WorldWideScience

Sample records for reported large gains

  1. Leading Gainful Employment Metric Reporting

    Science.gov (United States)

    Powers, Kristina; MacPherson, Derek

    2016-01-01

    This chapter will address the importance of intercampus involvement in reporting of gainful employment student-level data that will be used in the calculation of gainful employment metrics by the U.S. Department of Education. The authors will discuss why building relationships within the institution is critical for effective gainful employment…

  2. The Flynn effect in Korea: Large gains

    NARCIS (Netherlands)

    te Nijenhuis, J.; Cho, S.H.; Murphy, R.; Lee, K.H.

    2012-01-01

    Secular gains in IQ test scores have been reported for many Western countries. This is the first study of secular IQ gains in South Korea, using various datasets. The first question is what the size of the Flynn effect in South Korea is. The gains per decade are 7.7 points for persons born between 1

  3. The Flynn effect in Korea: Large gains

    NARCIS (Netherlands)

    te Nijenhuis, J.; Cho, S.H.; Murphy, R.; Lee, K.H.

    2012-01-01

    Secular gains in IQ test scores have been reported for many Western countries. This is the first study of secular IQ gains in South Korea, using various datasets. The first question is what the size of the Flynn effect in South Korea is. The gains per decade are 7.7 points for persons born between

  4. GAIN Technology Workshops Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Braase, Lori Ann [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-08-01

    National and global demand for nuclear energy is increasing and United States (U.S.) global leadership is eroding. There is a sense of urgency with respect to the deployment of the innovative nuclear energy technologies. The Gateway for Accelerated Innovation in Nuclear (GAIN) initiative is based on the simultaneous achievement of three strategic goals. The first is maintaining global technology leadership within the U.S. Department of Energy (DOE). The second is enabling global industrial leadership for nuclear vendors and suppliers. The third is focused on utility optimization of nuclear energy within the clean energy portfolio. An effective public-private partnership is required to achieve these goals. DOEs recognizes the recent sense of urgency new developers and investors have in getting their concepts to market. They know that time to market for nuclear technology takes too long and the facilities needed to conduct the necessary research, development and demonstration (RD&D) activities are very expensive to develop and maintain. Early technologies, in the lower technology readiness levels (TRL) need materials testing, analysis, modeling, code development, etc., most of which currently exists in the DOE national laboratory system. However, mature technologies typically need large component testing and demonstration facilities, which are expensive and long-lead efforts. By understanding the needs of advanced nuclear technology developers, GAIN will connect DOE national laboratory capabilities (e.g., facilities, expertise, materials, and data) with industry RD&D needs. In addition, GAIN is working with the Nuclear Regulatory Commission (NRC) to streamline processes and increase understanding of the licensing requirements for advanced reactors.

  5. Beyond Multiplexing Gain in Large MIMO Systems

    DEFF Research Database (Denmark)

    Cakmak, Burak; Müller, Ralf R.; Fleury, Bernard Henri

    Given the common technical assumptions in the literature on MIMO channel modeling, we derive generic results for MIMO systems in the large system limit LSL. Consider a $\\ phi T\\ times T $ MIMO system with $ T $ tending to infinity. By increasing the antenna ratio $\\ phi $ when $\\ phi\\ geq 1$, the...

  6. Beyond Multiplexing Gain in Large MIMO Systems

    DEFF Research Database (Denmark)

    Cakmak, Burak; Müller, Ralf R.; Fleury, Bernard Henri

    Given the common technical assumptions in the literature on MIMO channel modeling, we derive generic results for MIMO systems in the large system limit LSL. Consider a $\\ phi T\\ times T $ MIMO system with $ T $ tending to infinity. By increasing the antenna ratio $\\ phi $ when $\\ phi\\ geq 1$, the...

  7. Robust Optimal Adaptive Control Method with Large Adaptive Gain

    Science.gov (United States)

    Nguyen, Nhan T.

    2009-01-01

    In the presence of large uncertainties, a control system needs to be able to adapt rapidly to regain performance. Fast adaptation is referred to the implementation of adaptive control with a large adaptive gain to reduce the tracking error rapidly. However, a large adaptive gain can lead to high-frequency oscillations which can adversely affect robustness of an adaptive control law. A new adaptive control modification is presented that can achieve robust adaptation with a large adaptive gain without incurring high-frequency oscillations as with the standard model-reference adaptive control. The modification is based on the minimization of the Y2 norm of the tracking error, which is formulated as an optimal control problem. The optimality condition is used to derive the modification using the gradient method. The optimal control modification results in a stable adaptation and allows a large adaptive gain to be used for better tracking while providing sufficient stability robustness. Simulations were conducted for a damaged generic transport aircraft with both standard adaptive control and the adaptive optimal control modification technique. The results demonstrate the effectiveness of the proposed modification in tracking a reference model while maintaining a sufficient time delay margin.

  8. Laterally periodic resonator for large-area gain lasers.

    Science.gov (United States)

    Feng, Yan; Ueda, Ken-Ichi

    2003-03-24

    Laterally periodic resonators, which can be constructed by use of transversely periodic phase- or amplitude-modulating elements in a cavity, are proposed for stabilization and generation of transversely coherent output from large-area gain. Lasers with periodic resonators have the combined features of conventional cavities and laser arrays. Significant low-order transverse modes and mode discrimination of a sample resonator with intracavity periodic phase elements are investigated numerically by the iteration method. Wave-propagation calculations are carried out by use of a fast Fourier transform, and a modified Prony method is used to evaluate wave functions and losses of transverse modes. Results of numerical calculations are consistent with expectations.

  9. Large conservation gains possible for global biodiversity facets

    Science.gov (United States)

    Pollock, Laura J.; Thuiller, Wilfried; Jetz, Walter

    2017-06-01

    Different facets of biodiversity other than species numbers are increasingly appreciated as critical for maintaining the function of ecosystems and their services to humans. While new international policy and assessment processes such as the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) recognize the importance of an increasingly global, quantitative and comprehensive approach to biodiversity protection, most insights are still focused on a single facet of biodiversity—species. Here we broaden the focus and provide an evaluation of how much of the world’s species, functional and phylogenetic diversity of birds and mammals is currently protected and the scope for improvement. We show that the large existing gaps in the coverage for each facet of diversity could be remedied by a slight expansion of protected areas: an additional 5% of the land has the potential to more than triple the protected range of species or phylogenetic or functional units. Further, the same areas are often priorities for multiple diversity facets and for both taxa. However, we find that the choice of conservation strategy has a fundamental effect on outcomes. It is more difficult (that is, requires more land) to maximize basic representation of the global biodiversity pool than to maximize local diversity. Overall, species and phylogenetic priorities are more similar to each other than they are to functional priorities, and priorities for the different bird biodiversity facets are more similar than those of mammals. Our work shows that large gains in biodiversity protection are possible, while also highlighting the need to explicitly link desired conservation objectives and biodiversity metrics. We provide a framework and quantitative tools to advance these goals for multi-faceted biodiversity conservation.

  10. Towards a large-scale European Naturalistic Driving study : final report of PROLOGUE. PROmoting real Life Observations for Gaining Understanding of road user behaviour in Europe PROLOGUE, Deliverable D4.2.

    NARCIS (Netherlands)

    Schagen, I.N.L.G. van Welsh, R. Backer-Grøndahl, A. Hoedemaeker, M. Lotan, T. Morris, A. Sagberg, F. & Winkelbauer, M.

    2011-01-01

    This report is the final report of the PROLOGUE project. It provides a concise overview of the main findings of the project in its aim to assess the usefulness and feasibility of a large-scale European Naturalistic Driving (ND) study. Successively, the report discusses the most important information

  11. Large Size Telescope Report

    CERN Document Server

    Mazin, D; Teshima, M

    2016-01-01

    The Cherenkov Telescope Array (CTA) observatory will be deployed over two sites in the two hemispheres. Both sites will be equipped with four Large Size Telescopes (LSTs), which are crucial to achieve the science goals of CTA in the 20-200 GeV energy range. Each LST is equipped with a primary tessellated mirror dish of 23 m diameter, supported by a structure made mainly of carbon fibre reinforced plastic tubes and aluminum joints. This solution guarantees light weight (around 100 tons), essential for fast repositioning to any position in the sky in <20 seconds. The camera is composed of 1855 photomultiplier tubes and embeds the control, readout and trigger electronics. The detailed design is now complete and production of the first LST, which will serve as a prototype for the remaining seven, is ongoing. The installation of the first LST at the Roque de los Muchachos Observatory on the Canary island of La Palma (Spain) started in July 2016. In this paper we will outline the technical solutions adopted to f...

  12. Large size telescope report

    Science.gov (United States)

    Mazin, D.; Cortina, J.; Teshima, M.

    2017-01-01

    The Cherenkov Telescope Array (CTA) observatory will be deployed over two sites in the two hemispheres. Both sites will be equipped with four Large Size Telescopes (LSTs), which are crucial to achieve the science goals of CTA in the 20-200 GeV energy range. Each LST is equipped with a primary tessellated mirror dish of 23 m diameter, supported by a structure made mainly of carbon fibre reinforced plastic tubes and aluminum joints. This solution guarantees light weight (around 100 tons), essential for fast repositioning to any position in the sky in <20 seconds. The camera is composed of 1855 photomultiplier tubes and embeds the control, readout and trigger electronics. The detailed design is now complete and production of the first LST, which will serve as a prototype for the remaining seven, is ongoing. The installation of the first LST at the Roque de los Muchachos Observatory on the Canary island of La Palma (Spain) started in July 2016. In this paper we will outline the technical solutions adopted to fulfill the design requirements, present results of element prototyping and describe the installation and operation plans.

  13. Tailoring the parametric gain in large mode area hybrid photonic crystal fibers

    DEFF Research Database (Denmark)

    Petersen, Sidsel Rübner; Lægsgaard, Jesper; Alkeskjold, Thomas Tanggaard

    2013-01-01

    The spectral width of parametric gain peaks due to degenerate four-wave mixing is investigated numerically in large-mode-area hybrid photonic crystal fibers. The width is varied for a maintained pump wavelength and gain maximum position by tailoring the dispersion.......The spectral width of parametric gain peaks due to degenerate four-wave mixing is investigated numerically in large-mode-area hybrid photonic crystal fibers. The width is varied for a maintained pump wavelength and gain maximum position by tailoring the dispersion....

  14. Tailoring the parametric gain in large mode areahybrid photonic crystal fibers

    DEFF Research Database (Denmark)

    Petersen, Sidsel Rübner; Lægsgaard, Jesper; Alkeskjold, Thomas Tanggaard

    2013-01-01

    The spectral width of parametric gain peaks due to degenerate four-wave mixing is investigated numerically in large-mode-area hybrid photonic crystal fibers. The width is varied for a maintained pump wavelength and gain maximum position by tailoring the dispersion.......The spectral width of parametric gain peaks due to degenerate four-wave mixing is investigated numerically in large-mode-area hybrid photonic crystal fibers. The width is varied for a maintained pump wavelength and gain maximum position by tailoring the dispersion....

  15. A Nonlinear Small-Gain Theorem for Large-Scale Time Delay Systems

    CERN Document Server

    Tiwari, Shanaz; Jiang, Zhong-Ping

    2009-01-01

    This paper extends the nonlinear ISS small-gain theorem to a large-scale time delay system composed of three or more subsystems. En route to proving this small-gain theorem for systems of differential equations with delays, a small-gain theorem for operators is examined. The result developed for operators allows applications to a wide class of systems, including state space systems with delays.

  16. Study on Dielectric Resonator Antenna with Annular Patch for High Gain and Large Bandwidth

    Institute of Scientific and Technical Information of China (English)

    FENG Kuisheng; LI Na; MENG Qingwei; WANG Yongfeng; ZHANG Jingwei

    2015-01-01

    A new high-gain cylindrical Dielectric res-onator antenna (DRA) with a large bandwidth is proposed. A cylindrical Dielectric resonator (DR), a double-annular patch and a metallic cylinder are used to obtain a large bandwidth and a high gain. The mode TM12 excited in the patch is used to enhance the gain of the DRA, and the cavity formed by the metallic cylinder provides a further higher gain and a larger bandwidth. The measured results demonstrate that the proposed DRA achieves a large band-width of 23%from 5.3 to 6.8GHz with VSWR less than two and a high gain around 11 dBi.

  17. Approximate theory of Stokes amplification and conversion valid at large gain

    Energy Technology Data Exchange (ETDEWEB)

    Druehl, K.J.; Shakir, S.; Yousaf, M.

    1986-07-01

    We predict Stokes-beam divergence, origin, and gain for large-gain Raman amplifiers as functions of pump-beam divergence and pump power in terms of simple analytical expressions. Stokes divergence is found to peak at a pump power twice above threshold. Results are in excellent agreement with exact computer solutions and explain recent experimental observations.

  18. Tailoring the parametric gain in large mode areahybrid photonic crystal fibers

    OpenAIRE

    Petersen, Sidsel Rübner; Lægsgaard, Jesper; Alkeskjold, Thomas Tanggaard

    2013-01-01

    The spectral width of parametric gain peaks due to degenerate four-wave mixing is investigated numerically in large-mode-area hybrid photonic crystal fibers. The width is varied for a maintained pump wavelength and gain maximum position by tailoring the dispersion.

  19. Large electroabsorption susceptibility mediated by internal photoconductive gain in Ge nanowires.

    Science.gov (United States)

    Lee, Hyun-Seung; Kim, Cheol-Joo; Lee, Donghun; Lee, Ru Ri; Kang, Kibum; Hwang, Inchan; Jo, Moon-Ho

    2012-11-14

    Large spectral modulation in the photon-to-electron conversion near the absorption band-edge of a semiconductor by an applied electrical field can be a basis for efficient electro-optical modulators. This electro-absorption effect in Group IV semiconductors is, however, inherently weak, and this poses the technological challenges for their electro-photonic integration. Here we report unprecedentedly large electro-absorption susceptibility at the direct band-edge of intrinsic Ge nanowire (NW) photodetectors, which is strongly diameter-dependent. We provide evidence that the large spectral shift at the 1.55 μm wavelength, enhanced up to 20 times larger than Ge bulk crystals, is attributed to the internal Franz-Keldysh effect across the NW surface field of ~10(5) V/cm, mediated by the strong photoconductive gain. This classical size-effect operating at the nanometer scale is universal, regardless of the choice of materials, and thus suggests general implications for the monolithic integration of Group IV photonic circuits.

  20. Approaching Quantum-Limited Amplification with Large Gain Catalyzed by Optical Parametric Amplifier Medium

    Science.gov (United States)

    Zheng, Qiang; Li, Kai

    2017-07-01

    Amplifier is at the heart of experiments carrying out the precise measurement of a weak signal. An idea quantum amplifier should have a large gain and minimum added noise simultaneously. Here, we consider the quantum measurement properties of the cavity with the OPA medium in the op-amp mode to amplify an input signal. We show that our nonlinear-cavity quantum amplifier has large gain in the single-value stable regime and achieves quantum limit unconditionally. Supported by the National Natural Science Foundation of China under Grant Nos. 11365006, 11364006, and the Natural Science Foundation of Guizhou Province QKHLHZ [2015]7767

  1. Light amplification at 501 nm and large nanosecond optical gain in organic dye-doped polymeric waveguides

    Science.gov (United States)

    Jordan, Grace; Flämmich, Michael; Rüther, Manuel; Kobayashi, Takeyuki; Blau, Werner J.; Suzuki, Yasuhiro; Kaino, Toshikuni

    2006-04-01

    We report on the results of a gain measurement on a substituted stilbene-dye-doped polymer waveguide operating in the blue-green spectral region. By monitoring amplified spontaneous emission from the waveguides under nanosecond photopumping, we deduced net modal gain as large as 84±6cm-1 at 501nm, the peak of the gain spectrum, when pumped with a fluence of 1.1mJ/cm2. Moreover, the effective stimulated emission cross section of 2.7×10-16cm2 and the loss coefficient of 0.3cm-1 at 501nm are extracted. The transparency pump fluence and the corresponding excited state population density are found to be 17μJ/cm2 and 8.8×1015cm-3 which is approximately 0.1% of total population, respectively. Comparison is made with other organic and inorganic gain media operating in the short wavelength (violet-green) region of the spectrum. We demonstrate that small-molecule-doped polymers show large gain, comparable with those in conjugated polymers and dendrimers.

  2. Steady State Analysis of Short-wavelength, High-gainFELs in a Large Storage Ring

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Z.; Bane, K.; Cai, Y.; Chao, A.; Hettel, R.; /SLAC; Pellegrini, C.; /UCLA

    2007-10-15

    Storage ring FELs have operated successfully in the low-gain regime using optical cavities. Discussions of a high-gain FEL in a storage ring typically involve a special bypass to decouple the FEL interaction from the storage ring dynamics. In this paper, we investigate the coupled dynamics of a high-gain FEL in a large storage ring such as PEP and analyze the equilibrium solution. We show that an FEL in the EUV and soft x-ray regimes can be integrated into a very bright storage ring and potentially provides three orders of magnitude improvement in the average brightness at these radiation wavelengths. We also discuss possibilities of seeding with HHG sources to obtain ultra-short, high-peak power EUV and soft x-ray pulses.

  3. Large Block Test Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Lin, W

    2001-12-01

    This report documents the Large-Block Test (LBT) conducted at Fran Ridge near Yucca Mountain, Nevada. The LBT was a thermal test conducted on an exposed block of middle non-lithophysal Topopah Spring tuff (Tptpmn) and was designed to assist in understanding the thermal-hydrological-mechanical-chemical (THMC) processes associated with heating and then cooling a partially saturated fractured rock mass. The LBT was unique in that it was a large (3 x 3 x 4.5 m) block with top and sides exposed. Because the block was exposed at the surface, boundary conditions on five of the six sides of the block were relatively well known and controlled, making this test both easier to model and easier to monitor. This report presents a detailed description of the test as well as analyses of the data and conclusions drawn from the test. The rock block that was tested during the LBT was exposed by excavation and removal of the surrounding rock. The block was characterized and instrumented, and the sides were sealed and insulated to inhibit moisture and heat loss. Temperature on the top of the block was also controlled. The block was heated for 13 months, during which time temperature, moisture distribution, and deformation were monitored. After the test was completed and the block cooled down, a series of boreholes were drilled, and one of the heater holes was over-cored to collect samples for post-test characterization of mineralogy and mechanical properties. Section 2 provides background on the test. Section 3 lists the test objectives and describes the block site, the site configuration, and measurements made during the test. Section 3 also presents a chronology of events associated with the LBT, characterization of the block, and the pre-heat analyses of the test. Section 4 describes the fracture network contained in the block. Section 5 describes the heating/cooling system used to control the temperature in the block and presents the thermal history of the block during the test

  4. Clinical tolerance in large field radiotherapy--the knowledge gained over the last ten years.

    Science.gov (United States)

    Gocheva, Lilia B

    2010-01-01

    Malignant disorders are still far from being successfully managed in spite of the apparent progress achieved by surgical treatment, high energy radiotherapy (RT) and chemotherapy (CHT). They keep being the second most frequent cause of lethal outcomes both in Bulgaria and in most countries of the world. One of the promising approaches to increasing the efficaciousness of treatment is development and use of methods that are in full accord with the modern requirements of a complex therapy. Over the last fifty years, large field radiation techniques, applied as systemic therapy in oncology, have been investigated and established. These techniques show the transition in oncology to using actively various variants of large field radiotherapy (LFR), the "heavy artillery" of oncoradiologic practice, as an alternative or adjunct therapy to chemotherapy (CHT). In the present paper we review the current knowledge in the field and present the clinical experience accumulated over the last ten years with respect to clinical tolerance in the major large-field radiotherapy techniques--total body irradiation, half body irradiation, whole abdominal irradiation, total and partial lymphoid irradiation. Described in detail are the contemporary knowledge about clinical and hematologic tolerance in total body irradiation as part of the myelo- and nonmyeloablative conditioning regimens as well as in half body irradiation as a systemic therapy in oncology. We also present the amassed experience in clinical tolerance in partial body irradiation in the form of whole abdominal and total or partial lymphoid irradiation. Another point worth noting based again on the experience gained over the last ten years is that for LFR we need to develop a radiotherapy technique that is designed carefully to achieve an optimal therapeutic effect that should include the disease control, good clinical tolerance and reduction of post-radiotherapy sequelae.

  5. Large gain in air quality compared to an alternative anthropogenic emissions scenario

    Science.gov (United States)

    Daskalakis, Nikos; Tsigaridis, Kostas; Myriokefalitakis, Stelios; Fanourgakis, George S.; Kanakidou, Maria

    2016-08-01

    During the last 30 years, significant effort has been made to improve air quality through legislation for emissions reduction. Global three-dimensional chemistry-transport simulations of atmospheric composition over the past 3 decades have been performed to estimate what the air quality levels would have been under a scenario of stagnation of anthropogenic emissions per capita as in 1980, accounting for the population increase (BA1980) or using the standard practice of neglecting it (AE1980), and how they compare to the historical changes in air quality levels. The simulations are based on assimilated meteorology to account for the year-to-year observed climate variability and on different scenarios of anthropogenic emissions of pollutants. The ACCMIP historical emissions dataset is used as the starting point. Our sensitivity simulations provide clear indications that air quality legislation and technology developments have limited the rapid increase of air pollutants. The achieved reductions in concentrations of nitrogen oxides, carbon monoxide, black carbon, and sulfate aerosols are found to be significant when comparing to both BA1980 and AE1980 simulations that neglect any measures applied for the protection of the environment. We also show the potentially large tropospheric air quality benefit from the development of cleaner technology used by the growing global population. These 30-year hindcast sensitivity simulations demonstrate that the actual benefit in air quality due to air pollution legislation and technological advances is higher than the gain calculated by a simple comparison against a constant anthropogenic emissions simulation, as is usually done. Our results also indicate that over China and India the beneficial technological advances for the air quality may have been masked by the explosive increase in local population and the disproportional increase in energy demand partially due to the globalization of the economy.

  6. Large Gain in Air Quality Compared to an Alternative Anthropogenic Emissions Scenario

    Science.gov (United States)

    Daskalakis, Nikos; Tsigaridis, Kostas; Myriokefalitakis, Stelios; Fanourgakis, George S.; Kanakidou, Maria

    2016-01-01

    During the last 30 years, significant effort has been made to improve air quality through legislation for emissions reduction. Global three-dimensional chemistrytransport simulations of atmospheric composition over the past 3 decades have been performed to estimate what the air quality levels would have been under a scenario of stagnation of anthropogenic emissions per capita as in 1980, accounting for the population increase (BA1980) or using the standard practice of neglecting it (AE1980), and how they compare to the historical changes in air quality levels. The simulations are based on assimilated meteorology to account for the yearto- year observed climate variability and on different scenarios of anthropogenic emissions of pollutants. The ACCMIP historical emissions dataset is used as the starting point. Our sensitivity simulations provide clear indications that air quality legislation and technology developments have limited the rapid increase of air pollutants. The achieved reductions in concentrations of nitrogen oxides, carbon monoxide, black carbon, and sulfate aerosols are found to be significant when comparing to both BA1980 and AE1980 simulations that neglect any measures applied for the protection of the environment. We also show the potentially large tropospheric air quality benefit from the development of cleaner technology used by the growing global population. These 30-year hindcast sensitivity simulations demonstrate that the actual benefit in air quality due to air pollution legislation and technological advances is higher than the gain calculated by a simple comparison against a constant anthropogenic emissions simulation, as is usually done. Our results also indicate that over China and India the beneficial technological advances for the air quality may have been masked by the explosive increase in local population and the disproportional increase in energy demand partially due to the globalization of the economy.

  7. Giant photon gain in large-scale quantum dot circuit-QED systems

    CERN Document Server

    Agarwalla, Bijay Kumar; Mukamel, Shaul; Segal, Dvira

    2016-01-01

    Motivated by recent experiments on the generation of coherent light in engineered hybrid quantum systems, we investigate gain in a microwave photonic cavity coupled to quantum dot structures, and develop concrete directions for achieving a giant amplification in photon transmission. We propose two architectures for scaling up the electronic gain medium: (i) $N$ double quantum dot systems (N-DQD), (ii) $M$ quantum dots arranged in series akin to a quantum cascade laser setup. In both setups, the fermionic reservoirs are voltage biased, and the quantum dots are coupled to a single-mode cavity. Optical amplification is explained based on a sum rule for the transmission function, and it is determined by an intricate competition between two different processes: charge density response in the gain medium, and cavity losses to input and output ports. The same design principle is also responsible for the corresponding giant amplification in other photonic observables, mean photon number and emission spectrum, thereby...

  8. Gaining A Geological Perspective Through Active Learning in the Large Lecture Classroom

    Science.gov (United States)

    Kapp, J. L.; Richardson, R. M.; Slater, S. J.

    2008-12-01

    NATS 101 A Geological Perspective is a general education course taken by non science majors. We offer 600 seats per semester, with four large lecture sections taught by different faculty members. In the past we have offered optional once a week study groups taught by graduate teaching assistants. Students often feel overwhelmed by the science and associated jargon, and many are prone to skipping lectures altogether. Optional study groups are only attended by ~50% of the students. Faculty members find the class to be a lot of work, mainly due to the grading it generates. Activities given in lecture are often short multiple choice or true false assignments, limiting the depth of understanding we can evaluate. Our students often lack math and critical thinking skills, and we spend a lot of time in lecture reintroducing ideas students should have already gotten from the text. In summer 2007 we were funded to redesign the course. Our goals were to 1) cut the cost of running the course, and 2) improve student learning. Under our redesign optional study groups were replaced by once a week mandatory break out sessions where students complete activities that have been introduced in lecture. Break out sessions substitute for one hour of lecture, and are run by undergraduate preceptors and graduate teaching assistants (GTAs). During the lecture period, lectures themselves are brief with a large portion of the class devoted to active learning in small groups. Weekly reading quizzes are submitted via the online course management system. Break out sessions allow students to spend more time interacting with their fellow students, undergraduate preceptors, and GTAs. They get one on one help in break out sessions on assignments designed to enhance the lecture material. The active lecture format means less of their time is devoted to listening passively to a lecture, and more time is spent peer learning an interacting with the instructor. Completing quizzes online allows students

  9. Large erupting complex odontoma: a case report.

    Science.gov (United States)

    Vengal, Manoj; Arora, Honey; Ghosh, Sujoy; Pai, Keerthilatha M

    2007-03-01

    Odontomas are the most common odontogenic tumours. They are usually asymptomatic and are often discovered during routine radiography. We report a case of a large erupting complex odontoma that caused pain, infection and facial asymmetry. This case is significant as there are few reports of complex odontoma erupting in the oral cavity.

  10. Ytterbium-doped large-mode-area photonic crystal fiber amplifier with gain shaping for use at long wavelengths

    DEFF Research Database (Denmark)

    Petersen, Sidsel Rübner; Alkeskjold, Thomas T.; Poli, Federica

    2012-01-01

    A large-mode-area Ytterbium-doped photonic crystal fiber amplifier with efficient suppression of amplified spontaneous emission is presented. The fiber cladding consists of a hexagonal lattice of air holes, where three rows are replaced with circular high-index inclusions. Seven missing air holes...... wavelength regime of the Ytterbium gain spectrum above 1100 nm....

  11. Delta: a charge sensitive front-end amplifier with switched gain for low-noise, large dynamic range silicon detector readout

    NARCIS (Netherlands)

    Aspell, P.; Barney, D.; Bloch, P.; Jarron, P.; Lofstedt, B.; Reynaud, S.; Tabbers, P.

    2001-01-01

    The design and results of a radiation hard switched gain charge amplifier optimised for a large dynamic range and large input capacitance are described. The peaking time is 25 ns, dynamic ranges are 0.1–50 minimum ionising particles (MIPs) (high gain) and 1–400 MIPs (low gain), signal to noise (S/N)

  12. Large delay tunable slow-light based on high-gain stimulated-Brillouin-scattering amplification in optical fibers

    Institute of Scientific and Technical Information of China (English)

    XING Liang; ZHAN Li; XIA YuXing

    2009-01-01

    Tunable stimulated-Brillouin-scattering (SBS)-based slow-light in optical fibers has potential applications in optical buffering in the future all-optical router commutation systems.However,due to the low SBS threshold and relatively high realistic signal power,the gain in the usual SBS systems is limited at~30 dB.This paper presents a high-gain SBS scheme to realize large delay slow-light,which benefits from avoiding the depletion of the pump power in a short fiber as SBS media.The experiment demon strates that,up to 50 dB non-saturated gain has been observed in the single-stage 591.8 m fiber SBS amplification.The slow-light delay can be obtained 52 ns,and the fractional delay can exceed 1.

  13. The Value-Added Achievement Gains of NBPTS-Certified Teachers in Tennessee: A Brief Report.

    Science.gov (United States)

    Stone, J. E.

    This study investigated whether National Board for Professional Teaching Standards (NBPTS)-certified teachers in Tennessee were exceptionally effective in bringing about objectively measured student achievement gains. Tennessee has over 40 NBPTS-certified teachers, 16 of whom teach in grades 3-8 and have value-added teacher reports in the state…

  14. Weight Gain While Switching from Polypharmacy to Ziprasidone: A Case Report.

    Science.gov (United States)

    Lee, Chin-Pang; Chen, Alice Pei-Jung; Juang, Yeong-Yuh

    2015-01-01

    Second-generation antipsychotics (SGAs), valproate, and sulpiride are related to significant weight gain and risk of metabolic syndrome (MetS). Among SGAs, olanzapine and clozapine are associated with the highest metabolic risk while ziprasidone is among one of the SGAs with the lowest risk. Several reports suggest that weight loss is observed in switching other antipsychotics to ziprasidone. Here we describe a female patient with chronic paranoid schizophrenia who had an unexpected weight gain and developed MetS during a cross-switch from a polypharmacy of olanzapine, valproate and sulpiride to ziprasidone monotherapy.

  15. Intermodal parametric gain of degenerate four wave mixing in large mode area hybrid photonic crystal fibers

    OpenAIRE

    Petersen, Sidsel Rübner; Lægsgaard, Jesper; Alkeskjold, Thomas Tanggaard

    2013-01-01

    Intermodal degenerate four wave mixing (FWM) is investigated numerically in large mode area hybrid photonic crystal fibers. The dispersion is controlled independently of core size, and thus allows for power scaling of the FWM process.

  16. Intermodal parametric gain of degenerate four wave mixing in large mode area hybrid photonic crystal fibers

    DEFF Research Database (Denmark)

    Petersen, Sidsel Rübner; Lægsgaard, Jesper; Alkeskjold, Thomas Tanggaard

    2013-01-01

    Intermodal degenerate four wave mixing (FWM) is investigated numerically in large mode area hybrid photonic crystal fibers. The dispersion is controlled independently of core size, and thus allows for power scaling of the FWM process.......Intermodal degenerate four wave mixing (FWM) is investigated numerically in large mode area hybrid photonic crystal fibers. The dispersion is controlled independently of core size, and thus allows for power scaling of the FWM process....

  17. Energy Efficiency Gain of Cellular Base Stations with Large-Scale Antenna Systems for Green Information and Communication Technology

    Directory of Open Access Journals (Sweden)

    Byung Moo Lee

    2017-06-01

    Full Text Available Due to the ever-increasing data demand of end users, the number of information and communication technology (ICT-related devices and equipment continues to increase. This induces large amounts of heat emissions, which can cause serious environmental pollution. In recent times, signal transmission systems such as cellular base stations (BSs have been constructed everywhere and these emit a large carbon footprint. Large-scale antenna systems (LSASs that use a large amount of transmission antennas to serve a limited number of users can increase energy efficiency (EE of BSs based on the beamforming effect, and thus can be a promising candidate to reduce the carbon footprint of the ICT field. In this paper, we discuss the necessary schemes to realize LSASs and show the expected EE gain of the LSAS with enough practicality. There are many obstacles to realize the high EE LSAS, and even though several studies have shown separate schemes to increase the EE and/or throughput (TP of LSASs, few have shown combinations of schemes, and presented how much EE gain can be achieved by the schemes in the overall system. Based on the analysis in this paper, we believe more detailed work for the realization of high energy efficient BSs with LSASs is possible because this paper shows the necessary schemes and the maximum achievable energy efficiency gain as a reference. Extensive analysis and simulation results show that with proper implementation of the power amplifier/RF module and a robust channel estimation scheme, LSASs with 600 transmitter (TX antennas can achieve 99.4 times more EE gain compared to the current systems, thereby resulting in significant reduction of carbon footprints.

  18. Gaining Insight into Microbial Physiology in the Large Intestine: A Special Role for Stable Isotopes

    NARCIS (Netherlands)

    Graaf, A.A. de; Venema, K.

    2008-01-01

    The importance of the human large intestine for nutrition, health, and disease, is becoming increasingly realized. There are numerous indications of a distinct role for the gut in such important issues as immune disorders and obesity-linked diseases. Research on this long-neglected organ, which is

  19. Preventing large birth size in women with preexisting diabetes mellitus: The benefit of appropriate gestational weight gain

    Science.gov (United States)

    Kim, Shin Y.; Sharma, Andrea J.; Sappenfield, William; Salihu, Hamisu M.

    2016-01-01

    Objective To estimate the percentage of infants with large birth size attributable to excess gestational weight gain (GWG), independent of prepregnancy body mass index, among mothers with preexisting diabetes mellitus (PDM). Study design We analyzed 2004–2008 Florida linked birth certificate and maternal hospital discharge data of live, term (37–41 weeks) singleton deliveries (N = 641,857). We calculated prevalence of large-for-gestational age (LGA) (birth weight-for-gestational age ≥ 90th percentile) and macrosomia (birth weight > 4500 g) by GWG categories (inadequate, appropriate, or excess). We used multivariable logistic regression to estimate the relative risk (RR) of large birth size associated with excess compared to appropriate GWG among mothers with PDM. We then estimated the population attributable fraction (PAF) of large birth size due to excess GWG among mothers with PDM (n = 4427). Results Regardless of diabetes status, half of mothers (51.2%) gained weight in excess of recommendations. Large birth size was higher in infants of mothers with PDM than in infants of mothers without diabetes (28.8% versus 9.4% for LGA, 5.8% versus 0.9% for macrosomia). Among women with PDM, the adjusted RR of having an LGA infant was 1.7 (95% CI 1.5, 1.9) for women with excess GWG compared to those with appropriate gain; the PAF was 27.7% (95% CI 22.0, 33.3). For macrosomia, the adjusted RR associated with excess GWG was 2.1 (95% CI 1.5, 2.9) and the PAF was 38.6% (95% CI 24.9, 52.4). Conclusion Preventing excess GWG may avert over one-third of macrosomic term infants of mothers with PDM. Effective strategies to prevent excess GWG are needed. PMID:27539071

  20. Gain-guided index-antiguided fiber with a Fabry-Perot layer for large mode area laser amplifiers.

    Science.gov (United States)

    Lai, Chih-Hsien; Chen, Hsuan-Yu; Du, Cheng-Han; Chiou, Yih-Peng

    2015-02-23

    We propose a modified gain-guided index-antiguided (GGIAG) fiber structure for large mode area laser amplifiers, in which a thin dielectric layer is placed between the low-index core and the high-index cladding. The introduced dielectric layer functions as a Fabry-Perot etalon. By letting the resonant wavelength of the Fabry-Perot layer coincide with the signal wavelength, the signal is gain-guided in the fiber core. Moreover, the pump is confined in the low-index core owing to the antiresonant reflection originated from the Fabry-Perot layer. Numerical results indicate that the leakage loss of the pump can be minified over two orders of magnitude in the proposed structure, and thus the end-pumping efficiency could be enhanced significantly.

  1. Challenges in Gaining Large Scale Carbon Reductions through Wireless Home Automation Systems

    DEFF Research Database (Denmark)

    Larsen, Peter Gorm; Rovsing, Poul Ejnar; Toftegaard, Thomas Skjødeberg

    2010-01-01

    Buildings account for more than a 35 % of the energy consumption in Europe. Therefore a step towards more sustainable lifestile is to use home automation to optimize the energy consumption “automatically”. This paper reports about the usage and some of the remaining challenges of especially...... wireless but also powerline communication in a home automation setting. For many years, home automation has been visible to many, but accessible to only a few, because of inadequate integration of systems. A vast number of both standard and proprietary communication protocols are used, and systems...... are often difficult to install and configure so professional assistance is needed. In this paper we report about our experience in constructing an open universal home automation framework enabling interoperability of multiple communication protocols. The framework can easily be expanded in order to support...

  2. A new principle and device for large aircraft components gaining accurate support by ball joint

    Institute of Scientific and Technical Information of China (English)

    Bao-gui QIU; Jun-xia JIANG; Ying-lin KE

    2011-01-01

    How to obtain an accurate support for large components by ball joint is a key process in aircraft digital assembly. A novel principle and device is developed to solve the problem. Firstly, the working principle of the device is introduced. When three or four displacement sensors installed in the localizer are touched by the ball-head, the spatial relation is calculated between the large aircraft component's ball-head and the localizer's ball-socket. The localizer is driven to achieve a new position by compensation. Relatively, a support revising algorithm is proposed. The localizer's ball-socket approaches the ball-head based on the displacement sensors. According to the points selected from its spherical surface, the coordinates of ball-head spherical center are computed by geometry. Finally, as a typical application, the device is used to conduct a test-fuselage's ball-head into a localizer's ball-socket. Positional deviations of the spherical centers between the ball-head and the ball-socket in the x, y, and z directions are all controlled within ±0.05 mm under various working conditions. The results of the experiments show that the device has the characteristics of high precision, excellent stability, strong operability, and great potential to be applied widely in the modern aircraft industry.

  3. Design of high gain OPCPA for multiterawatt and petawatt class systems on large aperture LBO crystals

    Science.gov (United States)

    Pestryakov, E. V.; Petrov, V. V.; Trunov, V. I.; Frolov, S. A.; Kirpichnikov, A. V.; Bagayev, S. N.; Kokh, A. E.

    2011-02-01

    Comparative analysis of optimal scheme of non-collinear optical chirped-pulse parametric amplification of fewcycle femtosecond pulses from Ti:Sa laser in LBO and DKDP crystals pumped by picosecond pulses up to petawatt level is presented. A flexible code, based on the extended model of parametric amplification, which takes into account the large set of effects such as saturation, phase self-modulation, influence of beam divergence, thermal effects, and amplification of spontaneous emission was realized. A way of creating nearly 1 PW system based on LBO crystals with transform-limited pulse duration about 9 fs has been demonstrated. Comparison between DKDP and LBO crystal showed that the latter is much better for OPCPA petawatt system design than DKDP.

  4. Experience Gained From the Construction, Test and Operation of the Large 4-T CMS Coil

    CERN Document Server

    Hervé, A; Curé, B; Fabbricatore, P; Gaddi, A; Kircher, F; Sgobba, S

    2008-01-01

    The 4-T, 6-m free bore CMS solenoid has been successfully tested, operated and mapped at CERN during the autumn of 2006; R&D studies started in 1993 and the construction proper in 1997. The main parameters of this 100 MUS$ project (including yoke) were then considered beyond what was thought possible, as the total stored magnetic energy reaches 2.6 GJ for a specific magnetic energy density exceeding 11 kJ/kg of cold mass. During this period, the international design and construction team had to make several important technical choices, in particular mechanical, to maximize the chances of reaching the nominal induction of 4 Tesla. The paper will review these choices in the light of what is presently known and examine if better solutions would be possible today for constructing a new large high-field thin solenoid for a future detector magnet.

  5. Wake meandering statistics of a model wind turbine: Insights gained by large eddy simulations

    Science.gov (United States)

    Foti, Daniel; Yang, Xiaolei; Guala, Michele; Sotiropoulos, Fotis

    2016-08-01

    Wind tunnel measurements in the wake of an axial flow miniature wind turbine provide evidence of large-scale motions characteristic of wake meandering [Howard et al., Phys. Fluids 27, 075103 (2015), 10.1063/1.4923334]. A numerical investigation of the wake, using immersed boundary large eddy simulations able to account for all geometrical details of the model wind turbine, is presented here to elucidate the three-dimensional structure of the wake and the mechanisms controlling near and far wake instabilities. Similar to the findings of Kang et al. [Kang et al., J. Fluid Mech. 744, 376 (2014), 10.1017/jfm.2014.82], an energetic coherent helical hub vortex is found to form behind the turbine nacelle, which expands radially outward downstream of the turbine and ultimately interacts with the turbine tip shear layer. Starting from the wake meandering filtering used by Howard et al., a three-dimensional spatiotemporal filtering process is developed to reconstruct a three-dimensional meandering profile in the wake of the turbine. The counterwinding hub vortex undergoes a spiral vortex breakdown and the rotational component of the hub vortex persists downstream, contributing to the rotational direction of the wake meandering. Statistical characteristics of the wake meandering profile, along with triple decomposition of the flow field separating the coherent and incoherent turbulent fluctuations, are used to delineate the near and far wake flow structures and their interactions. In the near wake, the nacelle leads to mostly incoherent turbulence, while in the far wake, turbulent coherent structures, especially the azimuthal velocity component, dominate the flow field.

  6. MANAGEMENT OF LARGE AMELOBLASTOMA: A CASE REPORT

    Directory of Open Access Journals (Sweden)

    Rudagi B M

    2010-03-01

    Full Text Available Ameloblastoma, first recognized by Cusack in 1827, is a neoplasm of odontogenic epithelium, especially of enamel organ-type tissue that has not undergone differentiation to the point of hard tissue formation. It accounts for about 1% of all oral tumors and about 9-11% of odontogenic tumors. Ameloblastoma in the mandible can progress to a great size and cause facial asymmetry, displacement of teeth, malocclusion, and pathologic fractures. A case of large ameloblastoma of mandible in a 39 year old male patient is being reported. Patient had large swelling on left lower side of the jaw since 2 years. Swelling was approximately 15 X 10cm in size. Intraorally the swelling involved buccal and lingual cortical plates and was obliterating the vestibular space. Patient did not seek medical attention because swelling was painless. The patient was investigated and treated with surgical excision and was providedwith prosthesis to correct the post operative sequale. The patient showed uneventful recovery with no recurrence after a follow up of one year.

  7. Large gain for crystalline thin films of thiophene/phenylene co-oligomer by photopumping with femtosecond laser pulses

    Energy Technology Data Exchange (ETDEWEB)

    Mochizuki, Hiroyuki, E-mail: h-mochizuki@aist.go.jp [Electronics and Photonics Research Institutes, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305-8568 (Japan); Kawaguchi, Yoshizo; Sasaki, Fumio [Electronics and Photonics Research Institutes, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305-8568 (Japan); Hotta, Shu [Department of Macromolecular Science and Engineering, Graduate School of Science and Technology, Kyoto Institute of Technology, Kyoto 606-8585 (Japan)

    2014-11-15

    We have evaluated the emission behaviors of crystalline thin films of thiophene/phenylene co-oligomers. Crystalline films of 2,5-bis(4-biphenylyl)thiophene (BP1T) were prepared on a substrate by vapor deposition followed by thermal treatment. The BP1T films contained crystalline domains several hundred micrometers in size. We examined the emission behavior of crystalline BP1T thin films by femtosecond laser excitation. Very high gains of over 500 cm{sup −1} were obtained for the crystalline BP1T film. Furthermore, the emission cross section of the crystalline BP1T film was on the order of 10{sup –16} cm{sup 2}, rivaling that of dilute solutions of organic laser dyes. - Highlights: • Vapor deposition and thermal treatment is effective for preparation of crystallized film. • Femtosecond laser is efficient for excitation of photo-active materials. • Very large gain values over 500 cm{sup −1} for BP1T crystallized films. • Emission cross section of 10{sup −16} cm{sup 2} in crystallized film.

  8. Associations of exercise-induced hormone profiles and gains in strength and hypertrophy in a large cohort after weight training.

    Science.gov (United States)

    West, Daniel W D; Phillips, Stuart M

    2012-07-01

    The purpose of this study was to investigate associations between acute exercise-induced hormone responses and adaptations to high intensity resistance training in a large cohort (n = 56) of young men. Acute post-exercise serum growth hormone (GH), free testosterone (fT), insulin-like growth factor (IGF-1) and cortisol responses were determined following an acute intense leg resistance exercise routine at the midpoint of a 12-week resistance exercise training study. Acute hormonal responses were correlated with gains in lean body mass (LBM), muscle fibre cross-sectional area (CSA) and leg press strength. There were no significant correlations between the exercise-induced elevations (area under the curve-AUC) of GH, fT and IGF-1 and gains in LBM or leg press strength. Significant correlations were found for cortisol, usually assumed to be a hormone indicative of catabolic drive, AUC with change in LBM (r = 0.29, P exercise-induced systemic hormonal responses of cortisol and GH are weakly correlated with resistance training-induced changes in fibre CSA and LBM (cortisol only), but not with changes in strength.

  9. 76 FR 46282 - Gainful Employment Reporting Date for the 2010-2011 Award Year and Continued Collection of...

    Science.gov (United States)

    2011-08-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF EDUCATION Gainful Employment Reporting Date for the 2010-2011 Award Year and Continued Collection of Gainful Employment Information for Prior Award Years AGENCY: Federal Student Aid, Department of Education....

  10. Large spinal intraosseous arteriovenous fistula: case report.

    Science.gov (United States)

    Imajo, Yasuaki; Kanchiku, Tsukasa; Yoshida, Yuichiro; Nishida, Norihiro; Taguchi, Toshihiko

    2015-04-01

    Here the authors report the case of a fresh vertebral body fracture with a large spinal intraosseous arteriovenous fistula (AVF). A 74-year-old woman started to experience low-back pain following a rear-end car collision. Plain radiography showed diffuse idiopathic skeletal hyperostosis (DISH). Sagittal CT sections revealed a transverse fracture of the L-4 vertebral body with a bone defect. Sagittal fat-suppressed T2-weighted MRI revealed a flow void in the fractured vertebra. Spinal angiography revealed an intraosseous AVF with a feeder from the right L-4 segmental artery. A fresh fracture of the L-4 vertebral body with a spinal intraosseous AVF was diagnosed. Observation of a flow void in the vertebral body on fat-suppressed T2-weighted MRI was important for the diagnosis of the spinal intraosseous AVF. Because conservative treatment was ineffective, surgery was undertaken. The day before surgery, embolization through the right L-4 segmental artery was performed using 2 coils to achieve AVF closure. Posterolateral fusion with instrumentation at the T12-S2 vertebral levels was performed without L-4 vertebroplasty. The spinal intraosseous AVF had disappeared after 4 months. At 24 months after surgery, the bone defect was completely replaced by bone and the patient experienced no limitations in daily activities. Given their experience with the present case, the authors believe that performing vertebroplasty or anterior reconstruction may not be necessary in treating spinal intraosseous AVF.

  11. Large prepatellar glomangioma: A case report

    Directory of Open Access Journals (Sweden)

    Melissa L. Maxey

    2015-01-01

    Conclusion: The following case report details an atypical presentation of a benign glomangioma anterior to the knee in a patient experiencing chronic minor trauma to the area. Diagnosis was suggested by clinical presentation and MR imaging, and was confirmed histologically.

  12. The puzzle of self-reported weight gain in a month of fasting (Ramadan among a cohort of Saudi families in Jeddah, Western Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Bakhotmah Balkees

    2011-08-01

    Full Text Available Abstract Background During Ramadan fast, approximately one billion Muslims abstain from food and fluid between the hours of sunrise to sunset, and usually eat a large meal after sunset and another meal before sunrise. Many studies reported good health-related outcomes of fasting including weight loss. The objective of this study is to identify the local pattern of expenditure on food consumption, dietary habits during Ramadan and correlate that to self-reported weight gain after Ramadan in a group of families in Jeddah, Western Saudi Arabia. Methods A Cross-section study using a pre-designed questionnaire to identify the local pattern of expenditure on food consumption, dietary habits during Ramadan and correlate that to self-reported weight gain after Ramadan in a representative cohort of Saudis living in Jeddah. It was piloted on 173 nutrition students and administered by them to their families. Results A total of 173 Saudi families were interviewed. One out of 5 indicated that their expenditure increases during Ramadan. Approximately two thirds of the respondents (59.5% reported weight gain after Ramadan. When asked about their perspective explanations for that: 40% attributed that to types of foods being rich in fat and carbohydrates particularly date in (Sunset meal 97.7% and rice in (Dawn meal 80.9%. One third (31.2% indicated that it was due to relative lack of physical exercise in Ramadan and 14.5% referred that to increase in food consumption. Two thirds (65.2% of those with increased expenditure reported weight gain. Conclusion Surprisingly weight gain and not weight loss was reported after Ramadan by Saudis which indicates timely needed life-style and dietary modification programs for a population which reports one of the highest prevalence rates of diabetes.

  13. The Impact of Waiting Time on Health Gains from Surgery: Evidence from a National Patient-reported Outcome Dataset.

    Science.gov (United States)

    Nikolova, Silviya; Harrison, Mark; Sutton, Matt

    2016-08-01

    Reducing waiting times has been a major focus of the English National Health Service for many years, but little is known about the impact on health outcomes. The collection of data on patient-reported outcome measures for all patients undergoing four large-volume procedures facilitates analysis of the impact of waiting times on patient outcomes. The availability of patient-reported outcome measures before and after surgery allows us to estimate the impact of waiting times on the effectiveness of treatment, controlling for pre-surgery health and the endogeneity of waiting times caused by prioritisation with respect to pre-intervention health. We find that waiting time has a negative and statistically significant impact on the health gain from hip and knee replacement surgery and no impact on the effectiveness of varicose vein and hernia surgery. The magnitude of this effect at patient level is small, 0.1% of the outcome measure range for each additional week of waiting. However, the value of this effect is substantially larger than existing estimates of the disutility experienced during the waiting period. The health losses associated with an additional week of waiting for annual populations of hip and knee replacement patients are worth £11.1m and £11.5m, respectively. Copyright © 2015 John Wiley & Sons, Ltd.

  14. Massachusetts Large Blade Test Facility Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Rahul Yarala; Rob Priore

    2011-09-02

    Project Objective: The Massachusetts Clean Energy Center (CEC) will design, construct, and ultimately have responsibility for the operation of the Large Wind Turbine Blade Test Facility, which is an advanced blade testing facility capable of testing wind turbine blades up to at least 90 meters in length on three test stands. Background: Wind turbine blade testing is required to meet international design standards, and is a critical factor in maintaining high levels of reliability and mitigating the technical and financial risk of deploying massproduced wind turbine models. Testing is also needed to identify specific blade design issues that may contribute to reduced wind turbine reliability and performance. Testing is also required to optimize aerodynamics, structural performance, encourage new technologies and materials development making wind even more competitive. The objective of this project is to accelerate the design and construction of a large wind blade testing facility capable of testing blades with minimum queue times at a reasonable cost. This testing facility will encourage and provide the opportunity for the U.S wind industry to conduct more rigorous testing of blades to improve wind turbine reliability.

  15. Association Between Gestational Weight Gain According to Body Mass Index and Postpartum Weight in a Large Cohort of Danish Women

    DEFF Research Database (Denmark)

    Rode, Line; Kjærgaard, Hanne; Ottesen, Bent

    2012-01-01

    Our aim was to investigate the association between gestational weight gain (GWG) and postpartum weight retention (PWR) in pre-pregnancy underweight, normal weight, overweight or obese women, with emphasis on the American Institute of Medicine (IOM) recommendations. We performed secondary analyses...... on data based on questionnaires from 1,898 women from the "Smoke-free Newborn Study" conducted 1996-1999 at Hvidovre Hospital, Denmark. Relationship between GWG and PWR was examined according to BMI as a continuous variable and in four groups. Association between PWR and GWG according to IOM...... weight, 60% of overweight and 50% of obese women gained more than recommended during pregnancy. For normal weight and overweight women with GWG above recommendations the OR of gaining = 5 kg (11 lbs) 1-year postpartum was 2.8 (95% CI 2.0-4.0) and 2.8 (95% CI 1.3-6.2, respectively) compared to women...

  16. Low Birthweight, Rapid Weight Gain and Metabolic Syndrome in Adolescence: An Illustrative Case Report

    Directory of Open Access Journals (Sweden)

    Onyiriuka Alphonsus N.

    2015-12-01

    Full Text Available A 16-year-old boy whose diabetes mellitus was diagnosed 3 months previously in a private hospital but was not placed on medication. The presenting complaints were fast breathing for 24 hours, weakness for 2 hours, and unresponsiveness to calls for 0.5 hours. His father was obese with type 2 diabetes mellitus and died 8 months earlier from cardiac arrest. His birthweight was low, 2.2kg. At first presentation, his weight, BMI and blood pressure were 60kg (25th-50th percentile, 19.4kg/m2 (25thpercentile and 110/70mmHg (systolic BP 50th percentile, diastolic BP 50th-90th percentile, respectively. He was managed for diabetic ketoacidosis and was discharged on subcutaneous premixed insulin, 1 Unit/kg/day. At point of discharge, weight and BP were 60.5 kg and 120/70 mmHg, respectively. The patient defaulted but presented again 6 months later at the age of 17 years. At second presentation, his weight, BMI and BP were 89 kg (95th percentile, 27.5 kg/m2 (90th-95th percentile and 180/80 mmHg (systolic 99th percentile; diastolic 90th percentile, respectively. His waist circumference was 98.7cm (> 90th percentile. We had no record of previous waist circumference. His lipid profile showed low HDL-cholesterol 0.7252 mmol/L [(28mg/dl; <5thpercentile]. His fasting blood glucose and HbA1C were 6.5 mmol/L (117mg/dl and 34 mol/mol (5.3%, respectively. A diagnosis of metabolic syndrome in a patient with ketosis-prone type 2 diabetes was made. He was referred to the pediatric cardiologist for management of his hypertension. He defaulted again and was lost to follow up. Conclusion: This report illustrates the association of low birth weight and rapid weight gain with metabolic syndrome in adolescence.

  17. Excessive weight gain after remission of depression in a schizophrenic patient treated with risperidone: case report

    Directory of Open Access Journals (Sweden)

    Psarros Constantin

    2006-09-01

    Full Text Available Abstract Background The use of atypical antipsychotics in schizophrenic patients has been associated with a risk of weight gain. Similarly, recovery from depression is often followed by improved appetite, greater food intake and potential increase in weight. Case presentation A Caucasian 33-year-old schizophrenic female patient was being treated with 6 mg/day of risperidone and 15 mg/day of clorazepate. She developed depressive symptomatology and 40 mg/day of fluoxetine was gradually added to her treatment regimen for about 9 months. After the remission of depression, and the discontinuation of fluoxetine, she experienced an increase in appetite and subsequently excessive weight gain of 52 kg. Re-administration of fluoxetine did not reverse the situation. The patient developed diabetes mellitus, which was successfully controlled with metformin 1700 mg/day. The addition at first of orlistat 360 mg/day and later of topiramate 200 mg/day has helped her to lose a significant part of the weight gained (30 kg. Conclusion The case suggests a probable association between the remission of depressive symptomatology and weight gain in a schizophrenic patient.

  18. 77 FR 12646 - Government Securities: Call for Large Position Reports

    Science.gov (United States)

    2012-03-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Government Securities: Call for Large Position Reports AGENCY: Office of the Assistant Secretary for... ``Treasury'') called for the submission of Large Position Reports by those entities whose...

  19. 78 FR 17469 - Government Securities: Call for Large Position Reports

    Science.gov (United States)

    2013-03-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Government Securities: Call for Large Position Reports AGENCY: Office of the Assistant Secretary for... ``Treasury'') called for the submission of Large Position Reports by those entities whose...

  20. 75 FR 77955 - Government Securities: Call for Large Position Reports

    Science.gov (United States)

    2010-12-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Government Securities: Call for Large Position Reports AGENCY: Office of the Assistant Secretary for... ``Treasury'') called for the submission of Large Position Reports by those entities whose...

  1. A gain regulation system for a large set of photomultipliers using light-emitting diodes and optical filters

    CERN Document Server

    De Palma, M; Sacchetti, A; Spirelli, P; Waldner, F

    1979-01-01

    Describes the solution adopted for the on-line gain regulation with a PDP 11/60 of the 480 photomultipliers of the calorimeter of the experiment NA5 (at CERN) by means of light emitting diodes (LEDs) and polymer optical fibers. The regulation of the light yield of the LEDs is obtained comparing it to the light pulse of a NaI scintillator doped with /sup 241/Am. (6 refs).

  2. Complications of fat grafts growth after weight gain: report of a severe diplopia.

    Science.gov (United States)

    Duhoux, Alexandre; Chennoufi, Mehdi; Lantieri, Laurent; Hivelin, Mikael

    2013-07-01

    A 47 years old woman underwent autologous fat grafting to treat a 5×4 cm depression of the lower lid and the upper cheek secondary resection of squamous cell carcinoma and subsequent coverage by full thickness skin graft. 20 mL of autologous fat were harvested from lower abdomen, centrifuged and injected subcutaneously. The patient then gained a total of 15 kg over a period of 24 months. Eye dystopia developed while the grafted area became convex. MRI confirmed subcutaneous fat mass going to the orbital floor through the inferior septal defect. The fat excess was removed through a trans-conjonctival approach allowing for a progressive regression of diplopia after 2 months while the oedema reduced. The overall follow up from the resection-coverage and last examination was 5 years. In this case with a context of noticeable weight gain, the growth of a fat graft trapped between a sclerous plane and the eye, that penetrated the orbital cavity through a septal defect led have led to exophthalmos, ocular dystopia and diplopia. Systematic overcorrection in autologous fat grafting should be prevented, especially in functional areas and on low body mass index patient that might gain weight.

  3. Olanzapine-high potency antipsychotic drug inducing significant weight gain: A case report

    Directory of Open Access Journals (Sweden)

    Marić Nađa P.

    2008-01-01

    Full Text Available INTRODUCTION Olanzapine is a second generation antipsychotic (SGA with a high level of therapeutic effectiveness in schizophrenia and other psychotic disorders. Along with the positive therapeutic effects, an increase of the body weight frequently occurs. According to the literature, the average weight gain is about 6-7 kg during several months of treatment. This could be valued as a moderate weight increase. CASE OUTLINE This article presents a case of a young female with schizophrenia, without clinical improvement with several antipsychotics (clozapine, risperidone, haloperidol and with the occurrence of significant neurological side effects. The treatment started with olanzapine (baseline was associated with good initial response (PANSS reduction 20% in the first two weeks and the improvement was maintained further on (PANSS reduction 50% after 16 weeks. Significant increase (20 kg, 40% in weight appeared during the following 16 weeks (BMI at baseline 17.9 kg/m2; BMI 16 weeks later 25.1 kg/m2. CONCLUSION High effectiveness of olanzapine in schizophrenia symptoms reduction was accompanied by a significant weight gain. However, this drug leads to impaired glucoregulation, dyslipidaemia etc. It also increases the risk of diabetes and cardio-vascular diseases, i.e. the main causes of mortality in schizophrenia after a suicide. Therefore, clinicians are suggested to focus on possible predictors of weight gain during olanzapine therapy, and act accordingly in order to prevent serious health consequences.

  4. Large-scale phylogenetic analyses reveal multiple gains of actinorhizal nitrogen-fixing symbioses in angiosperms associated with climate change.

    Science.gov (United States)

    Li, Hong-Lei; Wang, Wei; Mortimer, Peter E; Li, Rui-Qi; Li, De-Zhu; Hyde, Kevin D; Xu, Jian-Chu; Soltis, Douglas E; Chen, Zhi-Duan

    2015-09-10

    Nitrogen is fundamental to all life forms and is also one of the most limiting of nutrients for plant growth. Several clades of angiosperms have developed symbiotic relationships with actinorhizal bacteria that fix atmospheric nitrogen and increase access to this nutrient. However, the evolutionary patterns of actinorhizal nitrogen-fixing symbioses remain unclear to date. Furthermore the underlying environmental pressures that led to the gain of symbiotic actinorhizal nitrogen fixation have never been investigated. Here, we present the most comprehensive genus-level phylogenetic analysis of the nitrogen-fixing angiosperms based on three plastid loci. We found that actinorhizal nitrogen-fixing species are distributed in nine distinct lineages. By dating the branching events, we determined that seven actinorhizal nitrogen-fixing lineages originated during the Late Cretaceous, and two more emerged during the Eocene. We put forward a hypothesis that multiple gains of actinorhizal nitrogen-fixing symbioses in angiosperms may have been associated with increased global temperatures and high levels of atmospheric carbon dioxide during these two time periods, as well as the availability of open habitats with high light conditions. Our nearly complete genus-level time-tree for the nitrogen-fixing clade is a significant advance in understanding the evolutionary and ecological background of this important symbiosis between plants and bacteria.

  5. Gain and Polarization Properties of a Large Radio Telescope from Calculation and Measurement: The John A. Galt Telescope

    CERN Document Server

    Du, Xuan; Robishaw, Timothy; Gray, Andrew D; Douglas, Kevin A; Wolleben, Maik

    2016-01-01

    Measurement of the brightness temperature of extended radio emission demands knowledge of the gain (or aperture efficiency) of the telescope and measurement of the polarized component of the emission requires correction for the conversion of unpolarized emission from sky and ground to apparently polarized signal. Radiation properties of the John A. Galt Telescope at the Dominion Radio Astrophysical Observatory were studied through analysis and measurement in order to provide absolute calibration of a survey of polarized emission from the entire northern sky from 1280 to 1750 MHz, and to understand the polarization performance of the telescope. Electromagnetic simulators CST and GRASP-10 were used to compute radiation patterns of the telescope in all Stokes parameters, and aperture efficiency. Aperture efficiency was also evaluated using geometrical optics and was measured using Cyg A. Measured aperture efficiency varied smoothly with frequency between values of 0.49 and 0.54; GRASP-10 yielded values 6.5% high...

  6. Purulent Pericarditis Caused by Streptococcus Milleri Strains; the Gained Experience from Nine Reported Cases

    Directory of Open Access Journals (Sweden)

    Ilias A. Kouerinis

    2015-12-01

    Full Text Available Bacterial pericarditis caused by Streptococcus Milleri Group (SMG strains is a particularly exceptional pathology. All the eight previous reported cases were under the care of medical teams and the seven existed reports in medical journals were more or less from this perspective. Herein, we reported a unique case of a pericardial-cutaneous fistula resulting from a recurrent purulent pericardial effusion caused by SMG strains, which had been treated with open surgical drainage two months before. A thorough review of the surgical treatment options and the results has also been presented.

  7. Senior nursing students' self-reported college experiences and gains toward liberal education goals.

    Science.gov (United States)

    Zaborowska, R

    1995-04-01

    The purpose of this descriptive study is to assess baccalaureate nursing students' self-reported achievements toward liberal education goals in college and university settings and compare them to norms for the general college population by measuring their perceived involvement in campus life and activities. At the end of the spring semester, senior nursing students from 11 nursing programs in the Midwest filled out the College Student Experience Questionnaire, developed by Pace (1984), which measures the effort students put into liberal education goals. Nursing students reported high involvement in academic activities, but little involvement in other types of experiences in the college; they reported significant progress toward academic goals like intellectual skills, but less progress toward liberal education goals like art, literature, and music. Nursing students were very similar to other college students (except for students in selective liberal arts colleges) in reported involvement in activities and made similar progress toward liberal education goals.

  8. Unusually large erupted complex odontoma: A rare case report

    Energy Technology Data Exchange (ETDEWEB)

    Bagewadi, Shivanand B.; Kukreja, Rahul; Suma, Gundareddy N.; Yadav, Bhawn; Sharma, Havi [Dept. of Oral Medicine and Radiology, ITS Centre for Dental Studies and Research, Murad Nagar (India)

    2015-03-15

    Odontomas are nonaggressive, hamartomatous developmental malformations composed of mature tooth substances and may be compound or complex depending on the extent of morphodifferentiation or on their resemblance to normal teeth. Among them, complex odontomas are relatively rare tumors. They are usually asymptomatic in nature. Occasionally, these tumors become large, causing bone expansion followed by facial asymmetry. Odontoma eruptions are uncommon, and thus far, very few cases of erupted complex odontomas have been reported in the literature. Here, we report the case of an unusually large, painless, complex odontoma located in the right posterior mandible.

  9. Unusually large erupted complex odontoma: A rare case report.

    Science.gov (United States)

    Bagewadi, Shivanand B; Kukreja, Rahul; Suma, Gundareddy N; Yadav, Bhawna; Sharma, Havi

    2015-03-01

    Odontomas are nonaggressive, hamartomatous developmental malformations composed of mature tooth substances and may be compound or complex depending on the extent of morphodifferentiation or on their resemblance to normal teeth. Among them, complex odontomas are relatively rare tumors. They are usually asymptomatic in nature. Occasionally, these tumors become large, causing bone expansion followed by facial asymmetry. Odontoma eruptions are uncommon, and thus far, very few cases of erupted complex odontomas have been reported in the literature. Here, we report the case of an unusually large, painless, complex odontoma located in the right posterior mandible.

  10. 105-DR Large Sodium Fire Facility closure activities evaluation report

    Energy Technology Data Exchange (ETDEWEB)

    Adler, J.G.

    1996-04-22

    This report evaluates the closure activities at the 105-DR Large Sodium Fire Facility. The closure activities discussed include: the closure activities for the structures, equipment, soil, and gravel scrubber; decontamination methods; materials made available for recycling or reuse; and waste management. The evaluation compares these activities to the regulatory requirements and closure plan requirements. The report concludes that the areas identified in the closure plan can be clean closed.

  11. Polymorphisms in FTO and MAF Genes and Birth Weight, BMI, Ponderal Index, Weight Gain in a Large Cohort of Infants with a Birth Weight below 1500 Grams.

    Directory of Open Access Journals (Sweden)

    Sebastian Haller

    Full Text Available The FTO gene, located on chromosome 16q12.2, and the MAF gene, located on chromosome 16q22-23, were identified as genes harboring common variants with an impact on obesity predisposition. We studied the association of common variants with birth weight, gain of body weight, body mass index (BMI, Ponderal index and relevant neonatal outcomes in a large German cohort of infants with a birth weight below 1500 grams.The single nucleotide polymorphisms rs9939609 (FTO gene and rs1424233 (MAF gene were genotyped using allelic discrimination assays in a prospective multicenter cohort study conducted in 15 neonatal intensive care units in Germany from September 2003 until January 2008. DNA samples were extracted from buccal swabs according to standard protocols.1946 infants were successfully genotyped at FTO and 2149 infants at MAF. Allele frequencies were not significantly different from other European cohorts. The polymorphisms were in Hardy-Weinberg equilibrium. The polymorphisms did not show associations with birth weight, BMI and Ponderal Index at discharge, and weight gain, neither testing for a dominant, additive nor for a recessive model.Since an association of the polymorphisms with weight gain has been demonstrated in multiple populations, the lack of association in a population of preterm infants with regular tube feeding after birth and highly controlled feeding volumes provides evidence for the hypothesis that these polymorphisms affect food intake behavior and hunger rather than metabolism and energy consumption.

  12. Resection of a large ectopic parathyroid adenoma: A case report

    Directory of Open Access Journals (Sweden)

    Seijiro Sato

    2016-01-01

    Discussion and conclusions: Parathyroid adenomas and parathyroid carcinomas have disparate natural histories, but they can be difficult to differentiate on the basis of preoperative clinical characteristics. We believe that long-term follow-up of these cases is required because there have been few reports on the postoperative natural history of large parathyroid adenomas.

  13. Ichthyosiform Large Plaque Parapsoriasis: Report of a Rare Entity

    OpenAIRE

    Falguni Nag; Arghyaprasun Ghosh; Projna Biswas; Gobinda Chatterjee; Saugato Biswas

    2013-01-01

    Large plaque parapsoriasis (LPP) is an idiopathic, chronic scaly dermatosis classified within parapsoriasis group of diseases, occurring commonly in middle aged patients of all races and geographic regions. LPP and its variants are closely related to the patch stage of mycosis fungoides. The two types of LPP mostly described are the poikilodermatous and retiform parapsoriasis. We are reporting an ichthyosiform LPP for its rarity.

  14. Ichthyosiform large plaque parapsoriasis: report of a rare entity.

    Science.gov (United States)

    Nag, Falguni; Ghosh, Arghyaprasun; Biswas, Projna; Chatterjee, Gobinda; Biswas, Saugato

    2013-09-01

    Large plaque parapsoriasis (LPP) is an idiopathic, chronic scaly dermatosis classified within parapsoriasis group of diseases, occurring commonly in middle aged patients of all races and geographic regions. LPP and its variants are closely related to the patch stage of mycosis fungoides. The two types of LPP mostly described are the poikilodermatous and retiform parapsoriasis. We are reporting an ichthyosiform LPP for its rarity.

  15. Large oral lipoma: Case report and literature review in Iran

    Directory of Open Access Journals (Sweden)

    Ahmad Motagi

    2012-01-01

    Full Text Available Lipoma is a benign mesenchymal tumor of fat with uncertain pathogenesis. Although the most common mesenchymal neoplasm in trunk and proximal portions of the extremities, it is rarely seen in the oral cavity. Oral lipomas are clinically soft, smooth-surfaced nodular masses that mostly are less than 3 cm in size. Typically the tumor is asymptomatic unless bitten or become noticeable because of their size. The buccal mucosa and buccal vestibule are the most common intraoral sites and account for 50% of all cases. Reported here is a relatively large lipoma of buccal mucosa that was treated surgically under local anesthesia. In an 18-month postsurgical follow up no complication or recurrence has occurred. This case will also be compared to intraoral lipomas reported in Iranian population. As lipomas are usually smaller than 3 cm in diameter, lipoma with the size reported, is of clinical importance. Since the large lipomas are in differential diagnosis with other, even malignant, mesenchymal, or salivary gland tumors. Thus, this case report recommends clinical awareness in diagnosis of large intraoral soft tissue lesions.

  16. Report from the 4th Workshop on Extremely Large Databases

    Directory of Open Access Journals (Sweden)

    Jacek Becla

    2011-02-01

    Full Text Available Academic and industrial users are increasingly facing the challenge of petabytes of data, but managing and analyzing such large data sets still remains a daunting task. The 4th Extremely Large Databases workshop was organized to examine the needs of communities under-represented at the past workshops facing these issues. Approaches to big data statistical analytics as well as emerging opportunities related to emerging hardware technologies were also debated. Writable extreme scale databases and the science benchmark were discussed. This paper is the final report of the discussions and activities at this workshop.

  17. Report from the 2nd Workshop on Extremely Large Databases

    Directory of Open Access Journals (Sweden)

    Jacek Becla

    2009-03-01

    Full Text Available The complexity and sophistication of large scale analytics in science and industry have advanced dramatically in recent years. Analysts are struggling to use complex techniques such as time series analysis and classification algorithms because their familiar, powerful tools are not scalable and cannot effectively use scalable database systems. The 2nd Extremely Large Databases (XLDB workshop was organized to understand these issues, examine their implications, and brainstorm possible solutions. The design of a new open source science database, SciDB that emerged from the first workshop in this series was also debated. This paper is the final report of the discussions and activities at this workshop.

  18. Umbilical endometriosis associated with large umbilical hernia. Case report.

    Science.gov (United States)

    Stojanovic, M; Radojkovic, M; Jeremic, L; Zlatic, A; Stanojevic, G; Janjic, D; Mihajlovic, S; Dimov, I; Kostov, M; Zdravkovic, M; Stojanovic, M

    2014-01-01

    Umbilical endometriosis is a rare condition, usually following laparoscopic and surgical procedures involving the umbilicus.Spontaneous umbilical endometriosis occurring without any previous abdominal or uterine surgery is extremely rare. The maximal depth of penetration of the umbilical endometriosis described is up to fascial level. There have been only two cases of endometriosis reported arising within umbilical hernia. The authors report a case of a patient with spontaneous umbilical endometriosis associated with a large umbilical hernia, treated by surgical excision and mesh repair of the abdominal wall. To the best of our knowledge, this is the first described case of the association of umbilical endometriosis with a large umbilical hernia that requires prosthetic mesh repair of the abdominal wall defect.

  19. Report from the 3rd Workshop on Extremely Large Databases

    Directory of Open Access Journals (Sweden)

    Jacek Becla

    2010-02-01

    Full Text Available Academic and industrial users are increasingly facing the challenge of petabytes of data, but managing and analyzing such large data sets still remains a daunting task. Both the database and the map/reduce communities worldwide are working on addressing these issues. The 3rdExtremely Large Databases workshop was organized to examine the needs of scientific communities beginning to face these issues, to reach out to European communities working on extremely large scale data challenges, and to brainstorm possible solutions. The science benchmark that emerged from the 2nd workshop in this series was also debated. This paper is the final report of the discussions and activities at this workshop.

  20. Ichthyosiform large plaque parapsoriasis: Report of a rare entity

    Directory of Open Access Journals (Sweden)

    Falguni Nag

    2013-01-01

    Full Text Available Large plaque parapsoriasis (LPP is an idiopathic, chronic scaly dermatosis classified within parapsoriasis group of diseases, occurring commonly in middle aged patients of all races and geographic regions. LPP and its variants are closely related to the patch stage of mycosis fungoides. The two types of LPP mostly described are the poikilodermatous and retiform parapsoriasis. We are reporting an ichthyosiform LPP for its rarity.

  1. OVERSMART Reporting Tool for Flow Computations Over Large Grid Systems

    Science.gov (United States)

    Kao, David L.; Chan, William M.

    2012-01-01

    Structured grid solvers such as NASA's OVERFLOW compressible Navier-Stokes flow solver can generate large data files that contain convergence histories for flow equation residuals, turbulence model equation residuals, component forces and moments, and component relative motion dynamics variables. Most of today's large-scale problems can extend to hundreds of grids, and over 100 million grid points. However, due to the lack of efficient tools, only a small fraction of information contained in these files is analyzed. OVERSMART (OVERFLOW Solution Monitoring And Reporting Tool) provides a comprehensive report of solution convergence of flow computations over large, complex grid systems. It produces a one-page executive summary of the behavior of flow equation residuals, turbulence model equation residuals, and component forces and moments. Under the automatic option, a matrix of commonly viewed plots such as residual histograms, composite residuals, sub-iteration bar graphs, and component forces and moments is automatically generated. Specific plots required by the user can also be prescribed via a command file or a graphical user interface. Output is directed to the user s computer screen and/or to an html file for archival purposes. The current implementation has been targeted for the OVERFLOW flow solver, which is used to obtain a flow solution on structured overset grids. The OVERSMART framework allows easy extension to other flow solvers.

  2. Large solitary retroperitoneal echinococcal cyst: A rare case report

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Echinococcal disease remains a problem within some endemic areas. Echinococcal cysts usually involve the liver and lungs,but any other organ can potentially be involved.Extrahepatic localization is reported in14%-19% of all cases of abdominal hydatid disease. We report the case of a large echinococcal cyst localized in the lower pelvis. A 28-year-old woman was admitted to a surgical ward with lower abdominal pain and discomfort lasting for a month. Ultrasonography and computed tomography scanning revealed a large retroperitoneal cystic mass (9 cm×4 cm) in contact with the left ovary and leftureter. There were no cysts in any other location.Serological tests were positive for Echinococcus. The patient was operated on and the entire cyst was excised intact. Histopathological results confirmed the diagnosis of chinococcosis.ntihelminthics were administered postoperatively and the patient was discharged after 6 d,and is now being closely followed up. Total cystectomy when possible represents the treatment of choice for large extrahepatic echinococcal cysts.

  3. Chronic tophaceous gout with unusual large tophi: case report

    Science.gov (United States)

    Aradoini, Nassira; Talbi, Sofia; Berrada, Khadija; Abourazzak, Fatima Zahra; Harzy, Taoufik

    2015-01-01

    Gout is a metabolic disease, which is characterized by acute or chronic arthritis, and deposition of monosodium urate crystals in joint, bones, soft tissues, and kidneys. But large tophi are unusual in chronic gout. We report the case of a 67-year-oldArabman presenting chronic tophaceous gout with unusual large tophi involving multiple joints: hands, feet, elbows, and knees. Laboratory workup revealed elevated serum uric acid (96 mg/l, normal: 20-74 mg/l), with normal renal function test. In untreated patients, chronic tophaceous gout may develop, which is characterized by chronic destructive polyarticular involvement and tophi. The treatment consists to decrease serum uric acid level which eventually allows the regression of tophi. PMID:26889313

  4. Large pericardial cyst in an asymptomatic child: a case report.

    Science.gov (United States)

    Loggos, S; Mitropoulos, F; Kondrafouris, K; Milonakis, M; Kanakis, M; Chantzis, A; Bobos, D; Giannopoulos, N; Azariadis, P

    2013-07-01

    We present a case report of a nine-year-old asymptomatic girl with a large cystic lesion of the left hemithorax, occupying almost 80% of the left hemithorax, first believed to be a parasitic cyst that was operated and proved to be of parietal pericardial origin. Mediastinal cysts and pericardial cysts in particular are mostly discovered accidentally and so was the case with our patient. The diagnosis included not only clinical examination but also the utilization of computed tomography and magnetic resonance imaging. The only treatment for pericardial cysts is surgical excision and patients recover fully with no complication.

  5. Dual anaplastic large cell lymphoma mimicking meningioma: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Keun Ho; Kim, Ki Hwan; Lee, Ghi Jai; Lee, Hye Kyung; Shim, Jae Chan; Lee, Kyoung Eun; Suh, Jung Ho [Seoul Paik Hospital, Inje University College of Medicine, Seoul (Korea, Republic of); Lee, Chae Heuck [Dept. of Neurosurgery, Ilsan Paik Hospital, Inje University College of Medicine, Goyang (Korea, Republic of)

    2014-01-01

    Anaplastic large cell lymphoma (ALCL) is a rare T cell lymphoma composed of CD30-positive lymphoid cells. Most ALCLs present as nodal disease, with skin, bone, soft tissue, lung, and liver as common extranodal sites. ALCL rarely occurs in the central nervous system and is even more infrequent in the dura of the brain. We report a case of dural-based ALCL secondary to systemic disease in a 17-year-old male that mimicked meningioma on magnetic resonance imaging and angiography.

  6. Large Lipoma of the Larynx: A Case Report

    Directory of Open Access Journals (Sweden)

    Mohammad Taghi Khorsandi Ashtiani

    2010-10-01

    Full Text Available Fewer than 15% of lipomas occur in the head and neck. Lipomas of the larynx are very rare benign laryngeal tumors (0.6%. To date less than 100 case of laryngeal lipoma have been reported in the literature.Clinical manifestation include progressive horseness, dyspnea, and even dysphagia. In the direct exam smooth or pedunculated mass is seen in the larynx and sometimes if tumor is large enough a mass palpated in the neck. In the computed tomography (CT low attenuation mass is seen. Treatment of laryngeal lipoma consists of endoscopic removal or external surgical approach depending on tumor size. The authors present a case of laryngeal lipoma that involved the true vocal cord. The following is a report of a single case of laryngeal lipoma, Including esteroboscopy, radiologic and intraoperative finding as well as review of the literature.

  7. Case report: rheumatoid arthritis and large granular lymphocytes syndrome

    Directory of Open Access Journals (Sweden)

    P. Bonara

    2011-09-01

    Full Text Available Felty’s syndrome (FS is a rare complication (less than 1% of rheumatoid arthritis (RA, with the clinical feature of splenomegaly and neutropenia. Approximately 10-40% of FS patients have an expansion of peripheral blood large granular lymphocytes (LGL. This cell population mainly consists of two subsets: cytotoxic T cells (CD8+, CD57+ and natural killer cells (CD3-,CD8-,CD56+. It has been hypothesised that LGL expansion could be responsible for neutropenia by suppressing neutrophil precursors in the bone marrow, but various mechanisms have been proposed to explain this association. We report a case of a 60-year-old woman with rheumatoid factor positive RA who developed LGL expansion responsible for splenomegaly, but without neutropenia. In conclusion, LGL expansion is an uncommon complication of RA and may be responsible for both FS and clinical pictures resembling FS.

  8. Update in large cell lymphoma: understanding the pathology report.

    Science.gov (United States)

    Hsi, Eric D

    2015-01-01

    The diffuse aggressive large B-cell lymphomas are a heterogeneous group of B-cell malignancies. Although many are readily recognized due to characteristic clinical and pathologic features, several problematic areas still exist in diagnosis of these lymphomas due to a variety of reasons that include imprecise or difficult-to-apply diagnostic criteria, gaps in our understanding of lymphoma biology, and limitations in technologies available in the clinical laboratory compared to the research laboratory. This may result in some degree of confusion in the pathology report, particularly if the issues are not clearly explained, leading to frustration or misinterpretation on the part of the reader. In this review, I will discuss the pathologic features of a subset of the WHO 2008 classification diffuse aggressive large B-cell lymphomas, focusing on areas in which difficulties exist in diagnosis and/or biomarker marker assessment. A deeper understanding of the issues and areas of uncertainty due to limitations in our knowledge about the biology of these diseases should lead to better communication between pathologists and clinicians.

  9. Large scale photovoltaic field trials. Second technical report: monitoring phase

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-09-15

    This report provides an update on the Large-Scale Building Integrated Photovoltaic Field Trials (LS-BIPV FT) programme commissioned by the Department of Trade and Industry (Department for Business, Enterprise and Industry; BERR). It provides detailed profiles of the 12 projects making up this programme, which is part of the UK programme on photovoltaics and has run in parallel with the Domestic Field Trial. These field trials aim to record the experience and use the lessons learnt to raise awareness of, and confidence in, the technology and increase UK capabilities. The projects involved: the visitor centre at the Gaia Energy Centre in Cornwall; a community church hall in London; council offices in West Oxfordshire; a sports science centre at Gloucester University; the visitor centre at Cotswold Water Park; the headquarters of the Insolvency Service; a Welsh Development Agency building; an athletics centre in Birmingham; a research facility at the University of East Anglia; a primary school in Belfast; and Barnstable civic centre in Devon. The report describes the aims of the field trials, monitoring issues, performance, observations and trends, lessons learnt and the results of occupancy surveys.

  10. Cutaneous Metastasis of Large Cell Lung Cancer: A Case Report

    Directory of Open Access Journals (Sweden)

    Ižsmail Gedik

    2016-05-01

    Full Text Available Lung cancer has the highest incidence among all cancer types in the world. Skin is an uncommon organ that lung cancers metastasize and the incidence of cutaneous metastasis has been reported between 1-12%. In this report, we would like to present the case of a 67 year old male patient who admitted to our hospital with the complaint of multiple swollen masses on the different parts of his skin and has a homogenous mass with the width of 3 cm on chest x ray. The nodule at the intersection of the right 6th intercostal space and the mid-axillary line and with the dimensions of 1.5x1 cm was excised under local anesthesia and the specimen was sent to the pathology laboratory for histopathological examination. The diagnosis of %u201Clarge cell neuroendocrine carcinoma%u201D was made histopathologically. The patient was diagnosed as the distant metastasis of the large cell lung cancer, considered inoperable and referred to oncology clinics.

  11. Sub-megabase resolution tiling (SMRT array-based comparative genomic hybridization profiling reveals novel gains and losses of chromosomal regions in Hodgkin Lymphoma and Anaplastic Large Cell Lymphoma cell lines

    Directory of Open Access Journals (Sweden)

    Lam Wan L

    2008-01-01

    Full Text Available Abstract Background Hodgkin lymphoma (HL and Anaplastic Large Cell Lymphoma (ALCL, are forms of malignant lymphoma defined by unique morphologic, immunophenotypic, genotypic, and clinical characteristics, but both overexpress CD30. We used sub-megabase resolution tiling (SMRT array-based comparative genomic hybridization to screen HL-derived cell lines (KMH2 and L428 and ALCL cell lines (DEL and SR-786 in order to identify disease-associated gene copy number gains and losses. Results Significant copy number gains and losses were observed on several chromosomes in all four cell lines. Assessment of copy number alterations with 26,819 DNA segments identified an average of 20 genetic alterations. Of the recurrent minimally altered regions identified, 11 (55% were within previously published regions of chromosomal alterations in HL and ALCL cell lines while 9 (45% were novel alterations not previously reported. HL cell lines L428 and KMH2 shared gains in chromosome cytobands 2q23.1-q24.2, 7q32.2-q36.3, 9p21.3-p13.3, 12q13.13-q14.1, and losses in 13q12.13-q12.3, and 18q21.32-q23. ALCL cell lines SR-786 and DEL, showed gains in cytobands 5p15.32-p14.3, 20p12.3-q13.11, and 20q13.2-q13.32. Both pairs of HL and ALCL cell lines showed losses in 18q21.32-18q23. Conclusion This study is considered to be the first one describing HL and ALCL cell line genomes at sub-megabase resolution. This high-resolution analysis allowed us to propose novel candidate target genes that could potentially contribute to the pathogenesis of HL and ALCL. FISH was used to confirm the amplification of all three isoforms of the trypsin gene (PRSS1/PRSS2/PRSS3 in KMH2 and L428 (HL and DEL (ALCL cell lines. These are novel findings that have not been previously reported in the lymphoma literature, and opens up an entirely new area of research that has not been previously associated with lymphoma biology. The findings raise interesting possibilities about the role of signaling

  12. 76 FR 43851 - Large Trader Reporting for Physical Commodity Swaps

    Science.gov (United States)

    2011-07-22

    ...,'' 75 FR 80174, December 21, 2010. With regard to the definition of ``reporting entity,'' FIA and the... reporting entities by limiting the set of reportable swaps, the Commission has amended the definition to... regulations, Better Markets suggested additional reporting fields, arguing that reporting entities should...

  13. A very large leiomyoma of the urethra: a case report.

    Science.gov (United States)

    Fedelini, Paolo; Chiancone, Francesco; Fedelini, Maurizio; Fabiano, Marco; Persico, Francesco; Di Lorenzo, Domenico; Meccariello, Clemente

    2017-02-28

    Leiomyomas are benign mesenchymal tumours of smooth muscle origin. They are the most common uterine masses in women of reproductive age group and may be related to the hormonal status. Urethral leiomyomas are very rare. According to the literature, the mean diameter of the urethral leiomyomas is 3.7 cm. We report a case of a very large leiomyoma of the urethra. A 40-year-old women woman was admitted to our department for a giant vaginal mass. She complained of haematuria, dysuria, recurrent urinary tract infections and dyspareunia. The physical evaluation demonstrated a 6 × 5.5 cm neoformation involving the distal tract of the urethra. The patient underwent an ultrasonography and then a magnetic resonance that suggested the diagnosis of leiomyoma. The neoformation was excised through a suburethral incision. The patient was discharged after 3 days and no intraoperative and postoperative complications occurred. The Foley catheter was removed after a week. The patient was continent to urine, and at 6 months follow-up, the patient was symptom free and no recurrences occurred.

  14. Asian International Students' College Experiences at Universities in the United States: Relationship between Perceived Quality of Personal Contact and Self-Reported Gains in Learning

    Science.gov (United States)

    Bista, Krishna K.

    2013-01-01

    This study examined associations between Asian international students' perceived quality of contact with faculty, administrative personnel and other students, and self-reported gains in areas identified in "College Students Experience Questionnaire." The sample included 705 Asian students from 25 research universities across the United…

  15. Directive versus Facilitative Peer Tutoring? A View on Students' Appraisal, Reported Learning Gains and Experiences within Two Differently-Tutored Learning Environments

    Science.gov (United States)

    Berghmans, Inneke; Michiels, Lotte; Salmon, Sara; Dochy, Filip; Struyven, Katrien

    2014-01-01

    The present study aimed to shed light on students' appraisal and reported learning gains in two differently-tutored learning environments (i.e. directively and facilitatively tutored). In order to investigate this, a quasi-experimental study was set up in the context of a clinical skills learning environment. Not only were participating…

  16. 26 CFR 1.453-12 - Allocation of unrecaptured section 1250 gain reported on the installment method.

    Science.gov (United States)

    2010-04-01

    ... purchased the property for $5000, held the property for several years, and took straight-line depreciation... gain on the sale of the property, $3000 is attributable to prior straight-line depreciation deductions..., $3000 was attributable to prior straight-line depreciation deductions and is unrecaptured section...

  17. Bilingual Resource Instruction for the Development of Gainful Employment Skills (Project BRIDGES). 1990-91 Final Evaluation Profile. OREA Report.

    Science.gov (United States)

    New York City Board of Education, Brooklyn, NY. Office of Research, Evaluation, and Assessment.

    An evaluation was done of New York City Public Schools' Bilingual Resource Instruction for the Development of Gainful Employment Skills Program (Project BRIDGES), which served poor immigrant high school students. The program operated at three Brooklyn high schools (Sheepshead Bay High School, Franklin D. Roosevelt High School, and South Shore High…

  18. Antenatal embolization of a large placental chorioangioma: a case report

    Directory of Open Access Journals (Sweden)

    Babic Inas

    2012-07-01

    Full Text Available Abstract Introduction A chorioangioma is the most common benign tumor of the placenta. The majority of pregnancies with chorioangiomas are asymptomatic. Pregnancies with large chorioangiomas are associated with maternal and fetal complications, such as growth restriction, cardiomegaly, congestive heart failure, fetal anemia, thrombocytopenia, nonimmune hydrops and intrauterine fetal death. There are several modalities of treatment published to date with various results. Our case was the third such case report published on the successful treatment with antenatal embolization of the feeding vessel of the chorioangioma. To the best of our knowledge, there have been no published cases about antenatal treatment of placental chorioangiomas in Saudi Arabia, or any other Gulf state. Case presentation We describe the case of a 28-year-old Arab woman diagnosed at 22 weeks of gestation with a chorioangioma. A glue material - enbucrilate (Histoacryl - was used for embolization of the feeding vessel. Intrauterine fetal blood transfusions were performed twice, as a treatment for fetal anemia. The fetus developed heart failure at 30 weeks of gestation. A Cesarean section was performed and the outcome was a live baby with right ventricular hypertrophy. The baby was admitted to our neonatal intensive care unit and discharged at 42 days following birth in a stable condition,with follow-up with our cardiology team. Conclusion In this case, we found that intrauterine embolization of the feeding vessel of a chorioangioma with Histoacryl was a valid treatment option that carried a small risk considering the good pregnancy outcome.

  19. Underrepresented minority high school and college students report STEM-pipeline sustaining gains after participating in the Loma Linda University Summer Health Disparities Research Program.

    Directory of Open Access Journals (Sweden)

    Lorena M Salto

    Full Text Available An urgent need exists for graduate and professional schools to establish evidence-based STEM (science, technology, engineering, and math pipeline programs to increase the diversity of the biomedical workforce. An untapped yet promising pool of willing participants are capable high school students that have a strong STEM interest but may lack the skills and the guided mentoring needed to succeed in competitive STEM fields. This study evaluates and compares the impact of the Loma Linda University (LLU Summer Health Disparities Research Program on high school (HS and undergraduate (UG student participants. The primary focus of our summer research experience (SRE is to enhance the research self-efficacy of the participants by actively involving them in a research project and by providing the students with personalized mentoring and targeted career development activities, including education on health disparities. The results of our study show that our SRE influenced terminal degree intent and increased participant willingness to incorporate research into future careers for both the HS and the UG groups. The quantitative data shows that both the HS and the UG participants reported large, statistically significant gains in self-assessed research skills and research self-efficacy. Both participant groups identified the hands-on research and the mentor experience as the most valuable aspects of our SRE and reported increased science skills, increased confidence in science ability and increased motivation and affirmation to pursue a science career. The follow-up data indicates that 67% of the HS participants and 90% of the UG participants graduated from college with a STEM degree; for those who enrolled in graduate education, 61% and 43% enrolled in LLU, respectively. We conclude that structured SREs can be highly effective STEM strengthening interventions for both UG and HS students and may be a way to measurably increase institutional and biomedical

  20. Large Brunner's gland adenoma: Case report and literature review

    Institute of Scientific and Technical Information of China (English)

    Alba Rocco; Pasquale Borriello; Debora Compare; Patrizia De Colibus; Loredana Pica; Alessandro Iacono; Gerardo Nardone

    2006-01-01

    Brunner's gland adenoma (BGA) is a very rare benign tumour of the duodenum, which is usually asymptomatic and discovered incidentally at endoscopy. Occasionally,this lesion may be large, causing upper gastrointestinal haemorrhage or intestinal obstruction. The case had a large Brunner's gland adenoma, presenting melena that was managed by endoscopic excision.

  1. Report from the 5th Workshop on Extremely Large Databases

    Directory of Open Access Journals (Sweden)

    Jacek Becla

    2012-03-01

    Full Text Available The 5th XLDB workshop brought together scientific and industrial users, developers, and researchers of extremely large data and focused on emerging challenges in the healthcare and genomics communities, spreadsheet-based large scale analysis, and challenges in applying statistics to large scale analysis, including machine learning. Major problems discussed were the lack of scalable applications, the lack of expertise in developing solutions, the lack of respect for or attention to big data problems, data volume growth exceeding Moore's Law, poorly scaling algorithms, and poor data quality and integration. More communication between users, developers, and researchers is sorely needed. A variety of future work to help all three groups was discussed, ranging from collecting challenge problems to connecting with particular industrial or academic sectors.

  2. Gaining control

    NARCIS (Netherlands)

    Enden, van der E.; Laan, van der R.

    2008-01-01

    The article reports on the efforts of companies to find a solution for tax risk management, tax accounting and being in control. In trying to find a solution, companies work towards an integrated tax control framework (TCF), a tax risk management and control environment embedded in the internal cont

  3. Gaining control

    NARCIS (Netherlands)

    Enden, van der E.; Laan, van der R.

    2008-01-01

    The article reports on the efforts of companies to find a solution for tax risk management, tax accounting and being in control. In trying to find a solution, companies work towards an integrated tax control framework (TCF), a tax risk management and control environment embedded in the internal cont

  4. Gaining control

    NARCIS (Netherlands)

    Enden, van der E.; Laan, van der R.

    2008-01-01

    The article reports on the efforts of companies to find a solution for tax risk management, tax accounting and being in control. In trying to find a solution, companies work towards an integrated tax control framework (TCF), a tax risk management and control environment embedded in the internal

  5. Colonic perforation by a large gallstone: A rare case report

    Directory of Open Access Journals (Sweden)

    Devin R. Halleran

    2014-01-01

    CONCLUSION: In cases of gallstones that manage to pass into the large intestine, it is prudent to attempt conservative measures for passage. Failure to do so should raise suspicion of a possible stricture, either benign or malignant, preventing its evacuation. Earlier surgical intervention should be considered in these cases.

  6. Large twisted ovarian fibroma in menopausal women: a case report.

    Science.gov (United States)

    Boujoual, Majdouline; Hakimi, Ihsan; Kouach, Jaouad; Oukabli, Mohamed; Moussaoui, Driss Rahali; Dehayni, Mohammed

    2015-01-01

    Ovarian fibroma is the most common benign solid tumors of the ovary, commonly misdiagnosed as uterine fibromaor as malignant ovarian tumors. It occurs generally in older perimenopausal and postmenopausal women. Occasionally large fibromas may undergo torsion causing acute abdominal pain. Doppler Ultrasonographyimaging is the choice study. CT and MRI are often needed for further characterization and differentiation from other solid ovarian masses. The choice treatment is surgical removal with intraoperative frozensection. Immunohistochemicalanalysis is recommended to rule out the differential diagnosis. Here we present a case of a postmenopausal woman with a large twisted ovarian fibroma reflecting diagnostic and management difficulties including potential misdiagnosis of the tumor as a malignant ovarian neoplasm that may influence the surgical approach.

  7. Advanced Large Area Plastic Scintillator Project (ALPS): Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, David V.; Reeder, Paul L.; Todd, Lindsay C.; Warren, Glen A.; McCormick, Kathleen R.; Stephens, Daniel L.; Geelhood, Bruce D.; Alzheimer, James M.; Crowell, Shannon L.; Sliger, William A.

    2008-02-05

    The advanced Large-Area Plastic Scintillator (ALPS) Project at Pacific Northwest National Laboratory investigated possible technological avenues for substantially advancing the state-of-the-art in gamma-ray detection via large-area plastic scintillators. The three predominant themes of these investigations comprised the following: * Maximizing light collection efficiency from a single large-area sheet of plastic scintillator, and optimizing hardware event trigger definition to retain detection efficiency while exploiting the power of coincidence to suppress single-PMT "dark current" background; * Utilizing anti-Compton vetoing and supplementary spectral information from a co-located secondary, or "Back" detector, to both (1) minimize Compton background in the low-energy portion of the "Front" scintillator's pulse-height spectrum, and (2) sharpen the statistical accuracy of the front detector's low-energy response prediction as impelmented in suitable energy-windowing algorithms; and * Investigating alternative materials to enhance the intrinsic gamma-ray detection efficiency of plastic-based sensors.

  8. Large scale PV plants - also in Denmark. Project report

    Energy Technology Data Exchange (ETDEWEB)

    Ahm, P. (PA Energy, Malling (Denmark)); Vedde, J. (SiCon. Silicon and PV consulting, Birkeroed (Denmark))

    2011-04-15

    Large scale PV (LPV) plants, plants with a capacity of more than 200 kW, has since 2007 constituted an increasing share of the global PV installations. In 2009 large scale PV plants with cumulative power more that 1,3 GWp were connected to the grid. The necessary design data for LPV plants in Denmark are available or can be found, although irradiance data could be improved. There seems to be very few institutional barriers for LPV projects, but as so far no real LPV projects have been processed, these findings have to be regarded as preliminary. The fast growing number of very large scale solar thermal plants for district heating applications supports these findings. It has further been investigated, how to optimize the lay-out of LPV plants. Under the Danish irradiance conditions with several winter months with very low solar height PV installations on flat surfaces will have to balance the requirements of physical space - and cost, and the loss of electricity production due to shadowing effects. The potential for LPV plants in Denmark are found in three main categories: PV installations on flat roof of large commercial buildings, PV installations on other large scale infrastructure such as noise barriers and ground mounted PV installations. The technical potential for all three categories is found to be significant and in the range of 50 - 250 km2. In terms of energy harvest PV plants will under Danish conditions exhibit an overall efficiency of about 10 % in conversion of the energy content of the light compared to about 0,3 % for biomass. The theoretical ground area needed to produce the present annual electricity consumption of Denmark at 33-35 TWh is about 300 km2 The Danish grid codes and the electricity safety regulations mention very little about PV and nothing about LPV plants. It is expected that LPV plants will be treated similarly to big wind turbines. A number of LPV plant scenarios have been investigated in detail based on real commercial offers and

  9. Report from the 6th Workshop on Extremely Large Databases

    Directory of Open Access Journals (Sweden)

    Daniel Liwei Wang

    2013-05-01

    Full Text Available Petascale data management and analysis remain one of the main unresolved challenges in today's computing. The 6th Extremely Large Databases workshop was convened alongside the XLDB conference to discuss the challenges in the health care, biology, and natural resources communities. The role of cloud computing, the dominance of file-based solutions in science applications, in-situ and predictive analysis, and commercial software use in academic environments were discussed in depth as well. This paper summarizes the discussions of this workshop.

  10. Working group report: Physics at the Large Hadron Collider

    Indian Academy of Sciences (India)

    D K Ghosh; A Nyffeler; V Ravindran

    2011-05-01

    This is a summary of the activities of the Physics at the LHC working group in the XIth Workshop on High Energy Physics Phenomenology (WHEPP-XI) held at the Physical Research Laboratory, Ahmedabad, India in January 2010. We discuss the activities of each sub-working group on physics issues at colliders such as Tevatron and Large Hadron Collider (LHC). The main issues discussed involve (1) results on W mass measurement and associated QCD uncertainties, (2) an attempt to understand the asymmetry measured at Tevatron in the top quark production, and (3) phenomenology of warped space dimension model.

  11. Large Multiloculated Splenic Mesothelial Cyst: A Rare Case Report

    Directory of Open Access Journals (Sweden)

    Roumina Hasan

    2015-12-01

    Full Text Available The mesothelial splenic cyst is a rare clinical entity, comprising <10% of all the primary splenic cysts. They usually present as a well-defined unilocular cystic lesion. We present a large multiloculated mesothelial splenic cyst in middle-aged women, which was radiologically indistinguishable from hydatid cyst. We discuss the importance of the clinical, radiological, and histopathological correlation in the diagnosis of this rare non-parasitic cyst of the spleen. [J Interdiscipl Histopathol 2015; 3(4.000: 146-148

  12. Genetic variation in body weight gain and composition in the intercross of Large (LG/J and Small (SM/J inbred strains of mice

    Directory of Open Access Journals (Sweden)

    Kramer Melissa G.

    1998-01-01

    Full Text Available Strain intercross experiments provide a powerful means for mapping genes affecting complex quantitative traits. We report on the genetic variability of the intercross of the Large (LG/J and Small (SM/J inbred mouse strains as a guide to gene mapping studies. Ten SM/J males were crossed to 10 LG/J females, after which animals were randomly mated to produce F1, F2, and F3 intercross generations. The 1632 F3 animals from 200 full-sib families were used to estimate heritabilities and genetic correlations of the traits measured. A subset of families was cross-fostered at birth to allow measurement of the importance of post-natal maternal effects. Data was collected on weekly body weight from one to 10 weeks and on organ weights, body weight, reproductive fat pad weight, and tail length at necropsy in the intercross generations. There was no heterosis for age-specific weights or necropsy traits, except that one-week weight was the highest in the F2 generation, indicating heterosis for maternal effect in the F1 mothers. We found moderate to high heritability for most age-specific weights and necropsy traits. Maternal effects were significant for age-specific weights from one to four weeks but disappeared completely at ten-week weight. Maternal effects for necropsy traits were low and not statistically significant. Age-specific weights showed a typical correlation pattern, with correlation declining as the difference in ages increased. Among necropsy traits, reproductive fat pad and body weights were very highly genetically correlated. Most other genetic correlations were low to moderate. The intercross between SM/J and LG/J inbred mouse strains provides a valuable resource for mapping quantitative trait loci for body size, composition, and morphology

  13. Large pool LMFBR design. Final report. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Wett, J. F.; Churchill, J. R.

    1979-03-01

    The design effort reported is an extension on past design effort and continuous concentration on those parts of the nuclear island unique to a commercial size pool type LMFBR. In particular, the work covers the reactor vessel, deck, rotating plugs, upper and lower internals, internal plenum separator system, IHX, pumps, cold traps, intermediate system layout, containment/confinement system, plot plan, and residual heat removal systems. Preliminary thermal, hydraulic, stress, and system analyses are also presented.

  14. A large gastrointestinal stromal tumor of duodenum: a case report

    Directory of Open Access Journals (Sweden)

    Hadi Ahmadi Amoli

    2014-01-01

    Case presentation: The patient is a forty six years old man. He complained of frequent colic pain in left upper quadrant of abdomen for two months before admitting to the hospital. The pain resolved spontaneously after a few hours. This situation almost has been repeated every week. The patient had severe repeated melena and faint for two weeks. As soon as the patient was entered the Sina Hospital in 2012, supportive care was started. Then upper gastrointestinal endoscopy was performed for him and the bleeding point was detected. Also abdominal and pelvic computed tomography with oral and intravenous contrast was done. Finally the patient was operated on tumor diagnosis in duodenal area according to classic Whipple procedure. Conclusion: Gastrointestinal bleeding is the most common symptom of gastrointestinal stromal tumors. The bleeding is minimal and chronic. It will be progress to sudden and severe bleeding. Diagnosis is done by upper gastrointestinal endoscopy and biopsy. The large tumors with high mitotic

  15. A superconducting large-angle magnetic suspension. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Downer, J.R.; Anastas, G.V. Jr.; Bushko, D.A.; Flynn, F.J.; Goldie, J.H.; Gondhalekar, V.; Hawkey, T.J.; Hockney, R.L.; Torti, R.P.

    1992-12-01

    SatCon Technology Corporation has completed a Small Business Innovation Research (SBIR) Phase 2 program to develop a Superconducting Large-Angle Magnetic Suspension (LAMS) for the NASA Langley Research Center. The Superconducting LAMS was a hardware demonstration of the control technology required to develop an advanced momentum exchange effector. The Phase 2 research was directed toward the demonstration for the key technology required for the advanced concept CMG, the controller. The Phase 2 hardware consists of a superconducting solenoid ('source coils') suspended within an array of nonsuperconducting coils ('control coils'), a five-degree-of-freedom positioning sensing system, switching power amplifiers, and a digital control system. The results demonstrated the feasibility of suspending the source coil. Gimballing (pointing the axis of the source coil) was demonstrated over a limited range. With further development of the rotation sensing system, enhanced angular freedom should be possible.

  16. Large cardiac fibroma and teratoma in children- case reports.

    Science.gov (United States)

    Jha, Neerod Kumar; Kiraly, Laszlo; Tamas, Csaba; Talo, Haitham; Khan, Mohammad Daud; El Badaoui, Hazem; Jain, Anurag; Hammad, Azzam

    2015-03-22

    Primary cardiac tumours in paediatric population are an unusual occurrence. Although, majority of such tumours are benign (90%), the frequency and type of cardiac tumours in this age group is different from the adult population. There are several consecutive series published in the last decade on cardiac neoplasms. Therefore, this is not only an effort to contribute to the existing literature for better understanding and management of similar patients but also to highlight the importance of early detection either by prenatal imaging or careful evaluation of differential diagnosis of common symptoms. We herein, describe two infants with large cardiac tumours (fibroma and teratoma) both arising from the interventricular septum and underwent surgical excision. A possible role of cardiac remodeling in myocardial tissue healing after extensive tissue resection in such patients is hypothesised through available experimental or limited clinical information.

  17. Innovative design approaches for large wind turbine blades : final report.

    Energy Technology Data Exchange (ETDEWEB)

    2004-05-01

    The goal of the Blade System Design Study (BSDS) was investigation and evaluation of design and manufacturing issues for wind turbine blades in the one to ten megawatt size range. A series of analysis tasks were completed in support of the design effort. We began with a parametric scaling study to assess blade structure using current technology. This was followed by an economic study of the cost to manufacture, transport and install large blades. Subsequently we identified several innovative design approaches that showed potential for overcoming fundamental physical and manufacturing constraints. The final stage of the project was used to develop several preliminary 50m blade designs. The key design impacts identified in this study are: (1) blade cross-sections, (2) alternative materials, (3) IEC design class, and (4) root attachment. The results show that thick blade cross-sections can provide a large reduction in blade weight, while maintaining high aerodynamic performance. Increasing blade thickness for inboard sections is a key method for improving structural efficiency and reducing blade weight. Carbon/glass hybrid blades were found to provide good improvements in blade weight, stiffness, and deflection when used in the main structural elements of the blade. The addition of carbon resulted in modest cost increases and provided significant benefits, particularly with respect to deflection. The change in design loads between IEC classes is quite significant. Optimized blades should be designed for each IEC design class. A significant portion of blade weight is related to the root buildup and metal hardware for typical root attachment designs. The results show that increasing the number of blade fasteners has a positive effect on total weight, because it reduces the required root laminate thickness.

  18. Working group report: Dictionary of Large Hadron Collider signatures

    Indian Academy of Sciences (India)

    A Belyaev; I A Christidi; A De Roeck; R M Godbole; B Mellado; A Nyffeler; C Petridou; D P Roy

    2009-01-01

    We report on a plan to establish a `Dictionary of LHC Signatures', an initiative that started at the WHEPP-X workshop in Chennai, January 2008. This study aims at the strategy of distinguishing 3 classes of dark matter motivated scenarios such as -parity conserved supersymmetry, little Higgs models with -parity conservation and universal extra dimensions with KK-parity for generic cases of their realization in a wide range of the model space. Discriminating signatures are tabulated and will need a further detailed analysis.

  19. Measuring How College Affects Students: Social Desirability and Other Potential Biases in College Student Self-Reported Gains

    Science.gov (United States)

    Bowman, Nicholas A.; Hill, Patrick L.

    2011-01-01

    Colleges and universities are increasingly using national surveys to assess their students' learning and development. Given the importance of the first year of college for student adjustment and retention (Tinto, 1993), some of these surveys are designed specifically to gauge the experiences and outcomes of first-year students. These large-scale…

  20. Final Report: "Large-Eddy Simulation of Anisotropic MHD Turbulence"

    Energy Technology Data Exchange (ETDEWEB)

    Zikanov, Oleg

    2008-06-23

    To acquire better understanding of turbulence in flows of liquid metals and other electrically conducting fluids in the presence of steady magnetic fields and to develop an accurate and physically adequate LES (large-eddy simulation) model for such flows. The scientific objectives formulated in the project proposal have been fully completed. Several new directions were initiated and advanced in the course of work. Particular achievements include a detailed study of transformation of turbulence caused by the imposed magnetic field, development of an LES model that accurately reproduces this transformation, and solution of several fundamental questions of the interaction between the magnetic field and fluid flows. Eight papers have been published in respected peer-reviewed journals, with two more papers currently undergoing review, and one in preparation for submission. A post-doctoral researcher and a graduate student have been trained in the areas of MHD, turbulence research, and computational methods. Close collaboration ties have been established with the MHD research centers in Germany and Belgium.

  1. Spontaneous regression of a large hepatocellular carcinoma: case report

    Directory of Open Access Journals (Sweden)

    Alqutub, Adel

    2011-01-01

    Full Text Available The prognosis of untreated advanced hepatocellular carcinoma (HCC is grim with a median survival of less than 6 months. Spontaneous regression of HCC has been defined as the disappearance of the hepatic lesions in the absence of any specific therapy. The spontaneous regression of a very large HCC is very rare and limited data is available in the English literature. We describe spontaneous regression of hepatocellular carcinoma in a 65-year-old male who presented to our clinic with vague abdominal pain and weight loss of two months duration. He was found to have multiple hepatic lesions with elevation of serum alpha-fetoprotein (AFP level to 6,500 µg/L (normal <20 µg/L. Computed tomography revealed advanced HCC replacing almost 80% of the right hepatic lobe. Without any intervention the patient showed gradual improvement over a period of few months. Follow-up CT scan revealed disappearance of hepatic lesions with progressive decline of AFP levels to normal. Various mechanisms have been postulated to explain this rare phenomenon, but the exact mechanism remains a mystery.

  2. Optical very large array (OVLA) prototype telescope: status report and perspective for large mosaic mirrors

    Science.gov (United States)

    Dejonghe, Julien; Arnold, Luc; Lardiere, Olivier; Berger, Jean-Pierre; Cazale, C.; Dutertre, S.; Kohler, D.; Vernet, D.

    1998-08-01

    The OVLA will be a kilometric-size interferometric array of N equals 27 or more 1.5 m telescopes. It is expected to provide visible to infra-red snap-shot images, containing in densified pupil mode N(superscript 2) 10(superscript -4) arc-second wide resolved elements in yellow light. The prototype telescope is under construction at Observatoire de Haute Provence and will be connected in 2000 to the GI2T, Grand Interferometre a 2 Telescopes, thus upgraded to a GI3T. The prototype telescope has a spherical mount, well suited for multi- aperture interferometric work, and a thin active 1.5 m f/1.7 mirror weighting only 180 kg with the active cell. This meniscus-shaped mirror, made of low-cost ordinary window glass, is only 24 mm thick and supported by 32 actuators. We describe the telescope optical concept with emphasis on opto-mechanical aspects and the test results of the active optics system. We also discuss the application of this mirror concept to large mosaic mirrors of moderate cost.

  3. Management of Large Tongue Schwannoma – A Short Report

    Directory of Open Access Journals (Sweden)

    Jayanta Medhi

    2016-03-01

    Full Text Available Schwannoma is a benign nerve sheath tumor composed of schwann cells. Oral cavity is a rare site for schwannomas, tongue being the most common location. Here we are presenting a case of a young adult who presented with a huge swelling in the tongue which was removed by mandibulotomy approach and pre-operative tracheostomy. A 22-year-old male patient presented to the outpatient department with a history of swelling in the tongue for the last 4 years with progressive difficulty in swallowing food and change of voice over the last few months. Upon examination a large swelling was observed on the posterior part of the tongue compromising the oropharyngeal inlet. The approximate size of the swelling was 5cmx4cm. After proper clinical evaluation the patient was advised to obtain a magnetic resonance imaging (MRI study of the oral cavity, which showed it to be a nerve sheath tumor (Schwannoma originating from the hypoglossal nerve branch. The patient was admitted for surgery. As difficult intubation was anticipated, pre-operative tracheostomy was performed. The tongue mass was approached by right paramedian mandibulotomy using a transcervical lip split incision. Post operative histopathological examination of the removed specimen showed hypercellular ‘Antony A’ area with plump spindle cells and hypocellular ‘Antony B’ area in a Hematoxylin & eosin stain (200x. This confirmed the diagnosis for a schwannoma. As each and every case is unique in its presentation, so is the management. The idea of presenting the above case is to emphasise the role of selection for the proper approach and foresee the preventable complications while working around the airway.

  4. Burn-injured adolescents report gaining multiple developmental benefits and improved life skills as a result of burn camp attendance.

    Science.gov (United States)

    Rimmer, Ruth Brubaker; Pressman, Melissa S; Takach, Oliver P; Bay, R Curtis; Croteau, Renee; Hansen, Linda D; Foster, Kevin N; Caruso, Daniel M

    2012-01-01

    Anecdotally, burn camp has been reported to be a positive developmental and rehabilitative experience for attendees; there is little empirical data to support this belief. This study sought to explore whether burn camp either directly or indirectly elicits positive development outcomes in pediatric burn survivors or increases their psychosocial well-being and achievement. The Youth Experience Survey 2.0, a 66-item self-report inventory designed to measure developmental experiences in an organized youth activity, was administered to children aged 11 to 18 years attending summer burn camp. One hundred and ten burn-injured youth, 58 male and 52 female, reported that burn camp had positively impacted their lives through improved identity exploration, goal-setting and problem-solving abilities, increased physical activity, communication, emotional regulation, and time management skills (P camp for more than 5 years resulted in greater improvement. Study results support the burn camp experience as a far-reaching and positive developmental activity. Participants credited the camp experience with helping them with identity formation and reflection, improved social interactions, and increased initiative; all positive developmental outcomes for youth. Results suggest that burn camp participation not only helps burn-injured youth to deal with their burns but also assists them in the development of social and basic life skills, which will allow them to navigate the transition from youth to adulthood, more effectively and successfully.

  5. A flexible and high-performance bidirectional optical amplifier with all optical gain control using ASE noise path through multi-port circulators

    Institute of Scientific and Technical Information of China (English)

    An Vu Tran; Chang-Joon Chae; Rodney S. Tucker

    2003-01-01

    We report a flexible all-optical gain controlled bidirectional optical amplifier. The device achieves constant gain and low noise figure over a large input power range. Moreover, the device removes Rayleigh backscattered light and amplifier noise.

  6. A gain-coefficient switched Alexandrite laser

    NARCIS (Netherlands)

    Lee, Chris J.; Slot, van der Peter J.M.; Boller, Klaus-J.

    2013-01-01

    We report on a gain-coefficient switched Alexandrite laser. An electro-optic modulator is used to switch between high and low gain states by making use of the polarization dependent gain of Alexandrite. In gain-coefficient switched mode, the laser produces 85 ns pulses with a pulse energy of 240 mJ

  7. A gain-coefficient switched Alexandrite laser

    CERN Document Server

    Lee, Chris J; Boller, Klaus-J

    2012-01-01

    We report on a gain-coefficient switched Alexandrite laser. An electro-optic modulator is used to switch between high and low gain states by making use of the polarization dependent gain of Alexandrite. In gain-coefficient switched mode, the laser produces 85 ns pulses with a pulse energy of 240 mJ at a repetition rate of 5 Hz.

  8. A sourcebook of methods and procedures for monitoring and reporting anthropogenic greenhouse gas emissions and removals associated with deforestation, gains and losses of carbon stocks in forests remaining forests, and forestation

    NARCIS (Netherlands)

    Achard, F.; Boschetti, L.; Brown, S.; Brady, M.; DeFries, R.; Grassi, G.; Herold, M.; Mollicone, D.; Mora, B.; Pandey, D.; Souza, C.

    2014-01-01

    A sourcebook of methods and procedures for monitoring and reporting anthropogenic greenhouse gas emissions and removals associated with deforestation, gains and losses of carbon stocks in forests remaining forests, and forestation

  9. GOFC-GOLD REDD Sourcebook, COP-18 release - A sourcebook of methods and procedures for monitoring and reporting anthropogenic greenhouse gas emissions and removals associated with deforestation, gains and losses of carbon stocks in forests remaining forests, and forestation

    NARCIS (Netherlands)

    Achard, F.; Brown, S.; Brady, M.; DeFries, R.; Grassi, G.; Herold, M.; Mollicone, D.; Mora, B.; Pandey, D.; Souza, C.

    2012-01-01

    A sourcebook of methods and procedures for monitoring and reporting anthropogenic greenhouse gas emissions and removals associated with deforestation, gains and losses of carbon stocks in forests remaining forests, and forestation

  10. 大型土建工程管理中成本控制增益均衡模型%The Cost Control Gain Equilibrium Model of The Large Civil Engineering Management

    Institute of Scientific and Technical Information of China (English)

    胡晓娟

    2015-01-01

    The increased cost of construction. For this, put forward a large civil engineering management cost control gain equilibrium model, using the data from the civil engineering construction of construction cost estimates, cost control gain balance model is established, through the forecast data and actual cost error gain balance calculation, the process of the project cost control for minimum error value. The simulation experiment indicates that the gain equalization algorithm can effectively improve the efficiency of soil construction cost management, reduce the error of cost management at the same time, with the most effective the most reasonable method, to budget, cost effective for the management of civil engineering to provide better protection.%提出大型土建工程管理中成本控制增益均衡模型,利用土建工程相关施工数据,对施工建设做成本预估,建立成本控制增益均衡模型,通过预估数据与实际成本误差进行增益均衡计算,使工程成本控制得到最小误差值的过程.仿真试验表明,这种增益均衡算法更能有效的提高土建工成本管理的效率,同时降低成本管理的误差,以最有效最合理的方法,对成本进行预算,有效的为土建工程的管理提供更好的保障.

  11. Reported methodologic quality and discrepancies between large and small randomized trials in meta-analyses

    DEFF Research Database (Denmark)

    Kjaergard, L L; Villumsen, J; Gluud, C

    2001-01-01

    To explore whether reported methodologic quality affects estimated intervention effects in randomized trials and contributes to discrepancies between the results of large randomized trials and small randomized trials in meta-analyses....

  12. 76 FR 81481 - Agency Information Collection Activities: Notice of Intent to Renew Collection, Large Trader Reports

    Science.gov (United States)

    2011-12-28

    ... From the Federal Register Online via the Government Publishing Office COMMODITY FUTURES TRADING COMMISSION Agency Information Collection Activities: Notice of Intent to Renew Collection, Large Trader Reports AGENCY: Commodity Futures Trading Commission. ACTION: Notice SUMMARY: The Commodity...

  13. Relationships among hepatitis C virus, hepatocellular carcinoma, and diffuse large B cell lymphoma: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Byun, Hyuk Jun; Kim, Seong Hoon [Dept. of Radiology, Daegu Fatima Hospital, Daegu (Korea, Republic of)

    2015-07-15

    Hepatitis C virus (HCV) is one of the main causes of hepatocellular carcinoma (HCC). Recent studies have reported various associations between HCV and the incidence of non-Hodgkin's lymphoma. We report the radiologic findings in a rare case of simultaneous occurrence of HCC and diffuse large B cell lymphoma in a HCV carrier.

  14. Asthma Triggers: Gain Control

    Science.gov (United States)

    ... Search Asthma Contact Us Share Asthma Triggers: Gain Control Breathing Freely: Controlling Asthma Triggers This video features ... Air Quality: Biological Pollutants Help Your Child Gain Control Over Asthma Top of Page Molds About Molds ...

  15. Determination of optimal gains for constrained controllers

    Energy Technology Data Exchange (ETDEWEB)

    Kwan, C.M.; Mestha, L.K.

    1993-08-01

    In this report, we consider the determination of optimal gains, with respect to a certain performance index, for state feedback controllers where some elements in the gain matrix are constrained to be zero. Two iterative schemes for systematically finding the constrained gain matrix are presented. An example is included to demonstrate the procedures.

  16. RADON DIAGNOSTIC MEASUREMENT GUIDANCE FOR LARGE BUILDINGS - VOLUME 1. TECHNICAL REPORT

    Science.gov (United States)

    The report discusses the development of radon diagnostic procedures and mitigation strategies applicable to a variety of large non-residential buildings commonly found in Florida. The investigations document and evaluate the nature of radon occurrence and entry mechanisms for rad...

  17. Alignment of Scores on Large-Scale Assessments and Report-Card Grades

    Science.gov (United States)

    Ross, John A.; Gray, Peter

    2008-01-01

    We examined how much agreement there was between scores from large-scale mandated assessments and report-card grades for 14,776 students in grades 3, 6, and 9 of a district in which conditions were conducive to alignment of assessments. We found significant mean differences between internal and external assessments: effect sizes were 0.29 to 0.63…

  18. Large cavernous hemangioma of the adrenal gland: Laparoscopic treatment. Report of a case

    Directory of Open Access Journals (Sweden)

    A. Agrusa

    2015-01-01

    Conclusion: Laparoscopic adrenalectomy is considered the standard treatment in case of diagnosis of benign lesions. In this case report we discussed a large adrenal cavernous hemangioma treated with laparoscopic approach. Fundamental is the study of preoperative endocrine disorders and radiologic findings to exclude signs of malignancy.

  19. RADON DIAGNOSTIC MEASUREMENT GUIDANCE FOR LARGE BUILDINGS - VOLUME 1. TECHNICAL REPORT

    Science.gov (United States)

    The report discusses the development of radon diagnostic procedures and mitigation strategies applicable to a variety of large non-residential buildings commonly found in Florida. The investigations document and evaluate the nature of radon occurrence and entry mechanisms for rad...

  20. Flow and wakes in large wind farms: Final report for UpWind WP8

    DEFF Research Database (Denmark)

    Barthelmie, Rebecca Jane; Frandsen, Sten Tronæs; Rathmann, Ole;

    This report summarises the research undertaken through the European Commission funded project UpWind Wp8:Flow. The objective of the work was to develop understanding of flow in large wind farms and to evaluate models of power losses due to wind turbine wakes focusing on complex terrain and offsho...

  1. In vivo reflectance confocal microscopy features of a large cell acanthoma: report of a case.

    Science.gov (United States)

    Shahriari, Neda; Grant-Kels, Jane M; Rabinovitz, Harold S; Oliviero, Margaret; Scope, Alon

    2016-07-01

    Reflectance confocal microscopy (RCM) is an FDA approved noninvasive optical imaging technique that acquires cellular level-resolution skin images in vivo. Herein, we report a case of histopathologically proven large cell acanthoma (LCA) whose RCM features simulate those of squamous cell carcinoma in situ.

  2. Flow and wakes in large wind farms. Final report for UpWind WP8

    Energy Technology Data Exchange (ETDEWEB)

    Barthelmie, R.J.; Frandsen, S.T.; Rathmann, O. (Risoe DTU (Denmark)); Hansen, K. (Technical Univ. of Denmark (DTU), Kgs. Lyngby (Denmark)); Politis, E.; Prospathopoulos, J. (CRES (Greece)); Schepers, J.G. (ECN, Petten (Netherlands)); Rados, K. (NTUA, Athens (Greece)); Cabezon, D. (CENER, Sarriguren (Spain)); Schlez, W.; Neubert, A.; Heath, M. (Garrad Hassan and Partners (Germany) (United Kingdom))

    2011-02-15

    This report summarises the research undertaken through the European Commission funded project UpWind Wp8:Flow. The objective of the work was to develop understanding of flow in large wind farms and to evaluate models of power losses due to wind turbine wakes focusing on complex terrain and offshore. A crosscutting activity was to improve and compare the performance of computational fluid dynamics models with wind farm models. The report contains 6 deliverable reports and guideline to wind farm wake analysis as appendices. (Author)

  3. Endoscopic Resection of a Large Colonic Lipoma: Case Report and Review of Literature

    Directory of Open Access Journals (Sweden)

    Girolamo Geraci

    2010-02-01

    Full Text Available Colonic lipomas are uncommon, benign, submucosal adipose tumors that are usually asymptomatic. Large lipomas can cause symptoms such as constipation, abdominal pain, rectal bleeding and intussusception. We report the case of a 60-year-old man with a history of lower abdominal pain and pseudoobstructive symptoms. Colonoscopy revealed a large polypoid sessile lesion in the sigma. We used a standardized technique of polypectomy, preceded by submucosal injection of dilute 5 ml polygelin with epinephrine 1:10,000 solution, to fully resect large colonic lipomas. The lipoma size was 3.5 cm. No bleeding or perforation developed. Histology showed the polyp to be a submucosul lipoma. On follow-up, there was no residual lesion. Colonic lipomas larger than 2 cm can be safely and efficaciously removed using electrosurgical snare polypectomy technique. The technique of submucosal injection before resection and using an electrocautery snare appears to be safe and reduces the risk of perforation reported in the literature.

  4. Maternal glycated haemoglobin, pre-gestational weight, pregnancy weight gain and risk of large-for-gestational-age babies: a Danish cohort study of 209 singleton Type 1 diabetic pregnacies

    DEFF Research Database (Denmark)

    Nielsen, G.L.; Dethlefsen, Claus; Møller, M.

    2007-01-01

    Aims To examine the association between maternal glycated haemoglobin in the second half of diabetic pregnancies and the relative risk of delivering large-for-gestational-age (LGA) babies, controlling for maternal body mass index (BMI) before pregnancy, weight gain, age, White class and smoking...... to pregnancies with pre-pregnancy BMI > 23 kg/m2. We found no association between HbA1c and risk of delivering an LGA baby in pregnancies with lower BMI. Conclusion The positive association between glycated haemoglobin and birth of an LGA baby seems to be restricted to women with BMI > 23 kg/m2....... habits. Methods We identified all pregnant diabetic women in North Jutland County, Denmark from 1985 to 2003. Data on HbA1c values from the 20th gestational week to term were collected from medical records and the babies were classified as large, normal or small for gestational age. The association...

  5. A Natural Language Processing Tool for Large-Scale Data Extraction from Echocardiography Reports

    Science.gov (United States)

    Jonnalagadda, Siddhartha R.

    2016-01-01

    Large volumes of data are continuously generated from clinical notes and diagnostic studies catalogued in electronic health records (EHRs). Echocardiography is one of the most commonly ordered diagnostic tests in cardiology. This study sought to explore the feasibility and reliability of using natural language processing (NLP) for large-scale and targeted extraction of multiple data elements from echocardiography reports. An NLP tool, EchoInfer, was developed to automatically extract data pertaining to cardiovascular structure and function from heterogeneously formatted echocardiographic data sources. EchoInfer was applied to echocardiography reports (2004 to 2013) available from 3 different on-going clinical research projects. EchoInfer analyzed 15,116 echocardiography reports from 1684 patients, and extracted 59 quantitative and 21 qualitative data elements per report. EchoInfer achieved a precision of 94.06%, a recall of 92.21%, and an F1-score of 93.12% across all 80 data elements in 50 reports. Physician review of 400 reports demonstrated that EchoInfer achieved a recall of 92–99.9% and a precision of >97% in four data elements, including three quantitative and one qualitative data element. Failure of EchoInfer to correctly identify or reject reported parameters was primarily related to non-standardized reporting of echocardiography data. EchoInfer provides a powerful and reliable NLP-based approach for the large-scale, targeted extraction of information from heterogeneous data sources. The use of EchoInfer may have implications for the clinical management and research analysis of patients undergoing echocardiographic evaluation. PMID:27124000

  6. Gastric Collision Tumor Consisting of Mucinous Carcinoma and Large Cell Neuroendocrine Carcinoma: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Su Min; Lee, Ye Ri; Han, Eun Mee; Yeon, Jae Woo; Yoo, Jin Young; Choi, Jong Mun; Sim, Ji Ye [Bundang Jesaeng General Hospital, Seongnam (Korea, Republic of)

    2010-06-15

    The concurrence of two different pathological tumors of the stomach is infrequent. Even rarer is a gastric collision tumor of both tumor types. Although there have been a few reported cases of gastric collision tumors that consisted of an adenocarcinoma and neuroendocrine carcinoma, to the best of our knowledge, there is no documented case report of a gastric collision tumor consisting of a mucinous carcinoma and large cell neuroendocrine carcinoma. We report a case of gastric collision tumor, consisting of a mucinous carcinoma and large cell neuroendocrine carcinoma that presented as abdominal discomfort in a 64-year-old man. This finding draws attention to the related findings from previous studies on gastric collision tumors

  7. Paul Scherrer Institute Scientific and Technical Report 1999. Volume VI: Large Research Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Foroughi, Fereydoun; Bercher, Renate; Buechli, Carmen; Meyer, Rosa [eds.

    2000-07-01

    The department GFA (Grossforschungsanlagen, Large Research Facilities) has been established in October 1998. Its main duty is operation, maintenance and development of the PSI accelerators, the spallation neutron source and the beam transport systems for pions and muons. A large effort of this group concerns the planning and co-ordination of new projects like e.g. the assembly of the synchrotron light source (SLS), design studies of a new proton therapy facility, the ultracold neutron source and a new intensive secondary beam line for low energy muons. A large fraction of this report is devoted to research especially in the field of materials Science. The studies include large scale molecular dynamics computer simulations on the elastic and plastic behavior of nanostructured metals, complemented by experimental mechanical testing using micro-indentation and miniaturized tensile testing, as well as microstructural characterisation and strain field mapping of metallic coatings and thin ceramic layers, the latter done with synchrotron radiation.

  8. Reconstruction of large maxillary defect with the use of vastus lateralis (VL free flap. Case report

    Directory of Open Access Journals (Sweden)

    Nikolaos Papadogeorgakis, Vlasios Oktseloglou, Eleni Pappa, Petros Spyriounis

    2010-08-01

    Full Text Available Large defects of the maxilla, following ablative surgery, significantly affect functions such as chewing, swallowing, speech and also the aesthetics. Reconstruction of soft tissues and bone defects can be achieved, either with the use of an obturator, or with free flaps. In the literature there is no sufficient evidence on the primacy of the one or the other method. The choice depends on the judgment, the experience and the ability of the surgical team. In recent years, the use of anterolateral thigh (ALTfree flap for reconstruction of large defects of the maxillary region, has gained a lot of popularity. The vastuslateralis free flap (VL is a variation of ALT. VL’s advantages include long pedicle, easier harvesting, and fewer anatomical variations. We present a case of a 75 year old male with recurrent squamous cell carcinoma of the medial canthal region, invading the maxillary bone, the medial wall and the floor of the orbit. The patient underwent a total maxillectomy, orbital exenteration, and reconstruction with vastus lateralis free flap.

  9. MANTA, a novel plug-based vascular closure device for large bore arteriotomies: technical report.

    Science.gov (United States)

    van Gils, Lennart; Daemen, Joost; Walters, Greg; Sorzano, Todd; Grintz, Todd; Nardone, Sam; Lenzen, Mattie; De Jaegere, Peter P T; Roubin, Gary; Van Mieghem, Nicolas M

    2016-09-18

    Catheter-based interventions have become a less invasive alternative to conventional surgical techniques for a wide array of cardiovascular diseases but often create large arteriotomies. A completely percutaneous technique is attractive as it may reduce the overall complication rate and procedure time. Currently, large bore arteriotomy closure relies on suture-based techniques. Access-site complications are not uncommon and often seem related to closure device failure. The MANTA VCD is a novel collagen-based closure device that specifically targets arteriotomies between 10 and 22 Fr. This technical report discusses the MANTA design concept, practical instructions for use and preliminary clinical experience.

  10. Hydrologic studies in wells open through large intervals. Annual report, 1992

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-31

    This report describes and summarizes activities, data, and preliminary data interpretation from the INEL Oversight Program R&D-1 project titled ``Hydrologic Studies In Wells Open Through Large Intervals.`` The project is designed to use a straddle-packer system to isolate, hydraulically test, and sample specific intervals of monitoring wells that are open (uncased, unscreened) over large intervals of the Snake River Plain aquifer. The objectives of the project are to determine and compare vertical variations in water quality and aquifer properties that have previously only been determined in an integrated fashion over the entire thickness of the open interval of the observation wells.

  11. Clip reconstruction of a large right MCA bifurcation aneurysm. Case report

    Directory of Open Access Journals (Sweden)

    Giovani A.

    2014-06-01

    Full Text Available We report a case of complex large middle cerebral artery (MCA bifurcation aneurysm that ruptured during dissection from the very adherent MCA branches but was successfully clipped and the MCA bifurcation reconstructed using 4 Yasargill clips. Through a right pterional craniotomy the sylvian fissure was largely opened as to allow enough workspace for clipping the aneurysm and placing a temporary clip on M1. The pacient recovered very well after surgery and was discharged after 1 week with no neurological deficit. Complex MCA bifurcation aneurysms can be safely reconstructed using regular clips, without the need of using fenestrated clips or complex by-pass procedures.

  12. Multiple Large Perineural (Tarlov) Cysts in the Sacrum of a Cadaver: A Case Report and Review.

    Science.gov (United States)

    Gonzales, Jocelyn; Iwanaga, Joe; Topale, Nitsa; Oskouian, Rod J; Tubbs, R Shane

    2017-04-12

    Tarlov or perineural cysts are cerebrospinal fluid (CSF)-filled sacs found between the perineurium and epineurium of the nerve roots. It is still unsure whether the origin of these cysts is intradural or extradural. They can either be asymptomatic or create a variety of negative impacts on comfort and quality of life. In this case report, we describe the presentation of multiple Tarlov cysts including one large cyst discovered during a routine cadaveric spinal dissection and the relevant and related literature. To our knowledge, this is the only cadaveric case report of Tarlov cysts and offers an interesting window into their anatomy.

  13. Large-scale building integrated photovoltaics field trial. First technical report - installation phase

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This report summarises the results of the first eighteen months of the Large-Scale Building Integrated Photovoltaic Field Trial focussing on technical aspects. The project aims included increasing awareness and application of the technology, raising the UK capabilities in application of the technology, and assessing the potential for building integrated photovoltaics (BIPV). Details are given of technology choices; project organisation, cost, and status; and the evaluation criteria. Installations of BIPV described include University buildings, commercial centres, and a sports stadium, wildlife park, church hall, and district council building. Lessons learnt are discussed, and a further report covering monitoring aspects is planned.

  14. A large tuberculous abscess mimicking a retroperitoneal cystic mass: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kwang Suk; Cha, Seung Hwan; Ahn, Ji Hyun; Cho, Mi Yeon [Yonsei University Wonju College of Medicine, Wonju Severance Christian Hospital, Wonju (Korea, Republic of)

    2015-03-15

    Large cystic masses originating from the retroperitoneal space are rare, and cystic tumors are often considered preferentially in the differential diagnosis. However, it is difficult to make a correct diagnosis. A 55-year-old man presented with a palpable abdominal mass. A computed tomography (CT) scan detected a mass mimicking a large cystic tumor in the retroperitoneal space anterior to the psoas muscle. The mass had an enhanced outer margin, an irregular inner margin, and several surrounding necrotic lymph nodes. However, histopathologic examination followed by an exploratory laparotomy confirmed that the mass was consistent with a tuberculous (TB) abscess. A retroperitoneal TB abscess without spinal or active pulmonary TB is very rare. To the best of our knowledge, there are no published reports of a retroperitoneal TB abscess confirmed by both CT scan and surgical pathology in the Korean literature. We report a rare case of a huge retroperitoneal TB abscess that can mimic a cystic tumor.

  15. Breast schwannoma in a patient with diffuse large B-cell lymphoma: a case report

    Directory of Open Access Journals (Sweden)

    Salihoglu Ayse

    2012-12-01

    Full Text Available Abstract Introduction Schwannomas are mostly benign tumors arising from Schwann cells of the nerve sheaths. Breast schwannomas are very rare and account for only 2.6% of cases. As far as we know this is the first reported case of breast schwannoma discovered in a patient with diffuse large B-cell lymphoma. The breast schwannoma was evaluated with positron emission tomography and it exhibited moderate 18F-fluorodeoxyglucose uptake. Case presentation We present the case of a breast schwannoma in a 63-year-old Caucasian woman who was diagnosed with diffuse large B-cell lymphoma. Conclusion Imaging modalities including positron emission tomography-computed tomography failed to distinguish breast schwannoma from diffuse large B-cell lymphoma involvement of the breast.

  16. [Neuroendocrine carcinoma with large cells of the breast: case report and review of the literature].

    Science.gov (United States)

    Bourhaleb, Z; Uri, N; Haddad, H; Azzouzi, S; Zamiati, S; Benchakroun, N; Tawfiq, N; Jouhadi, H; Sahraoui, S; Benider, A

    2009-12-01

    Neuroendocrine carcinoma with large cells is a slightly different tumor from the high rank of malignity. We report a case of breast localization in a 28-year-old patient. It is a locally advanced classified T4dN1M0 tumor that required neoadjuvant chemotherapy. The clinical answer was 75% of the level of the tumor. A standard surgery mastectomy with axillary lymph node dissection was realized, followed by external radiotherapy. The anatomopathologic and the immuno-histochemical study of the operational part confirmed the diagnosis of neuroendocrine carcinoma with large cells expressing the progesterone receptor. The patient is subjected to adjuvant hormonal treatment. After a 12 months retreat, a complete remission is maintained. Considering the scarcity of neuroendocrine carcinoma with large cells of the breast, the therapeutic standard is not yet available and the forecast remains difficult to determine.

  17. Accidental intravenous infusion of a large dose of magnesium sulphate during labor: A case report

    Directory of Open Access Journals (Sweden)

    Kamal Kumar

    2013-01-01

    Full Text Available During labor and child delivery, a wide range of drugs are administered. Most of these medications are high-alert medications, which can cause significant harm to the patient due to its inadvertent use. Errors could be caused due to unfamiliarity with safe dosage ranges, confusion between similar looking drugs, mislabeling of drugs, equipment misuse, or malfunction and communication errors. We report a case of inadvertent infusion of a large dose of magnesium sulphate in a pregnant woman.

  18. LDRD final report : robust analysis of large-scale combinatorial applications.

    Energy Technology Data Exchange (ETDEWEB)

    Carr, Robert D.; Morrison, Todd (University of Colorado, Denver, CO); Hart, William Eugene; Benavides, Nicolas L. (Santa Clara University, Santa Clara, CA); Greenberg, Harvey J. (University of Colorado, Denver, CO); Watson, Jean-Paul; Phillips, Cynthia Ann

    2007-09-01

    Discrete models of large, complex systems like national infrastructures and complex logistics frameworks naturally incorporate many modeling uncertainties. Consequently, there is a clear need for optimization techniques that can robustly account for risks associated with modeling uncertainties. This report summarizes the progress of the Late-Start LDRD 'Robust Analysis of Largescale Combinatorial Applications'. This project developed new heuristics for solving robust optimization models, and developed new robust optimization models for describing uncertainty scenarios.

  19. Large Complex Odontoma of Mandible in a Young Boy: A Rare and Unusual Case Report

    Directory of Open Access Journals (Sweden)

    G. Siva Prasad Reddy

    2014-01-01

    Full Text Available Odontomas are the most common odontogenic tumors. They are broadly classified in to Compound Odontoma and Complex Odontoma. Among them complex odontoma is a rare tumor. Occasionally this tumor becomes large, causing expansion of bone followed by facial asymmetry. Otherwise these tumors are asymptomatic and are generally diagnosed on radiographic examination. We report a rare case of complex odontoma of mandible in a young boy. The tumor was treated by surgical excision under general anesthesia.

  20. Large complex odontoma of mandible in a young boy: a rare and unusual case report.

    Science.gov (United States)

    Reddy, G Siva Prasad; Reddy, G V; Sidhartha, B; Sriharsha, K; Koshy, John; Sultana, Rehana

    2014-01-01

    Odontomas are the most common odontogenic tumors. They are broadly classified in to Compound Odontoma and Complex Odontoma. Among them complex odontoma is a rare tumor. Occasionally this tumor becomes large, causing expansion of bone followed by facial asymmetry. Otherwise these tumors are asymptomatic and are generally diagnosed on radiographic examination. We report a rare case of complex odontoma of mandible in a young boy. The tumor was treated by surgical excision under general anesthesia.

  1. Cochlear Implantation in Isolated Large Vestibular Aqueduct Syndrome: Report of Three Cases and Literature Review

    OpenAIRE

    Pradhananga,Rabindra; Natarajan, Kiran; Devarasetty, AmarNath; Kameswaran, Mohan

    2015-01-01

    Introduction Large vestibular aqueduct syndrome (LVAS) is characterized by the enlargement of the vestibular aqueduct associated with sensorineural hearing loss. It is the most common radiographically detectable inner ear anomaly in congenital hearing loss. LVAS may occur as an isolated anomaly or in association with other inner ear malformations. Objective To report three cases of isolated LVAS with a focus on preoperative assessment, surgical issues, and short-term postoperative follow-u...

  2. Breast Implant-Associated Anaplastic Large Cell Lymphoma: A Case Report and Literature Review.

    Science.gov (United States)

    Letter, Haley; Rop, Baiywo; Edison, Michele N; Turner, Patricia

    2016-03-26

    Introduction Anaplastic large cell lymphoma is a very rare T-cell lymphoma that has only recently been found to be associated with breast implants. It has been described in the literature mainly in the form of case reports. This article focuses on the imaging characteristics of this rare disease. We hope to increase awareness of breast imagers and referring physicians to improve early detection rates. Case Report We present the case of a 32-year-old female who presented with several weeks of pain and firmness in her right breast. MRI and ultrasound demonstrated a peri-implant fluid collection. Ultrasound-guided aspiration revealed anaplastic large cell lymphoma. The patient was treated with implant removal alone and has now been in remission for 3 years.  Conclusion Anaplastic large cell lymphoma of the breast is a very rare entity that has mainly been described in the literature as case reports. As in the case of our patient, imaging findings can be very non-specific, and it is important for surgeons, breast imagers, and oncologists to be aware of this rare disease to ensure prompt diagnosis.

  3. Developmental gains in visuospatial memory predict gains in mathematics achievement.

    Science.gov (United States)

    Li, Yaoran; Geary, David C

    2013-01-01

    Visuospatial competencies are related to performance in mathematical domains in adulthood, but are not consistently related to mathematics achievement in children. We confirmed the latter for first graders and demonstrated that children who show above average first-to-fifth grade gains in visuospatial memory have an advantage over other children in mathematics. The study involved the assessment of the mathematics and reading achievement of 177 children in kindergarten to fifth grade, inclusive, and their working memory capacity and processing speed in first and fifth grade. Intelligence was assessed in first grade and their second to fourth grade teachers reported on their in-class attentive behavior. Developmental gains in visuospatial memory span (d = 2.4) were larger than gains in the capacity of the central executive (d = 1.6) that in turn were larger than gains in phonological memory span (d = 1.1). First to fifth grade gains in visuospatial memory and in speed of numeral processing predicted end of fifth grade mathematics achievement, as did first grade central executive scores, intelligence, and in-class attentive behavior. The results suggest there are important individual differences in the rate of growth of visuospatial memory during childhood and that these differences become increasingly important for mathematics learning.

  4. Developmental gains in visuospatial memory predict gains in mathematics achievement.

    Directory of Open Access Journals (Sweden)

    Yaoran Li

    Full Text Available Visuospatial competencies are related to performance in mathematical domains in adulthood, but are not consistently related to mathematics achievement in children. We confirmed the latter for first graders and demonstrated that children who show above average first-to-fifth grade gains in visuospatial memory have an advantage over other children in mathematics. The study involved the assessment of the mathematics and reading achievement of 177 children in kindergarten to fifth grade, inclusive, and their working memory capacity and processing speed in first and fifth grade. Intelligence was assessed in first grade and their second to fourth grade teachers reported on their in-class attentive behavior. Developmental gains in visuospatial memory span (d = 2.4 were larger than gains in the capacity of the central executive (d = 1.6 that in turn were larger than gains in phonological memory span (d = 1.1. First to fifth grade gains in visuospatial memory and in speed of numeral processing predicted end of fifth grade mathematics achievement, as did first grade central executive scores, intelligence, and in-class attentive behavior. The results suggest there are important individual differences in the rate of growth of visuospatial memory during childhood and that these differences become increasingly important for mathematics learning.

  5. Parent-Reported Patterns of Loss and Gain in Communication in 1- to 2-Year-Old Children Are Not Unique to Autism Spectrum Disorder

    Science.gov (United States)

    Brignell, Amanda; Williams, Katrina; Prior, Margot; Donath, Susan; Reilly, Sheena; Bavin, Edith L.; Eadie, Patricia; Morgan, Angela T.

    2017-01-01

    We compared loss and gain in communication from 1 to 2 years in children later diagnosed with autism spectrum disorder (n = 41), language impairment (n = 110) and in children with typical language development at 7 years (n = 831). Participants were selected from a prospective population cohort study of child language (the Early Language in…

  6. Digital automatic gain control

    Science.gov (United States)

    Uzdy, Z.

    1980-01-01

    Performance analysis, used to evaluated fitness of several circuits to digital automatic gain control (AGC), indicates that digital integrator employing coherent amplitude detector (CAD) is best device suited for application. Circuit reduces gain error to half that of conventional analog AGC while making it possible to automatically modify response of receiver to match incoming signal conditions.

  7. Clear cell variant of diffuse large B-cell lymphoma: a case report

    Directory of Open Access Journals (Sweden)

    Sahatciu-Meka Vjollca

    2011-05-01

    Full Text Available Abstract Introduction Diffuse large B-cell lymphoma is a diffuse proliferation of large neoplastic B lymphoid cells with a nuclear size equal to or exceeding the normal macrophage nuclei. We report a case of a clear cell variant of diffuse large B-cell lymphoma involving a lymph node in the neck, which was clinically suspected of being metastatic carcinoma. Case presentation A 39-year-old Caucasian ethnic Albanian man from Kosovo presented with a rapidly enlarging lymph node in his neck, but he also disclosed B symptoms and fatigue. A cytological aspirate of the lymph node revealed pleomorphic features. Our patient underwent a cervical lymph node biopsy (large excision. The mass was homogeneously fish-flesh, pale white tissue replacing almost the whole structure of the lymph node. The lymph node biopsy showed a partial alveolar growth pattern, which raised clinical suspicion that it was an epithelial neoplasm. With regard to morphological and phenotypic features, we discovered large nodules in diffuse areas, comprising large cells with slightly irregular nuclei and clear cytoplasm admixed with a few mononuclear cells. In these areas, there was high mitotic activity, and in some areas there were macrophages with tangible bodies. Staining for cytokeratins was negative. These areas had the following phenotypes: cluster designation marker 20 (CD20 positive, B-cell lymphoma (Bcl-2-positive, Bcl-6-, CD5-, CD3-, CD21+ (in alveolar patterns, prostate-specific antigen-negative, human melanoma black marker 45-negative, melanoma marker-negative, cytokeratin-7-negative and multiple myeloma marker 1-positive in about 30% of cells, and exhibited a high proliferation index marker (Ki-67, 80%. Conclusion According to the immunohistochemical findings, we concluded that this patient has a clear cell variant of diffuse large B-cell lymphoma of activated cell type, post-germinal center cell origin. Our patient is undergoing R-CHOP chemotherapy treatment.

  8. Comparing gains and losses.

    Science.gov (United States)

    McGraw, A Peter; Larsen, Jeff T; Kahneman, Daniel; Schkade, David

    2010-10-01

    Loss aversion in choice is commonly assumed to arise from the anticipation that losses have a greater effect on feelings than gains, but evidence for this assumption in research on judged feelings is mixed. We argue that loss aversion is present in judged feelings when people compare gains and losses and assess them on a common scale. But many situations in which people judge and express their feelings lack these features. When judging their feelings about an outcome, people naturally consider a context of similar outcomes for comparison (e.g., they consider losses against other losses). This process permits gains and losses to be normed separately and produces psychological scale units that may not be the same in size or meaning for gains and losses. Our experiments show loss aversion in judged feelings for tasks that encourage gain-loss comparisons, but not tasks that discourage them, particularly those using bipolar scales.

  9. Cassegrain-Antenna Gain Improvement

    Science.gov (United States)

    Galindo, V.; Cha, A. G.; Mittra, R.

    1986-01-01

    Modified antenna feed with dual-shaped subreflectors yields 10-to20-percent improvement in efficiency of existing large-aperture paraboloidal or Cassegrainian antennas. Such offset dual-shaped subreflector (DSS) feed brings gain of existing paraboloid or Cassegrain antennas up to that of reflector antennas of more recent design at cost considerably lower than for reshaping existing reflecting surfaces. Mathematical procedures developed for synthesizing nearly optimum shapes for DSS elements of new feeds.

  10. Outline for Large-Scale System Operations and D and D Report

    Energy Technology Data Exchange (ETDEWEB)

    Heckendorn, F.

    2000-10-12

    The Department of Energy (DOE) has spent many decades using nuclear reactors and large process equipment for scientific research, reactor fuel production, defense weapons production, medical isotope preparation, and other uses. Many of these large facilities require remote handling and remote maintenance equipment and systems for their day-to-day operations and routine maintenance. In addition, many of these facilities have been taken off-line as a result of change in scientific or military interests, facility age, new technology, or many other varied reasons. Some of these unused facilities are undergoing or will soon undergo deactivation and decommissioning (D and D). The goal of this report is to examine the technical, operational, and regulatory requirements for size reduction, decontamination, sorting, and disposal of failed, or no longer needed, process equipment. The tasks commonly found in these efforts are classified as large-scale because of the reach and lift capacity requir ed of the remote handling systems. The D and D of large facilities would typically require devices with the reach required of the remote devices exceeding 2 meters and lift capacity exceeding 100 kg.

  11. Migratory large vessel vasculitis preceding acute myeloid leukemia: a case report.

    Science.gov (United States)

    Chandratilleke, Dinusha; Anantharajah, Anthea; Vicaretti, Mauro; Benson, Warwick; Berglund, Lucinda J

    2017-03-16

    Large vessel vasculitis is a rare disorder usually occurring in the context of the autoimmune conditions of giant cell arteritis and Takayasu's arteritis. Case reports have described large vessel vasculitis occurring in individuals with myelodysplastic syndrome, preceding transformation to acute myeloid leukemia. A 56-year-old Afghanistan-born woman presented with fever, a tender left carotid artery, and raised inflammatory markers. Computed tomography revealed thickening of the wall of her left carotid artery. Her symptoms resolved spontaneously; however, they recurred weeks later on the contralateral side, along with abdominal pain after eating. Further imaging with computed tomography and positron emission tomography demonstrated resolution of her left carotid artery abnormality, but new wall thickening and inflammation in her right carotid artery, abdominal aorta, and superior mesenteric artery. She was diagnosed as having large vessel vasculitis, which resolved with corticosteroids and methotrexate. Five months later, she developed acute myeloid leukemia. She had no known history of myelodysplastic syndrome at the time of diagnosis with vasculitis. Large vessel vasculitis in older individuals presenting with atypical clinical features, such as a migratory pattern of affected vessels, vessel wall tenderness, and marked systemic inflammation, should prompt a search for underlying myelodysplasia. Clinicians should be vigilant for progression to acute myeloid leukemia.

  12. Indoor acoustic gain design

    Science.gov (United States)

    Concha-Abarca, Justo Andres

    2002-11-01

    The design of sound reinforcement systems includes many variables and usually some of these variables are discussed. There are criteria to optimize the performance of the sound reinforcement systems under indoor conditions. The equivalent acoustic distance, the necessary acoustic gain, and the potential acoustic gain are parameters which must be adjusted with respect to the loudspeaker array, electric power and directionality of loudspeakers, the room acoustics conditions, the distance and distribution of the audience, and the type of the original sources. The design and installation of front of the house and monitoring systems have individual criteria. This article is about this criteria and it proposes general considerations for the indoor acoustic gain design.

  13. Large mucinous biliary cystadenoma with "ovarian-like" stroma: A case report

    Institute of Scientific and Technical Information of China (English)

    Mircea Beuran; Mircea Dan Venter; Laura Dumitru

    2006-01-01

    Hepatobiliary cystadenomas are rare tumors that are difficult to diagnose preoperatively. They can reach large sizes that make them real intraoperative "surprises". A 63-year-old woman, presented with a symptomatic huge abdominal cystic mass, underwent complete resection of the mass with safety margins. Histopathological report revealed mucinous hepatic cystadenoma with "ovarianlike" stroma and areas of sclerohyalinization. The differential diagnosis of the large cystic tumors which occupy the right hemiabdomen must include the biliary cystadenoma; the complete resection of the tumor with safety margins avoids local recurrence, and therefore represents the optimal therapy because of the malignant potential of the disease. The postoperative follow-up includes abdominal ultrasound or CT scan and CA 19-9measurement.

  14. Large Ganglion Cyst with Unusual Location on the Back-A Case Report

    DEFF Research Database (Denmark)

    Schoellhammer, Liv; Nielsen, Thomas Wagner; Berg, Jais Oliver

    2016-01-01

    A ganglion cyst is a soft tissue tumor-like lesion filled with colloid material commonly located on the hand and wrist. We report a case of a large ganglion cyst with an unusual location on the back. The patient presented with a mass growing over 2 months measuring 11.2 × 4.7 × 7.2 cm on magnetic...... resonance imaging. Ultrasound and puncture was attempted twice without achieving drainage. After surgical removal, histologic examination diagnosed the tumor as a ganglion cyst. We conclude that when evaluating a subcutaneous soft tissue mass, regardless of localization, a ganglion cyst may...

  15. Weight gain - unintentional

    Science.gov (United States)

    ... be due to menstruation, heart or kidney failure, preeclampsia, or medicines you take. A rapid weight gain ... al. Position of the American Dietetic Association: weight management. J Am Diet Assoc . 2009;109:330-46. ...

  16. Cochlear Implantation in Isolated Large Vestibular Aqueduct Syndrome: Report of Three Cases and Literature Review

    Directory of Open Access Journals (Sweden)

    Pradhananga, Rabindra

    2014-11-01

    Full Text Available Introduction Large vestibular aqueduct syndrome (LVAS is characterized by the enlargement of the vestibular aqueduct associated with sensorineural hearing loss. It is the most common radiographically detectable inner ear anomaly in congenital hearing loss. LVAS may occur as an isolated anomaly or in association with other inner ear malformations. Objective To report three cases of isolated LVAS with a focus on preoperative assessment, surgical issues, and short-term postoperative follow-up with preliminary auditory habilitation outcomes. Resumed Report One girl and two boys with LVAS were assessed and cochlear implantation was performed for each. Various ways of intraoperative management of cerebrospinal fluid gusher and postoperative care and outcomes are reported. Conclusion Cochlear implantation in the deaf children with LVAS is feasible and effective.

  17. Operation and control of large wind turbines and wind farms. Final report

    DEFF Research Database (Denmark)

    Sørensen, Poul Ejnar; Hansen, Anca Daniela; Thomsen, Kenneth;

    2005-01-01

    This report is the final report of a Danish research project “Operation and control of large wind turbines and wind farms”. The objective of the project has been to analyse and assess operational strategies and possibilities for control of different typesof wind turbines and different wind farm...... concepts. The potentials of optimising the lifetime/energy production ratio by means of using revised operational strategies for the individual wind turbines are investigated. Different strategies have beensimulated, where the power production is decreased to an optimum when taking loads and actual price...... good power quality and limit mechanical loads and life time consumption. The projectdeveloped models for 3 different concepts for wind farms. Two of the concepts use active stall controlled wind turbines, one with AC connection and one with modern HVDC/VSC connection of the wind farm. The third concept...

  18. Large intradural craniospinal arachnoid cyst: A case report and review of literature

    Directory of Open Access Journals (Sweden)

    Souvagya Panigrahi

    2012-01-01

    Full Text Available Presence of an arachnoid cyst at craniospinal junction is not very common. This is a very rare anatomic site, with only seven other cases reported in the literature. We report a case of large intradural craniospinal arachnoid cyst presenting with obstructive hydrocephalus and cranial nerve palsy. A 39-year-old male presented with 8-month history of neck pain, headache, vomiting, visual disturbances, diminished taste sensation, and numbness of face. He had bilateral papilledema on ophthalmoscopy. Magnetic resonance imaging (MRI revealed a posterior fossa arachnoid cyst extending down to the lower border of C5 vertebra. Posterior decompression was done through C5 laminectomy. He made a full recovery and was asymptomatic at 6-month follow-up examination. The clinical features, diagnosis, and management of these rare craniospinal arachnoid cysts are discussed.

  19. Robotic repair of a large abdominal intercostal hernia: a case report and review of literature.

    Science.gov (United States)

    Wang, Stephani C; Singh, Tejinder P

    2017-06-01

    Abdominal intercostal hernia is an uncommon phenomenon, reported in few case reports and small case series. If left untreated, it can lead to strangulation and visceral ischemia. Prompt diagnosis and appropriate surgical intervention are thus critical to prevent resulting morbidity. We present a 50-year-old woman with a large abdominal intercostal hernia after an open nephrectomy. She underwent a successful robotic repair of the hernia with mesh placement. Through the presentation, we would like to raise awareness of intercostal hernia as a complication of open nephrectomy and significance of early diagnosis in avoiding potential morbidity. We also performed a review of literature especially focusing on acquired abdominal intercostal hernia secondary to prior surgery. Although intercostal hernias can be difficult to repair secondary to the size and location, adequate visualization and surgical planning are critical to successful repair.

  20. Metamaterials with Gain

    Science.gov (United States)

    Hess, Ortwin

    2012-02-01

    Nanoplasmonic metamaterials are the key to an extreme control of light and allow us to conceive materials with negative or vanishing refractive index. Indeed, metamaterials enable a multitude of exciting and useful applications, such as subwavelength focusing, invisibility cloaking, and ``trapped rainbow'' stopping of light. The realization of these materials has recently advanced from the microwave to the optical regime. However, at optical wavelengths, metamaterials may suffer from high dissipative losses owing to the metallic nature of their constituent nanoplasmonic meta-molecules. It is therefore not surprising that overcoming loss restrictions by gain is currently one of the most important topics in metamaterials' research. At the same time, providing gain on the nanoplasmonic (metamolecular) level opens up exciting new possibilities such as a whole new type of metamaterial nano-laser with a cavity length of about a tenth of the wavelength. The talk gives an overview of the state of the art of gain-enhanced metamaterials. Particular focus will be placed on nano-plasmonic metamaterials (such as double-fishnet metamaterials) with integrated laser dyes as gain medium. The successful compensation of loss by gain is demonstrated on the meta-molecular level. On the basis of a comprehensive, microscopic Maxwell-Bloch Langevin approach of spatio-temporal light amplification and lasing in gain-enhanced nanoplasmonic (negative-index) metamaterials a methodology based on the discrete Poynting's theorem is introduced that allows dynamic tracing of the flow of electromagnetic energy into and out of ``microscopic'' channels (light field, plasmons, gain medium). It is shown that steady-state amplification can be achieved in nanoplasmonic metamaterials. Finally, a complex spatio-temporal interplay of light-field and coherent absorption dynamics is revealed in the lasing dynamics of a nanoplasmonic gain-enhanced double-fishnet metamaterial.

  1. Rating and Classification of Incident Reporting in Radiology in a Large Academic Medical Center.

    Science.gov (United States)

    Mansouri, Mohammad; Aran, Shima; Shaqdan, Khalid W; Abujudeh, Hani H

    2016-01-01

    The purpose of this article is to provide a rate of safety incident report of adverse events in a large academic radiology department and to share the various types that may occur. This is a Health Insurance Portability and Accountability Act compliant, institutional review board-approved study. Consent requirement was waived. All incident reports from April 2006-September 2012 were retrieved. Events were further classified as follows: diagnostic test orders, identity document or documentation or consent, safety or security or conduct, service coordination, surgery or procedure, line or tube, fall, medication or intravenous safety, employee general incident, environment or equipment, adverse drug reaction (ADR), skin or tissue, and diagnosis or treatment. Overall rates and subclassification rates were calculated. There were 10,224 incident reports and 4,324,208 radiology examinations (rate = 0.23%). The highest rates of the incident reports were due to diagnostic test orders (34.3%; 3509/10,224), followed by service coordination (12.2%; 1248/10,224) and ADR (10.3%; 1052/4,324,208). The rate of incident reporting was highest in inpatient (0.30%; 2949/970,622), followed by emergency radiology (0.22%; 1500/672,958) and outpatient (0.18%; 4957/2,680,628). Approximately 48.5% (4947/10,202) of incidents had no patient harm and did not affect the patient, followed by no patient harm, but did affect the patient (35.2%, 3589/10,202), temporary or minor patient harm (15.5%, 1584/10,202), permanent or major patient harm (0.6%, 62/10,202), and patient death (0.2%, 20/10,202). Within an academic radiology department, the rate of incident reports was only 0.23%, usually did not harm the patient, and occurred at higher rates in inpatients. The most common incident type was in the category of diagnostic test orders, followed by service coordination, and ADRs.

  2. Hypercholesterolemia Induced by a PCSK9 Gain-of-Function Mutation Augments Angiotensin II-Induced Abdominal Aortic Aneurysms in C57BL/6 Mice-Brief Report.

    Science.gov (United States)

    Lu, Hong; Howatt, Deborah A; Balakrishnan, Anju; Graham, Mark J; Mullick, Adam E; Daugherty, Alan

    2016-09-01

    Gain-of-function mutations of PCSK9 (proprotein convertase subtilisin/kexin type 9) lead to hypercholesterolemia. This study was to determine whether infection of normocholesterolemic mice with an adeno-associated viral (AAV) vector expressing a gain-of-function mutation of mouse PCSK9 increased angiotensin II (AngII)-induced abdominal aortic aneurysms. In an initial study, male C57BL/6 mice were injected intraperitoneally with either an empty vector or PCSK9 gain-of-function mutation (D377Y). AAV at 3 doses and fed a saturated fat-enriched diet for 6 weeks. Two weeks after AAV injection, mice were infused with AngII for 4 weeks. Plasma PCSK9 concentrations were increased dose dependently in mice injected with AAV containing PCSK9D377Y mutation and positively associated with elevations of plasma cholesterol concentrations. Infection with intermediate and high doses of PCSK9D377Y.AAV led to equivalent increases of maximal width of abdominal aortas in C57BL/6 mice infused with AngII. Therefore, the intermediate dose was used in subsequent experiments. We then determined effects of PCSK9D377Y.AAV infection on 5 normolipidemic mouse strains, demonstrating that C57BL/6 mice were the most susceptible to this AAV infection. PCSK9D377Y.AAV infected male C57BL/6 mice were also compared with age-matched male low-density lipoprotein receptor(-/-) mice. Although plasma cholesterol concentrations were lower in mice infected with PCSK9D377Y.AAV, these mice had equivalent abdominal aortic aneurysmal formation, compared to low-density lipoprotein receptor(-/-) mice. In a separate study, reduced plasma PCSK9 concentrations by PCSK9 antisense oligonucleotides in male low-density lipoprotein receptor(-/-) mice did not influence AngII-induced abdominal aortic aneurysms. AAV-mediated infection with a mouse PCSK9 gain-of-function mutation is a rapid, easy, and efficient approach for inducing hypercholesterolemia and promoting abdominal aortic aneurysms in C57BL/6 mice infused with Ang

  3. Gain of harmonic generation in high gain free electron laser

    Institute of Scientific and Technical Information of China (English)

    DENG Hai-Xiao; DAI Zhi-Min

    2008-01-01

    In a planar undulator employed free electron laser(FEL),each harmonic radiation starts from linear amplification and ends with nonlinear harmonic interactions of the lower nonlinear harmonics and the fundamental radiation.In this paper,we investigate the harmonic generation based on the dispersion relation driven from the coupled Maxwell-Vlasov equations,taking into account the effects due to energy spread,emittance,betatron oscillation of electron beam as well as diffraction guiding of the radiation field.A 3D universal scaling function for gain of the linear harmonic generation and a 1D universal scaling function for gain of the nonlinear harmonic generation are presented,which promise rapid computation in FEL design and optimization.The analytical approaches have been validated by 3D simulation results in large range.

  4. A report of left dorsal displacement of the large colon in a tropical horse

    Directory of Open Access Journals (Sweden)

    Farhang Sasani

    2013-04-01

    Full Text Available We report one such case which was diagnosed intraoperatively as left dorsal colon volvulus due to multiple mesenteric abnormalities. A 17-year-old castrated male horse was taken to the Tehran University Veterinary Hospital for treatment of metacarpal wound accompanied by severe abdominal distension and acute colic. The treatment and measurement were taken for a month, and the prepared biopsy indicated that the healing trend was obvious. Unfortunately, prior to discharge, the clinical colic manifestations emerged and the animal suddenly died. Dilated large intestine was palpated per rectum and a ventral midline exploratory laparotomy was performed, a complete volvulus of the ascending colon was identified with multiple mesenteric anomalies of unknown aetiology. The pathologic changes observed in this study accurately reflect those changes reported in horse with naturally occurring colonic volvulus and can serve as a reference for subsequent studies on attenuating bowel injury. The present study results can be used to make a scientific assessment of prognosis in the pre-operative, operative, and post-operative management of horses with large colon volvulus.

  5. A report of left dorsal displacement of the large colon in a tropical horse

    Institute of Scientific and Technical Information of China (English)

    Farhang; Sasani; Javad; Javanbakht; Mehdi; Ghamsari; Mehdi; Aghamohammad; Hassan

    2013-01-01

    We report one such case which was diagnosed intraoperatively as left dorsal colon volvulus due to multiple mesenteric abnormalities.A 17-year-old castrated male horse was taken to the Tehran University Veterinary Hospital for treatment of metacarpal wound accompanied by severe abdominal distension and acute colic.The treatment and measurement were taken for a month,and the prepared biopsy indicated that the healing trend was obvious.Unfortunately,prior to discharge,the clinical colic manifestations emerged and the animal suddenly died.Dilated large intestine was palpated per rectum and a ventral midline exploratory laparotomy was performed,a complete volvulus of the ascending colon was identified with multiple mesenteric anomalies of unknown aetiology.The pathologic changes observed in this study accurately reflect those changes reported in horse with naturally occurring colonic volvulus and can serve as a reference for subsequent studies on attenuating bowel injury.The present study results can be used to make a scientific assessment of prognosis in the pre-operative,operative,and post-operative management of horses with large colon volvulus.

  6. A report of left dorsal displacement of the large colon in a tropical horse

    Institute of Scientific and Technical Information of China (English)

    Farhang Sasani; Javad Javanbakht; Mehdi Ghamsari; Mehdi Aghamohammad Hassan

    2013-01-01

    We report one such case which was diagnosed intraoperatively as left dorsal colon volvulus due to multiple mesenteric abnormalities. A 17-year-old castrated male horse was taken to the Tehran University Veterinary Hospital for treatment of metacarpal wound accompanied by severe abdominal distension and acute colic. The treatment and measurement were taken for a month, and the prepared biopsy indicated that the healing trend was obvious. Unfortunately, prior to discharge, the clinical colic manifestations emerged and the animal suddenly died. Dilated large intestine was palpated per rectum and a ventral midline exploratory laparotomy was performed, a complete volvulus of the ascending colon was identified with multiple mesenteric anomalies of unknown aetiology. The pathologic changes observed in this study accurately reflect those changes reported in horse with naturally occurring colonic volvulus and can serve as a reference for subsequent studies on attenuating bowel injury. The present study results can be used to make a scientific assessment of prognosis in the pre-operative, operative, and post-operative management of horses with large colon volvulus.

  7. First Reported Case of Fatal Stinging by the Large Carpenter Bee Xylocopa tranquebarica.

    Science.gov (United States)

    Kularatne, Senanayake A M; Raveendran, Sathasivam; Edirisinghe, Jayanthi; Karunaratne, Inoka; Weerakoon, Kosala

    2016-06-01

    In the order Hymenoptera, bees, hornets, and wasps are well-known stinging insects whose envenoming can be fatal. Their stinging attacks are common in rural and forested areas of Sri Lanka. However, fatal stinging by the large-bodied carpenter bees is unreported. We report the first known case of a fatal sting by the large carpenter bee, Xylocopa tranquebarica, in a forested area in Puttalam (North Western Province) in the dry zone of Sri Lanka. A 59-year-old healthy male manual laborer accompanied by a fellow worker had been fixing a fence on a coconut estate bordering a forested area when a flying insect emerged from a dead tree trunk and stung him on his face. His coworker, who was watching the incident, killed the insect. The victim complained of immediate intense pain in the face and collapsed on the ground just after resuming work after 10 minutes of resting. He was found dead on admission to the hospital 90 minutes later. Autopsy showed normal coronary arteries and heart, but the lungs were slightly congested and contained secretions in the bronchi. Acute anaphylaxis was the most likely cause of death. This case presents the habitat, morphology, attack pattern, and the medical importance of large carpenter bees.

  8. Atypical aleukemic presentation of large granular lymphocytic leukemia: a case report

    Directory of Open Access Journals (Sweden)

    Bagacean C

    2016-12-01

    Full Text Available Cristina Bagacean,1,2 Adrian Tempescul,3 Mariana Patiu,1,4 Bogdan Fetica,4 Horia Bumbea,5,* Mihnea Zdrenghea1,4,* 1Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; 2Laboratory of Immunology and Immunotherapy, University Hospital Brest, 3Department of Hematology, Institute of Cancerology and Hematology, Brest University Medical School, Brest, France; 4Department of Hematology, Ion Chiricuta Oncology Institute, Cluj-Napoca, 5Department of Hematology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania *These authors contributed equally to this work Abstract: Large granular lymphocytic leukemia (LGLL is a rare lymphoproliferative disorder of transformed natural killer or T-cells attributed to chronic exposure to the proinflammatory cytokine IL-15. Diagnosis of the majority of T-cell LGLL is established by documenting clonal large granular lymphocytes (LGLs in peripheral blood, by morphology and immunophenotype. The proteasome inhibitor bortezomib is known to target molecular pathways downstream of the IL-15 receptor signaling and has been proposed as a therapy in these patients. We report an uncommon presentation of LGLL with chronic neutropenia lacking typical blood LGLs, which failed to respond to bortezomib but obtained a very good partial remission with a classical methotrexate regimen. Keywords: large granular lymphocytes, lymphoproliferative, Felty, neutropenia, bortezomib

  9. Theoretical discussion on gain guided and index antiguided fiber laser by variational gain saturation factor

    Science.gov (United States)

    Wang, X.; Xiong, C.; Luo, J.

    2011-03-01

    The variational gain saturation factor was suggested for the theoretical model of side pumping gain guided and index antiguided fiber laser, because of the invalid definition of constant saturation power owing to the large scale core area on the cross section. The variational gain saturation factor was defined by an integral formula and obtained by a numerical method. By this approach, the theoretical model of the side pump gain guided and index antiguided fiber laser was analyzed as regards the influence of output laser power by the index step and gain coefficient.

  10. A large-scale dataset of solar event reports from automated feature recognition modules

    Science.gov (United States)

    Schuh, Michael A.; Angryk, Rafal A.; Martens, Petrus C.

    2016-05-01

    The massive repository of images of the Sun captured by the Solar Dynamics Observatory (SDO) mission has ushered in the era of Big Data for Solar Physics. In this work, we investigate the entire public collection of events reported to the Heliophysics Event Knowledgebase (HEK) from automated solar feature recognition modules operated by the SDO Feature Finding Team (FFT). With the SDO mission recently surpassing five years of operations, and over 280,000 event reports for seven types of solar phenomena, we present the broadest and most comprehensive large-scale dataset of the SDO FFT modules to date. We also present numerous statistics on these modules, providing valuable contextual information for better understanding and validating of the individual event reports and the entire dataset as a whole. After extensive data cleaning through exploratory data analysis, we highlight several opportunities for knowledge discovery from data (KDD). Through these important prerequisite analyses presented here, the results of KDD from Solar Big Data will be overall more reliable and better understood. As the SDO mission remains operational over the coming years, these datasets will continue to grow in size and value. Future versions of this dataset will be analyzed in the general framework established in this work and maintained publicly online for easy access by the community.

  11. A large-scale dataset of solar event reports from automated feature recognition modules

    Directory of Open Access Journals (Sweden)

    Schuh Michael A.

    2016-01-01

    Full Text Available The massive repository of images of the Sun captured by the Solar Dynamics Observatory (SDO mission has ushered in the era of Big Data for Solar Physics. In this work, we investigate the entire public collection of events reported to the Heliophysics Event Knowledgebase (HEK from automated solar feature recognition modules operated by the SDO Feature Finding Team (FFT. With the SDO mission recently surpassing five years of operations, and over 280,000 event reports for seven types of solar phenomena, we present the broadest and most comprehensive large-scale dataset of the SDO FFT modules to date. We also present numerous statistics on these modules, providing valuable contextual information for better understanding and validating of the individual event reports and the entire dataset as a whole. After extensive data cleaning through exploratory data analysis, we highlight several opportunities for knowledge discovery from data (KDD. Through these important prerequisite analyses presented here, the results of KDD from Solar Big Data will be overall more reliable and better understood. As the SDO mission remains operational over the coming years, these datasets will continue to grow in size and value. Future versions of this dataset will be analyzed in the general framework established in this work and maintained publicly online for easy access by the community.

  12. A Large Rice Body-Containing Cyst Mimicking Infection following Total Hip Arthroplasty: A Case Report

    Directory of Open Access Journals (Sweden)

    Wael Bayoud

    2017-01-01

    Full Text Available Introduction. Soft tissue mass following total hip arthroplasty raises several differential diagnoses not limited to infection, hematoma, wear debris, malignancy, and bursitis. Rice body formation in the hip region is an uncommon process denoting a chronic inflammation. We report here the second case of its kind in the medical literature of a wide symptomatic rice-like body cyst complicating a total hip arthroplasty. Case Presentation. This is the case of an 82-year-old white female, presenting with a warm, red, and inflated groin five years after revision of right total hip arthroplasty. Surgical intervention reveals a large well circumscribed cyst containing well-organized rice-like bodies. This eventuality was never reported in differential diagnosis of hip periprosthetic soft tissue masses before. Conclusion. This case report helps widening the array of the differential diagnosis in patients presenting with a slow growing soft tissue mass following total hip arthroplasty, making rice-like bodies cyst a valid one to consider.

  13. Self-Reported Health Symptoms and Conditions Among Complementary and Alternative Medicine Users in a Large Military Cohort

    Science.gov (United States)

    2009-09-01

    Naval Health Research Center Self-reported Health Symptoms and Conditions Among Complementary and Alternative Medicine Users in A Large...California 92106 Self-Reported Health Symptoms and Conditions Among Complementary and Alternative Medicine Users in a Large Military Cohort ISABEL G...symptom and condition reporting in relation to complementary and alternative medicine (CAM) use among members of the US military. METHODS: CAM was

  14. Relational Information Gain

    DEFF Research Database (Denmark)

    Lippi, Marco; Jaeger, Manfred; Frasconi, Paolo

    2011-01-01

    We introduce relational information gain, a refinement scoring function measuring the informativeness of newly introduced variables. The gain can be interpreted as a conditional entropy in a well-defined sense and can be efficiently approximately computed. In conjunction with simple greedy general......-to-specific search algorithms such as FOIL, it yields an efficient and competitive algorithm in terms of predictive accuracy and compactness of the learned theory. In conjunction with the decision tree learner TILDE, it offers a beneficial alternative to lookahead, achieving similar performance while significantly...

  15. Placement of endosseous implant in infected alveolar socket with large fenestration defect: A comparative case report

    Directory of Open Access Journals (Sweden)

    Balaji Anitha

    2010-01-01

    Full Text Available Placement of endosseous implants into infected bone is often deferred or avoided due to fear of failure. However, with the development of guided bone regeneration [GBR], some implantologists have reported successful implant placement in infected sockets, even those with fenestration defects. We had the opportunity to compare the osseointegration of an immediate implant placed in an infected site associated with a large buccal fenestration created by the removal of a root stump with that of a delayed implant placed 5 years after extraction. Both implants were placed in the same patient, in the same dental quadrant by the same implantologist. GBR was used with the fenestration defect being filled with demineralized bone graftFNx01 and covered with collagen membraneFNx08. Both implants were osseointegrated and functional when followed up after 12 months.

  16. MRI findings of a large pedunculated eccrine poroma: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seung Hyun; Ryu, Jeong Ah; Lee, Jung Il; Pyo, Ju Yeon; Oh, Young Ha [Dept. of ,Hanyang University Guri Hospital, Guri (Korea, Republic of); Lee, Chul Min [Dept. of Radiology, Hanyang University Hospital, Seoul (Korea, Republic of)

    2016-02-15

    Eccrine poroma is a rare benign neoplasm of the eccrine sweat gland that usually presents as a small skin lesion such as a papule or nodule. This benign tumor has an overall good prognosis; however, eccrine porocarcinomas can arise from long-standing pre-existing benign eccrine poromas. We reported the case of a 37-year-old man with mental retardation who presented with an 8-cm pedunculated and densely pigmented eccrine poroma on the left hip. The tumor showed low signal intensity on T1-weighted MRI, with inhomogenously high signal intensity on T2-weighted images and strong contrast enhancement after intravenous gadolinium administration. It directly extended from the dermal layer, and the subcutaneous tissue was preserved. Radiologists should be aware that eccrine poromas could be large and pedunculated. Furthermore, related MRI findings and diagnostic clues should be carefully considered.

  17. Final report LDRD project 105816 : model reduction of large dynamic systems with localized nonlinearities.

    Energy Technology Data Exchange (ETDEWEB)

    Lehoucq, Richard B.; Segalman, Daniel Joseph; Hetmaniuk, Ulrich L. (University of Washington, Seattle, WA); Dohrmann, Clark R.

    2009-10-01

    Advanced computing hardware and software written to exploit massively parallel architectures greatly facilitate the computation of extremely large problems. On the other hand, these tools, though enabling higher fidelity models, have often resulted in much longer run-times and turn-around-times in providing answers to engineering problems. The impediments include smaller elements and consequently smaller time steps, much larger systems of equations to solve, and the inclusion of nonlinearities that had been ignored in days when lower fidelity models were the norm. The research effort reported focuses on the accelerating the analysis process for structural dynamics though combinations of model reduction and mitigation of some factors that lead to over-meshing.

  18. Differentiating a large abdominal cystic lymphangioma from multicystic mesothelioma: report of a case.

    Science.gov (United States)

    Nagata, Hiroshi; Yonemura, Yutaka; Canbay, Emel; Ishibashi, Haruaki; Narita, Makoto; Mike, Makio; Kano, Nobuyasu

    2014-07-01

    We report a case of retroperitoneal cystic lymphangioma in a 30-year-old woman who presented with abdominal distention and pain. Imaging studies revealed a large, thin-walled multicystic mass occupying the whole abdomen. Based on a preoperative diagnosis of multicystic mesothelioma, we performed laparotomy, which revealed a tumor arising from the gastropancreatic ligament in the posterior wall of the omental bursa. We resected the tumor completely, without the adjacent viscera. The final pathological diagnosis was cystic lymphangioma, based on the immunohistochemical findings of positive CD31 and CD34 expression, the presence of smooth muscle confirmed by smooth muscle antigen and desmin, and negative calretinin, WT-1 and cytokeratins 5/6 expression. Multicystic mesotheliomas and cystic lymphangiomas are so similar in morphology that immunohistochemical staining should be fully utilized to differentiate them.

  19. Two-Stage Surgery for a Large Cervical Dumbbell Tumour in Neurofibromatosis 1: A Case Report

    Directory of Open Access Journals (Sweden)

    Mohd Ariff S

    2011-11-01

    Full Text Available Spinal neurofibromas occur sporadically and typically occur in association with neurofibromatosis 1. Patients afflicted with neurofibromatosis 1 usually present with involvement of several nerve roots. This report describes the case of a 14- year-old child with a large intraspinal, but extradural tumour with paraspinal extension, dumbbell neurofibroma of the cervical region extending from the C2 to C4 vertebrae. The lesions were readily detected by MR imaging and were successfully resected in a two-stage surgery. The time interval between the first and second surgery was one month. We provide a brief review of the literature regarding various surgical approaches, emphasising the utility of anterior and posterior approaches.

  20. Large-Grain Superconducting Gun Cavity Testing Program Phase One Closing Report

    Energy Technology Data Exchange (ETDEWEB)

    Hammons, L. [Brookhaven National Lab. (BNL), Upton, NY (United States); Bellavia, S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Belomestnykh, S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Ben-Zvi, I. [Brookhaven National Lab. (BNL), Upton, NY (United States); Cullen, C. [Brookhaven National Lab. (BNL), Upton, NY (United States); Dai, J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Degen, C. [Brookhaven National Lab. (BNL), Upton, NY (United States); Hahn, H. [Brookhaven National Lab. (BNL), Upton, NY (United States); Masi, L. [Brookhaven National Lab. (BNL), Upton, NY (United States); McIntyre, G. [Brookhaven National Lab. (BNL), Upton, NY (United States); Schultheiss, C. [Brookhaven National Lab. (BNL), Upton, NY (United States); Seda, T. [Brookhaven National Lab. (BNL), Upton, NY (United States); Kellerman, R. [Brookhaven National Lab. (BNL), Upton, NY (United States); Tallerico, T. [Brookhaven National Lab. (BNL), Upton, NY (United States); Todd, R. [Brookhaven National Lab. (BNL), Upton, NY (United States); Tuozzolo, S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Xu, W. [Brookhaven National Lab. (BNL), Upton, NY (United States); Than, Y. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2013-10-31

    This report details the experimental configuration and RF testing results for the first phase of a large-grained niobium electron gun cavity testing program being conducted in the Small Vertical Testing Facility in the Collider-Accelerator Department. This testing is meant to explore multi-pacting in the cavity and shed light on the behavior of a counterpart cavity of identical geometry installed in the Energy Recovery LINAC being constructed in the Collider-Accelerator Department at Brookhaven National Laboratory. This test found that the Q of the large-grained cavity at 4 K reached ~6.5 × 108 and at 2 K reached a value of ~6 × 109. Both of these values are about a factor of 10 lower than would be expected for this type of cavity given the calculated surface resistance and the estimated geometry factor for this half-cell cavity. In addition, the cavity reached a peak voltage of 0.6 MV before there was sig-nificant decline in the Q value and a substantial increase in field emission. This relatively low volt-age, coupled with the low Q and considerable field emission suggest contamination of the cavity interior, possibly during experimental assembly. The results may also suggest that additional chemical etching of the interior surface of the cavity may be beneficial. Throughout the course of testing, various challenges arose including slow helium transfer to the cryostat and cable difficulties. These difficulties and others were eventually resolved, and the re-port discusses the operating experience of the experiment thus far and the plans for future work aimed at exploring the nature of multipacting with a copper cathode inserted into the cavity.

  1. Large cavernous hemangioma of the adrenal gland: Laparoscopic treatment. Report of a case.

    Science.gov (United States)

    Agrusa, A; Romano, G; Salamone, G; Orlando, E; Di Buono, G; Chianetta, D; Sorce, V; Gulotta, L; Galia, M; Gulotta, G

    2015-01-01

    Cavernous hemangioma of the adrenal gland is a rare benign tumor. The diagnosis is often postoperative on histological exam with the presence of blood-filled, dilated vascular spaces. We report the clinical case of a 49 years-old woman who came to our observation with aspecific abdominal pain. A computed tomography (CT) abdominal scan revealed a 11cm right adrenal mass. This lesion was well circumscribed, round, encapsulated. After iodinated-contrast we observed a progressive, inhomogeneous enhancement without evidence of active bleeding and with pre-operative diagnosis of adrenal hemangioma. Laparoscopic adrenalectomy was performed by a transperitoneal flank approach. Pathological examination revealed a 11cm adrenal mass with extensive central necrotic areas mixed to sinusoidal dilation and fibrotic septa. Postoperative diagnosis was adrenal hemangioma. Adrenal hemangiomas occur infrequently. Generally these adrenal masses are non-functioning and there is no specific symptoms. Recent records demonstrate that laparoscopic adrenalectomy is technically safe and feasible for large adrenal tumors, but controversy exists in cases of suspected malignancy. We choose laparoscopic approach to adrenal gland on the basis of preoperative CT abdominal scan that excludes radiological signs of adrenocortical carcinoma (ACC) such as peri-adrenal infiltration and vascular invasion. Laparoscopic adrenalectomy is considered the standard treatment in case of diagnosis of benign lesions. In this case report we discussed a large adrenal cavernous hemangioma treated with laparoscopic approach. Fundamental is the study of preoperative endocrine disorders and radiologic findings to exclude signs of malignancy. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  2. Large-volume liposuction and prevention of type 2 diabetes: a preliminary report.

    Science.gov (United States)

    Narsete, Thomas; Narsete, Michele; Buckspan, Randy; Ersek, Robert

    2012-04-01

    This report presents a preliminary study investigating the effects of large-volume liposuction on the parameters that determine type 2 diabetes. The study enrolled 31 patients with a body mass index (BMI) exceeding 30 kg/m(2) over a 1-year period. All the liposuction procedures were performed with the patient under local anesthesia using ketamine/valium sedation. Pre- and postoperative blood pressure, fasting glucose, glycosylated hemoglobin (HbA1C), weight, and BMI were evaluated for 16 of the 30 patients who returned for a follow-up visit 3 to 12 months postoperatively. The average aspirate was 8,455 ml without dermolipectomy and 5,795 ml with dermolipectomy. The data reveal a trend of improvement in blood sugar levels associated with weight loss that helps the patients. The average blood sugar level dropped 18% in our return patients, and the average weight loss was 9.2%. The average drop in BMI was 6.2%, and HbA1C showed a decrease of 2.3%. The patients with the best weight loss had the best reduction in blood sugar level and blood pressure. No transfers to the hospital and no thromboebolism occurred for any of the 31 patients. One dehiscence, two wound infections, and three seromas were reported. The authors hypothesize that large-volume liposuction in their series may have motivated some to diet, which could be explored in a larger series with control groups. Liposuction alone did not improve obesity but helped to motivate some of the patients to lose weight. These patients had the best results.

  3. Exploratory factor analysis of self-reported symptoms in a large, population-based military cohort

    Directory of Open Access Journals (Sweden)

    Bliese Paul D

    2010-10-01

    Full Text Available Abstract Background US military engagements have consistently raised concern over the array of health outcomes experienced by service members postdeployment. Exploratory factor analysis has been used in studies of 1991 Gulf War-related illnesses, and may increase understanding of symptoms and health outcomes associated with current military conflicts in Iraq and Afghanistan. The objective of this study was to use exploratory factor analysis to describe the correlations among numerous physical and psychological symptoms in terms of a smaller number of unobserved variables or factors. Methods The Millennium Cohort Study collects extensive self-reported health data from a large, population-based military cohort, providing a unique opportunity to investigate the interrelationships of numerous physical and psychological symptoms among US military personnel. This study used data from the Millennium Cohort Study, a large, population-based military cohort. Exploratory factor analysis was used to examine the covariance structure of symptoms reported by approximately 50,000 cohort members during 2004-2006. Analyses incorporated 89 symptoms, including responses to several validated instruments embedded in the questionnaire. Techniques accommodated the categorical and sometimes incomplete nature of the survey data. Results A 14-factor model accounted for 60 percent of the total variance in symptoms data and included factors related to several physical, psychological, and behavioral constructs. A notable finding was that many factors appeared to load in accordance with symptom co-location within the survey instrument, highlighting the difficulty in disassociating the effects of question content, location, and response format on factor structure. Conclusions This study demonstrates the potential strengths and weaknesses of exploratory factor analysis to heighten understanding of the complex associations among symptoms. Further research is needed to

  4. ParaText : scalable solutions for processing and searching very large document collections : final LDRD report.

    Energy Technology Data Exchange (ETDEWEB)

    Crossno, Patricia Joyce; Dunlavy, Daniel M.; Stanton, Eric T.; Shead, Timothy M.

    2010-09-01

    This report is a summary of the accomplishments of the 'Scalable Solutions for Processing and Searching Very Large Document Collections' LDRD, which ran from FY08 through FY10. Our goal was to investigate scalable text analysis; specifically, methods for information retrieval and visualization that could scale to extremely large document collections. Towards that end, we designed, implemented, and demonstrated a scalable framework for text analysis - ParaText - as a major project deliverable. Further, we demonstrated the benefits of using visual analysis in text analysis algorithm development, improved performance of heterogeneous ensemble models in data classification problems, and the advantages of information theoretic methods in user analysis and interpretation in cross language information retrieval. The project involved 5 members of the technical staff and 3 summer interns (including one who worked two summers). It resulted in a total of 14 publications, 3 new software libraries (2 open source and 1 internal to Sandia), several new end-user software applications, and over 20 presentations. Several follow-on projects have already begun or will start in FY11, with additional projects currently in proposal.

  5. Intravascular Large B-Cell Lymphoma Diagnosed on Prostate Biopsy: A Case Report

    Directory of Open Access Journals (Sweden)

    Nazan Özsan

    2014-12-01

    Full Text Available Intravascular large B-cell lymphoma (IVLBCL is a very rare type of non-Hodgkin lymphoma, usually affecting elderly patients and characterized by selective infiltration of neoplastic cells within blood vessels’ lumina. IVLBCL diagnosed with prostatic involvement is extremely rare. We report a patient of 65 years old, having mostly neurological complaints but diagnosed with IVLBCL upon histopathological examination of transurethral prostate resection material, which revealed large neoplastic cell infiltration totally limited within the lumens of small vessels. By immunohistochemistry, neoplastic cell infiltration was positive with MUM1, bcl-6, and bcl-2 and negative with ALK1, CD10, and CD30, with a high Ki-67 proliferation index. CD34 and CD31 staining showed expression in endothelial cells, highlighting the intravascular nature of neoplastic infiltrate. The patient unfortunately refused to receive treatment and died of the disease 8 months after the diagnosis. IVLBCL, though very rare, should be considered in differential diagnosis of all organ biopsies with intravascular infiltration. Further improvements in the understanding of the pathogenesis and biology of this rare type of lymphoma are mandatory.

  6. Colloids Versus Albumin in Large Volume Paracentesis to Prevent Circulatory Dysfunction: Evidence-based Case Report.

    Science.gov (United States)

    Widjaja, Felix F; Khairan, Paramita; Kamelia, Telly; Hasan, Irsan

    2016-04-01

    Large volume paracentesis may cause paracentesis induced circulatory dysfunction (PICD). Albumin is recommended to prevent this abnormality. Meanwhile, the price of albumin is too expensive and there should be another alternative that may prevent PICD. This report aimed to compare albumin to colloids in preventing PICD. Search strategy was done using PubMed, Scopus, Proquest, dan Academic Health Complete from EBSCO with keywords of "ascites", "albumin", "colloid", "dextran", "hydroxyethyl starch", "gelatin", and "paracentesis induced circulatory dysfunction". Articles was limited to randomized clinical trial and meta-analysis with clinical question of "In hepatic cirrhotic patient undergone large volume paracentesis, whether colloids were similar to albumin to prevent PICD". We found one meta-analysis and four randomized clinical trials (RCT). A meta analysis showed that albumin was still superior of which odds ratio 0.34 (0.23-0.51). Three RCTs showed the same results and one RCT showed albumin was not superior than colloids. We conclude that colloids could not constitute albumin to prevent PICD, but colloids still have a role in patient who undergone paracentesis less than five liters.

  7. Ligation of an unusually large vessel during maxillary sinus floor augmentation. A case report.

    Science.gov (United States)

    Testori, Tiziano; Rosano, Gabriele; Taschieri, Silvio; Del Fabbro, Massimo

    2010-01-01

    The purpose of the present case report was to document a maxillary sinus floor augmentation procedure involving ligation of a blood vessel with a nearly 3-mm diameter in the lateral wall of the maxillary sinus. A bilateral maxillary sinus floor augmentation procedure was performed in a 51-year-old healthy man. The preoperative computed tomography scan revealed a bony canal within the lateral maxillary sinus wall of the right as well as the left side close to the alveolar ridge. A vessel with a diameter of nearly 3 mm was identified during the sinus floor augmentation on the left side. The vessel was exposed and ligated. A vessel with a diameter of approximately 1 mm was identified on the right side and the sinus floor augmentation was performed without ligation. No complications were observed and the postoperative healing was uneventful. Although accidental laceration of vessels with an unusually large diameter during maxillary sinus floor augmentation is not life-threatening, impaired visualisation may compromise the augmentation procedure, including the elevation of the Schneiderian membrane. Moreover, postoperative bleeding and formation of a haematoma may occur. Therefore, ligation of vessels with an unusually large diameter is recommended during maxillary sinus floor augmentation to minimise intra- and postoperative complications.

  8. Model checking methodology for large systems, faults and asynchronous behaviour. SARANA 2011 work report

    Energy Technology Data Exchange (ETDEWEB)

    Lahtinen, J. [VTT Technical Research Centre of Finland, Espoo (Finland); Launiainen, T.; Heljanko, K.; Ropponen, J. [Aalto Univ., Espoo (Finland). Dept. of Information and Computer Science

    2012-07-01

    Digital instrumentation and control (I and C) systems are challenging to verify. They enable complicated control functions, and the state spaces of the models easily become too large for comprehensive verification through traditional methods. Model checking is a formal method that can be used for system verification. A number of efficient model checking systems are available that provide analysis tools to determine automatically whether a given state machine model satisfies the desired safety properties. This report reviews the work performed in the Safety Evaluation and Reliability Analysis of Nuclear Automation (SARANA) project in 2011 regarding model checking. We have developed new, more exact modelling methods that are able to capture the behaviour of a system more realistically. In particular, we have developed more detailed fault models depicting the hardware configuration of a system, and methodology to model function-block-based systems asynchronously. In order to improve the usability of our model checking methods, we have developed an algorithm for model checking large modular systems. The algorithm can be used to verify properties of a model that could otherwise not be verified in a straightforward manner. (orig.)

  9. Cost optimizing of large-scale offshore wind farms. Appendix K to Q. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This Volume 4 contains reports prepared by SEAS Distribution A.m.b.A., Risoe National Laboratory, Nellemann, Nielsen and Rauschenberger A/S (NNR), Universidad Politecnica de Madrid, National Wind Power Ltd. and Stadtwerke Rostock AG. Appendix K - Wind and wave measurements; Appendix L - Establishment of design basis (wind, wave and ice loads). Appendix M - Wake effects and wind farm modelling. Appendix N - Functional requirements and optimisation of wind turbines. Appendix O - Operation and maintenance system. Appendix O.1 - Helicopter Service (alternative). Appendix P - Cost optimising of large scale offshore wind farms in UK waters. Appendix Q - Cost optimising of large scale offshore wind farms in German waters. Appendix K, L and N have been prepared by Risoe National Laboratory. Appendix M has been prepared by Universidad Politecnica de Madrid. Appendix 0 has been prepared by SEAS Distribution A.m.b.A.. Appendix O.1 has been prepared by Nellemann, Nielsen and Rauschenberger A/S. Appendix P has been prepared by National Wind Power Ltd.. Appendix Q has been prepared by Stadtwerke Rostock AG. (au)

  10. A large gastrointestinal stromal tumor of the duodenum: a case report

    Directory of Open Access Journals (Sweden)

    Al-Ahmad Firas

    2011-09-01

    Full Text Available Abstract Introduction Gastrointestinal stromal tumors of the duodenum are uncommon. They can reach a large size. Diagnosis can be elusive and managing them can be difficult. Our case report aims to increase awareness and highlight some issues related to the diagnosis and management of duodenal gastrointestinal stromal tumors. Case presentation We present the case of a 38-year-old Middle Eastern woman with a large, slowly-growing gastrointestinal stromal tumor of the duodenum. Her complaints were minor epigastric discomfort and swelling. A pancreaticoduodenectomy with complete tumor excision was performed. She was doing very well with no evidence of disease recurrence when she was last seen 34 months after her operation. Conclusion Gastrointestinal stromal tumors of the duodenum should be suspected in any patient with a duodenal wall mass. Extramural growth and central ulceration with or without bleeding should alert the endoscopist to the possibility of a duodenal gastrointestinal stromal tumor diagnosis. There is more than one surgical approach available; however, complete surgical excision, with negative margins, is the absolute requirement. Preoperative imatinib mesylate can be considered in unresectable or borderline resectable cases.

  11. Successful Treatment of a Large Pelvic Abscess Using Intraluminal VAC: A Case Report.

    Science.gov (United States)

    Aras, Abbas; Celik, Sebahattin; Kiziltan, Remzi; Yilmaz, Özkan; Kotan, Çetin

    2016-04-01

    The most feared complication of the surgical treatment of rectal cancer is anastomotic leakage, which is related to high rates of mortality and morbidity. Here, we present a patient who could not be treated with surgical drainage but treated by intraluminal Vacuum Associated Closure (VAC). A 34-year-old male patient was treated for rectal cancer by low anterior resection, colorectal anastomosis, and diverting ileostomy following neoadjuvant CRT. The patient reported with a postoperative anastomotic disruption and a large pelvic abscess. Due to the continuation of foul-smell drainage inspite of perianal incision and drainage, intraluminal VAC was applied and the pelvic abscess and the foul-smell were successfully treated. The presence of an adequate anal sphincter tonus is a disadvantage in anastomotic leakage, since it prevents the emptying of the intestinal content and also precludes the drainage of the pelvic abscess. The endoluminal application of VAC, similar to the results of application of VAC in open wounds, has been demonstrated to decrease fibrin and necrotic tissue in the pelvic cavity and increase granulation tissue. VAC, which has long been used in the treatment of open wounds, is a promising method in the treatment of large pelvic abscesses due to anastomotic leakage following rectum resection.

  12. An unusually large myofibroblastoma in a male breast: a case report

    Directory of Open Access Journals (Sweden)

    Abeysekara Abeywardana MS

    2008-05-01

    Full Text Available Abstract Introduction Myofibroblastoma of the breast is a rare benign stromal tumour seen predominantly in men. The gross appearance is that of a well-circumscribed nodule, characteristically small, seldom exceeding 3 cm. We present a case of an unusually large myofibroblastoma, which mimicked a malignant breast tumour. Case presentation A 65-year-old man presented with a rapid enlargement of the right breast over 6 weeks. Examination revealed a firm 15 cm hemispherical lump occupying the whole of the right breast with peau d'orange appearance of the overlying skin and distortion of the nipple. The clinical and radiological features suggested the possibility of sarcoma of the breast. However, a guided Tru-Cut biopsy was inconclusive. A mastectomy was performed to remove the tumour, which weighed more than 2 kg. Histopathology and immunocytochemistry revealed a mixed classical and collagenised type of myofibroblastoma. The patient is well with no evidence of recurrence 5 years after the mastectomy. Conclusion This unexpected presentation of an unusually large myofibroblastoma in a male breast is the largest reported to date. Myofibroblastomas can mimic malignant neoplasms and the clinical significance of this entity lies primarily in its recognition as a distinctive benign neoplasm.

  13. Paul Scherrer Institute Scientific and Technical Report 2000. Volume VI: Large Research Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Foroughi, Fereydoun; Bercher, Renate; Buechli, Carmen; Zumkeller, Lotty [eds.

    2001-07-01

    The PSI Department Large Research Facilities (GFA) joins the efforts to provide an excellent research environment to Swiss and foreign research groups on the experimental facilities driven by our high intensity proton accelerator complex. Its divisions care for the running, maintenance and enhancement of the accelerator complex, the primary proton beamlines, the targets and the secondary beams as well as the neutron spallation source SINQ. The division for technical support and coordination provides for technical support to the research facility complementary to the basic logistic available from the department for logistics and marketing. Besides running the facilities, the staff of the department is also involved in theoretical and experimental research projects. Some of them address basic scientific questions mainly concerning the properties of micro- or nanostructured materials: experiments as well as large scale computer simulations of molecular dynamics were performed to investigate nonclassical materials properties. Others are related to improvements or extensions of the capabilities of our facilities. We also report on intriguing results from applications of the neutron capture radiography, the prompt gamma activation method and the isotope production facility at SINQ.

  14. Intravascular large B-cell lymphoma of the kidney: A case report

    Directory of Open Access Journals (Sweden)

    Jia Nan

    2011-09-01

    Full Text Available Abstract We report a 41-year-old Chinese woman with intravascular large B-cell lymphoma diagnosed by percutaneous renal biopsy. The patient was admitted to Nanfang Hospital of Southern Medical University, Guangzhou, China with complaints of high spiking fever for a month and bilateral lower limb fatigue with difficulty ambulating for the past 5 months. She had renal dysfunction with a total urinary protein of 5.61 g/dL (56.1 g/L, serum albumin of 2.89 g/dL (28.9 g/L, urea nitrogen of 2.24 mg/dL (1.6 mmol/L, and serum creatinine of 0.54 mg/dL (48 μmol/L. Bone marrow biopsy revealed myeloproliferative disorder without abnormal myeloid or lymphocytic proliferation. Positron Emission Tomography-Computed Tomography (PET-CT showed marked bilateral swelling and enlargement of the renal parenchyma with splenic enlargement and involvement of multiple vertebrae. Percutaneous renal biopsy showed island-like accumulations of medium to large lymphoid cells in many areas of the interstitium, with round vesicular nuclei containing distinct basophilic nucleoli. Immunohistochemical analysis together with other supportive investigation confirmed the diagnosis of intravascular large B-cell lymphoma. Ten days later, she was started on chemotherapy with CHOP (cyclophosphamide, doxorubicin, leurocristime and prednisone for a week. Palliative radiotherapy DT 40Gy/20F with other supportive treatment was provided for metastatic foci in the medullary cavity of the sternum, T1-T7. The patient regained muscle strength in both lower limbs and was able to walk again after three weeks. The patient was discharged after hepatic and renal function and proteinuria values had returned to normal. Follow-up data shows the patient to be alive nine months after discharge.

  15. Should I Gain Weight?

    Science.gov (United States)

    ... If you're having trouble with your body image, talk about how you feel with someone you like and trust who's been through it — maybe a parent, doctor, counselor, coach, or teacher. continue It's the Growth, Not the Gain No ...

  16. Collaborative Visualization for Large-Scale Accelerator Electromagnetic Modeling (Final Report)

    Energy Technology Data Exchange (ETDEWEB)

    William J. Schroeder

    2011-11-13

    This report contains the comprehensive summary of the work performed on the SBIR Phase II, Collaborative Visualization for Large-Scale Accelerator Electromagnetic Modeling at Kitware Inc. in collaboration with Stanford Linear Accelerator Center (SLAC). The goal of the work was to develop collaborative visualization tools for large-scale data as illustrated in the figure below. The solutions we proposed address the typical problems faced by geographicallyand organizationally-separated research and engineering teams, who produce large data (either through simulation or experimental measurement) and wish to work together to analyze and understand their data. Because the data is large, we expect that it cannot be easily transported to each team member's work site, and that the visualization server must reside near the data. Further, we also expect that each work site has heterogeneous resources: some with large computing clients, tiled (or large) displays and high bandwidth; others sites as simple as a team member on a laptop computer. Our solution is based on the open-source, widely used ParaView large-data visualization application. We extended this tool to support multiple collaborative clients who may locally visualize data, and then periodically rejoin and synchronize with the group to discuss their findings. Options for managing session control, adding annotation, and defining the visualization pipeline, among others, were incorporated. We also developed and deployed a Web visualization framework based on ParaView that enables the Web browser to act as a participating client in a collaborative session. The ParaView Web Visualization framework leverages various Web technologies including WebGL, JavaScript, Java and Flash to enable interactive 3D visualization over the web using ParaView as the visualization server. We steered the development of this technology by teaming with the SLAC National Accelerator Laboratory. SLAC has a computationally

  17. Large capillary hemangioma of the temporal bone with a dural tail sign: A case report

    KAUST Repository

    YANG, GUANG

    2014-05-13

    The present study reports a rare case of large capillary hemangioma of the temporal bone with a dural tail sign. A 57-year-old female presented with pulsatile tinnitus and episodic vertigo associated with a ten-year history of an intermittent faint headache. Magnetic resonance imaging revealed a mass in the right petrous bone, which was hypointense on T1-weighted images and heterogeneously hyperintense on T2-weighted images, and showed a dural tail sign following gadolinium administration. Pre-operatively, this tumor was believed to be a meningioma. During surgery, the vascular tumor was removed by a modified pterional approach. A histopathological examination indicated that the tumor was a capillary hemangioma. Although intraosseous capillary hemangiomas are rare, they most frequently affect the temporal bone. Hemangiomas of the temporal bone may mimic other more common basal tumors. The diagnosis is most often made during surgical resection. The dural tail sign is not specific for meningioma, as it also occurs in other intracranial or extracranial tumors. The treatment of intratemporal hemangiomas is complete surgical excision, with radiotherapy used for unresectable lesions. To the best of our knowledge, the present study is the fourth case of intraosseous intracranial capillary hemangioma, but the largest intratemporal hemangioma to be reported in the literature to date.

  18. Large capillary hemangioma of the temporal bone with a dural tail sign: A case report.

    Science.gov (United States)

    Yang, Guang; Li, Chenguang; Chen, Xin; Liu, Yaohua; Han, Dayong; Gao, Xin; Kawamoto, Keiji; Zhao, Shiguang

    2014-07-01

    The present study reports a rare case of large capillary hemangioma of the temporal bone with a dural tail sign. A 57-year-old female presented with pulsatile tinnitus and episodic vertigo associated with a ten-year history of an intermittent faint headache. Magnetic resonance imaging revealed a mass in the right petrous bone, which was hypointense on T1-weighted images and heterogeneously hyperintense on T2-weighted images, and showed a dural tail sign following gadolinium administration. Pre-operatively, this tumor was believed to be a meningioma. During surgery, the vascular tumor was removed by a modified pterional approach. A histopathological examination indicated that the tumor was a capillary hemangioma. Although intraosseous capillary hemangiomas are rare, they most frequently affect the temporal bone. Hemangiomas of the temporal bone may mimic other more common basal tumors. The diagnosis is most often made during surgical resection. The dural tail sign is not specific for meningioma, as it also occurs in other intracranial or extracranial tumors. The treatment of intratemporal hemangiomas is complete surgical excision, with radiotherapy used for unresectable lesions. To the best of our knowledge, the present study is the fourth case of intraosseous intracranial capillary hemangioma, but the largest intratemporal hemangioma to be reported in the literature to date.

  19. FutureGen 2.0 Oxy-combustion Large Scale Test – Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Kenison, LaVesta [URS, Pittsburgh, PA (United States); Flanigan, Thomas [URS, Pittsburgh, PA (United States); Hagerty, Gregg [URS, Pittsburgh, PA (United States); Gorrie, James [Air Liquide, Kennesaw, GA (United States); Leclerc, Mathieu [Air Liquide, Kennesaw, GA (United States); Lockwood, Frederick [Air Liquide, Kennesaw, GA (United States); Falla, Lyle [Babcock & Wilcox and Burns McDonnell, Kansas City, MO (United States); Macinnis, Jim [Babcock & Wilcox and Burns McDonnell, Kansas City, MO (United States); Fedak, Mathew [Babcock & Wilcox and Burns McDonnell, Kansas City, MO (United States); Yakle, Jeff [Babcock & Wilcox and Burns McDonnell, Kansas City, MO (United States); Williford, Mark [Futuregen Industrial Alliance, Inc., Morgan County, IL (United States); Wood, Paul [Futuregen Industrial Alliance, Inc., Morgan County, IL (United States)

    2016-04-01

    be helpful to plotting the course of, and successfully executing future large demonstration projects. This Final Scientific and Technical Report describes the technology and engineering basis of the project, inclusive of process systems, performance, effluents and emissions, and controls. Further, the project cost estimate, schedule, and permitting requirements are presented, along with a project risk and opportunity assessment. Lessons-learned related to these elements are summarized in this report. Companion reports Oxy-combustion further document the accomplishments and learnings of the project, including: A.01 Project Management Report which describes what was done to coordinate the various participants, and to track their performance with regard to schedule and budget B.02 Lessons Learned - Technology Integration, Value Improvements, and Program Management, which describes the innovations and conclusions that we arrived upon during the development of the project, and makes recommendations for improvement of future projects of a similar nature . B.03 Project Economics, which details the capital and operation costs and their basis, and also illustrates the cost of power produced by the plant with certain sensitivities. B.04 Power Plant, Pipeline, and Injection Site Interfaces, which details the interfaces between the two FutureGen projects B.05 Contractual Mechanisms for Design, Construction, and Operation, which describes the major EPC, and Operations Contracts required to execute the project.

  20. A LARGE LIFE INSURANCE COMPANY AUTOMATES. WORKFORCE IMPLICATIONS OF COMPUTER CONVERSION. AUTOMATION PROGRAM REPORT, NUMBER 3.

    Science.gov (United States)

    CIBARICH, AUGUST L.; AND OTHERS

    THIS WAS ONE OF 20 DEMONSTRATION PROJECTS INITIATED IN 11 STATES IN 1961-63 TO GAIN EXPERIENCE WITH LABOR MARKET PROBLEMS ARISING FROM CHANGING TECHNOLOGY AND MASS LAYOFFS. THE FUNDAMENTAL AIM WAS TO COMBINE ACTION AND RESEARCH TO DEMONSTRATE WHAT THE STATE EMPLOYMENT SERVICE COULD DO IN AREAS WHERE THE LABOR MARKET WAS RAPIDLY CHANGING.…

  1. Primary diffuse large B cell lymphoma developing at the ileocolonic anastomosis site after right hemicolectomy for adenocarcinoma: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Hye Yeon; Choi, Seung Joon; Kim, Hyung Sik; Kim, Jeong Ho; Choi, Hye Young [Dept. of Radiology, Gachon University Gil Hospital, Incheon (Korea, Republic of)

    2014-04-15

    Lymphoma is rarely associated with ileocolonic surgery. We report the imaging findings of primary diffuse large B-cell lymphoma arising in an ileocolonic anastomosis site, found five years after a right hemicolectomy for adenocarcinoma in the ascending colon.

  2. A case study for large-scale human microbiome analysis using JCVI's metagenomics reports (METAREP).

    Science.gov (United States)

    Goll, Johannes; Thiagarajan, Mathangi; Abubucker, Sahar; Huttenhower, Curtis; Yooseph, Shibu; Methé, Barbara A

    2012-01-01

    As metagenomic studies continue to increase in their number, sequence volume and complexity, the scalability of biological analysis frameworks has become a rate-limiting factor to meaningful data interpretation. To address this issue, we have developed JCVI Metagenomics Reports (METAREP) as an open source tool to query, browse, and compare extremely large volumes of metagenomic annotations. Here we present improvements to this software including the implementation of a dynamic weighting of taxonomic and functional annotation, support for distributed searches, advanced clustering routines, and integration of additional annotation input formats. The utility of these improvements to data interpretation are demonstrated through the application of multiple comparative analysis strategies to shotgun metagenomic data produced by the National Institutes of Health Roadmap for Biomedical Research Human Microbiome Project (HMP) (http://nihroadmap.nih.gov). Specifically, the scalability of the dynamic weighting feature is evaluated and established by its application to the analysis of over 400 million weighted gene annotations derived from 14 billion short reads as predicted by the HMP Unified Metabolic Analysis Network (HUMAnN) pipeline. Further, the capacity of METAREP to facilitate the identification and simultaneous comparison of taxonomic and functional annotations including biological pathway and individual enzyme abundances from hundreds of community samples is demonstrated by providing scenarios that describe how these data can be mined to answer biological questions related to the human microbiome. These strategies provide users with a reference of how to conduct similar large-scale metagenomic analyses using METAREP with their own sequence data, while in this study they reveal insights into the nature and extent of variation in taxonomic and functional profiles across body habitats and individuals. Over one thousand HMP WGS datasets and the latest open source code

  3. A case study for large-scale human microbiome analysis using JCVI's metagenomics reports (METAREP.

    Directory of Open Access Journals (Sweden)

    Johannes Goll

    Full Text Available As metagenomic studies continue to increase in their number, sequence volume and complexity, the scalability of biological analysis frameworks has become a rate-limiting factor to meaningful data interpretation. To address this issue, we have developed JCVI Metagenomics Reports (METAREP as an open source tool to query, browse, and compare extremely large volumes of metagenomic annotations. Here we present improvements to this software including the implementation of a dynamic weighting of taxonomic and functional annotation, support for distributed searches, advanced clustering routines, and integration of additional annotation input formats. The utility of these improvements to data interpretation are demonstrated through the application of multiple comparative analysis strategies to shotgun metagenomic data produced by the National Institutes of Health Roadmap for Biomedical Research Human Microbiome Project (HMP (http://nihroadmap.nih.gov. Specifically, the scalability of the dynamic weighting feature is evaluated and established by its application to the analysis of over 400 million weighted gene annotations derived from 14 billion short reads as predicted by the HMP Unified Metabolic Analysis Network (HUMAnN pipeline. Further, the capacity of METAREP to facilitate the identification and simultaneous comparison of taxonomic and functional annotations including biological pathway and individual enzyme abundances from hundreds of community samples is demonstrated by providing scenarios that describe how these data can be mined to answer biological questions related to the human microbiome. These strategies provide users with a reference of how to conduct similar large-scale metagenomic analyses using METAREP with their own sequence data, while in this study they reveal insights into the nature and extent of variation in taxonomic and functional profiles across body habitats and individuals. Over one thousand HMP WGS datasets and the latest

  4. Gaining Relational Competitive Advantages

    DEFF Research Database (Denmark)

    Hu, Yimei; Zhang, Si; Li, Jizhen

    2015-01-01

    Establishing strategic technological partnerships (STPs) with foreign partners is an increasingly studied topic within the innovation management literature. Partnering firms can jointly create sources of relational competitive advantage. Chinese firms often lack research and development (R......&D) capabilities but are increasingly becoming preferred technological partners for transnational corporations. We investigate an STP between a Scandinavian and a Chinese firm and try to explore how to gain relational competitive advantage by focusing on its two essential stages: relational rent generation...

  5. Learn and gain

    CERN Document Server

    Al-Alami, Suhair Eyad Jamal

    2013-01-01

    Initiating the slogan ""love it, live it"", Learn and Gain includes eight short stories, chosen to illustrate various modes of narration, as well as to provoke reflection and discussion on a range of issues. All texts utilized here illustrate how great writers can, with their insight and gift for words, help us to see the world we live in, in new probing and exciting ways. What characterises the book, the author believes, is the integration of the skills of literary competence, communicative c...

  6. Observation of super Coster-Kronig-pumped gain in Zn III.

    Science.gov (United States)

    Walker, D J; Barty, C P; Yin, G Y; Young, J F; Harris, S E

    1987-11-01

    We report the observation of laser gain in the vacuum ultraviolet pumped by super Coster-Kronig decay. Using a 5-J, 300-psec pump pulse of 1064-nm radiation, we have observed gain on transitions in Zn III at 127.0, 130.6, and 131.9 nm with total gains of exp(2.4), exp(5.1), and exp(3.2), respectively. The large branching ratios of the rapid super Coster-Kronig decay into a small number of final levels makes high-efficiency operation possible.

  7. Solar total energy: large scale experiment, Shenandoah, Georgia Site. Annual report, June 1978-June 1979

    Energy Technology Data Exchange (ETDEWEB)

    Ney, E.J.

    1979-07-01

    A background summary and a complete description of the progress and current status of activities relative to the Cooperative Agreement for the Solar Total Energy - Large Scale Experiment at the Bleyle Knitwear Plant at Shenandoah, Georgia are presented. A statement of objectives and an abstract of progress to date are included. This is followed by a short introduction containing a project overview, a summary of the participants and their respective roles, a brief description of the Solar Total Energy System (STES) design concept, and a chronological summary of progress to date. A general description of the site is given, a detailed report of progress is reported, and drawings and equipment lists are included. The closed-loop solar energy system planned for Shenandoah begins with circulation of Syltherm 800, a heat transfer fluid of the Dow-Corning Corporation, through the receiver tubes of a parabolic dish solar collector field. As solar energy is focused on the receivers, the heat transfer fluid is heated to approximately 399/sup 0/C (750/sup 0/F) and is pumped to a heat exchanger for immediate use, or to a thermal storage system for later use. Once in the heat exchanger, the fluid heats a working fluid that produces the steam required for operating the turbine. After performing this task, the heat transfer fluid returns to the collectors to repeat the cycle, while the steam turbine-generator system supplies the electrical demands for the knitwear plant and the STES. During STES operation, maximum thermal and electrical requirements of the application are expected to be at 1.08 MWth and 161 kWe, respectively. During the power generation phase, some of the steam is extracted for use as process steam in the knitwear manufacturing process, while exhaust steam from the turbine is passed through a condenser to produce hot water for heating, domestic use, and absorption air conditioning. (WHK)

  8. Tall towers for large wind turbines. Report from Vindforsk project V-342

    Energy Technology Data Exchange (ETDEWEB)

    Engstroem, Staffan; Lyrner, Tomas; Hassanzadeh, Manouchehr; Stalin, Thomas; Johansson, John

    2010-07-15

    The general rule of thumb has been to furnish a wind turbine with a tower as tall as the turbine diameter, with deviations downwards for high wind speed sites. In this report the statement is questioned, with special emphasis for wind turbines sited in forests. The aim of this project was to propose and calculate candidate types of tall towers for on-shore wind turbines in the 3 - 5 MW range, with special reference to siting in forests with a representative wind shear. During the project this scope has been more precisely defined to study 3 and 5 MW wind turbines with hub heights of 80 - 175 meters featuring the following tower solutions: 1. Steel shell tower designed in a conventional way with flanges and both longitudinal and transverse welds. 2. Steel shell tower with bolted friction joints only. 3. Concrete tower with pretensioned steel tendons. 4. Hybrid tower with a lower concrete part and an upper part built as a conventional steel shell. 5. Lattice tower. 6. Wooden tower. During the execution of the project the design of a total of 42 towers was outlined and calculated. Today the welded steel shell tower dominates the wind turbine market. Larger turbines and higher hub heights result in larger optimal tower base diameters. For the road transportation there are limitations due to bridges and other obstacles. In Sweden the limit for transports with special permits in general maximizes the diameter to 4,5 metres. To some extent it is still technically possible to build towers with a less than optimal diameter, but due to the high mass and the large wall thickness they tend to be uneconomical in comparison with other alternatives above a hub height of roughly 100 metres. In this report welded steel shell towers were outlined for 3 MW turbines up to a hub height of 150 metres whereas the limit for the 5 MW towers was 100 metres. When diameter restrictions tend to make welded towers uneconomical, the next logical choice is steel shell towers with bolted friction

  9. LARGE DENTIGEROUS CYST IN THE MAXILLARY SINUS LEADING TO DIPLOPIA AND NASAL OBSTRUCTION: CASE REPORT*

    Directory of Open Access Journals (Sweden)

    M. İsa KARA

    2015-04-01

    Full Text Available Dentigerous cysts are the most common developmental odontogenic cyst of the jaws. They are more frequent in males and although most often affected teeth are maxillary canines and mandibular third molars, they may also be related with supernumerary or an ectopically erupted tooth. Our aim was to report the management of ectopic third molar tooth related with a dentigerous cyst in maxillary sinus. 16 years old girl referred to our clinic with a complaint of painful swelling over her right cheek since past six months. All permanent teeth were present except the right upper third molar. External examination showed that the face was gently asymmetrical; levels of eye globes were abnormal. Radiographic examination revealed a cystic lesion related with ectopic third molar which located in the roof of the left maxillary sinus. Under local anesthesia, hard drain was inserted into the hole and the cystic pressure was decreased. After the six month of followup, the operation was performed under general anesthesia. The patient’s symptoms were resolved completely after surgery and remained symptom-free for over a postoperative follow-up period of 3 year. To avoid unwanted effects of a dentigerous cyst, unerupted tooth should be observed with radiographic imaging. Some untreated dentigerous cysts may grow large and have a potential to develop into an odontogenic tumor.

  10. Large scale gas injection test (Lasgit) performed at the Aespoe Hard Rock Laboratory. Summary report 2008

    Energy Technology Data Exchange (ETDEWEB)

    Cuss, R.J.; Harrington, J.F.; Noy, D.J. (British Geological Survey (United Kingdom))

    2010-02-15

    This report describes the set-up, operation and observations from the first 1,385 days (3.8 years) of the large scale gas injection test (Lasgit) experiment conducted at the Aespoe Hard Rock Laboratory. During this time the bentonite buffer has been artificially hydrated and has given new insight into the evolution of the buffer. After 2 years (849 days) of artificial hydration a canister filter was identified to perform a series of hydraulic and gas tests, a period that lasted 268 days. The results from the gas test showed that the full-scale bentonite buffer behaved in a similar way to previous laboratory experiments. This confirms the up-scaling of laboratory observations with the addition of considerable information on the stress responses throughout the deposition hole. During the gas testing stage, the buffer was continued to artificially hydrate. Hydraulic results, from controlled and uncontrolled events, show that the buffer continues to mature and has yet to reach full maturation. Lasgit has yielded high quality data relating to the hydration of the bentonite and the evolution in hydrogeological properties adjacent to the deposition hole. The initial hydraulic and gas injection tests confirm the correct working of all control and data acquisition systems. Lasgit has been in successful operation for in excess of 1,385 days

  11. Early Weight Gain Predicting Later Weight Gain Among Depot Medroxyprogesterone Acetate Users

    Science.gov (United States)

    LE, Yen-Chi L.; RAHMAN, Mahbubur; BERENSON, Abbey B.

    2009-01-01

    Objective To examine if early weight gain in depot medroxyprogesterone acetate (DMPA) users predicts continued excessive weight gain and to identify risk factors of early weight gain in DMPA users. Methods DMPA users (N=240) were assessed prior to initiating contraception and every 3 months for 36 months. Early weight gain was defined as over 5% baseline weight gain within 6 months of DMPA use. Mean weight gain at 6-month intervals was estimated based on early weight gain status (at or below 5% gain vs. above 5% gain). Multiple logistic and mixed-model regression analyses were used. Results About one-fourth of DMPA users had early weight gain. The mean weight gain of the at or below 5% group and above 5% group was 0.63 kg and 8.04 kg, 1.48 kg and 10.86 kg, and 2.49 kg and 11.08 kg after 12, 24, and 36 months (P < 0.001 at all observations), respectively. Early weight gainers also had a much steeper slope of weight gain over time than the regular weight gainers (0.35 kg/month vs. 0.08 kg/month, P < 0.001). Risk factors for early weight gain were: BMI less than 30 (OR 4.00, 95% confidence interval (CI): 1.513 – 10.455), parity (OR 2.23, 95% CI: 1.040 – 4.761), and self-reported increased appetite after 6 months of DMPA use (OR 3.06, 95% CI: 1.505 – 6.214). Conclusion Most DMPA users who gain excessive weight experience more than a 5% weight increase within 6 months. These data help physicians predict who is at risk of excessive gain and counsel them appropriately. PMID:19622988

  12. Learning and Teaching in Large Classes: A Bibliography. Project Report No.1.

    Science.gov (United States)

    Coleman, Hywel

    This bibliography has four major sections, including: (1) the learning and teaching of English in large classes; (2) the learning and teaching of other subjects in large classes; (3) class size and achievement; and (4) cultural background and large classes. Both published and unpublished materials are contained in the bibliography. The…

  13. Can improving teachers' knowledge of mathematics lead to gains in ...

    African Journals Online (AJOL)

    Can improving teachers' knowledge of mathematics lead to gains in ... We report on a quasi-experimental study examining the learning gains of ... Suggestions are made regarding the form and substance of such professional development.

  14. Anaplastic large cell lymphoma of the breast arising around mammary implant capsule: an Italian report.

    Science.gov (United States)

    Farace, Francesco; Bulla, Antonio; Marongiu, Francesco; Campus, Gian Vittorio; Tanda, Francesco; Lissia, Amelia; Cossu, Antonio; Fozza, Claudio; Rubino, Corrado

    2013-06-01

    Anaplastic large cell lymphoma (ALCL) of the breast is a very rare nonepithelial neoplasm. In the literature, this tumor has sometimes been described in proximity of breast implants (60 implant-related ALCL reported). In 2010, a patient who had undergone a right mastectomy and tissue expander/implant reconstruction for a "ductal" carcinoma 10 years before was referred to our unit for evaluation. On examination, an enlarged reconstructed right breast was found. The reconstructed breast did not show tenderness or signs of infection, ulceration, or breakdown. Mammograms and ultrasound scan did not suggest the presence of recurrent cancer, infection, deflation of the implant, or severe capsule contracture. The patient underwent mammary implant replacement. About 3 weeks after surgery, the patient came back to our unit for a new mild enlargement of the operated breast and the implant was removed. Three months later, the patient returned with a skin lesion in the right parasternal region. A radical excisional biopsy was performed under local anesthesia and the diagnosis of ALK-1-negative ALCL was finally made. The clinical and histological diagnosis of this disease is difficult as it can often be mistaken for a simple seroma (breast enlargement), an infection, or an unspecific reaction to silicone (redness and/or tension of the skin, itching, and fever). We strongly suggest considering ALCL in any patient with a spontaneous breast seroma lasting more than 6 months after mammary prosthesis implantation. The suspicion of ALCL must be suggested to the pathologist immediately. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

  15. The saddle connective tissue graft: a periodontal plastic surgery technique to obtain soft tissue coronal gain on immediate implants. A case report.

    Science.gov (United States)

    González, David; Cabello, Gustavo; Olmos, Gema; Niñoles, Carlos L

    2015-01-01

    Based on recent studies regarding the advantages of flapless immediate implants on the maintenance of the soft tissue architecture (especially at papillae level) in those situations where it is necessary to extract an anterior tooth, this case report describes a clinical procedure designed to replace a hopeless central incisor (2.1) showing root resorption adjacent to an implant-supported crown (1.1), whose gingival margin is 2 mm coronal regarding the hopeless tooth to be replaced. After the extraction of the hopeless tooth (2.1), a flapless immediate implant was placed. The implant-bone gap was then filled with bone substitute and a palatal connective tissue graft was placed ad modum saddle extending at buccal level from apical to the mucogingival line, sealing the socket and extending until 6 mm at palatal level ad modum saddle. This procedure allowed symmetry of the soft tissue margins between the two implants (1.1 and 2.1) to be obtained as well as the preservation of the inter-implant papillae (1.1).

  16. Change, Gain and Loss

    Institute of Scientific and Technical Information of China (English)

    Fu Mengzi

    2006-01-01

    @@ Five years have passed since the September 11 terrorist attacks occurred. America's counter-terrorism campaign is still on the way.Besides the momentary monumental significance of the fifth anniversary, five years is still too short in regard to the long-term counter-terrorism campaign. Yet, America's president's tenure is eight years at best; most of Bush's presidency time has passed. Five years ago, the U. S. encountered the most serious terrorist attack; the whole nation formed a consensus that counter-terrorism is its utmost priority. President Bush once enjoyed a support rate as high as 90% for over 16 months. But five years later, the trend changes. People can not help but ask: what are the gains and losses of the Republican Party in dealing with national security affairs?

  17. The Effect of Board Independence on the Sustainability Reporting Practices of Large U.S. Firms \\

    Directory of Open Access Journals (Sweden)

    David N. Herda

    2012-12-01

    firms with a greater proportion of independent board members are: 1 more likely to publish standalone sustainability reports, and 2 more likely to publish higher quality sustainability reports. This paper contributes to prior literature that reports somewhat mixed results on the effect of board independence on voluntary disclosure.

  18. 78 FR 54996 - Information Reporting by Applicable Large Employers on Health Insurance Coverage Offered Under...

    Science.gov (United States)

    2013-09-09

    ...) minimizing cost and administrative tasks for the reporting entities and individuals, and (3) providing the... section 6056 reporting is the common law employer. Disregarded entities are treated for section 4980H... purposes, so that the reporting requirements under section 6056 are imposed on a disregarded entity that...

  19. Large infrapatellar ganglionic cyst of the knee fat pad: a case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Ilias Apostolos

    2011-08-01

    Full Text Available Abstract Introduction Large ganglionic cystic formations arising from the infrapatellar fat pad are quite uncommon and only a few are mentioned in the literature. An open excision in these cases is mandatory. Case presentation We report the case of a large infrapatellar fat pad ganglion in a 37-year-old Greek man with chronic knee discomfort. The ganglionic cyst originated from the infrapatellar fat pad and had no intrasynovial extension. The final diagnosis was determined with magnetic resonance imaging of the knee, and the lesion was treated with surgery. Conclusions These lesions are asymptomatic in most cases but often are misdiagnosed as meniscal or ligamentous lesions of the knee joint. Nowadays, the therapeutic trend for such lesions is arthroscopic excision, but when there is a large ganglion, as in this case report, the treatment should be an open and thorough resection. This report is intended mostly but not exclusively for clinical physicians and radiologists.

  20. Evaluation of a Web-based Error Reporting Surveillance System in a Large Iranian Hospital.

    Science.gov (United States)

    Askarian, Mehrdad; Ghoreishi, Mahboobeh; Akbari Haghighinejad, Hourvash; Palenik, Charles John; Ghodsi, Maryam

    2017-08-01

    Proper reporting of medical errors helps healthcare providers learn from adverse incidents and improve patient safety. A well-designed and functioning confidential reporting system is an essential component to this process. There are many error reporting methods; however, web-based systems are often preferred because they can provide; comprehensive and more easily analyzed information. This study addresses the use of a web-based error reporting system. This interventional study involved the application of an in-house designed "voluntary web-based medical error reporting system." The system has been used since July 2014 in Nemazee Hospital, Shiraz University of Medical Sciences. The rate and severity of errors reported during the year prior and a year after system launch were compared. The slope of the error report trend line was steep during the first 12 months (B = 105.727, P = 0.00). However, it slowed following launch of the web-based reporting system and was no longer statistically significant (B = 15.27, P = 0.81) by the end of the second year. Most recorded errors were no-harm laboratory types and were due to inattention. Usually, they were reported by nurses and other permanent employees. Most reported errors occurred during morning shifts. Using a standardized web-based error reporting system can be beneficial. This study reports on the performance of an in-house designed reporting system, which appeared to properly detect and analyze medical errors. The system also generated follow-up reports in a timely and accurate manner. Detection of near-miss errors could play a significant role in identifying areas of system defects.

  1. Gain Efficient L-band EDFA With Dynamic Gain Equalization

    Institute of Scientific and Technical Information of China (English)

    Xiaoli Hui; Rujian Lin

    2003-01-01

    A gain efficient L-band erbium-doped fiber amplifier with dynamic gain equalization is presented. Using a single fiber Bragg grating and a static equalizer, the gain is clamped at 27dB with less than 0.5dB variations over 35nm.

  2. Paul Scherrer Institute Scientific Report 1998. Volume VI: Large Research Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, Guenter; Bercher, Renate; Buechli, Carmen; Foroughi, Fereydoun; Meyer, Rosa [eds.

    1999-09-01

    The department GFA (Grossforschungsanlagen, Large Research Facilities) has been established in October 1998 and its main duty is operation, maintenance and development of the PSI accelerators, the spallation neutron source and the beam transport systems for pions and muons. A large effort of this group concerns the planning and co-ordination of the assembly of the Swiss Light Source (SLS). (author) figs., tabs., refs.

  3. Large cell neuroendocrine carcinoma of the parotid gland: case report and literature review.

    Science.gov (United States)

    Casas, Pablo; Bernáldez, Ricardo; Patrón, Mercedes; López-Ferrer, Pilar; García-Cabezas, Miguel A

    2005-03-01

    A 74-year-old male presented with a large polinodular mass in the neck. Fine needle aspiration cytology (FNAC) showed an undifferentiated large cell carcinoma. Computed tomography (CT) showed a large parotid mass with multiple satelite nodules. The remaining radiological studies were normal. Radical parotidectomy was performed. The tumor was a large cell carcinoma with neuroendocrine features and positive immunostain for neuroendocrine markers. The patient received postoperative radiotherapy and was free of tumor eight months later. Only four cases of large cell neuroendocrine carcinoma (LCNEC) of the salivary gland have been communicated. All of them have involved the parotid gland. This tumor presents in elderly patients as a large infiltrating parotid mass. Fine needle aspiration cytology serves to recognize the carcinoma, but it fails in recognizing the neuroendocrine features of the tumor. The histopathological features of this tumor are the same as in other organs. Chromogranin and synaptophysin are useful immunohistochemical markers. A primary location of the tumor in another organ, specially the lung, should be ruled out. Surgery is the main treatment modality and can be complemented with postoperative radiotherapy. The prognosis seems to be poor. More studies are needed to better define the therapeutical alternatives and prognostic factors of these rare tumors.

  4. Reconstruction of large tibial bone defects following osteosarcoma resection using bone transport distraction: A report of two cases

    Science.gov (United States)

    Yang, Zhengming; Jin, Libin; Tao, Huimin; Yang, Disheng

    2016-01-01

    The clinical efficiency of bone transport distraction osteogenesis in the reconstruction of large tibial defects following resection of osteosarcoma remains unclear. The current study presents two cases of large tibial defects treated with bone transport distraction using an Orthofix external fixator. Case 1 was a 29-year-old man with a tibial defect 11 cm in length, while case 2 was a 16-year-old girl with a 15-cm-long defect. Bone transport distraction osteogenesis was initiated for the both cases on day 14 following resection of the tibial osteosarcoma. Bone transport distraction in case 1 and 2 was continued for 16 and 28 months, respectively, and the patients were followed up for 51 and 56 months, respectively. The two patients did not exhibit any signs of tumor recurrence or tumor metastasis during the follow-up period. The Musculoskeletal Tumor Society functional scores at final follow-up visits were 22 and 18 for case 1 and 2, respectively. Based on the experience gained in these 2 cases, a bone transport is a viable option for the reconstruction of large tibial defects following osteosarcoma resection. PMID:27446450

  5. Weight Gain during Pregnancy

    Science.gov (United States)

    ... Global Map Premature birth report card Careers Archives Pregnancy Before or between pregnancies Nutrition, weight & fitness Prenatal ... virus and pregnancy Folic acid Medicine safety and pregnancy Birth defects prevention Learn how to help reduce ...

  6. Beliefs about weight gain among young adults: potential challenges to prevention.

    Science.gov (United States)

    Gokee LaRose, Jessica; Gorin, Amy A; Clarke, Megan M; Wing, Rena R

    2011-09-01

    This study assessed young adults' beliefs about weight gain with the goal of improving intervention efforts with this high-risk group. A total of 1,347 incoming freshman (45% male; 81% non-Hispanic white; 18.6 ± 1.7 years; BMI = 23.3 ± 2.3 kg/m2) at a large state university in the Northeast completed a survey designed to assess: (i) degree of concern about weight gain, (ii) level of interest in weight control programs, and (iii) the most acceptable setting for an intervention. Perceptions about freshman weight gain were consistent across gender, with men and women reporting that the average student gains 5.4 ± 1.9 kg and 5.6 ± 1.9 kg respectively. Men in general were less concerned about weight gain (P gain 6.2 ± 4.2 kg before becoming concerned compared to 3.1 ± 1.7 kg among women (P gaining weight than normal weight (NW) men (P gain less weight before becoming concerned (5.0 ± 3.0 kg vs. 6.7 ± 4.5 kg, P prevent weight gain (17% men vs. 40% women, P prevention program did not vary by weight status (P = 0.59). Both men and women were most likely to report a willingness to attend classes on a local college campus compared to other settings. Findings highlight the challenges of engaging young adults in weight gain prevention programs, particularly young men, and are discussed in terms of implications for improving recruitment efforts and intervention development with this population.

  7. Leaving home for college and gaining independence

    NARCIS (Netherlands)

    Mulder, C.H.; Clark, W.A.V.

    2002-01-01

    As more and more young US adults attend college it has become an increasingly important filter in the process of becoming an independent household. Now for a large number of young adults living in the USA, living away at college is a first step in the process of gaining residential and economic

  8. How Subsidiaries Gain Power in Multinational Corporations

    DEFF Research Database (Denmark)

    Mudambi, Ram; Pedersen, Torben; Andersson, Ulf

    2014-01-01

    This study focuses on how power is gained within large organizations, such as the intra-organizational network of MNCs. Drawing on resource dependence literature, this study develops and empirically tests a set of hypotheses aimed at explaining the multifaceted nature of power and decision making...

  9. Large gastrointestinal stromal tumor and advanced adenocarcinoma in the rectum coexistent with an incidental prostate carcinoma: A case report

    Directory of Open Access Journals (Sweden)

    Toshiaki Suzuki

    2014-01-01

    CONCLUSION: Radical surgery with perioperative adjuvant chemotherapy using tyrosine kinase inhibitors is the choice for treatment of large GISTs with a malignant potential. Our report suggests that aggressive surgical approach would be feasible, when a secondary tumor is present near the GIST.

  10. Cost optimizing of large-scale offshore wind farms. Summary and conclusion. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    The project comprises investigation of the technical and economical possibilities of large-scale offshore wind farms at 3 locations in the eastern Danish waters: Roedsand and Gedser Rev located south of the islands of Falster and Lolland and Omoe Staagrunde located south-west of the island of Zealand plus experiences obtained from British and German offshore wind energy projects. The project included wind and wave measurements at the above 3 locations, data collection, data processing, meteorological analysis, modelling of wind turbine structure, studies of grid connection, design and optimisation of foundations plus estimates of investments and operation and maintenance costs. All costs are in ECU on 1997 basis. The main conclusion of the project financed by the European Commission is: Areas are available for large scale offshore wind farms in the Danish waters; A large wind potential is found on the sites; Park layouts of projects consisting of around 100 wind turbines each has been developed; Design of the foundations has been optimised radically compared to previous designs; A large potential for optimising of the wind turbine design and operation has been found; Grid connection of the first proposed large wind farms is possible with only minor reinforcement of the transmission system; The visual impact is not prohibitive for the projects; A production cost of 4-5 ECUcent/kWh is competitive with current onshore projects. All in all, the results from this project have proven to be very useful for the further development of large-scale wind farms in the Danish waters, and thereby an inspiration for similar projects in other (European) countries. (LN)

  11. Report on the impacts of large research infrastructures on economic innovation and on society Case studies at CERN

    CERN Document Server

    OECD, Paris

    2014-01-01

    This report is an examination of some of the economic and societal impacts of a well-known international high-energy physics infrastructure: the European Organisation for Nuclear Research, CERN, with special emphasis on its latest and most prominent scientific installation, the Large Hadron Collider (LHC). While both CERN and the LHC are, to a large extent, unique among research infrastructures, it is hoped that the case studies, analyses and conclusions in this report will make a useful contribution to the wider debate concerning the impacts of investments in large basic research facilities. Specifically, an enumeration and analysis of the pertinent issues and options should be a useful resource for persons who are contemplating the establishment of any major new international collaboration.

  12. Paul Scherrer Institut annual report 1996. Annex IIIA: solid state research at large facilities

    Energy Technology Data Exchange (ETDEWEB)

    Baltensperger, U.; Lorenzen, R. [eds.] [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1997-09-01

    A progress report is given on research performed during 1996 in the fields of the spallation neutron source, ion beam physics, radio- and environmental chemistry, neutron scattering and astrophysics. figs., tabs., refs.

  13. Bringing About Brain Gain

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    China attempts to lure talent from overseas The first batch of young researchers selected for China’s 1,000 Young Talents Program was announced on November 11. The program, which started in early 2011,will select 2,000 topnotch young researchers with overseas expe-rience over the next five years. Successful applicants will receive large grants and other benefits from the Chinese Government.

  14. Workshop Report on Additive Manufacturing for Large-Scale Metal Components - Development and Deployment of Metal Big-Area-Additive-Manufacturing (Large-Scale Metals AM) System

    Energy Technology Data Exchange (ETDEWEB)

    Babu, Sudarsanam Suresh [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Manufacturing Demonstration Facility; Love, Lonnie J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Manufacturing Demonstration Facility; Peter, William H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Manufacturing Demonstration Facility; Dehoff, Ryan [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Manufacturing Demonstration Facility

    2016-05-01

    Additive manufacturing (AM) is considered an emerging technology that is expected to transform the way industry can make low-volume, high value complex structures. This disruptive technology promises to replace legacy manufacturing methods for the fabrication of existing components in addition to bringing new innovation for new components with increased functional and mechanical properties. This report outlines the outcome of a workshop on large-scale metal additive manufacturing held at Oak Ridge National Laboratory (ORNL) on March 11, 2016. The charter for the workshop was outlined by the Department of Energy (DOE) Advanced Manufacturing Office program manager. The status and impact of the Big Area Additive Manufacturing (BAAM) for polymer matrix composites was presented as the background motivation for the workshop. Following, the extension of underlying technology to low-cost metals was proposed with the following goals: (i) High deposition rates (approaching 100 lbs/h); (ii) Low cost (<$10/lbs) for steel, iron, aluminum, nickel, as well as, higher cost titanium, (iii) large components (major axis greater than 6 ft) and (iv) compliance of property requirements. The above concept was discussed in depth by representatives from different industrial sectors including welding, metal fabrication machinery, energy, construction, aerospace and heavy manufacturing. In addition, DOE’s newly launched High Performance Computing for Manufacturing (HPC4MFG) program was reviewed. This program will apply thermo-mechanical models to elucidate deeper understanding of the interactions between design, process, and materials during additive manufacturing. Following these presentations, all the attendees took part in a brainstorming session where everyone identified the top 10 challenges in large-scale metal AM from their own perspective. The feedback was analyzed and grouped in different categories including, (i) CAD to PART software, (ii) selection of energy source, (iii

  15. Large neonatal thoracoabdominal aneurysm : case report and review of the literature

    NARCIS (Netherlands)

    Buddingh, K. Tim; Zeebregts, Clark J.; Tilanus, Martijn E. C.; Roofthooft, Marc T. R.; Broens, Paul M. A.

    We present a neonate with a large saccular aneurysm of the thoracoabdominal aorta, extending from the intrathoracic aorta to the left common iliac artery. No underlying cause could be identified. Despite an early diagnosis, the aneurysm was deemed inoperable because of the lengthy involvement and

  16. An Investigation of Energy Consumption and Cost in Large Air-Conditioned Buildings. An Interim Report.

    Science.gov (United States)

    Milbank, N. O.

    Two similarly large buildings and air conditioning systems are comparatively analyzed as to energy consumption, costs, and inefficiency during certain measured periods of time. Building design and velocity systems are compared to heating, cooling, lighting and distribution capabilities. Energy requirements for pumps, fans and lighting are found to…

  17. Renal failure with a large bladder calculus related to a foreign body: a case report

    Science.gov (United States)

    Minter, Janelle; Chiovaro, Joseph

    2014-01-01

    Key Clinical Message We encountered a patient with renal failure in the setting of long-standing difficulty urinating, which he previously treated with intermittent self-catheterizations. Imaging showed a large urinary calculus in the bladder. This case illustrates the importance of taking a detailed history and the dramatic long-term effects of bladder calculi. PMID:25356243

  18. [Impaired lung function and anemia from large hiatal hernia: a case report].

    Science.gov (United States)

    Suppa, Marianna; Colzi, Marina; Magnanelli, Elisa; Migliozzi, Elisa; Negri, Silvia; Millarelli, Federica; Coppola, Alessandro

    2013-05-01

    We present the clinical case of a 54 years old man who accessed for dyspnea and severe anemia. After being transfused, he underwent to gastroscopy, which showed an erosive gastritis with large hiatal hernia. The hernia was surgically reduced with laparoscopic hiatoplastic and Nissen-Rossetti fundoplication. In conclusion, dyspnea is not merely a medical competence but also a surgical one.

  19. Primary Intravascular large B-cell lymphoma of lung: a report of one case and review

    Directory of Open Access Journals (Sweden)

    Yu Hui

    2012-06-01

    Full Text Available Abstract Objective To investigate the clinicopathological features of primary intravascular large B-cell lymphoma of lung. Methods A case of primary pulmonary intravascular large B-cell lymphoma was analysed in histopathology and immunophenotype. Results The patient is a 42-year-old female who had cough for one year. Computed tomography showed ground-glass opacities and small nodules in bilateral lung fields. Histopathology demonstrated accumulation of similar sized neoplastic cells within alveolar capillaries, widening the alveolar septae. The alveolar structure sustained in part of districtions. Immunohistologically, the tumor cells were positive for CD20 and negative for CD3,CK, which were similar to the diffuse large B-cell lymphoma. Conclusions Intravascular large B-cell lymphoma is an uncommon type of non-Hodgkin’s lymphoma. Primary pulmonary presentation is even more rare. The diagnosis is based on the histopathology and immunohistochemistry. Virtual slides The virtual slide(s for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2076991810705433.

  20. Using Technology To Implement Active Learning in Large Classes. Technical Report.

    Science.gov (United States)

    Gerace, William J.; Dufresne, Robert J.; Leonard, William J.

    An emerging technology, classroom communication systems (CCSs), has the potential to transform the way we teach science in large-lecture settings. CCSs can serve as catalysts for creating a more interactive, student-centered classroom in the lecture hall, thereby allowing students to become more actively involved in constructing and using…

  1. 75 FR 27464 - Special Reporting, Analysis and Contingent Resolution Plans at Certain Large Insured Depository...

    Science.gov (United States)

    2010-05-17

    ... complex financial parent companies to submit to the FDIC analysis, information, and contingent resolution... IDIs with greater than $10 billion in total assets that are owned or controlled by parent companies... that exist within even larger conglomerate and multinational structures. These large and complex IDIs...

  2. Final Report: Large-Scale Optimization for Bayesian Inference in Complex Systems

    Energy Technology Data Exchange (ETDEWEB)

    Ghattas, Omar [The University of Texas at Austin

    2013-10-15

    The SAGUARO (Scalable Algorithms for Groundwater Uncertainty Analysis and Robust Optimiza- tion) Project focuses on the development of scalable numerical algorithms for large-scale Bayesian inversion in complex systems that capitalize on advances in large-scale simulation-based optimiza- tion and inversion methods. Our research is directed in three complementary areas: efficient approximations of the Hessian operator, reductions in complexity of forward simulations via stochastic spectral approximations and model reduction, and employing large-scale optimization concepts to accelerate sampling. Our efforts are integrated in the context of a challenging testbed problem that considers subsurface reacting flow and transport. The MIT component of the SAGUARO Project addresses the intractability of conventional sampling methods for large-scale statistical inverse problems by devising reduced-order models that are faithful to the full-order model over a wide range of parameter values; sampling then employs the reduced model rather than the full model, resulting in very large computational savings. Results indicate little effect on the computed posterior distribution. On the other hand, in the Texas-Georgia Tech component of the project, we retain the full-order model, but exploit inverse problem structure (adjoint-based gradients and partial Hessian information of the parameter-to- observation map) to implicitly extract lower dimensional information on the posterior distribution; this greatly speeds up sampling methods, so that fewer sampling points are needed. We can think of these two approaches as "reduce then sample" and "sample then reduce." In fact, these two approaches are complementary, and can be used in conjunction with each other. Moreover, they both exploit deterministic inverse problem structure, in the form of adjoint-based gradient and Hessian information of the underlying parameter-to-observation map, to achieve their speedups.

  3. Improved design for large wind turbine blades of fibre composites (Phase 4) - Summary report

    DEFF Research Database (Denmark)

    Sørensen, Bent F.; Toftegaard, Helmuth Langmaack; Goutianos, Stergios

    growth with large scale bridging and the use of cohesive laws in finite element programmes for simulating wind turbine blade failure. An overview is given of the methods and the major research results of the project. The implementation of the knowledge in the industry is discussed. Finally, some ideas......Results are summarised for the project "Improved design for large wind turbine blades (Phase 4)", partially supported by the Danish Energy Agency under the Ministry of Climate and Energy through the EUDP journal no.: 33033-0267. The aim of the project was to develop new and better design methods...... for wind turbine blades, so that uncertainties associated with damage and defects can be reduced. The topics that are studied include buckling-driven delamination of flat load-carrying laminates, cracking along interfaces in material joints (fracture mechanical characterisation and modelling), cyclic crack...

  4. A large uterine leiomyoma leading to non-puerperal uterine inversion: A case report

    Directory of Open Access Journals (Sweden)

    Batool Teimoori

    2017-08-01

    Full Text Available Background: Although leiomyomas are the most common gynecologic disorders, non-puerperal uterine inversion due to leiomyoma is considered as a rare clinical problem. This condition can occur as a complication of a large sub-mucous leiomyoma that leads to dilate cervix and protrude into vagina. The patient may have several symptoms such as heavy vaginal bleeding, pelvic pain and intermittent acute urinary retention. Case: We presented a 32-year-old nulliparous woman with 17 years of unexplained infertility and diagnosis of a large vaginal prolapsed non-pedunculated leiomyoma. Conclusion: Haultain’s procedure was used to reposition uterine inversion and remove leiomyoma through a posterior incision, using laparotomy

  5. Improved design for large wind turbine blades of fibre composites (Phase 4) - Summary report

    Energy Technology Data Exchange (ETDEWEB)

    Soerensen, B.F.; Toftegaard, H.; Goutanos, S. (Risoe DTU, Materials Research Div., Roskilde (Denmark)); Branner, K.; Berring, P. (Risoe DTU, Wind Energy Div., Roskilde (Denmark)); Lund, E. (Aalborg Univ., Dept. of Mechanical Engineering, Aalborg (Denmark)); Wedel-Heinen, J. (Vestas Wind System, Randers (Denmark)); Garm, J.H. (LM Wind Power, Kolding (Denmark))

    2010-06-15

    Results are summarised for the project 'Improved design for large wind turbine blades (Phase 4)', partially supported by the Danish Energy Agency under the Ministry of Climate and Energy through the EUDP journal no.: 33033-0267. The aim of the project was to develop new and better design methods for wind turbine blades, so that uncertainties associated with damage and defects can be reduced. The topics that are studied include buckling-driven delamination of flat load-carrying laminates, cracking along interfaces in material joints (fracture mechanical characterisation and modelling), cyclic crack growth with large scale bridging and the use of cohesive laws in finite element programmes for simulating wind turbine blade failure. An overview is given of the methods and the major research results of the project. The implementation of the knowledge in the industry is discussed. Finally, some ideas for future research activities are considered. (author)

  6. A large extraskeletal chondroma in the hand of an elderly patient--a case report.

    Science.gov (United States)

    Ikeda, Kazuo; Osamura, Naoki; Kasashima, Satomi

    2013-01-01

    This paper examines a case of extraskeletal chondroma in the hand of an 82-year-old female, first noticed about two years ago. Magnetic resonance imaging showed a mass in the carpal tunnel which extended from the wrist to the palm. The tumor was located between the thenar area and the hypothenar area at the palm level. There was no continuity to the carpal bone or radius bone. The entire size of the tumor was 120 mm × 45 mm × 42 mm. Although extraskeletal chondroma is sometimes seen, a large one in the hand is extremely rare. Since the tumor was too large to excise totally because median nerve entrapped it, it was divided into two parts and excised. After the operation, there was no neurological deficit or pain in the median nerve lesion.

  7. RECURRENT HEPATIC ENCEPHALOPATHY IN A CIRRHOTIC PATIENT WITH LARGE GASTRORENAL SHUNT: ONE CASE REPORT

    Institute of Scientific and Technical Information of China (English)

    汪余勤; 汪保灿; 顾胜利; 范建高

    2011-01-01

    We presented a case of chronic recurrent hepatic encephalopathy occurring in a liver cirrhosis patient (Child Pugh A) with a large gastrorenal shunt and a review of the literature focusing on diagnosis and management. Computed tomography (CT) demonstrated an atrophic liver, splenomegaly, varices at the gastric fundic and the splenic hilum, and a highly tortuous shunt vessel between the gastric fundic varices and the left renal vein. Ultrasonography revealed the portal vein diameter was 0.8 cm; and portal ve...

  8. Cost optimizing of large-scale offshore wind farms. Appendix A to D. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    Volume 2 contains reports prepared by Nellemann, Nielsen and Rauschenberger A/S (NNR) and NNR`s 2 sub-consultants Danish Geotechnical Institute (DGI) and Danish Hydraulic Institute (DHI). It contains Appendix A - Geotechnical Review and Summary prepared by Nellemann, Nielsen and Rauschenberger A/S; Appendix B - Geotechnical Investigations, factual reports for geotechnical investigations and laboratory tests prepared by Danish Geotechnical Institute; Appendix C - Hydraulic Assessment prepared by Danish Hydraulic Institute; Appendix D - Conceptual Design and Optimisation prepared by Nellemann, Nielsen and Rauschenberger A/S. (LN)

  9. Physics gains attraction?

    Science.gov (United States)

    2000-01-01

    A recent report from the American Institute of Physics has indicated that high school enrolments in physics in the USA have reached their highest level since World War II. Figures for the last decade show an increase in the proportion of high school students taking physics from 20 to 28% (800Â 000 students now), according to Physics Today (October 1999, p 68). The report, Maintaining Momentum: High School Physics for a New Millennium , was based on a 1997 survey of high school physics teachers, the fourth such since the mid-1980s. One conclusion drawn by the report's authors was that a broader range of physics courses is now offered, with increased popularity of `conceptual' physics courses using little algebra or trigonometry over the last ten years. The proportion of students with the strongest maths abilities now taking advanced placement or second-year physics has doubled since 1987. In addition the physics appeal has been noted among high school girls, where the percentage taking physics has risen from 39 to 47% in the ten years to 1997. These female students do not, however, seem to extend their studies into advanced placements or even into teaching physics (women constitute just a quarter of high school teachers of the subject). Sadly the good news is outweighed by the fact that physics still registers the lowest enrolments of all the high school sciences - about half those in chemistry for example. Indeed only around 1% of high school students have taken two years of physics before they graduate, which represents a much lower proportion than in many European and Asian countries. The full report can be viewed at the AIP's statistics division's homepage: www.aip.org/statistics/trends/hstrends.htm whilst summaries of the document are available free from the AIP, Education and Employment Statistics Division, One Physics Ellipse, College Park, MD 20740, USA.

  10. Systematic Analysis of Self-Reported Comorbidities in Large Cohort Studies – A Novel Stepwise Approach by Evaluation of Medication

    Science.gov (United States)

    Wacker, Margarethe; Holle, Rolf; Biertz, Frank; Nowak, Dennis; Huber, Rudolf M.; Söhler, Sandra; Vogelmeier, Claus; Ficker, Joachim H.; Mückter, Harald; Jörres, Rudolf A.

    2016-01-01

    Objective In large cohort studies comorbidities are usually self-reported by the patients. This way to collect health information only represents conditions known, memorized and openly reported by the patients. Several studies addressed the relationship between self-reported comorbidities and medical records or pharmacy data, but none of them provided a structured, documented method of evaluation. We thus developed a detailed procedure to compare self-reported comorbidities with information on comorbidities derived from medication inspection. This was applied to the data of the German COPD cohort COSYCONET. Methods Approach I was based solely on ICD10-Codes for the diseases and the indications of medications. To overcome the limitations due to potential non-specificity of medications, Approach II was developed using more detailed information, such as ATC-Codes specific for one disease. The relationship between reported comorbidities and medication was expressed by a four-level concordance score. Results Approaches I and II demonstrated that the patterns of concordance scores markedly differed between comorbidities in the COSYCONET data. On average, Approach I resulted in more than 50% concordance of all reported diseases to at least one medication. The more specific Approach II showed larger differences in the matching with medications, due to large differences in the disease-specificity of drugs. The highest concordance was achieved for diabetes and three combined cardiovascular disorders, while it was substantial for dyslipidemia and hyperuricemia, and low for asthma. Conclusion Both approaches represent feasible strategies to confirm self-reported diagnoses via medication. Approach I covers a broad spectrum of diseases and medications but is limited regarding disease-specificity. Approach II uses the information from medications specific for a single disease and therefore can reach higher concordance scores. The strategies described in a detailed and

  11. Gain Flattening Filter Canceling Temperature Dependence of EDFA s gain

    Institute of Scientific and Technical Information of China (English)

    M.; Ohmura; Y.; Ishizawa; H.; Nakaji; K.; Hashimoto; T.; Shibata; M.; Shigehara; A.; Inoue

    2003-01-01

    We have developed a gain flattening filter (GFF) for an erbium doped fiber (EDF) without temperature control systems. This GFF, which consists of temperature-sensitive long period gratings (LPGs) and a temperature compensated slanted fiber Bragg grating (SFBG), follows the gain shift of EDF with temperature. Gain variation of the EDFA less than 0.25dBp-p was achieved with the bandwidth of 37nm, and the temperature range 0-65℃ without any temperature control systems.

  12. Short- and long-term earthquake triggering along the strike-slip Kunlun fault, China: Insights gained from the Ms 8.1 Kunlun earthquake and other modern large earthquakes

    Science.gov (United States)

    Xie, Chaodi; Lei, Xinglin; Wu, Xiaoping; Hu, Xionglin

    2014-03-01

    Following the 2001 Ms8.1 Kunlun earthquake, earthquake records of more than 10 years, in addition to more than one century's records of large earthquakes, provide us with a chance to examine short-term (days to a few years) and long-term (years to decades) seismic triggering following a magnitude ~ 8 continental earthquake along a very long strike-slip fault, the Kunlun fault system, located in northern Tibet, China. Based on the calculations of coseismic Coulomb stress changes (ΔCFS) from the larger earthquake and post-seismic stress changes due to viscoelastic stress relaxation in the lower crust and upper mantle, we examined the temporal evolution of seismic triggering. The ETAS (epidemic type aftershocks sequence) model shows that the seismic rate in the aftershock area over ~ 10 years was higher than the background seismicity before the mainshock. Moreover, we discuss long-term (years to decades) triggering and the evolution of stress changes for the sequence of five large earthquakes of M ≥ 7.0 that ruptured the Kunlun fault system since 1937. All subsequent events of M ≥ 7.0 occurred in the regions of positive accumulated ΔCFS. These results show that short-term (up to 200 days in our case) triggering along the strike-slip Kunlun fault is governed by coseismic stress changes, while long-term triggering is somewhat due to post-seismic Coulomb stress changes resulting from viscoelastic relaxation.

  13. The Biology of Intron Gain and Loss

    DEFF Research Database (Denmark)

    Jeffares, Daniel C; Mourier, Tobias; Penny, David

    2006-01-01

    Intron density in eukaryote genomes varies by more than three orders of magnitude, so there must have been extensive intron gain and/or intron loss during evolution. A favored and partial explanation for this range of intron densities has been that introns have accumulated stochastically in large...... eukaryote genomes during their evolution from an intron-poor ancestor. However, recent studies have shown that some eukaryotes lost many introns, whereas others accumulated and/or gained many introns. In this article, we discuss the growing evidence that these differences are subject to selection acting...... on introns depending on the biology of the organism and the gene involved....

  14. FEL gain optimisation and spontaneous radiation

    Energy Technology Data Exchange (ETDEWEB)

    Bali, L.M.; Srivastava, A.; Pandya, T.P. [Lucknow Univ. (India)] [and others

    1995-12-31

    Colson have evaluated FEL gains for small deviations from perfect electron beam injection, with radiation of the same polarisation as that of the wiggler fields. We find that for optimum gain the polarisation of the optical field should be the same as that of the spontaneous emission under these conditions. With a helical wiggler the axial oscillations resulting from small departures from perfect electron beam injection lead to injection dependent unequal amplitudes and phases of the spontaneous radiation in the two transverse directions. Viewed along the axis therefore the spontaneous emission is elliptically polarised. The azimuth of the ellipse varies with the difference of phase of the two transverse components of spontaneous emission but the eccentricity remains the same. With planar wigglers the spontaneous emission viewed in the axial direction is linearly polarised, again with an injection dependent azimuth. For optimum coherent gain of a radiation field its polarisation characteristics must be the same as those of the spontaneous radiation with both types of wiggler. Thus, with a helical wiggler and the data reported earlier, an increase of 10% in the FEL gain at the fundamental frequency and of 11% at the fifth harmonic has been calculated in the small gain per pass limit. Larger enhancements in gain may result from more favourable values of input parameters.

  15. The shadow effect of large wind farms: measurements, data analysis and modelling. Summary report[Final summary report

    Energy Technology Data Exchange (ETDEWEB)

    Frandsen, Steen; Barthelmie, R.; Rathmann, O.; Joergensen, Hans E.; Badger, J.; Hansen, Kurt; Ott, S.; Rethore, P.-E.; Larsen, Soeren E.; Jensen, Leo E.

    2007-07-15

    It was the goal of the project by means of data from the demonstration wind farms Horns Rev and Nysted, analyses of these data and modelling to facilitate prediction of the power losses from a wind farm should a new wind farm be built upwind relative to the prevailing wind direction. Or conversely, predict with adequate accuracy the production of a new wind farm built downwind of an existing wind farm. The project should be seen in the perspective of the two existing demonstration wind farms that extend 5-10 km in each direction. In order to e.g. use the existing electrical infrastructure it may be appropriate to build new wind farms rather close to the existing wind farms. A relevant question is therefore how far away new wind farms must be placed to avoid too large power losses. Measurements have been carried out for several years at the two sites, and databases have been prepared. The databases one for each site include production and operational statistics for the wind turbines and statistics for the meteorological measurements carries out in the vicinity of the wind farms. Several different modelling activities were carried out, which intentionally to some extent are redundant. Thus, if different modelling efforts results in comparable results, the quality of the models will be tested outside the physical range where data are available. All project participants find that the project has been immensely successful. The main achievements of the project are: 1) Measurements were carried out at the Nysted and Horns Rev demonstration wind farms for several years. Doing so included design, installation and operation of the measurement system 2) A data base was built from the incoming data. The data have been organized to facilitate verification of the models developed as part of the project 3) 6-7 different models have been developed and compared. 4) Approximately 20 journal and conference papers have resulted directly from the project (au)

  16. Pulmonary vasculitis may obscure large cell lung carcinoma. A case report

    NARCIS (Netherlands)

    Kreeftenberg, HG; Ligtenberg, JJM; van der Werf, TS; Timens, W; Tervaert, JWC

    2001-01-01

    Several vasculitic syndromes are recognized as paraneoplastic symdromes of an underlying malignant disease. Most frequently small vessel vasculitis of the skin has been reported. We describe the case of a 62-year-old man with a pulmonary mass due to pulmonary vasculitis. After resection of the pulmo

  17. Large-scale analysis of membrane transport in yeast using invertase reporters.

    Science.gov (United States)

    Dalton, Lauren; Davey, Michael; Conibear, Elizabeth

    2015-01-01

    Transport of membrane proteins between cellular organelles requires the concerted action of many regulatory factors, which aid in cargo recognition and vesicle formation, targeting, and fusion. The yeast Saccharomyces cerevisiae is a useful model system for studying such regulators, due to the availability of genome-wide mutant collections and reporter proteins that provide sensitive biochemical readouts of individual transport pathways. Here, we describe an enzymatic invertase assay for evaluating endocytic recycling using a chimeric GFP-Snc1-Suc2 reporter. Cell surface levels of this reporter can be measured by a colorimetric assay that monitors sucrose hydrolysis at the plasma membrane, using two different methods. The first is a semiquantitative agar overlay assay followed by image densitometry that is suitable for high-throughput screening of arrayed yeast colonies. In the second, more quantitative assay, an enzymatic solution is added to yeast cultures in a multi-well plate and the absorbance is assessed by a plate reader. Furthermore, the modular nature of the chimeric reporter allows alternate transport signals to be introduced, thereby expanding the range of transport pathways that can be evaluated by this method. Together these techniques can be used to explore the function of genes involved in a variety of cellular trafficking pathways.

  18. Pulmonary vasculitis may obscure large cell lung carcinoma. A case report

    NARCIS (Netherlands)

    Kreeftenberg, HG; Ligtenberg, JJM; van der Werf, TS; Timens, W; Tervaert, JWC

    2001-01-01

    Several vasculitic syndromes are recognized as paraneoplastic symdromes of an underlying malignant disease. Most frequently small vessel vasculitis of the skin has been reported. We describe the case of a 62-year-old man with a pulmonary mass due to pulmonary vasculitis. After resection of the

  19. Large Bladder Clot-An Unusual Presentation of Neonatal Bilateral Renal Vein Thrombosis-Case Report and Review of Literature.

    Science.gov (United States)

    Bandari, Jathin; Dangle, Pankaj P; Tennyson, Lauren E; Correa, Andres F; Cannon, Glenn M

    2015-10-01

    A 1-day-old boy born at 37 weeks gestation presented with hematuria, thrombocytopenia, and palpable irregular right flank mass. Renal ultrasound demonstrated large clot within the bladder, bilateral kidney masses with loss of corticomedullary differentiation, and reversal of diastolic flow. The patient was diagnosed with bilateral renal vein thrombosis and was managed conservatively. There was complete resolution of the bladder clot with restoration of corticomedullary differentiation bilaterally. We report the first case of renal vein thrombosis associated with a large bladder clot in a neonate.

  20. Workshop report on large-scale matrix diagonalization methods in chemistry theory institute

    Energy Technology Data Exchange (ETDEWEB)

    Bischof, C.H.; Shepard, R.L.; Huss-Lederman, S. [eds.

    1996-10-01

    The Large-Scale Matrix Diagonalization Methods in Chemistry theory institute brought together 41 computational chemists and numerical analysts. The goal was to understand the needs of the computational chemistry community in problems that utilize matrix diagonalization techniques. This was accomplished by reviewing the current state of the art and looking toward future directions in matrix diagonalization techniques. This institute occurred about 20 years after a related meeting of similar size. During those 20 years the Davidson method continued to dominate the problem of finding a few extremal eigenvalues for many computational chemistry problems. Work on non-diagonally dominant and non-Hermitian problems as well as parallel computing has also brought new methods to bear. The changes and similarities in problems and methods over the past two decades offered an interesting viewpoint for the success in this area. One important area covered by the talks was overviews of the source and nature of the chemistry problems. The numerical analysts were uniformly grateful for the efforts to convey a better understanding of the problems and issues faced in computational chemistry. An important outcome was an understanding of the wide range of eigenproblems encountered in computational chemistry. The workshop covered problems involving self- consistent-field (SCF), configuration interaction (CI), intramolecular vibrational relaxation (IVR), and scattering problems. In atomic structure calculations using the Hartree-Fock method (SCF), the symmetric matrices can range from order hundreds to thousands. These matrices often include large clusters of eigenvalues which can be as much as 25% of the spectrum. However, if Cl methods are also used, the matrix size can be between 10{sup 4} and 10{sup 9} where only one or a few extremal eigenvalues and eigenvectors are needed. Working with very large matrices has lead to the development of

  1. Improved Structure and Fabrication of Large, High-Power KHPS Rotors - Final Scientific/Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Corren, Dean [Verdant Power, Inc.; Colby, Jonathan [Verdant Power, Inc.; Adonizio, Mary Ann [Verdant Power, Inc.

    2013-01-29

    Verdant Power, Inc, working in partnership with the National Renewable Energy Laboratory (NREL), Sandia National Laboratories (SNL), and the University of Minnesota St. Anthony Falls Laboratory (SAFL), among other partners, used evolving Computational Fluid Dynamics (CFD) and Finite Element Analysis (FEA) models and techniques to improve the structure and fabrication of large, high-power composite Kinetic Hydropower System (KHPS) rotor blades. The objectives of the project were to: design; analyze; develop for manufacture and fabricate; and thoroughly test, in the lab and at full scale in the water, the improved KHPS rotor blade.

  2. Two Successful Term Pregnancies with a Large Descending Aorta Aneurysm: Case Report

    Directory of Open Access Journals (Sweden)

    Saghar Salehpour

    2008-12-01

    Full Text Available Aortic aneurysm is a rare but potentially lethal complication during pregnancy. In this article we described a 30-year-old woman with a large size descending aorta aneurysm (11 cm in length and 5.6 cm in its greatest diameter, who had two term uncomplicated pregnancies. The patient received prophylactic ß-blocker drug during her second pregnancy. Both pregnancies were terminated by caesarean section without any serious complications. Postpartum period was recovered successfully, but a noticeable increase in aneurysm’s length was detected in the period between two pregnancies.

  3. Laparoendoscopic Single-Site Surgery (LESS for a Large Ovarian Tumour: First Clinical Case Report

    Directory of Open Access Journals (Sweden)

    Yao Dong Chua

    2011-01-01

    Main Outcome Measure(s. Conversion to standard laparoscopic technique or laparotomy, estimated blood loss, operative time , extent of scarring, occurrence of intra- and perioperative surgical complications, technical adequacy, and clinical outcome. Result(s. No conversion to standard laparoscopic technique or laparotomy, and no intraoperative or postoperative complications were observed. Total operative time was 99 minutes. The patient was discharged home on postoperative day one. Conclusion(s. Laparoendoscopic single-site bilateral salpingo-oophorectomy of a large ovarian tumour is feasible with standard laparoscopic instruments. It is safe and effective, with good results in terms of excellent cosmesis and minimal postoperative pain.

  4. Two-hole trephination (Muntarbhorn) technique for a large frontal sinus osteoma: a case report.

    Science.gov (United States)

    Thanaviratananich, Sanguansak; Kasemsiri, Pornthep; Sinawat, Poonsiri

    2012-11-01

    To present an alternative surgical option for frontal sinus osteoma. A woman presented with a symptomatic large osteoma in right frontal sinus. Two-hole trephination was planned to remove the osteoma using nasal endoscope and a drill in each hole. The osteoma was drilled and removed transnasally. Two months later, two small fragments of osteoma were detected remaining in the lateral aspect of the sinus. The fragments were removed successfully with the same technique. The patient was asymptomatic six months postoperatively. Two-hole trephination technique or Muntarbhorn technique is an attractive option for frontal sinus osteoma.

  5. Unusually Large Peripheral Osteoma of the Mandible – A Rare Case Report

    Science.gov (United States)

    Dhupar, Vikas; Akkara, Francis

    2016-01-01

    Osteoma is a benign tumor which is composed of mature compact or cancellous bone. Osteoma may be periosteal (arising from surface of the bone) or endosteal (develop in the medullary bone) or combination of both. Here, we present a case of unusually large osteoma present on the lingual surface of the mandible in a 40-year-old female patient. The lesion had grown slowly for 15 years and caused intra-oral swelling leading to difficulty in mastication, speech and tongue movements. Under general anesthesia, local complete surgical excision was performed. PMID:28050514

  6. The V1 Population Gains Normalization

    NARCIS (Netherlands)

    Ganmor, Elad; Okun, Michael; Lampl, Ilan

    2009-01-01

    In this issue of Neuron, Busse et al. describe the population response to superimposed visual stimuli while Sit et al. examine the spatiotemporal evolution of cortical activation in response to small visual stimuli. Surprisingly, these two studies of V1 report that a single gain control model accoun

  7. Exploratory Factor Analysis of Self-Reported Symptoms in a Large, Population-Based Military Cohort

    Science.gov (United States)

    2010-10-15

    requiring dialysis, lupus, and Crohn’s disease. In order to mitigate potential biases in correlation estimates, those who endorsed all 39 medical diagnosis ...55,020 participants who completed the first follow-up survey, the 34 individuals who endorsed all 39 self-reported medical diagnosis questions and the...analysis suggests that it could be a manifestation of it or another condition associated with anxiety such as fibromyalgia [33]. Factor 3

  8. Large area silicon sheet by EFG. Annual progress report, October 29, 1975--September 30, 1976

    Energy Technology Data Exchange (ETDEWEB)

    Morrison, A.D.; Ravi, K.V.; Hari Rao, C.V.; Surek, T.; Bliss, D.F.; Garone, L.C.; Hogencamp, R.W.

    1976-09-15

    At the end of one year the program is on schedule. EFG ribbon growth system JPL No. 2 is being used to perform meaningful growth rate and ribbon thickness experiments. The new, wide ribbon growth system is in operation. A theoretical study of stresses in ribbons is reported. EFG ribbons have been observed to exhibit a characteristic defect structure which is orientation dependent in the early stages of growth.

  9. Cost optimizing of large-scale offshore wind farms. Appendix E to J. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This Volume 3 contains reports prepared by SEAS Distribution A.m.b.A. and partly by Risoe National Laboratory. Appendix E: Grid connection. Appendix F: Review of potential offshore sites. Appendix G: Optimisation of wind farm layout. Appendix G.1: Evaluation of Power Production from Three Offshore Wind Farms. Appendix H: Investments, operation and maintenance costs. Appendix I: Authority approvals and environmental investigations. Appendix J: Outline description of demonstration project. Appendix G.1 has been prepared by Risoe National Laboratory. (au)

  10. Ordered and Unordered Top-K Range Reporting in Large Data Sets

    DEFF Research Database (Denmark)

    Afshani, Peyman; Brodal, Gerth Stølting; Zeh, Norbert

    2011-01-01

    We study the following problem: Given an array A storing N real numbers, preprocess it to allow fast reporting of the K smallest elements in the subarray A[i, j] in sorted order, for any triple (i, j,K) with 1 ≤ i ≤ j ≤ N and 1 ≤ K ≤ j − i + 1. We are interested in scenarios where the array A is ...

  11. Online Monitoring Technical Basis and Analysis Framework for Large Power Transformers; Interim Report for FY 2012

    Energy Technology Data Exchange (ETDEWEB)

    Nancy J. Lybeck; Vivek Agarwal; Binh T. Pham; Heather D. Medema; Kirk Fitzgerald

    2012-09-01

    The Light Water Reactor Sustainability program at Idaho National Laboratory (INL) is actively conducting research to develop and demonstrate online monitoring (OLM) capabilities for active components in existing Nuclear Power Plants. A pilot project is currently underway to apply OLM to Generator Step-Up Transformers (GSUs) and Emergency Diesel Generators (EDGs). INL and the Electric Power Research Institute (EPRI) are working jointly to implement the pilot project. The EPRI Fleet-Wide Prognostic and Health Management (FW-PHM) Software Suite will be used to implement monitoring in conjunction with utility partners: the Shearon Harris Nuclear Generating Station (owned by Duke Energy for GSUs, and Braidwood Generating Station (owned by Exelon Corporation) for EDGs. This report presents monitoring techniques, fault signatures, and diagnostic and prognostic models for GSUs. GSUs are main transformers that are directly connected to generators, stepping up the voltage from the generator output voltage to the highest transmission voltages for supplying electricity to the transmission grid. Technical experts from Shearon Harris are assisting INL and EPRI in identifying critical faults and defining fault signatures associated with each fault. The resulting diagnostic models will be implemented in the FW-PHM Software Suite and tested using data from Shearon-Harris. Parallel research on EDGs is being conducted, and will be reported in an interim report during the first quarter of fiscal year 2013.

  12. Capillary gas chromatographic analysis of nerve agents using large volume injections. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Deinum, T.; Nieuwenhuy, C.

    1994-11-01

    The procedure developed at TNO-Prins Maurits Laboratory (TNO-PML) for the verification of intact organophosphorus chemical warfare agents in water samples was improved. The last step in this procedure, the laborious and non-reproducible transfer of an ethyl acetate extract onto a Tenax-adsorption tube followed by thermal desorption of the Tenax-tube, was replaced by large volume injection of the extract onto a capillary gas chromatographic system. The parameters controlling the injection of a large volume of an extract (200 ul) were investigated and optimized. As ethyl acetate caused severe problems, potential new solvents were evaluated. With the improved procedure, the nerve agents sarin, tabun, soman, diisopropyl fluorophosphate (DFP) and VX could be determined in freshly prepared water samples at pg/ml (ppt) levels. The fate of the nerve agents under study in water at two pH`s (4.8 and 6) was investigated. For VX, the pH should be adjusted before extraction. Moreover, it is worthwhile to acidify water samples to diminish hydrolysis.

  13. Diode Laser Diagnostics for Gas Species and Soot in Large Fires: LDRD Project Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Christopher R. Shaddix; Sarah W. Allendorf; Gary L. Hubbard; David K. Ottesen; Louis A. Gritzo

    2001-06-01

    The thermal hazard posed by a fire to a weapon or other engineered system is a consequence of combined radiation and convection from high-temperature soot and gases. The development of advanced, predictive models of this hazard requires detailed knowledge of the transient chemical structure and soot distributions within real-scale fires. At present, there are no measurements, and hence limited understanding, of transient gaseous species generation and transport in large, fully turbulent fires. As part of a Laboratory Directed Research and Development (LDRD) project to develop such an experimental capability, near-infrared tunable diode laser absorption spectroscopy (TDLAS) has been identified as the most promising diagnostic technique for making these measurements. In order to develop this capability, significant efforts were applied to choosing optimal species and transitions for detection, to developing an effective multiplexing strategy for several lasers undergoing wavelength modulation spectroscopy with fast laser ramp scans, to developing a methodology for multipassing the TDL beams across a small probe volume, and finally, to designing a water-cooled, fiber-coupled probe for performing these measurements locally within large pool fires. All of these challenges were surmounted during the course of this project, and in the end a preliminary, unique dataset of combined water vapor, acetylene, and soot concentrations was obtained from a 1-m diameter JP-8 pool fire.

  14. Bovine pericardium in treating large corneal perforation secondary to alkali injury: A case report

    Science.gov (United States)

    Mokhtar, Ezanee

    2008-01-01

    To describe use of a locally processed bovine pericardium (BP) to cover a large central corneal perforation following alkali injury and discuss postoperative outcome. A 27-year-old Malay male patient presented two weeks after alkali splashed in his left eye while working. A clinical diagnosis of left central corneal ulcer with limbal ischemia following alkali injury with secondary infection was made. After failed medical therapy, we performed a Gunderson conjunctival flap under local anesthesia that retracted after one week and resulted in a large central corneal perforation with surrounding stromal thinning. The perforation was covered with a locally processed BP xenograft (Lyolemb) supplied by the National Tissue Bank, University Sains Malaysia. Nine months follow-up showed a well-taken graft without any exposure/dehiscence and minimal inflammation. Amniotic membrane transplantation when used as a patch graft needs an urgent tectonic graft to promote corneal stability in patients with severe corneal thinning. The use of processed BP can be a viable option in treating such cases. PMID:18711278

  15. Cross-flow turbines: progress report on physical and numerical model studies at large laboratory scale

    Science.gov (United States)

    Wosnik, Martin; Bachant, Peter

    2016-11-01

    Cross-flow turbines show potential in marine hydrokinetic (MHK) applications. A research focus is on accurately predicting device performance and wake evolution to improve turbine array layouts for maximizing overall power output, i.e., minimizing wake interference, or taking advantage of constructive wake interaction. Experiments were carried with large laboratory-scale cross-flow turbines D O (1 m) using a turbine test bed in a large cross-section tow tank, designed to achieve sufficiently high Reynolds numbers for the results to be Reynolds number independent with respect to turbine performance and wake statistics, such that they can be reliably extrapolated to full scale and used for model validation. Several turbines of varying solidity were employed, including the UNH Reference Vertical Axis Turbine (RVAT) and a 1:6 scale model of the DOE-Sandia Reference Model 2 (RM2) turbine. To improve parameterization in array simulations, an actuator line model (ALM) was developed to provide a computationally feasible method for simulating full turbine arrays inside Navier-Stokes models. Results are presented for the simulation of performance and wake dynamics of cross-flow turbines and compared with experiments and body-fitted mesh, blade-resolving CFD. Supported by NSF-CBET Grant 1150797, Sandia National Laboratories.

  16. Report on the development of the large-bore powder gun for the Nevada Test Site

    Energy Technology Data Exchange (ETDEWEB)

    B.J. Jensen

    2009-03-01

    Experiments are needed to locate phase boundaries and to provide both Hugoniot data and off-Hugoniot data (such as principle isentrope, refreezing, dynamic strength, etc.) achieved through complex loading paths. The objective of the current work was to de- velop a large bore (3.5 inch or greater) powder gun capable of accelerating projectiles to moderately high velocities exceeding 2 km/s for impact experiments. A total of 24 ex- periments were performed to measure the projectile velocity, breech strain, and projectile tilt to demonstrate the performance of the gun up to the maximum breech capacity of 16 pounds of propellant. Physics experiments using a multislug method were performed to obtain sound speed and Hugoniot for shocked cerium metal and to demonstrate the ability of the large bore gun to conduct well-defined, plate-impact experiments. In addition, six experiments were performed on the prototype containment system to examine the ability of the launcher and containment system to withstand the impact event and contain the propellant gases and impact debris postshot. The data presented here were essential for qualification of the launcher for experiments to be conducted at the U1a complex of the Nevada Test Site.

  17. Large-Scale Digital Geologic Map Databases and Reports of the North Coal District in Afghanistan

    Science.gov (United States)

    Hare, Trent M.; Davis, Philip A.; Nigh, Devon; Skinner, James A.; SanFilipo, John R.; Bolm, Karen S.; Fortezzo, Corey M.; Galuszka, Donna; Stettner, William R.; Sultani, Shafiqullah; Nader, Billal

    2008-01-01

    This report describes the Afghanistan coal resource maps and associated databases that have been digitally captured and maps that have been thus far converted to GIS databases. Several maps by V/O Technoexport, USSR (VOTU) and Bundesanstalt fur Bodenforschung (BGR), Hannover, Germany, are captured here. Most of the historical coal exploration is concentrated in north-central Afghanistan, a region referred to as the 'North Coal District', and almost all of the coal-related maps found Afghanistan Geological Survey (AGS) archives to date cover various locations within that district as shown in the index map. Most of the maps included herein were originally scanned during U.S. Geological Survey (USGS) site visits to Kabul in November 2004 and February 2006. The scanning was performed using equipment purchased by U.S. Agency for International Development (USAID) and U.S. Trade and Development Agency (USTDA) and installed at the AGS by USGS. Many of these maps and associated reports exist as single unpublished copies in the AGS archives, so these efforts served not only to provide a basis for digital capturing, but also as a means for preserving these rare geologic maps and reports. The data included herein represent most of the coal-related reports and maps that are available in the AGS archives. This report excludes the limited cases when a significant portion of a report's text could not be located, but it does not exclude reports with missing plates. The vector files are released using the Environmental Systems Research Institute (ESRI) Personal Geodatabase, ESRI shapefile vector format, and the open Geography Markup Language (GML) format. Scanned images are available in JPEG and, when rectified, GeoTIFF format. The authors wish to acknowledge the contributions made by the staff of the AGS Records and Coal Departments whose valuable assistance made it possible to locate and catalogue the data provided herein. We especially acknowledge the efforts of particular

  18. Capital Gains Taxation and House Price Fluctuations

    DEFF Research Database (Denmark)

    Fuest, Clemens; Nielsen, Søren Bo

    2004-01-01

    Recent years have seen large swings in house prices in many countries. Motivated by housing price variations, proposals for taxing capital gains on housing have repeatedly been put forth. The idea seems to be that such taxes would curb the redistribution occurring between those owning houses...... and those trying to get into the market for owner-occupied housing. Our paper shows that at least in simple settings, a tax on real capital gains on housing will only lead to even bigger price swings and will not be able to redistribute between people appearing on either side of the housing market.......Keywords: capital gains tax, housing market, price fluctuationsJEL-Classification: H23, H24, R 31.Addresses:...

  19. MRI induced second-degree burn in a patient with extremely large uterine leiomyomas: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Chul Min; Kang, Bo Kyeong; Song, Soon Young; Koh, Byung Hee; Choi, Joong Sub; Lee, Won Moo [Hanyang University Medical Center, Hanyang University College of Medicine, Seoul (Korea, Republic of)

    2015-12-15

    Burns and thermal injuries related with magnetic resonance imaging (MRI) are rare. Previous literature indicates that medical devices with cable, cosmetics or tattoo are known as risk factors for burns and thermal injuries. However, there is no report of MRI-related burns in Korea. Herein, we reported a case of deep second degree burn after MRI in a 38-year-old female patient with multiple uterine leiomyomas including some that were large and degenerated. The large uterine leiomyoma-induced protruded anterior abdominal wall in direct contact with the body coil during MRI was suspected as the cause of injury, by retrospective analysis. Therefore, awareness of MRI related thermal injury is necessary to prevent this hazard, together with extreme care during MRI.

  20. Large cell neuroendocrine cervical tumor treated by radical surgery and adjuvant chemotherapy: A case report and literature review.

    Science.gov (United States)

    BacalbaȘa, Nicolae; Stoica, Claudia; Marcu, Madalina; Mihalache, Daniela; Vasilescu, Florina; Popa, Ileana; Mirea, Gratiela; Bălescu, Irina

    2016-01-01

    Neuroendocrine carcinomas of the uterine cervix are rare, but extremely aggressive, gynecological malignancies that are associated with an overall poor prognosis. The present study reports the case of a 41-year-old patient diagnosed with large cell neuroendocrine cervical tumor. A radical total hysterectomy with bilateral adnexectomy, pelvic and lymph node dissection was performed. The post-operative course was uneventful, and the patient was discharged on post-operative day 8.

  1. Obtaining large-scale funding for empowerment-oriented qualitative research: a report from personal experience.

    Science.gov (United States)

    Padgett, Deborah K; Henwood, Benjamin F

    2009-06-01

    Obtaining funding for qualitative research remains a challenge despite greater openness to methodological pluralism. Such hurdles are presumably compounded when the proposed study employs empowerment theory, rendering it susceptible to charges of elevating ideology over rigor. This article draws on the authors' experience in securing large-scale funding for an empowerment-oriented qualitative study of homeless mentally ill adults. Lessons learned include the importance of weaving empowerment theory into the proposal's "argument," and infusing empowerment values into study protocols while simultaneously paying close attention to rigorous and transparent methods. Additional benefits accrue from having prior relationships with study sites and being willing to revise and resubmit proposals whenever possible. Though representing a fraction of all externally funded projects in the United States, qualitative research has tremendous untapped potential for success in this competitive arena-success that need not entail surrendering a commitment to empowerment values.

  2. Improved design of large wind turbine blades of fibre composites (Phase 2) - Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Soerensen, B.F. [Risoe National Lab., Materials Research Dept., Roskilde (Denmark); Branner, K. [Risoe National Lab., Wind Energy Dept., Roskilde (Denmark); Stang, H. [Technical Univ. of Denmark, Dept. of Civil Engineering, Kgs. Lyngby (Denmark); Jensen, H.M. [Aalborg Univ., Dept. of Building Technology and Structural Engineering (Denmark); Lund, E. [Aalborg Univ., Inst. of Mechanical Enginering (Denmark); Jacobsen, T.K. [LM glasfiber A/S, Lunderskov (Denmark); Halling, K.M. [Vestas Wind Systems A/S, Ringkoebing (Denmark)

    2005-08-01

    The major results of Phase 2 of a project concerning the development of new design methods for wind turbine blades are summarised. Finite element models were used for studying the buckling behaviour of a box girder, tested to failure in Phase 1 of this project. The deformation behaviour of a box girder section subjected to transverse forces was investigated experimentally and by modelling. Buckling-driven delamination of planar specimens was studied on experimentally and by modelling. A novel approach was proposed for the determination of mixed mode cohesive laws for large-scale crack bridging problems. The normal and shear stresses of the cohesive laws were obtained from data of the fracture resistance and the normal and tangential displacements of the cohesive zone. Delamination of a thin layer bonded to an elastic substrate close to corners and edges was also analysed. Results for the shape of the interface crack front and critical stress for steady-state delamination were obtained. (au)

  3. Primary pancreatic anaplastic large cell lymphoma, ALK negative:A case report

    Institute of Scientific and Technical Information of China (English)

    Christos G Savopoulos; NE Tsesmeli; GD Kaiafa; AT Zantidis; MT Bobos; AI Hatzitolios; ST Papavramidis; IS Kostopoulos

    2005-01-01

    We present the fourth case of a primary pancreatic anaplastic large cell lymphoma (ALCL), ALK-. An 80-year-old man was admitted to our clinic for further investigation of a fever of unknown origin. He noted anorexia, weight loss and fatigue. His laboratory tests showed anemia and a great elevation of ESR, LDH, and β2 microglobulin. In CT and MRI scan, a soft tissue mass in the pancreas was observed. A repeated endoscopy after his admission revealed an ulcerated mass-like deformity of the duodenal bulb. Explorative laparotomy confirmed a diffuse spread of an unresectable malignant pancreatic mass extending to the adjacent organs. Duodenal and surgical biopsies identified an ALCL of T-cell lineage, ALK-. The patient died in the Intensive Care Unit due to hemodynamic instability.Our case is the first one indicating that primary pancreatic lymphoma should be suspected in a patient with pancreatic mass and elevated serum LDH and β2 microglobulin.

  4. [Sequencing by hybridization methods to generate large arrays of oligonucleotides]. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    The subject of this project is to address a pressing need for custom DNA microarrays (chips) which can be easily and at low cost formatted and revised for research. In this sense, the term custom means chips for which there is need for limited quantities (less than hundreds) of any particular chip design which contains a large number of different, users defined sequences. Of the three principal approaches to fabricate DNA microarrays, the two which have been commercialized (a and b below) are not particularly suited to research purposes because of the significant time and costs required, once a result is obtained, to utilize that result in the design of a new and better chip: (a) the photodeprotection scheme used by Affymetrix; and (b) the spotting of pre-synthesized oligos or c-DNA onto surfaces.

  5. Final report. Human artificial episomal chromosome (HAEC) for building large genomic libraries

    Energy Technology Data Exchange (ETDEWEB)

    Jean-Michael H. Vos

    1999-12-09

    Collections of human DNA fragments are maintained for research purposes as clones in bacterial host cells. However for unknown reasons, some regions of the human genome appear to be unclonable or unstable in bacteria. Their team has developed a system using episomes (extrachromosomal, autonomously replication DNA) that maintains large DNA fragments in human cells. This human artificial episomal chromosomal (HAEC) system may prove useful for coverage of these especially difficult regions. In the broader biomedical community, the HAEC system also shows promise for use in functional genomics and gene therapy. Recent improvements to the HAEC system and its application to mapping, sequencing, and functionally studying human and mouse DNA are summarized. Mapping and sequencing the human genome and model organisms are only the first steps in determining the function of various genetic units critical for gene regulation, DNA replication, chromatin packaging, chromosomal stability, and chromatid segregation. Such studies will require the ability to transfer and manipulate entire functional units into mammalian cells.

  6. Improved design for large wind turbine blades of fibre composites (Phase 3) - Summary report

    Energy Technology Data Exchange (ETDEWEB)

    Soerensen, B.F. (Risoe DTU, Materials Research Div., Roskilde (Denmark)); Branner, K. (Risoe DTU, Wind Energy Div., Roskilde (Denmark)); Lund, E. (Aalborg Univ., Dept. of Mechanical Engineering, Aalborg (Denmark)); Wedel-Heinen, J. (Vestas Wind System, Randers (Denmark)); Garm, J.H. (LM Glasfiber, Kolding (Denmark))

    2009-06-15

    An overview is given of the activities of the project 'Improved design for large wind turbine blades (Phase 3)', partially supported by the Danish Energy Agency under the Ministry of Climate and Energy through the EFP-grant no. 33031-0078. The project was focussed at the development of new design methods for wind turbine blades, so that uncertainties associated with damage and defects can be reduced. The following topics with respect to failure modes were covered: Buckling-driven delamination of load-carrying laminates, cracking along interfaces in material joints, implementation of cohesive laws in finite element programmes and hierarchical finite element models. Methods and major research results of the project are summarised. Some future goals for future research activities are briefly discussed. (author)

  7. Ordered and Unordered Top-K Range Reporting in Large Data Sets

    DEFF Research Database (Denmark)

    Afshani, Peyman; Brodal, Gerth Stølting; Zeh, Norbert

    2011-01-01

    A is large, necessitating an I/O-efficient solution. For a parameter f with 1 ≤ f ≤ logm n, we construct a data structure that uses O((N/f) logm n) space and achieves a query bound of O(logB N + fK/B) I/Os,1 where B is the block size, M is the size of the main memory, n := N/B, and m := M/B. Our main...... contribution is to show that this solution is nearly optimal. To be precise, we show that achieving a query bound of O(logα n + fK/B) I/Os, for any constant α, requires ΩN f−1 logM n log(f−1 logM n) space, assuming B = Ω(logN). ForM ≥ B1+ε, this is within a log logm n factor of the upper bound. The lower bound...

  8. A Large-Grain Data Flow scheduler for scientific parallel processing: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Babb, R.G. II; DiNucci, D.C.

    1988-09-16

    The work accomplished on the contract can be summarized as follows: used LGDF to model the high level work allocation portion of an ITSM physics code; modeled the lower level synchronization portions of ITSM physics codes and developed a new parallelization strategy; and developed a new version of LGDF, called LGDF 2, that is better equipped to handle such applications as ITSM physics codes, and implemented an LGDF 2 scheduler for the Sequent. This report covers each of these three areas. 7 refs., 5 figs.

  9. ALK-positive anaplastic large cell lymphoma presenting as intradural spinal mass: first reported case and review of literature.

    Science.gov (United States)

    Novello, Mariangela; Lauriola, Libero; Della Pepa, Giuseppe Maria; Giuseppe, La Rocca; Coli, Antonella; Visocchi, Massimiliano

    2013-08-01

    Anaplastic large cell lymphoma (ALCL) is characterized by large anaplastic cells of T-cell or null-cell phenotype expressing CD30 (Ki-1 antigen). In most cases this neoplasm expresses the anaplastic lymphoma kinase (ALK), a chimeric protein resulting from the t(2;5)(p23;q35) translocation. ALK-positive anaplastic large cell lymphoma is most frequent in the first three decades of life and shows a male predominance, involving both nodal and extranodal sites, but rarely the CNS. We report a 21-year-old patient with a previous history of nodal ALK-positive ALCL, lymphohistiocytic subtype, who was admitted for recent occurrence of left-sided anesthesia with pain and progressive motor weakness of both legs. An MRI of the spine documented an intradural extramedullary mass dislocating the thoracic cord, suggesting a meningioma and the patient underwent surgical decompression. Histological examination revealed a lymphoproliferative neoplasm with morphology and immunophenotype of ALK-positive anaplastic large cell lymphoma. After surgery, all preoperative symptoms disappeared. To our knowledge, no cases of ALCL presenting as secondary localization with an intradural extramedullary spinal mass have been reported in the literature. © 2012 Japanese Society of Neuropathology.

  10. Concomitant sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease and diffuse large B-cell lymphoma: a case report

    Directory of Open Access Journals (Sweden)

    Moore James C

    2008-03-01

    Full Text Available Abstract Introduction Sinus histiocytosis with massive lymphadenopathy, also known as Rosai-Dorfman Disease, is a rare and benign source of lymphadenopathy first described in 1969, which mimics neoplastic processes. This disease commonly presents in children and young adults with supra-diaphragmatic lymphadenopathy or extranodal lesions consisting of tissue infiltrates composed of a polyclonal population of histiocytes. Since its description greater than 400 cases have been described, sometimes in patients with a variety of treated and untreated neoplastic diseases. However, the literature contains reports of only 19 cases of Rosai-Dorfman Disease in association with lymphomas, Hodgkin's or non-Hodgkin's. The majority of these cases have the two diagnoses, malignant lymphoma and Rosai-Dorfman Disease, separated in time. Interestingly, infradiaphragmatic lymphadenopathy was a feature in the majority of previously reported cases of Rosai-Dorfman Disease and non-Hodgkin's lymphoma. Case presentation This report provides details of a case with co-existing sinus histiocytosis with massive lymphadenopathy and diffuse large B cell non-Hodgkin's lymphoma. This case is the fifth described case of simultaneous Rosai-Dorfman Disease and concurrent non-Hodgkin's lymphoma. Unfortunately, the diagnosis of a clinically aggressive diffuse large B cell lymphoma was made at autopsy. The aggressive biological behavior of the diffuse large B cell lymphoma in this patient may have been related to the underlying immune dysregulation believed to be part of the pathophysiology of Rosai-Dorfman Disease. Conclusion Taken together this report and the preceding reports of Rosai-Dorfman Disease and non-Hodgkin's lymphoma suggests that in cases with a diagnosis of Rosai-Dorfman Disease in the setting of prominent infradiaphragmatic lymphadenopathy, clinicians should maintain a high index of suspicion for the presence of occult non-Hodgkin's lymphoma especially if the

  11. "Tent-Pole" for Reconstruction of Large Alveolar Defects: A Case Report.

    Science.gov (United States)

    Xiao, Ting; Zhao, Yuyue; Luo, En; Hu, Jian

    2016-01-01

    Severe tridimensional alveolar ridge defects complicate the placement of dental implants, and surgical removal of some oral tumors might not leave adequate bone for dental implant placement. Regenerating an adequate amount of bone vertically and horizontally to achieve a satisfying outcome for well-osseointegrated implants and thus ensure long-term success of implant restoration is challenging. This report describes the clinical feasibility of a simple approach using a screw tent-pole combined with guided bone regeneration to augment complicated tridimensional alveolar ridge defects in a case of extensive bone loss due to maxillary tumor surgery. Titanium screws were arranged in "tented" fashion to provide stable room for bone regeneration. Regenerated bone was achieved and 2 more implants were placed in the regenerated ridge 10 months later, leading to a successful maxillary prosthesis.

  12. IMPER: Characterization of the wind field over a large wind turbine rotor - final report; Improved performance

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt Paulsen, U.; Wagner, R.

    2012-01-15

    A modern wind turbine rotor with a contemporary rotor size would easily with the tips penetrate the air between 116 m and 30 m and herby experience effects of different wind. With current rules on power performance measurements such as IEC 61400-121 the reference wind speed is measured at hub height, an oversimplification of the wind energy power over the rotor disk area is carried out. The project comprised a number of innovative and coordinated measurements on a full scale turbine with remote sensing technology and simulations on a 500 kW wind turbine for the effects of wind field characterization. The objective with the present report is to give a short overview of the different experiments carried out and results obtained within the final phase of this project. (Author)

  13. Large bowel leiomyosarcoma - a case report; Leiomiosarcoma do intestino grosso - relato de um caso

    Energy Technology Data Exchange (ETDEWEB)

    Lopes, Simone Goncalves; Marchiori, Edson; Brick, Julieta Figueiredo; Curty Neto, Eduardo; Scherman, Alexandre; Silva, Ana Carina Gamboa da; Machado, Bruno Beber [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Radiologia]. E-mail: edmarchiori@zipmail.com.br

    2001-04-01

    The authors report a case of a 49-year-old male patient with leiomyosarcoma of the ascending colon. The patient presented with anemia and an abdominal mass, and the symptoms progressed until a final diagnosis was made nine months later. A plain abdominal x-ray showed the presence of gas outside the bowel, in the right hypochondrium. The double contrast barium enema showed a sublevel displacement of the hepatic flexure and diverticula. An abdominal ultrasound revealed a heterogeneous expansive lesion below the liver containing gas, and a computed tomography of the abdomen revealed an excavated mass below the liver containing liquid, that was not filled by contrast medium. The patient was submitted to a right hemicolectomy with ileocoloanastomosis and the histopathological analysis of the excised material revealed a leiomyosarcoma of the ascending colon. (author)

  14. Infantile multiple large pyogenic granuloma on burned skin. Case report and review of literature*

    Science.gov (United States)

    Dastgheib, Ladan; Maghami, Zohreh; Aslani, Fatemeh Sari

    2016-01-01

    Pyogenic granuloma (PG) is a benign vascular lesion of the skin and mucous membranes, presenting as a solitary, red, pedunculated papule that bleeds easily and which appears to be a reactive vascular proliferation to minor injury. These lesions are more common in children and are mostly seen in exposed sites. Multiple disseminated PG is a rare condition. This report describes an infant with multiple, disseminated, pyogenic granulomas following burns from boiling milk. We reviewed literature published in English and found 9 cases. Six cases were provoked by hot milk, 2 by hot water, while the cause of the other case is unknown. Angiogiogenetic activity in milk may explain PG development in these patients. PMID:27192522

  15. Large calcifying epithelial odontogenic tumor with extension into the maxillary sinus: a case report.

    Science.gov (United States)

    da Rosa, Marize Raquel Diniz; de Oliveira, James Maxwell Souza; Dias-Ribeiro, Eduardo; Ferreira-Rocha, Julierme; de Barros, Iolanda Maria Cariry Carvalho Lacet; Lopes, Patricia de Medeiros Loureiro

    2011-01-01

    Calcifying epithelial odontogenic tumor (CEOT) is a rare, locally invasive neoplasm characterized by the presence of amyloid material that can become calcified. It often is found in the posterior region of the mandible. Such tumors in the maxilla and those that invade the maxillary sinus are extremely rare. This article presents the sixth reported clinical case of a CEOT that invaded the maxillary sinus and extended to the interior of the nasal cavity. The tumor had grown toward the sinus roof, but there was no association with an impacted tooth. Histopathologically, the tumor was composed of plates of polyhedral epithelial cells with highly eosinoplilic cytoplasm, nuclear polymorphism, clear-cell contours, and intercellular bridges in fibrous conjunctive tissue. Amorphous eosinophilic material and diverse calcifications permeated the epithelial cells.

  16. High-Luminosity Large Hadron Collider (HL-LHC) Technical Design Report V. 0.1

    CERN Document Server

    Béjar Alonso I.; Brüning O.; Fessia P.; Lamont M.; Rossi L.; Tavian L.

    2017-01-01

    The Large Hadron Collider (LHC) is one of the largest scientific instruments ever built. Since opening up a newenergy frontier for exploration in 2010, it has gathered a global user community of about 7,000 scientists work-ing in fundamental particle physics and the physics of hadronic matter at extreme temperature and density. Tosustain and extend its discovery potential, the LHC will need a major upgrade in the 2020s. This will increase itsinstantaneous luminosity (rate of collisions) by a factor of five beyond the original design value and the integratedluminosity (total collisions created) by a factor ten. The LHC is already a highly complex and exquisitely opti-mised machine so this upgrade must be carefully conceived and will require about ten years to implement. Thenew configuration, known as High Luminosity LHC (HL-LHC), relies on a number of key innovations that pushaccelerator technology beyond its present limits. Among these are cutting-edge 11-12 tesla superconducting mag-nets, compact superco...

  17. High-Luminosity Large Hadron Collider (HL-LHC) Preliminary Design Report

    CERN Document Server

    Apollinari, G; Béjar Alonso, I; Brüning, O; Lamont, M; Rossi, L

    2015-01-01

    The Large Hadron Collider (LHC) is one of the largest scientific instruments ever built. Since opening up a new energy frontier for exploration in 2010, it has gathered a global user community of about 7,000 scientists working in fundamental particle physics and the physics of hadronic matter at extreme temperature and density. To sustain and extend its discovery potential, the LHC will need a major upgrade in the 2020s. This will increase its luminosity (rate of collisions) by a factor of five beyond the original design value and the integrated luminosity (total collisions created) by a factor ten. The LHC is already a highly complex and exquisitely optimised machine so this upgrade must be carefully conceived and will require about ten years to implement. The new configuration, known as High Luminosity LHC (HL-LHC), will rely on a number of key innovations that push accelerator technology beyond its present limits. Among these are cutting-edge 11-12 tesla superconducting magnets, compact superconducting cav...

  18. STATUS REPORT ON THE CMS FORWARD MUON UPGRADE WITH LARGE-SIZE TRIPLE-GEM DETECTORS

    CERN Document Server

    Barria, Patrizia

    2014-01-01

    For the LHC High Luminosity phase (HL-LHC) the CMS GEM Collaboration is planning to install new large size (990 x 440-220 mm2) triple-GEM detectors, equipped with a new readout system, in the forward region of the muon system (1.5 lt IηI lt 2.2) of the CMS detector. Combining triggering and tracking functionalities the new triple-Gas Electron Multiplier (GEM) chambers will not only improve the performance of the CMS muon trigger, but will also improve the muon identification and track reconstruction. With the addition of triple-GEM detectors the forward region of the CMS muon spectrometer will recover its originally planned redundancy. Starting from 2009 the CMS GEM Collaboration built several small and full size prototypes with different geometries, keeping improving the assembly techniques. All these prototypes have been tested in laboratories as well as with beam tests at the CERN SPS and at Fermilab. The results show that the triple-GEM detectors are a mature technology satisfying all the requirements ...

  19. A Report on Simulation-Driven Reliability and Failure Analysis of Large-Scale Storage Systems

    Energy Technology Data Exchange (ETDEWEB)

    Wan, Lipeng [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wang, Feiyi [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Oral, H. Sarp [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Vazhkudai, Sudharshan S. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Cao, Qing [Univ. of Tennessee, Knoxville, TN (United States)

    2014-11-01

    High-performance computing (HPC) storage systems provide data availability and reliability using various hardware and software fault tolerance techniques. Usually, reliability and availability are calculated at the subsystem or component level using limited metrics such as, mean time to failure (MTTF) or mean time to data loss (MTTDL). This often means settling on simple and disconnected failure models (such as exponential failure rate) to achieve tractable and close-formed solutions. However, such models have been shown to be insufficient in assessing end-to-end storage system reliability and availability. We propose a generic simulation framework aimed at analyzing the reliability and availability of storage systems at scale, and investigating what-if scenarios. The framework is designed for an end-to-end storage system, accommodating the various components and subsystems, their interconnections, failure patterns and propagation, and performs dependency analysis to capture a wide-range of failure cases. We evaluate the framework against a large-scale storage system that is in production and analyze its failure projections toward and beyond the end of lifecycle. We also examine the potential operational impact by studying how different types of components affect the overall system reliability and availability, and present the preliminary results

  20. Large area silicon sheet by EFG. Fourth quarterly report, October 1-December 31, 1978

    Energy Technology Data Exchange (ETDEWEB)

    Wald, F.V.

    1979-03-01

    Crystal growth station no. 1 further explored displaced die concepts, along with some initial work on buckle characterization. Also, convective impurity redistribution was further studied. In particular, a side channel die was used to grow material doped with aluminum and compare the results at least semiquantitatively with computer calculations. The ribbons grown have not been characterized yet. In station no. 3A growth from single cartridges was continued to create a quality baseline to allow comparison of the results with those in the upcoming multiple run and to choose the most appropriate die design. Also fabrication and assembly work on the actual five ribbon furnace continued. On furnace 17 progress was made toward the development of the video optical system for edge position and meniscus height control. Also, in preparation for a detailed program, designed to explore the buckling problem, ribbon width ribon was then grown under stable conditions without a cold shoe, an achievement essential to finally arrive at quantitative correlations between growth conditions and buckle formation. The most significant result from the characterization program was a demonstration that the original runs with displaced dies were indeed reproducible, inasmuch as large area cells (7.5 x 7.5 cm/sup 2/) of approx. 9% efficiency could be fabricated again from run 18-103, a repeat of run no. 18-102 which had previously produced the best cells.

  1. Large area silicon sheet by EFG. Annual progress report, October 1, 1977-September 30, 1978

    Energy Technology Data Exchange (ETDEWEB)

    Wald, F.V.

    1979-02-16

    Progress in EFG ribbon growth was made in a number of areas as follows: (1) Multiple growth for ribbons 5 cm in width was demonstrated in two runs of 12 and 20 hours' duration. (2) A new single cartridge crystal growth station, designated Machine 17, was built. It has vastly expanded observational capacity by virture of an anamorphic optical-video system which allows close observation of the meniscus over 7.5 cm in width, as well as video taping of the ribbon growth process for further analysis. Also, a number of mechanical advances were incorporated into this equipment. (3) Growth Station No. 1 achieved reproducible and reliable growth of 7.5 cm wide ribbon at speeds up to 4 cm/min. (4) A major advance in cartridge design, the mini cold shoe, was introduced. (5) Interface shaping using the displaced die concept led to significant increases in cell efficiency. Large area cells (2.5 by 7.5 cm/sup 2/, 2.5 x 10 cm/sup 2/, and 7.5 by 7.5 cm/sup 2/), which achieve efficiencies over 9%, have been made in significant numbers. (6) The role of gaseous impurities in cartridge furnaces has been clarified and their destabilizing influence on growth has been brought under control. Details of most of these developments are discussed.

  2. High-Luminosity Large Hadron Collider (HL-LHC) : Preliminary Design Report

    Energy Technology Data Exchange (ETDEWEB)

    Apollinari, G. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Béjar Alonso, I. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Brüning, O. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Lamont, M. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Rossi, L. [European Organization for Nuclear Research (CERN), Geneva (Switzerland)

    2015-12-17

    The Large Hadron Collider (LHC) is one of the largest scientific instruments ever built. Since opening up a new energy frontier for exploration in 2010, it has gathered a global user community of about 7,000 scientists working in fundamental particle physics and the physics of hadronic matter at extreme temperature and density. To sustain and extend its discovery potential, the LHC will need a major upgrade in the 2020s. This will increase its luminosity (rate of collisions) by a factor of five beyond the original design value and the integrated luminosity (total collisions created) by a factor ten. The LHC is already a highly complex and exquisitely optimised machine so this upgrade must be carefully conceived and will require about ten years to implement. The new configuration, known as High Luminosity LHC (HL-LHC), will rely on a number of key innovations that push accelerator technology beyond its present limits. Among these are cutting-edge 11-12 tesla superconducting magnets, compact superconducting cavities for beam rotation with ultra-precise phase control, new technology and physical processes for beam collimation and 300 metre-long high-power superconducting links with negligible energy dissipation. The present document describes the technologies and components that will be used to realise the project and is intended to serve as the basis for the detailed engineering design of HL-LHC.

  3. Homicide and subsequent catatonia associated with a large arachnoid cyst: case report.

    Science.gov (United States)

    Margetić, Branimir; Palijan, Tija Zarković; Kovacević, Drazen

    2013-12-01

    The existence of a focal brain lesion that might be the crucial cause for the development of diverse psychiatric phenomena and certain characteristics of personality is often a controversial issue. The patient was a 29-year-old male when he killed his father with a single knock with the blunt side of an axe. Subsequently to the act, the patient developed a 10-month-long catatonic stupor during which he experienced intensive fear, delusions, and affective symptoms. He was an emotionally blunted person with no medical record and without prior history of aggressive behavior. Magnetic resonance image revealed a large, right-sided arachnoid cyst that was associated with right temporal and frontal lobe hypoplasia and bilateral changes of perfusion in peri-insular regions. The treatment with clozapine and diazepam showed to be therapeutic. This could be the second case of homicide committed by a person with arachnoid cyst and without past history of aggression, and the second description of an adult patient with cyst who developed catatonic stupor. This is the first description of long-lasting organic catatonic stupor treated with clozapine and diazepam. Relevant literature is reviewed and some controversial issues are discussed.

  4. Preliminary Report On Combined Surgical- And Laser-Treatment Of Large Hemangiomas And Tattoos

    Science.gov (United States)

    Ginsbach, G.

    1981-05-01

    As most hemangiomas and tattoos require many sessions to be cured completely by argon-laser or conventional therapy I developed a new combined surgical and laser-therapy method for large hemangiomas and tattoos. This is a three step method. First: The skin lesion is treated by argon-laser with the point by point method, developed by ourself. Second: Under local or general anaesthesia a) the hemangioma is partially excised and undermined letting only the skin which is already treated by argon-laser-beams. Than the hemangioma is exstirpated in toto, the wound closed by running intradermal sutures and a pressure bandage applied, b) the tattoo is abraded as deep as possible, draped by lyofoam. Then a pressure bandage is applied. Third: The hemangioma as well as the tattoo are treated by argon-laser-beams after the operation. This method is safe and effective, gives good results, minimal scars in the case of hemangiomas and tattoos. In this paper the method is described and some cases are illustrated by pre- and postoperational photographs.

  5. CRADA/NFE-15-05779 Report: Fabrication of Large Area Printable Composite Magnets

    Energy Technology Data Exchange (ETDEWEB)

    Paranthaman, M. Parans [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-09-29

    The technical objective of this technical collaboration phase I proposal was to fabricate large area NdFeB composite magnets at the Oak Ridge National Laboratory Manufacturing Demonstration Facility (ORNL MDF). The goal was to distribute domestically produced isotropic and highly anisotropic high energy density magnetic particles throughout the composite structure in order to enable site specific placement of magnetic phases and minimize the generated waste associated with permanent magnet manufacturing. Big area additive manufacturing (BAAM) and magnet composite fabrication methods were used in this study. BAAM was used to fabricate 65 vol % isotropic MQP NdFeB magnets in nylon polymer matrix. BAAM magnet cylinder was sliced to two magnetic arc-shaped braces. The density of the small BAAM magnet pieces reached 4.1 g/cm3, and the room temperature magnetic properties are: Intrinsic coercivity Hci = 8.8 kOe, Remanence Br = 4.2 kG, and energy product (BH)max = 3.7 MGOe. Also, 1.5” x 1.5” composite magnets with anisotropic MQA NdFeB magnet in a resin were also fabricated under magnetic field. The unaligned sample had a density of 3.75 g/cm3. However, aligned sample possessed a density of 4.27 g/cm3. The magnetic properties didn’t degrade during this process. This study provides a pathway for preparing composite magnets for various magnetic applications.

  6. 200 city survey. JEMS 2001 annual report on EMS operational & clinical trends in large, urban areas.

    Science.gov (United States)

    Cady, Geoff

    2002-02-01

    This year's survey offered examples of evolving partnerships between the public and EMS providers with a growing number of systems implementing PAD programs. The apparent influence of a communication center's managing agency on prioritization strategies is concerning. However, further study is needed. EMS managers must pay careful attention to comm center practices and technology to ensure their ability to support response prioritization and the efficient management of EMS resources. The small reduction in the use of hot response (lights and siren) to every request for service is disappointing in light of medical literature and position statements that condemn this practice. Resource response can be safely prioritized using today's EMD protocol systems. Prioritization and changing response [figure: see text] time requirements to address impending revenue and service demand changes will require additional standardization of methodologies and reporting of response times to relate this measure to other system performance indicators (e.g., patient morbidity/mortality, cost, customer satisfaction, etc.). The future presents a difficult road for system administrators. However, the adoption of a growing number of information-management tools and changes in procedures and dispatch processes offer potential solutions. The increased use of hand-held computers or personal digital assistant (PDAs) to gather and provide information and the almost universal use of CAD will aid providers in performing the research necessary to change response time performance requirements, improving EMS system efficiency. Use of this technology will also likely improve patient care and reimbursement through more timely and accurate reporting and analysis. The medical director's role will be critical to ensuring potential changes don't compromise patient care. Obtaining a better understanding of how much time can safely elapse between the time of the 9-1-1 call and when patient-care activities

  7. Gain Flattening Filter Canceling Temperature Dependence of EDFA's gain

    Institute of Scientific and Technical Information of China (English)

    M. Ohmura; Y. Ishizawa; H. Nakaji; K. Hashimoto; T. Shibata; M. Shigehara; A. Inoue

    2003-01-01

    We have developed a gain flattening filter(GFF) for an erbium doped fiber (EDF) without temperature control systems. This GFF, which consists of temperature-sensitive long period gratings (LPGs)and a temperature compensated slanted fiber Bragg grating (SFBG), follows the gain shift of EDF with temperature. Gain variation of the EDFA less than 0.25dBp-p was achieved with the bandwidth of 37nm,and the temperature range 0-65℃ without and temperature control systems.

  8. Paul Scherrer Institut annual report 1995. Annex IIIA: Solid state research at large facilities

    Energy Technology Data Exchange (ETDEWEB)

    Baltensperger, U.; Lorenzen, R. [eds.

    1996-10-01

    The PSI research department IIIA is engaged in the final push to establish two research facilities: - the spallation neutron source (SINQ) and its instrumentation, - a positron source with high beam quality. The latter is essentially completed and ready for commissioning. The laboratory for Ion Beam Physics again served to many institutions with their accelerator mass spectroscopy by analyzing about 4000 samples. The new gas-jet facility and the neutron activation system at SINQ will be most important for the work of the laboratory of Radio- and Environmental Chemistry. Hence considerable effort has been put into the conception of this insertion device at the spallation source. Like in the previous year the laboratory of Neutron scattering was still relying on the access to neutron sources elsewhere than PSI. Regular access was available at ILL at a powder diffractometer and a triple axis spectrometer, upgraded and operated by PSI. Hence, besides the work for the instrumentation of SINQ, we had the opportunity to keep the scientific activities alive. Results of the laboratory of Astrophysics: one of the Radiation Environmental Monitors (REM) has now been in orbit for more than one year aboard the UK-satellite STRV-1B. The other monitor on a low circular orbit of a MIR-station also reports its results since about one year. (author) figs., tabs., refs.

  9. Large ameloblastic fibro-odontoma in a 3 year- old child: case report

    Directory of Open Access Journals (Sweden)

    Laurindo Moacir Sassi

    2011-01-01

    Full Text Available Introduction: The ameloblastic fibro-odontoma is a rare mixed neoplasm composed of proliferating odontogenic epithelium, ectomesenchymal tissue, and varying degrees of dental hard tissue formation. The mean age of the incidence is from 8-12 years and there is no gender or anatomic site predilection, but it is most commonly found in children’s or teenager’s jaws. Case report: A 3-year-old female patient showed a swelling in anterior maxilla, with facial asymmetry. Radiographically, it presented as a mixed lesion with undefined limits. Clinical hypothesis was odontoma. Enucleating surgery was conducted with tooth germs preservation. The final diagnosis was ameloblastic fibro-odontoma. No recurrence was observed at 1-year follow-up period, and the permanent tooth germs were correctly positioned for eruption. Conclusion: Although ameloblastic fibro-odontoma is a benign lesion, it developed in a very early age, with rapid growth and destruction of cortical bone. Proper surgical enucleation allowed the teeth maintenance.

  10. Recurrent renal cell carcinoma manifesting as a large intrathoracic fibrotic mass: A case report

    Science.gov (United States)

    KIM, JI HYUN; JEONG, JAE HOON; PARK, SUNG-HYUN; JEONG, JIN SEON; RYU, YOUNG-JOON; SONG, SEO-YOUNG

    2016-01-01

    Renal cell carcinomas (RCCs) have a strong tendency to metastasize, and the most common sites are the lungs, bones and liver. Late recurrence is another feature of the RCC, with lesions appearing ≥10 years after surgical treatment. However, fibrosis has rarely been associated with the disease. The present study reports a case of recurrent RCC that manifested as a fibrotic mass within the thorax. A 48-year-old man presented with dyspnea that had persisted for 3 days. The patient had undergone a right radical nephrectomy for stage II clear cell carcinoma of the kidney 6 years previously. The patient was a current smoker, with a smoking history of 20 pack-years. Chest radiography showed pleural effusion in the right thorax with an egg-sized mass shadow within the right upper lung (RUL) field. Computed tomography (CT) showed a main mass, 7 cm in diameter, within the RUL, with heterogeneous enhancement and multiple nodules of various sizes in the lungs, suggestive of primary lung cancer or metastatic RCC. A CT-guided percutaneous needle aspiration biopsy was obtained from the main mass, but histology revealed dense fibrous tissue without any malignant cells. Positron emission tomography-CT demonstrated an irregular hypermetabolic RUL mass, with a standardized uptake value (SUV) of 5.0, along the right pleura, and small pulmonary nodules (SUV, 2.0). Ultrasound-guided biopsy was attempted for a smaller hypermetabolic pleural nodule and the result was clear cell adenocarcinoma, consistent with the previous renal histology. The present study describes the case, along with a review of the relevant literature. PMID:27313703

  11. Self-reported disability in patients with inflammatory bowel disease largely determined by disease activity and illness perceptions.

    Science.gov (United States)

    van der Have, Mike; Fidder, Herma H; Leenders, Max; Kaptein, Ad A; van der Valk, Mirthe E; van Bodegraven, Ad A; Dijkstra, Gerard; de Jong, Dirk J; Pierik, Marieke; Ponsioen, Cyriel Y; van der Meulen-de Jong, Andrea E; van der Woude, C Janneke; van de Meeberg, Paul C; Romberg-Camps, Mariëlle J L; Clemens, Cees H M; Jansen, Jeroen M; Mahmmod, Nofel; Bolwerk, Clemens J M; Vermeijden, J Reinoud; Siersema, Peter D; Oldenburg, Bas

    2015-02-01

    The inflammatory bowel disease (IBD) disability index has recently been introduced to measure patients' physical, psychological, familial, and social limitations associated with IBD. We assessed factors related to self-reported disability and the relationship between disability and direct health care costs. A large cohort of patients with Crohn's disease (CD) and ulcerative colitis (UC) was prospectively followed for 2 years by 3 monthly web-based questionnaires. At 2 years, patients completed the IBD disability index, with lower score indicating more disability. Linear regression analysis was used to examine the impact of demographics, clinical characteristics, and illness perceptions on self-reported disability. Trends in direct health care costs across the disability severity groups minimal, mild, moderate, and severe, were tested. A total of 554 patients with CD and 424 patients with UC completed the IBD disability index (response rate, 45%). Both clinical characteristics and illness perceptions significantly contributed to self-reported disability (45%-47%, P = 0.000 and 8%-12%, P = 0.000, respectively). Patients with CD scored lower on the self-reported IBD disability index than patients with UC (0.255 versus 3.890, P disease activity, illness identity (higher number of symptoms attributed to IBD), and stronger emotional response. Disease duration and disease phenotype were not associated with self-reported disability. Direct health care costs increased with the worsening of self-reported disability (P = 0.000). More disability was reported by patients with CD than by UC. Self-reported disability in IBD was mainly determined by clinical disease activity and illness perceptions but not by disease duration or disease phenotype.

  12. Diffuse large B-cell lymphoma of the parotid gland: Cytological, histopathological, and immunohistochemical features: A rare case report

    Directory of Open Access Journals (Sweden)

    Sainath K Andola

    2016-01-01

    Full Text Available Primary malignant lymphomas of the salivary glands are rare, accounting for 2-5% of salivary gland tumors and 5% of extranodal lymphomas, frequently seen in the parotid gland. There are single case reports mentioned in the literature. Clinical presentation is not characteristic and the disease is often overlooked with delay in diagnosis and treatment. We are reporting a case of bilateral parotid gland lymphoma in a 55-year-old male, presented with bilateral enlarged parotids. Magnetic resonance imaging (MRI showed bilateral enlarged parotid glands with multiple well-defined intraparotid lesions. Fine Needle Aspiration Cytology (FNAC of both showed mixed population of lymphoid cells with large monocytoid cells with scant cytoplasm, anisonucleosis with prominent nucleoli, and numerous mitoses suggestive of non-Hodgkin's lymphoma (NHL. Histopathology showed sheets of large lymphoma cells destructing the salivary acini and infiltrating the periparotid fat. Immunohistochemistry (IHC showed diffuse CD20 positivity, B-cell lymphoma 6 protein (Bcl-6 was focally positive and negative for cluster of differentiation (CD 3, CD5, CD10, and Multiple myeloma oncogene-1 (MUM1 which led to the diagnosis of NHL-Diffuse large B cell type.

  13. Intracapsular and para-articular chondroma adjacent to large joints: report of three cases and review of the literature

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez-Lois, C.; Garcia-de-la-Torre, J.P.; SantosBriz-Terron, A.; Martinez-Tello, F.J. [Dept. of Pathology, University Hospital ' ' Doce de Octubre' ' , Madrid (Spain); Vila, J. [Dept. of Orthopedics and Traumatology, University Hospital ' ' Doce de Octubre' ' , Madrid (Spain); Manrique-Chico, J. [Dept. of Radiology, University Hospital ' ' Doce de Octubre' ' , Madrid (Spain)

    2001-12-01

    Para-articular chondroma is a rare tumor that has been reported in only 30 cases adjacent to large joints in the Anglo-Saxon literature. We report three new cases of this entity, describe its clinical, radiological and pathological features, and review the previous literature. Para-articular chondromas have an insidious clinical presentation and on radiographs show a large soft tissue mass with variable ossification. They appear as a lobulated mass of hyaline cartilage with variable endochondral ossification in the central area. These rare benign tumors arise from the capsule or the para-articular connective tissue of a large joint (mainly the knee), which suffers cartilaginous metaplasia and subsequent ossification. Cases 1 and 2 of this presentation fit all the features described previously. Case 3 has identical clinical features but differs from the former two cases in its microscopic appearance, being composed almost entirely of fibrocartilage and myxoid areas within the fibroadipose tissue of the joint instead of mature trabecular bone surrounded by hyaline cartilage. To the best of our knowledge this is the first description of this histological variant of para-articular chondroma. (orig.)

  14. Leiomiossarcoma do intestino grosso: relato de um caso Large bowel leiomyosarcoma: a case report

    Directory of Open Access Journals (Sweden)

    Simone Gonçalves Lopes

    2001-04-01

    Full Text Available Os autores relatam um caso de leiomiossarcoma de cólon ascendente acometendo um paciente do sexo masculino, de 49 anos de idade. O paciente iniciou o quadro com anemia e massa abdominal, e a evolução dos sintomas até o diagnóstico final foi de nove meses. Na radiografia simples do abdome havia presença de coleção aérea localizada no hipocôndrio direito, fora da topografia de alças; no clister opaco com duplo contraste foi demonstrado deslocamento inferior da flexura hepática e divertículos. A ultra-sonografia abdominal mostrou lesão expansiva heterogênea, com gás no seu interior, de localização sub-hepática. A tomografia computadorizada do abdome revelou massa escavada com nível líquido, sub-hepática, que não se impregnou pelo meio de contraste. Foi realizada hemicolectomia direita com ileocoloanastomose, e o diagnóstico histopatológico foi de leiomiossarcoma de cólon ascendente.The authors report a case of a 49-year-old male patient with leiomyosarcoma of the ascending colon. The patient presented with anemia and an abdominal mass, and the symptoms progressed until a final diagnosis was made nine months later. A plain abdominal x-ray showed the presence of gas outside the bowel, in the right hypochondrium. The double contrast barium enema showed a sublevel displacement of the hepatic flexure and diverticula. An abdominal ultrasound revealed a heterogeneous expansive lesion below the liver containing gas, and a computed tomography of the abdomen revealed an excavated mass below the liver containing liquid, that was not filled in by contrast medium. The patient was submitted to a right hemicolectomy with ileocoloanastomosis and the histopathological analysis of the excised material revealed a leiomyosarcoma of the ascending colon.

  15. An Unusual Presentation of B-Cell Lymphoma as a Large Isolated Epiglottic Mass: Case Report and Literature Review

    Directory of Open Access Journals (Sweden)

    Changxing Liu

    2016-01-01

    Full Text Available Extranodal presentation of B-cell lymphoma is uncommon. Isolated primary epiglottic B-cell lymphoma is even rarer. To our knowledge, there has been only one description of isolated B-cell lymphoma presenting as a large epiglottic mass. We report an unusual type of B-cell lymphoma of the epiglottis, as it could not be subtyped based on routine staining and hybridization. The lymphoma presented as a large isolated globular mass pedicled to the epiglottis, occupying most of the oropharynx, but did not have any ball-valving effect or increased respiratory efforts. Initial radiographic findings were nonspecific. The diagnosis of B-cell lymphoma was determined by transoral incisional biopsy under local anesthesia. The condition was treated successfully with chemoradiation. The current standard of treatment for high grade B-cell lymphoma is concurrent chemoradiotherapy, with excellent prognosis. Although rare, B-cell lymphoma should be considered when investigating pedunculated hypopharyngeal masses.

  16. An Unusual Case of a Large Hematorrachis Associated with Multi-Level Osteoporotic Vertebral Compression Fractures; a Case Report

    Directory of Open Access Journals (Sweden)

    T.V. Ravi Kumar

    2015-04-01

    Full Text Available Spinal epidural haemorrhage may present as back pain associated with radicular symptoms and can be a catastrophic clinical scenario with progression to paraplegia or even sudden death. Being a rare entity, it needs a high index ofclinical suspicion to diagnose it. Fractures have been documented as a cause of hematorrachis but such hematomas only extend to one or two vertebral segments. Large epidural hematomas are usually associated with conditions like bleeding diathesis, arterio-venous malformations, plasma cell myeloma, and non-Hodgkin’s lymphoma. Surgical management with immediate evacuation of the hematoma is the usual line of management in patients with neurological deficits. Though rare, monitored and careful conservative management can lead to recovery of neurological symptoms and resolution of the hematoma. We report a case of a very large post traumatic epidural hematorrchis extending to 11 vertebral segments from D3 to L1 vertebral bodies, who had a gradual spontaneous recovery.

  17. Spitting for Science: Danish High School Students Commit to a Large-Scale Self-Reported Genetic Study

    Science.gov (United States)

    Athanasiadis, Georgios; Jørgensen, Frank G.; Cheng, Jade Y.; Kjærgaard, Peter C.; Schierup, Mikkel H.; Mailund, Thomas

    2016-01-01

    Scientific outreach delivers science to the people. But it can also deliver people to the science. In this work, we report our experience from a large-scale public engagement project promoting genomic literacy among Danish high school students with the additional benefit of collecting data for studying the genetic makeup of the Danish population. Not only did we confirm that students have a great interest in their genetic past, but we were also gratified to see that, with the right motivation, adolescents can provide high-quality data for genetic studies. PMID:27571202

  18. Primary cutaneous large B-cell lymphoma, leg type: Report of two cases and review of literature

    Directory of Open Access Journals (Sweden)

    Santosh Kumar Mondal

    2012-01-01

    Full Text Available Primary cutaneous large B-cell lymphoma, leg type (PCLBCL-LT, is very rare neoplasm presenting on and confined to leg(s. PCLBCL-LT is distinguished from other type of primary cutaneous B-cell lymphoma (PCBCL by its frequent relapses and poorer prognosis. We report, two cases of PCLBCL-LT, occurring in two younger patients compared to published cases in literature. Both the patients were treated with chemotherapy and local radiotherapy. During the 1-year follow-up period one patient presented with extracutaneous dissemination and succumbed. The other patient is symptom free and follow-up period was uneventful.

  19. Surgical management of a large cleft palate in a Pierre Robin sequence: A case report and review of literature.

    Science.gov (United States)

    Andrews, Sherry; Sam, Mathew; Krishnan, Ramesh; Ramesh, Maya; Kunjappan, Shiji M

    2015-08-01

    Pierre Robin syndrome or Pierre Robin sequence (PRS) is a congenital etiologically heterogeneous condition presenting with various malformations. Here we are reporting the surgical management of an 18-month-old female baby who was referred from Department of Pediatrics with a complaint of a large cleft palate. She was taken up for palatoplasty with consent for elective tracheostomy. After genetic evaluation, the authors conclude that the presented case was a PRS in isolation with mild cardiac anomalies and an inferiorly placed hypoplastic epiglottis. Patient should be followed up and growth modifications of the jaws should be done.

  20. Large Shareholders' Position, Features of Property Right and the Gain of Control Benefits: Analysis from the Angle of Block Share Transfer%大股东地位、产权属性与控制权利益获取——基于大宗股权交易视角的分析

    Institute of Scientific and Technical Information of China (English)

    叶会; 李善民

    2011-01-01

    文章利用2006—2010年发生的大宗股权交易事件,对大股东获取控制权利益行为进行分析。研究结论表明,大股东在所有权结构中的控制能力越强,能够获取的控制权利益水平就越高,但是与非控股大股东相比,处于控股地位的大股东更倾向于以私有收益的方式实现控制权利益;与非国有股东相比,国有性质的股东更倾向于以私有收益的方式实现控制权利益;较好的市场环境能够有效抑制获取控制权私利行为,尤其是对控股大股东和国有性质股东获取私利行为的作用程度和效果更明显。%This paper explores the behavior of large shareholders' gai- ning control benefits by using the data of block share transfer from 2006 to 2010. The results show that under the stronger control of large shareholders in ownership structure, large shareholders will gain control benefits with a higher level, and compared to non-controlling shareholders, large sharehold- ers as controlling shareholders are more apt to achieve control benefits by private benefits; compared to non-state-owned shareholders, state-owned shareholders are more apt to achieve control benefits by private benefits; a sound market environment could effectively curb the behavior of gaining pri- vate benefits, especially the behavior of controlling and state-owned share- holders' gaining private benefits.

  1. Case Report of Diffuse Large B Cell Lymphoma of Uterine Cervix Treated at a Semiurban Cancer Centre in North India

    Directory of Open Access Journals (Sweden)

    Vibhor Sharma

    2016-01-01

    Full Text Available Lymphoma of the uterine cervix is very rare. We report a case of diffuse large B cell lymphoma (DLBCL involving the uterine cervix treated at a newly commissioned semiurban cancer centre in north India in 2015. Data for this study was obtained from the hospital electronic medical records and the patient’s case file. We also reviewed published case reports of uterine and cervical lymphoma involving forty-one patients. We treated a case of stage IV DLBCL cervix with six cycles of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone and intrathecal methotrexate followed by consolidation with radiotherapy. The patient showed complete response to chemotherapy. We conclude that, in advanced stage lymphoma involving uterus and cervix, combination of chemotherapy and radiotherapy is effective in short term.

  2. Locally advanced breast implant associated anaplastic large cell lymphoma: A case report of successful treatment with radiation and chemotherapy

    Directory of Open Access Journals (Sweden)

    Christopher Fleighton Estes

    2015-02-01

    Full Text Available The development of breast implant associated anaplastic large cell lymphoma (ALCL is a rare phenomenon. A typical presentation is an effusion associated with a breast implant. Less commonly, disease can become more advanced locoregionally or distantly. The optimal treatment schema is a topic of debate: localized ALCL can potentially be cured with implant removal alone, while other cases in the literature, including those that are more advanced, have been treated with varying combinations of surgery, chemotherapy, and external beam radiotherapy. This is a case report of breast implant ALCL with pathologically proven lymph node involvement, the fifth such patient reported. Our patient experienced a favorable outcome with radiation therapy and chemotherapy.

  3. Case Report of Diffuse Large B Cell Lymphoma of Uterine Cervix Treated at a Semiurban Cancer Centre in North India

    Science.gov (United States)

    Sridhar, Epari

    2016-01-01

    Lymphoma of the uterine cervix is very rare. We report a case of diffuse large B cell lymphoma (DLBCL) involving the uterine cervix treated at a newly commissioned semiurban cancer centre in north India in 2015. Data for this study was obtained from the hospital electronic medical records and the patient's case file. We also reviewed published case reports of uterine and cervical lymphoma involving forty-one patients. We treated a case of stage IV DLBCL cervix with six cycles of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone) and intrathecal methotrexate followed by consolidation with radiotherapy. The patient showed complete response to chemotherapy. We conclude that, in advanced stage lymphoma involving uterus and cervix, combination of chemotherapy and radiotherapy is effective in short term. PMID:27597906

  4. Liver and brain abscess caused by Aggregatibacter paraphrophilus in association with a large patent foramen ovale: a case report

    Directory of Open Access Journals (Sweden)

    Carmichael Andrew

    2010-02-01

    Full Text Available Abstract Introduction Aggregatibacter paraphrophilus (former name Haemophilus paraphrophilus is a normal commensal of the oral flora. It is a rare cause of hepatobiliary or intracerebral abscesses. Case presentation We report a case of a 53-year-old Caucasian man with a liver abscess and subsequent brain abscesses caused by Aggregatibacter paraphrophilus. The probable source of the infection was the oral flora of our patient following ingestion of a dental filling. The presence of a large patent foramen ovale was a predisposing factor for multifocal abscesses. Conclusion In this case report, we describe an unusual case of a patient with both liver and brain abscesses caused by an oral commensal Aggregatibacter paraphrophilus that can occasionally show significant pathogenic potential.

  5. Health problems awareness during travel among faculty members of a large university in Latin America: preliminary report

    Directory of Open Access Journals (Sweden)

    Ana Cristina Nakamura Tome

    2013-02-01

    Full Text Available Health safety during trips is based on previous counseling, vaccination and prevention of infections, previous diseases or specific problems related to the destination. Our aim was to assess two aspects, incidence of health problems related to travel and the traveler's awareness of health safety. To this end we phone-interviewed faculty members of a large public University, randomly selected from humanities, engineering and health schools. Out of 520 attempts, we were able to contact 67 (12.9% and 46 (68.6% agreed to participate in the study. There was a large male proportion (37/44, 84.1%, mature adults mostly in their forties and fifties (32/44, 72.7%, all of them with higher education, as you would expect of faculty members. Most described themselves as being sedentary or as taking occasional exercise, with only 15.9% (7/44 taking regular exercise. Preexisting diseases were reported by 15 travelers. Most trips lasted usually one week or less. Duration of the travel was related to the destination, with (12h or longer trips being taken by 68.2% (30/44 of travelers, and the others taking shorter (3h domestic trips. Most travelling was made by air (41/44 and only 31.8% (14/44 of the trips were motivated by leisure. Field research trips were not reported. Specific health counseling previous to travel was reported only by two (4.5%. Twenty seven of them (61.4% reported updated immunization, but 11/30 reported unchecked immunizations. 30% (9/30 reported travel without any health insurance coverage. As a whole group, 6 (13.6% travelers reported at least one health problem attributed to the trip. All of them were males travelling abroad. Five presented respiratory infections, such as influenza and common cold, one neurological, one orthopedic, one social and one hypertension. There were no gender differences regarding age groups, destination, type of transport, previous health counseling, leisure travel motivation or pre-existing diseases

  6. Health problems awareness during travel among faculty members of a large university in Latin America: preliminary report.

    Science.gov (United States)

    Tome, Ana Cristina Nakamura; Canello, Thaís Brandi; Luna, Expedito José de Albuquerque; Andrade Junior, Heitor Franco de

    2013-01-01

    Health safety during trips is based on previous counseling, vaccination and prevention of infections, previous diseases or specific problems related to the destination. Our aim was to assess two aspects, incidence of health problems related to travel and the traveler's awareness of health safety. To this end we phone-interviewed faculty members of a large public University, randomly selected from humanities, engineering and health schools. Out of 520 attempts, we were able to contact 67 (12.9%) and 46 (68.6%) agreed to participate in the study. There was a large male proportion (37/44, 84.1%), mature adults mostly in their forties and fifties (32/44, 72.7%), all of them with higher education, as you would expect of faculty members. Most described themselves as being sedentary or as taking occasional exercise, with only 15.9% (7/44) taking regular exercise. Preexisting diseases were reported by 15 travelers. Most trips lasted usually one week or less. Duration of the travel was related to the destination, with (12h) or longer trips being taken by 68.2% (30/44) of travelers, and the others taking shorter (3h) domestic trips. Most travelling was made by air (41/44) and only 31.8% (14/44) of the trips were motivated by leisure. Field research trips were not reported. Specific health counseling previous to travel was reported only by two (4.5%). Twenty seven of them (61.4%) reported updated immunization, but 11/30 reported unchecked immunizations. 30% (9/30) reported travel without any health insurance coverage. As a whole group, 6 (13.6%) travelers reported at least one health problem attributed to the trip. All of them were males travelling abroad. Five presented respiratory infections, such as influenza and common cold, one neurological, one orthopedic, one social and one hypertension. There were no gender differences regarding age groups, destination, type of transport, previous health counseling, leisure travel motivation or pre-existing diseases. Interestingly

  7. Diversity Gain through Antenna Blocking

    Directory of Open Access Journals (Sweden)

    V. Dehghanian

    2012-01-01

    Full Text Available As part of the typical usage mode, interaction between a handheld receiver antenna and the operator's RF absorbing body and nearby objects is known to generate variability in antenna radiation characteristics through blocking and pattern changes. It is counterintuitive that random variations in blocking can result in diversity gain of practical applicability. This diversity gain is quantified from a theoretical and experimental perspective. Measurements carried out at 1947.5 MHz verify the theoretical predictions, and a diversity gain of 3.1 dB was measured through antenna blocking and based on the utilized measurement setup. The diversity gain can be exploited to enhance signal detectability of handheld receivers based on a single antenna in indoor multipath environments.

  8. Advanced automated gain adjustments for in-vivo ultrasound imaging

    DEFF Research Database (Denmark)

    Moshavegh, Ramin; Hemmsen, Martin Christian; Martins, Bo

    2015-01-01

    Automatic gain adjustments are necessary on the state-of-the-art ultrasound scanners to obtain optimal scan quality, while reducing the unnecessary user interactions with the scanner. However, when large anechoic regions exist in the scan plane, the sudden and drastic variation of attenuations...... in the scanned media complicates the gain compensation. This paper presents an advanced and automated gain adjustment method that precisely compensate for the gains on scans and dynamically adapts to the drastic attenuation variations between different media. The proposed algorithm makes use of several...

  9. Giant Cell Tumor of Rib Arising Anteriorly as a Large Inframammary Mass: A Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Amit Sharma

    2012-01-01

    posteriorly. The rarity of this tumor poses diagnostic and therapeutic problems for physicians, especially when it is located in the anterior arc of the rib in close proximity to the breasts in female patients. Case Presentation. We report the case of a 32-year-old Asian female with a giant cell tumor of her anterior rib, presenting as a large inframammary mass. Computed tomography showed a tumor arising from the 7th rib anteriorly with marginal sclerosis, cortical destruction, and a soft tissue mass. She was treated with surgical resection, and the defect was reconstructed primarily. The surgical specimen measured 28.0 × 24.0 cm. The microscopic examination showed a large number of multinucleate giant cells scattered over the parenchyma. Patient recovered uneventfully and continues to be recurrence-free six years after surgical resection. Conclusion. We report the largest known case of giant cell tumor arising from the anterior aspect of a rib. We recommend including giant cell tumor in the differential diagnosis of chest wall masses especially in female patients, regardless of the size on clinical examination.

  10. High gain semiconductor optical amplifier — Laser diode at visible wavelength

    KAUST Repository

    Shen, Chao

    2017-02-07

    We reported on the first experimental demonstration of a two-section semipolar InGaN-based laser diode with monolithically integrated semiconductor optical amplifier (SOA-LD). The onset of amplification effect was measured at 4V SOA bias (VSOA). The SOA-LD shows a large gain of 5.32 dB at Vsoa = 6 V.

  11. Unity gain and non-unity gain quantum teleportation

    CERN Document Server

    Bowen, W P; Buchler, B C; Schnabel, R; Ralph, T C; Symul, T; Lam, P K

    2003-01-01

    We investigate continuous variable quantum teleportation. We discuss the methods presently used to characterize teleportation in this regime, and propose an extension of the measures proposed by Grangier and Grosshans \\cite{Grangier00}, and Ralph and Lam \\cite{Ralph98}. This new measure, the gain normalized conditional variance product $\\mathcal{M}$, turns out to be highly significant for continuous variable entanglement swapping procedures, which we examine using a necessary and sufficient criterion for entanglement. We elaborate on our recent experimental continuous variable quantum teleportation results \\cite{Bowen03}, demonstrating success over a wide range of teleportation gains. We analyze our results using fidelity; signal transfer, and the conditional variance product; and a measure derived in this paper, the gain normalized conditional variance product.

  12. A Unified Approach to High-Gain Adaptive Controllers

    Directory of Open Access Journals (Sweden)

    Ian A. Gravagne

    2009-01-01

    Full Text Available It has been known for some time that proportional output feedback will stabilize MIMO, minimum-phase, linear time-invariant systems if the feedback gain is sufficiently large. High-gain adaptive controllers achieve stability by automatically driving up the feedback gain monotonically. More recently, it was demonstrated that sample-and-hold implementations of the high-gain adaptive controller also require adaptation of the sampling rate. In this paper, we use recent advances in the mathematical field of dynamic equations on time scales to unify and generalize the discrete and continuous versions of the high-gain adaptive controller. We prove the stability of high-gain adaptive controllers on a wide class of time scales.

  13. Body weight gain and deep brain stimulation.

    Science.gov (United States)

    Rieu, Isabelle; Derost, Philippe; Ulla, Miguel; Marques, Ana; Debilly, Bérangère; De Chazeron, Ingrid; Chéreau, Isabelle; Lemaire, Jean Jacques; Boirie, Yves; Llorca, Pierre Michel; Durif, Franck

    2011-11-15

    Deep brain stimulation (DBS) is a neurosurgical technique that has now been available for some 25 years. It is used in the treatment of various motor disorders, e.g. Parkinson's disease (PD), essential tremor and dystonia, and neuropsychiatric illnesses, e.g. obsessive-compulsive disorder and Tourette syndrome. The surgical targets of DBS include the thalamic ventralis intermedius nucleus (Vim), the globus pallidus internus (GPi) and more recently the subthalamic nucleus (STN), currently considered as the reference target in the treatment of PD. In the last ten years, most studies in PD patients have described a rapid and marked weight gain in the months following DBS of the STN. This weight gain sometimes induces obesity and can have metabolic repercussions. The physiopathological mechanisms responsible for the weight gain are multifactorial (changes in energy metabolism and eating behaviour, reduction of motor complications, etc.). This review reports current knowledge concerning weight changes in patients treated by DBS with different surgical targets. It also describes the mechanisms responsible for weight gain and the health outcome for the patients.

  14. Factors associated with self-reported number of teeth in a large national cohort of Thai adults

    Directory of Open Access Journals (Sweden)

    Yiengprugsawan Vasoontara

    2011-11-01

    Full Text Available Abstract Background Oral health in later life results from individual's lifelong accumulation of experiences at the personal, community and societal levels. There is little information relating the oral health outcomes to risk factors in Asian middle-income settings such as Thailand today. Methods Data derived from a cohort of 87,134 adults enrolled in Sukhothai Thammathirat Open University who completed self-administered questionnaires in 2005. Cohort members are aged between 15 and 87 years and resided throughout Thailand. This is a large study of self-reported number of teeth among Thai adults. Bivariate and multivariate logistic regressions were used to analyse factors associated with self-reported number of teeth. Results After adjusting for covariates, being female (OR = 1.28, older age (OR = 10.6, having low income (OR = 1.45, having lower education (OR = 1.33, and being a lifetime urban resident (OR = 1.37 were statistically associated (p Conclusions This study addresses the gap in knowledge on factors associated with self-reported number of teeth. The promotion of healthy childhoods and adult lifestyles are important public health interventions to increase tooth retention in middle and older age.

  15. Large repayments of premium subsidies may be owed to the IRS if family income changes are not promptly reported.

    Science.gov (United States)

    Jacobs, Ken; Graham-Squire, Dave; Gould, Elise; Roby, Dylan

    2013-09-01

    Subsidies for health insurance premiums under the Affordable Care Act are refundable tax credits. They can be taken when taxes are filed or in advance, as reductions in monthly premiums that must be reconciled at tax filing. Recipients who take subsidies in advance will receive tax refunds if their subsidies were too small but will have to make repayments if their subsidies were too high. We analyzed predicted repayments and refunds for people receiving subsidies, using California as a case study. We found that many families could owe large repayments to the Internal Revenue Service at their next tax filing. If income changes were reported and credits adjusted in a timely manner throughout the tax year, the number of filers owing repayments would be reduced by 7-41 percent and the median size of repayments reduced by as much as 61 percent (depending on the level of changes reported and the method used to adjust the subsidy amounts). We recommend that the health insurance exchanges mandated by the Affordable Care Act educate consumers about how the subsidies work and the need to promptly report income changes. We also recommend that they provide tools and assistance to determine the amount of subsidies that enrollees should take in advance.

  16. Feedback Loop Gains and Feedback Behavior (1996)

    DEFF Research Database (Denmark)

    Kampmann, Christian Erik

    2012-01-01

    Linking feedback loops and system behavior is part of the foundation of system dynamics, yet the lack of formal tools has so far prevented a systematic application of the concept, except for very simple systems. Having such tools at their disposal would be a great help to analysts in understanding...... large, complicated simulation models. The paper applies tools from graph theory formally linking individual feedback loop strengths to the system eigenvalues. The significance of a link or a loop gain and an eigenvalue can be expressed in the eigenvalue elasticity, i.e., the relative change...... of an eigenvalue resulting from a relative change in the gain. The elasticities of individual links and loops may be found through simple matrix operations on the linearized system. Even though the number of feedback loops can grow rapidly with system size, reaching astronomical proportions even for modest systems...

  17. DNA gains at 8q23.2

    DEFF Research Database (Denmark)

    da Silva Veiga, Luciana Caricati; Bérgamo, Nádia Aparecida; dos Reis, Patrícia Pintor

    2003-01-01

    Gains or amplifications involving chromosome arm 8q are one of the most recurrent chromosomal alterations in head and neck tumors. To characterize previously reported gains, we performed fluorescence in situ hybridization (FISH) using the sequences BAC RP1179E1 and 8-centromere PMJ 128 as probes....

  18. Gain-switched all-fiber laser with narrow bandwidth

    DEFF Research Database (Denmark)

    Larsen, Casper; Giesberts, M.; Nyga, S.;

    2013-01-01

    Gain-switching of a CW fiber laser is a simple and cost-effective approach to generate pulses using an all-fiber system. We report on the construction of a narrow bandwidth (below 0.1 nm) gain-switched fiber laser and optimize the pulse energy and pulse duration under this constraint. The extracted...

  19. Reported frequency of physical activity in a large epidemiological study: relationship to specific activities and repeatability over time

    Directory of Open Access Journals (Sweden)

    Reeves Gillian K

    2011-06-01

    Full Text Available Abstract Background How overall physical activity relates to specific activities and how reported activity changes over time may influence interpretation of observed associations between physical activity and health. We examine the relationships between various physical activities self-reported at different times in a large cohort study of middle-aged UK women. Methods At recruitment, Million Women Study participants completed a baseline questionnaire including questions on frequency of strenuous and of any physical activity. About 3 years later 589,896 women also completed a follow-up questionnaire reporting the hours they spent on a range of specific activities. Time spent on each activity was used to estimate the associated excess metabolic equivalent hours (MET-hours and this value was compared across categories of physical activity reported at recruitment. Additionally, 18,655 women completed the baseline questionnaire twice, at intervals of up to 4 years; repeatability over time was assessed using the weighted kappa coefficient (κweighted and absolute percentage agreement. Results The average number of hours per week women reported doing specific activities was 14.0 for housework, 4.5 for walking, 3.0 for gardening, 0.2 for cycling, and 1.4 for all strenuous activity. Time spent and the estimated excess MET-hours associated with each activity increased with increasing frequency of any or strenuous physical activity reported at baseline (tests for trend, P weighted = 0.71 for questionnaires administered less than 6 months apart, and 52% (κweighted = 0.51 for questionnaires more than 2 years apart. Corresponding values for any physical activity were 57% (κweighted = 0.67 and 47% (κweighted = 0.58. Conclusions In this cohort, responses to simple questions on the frequency of any physical activity and of strenuous activity asked at baseline were associated with hours spent on specific activities and the associated estimated excess MET

  20. Spectral hole burning effects initiated by uniform signal intensities in a gain-flattened EDFA

    Institute of Scientific and Technical Information of China (English)

    A. R. Sarmani; S-J Sheih; F. R. Mahamd Adikan; M. A. Mahdi

    2011-01-01

    @@ Spectral hole burning (SHB) effects in a gain-flattened erbium-doped fiber amplifier (EDFA) are demonstrated to be significant in the presence of large signal power around the 1530-1532-nm wavelength range. These are the first effects reported in a setup employing equivalent power level distribution of 40 channels ranging from 1530 to 1561 nm. To explain this, the introduction of a new local population variable into the laser equation is required to support the original inversion ratio that is determined by the pump lasers. In the analysis section, spectroscopic parameters and high signal powers are considered to be other contributing parameters to the change in the gain characteristics. An improvement to this theoretical basis is suggested by implementing mathematical modeling to validate similarities between the gain shape of simulation to that obtained in the experiment.%Spectral hole burning (SHB) effects in a gain-fiattened erbium-doped fiber amplifier (EDFA) are demonstrated to be significant in the presence of large signal power around the 1530-1532-nm wavelength range.These are the first effects reported in a setup employing equivalent power level distribution of 40 channels ranging from 1530 to 1561 nm. To explain this, the introduction of a new local population variable into the laser equation is required to support the original inversion ratio that is determined by the pump lasers.In the analysis section, spectroscopic parameters and high signal powers are considered to be other contributing parameters to the change in the gain characteristics. An improvement to this theoretical basis is suggested by implementing mathematical modeling to validate similarities between the gain shape of simulation to that obtained in the experiment.

  1. Welfare Gains from Financial Liberalization.

    Science.gov (United States)

    Townsend, Robert M; Ueda, Kenichi

    2010-08-01

    Financial liberalization has been a controversial issue, as empirical evidence for growth enhancing effects is mixed. Here, we find sizable welfare gains from liberalization (cost to repression), though the gain in economic growth is ambiguous. We take the view that financial liberalization is a government policy that alters the path of financial deepening, while financial deepening is endogenously chosen by agents given a policy and occurs in transition towards a distant steady state. This history-dependent view necessitates the use of simulation analysis based on a growth model. Our application is a specific episode: Thailand from 1976 to 1996.

  2. Squamous cell carcinoma (Marjolin's ulcer in an orocutaneous fistula of a large mandibular ameloblastoma: a case report

    Directory of Open Access Journals (Sweden)

    Nthumba Peter M

    2011-08-01

    Full Text Available Abstract Introduction Ameloblastomas are rare lesions constituting 1% of all jaw tumors. Oral squamous cell carcinomas are common lesions; these constitute about 90% of all oral cancers. Concurrent tumors consisting of ameloblastoma and squamous cell carcinoma are extremely rare. Case presentation This case report describes a 35-year-old African man who presented with a large mandibular tumor with an orocutaneous fistula that was found to be an ameloblastoma on histopathological examination, with concurrent squamous cell carcinoma histology within the fistula. This presentation was consistent with a Marjolin's ulcer within an ameloblastoma. Conclusion Ameloblastomas and Marjolin's ulcers require different management strategies. Careful histopathological examination of surgical specimens is key to patient outcome, as treatment of these patients depends on an accurate diagnosis.

  3. Reporting the first 3 years of 225-GHz opacity measurements at the site of the Large Millimeter Telescope Alfonso Serrano

    Science.gov (United States)

    Zeballos, M.; Ferrusca, D.; Contreras R., J.; Hughes, D. H.

    2016-07-01

    The Large Millimeter Telescope Alfonso Serrano (LMT) is located in Puebla, Mexico, at an altitude of 4580 m. It is currently the largest single-dish telescope constructed to observe the Universe at wavelengths between 0.85 and 4 mm. Identifying interstellar molecules, exploring dense dark clouds, and understanding the properties of cold matter and interstellar dust in the local and distant Universe are among its main scientific goals. Since June 2013, the LMT has conducted four shared-risk early science campaigns* observing at 1.1 mm (AzTEC), and 3 mm (RSR) with the aid of a new meteorological and radiometer system to guide the flexibility scheduling of observing time. Here we report measurements of the atmospheric opacity taken with this radiometer at 225 GHz between June 2013 and April 2016. These measurements show that the LMT site has exceptional weather conditions with opacities season, making it a very convenient site for sub-millimeter/millimeter astronomy.

  4. Application of concentrated growth factors in reconstruction of bone defects after removal of large jaw cysts: The two cases report

    Directory of Open Access Journals (Sweden)

    Mirković Siniša

    2015-01-01

    Full Text Available Introduction. Coagulation and blood clot formation in bone defects is sometimes followed by retraction of a blood clot and serum extrusion, thus producing peripheral serum-filled spaces between bony wall and coagulum. This can result in a higher incidence of postoperative complications. Stabilization of blood coagulum, which enables successful primary healing, may be accomplished by autotransplantation, allotransplantation, xenotransplantation, or application of autologous platelet concentrate and concentrated growth factors (CGF. Case report. Two patients with large cystic lesions in the upper and lower jaw were presented. In both patients postoperative bony defects were filled with autologous fibrin rich blocks containing CGF. Postoperative course passed uneventfully. Conclusion. Application of fibrin rich blocks containing CGF is one of the possible methods for reconstruction of bone defects. CGF can be applied alone or mixed with a bone graft. The method is relatively simple, without risk of transmissible and allergic diseases and economically feasible.

  5. Successful laparoscopic bipolar coagulation of a large arteriovenous malformation due to invasive trophoblastic disease: a case report.

    Science.gov (United States)

    Corusic, Ante; Barisic, Dubravko; Lovric, Helena; Despot, Albert; Planinic, Pavao

    2009-01-01

    We report the case of an acquired large arteriovenous malformation due to invasive gestational trophoblastic tumor that was treated successfully with laparoscopic surgery. After 4 cycles of methotrexate chemotherapy, a vascular tangle (volume, 28 cm(3)) was noted that emerged from the right uterine horn, invading the broad ligament adjacent to the uterine artery. Doppler ultrasonography along with magnetic resonance arteriography confirmed the diagnosis. The location, size and relation of this arteriovenous malformation to the uterine vasculature demanded urgent intervention. Laparoscopy was performed, and bipolar coagulation of the ovarian and uterine artery feeding branches was achieved after surgical resection of the tumor. The defect in the uterine wall with an intact uterine cavity was reconstructed using sutures. There were no intraoperative or postoperative complications. The patient underwent chemotherapy, and at 2-month follow-up was cured and has since had regular menstrual cycles.

  6. Primary diffuse large B-cell lymphoma of the prostate: A report of two cases with diagnostic considerations

    Directory of Open Access Journals (Sweden)

    Aanchal Kakkar

    2015-01-01

    Full Text Available Primary prostatic lymphomas are extremely unusual neoplasms. Their rarity and nonspecific symptomatology at presentation usually prompt a clinical diagnosis of benign prostatic hyperplasia or chronic prostatitis, leading to significant delay in diagnosis. Clinical examination, serum prostate-specific antigen levels, and transrectal ultrasonography (TRUS are not of much utility in differential diagnosis, and histological examination is the gold standard. We report two cases of primary non-Hodgkin lymphoma of prostate, diffuse large B-cell type, diagnosed on TRUS-guided prostatic biopsies. Correct diagnosis is of crucial importance as the therapeutic strategy for lymphoma is radically different from that for carcinoma, and early detection of prostatic lymphoma can be potentially curative. Thus, knowledge of this rare entity, inclusion in differential diagnosis of lower urinary tract obstruction, and application of an appropriate immunohistochemical panel are essential so as not to miss this unusual diagnosis and to avoid unnecessary surgery.

  7. Acute pseudo-obstruction of the large bowel with caecal perforation following normal vaginal delivery: a case report

    Directory of Open Access Journals (Sweden)

    Seenath Marlon

    2010-04-01

    Full Text Available Abstract Introduction Acute pseudo-obstruction of the large bowel following normal vaginal delivery is an extremely rare complication of normal vaginal delivery. It can be fatal if not recognized early. Only one previous report has been found in the English literature. Case presentation A 36-year old Caucasian, normally fit woman presented with abdominal distension and vomiting five days post-normal vaginal delivery at term. Localised peritonitis in the right iliac fossa developed in the next few days, and caecal perforation was found at laparotomy, without evidence of appendicitis or colitis. Conclusion Although very rare, Ogilvie's syndrome should be considered by obstetricians, general surgeons and general practitioners as a potential cause of vomiting and abdominal pain following normal vaginal delivery. Early recognition and management are essential to minimize the possibility of developing serious complications.

  8. Solar total energy-large scale experiment, Shenandoah, Georgia site. Annual report, June 1977--June 1978. [For Bleyle Knitwear Plant

    Energy Technology Data Exchange (ETDEWEB)

    None,

    1978-06-01

    The site was described in terms of location, suitably, accessibility, and other factors. Detailed descriptions of the Solar Total Energy-Large Scale Experiment Application (STE-LSE) (Bleyle of America, Inc., Knitwear Plant), the DOE owned Meteorology Station operating at the site, and the instrumentation provided by the Georgia Power Company to measure energy usage within the knitwear plant are included. A detailed report of progress is given at the Shenandoah Site, introduced by the STE-LSE schedule and the Cooperative Agreement work tasks. Progress is described in terms of the following major task areas: site/application; instrumentation/data acquisition; meteorology station; site to STES interface; information dissemination. A brief overview of milestones to be accomplished is given, followed by these appendices: solar easement agreement, interface drawing set, and additional site background data. (MHR)

  9. Gain properties of dye-doped polymer thin films

    CERN Document Server

    Gozhyk, I; Rabbani, H; Djellali, N; Forget, S; Chenais, S; Ulysse, C; Brosseau, A; Gauvin, S; Zyss, J; Lebental, M

    2014-01-01

    The demonstration of an electrically pumped organic laser remains a major issue of organic optoelectronics for several decades. Nowadays, hybrid pumping seems a promising compromise where the organic material is optically pumped by an electrically pumped inorganic device on chip. This technical solution requires therefore an optimization of the organic gain medium under optical pumping. Here, we report a detailed study of gain features of dye-doped polymer thin films, in particular we introduce the gain efficiency $K$, in order to facilitate comparison between material and experimental conditions. First, we measure the bulk gain by the means of a pump-probe setup, and then present in details several factors which modify the actual gain of the layer, namely the confinement factor, the pump polarization, the molecular anisotropy, and the re-absorption. The usual model to evaluate the gain leads to an overestimation by more than one order of magnitude, which stresses the importance to design the devices accordin...

  10. Heuristic Portfolio Trading Rules with Capital Gain Taxes

    DEFF Research Database (Denmark)

    Fischer, Marcel; Gallmeyer, Michael

    We study the out-of-sample performance of portfolio trading strategies when an investor faces capital gain taxation and proportional transaction costs. Under no capital gain taxation and no transaction costs, we show that, consistent with DeMiguel, Garlappi, and Uppal (2009), a simple 1/N trading...... strategy is not dominated out-of-sample by a variety of optimizing trading strategies, except the parametric portfolios of Brandt, Santa-Clara, and Valkanov (2009). With dividend and realization-based capital gain taxes, the welfare costs of the taxes are large with the cost being as large as 30% of wealth...... in some cases. Overlaying simple tax trading heuristics on these trading strategies improves out-of-sample performance. In particular, the 1/N trading strategy's welfare gains improve when a variety of tax trading heuristics are also imposed. For medium to large transaction costs, no trading strategy can...

  11. Matrix-induced autologous chondrocyte implantation for a large chondral defect in a professional football player: a case report

    Directory of Open Access Journals (Sweden)

    Beyzadeoglu Tahsin

    2012-06-01

    Full Text Available Abstract Introduction Matrix-assisted autologous chondrocyte implantation is a well-known procedure for the treatment of cartilage defects, which aims to establish a regenerative milieu and restore hyaline cartilage. However, much less is known about third-generation autologous chondrocyte implantation application in high-level athletes. We report on the two-year follow-up outcome after matrix-assisted autologous chondrocyte implantation to treat a large cartilage lesion of the lateral femoral condyle in a male Caucasian professional football player. Case presentation A 27-year-old male Caucasian professional football player was previously treated for cartilage problems of his left knee with two failed microfracture procedures resulting in a 9 cm2 Outerbridge Grade 4 chondral lesion at his lateral femoral condyle. Preoperative Tegner-Lysholm and Brittberg-Peterson scores were 64 and 58, and by the second year they were 91 and 6. An evaluation with magnetic resonance imaging demonstrated filling of the defect with the signal intensity of the repair tissue resembling healthy cartilage. Second-look arthroscopy revealed robust, smooth cartilage covering his lateral femoral condyle. He returned to his former competitive level without restrictions or complaints one year after the procedure. Conclusions This case illustrates that robust cartilage tissue can be obtained with a matrix-assisted autologous chondrocyte implantation procedure even after two failed microfracture procedures in a large (9 cm2 cartilage defect. To the best of our knowledge, this is the first case report on the application of the third-generation cell therapy treatment technique, matrix-assisted autologous chondrocyte implantation, in a professional football player.

  12. Development of low cost systems for co-utilisation of biomass in large power plant. Mid term review report

    Energy Technology Data Exchange (ETDEWEB)

    Livingston, W.R.

    2003-07-01

    Interest in the cofiring of biomass materials with coal in large coal-fired power stations in the UK has increased significantly in recent years in response to the potential additional income from Renewables Obligation Certificates (ROCs). It is anticipated that most coal-fired power stations in the UK will have the capability to cofire biomass materials by the end of 2003. This mid-term review report examines the various stages in the route to fully commercial operation of biomass cofiring at coal-fired power stations, the availability of suitable biomass materials in the UK and the technical options for cofiring. The factors affecting the economics of biomass cofiring in large coal-fired boilers are discussed including the delivered price of biofuels, the future value of ROCs, the development costs of cofiring projects, the 25% ceiling on cofiring imposed by the Renewables Obligation Order 2002 and the use of preblending. An overview of the current status of cofiring in the UK is presented, which includes a summary of the results of trials already carried out by operators of coal-fired power stations and a discussion of the future prospects for biomass cofiring in the UK.

  13. Determining productivity gains from herbaceous vegetation management with 'age-shift' calculations

    Science.gov (United States)

    David B. South; James H. Miller; Mark O. Kimberley; Curtis L. Vanderschaaf

    2006-01-01

    Gains in stand volume that result from competition control and fertilization are sometimes reported as 'percentage gains'. Because percentage gains arithmetically decline over time asstand volume increases, plantation managers have difficultyin using percentage gains to project growth and revenues. The 'age-shift' method quantifies the year...

  14. Sabbatical leave: who gains and how much?

    Science.gov (United States)

    Davidson, Oranit B; Eden, Dov; Westman, Mina; Cohen-Charash, Yochi; Hammer, Leslie B; Kluger, Avraham N; Krausz, Moshe; Maslach, Christina; O'Driscoll, Michael; Perrewé, Pamela L; Quick, James Campbell; Rosenblatt, Zehava; Spector, Paul E

    2010-09-01

    A rigorous quasi-experiment tested the ameliorative effects of a sabbatical leave, a special case of respite from routine work. We hypothesized that (a) respite increases resource level and well-being and (b) individual differences and respite features moderate respite effects. A sample of 129 faculty members on sabbatical and 129 matched controls completed measures of resource gain, resource loss, and well-being before, during, and after the sabbatical. Among the sabbatees, resource loss declined and resource gain and well-being rose during the sabbatical. The comparison group showed no change. Moderation analysis revealed that those who reported higher respite self-efficacy and greater control, were more detached, had a more positive sabbatical experience, and spent their sabbatical outside their home country enjoyed more enhanced well-being than others.

  15. A progress report for the large block test of the coupled thermal-mechanical-hydrological-chemical processes

    Energy Technology Data Exchange (ETDEWEB)

    Lin, W.; Wilder, D.G.; Blink, J. [and others

    1994-10-01

    This is a progress report on the Large Block Test (LBT) project. The purpose of the LBT is to study some of the coupled thermal-mechanical-hydrological-chemical (TMHC) processes in the near field of a nuclear waste repository under controlled boundary conditions. To do so, a large block of Topopah Spring tuff will be heated from within for about 4 to 6 months, then cooled down for about the same duration. Instruments to measure temperature, moisture content, stress, displacement, and chemical changes will be installed in three directions in the block. Meanwhile, laboratory tests will be conducted on small blocks to investigate individual thermal-mechanical, thermal-hydrological, and thermal-chemical processes. The fractures in the large block will be characterized from five exposed surfaces. The minerals on fracture surfaces will be studied before and after the test. The results from the LBT will be useful for testing and building confidence in models that will be used to predict TMHC processes in a repository. The boundary conditions to be controlled on the block include zero moisture flux and zero heat flux on the sides, constant temperature on the top, and constant stress on the outside surfaces of the block. To control these boundary conditions, a load-retaining frame is required. A 3 x 3 x 4.5 m block of Topopah Spring tuff has been isolated on the outcrop at Fran Ridge, Nevada Test Site. Pre-test model calculations indicate that a permeability of at least 10{sup -15} m{sup 2} is required so that a dryout zone can be created within a practical time frame when the block is heated from within. Neutron logging was conducted in some of the vertical holes to estimate the initial moisture content of the block. It was found that about 60 to 80% of the pore volume of the block is saturated with water. Cores from the vertical holes have been used to map the fractures and to determine the properties of the rock. A current schedule is included in the report.

  16. Peritonitis secondary to traumatic duodenal laceration in the presence of a large pancreatic pseudocyst: a case report

    Directory of Open Access Journals (Sweden)

    Seenath Marlon M

    2011-10-01

    Full Text Available Abstract Introduction A pancreatic pseudocyst is a common sequela of severe acute pancreatitis. Commonly, it presents with abdominal pain and a mass in the epigastrium several weeks after the acute episode and can be managed conservatively, endoscopically or surgically. We report a patient with a pancreatic pseudocyst awaiting endoscopic therapy who developed a life-threatening complication following a rather innocuous trauma to the abdomen. Case presentation A 23-year-old Asian male student presented as an emergency with an acute abdomen a week after a minor trauma to his upper abdomen. The injury occurred when he was innocently punched in the abdomen by a friend. He experienced only moderate discomfort briefly at the time. His past medical history included coeliac disease and an admission four months previously with severe acute pancreatitis. He was hospitalized for 15 days; his pancreatitis was thought to be due to alcohol binge drinking on weekends. Ultrasound scanning showed no evidence of gallstone disease. Five days after the trauma, he became anorexic, lethargic and feverish and started vomiting bilious content. Seven days post-trauma, he presented to our emergency department with severe abdominal pain. An emergency laparotomy was performed where a transverse linear duodenal laceration was found at the junction of the first and second part of his duodenum, with generalized peritonitis. His stomach and duodenum were stretched over a large pancreatic pseudocyst posterior to his stomach. It was postulated that an incomplete duodenal injury (possibly a serosal tear occurred following the initial minor trauma, which was followed by local tissue necrosis at the injury site resulting in a delayed presentation of generalized peritonitis. Conclusion This is the first reported case of a traumatic duodenal laceration following minor blunt trauma in the presence of a large pancreatic pseudocyst. Minor blunt abdominal trauma in a normal healthy adult

  17. Large-scale system effectiveness analysis. Sub-problem 3: a conceptual framework for system cost. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Myers, D.R.; Lee, W.C.; Yabroff, I.W.

    1980-06-16

    The effectiveness of a large-scale electric power system can be measured by four factors: system performance, system availability, system cost, and system worth (from the user perspective). In response to the need for synergistic effectiveness measures. A broad, multi-contractor research project is being conducted to integrate those four categories. This report describes system cost at two levels: a conceptual framework for measuring the total cost of producing electricity under diverse system effectiveness measures, and a set of general cost inputs that relate the framework to specific utility types. In this report, Chapter II describes the general-level conceptual framework for assessing the cost of system effectivenss attributes. Chapter III shows how the actual costs of a power system can be disaggregated and then integrated into the broad-level conceptual framework. Chapter IV utilizes the conceptual framework and the concepts underlying its development to produce some concrete examples of measures of cost of system effectiveness. Appendix A is a more in-depth look at the cost of fuel, and illustrates the level of analytical detail necessary for putting the framework into practice.

  18. Design and implementation of an open source indexing solution for a large set of radiological reports and images.

    Science.gov (United States)

    Voet, T; Devolder, P; Pynoo, B; Vercruysse, J; Duyck, P

    2007-11-01

    This paper hopes to share the insights we experienced during designing, building, and running an indexing solution for a large set of radiological reports and images in a production environment for more than 3 years. Several technical challenges were encountered and solved in the course of this project. One hundred four million words in 1.8 million radiological reports from 1989 to the present were indexed and became instantaneously searchable in a user-friendly fashion; the median query duration is only 31 ms. Currently, our highly tuned index holds 332,088 unique words in four languages. The indexing system is feature-rich and language-independent and allows for making complex queries. For research and training purposes it certainly is a valuable and convenient addition to our radiology informatics toolbox. Extended use of open-source technology dramatically reduced both implementation time and cost. All software we developed related to the indexing project has been made available to the open-source community covered by an unrestricted Berkeley Software Distribution-style license.

  19. Semiconductor radiation detector with internal gain

    Energy Technology Data Exchange (ETDEWEB)

    Iwanczyk, Jan (Los Angeles, CA); Patt, Bradley E. (Sherman Oaks, CA); Vilkelis, Gintas (Westlake Village, CA)

    2003-04-01

    An avalanche drift photodetector (ADP) incorporates extremely low capacitance of a silicon drift photodetector (SDP) and internal gain that mitigates the surface leakage current noise of an avalanche photodetector (APD). The ADP can be coupled with scintillators such as CsI(Tl), NaI(Tl), LSO or others to form large volume scintillation type gamma ray detectors for gamma ray spectroscopy, photon counting, gamma ray counting, etc. Arrays of the ADPs can be used to replace the photomultiplier tubes (PMTs) used in conjunction with scintillation crystals in conventional gamma cameras for nuclear medical imaging.

  20. Differences in the Reporting of Racial and Socioeconomic Disparities among Three Large National Databases for Breast Reconstruction.

    Science.gov (United States)

    Kamali, Parisa; Zettervall, Sara L; Wu, Winona; Ibrahim, Ahmed M S; Medin, Caroline; Rakhorst, Hinne A; Schermerhorn, Marc L; Lee, Bernard T; Lin, Samuel J

    2017-04-01

    Research derived from large-volume databases plays an increasing role in the development of clinical guidelines and health policy. In breast cancer research, the Surveillance, Epidemiology and End Results, National Surgical Quality Improvement Program, and Nationwide Inpatient Sample databases are widely used. This study aims to compare the trends in immediate breast reconstruction and identify the drawbacks and benefits of each database. Patients with invasive breast cancer and ductal carcinoma in situ were identified from each database (2005-2012). Trends of immediate breast reconstruction over time were evaluated. Patient demographics and comorbidities were compared. Subgroup analysis of immediate breast reconstruction use per race was conducted. Within the three databases, 1.2 million patients were studied. Immediate breast reconstruction in invasive breast cancer patients increased significantly over time in all databases. A similar significant upward trend was seen in ductal carcinoma in situ patients. Significant differences in immediate breast reconstruction rates were seen among races; and the disparity differed among the three databases. Rates of comorbidities were similar among the three databases. There has been a significant increase in immediate breast reconstruction; however, the extent of the reporting of overall immediate breast reconstruction rates and of racial disparities differs significantly among databases. The Nationwide Inpatient Sample and the National Surgical Quality Improvement Program report similar findings, with the Surveillance, Epidemiology and End Results database reporting results significantly lower in several categories. These findings suggest that use of the Surveillance, Epidemiology and End Results database may not be universally generalizable to the entire U.S.

  1. Sudden gains in two psychotherapies for posttraumatic stress disorder.

    Science.gov (United States)

    König, Julia; Karl, Regina; Rosner, Rita; Butollo, Willi

    2014-09-01

    We examined sudden, large, and stable shifts in symptoms from one therapy session to the next in two treatments for posttraumatic stress disorder (PTSD). Shifts in a positive direction (sudden gains) have so far been more frequently analyzed than those in a negative direction (sudden losses). We analyzed data from 102 outpatients suffering from PTSD who received either a cognitive-behavioral or a Gestalt-based intervention. Sudden gains, at 22.5%, were more frequent than sudden losses (3.9% of patients). Participants who had experienced sudden gains had lower PTSD scores at posttreatment, but not at the 6-month follow-up. As sudden losses were so rare, they were not analyzed statistically. Sudden gains accounted for 52% of overall treatment gains or 26% of overall change in a positive direction. Among very successful patients, those with sudden gains were overrepresented, but in absolute terms, there were as many patients without sudden gains in this group. There was no connection between sudden gains and type of intervention or depressive symptoms. Sudden gains and sudden losses occurred in our sample of PTSD patients, but in the light of current results, their clinical importance seems to be limited.

  2. Raman gains of ADP and KDP crystals

    Institute of Scientific and Technical Information of China (English)

    周海亮; 柴向旭; 张清华; 王波; 许心光; 王正平; 孙洵; 张芳; 张立松; 刘宝

    2015-01-01

    In this paper, the Raman gain coefficients of ammonium dihydrogen phosphate (ADP) and potassium dihydrogen phosphate (KDP) crystals are measured. By using a pump source of a 30-ps, 532-nm laser, the gain coefficients of ADP and KDP are 1.22 cm/GW, and 0.91 cm/GW, respectively. While for a 20-ps, 355-nm pump laser, the gain coefficients of these two crystals are similar, which are 1.95 cm/GW for ADP and 1.86 for KDP. The present results indicate that for ultra-violet frequency conversion, the problem of stimulated Raman scattering for ADP crystal will not be more serious than that for KDP crystal. Considering other advantages such the larger nonlinear optical coefficient, higher laser damage threshold, and lower noncritical phase-matching temperature, it can be anticipated that ADP will be a powerful competitor to KDP in large aperture, high energy third-harmonic generation or fourth-harmonic generation applications.

  3. LARGE-SCALE ENFORCEMENT OF THE FAIR CREDIT REPORTING ACT AND THE ROLE OF STATE ATTORNEYS GENERAL

    National Research Council Canada - National Science Library

    Austin H. Krist

    2015-01-01

    .... Government regulation of credit reporting is critical because the structure of the credit reporting industry does not adequately incentivize credit reporting agencies to maintain accuracy in consumers' credit reports...

  4. Mass Gains of the Antarctic Ice Sheet Exceed Losses

    Science.gov (United States)

    Zwally, H. Jay; Li, Jun; Robbins, John; Saba, Jack L.; Yi, Donghui; Brenner, Anita; Bromwich, David

    2012-01-01

    During 2003 to 2008, the mass gain of the Antarctic ice sheet from snow accumulation exceeded the mass loss from ice discharge by 49 Gt/yr (2.5% of input), as derived from ICESat laser measurements of elevation change. The net gain (86 Gt/yr) over the West Antarctic (WA) and East Antarctic ice sheets (WA and EA) is essentially unchanged from revised results for 1992 to 2001 from ERS radar altimetry. Imbalances in individual drainage systems (DS) are large (-68% to +103% of input), as are temporal changes (-39% to +44%). The recent 90 Gt/yr loss from three DS (Pine Island, Thwaites-Smith, and Marie-Bryd Coast) of WA exceeds the earlier 61 Gt/yr loss, consistent with reports of accelerating ice flow and dynamic thinning. Similarly, the recent 24 Gt/yr loss from three DS in the Antarctic Peninsula (AP) is consistent with glacier accelerations following breakup of the Larsen B and other ice shelves. In contrast, net increases in the five other DS of WA and AP and three of the 16 DS in East Antarctica (EA) exceed the increased losses. Alternate interpretations of the mass changes driven by accumulation variations are given using results from atmospheric-model re-analysis and a parameterization based on 5% change in accumulation per degree of observed surface temperature change. A slow increase in snowfall with climate waRMing, consistent with model predictions, may be offsetting increased dynamic losses.

  5. Discordant lymphoma consisting of mediastinal large B-cell lymphoma and nodular sclerosis Hodgkin lymphoma in the right supraclavicular lymph nodes: a case report

    National Research Council Canada - National Science Library

    Zhang, Chun; Yi, Yuanxue; Chen, Chunyan; Wang, Jianrong; Liu, Zhu

    2015-01-01

    .... Here, we report a case of discordant lymphoma in a 34-year-old female patient that involved mediastinal large B-cell lymphoma and nodular sclerosis Hodgkin lymphoma in the right supraclavicular lymph nodes...

  6. On controllability of neuronal networks with constraints on the average of control gains.

    Science.gov (United States)

    Tang, Yang; Wang, Zidong; Gao, Huijun; Qiao, Hong; Kurths, Jürgen

    2014-12-01

    Control gains play an important role in the control of a natural or a technical system since they reflect how much resource is required to optimize a certain control objective. This paper is concerned with the controllability of neuronal networks with constraints on the average value of the control gains injected in driver nodes, which are in accordance with engineering and biological backgrounds. In order to deal with the constraints on control gains, the controllability problem is transformed into a constrained optimization problem (COP). The introduction of the constraints on the control gains unavoidably leads to substantial difficulty in finding feasible as well as refining solutions. As such, a modified dynamic hybrid framework (MDyHF) is developed to solve this COP, based on an adaptive differential evolution and the concept of Pareto dominance. By comparing with statistical methods and several recently reported constrained optimization evolutionary algorithms (COEAs), we show that our proposed MDyHF is competitive and promising in studying the controllability of neuronal networks. Based on the MDyHF, we proceed to show the controlling regions under different levels of constraints. It is revealed that we should allocate the control gains economically when strong constraints are considered. In addition, it is found that as the constraints become more restrictive, the driver nodes are more likely to be selected from the nodes with a large degree. The results and methods presented in this paper will provide useful insights into developing new techniques to control a realistic complex network efficiently.

  7. Energy performance of windows based on the net energy gain

    DEFF Research Database (Denmark)

    Svendsen, Svend; Kragh, Jesper; Laustsen, Jacob Birck

    2005-01-01

    The paper presents a new method to set up energy performance requirements and energy classes for windows of all dimensions and configurations. The net energy gain of windows is the solar gain minus the heat loss integrated over the heating season. The net energy gain can be calculated for one...... orientation or averaged over different orientations. The averaged value may be used for energy labeling of windows of standard size. Requirements in building codes may also be based on the net energy gain instead of the thermal transmittance of the window. The size and the configuration of the window, i.......e. number of glazing units, have a very large effect on the net energy gain. Therefore the energy labeling or the requirements based on the standard size may not give valid information on the energy performance of windows of non-standard size. The paper presents a method to set up requirements and classes...

  8. SiPM Gain Stabilization Studies for Adaptive Power Supply

    CERN Document Server

    AUTHOR|(CDS)2074257; Zalieckas, Justas; Cvach, Jaroslav; Kvasnicka, Jiri; Polak, Ivo

    2016-01-01

    We present herein gain stabilization studies of SiPMs using a climate chamber at CERN. We present results for four detectors not tested before, three from Hamamatsu and one from KETEK. Two of the Hamamatsu SiPMs are novel sensors with trenches that reduce cross talk. We use an improved readout system with a digital oscilloscope controlled with a dedicated LabView program. We improved and automized the analysis to deal with large datasets. We have measured the gain-versus-bias-voltage dependence at fixed temperature and gain-versus-temperature dependence at fixed bias voltage to determine the bias voltage dependence on temperature $V(T)$ for stable gain. We show that the gain remains stable to better than $\\pm 0.5\\%$ in the $20^\\circ \\rm C - 30^\\circ C$ temperature range if the bias voltage is properly adjusted with temperature.

  9. Large-scale data reporting of paediatric morbidity and mortality in developing countries: it can be done

    Science.gov (United States)

    Duke, Trevor; Yano, Edilson; Hutchinson, Adrian; Hwaihwanje, Ilomo; Aipit, Jimmy; Tovilu, Mathias; Uluk, Tarcisius; Rongap, Theresia; Vetuna, Beryl; Lagani, William; Amini, James

    2016-01-01

    Although the WHO recommends all countries use International Classification of Diseases (ICD)-10 coding for reporting health data, accurate health facility data are rarely available in developing or low and middle income countries. Compliance with ICD-10 is extremely resource intensive, and the lack of real data seriously undermines evidence-based approaches to improving quality of care and to clinical and public health programme management. We developed a simple tool for the collection of accurate admission and outcome data and implemented it in 16 provincial hospitals in Papua New Guinea over 6 years. The programme was low cost and easy to use by ward clerks and nurses. Over 6 years, it gathered data on the causes of 96 998 admissions of children and 7128 deaths. National reports on child morbidity and mortality were produced each year summarising the incidence and mortality rates for 21 common conditions of children and newborns, and the lessons learned for policy and practice. These data informed the National Policy and Plan for Child Health, triggered the implementation of a process of clinical quality improvement and other interventions to reduce mortality in the neediest areas, focusing on diseases with the highest burdens. It is possible to collect large-scale data on paediatric morbidity and mortality, to be used locally by health workers who gather it, and nationally for improving policy and practice, even in very resource-limited settings where ICD-10 coding systems such as those that exist in some high-income countries are not feasible or affordable. PMID:26489801

  10. A large mural nodule in branch duct intraductal papillary mucinous adenoma of the pancreas: a case report.

    Science.gov (United States)

    Haruki, Koichiro; Wakiyama, Shigeki; Futagawa, Yasuro; Shiba, Hiroaki; Misawa, Takeyuki; Yanaga, Katsuhiko

    2015-12-01

    Indications for resection of branch duct intraductal papillary mucinous neoplasms (IPMNs) remain controversial because of their low tendency to be malignant. Surgical resection should be recommended if any factors indicating malignancy are present. However, preoperative differentiation between benign and malignant tumors is very difficult, especially in cases of branch duct IPMNs. We herein report a case of branch duct intraductal papillary mucinous adenoma (IPMA) of the pancreas with a large mural nodule of 25 mm. A 74-year-old woman was admitted for examination and treatment for a cystic tumor in the head of the pancreas. Magnetic resonance cholangiopancreatography and computed tomography showed a cystic lesion, 50 mm in diameter, with an irregular mural nodule in the pancreatic head. Endoscopic ultrasonography demonstrated a multicystic tumor connected with the main pancreatic duct (MPD). The mural nodule had a diameter of 18 mm, and the MPD had a slight dilation of 6 mm. These findings suggested a high potential for malignancy. The patient underwent pancreaticoduodenectomy with lymph node dissection. The excised pancreas showed multiple cysts located in the branch pancreatic duct with a maximum diameter of 75 mm. The mural nodule had a maximum diameter of 25 mm. The tumor was diagnosed as an IPMA by pathological examination. After operation, the patient was discharged without any complications. Two years after resection, the patient remains in remission with no evidence of tumor recurrence.

  11. Spontaneous large renal pelvis hematoma in ureteropelvic junction obstruction presenting as an acute abdomen: Rare case report.

    Science.gov (United States)

    Sawant, Ajit; Kasat, Gaurav; Pawar, Prakash; Tamhankar, Ashwin

    2016-01-01

    Patients with ureteropelvic junction (UPJ) obstruction can present with flank pain or hematuria. We present 20-year-old male presenting with acute pain in lumbar and right fossa with tenderness and guarding, this case was clinically mimicking general surgical emergency. On computed tomography with urography and angiography, there was 15 cm × 11 cm × 10 cm size non-enhancing hyperdense lesion (average Hounsfield units - +64) in right renal pelvis suggestive of hematoma. Patient's diethylenetriaminepentaacetic acid diuretic renography was suggestive of right kidney glomerular function rate of 48.4 ml/min with the relative function of 43%, Peak to half peak was not achieved. The patient was managed by retrograde ureteropyelography and double J stenting. After 1 month, clot size decreased to 4 cm × 3 cm × 2 cm. The patient had undergone open reduction Anderson hynes dismembered pyeloplasty with the removal of pelvis clot after 6 weeks. We report the first case of UPJ obstruction presenting as an acute abdomen and spontaneous hematuria with large pelvis clot without rupture of the renal pelvis.

  12. Spontaneous large renal pelvis hematoma in ureteropelvic junction obstruction presenting as an acute abdomen: Rare case report

    Directory of Open Access Journals (Sweden)

    Ajit Sawant

    2016-01-01

    Full Text Available Patients with ureteropelvic junction (UPJ obstruction can present with flank pain or hematuria. We present 20-year-old male presenting with acute pain in lumbar and right fossa with tenderness and guarding, this case was clinically mimicking general surgical emergency. On computed tomography with urography and angiography, there was 15 cm × 11 cm × 10 cm size non-enhancing hyperdense lesion (average Hounsfield units - +64 in right renal pelvis suggestive of hematoma. Patient's diethylenetriaminepentaacetic acid diuretic renography was suggestive of right kidney glomerular function rate of 48.4 ml/min with the relative function of 43%, Peak to half peak was not achieved. The patient was managed by retrograde ureteropyelography and double J stenting. After 1 month, clot size decreased to 4 cm × 3 cm × 2 cm. The patient had undergone open reduction Anderson hynes dismembered pyeloplasty with the removal of pelvis clot after 6 weeks. We report the first case of UPJ obstruction presenting as an acute abdomen and spontaneous hematuria with large pelvis clot without rupture of the renal pelvis.

  13. Final Scientific/Technical Report: Electronics for Large Superconducting Tunnel Junction Detector Arrays for Synchrotron Soft X-ray Research

    Energy Technology Data Exchange (ETDEWEB)

    Warburton, William K

    2009-03-06

    Superconducting tunnel junction (STJ) detectors offer a an approach to detecting soft x-rays with energy resolutions 4-5 times better and at rates 10 faster than traditions semiconductor detectors. To make such detectors feasible, however, then need to be deployed in large arrays of order 1000 detectors, which in turn implies that their processing electronics must be compact, fully computer controlled, and low cost per channel while still delivering ultra-low noise performance so as to not degrade the STJ's performance. We report on our progress in designing a compact, low cost preamplifier intended for this application. In particular, we were able to produce a prototype preamplifier of 2 sq-cm area and a parts cost of less than $30 that matched the energy resolution of the best conventional system to date and demonstrated its ability to acquire an STJ I-V curve under computer control, the critical step for determining and setting the detectors' operating points under software control.

  14. Pineal Diffuse Large B-Cell Lymphoma Concomitant With Pituitary Prolactinoma: Possible Correlation Between 2 Distinguished Pathologies: A Case Report.

    Science.gov (United States)

    Kim, Yeong-Jin; Kim, Hee Kyung; Yang, Deok-Hwan; Jung, Shin; Noh, Myung-Giun; Lee, Jae-Hyuk; Lee, Kyung-Hwa; Moon, Kyung-Sub

    2016-02-01

    This is the first reported case of pineal lymphoma with concomitant prolactin-producing pituitary adenoma.A 51-year-old male experienced worsening headaches accompanied by nausea, diplopia, and memory loss for 1 month. Cranial nerve examination revealed bilateral upward gaze limitation with convergence impairment, which is known as Parinaud syndrome. Magnetic resonance images revealed a mass in the pineal gland with a coexisting mass within the enlarged sella fossa. Hormone analysis revealed hyperprolactinemia. The pineal mass was removed without injuring the hypothalamus, brain stem, or any neighboring vessels. Pathology examination confirmed the diagnosis of diffuse large B-cell lymphoma (DLBCL) involving the pineal gland. After further studies, the pineal lymphoma was determined to be a secondary tumor from a gastric primary tumor. The patient died 6 months after diagnosis due to systemic progression of DLBCL.Although the mechanistic link between hyperprolactinemia and lymphoma progression has not been clarified on a clinical basis, high prolactin levels may contribute to the rapid progression and therapeutic resistance of the lymphoma.

  15. Progressive multifocal cerebral infarction from intravascular large B cell lymphoma presenting in a man: a case report

    Directory of Open Access Journals (Sweden)

    Chotinaiwattarakul Wattanachai

    2011-01-01

    Full Text Available Abstract Introduction Intravascular lymphoma is rare, and may present as ischemic stroke. Diagnosis is difficult due to the non-specific presentation and lack of lymphadenopathy, thus leading to frequent instances of autopsy-proven diagnosis. To the best of our knowledge, this is the first report of progressive stroke from intravascular lymphoma diagnosed antemortem by random skin biopsy. Case presentation A 42-year-old Thai man presented to our hospital with progressive multifocal cerebral infarction. Despite taking aspirin (300 mg/day, his neurological symptoms worsened. During admission, he developed an unexplained fever and hypoxemia. Magnetic resonance angiography clearly showed patency of all cerebral arteries including the internal carotid and vertebrobasilar arteries. Echocardiography, an antiphospholipid antibody test, cerebrospinal fluid cytology and a bone marrow study were normal. Other laboratory test results showed an elevated lactate dehydrogenase level, nephrotic range proteinuria (3.91 g/day, hypoalbuminemia (1.9 g/dL, a very low high-density lipoprotein level (7 mg/dL and hypertriglyceridemia (353 mg/dL. Because of suspected vasculitis, pulse methylprednisolone was given with transiently minimal improvement. A random skin biopsy from both thighs revealed intravascular large B cell lymphoma. Chemotherapy was not given due to our patient having ventilator associated pneumonia. He died 10 days after the definite diagnosis was established. Conclusion One etiology of stroke is intravascular lymphoma, in which random skin biopsy can be helpful for antemortem diagnosis.

  16. Developing technology for large-scale production of forest chips. Wood Energy Technology Programme 1999-2003. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    The national Wood Energy Technology Programme was carried out by Tekes during the period 1999- 2003 to develop efficient technology for large- scale production of forest chips from small- sized trees and logging residues. This is the final report of the programme, and it outlines the general development of forest chip procurement and use during the programme period. In 2002, a sub-programme was established to address small-scale production and use of wood fuels. This sub-programme will continue to the end of 2004, and it is not reported here. The programme was coordinated by VTT Processes. As of January 2004, the programme consisted of 44 public research projects, 46 industrial or product development projects, and 29 demonstration projects. Altogether, 27 research organizations and 53 enterprises participated. The total cost of the programme was 42 M euro of which 13 M euro was provided by Tekes. The Ministry of Trade and Industry provided investment aid for the new technology employed in the demonstration projects. When the programme was launched at the end of the 1990s, the major barriers to the use of forest chips were high cost of production, shortage of reliable chip procurement organizations, and the unsatisfactory quality of fuel. Accordingly, the programme focused largely on these problems. In addition, upgrading of the fuel properties of bark was also studied. The production of forest chips must be adapted to the existing operating environment and infrastructure. In Finland, these are charaterized by rich bio-mass potential, a sophisticated and efficient organization for the procurement of industrial timber, a large capacity of heating and CHP plants to use wood fuels, the possibility to co-fire wood and peat, and the unreserved acceptance of society at large. A goal of Finnish energy and climate strategies is to use 5 million m3 (0.9 Mtoe) chips annually by 2010. The Wood Energy Technology Programme was an important link in the long chain of activities

  17. Large cell non-Hodgkin's lymphoma masquerading as renal carcinoma with inferior vena cava thrombosis: a case report

    Directory of Open Access Journals (Sweden)

    Weissman Alan

    2011-06-01

    Full Text Available Abstract Introduction Many cancers are associated with inferior vena cava (IVC obstruction, but very few cancers have the ability to propagate within the lumen of the renal vein or the IVC. Renal cell carcinoma is the most common of these cancers. Renal cancer with IVC extension has a high rate of recurrence and a low five year survival rate. Case presentation A 62-year-old Caucasian woman previously in good health developed the sudden onset of severe reflux symptoms and right-sided abdominal pain that radiated around the right flank. A subsequent ultrasound and CT scan revealed a right upper pole renal mass with invasion of the right adrenal gland, liver, left renal vein and IVC. This appeared to be consistent with stage III renal cancer with IVC extension. Metastatic nodules were believed to be present in the right pericardial region; the superficial anterior abdominal wall; the left perirenal, abdominal and pelvic regions; and the left adrenal gland. The pattern of these metastases, as well as the invasion of the liver by the tumor, was thought to be atypical of renal cancer. A needle biopsy of a superficial abdominal wall mass revealed a surprising finding: The malignant cells were diagnostic of large-cell, B-cell non-Hodgkin's lymphoma. The lymphoma responded dramatically to systemic chemotherapy, which avoided the need for nephrectomy. Conclusion Lymphomas only rarely progress via intraluminal vascular extension. We have been able to identify only one other case report of renal lymphoma with renal vein and IVC extension. While renal cancer would have been treated with radical nephrectomy and tumor embolectomy, large-cell B-cell lymphomas are treated primarily with chemotherapy, and nephrectomy would have been detrimental. It is important to remember that, rarely, other types of cancer arise from the kidney which are not derived from the renal tubular epithelium. These may be suspected if an atypical pattern of metastases or unusual

  18. Commutated automatic gain control system

    Science.gov (United States)

    Yost, S. R.

    1982-01-01

    The commutated automatic gain control (AGC) system was designed and built for the prototype Loran-C receiver is discussed. The current version of the prototype receiver, the Mini L-80, was tested initially in 1980. The receiver uses a super jolt microcomputer to control a memory aided phase loop (MAPLL). The microcomputer also controls the input/output, latitude/longitude conversion, and the recently added AGC system. The AGC control adjusts the level of each station signal, such that the early portion of each envelope rise is about at the same amplitude in the receiver envelope detector.

  19. Information Gains from Cosmological Probes

    CERN Document Server

    Grandis, S; Refregier, A; Amara, A; Nicola, A

    2015-01-01

    In light of the growing number of cosmological observations, it is important to develop versatile tools to quantify the constraining power and consistency of cosmological probes. Originally motivated from information theory, we use the relative entropy to compute the information gained by Bayesian updates in units of bits. This measure quantifies both the improvement in precision and the 'surprise', i.e. the tension arising from shifts in central values. Our starting point is a WMAP9 prior which we update with observations of the distance ladder, supernovae (SNe), baryon acoustic oscillations (BAO), and weak lensing as well as the 2015 Planck release. We consider the parameters of the flat $\\Lambda$CDM concordance model and some of its extensions which include curvature and Dark Energy equation of state parameter $w$. We find that, relative to WMAP9 and within these model spaces, the probes that have provided the greatest gains are Planck (10 bits), followed by BAO surveys (5.1 bits) and SNe experiments (3.1 ...

  20. Estimating the potential gains from mergers

    DEFF Research Database (Denmark)

    Bogetoft, Peter; Wang, Dexiang

    2005-01-01

    We introduce simple production economic models to estimate the potential gains from mergers. We decompose the gains into technical ef¿ciency, size (scale) and harmony (mix) gains, and we discuss alternative ways to capture these gains. We propose to approximate the production processes using...... the non-parametric. Data Envelopment Analysis (DEA) approach, and we use the resulting operational approach to estimate the potential gains from merging agricultural extension of¿ces in Denmark....

  1. Gain and loss learning differentially contribute to life financial outcomes.

    Directory of Open Access Journals (Sweden)

    Brian Knutson

    Full Text Available Emerging findings imply that distinct neurobehavioral systems process gains and losses. This study investigated whether individual differences in gain learning and loss learning might contribute to different life financial outcomes (i.e., assets versus debt. In a community sample of healthy adults (n = 75, rapid learners had smaller debt-to-asset ratios overall. More specific analyses, however, revealed that those who learned rapidly about gains had more assets, while those who learned rapidly about losses had less debt. These distinct associations remained strong even after controlling for potential cognitive (e.g., intelligence, memory, and risk preferences and socioeconomic (e.g., age, sex, ethnicity, income, education confounds. Self-reported measures of assets and debt were additionally validated with credit report data in a subset of subjects. These findings support the notion that different gain and loss learning systems may exert a cumulative influence on distinct life financial outcomes.

  2. Realized gains from block-plot coastal Douglas-fir trials in the northern Oregon Cascades

    Science.gov (United States)

    Terrence Z. Ye; Keith J.S. Jayawickrama; J. Bradley. St. Clair

    2010-01-01

    Realized gains for coastal Douglas-fir (Pseudotsuga menziesii var. menziesii) were evaluated using data collected from 15-year-old trees from five field trials planted in large block plots in the northern Oregon Cascades. Three populations with different genetic levels (elite--high predicted gain; intermediate--moderate predicted gain; and an...

  3. Calibration of the SH134-20 Standard Gain Horn

    DEFF Research Database (Denmark)

    Pivnenko, Sergey; Breinbjerg, Olav

    This report documents the measurement of the linearly polarized SH134-20 Standard Gain Horn. The measurement comprises on-axis gain, on-axis polarization characteristics, and reflection coefficient at 111 frequencies in the frequency range from 22-33 GHz. The measurement was carried out at the DT......-ESA Spherical Near-Field Antenna Test Facility in December 2012 for SE Laboratories, Santa Clara, CA, USA....

  4. Sudden gains in behavioural activation for depression.

    Science.gov (United States)

    Masterson, Ciara; Ekers, David; Gilbody, Simon; Richards, David; Toner-Clewes, Benjamin; McMillan, Dean

    2014-09-01

    Sudden gains have been linked to improved outcomes in cognitive behaviour therapy for depression. The relationship between sudden gains and outcome is less clear in other treatment modalities, including interpersonal psychotherapy and supportive expressive therapy, which may indicate different mechanisms of change between treatment modalities. The current study examined sudden gains in adults meeting diagnostic criteria for depression (N = 40) offered up to 12 sessions of behavioural activation treatment. Sudden gains were found in 42.5% of the sample. Sudden gains occurred early (median pre-gain session 2) and were related to outcome: those who experienced a sudden gain had significantly lower post-treatment scores on the PHQ-9. Furthermore, the proportion meeting the reliable and clinically significant change criteria at end of treatment was higher in the sudden gain group. These findings highlight the importance of understanding the mechanisms by which sudden gains relate to therapy outcome in behavioural activation.

  5. Mechanisms of intron gain and loss in Drosophila

    Directory of Open Access Journals (Sweden)

    Yenerall Paul

    2011-12-01

    Full Text Available Abstract Background It is widely accepted that orthologous genes have lost or gained introns throughout evolution. However, the specific mechanisms that generate these changes have proved elusive. Introns are known to affect nearly every level of gene expression. Therefore, understanding their mechanism of evolution after their initial fixation in eukaryotes is pertinent to understanding the means by which organisms develop greater regulation and complexity. Results To investigate possible mechanisms of intron gain and loss, we identified 189 intron gain and 297 intron loss events among 11 Drosophila species. We then investigated these events for signatures of previously proposed mechanisms of intron gain and loss. This work constitutes the first comprehensive study into the specific mechanisms that may generate intron gains and losses in Drosophila. We report evidence of intron gain via transposon insertion; the first intron loss that may have occurred via non-homologous end joining; intron gains via the repair of a double strand break; evidence of intron sliding; and evidence that internal or 5' introns may not frequently be deleted via the self-priming of reverse transcription during mRNA-mediated intron loss. Our data also suggest that the transcription process may promote or result in intron gain. Conclusion Our findings support the occurrence of intron gain via transposon insertion, repair of double strand breaks, as well as intron loss via non-homologous end joining. Furthermore, our data suggest that intron gain may be enabled by or due to transcription, and we shed further light on the exact mechanism of mRNA-mediated intron loss.

  6. Review of health and productivity gains from better IEQ

    Energy Technology Data Exchange (ETDEWEB)

    Fisk, William J.

    2000-08-01

    The available scientific data suggest that existing technologies and procedures can improve indoor environmental quality (IEQ) in a manner that significantly increases productivity and health. While there is considerable uncertainty in the estimates of the magnitudes of productivity gains that may be obtained, the projected gains are very large. For the U.S., the estimated potential annual savings and productivity gains are $6 to $14 billion from reduced respiratory disease, $2 to $4 billion from reduced allergies and asthma, $10 to $30 billion from reduced sick building syndrome symptoms, and $20 to $160 billion from direct improvements in worker performance that are unrelated to health. Productivity gains that are quantified and demonstrated could serve as a strong stimulus for energy efficiency measures that simultaneously improve the indoor environment.

  7. Silicon-erbium ytterbium silicate nanowire waveguides with optimized optical gain

    Science.gov (United States)

    Wang, Xiao-Xia; Zheng, Wei-Hao; Zhang, Qing-Lin; Zhu, Xiao-Li; Zhou, Hong; Zhuang, Xiu-Juan; Pan, An-Lian; Duan, Xiang-Feng

    2017-02-01

    Single-crystal erbium silicate nanowires have attracted considerable attention because of their high optical gain. In this work, we report the controlled synthesis of silicon-erbium ytterbium silicate core-shell nanowires and fine-tuning the erbium mole fraction in the shell from x = 0:3 to x = 1:0, which corresponds to changing the erbium concentration from 4:8 × 1021 to 1:6 × 1022 cm-3. By controlling and properly optimizing the composition of erbium and ytterbium in the nanowires, we can effectively suppress upconversion photoluminescence while simultaneously enhancing near-infrared emission. The composition-optimized nanowires have very long photoluminescence lifetimes and large emission cross-sections, which contribute to the high optical gain that we observed. We suspended these concentration-optimized nanowires in the air to measure and analyze their propagation loss and optical gain in the near-infrared communication band. Through systematic measurements using wires with different core sizes, we obtained a maximum net gain of 20±8 dB·mm-1, which occurs at a wavelength of 1534 nm, for a nanowire with a diameter of 600 nm and a silicon core diameter of 300 nm.

  8. Role of surface in high photoconductive gain measured in ZnO nanowire-based photodetector

    Energy Technology Data Exchange (ETDEWEB)

    Mallampati, Bhargav [University of North Texas, Department of Electrical Engineering (United States); Nair, S. V.; Ruda, H. E. [University of Toronto, Centre for Advanced Nanotechnology (Canada); Philipose, U., E-mail: usha.philipose@unt.edu [University of North Texas, Department of Physics (United States)

    2015-04-15

    On account of their large surface-to-volume ratio, nanowires contain an extremely high density of surface states which can lead to significantly enhanced photocarrier lifetimes resulting in persistent photoconductivity. There are reports that attribute the high photoconductive gain of ZnO nanowire-based photodetectors to hole trapping and de-trapping following oxygen adsorption and desorption from the nanowire surface. Through this work we provide experimental evidence of the role of surface and defects in carrier dynamics, resulting in enhanced photoresponse. ZnO nanowires with an average length of about 20 μm and diameters in the range of 60–80 nm were used in this experiment. Using intensity and temperature dependence of the rise and decay rate of photocurrent, we present a detailed analysis that provides an estimate of the activation energies of carrier trapping mechanisms. The high gain ZnO nanowire photodetector was sensitive to photoexcitation at or below 370 nm corresponding to the band-edge absorption profile of ZnO. At an incident wavelength of 370 nm and at a bias field of 5 kV/cm, it was found that the maximum responsivity is over 10{sup 5} A/W corresponding to an extremely high photoconductive gain of the order of 10{sup 6}. This corresponds to a normalized photoconductive gain of 4 × 10{sup −3} m{sup 2}V{sup −1}.

  9. Extensive intron gain in the ancestor of placental mammals

    Science.gov (United States)

    2011-01-01

    Background Genome-wide studies of intron dynamics in mammalian orthologous genes have found convincing evidence for loss of introns but very little for intron turnover. Similarly, large-scale analysis of intron dynamics in a few vertebrate genomes has identified only intron losses and no gains, indicating that intron gain is an extremely rare event in vertebrate evolution. These studies suggest that the intron-rich genomes of vertebrates do not allow intron gain. The aim of this study was to search for evidence of de novo intron gain in domesticated genes from an analysis of their exon/intron structures. Results A phylogenomic approach has been used to analyse all domesticated genes in mammals and chordates that originated from the coding parts of transposable elements. Gain of introns in domesticated genes has been reconstructed on well established mammalian, vertebrate and chordate phylogenies, and examined as to where and when the gain events occurred. The locations, sizes and amounts of de novo introns gained in the domesticated genes during the evolution of mammals and chordates has been analyzed. A significant amount of intron gain was found only in domesticated genes of placental mammals, where more than 70 cases were identified. De novo gained introns show clear positional bias, since they are distributed mainly in 5' UTR and coding regions, while 3' UTR introns are very rare. In the coding regions of some domesticated genes up to 8 de novo gained introns have been found. Intron densities in Eutheria-specific domesticated genes and in older domesticated genes that originated early in vertebrates are lower than those for normal mammalian and vertebrate genes. Surprisingly, the majority of intron gains have occurred in the ancestor of placentals. Conclusions This study provides the first evidence for numerous intron gains in the ancestor of placental mammals and demonstrates that adequate taxon sampling is crucial for reconstructing intron evolution. The

  10. Extensive intron gain in the ancestor of placental mammals

    Directory of Open Access Journals (Sweden)

    Kordiš Dušan

    2011-11-01

    Full Text Available Abstract Background Genome-wide studies of intron dynamics in mammalian orthologous genes have found convincing evidence for loss of introns but very little for intron turnover. Similarly, large-scale analysis of intron dynamics in a few vertebrate genomes has identified only intron losses and no gains, indicating that intron gain is an extremely rare event in vertebrate evolution. These studies suggest that the intron-rich genomes of vertebrates do not allow intron gain. The aim of this study was to search for evidence of de novo intron gain in domesticated genes from an analysis of their exon/intron structures. Results A phylogenomic approach has been used to analyse all domesticated genes in mammals and chordates that originated from the coding parts of transposable elements. Gain of introns in domesticated genes has been reconstructed on well established mammalian, vertebrate and chordate phylogenies, and examined as to where and when the gain events occurred. The locations, sizes and amounts of de novo introns gained in the domesticated genes during the evolution of mammals and chordates has been analyzed. A significant amount of intron gain was found only in domesticated genes of placental mammals, where more than 70 cases were identified. De novo gained introns show clear positional bias, since they are distributed mainly in 5' UTR and coding regions, while 3' UTR introns are very rare. In the coding regions of some domesticated genes up to 8 de novo gained introns have been found. Intron densities in Eutheria-specific domesticated genes and in older domesticated genes that originated early in vertebrates are lower than those for normal mammalian and vertebrate genes. Surprisingly, the majority of intron gains have occurred in the ancestor of placentals. Conclusions This study provides the first evidence for numerous intron gains in the ancestor of placental mammals and demonstrates that adequate taxon sampling is crucial for

  11. Large pneumothorax in blunt chest trauma: Is a chest drain always necessary in stable patients? A case report

    Directory of Open Access Journals (Sweden)

    Baig M. Idris

    2016-01-01

    Conclusion: Blunt traumatic large pneumothorax in a clinically stable patient can be managed conservatively. Current recommendations for tube placement may need to be reevaluated. This may reduce morbidity associated with chest tube thoracostomy.

  12. High-gain Yb:YAG amplifier for ultrashort pulse laser at high-average power

    Science.gov (United States)

    Vetrovec, John; Copeland, Drew A.; Litt, Amardeep S.; Du, Detao

    2016-03-01

    We report on a Yb:YAG laser amplifier for ultrashort pulse applications at kW-class average power. The laser uses two large-aperture, disk-type gain elements fabricated from composite ceramic YAG material, and a multi-pass extraction architecture to obtain high gain in a chirped-pulse amplification system. The disks are edge-pumped, thus allowing for reduced doping of host material with laser ions, which translates to lower lasing threshold and lower heat dissipation in the Yb:YAG material. The latter makes it possible to amplify a near diffraction-limited seed without significant thermo-optical distortions. This work presents results of testing the laser amplifier with relay optics configured for energy extraction with up to 40 passes through the disks. Applications for the ultrashort pulse laser amplifier include producing laser-induced plasma channel, laser material ablation, and laser acceleration of atomic particles.

  13. High-gain multipassed Yb:YAG amplifier for ultrashort pulse laser

    Science.gov (United States)

    Vetrovec, John; Copeland, Drew A.; Litt, Amardeep S.; Du, Detao

    2016-05-01

    We report on a Yb:YAG laser amplifier for ultrashort pulse applications at kW-class average power. The laser uses two large-aperture, disk-type gain elements fabricated from composite ceramic YAG material, and a multi-pass extraction architecture to obtain high gain in a chirped-pulse amplification system. The disks are edge-pumped, thus allowing for reduced doping of the host material with laser ions, which translates to lower lasing threshold and lower heat dissipation in the Yb:YAG material. The latter makes it possible to amplify a near diffraction-limited seed without significant thermo-optical distortions. This work presents results of testing the laser amplifier with relay optics and passive polarization switching configured for energy extraction with up to 40 passes through the disks. Applications for the ultrashort pulse laser amplifier include producing a laser-induced plasma channel, laser material ablation, and laser acceleration of atomic particles.

  14. Heuristic Portfolio Trading Rules with Capital Gain Taxes

    DEFF Research Database (Denmark)

    Fischer, Marcel; Gallmeyer, Michael

    strategy is not dominated out-of-sample by a variety of optimizing trading strategies, except the parametric portfolios of Brandt, Santa-Clara, and Valkanov (2009). With dividend and realization-based capital gain taxes, the welfare costs of the taxes are large with the cost being as large as 30% of wealth......We study the out-of-sample performance of portfolio trading strategies when an investor faces capital gain taxation and proportional transaction costs. Under no capital gain taxation and no transaction costs, we show that, consistent with DeMiguel, Garlappi, and Uppal (2009), a simple 1/N trading...... outperform a 1/N trading strategy augmented with a tax heuristic, not even the most tax- and transaction-cost efficient buy-and-hold strategy. Overall, the best strategy is 1/N augmented with a heuristic that allows for a fixed deviation in absolute portfolio weights. Our results show that the best trading...

  15. A child with colo-colonic intussusception due to a large colonic polyp: Case report and literature review

    Directory of Open Access Journals (Sweden)

    Toshiaki Takahashi

    2014-01-01

    Full Text Available Colo-colonic intussusception (CI due to a colonic polyp is a rarely reported cause of intestinal obstruction in school-aged children. Hydrostatic reduction (HR and endoscopic polypectomy are minimally invasive and technically feasible for treating CI. We report a case of CI and review the literature, focusing on the diagnosis and treatment.

  16. A novel antirecombinase gains PARIty

    DEFF Research Database (Denmark)

    Mankouri, Hocine W; Chu, Wai Kit; Hickson, Ian D

    2012-01-01

    In this issue, Moldovan et al. (2012) report the identification of PARI, a putative human ortholog of the yeast Srs2 protein, which potentially regulates homologous recombination repair via its ability to disrupt the function of RAD51....

  17. How Consistent are Publicly Reported Cytotoxicity Data? Large-Scale Statistical Analysis of the Concordance of Public Independent Cytotoxicity Measurements.

    Science.gov (United States)

    Cortés-Ciriano, Isidro; Bender, Andreas

    2016-01-01

    While increased attention is being paid to the impact of data quality in cell-line sensitivity and toxicology modeling, to date, no systematic study has evaluated the comparability of independent cytotoxicity measurements on a large-scale. Here, we estimate the experimental uncertainty of public cytotoxicity data from ChEMBL version 19. We applied stringent filtering criteria to assemble a curated data set comprised of pIC50 data for compound-cell line systems measured in independent laboratories. The estimated experimental uncertainty calculated was a mean unsigned error (MUE) value of 0.61-0.76, a median unsigned error (MedUE) value of 0.51-0.58, and a standard deviation of 0.76-1.00 pIC50 units. The experimental uncertainty (σE) estimated from all pairs of cytotoxicity measurements with a ΔpIC50 value lower than 2.5 was found to be 0.59-0.77 pIC50 units, and thus 21-60% and 21-26% higher than that of pKi and pIC50 data for ligand-protein data (σE =0.47-0.48 pKi units and σE =0.57-0.61 pIC50 units, respectively). The estimated σE value from the pairs of pIC50 values measured with metabolic assays was 0.98, whereas the σE value was found to be 0.69 when using the 1388 pIC50 pairs measured using exactly the same experimental setup. The maximum achievable Pearson correlation coefficient (RPearsonmax.2) of in silico models trained on cytotoxicity data from different laboratories was estimated to be 0.51-0.85, which is considerably different from the value of 1 corresponding to perfect predictions, hinting at the maximum performance one can expect also from computational cytotoxicity predictions. The lowest concordance between pairs of measurements was found for the drugs paclitaxel, methotrexate, zidovudine, and docetaxel, and for the cell lines HepG2, NCI-H460, L1210, and CCRF-CEM, hinting at particular sensitivity of those systems to experimental setups. The highest concordance was estimated for the compound-cell line system HL-60-etoposide (σE =0

  18. Factors influencing weight gain after renal transplantation.

    Science.gov (United States)

    Johnson, C P; Gallagher-Lepak, S; Zhu, Y R; Porth, C; Kelber, S; Roza, A M; Adams, M B

    1993-10-01

    Weight gain following renal transplantation occurs frequently but has not been investigated quantitatively. A retrospective chart review of 115 adult renal transplant recipients was used to describe patterns of weight gain during the first 5 years after transplantation. Only 23 subjects (21%) were overweight before their transplant. Sixty-six subjects (57%) experienced a weight gain of greater than or equal to 10%, and 49 subjects (43%) were overweight according to Metropolitan relative weight criteria at 1 year after transplantation. There was an inverse correlation between advancing age and weight gain, with the youngest patients (18-29 years) having a 13.3% weight gain and the oldest patients (age greater than 50 years) having the lowest gain of 8.3% at 1 year (P = 0.047). Black recipients experienced a greater weight gain than whites during the first posttransplant year (14.6% vs. 9.0%; P = 0.043), and maintained or increased this difference over the 5-year period. Men and women experienced comparable weight gain during the first year (9.5% vs. 12.1%), but women continued to gain weight throughout the 5-year study (21.0% total weight gain). The men remained stable after the first year (10.8% total weight gain). Recipients who experienced at least a 10% weight gain also increased their serum cholesterol (mean 261 vs. 219) and triglyceride (mean 277 vs. 159) levels significantly, whereas those without weight gain did not. Weight gain did not correlate with cumulative steroid dose, donor source (living-related versus cadaver), rejection history, pre-existing obesity, the number of months on dialysis before transplantation, or posttransplant renal function. Posttransplant weight gain is related mainly to demographic factors, not to treatment factors associated with the transplant. The average weight gain during the first year after renal transplantation is approximately 10%. This increased weight, coupled with changes in lipid metabolism, may be significant in

  19. Compulsive eating and weight gain related to dopamine agonist use.

    Science.gov (United States)

    Nirenberg, Melissa J; Waters, Cheryl

    2006-04-01

    Dopamine agonists have been implicated in causing compulsive behaviors in patients with Parkinson's disease (PD). These have included gambling, hypersexuality, hobbyism, and other repetitive, purposeless behaviors ("punding"). In this report, we describe 7 patients in whom compulsive eating developed in the context of pramipexole use. All of the affected patients had significant, undesired weight gain; 4 had other comorbid compulsive behaviors. In the 5 patients who lowered the dose of pramipexole or discontinued dopamine agonist treatment, the behavior remitted and no further weight gain occurred. Physicians should be aware that compulsive eating resulting in significant weight gain may occur in PD as a side-effect of dopamine agonist medications such as pramipexole. Given the known risks of the associated weight gain and obesity, further investigation is warranted.

  20. AN OVERVIEW OF THE DEVELOPMENT OF LOW GAIN FEEDBACK AND LOW-AND-HIGH GAIN FEEDBACK

    Institute of Scientific and Technical Information of China (English)

    Zongli LIN

    2009-01-01

    Low gain feedback refers to certain families of stabilizing state feedback gains that are parameterized in a scalar and go to zero as the scalar decreases to zero. Low gain feedback was initially proposed to achieve semi-global stabilization of linear systems subject to input saturation. It was then combined with high gain feedback in different ways for solving various control problems. The resulting feedback laws are referred to as low-and-high gain feedback. Since the introduction of low gain feedback in the context of semi-global stabilization of linear systems subject to input saturation,there has been effort to develop alternative methods for low gain design, to characterize key features of low gain feedback, and to explore new applications of the low gain and low-and-high gain feedback.This paper reviews the developments in low gain and low-and-high gain feedback designs.

  1. Static and Dynamic Regimes of Arbitrary Gain Compensation Single-Mode Laser Diodes

    CERN Document Server

    Tannous, C

    2001-01-01

    We report on a methodology for the evaluation of the DC characteristics, small-signal frequency response and large-signal dynamic response of carrier and photon density responses in semiconductor laser diodes. A single mode laser is considered and described with a pair of rate equations containing a novel non-linear gain compensation term depending on a single parameter that can be chosen arbitrarily. This approach can be applied to any type of solid-state laser as long as it is described by a set of rate equations.

  2. Gain scheduling using the Youla parameterization

    DEFF Research Database (Denmark)

    Niemann, Hans Henrik; Stoustrup, Jakob

    1999-01-01

    Gain scheduling controllers are considered in this paper. The gain scheduling problem where the scheduling parameter vector cannot be measured directly, but needs to be estimated is considered. An estimation of the scheduling vector has been derived by using the Youla parameterization. The use...... in connection with H_inf gain scheduling controllers....

  3. Self-Report Measures of the Home Learning Environment in Large Scale Research: Measurement Properties and Associations with Key Developmental Outcomes

    Science.gov (United States)

    Niklas, Frank; Nguyen, Cuc; Cloney, Daniel S.; Tayler, Collette; Adams, Raymond

    2016-01-01

    Favourable home learning environments (HLEs) support children's literacy, numeracy and social development. In large-scale research, HLE is typically measured by self-report survey, but there is little consistency between studies and many different items and latent constructs are observed. Little is known about the stability of these items and…

  4. High gain 1.3-μm GaInNAs SOA with fast gain dynamics and enhanced temperature stability

    Science.gov (United States)

    Fitsios, D.; Giannoulis, G.; Iliadis, N.; Korpijärvi, V.-M.; Viheriälä, J.; Laakso, A.; Dris, S.; Spyropoulou, M.; Avramopoulos, H.; Kanellos, G. T.; Pleros, N.; Guina, M.

    2014-03-01

    Semiconductor optical amplifiers (SOAs) are a well-established solution of optical access networks. They could prove an enabling technology for DataCom by offering extended range of active optical functionalities. However, in such costand energy-critical applications, high-integration densities increase the operational temperatures and require powerhungry external cooling. Taking a step further towards improving the cost and energy effectiveness of active optical components, we report on the development of a GaInNAs/GaAs (dilute nitride) SOA operating at 1.3μm that exhibits a gain value of 28 dB and combined with excellent temperature stability owing to the large conduction band offset between GaInNAs quantum well and GaAs barrier. Moreover, the characterization results reveal almost no gain variation around the 1320 nm region for a temperature range from 20° to 50° C. The gain recovery time attained values as short as 100 ps, allowing implementation of various signal processing functionalities at 10 Gb/s. The combined parameters are very attractive for application in photonic integrated circuits requiring uncooled operation and thus minimizing power consumption. Moreover, as a result of the insensitivity to heating issues, a higher number of active elements can be integrated on chip-scale circuitry, allowing for higher integration densities and more complex optical on-chip functions. Such component could prove essential for next generation DataCom networks.

  5. AN UNUSUALLY LARGE (5kg BENIGN OVARIAN CYST REMOV ED FROM A POSTMENOPAUSAL WOMAN: A CASE REPORT

    Directory of Open Access Journals (Sweden)

    Amaraja

    2015-05-01

    Full Text Available A 47 yr s . old woman presented with a huge abdominal lump which was cystic. Ultra - sonography confirmed a large cystic tumour without any solid component. CT displayed large loculus of fluid with a few septae filled with clea r homogenous fluid. All tumour makers were within normal limits. Here we present an unusual case in which, during e xploratory laparotomy, right ovarian cyst was removed followed by hysterectomy and bilateral salpingo o op ho erectomy. Cytology confirmed the b enign nature of the cyst with a diagnosis of simple serous cystadenoma with no evidence of malignancy.

  6. Insights gained from aging research

    Energy Technology Data Exchange (ETDEWEB)

    Blahnik, D.E.; Casada, D.A.; Edson, J.L.; Fineman, D.L.; Gunther, W.E.; Haynes, H.D.; Hoopingarner, K.R.; Jacobus, M.J.; Jarrell, D.B.; Kryter, R.C.; Magelby, H.L.; Murphy, G.A.; Subudhi, M.M.

    1992-03-01

    The US NRC Office of Nuclear Regulatory Research has implemented hardware-oriented engineering research programs to identify and resolve technical issues related to the aging of systems, structures, and components (SSCs) in operating nuclear power plants. This report provides a summary of those research results which have been compiled and published in NUREGS and related technical reports. The systems, components and structures that have been studied are organized by alphabetical order. The research results summary on the SSCs is followed by an assessment guide to emphasize inspection techniques which may be useful for detecting aging degradation in nuclear power plants. This report will be updated periodically to reflect new research results on these or other SSCs.

  7. Analytical Foundations of Gain Scheduling

    Science.gov (United States)

    1993-03-15

    on ,his topic has continued. We have also been considering possibilities for using ideas from the exact linearization theory, including the theory of...effort. However it was deemed important as a second-priority effort, in part to maintain contact with the large theoretical effort in exact ... linearization approaches. Finally, I have included in the list of publications my new book [9] on linear system theory. While AFOSR did not directly support

  8. Use of EndoVac System for Aspiration of Exudates from a Large Periapical Lesion: A Case Report.

    Science.gov (United States)

    Keleş, Ali; Alçin, Hatice

    2015-10-01

    Large cyst-like periapical lesions can heal after nonsurgical root canal treatment. Decreasing the hydrostatic pressure within a periapical lesion can be achieved with the aspiration technique by using EndoVac when there is drainage of cystic fluid through the canals. Clinical examination of a 21-year-old male patient revealed a large periapical lesion extending from the distal aspect of tooth #26 and reaching the mesial surface of tooth #22. During root canal treatment of teeth #23, #24, and #26, serous exudate drained from the root canal of tooth #24. The MacroCannula component of EndoVac apical negative pressure irrigation system was used to aspirate the inflammatory fluid. The technique produces a vacuum effect in the periapical region through the root canal, which facilitates evacuation of large amounts of exudate. Two-year clinical and radiographic examinations revealed resolution of the mandibular radiolucency, and the adjacent tooth #25 retained its vitality. The healing of a large periapical lesion can be achieved by the correct diagnosis and the proper treatment approach, without the need for surgery. EndoVac negative irrigation system might be useful for intracanal aspiration of exudates. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  9. 26 CFR 31.6053-3 - Reporting by certain large food or beverage establishments with respect to tips.

    Science.gov (United States)

    2010-04-01

    ... services along with food or beverages for a combined price, such as a “package deal” for food and lodging... its full service food or beverage operations. (7) Large food or beverage establishment. A food or... employee” is an employee who provides services in connection with the provision of food or beverages. Such...

  10. Small signal gain in DPAL systems

    Science.gov (United States)

    Galbally-Kinney, Kristin L.; Maser, Daniel L.; Kessler, William J.; Rawlins, Wilson T.; Davis, Steven J.

    2011-03-01

    In this paper we describe a platform for small signal gain measurements for alkali atom laser systems based on the DPAL excitation method. We present initial results that clearly show the transition from absorption on the alkali atom D1 lines in Cs and Rb to optical transparency and positive gain. The achievement of optical gain is critically dependent upon alkali cell conditions and collision partners. We also present the first spatially resolved gain measurements in a DPAL system. The small signal gain methods described will be valuable tools for power scaling of these laser systems.

  11. Gain flattened distributed fiber raman amplifiers

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    An S band and a C band distributed fiber Raman amplifiers (DFRAs) with flattened gain and compensated dispersion have been studied and implemented with 1 427 nm and 1 455 nm mono-wavelength fiber Raman lasers as the pumped sources respectively. The gain of single-wave pumped S band and C band can reach 10 dB and 15 dB respectively. And a 50 nm gain flattened width was successfully obtained by using a chirp fiber Bragg grating (CFBG) gain flattened filter with gain ripple of 0.6 dB. The C band DFRA has been applied to CDMA wireless communication system successfully.

  12. Weight Gain, Obesity, and Psychotropic Prescribing

    Directory of Open Access Journals (Sweden)

    Nikhil Nihalani

    2011-01-01

    Full Text Available A majority of psychiatric medications are known to generate weight gain and ultimately obesity in some patients. There is much speculation about the prevalence of weight gain and the degree of weight gain during acute and longitudinal treatment with these agents. There is newer literature looking at the etiology of this weight gain and the potential treatments being used to alleviate this side effect. The authors undertook a comprehensive literature review in order to present epidemiology, etiology, and treatment options of weight gain associated with antipsychotics, mood stabilizers, and antidepressants.

  13. Health care reform: perspectives from large employers.

    Science.gov (United States)

    Darling, Helen

    2010-06-01

    Recently enacted health reform legislation will have mostly positive effects on large employers, as millions more Americans gain access to affordable insurance and, potentially, primary care. But the law will impose new administrative burdens and financing costs on employers, while raising concerns about provisions that could allow their lower-wage employees to obtain coverage through insurance exchanges. Given the need to restrain the rate of growth of health spending, the private sector, especially large employers, must collaborate with the public sector to drive delivery system reform. And every public program and exchange should appoint a chief value officer who reports quarterly on spending, cost drivers, and potential ways to contain costs.

  14. Patient-reported safety incidents in older patients with long-term conditions: a large cross-sectional study.

    Science.gov (United States)

    Panagioti, Maria; Blakeman, Thomas; Hann, Mark; Bower, Peter

    2017-05-30

    Increasing evidence suggests that patient safety is a serious concern for older patients with long-term conditions. Despite this, there is a lack of research on safety incidents encountered by this patient group. In this study, we sought to examine patient reports of safety incidents and factors associated with reports of safety incidents in older patients with long-term conditions. The baseline cross-sectional data from a longitudinal cohort study were analysed. Older patients (n=3378 aged 65 years and over) with a long-term condition registered in general practices were included in the study. The main outcome was patient-reported safety incidents including availability and appropriateness of medical tests and prescription of wrong types or doses of medication. Binary univariate and multivariate logistic regression analyses were undertaken to examine factors associated with patient-reported safety incidents. Safety incidents were reported by 11% of the patients. Four factors were significantly associated with patient-reported safety incidents in multivariate analyses. The experience of multiple long-term conditions (OR=1.09, 95% CI 1.05 to 1.13), a probable diagnosis of depression (OR=1.36, 95% CI 1.06 to 1.74) and greater relational continuity of care (OR=1.28, 95% CI 1.08 to 1.52) were associated with increased odds for patient-reported safety incidents. Perceived greater support and involvement in self-management was associated with lower odds for patient-reported safety incidents (OR=0.95, 95% CI 0.93 to 0.97). We found that older patients with multimorbidity and depression are more likely to report experiences of patient safety incidents. Improving perceived support and involvement of patients in their care may help prevent patient-reported safety incidents. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  15. Surgical management of a large complex odontoma of the mandibular angle-ramus region through intra-oral buccal approach--A case report.

    Science.gov (United States)

    Ogunlewe, M O; Adeyemo, W L; Ladeinde, A L; Bamgbose, B O; Ajayi, O F

    2005-12-01

    Large complex odontomas of the jaws are rare. A report of a large complex odontoma of the mandibular angle-ramus region enucleated through intra-oral buccal approach is presented. A review of the literature on different modalities of treatment is also undertaken. A large expansile complex odontoma of the angle-ramus region of the mandible was excised through an intraoral buccal approach under general anaesthesia. Recovery and immediate post-operative period were uneventful. There was no altered sensation in the distribution of the inferior alveolar nerve and lingual nerve; and wound healing was satisfactory. Post-operative radiograph 2 years after the operation showed satisfactory bone regeneration. Intraoral buccal approach to large complex odontomas of the angle-ramus region of the mandible is a relatively safe procedure with minimal complication.

  16. Weight Gain and Obesity in Infants and Young Children Exposed to Prolonged Antibiotic Prophylaxis.

    Science.gov (United States)

    Edmonson, M Bruce; Eickhoff, Jens C

    2017-02-01

    An association between antibiotic use and excessive weight gain or obesity in healthy infants and young children has been reported, but evidence is inconsistent and based on observational studies of growth in relation to incidental antibiotic exposures. To evaluate whether prolonged antibiotic exposure is associated with weight gain in children participating in a clinical trial of antibiotic prophylaxis to prevent recurrent urinary tract infection. Secondary analysis of data from the Randomized Intervention for Children With Vesicoureteral Reflux Study, a 2-year randomized clinical trial that enrolled participants from 2007 to 2011. All 607 children who were randomized to receive antibiotic (n = 302) or placebo (n = 305) were included. Children with urinary tract anomalies, premature birth, or major comorbidities were excluded from participation. Trimethoprim-sulfamethoxazole or placebo taken orally, once daily, for 2 years. Weight gain as measured by change in weight-for-age z score from baseline to the end-of-study visit at 24 months. Secondary outcomes included weight gain at 6, 12, and 18 months and the prevalence of overweight or obesity at 24 months. Participants had a median age of 12 months (range, 2-71 months) and 558 of 607 (91.9%) were female. Anthropometric data were complete at the 24-month visit for 428 children (214 in the trimethoprim-sulfamethoxazole group and 214 in the placebo group). Weight gain in the trimethoprim-sulfamethoxazole group and the placebo group was similar (mean [SD] change in weight-for-age z score: +0.14 [0.83] and +0.18 [0.85], respectively; difference, -0.04 [95% CI, -0.19 to 0.12]; P = .65). There was no significant difference in weight gain at 6, 12, or 18 months or in the prevalence of overweight or obesity at 24 months (24.8% vs 25.7%; P = .82). Subgroup analyses showed no significant interaction between weight gain effect and age, sex, history of breastfeeding, prior antibiotic use, adherence to study

  17. Exercise during pregnancy and its association with gestational weight gain.

    Science.gov (United States)

    Harris, Shericka T; Liu, Jihong; Wilcox, Sara; Moran, Robert; Gallagher, Alexa

    2015-03-01

    We examined the association between exercise during pregnancy and meeting gestational weight gain recommendations. Data came from the 2009 South Carolina Pregnancy Risk Assessment Monitoring System (n = 856). Women reported their participation in exercise/sports activities before and during pregnancy, including the number of months and types of exercise. We developed an exercise index (EI), the product of the number of months spent in exercise and average metabolic equivalents for specific exercise. The 2009 Institute of Medicine's guideline was used to categorize gestational weight gain into three classes: inadequate, adequate, and excessive. Multinomial logistic regression models were used to adjust for confounders. Over 46 % of women exceeded the recommended weight gain during pregnancy. Nearly one third (31.9 %) of women reported exercising ≥3 times a week at any time during pregnancy. Compared to women who did not report this level of exercise during pregnancy, exercising women were more likely to meet gestational weight gain recommendations (32.7 vs. 18.7 %) and had a lower odds of excessive gestational weight gain [adjusted odds ratio (AOR) 0.43, 95 % confidence interval 0.24-0.78]. Women with an EI above the median value of those women who exercised or women who exercised ≥3 times a week for 6-9 months during pregnancy had lower odds of excessive gestational weight gain (AOR for EI 0.20, 0.08-0.49; AOR for months 0.26, 0.12-0.56, respectively). Our findings support the need to promote or increase exercise during pregnancy to reduce the high proportion of women who are gaining excessive weight.

  18. Universality of Coherent Raman Gain Suppression in Gas-Filled Broadband-Guiding Photonic Crystal Fibers

    Science.gov (United States)

    Hosseini, P.; Mridha, M. K.; Novoa, D.; Abdolvand, A.; Russell, P. St. J.

    2017-03-01

    As shown in the early 1960s, the gain in stimulated Raman scattering (SRS) is drastically suppressed when the rate of creation of phonons (via a pump-to-Stokes conversion) is exactly balanced by the rate of phonon annihilation (via a pump-to-anti-Stokes conversion). This occurs when the phonon coherence waves—synchronized vibrations of a large population of molecules—have identical propagation constants for both processes; i.e., they are phase-velocity matched. As recently demonstrated, hydrogen-filled photonic crystal fiber pumped in the vicinity of its zero-dispersion wavelength provides an ideal system for observing this effect. Here we report that Raman gain suppression is actually a universal feature of SRS in gas-filled hollow-core fibers and that it can strongly impair SRS even when the phase mismatch is high, particularly at high pump powers when it is normally assumed that nonlinear processes become more (not less) efficient. This counterintuitive result means that intermodal stimulated Raman scattering (for example, between LP01 and LP11 core modes) begins to dominate at high power levels. The results reported have important implications for fiber-based Raman shifters, amplifiers, or frequency combs, especially for operation in the ultraviolet, where the Raman gain is much higher.

  19. Treatment of a large periradicular defect using guided tissue regeneration: A case report of 2 years follow-up and surgical re-entry.

    Science.gov (United States)

    Gurav, Abhijit Ningappa; Shete, Abhijeet Rajendra; Naiktari, Ritam

    2015-01-01

    Periradicular (PR) bone defects are common sequelae of chronic endodontic lesions. Sometimes, conventional root canal therapy is not adequate for complete resolution of the lesion. PR surgeries may be warranted in such selected cases. PR surgery provides a ready access for the removal of pathologic tissue from the periapical region, assisting in healing. Recently, the regeneration of the destroyed PR tissues has gained more attention rather than repair. In order to promote regeneration after apical surgery, the principle of guided tissue regeneration (GTR) has proved to be useful. This case presents the management of a large PR lesion in a 42-year-old male subject. The PR lesion associated with 21, 11 and 12 was treated using GTR membrane, fixated with titanium minipins. The case was followed up for 2 years radiographically, and a surgical re-entry confirmed the re-establishment of the lost labial plate. Thus, the principle of GTR may immensely improve the clinical outcome and prognosis of an endodontically involved tooth with a large PR defect.

  20. Treatment of a large periradicular defect using guided tissue regeneration: A case report of 2 years follow-up and surgical re-entry

    Directory of Open Access Journals (Sweden)

    Abhijit Ningappa Gurav

    2015-01-01

    Full Text Available Periradicular (PR bone defects are common sequelae of chronic endodontic lesions. Sometimes, conventional root canal therapy is not adequate for complete resolution of the lesion. PR surgeries may be warranted in such selected cases. PR surgery provides a ready access for the removal of pathologic tissue from the periapical region, assisting in healing. Recently, the regeneration of the destroyed PR tissues has gained more attention rather than repair. In order to promote regeneration after apical surgery, the principle of guided tissue regeneration (GTR has proved to be useful. This case presents the management of a large PR lesion in a 42-year-old male subject. The PR lesion associated with 21, 11 and 12 was treated using GTR membrane, fixated with titanium minipins. The case was followed up for 2 years radiographically, and a surgical re-entry confirmed the re-establishment of the lost labial plate. Thus, the principle of GTR may immensely improve the clinical outcome and prognosis of an endodontically involved tooth with a large PR defect.

  1. Treatment of a large periradicular defect using guided tissue regeneration: A case report of 2 years follow-up and surgical re-entry

    Science.gov (United States)

    Gurav, Abhijit Ningappa; Shete, Abhijeet Rajendra; Naiktari, Ritam

    2015-01-01

    Periradicular (PR) bone defects are common sequelae of chronic endodontic lesions. Sometimes, conventional root canal therapy is not adequate for complete resolution of the lesion. PR surgeries may be warranted in such selected cases. PR surgery provides a ready access for the removal of pathologic tissue from the periapical region, assisting in healing. Recently, the regeneration of the destroyed PR tissues has gained more attention rather than repair. In order to promote regeneration after apical surgery, the principle of guided tissue regeneration (GTR) has proved to be useful. This case presents the management of a large PR lesion in a 42-year-old male subject. The PR lesion associated with 21, 11 and 12 was treated using GTR membrane, fixated with titanium minipins. The case was followed up for 2 years radiographically, and a surgical re-entry confirmed the re-establishment of the lost labial plate. Thus, the principle of GTR may immensely improve the clinical outcome and prognosis of an endodontically involved tooth with a large PR defect. PMID:26941526

  2. Mathematical methods in material science and large scale optimization workshops: Final report, June 1, 1995-November 30, 1996

    Energy Technology Data Exchange (ETDEWEB)

    Friedman, A. [Minnesota Univ., Minneapolis, MN (United States). Inst. for Mathematics and Its Applications

    1996-12-01

    The summer program in Large Scale Optimization concentrated largely on process engineering, aerospace engineering, inverse problems and optimal design, and molecular structure and protein folding. The program brought together application people, optimizers, and mathematicians with interest in learning about these topics. Three proceedings volumes are being prepared. The year in Materials Sciences deals with disordered media and percolation, phase transformations, composite materials, microstructure; topological and geometric methods as well as statistical mechanics approach to polymers (included were Monte Carlo simulation for polymers); miscellaneous other topics such as nonlinear optical material, particulate flow, and thin film. All these activities saw strong interaction among material scientists, mathematicians, physicists, and engineers. About 8 proceedings volumes are being prepared.

  3. Repair of large frontal temporal parietal skull defect with digitally reconstructed titanium mesh: a report of 20 cases

    Directory of Open Access Journals (Sweden)

    Gang-ge CHENG

    2013-09-01

    Full Text Available Objective To explore the clinical effect and surgical technique of the repair of large defect involving frontal, temporal, and parietal regions using digitally reconstructed titanium mesh. Methods Twenty patients with large frontal, temporal, and parietal skull defect hospitalized in Air Force General Hospital from November 2006 to May 2012 were involved in this study. In these 20 patients, there were 13 males and 7 females, aged 18-58 years (mean 39 years, and the defect size measured from 7.0cm×9.0cm to 11.5cm×14.0cm (mean 8.5cm×12.0cm. Spiral CT head scan and digital three-dimensional reconstruction of skull were performed in all the patients. The shape and geometric size of skull defect was traced based on the symmetry principle, and then the data were transferred into digital precision lathe to reconstruct a titanium mesh slightly larger (1.0-1.5cm than the skull defect, and the finally the prosthesis was perfected after pruning the border. Cranioplasty was performed 6-12 months after craniotomy using the digitally reconstructed titanium mesh. Results The digitally reconstructed titanium mesh was used in 20 patients with large frontal, temporal, parietal skull defect. The surgical technique was relatively simple, and the surgical duration was shorter than before. The titanium mesh fit to the defect of skull accurately with satisfactory molding effect, good appearance and symmetrical in shape. No related complication was found in all the patients. Conclusion Repair of large frontal, temporal, parietal skull defect with digitally reconstructed titanium mesh is more advantageous than traditional manual reconstruction, and it can improve the life quality of patients.

  4. Severe phenotype in an apparent homozygosity caused by a large deletion in the CFTR gene: a case report.

    Science.gov (United States)

    Martins, Raisa da Silva; Fonseca, Ana Carolina Proença; Acosta, Franklyn Enrique Samudio; Folescu, Tania Wrobel; Higa, Laurinda Yoko Shinzato; Sad, Izabela Rocha; Chaves, Célia Regina Moutinho de Miranda; Cabello, Pedro Hernan; Cabello, Giselda Maria Kalil

    2014-08-30

    Over 1900 mutations have been identified in the cystic fibrosis conductance transmembrane regulator gene, including single nucleotide substitutions, insertions, and deletions. Unidentified mutations may still lie in introns or in regulatory regions, which are not routinely investigated, or in large genomic deletions, which are not revealed by conventional molecular analysis. The apparent homozygosity for a rare, cystic fibrosis conductance transmembrane regulator mutation screened by standard molecular analysis should be further investigated to confirm if the mutation is in fact homozygous. We describe a patient presenting with an apparent homozygous S4X mutation. A 13-year-old female patient of African descent with clinical symptoms of classic cystic fibrosis and a positive sweat test (97 mEq/L, diagnosed at age 3 years) presented with pancreatic insufficiency and severe pulmonary symptoms (initial lung colonization with Pseudomonas aeruginosa at age 4 years; forced vital capacity: 69%; forced expiratory volume: 51%; 2011). Furthermore, she developed severe acute lung disease and recurrent episodes of dehydration requiring hospitalization. The girl carried the CFTR mutation S4X in apparent homozygosity. However, further analysis revealed a large deletion in the second allele that included the region of the mutation. The deletion that we describe includes nucleotides 120-142, which correspond to a loss of 23 nucleotides that abolishes the normal translation initiation codon. This study reiterates the view that large, cystic fibrosis conductance transmembrane regulator deletions are an important cause of severe cystic fibrosis and emphasizes the importance of including large deletions/duplications in cystic fibrosis conductance transmembrane regulator diagnostic tests.

  5. Isolated colonic schwannoma in the ascending colon: A case report and literature review of Schwannomas in the large intestine

    Energy Technology Data Exchange (ETDEWEB)

    Nam, In Chul; Lee, Ye Daum; Kim, Seung Ho; Yoon, Jung Hee; Baek, Hye Jin; Lee, Kwang Hwi; Nam, Kyung Han [Haeundae Paik Hospital, Inje University College of Medicine, Busan (Korea, Republic of)

    2015-05-15

    Schwannomas are benign mesenchymal spindle cell tumors arising from the Schwann cells that form the peripheral neural sheath. Several recent studies indicate that although reports of gastrointestinal schwannomas have increased with advanced technological developments in immunohistochemical staining, isolated colonic schwannomas are extremely rare. Moreover, it is known to be somewhat difficult to diagnose colonic schwannoma before surgical operation. In this paper, we report a case of isolated schwannoma that was incidentally discovered in the ascending colon, along with a review of few recent literatures.

  6. Descriptor-variable approach to modeling and optimization of large-scale systems. Final report, March 1976--February 1979

    Energy Technology Data Exchange (ETDEWEB)

    Stengel, D N; Luenberger, D G; Larson, R E; Cline, T B

    1979-02-01

    A new approach to modeling and analysis of systems is presented that exploits the underlying structure of the system. The development of the approach focuses on a new modeling form, called 'descriptor variable' systems, that was first introduced in this research. Key concepts concerning the classification and solution of descriptor-variable systems are identified, and theories are presented for the linear case, the time-invariant linear case, and the nonlinear case. Several standard systems notions are demonstrated to have interesting interpretations when analyzed via descriptor-variable theory. The approach developed also focuses on the optimization of large-scale systems. Descriptor variable models are convenient representations of subsystems in an interconnected network, and optimization of these models via dynamic programming is described. A general procedure for the optimization of large-scale systems, called spatial dynamic programming, is presented where the optimization is spatially decomposed in the way standard dynamic programming temporally decomposes the optimization of dynamical systems. Applications of this approach to large-scale economic markets and power systems are discussed.

  7. Fundamental tests and operational suitability tests in the field. Large diameter boring with water jets (2nd report)

    Energy Technology Data Exchange (ETDEWEB)

    Oga, Kotaro; Higuchi, Kiyoshi; Uehara, Masabumi

    1987-09-25

    The application test of large diameter boring in coal seams assisted with water jet was made and two plunger pumps were used. Maximum hydraulic pressure were 300Kg/cm/sup 2/ and 700Kg/cm/sup 2/ and maximum flow rate were 140l/min and 47l/min respectively. Jet water was injected from each nozzle through the pressure resistant hose. Basic test and application test results in Taiheiyo and Akabira mines were summarized as follows: lengths of boreholes were 38 to 78 m and bored diameters were 30 to 70cm. The bored diameter depended on the coal zone hardness and the in-situ stress and indicated similar tendency to the previous large diameter boring. Boring speed was 0.14 to 0.33m/min in case of high velocity jet stream and 0.09m/min at the large diameter boring. Two miners can set and withdraw the boring equipments including the drilling work. (7 figs, 8 tabs, 6 refs)

  8. Peer assessment in large undergraduate classes: an evaluation of a procedure for marking laboratory reports and a review of related practices.

    Science.gov (United States)

    Harris, Judy R

    2011-06-01

    This study provides evidence that peer marking can be a reliable tool for assessing laboratory reports in large cohorts. It was conducted over a 4-yr period with first-year undergraduates (∼180 students/cohort) taking a mammalian physiology course, but the procedure adopted would be applicable to any other laboratory-based discipline. The process was found to be efficient in staff time, enabling a summative practical report to be marked in peer-assessed reports were marked by a single member of staff, there was excellent correlation between peer and staff marks (r = 0.96-0.98), although peer-awarded marks exceeded staff marks by an average of 2.5-3.0%. The validity of peer marking was independent of both the sex of the marker and the staff score awarded to the marker for the same piece of work. Feedback from students was largely positive; they reported that the procedure adopted was effective in increasing their understanding of the underlying physiology and contributed to their understanding of best practice in presenting a laboratory report. Seventy percent of students agreed that it was acceptable for peer assessment to contribute a small (up to 5%) component of the overall mark for the course. The results are discussed in relation to other reports of peer marking, particularly when used to assess an academic product or process in a scientific discipline.

  9. Self-reported Disability in Patients with Inflammatory Bowel Disease Largely Determined by Disease Activity and Illness Perceptions

    NARCIS (Netherlands)

    van der Have, Mike; Fidder, Herma H.; Leenders, Max; Kaptein, Ad A.; van der Valk, Mirthe E.; van Bodegraven, Ad A.; Dijkstra, Gerard; de Jong, Dirk J.; Pierik, Marieke; Ponsioen, Cyriel Y.; van der Meulen-de Jong, Andrea E.; van der Woude, C. Janneke; van de Meeberg, Paul C.; Romberg-Camps, Marielle J. L.; Clemens, Cees H. M.; Jansen, Jeroen M.; Mahmmod, Nofel; Bolwerk, Clemens J. M.; Vermeijden, J. Reinoud; Siersema, Peter D.; Oldenburg, Bas

    Background:The inflammatory bowel disease (IBD) disability index has recently been introduced to measure patients' physical, psychological, familial, and social limitations associated with IBD. We assessed factors related to self-reported disability and the relationship between disability and direct

  10. Final Report on the “New Directions in the Variational Multiscale Formulation of Large Eddy Simulation of Turbulence”

    Energy Technology Data Exchange (ETDEWEB)

    Oberai, Assad A [Rensselaer Polytechnic Instistute

    2013-07-16

    In the report we present a summary of the new models and algorithms developed by the PI and the students supported by this grant. These developments are described in detail in ten peer-reviewed journal articles that acknowledge support from this grant.

  11. Intestinal Microbiota and Weight-Gain in Preterm Neonates

    Science.gov (United States)

    Arboleya, Silvia; Martinez-Camblor, Pablo; Solís, Gonzalo; Suárez, Marta; Fernández, Nuria; de los Reyes-Gavilán, Clara G.; Gueimonde, Miguel

    2017-01-01

    The involvement of the gut microbiota on weight-gain and its relationship with childhood undernutrition and growth has been reported. Thus, the gut microbiota constitutes a potential therapeutic target for preventing growth impairment. However, our knowledge in this area is limited. In this study we aimed at evaluating the relationship among early microbiota, growth, and development in preterm infants. To this end we assessed the levels of specific microorganisms by qPCR, and those of short chain fatty acids by mean of gas-chromatography, in feces from 63 preterm newborns and determined their weight-gain during the first months. The statistical analyses performed indicate an influence of the intestinal microbiota in weight-gain, with the levels of some microorganisms showing a significant association with the weight-gain of the infant. The levels of specific microbial groups during the first days of life were found to affect weight gain by the age of 1 month. Moreover, clustering of the infants on the basis of the microbiota composition at 1 month of age rendered groups which showed differences in weight z-scores. Our results suggest an association between the gut microbiota composition and weight-gain in preterm infants at early life and point out potential microbial targets for favoring growth and maturation in these infants. PMID:28228752

  12. Reliability of reporting of HIV status and antiretroviral therapy usage during verbal autopsies: a large prospective study in rural Malawi

    Directory of Open Access Journals (Sweden)

    Estelle M. Mclean

    2016-06-01

    Full Text Available Objective: Verbal autopsies (VAs are interviews with a relative or friend of the deceased; VAs are a technique used in surveillance sites in many countries with incomplete death certification. The goal of this study was to assess the accuracy and validity of data on HIV status and antiretroviral therapy (ART usage reported in VAs and their influence on physician attribution of cause of death. Design: This was a prospective cohort study. Methods: The Karonga Health and Demographic Surveillance Site monitors demographic events in a population in a rural area of northern Malawi; a VA is attempted on all deaths reported. VAs are reviewed by clinicians, who, with additional HIV test information collected pre-mortem, assign a cause of death. We linked HIV/ART information reported by respondents during adult VAs to database information on HIV testing and ART use and analysed agreement using chi-square and kappa statistics. We used multivariable logistic regression to analyse factors associated with agreement. Results: From 2003 to 2014, out of a total of 1,952 VAs, 80% of respondents reported the HIV status of the deceased. In 2013–2014, this figure was 99%. Of those with an HIV status known to the study, there was 89% agreement on HIV status between the VA and pre-mortem data, higher for HIV-negative people (92% than HIV-positive people (83%. There was 84% agreement on whether the deceased had started ART, and 72% of ART initiation dates matched within 1 year. Conclusions: In this population, HIV/ART information was often disclosed during a VA and matched well with other data sources. Reported HIV/ART status appears to be a reliable source of information to help classification of cause of death.

  13. Enucleation of a large true cyst in the head of pancreas instead of Whipple procedure in an 8-year old boy: a case report

    OpenAIRE

    Ostadian N; Mirrokni SM; Noorzadeh M

    2011-01-01

    "nBackground: Simple cysts of pancreas are smaller than complex ones and are more likely to be located at the distal tail of the pancreas. Simple cysts are often asymptomatic and can be managed conservatively by observation. There seems to be few clinical trials to suggest the best treatments method for large symptomatic cysts of pancreas located at the head of the organ."n "nCase presentation: In this report, we describe an eight-year old boy with a large symptomatic true cyst...

  14. One-stage laparoscopic resection for a large gastric gastrointestinal stromal tumor and synchronous liver metastases following preoperative imatinib therapy: A case report.

    Science.gov (United States)

    Cao, Feng; Li, Jia; Li, Ang; Fang, Yu; Li, Fei

    2013-04-01

    Laparoscopic partial gastrectomy without lymph node dissection has been accepted worldwide for the treatment of small gastric gastrointestinal stromal tumors (GISTs). However, the role of laparoscopic surgery in the treatment of large gastric GISTs remains under debate due to the risk of tumor spillage or rupture of the tumor capsule leading to peritoneal seeding. To the best of our knowledge, one-stage laparoscopic resection for a large gastric GIST and synchronous liver metastases following preoperative imatinib therapy has not been previously reported. Here, we present our initial experience of this method of treatment.

  15. Prognostic significance of centromere 17 copy number gain in breast cancer depends on breast cancer subtype.

    Science.gov (United States)

    Lee, Kyuongyul; Jang, Min Hye; Chung, Yul Ri; Lee, Yangkyu; Kang, Eunyoung; Kim, Sung-Won; Kim, Yu Jung; Kim, Jee Hyun; Kim, In Ah; Park, So Yeon

    2017-03-01

    Increased copy number of chromosome enumeration probe (CEP) targeting centromere 17 is frequently encountered during HER2 in situ hybridization (ISH) in breast cancer. The aim of this study was to clarify the clinicopathologic significance of CEP17 copy number gain in a relatively large series of breast cancer patients. We analyzed 945 cases of invasive breast cancers whose HER2 fluorescence ISH reports were available from 2004 to 2011 at a single institution and evaluated the association of CEP17 copy number gain with clinicopathologic features of tumors and patient survival. We detected 186 (19.7%) cases of CEP17 copy number gain (CEP17≥3.0) among 945 invasive breast cancers. In survival analysis, CEP17 copy number gain was not associated with disease-free survival of the patients in the whole group. Nonetheless, it was found to be an independent adverse prognostic factor in the HER2-negative group but not in the HER2-positive group. In further subgroup analyses, CEP17 copy number gain was revealed as an independent poor prognostic factor in HER2-negative and hormone receptor-positive breast cancers, and it was associated with aggressive histologic variables including high T stage, high histologic grade, lymphovascular invasion, p53 overexpression, and high Ki-67 proliferative index. In conclusion, we found that elevated CEP17 count can serve as a prognostic marker in luminal/HER2-negative subtype of invasive breast cancer. We advocate the use of the dual-colored fluorescence ISH using CEP17 rather than the single-colored one because it gives additional valuable information on CEP17 copy number alterations. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Studies on pressure-gain combustion engines

    Science.gov (United States)

    Matsutomi, Yu

    Various aspects of the pressure-gain combustion engine are investigated analytically and experimentally in the current study. A lumped parameter model is developed to characterize the operation of a valveless pulse detonation engine. The model identified the function of flame quenching process through gas dynamic process. By adjusting fuel manifold pressure and geometries, the duration of the air buffer can be effectively varied. The parametric study with the lumped parameter model has shown that engine frequency of up to approximately 15 Hz is attainable. However, requirements for upstream air pressure increases significantly with higher engine frequency. The higher pressure requirement indicates pressure loss in the system and lower overall engine performance. The loss of performance due to the pressure loss is a critical issue for the integrated pressure-gain combustors. Two types of transitional methods are examined using entropy-based models. An accumulator based transition has obvious loss due to sudden area expansion, but it can be minimized by utilizing the gas dynamics in the combustion tube. An ejector type transition has potential to achieve performance beyond the limit specified by a single flow path Humphrey cycle. The performance of an ejector was discussed in terms of apparent entropy and mixed flow entropy. Through an ideal ejector, the apparent part of entropy increases due to the reduction in flow unsteadiness, but entropy of the mixed flow remains constant. The method is applied to a CFD simulation with a simple manifold for qualitative evaluation. The operation of the wave rotor constant volume combustion rig is experimentally examined. The rig has shown versatility of operation for wide range of conditions. Large pressure rise in the rotor channel and in a section of the exhaust duct are observed even with relatively large leakage gaps on the rotor. The simplified analysis indicated that inconsistent combustion is likely due to insufficient

  17. Does the use of structured reporting improve usability? A comparative evaluation of the usability of two approaches for findings reporting in a large-scale telecardiology context.

    Science.gov (United States)

    Lacerda, Thaisa Cardoso; von Wangenheim, Christiane Gresse; von Wangenheim, Aldo; Giuliano, Isabela

    2014-12-01

    One of the main reasons that leads to a low adoption rate of telemedicine systems is poor usability. An aspect that influences usability during the reporting of findings is the input mode, e.g., if a free-text (FT) or a structured report (SR) interface is employed. The objective of our study is to compare the usability of FT and ST telemedicine systems, specifically in terms of user satisfaction, efficiency and general usability. We comparatively evaluate the usability of these two input modes in a telecardiology system for issuing electrocardiography reports in the context of a statewide telemedicine system in Brazil with more than 350.000 performed tele-electrocardiography examinations. We adopted a multiple method research strategy, applying three different kinds of usability evaluations: user satisfaction was evaluated through interviews with seven medical professionals using the System Usability Scale (SUS) questionnaire and specific questions related to adequacy and user experience. Efficiency was evaluated by estimating execution time using the Keystroke-Level Model (KLM). General usability was assessed based on the conformity of the systems to a set of e-health specific usability heuristics. The results of this comparison provide a first indication that a structured report (SR) input mode for such a system is more satisfactory and efficient with a larger conformity to usability heuristics than free-text (FT) input. User satisfaction using the SUS questionnaire has been scored in average with 58.8 and 77.5 points for the FT and SR system, respectively, which means that the SR system was rated 18.65 points higher than the FT system. In terms of efficiency, the completion of a findings report using the SR mode is estimated to take 8.5s, 3.74 times faster than using the FT system (31.8s). The SR system also demonstrated less violations to usability heuristics (8 points) in comparison to 14 points observed in the FT system. These results provide a first

  18. Overlapping 16p13.11 deletion and gain of copies variations associated with childhood onset psychosis include genes with mechanistic implications for autism associated pathways: Two case reports.

    Science.gov (United States)

    Brownstein, Catherine A; Kleiman, Robin J; Engle, Elizabeth C; Towne, Meghan C; D'Angelo, Eugene J; Yu, Timothy W; Beggs, Alan H; Picker, Jonathan; Fogler, Jason M; Carroll, Devon; Schmitt, Rachel C O; Wolff, Robert R; Shen, Yiping; Lip, Va; Bilguvar, Kaya; Kim, April; Tembulkar, Sahil; O'Donnell, Kyle; Gonzalez-Heydrich, Joseph

    2016-05-01

    Copy number variability at 16p13.11 has been associated with intellectual disability, autism, schizophrenia, epilepsy, and attention-deficit hyperactivity disorder. Adolescent/adult- onset psychosis has been reported in a subset of these cases. Here, we report on two children with CNVs in 16p13.11 that developed psychosis before the age of 7. The genotype and neuropsychiatric abnormalities of these patients highlight several overlapping genes that have possible mechanistic relevance to pathways previously implicated in Autism Spectrum Disorders, including the mTOR signaling and the ubiquitin-proteasome cascades. A careful screening of the 16p13.11 region is warranted in patients with childhood onset psychosis. © 2016 Wiley Periodicals, Inc.

  19. Fetal Programming of Obesity: Maternal Obesity and Excessive Weight Gain

    Directory of Open Access Journals (Sweden)

    Seray Kabaran

    2014-10-01

    Full Text Available The prevalence of obesity is an increasing health problem throughout the world. Maternal pre-pregnancy weight, maternal nutrition and maternal weight gain are among the factors that can cause childhood obesity. Both maternal obesity and excessive weight gain increase the risks of excessive fetal weight gain and high birth weight. Rapid weight gain during fetal period leads to changes in the newborn body composition. Specifically, the increase in body fat ratio in the early periods is associated with an increased risk of obesity in the later periods. It was reported that over-nutrition during fetal period could cause excessive food intake during postpartum period as a result of metabolic programming. By influencing the fetal metabolism and tissue development, maternal obesity and excessive weight gain change the amounts of nutrients and metabolites that pass to the fetus, thus causing excessive fetal weight gain which in turn increases the risk of obesity. Fetal over-nutrition and excessive weight gain cause permanent metabolic and physiologic changes in developing organs. While mechanisms that affect these organs are not fully understood, it is thought that the changes may occur as a result of the changes in fetal energy metabolism, appetite control, neuroendocrine functions, adipose tissue mass, epigenetic mechanisms and gene expression. In this review article, the effects of maternal body weight and weight gain on fetal development, newborn birth weight and risk of obesity were evaluated, and additionally potential mechanisms that can explain the effects of fetal over-nutrition on the risk of obesity were investigated [TAF Prev Med Bull 2014; 13(5.000: 427-434

  20. A rare case report of a primary large-cell neuroendocrine carcinoma of the breast with coexisting Paget disease.

    Science.gov (United States)

    Psoma, Elizabeth; Nikolaidou, Olga; Stavrogianni, Thomai; Mavromati, Areti; Lytras, Konstantinos; Xirou, Persefoni; Koumbanaki, Melanie; Panagiotopoulou, Dimitra

    2012-01-01

    Neuroendocrine carcinomas are malignancies deriving from neuroendocrine cells existing in various sites of the body, most commonly in the lungs and gastrointestinal tract. Primary neuroendocrine carcinomas of the breast are extremely rare, and their diagnosis is confirmed by positive neuroendocrine markers. We describe a case of a 46-year-old woman with a palpable mass in her left breast for the previous 3 months. The tumor was resected and a primary large-cell neuroendocrine tumor of the breast was confirmed by histopathologic examination. Paget disease of the nipple was noted as well.

  1. Evaluation of airborne geophysical surveys for large-scale mapping of contaminated mine pools: draft final report

    Energy Technology Data Exchange (ETDEWEB)

    Hammack, R. W. [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United States). Geosciences Div.

    2006-12-28

    Decades of underground coal mining has left about 5,000 square miles of abandoned mine workings that are rapidly filling with water. The water quality of mine pools is often poor; environmental regulatory agencies are concerned because water from mine pools could contaminate diminishing surface and groundwater supplies. Mine pools are also a threat to the safety of current mining operations. Conversely, mine pools are a large, untapped water resource that, with treatment, could be used for a variety of industrial purposes. Others have proposed using mine pools in conjunction with heat pumps as a source of heating and cooling for large industrial facilities. The management or use of mine pool water requires accurate maps of mine pools. West Virginia University has predicted the likely location and volume of mine pools in the Pittsburgh Coalbed using existing mine maps, structure contour maps, and measured mine pool elevations. Unfortunately, mine maps only reflect conditions at the time of mining, are not available for all mines, and do not always denote the maximum extent of mining. Since 1999, the National Energy Technology Laboratory (NETL) has been evaluating helicopter-borne, electromagnetic sensing technologies for the detection and mapping of mine pools. Frequency domain electromagnetic sensors are able to detect shallow mine pools (depth < 50 m) if there is sufficient contrast between the conductance of the mine pool and the conductance of the overburden. The mine pools (conductors) most confidently detected by this technology are overlain by thick, resistive sandstone layers. In 2003, a helicopter time domain electromagnetic sensor was applied to mined areas in southwestern Virginia in an attempt to increase the depth of mine pool detection. This study failed because the mine pool targets were thin and not very conductive. Also, large areas of the surveys were degraded or made unusable by excessive amounts of cultural electromagnetic noise that obscured the

  2. Large scale solubilization of coal and bioconversion to utilizable energy. Quarterly report, October 1--December 31, 1996

    Energy Technology Data Exchange (ETDEWEB)

    Mishra, N.C.

    1996-12-22

    In order to develop a system for a large scale coal solubilization and its bioconversion to utilizable fuel, the author plans to clone the genes encoding Neurospora protein that facilitate depolymerization of coal. He also plans to use desulfurizing bacteria to remove the sulfur in situ and use other microorganisms to convert biosolubilized coal into utilizable energy following an approach utilizing several microorganisms. In addition the product of coal solubilized by fungus will be characterized to determine their chemical nature and the mechanism of reaction catalyzed by fungal product during in vivo and in vitro solubilization by the fungus or purified fungal protein.

  3. Large scale solubilization of coal and bioconversion to utilizable energy. Fifth quarterly technical report, January 1, 1995--March 31, 1995

    Energy Technology Data Exchange (ETDEWEB)

    Mishra, N.C.

    1995-12-01

    In order to develop a system for a large scale coal solubilization and its bioconversion to utilizable fuel, we plan to clone the genes encoding Neurospora protein that facilitate depolymerization of coal. We also plan to use desulfurizing bacteria to remove the sulfur in situ and use other microorganisms to convert biosolubilized coal into utilizable energy following an approach utilizing several microorganisms. In addition the product of coal solubilized by fungus will be characterized to determine their chemical nature and the mechanism of reaction catalyzed by fungal product during in vivo and in vitro solubilization by the fungus or purified fungal protein.

  4. Breastfeeding gains popularity in Honduras.

    Science.gov (United States)

    Townsend, S

    1992-10-01

    In 1982, a breast feeding support program (PROALMA) first operated in 3 large public hospitals and a large health center in Tegucigalpa and San Pedro Sula, Honduras. It trained health workers about the benefits of breast feeding and lactation management and developed hospital breast feeding policies and practices, e.g., creation of a milk bank for premature newborns. It even convinced hospitals to stop free distribution of infant formula and bottles. In fact, annual expenditures for infant formula at the Social Security Hospital in San Pedro Sula fell from US$ 40,000 to 6000 in 1 year and to 0 by 1990. Hospital practices which were not conducive to breast feeding included separation of newborns from mothers and giving newborns sugar water as their first food. In fact, 69% of mothers at Tegucigalpa hospitals said hospital staff gave their newborns breast milk substitutes within 24 hours of birth. The program began a rooming-in system which made it easier for mothers to initiate early, frequent, and on-demand breast feeding. PROALMA staff were in the maternity wards daily to provide breast feeding counseling. At the end of 3 years, 98% of women delivering at Tegucigalpa hospitals breast fed their infants. The project eventually expanded to hospitals nationwide. Between 1981 and 1988, breast feeding rose from 80% to 93% in cities and from 95% to 98% in rural areas. Further, the median duration of breast feeding increased from 4 months to 10 months (1982-1987) in cities. Yet, just 6% of mothers exclusively breast fed their 3-4 month old infants in 1987. In addition, only 28% exclusively breast fed before introducing the bottle. Staff attitude improved as evidenced by an increase in the percentage of workers promoting breast feeding at birth (37-86% during 1982-1986). PROALMA concluded that increased efforts to promote exclusive breast feeding are needed.

  5. A RARE CASE OF LARGE VESICAL CALCULUS AROUND A PROL ONGED DOUBLE J STENT: A CASE REPORT

    Directory of Open Access Journals (Sweden)

    Sunil Kr.

    2013-04-01

    Full Text Available ABSTRACT: D/J stents constitute an important armamentarium in the hands of an urosurgeon. During short term placement (4-12 weeks, they may c ause flank pain and irritative voiding symptoms, referred to as “stent syndrome.” Complicati ons occur in patients with long term placement of stents who do not come for follow-up - t he forgotten stent. We report a female case with something coming out from external meatus since 2 days with past history of open surgery for right PUJ obstruction with D/J stent in sertion 9 years ago. X-ray KUB & USG abdomen shows a huge vesical calculus around remain ing of the D/J stent. We operated the case with good outcome. This type of rare presentation o f D/J stent motivate us to report this case

  6. Self-reported household impacts of large-scale chemical contamination of the public water supply, Charleston, West Virginia, USA.

    Directory of Open Access Journals (Sweden)

    Charles P Schade

    Full Text Available A January 2014 industrial accident contaminated the public water supply of approximately 300,000 homes in and near Charleston, West Virginia (USA with low levels of a strongly-smelling substance consisting principally of 4-methylcyclohexane methanol (MCHM. The ensuing state of emergency closed schools and businesses. Hundreds of people sought medical care for symptoms they related to the incident. We surveyed 498 households by telephone to assess the episode's health and economic impact as well as public perception of risk communication by responsible officials. Thirty two percent of households (159/498 reported someone with illness believed to be related to the chemical spill, chiefly dermatological or gastrointestinal symptoms. Respondents experienced more frequent symptoms of psychological distress during and within 30 days of the emergency than 90 days later. Sixty-seven respondent households (13% had someone miss work because of the crisis, missing a median of 3 days of work. Of 443 households reporting extra expenses due to the crisis, 46% spent less than $100, while 10% spent over $500 (estimated average about $206. More than 80% (401/485 households learned of the spill the same day it occurred. More than 2/3 of households complied fully with "do not use" orders that were issued; only 8% reported drinking water against advice. Household assessments of official communications varied by source, with local officials receiving an average "B" rating, whereas some federal and water company communication received a "D" grade. More than 90% of households obtained safe water from distribution centers or stores during the emergency. We conclude that the spill had major economic impact with substantial numbers of individuals reporting incident-related illnesses and psychological distress. Authorities were successful supplying emergency drinking water, but less so with risk communication.

  7. Association Testing of Previously Reported Variants in a Large Case-Control Meta-analysis of Diabetic Nephropathy

    Science.gov (United States)

    Williams, Winfred W.; Salem, Rany M.; McKnight, Amy Jayne; Sandholm, Niina; Forsblom, Carol; Taylor, Andrew; Guiducci, Candace; McAteer, Jarred B.; McKay, Gareth J.; Isakova, Tamara; Brennan, Eoin P.; Sadlier, Denise M.; Palmer, Cameron; Söderlund, Jenny; Fagerholm, Emma; Harjutsalo, Valma; Lithovius, Raija; Gordin, Daniel; Hietala, Kustaa; Kytö, Janne; Parkkonen, Maija; Rosengård-Bärlund, Milla; Thorn, Lena; Syreeni, Anna; Tolonen, Nina; Saraheimo, Markku; Wadén, Johan; Pitkäniemi, Janne; Sarti, Cinzia; Tuomilehto, Jaakko; Tryggvason, Karl; Österholm, Anne-May; He, Bing; Bain, Steve; Martin, Finian; Godson, Catherine; Hirschhorn, Joel N.; Maxwell, Alexander P.; Groop, Per-Henrik; Florez, Jose C.

    2012-01-01

    We formed the GEnetics of Nephropathy–an International Effort (GENIE) consortium to examine previously reported genetic associations with diabetic nephropathy (DN) in type 1 diabetes. GENIE consists of 6,366 similarly ascertained participants of European ancestry with type 1 diabetes, with and without DN, from the All Ireland-Warren 3-Genetics of Kidneys in Diabetes U.K. and Republic of Ireland (U.K.-R.O.I.) collection and the Finnish Diabetic Nephropathy Study (FinnDiane), combined with reanalyzed data from the Genetics of Kidneys in Diabetes U.S. Study (U.S. GoKinD). We found little evidence for the association of the EPO promoter polymorphism, rs161740, with the combined phenotype of proliferative retinopathy and end-stage renal disease in U.K.-R.O.I. (odds ratio [OR] 1.14, P = 0.19) or FinnDiane (OR 1.06, P = 0.60). However, a fixed-effects meta-analysis that included the previously reported cohorts retained a genome-wide significant association with that phenotype (OR 1.31, P = 2 × 10−9). An expanded investigation of the ELMO1 locus and genetic regions reported to be associated with DN in the U.S. GoKinD yielded only nominal statistical significance for these loci. Finally, top candidates identified in a recent meta-analysis failed to reach genome-wide significance. In conclusion, we were unable to replicate most of the previously reported genetic associations for DN, and significance for the EPO promoter association was attenuated. PMID:22721967

  8. Self-reported household impacts of large-scale chemical contamination of the public water supply, Charleston, West Virginia, USA.

    Science.gov (United States)

    Schade, Charles P; Wright, Nasandra; Gupta, Rahul; Latif, David A; Jha, Ayan; Robinson, John

    2015-01-01

    A January 2014 industrial accident contaminated the public water supply of approximately 300,000 homes in and near Charleston, West Virginia (USA) with low levels of a strongly-smelling substance consisting principally of 4-methylcyclohexane methanol (MCHM). The ensuing state of emergency closed schools and businesses. Hundreds of people sought medical care for symptoms they related to the incident. We surveyed 498 households by telephone to assess the episode's health and economic impact as well as public perception of risk communication by responsible officials. Thirty two percent of households (159/498) reported someone with illness believed to be related to the chemical spill, chiefly dermatological or gastrointestinal symptoms. Respondents experienced more frequent symptoms of psychological distress during and within 30 days of the emergency than 90 days later. Sixty-seven respondent households (13%) had someone miss work because of the crisis, missing a median of 3 days of work. Of 443 households reporting extra expenses due to the crisis, 46% spent less than $100, while 10% spent over $500 (estimated average about $206). More than 80% (401/485) households learned of the spill the same day it occurred. More than 2/3 of households complied fully with "do not use" orders that were issued; only 8% reported drinking water against advice. Household assessments of official communications varied by source, with local officials receiving an average "B" rating, whereas some federal and water company communication received a "D" grade. More than 90% of households obtained safe water from distribution centers or stores during the emergency. We conclude that the spill had major economic impact with substantial numbers of individuals reporting incident-related illnesses and psychological distress. Authorities were successful supplying emergency drinking water, but less so with risk communication.

  9. ROBOT-ASSISTED LAPAROSCOPIC VESICULECTOMY FOR LARGE SEMINAL VESICLE CYSTOADENOMA: A CASE REPORT AND REVIEW OF THE LITERATURE

    OpenAIRE

    Riccardo Campi (a cura di); Maria Rosaria Raspollini; Agostino Tuccio; Andrea Mari; Giampaolo Siena; Sergio Serni; Andrea Minervini,; Alberto Lapini

    2015-01-01

    Case Report: A 47-year-old patient was referred to our centre for gross hematuria, mild dysuria and other lower urinary tract symptoms (LUTS). Past medical history was unremarkable and no co-morbidities were present. Digital rectal examination (DRE) revealed, cranially to the prostate, a tense-elastic mass with undefined upper and lateral boundaries. Prostate-specific antigen (PSA) level was 1.7 ng/ml. Physical examination and laboratory tests were otherwise normal. Trans-ab...

  10. Influences of finite gain bandwidth on pulse propagation in parabolic fiber amplifiers with distributed gain profiles

    Institute of Scientific and Technical Information of China (English)

    Zhao Jia-Sheng; Li Pan; Chen Xiao-Dong; Feng Su-Juan; Mao Qing-He

    2012-01-01

    The evolutions of the pulses propagating in decreasing and increasing gain distributed fiber amplifiers with finite gain bandwidths are investigated by simulations with the nonlinear Schrodinger equation.The results show that the parabolic pulse propagations in both the decreasing and the increasing gain amplifiers are restricted by the finite gain bandwidth.For a given input pulse,by choosing a small initial gain coefficient and gain variation rate,the whole gain for the pulse amplification limited by the gain bandwidth may be higher,which is helpful for the enhancement of the output linearly chirped pulse energy.Compared to the decreasing gain distributed fiber amplifier,the increasing gain distributed amplifier may be more conducive to suppress the pulse spectral broadening and increase the critical amplifier length for achieving a larger output linearly chirped pulse energy.

  11. Correction of a Forefoot Deformity Caused by a Large, Solitary Metatarsal Osteochondroma in an Adolescent: A Case Report.

    Science.gov (United States)

    Patil, Sampat Dumbre; Patil, Vaishali Dumbre; Khan, Ashraf; Khanore, Charudatta

    2016-01-01

    Solitary osteochondroma is the most common bone tumor, accounting for 20% to 50% of all benign bony tumors. Osteochondromas are usually found on the metaphysis of the long bones near the physis; the bones of the foot are less commonly involved. We describe a 13-year-old female with a large osteochondroma arising from the fourth metatarsal. Pressure from the tumor on the adjacent metatarsals had deformed her forefoot, creating cosmetic and functional problems. The second and third toes were deviated laterally at the metatarsophalangeal joint, and the fourth and fifth toes were deviated medially. In addition, the fourth and fifth toes were flexed at the proximal interphalangeal joint. We excised the osteochondroma and stabilized the metatarsophalangeal joints. After 3 years, the cosmetic and functional results were satisfactory. The subluxation at the metatarsophalangeal joints had resolved without treatment. Her Revised Foot Function Index score had improved from 141 preoperatively to 95 postoperatively, and her Manchester-Oxford Foot Questionnaire score had improved from 25 to 0. This case is a rare example of a large metatarsal osteochondroma in a growing child in which pressure from the tumor caused secondary forefoot deformities. The management of this case also shows the potential for the forefoot to remodel itself during adolescence, after the tumor has been resected and the joints stabilized.

  12. Consultancy on Large-Scale Submerged Aerobic Cultivation Process Design - Final Technical Report: February 1, 2016 -- June 30, 2016

    Energy Technology Data Exchange (ETDEWEB)

    Crater, Jason [Gemomatica, Inc., San Diego, CA (United States); Galleher, Connor [Gemomatica, Inc., San Diego, CA (United States); Lievense, Jeff [Gemomatica, Inc., San Diego, CA (United States)

    2017-05-12

    NREL is developing an advanced aerobic bubble column model using Aspen Custom Modeler (ACM). The objective of this work is to integrate the new fermentor model with existing techno-economic models in Aspen Plus and Excel to establish a new methodology for guiding process design. To assist this effort, NREL has contracted Genomatica to critique and make recommendations for improving NREL's bioreactor model and large scale aerobic bioreactor design for biologically producing lipids at commercial scale. Genomatica has highlighted a few areas for improving the functionality and effectiveness of the model. Genomatica recommends using a compartment model approach with an integrated black-box kinetic model of the production microbe. We also suggest including calculations for stirred tank reactors to extend the models functionality and adaptability for future process designs. Genomatica also suggests making several modifications to NREL's large-scale lipid production process design. The recommended process modifications are based on Genomatica's internal techno-economic assessment experience and are focused primarily on minimizing capital and operating costs. These recommendations include selecting/engineering a thermotolerant yeast strain with lipid excretion; using bubble column fermentors; increasing the size of production fermentors; reducing the number of vessels; employing semi-continuous operation; and recycling cell mass.

  13. Optimization of Scatterer Concentration in High-Gain Scattering Media

    Institute of Scientific and Technical Information of China (English)

    ZHU Jiu-Gao; ZHU He-Yuan; SUN Die-Chi; DU Ge-Guo; LI Fu-Ming

    2001-01-01

    We report the scatterer concentration-dependent behaviour of laser action in high-gain scattering media. Amodified model of a random laser is proposed to explain the experimental results in good agreement. We mayuse this modified model to design and optimize the random laser system. A further detailed model is needed toquantitatively analyse the far-field distribution of random laser action.

  14. Advanced Large Scale Cross Domain Temporal Topic Modeling Algorithms to Infer the Influence of Recent Research on IPCC Assessment Reports

    Science.gov (United States)

    Sleeman, J.; Halem, M.; Finin, T.; Cane, M. A.

    2016-12-01

    Approximately every five years dating back to 1989, thousands of climate scientists, research centers and government labs volunteer to prepare comprehensive Assessment Reports for the Intergovernmental Panel on Climate Change. These are highly curated reports distributed to 200 nation policy makers. There have been five IPCC Assessment Reports to date, the latest leading to a Paris Agreement in Dec. 2016 signed thus far by 172 nations to limit the amount of global Greenhouse gases emitted to producing no more than a 20 C warming of the atmosphere. These reports are a living evolving big data collection tracing 30 years of climate science research, observations, and model scenario intercomparisons. They contain more than 200,000 citations over a 30 year period that trace the evolution of the physical basis of climate science, the observed and predicted impact, risk and adaptation to increased greenhouse gases and mitigation approaches, pathways, policies for climate change. Document-topic and topic-term probability distributions are built from the vocabularies of the respective assessment report chapters and citations. Using Microsoft Bing, we retrieve 150,000 citations referenced across chapters and convert those citations to text. Using a word n-gram model based on a heterogeneous set of climate change terminology, lemmatization, noise filtering and stopword elimination, we calculate word frequencies for chapters and citations. Temporal document sets are built based on the assessment period. In addition to topic modeling, we employ cross domain correlation measures. Using the Jensen-Shannon divergence and Pearson correlation we build correlation matrices for chapter and citations topics. The shared vocabulary acts as the bridge between domains resulting in chapter-citation point pairs in space. Pairs are established based on a document-topic probability distribution. Each chapter and citation is associated with a vector of topics and based on the n most probable

  15. Gain Characteristics of Fiber Optical Parametric Amplifier

    Institute of Scientific and Technical Information of China (English)

    高明义; 姜淳; 胡卫生

    2004-01-01

    The theory model of fiber optical parametric amplifier (FOPA) was introduced, which is based on optical nonlinear effect. And then numerical simulation was done to analyze and discuss the gain spectral characteristics of one-pump and two-pump FOPA. The results show that for one-pump FOPA, when pump wavelength is near to fiber zero-dispersion wavelength(ZDW), the gain flatness is better, and with the increase of the pump power, fiber length and its nonlinear coefficient, the gain value will increase while the gain bandwidth will become narrow. For two-pump FOPA, when the pump central wavelength is near to fiber ZDW, the gain flatness is better. Moreover, by decreasing the space of two pumps wavelength, the gain flatness can be improved. Finally, some problems existing in FOPA were addressed.

  16. Optical antenna gain. I - Transmitting antennas

    Science.gov (United States)

    Klein, B. J.; Degnan, J. J.

    1974-01-01

    The gain of centrally obscured optical transmitting antennas is analyzed in detail. The calculations, resulting in near- and far-field antenna gain patterns, assume a circular antenna illuminated by a laser operating in the TEM-00 mode. A simple polynomial equation is derived for matching the incident source distribution to a general antenna configuration for maximum on-axis gain. An interpretation of the resultant gain curves allows a number of auxiliary design curves to be drawn that display the losses in antenna gain due to pointing errors and the cone angle of the beam in the far field as a function of antenna aperture size and its central obscuration. The results are presented in a series of graphs that allow the rapid and accurate evaluation of the antenna gain which may then be substituted into the conventional range equation.

  17. Optical antenna gain. 1: transmitting antennas.

    Science.gov (United States)

    Klein, B J; Degnan, J J

    1974-09-01

    The gain of centrally obscured optical transmitting antennas is analyzed in detail. The calculations, resulting in near- and far-field antenna gain patterns, assume a circular antenna illuminated by a laser operating in the TEM(00) mode. A simple polynomial equation is derived for matching the incident source distribution to a general antenna configuration for maximum on-axis gain. An interpretation of the resultant gain curves allows a number of auxiliary design curves to be drawn that display the losses in antenna gain due to pointing errors and the cone angle of the beam in the far field as a function of antenna aperture size and its central obscuration. The results are presented in a series of graphs that allow the rapid and accurate evaluation of the antenna gain which may then be substituted into the conventional range equation.

  18. Microchannel plate modal gain variations with temperature

    Science.gov (United States)

    Slater, David C.; Timothy, J. G.

    1993-01-01

    Measurements of the modal gain of two high-gain curved-channel microchannel plates (MCPs) at various operating temperatures are presented. Both MCPs were fabricated from the Long Life glass with 12-micron diam channels on 15-micron centers. The modal gain was found to decrease with increasing temperature at a rate of -0.1 percent C. This reduction of gain with temperature is attributed primarily to an axial temperature gradient along each MCP channel creating a nonuniform electric field within the channel that lowers the effective output gain. A lowering of the secondary electron yield resulting from increased phonon scattering of secondary electrons released within the walls of the MCP channels was assessed, but was found to have a negligible contribution to the drop in gain with temperature.

  19. Exploring sudden gains in behavioral activation therapy for Major Depressive Disorder.

    Science.gov (United States)

    Hunnicutt-Ferguson, Kallio; Hoxha, Denada; Gollan, Jackie

    2012-03-01

    Understanding the onset and course of sudden gains in treatment provides clinical information to the patient and clinician, and encourages clinicians to strive for these sudden clinical gains with their patients. This study characterizes the occurrence of sudden gains with Behavioral Activation (BA; Martell, Addis, & Jacobson, 2001), and the extent to which pre-treatment dysfunctional depressive thinking predicts sudden gains during treatment. We enrolled a sample of adults (n = 42) between ages 18-65 diagnosed with primary Major Depressive Disorder. All participants completed a 16-week course of BA, with clinical and self-report assessments at pre-, mid- and post-treatment. Results indicated that sudden gain and non-sudden gain participants showed differential improvement across treatment. No significant effects emerged for the dysfunctional cognitive style as a predictor of sudden gain status. Sudden gains may result from interaction of non-specific factors with the BA techniques implemented during early phases of therapy.

  20. Control of Spacecraft Formation with Disturbance Rejection and Exponential Gains

    Directory of Open Access Journals (Sweden)

    R. Schlanbusch

    2013-01-01

    Full Text Available We address the problem of state feedback translational motion control of a spacecraft formation through a modified sliding surface controller using variable gains and I^2 action for disturbance rejection. The exponential varying gains ensure faster convergence of the state trajectories during attitude maneuver while keeping the gains small (and the system less stiff for station keeping. Integral action is introduced for rejection of disturbances with a constant nonzero mean such as aerodynamic drag. A direct consequence is a drop in energy consumption when affected by sensor noise and a decrease in size of the error states residual when operating close to the equilibrium point. A large number of simulation results are presented to show the control performance.

  1. Controlling noise in plasmonic structures with gain

    Science.gov (United States)

    Vyshnevyy, A. A.; Fedyanin, D. Yu.

    2017-09-01

    Loss compensation by gain medium gives the possibility to exploit subwavelength confinement of light in plasmonic nanostructures and construct nanoscale plasmonic circuits. However, due to fundamentally unavoidable spontaneous emission from the gain medium, lossless waveguides suffer from strong photonic noise, which limits their practical applications. Here we demonstrate the possibility of significant decrease of the noise level while preserving physical dimensions of lossless plasmonic waveguides with gain. Our findings are aimed at extending the communication capabilities of on-chip plasmonic networks.

  2. Resection of large invasive pituitary adenomas with individualized approach under neuronavigator guidance:a report of 17 cases

    Directory of Open Access Journals (Sweden)

    Jing-min CHENG

    2011-05-01

    Full Text Available Objective To explore the operative method and therapeutic efficacy of surgical resection of large invasive pituitary adenomas with individualized approach under neuronavigator guidance.Methods Seventeen patients(10 males and 7 females,aged from 22 to 78 years with a mean of 39.2±9.2 years suffering from large invasive pituitary adenoma of higher than Hardy IV grade hospitalized from 2004 to 2009 were involved in the present study.All procedures were performed with the assistance of neuronavigator via individualized pterion approach,subfrontal extradural approach,trans-sphenoidal approach,or combined approach.The dispersedly invasive pituitary adenomas were resected under the guidance of neuronavigator by fully utilizing the natural anatomical cleavages.All the patients received follow-up CT scanning 3 days after operation,MRI scanning 1 to 3 months after operation,and clinical follow-up ranged from 6 to 72 months.The resection extent and outcome were assessed by imaging examination and clinical results.Results Total tumor removal was achieved in 15 cases,subtotal removal in 1 case,and extensive partial removal in 1 case.The visual impairment and headache were ameliorated in most cases,but in 1 patient they were worsened.Transient diabetes insipidus occurred in 8 cases,electrolyte disturbances were observed in 2 cases,leakage of cerebrospinal fluid appeared in 2 cases,hyposmia in 2 cases,visual impairment aggravated in 1 case,oculomotor nerve and abducens nerve paralysis on the operative side in 1 case,epidural hematoma in occipital and parietal regions in 1 case.No patient died during the follow-up period.Conclusions Individualized surgical approach designed according to the growth direction of tumor under neuronavigator guidance is helpful for the operators to identify the vessels and nerves in the operative field distinctly during the operation,thus the total removal rate is improved,safely of the operation to remove large invasive pituitary

  3. Self-similar erbium-doped fiber laser with large normal dispersion.

    Science.gov (United States)

    Liu, Hui; Liu, Zhanwei; Lamb, Erin S; Wise, Frank

    2014-02-15

    We report a large normal dispersion erbium-doped fiber laser with self-similar pulse evolution in the gain fiber. The cavity is stabilized by the local nonlinear attractor in the gain fiber through the use of a narrow filter. Experimental results are accounted for by numerical simulations. This laser produces 3.5 nJ pulses, which can be dechirped to 70 fs with an external grating pair.

  4. Self-similar erbium-doped fiber laser with large normal dispersion

    OpenAIRE

    Liu, Hui; Liu, Zhanwei; Lamb, Erin S.; Wise, Frank

    2014-01-01

    We report a large normal dispersion erbium-doped fiber laser with self-similar pulse evolution in the gain fiber. The cavity is stabilized by the local nonlinear attractor in the gain fiber through the use of a narrow filter. Experimental results are accounted for by numerical simulations. This laser produces 3.5 nJ pulses, which can be dechirped to 70 fs with an external grating pair.

  5. Unusually large complex odontoma in maxillary sinus associated with unerupted tooth. Report of case and review of literature.

    Science.gov (United States)

    Singer, Steven R; Mupparapu, Muralidhar; Milles, Maano; Rinaggio, Joseph; Pisano, Dominic; Quaranta, Patrick

    2007-01-01

    An unusual case of a large complex odontoma with an associated impacted tooth is presented. Odontomas are hamartomatous growths of enamel, dentin, cementum and pulp tissue. Although they are usually tooth-sized or smaller, occasionally, the complex variant can exhibit considerable growth, as was seen in the case presented here. It occupied most of the maxillary sinus and displaced the floor of the orbit and the medial and posterior walls of the left maxillary sinus. Panoramic radiographs, as well as axial and coronal CT studies, showed the extent of the lesion in various dimensions. A differential diagnosis of various calcifying tumors was formulated on the basis of these findings. The lesion was surgically excised, and histologic analysis confirmed the radiographic impression. Although odontomas of this magnitude are rare, this case demonstrates the value of imaging, radiographic histopathologic diagnosis and surgical treatment planning prior to any definitive treatment.

  6. Ovarian dysfunction and FMR1 alleles in a large Italian family with POF and FRAXA disorders: case report

    Directory of Open Access Journals (Sweden)

    D'Urso Michele

    2007-04-01

    Full Text Available Abstract Background The association between premature ovarian failure (POF and the FMR1 repeat number (41> CGGnFMR1 alleles. Case presentation We describe the coexistence in a large Italian kindred of Fragile X syndrome and familial POF in females with ovarian dysfunctions who carried normal or expanded FMR1 alleles. Genetic analysis of the FMR1 gene in over three generations of females revealed that six carried pre-mutated alleles (61–200, of which two were also affected by POF. However a young woman, who presented a severe ovarian failure with early onset, carried normal FMR1 alleles ( Conclusion Our case study represents a helpful observation and will provide familial cases with heterogeneous etiology that could be further studied when candidate genes in addition to the FMR1 premutation will be available.

  7. Final Report on DOE Project entitled Dynamic Optimized Advanced Scheduling of Bandwidth Demands for Large-Scale Science Applications

    Energy Technology Data Exchange (ETDEWEB)

    Ramamurthy, Byravamurthy [University of Nebraska-Lincoln

    2014-05-05

    In this project, developed scheduling frameworks for dynamic bandwidth demands for large-scale science applications. In particular, we developed scheduling algorithms for dynamic bandwidth demands in this project. Apart from theoretical approaches such as Integer Linear Programming, Tabu Search and Genetic Algorithm heuristics, we have utilized practical data from ESnet OSCARS project (from our DOE lab partners) to conduct realistic simulations of our approaches. We have disseminated our work through conference paper presentations and journal papers and a book chapter. In this project we addressed the problem of scheduling of lightpaths over optical wavelength division multiplexed (WDM) networks. We published several conference papers and journal papers on this topic. We also addressed the problems of joint allocation of computing, storage and networking resources in Grid/Cloud networks and proposed energy-efficient mechanisms for operatin optical WDM networks.

  8. REPAIR OF LARGE SKULL BASE DEFECT FOLLOWING EXCISION OF BASALOID SQUAMOUS CELL CARCINOMA OF MAXILLO - ETHMOID REGION : A CASE REPORT

    Directory of Open Access Journals (Sweden)

    Monoj Mukherjee

    2015-02-01

    Full Text Available AIM: To present a case of basaloid squamous cell carcinoma of maxillo - ethmoid region with intracranial extradural extention and its surgical management including repair of the skull base defect. MATERIAL : A 30 year female presented with progressive bilateral nasal obstruction, facial deformity for 5 years duration. She developed blindness in last 6 months. Recent CT s can showed large heterogeneous enhancing soft tissue mass in right maxillary sinus, nasal cavity and right ethmoid sinus invading the skull base . INTERVENTION : She underwent excision of the mass by modified weber ferguson incision and repair of skull base defect with temporalis muscle flap. Skin defect over the face and nose was repaired by median forehead flap. RESULT : There was total tumor clearance and no CSF leakage following surgery. CONCLUSION : Sinonasal malignancy with intracranial extradural extenti on is not a contraindication for successful surgical management. Resultant skull base defect can be repaired by a temporalis muscle flap to prevent CSF leak and intracranial infection

  9. Site Release Reports for C-Well Pipeline, UE-25 Large Rocks Test Site, and 29 GSF Test Pits

    Energy Technology Data Exchange (ETDEWEB)

    K.E. Rasmuson

    2002-04-02

    The U.S. Department of Energy has implemented a program to reclaim lands disturbed by site characterization at Yucca Mountain. Long term goals of the program are to re-establish processes on disturbed sites that will lead to self-sustaining plant communities. The Biological Opinion for Yucca Mountain Site Characterization Studies required that the U.S. Department of Energy develop a Reclamation Standards and Monitoring Plan to evaluate the success of reclamation efforts. According to the Reclamation Standards and Monitoring Plan, reclaimed sites will be monitored periodically, remediated if necessary, and eventually compared to an appropriate reference area to determine whether reclamation goals have been achieved and the site can be released from further monitoring. Plant cover, density, and species richness (success parameters) on reclaimed sites are compared to 60 percent of the values (success criteria) for the same parameters on the reference area. Small sites (less than 0.1 ha) are evaluated for release using qualitative methods while large sites (greater than 0.1 ha) are evaluated using quantitative methods. In the summer of 2000, 31 small sites reclaimed in 1993 and 1994 were evaluated for reclamation success and potential release from further monitoring. Plant density, cover, and species richness were estimated on the C-Well Pipeline, UE-25 Large Rocks test site, and 29 ground surface facility test pits. Evidence of erosion, reproduction and natural recruitment, exotic species abundance, and animal use (key attributes) also were recorded for each site and used in success evaluations. The C-Well Pipeline and ground surface facility test pits were located in a ''Larrea tridentata - Ephedra nevadensis'' vegetation association while the UE-25 Large Rocks test site was located in an area dominated by ''Coleogyne ramosissima and Ephedra nevadensis''. Reference areas in the same vegetation associations with similar slope

  10. Large scale solubilization of coal and bioconversion to utilizable energy. Technical progress report, January 1--March 31, 1996

    Energy Technology Data Exchange (ETDEWEB)

    Mishra, N.C.

    1996-05-01

    In order develop a system for a large scale coal solubilization and its bioconversion to utilizable fuel, the authors plan to clone the genes encoding Neurospora protein that facilitates depolymerization of coal. They also plan to use desulfurizing bacteria to remove the sulfur in situ and use other microorganisms to convert biosolubilized coal into utilizable energy following an approach utilizing several microorganisms. In addition the products of coal solubilized by fungus will be characterized to determine their chemical nature and the mechanism of reaction catalyzed by fungal product during in vivo and in vitro solubilization by the fungus or purified fungal protein. Results are presented for the cloning of genes for Neurospora CSA-protein.

  11. Enhanced Gain in Photonic Crystal Amplifiers

    DEFF Research Database (Denmark)

    Ek, Sara; Semenova, Elizaveta; Hansen, Per Lunnemann;

    2012-01-01

    study of a 1 QW photonic crystal amplifier. Net gain is achieved which enables laser oscillation in photonic crystal micro cavities. The ability to freely tailor the dispersion in a semiconductor optical amplifier makes it possible to raise the optical gain considerably over a certain bandwidth......We experimentally demonstrate enhanced gain in the slow-light regime of quantum well photonic crystal amplifiers. A strong gain enhancement is observed with the increase of the group refractive index, due to light slow-down. The slow light enhancement is shown in a amplified spontaneous emission...

  12. Asymptomatic perforation of large bowel and urinary bladder as a complication of ventriculoperitoneal shunt: Report of two cases

    Directory of Open Access Journals (Sweden)

    Mihajlović Miljan

    2012-01-01

    Full Text Available Introduction. Insertion of a ventriculoperitoneal (VP shunt, the method of choice in the treatment of hydrocephalus, is often followed by various mechanical and/or infective complications. We present two children with asymptomatic perforation of the large bowel and urinary bladder, relatively rare and potentially severe complications of this surgical procedure. Outline of Cases. In both patients a VP shunt was implanted in the first month after birth; in a boy due to congenital hydrocephalus and in a girl due to the consequences of intracranial haemorrhage. Immediately after surgery, as well as during the further course, in both children growth and development were optimal and without any signs of infection or VP shunt malfunction. In the boy at age 6 months and in the girl at age 4 years, without any signs of complications, mothers noted the prominence of the VP shunt tip from the anus in the first case and from the urethral orifice in the second one. The VP shunts were immediately changed, so that both complications were resolved without any consequences. Conclusion. Insertion of a VP shunt represents the most frequent method of choice of the surgical treat- ment of hydrocephalus, but also potentially a highly risky procedure followed by various complications about which parents should be informed when patients are children. Owing to adequate approach in the follow-up of children with implanted VP shunt, large bowel and urinary bladder perforation, examples of severe and potentially fatal complications of this surgical intervention, could be disclosed on time and adequately resolved.

  13. Exploring the relationship between safety culture and reported dispensing errors in a large sample of Swedish community pharmacies.

    Science.gov (United States)

    Nordén-Hägg, Annika; Kälvemark-Sporrong, Sofia; Lindblad, Åsa Kettis

    2012-08-13

    The potential for unsafe acts to result in harm to patients is constant risks to be managed in any health care delivery system including pharmacies. The number of reported errors is influenced by a various elements including safety culture. The aim of this study is to investigate a possible relationship between reported dispensing errors and safety culture, taking into account demographic and pharmacy variables, in Swedish community pharmacies. A cross-sectional study was performed, encompassing 546 (62.8%) of the 870 Swedish community pharmacies. All staff in the pharmacies on December 1st, 2007 were included in the study. To assess safety culture domains in the pharmacies, the Safety Attitudes Questionnaire (SAQ) was used. Numbers of dispensed prescription items as well as dispensing errors for each pharmacy across the first half year of 2008 were summarised. Intercorrelations among a number of variables including SAQ survey domains, general properties of the pharmacy, demographic characteristics, and dispensing errors were calculated. A negative binomial regression model was used to further examine the relationship between the variables and dispensing errors. The first analysis demonstrated a number of significant correlations between reported dispensing errors and the variables examined. Negative correlations were found with SAQ domains Teamwork Climate, Safety Climate, Job Satisfaction as well as mean age and response rates. Positive relationships were demonstrated with Stress Recognition (SAQ), number of employees, educational diversity, birth country diversity, education country diversity and number of dispensed prescription items. Variables displaying a significant relationship to errors in this analysis were included in the regression analysis. When controlling for demographic variables, only Stress Recognition, mean age, educational diversity and number of dispensed prescription items and employees, were still associated with dispensing errors. This study

  14. Sudden losses and sudden gains during a DBT-PTSD treatment for posttraumatic stress disorder following childhood sexual abuse

    Directory of Open Access Journals (Sweden)

    Antje Krüger

    2014-09-01

    Full Text Available Background: Exposure-based treatment approaches are first-line interventions for patients suffering from posttraumatic stress disorder (PTSD. However, the dissemination of exposure-based treatments for PTSD is challenging, as a large proportion of clinicians report being concerned about symptoms worsening as a result of this type of intervention and are therefore reluctant to offer it to patients with PTSD. However, there is only little empirical evidence to date on the pattern of symptom worsening during exposure-based treatment for PTSD. Objective: The goal of the present study was to explore the frequency of sudden losses and sudden gains in the course of an exposure-based treatment programme for female patients suffering from PTSD related to childhood sexual abuse who also show severe comorbidity. In addition, the relationship between sudden changes and treatment outcome was examined. Methods: Female participants (N=74 were randomised to either a 12-week residential DBT-PTSD programme or a treatment-as-usual wait list. The pattern of symptom change was assessed via weekly assessments using the Posttraumatic Diagnostic Scale (PDS. Sudden changes were computed as suggested by the literature on sudden gains. Results: During treatment, only one participant (3% experienced a sudden loss, whereas 25% of participants experienced sudden gains. In the waiting condition, 8% of the participants experienced sudden losses and 5% experienced sudden gains during the same time period. No symptom worsening was observed in response to exposure sessions. However, sudden gains occurred during exposure and non-exposure treatment weeks. Patients with sudden gains showed better treatment outcome in the post-treatment and follow-up assessments. Conclusions: Exposure-based treatment did not lead to PTSD symptom worsening in the study sample. Results show that sudden gains occur frequently during PTSD treatment and have a prognostic value for treatment outcome.

  15. Anaplastic lymphoma kinase positive large B-cell lymphoma: Literature review and report of an endoscopic fine needle aspiration case with tigroid backgrounds mimicking seminoma.

    Science.gov (United States)

    Sakr, Hany; Cruise, Michael; Chahal, Prabhleen; Cotta, Claudiu; Cook, James; Chalikonda, Sricharan; Rosenblatt, Steven; Hamadeh, Fatima; Al-Nourhji, Omar; Sturgis, Charles D

    2017-02-01

    Anaplastic lymphoma kinase-positive large B-cell lymphoma (ALK+ LBCL) is a rare distinct type of non-Hodgkin's lymphoma that arises in association with alterations of the ALK gene. This distinct disease entity is typically associated with an aggressive clinical course and appears in light microscopic preparations as a monomorphic population of large, immunoblast-like cells. In this report, we describe a case of ALK+ LBCL diagnosed by transgastric endoscopic ultrasound-guided fine needle aspiration (EUS FNA) of splenic hilar lymph nodes. Modified Giemsa stained direct smears from the FNA sample demonstrated large lesional cells with foamy cytoplasm and macronucleoli admixed with small lymphocytes in tigroid backgrounds, mimicking the cytologic appearance of seminoma. Ancillary immunohistochemical studies subsequently confirmed the diagnosis of ALK+ LBCL with the lesional cells being immunoreactive for CD138, VS38c, MUM1, ALK1, and lambda light chain. The cohesiveness of the cells, the cellular morphology, and the tigroid backgrounds were all pitfalls for accurate diagnosis of this rare specific type of lymphoid malignancy by cytology. To our knowledge this is the first case report detailing the diagnosis of ALK+ LBCL by EUS FNA and the first report describing a glycogen-rich tigroid background in direct FNA smears. Establishing a refined diagnosis in cases of this rare form of LBCL is necessary, as therapies targeting ALK may be of value in clinical management. Diagn. Cytopathol. 2017;45:148-155. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  16. Report on experience gained in the water treatment plant Hoyerswerda/Saxony. Optimization of the utilization of iron salts; Erfahrungsbericht von der Klaeranlage Hoyerswerda/Sachsen. Optimierung des Einsatzes von Eisensalzen

    Energy Technology Data Exchange (ETDEWEB)

    Metan, H.J. [Versorgungsbetriebe Hoyerswerda GmbH (Germany). Klaeranlage; Scheffer, W. [Kronos International Inc., GB Wasserchemie, Langenfeld (Germany)

    1997-11-01

    This article reports on the operation of a waste processing plant in Hoyerswerda, Germany. The operation could be optimized by using KRONOFLOC iron(II)-chloride solution. With this iron salt several processes are possible: elimination of hydrogen sulfides and phosphates, desulfurization of digester gas, conditioning of sewage sludge and filtration by flocculation. (SR) [Deutsch] Die Aufgabe `Betriebskosteneinsparung durch Optimierung des Einsatzes von Eisensalzen` konnte erfuellt werden. Nach einer ueberschlaegigen Kalkulation liegt die Kostenersparnis insgesamt bei mehreren Zehntausend-DM. Eine Gesamtkostenbilanz ist nur schwer abschaetzbar, die Ergebnisse sind jedoch auf andere Klaeranlagen dieser Groesse und Bauart uebertragbar. Nur ein Faellungs- und Flockungsmittel wurde in die vorhandene Verfahrenstechnik integriert. Vorteile durch den Einsatz der neuen Eisen-II-chlorid-Loesung KRONO-FLOC ergeben sich vor allem durch: - Universelle Einsetzbarkeit - ein guenstiges Preis-/Leistungsverhaeltnis - gute Verfuegbarkeit des Produktes - gleichbleibende Qualitaet, d.h. konstante Wirksubstanz - Betriebssicherheit auch im Winter bei ueber -20 C. - Hohen Reinheitsstandard, d.h. niedrige Schwermetallkonzentrationen. (orig.)

  17. High gain multigap avalanche detectors for Cerenkov ring imaging

    Energy Technology Data Exchange (ETDEWEB)

    Gilmore, R.S.; Lavender, W.M.; Leith, D.W.G.S.; Williams, S.H.

    1980-10-01

    We report on a continuing study of multigap parallel plate avalanche chambers, primarily as photoelectron detectors for use with Cerenkov ring imaging counters. By suitable control of the fields in successive gaps and by introducing screens to reduce photon feedback to the cathode the gain many be increased considerably. We have obtained gains in excess of 6 x 10/sup 7/ for photoelectrons with a good pulse height spectrum and expect to increase this further. We discuss the use of resistive anodes to give avalanche positions in two dimensions by charge division.

  18. Large Mucocele of the Appendix at Laparoscopy Presenting as an Adnexal Mass in a Postmenopausal Woman: A Case Report

    Directory of Open Access Journals (Sweden)

    Elvira Paladino

    2014-01-01

    Full Text Available A 79-year-old female was referred to our Gynecologic Department presenting with a pelvic magnetic resonance imaging (MRI, showing an adnexal mass, later confirmed at the pelvic examination. The patient’s routine laboratory tests were normal. A sonographic examination was performed with inconclusive results. Although the ultrasonography excluded the presence of vascularization and malignant degeneration, the adnexal localization appeared to be dubious. The laparoscopy and the subsequent histologic examination revealed the presence of a mucocele of the appendix. The following case report focuses the attention on a misdiagnosis of appendiceal mucocele. The misdiagnosis caused no negative impact on the treatment that in this case was adequate and successful.

  19. A large dumbbell glossopharyngeal schwannoma involving the vagus nerve: a case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Zhao Hongyu

    2008-10-01

    Full Text Available Abstract Introduction Schwannoma arising from the glossopharyngeal nerve is a rare intracranial tumor. Fewer than 40 cases have been reported. Accurate pre-operative diagnosis and optimal treatment are still difficult. Case presentation We present one case of schwannoma originating from the ninth cranial nerve with palsies of the trigeminal nerve, facial-acoustic nerve complex, and vagus nerve in addition to ninth nerve dysfunction. Magnetic resonance imaging showed tumors located in the cerebellopontine angle with extracranial extension via the jugular foramen, with evident enhancement on post-contrast scan. Surgical management single-staged with the help of gamma knife radiosurgery achieved total removal. Conclusion Glossopharyngeal schwannoma is devoid of clinical symptoms and neurological signs. High resolution magnetic resonance imaging may play a key role as an accurate diagnostic tool. A favorable option of approach and appropriate planning of surgical strategy should be the goal of operation for this benign tumor.

  20. A Large Hadron Electron Collider at CERN: Report on the Physics and Design Concepts for Machine and Detector

    CERN Document Server

    Abelleira Fernandez, J L; Akay, A N; Aksakal, H; Albacete, J L; Alekhin, S; Allport, P; Andreev, V; Appleby, R B; Arikan, E; Armesto, N; Azuelos, G; Bai, M; Barber, D; Bartels, J; Behnke, O; Behr, J; Belyaev, A S; Ben-Zvi, I; Bernard, N; Bertolucci, S; Bettoni, S; Biswal, S; Blumlein, J; Bottcher, H; Bogacz, A; Bracco, C; Brandt, G; Braun, H; Brodsky, S; Brüning, O; Bulyak, E; Buniatyan, A; Burkhardt, H; Cakir, I T; Cakir, O; Calaga, R; Cetinkaya, V; Ciapala, E; Ciftci, R; Ciftci, A K; Cole, B A; Collins, J C; Dadoun, O; Dainton, J; De Roeck, A; d'Enterria, D; Dudarev, A; Eide, A; Enberg, R; Eroglu, E; Eskola, K J; Favart, L; Fitterer, M; Forte, S; Gaddi, A; Gambino, P; Garcia Morales, H; Gehrmann, T; Gladkikh, P; Glasman, C; Godbole, R; Goddard, B; Greenshaw, T; Guffanti, A; Guzey, V; Gwenlan, C; Han, T; Hao, Y; Haug, F; Herr, W; Herve, A; Holzer, B J; Ishitsuka, M; Jacquet, M; Jeanneret, B; Jimenez, J M; Jowett, J M; Jung, H; Karadeniz, H; Kayran, D; Kilic, A; Kimura, K; Klein, M; Klein, U; Kluge, T; Kocak, F; Korostelev, M; Kosmicki, A; Kostka, P; Kowalski, H; Kramer, G; Kuchler, D; Kuze, M; Lappi, T; Laycock, P; Levichev, E; Levonian, S; Litvinenko, V N; Lombardi, A; Maeda, J; Marquet, C; Mellado, B; Mess, K H; Milanese, A; Moch, S; Morozov, I I; Muttoni, Y; Myers, S; Nandi, S; Nergiz, Z; Newman, P R; Omori, T; Osborne, J; Paoloni, E; Papaphilippou, Y; Pascaud, C; Paukkunen, H; Perez, E; Pieloni, T; Pilicer, E; Pire, B; Placakyte, R; Polini, A; Ptitsyn, V; Pupkov, Y; Radescu, V; Raychaudhuri, S; Rinol, L; Rohini, R; Rojo, J; Russenschuck, S; Sahin, M; Salgado, C A; Sampei, K; Sassot, R; Sauvan, E; Schneekloth, U; Schorner-Sadenius, T; Schulte, D; Senol, A; Seryi, A; Sievers, P; Skrinsky, A N; Smith, W; Spiesberger, H; Stasto, A M; Strikman, M; Sullivan, M; Sultansoy, S; Sun, Y P; Surrow, B; Szymanowski, L; Taels, P; Tapan, I; Tasci, T; Tassi, E; Ten Kate, H; Terron, J; Thiesen, H; Thompson, L; Tokushuku, K; Tomas Garcia, R; Tommasini, D; Trbojevic, D; Tsoupas, N; Tuckmantel, J; Turkoz, S; Trinh, T N; Tywoniuk, K; Unel, G; Urakawa, J; VanMechelen, P; Variola, A; Veness, R; Vivoli, A; Vobly, P; Wagner, J; Wallny, R; Wallon, S; Watt, G; Weiss, C; Wiedemann, U A; Wienands, U; Willeke, F; Xiao, B W; Yakimenko, V; Zarnecki, A F; Zhang, Z; Zimmermann, F; Zlebcik, R; Zomer, F

    2012-01-01

    The physics programme and the design are described of a new collider for particle and nuclear physics, the Large Hadron Electron Collider (LHeC), in which a newly built electron beam of 60 GeV, up to possibly 140 GeV, energy collides with the intense hadron beams of the LHC. Compared to HERA, the kinematic range covered is extended by a factor of twenty in the negative four-momentum squared, $Q^2$, and in the inverse Bjorken $x$, while with the design luminosity of $10^{33}$ cm$^{-2}$s$^{-1}$ the LHeC is projected to exceed the integrated HERA luminosity by two orders of magnitude. The physics programme is devoted to an exploration of the energy frontier, complementing the LHC and its discovery potential for physics beyond the Standard Model with high precision deep inelastic scattering measurements. These are designed to investigate a variety of fundamental questions in strong and electroweak interactions. The physics programme also includes electron-deuteron and electron-ion scattering in a $(Q^2, 1/x)$ ran...