the future. In other Council business, Romania was welcomed as a Candidate for Accession as Member State of CERN; and the groundwork was laid for a study of geographical and scientific extension of the role of CERN. Council also established the practical procedures for following projects relevant to the European Strategy for Particle Physics. Consult the complete Press Release.

  20. Large scale photovoltaic field trials. Second technical report: monitoring phase

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-09-15

    This report provides an update on the Large-Scale Building Integrated Photovoltaic Field Trials (LS-BIPV FT) programme commissioned by the Department of Trade and Industry (Department for Business, Enterprise and Industry; BERR). It provides detailed profiles of the 12 projects making up this programme, which is part of the UK programme on photovoltaics and has run in parallel with the Domestic Field Trial. These field trials aim to record the experience and use the lessons learnt to raise awareness of, and confidence in, the technology and increase UK capabilities. The projects involved: the visitor centre at the Gaia Energy Centre in Cornwall; a community church hall in London; council offices in West Oxfordshire; a sports science centre at Gloucester University; the visitor centre at Cotswold Water Park; the headquarters of the Insolvency Service; a Welsh Development Agency building; an athletics centre in Birmingham; a research facility at the University of East Anglia; a primary school in Belfast; and Barnstable civic centre in Devon. The report describes the aims of the field trials, monitoring issues, performance, observations and trends, lessons learnt and the results of occupancy surveys.

  1. Standardized End Point Definitions for Coronary Intervention Trials: The Academic Research Consortium-2 Consensus Document.

    Science.gov (United States)

    Garcia-Garcia, Hector M; McFadden, Eugène P; Farb, Andrew; Mehran, Roxana; Stone, Gregg W; Spertus, John; Onuma, Yoshinobu; Morel, Marie-Angèle; van Es, Gerrit-Anne; Zuckerman, Bram; Fearon, William F; Taggart, David; Kappetein, Arie-Pieter; Krucoff, Mitchell W; Vranckx, Pascal; Windecker, Stephan; Cutlip, Donald; Serruys, Patrick W

    2018-06-14

    The Academic Research Consortium (ARC)-2 initiative revisited the clinical and angiographic end point definitions in coronary device trials, proposed in 2007, to make them more suitable for use in clinical trials that include increasingly complex lesion and patient populations and incorporate novel devices such as bioresorbable vascular scaffolds. In addition, recommendations for the incorporation of patient-related outcomes in clinical trials are proposed. Academic Research Consortium-2 is a collaborative effort between academic research organizations in the United States and Europe, device manufacturers, and European, US, and Asian regulatory bodies. Several in-person meetings were held to discuss the changes that have occurred in the device landscape and in clinical trials and regulatory pathways in the last decade. The consensus-based end point definitions in this document are endorsed by the stakeholders of this document and strongly advocated for clinical trial purposes. This Academic Research Consortium-2 document provides further standardization of end point definitions for coronary device trials, incorporating advances in technology and knowledge. Their use will aid interpretation of trial outcomes and comparison among studies, thus facilitating the evaluation of the safety and effectiveness of these devices.

  2. 76 FR 62133 - National Women's Business Council

    Science.gov (United States)

    2011-10-06

    ... SMALL BUSINESS ADMINISTRATION National Women's Business Council AGENCY: U.S. Small Business... Business Council (NWBC). The meeting will be open to the public. DATES: The meeting will be held on Monday...., Appendix 2), SBA announces the meeting of the National Women's Business Council. The National Women's...

  3. Trump revives National Space Council

    Science.gov (United States)

    Johnston, Hamish

    2017-08-01

    US president Donald Trump has signed an executive order to re-establish the US National Space Council. The 12-member council will include key government officials with an interest in space exploration, including NASA’s acting administrator Robert Lightfoot and the secretaries of state, commerce and defence.

  4. Can emergency medicine research benefit from adaptive design clinical trials?

    Science.gov (United States)

    Flight, Laura; Julious, Steven A; Goodacre, Steve

    2017-04-01

    Adaptive design clinical trials use preplanned interim analyses to determine whether studies should be stopped or modified before recruitment is complete. Emergency medicine trials are well suited to these designs as many have a short time to primary outcome relative to the length of recruitment. We hypothesised that the majority of published emergency medicine trials have the potential to use a simple adaptive trial design. We reviewed clinical trials published in three emergency medicine journals between January 2003 and December 2013. We determined the proportion that used an adaptive design as well as the proportion that could have used a simple adaptive design based on the time to primary outcome and length of recruitment. Only 19 of 188 trials included in the review were considered to have used an adaptive trial design. A total of 154/165 trials that were fixed in design had the potential to use an adaptive design. Currently, there seems to be limited uptake in the use of adaptive trial designs in emergency medicine despite their potential benefits to save time and resources. Failing to take advantage of adaptive designs could be costly to patients and research. It is recommended that where practical and logistical considerations allow, adaptive designs should be used for all emergency medicine clinical trials. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  5. Supporting Policy In health with Research: an Intervention Trial (SPIRIT)—protocol for a stepped wedge trial

    Science.gov (United States)

    2014-01-01

    Introduction Governments in different countries have committed to better use of evidence from research in policy. Although many programmes are directed at assisting agencies to better use research, there have been few tests of the effectiveness of such programmes. This paper describes the protocol for SPIRIT (Supporting Policy In health with Research: an Intervention Trial), a trial designed to test the effectiveness of a multifaceted programme to build organisational capacity for the use of research evidence in policy and programme development. The primary aim is to determine whether SPIRIT results in an increase in the extent to which research and research expertise is sought, appraised, generated and used in the development of specific policy products produced by health policy agencies. Methods and analysis A stepped wedge cluster randomised trial involving six health policy agencies located in Sydney, Australia. Policy agencies are the unit of randomisation and intervention. Agencies were randomly allocated to one of three start dates (steps) to receive the 1-year intervention programme, underpinned by an action framework. The SPIRIT intervention is tailored to suit the interests and needs of each agency and includes audit, feedback and goal setting; a leadership programme; staff training; the opportunity to test systems to assist in the use of research in policies; and exchange with researchers. Outcome measures will be collected at each agency every 6 months for 30 months (starting at the beginning of step 1). Ethics and dissemination Ethics approval was granted by the University of Western Sydney Human Research and Ethics Committee HREC Approval H8855. The findings of this study will be disseminated broadly through peer-reviewed publications and presentations at conferences and used to inform future strategies. PMID:24989620

  6. A busy week for Council

    CERN Multimedia

    2009-01-01

    This has been a busy week for the CERN Council, and there is much to report. Firstly, I’m pleased to say that Council approved the Organization’s Medium Term Plan, and with it the budget for financial year 2010. In a time of global recession, this is a strong vote of confidence from the Member States. This meeting of Council provided an opportunity for the working group on the scientific and geographical enlargement of CERN to set out a roadmap towards its final report, which is to be made at Council’s December session this year. One part of the process over the coming months is to bring the major players in particle physics from beyond the European region into the discussion, ensuring that the working group’s recommendations lead to an optimum position for CERN and European particle physics in the global context. An indicator of the continuing attractiveness of CERN is the fact that Council has received four new applications...

  7. [Informed consent process in clinical trials: Insights of researchers, patients and general practitioners].

    Science.gov (United States)

    Giménez, Nuria; Pedrazas, David; Redondo, Susana; Quintana, Salvador

    2016-10-01

    Adequate information for patients and respect for their autonomy are mandatory in research. This article examined insights of researchers, patients and general practitioners (GPs) on the informed consent process in clinical trials, and the role of the GP. A cross-sectional study using three questionnaires, informed consent reviews, medical records, and hospital discharge reports. GPs, researchers and patients involved in clinical trials. Included, 504 GPs, 108 researchers, and 71 patients. Consulting the GP was recommended in 50% of the informed consents. Participation in clinical trials was shown in 33% of the medical records and 3% of the hospital discharge reports. GPs scored 3.54 points (on a 1-10 scale) on the assessment of the information received by the principal investigator. The readability of the informed consent sheet was rated 8.03 points by researchers, and the understanding was rated 7.68 points by patients. Patient satisfaction was positively associated with more time for reflection. GPs were not satisfied with the information received on the participation of patients under their in clinical trials. Researchers were satisfied with the information they offered to patients, and were aware of the need to improve the information GPs received. Patients collaborated greatly towards biomedical research, expressed satisfaction with the overall process, and minimised the difficulties associated with participation. Copyright © 2015 Elsevier España, S.L.U. All rights reserved.

  8. 76 FR 70779 - President's Council of Advisors on Science and Technology

    Science.gov (United States)

    2011-11-15

    ... University of Michigan North Campus Research Complex, 2800 Plymouth Road, Building 18, Ann Arbor, MI 48109... the University of Michigan North Research Complex from 8:30 a.m. to 2:45 p.m. on December 12, 2011... OFFICE OF SCIENCE AND TECHNOLOGY POLICY President's Council of Advisors on Science and Technology...

  9. Measures of outcome for stimulant trials: ACTTION recommendations and research agenda.

    Science.gov (United States)

    Kiluk, Brian D; Carroll, Kathleen M; Duhig, Amy; Falk, Daniel E; Kampman, Kyle; Lai, Shengan; Litten, Raye Z; McCann, David J; Montoya, Ivan D; Preston, Kenzie L; Skolnick, Phil; Weisner, Constance; Woody, George; Chandler, Redonna; Detke, Michael J; Dunn, Kelly; Dworkin, Robert H; Fertig, Joanne; Gewandter, Jennifer; Moeller, F Gerard; Ramey, Tatiana; Ryan, Megan; Silverman, Kenneth; Strain, Eric C

    2016-01-01

    The development and approval of an efficacious pharmacotherapy for stimulant use disorders has been limited by the lack of a meaningful indicator of treatment success, other than sustained abstinence. In March, 2015, a meeting sponsored by Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION) was convened to discuss the current state of the evidence regarding meaningful outcome measures in clinical trials for stimulant use disorders. Attendees included members of academia, funding and regulatory agencies, pharmaceutical companies, and healthcare organizations. The goal was to establish a research agenda for the development of a meaningful outcome measure that may be used as an endpoint in clinical trials for stimulant use disorders. Based on guidelines for the selection of clinical trial endpoints, the lessons learned from prior addiction clinical trials, and the process that led to identification of a meaningful indicator of treatment success for alcohol use disorders, several recommendations for future research were generated. These include a focus on the validation of patient reported outcome measures of functioning, the exploration of patterns of stimulant abstinence that may be associated with physical and/or psychosocial benefits, the role of urine testing for validating self-reported measures of stimulant abstinence, and the operational definitions for reduction-based measures in terms of frequency rather than quantity of stimulant use. These recommendations may be useful for secondary analyses of clinical trial data, and in the design of future clinical trials that may help establish a meaningful indicator of treatment success. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  10. Que faire? A Bioeconomy and Solar Energy Institute at Italy's Research Council in the Context of the Global Transition to the Solar Economy.

    Science.gov (United States)

    Pagliaro, Mario; Meneguzzo, Francesco

    2017-11-02

    Driven by insight for which new research and education requires new institutional organisation, and drawing on two decades of research and educational efforts, we devise the profile and activities of a new bioeconomy and solar energy institute at Italy's Research Council. We further articulate the institute's activities suggesting avenues on how to deploy sound and giving more useful research, education and policy advice in these crucial fields for making tomorrow's common development sustainable. The outcomes of the study are of general interest, because the transition to a solar economy is of intrinsic global nature and the challenges involved are similar in many countries. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. The Council of Psychological Advisers.

    Science.gov (United States)

    Sunstein, Cass R

    2016-01-01

    Findings in behavioral science, including psychology, have influenced policies and reforms in many nations. Choice architecture can affect outcomes even if material incentives are not involved. In some contexts, default rules, simplification, and social norms have had even larger effects than significant economic incentives. Psychological research is helping to inform initiatives in savings, finance, highway safety, consumer protection, energy, climate change, obesity, education, poverty, development, crime, corruption, health, and the environment. No nation has yet created a council of psychological advisers, but the role of behavioral research in policy domains is likely to grow in the coming years, especially in light of the mounting interest in promoting ease and simplification ("navigability"); in increasing effectiveness, economic growth, and competitiveness; and in providing low-cost, choice-preserving approaches.

  12. 76 FR 41824 - NASA Advisory Council; Science Committee; Meeting

    Science.gov (United States)

    2011-07-15

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice: (11-068)] NASA Advisory Council; Science... Aeronautics and Space Administration (NASA) announces a meeting of the Science Committee of the NASA Advisory..., 2011, 7:30 a.m. to 11:30 a.m., Local Time. ADDRESSES: NASA Ames Research Center, NASA Ames Conference...

  13. ITER council proceedings: 1998

    International Nuclear Information System (INIS)

    1999-01-01

    This volume contains documents of the 13th and the 14th ITER council meeting as well as of the 1st extraordinary ITER council meeting. Documents of the ITER meetings held in Vienna and Yokohama during 1998 are also included. The contents include an outline of the ITER objectives, the ITER parameters and design overview as well as operating scenarios and plasma performance. Furthermore, design features, safety and environmental characteristics are given

  14. CERN Council pauses for effect (LHC approval a step nearer)

    International Nuclear Information System (INIS)

    Anon.

    1994-01-01

    Aweek of intense diplomatic activity which had high level telephones ringing across Europe culminated in an imaginative and unexpected move on 24 June, when delegates adjourned the 100th session of CERN's governing body, Council, to be reconvened at a later date. On the Council table was the vote for CERN's next major machine, now universally agreed as the world focus of particle physics research for the start of the 21st century, the LHC proton-proton collider, to be built in CERN's 27-kilometre LEP tunnel, and the largest and most complex scientific joint effort ever undertaken in Europe

  15. Non-commercial vs. commercial clinical trials: a retrospective study of the applications submitted to a research ethics committee.

    Science.gov (United States)

    Fuentes Camps, Inmaculada; Rodríguez, Alexis; Agustí, Antonia

    2018-02-15

    There are many difficulties in undertaking independent clinical research without support from the pharmaceutical industry. In this retrospective observational study, some design characteristics, the clinical trial public register and the publication rate of noncommercial clinical trials were compared to those of commercial clinical trials. A total of 809 applications of drug-evaluation clinical trials were submitted from May 2004 to May 2009 to the research ethics committee of a tertiary hospital, and 16.3% of trials were noncommercial. They were mainly phase IV, multicentre national, and unmasked controlled trials, compared to the commercial trials that were mainly phase II or III, multicentre international, and double-blind masked trials. The commercial trials were registered and published more often than noncommercial trials. More funding for noncommercial research is still needed. The results of the research, commercial or noncommercial, should be disseminated in order not to compromise either its scientific or its social value. © 2018 The British Pharmacological Society.

  16. Council Districts

    Data.gov (United States)

    Town of Cary, North Carolina — View the location of the Town of Cary’s four Town Council districts.Please note that one district, District A, is split into two geo-spatial areas. One area is in...

  17. 78 FR 64200 - Caribbean Fishery Management Council; Public Meetings

    Science.gov (United States)

    2013-10-28

    ... Caribbean Fishery Management Council's (Council) Scientific and Statistical Committee (SSC) will hold... Fishery Management Council; Public Meetings AGENCY: National Marine Fisheries Service (NMFS), National... held at the Caribbean Fishery Management Council Headquarters, located at 270 Mu[ntilde]oz Rivera...

  18. 75 FR 49890 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-08-16

    ... Pacific Fishery Management Council's (Pacific Council) Coastal Pelagic Species Management Team (CPSMT) and... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... will be available at the following location: Pacific Fishery Management Council, Small Conference Room...

  19. How many research nurses for how many clinical trials in an oncology setting? Definition of the Nursing Time Required by Clinical Trial-Assessment Tool (NTRCT-AT).

    Science.gov (United States)

    Milani, Alessandra; Mazzocco, Ketti; Stucchi, Sara; Magon, Giorgio; Pravettoni, Gabriella; Passoni, Claudia; Ciccarelli, Chiara; Tonali, Alessandra; Profeta, Teresa; Saiani, Luisa

    2017-02-01

    Few resources are available to quantify clinical trial-associated workload, needed to guide staffing and budgetary planning. The aim of the study is to describe a tool to measure clinical trials nurses' workload expressed in time spent to complete core activities. Clinical trials nurses drew up a list of nursing core activities, integrating results from literature searches with personal experience. The final 30 core activities were timed for each research nurse by an outside observer during daily practice in May and June 2014. Average times spent by nurses for each activity were calculated. The "Nursing Time Required by Clinical Trial-Assessment Tool" was created as an electronic sheet that combines the average times per specified activities and mathematic functions to return the total estimated time required by a research nurse for each specific trial. The tool was tested retrospectively on 141 clinical trials. The increasing complexity of clinical research requires structured approaches to determine workforce requirements. This study provides a tool to describe the activities of a clinical trials nurse and to estimate the associated time required to deliver individual trials. The application of the proposed tool in clinical research practice could provide a consistent structure for clinical trials nursing workload estimation internationally. © 2016 John Wiley & Sons Australia, Ltd.

  20. 78 FR 26616 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-05-07

    ... Pacific Fishery Management Council's (Pacific Council) Groundfish Management Team (GMT) will hold a... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... number) and use the access code 802-457-985 when prompted. Council address: Pacific Fishery Management...

  1. 75 FR 33245 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-06-11

    ... Pacific Fishery Management Council's (Council) Groundfish Management Team (GMT) will hold a working... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... be held at the Pacific Fishery Management Council office, Large Conference Room, 7700 NE Ambassador...

  2. 77 FR 21972 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-04-12

    ... Pacific Fishery Management Council's (Council) Highly Migratory Species Management Team (HMSMT) will hold... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... work sessions will be held at Large Conference Room, Pacific Fishery Management Council Office, 7700 NE...

  3. 77 FR 57558 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-09-18

    ... Pacific Fishery Management Council's (Pacific Council) Groundfish Management Team (GMT) will hold a... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... Management Council, 7700 NE Ambassador Place, Suite 101, Portland, OR 97220-1384. FOR FURTHER INFORMATION...

  4. 78 FR 33856 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2013-06-05

    ...-FVWF97920900000-XXX] Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife Service, Interior... public teleconference of the Sport Fishing and Boating Partnership Council (Council). DATES... announce that Sport Fishing and Boating Partnership Council will hold a teleconference. Background The...

  5. 76 FR 68719 - Mid-Atlantic Fishery Management Council; Public Meeting

    Science.gov (United States)

    2011-11-07

    ... Mid-Atlantic Fishery Management Council's (Council) Scientific and Statistical Committee (SSC) will... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National....org . Council address: Mid-Atlantic Fishery Management Council, 800 North State Street, Suite 201...

  6. ITER Council proceedings: 1993

    International Nuclear Information System (INIS)

    1994-01-01

    Records of the third ITER Council Meeting (IC-3), held on 21-22 April 1993, in Tokyo, Japan, and the fourth ITER Council Meeting (IC-4) held on 29 September - 1 October 1993 in San Diego, USA, are presented, giving essential information on the evolution of the ITER Engineering Design Activities (EDA), such as the text of the draft of Protocol 2 further elaborated in ''ITER EDA Agreement and Protocol 2'' (ITER EDA Documentation Series No. 5), recommendations on future work programmes: a description of technology R and D tasks; the establishment of a trust fund for the ITER EDA activities; arrangements for Visiting Home Team Personnel; the general framework for the involvement of other countries in the ITER EDA; conditions for the involvement of Canada in the Euratom Contribution to the ITER EDA; and other attachments as parts of the Records of Decision of the aforementioned ITER Council Meetings

  7. ITER council proceedings: 1993

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    Records of the third ITER Council Meeting (IC-3), held on 21-22 April 1993, in Tokyo, Japan, and the fourth ITER Council Meeting (IC-4) held on 29 September - 1 October 1993 in San Diego, USA, are presented, giving essential information on the evolution of the ITER Engineering Design Activities (EDA), such as the text of the draft of Protocol 2 further elaborated in ``ITER EDA Agreement and Protocol 2`` (ITER EDA Documentation Series No. 5), recommendations on future work programmes: a description of technology R and D tastes; the establishment of a trust fund for the ITER EDA activities; arrangements for Visiting Home Team Personnel; the general framework for the involvement of other countries in the ITER EDA; conditions for the involvement of Canada in the Euratom Contribution to the ITER EDA; and other attachments as parts of the Records of Decision of the aforementioned ITER Council Meetings.

  8. 77 FR 51968 - Mid-Atlantic Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-08-28

    ... Mid-Atlantic Fishery Management Council's (Council) Scientific and Statistical Committee (SSC) will... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National....mafmc.org . Council address: Mid-Atlantic Fishery Management Council, 800 North State Street, Suite 201...

  9. "Science and Peace" symposium to celebrate the 60th anniversary of the first Council session | 19 September

    CERN Multimedia

    2014-01-01

    Friday 19 September 2014 In the tent behind the Globe of Science and Innovation The Convention for the Establishment of a European Organization for Nuclear Research entered into force on 29 September 1954, 60 years ago. This marks CERN's official birthday. The first session of the CERN Council, the governance of CERN, was held in Geneva on 7 and 8 October 1954, just one week later. The symposium "Science and Peace" is being held to celebrate the 60th anniversary of the first Council session. Speakers from all generations will present highlights from 60 years of the Council and various views from their own perspectives. Programme 3.00 - 3.10 p.m.: Welcome address - Agnieszka Zalewska 3.10 - 3.25 p.m.: The history of the Council: a brief selection of highlights - Jens Vigen 3.25 - 3.40 p.m.: The Council as seen by a Member State - Sijbrand De Jong 3.40 - 3.55 p.m.: The Council as seen by an outreach specialist - Steven Goldfarb 3.55 - 4.10 p.m.: The Council as seen by a young scie...

  10. Trial Promoter: A Web-Based Tool for Boosting the Promotion of Clinical Research Through Social Media.

    Science.gov (United States)

    Reuter, Katja; Ukpolo, Francis; Ward, Edward; Wilson, Melissa L; Angyan, Praveen

    2016-06-29

    Scarce information about clinical research, in particular clinical trials, is among the top reasons why potential participants do not take part in clinical studies. Without volunteers, on the other hand, clinical research and the development of novel approaches to preventing, diagnosing, and treating disease are impossible. Promising digital options such as social media have the potential to work alongside traditional methods to boost the promotion of clinical research. However, investigators and research institutions are challenged to leverage these innovations while saving time and resources. To develop and test the efficiency of a Web-based tool that automates the generation and distribution of user-friendly social media messages about clinical trials. Trial Promoter is developed in Ruby on Rails, HTML, cascading style sheet (CSS), and JavaScript. In order to test the tool and the correctness of the generated messages, clinical trials (n=46) were randomized into social media messages and distributed via the microblogging social media platform Twitter and the social network Facebook. The percent correct was calculated to determine the probability with which Trial Promoter generates accurate messages. During a 10-week testing phase, Trial Promoter automatically generated and published 525 user-friendly social media messages on Twitter and Facebook. On average, Trial Promoter correctly used the message templates and substituted the message parameters (text, URLs, and disease hashtags) 97.7% of the time (1563/1600). Trial Promoter may serve as a promising tool to render clinical trial promotion more efficient while requiring limited resources. It supports the distribution of any research or other types of content. The Trial Promoter code and installation instructions are freely available online.

  11. Council for Nuclear Safety annual report 1988/89

    International Nuclear Information System (INIS)

    1989-01-01

    An overview of the structure, duties and activities of the Council for Nuclear Safety during 1988/1989 is presented in this annual report. It is the Council's first duty to ensure that all aspects - siting, design, construction and operation - in all areas of the nuclear industry, from mining of the nuclear ores to the ultimate disposal of nuclear waste, are conducted in such a manner that the potential for harm associated with the radioactive properties of the materials involved is kept under proper control. In order to achieve this the Council is responsible for the establishment and application of safety standards, the issuing of nuclear licenses and the evaluation and inspection of nuclear installations to ensure that the licensees are complying with the conditions laid down in the license and that they are adhering to all the safety criteria established by the Council. Other information contained in this annual report is, inter alia, the financial statements of the Council, the meetings attended by members of the Council and the administrative and management aspects of the Council. 8 figs

  12. A model for promoting democracy by using the corporate culture of secondary school student councils in North-eastern Thailand

    Directory of Open Access Journals (Sweden)

    Nongkran Anukul

    2015-11-01

    Full Text Available This research aims to investigate the history of secondary school student councils in North-eastern Thailand (Isan, to study the present conditions and problems of secondary school student councils in Isan and to study a model for promoting democracy by using the corporate culture of secondary school student councils in Isan. The study area encompassed Kalasin Province, including Somdetpittayakom School in Somdet District and Yangtaladwittayakarn School in Yangtalat District, Mahasarakham Province, including Sarakhampittayakhom School in Muang District and Kantarawichai School in Kantarawichai District, and Khon Kaen Province, including Kallayanawat School in Muang District and Nampong Suksa School in Nampong District. This research employed interview, observation and focus groups as data collection tools with a purposive sample of student councils in secondary schools in Isan. Data was verified and validated using a triangulation method and analyzed by descriptive analysis. Research results show that the student councils in the secondary schools of Isan were established to promote democracy among youth. Students gained knowledge, understanding of the democratic system, experience in student administration and governance by students for students. It was also found that student council activities in secondary schools give students opportunities to know about their roles, acceptance, respect rights and duties, use intellect to solve problems, have faith in the democratic system, develop morality and ethics and preserve and disseminate traditions and culture according to the principles of Dharma. Current problems with student councils include no student interest in duties and no relationship between the elected leaders and their constituency. Selfishness, dishonesty and ignorance are the causes of non-transparent school councils with no responsibility, no response to student needs, lack of rights, justice and effectiveness, lacking of creative

  13. Challenges, Changes, and Impact of the Council on Social Work Education Women's Council: An Update

    Science.gov (United States)

    Tower, Leslie E.; Lazzari, Marceline M.; Faul, Anna C.; Alvarez, Ann Rosegrant

    2015-01-01

    This article highlights the contributions of the Council on the Role and Status of Women in Social Work Education (Women's Council) as well as the role and status of women in social work education. For this historical analysis update, the authors drew on several primary and secondary data sources. The first major theme was organizational…

  14. 76 FR 47606 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2011-08-05

    ...] Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife Service, Interior. ACTION... Sport Fishing and Boating Partnership Council (Council). DATES: The meeting will be held on Wednesday... Advisory Committee Act, 5 U.S.C. App., we announce that the Sport Fishing and Boating Partnership Council...

  15. Current Activities of the Joint Council on Economic Education.

    Science.gov (United States)

    Highsmith, Robert J.

    1987-01-01

    Reviews current activities of the Joint Council, among them, a researcher training institute, a new K-12 economic education scope and sequence document, a junior high level test of economic knowledge, an instructional package for advanced placement classes, a textbook conference, a project to help teachers of students who work with at-risk…

  16. 78 FR 61866 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2013-10-04

    ...-FVWF97920900000-XXX] Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife Service, Interior... meeting of the Sport Fishing and Boating Partnership Council (Council). A Federal advisory committee, the... Advisory Committee Act, 5 U.S.C. App., we announce that the Sport Fishing and Boating Partnership Council...

  17. How Sustainable is Democratic Innovation? Tracking Neighborhood Councils in Montevideo

    Directory of Open Access Journals (Sweden)

    Uwe Serdült

    2015-01-01

    Full Text Available Focusing on the relatively longstanding experience of neighborhood councils in the Uruguayan capital of Montevideo (1993–, this research note seeks to analyze how sustainable democratic innovation is and to explain subsequent results. Sustainability is assessed through the evolution of citizens’ participation in elections and through the number of candidates who apply to become neighborhood councilors. For both indicators, a consistent decline in the levels of participation over time is found. This is deemed to be a consequence of an institutional design that seriously limits the performance of neighborhood councils in terms of their influence in the decision-making process and their acquisition of legitimacy and political capital.

  18. 75 FR 32375 - New England Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-06-08

    ... associated with the Joint Groundfish/Sea Scallop Committee. The afternoon session will begin with an overview...-year research priorities and an ecosystem-based fisheries management white paper. This report will be... Council meeting will include a review of any experimental fishery permit applications that have been...

  19. Influences on visit retention in clinical trials: insights from qualitative research during the VOICE trial in Johannesburg, South Africa.

    Science.gov (United States)

    Magazi, Busisiwe; Stadler, Jonathan; Delany-Moretlwe, Sinead; Montgomery, Elizabeth; Mathebula, Florence; Hartmann, Miriam; van der Straten, Ariane

    2014-07-28

    Although significant progress has been made in clinical trials of women-controlled methods of HIV prevention such as microbicides and Pre-exposure Prophylaxis (PrEP), low adherence to experimental study products remains a major obstacle to being able to establish their efficacy in preventing HIV infection. One factor that influences adherence is the ability of trial participants to attend regular clinic visits at which trial products are dispensed, adherence counseling is administered, and participant safety is monitored. We conducted a qualitative study of the social contextual factors that influenced adherence in the VOICE (MTN-003) trial in Johannesburg, South Africa, focusing on study participation in general, and study visits in particular. The research used qualitative methodologies, including in-depth interviews (IDI), serial ethnographic interviews (EI), and focus group discussions (FGD) among a random sub-sample of 102 female trial participants, 18 to 40 years of age. A socio-ecological framework that explored those factors that shaped trial participation and adherence to study products, guided the analysis. Key codes were developed to standardize subsequent coding and a node search was used to identify texts relating to obstacles to visit adherence. Our analysis includes coded transcripts from seven FGD (N = 40), 41 IDI, and 64 serial EI (N = 21 women). Women's kinship, social, and economic roles shaped their ability to participate in the clinical trial. Although participants expressed strong commitments to attend study visits, clinic visit schedules and lengthy waiting times interfered with their multiple obligations as care givers, wage earners, housekeepers, and students. The research findings highlight the importance of the social context in shaping participation in HIV prevention trials, beyond focusing solely on individual characteristics. This points to the need to focus interventions to improve visit attendance by promoting a culture of

  20. Evaluation of cluster-randomized trials on maternal and child health research in developing countries

    DEFF Research Database (Denmark)

    Handlos, Line Neerup; Chakraborty, Hrishikesh; Sen, Pranab Kumar

    2009-01-01

    To summarize and evaluate all publications including cluster-randomized trials used for maternal and child health research in developing countries during the last 10 years. METHODS: All cluster-randomized trials published between 1998 and 2008 were reviewed, and those that met our criteria...... for inclusion were evaluated further. The criteria for inclusion were that the trial should have been conducted in maternal and child health care in a developing country and that the conclusions should have been made on an individual level. Methods of accounting for clustering in design and analysis were......, and the trials generally improved in quality. CONCLUSIONS: Shortcomings exist in the sample-size calculations and in the analysis of cluster-randomized trials conducted during maternal and child health research in developing countries. Even though there has been improvement over time, further progress in the way...

  1. 78 FR 65717 - Federal Salary Council

    Science.gov (United States)

    2013-11-01

    ... OFFICE OF PERSONNEL MANAGEMENT Federal Salary Council AGENCY: Office of Personnel Management. ACTION: Notice of meeting. SUMMARY: The Federal Salary Council meeting originally scheduled for November... establishment or modification of locality pay areas, the coverage of salary surveys, the process of comparing...

  2. Ethical and policy issues in cluster randomized trials: rationale and design of a mixed methods research study

    Directory of Open Access Journals (Sweden)

    Chaudhry Shazia H

    2009-07-01

    Full Text Available Abstract Background Cluster randomized trials are an increasingly important methodological tool in health research. In cluster randomized trials, intact social units or groups of individuals, such as medical practices, schools, or entire communities – rather than individual themselves – are randomly allocated to intervention or control conditions, while outcomes are then observed on individual cluster members. The substantial methodological differences between cluster randomized trials and conventional randomized trials pose serious challenges to the current conceptual framework for research ethics. The ethical implications of randomizing groups rather than individuals are not addressed in current research ethics guidelines, nor have they even been thoroughly explored. The main objectives of this research are to: (1 identify ethical issues arising in cluster trials and learn how they are currently being addressed; (2 understand how ethics reviews of cluster trials are carried out in different countries (Canada, the USA and the UK; (3 elicit the views and experiences of trial participants and cluster representatives; (4 develop well-grounded guidelines for the ethical conduct and review of cluster trials by conducting an extensive ethical analysis and organizing a consensus process; (5 disseminate the guidelines to researchers, research ethics boards (REBs, journal editors, and research funders. Methods We will use a mixed-methods (qualitative and quantitative approach incorporating both empirical and conceptual work. Empirical work will include a systematic review of a random sample of published trials, a survey and in-depth interviews with trialists, a survey of REBs, and in-depth interviews and focus group discussions with trial participants and gatekeepers. The empirical work will inform the concurrent ethical analysis which will lead to a guidance document laying out principles, policy options, and rationale for proposed guidelines. An

  3. 78 FR 15110 - National Women's Business Council; Meeting

    Science.gov (United States)

    2013-03-08

    ... SMALL BUSINESS ADMINISTRATION National Women's Business Council; Meeting AGENCY: U.S. Small... Women's Business Council (NWBC). The meeting will be open to the public. DATES: The meeting will be held... (5 U.S.C., Appendix 2), SBA announces the meeting of the National Women's Business Council. The...

  4. 45 CFR 1603.8 - Corporation support of council.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Corporation support of council. 1603.8 Section 1603.8 Public Welfare Regulations Relating to Public Welfare (Continued) LEGAL SERVICES CORPORATION STATE ADVISORY COUNCILS § 1603.8 Corporation support of council. (a) The Corporation shall inform the...

  5. 26th May 2011 -Delegate to CERN Open Council sessions and European Commission Head of Unit for Joint Programming European Research Area, DG Research and Innovation R. Lečbychová visiting the CERN Control Centre with M. Pojer, accompanied by CERN S. Stavrev.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    26th May 2011 -Delegate to CERN Open Council sessions and European Commission Head of Unit for Joint Programming European Research Area, DG Research and Innovation R. Lečbychová visiting the CERN Control Centre with M. Pojer, accompanied by CERN S. Stavrev.

  6. Reconciling research and community priorities in participatory trials: application to Padres Informados/Jovenes Preparados.

    Science.gov (United States)

    Allen, Michele L; Garcia-Huidobro, Diego; Bastian, Tiana; Hurtado, G Ali; Linares, Roxana; Svetaz, María Veronica

    2017-06-01

    Participatory research (PR) trials aim to achieve the dual, and at times competing, demands of producing an intervention and research process that address community perspectives and priorities, while establishing intervention effectiveness. To identify research and community priorities that must be reconciled in the areas of collaborative processes, study design and aim and study implementation quality in order to successfully conduct a participatory trial. We describe how this reconciliation was approached in the smoking prevention participatory trial Padres Informados/Jovenes Preparados (Informed Parents/Prepared Youth) and evaluate the success of our reconciled priorities. Data sources to evaluate success of the reconciliations included a survey of all partners regarding collaborative group processes, intervention participant recruitment and attendance and surveys of enrolled study participants assessing intervention outcomes. While we successfully achieved our reconciled collaborative processes and implementation quality goals, we did not achieve our reconciled goals in study aim and design. Due in part to the randomized wait-list control group design chosen in the reconciliation process, we were not able to demonstrate overall efficacy of the intervention or offer timely services to families in need of support. Achieving the goals of participatory trials is challenging but may yield community and research benefits. Innovative research designs are needed to better support the complex goals of participatory trials. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  7. Impact of radiation research on clinical trials in radiation oncology

    International Nuclear Information System (INIS)

    Rubin, P.; Van Ess, J.D.

    1989-01-01

    The authors present an outline review of the history of the formation of the cooperative group called International Clinical Trials in Radiation Oncology (ICTRO), and the following areas are briefly discussed together with some projections for the direction of clinical trials in radiation oncology into the 1990s:- radiosensitizers, radioprotectors, and their combination, drug-radiation interactions, dose/time/fractionation, hyperthermia, biological response modifiers and radiolabelled antibodies, high LET, particularly neutron therapy, large field irradiation and interoperative irradiation, research studies on specific sites. (U.K.)

  8. 75 FR 68010 - Federal Salary Council

    Science.gov (United States)

    2010-11-04

    ... OFFICE OF PERSONNEL MANAGEMENT Federal Salary Council AGENCY: Office of Personnel Management. ACTION: Notice of meeting. SUMMARY: The Federal Salary Council will meet on November 19, 2010, at the... establishment or modification of locality pay areas, the coverage of salary surveys, the process of comparing...

  9. 77 FR 29321 - National Coal Council

    Science.gov (United States)

    2012-05-17

    ... DEPARTMENT OF ENERGY National Coal Council AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the National Coal Council (NCC). The Federal Advisory...., Washington, DC 20585-1290; Telephone: 202-586-0429. SUPPLEMENTARY INFORMATION: Purpose of Meeting: The Coal...

  10. 76 FR 9765 - National Coal Council

    Science.gov (United States)

    2011-02-22

    ... DEPARTMENT OF ENERGY National Coal Council AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the National Coal Council (NCC). The Federal Advisory... Chairman Joe Hopf. Presentation by Coal Policy Committee Chairman Frank Blake on the findings and...

  11. 75 FR 48320 - National Petroleum Council

    Science.gov (United States)

    2010-08-10

    ... DEPARTMENT OF ENERGY National Petroleum Council AGENCY: Department of Energy, Office of Fossil Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the National Petroleum Council. The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770) requires that public...

  12. Potential of adaptive clinical trial designs in pharmacogenetic research, A simulation based on the IPASS trial

    NARCIS (Netherlands)

    Van Der Baan, Frederieke H.; Knol, Mirjam J.|info:eu-repo/dai/nl/304820350; Klungel, Olaf H.|info:eu-repo/dai/nl/181447649; Egberts, Toine C.G.|info:eu-repo/dai/nl/162850050; Grobbee, Diederick E.; Roes, Kit C.B.

    2011-01-01

    Background: An adaptive clinical trial design that allows population enrichment after interim analysis can be advantageous in pharmacogenetic research if previous evidence is not strong enough to exclude part of the patient population beforehand.With this design, underpowered studies or unnecessary

  13. 76 FR 45232 - Mid-Atlantic Fishery Management Council (MAFMC); Meetings

    Science.gov (United States)

    2011-07-28

    ... Council will finalize scup, black sea bass, summer flounder, and bluefish management measures for 2012 in... Bass, and Bluefish Boards. From 4 until 5 p.m., Research Set Aside priorities will be discussed for... Flounder, Scup, Black Sea Bass and Bluefish Boards will review the Scientific and Statistical Committee's...

  14. 75 FR 66357 - New England Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-10-28

    ... Commission, as well as NOAA Enforcement and the Chairman of the Research Steering Committee. There will be a review of any experimental fishery permit applications that have been received since the last Council... will include an overview of the committee=s 2011 schedule, approval of an acceptable biological catch...

  15. Council Session

    CERN Multimedia

    CERN PhotoLab

    1977-01-01

    From face, 1st raw: Erich Lohrmann, Sergio Fubini, Léon Van Hove, John Adams (Directors-General), Paul Levaux (President of the Council) Hans-Otto Wüster, Franco Bonaudi, Robert Lévy-Mandel and 2nd raw, centre: Patrick Mollet, Eliane de Modzelewska, Jean-Marie Dufour

  16. 77 FR 59026 - Federal Salary Council

    Science.gov (United States)

    2012-09-25

    ... OFFICE OF PERSONNEL MANAGEMENT Federal Salary Council AGENCY: Office of Personnel Management. ACTION: Notice of meeting. SUMMARY: The Federal Salary Council will meet on October 19, 2012, at the time... establishment or modification of locality pay areas, the coverage of salary surveys, the process of comparing...

  17. Health council report 'Antimicrobial growth promoters'.

    NARCIS (Netherlands)

    Goettsch, W; Degener, JE

    1999-01-01

    The Health Council of the Netherlands has issued a report on the risk of development of resistance among bacteria as result of the use of antibiotics as growth promotors in livestock farming. The committee appointed by the Health Council conclude that the use of antimicrobial growth promotors

  18. 77 FR 2714 - National Petroleum Council

    Science.gov (United States)

    2012-01-19

    ... DEPARTMENT OF ENERGY National Petroleum Council AGENCY: Office of Fossil Energy, Department of Energy. ACTION: Notice of Renewal. SUMMARY: Pursuant to Section 14(a)(2)(A) of the Federal Advisory... Services Administration, notice is hereby given that the National Petroleum Council has been renewed for a...

  19. Asthma: NIH-Sponsored Research and Clinical Trials | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... of this page please turn Javascript on. Feature: Asthma Asthma: NIH-Sponsored Research and Clinical Trials Past Issues / Fall 2011 Table of Contents NIH-Sponsored Research Asthma in the Inner City: Recognizing that asthma severity ...

  20. Research staff training in a multisite randomized clinical trial: Methods and recommendations from the Stimulant Reduction Intervention using Dosed Exercise (STRIDE) trial.

    Science.gov (United States)

    Walker, Robrina; Morris, David W; Greer, Tracy L; Trivedi, Madhukar H

    2014-01-01

    Descriptions of and recommendations for meeting the challenges of training research staff for multisite studies are limited despite the recognized importance of training on trial outcomes. The STRIDE (STimulant Reduction Intervention using Dosed Exercise) study is a multisite randomized clinical trial that was conducted at nine addiction treatment programs across the United States within the National Drug Abuse Treatment Clinical Trials Network (CTN) and evaluated the addition of exercise to addiction treatment as usual (TAU), compared to health education added to TAU, for individuals with stimulant abuse or dependence. Research staff administered a variety of measures that required a range of interviewing, technical, and clinical skills. In order to address the absence of information on how research staff are trained for multisite clinical studies, the current manuscript describes the conceptual process of training and certifying research assistants for STRIDE. Training was conducted using a three-stage process to allow staff sufficient time for distributive learning, practice, and calibration leading up to implementation of this complex study. Training was successfully implemented with staff across nine sites. Staff demonstrated evidence of study and procedural knowledge via quizzes and skill demonstration on six measures requiring certification. Overall, while the majority of staff had little to no experience in the six measures, all research assistants demonstrated ability to correctly and reliably administer the measures throughout the study. Practical recommendations are provided for training research staff and are particularly applicable to the challenges encountered with large, multisite trials.

  1. 75 FR 2488 - Mid-Atlantic Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-01-15

    ... Mid-Atlantic Fishery Management Council's (MAFMC) Scientific and Statistical Committee (SSC) will hold... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... 21240; telephone: (410) 859-3300. Council address: Mid-Atlantic Fishery Management Council, 300 S. New...

  2. 78 FR 4399 - National Advisory Council on Indian Education (NACIE)

    Science.gov (United States)

    2013-01-22

    ... DEPARTMENT OF EDUCATION National Advisory Council on Indian Education (NACIE) AGENCY: U.S... the upcoming public meeting of the National Advisory Council on Indian Education (the Council) and is... Final Agenda). SUPPLEMENTARY INFORMATION: The National Advisory Council on Indian Education is...

  3. Elections to Staff Council

    CERN Multimedia

    Staff Association

    2013-01-01

    Elections to fill all seats in the Staff Council are being organized this month. The voting takes place from the 28 of October to the 11th of November, at noon. As you may have noted when reading Echo, many issues concerning our employment conditions are on the agenda of the coming months, and in particular the Five-yearly-Review 2015, subject of the questionnaire that you probably recently filled out. All this will keep the next Staff Council very busy indeed. So, make your voice heard and take part in the elections for a new Staff Council. By doing so, you will be encouraging the men and women who will be representing you over the next two years and they will doubtless appreciate your gratitude. Every member of the Staff Association will have received an email containing a link to the webpage which will allow voting. If you are a member of the Staff Association and you did not receive such an email, please contact the Staff Association secretariat (staff.association@cern.ch). Do not forget to v...

  4. Challenges Affecting Participation In Provision Of Public Services In Arusha City Council Tanzania

    Directory of Open Access Journals (Sweden)

    Joel

    2015-08-01

    Full Text Available ABSTRACT In recently world creating opportunities under appropriate circumstances for people to manipulate decisions that affect them will increase the sense of ownership and care that is why participation has become a question of concern for any public and private project development and sustainability. The purpose of this study was to assessing the challenges affecting participation in provision of public services in Arusha city council. The specific objective of this study was to find out the challenges affecting public consultations and involvement in provision of public services at Arusha city council. The researcher use survey design technique in studying 150 samples from 416442 which included public citizens mayor councilors and employees at the Arusha city council office. The sample was selected through non- probability sampling techniques which was purposive and convenience. The data was collected through questionnaire and structured interview schedule and data was qualitatively analyzed where the factual and logical interpretation was explained through using of table and percentages. From the findings of the study provision of effective public services in Arusha city council is less effective and unsatisfactory because of insufficient number of staff poor technology conservatism bureaucracy culture relationship politics and poor communication. In order to address the issues the researcher recommends that the governance is weak and it needed to be reviewed in order to enhance the effectiveness of the entire process in provision of effective public services.

  5. 75 FR 7234 - South Atlantic Fishery Management Council; Public Meetings

    Science.gov (United States)

    2010-02-18

    ... meeting to provide an overview of the NOAA draft catch share policy, updates on all catch share draft... National Center for Coastal Ocean Research's Eat Lionfish Campaign, review draft policy on invasive species... appropriate. From 1:45 p.m. - 2 p.m., the Council will review and develop recommendations on Experimental...

  6. 77 FR 2038 - New England Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-01-13

    ... receive an update on progress to date on Essential Fish Habitat (EFH) Omnibus 2, which is focusing on the development of management alternatives to minimize the adverse effects of fishing activities on essential fish habitat and the protection of deep sea corals. Next, the Council's Research Steering Committee will review...

  7. 76 FR 72906 - Mid-Atlantic Fishery Management Council (MAFMC); Public Meetings

    Science.gov (United States)

    2011-11-28

    ... Council will receive a presentation on Fishery Management Councils: Decision-making, Communication, and... Council will conduct its regular Business Session, receive Organizational Reports, Council Liaison Reports... Biedron of Cornell University on Fishery Management Councils: Decision-making, Communication, and Social...

  8. Strategies on Technology Transfer and Patents Commercialization for Nanotechnology at the Spanish National Research Council.

    Science.gov (United States)

    Maira, Javier; Etxabe, Javier; Serena, Pedro A

    2018-02-14

    Nanoscience and nanotechnology made their appearance in the scientific scene at a time when both the economy of Spain and the Spanish Research and Innovation System were experiencing strong growth. This circumstance resulted in a remarkable development of nanoscience and nanotechnology especially in universities and public research institutions such as the Spanish National Research Council (Consejo Superior de Investigaciones Científicas-CSIC). However, this development in academia has not been reflected in a similar increment in the transfer of knowledge to the productive sector despite several efforts and initiatives were launched. The CSIC, the main generator of scientific knowledge in Spain, has designed and implemented a series of actions in order to take advantage of the knowledge generated in nanotechnology by its research groups by mean of an appropriate transfer to both the Spanish and the international industry. Internal methodologies used in CSIC in order to protect and commercialize nanotechnology based intellectual property as well as their effects are reviewed. The evolution of CSIC nanotechnology patents portfolio is also analyzed. There has been a clear increase in the patent license agreements of CSIC in the period 2002- 2015 in the field of nanotechnology. This increase is correlated to these facts: (i) Highly qualified team managing Intellectual Property issues, (ii) The presence of CSIC in international fairs, and (iii) Proactive search of companies and investors. Successful results can be achieved in technology transfer when the appropriate resources are available and properly organized with an adequate combination of efforts in knowledge protection, promotion and commercialization of technologies and support to the scientific entrepreneurs of the institution. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  9. An Issues-Based Research Project: National Goals on Trial.

    Science.gov (United States)

    DeVille, Priscilla; And Others

    This paper summarizes the results of a research project completed by three doctoral students enrolled in an advanced curriculum development course at the University of Southern Mississippi (Hattiesburg). The students used a mock trial format to consider reasons to support establishment of a national curriculum (concerning the American public's…

  10. Open letter to President of CERN Council

    CERN Multimedia

    Association du personnel

    2010-01-01

    Geneva, 1 February 2010 Dear President of Council, The active and retired members of the Pension Fund are very concerned and indignant about the way in which Council is dealing with the alarming question of the balance of the Fund. Indeed, in 2004 the actuarial review had alerted Council to the matter of the technical deficit of the scheme and the insufficient funding of its benefit scheme. At that time, Council contented itself with putting in place a mechanism of under-indexation of pensions – arbitrary and discriminatory in that it called on the solidarity of the pensioners only – and with deciding on a very small increase in contributions to the Fund, a token measure having no relation to the size of the problem. Since 2004, all that Council has done is to ask for one study after another: in December 2004, December 2005, December 2006, June 2007, and June 2008. The conclusions of the last study, carried out by the Pension Fund Governing Board, were presented on 11 November 2009. Th...

  11. 77 FR 53179 - North Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-08-31

    .... SUMMARY: The North Pacific Fishery Management Council's (NPFMC) Crab Plan Team (CPT) will meet in Seattle... Pacific Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS..., WA. Council address: North Pacific Fishery Management Council, 605 W. 4th Avenue, Suite 306...

  12. 78 FR 53156 - Sport Fishing and Boating Partnership Council; Teleconference

    Science.gov (United States)

    2013-08-28

    ...-FVWF97920900000-XXX] Sport Fishing and Boating Partnership Council; Teleconference AGENCY: Fish and Wildlife... (Service), announce a public teleconference of the Sport Fishing and Boating Partnership Council (Council.... App., we announce that Sport Fishing and Boating Partnership Council will hold a teleconference...

  13. 78 FR 20616 - Western Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-04-05

    ... Pacific Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS.... SUMMARY: The Western Pacific Fishery Management Council (Council) will hold meeting of its Pelagics Plan... the Council Pelagics Conference Room to discuss the following agenda items: Tuesday, April 23, 2013, 8...

  14. ITER Council tour of Clarington site

    International Nuclear Information System (INIS)

    Dautovich, D.

    2001-01-01

    The ITER Council meeting was recently held in Toronto on 27 and 28 February. ITER Canada provided local arrangements for the Council meeting on behalf of Europe as the Official host. Following the meeting, on 1 March, ITER Canada conducted a tour of the proposed ITER construction site at Charington, and the ITER Council members attended a luncheon followed by a speech by Dr. Peter Barnard, Chairman and CEO of ITER Canada, at the Empire Club of Canada. The official invitation to participate in these events came from Dr. Peter Harrison, Deputy Minister of Natural Resources Canada. This report provides a brief summary of the events on 1 March

  15. 77 FR 8810 - Gulf of Mexico Fishery Management Council; Public Meetings

    Science.gov (United States)

    2012-02-15

    .... SUMMARY: The Gulf of Mexico Fishery Management Council (Council) will convene its Law Enforcement Advisory... East Beach Blvd., Gulfport, MS 39501. Council address: Gulf of Mexico Fishery Management Council, 2203..., Deputy Executive Director, Gulf of Mexico Fishery Management Council; telephone: (813) 348-1630...

  16. 75 FR 7444 - Gulf of Mexico Fishery Management Council; Public Meetings

    Science.gov (United States)

    2010-02-19

    .... SUMMARY: The Gulf of Mexico Fishery Management Council (Council) will convene its Law Enforcement Advisory...., Orange Beach, AL 36561. Council address: Gulf of Mexico Fishery Management Council, 2203 North Lois... Director, Gulf of Mexico Fishery Management Council; telephone: (813) 348-1630. SUPPLEMENTARY INFORMATION...

  17. Recruitment of childhood leukaemia patients to clinical trials in Great Britain during 1980-2007: variation by birth weight, congenital malformation, socioeconomic status and ethnicity.

    Science.gov (United States)

    Shah, Anjali; Diggens, Nicole; Stiller, Charles; Richards, Sue; Stevens, Michael C G; Murphy, Michael F G

    2014-05-01

    To assess recruitment of children to national clinical trials for acute lymphoblastic leukaemia (ALL) and acute myeloid leukaemia (AML) in Great Britain during 1980-2007 and describe variation by some factors that might influence trial entry. Records of leukaemia patients aged 0-14 years at diagnosis were identified in the National Registry of Childhood Tumours and linked to birth registrations, Children's Cancer and Leukaemia Group records, Hospital Episode Statistics and Medical Research Council clinical trial registers. Trial entry rates were compared between categories of birth weight, congenital malformation, socioeconomic status and ethnicity. 9147 ALL and 1466 AML patients were eligible for national clinical trials during 1980-2007. Overall recruitment rates were 81% and 60% respectively. For ALL, rates varied significantly with congenital malformation (Down syndrome 61%, other malformations 80%, none 82%; p4000 g 67%; p=0.001) and congenital malformation (Down syndrome 28%, other malformations 56%, none 63%; pcongenital malformations.

  18. 77 FR 61466 - National Women's Business Council

    Science.gov (United States)

    2012-10-09

    ... SMALL BUSINESS ADMINISTRATION National Women's Business Council AGENCY: U.S. Small Business... Business Council (NWBC). The meeting will be open to the public. DATES: The meeting will be held on October... [[Page 61467

  19. 78 FR 25955 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-05-03

    ... Pacific Fishery Management Council's (Pacific Council) Highly Migratory Species Management Team (HMSMT... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... be implemented pursuant to the precautionary management framework for North Pacific albacore...

  20. 78 FR 27367 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-05-10

    ... Pacific Fishery Management Council's (Pacific Council) Highly Migratory Species Management Team (HMSMT... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... be implemented pursuant to the precautionary management framework for North Pacific albacore...

  1. 78 FR 70571 - Advisory Council on Wildlife Trafficking; Rescheduled Meeting

    Science.gov (United States)

    2013-11-26

    ... Advisory Council on Wildlife Trafficking (Council) will hold a meeting to discuss committee structure and organization, the National Strategy to Combat Wildlife Trafficking, and other council business as appropriate... Council organization and process, 2. The National Strategy to Combat Wildlife Trafficking, and 3. Other...

  2. Importance of mixed methods in pragmatic trials and dissemination and implementation research.

    Science.gov (United States)

    Albright, Karen; Gechter, Katherine; Kempe, Allison

    2013-01-01

    With increased attention to the importance of translating research to clinical practice and policy, recent years have seen a proliferation of particular types of research, including pragmatic trials and dissemination and implementation research. Such research seeks to understand how and why interventions function in real-world settings, as opposed to highly controlled settings involving conditions not likely to be repeated outside the research study. Because understanding the context in which interventions are implemented is imperative for effective pragmatic trials and dissemination and implementation research, the use of mixed methods is critical to understanding trial results and the success or failure of implementation efforts. This article discusses a number of dimensions of mixed methods research, utilizing at least one qualitative method and at least one quantitative method, that may be helpful when designing projects or preparing grant proposals. Although the strengths and emphases of qualitative and quantitative approaches differ substantially, methods may be combined in a variety of ways to achieve a deeper level of understanding than can be achieved by one method alone. However, researchers must understand when and how to integrate the data as well as the appropriate order, priority, and purpose of each method. The ability to demonstrate an understanding of the rationale for and benefits of mixed methods research is increasingly important in today's competitive funding environment, and many funding agencies now expect applicants to include mixed methods in proposals. The increasing demand for mixed methods research necessitates broader methodological training and deepened collaboration between medical, clinical, and social scientists. Although a number of challenges to conducting and disseminating mixed methods research remain, the potential for insight generated by such work is substantial. Copyright © 2013 Academic Pediatric Association. Published by

  3. 77 FR 9897 - Gulf of Mexico Fishery Management Council; Public Meetings

    Science.gov (United States)

    2012-02-21

    .... SUMMARY: The Gulf of Mexico Fishery Management Council (Council) will convene its Special Coral Scientific... Mexico Fishery Management Council; Public Meetings AGENCY: National Marine Fisheries Service (NMFS... Management Council, 2203 N. Lois Avenue, Suite 1100, Tampa, FL 33607. Council address: Gulf of Mexico Fishery...

  4. 78 FR 33070 - Gulf of Mexico Fishery Management Council; Public Meetings

    Science.gov (United States)

    2013-06-03

    .... SUMMARY: The Gulf of Mexico Fishery Management Council (Council) will convene a public meeting. DATES: The...; telephone: (850) 433-3336. Council address: Gulf of Mexico Fishery Management Council, 2203 North Lois... Director, Gulf of Mexico Fishery Management Council; telephone: (813) 348-1630. SUPPLEMENTARY INFORMATION...

  5. 78 FR 48419 - Mid-Atlantic Fishery Management Council (MAFMC); Public Meeting

    Science.gov (United States)

    2013-08-08

    ...: The Mid-Atlantic Fishery Management Council's (Council) Bluefish Advisory Panel (AP) will meet to develop a Fishery Performance Report for the Bluefish fishery in preparation for the Council and the... Council address below. Webinar link: http://mafmc.adobeconnect.com/bluefish/ Council address: Mid-Atlantic...

  6. The Globalization of Pediatric Research: An Analysis of Clinical Trials Completed for Pediatric Exclusivity

    Science.gov (United States)

    Pasquali, Sara K.; Burstein, Danielle S.; Benjamin, Daniel K.; Smith, P. Brian; Li, Jennifer S.

    2010-01-01

    Background Recent studies have examined the globalization of clinical research. These studies focused on adult trials, and the globalization of pediatric research has not been examined to date. We evaluated the setting of published studies conducted under the US Pediatric Exclusivity Program, which provides economic incentives to pharmaceutical companies to conduct drug studies in children. Methods Published studies containing the main results of trials conducted from 1998–2007 under the Pediatric Exclusivity Provision were included. Data were extracted from each study and described, including the therapeutic area of drug studied, number of patients enrolled, number of sites, and location where the study was conducted, if reported. Results Overall, 174 trials were included (sample size 8–27,065 patients); 9% did not report any information regarding the location or number of sites where the study was conducted. Of those that did report this information, 65% were conducted in at least one country outside the US, and 11% did not have any sites in the US. Fifty-four different countries were represented and 38% of trials enrolled patients in at least one site located in a developing/transition country, including more than one third of infectious disease, cardiovascular, and allergy/immunology trials. Conclusions The majority of published pediatric trials conducted under the Pediatric Exclusivity Provision included sites outside of the US, and over a third of trials enrolled patients in developing/transition countries. While there are many potential benefits to the globalization of pediatric research, this trend also raises certain scientific and ethical concerns which require further evaluation. PMID:20732941

  7. ITER council proceedings: 1997

    International Nuclear Information System (INIS)

    1997-01-01

    This volume of the ITER EDA Documentation Series presents records of the 12th ITER Council Meeting, IC-12, which took place on 23-24 July, 1997 in Tampere, Finland. The Council received from the Parties (EU, Japan, Russia, US) positive responses on the Detailed Design Report. The Parties stated their willingness to contribute to fulfil their obligations in contributing to the ITER EDA. The summary discussions among the Parties led to the consensus that in July 1998 the ITER activities should proceed for additional three years with a general intent to enable an efficient start of possible, future ITER construction

  8. 78 FR 56659 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-09-13

    ... Pacific Fishery Management Council's (Pacific Council) Groundfish Management Team (GMT) will hold a... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National...-16 groundfish harvest specifications and management measures, long-term impact analysis, and...

  9. Report on the proposal for a Council directive (EURATOM) on the management of spent nuclear fuel and radioactive waste - Committee on Industry, External Trade, Research and Energy

    International Nuclear Information System (INIS)

    2006-01-01

    By letter of 13 May 2003 the Council consulted Parliament, pursuant to Articles 31 and 32 of the EURATOM Treaty, on the proposal for a Council directive (EURATOM) on the management of spent nuclear fuel and radioactive waste (COM(2003) 32 - 2003/0022(CNS)). At the sitting of 15 May 2003 the President of Parliament announced that he had referred the proposal to the Committee on Industry, External Trade, Research and Energy as the committee responsible and the Committee on the Environment, Public Health and Consumer Policy for its opinion (C5-0229/2003). The Committee on Industry, External Trade, Research and Energy appointed Alejo Vidal-Quadras Roca Rapporteur at its meeting of 22 May 2003. The committee considered the Commission proposal and draft report at its meetings of 9 July, 9 September, 6 October, 3 November and 27 November 2003. At the last meeting it adopted the draft legislative resolution by 36 votes to 7, with 2 abstentions. The opinion of the Committee on the Environment, Public Health and Consumer Policy is attached. The report was tabled on 1 December 2003

  10. National Council on Alcoholism and Drug Dependence

    Science.gov (United States)

    ... Month NCADD National Council on Alcoholism and Drug Dependence Addiction is a Disease - Treatment is Available - Recovery ... years, The National Council on Alcoholism and Drug Dependence, Inc. (NCADD) has been a valuable resource for ...

  11. 78 FR 49728 - Availability of Seats for National Marine Sanctuary Advisory Councils

    Science.gov (United States)

    2013-08-15

    ...: Fishing (primary member); Fishing (alternate); and Education (alternate). Florida Keys National Marine... (primary member); Research and Monitoring (alternate); Tourism--Lower Keys (primary member); and Tourism--Lower Keys (alternate). Gulf of the Farallones National Marine Sanctuary Advisory Council: Education...

  12. 75 FR 20985 - North Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-04-22

    .... SUMMARY: The North Pacific Fishery Management Council's Crab Plan Team (CPT) will meet in Alaska on May 10... Pacific Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS... Room - May 14. Council address: North Pacific Fishery Management Council, 605 W. 4th Avenue, Suite 306...

  13. 76 FR 36930 - National Advisory Council on Alcohol Abuse and Alcoholism and National Advisory Council on Drug...

    Science.gov (United States)

    2011-06-23

    ... Alcohol Abuse and Alcoholism and National Advisory Council on Drug Abuse; Notice of Joint Meeting Pursuant... given of a joint meeting of the National Advisory Council on Alcohol Abuse and Alcoholism and the National Institute on Drug Abuse. The meeting will be open to the public as indicated below, with...

  14. Design of the Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial.

    Science.gov (United States)

    Bradford, Andrew; Lees, Kennedy

    2000-01-01

    The Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial is a multicentre,randomised, placebo-controlled trial of magnesium sulphate (MgSO4) funded by the UK Medical Research Council. When complete, it will be the largest single neuroprotective study undertaken to date. Conscious patients presenting within 12 h of acute stroke with limb weakness are eligible. The primary outcome measure is combined death and disability as measured using the Barthel Index at 90-day follow up. By randomizing 2700 patients, the study will have 84% power to detect a 5.5% absolute reduction in the primary end-point. By April 2000, 86 centres were participating, with representation in Canada, USA, Europe, South America, Singapore and Australia. So far, 1206 patients have been randomised, of whom 37% were treated within 6 h. Overall 3-month mortality was 20% and the primary outcome event rate was 43%. The study is ongoing and centres worldwide are encouraged to participate.

  15. Telemedicine Provides Non-Inferior Research Informed Consent for Remote Study Enrollment: A Randomized Controlled Trial

    Science.gov (United States)

    Bobb, Morgan R.; Van Heukelom, Paul G.; Faine, Brett A.; Ahmed, Azeemuddin; Messerly, Jeffrey T.; Bell, Gregory; Harland, Karisa K.; Simon, Christian; Mohr, Nicholas M.

    2016-01-01

    Objective Telemedicine networks are beginning to provide an avenue for conducting emergency medicine research, but using telemedicine to recruit participants for clinical trials has not been validated. The goal of this consent study is to determine whether patient comprehension of telemedicine-enabled research informed consent is non-inferior to standard face-to-face research informed consent. Methods A prospective, open-label randomized controlled trial was performed in a 60,000-visit Midwestern academic Emergency Department (ED) to test whether telemedicine-enabled research informed consent provided non-inferior comprehension compared with standard consent. This study was conducted as part of a parent clinical trial evaluating the effectiveness of oral chlorhexidine gluconate 0.12% in preventing hospital-acquired pneumonia among adult ED patients with expected hospital admission. Prior to being recruited into the study, potential participants were randomized in a 1:1 allocation ratio to consent by telemedicine versus standard face-to-face consent. Telemedicine connectivity was provided using a commercially available interface (REACH platform, Vidyo Inc., Hackensack, NJ) to an emergency physician located in another part of the ED. Comprehension of research consent (primary outcome) was measured using the modified Quality of Informed Consent (QuIC) instrument, a validated tool for measuring research informed consent comprehension. Parent trial accrual rate and qualitative survey data were secondary outcomes. Results One-hundred thirty-one patients were randomized (n = 64, telemedicine), and 101 QuIC surveys were completed. Comprehension of research informed consent using telemedicine was not inferior to face-to-face consent (QuIC scores 74.4 ± 8.1 vs. 74.4 ± 6.9 on a 100-point scale, p = 0.999). Subjective understanding of consent (p=0.194) and parent trial study accrual rates (56% vs. 69%, p = 0.142) were similar. Conclusion Telemedicine is non-inferior to face

  16. 75 FR 55745 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-09-14

    ... Pacific Fishery Management Council's (Pacific Council) Coastal Pelagic Species Management Team (CPSMT) and... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... sardine stock assessment for 2010. Other issues relevant to Coastal Pelagic Species fisheries management...

  17. 78 FR 77658 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-12-24

    ... Pacific Fishery Management Council's (Pacific Council) Highly Migratory Species Management Team (HMSMT... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National.... Potential changes to management measures for the west coast drift gillnet fishery. 2. Developments to...

  18. 75 FR 7444 - Gulf of Mexico Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-02-19

    .... SUMMARY: The Gulf of Mexico Fishery Management Council (Council) will convene a web based meeting of the... via internet. Please go to the Gulf of Mexico Fishery Management Council's website at www.gulfcouncil.org for instructions. Council address: Gulf of Mexico Fishery Management Council, 2203 N. Lois Avenue...

  19. Physician participation in clinical research and trials: issues and approaches

    Directory of Open Access Journals (Sweden)

    Sami F Shaban

    2011-03-01

    research culture’. This article examines the barriers to and benefits of physician participation in clinical research as well as interventions needed to increase their participation, including the specific role of undergraduate medical education. The main challenge is the unwillingness of many physicians and patients to participate in clinical trials. Barriers to participation include lack of time, lack of resources, trial-specific issues, communication difficulties, conflicts between the role of clinician and scientist, inadequate research experience and training for physicians, lack of rewards and recognition for physicians, and sometimes a scientifically uninteresting research question, among others. Strategies to encourage physician participation in clinical research include financial and nonfinancial incentives, adequate training, research questions that are in line with physician interests and have clear potential to improve patient care, and regular feedback. Finally, encouraging research culture and fostering the development of inquiry and research-based learning among medical students is now a high priority in order to develop more and better clinician-researchers.Keywords: physician, clinical research, clinical trial, medical education

  20. 77 FR 60380 - Caribbean Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-10-03

    ... Caribbean Fishery Management Council's Scientific and Statistical Committee (SSC) will hold meetings. DATES... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... CONTACT: Caribbean Fishery Management Council, 268 Mu[ntilde]oz Rivera Avenue, Suite 1108, San Juan...

  1. 75 FR 971 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-01-07

    ... Pacific Fishery Management Council's (Council) Scientific and Statistical Committee, Coastal Pelagic Species Management Team, and Groundfish Management Team will hold a working meeting, which is open to the... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National...

  2. 77 FR 45591 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-08-01

    ... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... Pacific Fishery Management Council's (Pacific Council) Ad Hoc South of Humbug Pacific Halibut Workgroup..., monitoring, and allocation history of Pacific halibut in the area south of Humbug Mt. DATES: The conference...

  3. 76 FR 2672 - Caribbean Fishery Management Council; Public Meeting

    Science.gov (United States)

    2011-01-14

    ... Caribbean Fishery Management Council (Council) in partnership with the Fisheries Leadership and... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... Management of Data Poor Stocks.'' The intent of this workshop is to discuss tools that the region may find...

  4. 76 FR 1628 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2011-01-11

    ...] Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife Service, Interior. ACTION... teleconference of the Sport Fishing and Boating Partnership Council (Council). DATE(S): We will hold the... sport fishing, boating, and conservation communities and is organized to enhance partnerships among...

  5. Clinical trial network for the promotion of clinical research for rare diseases in Japan: muscular dystrophy clinical trial network.

    Science.gov (United States)

    Shimizu, Reiko; Ogata, Katsuhisa; Tamaura, Akemi; Kimura, En; Ohata, Maki; Takeshita, Eri; Nakamura, Harumasa; Takeda, Shin'ichi; Komaki, Hirofumi

    2016-07-11

    Duchenne muscular dystrophy (DMD) is the most commonly inherited neuromuscular disease. Therapeutic agents for the treatment of rare disease, namely "orphan drugs", have recently drawn the attention of researchers and pharmaceutical companies. To ensure the successful conduction of clinical trials to evaluate novel treatments for patients with rare diseases, an appropriate infrastructure is needed. One of the effective solutions for the lack of infrastructure is to establish a network of rare diseases. To accomplish the conduction of clinical trials in Japan, the Muscular dystrophy clinical trial network (MDCTN) was established by the clinical research group for muscular dystrophy, including the National Center of Neurology and Psychiatry, as well as national and university hospitals, all which have a long-standing history of research cooperation. Thirty-one medical institutions (17 national hospital organizations, 10 university hospitals, 1 national center, 2 public hospitals, and 1 private hospital) belong to this network and collaborate to facilitate clinical trials. The Care and Treatment Site Registry (CTSR) calculates and reports the proportion of patients with neuromuscular diseases in the cooperating sites. In total, there are 5,589 patients with neuromuscular diseases in Japan and the proportion of patients with each disease is as follows: DMD, 29 %; myotonic dystrophy type 1, 23 %; limb girdle muscular dystrophy, 11 %; Becker muscular dystrophy, 10 %. We work jointly to share updated health care information and standardized evaluations of clinical outcomes as well. The collaboration with the patient registry (CTSR), allows the MDCTN to recruit DMD participants with specific mutations and conditions, in a remarkably short period of time. Counting with a network that operates at a national level is important to address the corresponding national issues. Thus, our network will be able to contribute with international research activity, which can lead to

  6. Accounting and Accountability by Provincial Councils in Fiji: the Case of Namosi

    Directory of Open Access Journals (Sweden)

    Nacanieli Rika

    2008-03-01

    Full Text Available The aim of this paper is twofold: firstly to examine how the concepts of accounting andaccountability are understood by indigenous Fijians; and secondly to examine the role ofaccounting in the accountability of provincial councils.Provincial councils are part of the Fijian Administration, which runs alongside the centralgovernment but applies only to indigenous Fijians. The Fijian Administration was introducedby the British colonial administration in the late 1800s as a mechanism for controllingindigenous Fijians. It has undergone several reviews resulting from criticisms that it has failedto fulfill the aspirations of indigenous Fijians.There is evidence of implied and actual accountability by indigenous Fijians in Namosi. Thisis supported by monitoring mechanisms established by provincial offices. On the other hand,neither the Fijian Affairs Board nor the Namosi Provincial Council appears to take seriousresponsibility for accounting to indigenous Fijians in the province. Sadly, there is littleevidence to demonstrate an explicit accountability to indigenous Fijians. Significant scopeexists for improving the standard of accounting and accountability by provincial councils.This study contributes to understanding the role of accounting among indigenous peoples, inthe context of inherited colonial structures. It also represents accounting research conductedby indigenous academics, primarily in the Fijian language. This enables an examination ofhow language frames understanding of accounting concepts.

  7. Highlights: Spring Council Meeting

    Science.gov (United States)

    Council members present at the May 24, 1981, meeting were Keiiti Aki, Steven Burges (for Jim Wallis), Peter S. Eagleson, E. R. Engdahl, Charles E. Helsley, James R. Heirtzler, Carl Kisslinger, Leslie H. Meredith, Chris N. K. Mooers, Norman F. Ness, Marcia M. Neugebauer, James J. O'Brien, Richard Rapp, Carl Sagan, James C. Savage, Joseph V. Smith, Fred Spilhaus, Donald L. Turcotte, James A. Van Allen, J. Tuzo Wilson, and Jay Winston (for Elmar R. Reiter until his arrival at 6:50 P.M.). David Strangway, representing the Canadian Geophysical Union, and Peter Steinhauser, representing the European Geophysical Society, were special observers at the meeting. Council meetings are open, and a number of section secretaries, committee chairmen, journal editors, and other members attended. The following major actions were adopted by the Council:The experiment of publishing oceanography and lower-atmosphere papers in JGR Green issues alternate to those containing upper-atmosphere papers will be continued through 1982. From preliminary indications the experiment seems to be working, but a full year of data, including a renewal cycle, is needed to assess the success of the experiment. Final decision will be made prior to the 1983 dues notices.

  8. Clinical Trials

    Medline Plus

    Full Text Available ... Clinical Trials About Clinical Trials Clinical trials are research studies that explore whether a medical strategy, treatment, or ... humans. What Are Clinical Trials? Clinical trials are research studies that explore whether a medical strategy, treatment, or ...

  9. 10 March 2008 - Swedish Minister for Higher Education and Research L. Leijonborg signing the guest book with CERN Chef Scientific Officer J. Engelen, followed by the signature of the Swedish Computing Memorandum of Understanding by the Director General of the Swedish Research Council P. Ömling.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    10 March 2008 - Swedish Minister for Higher Education and Research L. Leijonborg signing the guest book with CERN Chef Scientific Officer J. Engelen, followed by the signature of the Swedish Computing Memorandum of Understanding by the Director General of the Swedish Research Council P. Ömling.

  10. Predictors of Missed Research Appointments in a Randomized Placebo-Controlled Trial

    Directory of Open Access Journals (Sweden)

    Stéphanie J.E. Becker

    2014-09-01

     Younger patients with no college education, who believe their health can be controlled, are more likely to miss a research appointment when enrolled in a randomized placebo injection-controlled trial

  11. 75 FR 59747 - NASA Advisory Council; Meeting.

    Science.gov (United States)

    2010-09-28

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice: (10-113)] NASA Advisory Council; Meeting. AGENCY: National Aeronautics and Space Administration. ACTION: Notice of meeting. SUMMARY: In accordance... Space Administration announces a meeting of the NASA Advisory Council. DATES: Wednesday, October 6, 2010...

  12. Inside Student Government: The Variable Quality of High School Student Councils

    Science.gov (United States)

    McFarland, Daniel; Starmanns, Carlos E.

    2009-01-01

    Background/Context: Student governments are the first direct experience that youth have of representative government. However, very little research has been done on student councils in spite of their ubiquity in American high schools and consistent references to their positive effects on the political socialization of youth.…

  13. 76 FR 81959 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2011-12-29

    ...] Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife Service, Interior. ACTION... Sport Fishing and Boating Partnership Council (Council). DATES: The meeting will be held on Wednesday... requirements of the Federal Advisory Committee Act, 5 U.S.C. App., we announce that the Sport Fishing and...

  14. 77 FR 26784 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2012-05-07

    ...-FVWF979209000005D-XXX] Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife Service, Interior... public teleconference of the Sport Fishing and Boating Partnership Council (Council). DATES... accordance with the requirements of the Federal Advisory Committee Act, 5 U.S.C. App., we announce that Sport...

  15. 78 FR 4161 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2013-01-18

    ...-FVWF97920900000-XXX] Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife Service, Interior... public teleconference of the Sport Fishing and Boating Partnership Council (Council). DATES... accordance with the requirements of the Federal Advisory Committee Act, 5 U.S.C. App., we announce that Sport...

  16. 2011 Elections to Staff Council

    CERN Multimedia

    Staff Association

    2011-01-01

    Vote Elections to fill all seats in the Staff Council are being organized this month. Voting will begin on Monday 31 October. Make your voice heard and be many to elect the new Staff Council. By doing so, you will be encouraging the men and women who will  represent you over the next two years and they will doubtless appreciate your gratitude. More details on the elections can be found on the Staff Association web site. (http://association.web.cern.ch) Elections Timetable Monday 31 October, at noon start date for voting Monday 14 November, at noon closing date for voting Monday 21 November, publication of the results in Echo Tuesday 22 and Wednesday 29 November Staff Association Assizes Tuesday 6 December, at 10.00 a.m. first meeting of the new Staff Council and election of the new Executive Committee The voting procedure is monitored by the Election Committee. 

  17. 78 FR 23587 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2013-04-19

    ...-FVWF97920900000-XXX] Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife Service, Interior... meeting of the Sport Fishing and Boating Partnership Council (Council). A Federal advisory committee, the... the Federal Advisory Committee Act, 5 U.S.C. App., we announce that the Sport Fishing and Boating...

  18. For an alliance between science, ethics and politics in promoting paediatric trials. Commentary.

    Science.gov (United States)

    Petrini, Carlo; Rana, Ippolita; Alleva, Enrico

    2016-01-01

    After several decades during which children tended to be excluded from clinical trials, provisions to encourage trials with children have been in place for some years both at international level and in individual countries. The Nuffield Council on Bioethics has published a broad-ranging report on the subject, which makes concrete proposals for decision-makers and comes at a crucial moment in the definition of European Union regulations on this topic.

  19. Assessing the impact of user-centered research on a clinical trial eHealth tool via counterbalanced research design.

    Science.gov (United States)

    Atkinson, Nancy L; Massett, Holly A; Mylks, Christy; McCormack, Lauren A; Kish-Doto, Julia; Hesse, Bradford W; Wang, Min Qi

    2011-01-01

    Informatics applications have the potential to improve participation in clinical trials, but their design must be based on user-centered research. This research used a fully counterbalanced experimental design to investigate the effect of changes made to the original version of a website, http://BreastCancerTrials.org/, and confirm that the revised version addressed and reinforced patients' needs and expectations. Participants included women who had received a breast cancer diagnosis within the last 5 years (N=77). They were randomized into two groups: one group used and reviewed the original version first followed by the redesigned version, and the other group used and reviewed them in reverse order. The study used both quantitative and qualitative measures. During use, participants' click paths and general reactions were observed. After use, participants were asked to answer survey items and open-ended questions to indicate their reactions and which version they preferred and met their needs and expectations better. Overall, the revised version of the site was preferred and perceived to be clearer, easier to navigate, more trustworthy and credible, and more private and safe overall. However, users who viewed the original version last had similar attitudes toward both versions. By applying research findings to the redesign of a website for clinical trial searching, it was possible to re-engineer the interface to better support patients' decisions to participate in clinical trials. The mechanisms of action in this case appeared to revolve around creating an environment that supported a sense of personal control and decisional autonomy.

  20. 75 FR 78875 - White House Council for Community Solutions

    Science.gov (United States)

    2010-12-17

    ... Order 13560 of December 14, 2010 White House Council for Community Solutions By the authority vested in... White House Council for Community Solutions (Council) within the Corporation for National and Community.... (Presidential Sig.) THE WHITE HOUSE, December 14, 2010. [FR Doc. 2010-31878 Filed 12-16-10; 8:45 am] Billing...

  1. 77 FR 29359 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2012-05-17

    ...-FVWF979209000005D-XXX] Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife Service, Interior... meeting of the Sport Fishing and Boating Partnership Council (Council). A Federal advisory committee, the... requirements of the Federal Advisory Committee Act, 5 U.S.C. App., we announce that the Sport Fishing and...

  2. 20 CFR 628.210 - State Job Training Coordinating Council.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false State Job Training Coordinating Council. 628... PROGRAMS UNDER TITLE II OF THE JOB TRAINING PARTNERSHIP ACT State Planning § 628.210 State Job Training Coordinating Council. (a) The Governor shall appoint a State Job Training Coordinating Council (SJTCC) pursuant...

  3. 78 FR 23223 - Mid-Atlantic Fishery Management Council (MAFMC); Public Meeting

    Science.gov (United States)

    2013-04-18

    .... SUMMARY: The Scientific and Statistical Committee (SSC) of the Mid- Atlantic Fishery Management Council... Fishery Management Council (MAFMC); Public Meeting AGENCY: National Marine Fisheries Service (NMFS...: (410) 522-7377. Council address: Mid-Atlantic Fishery Management Council, 800 N. State Street, Suite...

  4. 77 FR 76473 - Gulf of Mexico Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-12-28

    ... Management Council (Council) will convene the Socioeconomic Scientific and Statistical Committee (SSC) to... Mexico Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS... meeting. SUMMARY: The Gulf of Mexico Fishery Management Council will convene a meeting of the...

  5. 78 FR 21915 - Mid-Atlantic Fishery Management Council (MAFMC); Public Meeting

    Science.gov (United States)

    2013-04-12

    .... SUMMARY: The Scientific and Statistical Committee (SSC) of the Mid- Atlantic Fishery Management Council... Fishery Management Council (MAFMC); Public Meeting AGENCY: National Marine Fisheries Service (NMFS...://www.mafmc.org . Council address: Mid-Atlantic Fishery Management Council, 800 North State Street...

  6. 78 FR 53731 - Mid-Atlantic Fishery Management Council (MAFMC); Public Meeting

    Science.gov (United States)

    2013-08-30

    ...: The Scientific and Statistical Committee (SSC) of the Mid- Atlantic Fishery Management Council... Fishery Management Council (MAFMC); Public Meeting AGENCY: National Marine Fisheries Service (NMFS..., MD 21231, telephone: (410) 522-7380. Council address: Mid-Atlantic Fishery Management Council, 800 N...

  7. 76 FR 7869 - Notice of Meeting; Advisory Council on Historic Preservation

    Science.gov (United States)

    2011-02-11

    ... ADVISORY COUNCIL ON HISTORIC PRESERVATION Notice of Meeting; Advisory Council on Historic Preservation AGENCY: Advisory Council on Historic Preservation. ACTION: Notice of Meeting. Summary: Notice is hereby given that the Advisory Council on Historic Preservation (ACHP) will meet Thursday, February 17...

  8. 75 FR 71135 - Notice of Meeting; Advisory Council on Historic Preservation

    Science.gov (United States)

    2010-11-22

    ... ADVISORY COUNCIL ON HISTORIC PRESERVATION Notice of Meeting; Advisory Council on Historic Preservation AGENCY: Advisory Council on Historic Preservation. ACTION: Notice of meeting. SUMMARY: Notice is hereby given that the Advisory Council on Historic Preservation (ACHP) will meet Thursday, December 2...

  9. 78 FR 41804 - NASA Advisory Council; Meeting.

    Science.gov (United States)

    2013-07-11

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice: (13-077)] NASA Advisory Council; Meeting... Space Administration announces a meeting of the NASA Advisory Council (NAC). DATES: Wednesday, July 31... ADDRESSES: NASA Headquarters, Room 9H40, Program Review Center, 300 E Street SW., Washington, DC 20456 FOR...

  10. 78 FR 61404 - Federal Salary Council; Meeting

    Science.gov (United States)

    2013-10-03

    ... OFFICE OF PERSONNEL MANAGEMENT Federal Salary Council; Meeting AGENCY: Office of Personnel Management. ACTION: Notice of meeting. SUMMARY: The Federal Salary Council will meet on November 5, 2013, at... recommendations cover the establishment or modification of locality pay areas, the coverage of salary surveys, the...

  11. 75 FR 63215 - Federal Salary Council Meeting

    Science.gov (United States)

    2010-10-14

    ... OFFICE OF PERSONNEL MANAGEMENT Federal Salary Council Meeting AGENCY: Office of Personnel Management. ACTION: Notice of Meeting. SUMMARY: The Federal Salary Council will meet on October 29, 2010, at... recommendations cover the establishment or modification of locality pay areas, the coverage of salary surveys, the...

  12. 76 FR 59175 - Federal Salary Council; Meeting

    Science.gov (United States)

    2011-09-23

    ... OFFICE OF PERSONNEL MANAGEMENT Federal Salary Council; Meeting AGENCY: Office of Personnel Management. ACTION: Notice of meeting. SUMMARY: The Federal Salary Council will meet on November 4, 2011, at... recommendations cover the establishment or modification of locality pay areas, the coverage of salary surveys, the...

  13. 76 FR 21786 - National Women's Business Council

    Science.gov (United States)

    2011-04-18

    ... SMALL BUSINESS ADMINISTRATION National Women's Business Council AGENCY: U.S. Small Business... Business Council (NWBC). The meeting will be open to the public. DATES: The meeting will be held on April... Russell Senate Office Building (U.S. Senate Committee on Small Business and Entrepreneurship), Washington...

  14. Using the Medical Research Council framework for development and evaluation of complex interventions in a low resource setting to develop a theory-based treatment support intervention delivered via SMS text message to improve blood pressure control.

    Science.gov (United States)

    Bobrow, Kirsten; Farmer, Andrew; Cishe, Nomazizi; Nwagi, Ntobeko; Namane, Mosedi; Brennan, Thomas P; Springer, David; Tarassenko, Lionel; Levitt, Naomi

    2018-01-23

    Several frameworks now exist to guide intervention development but there remains only limited evidence of their application to health interventions based around use of mobile phones or devices, particularly in a low-resource setting. We aimed to describe our experience of using the Medical Research Council (MRC) Framework on complex interventions to develop and evaluate an adherence support intervention for high blood pressure delivered by SMS text message. We further aimed to describe the developed intervention in line with reporting guidelines for a structured and systematic description. We used a non-sequential and flexible approach guided by the 2008 MRC Framework for the development and evaluation of complex interventions. We reviewed published literature and established a multi-disciplinary expert group to guide the development process. We selected health psychology theory and behaviour change techniques that have been shown to be important in adherence and persistence with chronic medications. Semi-structured interviews and focus groups with various stakeholders identified ways in which treatment adherence could be supported and also identified key features of well-regarded messages: polite tone, credible information, contextualised, and endorsed by identifiable member of primary care facility staff. Direct and indirect user testing enabled us to refine the intervention including refining use of language and testing of interactive components. Our experience shows that using a formal intervention development process is feasible in a low-resource multi-lingual setting. The process enabled us to pre-test assumptions about the intervention and the evaluation process, allowing the improvement of both. Describing how a multi-component intervention was developed including standardised descriptions of content aimed to support behaviour change will enable comparison with other similar interventions and support development of new interventions. Even in low

  15. 77 FR 55192 - Mid-Atlantic Fishery Management Council (MAFMC); Public Meeting

    Science.gov (United States)

    2012-09-07

    .... SUMMARY: The Scientific and Statistical Committee (SSC) of the Mid- Atlantic Fishery Management Council... Fishery Management Council (MAFMC); Public Meeting AGENCY: National Marine Fisheries Service (NMFS.... Council address: Mid-Atlantic Fishery Management Council, 800 N. State Street, Suite 201, Dover, DE 19901...

  16. Theory of Change: a theory-driven approach to enhance the Medical Research Council's framework for complex interventions

    Science.gov (United States)

    2014-01-01

    Background The Medical Research Councils’ framework for complex interventions has been criticized for not including theory-driven approaches to evaluation. Although the framework does include broad guidance on the use of theory, it contains little practical guidance for implementers and there have been calls to develop a more comprehensive approach. A prospective, theory-driven process of intervention design and evaluation is required to develop complex healthcare interventions which are more likely to be effective, sustainable and scalable. Methods We propose a theory-driven approach to the design and evaluation of complex interventions by adapting and integrating a programmatic design and evaluation tool, Theory of Change (ToC), into the MRC framework for complex interventions. We provide a guide to what ToC is, how to construct one, and how to integrate its use into research projects seeking to design, implement and evaluate complex interventions using the MRC framework. We test this approach by using ToC within two randomized controlled trials and one non-randomized evaluation of complex interventions. Results Our application of ToC in three research projects has shown that ToC can strengthen key stages of the MRC framework. It can aid the development of interventions by providing a framework for enhanced stakeholder engagement and by explicitly designing an intervention that is embedded in the local context. For the feasibility and piloting stage, ToC enables the systematic identification of knowledge gaps to generate research questions that strengthen intervention design. ToC may improve the evaluation of interventions by providing a comprehensive set of indicators to evaluate all stages of the causal pathway through which an intervention achieves impact, combining evaluations of intervention effectiveness with detailed process evaluations into one theoretical framework. Conclusions Incorporating a ToC approach into the MRC framework holds promise for

  17. 76 FR 37873 - National Women's Business Council

    Science.gov (United States)

    2011-06-28

    ... SMALL BUSINESS ADMINISTRATION National Women's Business Council AGENCY: U.S. Small Business... National Women's Business Council (NWBC). The meeting will be open to the public. DATE: The meeting will be... p.m. EST. ADDRESSES: The meeting will be held at the U. S. Small Business Administration Building...

  18. The Transformative Impact of Undergraduate Research Mentoring on Students and the Role of the Council on Undergraduate Research (CUR) in Supporting Faculty Mentors

    Science.gov (United States)

    Fox, L. K.; Singer, J.

    2015-12-01

    Undergraduate Research (UR) is broadly accepted as a high impact educational practice. Student participation in UR contributes to measurable gains in content knowledge and skills/methodology, oral and written communication skills, problem solving and critical thinking, self-confidence, autonomy, among others. First-generation college students and students from underrepresented minorities that participate in UR are more likely to remain in STEM majors, persist to graduation, and pursue graduate degrees. While engagement in the research process contributes to these outcomes, the impact of the interaction with the faculty mentor is critical. A number of studies provide evidence that it is the relationship that forms with the faculty mentor that is most valued by students and strongly contributes to their career development. Faculty mentors play an important role in student development and the relationship between mentor and student evolves from teacher to coach to colleague. Effective mentoring is not an inherent skill and is generally not taught in graduate school and generally differs from mentoring of graduate students. Each UR mentoring relationship is unique and there are many effective mentoring models and practices documented in the literature. The Council on Undergraduate Research (CUR) has a long history of supporting faculty who engage in research with undergraduates and offers resources for establishing UR programs at individual, departmental, and institutional levels. The Geosciences Division of CUR leads faculty development workshops at professional meetings and provides extensive resources to support geosciences faculty as UR mentors (http://serc.carleton.edu/NAGTWorkshops/undergraduate_research/index.html). Examples of effective mentoring strategies are highlighted, including a model developed by SUNY- Buffalo State that integrates mentoring directly into the evaluation of UR.

  19. An Evaluation of The Decisions Taken About Psychological Counseling and Guidance in the Turkish National Education Councils (1939-2010

    Directory of Open Access Journals (Sweden)

    Fulya YÜKSEL-ŞAHİN

    2012-05-01

    Full Text Available The Purpose of the ResearchNumerous decisions regarding the psychological counseling and guidance (PCG services were taken during the Turkish National Education Councils (TNE Council, which convened eighteen times between 1939 and 2010. The present study evaluates the decisions made about the PCG services addressed in the TNE Councils held between 1939 and 2010. MethodThe study employed the case study design among qualitative research designs. Case study is an empirical research method that studies a contemporary phenomenon in its own real-life circumstances and makes a multidirectional, systematic, and in-depth examination of cases (Büyüköztürk, Kılıç-Çakmak, Akgün, Karadeniz ve Demirel, 2009. The study universe consists of the Turkish National Education Councils held between 1939 and 2010. No sampling was performed since the entire universe was available. The study employed the embedded singlecase design (type 2 among the case study designs. Written document analysis was used as the data collection method and the obtained data were analyzed through descriptive analysis. Furthermore, the data obtained from the documents are also presented in quantitative form. For this purpose, the “yes or no method” and the “covered area method” were used and frequency and percentage distributions are provided.

  20. 78 FR 42755 - Gulf of Mexico Fishery Management Council; Public Hearings

    Science.gov (United States)

    2013-07-17

    ...: The Gulf of Mexico Fishery Management Council (Council) will hold public hearings for Coastal... through Friday August 15, 2013 at ten locations throughout the Gulf of Mexico. The public hearings will...; Mobile, AL; Corpus Christi and Texas City, TX. Council address: Gulf of Mexico Fishery Management Council...

  1. Comparison between Radiology Science Laboratory, Brazil (LCR) and National Research Council, Canada (NRC) of the absorbed dose in water using Fricke dosimetry

    International Nuclear Information System (INIS)

    Salata, Camila; David, Mariano Gazineu; Almeida, Carlos Eduardo de

    2014-01-01

    The absorbed dose to water standards for HDR brachytherapy dosimetry developed by the Radiology Science Laboratory, Brazil (LCR) and the National Research Council, Canada (NRC), were compared. The two institutions have developed absorbed dose standards based on the Fricke dosimetry system. There are significant differences between the two standards as far as the preparation and readout of the Fricke solution and irradiation geometry of the holder. Measurements were done at the NRC laboratory using a single Ir-192 source. The comparison of absorbed dose measurements was expressed as the ratio Dw(NRC)/Dw(LCR), which was found to be 1.026. (author)

  2. Compliance revisited: pharmaceutical drug trials in the era of the contract research organization.

    Science.gov (United States)

    Jonvallen, Petra

    2009-12-01

    Over the past decade, the management of clinical trials of pharmaceuticals has become a veritable industry, as evidenced by the emergence and proliferation of contract research organizations (CROs) that co-ordinate and monitor trials. This article focuses on work performed by one CRO involved in the introduction of new software, modelled on industrial production processes, into clinical trial practices. It investigates how this new management technique relates to the work performed in the clinic to ensure that trial participants comply with the protocol. Using an analytical distinction between 'classical' management work and invisible work, the article contextualizes the meaning of compliance in the clinic and suggests that the work involved in producing compliance should be taken into consideration by those concerned with validity of trials, as clinical trials are put under private industrial management. The article builds on participant observation at a Swedish university hospital and interviews the nurses, dieticians, doctors and a software engineer, all part of a team involved in pharmaceutical drug trials on a potential obesity drug.

  3. 76 FR 4133 - NASA Advisory Council; Meeting

    Science.gov (United States)

    2011-01-24

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice: (11-007)] NASA Advisory Council; Meeting... Space Administration announces a meeting of the NASA Advisory Council. DATES: Thursday, February 10, 2011, 8 a.m.-5 p.m., Local Time. Friday, February 11, 2011, 8 a.m.-12 p.m., Local Time. ADDRESSES: NASA...

  4. 75 FR 5629 - NASA Advisory Council; Meeting

    Science.gov (United States)

    2010-02-03

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (10-019)] NASA Advisory Council; Meeting... Space Administration announces a meeting of the NASA Advisory Council. DATES: Thursday, February 18, 2010, 9 a.m.-5 p.m. EST; Friday, February 19, 2010, 9 a.m.-1 p.m., EST. ADDRESSES: NASA Headquarters...

  5. 75 FR 4875 - NASA Advisory Council; Meeting

    Science.gov (United States)

    2010-01-29

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (10-015)] NASA Advisory Council; Meeting... the NASA Advisory Council. This will be the first meeting of this Committee. DATES: February 17, 2010--10 a.m.-4 p.m. (EST). ADDRESSES: NASA Headquarters, 300 E Street, SW., Washington, DC, Room CD61. FOR...

  6. Generating solutions : summary of the Electricity Sector Council's review of foreign credential recognition

    International Nuclear Information System (INIS)

    2008-03-01

    The Electricity Sector Council has recognized the increasing requirement to recruit and retain internationally trained workers to offset the anticipated retirement of up to 40 per cent of skilled workers in this sector by 2014. This document provided a brief summary of the review of foreign credential recognition in Canada's Electricity Council which was prepared in February 2008. The purpose of the study was to capture a perceptive picture of Canada's electricity labour force and to assist the Electricity Sector Council in the potential development and implementation of strategies to facilitate the integration of internationally trained workers into Canada's electricity sector. This synopsis report presented the analysis of the study including a discussion of immigration trends; foreign credential recognition in Canada's electricity sector; immigration profiles by region; case study profiles; and recommendations. It was recommended that resources be researched, developed and provided in order to help stakeholders attract, recruit, retain and integrate internationally trained workers. 2 refs

  7. Evaluation of Carrying Capacity : Measure 7.1A of the Northwest Power Planning Council`s 1994 Fish and Wildlife Program : Report 1 of 4, Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    Neitzel, Duane A.; Johnson, Gary E.

    1996-05-01

    This report is one of four that the Pacific Northwest National Laboratory (PNNL) staff prepared to address Measure 7.1A in the Northwest Power Planning Council's (Council) Fish and Wildlife Program (Program) dated december 1994 (NPPC 1994). Measure 7.1A calls for the Bonneville Power Administration (BPA) to fund an evaluation of salmon survival, ecology, carrying capacity, and limiting factors in freshwater, estuarine, and marine habitats. Additionally, the Measure asks for development of a study plan based on critical uncertainties and research needs identified during the evaluation. This report deals with the evaluation of carrying capacity. It describes the analysis of different views of capacity as it relates to salmon survival and abundance. The report ends with conclusions and recommendations for studying carrying capacity.

  8. Priorities for methodological research on patient and public involvement in clinical trials: A modified Delphi process.

    Science.gov (United States)

    Kearney, Anna; Williamson, Paula; Young, Bridget; Bagley, Heather; Gamble, Carrol; Denegri, Simon; Muir, Delia; Simon, Natalie A; Thomas, Stephen; Elliot, Jim T; Bulbeck, Helen; Crocker, Joanna C; Planner, Claire; Vale, Claire; Clarke, Mike; Sprosen, Tim; Woolfall, Kerry

    2017-12-01

    Despite increasing international interest, there is a lack of evidence about the most efficient, effective and acceptable ways to implement patient and public involvement (PPI) in clinical trials. To identify the priorities of UK PPI stakeholders for methodological research to help resolve uncertainties about PPI in clinical trials. A modified Delphi process including a two round online survey and a stakeholder consensus meeting. In total, 237 people registered of whom 219 (92%) completed the first round. One hundred and eighty-seven of 219 (85%) completed the second; 25 stakeholders attended the consensus meeting. Round 1 of the survey comprised 36 topics; 42 topics were considered in round 2 and at the consensus meeting. Approximately 96% of meeting participants rated the top three topics as equally important. These were as follows: developing strong and productive working relationships between researchers and PPI contributors; exploring PPI practices in selecting trial outcomes of importance to patients; and a systematic review of PPI activity to improve the accessibility and usefulness of trial information (eg participant information sheets) for participants. The prioritized methodological research topics indicate important areas of uncertainty about PPI in trials. Addressing these uncertainties will be critical to enhancing PPI. Our findings should be used in the planning and funding of PPI in clinical trials to help focus research efforts and minimize waste. © 2017 The Authors Health Expectations Published by John Wiley & Sons Ltd.

  9. Training Needs of Clinical and Research Professionals to Optimize Minority Recruitment and Retention in Cancer Clinical Trials.

    Science.gov (United States)

    Niranjan, Soumya J; Durant, Raegan W; Wenzel, Jennifer A; Cook, Elise D; Fouad, Mona N; Vickers, Selwyn M; Konety, Badrinath R; Rutland, Sarah B; Simoni, Zachary R; Martin, Michelle Y

    2017-08-03

    The study of disparities in minority recruitment to cancer clinical trials has focused primarily on inquiries among minority patient populations. However, clinical trial recruitment is complex and requires a broader appreciation of the multiple factors that influence minority participation. One area that has received little attention is minority recruitment training for professionals who assume various roles in the clinical trial recruitment process. Therefore, we assessed the perspectives of cancer center clinical and research personnel on their training and education needs toward minority recruitment for cancer clinical trials. Ninety-one qualitative interviews were conducted at five U.S. cancer centers among four stakeholder groups: cancer center leaders, principal investigators, referring clinicians, and research staff. Interviews were recorded and transcribed. Qualitative analyses focused on response data related to training for minority recruitment for cancer clinical trials. Four prominent themes were identified: (1) Research personnel are not currently being trained to focus on recruitment and retention of minority populations; (2) Training for minority recruitment and retention provides for a specific focus on factors influencing minority research participation; (3) Training on cultural awareness may help to bridge cultural gaps between potential minority participants and research professionals; (4) Views differ regarding the importance of research personnel training designed to focus on recruitment of minority populations. There is a lack of systematic training for minority recruitment. Many stakeholders acknowledged the benefits of minority recruitment training and welcomed training that focuses on increasing cultural awareness to increase the participation of minorities in cancer clinical trials.

  10. Employing open/hidden administration in psychotherapy research: A randomized-controlled trial of expressive writing

    Science.gov (United States)

    Tondorf, Theresa; Kaufmann, Lisa-Katrin; Degel, Alexander; Locher, Cosima; Birkhäuer, Johanna; Gerger, Heike; Ehlert, Ulrike

    2017-01-01

    Psychotherapy has been shown to be effective, but efforts to prove specific effects by placebo-controlled trials have been practically and conceptually hampered. We propose that adopting open/hidden designs from placebo research would offer a possible way to establish specificity in psychotherapy. Therefore, we tested the effects of providing opposing treatment rationales in an online expressive writing intervention on affect in healthy subjects. Results indicate that it was possible to conduct the expressive writing intervention both covertly and openly, but that participants in the hidden administration condition did not fully benefit from the otherwise effective expressive writing intervention in the long-run. Effect sizes between open and hidden administration groups were comparable to pre-post effect sizes of the intervention. While this finding is important for the understanding of psychotherapy's effects per se, it also proves that alternative research approaches to establish specificity are feasible and informative in psychotherapy research. Trial registration: German Clinical Trials Register DRKS00009428 PMID:29176768

  11. 75 FR 8673 - Mid-Atlantic Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-02-25

    ... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... Mid-Atlantic Fishery Management Council (Council) will conduct an educational workshop on catch shares in cooperation with the Fisheries Leadership and Sustainability Forum (FLSF), the Atlantic States...

  12. Coordinating Council. Ninth Meeting: Total Quality Management

    Science.gov (United States)

    1992-01-01

    This report summarizes the 9th meeting of the STI Coordinating Council. The council listened to the speakers' understanding of Total Quality Management (TQM) principles and heard stories of successful applications of these principles. Definitions of quality stated were focused on customer satisfaction. Reports presented by the speakers are also included.

  13. 75 FR 4588 - NASA Advisory Council; Meeting

    Science.gov (United States)

    2010-01-28

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 10-011] NASA Advisory Council; Meeting... Committee of the NASA Advisory Council. This will be the first meeting of this Committee. DATES: February 11, 2010--11 a.m.-1 p.m. (EST). Meet-Me-Number: 1-877-613-3958; 2939943. ADDRESSES: NASA Headquarters, 300...

  14. 77 FR 9997 - NASA Advisory Council; Meeting

    Science.gov (United States)

    2012-02-21

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (12-016)] NASA Advisory Council; Meeting... Space Administration announces a meeting of the NASA Advisory Council (NAC). DATES: Thursday, March 8, 2012, 8 a.m.-5 p.m., local time and Friday, March 9, 2012, 8 a.m.-12 p.m., local time. ADDRESSES: NASA...

  15. 78 FR 7757 - Council Coordination Committee Meeting

    Science.gov (United States)

    2013-02-04

    ... issues of relevance to the Councils, including FY 2013 budget allocations and budget planning for FY 2014... will be held at the Sheraton Silver Spring Hotel, 8777 Georgia Avenue, Silver Spring, MD 20001... reports (continued) 11:15-12:15--Management and Budget Update FY2012: Status, Council funding FY2013...

  16. 75 FR 81232 - Council Coordination Committee Meeting

    Science.gov (United States)

    2010-12-27

    ... issues of relevance to the Councils, including FY 2011 budget allocations and budget planning, Annual... be held at the Phoenix Park Hotel, 520 North Capitol Street, NW., Washington, DC 20001, telephone 1...:30-2:15 Performance Measures. 2:15-3:15 Budget Issues FY11: Status, Allocation, Council Grants. FY12...

  17. 75 FR 20567 - Mid-Atlantic Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-04-20

    ... Mid-Atlantic Fishery Management Council's (MAFMC) Scientific and Statistical Committee (SSC) will hold... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... Fishery Management Council, 800 N. State Street, Suite 201, Dover, DE 19901; telephone: (302) 674-2331...

  18. 75 FR 55743 - Mid-Atlantic Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-09-14

    ... Mid-Atlantic Fishery Management Council's (MAFMC) Scientific and Statistical Committee (SSC) will hold... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... address: Mid-Atlantic Fishery Management Council, 800 N. State Street, Suite 201, Dover, DE 19901...

  19. Prostate Cancer Research Trial Helps John Spencer Treat His Cancer | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... of this page please turn Javascript on. Feature: Prostate Cancer Prostate Cancer Research Trial Helps John Spencer Treat His Cancer ... because of timely detection and treatment of his prostate cancer. He participated in an NIH-sponsored clinical trial. ...

  20. 2017 Elections to Staff Council

    CERN Multimedia

    Staff Association

    2017-01-01

    Make your voice heard, support your candidates! After verification by the Electoral Commission, all candidates for the elections to the Staff Council have been registered. It is now up to you, members of the Staff Association, to vote for the candidate(s) of your choice. We hope that you will be many to vote and to elect the new Staff Council! By doing so, you can support and encourage the women and men, who will represent you over the next two years. We are using an electronic voting system; all you need to do is click the link below and follow the instructions on the screen. https://ap-vote.web.cern.ch/elections-2017 The deadline for voting is Monday, 13 November at midday (12 pm). Elections Timetable Monday 13 November, at noon Closing date for voting Tuesday 21 November and Tuesday 5 December Publication of the results in Echo Monday 27 and Tuesday 28 November Staff Association Assizes Tuesday 5 December (afternoon) First meeting of the new Staff Council and election of the new Executive Committee The ...

  1. Design of the Intravenous Magnesium Efficacy in Acute Stroke (IMAGES trial [ISRCTN19943732

    Directory of Open Access Journals (Sweden)

    Lees Kennedy

    2000-12-01

    Full Text Available Abstract The Intravenous Magnesium Efficacy in Acute Stroke (IMAGES trial is a multicentre,randomised, placebo-controlled trial of magnesium sulphate (MgSO4 funded by the UK Medical Research Council. When complete, it will be the largest single neuroprotective study undertaken to date. Conscious patients presenting within 12 h of acute stroke with limb weakness are eligible. The primary outcome measure is combined death and disability as measured using the Barthel Index at 90-day follow up. By randomizing 2700 patients, the study will have 84% power to detect a 5.5% absolute reduction in the primary end-point. By April 2000, 86 centres were participating, with representation in Canada, USA, Europe, South America, Singapore and Australia. So far, 1206 patients have been randomised, of whom 37% were treated within 6 h. Overall 3-month mortality was 20% and the primary outcome event rate was 43%. The study is ongoing and centres worldwide are encouraged to participate.

  2. Medicare Appeals Council Decisions

    Data.gov (United States)

    U.S. Department of Health & Human Services — Decisions of the Departmental Appeals Board's Medicare Appeals Council involving claims for entitlement to Medicare and individual claims for Medicare coverage and...

  3. 76 FR 3878 - Mid-Atlantic Fishery Management Council; Public Meeting

    Science.gov (United States)

    2011-01-21

    ... Mid-Atlantic Fishery Management Council's (MAFMC) Scientific and Statistical Committee (SSC) will hold... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National.... ADDRESSES: The webinar will be held at Mid-Atlantic Fishery Management Council, 800 N. State Street, Suite...

  4. 75 FR 56994 - Mid-Atlantic Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-09-17

    ... Mid-Atlantic Fishery Management Council's (MAFMC) Scientific and Statistical Committee (SSC) will hold... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National.... ADDRESSES: The webinar will be held at Mid-Atlantic Fishery Management Council, 800 N. State Street, Suite...

  5. 77 FR 6786 - Western Pacific Fishery Management Council; Public Meetings

    Science.gov (United States)

    2012-02-09

    ... Pacific Fishery Management Council; Public Meetings AGENCY: National Marine Fisheries Service (NMFS... meeting dates and times. SUMMARY: The Western Pacific Fishery Management Council (Council) announces... Merizo Community Meeting 6 p.m.-9 p.m., Wednesday, February 29, 2012 1. Introduction 2. Community Based...

  6. 77 FR 75695 - Overseas Schools Advisory Council; Notice of Meeting

    Science.gov (United States)

    2012-12-21

    ... DEPARTMENT OF STATE [Public Notice 8130] Overseas Schools Advisory Council; Notice of Meeting The Overseas Schools Advisory Council, Department of State, will hold its Executive Committee Meeting on.... The Overseas Schools Advisory Council works closely with the U.S. business community in improving...

  7. 76 FR 78079 - Overseas Schools Advisory Council Notice of Meeting

    Science.gov (United States)

    2011-12-15

    ... DEPARTMENT OF STATE [Public Notice 7712] Overseas Schools Advisory Council Notice of Meeting The Overseas Schools Advisory Council, Department of State, will hold its Executive Committee Meeting on.... The Overseas Schools Advisory Council works closely with the U.S. business community in improving...

  8. 78 FR 77195 - Overseas Schools Advisory Council; Notice of Meeting

    Science.gov (United States)

    2013-12-20

    ... DEPARTMENT OF STATE [Public Notice 8564] Overseas Schools Advisory Council; Notice of Meeting The Overseas Schools Advisory Council, Department of State, will hold its Executive Committee Meeting on.... The Overseas Schools Advisory Council works closely with the U.S. business community in improving...

  9. The Status of Vocational Teacher Education in University Council for Vocational Education Member Institutions. Research Report.

    Science.gov (United States)

    Anderson, B. Harold

    The purpose of the study reported in this document was to describe the quantitative and qualitative characteristics of the vocational teacher education programs among institutions that are members of the University Council for Vocational Education. A questionnaire was mailed to representatives of each member institution in October 1985, with a 100…

  10. UN human rights council

    Directory of Open Access Journals (Sweden)

    Vuksanović Mlrjana

    2014-01-01

    Full Text Available The paper deals with the structure, mechanisms, practices and perspectives of the Human Rights Council, the UN body that, at universal level is the most important body in this area. Introductory section provides for a brief overview of the origins of human rights and the work of the Commission on Human Rights, in whose jurisdiction were questions of human rights before the establishment of the Council. After the introductory section the author gives an analysis of the structure, objectives, mandate and main procedures for the protection of human rights within the united Nations. In the final section the authorpoints out the advantages of this authority and criticism addressed to it, with emphasis on the possibility and the need for its reform.

  11. Research ethics board approval for an international thromboprophylaxis trial.

    Science.gov (United States)

    Lutz, Kristina; Wilton, Kelly; Zytaruk, Nicole; Julien, Lisa; Hall, Richard; Harvey, Johanne; Skrobik, Yoanna; Vlahakis, Nicholas; Meade, Laurie; Matte, Andrea; Meade, Maureen; Burns, Karen; Albert, Martin; Cash, Bronwyn Barlow; Vallance, Shirley; Klinger, James; Heels-Ansdell, Diane; Cook, Deborah

    2012-06-01

    Research ethics board (REB) review of scientific protocols is essential, ensuring participants' dignity, safety, and rights. The objectives of this study were to examine the time from submission to approval, to analyze predictors of approval time, and to describe the scope of conditions from REBs evaluating an international thromboprophylaxis trial. We generated survey items through literature review and investigators' discussions, creating 4 domains: respondent and institutional demographics, the REB application process, and alternate consent models. We conducted a document analysis that involved duplicate assessment of themes from REB critique of the protocol and informed consent forms (ICF). Approval was granted from 65 REB institutions, requiring 58 unique applications. We analyzed 44 (75.9%) of 58 documents and surveys. Survey respondents completing the applications had 8 (5-12) years of experience; 77% completed 4 or more REB applications in previous 5 years. Critical care personnel were represented on 54% of REBs. The time to approval was a median (interquartile range) of 75 (42, 150) days, taking longer for sites with national research consortium membership (89.1 vs 31.0 days, P = .03). Document analysis of the application process and ICF yielded 5 themes: methodology, data management, consent procedures, cataloguing, and miscellaneous. Protocol-specific themes focused on trial implementation, external critiques, and budget. The only theme specific to the ICF was risks and benefits. The most frequent comments on the protocol and ICF were about methodology and miscellaneous issues; ICF comments also addressed study risks and benefits. More studies on methods to enhance efficiency and consistency of the REB approval processes for clinical trials are needed while still maintaining high ethical standards. Copyright © 2012 Elsevier Inc. All rights reserved.

  12. Antiplatelet therapy and the effects of B vitamins in patients with previous stroke or transient ischaemic attack: a post-hoc subanalysis of VITATOPS, a randomised, placebo-controlled trial.

    Science.gov (United States)

    Hankey, Graeme J; Eikelboom, John W; Yi, Qilong; Lees, Kennedy R; Chen, Christopher; Xavier, Denis; Navarro, Jose C; Ranawaka, Udaya K; Uddin, Wasim; Ricci, Stefano; Gommans, John; Schmidt, Reinhold

    2012-06-01

    revascularisation procedure. Of the participants taking antiplatelet drugs at baseline, B vitamins had no significant effect on the primary outcome (488 patients in the B-vitamins group [15%] vs 519 in the placebo group [16%]; hazard ratio [HR] 0·94, 95% CI 0·83-1·07). By contrast, of the participants not taking antiplatelet drugs at baseline, B vitamins had a significant effect on the primary outcome (123 in the B-vitamins group [17%] vs 153 in the placebo group [21%]; HR 0·76, 0·60-0·96). The interaction between antiplatelet therapy and the effect of B vitamins on the primary outcome was significant after adjusting for imbalance in the baseline variables (adjusted p for interaction=0·0204). Our findings support the hypothesis that antiplatelet therapy modifies the potential benefits of lowering homocysteine with B-vitamin supplementation in the secondary prevention of major vascular events. If validated, B vitamins might have a role in the prevention of ischaemic events in high-risk individuals with an allergy, intolerance, or lack of indication for antiplatelet therapy. Australia National Health and Medical Research Council, UK Medical Research Council, Singapore Biomedical Research Council, and Singapore National Medical Research Council. Copyright © 2012 Elsevier Ltd. All rights reserved.

  13. The Council of Academic Hospitals of Ontario (CAHO) Adopting Research to Improve Care (ARTIC) Program: Reach, Sustainability, Spread and Lessons Learned from an Implementation Funding Model.

    Science.gov (United States)

    Moore, Julia E; Grouchy, Michelle; Graham, Ian D; Shandling, Maureen; Doyle, Winnie; Straus, Sharon E

    2016-05-01

    Despite evidence on what works in healthcare, there is a significant gap in the time it takes to bring research into practice. The Council of Academic Hospitals of Ontario's Adopting Research to Improve Care program addresses this research-to-practice gap by incorporating the following components into its funding program: strategic selection of evidence for implementation, education and training for implementation, implementation supports, executive champions and governance, and evaluation. Funded projects have been sustained (76% reported full sustainability) and spread to over 200 new sites. Lessons learned include the following: assess readiness, develop tailored implementation materials, consider characteristics of implementation supports, protect champion time and consider evaluation feasibility. Copyright © 2016 Longwoods Publishing.

  14. 78 FR 46590 - Office of the Assistant Secretary for Planning and Evaluation; Advisory Council on Alzheimer's...

    Science.gov (United States)

    2013-08-01

    ... Evaluation; Advisory Council on Alzheimer's Research, Care, and Services AGENCY: Office of the Assistant... Alzheimer's Research, Care, and Services. The six positions are for each of the following categories, as specified in the National Alzheimer's Project Act: Alzheimer's patient advocate, Alzheimer's caregiver...

  15. 78 FR 33421 - Office of the Assistant Secretary for Planning and Evaluation; Advisory Council on Alzheimer's...

    Science.gov (United States)

    2013-06-04

    ... Evaluation; Advisory Council on Alzheimer's Research, Care, and Services AGENCY: Office of the Assistant... Alzheimer's Research, Care, and Services. Specifically, the position is for someone with a diagnosis of Alzheimer's disease or a related dementia. Nominations should include the nominee's contact information...

  16. 77 FR 50472 - New England Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-08-21

    ... Region Logbook Family of Forms Federal Register (77 FR 153, 8/8/12). Other business may be discussed. The... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... England Fishery Management Council's (Council) VMS/ Enforcement Committee and Advisory Panel will meet to...

  17. 77 FR 33229 - Sport Fishing and Boating Partnership Council Charter

    Science.gov (United States)

    2012-06-05

    ... DEPARTMENT OF THE INTERIOR Office of the Secretary Sport Fishing and Boating Partnership Council... Secretary of the Interior has renewed the Sport Fishing and Boating Partnership Council (Council) charter... and support for the Sport Fish Restoration and Boating Trust Fund. d. Recommending policies or...

  18. 75 FR 177 - Overseas Schools Advisory Council Notice of Meeting

    Science.gov (United States)

    2010-01-04

    ... DEPARTMENT OF STATE [Public Notice Number 6844] Overseas Schools Advisory Council Notice of Meeting The Overseas Schools Advisory Council, Department of State, will hold its Executive Committee... 12 p.m. The Overseas Schools Advisory Council works closely with the U.S. business community in...

  19. 77 FR 32168 - Overseas Schools Advisory Council Notice of Meeting

    Science.gov (United States)

    2012-05-31

    ... DEPARTMENT OF STATE [Public Notice 7904] Overseas Schools Advisory Council Notice of Meeting The Overseas Schools Advisory Council, Department of State, will hold its Annual Meeting on Thursday, June 21... Schools Advisory Council works closely with the U.S. business community in improving those American...

  20. 78 FR 33465 - Overseas Schools Advisory Council; Notice of Meeting

    Science.gov (United States)

    2013-06-04

    ... DEPARTMENT OF STATE [Public Notice 8346] Overseas Schools Advisory Council; Notice of Meeting The Overseas Schools Advisory Council, Department of State, will hold its Annual Meeting on Thursday, June 27... Schools Advisory Council works closely with the U.S. business community in improving those American...

  1. 75 FR 80566 - Overseas Schools Advisory Council Notice of Meeting

    Science.gov (United States)

    2010-12-22

    ... DEPARTMENT OF STATE [Public Notice Number 7171] Overseas Schools Advisory Council Notice of Meeting The Overseas Schools Advisory Council, Department of State, will hold its Executive Committee... 12 p.m. The Overseas Schools Advisory Council works closely with the U.S. business community in...

  2. 77 FR 22286 - Western Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-04-13

    ... Pacific Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS.... SUMMARY: The Western Pacific Fishery Management Council (Council) will hold a meeting of its Pelagics Plan... pelagics annual report module changes 4. American Samoa annual report module changes 5. Summary of current...

  3. Reducing placebo exposure in trials: Considerations from the Research Roundtable in Epilepsy.

    Science.gov (United States)

    Fureman, Brandy E; Friedman, Daniel; Baulac, Michel; Glauser, Tracy; Moreno, Jonathan; Dixon-Salazar, Tracy; Bagiella, Emilia; Connor, Jason; Ferry, Jim; Farrell, Kathleen; Fountain, Nathan B; French, Jacqueline A

    2017-10-03

    The randomized controlled trial is the unequivocal gold standard for demonstrating clinical efficacy and safety of investigational therapies. Recently there have been concerns raised about prolonged exposure to placebo and ineffective therapy during the course of an add-on regulatory trial for new antiepileptic drug approval (typically ∼6 months in duration), due to the potential risks of continued uncontrolled epilepsy for that period. The first meeting of the Research Roundtable in Epilepsy on May 19-20, 2016, focused on "Reducing placebo exposure in epilepsy clinical trials," with a goal of considering new designs for epilepsy regulatory trials that may be added to the overall development plan to make it, as a whole, safer for participants while still providing rigorous evidence of effect. This topic was motivated in part by data from a meta-analysis showing a 3- to 5-fold increased rate of sudden unexpected death in epilepsy in participants randomized to placebo or ineffective doses of new antiepileptic drugs. The meeting agenda included rationale and discussion of different trial designs, including active-control add-on trials, placebo add-on to background therapy with adjustment, time to event designs, adaptive designs, platform trials with pooled placebo control, a pharmacokinetic/pharmacodynamic approach to reducing placebo exposure, and shorter trials when drug tolerance has been ruled out. The merits and limitations of each design were discussed and are reviewed here. © 2017 American Academy of Neurology.

  4. Global health trials methodological research agenda:results from a priority setting exercise

    OpenAIRE

    Blazeby, Jane; Nasser, Mona; Soares-Weiser, Karla; Sydes, Matthew R.; Zhang, Junhua; Williamson, Paula R

    2018-01-01

    BackgroundMethodological research into the design, conduct, analysis and reporting of trials is essential to optimise the process. UK specialists in the field have established a set of top priorities in aid of this research. These priorities however may not be reflected in the needs of similar research in low to middle income countries (LMICs) with different healthcare provision, resources and research infrastructure. The aim of the study was to identify the top priorities for methodological ...

  5. Bioethical Perspectives for Ageing. The documents produced by the Ethics Councils

    Directory of Open Access Journals (Sweden)

    Lucília Nunes

    2015-08-01

    Full Text Available Aging attracted keen interest in research, health, education as well as cross-sectors approaches. We researched what has been produced by the National Bioethics/Ethics Councils in the form of opinions or other documents, relating to aging and elderly people. In the websi-tes of the 28 EU councils and 12 other countries, we identified 4 documents relating to aging and 8 opinions, which we analyse. The Councils have proposed to draw the attention and reflection of public opinion to the elderly condition; all agree that the age has its own traits and that matters revert to a “culture of old age”, respect and promotion of a positive aging. Enhance the diversity of modes of aging and the importance of preparing all, promoting literacy for aging, creating social and legal protective elements (Elderly Statute, Observatory of the Elderly Conditions. From the analysis, a set of principles and bioethical elements: [1] respect for human dignity, regardless of the stage of life; [2] recognition of the person’s situation uniqueness to aging; [3] freedom of one’s own decision, which is materialized in respect for autonomy; [4] recognition of the vulnerabilities of the elderly, [5] ethical commitment and social responsibility in monitoring the elderly, [6] non-discrimination by age and [7] the guidance to the conditions of the integral good and quality of life. Aging is an existential step for which we can prepare, on the assumption that human life in its longevity, interweaves those who are older and those younger, on the crucial issue of human existence.

  6. Patients' health or company profits? The commercialisation of academic research.

    Science.gov (United States)

    Olivieri, Nancy F

    2003-01-01

    This paper is a personal account of the events associated with the author's work at the University of Toronto's Hospital for Sick Children on a drug, deferiprone, for the treatment of thalassaemia. Trials of the drug were sponsored by the Canadian Medical Research Council and a drug company which would have been able, had the trials been successful, to seek regulatory approval to market the drug. When evidence emerged that deferiprone might be inadequately effective in a substantial proportion of patients, the drug company issued legal threats when the author proposed informing her patients and the scientific community. Until protests were made by international authorities in her field of research, the hospital and university did not adequately support the author's academic freedom and responsibilities as a medical practitioner. It is argued that underlying cause of this, and of other similar cases, is the political philosophy which is driving the commercialisation of universities and bringing about the deregulation of drug approval procedures. Together these changes constitute a serious threat to the public good.

  7. Transparency in the Council of the European Union

    DEFF Research Database (Denmark)

    Laursen, Bo

    2013-01-01

    with information and thereby act as day-to-day facilitators of transparency of the Council’s activities. Although these communicators see themselves as contributing substantially to the transparency of the Council’s work and thereby as enabling the media to provide EU citizens with information about one......The Council of the European Union is often described as the least transparent of the three big EU institutions although steps have been taken to improve the transparency of its activities during the last couple of decades. This article focuses on the Council’s press officers who provide journalists...... of the most powerful political forums in Europe, transparency in the Council has its limits. This study explores institutional factors which hinder Council press officers from being as transparent as journalists would like them to be. In-depth, semi-structured interviews with Council press officers...

  8. 75 FR 5803 - John Day/Snake Resource Advisory Council; Meetings

    Science.gov (United States)

    2010-02-04

    ...] John Day/Snake Resource Advisory Council; Meetings AGENCY: Bureau of Land Management, Interior. ACTION: Meeting Notice for the John Day/Snake Resource Advisory Council. SUMMARY: Pursuant to the Federal Land..., Bureau of Land Management (BLM) John Day/Snake Resource Advisory Council (JDSRAC) will meet as indicated...

  9. 77 FR 11514 - National Advisory Council on Indian Education (NACIE)

    Science.gov (United States)

    2012-02-27

    ... DEPARTMENT OF EDUCATION National Advisory Council on Indian Education (NACIE) AGENCY: U.S... Council on Indian Education (the Council) and is intended to notify the general public of the meeting... established within the Department of Education to advise the Secretary of Education on the funding and...

  10. 78 FR 32639 - National Advisory Council on Indian Education (NACIE)

    Science.gov (United States)

    2013-05-31

    ... DEPARTMENT OF EDUCATION National Advisory Council on Indian Education (NACIE) AGENCY: U.S... Council on Indian Education (the Council) and is intended to notify the general public of the meeting... established within the Department of Education to advise the Secretary of Education on the funding and...

  11. 76 FR 62042 - Gulf of Mexico Fishery Management Council (Council); Public Meetings

    Science.gov (United States)

    2011-10-06

    ... INFORMATION CONTACT: Dr. Stephen Bortone, Executive Director, Gulf of Mexico Fishery Management Council..., Sustainable Fisheries/Ecosystem, Red Drum, Advisory Panel Selection, Scientific & Statistical Committee... to discuss the Summary of the October 2011 Scientific & Statistical Committee Meeting, review the...

  12. 75 FR 1058 - President's Advisory Council for Faith-based and Neighborhood Partnerships

    Science.gov (United States)

    2010-01-08

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES President's Advisory Council for Faith-based and...-463), the President's Advisory Council for Faith-based and Neighborhood Partnerships announces the following meeting: Name: President's Advisory Council for Faith-based and Neighborhood Partnerships Council...

  13. 75 FR 5331 - President's Advisory Council for Faith-Based and Neighborhood Partnerships

    Science.gov (United States)

    2010-02-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES President's Advisory Council for Faith-Based and...-463), the President's Advisory Council for Faith-Based and Neighborhood Partnerships announces the following meeting: Name: President's Advisory Council for Faith-Based and Neighborhood Partnerships Council...

  14. 75 FR 4822 - President's Advisory Council for Faith-Based and Neighborhood Partnerships

    Science.gov (United States)

    2010-01-29

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES President's Advisory Council for Faith-Based and...-463), the President's Advisory Council for Faith-based and Neighborhood Partnerships announces the following meeting: Name: President's Advisory Council for Faith-based and Neighborhood Partnerships Council...

  15. 75 FR 8079 - President's Advisory Council on Faith-Based and Neighborhood Partnerships

    Science.gov (United States)

    2010-02-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES President's Advisory Council on Faith-Based and...-463), the President's Advisory Council on Faith-Based and Neighborhood Partnerships announces the following meetings: Name: President's Advisory Council on Faith-based and Neighborhood Partnerships Council...

  16. The N-of-1 Clinical Trial: A Timely Research Opportunity in Homeopathy.

    Science.gov (United States)

    Ulbrich-Zürni, Susanne; Teut, Michael; Roll, Stephanie; Mathie, Robert T

    2018-02-01

     The randomised controlled trial (RCT) is considered the 'gold standard' for establishing treatment efficacy or effectiveness of an intervention, but its data do not infer response in an individual patient. Individualised clinical care, a fundamental principle in complementary and alternative medicine (CAM), including homeopathy, seems well disposed in principle to being researched by single-patient (N-of-1) study design. Guidelines for reporting N-of-1 trials have recently been developed.  To overview the current status in the literature of the N-of-1 method and its application in medicine, including CAM. To consider whether the N-of-1 trial design offers an opportunity for novel research in homeopathy. N-OF-1 TRIAL DESIGN:  The N-of-1 trial applies the principles of the conventional crossover, blinded, RCT design. The treatment under study and the comparator are repeated in a randomised order, and with suitable washout time, over a defined period. N-of-1 design is constrained for use in chronic stable conditions, and for interventions that have quick onset and cessation of effect, with modest or negligible carryover. Outcome data can be aggregated and interpreted for the individual subject; they can also be pooled with data from several similar N-of-1 trials, enabling more generalisable conclusions. THE N-OF-1 TRIAL IN CAM: The typical individualisation of patient care can be accommodated in N-of-1 study design if the patient and the specific therapeutic intervention are selected within the constraints of the method. Application of the N-of-1 method in CAM has been advocated but has been mainly limited, in practice, to a small number of studies in herbal and traditional Chinese medicine. THE N-OF-1 TRIAL IN HOMEOPATHY:  Individualised homeopathy can be accommodated for investigation within the same methodological constraints; less in-depth homeopathic approaches to prescribing are also amendable to investigation using the N-of-1 method. No such studies

  17. School and district wellness councils and availability of low-nutrient, energy-dense vending fare in Minnesota middle and high schools.

    Science.gov (United States)

    Kubik, Martha Y; Lytle, Leslie A; Farbakhsh, Kian

    2011-01-01

    The Child Nutrition and WIC Reauthorization Act of 2004 required school districts participating in the federal school meals program to establish by the start of the 2006-2007 school year policies that included nutrition guidelines for all foods sold on school campus during the school day and policy development involving key stakeholders. For many schools, policy development was done by wellness councils. This study examined the association between having a wellness council and availability of low-nutrient, energy-dense foods/beverages in school vending machines following enactment of the federal legislation. In 2006-2007, Minnesota middle (n=35) and high (n=54) school principals reported whether their school and district had a wellness council. Trained research staff observed foods/beverages in vending machines accessible to students. Low-nutrient, energy-dense foods/beverages (snacks >3 g fat or >200 calories/serving, and soda, fruit/sport drinks and reduced-fat/whole milk) were grouped into seven categories (eg, high-fat baked goods) and a food score was calculated. Higher scores indicated more low-nutrient, energy-dense vending fare. Multivariate linear regression, adjusted for school characteristics, was used to examine associations between scores and a three-category council variable (district-only; district and school; no council). Among schools, 53% had district-only councils, 38% district and school councils, and 9% had no council. Schools with both a district and school council had a significantly lower mean food score than schools without councils (P=0.03). The potential of wellness councils to impact availability of low-nutrient, energy-dense vending fare is promising. There may be an added benefit to having both a school and district council. Copyright © 2011 American Dietetic Association. Published by Elsevier Inc. All rights reserved.

  18. Qualitative Research in Palliative Care: Applications to Clinical Trials Work.

    Science.gov (United States)

    Lim, Christopher T; Tadmor, Avia; Fujisawa, Daisuke; MacDonald, James J; Gallagher, Emily R; Eusebio, Justin; Jackson, Vicki A; Temel, Jennifer S; Greer, Joseph A; Hagan, Teresa; Park, Elyse R

    2017-08-01

    While vast opportunities for using qualitative methods exist within palliative care research, few studies provide practical advice for researchers and clinicians as a roadmap to identify and utilize such opportunities. To provide palliative care clinicians and researchers descriptions of qualitative methodology applied to innovative research questions relative to palliative care research and define basic concepts in qualitative research. Body: We describe three qualitative projects as exemplars to describe major concepts in qualitative analysis of early palliative care: (1) a descriptive analysis of clinician documentation in the electronic health record, (2) a thematic content analysis of palliative care clinician focus groups, and (3) a framework analysis of audio-recorded encounters between patients and clinicians as part of a clinical trial. This study provides a foundation for undertaking qualitative research within palliative care and serves as a framework for use by other palliative care researchers interested in qualitative methodologies.

  19. 76 FR 13604 - Western Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2011-03-14

    .... SUMMARY: The Western Pacific Fishery Management Council (Council) will hold a Western Pacific Stock... councils and NOAA Fisheries to conduct a review and revision of the EFH components of fisheries management... and enhancement of EFH for each Fishery Management Plan. The Act requires that both steps of the...

  20. 75 FR 43928 - New England Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-07-27

    ... effects of fishing on Essential Fish Habitat (EFH) across all Council FMPs. These management options are being developed as part of Phase 2 of Essential Fish Habitat Omnibus Amendment 2. Broadly speaking, the... England Fishery Management Council (Council) is scheduling a public meeting of its Habitat/MPA/Ecosystem...

  1. Personality and culture, the Social Science Research Council, and liberal social engineering: the Advisory Committee on Personality and Culture, 1930-1934.

    Science.gov (United States)

    Bryson, Dennis

    2009-01-01

    The field of personality and culture was given a significant impetus during the 1930s with the establishment of the Advisory Committee on Personality and Culture (1930-1934) by the Social Science Research Council. This committee provided an early formulation of personality and culture that emphasized the interdisciplinary focus on the processes of personality formation within small-scale social settings. The committee's formulation also coupled personality and culture with a liberal social engineering approach geared toward cultural reconstruction. Major social scientists and clinicians were involved in the activities of the committee, including Edward Sapir, W. I. Thomas, E. W. Burgess, E. A. Bott, Robert S. Woodworth, Harry Stack Sullivan, C. M. Hincks, and Adolf Meyer.

  2. Process evaluation of complex interventions: Medical Research Council guidance

    OpenAIRE

    Moore, G.F.; Audrey, S.; Barker, M.; Bond, L.; Bonell, C.; Hardeman, W.; Moore, L.; O'Cathain, A.; Tinati, T.; Wight, D.; Baird, J.

    2015-01-01

    Attempts to tackle problems such as smoking and obesity increasingly use complex interventions. These are commonly defined as interventions that comprise multiple interacting components, although additional dimensions of complexity include the difficulty of their implementation and the number of organisational levels they target.1 Randomised controlled trials are regarded as the gold standard for establishing the effectiveness of interventions, when randomisation is feasible. However, effect ...

  3. Medical research in emergency research in the European Union member states: tensions between theory and practice.

    Science.gov (United States)

    Kompanje, Erwin J O; Maas, Andrew I R; Menon, David K; Kesecioglu, Jozef

    2014-04-01

    In almost all of the European Union member states, prior consent by a legal representative is used as a substitute for informed patient consent for non-urgent medical research. Deferred (patient and/or proxy) consent is accepted as a substitute in acute emergency research in approximately half of the member states. In 12 European Union member states emergency research is not mentioned in national law. Medical research in the European Union is covered by the Clinical Trial Directive 2001/20/EC. A proposal for a regulation by the European Commission is currently being examined by the European Parliament and the Council and will replace Directive 2001/20/EC. Deferred patient and/or proxy consent is allowed in the proposed regulation, but does not fit completely in the practice of emergency research. For example, deferred consent is only possible when legal representatives are not available. This criterion will delay inclusion of patients in acute life-threatening conditions in short time frames. As the regulation shall be binding in its entirety in all member states, emergency research in acute situations is still not possible as it should be.

  4. 76 FR 6402 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2011-02-04

    ... Pacific Fishery Management Council's (Pacific Council) Groundfish Essential Fish Habitat Review Committee... review of Essential Fish Habitat (EFH) descriptions for Pacific Coast groundfish species. Major topics of...

  5. 75 FR 49508 - Navigation Safety Advisory Council; Vacancies

    Science.gov (United States)

    2010-08-13

    ... Council; Vacancies AGENCY: Coast Guard, DHS. ACTION: Request for applications. SUMMARY: The Coast Guard seeks applications for membership on the Navigation Safety Advisory Council (NAVSAC). This Committee... prevention of collisions, rammings, and groundings. This includes, but is not limited to: Inland and...

  6. 76 FR 33773 - Navigation Safety Advisory Council; Vacancies

    Science.gov (United States)

    2011-06-09

    ... Council; Vacancies AGENCY: Coast Guard, DHS. ACTION: Request for applications. SUMMARY: The Coast Guard seeks applications for membership on the Navigation Safety Advisory Council (NAVSAC). NAVSAC provides... the U.S. Coast Guard, on matters relating to prevention of maritime collisions, rammings, and...

  7. Randomised controlled trials of veterinary homeopathy: characterising the peer-reviewed research literature for systematic review.

    Science.gov (United States)

    Mathie, Robert T; Hacke, Daniela; Clausen, Jürgen

    2012-10-01

    Systematic review of the research evidence in veterinary homeopathy has never previously been carried out. This paper presents the search methods, together with categorised lists of retrieved records, that enable us to identify the literature that is acceptable for future systematic review of randomised controlled trials (RCTs) in veterinary homeopathy. All randomised and controlled trials of homeopathic intervention (prophylaxis and/or treatment of disease, in any species except man) were appraised according to pre-specified criteria. The following databases were systematically searched from their inception up to and including March 2011: AMED; Carstens-Stiftung Homeopathic Veterinary Clinical Research (HomVetCR) database; CINAHL; Cochrane Central Register of Controlled Trials; Embase; Hom-Inform; LILACS; PubMed; Science Citation Index; Scopus. One hundred and fifty records were retrieved; 38 satisfied the acceptance criteria (substantive report of a clinical treatment or prophylaxis trial in veterinary homeopathic medicine randomised and controlled and published in a peer-reviewed journal), and were thus eligible for future planned systematic review. Approximately half of the rejected records were theses. Seven species and 27 different species-specific medical conditions were represented in the 38 papers. Similar numbers of papers reported trials of treatment and prophylaxis (n=21 and n=17 respectively) and were controlled against placebo or other than placebo (n=18, n=20 respectively). Most research focused on non-individualised homeopathy (n=35 papers) compared with individualised homeopathy (n=3). The results provide a complete and clarified view of the RCT literature in veterinary homeopathy. We will systematically review the 38 substantive peer-reviewed journal articles under the main headings: treatment trials; prophylaxis trials. Copyright © 2012 The Faculty of Homeopathy. Published by Elsevier Ltd. All rights reserved.

  8. View all initiatives | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The Science Granting Councils Initiative in Sub-Saharan Africa is focused on strengthening the capacities of science granting councils in order to support research and evidence-based policies that will contribute to economic and social development in Sub-Saharan Africa. We fund researchers driving global change.

  9. 76 FR 28209 - Notice of Intent To Reestablish the National Genetic Resources Advisory Council, and Request for...

    Science.gov (United States)

    2011-05-16

    ... appointed members will be from the general public including leaders in, fields of public policy, trade... DEPARTMENT OF AGRICULTURE Agricultural Research Service Notice of Intent To Reestablish the National Genetic Resources Advisory Council, and Request for Nominations AGENCY: Agricultural Research...

  10. Council appoints CERN’s next Director General

    CERN Multimedia

    Maximilien Brice

    2007-01-01

    On 14 December 2007, CERN Council appointed Professor Rolf-Dieter Heuer to succeed Dr Robert Aymar as CERN Director General. Professor Heuer will serve a five-year term, taking office on 1 January 2009. From Left to right: Dr Robert Aymar, current CERN Director General, Professor Torsten Åkesson, President of CERN Council, and Professor Rolf-Dieter Heuer, CERN's next Director General.

  11. Clinical Trials

    Medline Plus

    Full Text Available ... or device is safe and effective for humans. What Are Clinical Trials? Clinical trials are research studies ... parents, clinicians, researchers, children, and the general public. What to Expect During a clinical trial, doctors, nurses, ...

  12. 76 FR 9553 - South Atlantic Fishery Management Council (Council); Public Meetings

    Science.gov (United States)

    2011-02-18

    ... Fishery Management Plan (FMP) addressing commercial trip limits and possible changes to black sea bass bag... Grouper FMP; black sea bass bag limit analysis; and the Comprehensive ACL Amendment. The Comprehensive ACL Amendment will specify ACLs, AMs and other values as mandated in the MSA for species managed by the Council...

  13. Research ethics committee decision-making in relation to an efficient neonatal trial.

    Science.gov (United States)

    Gale, C; Hyde, M J; Modi, N

    2017-07-01

    Randomised controlled trials, a gold-standard approach to reduce uncertainties in clinical practice, are growing in cost and are often slow to recruit. We determined whether methodological approaches to facilitate large, efficient clinical trials were acceptable to UK research ethics committees (RECs). We developed a protocol in collaboration with parents, for a comparative-effectiveness, randomised controlled trial comparing two widely used blood transfusion practices in preterm infants. We incorporated four approaches to improve recruitment and efficiency: (i) point-of-care design using electronic patient records for patient identification, randomisation and data acquisition, (ii) short two-page information sheet; (iii) explicit mention of possible inclusion benefit; (iv) opt-out consent with enrolment as the default. With the support of the UK Health Research Authority, we submitted an identical protocol to 12 UK REC. RECs in the UK. Number of REC granting favourable opinions. The use of electronic patient records was acceptable to all RECs; one REC raised concerns about the short parent information sheet, 10 about inclusion benefit and 9 about opt-out consent. Following responses to queries, nine RECs granted a favourable final opinion and three rejected the application because they considered the opt-out consent process invalid. A majority of RECs in this study consider the use of electronic patient record data, short information sheets, opt-out consent and mention of possible inclusion benefit to be acceptable in neonatal comparative-effectiveness research. We identified a need for guidance for RECs in relation to opt-out consent processes. These methods provide opportunity to facilitate large randomised controlled trials. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  14. Clinical Trials

    Medline Plus

    Full Text Available ... Clinical Trials About Clinical Trials Clinical trials are research studies that explore whether a medical strategy, treatment, ... required to have an IRB. Office for Human Research Protections The U.S. Department of Health and Human ...

  15. 76 FR 80890 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2011-12-27

    ... Airport Hotel, 7900 NE 82nd Avenue, Portland, OR 97220. Council address: Pacific Fishery Management.... Kerry Griffin, Staff Officer, Pacific Council; (503) 820-2280. SUPPLEMENTARY INFORMATION: The purpose of...

  16. 76 FR 43987 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2011-07-22

    ... Pacific Fishery Management Council's (Pacific Council) ad hoc groundfish Essential Fish Habitat Review... of groundfish Essential Fish Habitat (EFH). DATES: The work session will be held Thursday, October 6...

  17. 78 FR 49477 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-08-14

    ... Pacific Fishery Management Council (Pacific Council) will convene a meeting of its Groundfish Essential Fish Habitat Review Committee (EFHRC). DATES: The meeting will be held Wednesday September 4 through...

  18. Allegheny County Council Districts

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — This dataset portrays the boundaries of the County Council Districts in Allegheny County. The dataset is based on municipal boundaries and City of Pittsburgh ward...

  19. 76 FR 67482 - NASA Advisory Council; Charter Renewal

    Science.gov (United States)

    2011-11-01

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-108)] NASA Advisory Council; Charter Renewal AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of renewal and amendment of the charter of the NASA Advisory Council. SUMMARY: Pursuant to sections 14(b)(1) and 9(c) of...

  20. 78 FR 66964 - NASA Advisory Council; Charter Renewal

    Science.gov (United States)

    2013-11-07

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice: (13-130)] NASA Advisory Council; Charter Renewal AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of renewal and amendment of the charter of the NASA Advisory Council. SUMMARY: Pursuant to sections 14(b)(1) and 9(c) of...

  1. 75 FR 52375 - NASA Advisory Council; Exploration Committee

    Science.gov (United States)

    2010-08-25

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice: (10-094)] NASA Advisory Council... National Aeronautics and Space Administration announces a meeting of the Exploration Committee of the NASA Advisory Council. DATES: Tuesday, September 21, 2010, 1 p.m.-6:30 p.m., Local Time. ADDRESSES: NASA...

  2. President Ilves at the Atlantic Council / Ago Ambre

    Index Scriptorium Estoniae

    Ambre, Ago

    2010-01-01

    President Toomas Hendrik Ilvese esinemisest 19. märtsil 2010 Washingtonis transatlantilisi suhteid arendavas rahvusvahelises välis- ja julgeolekupoliitilises mõttekojas ja poliitikakeskuses Atlantic Council. Kohtumisest Atantic Council'i Ameerika Ühendriikide poolsete juhtidega. Töövisiit Ameerika Ühendriikidesse 17.-23.03.2010

  3. Who is the research subject in cluster randomized trials in health research?

    Directory of Open Access Journals (Sweden)

    Brehaut Jamie C

    2011-07-01

    Full Text Available Abstract This article is part of a series of papers examining ethical issues in cluster randomized trials (CRTs in health research. In the introductory paper in this series, we set out six areas of inquiry that must be addressed if the CRT is to be set on a firm ethical foundation. This paper addresses the first of the questions posed, namely, who is the research subject in a CRT in health research? The identification of human research subjects is logically prior to the application of protections as set out in research ethics and regulation. Aspects of CRT design, including the fact that in a single study the units of randomization, experimentation, and observation may differ, complicate the identification of human research subjects. But the proper identification of human research subjects is important if they are to be protected from harm and exploitation, and if research ethics committees are to review CRTs efficiently. We examine the research ethics literature and international regulations to identify the core features of human research subjects, and then unify these features under a single, comprehensive definition of human research subject. We define a human research subject as any person whose interests may be compromised as a result of interventions in a research study. Individuals are only human research subjects in CRTs if: (1 they are directly intervened upon by investigators; (2 they interact with investigators; (3 they are deliberately intervened upon via a manipulation of their environment that may compromise their interests; or (4 their identifiable private information is used to generate data. Individuals who are indirectly affected by CRT study interventions, including patients of healthcare providers participating in knowledge translation CRTs, are not human research subjects unless at least one of these conditions is met.

  4. Pediatric Clinical Trials Conducted in South Korea from 2006 to 2015: An Analysis of the South Korean Clinical Research Information Service, US ClinicalTrials.gov and European Clinical Trials Registries.

    Science.gov (United States)

    Choi, Sheung-Nyoung; Lee, Ji-Hyun; Song, In-Kyung; Kim, Eun-Hee; Kim, Jin-Tae; Kim, Hee-Soo

    2017-12-01

    The status of pediatric clinical trials performed in South Korea in the last decade, including clinical trials of drugs with unapproved indications for children, has not been previously examined. The aim was to provide information regarding the current state of pediatric clinical trials and create a basis for future trials performed in South Korea by reviewing three databases of clinical trials registrations. We searched for pediatric clinical studies (participants South Korea between 2006 and 2015 registered on the Clinical Research Information Service (CRIS), ClinicalTrials.gov, and the European Clinical Trials Registry (EuCTR). Additionally, we reviewed whether unapproved indications were involved in each trial by comparing the trials with a list of authorized trials provided by the Ministry of Food and Drug Safety (MFDS). The primary and secondary outcomes were to determine the change in number of pediatric clinical trials with unapproved indications over time and to assess the status of unauthorized pediatric clinical trials from the MFDS and the publication of articles after these clinical trials, respectively. We identified 342 clinical studies registered in the CRIS (n = 81), ClinicalTrials.gov (n = 225), and EuCTR (n = 36), of which 306 were reviewed after excluding duplicate registrations. Among them, 181 studies were interventional trials dealing with drugs and biological agents, of which 129 (71.3%) involved unapproved drugs. Of these 129 trials, 107 (82.9%) were authorized by the MFDS. Pediatric clinical trials in South Korea aiming to establish the safety and efficacy of drugs in children are increasing; however, non-MFDS-authorized studies remain an issue.

  5. 75 FR 14427 - Gulf of Mexico Fishery Management Council (Council); Public Meetings

    Science.gov (United States)

    2010-03-25

    .... Stephen Bortone, Executive Director, Gulf of Mexico Fishery Management Council; telephone: 813- 348-1630... Reef Fish Scientific and Statistical Committee; discuss Options Paper for Amendment 32 Gag/Red Grouper... Statistical Committee Acceptable Biological Catch Control Rule Report; discuss the Options Paper for the...

  6. Croatian energy regulatory council - independent Croatian regulatory body

    International Nuclear Information System (INIS)

    Klepo, M.

    2002-01-01

    By means of approving five energy laws, the Republic of Croatia established an appropriate legislative framework for energy sector regulation. A series of sub-law acts is presently being elaborated as well as some additional documents in order to bring about transparent and non-discriminatory provisions for the establishment of electric energy, gas, oil/oil derivatives and thermal energy markets, i.e. for the introduction and management of market activities and public services. A considerable share of these activities relates to the definition of transparent regulatory mechanisms that would guarantee the implementation of regulation rules based on the law, and be carried out by the independent regulatory body - Croatian Energy Regulatory Council. The Council's rights and obligations include firm executive functions, which present obligations to every energy entity. A dissatisfied party may set in motion a settlement of dispute, if it maintains that the decisions are not based on the law or reveal a flaw in the procedure. Therefore, it is the Council's priority to always make careful and law-abiding decisions. This paper gives insight into the regulatory framework elements based on the laws including the Council's organisational structure and non-profit entities that will prepare act proposals for the Council and perform other professional activities. (author)

  7. 76 FR 60807 - Gulf of Mexico Fishery Management Council; Public Meeting; Correction

    Science.gov (United States)

    2011-09-30

    ... to a Council meeting. SUMMARY: The Gulf of Mexico Fishery Management Council will convene a meeting... Thursday, October 13, 2011. ADDRESSES: The meeting will be held at the Gulf of Mexico Fishery Management Council, 2203 North Lois Avenue, Suite 1100, Tampa, FL 33607. Council address: Gulf of Mexico Fishery...

  8. 75 FR 67688 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-11-03

    ... Pacific Fishery Management Council's (Council's) Ad Hoc Groundfish Essential Fish Habitat Review Committee... groundfish Essential Fish Habitat (EFH). DATES: The work session will be held Monday, December 20, 2010 from...

  9. Clinical Trials

    Medline Plus

    Full Text Available ... Health Topics / About Clinical Trials About Clinical Trials Clinical trials are research studies that explore whether a medical strategy, treatment, ... tool for advancing medical knowledge and patient care. Clinical research is done only if doctors don't know ...

  10. 20 CFR 422.205 - Review by Appeals Council.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Review by Appeals Council. 422.205 Section 422.205 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES Procedures of... the Council. In the event of disagreement between a panel composed of only two members, the Chairman...

  11. Strengthening Africa's science granting councils as champions of ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The capacity strengthening approach will be a participatory one involving customized regional training courses, on-site coaching for individual councils, peer-to-peer learning among councils, and knowledge exchange during annual learning forums. Implementation of this project is expected to contribute to the goals of the ...

  12. 77 FR 46408 - Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-08-03

    ... Pacific Fishery Management Council's (Council) Groundfish Essential Fish Habitat Review Committee (EFHRC... essential fish habitat (EFH). DATES: The conference call will be held August 17, 2012 between 9 a.m. and...

  13. Evaluation of Research in Engineering Science in Norway

    DEFF Research Database (Denmark)

    Van Brussel, Hendrik Van Brussel; Lindberg, Bengt; Cederwall, Klas

    This report presents the conclusions of Panel 1: Construction engineering, Production and Operation. The Research Council of Norway (NFR) appointed three expert panels to evaluate Research in Engineering Science in Norway .......This report presents the conclusions of Panel 1: Construction engineering, Production and Operation. The Research Council of Norway (NFR) appointed three expert panels to evaluate Research in Engineering Science in Norway ....

  14. Citation of prior research has increased in introduction and discussion sections with time: A survey of clinical trials in physiotherapy.

    Science.gov (United States)

    Hoderlein, Xenia; Moseley, Anne M; Elkins, Mark R

    2017-08-01

    Many clinical trials are reported without reference to the existing relevant high-quality research. This study aimed to investigate the extent to which authors of reports of clinical trials of physiotherapy interventions try to use high-quality clinical research to (1) help justify the need for the trial in the introduction and (2) help interpret the trial's results in the discussion. Data were extracted from 221 clinical trials that were randomly selected from the Physiotherapy Evidence Database: 70 published in 2001 (10% sample) and 151 published in 2015 (10% sample). The Physiotherapy Evidence Database score (which rates methodological quality and completeness of reporting) for each trial was also downloaded. Overall 41% of trial reports cited a systematic review or the results of a search for other evidence in the introduction section: 20% for 2001 and 50% for 2015 (relative risk = 2.3, 95% confidence interval = 1.5-3.8). For the discussion section, only 1 of 221 trials integrated the results of the trial into an existing meta-analysis, but citation of a relevant systematic review did increase from 17% in 2001 to 34% in 2015. There was no relationship between citation of existing research and the total Physiotherapy Evidence Database score. Published reports of clinical trials of physiotherapy interventions increasingly cite a systematic review or the results of a search for other evidence in the introduction, but integration with existing research in the discussion section is very rare. To encourage the use of existing research, stronger recommendations to refer to existing systematic reviews (where available) could be incorporated into reporting checklists and journal editorial guidelines.

  15. Northern Land Council v. the Commonwealth

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    The Ranger Project Area in the Northern Territory contains deposits of uranium. By section 5 of the Atomic Energy Amendment Act (No. 2) 1980 the assignment of an agreement between the Commonwealth and joint venturers for the conduct of uranium mining was authorised. The Northern Land Council, representing Aboriginal interests, challenged the validity of the section. It was held that the section was valid. The Council also submitted that, although it had entered into an agreement with the Commonwealth in 1978, the agreement was void or voidable

  16. Implementing falls prevention research into policy and practice in Australia: past, present and future.

    Science.gov (United States)

    Lord, Stephen R; Sherrington, Catherine; Cameron, Ian D; Close, Jacqueline C T

    2011-12-01

    Falls in older Australians are a significant public health issue with one in three older people falling one or more times each year. Many fall prevention randomized controlled trials have been conducted in Australia as well as across the world. The findings of these studies now constitute a substantial evidence base that can provide direction for health and lifestyle interventions for preventing falls in older people. This research evidence has contributed to health policy in Australia to some extent, but is yet to be widely implemented into practice. This opinion piece overviews previous policy initiatives and describes a new Partnership research program funded by the Australian National Health and Medical Research Council (NHMRC), which seeks to further influence health policy and address the ongoing research-practice gap. Copyright © 2011. Published by Elsevier Ltd.

  17. A Review of Barriers to Minorities' Participation in Cancer Clinical Trials: Implications for Future Cancer Research.

    Science.gov (United States)

    Salman, Ali; Nguyen, Claire; Lee, Yi-Hui; Cooksey-James, Tawna

    2016-04-01

    To enhance nurses' awareness and competencies in practice and research by reporting the common barriers to participation of minorities in cancer clinical trials and discussing facilitators and useful strategies for recruitment. Several databases were searched for articles published in peer reviewed journals. Some of the barriers to minorities' participation in clinical trials were identified within the cultural social-context of cancer patients. The involvement of community networking was suggested as the most effective strategy for the recruitment of minorities in cancer clinical trials. Using culturally sensitive approaches to enhance ethnic minorities' participation is important for advancing cancer care and eliminating health disparities. Awareness of barriers and potential facilitators to the enrollment of ethnic minority cancer patients may contribute to enhancing nurses' competencies of recruiting ethnic minorities in nursing research, playing efficient roles in cancer clinical trials team, and providing culturally competent quality care.

  18. The TLRR II – Providing Digital Infrastructure to Research Roman Republican Trials

    Directory of Open Access Journals (Sweden)

    Kirsten Jahn

    2016-12-01

    Full Text Available The project Trials in the Late Roman Republic II (TLRR II aims at collecting, organizing, and analyzing information about Roman legal cases in an XML database. M. Alexander published the book “Trials in the Late Roman Republic, 149 BC to 50 BC” (TLRR I in 1990, and initiated the current project that will make Roman republican trials easily accessible with modern technology. For each case a short description is provided, a clear distinction between assumptions and facts is made, and an updated bibliography can be found at the end of each entry. The open access database can serve both as a reference work and as a starting point for further research in Roman Republican history. It could be a connecting link within the developing digital infrastructure for that era.

  19. 78 FR 13867 - Mid-Atlantic Fishery Management Council (MAFMC); Public Meeting

    Science.gov (United States)

    2013-03-01

    ...: The Mid-Atlantic Fishery Management Council's Scientific and Statistical Committee (SSC) will hold a... Fishery Management Council (MAFMC); Public Meeting AGENCY: National Marine Fisheries Service (NMFS... address: Mid-Atlantic Fishery Management Council, 800 North State Street, Suite 201, Dover, DE 19901...

  20. Utility of Recent Studies to Assess the National Research Council 2001 Estimates of Cancer Risk from Ingested Arsenic

    Science.gov (United States)

    Gibb, Herman; Haver, Cary; Gaylor, David; Ramasamy, Santhini; Lee, Janice S.; Lobdell, Danelle; Wade, Timothy; Chen, Chao; White, Paul; Sams, Reeder

    2011-01-01

    Objective The purpose of this review is to evaluate the impact of recent epidemiologic literature on the National Research Council (NRC) assessment of the lung and bladder cancer risks from ingesting low concentrations (ecologic nature of the Taiwanese studies on which the NRC estimates are based present certain limitations, the data from these studies have particular strengths in that they describe lung and bladder cancer risks resulting from lifetime exposure in a large population and remain the best data on which to conduct quantitative risk assessment. Continued follow-up of a population in northeastern Taiwan, however, offers the best opportunity to improve the cancer risk assessment for arsenic in drinking water. Future studies of arsenic < 100 μg/L in drinking water and lung and bladder cancer should consider adequacy of the sample size, the synergistic relationship of arsenic and smoking, duration of arsenic exposure, age when exposure began and ended, and histologic subtype. PMID:21030336